LOCUS       DAFEKH010000001       107623 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.001, whole genome shotgun sequence.
ACCESSION   DAFEKH010000001
VERSION     DAFEKH010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 107623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 107623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..107623
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.001"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(98..1228)
                     /locus_tag="LP386_000001"
     CDS             complement(98..1228)
                     /locus_tag="LP386_000001"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HBL1917276.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1288..1515)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1877..3079)
                     /locus_tag="LP386_000002"
     CDS             complement(1877..3079)
                     /locus_tag="LP386_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL1917277.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3139..3342)
                     /locus_tag="LP386_000003"
     CDS             complement(3139..3342)
                     /locus_tag="LP386_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HBL1917278.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3484..4716)
                     /locus_tag="LP386_000004"
                     /pseudo
     CDS             complement(3484..4716)
                     /locus_tag="LP386_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            4879..5691
                     /locus_tag="LP386_000005"
     CDS             4879..5691
                     /locus_tag="LP386_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1917279.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6715..6867)
                     /locus_tag="LP386_000006"
     CDS             complement(6715..6867)
                     /locus_tag="LP386_000006"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBL1917280.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
     gene            complement(7058..7936)
                     /locus_tag="LP386_000007"
     CDS             complement(7058..7936)
                     /locus_tag="LP386_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL1917281.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(7975..9093)
                     /locus_tag="LP386_000008"
     CDS             complement(7975..9093)
                     /locus_tag="LP386_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HBL1917282.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9090..11189)
                     /locus_tag="LP386_000009"
     CDS             complement(9090..11189)
                     /locus_tag="LP386_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HBL1917283.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(11240..12061)
                     /locus_tag="LP386_000010"
     CDS             complement(11240..12061)
                     /locus_tag="LP386_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL1917284.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(12058..12867)
                     /locus_tag="LP386_000011"
     CDS             complement(12058..12867)
                     /locus_tag="LP386_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL1917285.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(12888..13382)
                     /locus_tag="LP386_000012"
     CDS             complement(12888..13382)
                     /locus_tag="LP386_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1917286.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(13394..13882)
                     /locus_tag="LP386_000013"
     CDS             complement(13394..13882)
                     /locus_tag="LP386_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL1917287.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            complement(13959..16655)
                     /locus_tag="LP386_000014"
     CDS             complement(13959..16655)
                     /locus_tag="LP386_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL1917288.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(17083..18156)
                     /locus_tag="LP386_000015"
     CDS             complement(17083..18156)
                     /locus_tag="LP386_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL1917289.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(18153..18980)
                     /locus_tag="LP386_000016"
     CDS             complement(18153..18980)
                     /locus_tag="LP386_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1917290.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(18981..19787)
                     /locus_tag="LP386_000017"
     CDS             complement(18981..19787)
                     /locus_tag="LP386_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1917291.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(19799..20884)
                     /locus_tag="LP386_000018"
     CDS             complement(19799..20884)
                     /locus_tag="LP386_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1917292.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(20901..21443)
                     /locus_tag="LP386_000019"
     CDS             complement(20901..21443)
                     /locus_tag="LP386_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1917293.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            21701..22690
                     /locus_tag="LP386_000020"
     CDS             21701..22690
                     /locus_tag="LP386_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HBL1917294.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            22687..23424
                     /locus_tag="LP386_000021"
     CDS             22687..23424
                     /locus_tag="LP386_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HBL1917295.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            23421..23972
                     /gene="coaC"
                     /locus_tag="LP386_000022"
     CDS             23421..23972
                     /gene="coaC"
                     /locus_tag="LP386_000022"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HBL1917296.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            23988..24620
                     /locus_tag="LP386_000023"
     CDS             23988..24620
                     /locus_tag="LP386_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBL1917297.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            24705..25352
                     /locus_tag="LP386_000024"
     CDS             24705..25352
                     /locus_tag="LP386_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL1917298.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            25357..26340
                     /locus_tag="LP386_000025"
     CDS             25357..26340
                     /locus_tag="LP386_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HBL1917299.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(26743..28257)
                     /locus_tag="LP386_000026"
     CDS             complement(26743..28257)
                     /locus_tag="LP386_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HBL1917300.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            28395..29201
                     /locus_tag="LP386_000027"
     CDS             28395..29201
                     /locus_tag="LP386_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917301.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(29376..29945)
                     /locus_tag="LP386_000028"
     CDS             complement(29376..29945)
                     /locus_tag="LP386_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1917302.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(30028..32088)
                     /locus_tag="LP386_000029"
     CDS             complement(30028..32088)
                     /locus_tag="LP386_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HBL1917303.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            complement(32365..33843)
                     /locus_tag="LP386_000030"
     CDS             complement(32365..33843)
                     /locus_tag="LP386_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1917304.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(34141..35076)
                     /gene="murB"
                     /locus_tag="LP386_000031"
     CDS             complement(34141..35076)
                     /gene="murB"
                     /locus_tag="LP386_000031"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HBL1917305.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(35149..36069)
                     /locus_tag="LP386_000032"
     CDS             complement(35149..36069)
                     /locus_tag="LP386_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL1917306.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            36182..36934
                     /gene="xth"
                     /locus_tag="LP386_000033"
     CDS             36182..36934
                     /gene="xth"
                     /locus_tag="LP386_000033"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HBL1917307.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            37798..38331
                     /locus_tag="LP386_000034"
     CDS             37798..38331
                     /locus_tag="LP386_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HBL1917308.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(38821..39345)
                     /locus_tag="LP386_000035"
     CDS             complement(38821..39345)
                     /locus_tag="LP386_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1917309.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(39338..39811)
                     /gene="tsaE"
                     /locus_tag="LP386_000036"
     CDS             complement(39338..39811)
                     /gene="tsaE"
                     /locus_tag="LP386_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HBL1917310.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(39934..40914)
                     /gene="pta"
                     /locus_tag="LP386_000037"
     CDS             complement(39934..40914)
                     /gene="pta"
                     /locus_tag="LP386_000037"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HBL1917311.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(41067..41747)
                     /locus_tag="LP386_000038"
     CDS             complement(41067..41747)
                     /locus_tag="LP386_000038"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBL1917312.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            41873..42742
                     /locus_tag="LP386_000039"
     CDS             41873..42742
                     /locus_tag="LP386_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL1917313.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            42768..43283
                     /locus_tag="LP386_000040"
     CDS             42768..43283
                     /locus_tag="LP386_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917314.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(43330..43923)
                     /locus_tag="LP386_000041"
     CDS             complement(43330..43923)
                     /locus_tag="LP386_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1917315.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(43948..44127)
                     /locus_tag="LP386_000042"
     CDS             complement(43948..44127)
                     /locus_tag="LP386_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917316.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(44204..44713)
                     /locus_tag="LP386_000043"
     CDS             complement(44204..44713)
                     /locus_tag="LP386_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917317.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(44809..45189)
                     /locus_tag="LP386_000044"
     CDS             complement(44809..45189)
                     /locus_tag="LP386_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL1917318.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            45518..46267
                     /locus_tag="LP386_000045"
     CDS             45518..46267
                     /locus_tag="LP386_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HBL1917319.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(46451..47728)
                     /locus_tag="LP386_000046"
     CDS             complement(46451..47728)
                     /locus_tag="LP386_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917320.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(47807..48451)
                     /gene="pcp"
                     /locus_tag="LP386_000047"
     CDS             complement(47807..48451)
                     /gene="pcp"
                     /locus_tag="LP386_000047"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBL1917321.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(48650..49594)
                     /locus_tag="LP386_000048"
     CDS             complement(48650..49594)
                     /locus_tag="LP386_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBL1917322.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(49596..50282)
                     /locus_tag="LP386_000049"
     CDS             complement(49596..50282)
                     /locus_tag="LP386_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBL1917323.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            50756..51076
                     /locus_tag="LP386_000050"
     CDS             50756..51076
                     /locus_tag="LP386_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HBL1917324.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            51230..52135
                     /locus_tag="LP386_000051"
     CDS             51230..52135
                     /locus_tag="LP386_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1917325.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            52132..52905
                     /locus_tag="LP386_000052"
     CDS             52132..52905
                     /locus_tag="LP386_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBL1917326.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(53086..54510)
                     /locus_tag="LP386_000053"
     CDS             complement(53086..54510)
                     /locus_tag="LP386_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1917327.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            54721..55167
                     /gene="nrdI"
                     /locus_tag="LP386_000054"
     CDS             54721..55167
                     /gene="nrdI"
                     /locus_tag="LP386_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBL1917328.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(55232..57214)
                     /locus_tag="LP386_000055"
     CDS             complement(55232..57214)
                     /locus_tag="LP386_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL1917329.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVHMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(57228..58124)
                     /gene="murQ"
                     /locus_tag="LP386_000056"
     CDS             complement(57228..58124)
                     /gene="murQ"
                     /locus_tag="LP386_000056"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBL1917330.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(58127..59188)
                     /locus_tag="LP386_000057"
     CDS             complement(58127..59188)
                     /locus_tag="LP386_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBL1917331.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(59399..59965)
                     /locus_tag="LP386_000058"
     CDS             complement(59399..59965)
                     /locus_tag="LP386_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBL1917332.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            complement(59993..61495)
                     /gene="eat(A)"
                     /locus_tag="LP386_000059"
     CDS             complement(59993..61495)
                     /gene="eat(A)"
                     /locus_tag="LP386_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBL1917333.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(61753..62874)
                     /locus_tag="LP386_000060"
     CDS             complement(61753..62874)
                     /locus_tag="LP386_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBL1917334.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            63000..63941
                     /locus_tag="LP386_000061"
     CDS             63000..63941
                     /locus_tag="LP386_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBL1917335.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(64091..64987)
                     /locus_tag="LP386_000062"
     CDS             complement(64091..64987)
                     /locus_tag="LP386_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBL1917336.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            65256..66596
                     /locus_tag="LP386_000063"
     CDS             65256..66596
                     /locus_tag="LP386_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1917337.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            66814..67257
                     /locus_tag="LP386_000064"
     CDS             66814..67257
                     /locus_tag="LP386_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HBL1917338.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(67761..69179)
                     /gene="nhaC"
                     /locus_tag="LP386_000065"
     CDS             complement(67761..69179)
                     /gene="nhaC"
                     /locus_tag="LP386_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBL1917339.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(69582..70805)
                     /locus_tag="LP386_000066"
     CDS             complement(69582..70805)
                     /locus_tag="LP386_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBL1917340.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(70836..71675)
                     /locus_tag="LP386_000067"
     CDS             complement(70836..71675)
                     /locus_tag="LP386_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBL1917341.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(71692..72372)
                     /locus_tag="LP386_000068"
     CDS             complement(71692..72372)
                     /locus_tag="LP386_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1917342.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(72374..73447)
                     /locus_tag="LP386_000069"
     CDS             complement(72374..73447)
                     /locus_tag="LP386_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1917343.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(73503..73741)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(73784..74017)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(74094..74765)
                     /locus_tag="LP386_000070"
     CDS             complement(74094..74765)
                     /locus_tag="LP386_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBL1917344.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(74852..77530)
                     /gene="mgtA"
                     /locus_tag="LP386_000071"
     CDS             complement(74852..77530)
                     /gene="mgtA"
                     /locus_tag="LP386_000071"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBL1917345.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            78189..78626
                     /gene="ndk"
                     /locus_tag="LP386_000072"
     CDS             78189..78626
                     /gene="ndk"
                     /locus_tag="LP386_000072"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HBL1917346.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(78648..79514)
                     /locus_tag="LP386_000073"
     CDS             complement(78648..79514)
                     /locus_tag="LP386_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBL1917347.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLSHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(79674..81767)
                     /locus_tag="LP386_000074"
     CDS             complement(79674..81767)
                     /locus_tag="LP386_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBL1917348.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(82516..83139)
                     /locus_tag="LP386_000075"
     CDS             complement(82516..83139)
                     /locus_tag="LP386_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917349.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(83298..84695)
                     /locus_tag="LP386_000076"
     CDS             complement(83298..84695)
                     /locus_tag="LP386_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL1917350.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(84727..85698)
                     /locus_tag="LP386_000077"
     CDS             complement(84727..85698)
                     /locus_tag="LP386_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1917351.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            86072..86497
                     /locus_tag="LP386_000078"
     CDS             86072..86497
                     /locus_tag="LP386_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917352.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            complement(86985..87686)
                     /locus_tag="LP386_000079"
     CDS             complement(86985..87686)
                     /locus_tag="LP386_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBL1917353.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(87702..88142)
                     /locus_tag="LP386_000080"
     CDS             complement(87702..88142)
                     /locus_tag="LP386_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBL1917354.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(88142..88717)
                     /locus_tag="LP386_000081"
     CDS             complement(88142..88717)
                     /locus_tag="LP386_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HBL1917355.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            complement(89565..90044)
                     /locus_tag="LP386_000082"
                     /pseudo
     CDS             complement(89565..90044)
                     /locus_tag="LP386_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(90203..90904)
                     /locus_tag="LP386_000083"
     CDS             complement(90203..90904)
                     /locus_tag="LP386_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL1917356.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(91012..92421)
                     /locus_tag="LP386_000084"
     CDS             complement(91012..92421)
                     /locus_tag="LP386_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBL1917357.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            complement(92469..94334)
                     /locus_tag="LP386_000085"
     CDS             complement(92469..94334)
                     /locus_tag="LP386_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL1917358.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            complement(94455..95306)
                     /locus_tag="LP386_000086"
     CDS             complement(94455..95306)
                     /locus_tag="LP386_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL1917359.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
     gene            complement(95616..96329)
                     /locus_tag="LP386_000087"
     CDS             complement(95616..96329)
                     /locus_tag="LP386_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HBL1917360.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            complement(96397..96723)
                     /locus_tag="LP386_000088"
     CDS             complement(96397..96723)
                     /locus_tag="LP386_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBL1917361.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELVDVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            complement(96846..97073)
                     /locus_tag="LP386_000089"
     CDS             complement(96846..97073)
                     /locus_tag="LP386_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003246265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBL1917362.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            complement(97395..98648)
                     /locus_tag="LP386_000090"
     CDS             complement(97395..98648)
                     /locus_tag="LP386_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBL1917363.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            98709..99449
                     /locus_tag="LP386_000091"
     CDS             98709..99449
                     /locus_tag="LP386_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1917364.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            complement(99535..100293)
                     /locus_tag="LP386_000092"
     CDS             complement(99535..100293)
                     /locus_tag="LP386_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBL1917365.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(100290..101318)
                     /locus_tag="LP386_000093"
                     /pseudo
     CDS             complement(100290..101318)
                     /locus_tag="LP386_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
     gene            complement(101338..104505)
                     /locus_tag="LP386_000094"
     CDS             complement(101338..104505)
                     /locus_tag="LP386_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917366.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            complement(104729..105613)
                     /locus_tag="LP386_000095"
     CDS             complement(104729..105613)
                     /locus_tag="LP386_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBL1917367.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(105708..106145)
                     /locus_tag="LP386_000096"
     CDS             complement(105708..106145)
                     /locus_tag="LP386_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917368.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            complement(106362..107273)
                     /locus_tag="LP386_000097"
     CDS             complement(106362..107273)
                     /locus_tag="LP386_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBL1917369.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
BASE COUNT        31367 a        22455 c        18436 g        35365 t
ORIGIN      
        1 aataaataat ataaaaggta aataaaaaag agtggatttc tccactccat gaaaagccga
       61 ctttttggga cgcttttttt tgccaagcct cacattttta tagccaaact tcttttgcga
      121 cttgctgcaa taattggatt ttcttccatt gttcttcttc tgttaaatgg tttccttctt
      181 ctgttgaagc aaacccacat tgaggactga tacttagatt ttccaatggt acaaattgtt
      241 gtgcttcttt tattcgttct tttattttct ccgtatcttc caaatctgga aacttagaag
      301 taactaatcc taaaacaact ttactttctt tgttactcca atgtcttaaa ggagtaaaat
      361 ctcctgctcg gtcagaatcg tattccaaaa agaaaccatc ataatttgtt gaaaacaact
      421 cttctgcaat gggttcatat ccaccggaaa acagccaaga agaagcgtga ttcccgcggc
      481 agatatgtgt tgtgatcgtc aaatcttctg gtttgtcttc cagtgcgtta ttgataatct
      541 ctgtacaaat atgggccatt tctttcggat caattccttt ttgaagaagt gcttctcttt
      601 tagtttgatc agctagaaac gcccaatttg tatcatcgaa ttgcaggtaa cggcaacctt
      661 tttcataaaa agcatgaatc gctgctttgt aagtagagga caagtcctca taaaaatcag
      721 atagatcagg ataaatctcc ttgatttttg aagaaccatc attagatagg atctcttgtc
      781 gtaaaatcat cgtgggacta gggatcgttg cttttgcaac aaaagtatca tctgtttcca
      841 ctacttcttt cagaaaagca aaatctttta aaaatgggtg atttggattg aaagataatt
      901 tatctactac ccgaatatta taagctggtg ctgcttttcc gtggaatgtt tgattatatc
      961 cagtttctgg aacatagcct tcgataccat ttagttcttc taaaaaatca agatgccaaa
     1021 atccacgccg aaattcacca tctgtaattc ctttgatgcc gactgctttt tggtcttcca
     1081 ctaatttttt tatttcctgg tcttcgattg cacgaagttc ttcttttgaa agtaagcctt
     1141 cttgaacttt ttttcttgct tctttgatcg attgcgggcg taagaaactt ccgacatgat
     1201 ctactgtaaa tggtctattt ttgctcattt cactcactct tttctttgtt ttttgtaaaa
     1261 aaaaatcctt ttactagcaa atactagtaa aaggacgatt atactcgtgg taccaccttt
     1321 tttcagaaaa aacattcttt ctctcagcct gacaataaaa tcagtggtct tggtaacgaa
     1381 agactgttcg tttttgccta cctttcgaca aaaaatcctc taaggccatt ttcgacagtc
     1441 aacttctagc tttttacacc aaccaaagcc tctcttgaac cattttctgt ctactttcct
     1501 tctcatcgga tactattaga ataaaattag aatagcatgt ttgaaagaaa agtcaatagg
     1561 gaataagaac aaacaaaaac taatttgtta ttcttagtaa tttgtttgtg gaatacaata
     1621 aagcttttct aatatgataa ttgttcagtc gtcctttcat cttagatcac ttccttaaaa
     1681 tgatcatacc cgtttcaacc acataaaaaa ggacttaatt ttgaaaaatt tcccatcaaa
     1741 actaagtcct ttttattata gttatgcaaa tttgcttatt ttctcgctat ttccgataca
     1801 tcttgaacag gagcaattcg actgaaaaca ctggtgcaaa agcatttatt tgtcttatgg
     1861 tagaaccgtg gaaaactcag actggtaata aattgtcatt ttttgaaaga atagcgccct
     1921 cttgaacatt atcaatcgca cttaccactt gttgatctga ctttgcatat aagtgaccgt
     1981 aagttcctaa agtgatttga atattcgcat ggcccaatcg ttcttgaata gatagcggtt
     2041 gaatattctg ctcaattaga aatgcaacat gagaatgtcg tagcgcgtga agcttaatcg
     2101 gtttgacacc cgctttttta gcagcttctt ttaaccagtt cgcaaaagaa taaggtggcg
     2161 taaatgttcc gtccaactga gcaacatatt caaaatttcc aatacgtttt tgcaagtcat
     2221 accactgtct gagttttaag gaaagcttct tccccaaccc aatcgttcga taagcacatt
     2281 tagttttggg agtcgaaaag taccaatcat cttttgtatt ataaatcaat gtcttctcaa
     2341 tcgttatcgt gtttttctca aaatctacat tcgaccaaga caaagcttca agttctccaa
     2401 tccgaatgcc agtataaaag agcatttcat acacaatctt ccgatggtgg gtttgaatct
     2461 tatcatcctt caattcattc atcacttttt gaaactcact gtgttcccaa aactcaactt
     2521 tcttattctc agaaggaagc gaagaaacat cttcaacggg atttttagca atcaccccct
     2581 ctttaacagc ccgatccaat acaattttta ggtgccctcg aatccgattg atataagatt
     2641 ttgataacgt ttcgccatta acttttttcc gtgaattacg tgactctgtc tggcttagtt
     2701 caaataacca atcctcaata tcgtgacttg taatatctcg aacacgaaaa tgatagaaaa
     2761 actgcatacg cttttcgaaa atgaattgcg cattctcata tgtttgactt ttgacctgtc
     2821 tctcgtacca ttttacaaac ctatccttgt aaaactcttc gaaagtcatt tgattggtag
     2881 aacacagttg attaggaatt gtcttgttaa aatcatgtgt ttccatgtac ttgtcataag
     2941 caattttggc atctttttgt gaagcataac ctcgtttagt cttctgaacc tttcttccat
     3001 tttcatctat acctagatac gctcggaaga accatttttt tgtcttttta tcttggtaaa
     3061 tatttttaat ttttggcatc gttccattcc tccctgtact tgagaaaagc tactttaata
     3121 gtaccgcgct tgtactgttt attccgcaac ttgaatgtga aaaagatgtt caattactcg
     3181 ggatggcacc acaccaactt ggcgattatt ataaaaatca ataccttcaa tccttgcaag
     3241 atatgccttg ctctctttaa tcattcgtgc agcttgacta ggtttaaagc ccatctctat
     3301 caaaattgca cgatttacca tgaaatcaca ttttgtttcc attctctcac ctcctgattc
     3361 tttactcctt ttaaaataat cctctttata atctattgtt tctcattcga tggttgtgtt
     3421 atactcgtct tgtcgaggcg gagtacgttg cacaacttgt tgtgtaagca gtactttgct
     3481 tttttagtag cttgttttct catttgatat actttgtaat tttcgttcat aatactcaac
     3541 ctcctcctga taatactccg ggtctgcctt catattttgg agaagtttga tctgtcttgg
     3601 attcatttct ccttgttcaa taatcaaagg caacaaggaa gaatgaaacg tttgatcgac
     3661 ctgtgcaata aaaactaatg atggtgaaac accatgaatt aaccaactca tagttttctc
     3721 aaaactttga ggaattgtat ctaaagaaat ggtgattgcg ccataattgc taataaaggc
     3781 tgcccatttg gcatcaactt ttgcacctag atcatttgga tcacggtcat aaaaacaaat
     3841 tgctccatta agtaactcaa agaacagttt ggttaaatca tgggtttttg aaataatctt
     3901 tgccaagctt tgcgctttct cttttcgata ccgtagttca aagcgattct ttacttttgc
     3961 ctcttctaaa ggaattcctc gtcgcttccg ttgttcatgg tccttctgat aaaagcaaaa
     4021 acgacactga ctcttctttg agcctaaata caaggtctca ccatttgatt cattgtttat
     4081 gatatccgta ccgccatgag attcactcac ttgaaaagtg gtccacacat ggcctagtat
     4141 taccttatgc ttaagttctg gaatgctgag actccccaca aaatcatcta aagtaaaatc
     4201 aatccgtgta aagttcccct gataatctaa taccttacga aaaaactgtt gccaatttgt
     4261 ttttcgtgtt tttagccatc ttgctaagtg tttacagcct tgacctgaaa actccatcac
     4321 agttccttta accgcatcgt caatggaata ccgaatcgtg attacttgat tccacacgta
     4381 ttggccaata tagccctttg gcgcataatc cagttcctca aaacgttcaa tgggcatttc
     4441 aataatctct tcaattagct ttaaatgttg attcgagaaa aagtgaatgg ttagataatc
     4501 aatcaaaaca cggttaactg gaacgacctc ttcttgcaaa ctatccaaca caagattcaa
     4561 tttttcttca cttaattgtc tcgttccttt ttctactttc gataataact atctcgaaat
     4621 ccccactttt tctgctaaat atcgttgtgt ccaccccctt tcttctcgag aaactcgaat
     4681 ggcttcaccg agatcatgtt gattaacttg gttcatcgac aaacctcctt ctgctattta
     4741 cttgtcaaag aacctattga acttatttta agtacatttt tattgtacgc ctgtatttat
     4801 tttaagtcaa tatgttttga ctttttttaa gtacacacgt atactaaatt taagaactta
     4861 tcctgaggag gagttttcat ggagatagac aagcaagcag tcggcaatcg aattcggcag
     4921 attcgccaag aattaaagtt gagtatggag aaatttggca aactaattgg tgatttaccg
     4981 cgaagtacag tcaataactg ggaacgtggg atcaaccttc caaaaaccga aacccttcac
     5041 caaatcgcag agataggtca tgtcaccaat gaatatcttt tgtatggtga tcaagagaat
     5101 caatacattt tagaaatgct ccaaaaaaag gcaggtaagc ttgatcctaa gattgaaggt
     5161 ctcatagtag acgaaatcaa acacgctgac cttgttagtg aaaaagaaat ggatcgaatg
     5221 attgaatttt ttattacaaa tctcattcca ccaactgaac aagaccagtt tactttccaa
     5281 tgtatcgatg aaaaaaagca gctttatctt ggttcaacta attttggtaa ggaagcccag
     5341 ctctatttgc aacatgataa tcaaaatcat attctgcaca tgatgccctt taccttctcc
     5401 aactttagtg tggatcgcat actcgtctat ttagcaaatc aaaaatccta ttcctatttt
     5461 gggaaacatt tacccaagga actaggtgag aaagccatcc ttctatactc aattaatcaa
     5521 ttgaccagcg atgtgcgaat tgccccgttg gtctattcag aagaaaccgc ttcttatcag
     5581 tacacagagg acaatcaata tctactagaa cagcaatatc tttatctacc attcgtgatg
     5641 gaagtcgaga aagaacgcct gttaaatgca gcgtatccat catcaaaatg aggtgacaaa
     5701 attgataagc acgtgacaaa gaaaatactg ctaggacact ccccaatggg tagttgtcac
     5761 agtttcctgt tctttgttag ccccctgtta gaaccggggg ctttattcct gcagtccggc
     5821 tacgccttcc tgcaatagac aaaactccag atcgggtaat tcgcttgtgg cgaaacccga
     5881 cctggagttt gtctctgtat tttgaaccct aaaaattaat caaacagact gatattctca
     5941 taatcagcgc gaaataagcc attaagtaca gttttcctac ctatttttga taacccgctg
     6001 gttagttaat attccttttc cgagagagat aaatgattgg ttaaatctat atacatctca
     6061 acctttaaaa atgttttcga aatacttcat cagtacatgt catacaaatt accagtgcat
     6121 tctcaaattc tagttcttta attgatttca gttgaggagc agttactttt ggcggaaatt
     6181 tccatttttg tccaaacctc ttcccccgat gaaatttctt tgttgcaatt attgcaatga
     6241 aaaatttttg tttcaaaaat atacataatt acttcctcca ataaaaacta tctacctctc
     6301 aaattatttt tctctaataa gaaaaacaga aaaggtaata agatacaaca gtgatgattc
     6361 ctaataaaga aaagactaca ataatatttt tctaacttat cgccttcaaa gaaatagttt
     6421 cttatttttc actaaaataa aaaatttatt gcaaaaaaaa tagaagtgac aaaattatca
     6481 atcatttcaa ggtaatataa ctacctgagt ttattatcga ttaaaatgct aactacattt
     6541 gcaagagaag cgagagttaa aggtaaatat agaatttcta cttttttagc aatagaaata
     6601 ggaataaaat atttaaaatg tatagaaact ttcttttttt ttcttgctat ctttttataa
     6661 tcacaactct ctataataga attacgattt attttatacg gctgaaaaaa tctatcacca
     6721 aaaaaattca aacattaagc caaggattat gaagtcaaca tttcgaaaaa tgaacataca
     6781 ttggtaagca actataacta ttaccacaga cataaagtaa cacaatatat tactatttaa
     6841 gtgtacgcca ccagtgaata tcctcaaggt atacagcgca caacaaaaag aaaaaaggaa
     6901 acgcagaagc atttcctttc agtgatttaa tgaaaacaac acgatttgac ttagagcctt
     6961 tttatttgaa ttcattttcg ctttatccaa cttcatttga tcatttgatt actcggttaa
     7021 atacttttga catgagtatc aatgaaacat tcattaatta tggttgctta tttcttaccg
     7081 cttttctggc caatgctaat ccgccgatta ttccggcatt atcacctaat tcgggcgtaa
     7141 taatgtagct atcaattggt ggtatttcaa catatccatt tataagctca acaaatttat
     7201 cctgaacttt tttcttcatg tgttcttgtt tcattacacc accgccaaaa ataattctat
     7261 ctggcgaaaa catcagtgtt gtattgtatg cacattgggc aaggtaaaag gcttcaatct
     7321 gccaaaacga atcgtcagcc aataaattct ggccttttac acccaaccgt ttttcaatcg
     7381 ctggtcctgc tgccatcccc tctaaacaat cttggtggaa gggacagttt cctgaaaaat
     7441 tgtcctttgg atgtcgcttg atcaacatat gccccatttc cggatgactg aacccttcca
     7501 cgaaagtccc attgaacaag gcaccacctc cgatacctgt tcccacagtg aagtatgcaa
     7561 cacctgctaa ccctttgcca gaaccagcaa catattcacc atagcaagcc gcattgacat
     7621 ctgttgtcca ttcaatcgga atattgaaat attgctttag cgttcctaca aaattgaaat
     7681 tttgccaagc aagttttggt gttgatgtga tatgaccgaa actcgttgat ttgcattgaa
     7741 tatcaattgg accaaagcag ccgaccccga tgcctgccaa ttgttcctta aaaggtttaa
     7801 aaaaatcaat gacctgcttc attgtttcaa ctggagttgt tgtgggaaaa ctgactcttt
     7861 ccaaaatcgt taattcctca gtaccgactg cacagacaaa tttagtccct ccagcttcaa
     7921 ttgccccata tatcatcata ggttcctccc ttcgaatatg tgaaaaacac ttcattaacg
     7981 cggcaagcgt tctcgatcag tgaaatgacg tttagtattt cctgaagctt ctgttgaata
     8041 ccagtaagcg acactagcaa catcgtcttg ccgctcaaat aagcgaacat catcgttgcc
     8101 gatttgttgt aaagtgaccg ataaatcttc ggtaaaacag atggggtctt gaagatgcca
     8161 acgataaaga ccatgtcgtg gcattgcgtc gtcaccaaag gcatgaacgg cattcaattt
     8221 tcccgtttca aaacgatctc ttgtggcatc tctatttgat tggtaaggat accctaaaaa
     8281 ggctgttgaa tagtttttcg catgtggacg tccgaactca tcgtactcat gaaaggccca
     8341 cgccccgcca aaataatctt ctgaacctgt tgaggttacg gtcggatact cactatcccc
     8401 atcaatgtag aatttaaact cgccttcgcc ccaccaataa cgttctaggc aggtaagcgc
     8461 aaggtaagta cccacgtaat agccttgacc ctttaatcga tcaattaact tataatcctc
     8521 ctgtaatttg gtaatgcgtt cccgatgcca atttgcgtga aaatataggc tattttcttc
     8581 caattcgtcc accaaagcgt aatttatcgt ataaaaaaat gaggacatat ccttcggatg
     8641 taaattctcg atcgtaattt tagcggatgt ttggaaaggc atttcgaaat aggaattaaa
     8701 gccccctgta ggattaacca ctatcggcaa cgagttcacc tcgcaacgct ctccaaaccc
     8761 attacaaaag aaatccccta aaggactttc aacagcaggg ctatccgacc catcccaata
     8821 aattcttaag attaaatcac gtaaaacaaa actgccaaat tctgttcgat cacgaatcgt
     8881 catccacata tgacgaatta ttcccgttcc agtaatatcc gcaatcacag tttcttcacc
     8941 agaagtcagc ggaattgcgc cacgaccttt gcggcttggt cctagctcgc ttggcaacat
     9001 cgcagcttta cctttctcgc ctgttggatt ttcgggagtg attgctcgac tctggatttt
     9061 tttaaattgg gtaatatttt ttagtatact catctttttc tcctttgaat gtgaatcgtt
     9121 tttccctttt ctacgtgaag aatttttttc gtatcactta ttttcaatgg cttttctgac
     9181 aaatttgaaa tactcaactc ggattgcgta cattcaatcg aaatgaaggc ttgaccgaac
     9241 ttcaaattct tccaagaaaa cgttaaatta tcaacaggat caatttgcaa tactcctttt
     9301 ttgaatttca atccgaaata ttgactgatc attaggctga caaaaagacc cgatgcccag
     9361 ccgcatttgc cgcagccaaa gtctcgcacg acttctcctt gttgagcctc taagcgatac
     9421 ggccaccacc accacgaacc gtctaaatct gccaaacaaa ttagttcttc taatcgggtt
     9481 acgaaagctt gagggttgtg cagctcgctc attaaaacag tgataaagcc aggaaaagtg
     9541 gcgccggatt ctaatcccca agtgatgcct ttgatttcct cgctataggt tggattgaaa
     9601 gaactagcag aaaaggccat ggtgttctga tataaatgat ctttattatc taaaaattga
     9661 taaaaaggca tcaacgtagt gtctgattct tctccatcat gcatcaataa attaattttt
     9721 ccatccacaa tcacatcact taaaaagatt aacccttgct caagaatcgg tttttgatag
     9781 tgcttcactg aataggttgt tttctcctca tcaccgattc cctccaaaaa ttgctcacca
     9841 aaaggaccat cgatagtcat ttgtttacaa attgattcct ttagtttaca ggcaatgttt
     9901 ttgtatcgct tgctaagact cagttgttct agggcttcaa aaatttctgc aagtccaata
     9961 caggccttcc aaagacaaag attgctgccg gtatgatact ttccaagtgc aaaggcgtct
    10021 gataaccaaa cagatggaaa aagcattggt tcccctgacc gacgttgagc taatatgtcc
    10081 tcaataattc ttgaagcatt cagtagaacc tgcggacacc gctcaaagaa ttttgtatcc
    10141 ccagtatgtt caaaataaag actagccagt aacgcactgg ataacgaatt actcagagaa
    10201 tgattgatac ctcctgtaaa ttttgaacca ggaaacttaa cgccatattg atcaaaccat
    10261 agaaccgttt tttgacataa ctccggttca aacatggtga atggcaatga tgcgtaatac
    10321 atatccttat tccaaattcg attagtagca ggatagctgc cccaattgct gccgacgacc
    10381 tgtccctgtc gattcatacc gaaactagaa aagctttgat aaagtgcacg acgatagaga
    10441 tggacaactc tatcgtttgg cattgacagc tgcccaaata gctgagcaaa atagttcaat
    10501 gtttccttca gccatttttc gatatcagat tcctgaaaag tcattacttc ttcaaaagca
    10561 tttgggtcca caaaagcaat ggcgaagctt gccacttcct gttgtgcgat cgtgtcctta
    10621 tttccttttt gagaaatcaa cacattttgc tgatccgaat acttctcttg atacgaaggc
    10681 acatctttca ctgaaacttg aaggctttcg tgtgtttcat tcacaatgta aacctgttga
    10741 acaagcatac ttaaacgctt attagccagt atgggagcaa aggatactac aatgacctta
    10801 aacgtcgaat aatgatgaat atatctaggc aaacagtctt gaatcacatc gacttcaata
    10861 cgatgatccg attctgacaa atggtagaca atcccgttta cttcaacctt taaggataac
    10921 gaattggttt gagagagctg tttattgacc caaacacctg gtttttcctc agttagtaaa
    10981 ttttctcgat aaaaggtcaa cgtttgaatc gtcccgcaaa catcaaggtt tgctaatgtc
    11041 ttttgattac ttacatcgaa ggtcaatccc tttacatcag gaatattccg atagtagctg
    11101 tattcgtttg aagtagtcac atttccgtcg tttaactcag cattaaaaaa tgggtgtttg
    11161 ggtgaataaa ttacttcatt aatagtcatc ttttccctcc ttgctaaaaa aactgcagcc
    11221 tagtagctgc agcttcctac tatgcgattc caagtaatga caataaaatt cccaagacga
    11281 ccattccaaa aataattttg atgacgccga cttttttatc tagtaatttg aaacagctca
    11341 atgttaccaa taacggtaca attcctttaa aaatactatc gaggatttct tggacattca
    11401 ttagttcttc gcccttcatt gaaaagctca aaacggtatt gaatttgacc atactgatcg
    11461 tcattgcacc taccatgatc agacccaaga tactagcagc ttttgtcaga atttcaatta
    11521 acccgttcgc atacagcttt tcaatatatt tagagcctaa tgaatagcct aaaacgccgc
    11581 catagtatcg catcaagtaa ttaggtatat tgaacataac taaaaagata attggtgcca
    11641 aaatatttcc ggcattggct aagttgatcg ctagtcccgc ggtaacgaca cgccaaactc
    11701 cccagaacaa tgaatcgcca attccagcca atggtcccat caaactcgtt ttgatcgcgt
    11761 tgatactttc cacgtcaaaa ccagcttttt cagaattttc cttctccatc gatgccgcaa
    11821 tccccatgac aaaggacgcg caaggaatgg tcgtcgaaaa atactgtgta tgacgttcca
    11881 gcgccgcagc tcgatcttct tcacttttgt agaaatgatt aatgaagggc atcatagaat
    11941 aggcgaaacc accgccgccc atcgtcaccg gattcaccga agcatacata gtcatcgagc
    12001 gccaaaacat cttccgaacc aattttttct catctttaga aattccatca gctaatttca
    12061 ttgaaagaaa tcctcctctt cttggtcaag cgttgcattt acagcagcat cgctttgaac
    12121 tgcatgaaca gatatatttt ttagttgtag atctctttgg gctataacaa ttgcaataat
    12181 cgttccaact gcggcaattg caatcaatgg taactcgaga tacgccataa caacggcccc
    12241 aaagaaaaac cacacagcaa tatttttact ccaaagcatc cgtaacagca tcgccatccc
    12301 aactgccggc agcagatttc cagcgactgt taatccgttc atgatgacct ctggaatatt
    12361 atccaagacg cttttgacaa catctgctcc aaataaaacg gcaaagaatg gaataagagc
    12421 ataaagcgca tagtggacaa accacataaa gaagtgcaga ttgatgattc ctttttgatc
    12481 accagatttt gcaaatttga aaaatttagc agccatcggt ccacatacaa aagaaaaaat
    12541 catattcatt aactgtaatc ctaatactgc tagtggaaag acaatgggaa taatcgcatc
    12601 cacgtttcct cccattttga ttgcgaacgc tgtagccagc ccagcagcca aagaaggctc
    12661 cgccgtacta gagattccga tattgacgac acccataaag atggcttcta gtgacgcccc
    12721 gacaatcaac cccgtctgca aatcccccat caacgctcct gctaacggag caacaacaat
    12781 cggacgactc agcatggaca tcccgaacat ttcatgtcca gcaactccaa taaaaacggc
    12841 caaagcgact acaaatgcat catacataat ttttctcctt cctttttcta aaaatcactc
    12901 aaaatagaga tagctgaacg tttttccatc gccggtgtag gctgaaaaac ggtatctgga
    12961 taaagttcaa ctaattcttt taagtcttga atttctgacg tcgttaacat cacttccttt
    13021 gataaggttt tcttatcttc cgatggcggt gtcattttcc cagcattccc cacgttcatt
    13081 aattcgattt ccgttgggaa agctttcgca acttttaccg catctttgac attagggact
    13141 aaaaccatca agcgcatgtc cttcgcccgc ggatctttta acaaatgaat cgcgtcatca
    13201 actgttttaa taatgacttt gacattcgat ggtgcagcca tcttcaatgt catcttttga
    13261 atatcgttgg tagccgcctc atcgcttgct actactaacc cggttaaatt tagactcttt
    13321 gtccaagtca tcgctacttg tccatgaatt aatcgttcat caattcgcac tgctttaatc
    13381 atttttcttc ctcctaaaaa aaatcttcct cttcatttac tacatgtacc tcatcaagaa
    13441 tggtcatctt taattcctgt tggcatttat ttaccagttc ctgaatatcc tcctttgtta
    13501 attccttggt tgccaatact atttcgagca gaattggcag attaaagcca gacaaaatag
    13561 ttacagcaat ctctttctcc aaaaaggttt tggtaatctt ctgattgaca cttccgccaa
    13621 ataaatcggt aaaaacaaaa atctgatcct gctcgttcac ctggtttaca aatacattca
    13681 actcctgttc aaaatcacac tcatccacat aagcattaat caccgtaatc tcttgaacct
    13741 tccccgtcag taattgaata ctgctaagaa agcctgaagc taagtgaccg tgagtcgcta
    13801 ttagaatttt cttcatatgg ttaattcctt tctttctgtt cacttttata taagcaattc
    13861 ctgtgccaac ttttaaaaac attggtttaa tcacgttaat tcacattaaa aaaagtgtct
    13921 aacctaaaaa aaacagatta gacacttttt tagacacttt atttttgaat atacggtcct
    13981 aataattcat agagcagcga aagctcataa gcattgactt taaaattata tttcatctcc
    14041 attgattgaa aaatacttct agaaacataa taaaattcat cttcatctgg tttcaaatca
    14101 taattcggtt cttcagattt ttctgtccga gccaagaata aacgttccat catcaatgcc
    14161 gtatgcatat agagatttag ttttacacgg ccatttaaag tgaaatgata gtaattttca
    14221 tatttagaaa tgactgtttc cacttcactc atcacgatcg ttgggttcag aaagttcaaa
    14281 cggtccgcaa ttccttccaa cgaaaagaat tttactagct cctgaatcaa gcggttaaat
    14341 tctgccggct tcatttcagg actcaaaata tgctccaaat tggctgctcc atcaccgtct
    14401 aagatgtcat aaacattaat attaggaatt gaaaaggaac gtggaagatc cgaagtcgtg
    14461 atgaccaatt ttgtcttgtc aaaataagtt tcatcatttt ggtcgattaa ttcacgtagt
    14521 tctctgtagt ccttcgtgaa aacttcgatg gattcatccg ataaatgatg acgaaaaaca
    14581 tctttcaatt tgtccgaaat ccccaaaccc gacatacagg aaatgataat gttgctactt
    14641 tgagaaaagc cttcaaagta ttgaacattg attgaatact tgtctgctgc atcctccgca
    14701 atctgtttaa atggcgcatt catcgtcatc ttcaagccaa tatcaagtgc aatggaagtc
    14761 gtcaaattat tcagaagaag taactcccct tttaaatcgt tcttgatctg tgtgtaaatt
    14821 tgatttaaag agcccatatc tacgatcagc actagactat ctgtattcac ttgccgtttc
    14881 acgaaattcc ttgtcgattc gacaatctct gacacattac tctctactgg catatccaac
    14941 gcttcaaaaa cataattgcc gcataattga ttcactactg cttgaatgct gctagccgta
    15001 ctatctccgt gagcaagcaa caggcccttc agctcgatgg attcatctac ataatcagat
    15061 aaagtcacga caataagcag tcttagaaag ttctcgtcct tttctgagag cggtggtaaa
    15121 tgctccaaga actgattaca taagtaagtc gtccgaggta gatttgcagc taatgtacga
    15181 tttatcccgg ttaagtctgt cttatagctt ggggaaatga cataggatct gctaataatt
    15241 tctgcaacag gtccactcgt cgtcaatccg tacgtttttc ctaaaacgga tacccagacc
    15301 tttctaaaca tctgaatcat caattttcta ctcattgata aaaaagaatc cttatcaatg
    15361 tgatgcacca aatgctgtac ttcattcttt atcgaagaaa aattttcatt gaaattacct
    15421 tcatttatca gctgagtaat tttttccaaa atcgaatcat aatcaaacgg tttgattcga
    15481 tccgttttta tcttttgatt tttctttatc aataaactag caatcggcaa gctttctact
    15541 tcggattcca gcatatttaa ctgaatcaag atctcatttt tcccaatcgt taatggttct
    15601 tcttgtgttc gactatacac atccgcacaa ctgattttaa tgatattctt cagcttacca
    15661 atattcccac taaagggatg agataacatt aaagacaagg cttctcttga aacaataata
    15721 tctttttgta aaacatccgc ttcattttga aaaaataatt gaatcagctc taatcgttct
    15781 cgaatggggc gatcttcaaa agttggcaac ataacactaa tttgaatacg ccgatcaaag
    15841 gtgtctaata aataattttc acctttttcc gtcgtggcga aaataaaacg aaccttagca
    15901 gaatgccaat ttacattttc accgactgga cgatagtttc cagtatcaat aaatagaaag
    15961 agcttttctt gattttcttt cgataggcga tggacctcat cgagaaaaag atagccgttg
    16021 ttggccgttg ccaataaacc atcggtatcc ttttcagccc ccgtaaaggc ccccttcttg
    16081 tatccaaaca gtgttgccga aagcagttcg ggattgtccg cataatcggc acagtttaag
    16141 atagcaaatg gtgcatcttt ttcaataatt tgctcatgga tagcgtattc aaaaattttt
    16201 gtggctaaaa aactttttcc aacacccgtg gctccattta ttaatacact gagtccgtta
    16261 ggcggatatt tgacagcggc tatacatttt tgaatgacct ctctcagact tccgtcatga
    16321 ccaactacag aatgaaaggc ttcgtttatt tgctccgtat tatctacaac cgcatattca
    16381 tctaaaggct tccacaaaac aggctttccc ggtaatttct cgaccttttt atcttccact
    16441 aatctcgtca aataatggct ggcattctga cgagagatac ctagattctt cgaaattttc
    16501 tcggcagtga cagaagacat attccctgtt agtcgtatca gctcatcaaa aactcgatct
    16561 ttagcgctct ttttcatttt ttcctccagt ttaatgtgtc taaaagcata ataaactatc
    16621 ggctgcaata tgtctattct atatttgtat tccaattttt actttgaaac acaaatagtc
    16681 gaatatttgc ctcagatatc tgacaaaata atttatctac caatttagtt tttatctaat
    16741 atgattttta tgttttttca tagctacaaa tattgaactg gattcatata ttagttttat
    16801 taatagatta cagaagggtt aagtatattt gcatagtttc caattacttt atccttctgt
    16861 aactttttca atcttagatt tactagcccg tctcgggccc tattttacaa tggttttgtc
    16921 cacttttctc tggtagaaaa acgtggtaga aaaaataaaa taacacaaaa aaagcggcgt
    16981 ttcatccgct tttggtagaa gattggaaaa ctcagataga aaaaggacga tttttagctc
    17041 tttagaacgt tgataagtcc ccattcttac tgagttttgc cattatctcc tatacatctt
    17101 gaattctaag aataggtcat tatagatgcc taggtatttc gatcctagat ctttgtagac
    17161 ttcaagatgg gagatcgtgt catcagatgg atagaattgt tcgtccgacg aaatgtcttt
    17221 tggcaataac gcttttgctt cttcatttgg tgtagaataa ccaatatact ctgcattttg
    17281 tgccgcattt tccggttcta gcataaagtt gatgaaatca taggcacctt ctttattttt
    17341 cacggttttt ggcataacga tattatcaaa ccaaagattg gatccttctg gtgggatcac
    17401 ataatgtaaa tgttcatttt cccacatcat atcggcagct tcgccagaaa atgtcactgc
    17461 cacggaggct tcttcattga tcatatacat tttgatctca tctgccacga ttgctttgac
    17521 atttggtgtt aaatgattca atttatttgc tgcttctgtc agctgtgcca tattcttact
    17581 attcaaagaa tagcctaaac tattcaaaga aagccccata acttctcgtg caccgtcaat
    17641 cagcatcaaa ctgtctttta attccggctt ccacaaatca tcccaatgct taatttgatt
    17701 tgcatcaaag aatttatcgt tatatacgat ccctaaagtt ccccaaaaat atggaatcga
    17761 atactgatta tctggatcaa aatccaagtc taaaaatcgt ggatcaatat tatttaatcc
    17821 tttgatcttc gaatgatcta atggaagtac tagtttttct ttgatcattt tttggatcat
    17881 atattcactt ggtatagcga tgtcgtagtt tgtcccacct tgctggattt ttgtgaacat
    17941 cgcttcatta gaatcaaatg tttcataatt cactttgtat ccatattctt tttcaaattt
    18001 cgtgatcaaa ctaggatcga tataatctcc ccagttatag atggtaagta cctttgctcc
    18061 actcatgcca cttgtttttt caagttgacg aacaccaagc agcagcaccg caataatgat
    18121 gagaatacct aaaaacagag attgtaattt tttcatcgca gccgtgccac cccctcgcgt
    18181 actcttctgt ttttcttcag ccgttttgga cggttttctt tactaataaa gtagtatcca
    18241 atgaccaata tcatggagaa caagaaaact aacgcactta gcgcattgat ttctaaactg
    18301 attccttgtc ttgcacgaga atagatctct actgagagcg tcgtaaagcc atttcctgtg
    18361 acgaaaaatg taaccgcaaa atcatcaaga gaataggtaa atgccataaa atatccagct
    18421 atgattcctg gagaaagata aggcaaaatg atatttttga ctacttggaa attattagca
    18481 ccaaggtctc tagccgcatc gaccattgaa tcgttcattt cctgcaattt tggcaagacc
    18541 atcaagacga cgattggaat gctgaaagca atatgggaaa gcaatacact ctgaaaacct
    18601 aatccgaatc ctagtagtgt aaagaaaatc aagaaactag caccgataat aacatcagga
    18661 gagactaata agatgttatt catgctcaac aacgctgtcc gtgcacgtcg ttttttcgtg
    18721 taatagattc ccatagcccc aaatgtcccg atgatcgtgg cgatcaatgc agataagaaa
    18781 gccagcatga acgtattcaa tacgataatg atcaaacgtg tatcttcaaa aacagcttca
    18841 taattttccc aagtaaatcc tgtaaagctg ttcatcgttc ctccttcatt gaaggaataa
    18901 aaaatcagat agaagatcgg tgcatataag aataaaaaga cgatccctaa ataaagatac
    18961 gaccatttaa attttttcat ttatgagcga cctccttttt tcttctcgcc tgtcaggagc
    19021 atcacgatga acatagcaat gattaaaatc acaccgattg tagaacccat cccccagttt
    19081 tgtgtaacca agaaatgctg ttcgatagcc gttcctaaag tgatcacccg atttccgcca
    19141 atcagacgag tcagcatgaa taaagaaaga gaaggaataa atactgcttg gacaccactt
    19201 ttcacaccat ttaatgataa cggaaaaatc actcgtcgga aggtctcaaa gctattcgcg
    19261 cctaaatctc tactagcact gatcaaagaa ggattcatct cttccaatgc attgaaaatt
    19321 ggcataatca taaatggaat ctcgatatac gttgccacga acagaaaact gaagtctgtg
    19381 aataatatct gtttcggccc gatcccgata aaatcaaaga aatgattcac gctgccgtgc
    19441 acactgaaaa tcccaataaa tgcgtaagct ttaagcagca gattcaccca tgtaggcaaa
    19501 ataatcagca tcagccataa ttgcttgtgc ttcagttttg ttaaaaaata agcagtcggg
    19561 taactgatga tcagcgtgaa aaacgtgatc aaaaatgcat accatacaga attgatcgtc
    19621 atagaaagcg atgtccccga cgtaaaataa gatagataat tattcagcgt gaattgccca
    19681 ttcatatcaa aaaaagattg ataaatgatc attaatacag gcgcgatcac gaataaaccg
    19741 agccacaaaa tataagggac ggaatagatc ctgcgcattg ttttcattct tgtcccccct
    19801 attcttcgta gctgtcaaga cgtgcatcga attcttcttc agactcgttg aaacgcatga
    19861 catggatatc ttctggctca aaggccaatc ctactttgct tccttcttta gcttttttcg
    19921 ttgaatggac catccattca ttttgctgtt catcataaca gatgatttca taatggacac
    19981 cacgaaacag ctgagtatcg accgttacga ctagttttcc tttatctggt gtcgtgatcg
    20041 tcaaatcctc tgggcgtaaa acaacttcaa ctggttcatt tagacgcatc ccgccatcga
    20101 cacattcaaa ttgcttacca acaaactcaa ctagattatc ttcgatcatt acaccgtcca
    20161 cgatattgct ctccccaaca aaatcagcaa cgaaatgatt gattggctca tcataaatat
    20221 ctacgggtgt accactttgg acgattttcc ctttattcat gacaaaaatc tcatcactca
    20281 ttgccaacgc ttcttcttgg tcatgagtaa caaaaataaa cgtgattcct aatcgttgtt
    20341 gcagatcccg cagttcatac tgcatatctg tacgtagttt caaatcaagc gccgataacg
    20401 gttcatctaa tagcaatact ttcggttcat ttacaattgc tcgtgcaatc gctacacgct
    20461 gtctttgacc accagacatt tcactaatct cccgtttttc gtatccagga agctggacca
    20521 tacgcaaagc atcttttacc ttcttttcga tatctgattt ggacattttc ttgatcttca
    20581 atccaaaagc aacgttatca aaaacattca tatgaggaaa aagtgcataa tcttggaaga
    20641 ctgtatttac ttgtcgctta ttagctggca aatcattcaa ccgtttccct tcaaaataga
    20701 tgtccccttc tgtagcttcg gtgaatccag ctataatacg taggatcgtt gttttaccac
    20761 agccggaagg accaagcagt gtataaaatt ttccttgttc gatctcaaaa cttacttttt
    20821 ttaatactgt ttcatcatca tagcgtttca ctacttgatc aaatgaaatg attggtttcc
    20881 ccacgttttt accccctata ttacaaatat gattgcgttg caacaatcaa tacttttgtt
    20941 cgttttttga gatgattcct taattgatgt tgttttgtcg cttgataata gatcgactgt
    21001 cctgcttttg ccacatagac cgtctctcct aagcttaact ctaattcccc ttctaataca
    21061 aaaataaacg tttcagataa tgaaggttca aacgtcttat attctcctgc accttcaaaa
    21121 gtcagcaaga caggctccat ttctttttca ttcgaatcag ccacgagcca ttccaattca
    21181 tacccgtttt cttcatcgaa ataaaccgta tgatcttctt ttgaataaac cacttgcaga
    21241 ttcgctgctt cttgatgaaa aaattcttct ggagtcacac ctaagacttc aagaatagaa
    21301 aagaatgttt ccattgatgg tgaacttaaa tctcgttcca actgggaaat ataccctttt
    21361 gacaaatctg tgcgttcgcc tagttcttct tgtgtcaaat tcttttggat gcgcaaattt
    21421 cttaacttct caccaatttc cataatttcc tccgaatcga agttttctaa tagtaaactt
    21481 cctgtttact accactcgta ttagtatacg aaatttattg aaaaaggcaa ccctttgtaa
    21541 aatttttttt gctgaatatt tctttatctt ttggaataaa ttctagttgt ttgattcttt
    21601 atttttcacc taatttttgt ctaaatttac ggaagaacaa gaataaaaga gtaggcttta
    21661 tggtatgata aaagaaaatt ttaaaaggag tgtctcacga atgaacgctt ttcgatcttt
    21721 tcaggtaata aaggaacctg ttttccatac agcaatcagt gatctgccat ttactgagtt
    21781 ggctgaaaat gaagtcttgg taaaaattgc ctattctgat gtcaattata aagatgcatt
    21841 ggcaatgagc gagtctggtc aggtgatacg aacatatccg atgactccag ggattgattt
    21901 atccggaact gtcgtccaaa gtaacaatcc acgtttttca aaagaagatc ttgtacttgc
    21961 tactggtttt gggcttggcg tcacccatcc aggcggttat agccaatatc aaaaagtacc
    22021 aggagactgg ttagttcctc taccaaaaaa tatgacgctg cgtcaagcga tgatccttgg
    22081 tacagcaggg tttactgcta tgttgtgtgt gaacgcttta atccgtcaag gtatgacctc
    22141 cgataaaaaa gttgtcgtta ctggtgcttc tggcggtgta ggcagtacag cgatagccct
    22201 gttacataaa ctaggattcc agtcaatcat tgccttttcc agaaaagaag agtctgtcac
    22261 atggctaaaa agtctaggtg ctttgcaagt cgtacgacct gatgaatttc tgccagagac
    22321 aacaaaagct ttaggaaaac agcaaatcga ctatgtcatc gacacagtag gtggcgagca
    22381 gctaagcagt cttcttccat tgatctctta taacggtgca gtagctttat gtggcaatgc
    22441 tgggggaatc aaactaaacg cgactgtctt gccttttatt ctgcgaaaca tccagttgat
    22501 tggaattgat tctgtcaatg taccaataga tcaacgtctt tctttatggc aacagatggc
    22561 ggatttgcag attgcagatg aactggtcgt ccaagagatt actctggatc aattgcctga
    22621 aacagcatct aaactacttg ctggaacaca ccaaggaaga acactagtaa atgtaggtga
    22681 ccataaatga agattctaat cacagctgga ggaacgactg aaaaaatcga tcaagtacgt
    22741 gctattacaa atcattcgac aggacgatta gggcaagcat tagctgatta tttagctgcc
    22801 aatccggata ccacaatcga ttacgtgact acgaaacaag cactgaaacc gaaaagacac
    22861 tccaatataa cgatttatac gatcgaatct gcactggact tatttttaca attagaagaa
    22921 ctaacgaaaa aagaacacta cgatgcgatt atccacagta tggcagtcag tgattttact
    22981 cctgctttta gtttttcaga agaacagctg gcaaaaaacc tacccacttc ttcaacgcaa
    23041 gaagaactgg acaattggtt tgcggaaaat gaacagacag ataccactgt ttcaaagatc
    23101 tcttctaaca ccgagcatct tgtgctcgtt ttgaagaaaa caccaaaaat catttcttat
    23161 ctacgtgaat ggcagccaaa agcaaaaatc attggtttca aactattagt agatgtacca
    23221 aaggaatctc ttctggcagt cgcaaaaaat agtctgataa ataacaaaac tgattttatt
    23281 ttcgcaaatg atttgacgga aatccatggc gagacacacc acggctatct cttatctaaa
    23341 gatggaacag tggaagaagc tcaaagtaaa tctgagattg ctgcattgat tactgagaaa
    23401 attagactgg aggaatcaaa atgaaaaaga tcttactagg cgttactgga agtatttctg
    23461 cttacaaaag cgctgatctt acaagtcaat tcgtcaaatt aggtgcccag gtagatgtga
    23521 ttatgtctaa aagcagcaca cattttatca cgccattaac cttgcaatct ctgtcgaagc
    23581 gcgcagtcca tacagacgtc atgcaagaat caaatccgca ggtaatcaat catatcgaac
    23641 tagcaaaaca agctgacttg tttctcatcg cgcctgctac agcaaacatt atcggcaagc
    23701 tagcaaacgg cattgcagac gatcttcttt caacagtcgc aatggcgctt ccagtgggaa
    23761 caccaaaatt gattgcccct gccatgaaca cgaatatgta tcaaaacccg atcactcagc
    23821 gtaatctgga aacattgaga tctgtcggct atcaggaaat tgaaccaaga gaatctcttt
    23881 tagcttgtgg agattttgga aaaggtgcct tagctgatat tcagacgatc atcgaacagg
    23941 tcatgctgac tcttaatgaa agaaatgctt agaaaaaagg agtacttatg aaaaatacaa
    24001 aaaactttac attaactgcg atgtttttag ctattttgat tttattagct gttacgcctt
    24061 taggttttat ccctatcggt ccaatcaatg caacaaccat gcatattcct gtaatcattg
    24121 cttcgatcgt tttaggacca agactaggtg cttttcttgg cggtacattt ggactgatca
    24181 gcatgatccg tagcacagtt atccaaacac ctttgtcttt tgtcttttct ccgtttatcc
    24241 cagtcatcgg aacagaacat ggaagctgga aagccttgct gatcgcgttt attcctcgca
    24301 tcttgattgg ggtggttcct tatttcgttt ataaaggtct gcgcaaacta atgaaacaaa
    24361 aagcagattc cgtttcttta ttcttagctg gactttccgg ttcattgacc aatacgattt
    24421 tagtgatgaa tatgatctac tttttattcc agcaagatta tgccaaagtc atcggaacaa
    24481 atttaaatgc tgtttattca gctattctag cggttatttt tacaagtggt atacctgaag
    24541 gaatcgtcgc aggtcttgcg actgcagcag tatgcaatgt cttgttaaga tacttcaagc
    24601 acccttctct tactaactga tagtcatcgt agccgatctc tgattttttt ctcttttggt
    24661 gttactattg aatggaaaga tttgacgtcg aaaggatgat ccaaatgaaa atttttgttg
    24721 taggtgcaaa cggacaaatt ggccgacacc tgataaaaga tttagctcca agttcccatg
    24781 aaatttttgc aggggtgaga gatgttgctt cccaaacatt agtaaaaaaa gagaatgttt
    24841 cgtatgtctc ttttgattta acttggtccg tggaaaaaat gaccgaagca ttcaaaggca
    24901 tcgatgtatt gatttttgct gccggctctc aaggaaagaa tcttctgcaa gtagacttgg
    24961 atggcgcaat caaaacagtg atcgcagctg aaaatgcgca tgtctctcgc tatctgatgg
    25021 tcagtgctgt ttatgcagat gaaccagcaa aatggcctga gtccatgaca gattattata
    25081 ttactaaaca ttatgcagat gaatggctga aacgaactaa cttagatttt gtcattcttc
    25141 aaccagtcac attgactaac gatgaagaag ttacttccat tcaattaact aagcctaatg
    25201 agaaggcatc aaaaacgatc actcgctcta cagttgctgc tgtacttgcc gctctagtgg
    25261 aagaaacgga tatttctcgt acgactctag tactttctga aggtagcaaa gagttgaata
    25321 cagcattcca agaatgggca aaggaggaat agatccatgc gtgccatttc aatcaagcat
    25381 cctggttctg tagatgtatt agaacaaatt gaagtgcctg ttcctaaacc aaaacaaggc
    25441 gaattactga tcaaagtcca tacagcagct gtcaatcgaa cagatattat gaaaagagaa
    25501 tcagtctctt tgaaacctcc ctaccctatt ttgggagtcg aagtagctgg agaggtagtt
    25561 gagaataaaa gtgatatctc cacttttact cctgggacaa aagtatacgg attagtcaat
    25621 ctaggtggtt atgccgaata tgctgtgatg cctgccgatc gtgcaatcct tctccctgat
    25681 acgctagact atgtttctgc tgctggaatc tcagaagttt ttttgactgc ttatcaaaca
    25741 ctttactggc ttggaaaatt acaagaaggc gaaactgtct tgatccatgc aggagcaagt
    25801 ggtgtgggaa cagcagcgat ccaattagct agacagcttt ctcacgcgaa aatcatcgtt
    25861 actgcaggat cagaagaaaa actcgccttt tgtaaagaac ttggtgcaga tgaattgatc
    25921 aactataaaa aacaagactt tcaagaagag gtacgaaaaa tcactgaagg tcggggagtc
    25981 gatgttattt tggatttcat cggcgcttct tactgggaaa agaatttagc ttctatagcc
    26041 gttgatggac gttgggtctt gattggtatg ctaggtggga ccatcgtgcc tgagatagac
    26101 cttggtgtat tgattgggaa acgtgtccaa ctgcttggta cattattgac acctagaagt
    26161 gatcagtata aagcagagct cgcacaaact tttatgcaaa aagctgggcc ttttctagaa
    26221 aatggcaaga ttcggccaat cattgaccgt acattccaat tcagcgcagt caaacaagcg
    26281 catgaatata tggaagcaaa caaaaacatc ggaaaaatca ttttgaagat aactgaataa
    26341 aatcatgctg atcaaaaaag aggctgggac agaagcgttt aactccaaga aataagaaga
    26401 aattcacgaa aattgctttt caaatttttg tgaatttcag cttatttccg aaggaatttc
    26461 ttctgcttcc gccgtttata cgtgtttaga gcgtgagaca aaagtgttct ttacttttgt
    26521 cccacgctct ttttccgaat aaacggtgtt caaaagcttg catctgcggt aataagtcca
    26581 accaagttaa aaacataaga agctgttttt acttggctgt tcttattact tgatgcaggg
    26641 cagctttttc acaacctctt cactaaacag tgttcaatca gctgaccctc ggtattagct
    26701 caaaacgctg atttcacaac ctctttttat ttacgttcta tttcattcat tttccgaagc
    26761 aaatcgagct gcttgtatgc ccgcttgtcg cccaaaaata atgatctccg caactgaatt
    26821 tccaccgatc cggttgtttc catgtaagcc acctgtgact tcaccagcag catataaccc
    26881 cctaattggc tggttttctt tatctaatac ttcagtgttc gtattgattt tcacaccgcc
    26941 catcgtgtaa tggattcctg gtgcgatttt gatcgcataa taattcggag acgataagtc
    27001 atgttccatg gctgtggcac ggttgaattg agcatctttt ttctccgcaa catccgtatt
    27061 ccatccatca actgtttttg ctagtgtttc ttttggtaaa tcgatttttt ctgctaattc
    27121 ttccattgtc tttccagttg tgacatatcc tttttggtca taaaattcaa tagctgtggc
    27181 acgatcacgc acgccttggt caaaaatcaa ataagctgat ttttcaggca atgctgtaat
    27241 tgctgcagat actttatccc ttgtatccat ttcattgaca aatcttttcc cctcttgatc
    27301 gaccaagatt gctccttctc cgcgaacaac ctcaccaatc aagaccccct catcctgctg
    27361 cacagttgga tgaatttgta ttttatccat atcaacggtt tgtccaccta atttttcaat
    27421 catggtgata ccatctccag ttgatccttc ttgatttgtc gtaatataat cagctaaatc
    27481 gggacgatat ttttcaataa attctttgct ggcaccaaaa ccgcctgtgg taactacgat
    27541 tgcttttccg gtgacctctt ttggttcttc tccttgaaca tgtacagtca cttcattgac
    27601 cgtttcccca tttttcttaa tgtctgtcac atctgcgttg acaaaaatag ggatttcccg
    27661 ctcatggacg ttattcaata acccctccac taagtatcca ccaatagccg agccatcaga
    27721 cggacgatgt gtcctctttt cactcatccc tccagtgatc gttaagttgt ccagtttgat
    27781 accgttttga tctagccaat cgaccgcatc agcagagtga tcgacaaagt atcgaagcat
    27841 ttctttatca ttcgttcctc caccaccttt tagcgtttct tcatagaagg catcattcga
    27901 gtctttgatt ccttcttctt tttgaaattt tgtttctgaa gcattcatac cgcttgatga
    27961 tttagatgtg tttcctccgg caacaggcat cttttccaaa attactggat tcaacccagc
    28021 atcttttgct tcgatagctg ctgccatccc tgcaccacca gctccaataa tcacgacatc
    28081 ataagattct ttcatttctt ttggatctgt atatacttgt tcagaagcgc ctgatgatac
    28141 ttcggcagat tccttcgtac tagaacttgt ctgcgctgta tttttctgat ctgcgccgca
    28201 tgcgctcata gcaagaagtg caacggctgt taataaacca gcaactaatt ttttcatttg
    28261 tatccccctt ttctccttat actatattaa gtgatttttt tcacaatatc aactctgttt
    28321 ttctttaagt catatagctt tggtaaacac acgcttctta gtataattaa ggatatacat
    28381 gaaggagtta ttttatgaat catttgaaaa ccttttttac gaacagtaca aaaactgcag
    28441 gtagaatcac aaacggaatc tatattttat tacgtatcat cgtcgttatt atgctagtgg
    28501 atcaggtctg gaaccaacac tggggaaata caatgctttt attactgaca ttaattttat
    28561 ttgaaatccc ttattttctg gaaaagatat taaagataca gattccaaat atgctagaaa
    28621 tcattttgtt atcttttatt tttagttcaa cagttttagg agagttaagt gatttttatg
    28681 gctatttttc aatgtgggat acttttctac atgcattcag cggattttta gctgggggtg
    28741 tcggcttttc ccttgtttat ttgctcaata aaaatacaaa aaccatgaac ttgactcctt
    28801 tattactagc agttgtttcc ttctgttttt cgatgacagt tggtgttatg tgggagtttg
    28861 tggaattttc agcagataaa ttactgcaat tcgatatgca aaaagatacg atcatccagc
    28921 aaatcaatag tgtggagtta agtaaagacg gaaacactgt ctatcatgtt ccagatatca
    28981 ctcggacaat cattgaaagt caaaatgcag atggtaaaac agataaaaca atcatccaaa
    29041 atggttactt agacgtggga atcatggata ctatgaagga tttatttgtt aattttattg
    29101 gagcagttgt tttcagtgta tttggttacc tctatagtcg aaacgattac caaaaattta
    29161 cgttcatcaa gaattttatt cctaaaaaaa tcaaacgata aaacatgcta aaaaacaaga
    29221 gaaggggcag tgacaatact tttgtcactg ccccttcttt tttgaatgta tggcatgcca
    29281 ttagttatcc gatagtatta actcaaaaaa gtaagatatg aggaatgact atttcgtttt
    29341 ttatcccaat actgaggact tatttcacca tttcgttatt tatctaattt acttaaaacc
    29401 tgcataactt tttcataatc tggattaggt gtgccgtcta gattttcagc aataaaagta
    29461 aaacccattt ttttataaag agcaatcgcc tgatggctcc atgtctgtgt gtgaagatag
    29521 attggtccgt ccgtatggag ggtaggaaat tcttgcaaga ctctggcagt caatgctttt
    29581 gcgagccctt ttccttggta atctggtttc actgctaacc aatgaaaaac cggatacact
    29641 tgctctcttg atttttttcg ccaagcggta caggttgcta ctttttctcc tttttttgtc
    29701 tctacaaaaa acatccttct ttcaagttct tcaggataag gagcaaagtt ttgttgaaaa
    29761 tactcaagtg cttcatctgt cgtttgaaat tccccaacgg aagtctcaat ctccgcccaa
    29821 gcagattcat cttctttttg ataaaatcga aattcaaaac cttccgctaa aggcgtgatt
    29881 ggaacatttt gttgaagtgg tcttgtcatc cagatttctg cgtaaggtaa cgttttatct
    29941 aacatttttc tatccctcct cgtctccatt atgccaaata acatatgact cagctactta
    30001 tttgactata acagatagag atataaatca gaaccagtca tctgcgtcaa attcatttcg
    30061 attagcgtat acccatgttc ctgccatacc tcgcatgaaa tctcctaaag cagaagaagg
    30121 aatacctcca ccaggtgcgg gtgttcccgg actaggaagt ggtacttgcg gctgcagatg
    30181 ctcatcggtg gaatcaatag ttgacaagcg ttttttcttc gtttccttct ggtcatctga
    30241 ttccttctga tcttccgact gtttagcaac aaattctttt tctgattgtt gttttatttt
    30301 aggctctaaa atttcatttt ccaatccaga aacttgtggg gccaaatgag cttcttgcct
    30361 tatcgtttta ttagattctg agatttttct agatattctt gctaactcta ggcttcttgt
    30421 ttgttttact ttccctgttg gagaaactgc atgagccatt tgttgttttt tttctgacaa
    30481 gctttcttct tgtctttttt gttctttttg atctatctgt ttgtttaatg gtaaaacatg
    30541 taatagtgac tgagcatgga gttcttggag tgaatacggg tcatgataac tatacataat
    30601 cgtaaaatca cctgtttgtt tggtcaaata accatcctcc aatggtactt cattgattgt
    30661 aaccgataca tcctttaacg gtacgggttt acctaaggaa tttgttgctg attggatcaa
    30721 ctcttctttg tttatttttt cgtttggatg aacaataaga tcatgacctt ctaatgaacg
    30781 attgtctggt atataaacat aagtaaaggt aatttcccct cctgattgct tcctattatt
    30841 catcagttct gagtgaagta cttcaaggat ctccgaccag tgactttttc tgtctaatcc
    30901 gtttgcttgc atccaatcag aaatagaagt gactttccca ttttgttcat aagtcgataa
    30961 atctatattt ggcactcgat cagaaaattc agcaggtagg cgcaaatcag gaatacgatt
    31021 tacactactc atatgtgttt ctgcttgaag ttctttattt gtttgactat ctataaaatg
    31081 agtgatgaca gtcgatgaag cagcagatgc ttctacataa actacagctg ttgtttctgc
    31141 cacatttgat gttttcgagt ctatataagt taatacaacg ggatattctc ccggagttgt
    31201 agtatctact gtcccgttca ttttgatttc ttctttattt cctgaagttc catcgctttt
    31261 tgttacatat tcaacaagat ctttaggggc gtaactctct cctgttctta agtgaagatc
    31321 ttttcctttg atagctgttt gatcagcacg aacatggatc acagcagatg cagtcattgt
    31381 ttttaaagca attggatcaa aataggacaa ggaaatagta gatgttcctg tattagtcgt
    31441 atccacgata ttcccattgt ttgaaattac tttggacata tctccttgtg ttccatctgc
    31501 gttcttcagc ctttctacca gatcagatat cgaaactttt gtccctgcca gaacatcgat
    31561 tttctttctt tcaaactgtg aataatcttt ttcatataca taagaaactt gtgcgcttcc
    31621 accgtccttt atatctgtca aagcatgatt caaaatatca gtgatctgtt ttaactgatc
    31681 accttttgta ggatcagtca tatcggaaaa gatagaaagc ggcacactgc ttccggtttc
    31741 cgatgtccat aatgttttgt taggaattaa ccagtagtgg tttatcgttg gaggataact
    31801 gactttatta taggaagtca atgcaggaag tagctgtttt ccatttgcat cagtgaaagt
    31861 atgagtaata gtgatagggg aatcagtggt ctcagaaaca gaggtacgta cgaccttgat
    31921 ggtttgtgtc gttgcctgaa cgggtacatg catatagaca cctacagata aactgatcag
    31981 catcgtgcgc atcataaact taacgtagtg tttttcagaa cacgaccgtt ccttatctaa
    32041 acgacaagcg tgtttattta gttgttttga acgtcttttt gaacacattt attcttagtc
    32101 ctccctactc ttgtctaaac atgaagtagt aattttcata agatgatttc attatataaa
    32161 taaaatcaaa agaagatgga ctattaggag agtatttttt ttgatttttt attgtttcaa
    32221 gaaaatcgga ataataactt atgtactttt taattttgtt aagtaatata tctagttata
    32281 tctagttata tctagttacc ttttctttga aaaaaacata aatcagctaa taaatatgtg
    32341 agacaaagct gccatccata aatactagct gattttttca gttaaatgtc tatttttttc
    32401 tctgatgatg gtatttccaa aatattccca gtcatctgga gtcggtggat ttttccaaat
    32461 tatctgttct ttattaaatt tttcaagtaa acaatcagat aaataaatat tcgtacgaga
    32521 agtgattcga ctctcaatca caatattgta atttttaaat cctttcactt gagaaataat
    32581 gtaatcggta taagcagatc cttgcgaaaa atcaatacag acatgaatcg gtgcttcaaa
    32641 atatgatacc ggacaaatac cgaccaataa aaagagataa tcataaaata agcgaatcat
    32701 gaaacgttca tcttttccca agaaatagcg tttattctct tgtatgacct tttggattgc
    32761 tgtactgaat attggatacg tctcgaagaa aaactgtagc tgctttttag acgtaaagct
    32821 agtcatctca aagtcgaata tccaattttt tcgattgaca tgcatcatac ccatacgaag
    32881 ttcttttcgt atatatagtc tttcttcttc agagatttca atcgaaaatg gtaattgatc
    32941 aatcaattcc actgacattt tttgactaat catgtggata tcatgaaaat gagcttccgc
    33001 aagtccaaat gcgccatcta attcaaattc ttcttccgtg atcaaaaaca acatgatata
    33061 agaaatctca tcaatgatct gctctttagg gatatgaaga aaagaaatat gtgataaatc
    33121 cttgatgatc ttcattcctt ctgagctctt aaagtattca tctgaaaaga aacgttttcc
    33181 gattggttga ttcccatagg ccctcaacaa actaatagtg gttagcaaat tgaatttgat
    33241 tcgttttgtt gcagacagtt ttaaattgaa cagatattca aaatattgca cgatactctt
    33301 tgcttcattc atgacgcttt ctctaaatgg catagaaaaa ccattaaaga ccccgaaata
    33361 taccccaaat aatacgttcc gtatgtttat ttcttcccca actaatatgt ttttctttaa
    33421 ctttatttga tgctgttcaa gaaaagagac taattctctt ctttttacat aggctcttga
    33481 tatgcttaaa aaatgattct ctgcaaattt ttcgatcgtt acttttgaat ccacgatctc
    33541 cgttaacagt cgagcaattt ttgatcgttg aaagtagatt cttcttaaat ttttgatatc
    33601 cgtcaaattc agacgttcga catggatctc tgcttcttct gaaatttgga tctctggctt
    33661 tgttttgaat tcagtaaatt ctttatttaa ttctatgata taatttcttg ttttaaattt
    33721 agacaaacct aatgtttcat ataacttagg cagcactaca taattctttt tctcaaattc
    33781 taaatatcta gctagcagca gtttttctct atcttcctct tctataaggt aatccaactt
    33841 catatcctac acctcaaaaa atgcctcata ccaattactt gatatgcaga tgaaagttca
    33901 tcttttcacc tatactgatt ttatgatgga ttatgcttgt tttttcatca gttattctca
    33961 ttttttatct tttttttgag aatattgcaa aaaatggaaa aatttatgag gaaatattct
    34021 atattttttg ttttattgtg ttaaaatgta caagatttgc gccatttgcg taaacaacca
    34081 caaaaaagag caggacggcc accgtcctgc tcttttactt attttaagtt ccattactta
    34141 ttaattggct aaacttctgc ttgtttctga tattgcttgt ttttctccaa tgatccgcac
    34201 ttctgtttct aaagacacat caaatttttc tttgattact tcttggatgt gcgcaatcaa
    34261 ttcaatataa tctgtcgctg tcgcatgatc gatattgacg atgaatccag catgtttttc
    34321 agagacttgt gcaccgcccc atttcaggcc ttgcaatcct gcttgttgga tcagctgacc
    34381 tgtatagtgt cctactgggc gcttaaagac acttccgcat gaagggtatt ctaatggctg
    34441 ttttgattga cgcaattcgg tcaactcatc cattcttgct ttgattgctt cataatcccc
    34501 tgtttgcaaa ctgaatcgag cttccaatac gatagcacgt aattcttgga ctttactgtg
    34561 acgataagaa aataccattt cgtcttttgt caaagttttc aatgttccat cttcaagcaa
    34621 aagatccact tcagcaaaaa catctttgat ctctccgcca tacgcacctg cattcatata
    34681 aaccgctcca ccgacacttc ccgggatgcc gcaagcaaat tcaaatccag tcaatgattc
    34741 tgccaaagct gcataagtcg tatcaatcag tgaggcacct gcttccgcaa tgaccatcgt
    34801 tcctttgaca tgaatctgtt tcatttcagt cagcatgatg actacaccgc gaatcccgcc
    34861 atcttgaacg atcagattgc ttgcatttcc taataccatc caaggtatat catggattcg
    34921 gcaataatcg atgatttgct ttacttcttc ttgttttttc gggaatgcaa ggacatcagc
    34981 tggtccacct gttttcgtaa acgtatagtt catcaatggt tcatcaaaca atatagtaat
    35041 cgtggctaag ctttcaacta tttcttcttt attcactgag gattttcctt tcttttctca
    35101 aacgtcctca ttattctatc acgcttaata caatcttgcc agtcttgttc aaagttgatg
    35161 acggtagtga tctttaagca cttcctcaca taattcatga cttcttacaa cttctttttg
    35221 tttaagcaat tctgtttccg atttacctaa acggatctga gaaaagaagg cctctaccat
    35281 tggctcaaac ccgcgtttga ctagcgtgtt tgtccagtcg ccaaattctt tcactttttt
    35341 tccatcagca tcttgaatga caagctgggt cagatcgttt acttcataag taccattttt
    35401 acttgttact tgatattttt ctatattagc gccacttgct aaatccatcg ttaaaatagc
    35461 cgtttgattt tgtgtttcta attgtaaaat ggcatattcc aaaaattcct ttgtttctct
    35521 tatctggtat tttgttctca aaatgggttc atctaataaa tacacagctg tatcaataag
    35581 atgtaaaaac aaatcataaa ggacgaactc tgtcgtttct tttgccgcta ttcgattttt
    35641 ttgcaggtgg atcaaccgct tatctgggat acgtttcaat tcttctacca taggagcaaa
    35701 gcgccggttg aaaccgatca tcaaaattat ttggttctta tcagctaatt cttgcaattc
    35761 acgaacttca tttagatgga cactcagtgg tttgtcaata taaacatgga taccattttc
    35821 tagacatttt ttggctaatt cataatgtac ttttgttgct gcgtggatca tacatgcttc
    35881 gattttttct tctaaaagct catcgatcgt ttcatataga tgttggaacc cgtactcttt
    35941 ttgaattctt tcttttgttt ctttatttct tgttgcaaaa taaaaatcaa gtgttccttg
    36001 ttttttcgca taagttggta aatatgcttt ttctgcgata ttccctacac cgattacacc
    36061 aatcttcatc tactttcctc ctggatcatt tagttacttt catcttacac cattttttac
    36121 taaaatgagg tacaatagta tcgcaaaggt aaggaaatta attcgaagga gtgtgctttt
    36181 attgaaattt atctcttgga acgtaaacgg gcttcgtgcc atcgtaaata aaaatttttt
    36241 agaagttttt catgagttag acgccgattt tttctgtctg caggaaacga aactccaagc
    36301 aggacaaatt gatttagatc ttccaggtta ttatcaatat tggaattacg cggaacgaaa
    36361 aggctattcc ggcacagcga tttttgctaa aaaaccagca ttgaatgcca cttacggaat
    36421 gggtatcgat atccatgata cagaaggccg tctgattact ttggaatatt ccgatttctt
    36481 tcttgtaacc tgttacacgc caaattctca aagcgaatta aaacgtttag attaccgatt
    36541 agaatgggaa gaagcctttt ataattattt ggaaaatcta aaaaaacaaa aaccagtcat
    36601 cgtgtgtggg gatctaaatg tcgctcatca aaagattgat ttgaaaaact ggaaaacgaa
    36661 tcaaaaaaat gctggattca ctccagaaga aagagcggct ctttctcgac tgttggataa
    36721 cgggtttatc gatacattcc gttattttta tccaacccag gaaggtgtct actcttggtg
    36781 gaactaccga ttcaattcaa ggaaaaacaa tgctggttgg cggatcgatt actttttgac
    36841 gagcaaagat ttagagccag gactagctga tgcaaagatc catacggaca ttatgggcag
    36901 tgatcattgt ccagtagaat tagatttgaa ataaagaggt tgtgaaaaag tcgtttagtt
    36961 tcgagtatta agaaaaattt tgtgaaaatg gctttccaca ttttgcataa atttggcata
    37021 ataccgagaa actggctttt gaacactgtt tatcgagaga ttgtgaaaaa gctgtcctgc
    37081 atcaagtaat aagaacagcc aaacaaaaat agttcctcat atttttcgtt tggttgggct
    37141 tattaccgca gatacaagct tttgaacacc gtttattaag aggttgtgaa aaagctgcac
    37201 tgcatcaagt aataagaaca gccaaacaaa aatagttcct catatttttc gtttggttgg
    37261 gcttattacc gcagatgcaa gcttttgaac accgtttatt aagaggttgt gaaaaagctg
    37321 cactgcatca agtaataaga acagccaaac aaaaatagtt cctcatattt ttcgtttggt
    37381 tggacttatt accgcagatg caagcttttg aacaccgttt attgagaagt tgtgaaatca
    37441 gcgtcctgac ctgagtatta gagaaacaaa tggcaaaata gttcctcata ttttgctatt
    37501 ttttgagcta ataccgaggg tcagctgatt gaacaccgtt tagtggagaa gttgtgaaaa
    37561 agtcgcctac tttcgagtcg taagaaattt ttttgaaaat ggttcctcac aactttgcat
    37621 aaatttgact taataccgag aagtcatgat ccccatctaa ctccaaatca caaggaatga
    37681 gttcaaaaac tagcttttct caacaaatat tacataaaaa attctatgtt ttttgttaaa
    37741 tttatttgct tttttcaaaa gtatgttaca gtaatttccc aaggaggttt tacagaaatg
    37801 aattttgttg ccatggattt tgaaactgcc aatcatcagc cttatagtgc ttgttctctt
    37861 gcgctagtca tggtaaaaaa tagccagatc gttgatgaat tctatacatt gatacagcct
    37921 gagactcctt ttttctggcg aaatgtccaa attcacggaa tccatcaaga agacgtacgc
    37981 aatgcgccga aattcccaga agtctggcaa actatccaac catattttca aaaaaatcgt
    38041 ttagtcgttg cacataatgc tgcttttgat acaaaggtct tagcgggatg cttagattat
    38101 tatcatcttg aacagcctaa ttatctttct ttatgtacag tgaaaagtag ccgtcgcctg
    38161 tttcctgaat ttccaaatca tcgattgaac actgtgtgcg aaaatttgaa catccaatta
    38221 gatcatcacc atgatgcatt ggaagatagt cgtgcatgtg cggaaatcct gctttatcaa
    38281 gaaaaaaaat tcgggacaga tccattgaaa aaacttgtga ctataaagta aaagaatact
    38341 tatgaaacac acaaagaggt cgtgagcctg ccgtttcact ccgagtcaca aggagcaatt
    38401 tcaaaaaata gcttctcatg tttattaaat attgtgactg gtgaccgagg agctggcagg
    38461 agaacaccgt ttattggaga ggttgtgaaa aagctgttct gcatcaagta ataagaacag
    38521 ccaaacaaaa atagcttctc atatttttca tttggttgga cttattaccg cagatgcaag
    38581 cttttggaca ccgtttacca agaggttgtg aaatcagcgt tttgacctga gtattagaga
    38641 aacaaacggc aaaatagttc ctcatatttt gccgtttttt gagctaatac cgaaggtcag
    38701 ctgattgaac accgtttatt caaaaaaaat ggactgcgac acgacttttg tcacagtccc
    38761 ttcgtgtgtt tttctgcctt ctcaaaagga tgacagtttc tcactctttt cctatttctt
    38821 ctattcaatc aaataactca ttttatatac atctaaaaat tcacctagat ctgttcttgc
    38881 ccctctaggc atgaccgctt cgatttggaa gcccattttt cggtaaaggt gtacggctct
    38941 ttcattacga acttgaacgt caagctccaa tcgaaaaagt acacccattt ccttcgccca
    39001 actgatgatt tcttctagca taagagtgcc tagtcccatt ccccaatatt cctgcagaat
    39061 actgataccg acttctccca cgtgagacaa acgaaattga ctgtctgcct tgacagatgc
    39121 tgttccaata atcgtccctt catagattgc aagcagcaat aaattattat tgctttcgta
    39181 tatataatcc aactcttctt ctaaggtttc tggtggtaac aggagttctg cttcatccaa
    39241 aactaaaaat tctgtctcct tattaacttg tcccatcatc aaaagaatgt cttttgcatc
    39301 tcctggcact gcttcccgca agatgatccc aacttcttca ctcatgattt tcagcccatt
    39361 tttctagaat tcgctgtttg aaggtttcac tttgctcccc gtatgagatt agtttcacat
    39421 accgcttttc taaatctgta tcactttttt ctaaaatcag ttccaaataa tcctccggca
    39481 gtgcttcttc taatagattt ccccattcaa caacggaaag cccatcacct tcaaaatatt
    39541 catctaaccc taaatctgct ccgctagctg ctacccgata aatatccata tgatacaacg
    39601 gaatccgacc ttgactatat tctctaataa tcgtgtatgt cggacttttg atcatttgcg
    39661 ttatccctaa tccttgggca attcctttcg tcaacgttgt tttacccgca cctagatcac
    39721 cagtcaatat cagattgtca cctggcattg cggaatgacc aattgcctct gcgaattgtt
    39781 ctgtcattgt taatcctgat agttcgatca tttttcatct tctcccgctc ttctttcttt
    39841 ttgccagtat atcgcgtaat gaagtttttt taaagaaaaa atgaactagt caagaacagc
    39901 agctgctgtt tttggctagt tcgcgtgtat ttgttaatca atcaatgttt gtgctgctgt
    39961 gataatcgat aatttatata catcttcttc atttgctcca cgagacaaat cagaaaccgg
    40021 tttgttcaag ccttgtagaa ttggtccgat tgcttcaaag ttaccgaaac gctgagcaat
    40081 tttatagccg atatttcctg actgcaattc tggaaataca aagactgttg cttgaccagc
    40141 tacttctgaa tctggcgctt tcagttgtgc aactgaagga acataagaag catcaaattg
    40201 caattcgccg tcgatcatgt attgtggcgc tagtttttta gcgattttag ttgcttcaac
    40261 tactttgtct acttctggcg atttcgctga gccttttgtc gagaagctca tcattgctac
    40321 ttttggttcg atatcgaaca attctgctgt ttttgcagaa tctacggcga tttcagccaa
    40381 ttcttgcgca gttggattca cgttgatcgc acaatccgaa aagacatatt tttcttgatc
    40441 tcttccacgt accatgatca tcgctccgct tgtccgactg atgccaggct ttgttttgat
    40501 gatctgaagt gctgggcgaa cagtgtcgcc agtcgaatgg atcgctccag agaccattcc
    40561 gtctgcaatc cccatatacg taagcatcgt accaaagtaa ttcacatctt ttaaaatctt
    40621 ttctgcttgt tctttggatg cctttccatt tctacgttca acaaaagtat ccaccatttc
    40681 atcccactta tcgtaattat cagggctgat gatcgtaaag ctagatgttt tgattcctct
    40741 ggcatgcgct gcatttctta tttcttcttc gttccctact aaaatgggtt ccacaagttc
    40801 ttctgctttc aaccgggcag ctgcgcctaa aatacgagca tcagtagctt ccgggaaaac
    40861 gattttgatc ccacggcgaa caattttaaa tcttaaacta tcaaacaatt ccacaagatg
    40921 acctccagac gtttttatat gtattatcat acactattcc agaaaaaaag aacagtttat
    40981 tttatctgta tcagtcaaaa atgctggaaa aattaagttt ttcacataca aagcgaactg
    41041 cactataaca ggaaagcgct gttttattac actgtttcag gcagttgcca atcaatcggt
    41101 tcttctccta acgcaaggag cgcatcattc gttttcgaga agggtttgga accaaaaaag
    41161 ccacgacttg cagataacgg actgggatgt ggagatgtta tgatgatatg gcgactctta
    41221 tcgatcattt tgattttttc ttgtgccggt tttccccaca agataaacac gattggtttt
    41281 tcccgttcat ttaatttttc aatgatcgtg tctgttaatc tttcccaacc tttcccgcga
    41341 tgagaatacg cttgcccttc ccgaacggta agaacggtgt tgagtaaaag gactccctgt
    41401 ttagcccatg acactagatt tccatgttga acaggtgcga ttccaagatc atcataaagc
    41461 tctttataga tatttcttaa cgatggcggg atctttacgc caggttgcac agaaaaagat
    41521 aagccatgag cttgattttc tccatgataa ggatcttgtc ctaaaatcac cactttaact
    41581 tcttcataag gagtcaattc caatgcttca tagatatgat acatatctgg atggatcttt
    41641 tgggacgcat attctttttt taaaaattct cttagatgca gataataatc ttttgaaaat
    41701 tctgaggaca aaacttcttg ccaactgtta tgaatgattt ctttcaaaaa ctccacctcc
    41761 taataaaaag aataactcac attttcttca atcacaaggg acaatcttca ccctcagcac
    41821 ttgattaata tggtaaacta ggaacaagaa gcagaaagga acgataatca ttatgatcaa
    41881 attaattgca tcagatatgg acggcacatt attagatgcc catatgagtg tttctcctga
    41941 aaatgccgag gcgatacgtt ttgcaaatga tgccggtgtt gagttcatgg tcgctactgg
    42001 tcgaaactat caagaagctc gcgcagcttt agatgaggta ggaatcgatt gtgcgatgat
    42061 cactttgaac ggggcacagg tatttgataa agaaggaaat tcattgttta ccgtgtcgat
    42121 tccaaataat caagcaatct ctgttttaga tattctagat gctaacggta tttactatga
    42181 agtagcaacc aacgatggtc tttattctga aaatcaagcg aaacgaattg aaagttttgc
    42241 ttccatggtg gctacccatt tacctcacct tacgtataaa atggcgattg ccatggcctc
    42301 agctaagctg gagttattgc acatcacata cgtggacagt attcgtgcta ttttggaaga
    42361 aaagaatctg gaagttttaa aaattatttg ttttcataca gaagggccag ctgtattagg
    42421 tccagttgga aagcagattt ctcttttagg cgatctagcc gttacttcct ctggtcaaaa
    42481 caatatcgaa gtgaaccata aaaacgctca aaaaggaatt gctgttgccc atgtcgctca
    42541 cgagcgtggg atttctttag aagaagtcat gacgattggc gataacttca atgatgtcag
    42601 catgctgcaa gtagcaggag tcagtttcgc aatgggaaat gcagaaatcg aagtaaaaga
    42661 ttatgccaaa tatacaacgg acacaaacct tgaatctggc gtaggaaaag ccatattgcg
    42721 cgcgattgca gaagacttgt agttttatct agaaaagagg gatatagatg tcagaatttt
    42781 tcattcagga aaagcagctt ggacgtgcaa ctcggacaat tgtcaaaaac gaaaaaggac
    42841 attccctgtt tttgatggtt ggtcgctggg gaacaaaggg cgatgcattg tctctttatg
    42901 ccatgaatgg cgatctcgtt gctcacatca agcagataag cctgacattc ggtacgcgtt
    42961 ttgagctgta taaagagttc gaaaaggtgg gaaccatgca gaaaatattc aattggcccg
    43021 gtgactttta ttatattcgt agacttcact ggacagtcca aggtgatatc tataatcatc
    43081 aatatcaaat ccatcatttc aatcagcaaa tcatgaaaat ggataaagca acactttttt
    43141 caggagatta ctatgtattg gatgtctcaa atgatgaaga tgctccagtt tgtatttgta
    43201 ttgctgcggt tttagattac tggctctacc gtaaagacaa aagtcgcgat aagcctgttt
    43261 cttaccgact taacttaagt taaaaagatg tacctgaaat gcggaaatac gcatttcagg
    43321 tacatctttt tagatattct tttgcatatg atcataaaga tgaccactga tcatccgctg
    43381 accgacaact ttgaagtcat ggcgttcgta taatttttta gcctttggat ttttttcatc
    43441 cacacttaga ccgatgacgg agcgattagc tttcttcgcc aatttaggta atgcttctaa
    43501 taatcgcgaa ccgatgcctt gtcctctaaa atcttctgat acactgatag agtccaaata
    43561 ccattcgttg ggaaacgttt ctttatcaat gaacaaacgt gtagacgcat ctagctgata
    43621 tttctctaag ataggtacca gtggctgatc gatgattgat tcttcttcat ctgtataacc
    43681 gtaagcaact cctgcaactt taccgtctat ttcttctacg atacctcgtg aataactgta
    43741 acgataattt ggatcagtga ttgcttcttc taaaatctct aaagtctttt gttcccctgt
    43801 ctgcttcaaa aatggcagtt ccatatcttt tagaatcact aagatcaatg gggcgatttc
    43861 tggagcatct tcttttctcg caaaacgaat catagtttcc tctccttttc tccattctaa
    43921 catgcagaaa aagaaatcgc aaaatcgtta ttttaaaaaa tcttcaatct tttcagtaat
    43981 gaaataacca tgagtaacga ttcttgccgc ttcagttcgg caataagggc agacgactgg
    44041 catttcttta tcattatgtt cgactacatt attgacttct tcgtatgcaa atttttttcc
    44101 gcaattaggg catttcattt tttccatgtt atctcaactt cctttcatct ttactctctt
    44161 agcttactct tatattgtaa aaaagagaag caatatcctt cttctatgca gatatccata
    44221 cctgacggtc ctgttctcca tctattaatc ggactttata ataaggacgt tcatctttga
    44281 ctagaagtgt ccactctttc acttttgctt ttttcccgta gtagctgact gcttccttca
    44341 tcgctgcttg cggttgtttg aactcttccg ttttttctat atcaaaaaga tgttctgcgg
    44401 ccttttccgt gtcatttcgt acggttgttt tcccagtgga tggattgact gctatgactt
    44461 gtccttcaca aaaaaactgg tattcatatg ttgcattcgt aggattctcc aaatcttttt
    44521 caactgcaaa atgaatagca gatatgttat gttcttttgt ttcgtttttt acgattgctg
    44581 ctgctttttt caatgagatc cgatattcct ggtcactaat atcatccatg tgaaaagcgg
    44641 cattgagcag tcccgtcata ccggtaatcc ctattacgat gagggcagca acaccaaaca
    44701 tcattttttt cattcttcat tctcctgttt ctttttttta aagaatatca agaaatgaac
    44761 gaatgaaaaa tcgaatgaaa cgaaaaaaaa gtgacaattt tgttatcttt attcgtgcag
    44821 ttctaatggc aatccgtctg gatcaaagaa aaacgtcatt ttttttcctg taaaggtatc
    44881 ttctctaatc ggttctgatt cgatccctaa ggactgcaat tctgcaattg tttcttcaat
    44941 atcgtctact ttgaaagcaa gatgacgcaa gccacaagct tctggatagt ttggtcgttg
    45001 tggcgcatta gcaattccaa aaatctccaa ttcagcactt cctagtttca gatctaattt
    45061 atagtcatct cgttctttgc ggtaattttc tctgattact tcaaatccta atttattaac
    45121 ataaaaatca cgtgatttct gataatctga aacaatgatg gctatatgat ggatcgttgt
    45181 aaggttcata tgagcactcc tattcttcgt ttaagctcgg atctatatta atctccagtt
    45241 ccattgtaaa tgtgtcagat tgaaaaaaat agctgttttt cctttttata agaaaaaagg
    45301 caaaaaaaca gaaagtaggt cctccaagac actcttcctg ttcccaatat aataaatgaa
    45361 agtaagaaat tatattttca agaaaacaaa cagaaaatta tcataacaca aattatttat
    45421 aattgaaaga ctagtttttt ttcaagaaaa gcatacaata gattgtgtta gtaaatacag
    45481 aacacactac atttagtgtc ttaaggagtc ctcatacatg aagtcatatt ttcagttttt
    45541 agctcatcag ctaaaaggct ggccgcaaca aaattattat cttttctttt tcagtcttgg
    45601 ctgccaggtc atgactcttg tcaatagtcc catcacttgg ctgtccgtta ttacatttat
    45661 cggtaccacg cttggtgtat tgtgtatttt atccatcaat gcggcaaaat cagtcaacgg
    45721 tattttaggt attttgtctg cgatttgttt tattatcgtt gggttttcag caaagaacta
    45781 tttaagtatc ggtgaacaga ttgcttatat gatcacattg gatatccccg tattgttaag
    45841 taaagaatgg aatcataata tggcttcaaa aatccgaaaa ttcactggaa aaagctggtt
    45901 tatcgcaatc atcagtactt tccttgtcta tcttgtttca ggattcctga ttggtcgtta
    45961 tacagatgat cctcggccgt gggtagatgc cattgctttt tctattagct tgactgctgg
    46021 tatcatcagt ttcttgcgtt acaacaacca atattactgg tggttagctt cagggcttgc
    46081 tcaaatggtc ctttggtata tttcatttac gcatggatct gcaagtttgg cgatgttcgt
    46141 gaacagctct gtttacttgc tgaatgatgt ccttgcattt accgtttcac cttggtataa
    46201 ccaaaaagaa cgtgaacgta tgcaaaaaat ggaagaagaa tactacaacg cacaacaaca
    46261 cgcataaaaa aactgagcgt gggacaaaag taaagaacac ttttgtctca cgctctaaac
    46321 acgtataaac ggcggaatca gaagcaactc cttcggaaat aagctgaaat tcacaaaaat
    46381 ttgaaaagca attttcgtga atttcttctt atttcttgga gttaaacgct tctgtcccag
    46441 cctctatttt ttatagtaat tccttcagat actttcttgc ctcatcattg aaacgcagtg
    46501 attcttctaa cttctgataa tattccaacg cttgtttctg agcttcagta aaacgataat
    46561 gttttccttt ccatttgtcg attgtctctt gcacatttcc agattggata tctttcacta
    46621 ctagttgcca tttttctttt gagactgtac ggtctttctt atcagcagat tgtatagctt
    46681 ctcgttcttt acgcaatact tttaaaaaac catttctgac tatccgagga atgctgtcga
    46741 agaacccttc tgtaaaacca tagcgacaat attgcttcca aataaataga tagatttttg
    46801 gttggatgaa tcgttggttt ttcgcaaaat attccatctg agcagtgact tctggtgttc
    46861 gttgacgttt tgtctttctc aacacggaaa taaatgtttc aaaataagca ttaggatgta
    46921 ctggcacttc ttcatatacg atggattgcc aatctttacg taaaaatgcg cgatagttga
    46981 tcaagaattc ttctacatcc tttactaatt cttctgcaaa gtcgtcaaat agttcttttt
    47041 ttatctgtcg cttttttgac tgcccattga tgtgttcact tattttcttg atttcatttt
    47101 ccaatgcttg ataatccgct atgtaaatcg gcatttctac ttggcgaaat tctgcgagcc
    47161 gctgagctaa ttttatatcc ggtaaatatg gctgtttcat ccgacgattt tggtacaaga
    47221 caaaacagta tttttgccat agtccttcag gaaaatcgat attcttctgc ttaagccata
    47281 ataattcgtc taaggccaga tcaacttttg tcattccctg atggatcgaa gctgccactg
    47341 tcggagagac atgcaggtga tcggcaaagt ggttgatgcc tagttttagg atctttccgg
    47401 tttttggcga tttaacgatg tattgcactt ttaattctct accacactca caatacaatt
    47461 tttgctggct tcgttttgtt cgaaaaaacg gattgatctt gaagtcagaa aacacccaat
    47521 ctgttgcagc taaataatgt tcttccataa aacgagagct gattagatat cggcggtgct
    47581 tatcgactag ttcccgctgt tttttcgtta attttgcata gatctcccaa cgttgactgc
    47641 ttgtgtattg tttagaaatt ttgatgggat agcttttgct gatttctttt ggaaaccatt
    47701 cttcaaagac ggattgccat tcttccacgg ctgtttcttt cctttctaat tacaaaaagc
    47761 tggctactaa cataacgtta gcaaccagcc agtgtttctt gctaaattag tgagttgttc
    47821 cggcatttcc ggaaatatct tctttatttt ctactgctgc ttcaactgca taagtcaaag
    47881 aagaagcaat gtcttctaaa gacatagaag gcgtacccac tggacgatcg atcacttgat
    47941 cgggtgagaa tggcacgtgg atgaacccac ctcgaattgc cgggaattgt gtttcgatca
    48001 aatgaagcaa acgatacatg atatcattgc agacaaatgt tcctgctgta taagagatgt
    48061 acgctggtag accatgatct tgtacatttt ttgtcattgc tttgattggc aatgaggtaa
    48121 agtaagcggc tggaccgttt tcttctaaag ccgtatcgaa tggctgattt ccttcattat
    48181 cagggattct tgcttctgct agattgattg cgacacgttc gaacgagact gctgaccgcc
    48241 cacctgcttg tccgacacag atcacgacat ctggttggtg ctgttggatg gcttctttga
    48301 ctacttgact gcttttttcg aatacggtcg gtacttccac tttgatgatt tcagcaccgc
    48361 tgatttcatc tggcattttt tttactgctt cataggctgg attcactttg tccccaccaa
    48421 atggatcaaa acctgttact agtactttca tctgttgttc ctccgtccga ttgatttaac
    48481 atatggttat cttttatcat accattttcc ttgaacagcg taaataaagg aaacaatagt
    48541 ttaaataaca taacagatca aacttaatat attcttataa aaaaatagtg ttccactaca
    48601 atgttagaag aggttgcgac aattattctg tcacaacccc tctcttctat tatttaaata
    48661 gaatcatata agcaatttgg aaaactagca taaataacgc aataaacaac tggtttttga
    48721 tcactccgta tttgtctttc atctccagca tcgctacagg cacgatattg aagttagcag
    48781 ccatcggtgt cagcagggtc ccacaaaaac cgcaagtcaa tgcaaccatt cctattaacg
    48841 ctggattcgc tccatgacta aatacgaatg gtgcaccgat cccaaccgtc atcacggtga
    48901 tggccgcaaa tgcattcccc atgattaccg taaatatcac catgccaaga gcgtaaatga
    48961 tgatgccgat gttcacattt ccttctggaa cgatcgtacc tactgcattg gaaatcactg
    49021 tcccaactcc agcgcttgta aataccgcac ctagagaagc taaaagcatt ggcaacatgc
    49081 ttaacggccc tactgtgccc agcatatctg ctgcatcatc taaaaatgta cttggtcgat
    49141 tatctcgaga aaagaacatc aagattagca tggctgcaaa aacaccgacg cccacgccga
    49201 ctaaagcacc taaattggta aatagagcaa acaagatcgc aaagacaccg atactcaaag
    49261 ctggaataaa aattttcatt cctagtttgt ctgacatttt ttccatatat tcttttgatg
    49321 gaagccggct ttctcctttg ctgactttct tagcaattgc tggtatggtc atcgcaaaga
    49381 tcaagccacc gttcacgatt gccggaagcc atcttcctcc tgcaataact acccctaaga
    49441 ccgtccagaa aaaggctgac ccataacgat gaggattggt tttatctgtt aaatttctta
    49501 ctccagtgta aatcaatacg agtcccatca cgatataaag gatctccagt aatttatcgc
    49561 ctaataaaat atcaggattt gtaaaaaagt ccatcttatt gcccctttcc tggataatat
    49621 ttcttcgcta atttcttttc tttaagatag aagtagacac ttgccacaac taaagccgtg
    49681 atagccactg gaacttccac taaagcaagc tgtcccaatg ttacgtcata tcctagatct
    49741 ttcagtgttg attggactag caacgcccct gctcctccga tgaatagtac ttggccaaag
    49801 aaccagcaga cattttccat agctgaagcc atacctttta gttcttcttc atgcttagga
    49861 tggacttcta acccttttga ttcgatggtc cccaatgcca tcggtaaaat gattggacga
    49921 acaaatccag caactccacc aaaactcacg ttaaaagccg caaagatcat tcgaaagatc
    49981 ccataaatat ctacaatcat accagcagat actttcttga atcgcttgat caaggaagcc
    50041 gctgattctt tcagaccatt tctttcaagc gttcctgttg ccaacataat gatgataaaa
    50101 atcgccatcc cgcgattgtt tacaaaactt gtacctaaaa gttctaacat tccttgaatg
    50161 ccaagaccgc cagtcaaagc tgtaacaact aaagcaacca ttacgatcaa tatcgagtct
    50221 aatttaaatg caaacccgag aataacaatc aagacgccta aaaggctaag ataattttcc
    50281 atatattttc ctccataaaa tgacaatatt tttttaatta taaagcaaaa cacataaaaa
    50341 atatagttgt tttctcacga aatagacact atttttaaat atttttcgtt atttttttat
    50401 cacaaaaatt atcttactta ttgtaaggta aagctttttt taatttattg cccgataata
    50461 tatagaaata aggtctagtt actgtttttt ttaaatgatt aataaataac aacttctttc
    50521 tatgaaattg caaagcattc atcttctttt ccgctaacga tatatccgtc agtgcttggt
    50581 acactttact aaaaagtatg agattgccga tatctggata ggtgtgctat actacagaaa
    50641 aagatataca atctgccacc gggtaggata aagaggatga tcattccatt aggtctttga
    50701 agggatgatt ttcctctttt tgtgtatttt tttatagtta aggaggaatg taagtatggc
    50761 atggatggaa ttaatcatag caggaatttt ggaagtattc tggtcaacga tgatgaaatg
    50821 gagtgatggt ttttctaaaa tcaattattc tttttacaca gtgattggca tgattgctag
    50881 tttttacttt ttgtcaaagg caatcaaaag tttgccgatg agtctctctt atcctatctg
    50941 gacagggatt ggcgcagttg gttcggtcat aattggtgtg gtcttgtttc atgataagct
    51001 gaatctttcc acttggttct ttgtggggat gctactcatc agtatcattg gcatcaagat
    51061 tactagcggc cactagacac ttggaataag tactgatcag aaaaaataag cctttttatt
    51121 taatattcaa tttttttatg aaaaaataag aaataagtcc aatgacctag cgacttctcc
    51181 actcatcagg tgtatgcttg tactatctat agaaaaggag tgaatatttt tgaaaagtct
    51241 ttcggtccaa gaattatcca agaactttgg tcacaaacaa gccctcagcg atgtcagttt
    51301 tagcttatcc cctggcaaaa tcgttggatt agtaggtcct aatggcgctg gaaaaacaac
    51361 gatcatgaaa gctattttag gactgatcca ttactcagat ggaacaatct gtattggtga
    51421 aaatgagatt tctccctcta gtcataaagg gttggaacaa gtaggagcat tgatcgaata
    51481 cccgggtatc tatccattct taacaggcta tgatcatctg aagttattct ctgaaaccaa
    51541 cgatgtatct gctatcgaca ctatcgtgaa tcagctcaag atggaaaagt acattcacaa
    51601 aaaagctaaa tcctactcgt tgggaatgaa acaaaaattg ggaattgctc ttgccttact
    51661 gaaccatccg tctatcgtta ttttagatga gccgatgaac ggtttggatc cacaagcaac
    51721 aagagatgtg cgaaaaatca ttaccgactt ggctactcag ggcacctctt tcttgatctc
    51781 cagtcactta ctcagcgagc ttgaaaaaat ggtcgatgag ctgatcctga tcaatcaagg
    51841 aaagatcatc aaacaatgta caatggctga attgaaccaa acagcgcaag atttcatcgt
    51901 tatctctaca acaaatgatc tagctgctcg aacgatcttg acagaagctg gatatacttt
    51961 ggaagatcct gataaaatca agcttttaaa agaaaacgaa gaattattag gaaccgtgat
    52021 ccagctattg tctgcacaaa atatccatgt gacagacgtc cagcatctga cgaatgattt
    52081 ggaatcttct ctattggaaa ttctggattc agtaaagggg gaagaagaaa aatgacattg
    52141 cttgtaaaac aagaattatt taaattgatc aagaaaaagt caactgctgt tttatctgtt
    52201 ctattagttg ttttgctcat aggaacagca cttctagcca aaaaatacac gacgatcatt
    52261 gatccagttg aaatgactgc tcagcttttt agtgccacat cttggattgt ctttatcatg
    52321 attgcagctg caagcacgat catttcgatg gaagcacaat atggtacatt gaaaaatctc
    52381 ctttatcgaa agtattctcg aggagaaata ttagtaagca aatggatcac attagttatt
    52441 tattctgttt atttatacct tttagctatt attgtcactg tgttgatgaa actgattctt
    52501 ttcccttcga tttccttcac ggagaaggtt tctactggtc aaacactgat ccaaagcttg
    52561 ttcacttata ctttgggtag ttatatcggt ttatggctga ttttaagttt agtgttgatg
    52621 attgcttgct ttatcaatag ttccggcgca tccatctcag caggaatcgt cttttatttt
    52681 gcttcgtcaa tcatatctgg tatccttatt gcactcatcc aaaaatggga gtggatcaaa
    52741 tggaatccga tcagtatgtt gaatctgcaa aaccaaattg gaaacgaaga gatcatgaag
    52801 caattgactc atctttctac taatcaaatg ctattcggta atttagctta catcgttttg
    52861 ttcttagcat taggatatct cgtatttaag cgaaaaaatg tatgatgact catcaaaaaa
    52921 gaggctgtga aagagacgtt cagccttatt gccgattggc tgtctcttaa acaccgttta
    52981 ttctgaaaaa ggagctgtga caacatttgt gtcacagctc ctttcctagt atgtttttga
    53041 ataaacgaca ggctcacaac ctctctttat acttctttta tacttctata cgtgaagcat
    53101 cccagtggca aataaaacca ttgcaatcac tccgaccatc gtcacaccta taagtaaaat
    53161 cttatctaag tggatatgtt gtacaggctc gttttgctcc ttacgtgctt tgaggtaaaa
    53221 ataaatgcct ggcaagaaaa gaacaagaac aagcattact tcattaaagg ctacgactag
    53281 catagcccat acttgaaagg cacttgctaa aagccctact aaaaattgga cccattcttt
    53341 ccgctgataa gaaagtttca tttggtacaa tcctaagaaa agccacgtga agaaaatagc
    53401 tgctgtacca agtgtgtaag caaagttata agcactgtca gtgaataata atgaaagtaa
    53461 aaagacattc gtacataacg tcgtcaatac gatagcataa gttggtgccc catttttgtt
    53521 gagttttccc catgctttag gcaaaagtcc gtcttcagcc atgtttccca ttgtttcaat
    53581 cggtaagatc gtccatgaga gccaaacacc aactaaagaa atgatcaaac cgccgttgat
    53641 cacgactgct ccccatttac caaccatcat ttcaaacaca tagcccatag caggctgcgc
    53701 cttgatcgtt tgcagctgat tcatcgtcat tgtcccatat ggaagcatgg aaaccaagac
    53761 gtaaataata atcaagccga atatccctag aatcgttgct ttcccaacat ctgattgttt
    53821 ttttgctcgt gaacctacga cagaggctcc ttcaatacca acaaataccc aaagcatcac
    53881 catgatgcaa ctcaatactt gactggaaaa cgggatcggc tgtccattcg cattcaatat
    53941 aatgtcgcta gaaaagttat caatgaattg ttggatcgaa aacgtgctga tagctactac
    54001 aataaataaa aataatggca ctaatttaca gaatgtgacg atagcattga cgaaactagc
    54061 attttcgact ccccgattca ctagccatgc atatccccat aaaaagactg tactcatcac
    54121 gatcgatgcc agattttgcc caccttcaaa tactgggaag aaatatccta atgcgctcat
    54181 caacaatgtt gcaaaagcta cgttgcctaa ccagcatgtg agccagtaac cccaaccgct
    54241 gataaaacca gcgaaacggc caaaaccttc ttctgcgtaa ctaaagatcc cgccttttaa
    54301 atctggacgt tttttattga tattattgat cgacaaggag agcatcaaca ttgctgttcc
    54361 tacgagtacc caactgaaaa tagctgggcc gccagccgat ccggagatgt ccgtcataat
    54421 accaaatacg ccacctccaa tcgctgaacc aattactaag gcagcaagtg gaattaaacc
    54481 aattcctttt ttctgttgct ctgtatccat gtaagcatcc tccaaaataa aaccgctttt
    54541 atcaaaaagt ataacaaacc ttttttattt ttacttaatt aataaaaact ttaatagaaa
    54601 tataattcta ccggcttttt tctcattata caagcaaagc gcctagtccc tttccaaatt
    54661 acaccaccaa aaaacttaaa aaagatgcta tactaaaagg aaagaattgg aggatgatcc
    54721 atgaacattt tatatatatc gatttcagga aatacgcgtg cctttgccaa acatctagca
    54781 gaatatgctg aaaaaatgca tgcagaagat cctgtcaatc ctgaagttac tttaaaagaa
    54841 atccatgaaa atagtgattt tacgaaagaa acagaaccat tttttacttt cgttcctact
    54901 tatttagacg gcggaaatgg tttagataac ggtgatacag aaatcttgac cgaaacgatg
    54961 cgtgaatatc tggaacatga agacaatcat aaactttgtc ttggtgtagt cggtagcgga
    55021 aataaaaact tcaataatca gtattgtcta acagccaaac aatatgcaca aacatttggc
    55081 tttcctttct tggcagatta tgaattacgg ggaacaccat ctgatgtgac acgaatttat
    55141 cagattttag cagaaaacaa taaataataa aaaagaagaa gctgaaaaat agatttcagt
    55201 ttcttctttc gtttctattg tttctatcat attaagcttt gacatccatc acaggtgctt
    55261 ttgcttttgc tttacctgtt ttttccaaga caaagttttt tacacgatcc atattggtta
    55321 ccaagacgat catggatgtt tctttgcctg ctgctttgat cgcttctaag tcagcttctg
    55381 ctacaagcgt atcaggtgtc acttgctgcc cttctgttac tttcacatca aatggcgtac
    55441 cgcctaagtc aactgtgttg attcccatat gaagcaagat ttctaaacca tttggcgttg
    55501 tgatcccaat agcgtgtttc gttgggaaga cagagctgac taccccagta actggagaat
    55561 agatatgtcc gttttctggt tctacaaagt agccttcacc catcatcttt tgtgcaaaaa
    55621 ctggatcact tgctttatct aaagaaacaa ctgttccgtc agcaactgat gagaggatag
    55681 tcacactttc agctgaagtt tgaggtacta ctttttcagg cacttcattt actgtggctg
    55741 tttcagtcgc taattcttct ttttctaaac ggtctttagg aataccgaag aagaatgtag
    55801 caacgaagcc accagcataa gctgccaata atccaaggat gtagcctaac catttaccgt
    55861 cagagatcaa tgggatcaaa gcggctcctg aaggtccaat agcgatagcc ccgacatttc
    55921 cgatcattcc gatcactgcc ccgccgatac ctccaccgat acaagcagta ataaatgggc
    55981 gtcctagagg taatgttact ccgtaaatca atggttcgcc gattcctagg atcccgactg
    56041 gtaaagctcc tttgatcatt tctgttaatt ctttatcttt tttgcagcga atccataatg
    56101 ccaatgctgc acccacttgt cctgcaccag ccatcgcaag aattggaagc aatagcgtac
    56161 gaccagtttc atcaatcatt tgcacatgga ttggagtcaa aatttgatgc agtccgaaca
    56221 taaccatcgg caagaataat gtgcctagaa cgaagccggc aaatgctcca ccaacgccaa
    56281 gtacccagtt gatcccaccg accatgccat cagaaatgaa acctgctaaa ggcatgatga
    56341 agaaaatttc aatcagaccg atggcaatca atgaaagagt tggtgtaacg atgatatcta
    56401 ccgcatcagg tactacttta tgcagttttt tctcaacgat tgacaatagc caaacagcga
    56461 agatgacacc taggatccca ccttgtccag ctgcaagagc ttcaccagta aataagtttt
    56521 tcagtggtgc ttccggattc atccctgtca gcatcacaac ggccccgata actccaccaa
    56581 gagttggtgt tgcaccaaaa acttgtgcag cattgatacc tgtatagata actaggtagc
    56641 taaacatccc gtttttcaag atgttcatca catcgatata ttgttgccat gttgctgcat
    56701 caagtgttcc ggctgtgact aagtttgcta aaactgcggc aatccctgcc acgatcccag
    56761 taccgacaaa tgcaggaatc attggcacaa agatattaga aatgtctttt aataccgatt
    56821 tgattttaga tggtttttgt ttcgattttt gtgccgcttt catttcttgt gcccgttcgt
    56881 ttacacggtc ttttccagat gctgatgaat ttgctgtagc tgtacttaca gaagaaagtt
    56941 tttctcctaa tttcacgcct gccaaatcaa ccatttgctg tgctactttg ttcactttcc
    57001 caggtccgat gatgacttga agctgttcat cttctactac accaagcact cctggaatcg
    57061 cttttaattc agagacattt acaagatcat cattgatgat cttcatatgc acacgagtca
    57121 tgcagtggac aatgctttct acattgccca tgccgcctgc ccctttataa atttgttttg
    57181 ccagttcttc caaagtcagt tcgttttttg ccatggtctt ttccccctca taaggtccct
    57241 tttacaaatc cgtttgcttc agctaatttt gcttgagctt cctctttatc actatttgtc
    57301 aaaatcatga cgatagccag cttaacattt tgatctgctt cttcaaagta cttttcagct
    57361 gtttcgtaat cagcttctgt cgcttgcatg atgattcgtt ttgagcgttc gattagtttt
    57421 tcatttgttg gtttgacatc gaccatcaag ttattgaata ctttacctat accaatcata
    57481 ctgatagtag aaatcatatt caagataagt ttttgtgctg ttcctgactt caatcgagta
    57541 gagcctgtca aaaattctgg acctgcatcg acttcgattg ggaaatccgc gtgtttactg
    57601 atttcggctt gtttattgca agaaatcgtt cctgtgacag caccgatcga ttttgcgtaa
    57661 tctaatccac cgatcacata tggtgtacga ccgctagctg cgataccaat aactatatca
    57721 ttttttgtca aattcagctt gattagatct tcttgcccta gctcataaga atcttcggcc
    57781 ccttcgacag ctacagtcat tgcttcttct ccaccagcaa ttagacctat gaccatttcc
    57841 ggttctacac cgaatgtcgg tacgcattca gcagcatcta acacacctag tcttccactt
    57901 gttccggctc ccatataaat cagacgtcca ccttttttaa aggactcaat cgtgttagca
    57961 atcactggtt cgatacttgt cagttctttt tcaaccgcag cggccacttt ctgatcttct
    58021 ttgttcatta gttgaacggc ttgagaaata ctcatctcat ctaatccaaa agtttcttgg
    58081 tttctgcgtt ccgttgttag gttctctaaa ttgattttgc tcatttttat cttccttctt
    58141 ttcttataaa ttgatagttc ataccagctt tgatttggtt gatcaatggt agctcttctt
    58201 tgataacttt agctactaca ttcacttttt catccgctgg caaatcatat ttggttaatt
    58261 ggatctcacc catatagcgc aaatactttt cgttatctaa agtaatagac cctttcatac
    58321 gcgtagctgt atttcttgct gggataggcg gaatctctcg aaaacgtgca tctacgcttc
    58381 gtatgacatc tcttgcatcg tcttgccgat tcgtatgctt ccctaatata tattcgtaaa
    58441 attcttcatc tacaggttcc gtatggagca agactgtctg ttctttttgg aaagaagcaa
    58501 attgctcctg aacgttttct gacagacctg catctccgat gtaaacaata tccgtgttac
    58561 ttgctaatag atctagagcg cctgcaagag gatggatccc tcgatgttct tccaaagttg
    58621 gcaatccttg atatagtggg cctctcaact ctgtatctcc tggtacaaaa ccttggacaa
    58681 ggagaccttg aattttgagc cattgatttt ttttctgata ccattctttg tccagccctg
    58741 tttcgggacg tggataataa ttatgccaag cttcaatctg tgagaaatca gcttctgctt
    58801 ctttcaattc atcgatatct ttaggcgtga tcgtgctagc attcaaactg attttcaatt
    58861 gatgtgacca gtcggcaatc tgctgattgg aaatatgata atccattctt aaacctgtta
    58921 caccaattgc tttcaaaggc gttagatctt ctaatgaaaa acccgctcgt tccaatgcct
    58981 ctcctgaaat atcgaccatc aattctagtt tattcttttt cgcttcgctt cctagttcga
    59041 tcaatcgctt ttgatatgcc gaaacatcat cttctggtat atgcatggaa gtgaaaatac
    59101 cgacaaagcc attggatgcc atttggcgga tatactgttt cttctcttct gacaaagaat
    59161 cgttcataaa tattgaaaag ccaaacatat tatccctctt tttctgtatc cgtcttcatt
    59221 tctatgacta gagtatatat ctaaagaaac aaaatttcaa tacttttatt aaaataatta
    59281 aatttcattt ctaaaggttg agtttatatt atcaaaagaa ttgtcataac ctaaaaaagg
    59341 cactgctaag caaaagcagt gccttgaaat attttattta aataacacaa aaacataatt
    59401 actcataaga aaccaattct gtattatcta ccatgaatgt aaagaacccc tcattaggca
    59461 tcggatgaaa ataagcattg atcactctta tcaaggcatt atggcaaact aacagataga
    59521 cattttcttc gtcttcgatg cattctttca ataaaggaac gatccgtgca tacacatcta
    59581 agactgactc cccatttggg aatcgtacag cgaacgctaa acgtgctttt tgaaagttct
    59641 catctttgct tggcagtcca tcataatccc caaaatccat ttctaccaat cgttcatcaa
    59701 cggtcagcgg caagctgaga cgatcagcaa ctgcttgtgc tgtatctctt gctcgttgaa
    59761 gaggggaatg gatgattttc gtgattggaa caggcaaatc tactaccttt tctgctagtt
    59821 tctgtgcctg catctgtcct ttttcagtca gcggcacatc tgcccgtccg caaactaatc
    59881 cttgtgcgtt ccaagttgtt tctccgtgtc tcgttacata aagcatgtga ttctctcctt
    59941 cgttggcaaa gttcccctta accatacctt gttgttcttg agattacaag ggttagattc
    60001 tctcaagaga aataatctca gtagatactt tatccaggaa ggtttgatca tgttccacta
    60061 gtaacatggc aggtttcacg ttcaagatca gttgttctaa ttgttcttga ttgaagacat
    60121 ccaaataatt caatggttca tcccatgtat atagttcagc tggctgtgat aaagatttag
    60181 ccaattccac ttttttccgt tggcccatac tcatctgctc gatcttgtta tgaaaaacat
    60241 ctctttccat cccaagcttt cggaggttgt tcaaaaatgc ttggtagtct acttggtttt
    60301 tctctgcaaa ttccgccaac gttcctcgat tgtcttcata attttggctt gcataactaa
    60361 tgctcagatg ttttggctgg tatttttctc ctataacctt gccgttgaat gcccccagaa
    60421 gataatggat aatggatgac tttcctgcac cgttaggacc tgaaatcgcc acccgctgat
    60481 gaggctcgat tgtaaaatga attggctcga ataacagatt ttcataccct aattgaagat
    60541 cttctacgct taaaagtcgc ttatggtgag acgcttggct attcatcgtc aaagaatcga
    60601 tatattcgat atcttttaat agtttttctt tctcgctgat ctgggtctcc atccgattca
    60661 cgattgcttt ggatcgtttc atcgtccgtg cagcatcagc acccactgct cctttattca
    60721 ctcgtctaga ttcagtatcg atgaatccga cttgtttctt tgttttatct ccttctcggg
    60781 aacgagacca ttcggctttt tcagctgctg ttttctttag cctactgact tcttttttca
    60841 atttttcatt ttgagccatt tcaaattcat cacgaagttt tttctgttct tcatagatag
    60901 agaaattccc ttgataaagt tccagttgac ttttttcgat tgctaaaaca tggtccacta
    60961 cttcatcgat aaatccccgg tcatggctga ccacgatgaa gccttgtttt ttctttttca
    61021 aataagccgc tacttgtttt ctaccagaga tatccaaatg attcgttggt tcatcgatta
    61081 acgggaaatg agtgtcatcc acaaataaaa gtgccagtag gacttttgtc ttctctcccc
    61141 ccgatagtgt gctgaattct ctccataaga tttcaggatc tgtttgcatc aattggagct
    61201 ctctttcgat ttcccatatc tcaaaatccg taatatcatt taacacgtaa taggttaaac
    61261 gttctttatc ttttgtctgt tgcgggaaat aggcaaattc ttgctgatgg attacttgcc
    61321 cttgataagg tagtttgttt tgtagaatat tcagtaaagt tgtctttcct cgaccgtttc
    61381 gtccgataag tcctagtttc cattgtgtgt caaaatttag atttgcttgt tcaaataata
    61441 atgtgccttg gctgtcgtag ccgaatgtca gattttttat ttcgatttta gacattttcc
    61501 atcacctcgt aaaaaaagac cagtcctatt ttcagaactg gctaaagagg atgcaagggt
    61561 tggatacaca caaaaagacc catacatcga aaaaaccaag ccaatcccga aaatctgcac
    61621 actgcttcct tgtctccaca aggtacagtc tgaatgcagc tttcatcaat cgacttaatt
    61681 tttcaatgca cggatccctc actttgtcct atatttgaaa ttacgatagc ataaagaaaa
    61741 tgattttgtc aactacttcg ggaggatggt gaaaaatctg ctaagtgtct gtcctaagat
    61801 ttttgttttt tctaatgttt gcctgtgttc cattgcttct tctaaaccta ttggacccaa
    61861 atgaatactt aagacaattg ggagaaaatc agaaagtcct tctagctctt ggtctctact
    61921 tccgcaaata gcgattattg gttttcgata tttttttgca agcactgcta caccgtatgg
    61981 aacttttccg tggatcgttt gctgatcgat ccgcccttct cctgtaatga tgacatctgc
    62041 ttgttcgatc tttttttcca atccagtgat ttggctgact aaatcgaaac cagaaaccat
    62101 cttcgctccc aacaaaaaaa gggctccacc aataccgcct gctgctccac ttcctggaat
    62161 atcatctaaa tccacctccc agaaatcttt tatttgctga gcaatctttc ctgcttgttt
    62221 atctaagaaa gctagcgtcg tatctattcc tcctttttgt cttccaaatt gccaagcagc
    62281 tccttgttga cctgtatatg gattggtaac atctgcagcg ataatcaatt ttactttaga
    62341 aacaagaacg tttcttcgat caaaatgaag ttttttagta gataataaag gatttccttc
    62401 tgtgtaccct tctaaagaag cacccaagga ttggagtaat cctagaccac catcgctaca
    62461 cccgcttcct cctaaagtga caataatttg ttctacttct tgaagcagtg catctttaat
    62521 aagttctcct aaggcataac tggaagcaag tcggatagtt tgatccgttg gtttatcaag
    62581 tagatctaac cccaatgctt gtgcagattc gatgactgcg gtgttttttc cttgccaagt
    62641 tgtcaataaa tagctgattt ttcgctgacg gaataagaga tccatcccat caatggtacg
    62701 ccatgttccc ctgagcgcgt aatagattgc ttctgcagta ttttctccgc catctgcaat
    62761 cggcacattg atttttcttc ctttacgatc ttcccagcca tttagaactg cctgatttag
    62821 ttcaaatgaa gaagcacttc ctttaaatga atcaattgcc gccaaaatat ccatctgtat
    62881 ccctcacttt cttcttaagt aagacacttt ttttcatttt tttcaaacaa aacaatgcta
    62941 ttttcttcca tttttctata tactaaaagg gaactcattg aataaaggag agaaaaaaca
    63001 tgaaaatcgc aatagctggg gccggagcaa tgggcagccg aatcggattg atgctacatc
    63061 aaagcggaaa tgaggtcctc ttgatcgatc gttggcctgc tcacattgaa gccattcgta
    63121 caaatgggtt gattgctgac tttaacggta aagaagtggt cgcaaaactg ccaatctatt
    63181 caccagaaga aatcatcgaa agcaacgaac acgtggactt gatcgtagca ttaacaaaag
    63241 ccaatcaatt agatgatatg ttttgttcga tccaatccat tattactgac aatacttatg
    63301 ttttgtgttt actaaatgga ttaggtcatg aagatgtact ggaaaaatat gtgccaaaga
    63361 aaaatatctt atttgggatc acgatgtgga cagctggtct agctggtccc ggaaaagtca
    63421 cattgttagg tgatggagaa atcgaactag agaacttgga accagaaggc gaagcattta
    63481 caaaaaaagt tgtagaagtc tttcaagaag caaatttaaa tccgatctat agccataacg
    63541 ttcgttattc catttggcga aaagcttgtg taaatggaac attgaatggt ttatgcacga
    63601 ttttggattg taatattgct gaactaggcg cgcaaaaagc ggcagagagc atggttcgaa
    63661 caatcgtatc tgaatttgct tctatcgcag caaaagaagg aatcatacta gatcaagaag
    63721 aagtgtacca acatattgct tctacttatg atcctgacaa catcgggttg cattacccat
    63781 ctatgtacca agacctgatc aaaaaccatc gtttgactga aatcgactac atcaatggtg
    63841 ccatttggcg aaaaggacaa aaatatgata ttgctacacc atattgtgcc tttttgaccc
    63901 aattagtcca tgcaaaagaa ggaatccttg gcgcagaata aaaggctctc tgatgagaat
    63961 cagctgaatc agcagctggt tctctttttt taagcccaat aaaagatcaa aaagaaaaca
    64021 caactctcat gatgccataa gaattgtgct tgtttgtttc agtacataat ctcttcaaaa
    64081 tgtaggtttt ttatttgttt tcaacagagg agaggtcata ttcgtattgc tcataaatag
    64141 tggaatcgtt agtgataaat cgttttgccc aattttctgc atcataaaat tccaatagct
    64201 ctgataggat tggcttaaat ggtgtatgca gaaattccgg taattcatct aaatcacgtt
    64261 ctcgaagcaa aaaaatattt tcaggacgat aaaaatgata atgagcaatc gcttgattat
    64321 ccgtcactag tttcttttga aaatacatgg attcaaatgt ccgcaaagtc actccttgct
    64381 gaccctcccg caacagttcc agaatcccgc gcgattcccc tgtttttttc aggtactctt
    64441 cataagtaag atatccaggt tgttcattcc ctcgatgtgg aagaatgaaa tagttggtcg
    64501 taacatctct ttttataaat tcctgcttat agctttctgc tcgttctttt ctcccattat
    64561 tcgttgcacc aaaaaataga tccgtctttg gttcgctaga agaaaaattc atatgtttcg
    64621 aataaaatga actattatgt ttcagcccaa gttcttttgc ttccaaaaaa tcaaaatgat
    64681 aaatctcatc gattgccggt tcatcttgtg cctgcttcag catcgcctcg tgttctgctt
    64741 tgaagtgatt ccaaaaaaat aacacaattt ttgcattggt aaatgggcgc acgcgtcgag
    64801 ccatctccat atcaaatcca taatctaaaa aaacgatcag ctgataattt gccaactgtt
    64861 gtctagctga tttaatgaat tccgactgta gtaaatcttt tccggaccaa acatctaaag
    64921 agcggatgga aggcaaaaaa taaagtgatt tattttttgc aactagcagt acgtcatttt
    64981 tgttcatctt ttccgcctca ctttctctgt cactttttcc tatgatagcc tgtttaaata
    65041 gtaaaaagcc agtaaaacgt ttcctatatt tgtatgaaaa tttaacattt gtatgaaaat
    65101 atgatgaaat aaatcattct tctattaaaa ttcgcctaaa agttttctga atagttgtaa
    65161 ttgtctgaaa atttgttatc attagtcatt gttaaatatt gctatttatt cttaatataa
    65221 attttgattg tgaatttaaa agaaagaggt catttatgga agataaaaaa ttgaaaaaac
    65281 aacttagctc cagacatatc accatgttag ctttaggtgg agcaatcggt gcaggtctat
    65341 ttaaaggaag tggcgaagcg attgggatcg ccggcccttc tgtattgatt gcttttttga
    65401 ttggtgggct gattttatat atcgtgatga aaggtctggg aaaaatcgtt ttaagcggtg
    65461 gcgacacgca tcacggatta tctggtttga tacgccctta tctaggtgct cattctgctg
    65521 attttactga ttgggtctac tggtctatgt ggattatcaa tatcatcgct gaagctgttg
    65581 cagctgcttc ctttttgcag ttgtggttcc cgcacattcc agcctgggta tttgttttta
    65641 tgttggctgt tttaactacg atcatcaatc tttattcggt acggttattc gcagaaacag
    65701 aatattggct ggcttttgct aaaatcagtg tcattatctt actgatcatt tttgctactt
    65761 atcttgtcgg tcagcaaatg ttgggcacag gcgttttccc tacccttcag caattgactg
    65821 accatggtgg gtttactcct catggtatga agggaatcat cagttctttg cttgtagtta
    65881 tctattctta cggcggttct gaactgattg ctatcacggt aagcgaagca gatgatccta
    65941 aacgtgcgat tcctaaagca atcaaaggtg tcatgggaag aatcatttcc ttttacatca
    66001 ttcctttgtt tttgcttttg attctttttc cttggaatac tttagcaggc acgaatgtca
    66061 gtccttttgt gatggtattt gaaaaaatga atatcccatt tgcagcggat atcgtcaatt
    66121 ttgtgattgt ccttgctttg ttctcatcta tcaattcggg tgtgtatgca tcttcaagaa
    66181 ttttgttctt ccgtttgaag gatcgaaaag gttcctctag aaaactagct gttttaaaca
    66241 agcatcaagt accgcaacgt gctgttttat tttgtaccag tgttctttat cttggtgtag
    66301 ctctttctta ttttgtcggt gacaaattat ttggctatct ggcaggttcc ctttcgtata
    66361 cagtattatt gatctggatc attatcagtg cggcatcctt tgtactggca ctaagaaaag
    66421 gaacattatg ggataaagga atcagctttt ttgcattagc tgtcttagga ttgattttcc
    66481 ttggtatcct gttcacgaac tccattgggg taactgtatt gactggcctg ctttacctgt
    66541 tcatttattt cagttatcaa aaaaagaatg atgcgttcgt attgacgaat gaatgaaatc
    66601 gatagaaaat tttattttat ttatgtggaa tagatggagc tattgaagaa aggagttgtg
    66661 acaaaagtct tgttgcaact cctttttccg aataaacagt ctcatgacct cttggtaaac
    66721 ggtgttcaaa aaccctctgt gcaaaataat tgattgttct ccatgctcat gacatgatag
    66781 aagaaaggaa tgaaaaaaag gagtttgttt taaatgaaaa agtattggaa gtttttgttg
    66841 atgatcggtg tttcaacggt agttatgttt ggtatgatgt acttgaatgt ctatgcgctc
    66901 gatcatatct tcttcagtcg tacacgagta ttcatggcgt tgatgatggg tgcagtcatg
    66961 gcagtcatca tgctgttgtt catgtggaaa atgtatgaaa acaaaaagat aaatgttatg
    67021 atcttagccg ctagtcttct tgtttttgcc ggttccttgt ttatggtacg aagccaaact
    67081 actgtcaacg acacagcttg gatgaaggcc atgattcctc atcattctat cgctatcctg
    67141 gcaagtaaac gagctgattt aaaagatcct gaagtaaaaa aattagcgga agaaatcatt
    67201 caggcacaag aagaagagat cgacaaaatg aaaaaaatga tcaaagaaat ggaatgacca
    67261 ttatccgtcc aaataaaaaa agaggatgtt ccagaagtta tcagcttcaa gaaataagaa
    67321 gaagctactt ctggaacgcc gtgaataagg ggttgtgaaa aagctgccct gcatcaagta
    67381 ataagaacag ccaaacaaaa atagcttctc ctatttttcg tttggttagg cttattaccg
    67441 cagatgcaag cttttgaaca ccgtttatta agaggttgta aaatcagcgt tctgacctga
    67501 gtattagaga gacaaatgga aaaatagttc ctcatatttt gccatttttt gagctaatac
    67561 cgagggtcag ctgattgaac accgtttatc gagaggttgt gaaaaagtcg cttagtttcg
    67621 cgtattaaga aaaattttgt gaaatggctt tccacatttt tgtataaatt tggcttaata
    67681 ccgagaaact ggcttttgaa taccgtttat tcgtaaaagg gattgtgaca aaagtcttgt
    67741 cacaatccct ttttatgttt ttattgttct aattgcgctg tcttgcttac tgcttcttgc
    67801 ggtttcacaa atttttttga gattccccaa cctgtgaagg cactgaccat cgaaaacaca
    67861 ggagaaagca aactgaaaaa tacgaatggc aagtaagtga gtgtaggaat accaaatgta
    67921 cttgctacga aacttccggc aattccccaa ggcactaagt agttgattac tgttccacca
    67981 tcttctagcg ttctacctaa tacagttgga tcaaatcctg ctttttcata agtttcttta
    68041 aatgcattac caggcagaat aacagatagg aattgttcac caataaaaat atttactccg
    68101 atacttgtca tcaatgttgt aaaaatcaaa tttggtgtgt tcgtcatctt tcttgatact
    68161 cgttccatca cggttgagat caagccaaat tcgatcaaca atccacctaa tgacaaagtt
    68221 agaataatca atgacacagt aggcatcata ctttcgattc ctccgcggct aagcagtgaa
    68281 tcgatttgtt ggtttccagt atttgaaaca aaccctgatt cgatgacccc agccaacttc
    68341 gttaaggaag tttgtgggtt ttgaataaaa atcattccta ctgctacagc gatattcaac
    68401 aaaatcgtta aaattgccgg cacctttttc catgcacaca gtaacattaa aaataaagga
    68461 atcagtgacc agattgaaat agtaaagttt gcttctagaa catcagtcac ttcacgaata
    68521 gatgaaagac ttgcggcttt acttgtgtgt cctaaaatca tgaataaaaa gaaagaaaca
    68581 acaaatgccg ggacagttga ccacatcata tgcttgatgt gtttgaacaa atcggcatca
    68641 acaatagctg ctgctagatt tgttgattcg gataatggag acatcttatc tccaaaaacg
    68701 gcacctgaaa caatagctcc aacaaccagc gctggattta agcctagtgt tgtcccaata
    68761 ccgaaaaatg caatcccaat cgttgacata acagtaaagg cactccctac agcgctacct
    68821 acgattgcac acacaacaaa tacagaaggg acaaaccact ggacactgat caatttgaac
    68881 ccaatgacca ttagagttgg aatgatccct gcttgtatcc atacagcaat caatgaaccg
    68941 actaaaataa aaataaagat tgggatgatt cctggtttga tgccattgat gattccttcg
    69001 tgcagccaat ctgtcgggta tctttttatc actgcataca acatgaccat tccgatcgct
    69061 gctaagatcg tgatattagg tgagaccttt aatccgacaa cgccaatcgc aatgcctaaa
    69121 acaataacca ttaatacaag tgttgcttct aaaaaacttg gtgttccttt ttttcccatg
    69181 ataatctctc cttttttagt tgttcttatg ttctaaaaaa gttaagatat cggattactc
    69241 cgccgcaatt catccgcgat tcctccttta taaaaataaa aagacctgtt ttaaactaag
    69301 gacgaatgac tccgcggtac caccttaatt aaaaacagat ctgtttttca ctttcaaact
    69361 tttattcaaa tgtatggact ttccatgtaa ttcgtcaatt aggcttgatc ggttcacagc
    69421 gaccaccgac tttctgaaca aaacacctaa ccgctactgc gtgaaaagtt gacttgtacg
    69481 aagtttacct tccataagat catttgtcaa tgaaaaagaa aatatttttt catttttctg
    69541 aaaattattt ttataacttt cacacacaag tttatttttt actagaaagt agcgccctct
    69601 tgtttttttc ttgctactat ttcttgatgt tcttgcttga ttctttctaa tagctttggc
    69661 tctttcaaca gatcaagagc tgtattggcg agtagttctg ctgcaatcgc aatagaagca
    69721 aggcctttgt cacttttagc agcagctttg aattcttctg tgtgtccggc aatatatgtc
    69781 tcagagattg ctaccgtagg ctggattgtt ggtatgactt ggctgacatt tcctacatca
    69841 gaagaaccga gacttgttct ttgttccgtt tctatttctt catctggaac acctgcttct
    69901 tttgcatgct ggaagaataa gtcatcaaaa gaaggagtaa cgatgacatc atcaactgca
    69961 ttttggaaca atccaaactc aaaagtcgtg cccgtactta tcgcagcacc tcgtacgata
    70021 ttttccactt tttcatatac tttatctaat gtttgccgat ttcctgcacg taaatagaaa
    70081 cgtccagcag cgtaatctgg aatgacgttg gcagctactc ctccgtctgt aatgatccca
    70141 tggatattga catcttttgg caattgcaag cgtagagcgt tgattccatt aaacacttgg
    70201 atcaatgctt ccaaagcatt tactcctttt tcaggtgctg ctgctgcatg ggaagcgaca
    70261 ccgtaaaatt tgatgtcgac tggatcattc gctaaagatt ctgtcgtttt cccataacga
    70321 aaagctggat ggacgcataa cgctacatcg acatcctcaa aaaaaccttc tcgaacaaag
    70381 ctgcctttag ctgatccgtt ctcgccccct tcttcccctg gggtgccata tacacggatt
    70441 tctccaccag tttcatcaat gaattgcttc actatgctgg cggctaatac ggagtaagta
    70501 ccaaacaaat tatgcccgca tgcatgacca atacctggta aagcatcgaa ttctgccaaa
    70561 aaggcaattg tgggaccggg tttattggaa atataacgtg catcaaaggc tgttcggtgt
    70621 ccagctactt ctttttctac ccaaaacctt tctttttcta attgtttaat caacgctgct
    70681 gaggaataaa actcatagtt acttacttca ggatgttcgt ggatatctag agcaagtgct
    70741 tgatattctg gtaaacgata ttggattaga tccttcaatt ggtttgttga gattgttgtt
    70801 gtcataaaaa attcctccta tgctagtcat ttttcttatt ttctcccgaa tgtttcccat
    70861 gcaggcacgc ttgatccttt tgatgttttc tcgattactt tgactgtgtc ttctgtttga
    70921 taagcgtcta ctattttttg atacgtttta ttgttttcat cttcttttct tgcaacgatg
    70981 atattcacat aaggacgtgc atggtcatcc actggttcta agaagatggc atcagaagca
    71041 ggattaaatc cagcatctac agctacaccg ctattgatca ctgaaatgtc tacatctgac
    71101 aaagcacgtg ctgtttggga agcatctaat tcagaaatgt ctagattttt tctattctcg
    71161 gtaatatcag aaacagtggg cgcttgtcct tttgccttat ccactttgat caatccagca
    71221 gtttgcaata acagaagagc tctgccgcca tttgtaacat cattagggat tgctactttt
    71281 gctccgtctt tgatatcagc tacatccttc aaagtgttag aataaattcc cagcggtgca
    71341 ttgacagtat ttccgatcga tactaaatca gttccgtgtt ctttattgta attgtctaaa
    71401 aagaattgat gttggaaaga attcaaatca atcgatccat ctgctaaagc cacatttggt
    71461 tgattgtaat ctgtaaattt cacgtattcc aaattaatgt tctccttttt caaacggtct
    71521 ttcacgttgt cccatacatc tgtatcttct ccaataatcc ctagttttac gatagtttct
    71581 tttttgtcag ttgtatctgc ttttccttgg ctacaccctg ccaaccaaat aattgctaca
    71641 aatgtaatga ctacaaaacg aataattttt ttcatttttt ctcctccact ttcaatgtgt
    71701 aattttttta atcagttgat tactgataaa ttgacttaaa aaaactaaga ttagaatcaa
    71761 taatgtagcc acaatcgtta catctgtttg gaatcgatta taccctctcg atatagcaag
    71821 attccctaat ccgcctgcac ctactgctcc agccatggta gtcagtccga tcacgttgat
    71881 gatagtcaac gccgagaccc gaatgatacc aggcaaacct tctaacaaat acacacgtaa
    71941 aatgataccg attggactgg ttcccatcgc ttctgccgct tcgatcaccc caggatcaac
    72001 ttctagcagt gcgttctcga tttgacgagc aaaaaacgga acaactccaa aaatcaatgg
    72061 cactaaagct gctttcgcac caatcgtcgt tccaactaag aaacgagtag tcaatgctaa
    72121 aagagaaagc aagataatga aagggatgga acgaatgata ttgatcagct tatcaagtat
    72181 ttcaaatagc agacggttag ctagtaatcc attagggcgt gtcactacta acgtcacacc
    72241 taagatgatt ccaatcatcc cgccaatgaa tgctgtccaa aaagacatat atagtgtttg
    72301 cttcgtcgct tcgacaaatt catccggaat caaataaaca ttgggcaaat atgttttaaa
    72361 gaaatcagtc attttatctt cctccttcga tcactttgat acgactatct aaatcgtttt
    72421 tttgtaaaat atttattttt acaccagatt tgatcaaata atccaatgct tttttccgct
    72481 gtttggtttc tccagctaaa gtaacgatca aactccctaa cggcgtttct tgtaataact
    72541 ctacattgcc atataaaata ttcgctgtta cttgatattt gctgtacaga tgagcgatta
    72601 gaggttcgtt cgtctgattt ccaatataac ttaattccac cagccattta ttggcgatct
    72661 gatcggcaaa agcagaatgg gcaatgatcg tttctaatgc ttggtcaaga tgagtagctg
    72721 ttcgaataaa atctttggtc aattcttctt caggattgct gaagatctgg atgctgctac
    72781 ctttttcaac gattcttcca tcttccataa ccgctacctt gttgcagatt tctttgacaa
    72841 cttgcatctc atgagtgatc aggacgattg ttaaacctaa ctggcgattc aattttttta
    72901 acaatgcaag gatctgaagg gtcgttttcg gatcaagtgc actggttgct tcatcacata
    72961 ataatacctt aggttcattc gccaaagctc gtgcgattgc tactcgttgt ttttgtcccc
    73021 ccgacagttg tttaggataa gcagatgctt tttcttccaa accgacaagt tccagtagtt
    73081 cattcacttt ttgacgacgt tcctgtttcg attttccaga atactttaaa gaaaaatcaa
    73141 cgttgtcaaa aatagttcgg ctttccatta gattgaaatg ctgaaagatc ataccgatgg
    73201 cctttctttc ttttcgcaat tctttgggag agagctgact cagattcgtc tgattgacaa
    73261 tgacttctcc tgctgttggt ttctgcagca aattcatcac acgaactaac gtacttttcc
    73321 ctgcacctga gtaaccgacg attccataaa catcgccttt ttcaatcgtt aaatctacag
    73381 aatctactgc ctgtatctct ttttcttttt gtttgaaaca tacagaaaca tctcgcaatt
    73441 caatcattaa aattcctcct tatctaaaaa aagcgtcctc aagaaaatga aaatgtcatt
    73501 ttcttgagga cgcttttttg cgtgttacca cctcatgttc aagctgtgtt cacacacaac
    73561 tcctcttcaa gtacgatcat actctagcaa gatatcggtc gcagccgtca tcgccttaca
    73621 tctatgctcg ggatgaattg ctcgatggcc attttccaat agtcgttcct tgcttcttct
    73681 cagctaccga agctctctgt caaaggttct tctatcgtac ttaccatttc aatgcaaata
    73741 atattcaaaa aaaaagtcct tttactaaca taaactatgt cagtaaaagg acgacgtatc
    73801 gcggtaccac cttttttcgg aagtttcctt ccctcaagcc caacatctca aaaagagaga
    73861 ttggcgttcg ttttaacggt cgaacagttc cgaatttgcc tacttatcga caaattattc
    73921 tccaaggcca ttttcagctt ttcttacttg actcttctca ccagccagag cctctctgca
    73981 aagtttccaa acttactttc cttttcaacg aaatcgatat tttgttgttg ggattaatct
    74041 acatgaggaa aactgaaaag tcaagtacga aattcaaatt attttttcta tatttatttt
    74101 tctgtttttt tatttaacat ttcaataaca gttcgaagat cttttccttc cgcaagaagt
    74161 ttcaattttt ccttttcttc gacggtataa tttcggacaa aactggaatc aggtatcaaa
    74221 acaacgccta atcctgctcg tgaagcagct gttgctccta ctaaagaatc ttccactgca
    74281 aaggctgaac tagcttctaa tcctgttcgt tccaaagctg tcagataagg aatcggtgaa
    74341 ggcttgttct ccgacacttc gtctccgaat gtaaacgtgt ccaagtaatc agctaattta
    74401 aagtgatcca agatatctgt tgctcttttc gtaacagtgg tcgtagcaat gcctagtttc
    74461 atatgacgtt cttttaagtc tgccaatatt tcttttgcat atggttttaa gtggatggct
    74521 ccgcttgtca gctgttgata aaaatattct tcacgcttcg ctcggacttc ctgtactttt
    74581 tcagggctac ctgctgcttt cactaaaata tcaaaacttt gtttccagtt ttttccgccc
    74641 caagcgtcaa cgatttcttt tgggatatgg atatcaaatt gctgaaatcc ccaaagccag
    74701 ccatcacgat acgttttttc tgtgtcaact aacaaaccat ctaaatcaaa tattgcacct
    74761 ttcatctata cattaatcct ttccaaaaca atacacatag tttagcacga ctggtccaaa
    74821 aagaacagaa gcaaagaacc agccttctcg tttataagag ttcttggaat cgacggatat
    74881 agattttctt cacagctgtc acaagcgcca gataagcgat gactgtagca aataaccata
    74941 accagtaatt gccaggaagt ggcatcaagc ctaattcagc accaaaactt gtaaaaggaa
    75001 ggacagaacc gacaataatt cctaatgtag tgataacaaa catggcaaat gttgcgttgc
    75061 tttggataaa tggtactttc ggtgtacgca gtgcatggag cactaaggtt tgtgtccata
    75121 gtgattcgac aaaccatcct gcatggaata atgcgatgaa aatcactcgc tgtgaactat
    75181 ccaatgtatg gaaacttccg cccactacag caggacaaat aacaaaatac atcaacaagt
    75241 aagtagtaat atcaaatatc gaacttgttg gaccaaagta aaccatgaat tccccaatac
    75301 tagatgcatt ccattttttt ggctcgtcca aatattcttt atccatccga tcccatggca
    75361 aggaaatgca ggaaacatca tagatcagat tcaaaaacaa aagttgtaaa ggcagcattg
    75421 gtaaaaatgg caggaacgta cttgcaatca gcacggaaaa catattgcca aaattagaac
    75481 ttgctgtagc cttgatatat ttcatgatat tcccaaaagt ttctcgtcca gaaagaaggc
    75541 ctctttccaa aatcgtcaaa tctttttcta aaaggatcac gtctgcagat tctttcgcaa
    75601 tatccacagc tgtatctaca gaaataccga tatcagccac tttcattgca ggagcgtcat
    75661 tgataccatc tcctaaaaat ccgacagtat gaccattttt acgtaaagct gtcgtcaaac
    75721 gtgctttttg ctgaggattc aattttacga atacttcatg gtcttcagct acttgtgcta
    75781 attcatgatc actcatttcc gagattttct caccggtaac caattcattg atctctagac
    75841 ctacttgacg gcacactgaa cgtgtaacta attcgttgtc cccagtcaga acttttacag
    75901 ctacaccatg ttctttcaga gctttcaacg cttgtttcgt tgtttctttt ggtggatcaa
    75961 ggaaagcaag ataaccaatc aaaaccatgt ctgactcatc tttgactgaa aattctccaa
    76021 cgacgcttgg attggtcttt tgtgcgacac caatcactcg taagccatct tcattaagtg
    76081 actgtacttt tgcaagtacg gcttcttttc gttcttttgt taatggtgta acagtaccgc
    76141 caagatcaat aaatttagaa atgttcagca tttcttcaat cgcgcctttt gtgatcattt
    76201 gtgttttacc agctggatca gcaaccacaa cactcatacg acgacgttca aaatcaaaag
    76261 gaatttcatc cactttttga taattgatct tatctgtatc taaagtttct gttgcttcat
    76321 caatgatagc cacatctaac aaatttttca gccctgtttg atagtagcta tttagatacg
    76381 catggcgcaa aacacgatca tcttcatttc cttcacaatc catatgatat tcaagaatga
    76441 ttttatcttg tgtcaatgtc cccgttttat ccgtacataa cacatcgatt gcaccaaagt
    76501 tctggatggc attcaaattt ttgatcactg ttcctttttt ggccatcaca cttgctcctt
    76561 tgaccaaatt cgtcgtaacg atcattggaa gcatttcagg tgttagacca actgctacag
    76621 atagtccaaa aagaaaagct tctagccaat ccccttttgt aagcccattg atgacgataa
    76681 ctgctggagc catcaatgac ataaatttga tcagtagcat ggatgtttta tggatgccta
    76741 attcaaagct tgattgaatt ggtttttcag atagcgtttc tgctacatga ccaaatagtg
    76801 tttcatttcc aacagaaaca atgattcctt ccgcacttcc actgatgaca ttacttccca
    76861 taaagacaag attttcgtaa cttgtttcgc tttgctgatc gtcttcacat actttcgcat
    76921 gcttttctac tggatagctt tcccctgtca atgctgcttg ggaaatgaat aaatcctttg
    76981 cggacaataa acgcatatcc gctggtatca tatcccctgc tgaaagccga acaagatctc
    77041 cacagacgat ttcttccata ggaatctctg tgtactttcc attacgtttt acagctgccg
    77101 ttactttcac aagtgatttc agtttttcag ccgcttgatt ggaacgtacg gactgaatca
    77161 acgtcattgt cccgctgacg ataaccatag tgaagataat ggctacaccg aaaagatctt
    77221 tatctccagg agctgctaat acatattccg tgatgaatga aataattcct aatgcgatca
    77281 acactaatgt aaatggcgtg atgtatgctt tcaatatttc tacaatgaat ggtgtttttt
    77341 tgccatatga aatcgcattt tcaccgtaat tttctcttga acgttcgatt tgttcttctg
    77401 tcaatccatt tgctgatgca tggaatagtt caaataattc ttgtttcgtt tttccagcaa
    77461 aagctgcata gattttttgt gtatctttct ttttttccat ctcaatctct cctttgtgtc
    77521 caaaagacag ctgttctcgc tgcttttggt ctttagctat tcatcggatc gatagagaaa
    77581 aaactgaaag gggctgagaa cagatagata atagccctgg cctttcctct agatccttgt
    77641 ttttcgaatg actgtcatcc atttgttctc atctccttta ctaagtaatt ttaattcatg
    77701 acttccaatc atttttcgaa tagttatttt tccaattaga ccacctcctt tttatttttc
    77761 accgatgggg atttgcggca acaaaaaaac ctctcgccaa atactcagcg aaaggtttga
    77821 aaaagcatat taaaaaaagc ttctcagatc tcatcgttga gttttgacac tgtacaacgt
    77881 aaaaagcaga tacctgcttt tagctacctt atgaaaagcc ttatctcgac aattcctgtt
    77941 ctacccattg gcgtctctcg acgtttttgg gcagtagcct atgtttgtat aggagcctca
    78001 cctaacaaat cttattcggt tttccttcgt taatataaca actaaaaaag aggatgtcaa
    78061 atcaattttc catgtttttc atactttttt taaaatacac acgttatatt cctgtctcac
    78121 gcggttttat ttgtctcatt ttccacctcc cgctataata gaaatatagt aggaaacgag
    78181 gtgctgttat ggaaagaaca cttgttatta tcaagccaga cggcgtgaga cgccatttag
    78241 tcggaagcat catccaacgt tttgaagcaa agggactggc cattgctgaa atgaagtttg
    78301 aaactatgac tcctgaatta gcaaaagaac attatcagca cttgactgag cgcagttttt
    78361 ttgatgaact gatcgattac atgacttccg gtcctgtcgt ttatcttgtg ctggtcggcg
    78421 aggaagtgat cgatatcgtc cgtaagatgg ttggagcaac aaaagctgcc gatgctgttc
    78481 caggtacgat ccgaggagac tacgcgctgc cggggactga aaacatcatt cacgcttctg
    78541 attcccgtga tgctgcggta aaagagatcg cccgcttttt cccgccattc gatataaaca
    78601 aaccgtctga aaaagcggcg aagtgataca aattctaaac tgctggtcta gttgctgggt
    78661 tcagcaatgg ccagcagttt tttctctaag gacctccgtt gattctttcc taacatatat
    78721 tcgagcactg tgaagaattc ttggtagtct ttcgtctttt cttcccctaa agcagcagaa
    78781 atcaatcttt gataataatc tgccatcaat gtttcataga tcactgtact tctttcttta
    78841 tgtgataagc tccgtttcat atcttcattc acactacgtg cctttttcaa ccgaccattt
    78901 tctatataaa acgaagtcag gttcattaaa aaagtaaaga gatactgctc atgattgttc
    78961 aactgtgcta atcgtcgcat tctttttttg attttcaaat aattgttctc aatgaaccga
    79021 tcactgaata tccaaggaaa atcagctaga atagatagtt caaattgacc atagtctggt
    79081 atctgcatca agtattcttc aatgattcgg cattcataac gtaaaaattc aaattctgtc
    79141 tcagatactt ctgttttttc gaccatgtga agattcaaaa ccaaataata cagatcttct
    79201 gttttcttaa aatgcctacg gttattgctg atctctttat aaggatcaaa gctgtcttct
    79261 tgtacccgat ctagcattcg tctttttttc tttaacttta ttggttcatc cagctggttt
    79321 cgcatccatt catattctgc aagtgtcatg ttcattcgct ctaaaaatga tctcaatgtt
    79381 acaaatgaca tttttttcac tgaatttgtc tcaatcccga ctagagaagt cttaaaacag
    79441 attccttccg ctaattggga ctgtgtcaac ttcttgttga ctcgaagttt cttgatcaat
    79501 tcaccatcat acataatagt tctccttttt aatttaaatt tttccacatt caataaatag
    79561 atacgttaaa aaggaaaaat acacgaaaaa aataaaaaaa tgtttttttc ataaaaaata
    79621 ccaaccttca agcattagaa tgttgtctaa ctactgaagg ttggtttgat tgtttattga
    79681 ttattttttt gctgttcaac gtctgttctt gttactggat ataagttggt tgttgtttta
    79741 ttaccatttt ttgaaaagac acttgtcgaa tgttcgcctt tttgcttttc gattgcttca
    79801 ttacgttccg cttcattttt atagtcatat tttttcggat caatcgtctc aaatccgttt
    79861 ggcacataaa accgcaagag attttcctga ttcagcttat ctgaaagact taacgcagtc
    79921 ttgacttttt cctgatcttt ggagatttcc tcatcgattc ctgctgcttt cgtatcgatg
    79981 atttctcctg tctgattatt gtaagctttt cctcctagga cggtgtattt gggtgtcaca
    80041 aagttcccat ttcgaaaagc aactacttga tcatgctgag aagataataa gtctgtacca
    80101 aaatgaagat aatctttatc atcgattccc aatagatgta gtaatgtcgg caaaacatcg
    80161 atttctccac cgtattcatg attgactgtc cctttagtat aaccaggcat atggatcatc
    80221 aatggcactc gttgcatctg tgcgttgtca aattcatccc atgtatctgg atctttacca
    80281 agagcgcttg ctaaatcttt attatctgta ttcgagatcc caaaatgatc cccgtaaatc
    80341 acaaagattg aattttggta aataccagat tttttcaaat acgtaaaaaa ttgttccaat
    80401 gattgatcca gataatgtgc cgttcgaaca taattatcta ctgtgctatt gccagtattc
    80461 aaagatggaa agtcgaaatt cttgtcatcc gtataataag gcgtgtggtt ggttacggaa
    80521 agaaatttcg tgtaaaacgg ctgttgtaga tgctcaagat attgggcaga ttctctgaat
    80581 aaatctttat ctaatatccc ataacctaac gtttcgtcgg attcatcaaa ataagatcga
    80641 tcaaagaaat tgtcataacc taagttttta tatacatgat ctctattcca aaaactagct
    80701 acattcccat ggaaaacagc gcttgtatag ccttgctttt gtccaaggat cgctggtgcg
    80761 gcttgaaaga cattgtctga cccaagttct gtgaataatg agccttgagg taaaccaaat
    80821 gtgccagttt ccaacatatt ttcagcatca cttgtctttc cctgtcctac ttcatgaaag
    80881 aaattgtcaa agctgatcgt tgcttgattc tggaaaatac tatttaaaaa cggtgtgact
    80941 tcttgtccgt ctaccttcat attaatcaaa aactgctgga aactttctaa atggagaacg
    81001 atcacatttt tccctttagc gatcccaaat gtttcgggat ttggctctgc ataatgtttc
    81061 tttgtataat ctaaaacttc atcaatccca ttactgcttg catgcgcgcg aacactgcta
    81121 gtcattcctg ttttgattcc gtcataaata gtatacgcat cgattcctag atatttgaca
    81181 atatatgaac ggtcaaatgt tcgctgcagc aattgtggac ggttggcttc gctcagcgct
    81241 agatttcctg aaaaaataag ccctgaaaga caggtaacag cgatagccat cggtttgccg
    81301 acagggttgc ttttgatagg tattttcttg accttcaacc aaaccagtag cccaatgaac
    81361 acagcgatat ccagccagta gatgacatca tggggcttca tcaaagaaaa ggagcttcct
    81421 gacaatcctt gcgacacttt cgaaaagcct aatacagatt tgactgtaat gaaatctgtg
    81481 aattcccgat aaaaaataat attcaagtac aacaaaagcg tatttaaaat atcaatgatc
    81541 aaaagaatag ctaacgctgg ctttggcttt ttaatataca aagaaaggcc aaaaaacaat
    81601 aaggtagtcg caattgggtt gatccacaag ataaagtact ggatcgtacc ttccacacct
    81661 aatgaaaaat ctgcatagta ggcaatgatc gtcttcagcc agaaaaagaa aacagctgtc
    81721 aaaacgattg ctaaacgatt ttggcacaat tttttaagtt gtgtcacgta tatcacttct
    81781 ctctattcac attttttctt attttgctcc tgaaaaatga aaatttccta aaaaagttgt
    81841 tatcttaaga tttttttatt ctttctaaag attattccgt ccacttttca cagcataaaa
    81901 ccgctgcgat gtaagcgatt aaactaatga agagataaaa gtcttgtggt gaccgcttca
    81961 ctccacggta ttcaaaagcc agtttctcgg tattcgtaca aaaaaagagg ctgtgacaaa
    82021 attcttgtcg cagctcctta tttcttgatg caggacagct ttttcacaac ttcttcctta
    82081 aacggtgttc tcctgccaac tcctcggcca caagtcacaa tatttataaa acatgagaag
    82141 ctgttttttg aaattgttcc ttgtggctca gagttaaacg gcaggctcaa gacctcttga
    82201 tacacggtgt tcaatcagct gaccctcggt attagattat gtcaggacgc taattttaca
    82261 acctcttggt aaacggtgtt caaaagcttg catctgcggt aataagccca accaaacgaa
    82321 aaatataagg agctattttt tgaaattgct ccttgtggct cagagttaaa cggcaggctc
    82381 aagacctctt gatacacggt gttcaatcag ctgaccttcg gtattagctc aaaaaacggc
    82441 aaaatatgag gaactatttt gccgtttgtt tctctaatac tcaggtcaaa acgctgattt
    82501 cacaacctct gtttttcatt gtccatagga ttgatattgt ccttgtgatg actcattcgt
    82561 aataattgag gcttgatttt cttcacttcc cgttatcgtt tgtccactgc cagaatctga
    82621 aggacttgtt cctgtcgact cgtttttttg agaagagaca gttgttttct tgacttgttc
    82681 atttgtcttt ttccattccg ctaaacgatc ggcgaccact tttttgtcta ctttttcaga
    82741 ataagcggtg atcacttttc catttttcaa acgggctact ttgtcgccat catgagtcaa
    82801 aagcaaaacg gtcaaatgct tgtctttaaa ttgatattgt ctgagagaaa tcgcactaag
    82861 tacgtcatcg atattaataa attgattttc ttcttttcct tttggcaaat aaatgtccaa
    82921 ttcgcctttt tcgtaattgg cagttatttt atactccgcc caccaataag ttgagaattc
    82981 ttttttgaaa ttatctactg attctttgct tgctacgatt ttttctgttt ctttctgagc
    83041 aagatctgct gtcatttttc ctgaaaatgc tgcggataaa ataagcagta agaaaaaacc
    83101 gaataaccaa aagagaagaa acggtctttt tttcctcatg ctttcctcca ctcctattta
    83161 attttgacta ttctattata tacaaaaaat gaaatagaaa gacaaaaaag ttgaaaaaga
    83221 tcgtaaataa ttgaacttct ttttcacaaa atggtaagaa tggagaattt cacgcatttg
    83281 ctctcaacta ttctttctta agcctcaaat ccgtttttat ctgatacgtc tttgaaccaa
    83341 tgacccgatt ttttgattgt tctttttcca tcttgtgcta agtctactga aataaagcca
    83401 tatcgattct tatatgcatt ggtccacgac cagttatcca tacatgtcca catatgatag
    83461 cctaaacaat tggcaccttc ttgaatggct tgatggacat atttcagatg agattggaca
    83521 aattcgatcc gataatcatc gtggatcatg ccatcttctt tgataaatcg tgcttcgttt
    83581 tctacaccca taccgttttc agaaataaag cagtcgatat ttccataatg atctcgtaca
    83641 ttgatcaaaa tatcatagat tccttgttca tagatctccc atccgcgata aggattcatt
    83701 ttacgaccag gcatttcata attgtcgaaa taatcctcag gcattggacc gtttttagta
    83761 tcgattggtg tttcttttgc ttttacccgg cgtggctggt aataattgat acctaaaaga
    83821 tctactgtat tttctttgat aaccgtcaaa tcctctgcat ggatcacagg catgagatca
    83881 agttctttta ctatctcaat caattcactt ggaaactcgc cttttacagc tggatcaagg
    83941 aatgaacgat tgaagaacgc atctgctatt tgcgctgctt taacatcttc agggtttgat
    84001 tcgtctcttg gatagcttgg tgtcagattc aagatgatac caataacacc accttgctcc
    84061 atttcatggt aagatttgat ggctaacgct gaagccaacg cttcatgata gccaacttgg
    84121 atcgcttttt tcatatctga ctcttctgga taatgccatc gatataaata acctgcttcg
    84181 actggaacga ttggttcatt atgagtaaac cattttttta ctttcgaacc aaacaattca
    84241 aaacaacttt tggcatattt ttcataggct tcaaccgttt ctcggttcaa ccatccgcct
    84301 ttttcttgca gatacatcgg catatcgaaa tgatacagat tcacaaaggg ttcgataccg
    84361 ttttcaatca actcatcaaa ataacgatga tagaaacgaa cggcttcttc gttgattgtt
    84421 ccagattcat caggtatcaa acggctccat tggatagatg ttcgaaatga attatgccca
    84481 gtctgtttca tcaactgtac atcctcttga tacttcgtat aaacttgcga ggttttttca
    84541 ggtcctactt gatcaaagaa cttttgcggt tcttttttgt accaataatc aaaaatgttc
    84601 tctccttttc catcgcctga aatccttcct tctgtttgtg ggccacttgc tgcagaaccc
    84661 caccaaaaat ttgctggaaa ttgatatttt ttcatcaaag cacctctttt tcttttttag
    84721 ttcgttttag ttgattccat gtatgatatt ttccatcaca atcacttttt cattttcttc
    84781 ctcttctttt ttgattcgtt ttaacagctg ttctgctgct cgttccccga ttttatctgt
    84841 tggtggcgtg atcgtgattt tcggaaggat actcagatcg tttttatcta aataatcata
    84901 gtgactgaac gcaatatcct tcccgattct gacaccttct tgattgaaac attcgatggc
    84961 accaatcgac atattgtaat tgctgacaaa aatagcagtt gccccttttt ctaataatgc
    85021 ttttgccccg taatagccgc tttttctaga atagtctcct gtaaagacct ctaattggat
    85081 cgatggatca ttttggaccg cttctttggc tcctgctaaa cgttctcttg ctacgtagtc
    85141 tgtttgagtg gcagcaataa atccgatttt tttatgtcct tgttcaccat gatgagcgat
    85201 cacttttgct acactttctc gatcattcac taatattgta tcaatacctg ctggtccttc
    85261 tggacaattc aatgcgataa ctggaatact catttttgtg agcatttcaa atccagacca
    85321 ctcttcttcg gataagaaga caatcagccc atcgatcaca tgcttcatca ggtattcaat
    85381 tttttgttca attttttctg gctgatcggc aaacccgctt aataataagc tatacccatt
    85441 ttcttcagct actctttcga tccctgagac aacttccgac ccaaaacggc tggaaatccc
    85501 gtttatcaaa agtccaatag agaagcttcg attattcttc aaccctttag caatgatgtt
    85561 ttctttatag tccaacgctg aaatcgcttc tgctattttt ttcatgttct tttccttcag
    85621 ttgctgacca ttcaagtaac gggaaactgt tcccactgaa acaccagcca tcttagccac
    85681 atcacggatc gatgccatac attctcactc ctgccagtta catttgattt ctctttcttg
    85741 ttgttcgatt atgatgaccg cattctttgc atagtgttgc ttgtcatcaa tatccatata
    85801 actaaagtct tcagtagagc aacttcctct cactattaat tatacttaaa caagtatttg
    85861 aaccggttca tttttaatat agcatttttt taaaagattg caacactttt ttaaaacgct
    85921 ttctgaaagt ggcggatttt ttgccttttt aaaattttat tctaaaattt actctatttg
    85981 tgggtgtttt gtgcgttttt ctcttccatc cgtttgaagt tttacattcc aatggtataa
    86041 tttctttatc ctatcaaatg ggggaagtat tttgaagaaa ttaatcgtac tatttatttt
    86101 gtctgcggga cttttgacat tgactggctg tgatttgttt ggcggctctg accaatcctc
    86161 ggacgaaaca accgattctt ctgtcttaaa agcggaaaaa gcagatacca ccaacagtgt
    86221 atatacgcta aaagtacgta aagatatgga tttatccgcg ggacagttga catttacaga
    86281 taaaaaaatg gaatggacac gcacgtatca gacacaagga actgattctt ctgaatcatc
    86341 tgaagaaaaa acagtgctga cagatatcaa gatcactacc aaagatgacg aatatattat
    86401 ttcaggaaaa gaaaataaaa aagaaacaac agtcatattt acaaaaatcg gtaattaccg
    86461 tttgaaggat gaggatggca acatctacag tctatagtgc cgtctgttgg atcttctttt
    86521 gtttctcccc ttcttttctg ctatagtaaa gaagcaagat gattgtaaag gagacgaaat
    86581 ggatgatcga tagtcctgat tattgtacat gtaataacaa caaaaatatc catacagaat
    86641 ttaatgacca aggaagcttg agcatatgcg acaactgtca caaactagtc aaagattcat
    86701 ttaaaacatt tgaatcttat cctgttcaaa attatgtaaa aagtagaaga agataaacaa
    86761 atccaagcaa aactcactat ggctgatttt tatgaacttc aaactcagct tcttcctttg
    86821 atcaagcttc atcagtaaaa caaacagtgg atcatttcag tttacaaatc aaagagtaaa
    86881 gatttattta tttcaaatat ttgaatataa aataaccaaa cgatagaaag gcttattcta
    86941 catcacgtag taatttttct ttcccgtcgt ttggtttttt atttttagcc taattcttga
    87001 ccttttgcat gctggttatc cgtaaaatat tttccagcag gctttccttc caattcagct
    87061 aatttttctt ggatctgacg gatcaccttt tttgcatctt ctggattttc tacaaaatcg
    87121 aatttatccc catccacttg tattttagga catacatcaa aatcttcata ccattgatta
    87181 tagcgggtgt tcaacgtttc ataataggta tataacgtct catcgctttc tagctgttca
    87241 tagtcacgcc cacgtttttt gatacgttct agcatcgtgt ccaaagaaac tttgatatgg
    87301 accatcaaat caggccgttt ttttggagca acatcatcta actcgtttag catcgtatct
    87361 aataagctat cgtactgctg tacttcgata tccgttaccc gacctaaatc agcgtttaga
    87421 tggaacaaca ggctatcttc atagatggat cggtctagca cattgtcatc gttcactaaa
    87481 gcatttttca ttgctaaaaa tcgcttgttc aaaaagaaga tttgcaataa aaaagcgtac
    87541 tgctcaggat ttgaataaaa gagcggcaat acttcgttat cttcgacatt ttcataaaat
    87601 ggtttagaat caatctcttt tgcaagcata tccgtcaaac tgctcttacc tgcaccaatc
    87661 gttcctgaaa tcaaaatcac tgacatacaa cccttcctct tctataagta ctcgcctacg
    87721 taagtttcaa caggcaatgt ttcaaaatca tattcacgta cagcttggtc tgattttaaa
    87781 tacgtatgga gactttgtgt aatcatcaag ttcgtaggta ccgtctcttc ttgtacaatg
    87841 atcatcggtt ttttcaacat agttgccaca cctaattcgt aagccgttcc tggatcgatt
    87901 gtttgatgct caaagtcaag gatagcaaca acaaattctg catttgtcag ttcttccata
    87961 tctttttcgt atacttcctg cgcccatcca gcgctgaata gttcataatt gctttcttgg
    88021 tgatgacgtg gagagtagaa acttgtgact gttttgtttt cctccaacgc tttttcgata
    88081 cgacttactc gatcgatttg ctcctctgaa aaaaatggtc ctgctaaata tatttgactc
    88141 attattttgc ctccttcaat aataactgat ttttaataga tactgctcgt aattcattga
    88201 ccagttccaa tggattgttg gaaaagatta cttgatccaa ccatttttta tccataaaat
    88261 cctcttttgc aaaagtttct aataattgtt gcaagccgct gtaataaccg ccaatattca
    88321 atattccgat tggcttgtcg ggcgtcagac cgattgctat ccaagaaaga agttgtgaga
    88381 attcctccaa tgtacctaga cctccaggga aaacgaggac agcatctccc ttttcaaata
    88441 ataatacctt tctttcatcg atcgtttctg taggaataaa tgtagtaaca tcttttccag
    88501 gcaattcagt ttcaaaaagc ccattcggat agatacctgt gacttttccg ttattttcca
    88561 gtactgtttt actaatcact cccataatcc cggagtatga accaccgtaa accagttcga
    88621 tttcttcttg tgccatgtat tttcctaacg tttgcgcaat aaatttgtaa ctttctttat
    88681 taccaaaacg ggaaccgcaa aaaacagtaa gtttcataaa aaaacactcc ctaactcaaa
    88741 agtctatctt cattctacac gtgttttttt aaaataaaag actagatttt gtagtttttt
    88801 agtggtatat aggatagacg ccactatata tagtatttag aaaaaaatca tttttcagcc
    88861 attttataga taaaacaaaa ataaataacg tgttttcatc gatatgaaat gacttactta
    88921 tagaagatac tgggatttcg tcctatatgc caataacgtg tattatttta aacaacaaat
    88981 acttgtttct tttattaacg aaaaaatcat tttgttctcg tgttatgttt cactgataaa
    89041 tgatgtttct ctaaataaaa aagccgacga actaaacgat caaaatttga tcatttttgt
    89101 tcatcagctt ctcctaaaaa tctttttgtt aacgataaat agctggattt gtaaaaatat
    89161 cacttgaatc gtcactgctg gaagaaaatt cagtgataac cgcacctgtt gcgcctgcct
    89221 ggaactagtg tttgatattg ggctcgaacg tgtactgatc tctagcatga agaataattt
    89281 ctttttttac tgtataataa ctttctttcc tttttggaat agtacaggaa agtttttttg
    89341 tttcctttcc ttcgacataa ggtataccag accctttcga caacgaaagg ttctcatttt
    89401 tccttcatcg tcatttcaag gagggtgccg atgctctgga cagtttcgat cgctcctaaa
    89461 ccaaaatctg tatattcgat tctttctaac tctgattctt tcataccatt cctgtctcaa
    89521 ggtacatcta ttgtactttt ttcttgtaat ccattctgcc tctcctaact aattgtcaaa
    89581 tcatcccaag atatgtcttc ttcctctttt tcttcttgga tgatttctgc attcggatct
    89641 actggttttt tcaataataa aatggttatt cctgtgacaa aagaaccagc taacaatgca
    89701 ccaatgaatg cccatggtct ggtcatcgta gcgactgcaa acattcccga tgccggaata
    89761 cggctatctg cgccccaaaa catgcttaat ccgccaccta ctgtcccacc gactcccgtt
    89821 gctatgacat tgcgtgccaa gtcgttcaat acgataggga aacatccctc tgtgatctga
    89881 cagatcccca taggaaaagc ggtcttcaat gtatcgattt cttgacgatt gagtatattt
    89941 ttacgaatga ttttccctaa gaaataagcg atcgtcaagc cgaatggggt taccatcgaa
    90001 gctaaaatca atacagtgat tggttcatag attccttctg aaaatcgtgc cacaccccct
    90061 tatccagaat aaatggtaat ccagaaacag ccgtgtatct gcggtaataa gcctaaccaa
    90121 acgaaaaata tgagaagcta tttttgtttg gctgttctta ttacttgatg cagggcagct
    90181 ttttcacaac ctcttttttt atttatgttt cataatcaat atggtaagga tgcagctccg
    90241 tatggtagac cgcctccgaa tattcaatca tttccccaat ttgcgtagac gatttccgta
    90301 tccgtttgat gccgatctgt gcgtctgttt tcagaattcc ttgttcttct tctgttaaaa
    90361 atactgccga gaaatcatca gaaaatgagt caatagtata tccttttttc gtcagcaaac
    90421 gatacaaaga ttctttgcca aattcttctc tgctgaattg catcatttct tgtggaagat
    90481 aatgaacaaa ataaatataa ggctgattgt tcaaataata taagcgctta aaacaaacag
    90541 cttgctcacc gaaaaaggaa aacaaaggat cttccttctt tatatggacc aattgcaaat
    90601 ccagcgtttc tttccggact tcatatcggg agttctccaa gatttgcgta aagcttgccg
    90661 ctttggataa tcgattgtaa ggacgattgc ttagaaccgt cgtcccacga ccacttttct
    90721 ttgcgacata ttcatctgat gccagcagtt cgattgcctt tcggacagtg attttgctga
    90781 cttgaaacag ttcttctaat tcactttctg tcggcaacat cgaaccgact ggatattttc
    90841 ctgagaaaat atcttcttta attttatctg cgacttccaa gtatagtaca cgtgtccttt
    90901 tcataacgtc accctttgct ttactattac taaaagaata gcacataaaa aataaaaaaa
    90961 gaacacaaat cacatgtgag aagtgtgttc tttttcattc agctgcttta attacaagtt
    91021 tacgccattt gaggcaatta cttctttata ccaatcaaaa gattttttct ttgatcgatt
    91081 cagtgtccca tttccttcat cgtctagatc cacatagata aagccgtaac gtttactcat
    91141 ttctcctgtt gatgcactga caagatcgat acatccccaa ggcgtatagc ccatcaaatc
    91201 tacaccgtct gctactgcat tagccatcgc ttcgatatga cgacgtaaat aatcgatccg
    91261 ataatcatca ataatcgtgc catcctcttc catatgatca atggctccaa gaccgttttc
    91321 aacaatgaat aatggtttct ggtaacgatt gtataattca ttcaatgcga ttctcagccc
    91381 ttctggatcg atctgccagc cccattcact tgcctcaaga aacggatttt ttactcctcc
    91441 cagcaagttc ccttctgaag ttgctgcttg tggatcagtc tcattgattg ccgtagacat
    91501 ataataacta aatccgatgt agtccactgg atattctttt agcaactgga agtctttttc
    91561 cgtttgctct aatttttccg gatcgactcc atatttttta tgggtacgcg ctgtgtatgc
    91621 agggtattct ccacgtactt ggacatccgt gcagaaaaaa ttgaattctt ggttttggat
    91681 cattgttgct gcctgattga ctggattggc atcgatgctg taagttgttg catagataat
    91741 catgcagccg atttggatat ccgaacgcaa ttcgtggccg atttttacgg ctttgctact
    91801 tgcaacgaat tgattatgcc atgcttggaa aatattttgg tactctcctg ctccattgct
    91861 ttttactaat ccttgactta aagctggaaa gtgaaaggcc gaattgattt cattgaaagt
    91921 catccaatat ttgactttac tgctgtatct ctctaatact gtctgagcaa atcgttcata
    91981 gaagtcgatc agttttcgat ttttccagcc accgtattct tttgccaaat gaagaggcat
    92041 ttcgtaatga gaaatcgtga tcacaggttc aatatcatat tttaagcact catcaatcag
    92101 ctgatcataa aattctaatc ccgcttcgtt aggagtacct tcgtctccat ttggaaaaat
    92161 tcgtgtccag gcaatcgaaa aacgataaca tttgaatccc atttccgcaa acaaggcaag
    92221 atcttctttg aaacgatcgt aatgatcgat tcctcgatga ttcgggtaaa tatatttttc
    92281 ttgatcaatc gtccagtcaa attcttcact gccgataatc gcaaagcgct gcttacctcc
    92341 aggcatagca tctgcaacgg atagtccttt tccgtctcga tcataagccc cttctaattg
    92401 atttggcagc agttgctcca ccccataaaa atttttctga aaaacgtgat tgcatcctga
    92461 tttcctcctt attttacaat tgccagaaca tcttcgtttg caataatctc tttttggtct
    92521 aattcaagta tatcggcaaa tgcatcagta ttcgtaatga caactggagt gattacgcta
    92581 tagccagctg ctctaattgc ttcgatgtca aaacgaatca ataaatctcc tgctttgacg
    92641 agatcccctt gtttgactaa gatctcaaag ccattcccat ttaattctac tgtatccatc
    92701 ccgatatgaa tcaaaatctc cgctccgtca gtcgttgtga tccctacagc atgtccagtt
    92761 ggaaaaatag tcgtgatctc tccgtctgca ggtgcaacta gttctcctac ttctggatca
    92821 atagcgatac cttttcccat cacgccagaa gaaaaaactt ggtctggtac ttcactcaat
    92881 ggcagtactt tacccgttaa aggacttttt aaggtatgcc gtgctgaagt aatcggttct
    92941 cctgcattcg catgtttgtt ttctaattga ttgtcttgtg tttgttcgtc aaatcctaaa
    93001 atcaatgtac ctacgaatgc aagaacaaaa gcaattcctg tagctattac tgctactgtc
    93061 acatttgact ctacaccatc caccgtatta atgaaagtcg gaatcgtcaa taagctgacc
    93121 aaactgctgg agaaagcttt tactccggaa aatccgataa tagctccacc aatacctcca
    93181 gaaatacaag cggcaatgaa tggtttcttc aaaggtaatg tcacaccata cacagttggt
    93241 tcagtgattc caaataacga agtcactgta gaagaaatcc ctaatgctcg aagtttcgta
    93301 tcttttgttc gcaatgctac agctaaagca gccccacctt gtgccaagat ggctggaaga
    93361 agcattggca tcaatacatc aaacccatat tgttcgatat tcaaaaacat gatcggtacg
    93421 aatccccaat gcatgccgaa catcacgaat acttgccata aacttcccat gattagacct
    93481 gctacgattg gactaaatcc ataaatcgag ttgaagagac cgcctaaagc attaccggca
    93541 accgtcccga ttggtcctaa agcaagaaat gttaatggaa ccatcactac taaaacgaca
    93601 agcggaacta aaatcatttg cagaaattgc ggaatcactt tttttacgaa tggctctaat
    93661 ttactttgaa cccatacggc tagaatgatt ggtatgacag aagaagtata accagatggt
    93721 gaaagaatca ctgggatccc aaagaaactg atagcttctc ccgcaccagc aactgctgtg
    93781 atagctggat acacaagtgc catagcaatt gctactgcta aaaactggtt ggctttgaac
    93841 tttttagctg ctgtaaaagc aagcatgaca ggtaagaagg taaagacacc atctgctgca
    93901 gcaaacaata tttgataagt accgctatca gctgtcagcc agcccatcac cgttgccaat
    93961 gataagaatc ctttcaatac cccggcggct gccatcgccc ctagaaaagg tgtaaatata
    94021 ctagagataa tatcgatcag acgattcaaa atatttttgg actcttcttt tccatcctcc
    94081 gaaactgcaa gaccttcctc atccacgatc gattgataaa catctgctac attactgcca
    94141 atcactactt gatactgacc gccactttgt acgacttgga tcacgtccgg gtcttctttt
    94201 aacttttgcg tatctgctaa agattcatct tttaatctga atcgcaaccg cgtagcacaa
    94261 tgtactaaac ttttgacatt cttttgtcct cctaccgctt cccatacacg acgaccaact
    94321 gcttgattat ccattgtttt ttccttcttt cttttttatt taaaaaataa aaacccagat
    94381 tgaaaaaaac agtcacaaac attcgtgaac ctattttttc aatccaggtt ttgcctgcca
    94441 tacagtaaca atccttatga ttggatgctt tttttctcac ttactactct ttgaatatga
    94501 atcgttaaat aaatctgctc tgcgatcccc atttcctgtt tttgcgtttg tcgaagatac
    94561 tcattgatcc gttcgacaca atgaaacgct tttggatact ttccttgaac taatgcgtag
    94621 agaaattcat cttgctcgtc agatccttcc cctttgagat aacgctgggc aaaaaactgc
    94681 agatgagtaa tgatacgctg ataattcaaa gattcttcat cgaacacgat gccgaagaat
    94741 ttactgatga tactcagtat atctcttacc attgtggtag cggtcatcgt cacttgcatg
    94801 tcttcgtttc cttgttggct attcacaaaa tgaaaggcaa taaaaccggc ttcatcctca
    94861 gaaagttcca cacccgtctt ttgtttcacg aacaaaagag cctctttcgc tgcttgatat
    94921 tctttcggat aaaatttttt tgtttcaaat aataatggat taggcagttg gatattttct
    94981 tttgctcgtg tgatcgcata atgaagatga tcggtcaatg tcagataaat attaggcgaa
    95041 aattcaactt ttagtttatc ttcagccagt tcgactactt gtttgaccca ttcgatctcc
    95101 tctgccggaa tatcagccat cagctgctgg aattggtttt tagcaaaaga atctcttaaa
    95161 acaaattctt tttggaccgc ttctggcgaa atctcgtccc caatcttttt ttgaaaagct
    95221 agtccttttc ccatacaaac gacttcttcc ccgaatccat ttttcgaaat gacgacattg
    95281 ttattcaaaa ttttatcaat tttcattttg cttcgccctc tcaagaaaaa taaaaaaacc
    95341 tagaattcgc ctactgtttc ttagctgaat tctggttttg cctgccgtac agtaacaatc
    95401 catttcttat tcaaaatcat cataccatcg aatttttatt tatgcaagcc ttttcatata
    95461 aaaaataaaa aaactggaac acaagtctat ctagaaaaca accaaatcag agatgcacct
    95521 ctttgcgttt ctcttttttt cagcaaattg gtttttcctt atcgattcat atcctttggc
    95581 tgtttttaat ctgtaacgac ttatgtccca gtatcctaaa atgtttttgt ctctagattg
    95641 aaagcagatc tcatatcatc tgtcgcatct tttatcgatg taacactttc cagttctcct
    95701 tgtacaacta gtcgcgtgac ggcgtccatg tcgccacaag taattagtgt gacaatttct
    95761 tttccctcga cttcattcag taattgggta tctgtaggag caactttttc tttaaaaaat
    95821 gttttgtatg tatacacatt ttctaaatct gtcaaataga tcttggcacc catctctaaa
    95881 ttttctagcg gtgtaaacag caattcaggg ttcgttgcac gatggcttgc taaggcataa
    95941 tttccttttc ccatttcttg atctggagat aatgttcctg ctccgtaaag tagtgacgta
    96001 ttatccaagc ctttgaaaac cggtaaattg attgaaactg aagggactgc gatactagca
    96061 atcactggta gatctgttcc tctcatttgc gacctcatga ccccttctgt cgtcattggt
    96121 tctaccgcat caaagtcaaa actgacatct ttatcgttat tctttttcag atcttctttt
    96181 gttacattcg ctatagcata tttatctcct gtctctctga caaaataatc cttgatctgt
    96241 tcattgaaaa tcaaagctag tcctactaat aacaagagga acaagaggat attgactagc
    96301 catctttttg cttttccttt ttttttcatt ttctctccct ccagactcat tttactgttt
    96361 ttcttttgct ctttccaaca gccgaatgac acatttctac aactctgtgt atttttttcg
    96421 tacacctgcg cttttttcta caggatattt caaattattt ttgatcaatt tttcttcaat
    96481 gatctcatct agatccaggt gaaggttgtc tgccatcatg tatgaataga tcaatacatc
    96541 taccagttct tctttgattc gttctaattg tgtttctttt acttcttccg gcgttttcca
    96601 ttgaaaaagt tctaacaatt cagatgcttc caaagaaata gagatagcca aatctttttc
    96661 gttatgaaat tgtcgccaat tacgttcatc tctaaactgg ttgacttttt ccatactatt
    96721 catttgcttg ccttcttcca atcacttctt acttgattaa tcataccatt tttttacata
    96781 aaaaatagat gatgctttta aaaaaactcc tgttttcttt tatttaaaat aaatgtcata
    96841 gaaaatcaat aatttaggta gccaccatgt gtatgcagta gcgtgtcttc ttcccttgag
    96901 gctttttgtt tttcgatacg ttcttcttcc caaacagaca acgctactag aatctctctt
    96961 aatgattttc cttcttcggt gagcgagtac tctactttag gcgggacttg gttataggct
    97021 tttcgatgga tactttcatc ttgttctaac tctcttaact gctgggtcag catttttttt
    97081 gtgatcgtag ggatttgctt gcttctccac gcctaaaata agcgatattg ctcttccctt
    97141 tatctggtgt aagcaaagca gttagcattt tgacgatcgt gggttccgct tttcacttct
    97201 tatctactta gtatcatgaa gtatactttc gtactaatac taagtagcgg aagtgtcaac
    97261 tactttgttt aactacatag caaaagaaac agaagggtga caacggtcat cacgcttctg
    97321 tttcttttga atatgctgtg ttgttgtctc tatctccgtg tagactttcc tcaaacttat
    97381 cctttgacag taagtcagta ggctgatttg ctctttctag atgccagata catttctaca
    97441 aaaaaatagt gattctgttt tgaaaattcg atttttagtt ctgcattttc gtaaacatcc
    97501 aacatttttt tcgcactgta tagacctaac ccgccatttt ttttagaggt ttttcctctt
    97561 ttgaccatct ccgatagcgt caaattcgtt ggatttgcct tgttcgctat actaaaacgt
    97621 gatccctctt tttcttccag cagattgatc gtaatcggac tctgatcggc tacacgatga
    97681 tcgaatgcgt tagaaataaa aatagataaa cagcgaataa aaacaaccag atcaatcggg
    97741 attgttttca cttcgacagg aataactact tggatcggga ttttctccga ttctgctttt
    97801 tctagaaatt ttaaaaagac acccctgaca gctggggata caatatttgt tagctgttgt
    97861 atttgcggtt tttcaaaaat agctgcagaa tgatcttcta atatttctaa aaattccaac
    97921 gtttcttttt tattttcctg aagagtaatt tttaatgaaa acagtagact tttataatca
    97981 tgtttgaatt cctctagatg atggtaatat tcttcattta tttgatacag ttgaagcgat
    98041 tcctgatgtt gtctttcttt tacttggaaa ctgatcaaca taatggaaaa aaacaaagaa
    98101 aaaaaactga tgactatcga caaaagagat agaagcagat aattagatga gcggaagtga
    98161 acacttccca ataccaagta aatcacgccc cagcttaata aaatacaaat acctccaaaa
    98221 tagtgttcag ttggataagt aaaaagcaag ttgagaaatc tcgtctgttt gtctatactt
    98281 tttactaata gatagaaaat aaatgcgata agtagtgcaa aaaaacttgc tgttccaaga
    98341 tgtctctttc ctaaataatc catcagatca aaaaccagaa aaaagctgag tccagtgata
    98401 gcaaaaaaaa gattactgat caaacagctg ataaacaggt ttttcgtagt aaaataaaaa
    98461 agaaacatca ataataagcc aactaggtaa ggaaagctca ctttagggat aggaagtaaa
    98521 agtgtcacca ccatcaaagc tatacaacca aagctgtttt ttactagcag ttgtttcgaa
    98581 aagaataaat agatacctaa atctaaaatc aaagtaaagg tcaaataaag tgtcactgtt
    98641 gcgaccatct tattcctcca ttgttttgtt tcaaaatgta cacatatttt tttaatagga
    98701 gcctgcatat gaaaaagtat tttatcatag aagataacca gtttcacagc gaatggatca
    98761 tcagagaatt ggtcaatcat catatcgaga atatcgtgca gctcacttct atctctcaaa
    98821 tcaatcagtt gatccagttg ggcactattg ataatcacga tgttttcttt atcgatatcg
    98881 acttgaagca atcactcaca ggtattgatg tcgccgaaca aatacgtaaa aaaaatgcac
    98941 atagtaatat tgtttttttc accgcttata cgaattttgc agtagagatc atcaatcgga
    99001 aaatccttcc gattggatat atcagaaaag acaggaattt atctgaacaa attcgtcaag
    99061 tgctagaaca gatcaattgg aaagaacagc agatcgtaaa tgtcgataaa atctttattg
    99121 atcaaaaagg tggaagtctc gtcctgtatc ctcgggaaat tttatatatt gaaagtatca
    99181 aaggtttgaa aaaccaagtt atggtcaaaa caactacaga agataaatta gtgaatactt
    99241 ctttaaaaca attgaagaca gagttagaaa agtatgctta ctttttactt ttaaaatctt
    99301 actgtatcaa cttatcgcaa ttgcagaaaa ttgattctgc tcattatgtg ttagaatttt
    99361 tcaacggtga ctccttactc gttggtcgaa agatctttga aaagacaaag gaacgtttcc
    99421 atgacttcca aaaaactgct tcgagttgat gaataagagc tgagacgtaa gcatagcaga
    99481 tttcagggag tgggccttga atcggctcca ctccctgaaa tcgttgatat gattttacgc
    99541 ttcctcttct gtaggagcat ctgttaacga ccatgtgaat gttgaaacgt agttgtctac
    99601 agcataattg gatacaggaa caaataattc cactgattgt ctcccttgtt ccacattctc
    99661 tcctaatgaa taaatccatg tgccaatccc ttcatttgct cctgcagtta ctagatctac
    99721 tgcctgatct gctgggattt cgattccttc agcgccagtt ccagaaacgg tagatggcat
    99781 tccactgcta ttagttgcgc tatttcgaat cacggcgttt ttgaatttca cctttgaacc
    99841 agttagttta ttcgtatcag atgttgtacc aataaattct gttcgtttga ctgataattt
    99901 ccaaccggca taatttccgc ttttatccgt tacttgtacg aaattctgta cttgtgtttg
    99961 tgctccagta ctgtccgttc cgctttgtaa tgcagcatat actgtttttg ctgtacctaa
   100021 cttgattgtt ccaaaatcaa gatctggagc ttggtcaatc gtcagtaatc cggatgttcc
   100081 ctgatttggt tcgtcaggtg taaaaggagt atcaggatca tttggatcaa caggaggaac
   100141 tggaacaacg tcttcaggat ttgcagcatc tggtttggtc acagaaatcg ttccttctgt
   100201 agtggctgag ctcttattct cagcaaaaac actttgtgta cataataata gacttccagc
   100261 tagaacggta cttaatgcaa ttgttttttt catttctttt tccttctttc ttttaaaata
   100321 aataatccag caaataagcc aataagaatg actccaacaa gtatcagcca tcgccagtca
   100381 aatgtttctg gctgattttt taaatcaata tccttttcat tcaattggtc cgctgcatca
   100441 tcagttattt caaaatcggt atggagattc cagcgttttt ctttccaagc acccttcaca
   100501 accgcttgat aatgtcccgg agctaatttt tttccttcta atgggacaag taaatcaaaa
   100561 tttgtattgg gtgctacatc tattttttct ttttttattg aaaggtaagg ctcttttgtt
   100621 tcttttttgt agatttcaac cgatgtagtc aagccgaaca tataagaagc atttggattt
   100681 tgaagattcg ccttaatcac atttcttcca tcgctttgat ccgcataagc tttttttaat
   100741 ttcaaatctg gggaagactc tttttcgcta tttcaaatca agattgcttt cacttgagaa
   100801 aactgattga cgacaccaac tgtacttttg ttagaaacgt tctctttttt ttcttgaaac
   100861 gtgatccctc ctgcgaccac accagccagc tctttttctg gcgctttcag tgaaagtgtc
   100921 tcagtgaccg cactttgagg aggaacagtt atttctccca ctgtttttgc taagtttttc
   100981 atatcataac ttaatgtttc atcaaattta ctttttgatt ctccatattc gatcacaccg
   101041 tttgaattcg tcgtagcgga gtggatcaat gtctcaactg ttactgattt atctgttcgg
   101101 ttaaagaccg tgtaggggat ttcctgtgtt ttcccaggct ccatccttac atttatatat
   101161 gttttgttct tatcaatctg attagccggt aattcaaaat ctaccgcaaa attgaattcg
   101221 gaggcatgga caggtgtctg ccaaaggatg aatccaagga gaaggatcat aagtaaagag
   101281 cagttgtttc gatgactttt attccatatt cgattcatca atcatcctcc ttgatcttta
   101341 ttctgtcggc gcatctgcta atgtccatgt tatctctgct gagtaattac cagctatctg
   101401 attttctttg gttaagacaa gtttaaacgc ccgaccgtta tttaaatatt ctgaataatc
   101461 tgcttgcaca ttcgttgaat tttgtcctct gacaatttcc agttcttctt cattcactaa
   101521 ttgatactcc tctcctttct tgaaatatag gacatcctgc atagaaaatc ctgcatcatt
   101581 tgtgaaaggc tgagataatt ttatcgttaa gatccacgga tttttcgttt ctcgctgatc
   101641 ataaatccat aatttttcct gtatatccat ttggccaaat gcttcttgtg tcaaaccagt
   101701 tgctttgatc tgaccaaaat cgagtttgga aggggcaaga aatgagagac caccttctac
   101761 tacgatcttc gtagcaggtg caaaaggcgg ggcatcatga taaacaactg gcgtatcact
   101821 tggattgtga ttcccaattt catcgttggt acttggcttg ttctgcacac ccttagcagt
   101881 agcttctcct gcttggtcgt ttaatacaat ttctaataca tctcctgcaa aaagttgatt
   101941 ttctgggata gaaagaacaa attcccctgt atcatcaata gttgtttctg acaaaacagc
   102001 ttgatttttt ttcaatgaaa ccaaggctcc tgcttcacct gtacctgtga tcgtgcgaga
   102061 agctgcattg atcaatgtgg tacttaaatt agcaggttca ggaggaatca catcgactgt
   102121 cgttttggca gagtccagtt ctgtcacttc ttggccacct cttacttttt tagcagcaac
   102181 aacttgcact tgatcctccg tttttaatct ctcatcattg ggtacttgaa cttcgaacaa
   102241 gccgccttgt tcgccttctc cccatgggtt atatcctgcc ccttcatttt catctgtttg
   102301 tccttgcgtg agagcagtaa tttctacaga tgatttcgtc gtatctgcgt aagtaatacg
   102361 taaagtcact tctacttcgc ctgtccaagc atctcttggc tttgcctcga caccttcggg
   102421 aacaacgaca tgcccataga tttttttatc tgcattcgtt ggcactctta aggattcaat
   102481 catcgggagc tgattattgg cactgattcg attataattt ttcattccgg cacctgtctg
   102541 agcaaattca tttgttaaac ctgcactagg gcttgatacg aaattgccta agtcggtccc
   102601 attgatcgat aagtctgtca tatcagaaaa ataatccggg tctttttcaa agttatcgaa
   102661 tgttgcgcct gtttttcgcc ataaagcgat ttctgaatgg gcgatcttta aagaagaatc
   102721 tccatttcct tggaataccc agccgcctat gccattggtc tcgcttccaa tccgtttgtt
   102781 ttggaaatca aaataggtag gagattctaa gtccacattc aacacatccc cactgatgat
   102841 gccggtctta tcttcccctg ttttcccgac catgactaaa taagtttttt cacctgccgt
   102901 aaaatttaaa tcaatatctc cagttgtatc tacagttgct ccggaatctg cgcgtatatc
   102961 gatatttgat ttttctccag tgactgtaaa atcagctgaa cctggacttt ctagaaaacc
   103021 agaagcgtca taaaattgga tcgcttgatt tccttgattg agtctgttca cgtaagattt
   103081 gccatcacct gtatttctta ccctcaatga gcctccattg gttactgtca gcttttgcgt
   103141 accattctca aaacgaactg cgctggaacg cccactctgc ttatcgatgt cgataactga
   103201 tccggctcct tctacgatca aagaaaggcc ttttcctaca aaacgcatcc cattgttccc
   103261 gggttgatcg tcatctccag ccattttgac cgagatttgt ccaccacttg atacatggat
   103321 ttgactagaa tctccttgca agcgaaatcc gcccgtagtt gctgtattga tggtgatttt
   103381 cccaccattc gatacagtga ctttcgatcc tgaacctctc atttggatga ttccgcgatt
   103441 gttgtcattg gtaatattga tctttgtatt taccgaaaat tcgcttcccg aaccactgac
   103501 ttcaaacatg acattaccag gtagcgtatc gactgcctct ccttcatcgc taacgccatc
   103561 tgcccgatca taatcaagag agacctttga accgcttaag atatggattc ctggcgctgt
   103621 ttttccacta ccagtctcat ctcctgaatc tagaaaaccg tagaatttcc ctagatacgg
   103681 tccataaagt tgactaccat tgatcacatt caattgatag cttctacaaa aataggcttt
   103741 acccggagcg gcattcagtc cttccttcac tggttggaca tccaacacac cggaaacacc
   103801 atctaatgtg acagttgcac gaggagcgta aatcagtcct aatttggacc catcatacaa
   103861 atcaagtgtc ccggtaaatt ttatttctcc cgtaaaatga tatctgcttc cccaaaaatc
   103921 ggtcatataa gcaatgataa tggcatttcc atcgatattt ggtgtcaatc cacctggatg
   103981 tgcagctgtt cctttaaaat tctggaactc gatcgactga ggtatctcat tgatataaat
   104041 atggtgtgtg ccgaaattgt gagcgaatcc accaaaatca ataacgatat ctcgtttgat
   104101 ctctaattcc ctgtctaaag tcaaaggctg aatcagtcgg atcttagtta ctgattcgtc
   104161 tgcgagaagc tgcgccagtt cttctgttgt ggcagcttcg ctgtacccat ccgctgaaac
   104221 agctcttgcc agtgccgctt cactgctatc agacgtttgt tcagctactt ctgaggtctc
   104281 acttgtctta ttttcttctt gccttttatt agtagaagcc tcactttgag attctgtagt
   104341 ttcagaagta atcgattctt ctgaaaaagt agtcttgtca aaactttgat tctctgattg
   104401 cgttgattcg tttgttttct ctacatcggc aaaaacggat gtcaccatca agagagggaa
   104461 gacaaacaaa atcgacgcaa tcagcttttt tacacattga ttcattctcc accatcctct
   104521 ctgacgtttt gacaatttta ttttatcgtt ttaatctatt tccaattgta ctttcatatt
   104581 taaaatatgt atttttatgg aaaaattttt ctattaggtg taaatttctt ttttgtacaa
   104641 aaaaaaggct gtgacaaaag tcttgtcaca gtcccttatc ccgaacaagc ggtgttctcc
   104701 cgccaactcc tcggtcacaa cctccatttt aacaataaac ctgtaaatgt gagggcaata
   104761 ctttgattgt cacaggtaat ttatcccctt catctccatc aacattcgtc gtcaattctt
   104821 cctcatcagc taatgacaca actaattgct cacaagtaag gtaggctaga tttttcgtag
   104881 attcatctac tccttttaat aggtctggca atgttttaag cgtatcgatc aaagaagaat
   104941 cttttaaata aaccaaatgg agcttaccat catccacttt tgcatttgga agtaatgttt
   105001 caaaaccgcc gactgagtta gttagtccta tcagcaaggt actgctctca atttcttcct
   105061 tctttccatc aacttctacg tgaaacgagt aggattgtgt ggaagctaac tgtttgattc
   105121 ctgacatgaa ataagctagt tttccaaatt tcgtcttctt ctccgcatct acatcattga
   105181 ttgattcagg gatagagcca attgcgacga cattcataaa atagtcgtca tttatttttc
   105241 caatatccaa tggcttgact gattcaatcg aaaaatgatt gatcgcttcc tcaggttcta
   105301 gcggtatccc taatgctcga gccaagtcat tcaccgtacc caatgggaaa aatccgaaat
   105361 ttggccgatg ttcttgttca gcgattccac tgattccttc gttgactgtt ccatctccgc
   105421 ccatgacaaa cacactatga tacccttccg tagccgcttc gcgagtaaag ttttttgcat
   105481 cccctgcttt ttttgtatgc aagacgacca cttcatcaaa caccgattcc aattttgcta
   105541 tcgctaattg ctcaaattcc tttgcttgtt caccgcctga actggggttt accactaata
   105601 aaactttttt catcactttc tttcccttct gattgatttc tttaatataa cgatagcata
   105661 aagaaaaaaa ttaggctgtg atgaagtact gttcatgaaa cattcattta ttttttgaca
   105721 agataaaaca tccatactat gaaactgagg aaaattaaaa caatgatata ggaaataaaa
   105781 gaaaatgata ggcattgtat acctaataaa gtaaaaatct taggtggcag ataaaaacac
   105841 aaaaatagca agagaatgta atagcgtttc ttccactttt tgttatcaga ccttatagcg
   105901 atcagaggaa taccaaatgc ataactgaaa aactcttgat gtactgttaa tatgtcacgg
   105961 ccttgaataa taaatgcgac aatccccgct ataattagtg tgcctaacac caaaacggaa
   106021 aattgatgaa tatattttat atacaaatga tccattgtac ttcctgcctt tttatttgtg
   106081 agaaaaacaa atccgtatac gtgaataact tctagaaata aaagaaattt gcaaaaccac
   106141 tccatttatc tacttctacg tgcatttttt gatattgttt tctttattta agattataca
   106201 gaaaaatatc tagggtcgct ggattctaag taaaaaaaat ttttaaaata aaaagaacta
   106261 aatcaagtag taattaaact actgttgatt tagttctaat aaaaagattt agatgaacag
   106321 ttttattgat ttaaatagtt catatttttt atttataccg cttatttact acttgctgta
   106381 ctagaatctg aagtgaatgt actcaaaaca ttttcaaagt ctttgtcttt gatttttaca
   106441 ttagcgtctt tcaatacttc gccaattact ttattctgga aggtactgtc acttaatttt
   106501 gtgtctgttg caatttcttt caattctttt ttgtatttat ccatgtcgtt gcctttgttt
   106561 tggtttttca ccattttaac cacataatat tccgtagtat aagttgaagc attggtagaa
   106621 gtgatcacat cagaaacttg accatctttc aacttaaagg ctgcttcttt gacttctgcc
   106681 ggaaccgttg tagtagtgga atcaaatttc acttttccgc catcttcttt tgtcgtagta
   106741 tcagttgact tgtctttggc taatttagag aaatcgtctc ccttatcagc agctttcttc
   106801 acatcttttg catcatcttc acttgctact tggataattt gagcttccac ttctggatgg
   106861 aaagattccc aagccgtttt taaatcttca tcggtcaatt tgatatgttt ctttagacct
   106921 tcttgaaagg ctagactttg tttgatactg tctttgaatg tttgttctgt gtaacctgca
   106981 gatttcaatt gtgaatcaaa tgaatcaccc aattgtttct ttgtttgatc atattgagaa
   107041 tcgatttctt tggttgatac gtcatctcca tatttatctt caaatacttg ataaacgatc
   107101 aactgttgca cagcggaatc tgctccttgc atttttttca agctatccat tacttcttgt
   107161 tcgctgattg taccgccttt ataactaacg gctgtttttt caccggcatt cgtacagcct
   107221 gacaataagc cagtgcctag tacgatggca agtgctaaaa atcttttttt catttatcaa
   107281 ttctcctact tttcgttttt tgcgaattgc taaaaacaaa ggtgttcaag atgaaaatca
   107341 tcaagaacac ctttactaat ctgctcgata cgtcctgaat agatataagg ctacacaatc
   107401 cagaaagttc gctcagcaga ataaatgtca agtagcacat cacaccttaa tatactactt
   107461 cttttgttac cgtttttcaa gtctatcttg cgttccgtat ttaacgtaac taattcttag
   107521 aacaaatgtt atcgattttg tttttcttct tccgctgctg ggatattcaa atcagacact
   107581 tttatgttcg attttccaga catttttttg ttgtttttat tat
//
LOCUS       DAFEKH010000002        83151 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.002, whole genome shotgun sequence.
ACCESSION   DAFEKH010000002
VERSION     DAFEKH010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 83151)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 83151)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83151
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.002"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..203
                     /locus_tag="LP386_000098"
     CDS             <1..203
                     /locus_tag="LP386_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HBL1917370.1"
                     /translation="TARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSADKKVL
                     TPAQRLGITDKQFDWKDIIYFK"
     gene            complement(275..772)
                     /gene="dfrG"
                     /locus_tag="LP386_000099"
     CDS             complement(275..772)
                     /gene="dfrG"
                     /locus_tag="LP386_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HBL1917371.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            1134..2174
                     /locus_tag="LP386_000100"
     CDS             1134..2174
                     /locus_tag="LP386_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBL1917372.1"
                     /translation="MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRK
                     KIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQ
                     MEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLP
                     LGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVS
                     TPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIVNTQ
                     LKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRLNSR
                     IDKVRYMFNKIT"
     gene            2272..2460
                     /locus_tag="LP386_000101"
     CDS             2272..2460
                     /locus_tag="LP386_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HBL1917373.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(2518..2871)
                     /locus_tag="LP386_000102"
     CDS             complement(2518..2871)
                     /locus_tag="LP386_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1917374.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            3402..3824
                     /locus_tag="LP386_000103"
     CDS             3402..3824
                     /locus_tag="LP386_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBL1917375.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            3821..4051
                     /locus_tag="LP386_000104"
     CDS             3821..4051
                     /locus_tag="LP386_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1917376.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            4549..4749
                     /locus_tag="LP386_000105"
     CDS             4549..4749
                     /locus_tag="LP386_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBL1917377.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            4776..5969
                     /locus_tag="LP386_000106"
     CDS             4776..5969
                     /locus_tag="LP386_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL1917378.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(6037..7602)
                     /gene="guaA"
                     /locus_tag="LP386_000107"
     CDS             complement(6037..7602)
                     /gene="guaA"
                     /locus_tag="LP386_000107"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBL1917379.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(7661..8584)
                     /locus_tag="LP386_000108"
     CDS             complement(7661..8584)
                     /locus_tag="LP386_000108"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HBL1917380.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            8780..9385
                     /locus_tag="LP386_000109"
     CDS             8780..9385
                     /locus_tag="LP386_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL1917381.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            9693..10709
                     /locus_tag="LP386_000110"
     CDS             9693..10709
                     /locus_tag="LP386_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBL1917382.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            10850..12151
                     /locus_tag="LP386_000111"
     CDS             10850..12151
                     /locus_tag="LP386_000111"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HBL1917383.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            12197..12859
                     /gene="deoC"
                     /locus_tag="LP386_000112"
     CDS             12197..12859
                     /gene="deoC"
                     /locus_tag="LP386_000112"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBL1917384.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            12880..13278
                     /locus_tag="LP386_000113"
     CDS             12880..13278
                     /locus_tag="LP386_000113"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBL1917385.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            13344..14426
                     /locus_tag="LP386_000114"
     CDS             13344..14426
                     /locus_tag="LP386_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL1917386.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            14638..16200
                     /locus_tag="LP386_000115"
     CDS             14638..16200
                     /locus_tag="LP386_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1917387.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            16193..17326
                     /locus_tag="LP386_000116"
     CDS             16193..17326
                     /locus_tag="LP386_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1917388.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            17326..18282
                     /locus_tag="LP386_000117"
     CDS             17326..18282
                     /locus_tag="LP386_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1917389.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            18381..19547
                     /gene="deoB"
                     /locus_tag="LP386_000118"
     CDS             18381..19547
                     /gene="deoB"
                     /locus_tag="LP386_000118"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBL1917390.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            19571..20389
                     /locus_tag="LP386_000119"
     CDS             19571..20389
                     /locus_tag="LP386_000119"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBL1917391.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            20406..21113
                     /gene="deoD"
                     /locus_tag="LP386_000120"
     CDS             20406..21113
                     /gene="deoD"
                     /locus_tag="LP386_000120"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBL1917392.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(21411..22097)
                     /gene="gpmA"
                     /locus_tag="LP386_000121"
     CDS             complement(21411..22097)
                     /gene="gpmA"
                     /locus_tag="LP386_000121"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBL1917393.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(22269..22850)
                     /locus_tag="LP386_000122"
     CDS             complement(22269..22850)
                     /locus_tag="LP386_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1917394.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(22983..23666)
                     /gene="rpiA"
                     /locus_tag="LP386_000123"
     CDS             complement(22983..23666)
                     /gene="rpiA"
                     /locus_tag="LP386_000123"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HBL1917395.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            23985..24398
                     /gene="rpsL"
                     /locus_tag="LP386_000124"
     CDS             23985..24398
                     /gene="rpsL"
                     /locus_tag="LP386_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HBL1917396.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            24482..24952
                     /gene="rpsG"
                     /locus_tag="LP386_000125"
     CDS             24482..24952
                     /gene="rpsG"
                     /locus_tag="LP386_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HBL1917397.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            25046..27133
                     /gene="fusA"
                     /locus_tag="LP386_000126"
     CDS             25046..27133
                     /gene="fusA"
                     /locus_tag="LP386_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBL1917398.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            27305..28492
                     /gene="tuf"
                     /locus_tag="LP386_000127"
     CDS             27305..28492
                     /gene="tuf"
                     /locus_tag="LP386_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBL1917399.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            28899..29207
                     /gene="rpsJ"
                     /locus_tag="LP386_000128"
     CDS             28899..29207
                     /gene="rpsJ"
                     /locus_tag="LP386_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HBL1917400.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            29238..29867
                     /gene="rplC"
                     /locus_tag="LP386_000129"
     CDS             29238..29867
                     /gene="rplC"
                     /locus_tag="LP386_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HBL1917401.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            29895..30518
                     /gene="rplD"
                     /locus_tag="LP386_000130"
     CDS             29895..30518
                     /gene="rplD"
                     /locus_tag="LP386_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HBL1917402.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            30518..30808
                     /gene="rplW"
                     /locus_tag="LP386_000131"
     CDS             30518..30808
                     /gene="rplW"
                     /locus_tag="LP386_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HBL1917403.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            30847..31680
                     /gene="rplB"
                     /locus_tag="LP386_000132"
     CDS             30847..31680
                     /gene="rplB"
                     /locus_tag="LP386_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HBL1917404.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            31723..32001
                     /gene="rpsS"
                     /locus_tag="LP386_000133"
     CDS             31723..32001
                     /gene="rpsS"
                     /locus_tag="LP386_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HBL1917405.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            32024..32371
                     /gene="rplV"
                     /locus_tag="LP386_000134"
     CDS             32024..32371
                     /gene="rplV"
                     /locus_tag="LP386_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HBL1917406.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            32385..33041
                     /gene="rpsC"
                     /locus_tag="LP386_000135"
     CDS             32385..33041
                     /gene="rpsC"
                     /locus_tag="LP386_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HBL1917407.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            33044..33478
                     /gene="rplP"
                     /locus_tag="LP386_000136"
     CDS             33044..33478
                     /gene="rplP"
                     /locus_tag="LP386_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HBL1917408.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            33468..33656
                     /gene="rpmC"
                     /locus_tag="LP386_000137"
     CDS             33468..33656
                     /gene="rpmC"
                     /locus_tag="LP386_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HBL1917409.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            33681..33947
                     /gene="rpsQ"
                     /locus_tag="LP386_000138"
     CDS             33681..33947
                     /gene="rpsQ"
                     /locus_tag="LP386_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HBL1917410.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            34005..34373
                     /gene="rplN"
                     /locus_tag="LP386_000139"
     CDS             34005..34373
                     /gene="rplN"
                     /locus_tag="LP386_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HBL1917411.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            34410..34718
                     /gene="rplX"
                     /locus_tag="LP386_000140"
     CDS             34410..34718
                     /gene="rplX"
                     /locus_tag="LP386_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HBL1917412.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            34746..35285
                     /gene="rplE"
                     /locus_tag="LP386_000141"
     CDS             34746..35285
                     /gene="rplE"
                     /locus_tag="LP386_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HBL1917413.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            35304..35489
                     /locus_tag="LP386_000142"
     CDS             35304..35489
                     /locus_tag="LP386_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HBL1917414.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            35525..35923
                     /gene="rpsH"
                     /locus_tag="LP386_000143"
     CDS             35525..35923
                     /gene="rpsH"
                     /locus_tag="LP386_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HBL1917415.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            35955..36491
                     /gene="rplF"
                     /locus_tag="LP386_000144"
     CDS             35955..36491
                     /gene="rplF"
                     /locus_tag="LP386_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HBL1917416.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            36652..37008
                     /gene="rplR"
                     /locus_tag="LP386_000145"
     CDS             36652..37008
                     /gene="rplR"
                     /locus_tag="LP386_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HBL1917417.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            37029..37529
                     /gene="rpsE"
                     /locus_tag="LP386_000146"
     CDS             37029..37529
                     /gene="rpsE"
                     /locus_tag="LP386_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HBL1917418.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            37544..37723
                     /gene="rpmD"
                     /locus_tag="LP386_000147"
     CDS             37544..37723
                     /gene="rpmD"
                     /locus_tag="LP386_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HBL1917419.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            37767..38207
                     /gene="rplO"
                     /locus_tag="LP386_000148"
     CDS             37767..38207
                     /gene="rplO"
                     /locus_tag="LP386_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HBL1917420.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            38207..39502
                     /gene="secY"
                     /locus_tag="LP386_000149"
     CDS             38207..39502
                     /gene="secY"
                     /locus_tag="LP386_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HBL1917421.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            39564..40211
                     /locus_tag="LP386_000150"
     CDS             39564..40211
                     /locus_tag="LP386_000150"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HBL1917422.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            40402..40620
                     /gene="infA"
                     /locus_tag="LP386_000151"
     CDS             40402..40620
                     /gene="infA"
                     /locus_tag="LP386_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HBL1917423.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            40653..40769
                     /gene="rpmJ"
                     /locus_tag="LP386_000152"
     CDS             40653..40769
                     /gene="rpmJ"
                     /locus_tag="LP386_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HBL1917424.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            40787..41152
                     /gene="rpsM"
                     /locus_tag="LP386_000153"
     CDS             40787..41152
                     /gene="rpsM"
                     /locus_tag="LP386_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HBL1917425.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            41180..41569
                     /gene="rpsK"
                     /locus_tag="LP386_000154"
     CDS             41180..41569
                     /gene="rpsK"
                     /locus_tag="LP386_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HBL1917426.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            41649..42587
                     /locus_tag="LP386_000155"
     CDS             41649..42587
                     /locus_tag="LP386_000155"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HBL1917427.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            42615..42995
                     /gene="rplQ"
                     /locus_tag="LP386_000156"
     CDS             42615..42995
                     /gene="rplQ"
                     /locus_tag="LP386_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HBL1917428.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            43267..44106
                     /locus_tag="LP386_000157"
     CDS             43267..44106
                     /locus_tag="LP386_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBL1917429.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMIFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            44082..44951
                     /locus_tag="LP386_000158"
     CDS             44082..44951
                     /locus_tag="LP386_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBL1917430.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            44941..45738
                     /locus_tag="LP386_000159"
     CDS             44941..45738
                     /locus_tag="LP386_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBL1917431.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            45941..46687
                     /gene="truA"
                     /locus_tag="LP386_000160"
     CDS             45941..46687
                     /gene="truA"
                     /locus_tag="LP386_000160"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBL1917432.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKGELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(47020..49689)
                     /locus_tag="LP386_000161"
     CDS             complement(47020..49689)
                     /locus_tag="LP386_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HBL1917433.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDGGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(49927..50115)
                     /locus_tag="LP386_000162"
     CDS             complement(49927..50115)
                     /locus_tag="LP386_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HBL1917434.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            50385..50747
                     /locus_tag="LP386_000163"
     CDS             50385..50747
                     /locus_tag="LP386_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBL1917435.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            50799..52481
                     /locus_tag="LP386_000164"
     CDS             50799..52481
                     /locus_tag="LP386_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HBL1917436.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            52598..54634
                     /gene="recG"
                     /locus_tag="LP386_000165"
     CDS             52598..54634
                     /gene="recG"
                     /locus_tag="LP386_000165"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HBL1917437.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            54683..55684
                     /gene="plsX"
                     /locus_tag="LP386_000166"
     CDS             54683..55684
                     /gene="plsX"
                     /locus_tag="LP386_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HBL1917438.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            55806..56048
                     /gene="acpP"
                     /locus_tag="LP386_000167"
     CDS             55806..56048
                     /gene="acpP"
                     /locus_tag="LP386_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBL1917439.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            56316..57320
                     /locus_tag="LP386_000168"
     CDS             56316..57320
                     /locus_tag="LP386_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1917440.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            57321..58265
                     /locus_tag="LP386_000169"
     CDS             57321..58265
                     /locus_tag="LP386_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1917441.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            58265..59227
                     /locus_tag="LP386_000170"
     CDS             58265..59227
                     /locus_tag="LP386_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1917442.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            59254..60168
                     /locus_tag="LP386_000171"
     CDS             59254..60168
                     /locus_tag="LP386_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1917443.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            60194..61975
                     /locus_tag="LP386_000172"
     CDS             60194..61975
                     /locus_tag="LP386_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL1917444.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            62323..63009
                     /locus_tag="LP386_000173"
     CDS             62323..63009
                     /locus_tag="LP386_000173"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HBL1917445.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            63029..66610
                     /gene="smc"
                     /locus_tag="LP386_000174"
     CDS             63029..66610
                     /gene="smc"
                     /locus_tag="LP386_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HBL1917446.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIETALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            66619..67428
                     /locus_tag="LP386_000175"
     CDS             66619..67428
                     /locus_tag="LP386_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL1917447.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            67439..68437
                     /gene="ftsY"
                     /locus_tag="LP386_000176"
     CDS             67439..68437
                     /gene="ftsY"
                     /locus_tag="LP386_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HBL1917448.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            68624..70891
                     /gene="gshAB"
                     /locus_tag="LP386_000177"
     CDS             68624..70891
                     /gene="gshAB"
                     /locus_tag="LP386_000177"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HBL1917449.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(70980..71432)
                     /locus_tag="LP386_000178"
     CDS             complement(70980..71432)
                     /locus_tag="LP386_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HBL1917450.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            71582..72532
                     /locus_tag="LP386_000179"
     CDS             71582..72532
                     /locus_tag="LP386_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBL1917451.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            72525..73484
                     /locus_tag="LP386_000180"
     CDS             72525..73484
                     /locus_tag="LP386_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBL1917452.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            73481..74236
                     /locus_tag="LP386_000181"
     CDS             73481..74236
                     /locus_tag="LP386_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1917453.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            74259..75212
                     /locus_tag="LP386_000182"
     CDS             74259..75212
                     /locus_tag="LP386_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL1917454.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(75856..76152)
                     /locus_tag="LP386_000183"
     CDS             complement(75856..76152)
                     /locus_tag="LP386_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HBL1917455.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            76507..76863
                     /locus_tag="LP386_000184"
     CDS             76507..76863
                     /locus_tag="LP386_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBL1917456.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            76873..77772
                     /locus_tag="LP386_000185"
     CDS             76873..77772
                     /locus_tag="LP386_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HBL1917457.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            78289..79020
                     /locus_tag="LP386_000186"
     CDS             78289..79020
                     /locus_tag="LP386_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBL1917458.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            79165..81192
                     /locus_tag="LP386_000187"
     CDS             79165..81192
                     /locus_tag="LP386_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBL1917459.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGHSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRIDIPVENQRIGTFEGKLSWILADVPGN"
     gene            81300..82397
                     /locus_tag="LP386_000188"
     CDS             81300..82397
                     /locus_tag="LP386_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBL1917460.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            82704..>83151
                     /locus_tag="LP386_000189"
     CDS             82704..>83151
                     /locus_tag="LP386_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1917461.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRKL"
BASE COUNT        27254 a        14903 c        17660 g        23334 t
ORIGIN      
        1 caacagctcg tggtgataag aagagctata tttacgctaa cttcaatccg aagtatgctc
       61 aatttgcgat tacaattcta agaacttact acaacttttg tcgccctttt aaatcagcgg
      121 ataaaaaggt tttgacacct gctcaaagat tagggattac agataaacaa tttgattgga
      181 aagatataat ttatttcaaa tgacaaaaag agcttggagt aatcccaagc tcttgtgctt
      241 tatctttact gttcttcttc aattaacgca cccgttaact caataagttt tttctttcat
      301 atacatgaaa atagtagtta tacggatttt tatcattctt tatccctttt tgggcaaata
      361 cctcattcca ttcctcataa ttcacttctg gaaaaaaagt atctccttcg aattcatgat
      421 gtatttttgt gatgtacatt ttctcaacat aagggaaaaa caaattataa atctgttctc
      481 ctccgaaaat aaaaatttct tcttcgtttt tacataactc aaaaacatct tctattgaat
      541 gaacaatttc acaaccatta aaggtaaacc ccttatctct cgtcagaata atatttcttc
      601 tgtcaggtaa ggctcttccg attgattcaa ggttcttcct acctaatatt atcggatgtc
      661 cctttgtagt atttttaaca tattcccagt ccttgggaat cctccaagga atgtcattct
      721 ctttgccaat cactctattc ttatccatcg cagcaatcaa agaaactttc atttataaca
      781 cagccttttt aactaattta ccatctaatt tcttatttct atcaaaaaac cttttctcat
      841 tatcctgccc gttagttgaa taagcaattt tttctataag ttatattatc ataataccac
      901 aaaatcacaa attttcattc aattatcatt ttcaattgca ttttataaat cattttgtat
      961 gtaatttggt atgtaagtta aaatgaaaaa agtagtccat tttgaagtac attttgtcat
     1021 tttgtactcc aaaactgaac tacttacttg catatatacg cctttatagt ggagtactac
     1081 atttacgaga ttcggttaga gtatcagaaa aagaaaaaat aaaagttaca gaaatgtata
     1141 cttcaataaa tggtgaatta tgtaagattg atagagctta ttctggagaa attgttattt
     1201 tgcaaaatga gtttttgaag ttaaatagtg ttcttggaga tacaaaacta ttgccacaga
     1261 gaaaaaagat tgaaaatccg caccctctac tacaaacaac tgttgaaccg agtaaacctg
     1321 aacagagaga aatgttgctt gatgcccttt tggaaatctc agatagtgat ccgcttctac
     1381 gatattacgt ggattctacg acacatgaaa ttatactttc tttcttaggg aaagtacaaa
     1441 tggaagtgat tagtgcactg ttgcaagaaa agtatcatgt ggagatagaa ctaaaagagc
     1501 ctacagtcat ttatatggag agaccgttaa aaaatgcaga atataccatt cacatcgaag
     1561 tgccgccaaa tcctttctgg gcttccattg gtttatctgt atcaccgctt ccgttgggaa
     1621 gtggaatgca gtatgagagc tcggtttctc ttggatactt aaatcaatca tttcaaaatg
     1681 cagttatgga agggatacgc tatggttgcg aacaaggatt atatggttgg aatgtgacgg
     1741 attgtaaaat ctgttttaag tacggtttat actatagccc tgttagtact ccagcagatt
     1801 ttcggatgct tactcctatt gtactggagc aagcctttag aaaagctgga acagaattgt
     1861 tagagccata tcttagtttt aaagtttatg caccacagga atatctttca cgggcatata
     1921 acgatgctcc caaatattgt gcaaatatcg taaatactca actgaaaaat aatgaggtca
     1981 ttattattgg agaaattcct gctcgatgta ttcaagatta tcgcaatgat ttaacttttt
     2041 ttacaaatgg gcttagtgtt tgtttagcag agctaaaagg atatcaggtt accactggcg
     2101 aacctgtttg ccagacccgt cgtctaaata gtcggataga taaagtaaga tatatgttca
     2161 ataaaataac ttagtgcgtt ttatgttgtt atataaatat ggtttcttat taaataagat
     2221 gaaatattct ttaatataga tttgaattaa agtggaaagg aggagattgt tattataaac
     2281 tacaagtgga tattgtgtcc tatttgtgga aataaaacaa gactacgaat acgagtggat
     2341 actatactta aaaatttccc tttatactgc cccaaatgta agaacgaaac tttaattaat
     2401 gttcaaaaaa tgaatataat aacaatcaaa gagccagacg ccaagacgca gagccgataa
     2461 tttgagaaat gaaactctca tcttatcggc tctttttgtt tatctgaatt ttactgacta
     2521 gccttcaata tttcttgctt cattgatacc ttttgctagt gcttccatta aggatagttc
     2581 tttgtctgta aagctatcca tgtatttttc tacctgtaac cttcgagtgc ttttaatcaa
     2641 attatctgta ggtaagaaaa attcatcaat agatacatgg agtaatgata caagatcata
     2701 cagcacttgt gtacttgggt gttgtccttt gttttctata tttgttaaat aacgtgggtc
     2761 aatttcaatc attgttccca cttgttcacg agtgagaccc cgtttcattc gagcctcttt
     2821 aatcgctaaa ccaacggctc taaaatcgta tttatcttct tttttacgca tactaaatca
     2881 cctctataca ttttactgtt cctatataac cataaacagg tatagaaaaa catgttatat
     2941 agtttatgag ttcctataga acactgtgga atttattaat gcgatgaatc caatttcaaa
     3001 tagaaaggtc gctgatttta tttacctata caactttata aaatttagtc atactcctag
     3061 aaagtagata aaattggcga cttaatggag ggaaaagtcg ccatgagaaa gataatctgt
     3121 catctagttc tcttaattaa gttcttatca aaaaaactta tccacctgta ctggatagat
     3181 atgaccatca atgtggtttt gcagattaca tagatagaaa aatcaaagca tatgaacaga
     3241 gaaaacaatc tgtttatgtg cttttttggt cacttaataa atatctttta ggatttctct
     3301 tcatttatgc aacaaatccc ccgttcgtgt cggggtttag tatgaaggga gataaagaag
     3361 cacatgccac tccctttcac gacagaaagg gggtgaaaag catgaaacca tcttcttttc
     3421 aagaaaccat agaaaatcag tttgactata tctgcaaaca agttattgaa gatgaacgaa
     3481 aagattactt caaacatcta gacagactat cagcaaaaga agtctcgttt tctgatatag
     3541 ataactacct tgtcaactct ttttctactg ttgatacgta cgtcactgat ttccaactat
     3601 ttaaattatt tggattaaga atcaatgttg aaagtgattt attaagtgaa gccctgcgtc
     3661 atctttcaga gaaaaaacgg aacattattt tacttcatta ctttatggat atgagtgatg
     3721 tggagattgc ggagttacta aatttgaatc gttcgactgt ttatcgtcat cgaataagtg
     3781 gactagccat gattaaagaa ttcatgaagg agtgtaaaga atgaaaacag cttatccaag
     3841 ggttcccttc cccctcattg taaaggcgac agatggcgac gtggaagcaa ttaatcagat
     3901 tgttaaacat tatcgagggt atacctcaaa acgttcatta cgtcgcatga cagacgaata
     3961 tggaaattct catatggtta ttgatgaaac cctacgtggc agaatggaaa cgaaactcat
     4021 ctctaagatt ttatcgttcg aaattaaata gtcccatttt ttcgtggaag cgtgtcgaat
     4081 cgtatccacg cttcccgatt tgggaggttt gttattccat caaagcatat tgtgtgttca
     4141 gtaggttttg ataggctaac aagccaaacg ttctttgaca accaaataaa ggcaatcgaa
     4201 tacgtttcgg taagaaaaga gctgatgaac taacacgcca tgacctacaa aattagtgag
     4261 cgattcatgt tagtaattcg aaagtaatct ttagcaggat tgctgccatg actttcttat
     4321 cgtgataatg atactcccgt atagccatag tccgagcgtt agaagcgtca caggcaatgg
     4381 gtacggctac atgagaacca tgcagaagtg aaattcctgt gagctttgct agagctgttc
     4441 gattgctaag atattcttct cttgtcagtg tattattata aaactatttg atataattat
     4501 aggtgaatat tggagttttc ctagcctata attgggaaag gagtaataat gataacggtc
     4561 acaaaaaagg atttagttga gctaggatat ggaacttctt tttcagcaga catcataaaa
     4621 aaagcaaaag aattgatgat tacaaaaggg catatctact atcaatctcg aaagctagat
     4681 agagtccctc gtgaagctgt tgaagaaatt ctaggaattc ggttttcaaa tgaaaacagg
     4741 tctgagtagt ttttgcacag taaggagtaa aaactatggt taaagaccca ataaaaaaag
     4801 caaagaatgg aacctattat tttcgtgcaa atctaggtta tgattctaaa gggaaaaaaa
     4861 ttcaaaaata tcgtagtgga ttcactacta aaaaagaagc aagagaagaa tattcgaaac
     4921 tgctattgat gaaaccagaa gaattaagtg agaataagga taaaatgacg tttaaacatt
     4981 atatctttga aattttcctt ccatggtata agacacaggt aaagctcaga acatatgaaa
     5041 atcgcttacc aactattaag aagcatttct cttattttga taaaatggct gtttccgata
     5101 ttgagcctat tgatgtgcaa aattggcaac taaaattatc aaagaagtgt aagtcttctt
     5161 atgtaagagc tgttcaagga ctattttcag ttgctatgga tcgagcaatt gtccttggga
     5221 taaccaccac aaatccatct aagattattg gcaatgtgaa aaagcaaaag tctaaaattg
     5281 aattttggac aaaagaagaa tttgaaaaag taatctctct aatttacaaa gaagattact
     5341 atcaacactt tttatttatc tctctgtggt ttttatttat gactggaatg cgaattggtg
     5401 aagctactgc cattcaatgg gaagatattg attttgactc aggagtacta accatcaaca
     5461 aaacactcta ttacaagaat caatcgaatt atagatttgt tgaaccaaaa acaaaggcga
     5521 gcgttcgtca tattgtatta gataaatgca cattaactta tttatccgaa tggaaggaag
     5581 tacaacaaaa tctaattcag acagactttg taatgagcta taacggtatt cctacccaaa
     5641 aacatacact atcatatgct attgaacgct atgctaagct ggctggtatc catcgaatca
     5701 gaatccatgg gttacggcat tctcatgctt ccttgttaat cagtatggga gaaaatccac
     5761 ttatcattaa agatcgtcta ggacacgaag atattgagac gactttagga acgtatggac
     5821 atctttatcc taacagtaat ttcgaggtag ctaacaaatt aaatggagcc atttccttta
     5881 aagaagcaaa acaaaattat gatacttcac caaagaatca atttactgta gactacttgc
     5941 gaaacaaaga aatgaaaaaa gtgcaataaa agtgcagtaa aaagataaga agagccagaa
     6001 acccttggta taagaggatt tctagctctc ctacaactat tcccactcca ctgttgctgg
     6061 tggtttagaa gtgatgtcat acacgatacg gttgacgtgg gctacttcgt ttacgatacg
     6121 tacagagatt ttttgcaaga cttcccatgg gatacgggca aagtcagcgg tcattccgtc
     6181 gattgaagtt acagcacgga taccgactgt gtagtcgtaa gtacgtccgt cacccataac
     6241 accgacagag cggatccctg gaagaacagt gaaatattgc cagatatcac ggtcaagtcc
     6301 agcagctgcg atttcttcac gcaagatagc atcagattcg cgtacgattt ctagcttgtc
     6361 ttcagtgatt tcgccaagaa cacgaatacc aagaccagga ccagggaatg gctgacgcca
     6421 aacgattgaa tcaggcatgc ctaactgagt ccctaattca cggacttcgt ctttgaataa
     6481 tgtgtttaat ggttcgatca attcaaattg catatcttct ggcagtccac ctacattatg
     6541 gtgagatttg atcgtctgtg ctgtttctgt accagattcg ataacgtcag tatacaacgt
     6601 tccttgtgct aggaaagaga cgccttcttc accagcaagt tttgttgctt cgtcatcaaa
     6661 aacatatacg aattcattcc caatgatttt acgtttttgt tctgggtcag atacaccttt
     6721 caacttgtct aagaagcgat ctcttgcatc gactttgatg atgttcaagc cgaattttcc
     6781 gcctagactt tccattactt gttccgcttc gcctttgcgt agcagaccgt ggtcaacaaa
     6841 gatagatgtc aattggtcac cgatcgcttt ttgtaaaaga accccaacga cactagaatc
     6901 aacgccacct gaaagaccaa gcaagacttt tttgtcacca acttgttcac ggattttttc
     6961 tacttgcata tcgataaagt tatccattgt ccagttacct tcacagtgac aaacatcaaa
     7021 ggcaaagtgg cgcagcaatt cgattccgta ttcggaatga cgtacttctg catggaattg
     7081 gataccataa aaattacgtg ttgtgtcttg gatagaagca atcggacaat ctttgcttgt
     7141 tccgactgtt tcaaagcctt caggaacttt agttaccaag tcaccatggc tcatccatac
     7201 tgtttgttgt tttggtgttt ctttaaacaa gacagcttga tcgcttgtta cttctaacaa
     7261 ggctttccca tattcgcggt ttttagcagg ctctacggaa ccgccaagtt tgtacgtgat
     7321 caattgcata ccatagcaaa tccctaatac aggaatacct aaattgaaga tctcaggatc
     7381 gatcccaaat gcattctcat catatacact gtttggtccg ccagaaagaa tgattccctt
     7441 tggattcatc gcttttactt cttctgcagt aatgcggtgg ctcaataatt cggaaaagac
     7501 tccaagatca cgaatacgtc ttgtgatcaa ttggttatac tgactaccgt agtctaatac
     7561 gataatcttt tcaacgttcg tcatatcggc aacgtttgtc aaatttatta cccctatccc
     7621 tttaaatttt atctcaaaat agtcaaacta ttttaaaatg ctaatatttt cgcatgaaaa
     7681 tcgaatcgat gatatgattt tcagttttat ggagaattat atcggctctt cctcgtgtag
     7741 gcaagatata ttcctgtaaa tttttcaaat tcacattttt ccatacatct tttgccattt
     7801 taaaggcttc ttcacgatct ccgatagcaa aacgataata ataattctct ggattttgga
     7861 aagccgtatc cagtaacgca ccaaaacgat ccaaatacca tttttcgatc agcacgggat
     7921 cggcatcgac atagacagaa aaatcaaaaa agtcgctgac gtagatttgc tgattcgcag
     7981 gtaattgaag cgtattgatc ccctcaacga tcaagatatc aggctgctgg atcaattcgt
     8041 acttgtctgg aatgatatca tacacatcat gtgagtaaac aggtactttt atctcttcct
     8101 gaccagattt tacacggttc aagaaatcga tcagcatctc catatcataa ctttcaggaa
     8161 atcctttacg gtccatgatt ccacgctctt ttaatatacg atttggataa agaaatccgt
     8221 cagtcgtgat cagctgaacg tttcttcgtt tgaaggtacg agacaaaatc gtctgcagca
     8281 gtctggctgt tgtacttttt ccaacggcta cacttccggc gatcccgata ataaaaggcg
     8341 gtacttctac gtatttatga agaaataaac ctttactcaa gaacaaagat tcaaattctt
     8401 tcatataaag ataaatcaga tgagcaagag gtacatagat atctcgaaca tcctgcatgg
     8461 aaatgcggtc attcaaactt ttgatattat ctagttcatc ttgtgtcaaa ggtgcttgcc
     8521 cattacgata aaattctcgc cattcttctc ttgccacacg gtagtagttc attggatcat
     8581 tcatattagc ctcctgcgtt ctcccatcaa tggaactatt ttaacacaaa ataaacgcaa
     8641 accccaccac ttaagagaga ttgccgatct ttttgtataa tctttataat agaaagaaac
     8701 ggagtcttat tcttgacttg cgcacggata cataaaagga tagactgttg tcatgaaaga
     8761 aatgagaagg atggaagaca tgacaaatca ttactattct gaacgcccag atacggcgca
     8821 cgattttgaa caatgggctt ttgagttaaa aggcagaacc tttcaatttg taacagattc
     8881 tggtgtattt tcacgtgaaa cagtggatta tggttcacgt gtcctgattg atgctttcga
     8941 ttgggaagag ttacctgatg aaggaaagat cttagatgtg ggatgcgggt atggaccgat
     9001 tgggttagct ttggcatttg cgacacagcg gtttgttgaa atggtcgaca ttaatgaacg
     9061 agcggtaagt ctagcgcaag gaaacgcaaa gcgtaaccaa atcgaacatg ttgatatcca
     9121 tcaatcgaat atctatgaag cagttcatga agaaacctat gcagctatcg taagcaatcc
     9181 gccgatccgt gctggaaaaa aagttgtaca tgaaattttg acaggcgcat atcctcggtt
     9241 gaagaagggc ggtacactga caattgtgat ccagaagaaa caaggagcgc cgagtgcgca
     9301 aaagaaaatg gaagaaacat ttggtaatgc agaaatcgtc acaaaagata aaggatatta
     9361 tatcatcaaa agtgtgaaag aataactagc tgaaaaatag tggagcgacg aaagagtgga
     9421 actgggcgtg catgtacggg tacgtatcag ttcttttttt gttgagaagt ttttaaaaac
     9481 aaagaactat tttttcttca aaaagaaata gtaggaacag agtcgttgtt ttttacgata
     9541 aaataaataa gatacagaac ttgtatagaa ggctgccaag tcggtagata aaggaggttt
     9601 ttatcaaaaa acatactttc cttttttctc tattcttttc ttgggggttt tggtacactg
     9661 atagggaatt tagatagaag ggagccaata ggatgaagct gaccatcaga gatatcgcag
     9721 aaatggcagg cgtatcagta acaactgtct cacagatttt gaataacaaa ggaagcagat
     9781 ttagtgataa gacaagaaaa aaagtgttgt cgatcgtgaa tgaacatcat tataagcccg
     9841 attatttcgc ttcaaatgtg atcaatcgac attcaaagac catcggaatg atcgtccctg
     9901 atgtcactga tttcttcttc tccaaactga tcgaaggtgt agagagctat ttgaatcctt
     9961 tgggctatgt gatcatgtta tgcaattctc gtcatagcca agaaaatgag atcaagtatt
    10021 tacaagagct ttcccaccgc tcagtggacg gaatcttgct ggccacacca aatattttac
    10081 ctgagaaata tgcattagac agcggttttt atcaaaaaat gccaatcatt ttaatcgatc
    10141 gcggattgaa tcgtcgggat aacggacggc ttatcgtaaa ggaatatgag ggcgcctatc
    10201 aagctgtttc gctgtttatt gaaaatggcc atacgaagat cggcatgctg aaggaaacca
    10261 ctggatacta tcaattagaa gaacgtttca acggatatcg tcatgcgctg aaagatcatg
    10321 gcctgccttt taatgggaaa tttgttgaac atggagagtt gactgtccaa ggtggatata
    10381 ctgcatcaaa aaaattactc aaacataaag atatcacggc tattttttgc gggaatgatg
    10441 ccatggcgat cggatgctat caggcgatcg atgaattggg caaaaaaatc ccagaagata
    10501 tctcagtcat aggattcgat ggattaaagc tgtcagaata catgattccg caattgacga
    10561 cagtgcagca gccaagtttt gatattggat tttatgctgc acgtttcctg atcgatacga
    10621 tcgaatttcc tcaaagaaaa gttccgaaca aagtgttcga aacaaaatta attattcgtg
    10681 agagcgtaaa agtattgaca aagggctaac tcggcggtat attgcttatg taagcattta
    10741 caaaggctag ttagtgcttt ttttattttt agtaaaccag tttactaaag tggtttacct
    10801 ttcctaaaaa taatgtataa taccgaatga agacaaggag gatcaggcaa tgcgaatggt
    10861 ggatctgatt gaaaaaaaga gggatggaaa cgagctgtcg aaagaggaaa tcgagtacat
    10921 cgtcacgaac tatacgaatg gaaagattcc agattatcaa gtcagtgcat tattgatggc
    10981 aattttttat caagacatga caaatgaaga aatcacgaac ttaacattgg cgattgctaa
    11041 ttctggtgat gtcatcgatt tgagttctct tgaaggaata aaggtagata agcattcgac
    11101 aggtggcgtt ggtgacacga ccacattgat tttagccccc ctagtagcta gtgtcggagt
    11161 gacagtggct aaaatgtctg gacgcggtct aggttacaca ggtggtacac tagacaagct
    11221 agaagcaatt cccggatttc agatcgagct ttcggatgaa gaatttgtac gcattgttaa
    11281 tgaaagtaaa gtagcggtaa ttggtcaatc aggaaacttg gcaccggcgg acaaaaaatt
    11341 gtatgccttg cgtgacgtca cagcgaccgt tgattctctt ccgctgattg ccagttcgat
    11401 tatgagtaaa aaaatcgcgg caggagcaga tgcaatcgtt ttggatgtga ccactggaga
    11461 cggtgctttc atgaagaaca tcgaagatgc aagacgtctg gcaaagacca tgacgagcat
    11521 tgggaaactg gctaaccgag aaacagtggc ggttatctca gatatgtcag aacctcttgg
    11581 cgaagctatc ggaaatagtc tagaagttgt cgaggcaatc gaaacattac aaggaaatgg
    11641 tccagaagat ctagtagaaa tgtgctacgc cttaggaagc caaatggttg ttcttgctgg
    11701 caaagctaag acaaccgatg aagcaagaac gttgcttcaa gaagctctgg aatcaggtaa
    11761 agcgttagca aaattcaaag aaatgatcca aaatcaaggg ggagacccag cgatcgtgga
    11821 acatccagaa cgaattttga ctgcacgcta cacaatggag cttcctgcta aacaaagcgg
    11881 agttgtgtca aaaatcgtgg caaatgaatt aggaattgct gcaatgatgc taggtgctgg
    11941 gcgtaaaacc aaagaagaag atattgatca cgctgttgga ttgaaactgc ataaaaaaat
    12001 tggtgacact gtgacaaaag gtgagtcact attgacgatc tatagtaacg acgaagaaat
    12061 cacttctgtc attgaattat tatataaaaa tattgaaatt ggtgaatcgg caatgaagcc
    12121 aacgttgatt catgacatca tcacagaata aaggaaaaaa gcggacttta ccgttttaaa
    12181 gaaaagggga aaagaaatgg aactaaaccg aatgatcgac catactattt tgaaagcaga
    12241 cgcatctaaa gaagctgtga tgcaaattat cgaagaagca aaaaaatacc atttttattc
    12301 tgtctgcatc aatccagcat gggttgcgct agcgaaagaa caattacaag gtgagccagt
    12361 agccgtatgt acagtaatcg ggtttcctct aggagcaaac acacccgaga caaaagcatt
    12421 tgaaacaaca gatgccatca ataacggtgc agatgaagtc gatatggtca tcaatatcgg
    12481 tgctttgaaa tcaaaggatg atcaacaagt ccaaaaagat atcgaagcag ttgttgaagc
    12541 agcaaaagat cgtgcgcttg tcaaagttat tattgaaaca tcgttattag atagagaaga
    12601 aatcatccga gcttgcgaaa tagcaaaagc tgcaggcgct gattttgtca aaacatcaac
    12661 tggtttctca acaggcggag caaaggtaga ggatgtccgt ttgatgcgtg aaactgtagg
    12721 accagaaatg ggtgtcaaag cttccggcgg tatccataac gaagaagaag caatggcaat
    12781 gatcgaagct ggtgctacaa gaatcggaac aagcgcagga gtagcaatcg tatctggttc
    12841 aactggtgaa ggctattaat tttttcaaag gagaagctca tggcagaact caaacaagaa
    12901 tggatcaaca cagctattga agcgttagat aaagcctatg ttccttattc ccattttccg
    12961 gtaggcgctt gtctcgtaac ggaatcaggc aagatttatc aaggcatcaa cattgagaat
    13021 gcatcatttg gattaacgaa ttgtgccgag cgcacagctt ttttcaaagc agtatctgaa
    13081 ggagaaaaaa catttacgca tctagtcgta gcggggcaca cccccgatcc tatctctcct
    13141 tgtggtgcat gtcgacaagt aatggcagaa ttctgttccc ctgatatgcc ggttacgcta
    13201 gtaggagaca atggtgtgac gaaggcaacg accgttcgtg cactgctgcc ttatgcattt
    13261 actgaaaaag atctataact catgttcatt cagtcagctg actgttgaaa aataaaacaa
    13321 ttattttagg aggctttaca gaaatgaaaa aagcaaaatt atttggttta ggtgctgtcg
    13381 cactagcagc agggttattt ttaggtgcat gcggcaacaa cggctctact gattcatccg
    13441 gtggcaaaag ctcatcagac acaacaactg cagcattgat cacagacaca ggtggtgtag
    13501 acgaccgttc attcaaccag tcagcttggg aaggactaga aaaatggggg aaagatcaag
    13561 gactttcacg aggaaatgat ggcttccaat atttccaatc ttcaaatgaa tcagattaca
    13621 tcccaaatat tgaccaagca ttgaatgctg gattcaaaac gatttttggt attggttata
    13681 aactaaaacc agcgatccaa gaacaagcaa caaacaatac aggtacgaac tttgttatta
    13741 tcgatgatgt catcgatgga ttagataacg ttgtatctgc aactttcaaa gacaacgaag
    13801 cttcttatct tgcaggtgtt gcagcagctt atacgactga aacaaacgta gtcggcttta
    13861 tcggcggtgt aaaaggtgaa gtaatcgatc gttttgatgc tggattcaaa gccggtgttg
    13921 atgcaggtgc gaaagaatta ggaaaagaaa tcaaagtatt gaatcaatat gctggtgact
    13981 tctctgctcc agataaagga cgttcaattg ctcaaggtat gtatgcacaa aacgcagata
    14041 tcatcttcca tgcttcaggc ggtacaggta acggtgtatt ccaagaagca aaatcattga
    14101 acgaatcagg cgacaaaaaa gtttgggtta tcggtgttga ccgcgaccaa tcagacgaag
    14161 gcgaatacac attaaacggc gaaaagaaaa acttcacatt gacatctaca ctgaaagcag
    14221 ttggaacagt agtagaagat ttggcacaaa aatcagcgga cggtaaattc cctggcggcg
    14281 aacacactgt ttatggattg aaagaagacg gtgttggtct aacagaagga caactttctg
    14341 acgaagcgaa aaaagcagtt gatgaagcaa aagaaaaaat catttcaggt gacgtaaaag
    14401 ttccagaaac tcctgaagaa aactaaaacc atttctatag ccttgttaga cacatgtttg
    14461 acaaggctat ggtttgatta gaacaagaat tgttcattta tccaagctgc cttgtgacag
    14521 tttggataag ggaacaactc cctgaagtaa tgtttgtttc aaaagaagaa cgctcactaa
    14581 gcgtgaatct tagtcaatcg ttgccctaga tagaaatcgt taggatgtga aaaaaaggtg
    14641 gttcaagaaa atattgtcat agaaatgcag aatattacca aagaatttgg aacattcaag
    14701 gcaaatgaca acatcaattt acaagtaaag gcaggagaaa ttcatgcgtt gcttggagaa
    14761 aacggtgctg gcaaatctac attgatgaac gtgctttccg gattattaga gccgacatca
    14821 gggaaaattt tgatgcgtgg gaaagaagta aagatcacaa gtccgaccaa agccaaccaa
    14881 ttagggattg ggatggtcca tcagcacttt atgcttgttg atgcctttac tgtaacagaa
    14941 aacatcgtgt tgggaagcga gcctagtcgc gcagggatgc ttgaccataa aaaagcacga
    15001 aaagagatcc aaaaagtttc tgaacagtat ggattgtcag tcaacccaga tgcttacgtt
    15061 cgtgatattt cagttggaat ggaacaacgg gtagaaattt taaaaacact ttaccgagga
    15121 gcagatgtac tgatttttga tgagccgaca gctgtattga cccctcaaga aattgatgaa
    15181 ttaatcgtga tcatgaagga attagtcaaa gaaggcaagt cgatcatttt gattacgcat
    15241 aagttagatg aaatcaaagc agtagctgac cgctgtacag ttatccgccg tggaaaagga
    15301 atcggtacag tcaacgttaa agacgtaacc tcacaacaat tagccgatat gatggttgga
    15361 agaacggttt cattcaaaac gatgaaaaaa gaagcgaagc ctcaagaagt cgttttgtct
    15421 attgaaaatc tagtggtgaa agaaaatcgt ggattagaag ccgtgaaaaa cttgaactta
    15481 gaggttcgtg ctggcgaagt acttggtatc gctggaatcg atggaaacgg gcagtcggag
    15541 ttgatccaag ctttgactgg tttgcgaaag gcagaaagcg gacatatcaa gctaaaaggg
    15601 gaagacatca ctaataaaaa accccgaaaa atcactgaac atggtgtagg acacgtgcca
    15661 gaagaccgtc ataaatacgg gttagtccta gatatgacat tatctgaaaa tatcgcacta
    15721 caaacctatc atcaaaaacc ttacagtaaa aacggcatgc tgaattattc agtaatgaat
    15781 gaacatgcca gagaattgat cgaagaatat gatgttcgaa caacgaatga acttgttccc
    15841 gcaaaagctt tatcaggcgg aaatcagcaa aaagcaatta tcgctcgtga agtcgaccga
    15901 gatcctgatc tgttgattgt tgcaaatcca actcgtggac tggatgtagg tgcgatcgaa
    15961 tttattcata aacgtctgat cgaacaaagg gacaaataca aagcagtgtt actgatcagt
    16021 ttcgaattag aagaaatttt aaatgtttcg gatcgtattg ctgttatcca tgaaggagaa
    16081 attgtcggta tcgttgatcc gaaagaaaca tctgaaaatg aattaggtct attgatggcg
    16141 ggctatacct tagaagaagc acgaaaagag ttagaaaagg gggctggcgc acatgaatga
    16201 tcgcagcgaa aaattccgta atttattagt gcctgtactt tcagttgttt taggattgat
    16261 cttaggcgcg atattgatgg ctgcttttgg ttttcagccc atccaaggtt attcttctat
    16321 gctagatgca gcccttggtt cgcaaagagg gataggtgaa acgttaaggc aagcaacgcc
    16381 gttgattttt acagcattag gtttttctgt agctaactca gctgggtttt tcaatattgg
    16441 gctttctgga caagcacttt gcgggtggat cgtcagtgtc tgggtggcac ttgcgtttcc
    16501 agatctgcca aaagttgttt tgcttccgtt atgcgtgatc ttaggtgcct tagctggtgc
    16561 gatggcagcg gctgttccag gtttacttcg agcatttttt ggaacaagtg aagtgatcgt
    16621 aacaatcatg atgaactata tcttattata cgtaagcaca tttgctttac atgaagtgat
    16681 gcctgaaagc tatcgctcaa gtttggactc ttccaatatg atcagtcaaa atgcctcact
    16741 gcggttacca tggttaacac aagcttttgg cggctctcgc gtaaactcag gattattttt
    16801 agcaatcatc gcgcttattt tcgtttggct gctgatgaag aaaacgactt taggatttga
    16861 aatccgttct gttggattga atccttttgc ttctgagtat gcaggaatga gtagtaaacg
    16921 tacgatcgtt ttgtcgatgg tcatttctgg cgctttggca gggcttggcg gtgtggttga
    16981 aggattagga acgtatcaaa acttctttgt tcaaacgact tcgctatcta ttggatttga
    17041 cggaatggct gtttccttgc ttggttctgg atcagcaatc ggtattcttt tatcagcgat
    17101 cttgttcagt attttgaaga tcggtggact tggcatgcag acaggagcag gtgttccgtt
    17161 tgagatcgtc aatgtatcga ttgctttgat tatcttcttt gtcgggatca acttcctgat
    17221 tcgtttcgtc atggctaaag tcttccaagg gaaaaaacaa gaagagatcg ttgcgacaat
    17281 agaatcgaaa ccaacgaatc aaaaccatga agggggcgaa ctataatgtc gactatcgaa
    17341 ttaattgcct tgatccttac ttctacactg gtttattcaa caccgctaat tctaacgtca
    17401 ctaggcggaa ctttttctga acgaagcggg atcgtaaacg tagggctaga gggaatcatg
    17461 gtcatgggtg cttttagttc catcgttttc aacttgacga tgagtccatc acttggttct
    17521 atgacaccat ggatcgctat tttagtgggt ggcgtcgtag gtatcctatt ttctctgatt
    17581 cacgcagtag caacagtcag tttgcgtgct gaccatatta tcagcgggac agtaattaat
    17641 ctgatggcac ctgctttagg tgttttcttg atcaaagcat ggtatggtaa aggtcaaact
    17701 gataacatca cgcagaatct ggggtatttt tctttcccag gattagcaga tattccggtc
    17761 attggaccaa ttttctttaa aaatacattc ttacctgctt attgtgctat tttgattgct
    17821 gtcctagctt gggtgatcat cttcaagacg aaattcggct tgcgcctccg ttcagttggt
    17881 gaaaatcctc aagctgccga cacattaggt atcaatgtat atgctatgcg ttattcaggc
    17941 gtactgattt ctggcttgtt aggcggtatg ggcggtgctg tttttgctca gtcgatttcc
    18001 ggtaactttt cagctggtac gatcgttgga caagggttca tctccatggc tgctatgatc
    18061 tttggtaagt ggaatccttt aggggcaatg ggtgcctcat tgttctttgg ttttgctcaa
    18121 agcttgagta tcattggcgc acaattacca gttatttctt cgattccgcc agtattgctg
    18181 caaattgctc catatttgct gacaatcatt gtgctggttg ttttcttagg gaaagcttct
    18241 ggtccaaaag caaacgggaa gaactatatc aaatcaaaat aatcttttag cgaataaaaa
    18301 gggtgggtta cgggaagtgt ttttcgtctc gccctttttg ttttaaaggc aataaaaata
    18361 aaaagaaaga aggaataatc atgtttaaac gcgtacatct gatcgtcatg gattcagtag
    18421 gaattggaga agcaccagat gccgataagt tcggtgatgt tggttctgat acattaggac
    18481 acattgcgaa agaagcagga ttgaacgttc cacatttaga gcagcttggt ttaggaacga
    18541 tccgtcctct tgaaggtgtg gaatcagtga aagatcatca aggctatgcg acgaaattag
    18601 aagaagtttc tgtagggaaa gatacgatga caggccactg ggaaatcatg ggattgaata
    18661 tcaaaactcc atttcgtgtg tttcctaatg gattccctga tgatctgatc aaacaaatcg
    18721 aagaattttc tggccgtaaa gtcgtatgta acaaacctta tagcggaaca gctgttattg
    18781 acgattacgg tgaacaccaa atgaaaacag gcgatttaat tgtatatact tctgccgatc
    18841 ctgtccttca gatcgcggca catgaagaaa tcattccttt agaagaatta tatcggattt
    18901 gccaattcgt tcgtgatata acaaaagatg atccgtatat gattggccga atcattgcac
    18961 gtccgtacgt gggtgaacca ggagacttca cacgaacaag caatcgccat gattatgcgt
    19021 tgaatccatt cggacacaca gtccttgatt ctttgaaaga agcaggaaag gacgtgattg
    19081 ctgttggaaa gatcaacgat attttcaacg gacaaggaat cactgaatct gtccgcacga
    19141 aaagcaatat ggatggcgtt gaccagctgc tgaaagttat gaaaaacgat ttttcaggaa
    19201 tcagctttac caatttagta gattttgatg cattatacgg tcatcgtcgg gatgtagtcg
    19261 gctatgcgca tgcgattgaa gaatttgact tacgaattcc agaattgctt gaagcgatgg
    19321 aagaagacga cttgctaatg attacagccg atcacggaaa cgatccgacg tttactggta
    19381 ccgatcatac gcgagaatat gtaccgttat tggtttacag taaaaaaatg aaagaacaag
    19441 gggcattgcc tcaaggatat tattcagata tttcagcaac gattgctgag aactttagtg
    19501 tttcttcgac tgaaaatggc gaaagcttct tgaaattatt aaaataatct ttttaaatag
    19561 gagaaagcaa atgaccaagt taagcgagat gttacaagaa acgacccagt ttatccttga
    19621 taaaggagta aaagaaattg attttggttt gattctaggt tcaggattag gtgaattagc
    19681 agatgaaatc gaagatgctg taatgatttc ttatgatgag atcccgttct ttcctgtttc
    19741 gacagtagtt gggcatgcag gaaagctagt ttatgggtct ctggcaggca agaaagtgtt
    19801 agccatgcaa gggagattcc actactatga aggtcattcc atgcaaacag tgacctatcc
    19861 agtacgtgtg atggccggac taggggccca ttcagtcatt gtgactaatg catgtggtgg
    19921 tgtcaacgaa tcatttgtac caggagattt gatgctgatt accgatcata tcaattttac
    19981 tggtgaaaat cctttgatcg gtccgaatga agatgcaatg ggccctagat ttccagatat
    20041 gagtcaagct tatacgcctg actatcaagc aacagcaaaa gcagcagcag aaaaactagg
    20101 tttggatctt aaagaaggcg tatatatggg ctattctgga ccaacttatg aaacgcctgc
    20161 ggagatccga atgtctcgga caataggagc cgatgcagta gggatgtcga ctgttccaga
    20221 agtcatcgta gcagctcaca gcggattaaa agtgttagga atctcttgta ttaccaactt
    20281 agcagcaggt atgcaagcga atctgagcca tgaagaagtt gtagaaacaa ctcagagagt
    20341 caaacaatct tttaaagcat tggttaaaga aacattgaca ttattgtaat aggaggaaca
    20401 ataaaatgag tgtgcatatt gaagcgaaag aaggcgagat cgccgataag attttacttc
    20461 cgggagatcc tttgcgagct aaatatattg cggagacttt tttggaagat ccagtttgtt
    20521 acaatcaggt acgcggtatg ttaggcttta ccggcaaata taaaggagaa cgtatttctg
    20581 ttcaaggaac aggaatggga atgccatcag ccaccatcta tgcccatgaa ttgatccagt
    20641 cgtatggtgt aaagaaattg attcgagtag gtacatgcgg tgcattgtca aaagacgtcc
    20701 atgttcgtga tttagtacta gcacaaggtg cagcgaccag ttcttcgatg atcgaaaaaa
    20761 atttccaagc ctttcatttt cctccaatca gtgatttcaa tctattactg aaagcatatg
    20821 agatagctaa agaaaagggc tatacggttc atgtaggaaa tgttctttcg gaagattctt
    20881 tctacaaaga tgatttgaca gagacgttcc aattagctga acttggcgtt ttaggagtgg
    20941 aaatggaagc agcggctctt tattacttag gcgcgaaata ccatgtgcag acattaagtt
    21001 tgatgaccgt tagcgaccat ttgatcaccg gtgaagaaac aacagctgca gaacgtcaat
    21061 ctacgttcaa tgaaatgatc gaagtaggat tggaaacagc gatagcagaa taagaaggaa
    21121 atgaaaaagc tgccctgcat taagtaataa gaacatccaa gcaaaaatag ctcctcatgt
    21181 ttttgacttg gctggactta ttattgcaaa tgtaagcttt tgaacaccgt ttaccaagag
    21241 gttgtgaatc tgccgtttaa ctctgagtca caaggaacaa tttcaaaaaa cagcttttca
    21301 tgtttgatga atattgtgac ttgtgaccga gaagttggca ggagaaaacc gtttatacga
    21361 aaaaagggac tgtgacaaat cgtgtcacag tccctttttt atagtgtttt ttataggtag
    21421 tattttttag caactgttaa gtcatcattt aattcataaa caagtggttg acctgttgga
    21481 atttcaagat ccatgatgtc ttcgtcagag ataccttcga tatgtttagc tagggcgcgt
    21541 aatgagttac catgtgcagc tactaaaaca gttttgttgt ctagtaatgc tggagcaatt
    21601 tcatcttgcc agaatggcaa agcgcgttct aatgtcactt tcaagttttc tccaccagga
    21661 atatcgcgtt tgtctaacat tgcgtaacga cggtcatttg ctgcagaacc ttcgtcagtt
    21721 tcttccatta atggaggaag agtatcgtaa gaacgacgcc agatgtgcac ttgttcgtcg
    21781 ccgtattttt cagctgtttc ttttttgttc aaaccttgta atttaccata gtgacgttcg
    21841 tttaagcgcc atgatttgat ttgtggtacc caaagttgat ctgaatattc taagatcaag
    21901 ttacatgttt tgattgcacg agttaaaaca gaagtgtaag caacatcaaa ttcgattcca
    21961 gcttctttga ttttgcgtcc gccttctttt gcttcttcga ttccttctgg tgctagattt
    22021 acatcagccc aaccagtaaa ttggttcaat gcattccatt cactaagacc gtgacgagaa
    22081 aaaactaatt ttggcatgtt tagctctcct tttaagatag gtttatattt ctgaaatttt
    22141 cagttctgtt ttattgtaca attttttgga agagatttcc atcgaaaaat tagataagat
    22201 tctatgagaa aacaagtaga gaatataaaa aaacgaacag tgcccacgca actgttcgtt
    22261 tttaggtatt agatgcataa ttgctcgatt tctttttcag gtaaattgat atatttataa
    22321 catgttccaa ctgaaacacc gcattttgaa gaaataaatt ggatcgtttc ttttttttca
    22381 taatagagac gtcggatttt tttgatcgtt tttgcatcga tttttggtct tccgccgatt
    22441 tttccttttt tacgagcttc atctaatcca actaatgtac gttctttgat caatgcgcac
    22501 tccatgtttg ctaggttttc cattaattgg aaatagattt ttcccatttc gcgcgtatcg
    22561 attccttcat caagactaat caagtgcagc ccgcgatctt tgaataattg cgtgagttct
    22621 gttaattgcc gcgtagattt gcctaatcga tgaagttggc aaatgactag tgcatcgcct
    22681 tgttgcatgt cagcgatcac tgactccaaa tgaacagcag tagaatcatt ttgttccact
    22741 tcatatgtct catggaaaat ttcttgacaa ccaaagtcag ataattgatc aacctgagtt
    22801 gttaaatcaa cgtcatttat ggttgtgcgt gcataaccaa taattttcat ggtgattcct
    22861 ttctagcagt gattttctaa ctggatataa cagtaaaaat gtagcataaa gtacgtcaaa
    22921 aagatagttt tttcgcaaat tttccgctgt ctttttttat tggatgatca agcagttttt
    22981 ctttatttac gacggattgc gtcaagaatc tcaacgcctt tttctgagcc gacaactact
    23041 ttagaaacca tgtttaggaa aagcccatgt tctactaccc caacaagttc atctaaatag
    23101 gtagctaagc tttctggctg ttcgatgact tctagatgca gatcaatgat gtaatgacca
    23161 ccatctgtgg ttaagacttc tccgttttcg tctgtacgca agacgggttg gaatcttttt
    23221 tcttcaaaaa tatgaagtag ctgttgggag ccataaggga tcacttcaac tgggagtggg
    23281 aacttcccaa gtttatcgac taatttagaa gaatcaacga tccaaatcgt ttcttttgag
    23341 tacgtagcga ctattttctc gaaaagcaaa gcagcgccgc cgcctttgat cccttgaaaa
    23401 tcagcactga tttcatcagc accgtctatt gtcaaatcga ctacggggac ttcatcaata
    23461 ctctttaacg gtattcctaa tttttccgct tgttcttttg tcgcatttga agtagtaact
    23521 cctgtgatac gtaaaccttc ttcacgcata cggcgaccaa tctcttctac catataatag
    23581 gcggttgaac cggtcccgag acctacgatc atcccgtcct ttacgaattt cgcggcttca
    23641 atgccagcta attgttttaa attcatcttt gcgtccacct ttttttagtt tgagcatcgt
    23701 gctttcctca ctattttagc gtgatttacg gtaaaaagat accattcttt tttattccaa
    23761 taaagctttt tcaaaaaaaa ttgcatctct tgttgacatg ttttttcatt cgtgatattc
    23821 taacaaaggt gctttatcta caggtttctg tgaagaaacg tgctgactgt ttatcaaagc
    23881 atatttgata aggatgcaga cattgcattt attttttatc acaaaaaaag aaccacctgg
    23941 atgtgtggaa ctagacgcaa atcgtgggaa ggaggaaaca aggaatgcct acaattaacc
    24001 aattagtacg taaacctcgt aaatcaaagg tggaaaaatc taattcacct gctttgaaca
    24061 aaggatataa cagctttaag aaaactcaaa ctaacgtaaa ctcacctcaa aaacgtgggg
    24121 tagcaactcg tgtgggtaca atgacaccta aaaaaccgaa ctcagcttta cgtaaatatg
    24181 cacgtgttcg tttgtcaaac ttaattgaag ttactgctta tatcccaggg attggtcata
    24241 acttacaaga acacagtgtt gtattattac gcggtggtcg tgtaaaagac ttaccagggg
    24301 tacgttacca tatcgttcgc ggtgctttag atactgctgg tgttaacgac cgtaaacaaa
    24361 gccgttctaa atacggaact aaaaaaccta aagcttaatt ttaattatta aacaaatgaa
    24421 acttgcttct actatataga agtaattact atgaacaata tttcggaagg aggagttacg
    24481 gatgccacgt aaaggtcctg ttgcaaaacg tgatgtttta ccagatccta tttataactc
    24541 aaaattagta actcgcttga tcaaccgtgt aatggttgac ggaaaacgcg ggattgcagc
    24601 taacattatc tataatgcct ttgacttgat caaagaatct acaggtaacg atccattaga
    24661 agtgtttgaa caagcaatga aaaacgttca acctgttctt gaagttaaag cacgtcgtgt
    24721 tgggggttca aactaccaag taccagttga agttcgccct gaacgccgcg ttactctagg
    24781 tcttcgttgg gtagtaaact acgctcgctt gcgcggtgaa cacacaatgg aagaacgctt
    24841 agcaaaagaa atcatggatg ctgcaaacaa cacaggtgct tctgttaaaa aacgtgaaga
    24901 cactcataaa atggctgatg ccaaccgtgc gtttgctcac tatcgctggt aagattctct
    24961 ctgtttggtc ggcttttata agtcgacctc agatagtgtc cttattttta gcaactagat
    25021 agtaaagaga ggagaaacaa ggagaatgac cagagaattt tctttacaaa acactcgtaa
    25081 tatcggtatc atggcccaca tcgatgctgg taaaacgact gctactgaac gtatcttgta
    25141 ctatactggt aaaatccata aaattggtga aactcatgaa ggagcttcac aaatggactg
    25201 gatggaacaa gaacaagaac gtggtattac gatcacttct gctgctacta cagcacaatg
    25261 gaagggtcac cgaatcaaca tcatcgacac accaggacac gtagacttca cagttgaagt
    25321 tgaacgttca ttgcgtgtac ttgatggtgc tgtaactgtt cttgatgcac aatcaggtgt
    25381 tgaacctcaa actgaaacag tttggcgtca agcaacaact tatggtgtac ctcgtatcgt
    25441 atttgcaaac aaaatggaca agatcggtgc tgacttctta tattcagtat caactttaca
    25501 tgaccgtttg caagcaaacg ctcacccaat ccaattacca attggtgcgg aagacgactt
    25561 cacaggaatt atcgaccttg taacaatgaa ggctgaaatg tatacaaacg atcttggaac
    25621 agagatcgaa gaaacagaaa ttcctgaaga ataccgcgaa ttagctgaag aatggcgcga
    25681 aaaattggtt gaagctgtag ctgaaactga tgaagaactt actttgaaat acttagaagg
    25741 tgaagaaatc actgaagctg agttaaaaga aggtatccgc cgcgcaacag ttaacgtaga
    25801 attctaccca gtactatgtg gttcagcatt taagaacaaa ggggttcaat tactattgga
    25861 cgctgttctt gattacttgc catcaccgtt agatatccca gctatcaaag ggattgaccc
    25921 taaaactgat gaagaagtag aacgtcctgc agacgacagc gctcctttct cagctttagc
    25981 atttaaagtt atgactgacc cattcgtagg tcgtttaact ttcttccgtg tgtactctgg
    26041 tgttttacaa tcaggttcat acgtacaaaa cgcaacaaaa ggcaaacgtg aacgtgttgg
    26101 tcgtatccta cagatgcatg ccaactctcg ttcagaaatc tctgaagttt acgctggaga
    26161 tatcgctgct gctgttggtt tgaaagacac aactactggg gacacactat gtgatgaaaa
    26221 gagtctagtt attcttgaat ccatggaatt cccagaacca gttatccaag tcgctattga
    26281 acctaaatca aaagctgacc aagataaaat gggtgtggct ttacaaaaac tatctgaaga
    26341 agatcctact ttccgtgctg aaacaaacgt ggaaacaggc gaaacaatca tcgctggtat
    26401 gggtgaactt cacttagata tcatcgttga ccgtatgcgt cgtgaattca aagttgaagc
    26461 taacgtaggt gcgcctcaag tatcttaccg tgaaactttc cgtgctggca ctcaagccga
    26521 aggtaagttt gtacgtcagt ctggtggtaa aggtcaatac ggtcacgtat ggattgaatt
    26581 tacaccaaat gaagaaggtg ctggtttcga atttgaaaat gcgatcgtcg gtggggttgt
    26641 tcctcgtgaa tacattccag ctgttgaaac tggtttgaaa gatgctatgg aaaatggtgt
    26701 cttagctggc tatccattag tagatatcaa agctaaactt tacgatggtt cataccatga
    26761 tgtcgattca aatgaaactg ccttccgtgt tgctgcttct atggcattac gtgcagcagc
    26821 taagaaagct aatccagtaa tccttgaacc aatcatggct gtagaagttg ttatccctga
    26881 agattattta ggtgatgtta tgggtcacgt aactgctcgt cgtggacgtg ttgaaggtat
    26941 ggaagctcgc gctggcggcc aacaagttgt tcgtgcgatg gttccacttg ctgaaatgtt
    27001 tggttatgct acaactcttc gttctgctac tcaaggtcgt ggtacattta caatgacatt
    27061 tgaccactac gaagatgtac caaaatcagt acaagaagaa atcattaaga aaaacggcgg
    27121 aaaagctgaa taatttctta aaaccggata gtcctgcaaa gagattatcc aaagagacta
    27181 tatttttaat atagtttcgt gtaaaataat tatcgatgat atgggcatgt ggtgtacctt
    27241 gtgtacatca tatacctatc agacaaataa aaaatatatt gtatttttag gaggacattt
    27301 taaaatggca aaagaaaaat ttgaccgttc taaaccacac gttaacattg gtactatcgg
    27361 acacgttgac catggtaaaa ctacattaac agctgcaatc acaactgtac tatctaagaa
    27421 aaacggcggc caagctatgg cttacgatca aatcgatggt gctccagaag aacgcgaacg
    27481 cggaatcaca atctcaacag ctcacgttga gtatgaaaca gatacacgcc actacgctca
    27541 cgttgactgc ccaggacacg cggattacgt taaaaacatg atcactggtg ctgctcaaat
    27601 ggacggagct atcttggtag tttctgctgc tgacggccca atgcctcaaa ctcgtgaaca
    27661 catcctattg tctcgtcaag ttggtgttcc ttacatcgtt gtattcttga acaaagtaga
    27721 catggttgat gacgaagaat tactagaatt agttgaaatg gaagttcgtg acctattaac
    27781 agaatacgaa ttccctggtg acgatgttcc tgtagttgct ggatcagctt tgaaagctct
    27841 agaaggcgac gcttcatacg aagaaaaaat tcttgaatta atggctgcag ttgacgaata
    27901 catcccaact ccagaacgtg acaacgacaa accattcatg atgccagttg aagacgtgtt
    27961 ctcaattact ggacgtggta ctgttgctac aggtcgtgtt gaacgtggac aagttcgcgt
    28021 tggtgacgaa gttgaagttg ttggtattgc tgaagaaact tcaaaaacaa cagttactgg
    28081 tgttgaaatg ttccgtaaat tgttagacta cgctgaagct ggagacaaca ttggtgcttt
    28141 actacgtggt gttgcacgtg aagacatcca acgtggacaa gttttagcta aaccaggtac
    28201 aatcacacct catacaaaat tctctgcaga agtatacgtg ttgacaaaag aagaaggtgg
    28261 acgtcatact ccattcttca ctaactaccg tccacaattc tacttccgta caactgacgt
    28321 aacaggtgtt gttgaattac cagaaggaac tgaaatggtt atgcctggcg acaacgtaac
    28381 aatggaagtt gaattaatcc acccaatcgc tatcgaaaac ggtactaaat tctcaatccg
    28441 tgaaggcgga cgtacagttg gtgccggtgt cgttacagaa atcaaagctt aattcactta
    28501 agttttaaag taaagcaaca tttattcgga cgtaatcgct cggaacgaag gtcttaggat
    28561 ctttgttccg agctttttta tttattgcag gatcaggaaa aaagacagga gtattataaa
    28621 tagaagaaac acgaaataaa agagtcagta ttttctaaat gaaactttat gaaaacaaaa
    28681 tgttttttac aagaaaaagc cttgctttgt gagtttatat atattataat gacaaaggtg
    28741 cgtttacttt agtgaattgc acagacgtaa tcagaatgat ttcgtcggct aagaaacgag
    28801 aggttgcgac acgcccggac gctttgccac gaacgagcgt gacggaaatt ttcgtggagc
    28861 tatgtctact tttcaaaata ggcgaaggag ggaacaagat ggcaaaacaa aaaattcgta
    28921 tccgtttaaa agcgtatgaa caccgtattt tagatcaatc agcggataaa atcgtggaaa
    28981 ctgcaaaaag aactggagct agcgtgtctg gtccaattcc attaccaact gaacgcagtc
    29041 tttacacaat catccgtgcg actcataaat acaaagattc acgcgaacaa ttcgaaatgc
    29101 gtacacacaa acgtcttatc gacattgtga acccaacacc aaaaactgtt gatgctttga
    29161 tgaagctaga cttaccatct ggtgtaaaca tcgaaatcaa attataaaac taaaacaaaa
    29221 ataatggagg tgtactcatg accaaaggaa tcttagggaa aaaagtggga atgacacaaa
    29281 tcttcactga atctggtgaa ttaattccag taactgttgt agaagctact ccaaacgtag
    29341 tactacaagt gaaaacaatg gaaacggatg gctacgaagc tattcaagtt ggttaccaag
    29401 atatgcgtga agttttatca aacaaacctg cgaaaggtca tgttgcaaaa gcaaacacgg
    29461 ctcctaagcg cttcattcgt gaattcaaaa atgttgagct aggagaatat gaagtaggaa
    29521 aagaaattac agtagatgtt ttccaagcag gagacattat tgatgtaaca ggtactacga
    29581 aaggtaaagg attccaaggg gttatcaaac gccacggaca aagccgcgga ccaatggctc
    29641 acggttctcg ttaccatcgt cgtcctgggt caatgggtcc agttgcacct aaccgtgtat
    29701 ttaaaaacaa acgtcttgct ggccgtatgg gtggcaaccg cgtaactatc caaaacttgg
    29761 aagttgtacg tgtcgatgca gaaagaaatg ttatcttgat caaaggtaat gttcctggag
    29821 ctaaaaaatc tttaattact atcaaatcag ctgtgaaagc taaataattg taggaagaaa
    29881 ggaggaacta aggaatgccg aatgtagcat tattcaaaca agatggaagc caaaacggtg
    29941 aaatcacact taacgaagaa atcttcggaa ttgaacctaa tgaaagtgtt gtttacgatg
    30001 caatcgtaat gcaacgtgcg tcattaagac aaggaacaca cgcggttaaa aaccgtagcg
    30061 ctgttcgcgg cggcggacgt aaaccatggc gtcaaaaagg aacaggtcgt gcacgtcaag
    30121 gatctatccg ctcaccacaa tggcgtggag gtggcgtagt ctttggacca acaccacgtt
    30181 cttacagcta caaacttcct aaaaaagttc gtcgtttagc aatgaaatct gtattgtcag
    30241 aaaaagttgc tgaaaacaac ttggtagcaa tcgaaggctt gaacttcgac gcaccaaaaa
    30301 caaaagaatt caaacaagtt cttgctaact tatctatcga ctctaaagta ttggttgttc
    30361 tagaaaaagg taacgacttt gctgctttat cagcacgtaa cttaccaaac gtttctgtag
    30421 taacttctga taatgtgagt gtgctagacg ttgtatcaaa tacaaaagtg ttagcaacac
    30481 aaactgctct tactcaaatt gaggaggtgc ttgcataatg aacttactag acgtaatcaa
    30541 acgcccagtg atcactgaaa aatcaatgct tgccatggat gacaagaaat acacttttga
    30601 agtggacact cgcgcaaaca aaactttagt aaaacaagcg gtagaagctg cttttgacgt
    30661 taaagtcaaa aacgtgaaca tcgtgaacgt acgtgcgaaa ttcaaacgta tgggcaaata
    30721 tgcaggatat acaaaaaaac gtcgcaaagc gatcgttaca ttgactgaag attcaaaaga
    30781 aatccaatta ttcgaagctg ctgaataagc actaatagat aactcattaa attaggaggg
    30841 aaaaacgtgg cgattaaaaa gtacaaacct acctcaaatg gtcgtcgtaa catgacaggt
    30901 tctgattttg ctgaaatcac aacatcaaca cctgaaaaat cattgttaca accattgaaa
    30961 aaccatgctg gacgtaacaa caacggccgc atcactgtac gtcatcaagg tggcggacac
    31021 aaacgccaat atcgcgtgat cgacttcaaa cgtaacaaag ataacgttgt tgcaactgtt
    31081 caaacgatcg aatatgatcc aaaccgttca gctaacatcg cgttagtaca ctatgaagat
    31141 ggagtgaaag cttacatctt agcacctaaa ggactagaag tgggtatgaa acttgtttca
    31201 ggtccagaag cagatatcaa agtcggaaat gctcttccat tagaaaacat tccagttggt
    31261 actgttatcc acaacattga aatgaaacct ggtaaaggtg gacaattgat ccgttctgct
    31321 ggtacaagtg ctcaagtact tggtaaagaa ggcaaatacg tattgatccg cttgaactct
    31381 ggtgaagttc gtatgatctt agctgcatgc cgtgctacaa tcggttctgt aggtaacgaa
    31441 caacacgaat taatcaacat cggtaaagct ggacgctctc gttggatgcg taaacgccca
    31501 actgtacgtg gtagcgtaat gaaccctaat gatcacccac acggtggtgg tgaaggtaaa
    31561 gctcctatcg gacgtaaagc accagtttct ccttggggtc aaccagctct tggttacaaa
    31621 actcgtaaca aaaaagctaa atcagacaaa cttattgttc gtcgtcgcaa aaataaataa
    31681 ttactttgac catgtgtcgc acattttgag aggaggttca ccatgggtcg tagtttaaag
    31741 aaaggacctt ttgtcgatga gcatttaatg aaaaaagttg aagctcaagc aggggttgaa
    31801 aagaaaaaag ttatcaaaac ttggtcacgc cgttcaacag ttttcccaag ttttgttgga
    31861 tataccatcg cagtttatga tggacgtaaa catgtaccag tttacatcca agaagacatg
    31921 gtaggacaca aattaggtga atttgcacct acaagaactt atcgtggaca tgctgctgac
    31981 gataagaaaa cgaaacgcta atttgagggg aggataaatc caaatggcag aacaaatcac
    32041 atcagctaaa gcaactgcaa aaacagttcg cacttcacct cgaaaagccc gtttagtaat
    32101 tgaccttatc agaggtaaaa gtgtcgcaga tgcaatttca atcttgaaat tcacaccaaa
    32161 caaatctgct ggaatcattg aaaaagtatt gatgtcagca gttgcgaatg cagaaaataa
    32221 ctttgactta gatgttgaaa acttggtagt aagcgaagct tttgttaacg aaggacctac
    32281 aatgaaacgt ttccgtcctc gtgcaaaagg atcagcttct ccaatcaaca aacgtacaag
    32341 tcatatcacg gtagtcgtat cagaaaaata aggagggata atcagtgggt caaaaagtac
    32401 atccaattgg aatgcgtgta ggcatcatcc gcgactggga tgctaaatgg tatgctgaaa
    32461 aagagtatgc tgagttctta cacgaagatt taagaatccg taaatttatt tcaactaaac
    32521 ttgctgatgc tgctgtatca acagttgaaa tcgaacgcgc aacaggtcgc gtaaacattt
    32581 caattcacac agctaaacca ggtatggtta ttggtaaagg cggttctgaa gtcgaaagcc
    32641 taagaaaaga attaaacaaa ttaactggta aaagaatcca tatcaatatc gtggaaatca
    32701 aaaaaccaga tctagatgca aaattagtag gtgaaggaat cgcacgtcaa ttagaaaacc
    32761 gtgttgcttt ccgtcgcgct caaaaacaag ccatccaacg ctcaatgcgt gctggcgctc
    32821 aagggatcaa aactcaagta tctggtcgtc taaacggagc agatatcgct cgttcagaag
    32881 gatactcaga aggaactgtt cctcttcata ctttacgtgc ggacattgat tacgcatggg
    32941 aagaagcaga tacaacatac ggaaaactag gagttaaagt gtggatctat cgtggagaaa
    33001 ttcttccaac taaaaaaaac actgagaaag gagggaaata atcatgttag tacctaaacg
    33061 tgtaaaacac cgtcgtgaat tccgcggaaa aatgcgcggg gaagctaaag gcggaaaaga
    33121 agtagcattc ggtgaatacg gtttgcaagc tgttgattca cattggatca caaaccgcca
    33181 aatcgaagct gctcgtatcg caatgactcg ttacatgaaa cgtggtggga aagtatggat
    33241 taaaattttc cctcacaaat cttatactgc caaagcaatt ggggtacgta tgggttctgg
    33301 taaaggggca cctgaaggat gggttgcacc agtaaaacgt ggtaaaatca tgtttgaaat
    33361 cgcaggcgtt cctgaagaag tagctcgtga agcgttacgt ctagcttctc acaaattacc
    33421 aatgaaaact aagatcgtaa aacgtgagga aatgggtggt gaatcgaatg aaggttaaag
    33481 aaatcagaga attaaccact gccgaaatgc ttgatcaaga aaaacaatta aaagaagaat
    33541 tgtttaatct tagattccaa ttagcaacag gtcaattaga aaacactgca cgtattaaag
    33601 aagtacgtaa atcgattgca cgcatcaaaa ctgtgttgcg tgaacaagct aagtaattat
    33661 ggaaggaggc cattaagcgt atgactgaag gaagaaatca acgcaaagtt tatcaaggtc
    33721 gcgtggtttc agacaaaatg gataaaacaa ttaccgttgc tgtcgaaaca aagaaaaacc
    33781 accctatcta tggcaaacgc atgaactatt ctaagaaata caaagtgcat gatgaaaaca
    33841 acacagcaaa agttggcgac atcgtgagaa ttatggaaac tcgtccatta tcagctacaa
    33901 aacgtttccg tttgttggaa gtagtcgaag aagcagttat tatctaataa cacgagattt
    33961 tcctatatag attgaatgca aaatctgaaa ggaggataca caacgtgatc caagcagaaa
    34021 gtcgtttaaa agtcgctgat aactcaggcg cacgtgaaat tttgacgatc aaagtccttg
    34081 gtggatctgg tcgtaaaact gctaacatcg gtgatgtgat cgttgctacg gttaaacaag
    34141 caacgccagg tggggttgtc aaaaaaggtg acgtcgttaa agccgttatc gttcgaacaa
    34201 aatcaggagc tcgtcgtaca gacggttcat atattaaatt tgatgaaaat gctgcagtga
    34261 ttattcgtga tgataaaagc cctcgtggaa cacgtatctt tgggccagtt gcacgtgaac
    34321 tacgtgaaaa caacttcatg aagatcgttt cactagcacc agaagtttta taatcttgag
    34381 acacttatca aaggaggtgc gaaacagtta tgtttgttaa aaaaggcgat aaagttaaag
    34441 ttatcactgg aaaagacaaa aacaaagaag gcgttgtact agcagcgttc ccgaaaaaag
    34501 ataaagttat tgtcgaaggt gtaaatgtcg ttaaaaaaca ccaaaaacct tctcaagctg
    34561 ctcctcaagg tggaattgtt gagatggaag cgccaattca tgtttctaac gtgatggtgg
    34621 ttgactctac tggtgtagct ggccgagttg gctacaaaga agtagacggc aaaaaagtcc
    34681 gtgtttctaa aaaaaccggt gaagttttag ataaataaaa gtttaaggaa ggagggtctt
    34741 actgaatgaa ccgcctaaaa gaaaaatatc ttaaagaagt aactccatca ttgatggaaa
    34801 aatttaacta tagctctgtt atgcaaacac ctaaagttga aaaaatcgtc atcaacatgg
    34861 gtgttggtga tgcggtatca aacgctaaaa acttagataa agcagttgaa gaattaactt
    34921 tgatcactgg tcaaaaacca atgattacaa aagctaaaaa atcaatcgct ggattccgtt
    34981 tacgtgaagg aatgccaatt ggtgcaaaag ttacattgcg cggagaaaga atgtacgaat
    35041 tcttagacaa attggtttct gtttcactac cacgtgtacg tgacttccat ggtgtaagta
    35101 aaaaagcctt tgacggtcgt ggaaactata ctttaggtat taaagaacaa ttgatcttcc
    35161 cagaagtaga ttatgattta gtagataaag tacgtggtat ggacatcgtt attgtaacaa
    35221 cagcaaactc tgatgaagaa tctcgtgagt tgttgacaca attaggcatg ccattccaaa
    35281 aataattaaa ggaggcgaac tacgtggcta aaaaatcaat gattgctaaa aacaaacgtc
    35341 ctgcaaaatt ttcaacacaa gcttatactc gttgcgaacg ttgcggacgt ccacattcag
    35401 tttatcgtaa gttccatctt tgccgtattt gcttccgcga acttgcctat aaaggtcaaa
    35461 ttcccggcgt gaagaaagct agctggtaaa aagtaaattc gcataagaag gaggtaaaag
    35521 atcaatggtc atgacagatc caattgcaga ttttctaact cgtatccgta acgcaaacat
    35581 ggttaaacat gagtctttag aagtacctgc atcaaaaatt aaacgtgaca tcgctgaaat
    35641 cttgaaacgt gaaggtttcg ttcgtgatgt tgaatacatc gaagatgaca aacaaggcgt
    35701 gatccgtgtt ttcctaaaat ttggtaaaaa cggcgaacgt gttatcacaa acttaaaacg
    35761 tatctctaaa ccaggtttgc gtgcttatgt caaagctgac gaagtaccaa aagtattgaa
    35821 cggtttaggt atcgcaatca tttcgacttc tgaaggtgtt gtcactgata aagaagctcg
    35881 tgaaaaaaat atcggcggcg aagttatcgc ttacgtatgg taatcaagta gaatctacaa
    35941 ggaggtgtct ttaagtgagc cgtatcggaa ataaagtcgt tgttatccct gaaggagtaa
    36001 cagttactca agacggaaac aacgttacag ttaaaggacc aaaaggtgaa ttgactcgta
    36061 ctttttcagc agatatcaaa atgaatatcg aaggaaacga agtaactttc actcgtccaa
    36121 acgacagtaa agaaatgaaa acaattcatg gaacaactcg tgcgaacttc aacaacatgg
    36181 ttgtaggtgt cagcgaaggt ttccaaaaag cgttagaact aatcggggtt gggtaccgtg
    36241 cacaattaca aggatcaaaa cttgtattga acgttggtta ctcacatcca gtagaaatca
    36301 caccaccagc tggagtaact gttgaagtac cagctaacac acaagtaatt gttaaaggtg
    36361 cgaacaaaga agaagttggc gaattagctg caaacattcg tggaactcgt cctccagaac
    36421 cttataaagg taaaggtatt cgttatgttg gcgaatatgt acgccgtaaa gaaggtaaaa
    36481 ctggtaaata atcgtttaga aaaattgcat agaagccagc agcaggaaaa aggcatttgg
    36541 ctgaagttta ccttcaaaaa aatacatttt tacttgtgcc gcagcttcta tttttcgaaa
    36601 cgtatttact gcttgaaata gtagtacaat aaaaataaag aggtgacaat tgtgattaca
    36661 aaaccagata agaacaaaac acgtcaaaag agacatcgtc gtgtacgtaa caatatctct
    36721 ggtactgctg agcgcccacg cttgaacgtt tttcgttcta acaaaaacat ctacgctcaa
    36781 attattgatg acgtagcggg tgtaacgcta gcaagtgcct ctaccttgga taaagaaatt
    36841 tcaggtggaa caaaaacaga agcagcacaa gctgtcggta aactagttgc tgaacgtgca
    36901 gctgaaaaag gcattaaagt agtagtcttt gaccgtggtg gataccttta ccatggccgt
    36961 gtgcaagctt tagctgaagc tgctcgcgaa aatggactag aattttagaa gaaggaggaa
    37021 taccattcat ggtttatatc gatccaaaac atttggaatt agaagaccgc gttgttgcaa
    37081 ttaaccgtgt aacaaaagtt gttaaaggtg gacgtcgtct acgttttgct gctttagttg
    37141 ttgtcggtga caaaaacgga cacgtagggt ttggtacagg taaagctcaa gaagttcctg
    37201 aagcaatccg taaagcaatt gaagatgcga agaaaaactt agttgaagta cctatggttg
    37261 gttcaacaat cccacacgaa gtaatcggtg cttttagtgg tggtagaatc ctaatgaaac
    37321 ctgctgtaga aggttctggg gttgctgctg gtggaccagt tcgtgccgta ttagaattag
    37381 ctggggtagc agatatcact tctaaatctt taggctcaaa tacaccaatc aacgttgttc
    37441 gcgcaacagt tgaaggtttg aaacaattga aacgtgcaga agaagttgca gaacttcgcg
    37501 gcaaatcagt tgaagaatta atcggataag gaggacaaca ataatggctg aattaaaagt
    37561 tactttaaaa cgcagtatta tcggacgtcc tcaaaaccaa cgcgatacag ttaaagcgtt
    37621 aggtcttaca aagattaaca gttcagtggt taagccttct aatgaagcaa ttaaaggcat
    37681 gatcaatact gtttctcacc tagtggacgt tgaagaaatt taatttagaa aaatcataac
    37741 tagaacatta aggaggtgcc aaacctatga aacttcatga attaaaacct gctgaaggtt
    37801 cacgccaagt acgtaaccgt gttggtcgtg gtacttcatc tggtaacgga aaaactgccg
    37861 gacgcggaca aaaaggacaa aaagctcgtt caggcggcgg tgtgcgttta ggatttgaag
    37921 ggggacaaac accattgttc cgtcgtttac caaaacgagg attcacaaac gtgaaccgta
    37981 aagactatgc agtcattaat cttgatgtat tgaaccgctt tgaagacgga gctgaagtaa
    38041 ctcctgttgc tttagttgaa gctggaatcg tgaaaaacga aaaagctgga atcaaagtat
    38101 tagctaatgg ggaactaaac aagaaattaa ctgtgaaagc agcaaaattc tctaaagcag
    38161 ctcaagaagc aattgaagcg gctggtggat caatcgaggt gatctaatgt ttagactatt
    38221 aaaagatgct tttaaagtaa aagacattag atcgaaaatc ctatttactg tatttgtgtt
    38281 gtttgtattt cgcctaggtg cacatattac tgtaccaggc gtaaatgctg cttcattgca
    38341 aaacctttct tctttgccat ttttcaacat gttgaacttg gtaagtggta gtgcgatgca
    38401 aaacttttcc attttctcaa tgggggtttc accatacatt actgcttcta tcgtcattca
    38461 gcttcttcaa atggacatcg tgcctcgatt tgttgaatgg tcgaaacaag gggaagttgg
    38521 tcgtaaaaaa ctgaatcaag cgactcgata tctgacatta gtattggcat ttatccaatc
    38581 tgtcggtatc actgctggat tcaatcaata cgctcaatta ggtttcgtga ataatcctaa
    38641 cgtagcaact tacgtaacga tcggtttgat tctaacagcc ggtacgatgt ttgttacttg
    38701 gctaggagaa cagatcacag aaaaaggtat cggaaatggc gtatcaatga tcatttttgc
    38761 aggtatcatt tctagattgc ctgaaagtat cagagaaatt tatgaagatt actttataaa
    38821 tattgatcct tcagacatat ggaaatctgc tatttttgtg gccattttac tagtagcggt
    38881 cttgttgatc gtgacattcg taacattttt ccaacaagct gaacgcaaga tcccgatcca
    38941 atatacgaaa cgcgtagctg gcgcgcctac aagcagctat ctgccgttga aagtaaatgc
    39001 agctggagtt attccagtta tctttgctag ttcgtttatt gctacgccaa atgctgtttt
    39061 acaagcattg agcggtagat tcggttctga aaactggtac aaagtgatga tggagatctt
    39121 taactataat acagcacctg gtgctacgat ttatacgatt ctgatcgttg ccttcacttt
    39181 cttctacgcc tttgttcaag taaaccctga gaaattagcg gaaaacttgc aaaagcaagg
    39241 aagttatata ccaagcgtac gccctggtaa ggggactgaa gagtatgtct caagattact
    39301 gatgcgttta agtacagttg gtgcagtctt ccttggttta gtggcattgc ttccaatcat
    39361 tgctcaaatg gtttgggatc ttccacaatc aatcggatta ggcggtacaa gcttactgat
    39421 cgttatcggt gtagctttag aaactgcgaa acagttagaa ggcttaatgc tgaaacgtaa
    39481 atatgttgga ttcattgagt aagaaagcgt gttgaggttt cccctcaaca cacgttctca
    39541 cacatttatt aggagggaaa acaatgaacc tcattttaat ggggctgcca ggcgcaggta
    39601 aaggaacaca agctgaaaaa atcattgatg cttatggtat tccgcacatc tcaacaggag
    39661 atatgttccg cgcagcgatg caaaacgaaa cagctcttgg cctggaagca aagtcttata
    39721 tggataaagg tgcattagtt cctgatgaag taacaaatgg aatcgtgaaa gagcgactag
    39781 ctgaaccaga tacagagaaa ggcttcttat tagatggctt tccacgtacg ctagatcaag
    39841 caaaagctct ggacgcaatg ctaaaagatt tgaataaaaa aattgatgct gtcatcgata
    39901 tccatgttgg tgaagaaatc ttggtcgaac gtctagccgg ccgatttatc tgcagcaatt
    39961 gtggagcaac ttaccataaa attttcaacc ctacaaaagt tgaagacaca tgtgatcgtt
    40021 gcggtgggca tgaattctat caaagagaag atgataaacc tgagacggtt aaaaatcgtc
    40081 tggctatcaa catcaaaaat agtgaaccaa tcttggctta ttataaagaa caaggtttgc
    40141 taaacactat tgatggtgct cgtgaaatcg atgctgtatt tgcagatgta caaaaaatca
    40201 ttgaaaaata gcacgattgc ccgtagccga cttgcattat gcagttactc ttgtcaagtt
    40261 caataaatta tgatagaata tgtcagtccg acttctagag aatcctctag atgatccatt
    40321 ttgagaattt tgaggtggga actgcagttt ccgccatttt atcgtgtgaa aatgcgaaac
    40381 aagtacaagg aggtactgtg cgtggcaaaa gaagatatga ttgaagtcga aggtacagtc
    40441 gtcgaaactt tgccgaatgc aatgtttaaa gttgaactag aaaacggaca ccaagttctt
    40501 gctactgttt caggtaaaat tcgtatgcat tacatccgta tcttacctgg tgacaaagta
    40561 acggttgaat tgtctccata cgatcttaac cgtggccgta ttacttatcg ctttaaataa
    40621 ttgtactccg taaaactaca ggaggtatta tcatgaaagt aagaccatca gtaaaaccaa
    40681 tgtgcgaaca ttgtaaagta attcgtcgta aaggacgcgt tatggtgatt tgcccagcaa
    40741 atccaaaaca taaacaacgt caaggataat tggaggtgct ataaatatgg ctcgtattgc
    40801 aggagtagat attcctcgtg ataaacgtgt agtagtttca cttacttata tctatggtat
    40861 tggtaacact actgctaaaa agatcttagc tgatgctggt gtatctgaag atgttcgcgt
    40921 tcgtgaatta acgaatgaac aaacagatgc tatccgtgca gaagtagata aattaaaagt
    40981 tgaaggggat cttcgtcgtg aagtgaactt gaacatcaaa cgtttgatgg aaatcggttc
    41041 ttaccgtgga atccgtcatc gccgtggatt gcctgttcgt ggacaaaaca cgaaaaacaa
    41101 tgcacgtact cgtaaaggcc cagctcgcgc tatcgctggc aagaaaaaat aattcttaag
    41161 tgaaggaggt taaaacttca tggcagcaaa aaaagtgaat cgtaaacgcc gtgtgaagaa
    41221 gaatatagaa gcaggtattg cacatatcca ttctacattc aataacacta tcatcatgat
    41281 cactgatact cacggaaatg cattagcgtg gtcatcagct ggttcattag gtttcaaagg
    41341 aagcaaaaaa tcaactcctt ttgccgctca aatggcagca gaaactgcta caaaagcagc
    41401 aatggaacac ggattaaaga ctgttgaagt aacagttaaa ggacctggtt ctggacgtga
    41461 agcagcaatt cgttcattac aagctacagg tttagaagtg actgcaattc gtgacgtgac
    41521 tccagttcct cataatggtg cccgccctcc aaaacgccgt cgtgtttaat gagtgccgct
    41581 cattttgagt tttatcagta acgtcattga acaagacact tttcgttttg aaaggggtaa
    41641 agataagaat gattgagttc gaaaaaccaa gaatcgcaaa aattgatgaa gaaaaagatt
    41701 atggcaagtt catcgttgaa cctcttgaaa gagggtatgg gactacttta gggaattccc
    41761 tacgtcgtat tttattatct tctttgccag gtgctgccat cactaatatt caaatcgatg
    41821 gtgtactgca tgaattctct accatcaaag gtgttagaga agacgtcact caaatcatct
    41881 tgaacattaa aggcttagcg ctgaaaatgt atggccaaga agaaaaaacc cttgaaatcg
    41941 atattaccgg acctgctaca gtaactgctg gcgatattat cgttgatagt gatgtagaaa
    42001 ttcttaacaa agatatgtac atctgtagtg tctctgaagg agctacgttc catgctcgct
    42061 taacagtgaa acctggacgt ggttatgttc aagcagatga aaataaaaaa gaagatatgc
    42121 caattggcgt tcttccagtc gattcaatct acacacctgt tcgtcgtgtg aactatcaag
    42181 ttgagaacac acgtgttgga caccgtgaag attttgataa attgacgatg gagatttgga
    42241 cagatggttc aattgaaccg ttggaagcaa tgagtttgtc tgcgaaaatc atgactgaac
    42301 atttggatat ttttgtgaac ttaactgatg aagcaaaaaa tgctgaaatc atggtcgaaa
    42361 aagaagaaac acaaaaagaa aaaatgttgg aaatgacgat cgaagagtta gacttgtctg
    42421 ttcgctctta caattgtttg aaacgtgcag gaatcaatac tgtacaagaa cttacaaata
    42481 aatctgagcc tgaaatgatc aaagtccgta acttaggacg taaatcatta gaagaagtta
    42541 aagcaaaatt gcacgactta ggtttaggtt tacgtaaaga agattaaaac cttttacgaa
    42601 ggagggaaac caacgtgagt tatcgtaaac taggacgcac atctagccaa cgtaaagcga
    42661 tgttgcgtga tttaacaact gatttattaa tcaacgaacg tattgtgact actgaagctc
    42721 gtgcgaaaga agttcgctca actgcagaaa aaatgatcac tttaggtaaa cgcggagatt
    42781 tgcatgcacg tcgtcaagct gcggctttcg tacgtaatga agttgccagc gtgcgtgaag
    42841 aaaatgagga catcgtcatt gaatcagctt tacaaaaact gttcaacgat attgcacctc
    42901 gttacgcaga acgtcaaggc ggatacacac gcattttgaa gacagaacca agacgcggtg
    42961 atggtgcacc aatggttgtc ttagaacttg tctaaaatca cactaataac atcactttat
    43021 agatgattct tttagagtgt tatgatgttg gaagatattt ttccgagtct agctcagcgc
    43081 tgctcctcaa gcgaatatcg cttggggagt aagcactcat cataaagtgt ttttttatac
    43141 cttcaattac ctgtcatgac agatatgttt gaaggcataa aaaaacattt taagcgagaa
    43201 ataattgaaa attttgtctt tttttgatag tgttagtagg aactttagga tgaagaagga
    43261 gtaatcatgg agccaattat tgaattagaa aagataaatt ataaatacca gccagatgat
    43321 cttcgccccg cattgaaaga tgtctccttt acaattgata aaggtgagtg gatcgctatt
    43381 attggacaca atggttcagg aaaatcgaca cttgccaaaa cgatcaatgg attgcttctg
    43441 ccagaatcag ggatcgtgaa agtgggaaat caaatattgg atgaagaaaa tatttggacg
    43501 atccgacaga tggttggaat gatttttcaa aatccagaca atcagtttgt tggttcgaca
    43561 gtagaagatg acgttgcttt tggtcttgaa aatcaaggga ttcccagaga agaaatgcta
    43621 gtgcgtgtga aagatgcact tgagaaagtt agaatggctg agtttgcttc acgcgagcct
    43681 gctcgtttat caggagggca aaaacaacgt gttgccattg ccggcgtggt tgccttacga
    43741 cctgatatca ttattttaga tgaagcaacc agtatgctag atccagaagg tcgtgaagaa
    43801 gtgatctcta cgatcaagaa gatcaaagaa gaaagtcaat tgaccgttat atctatcact
    43861 catgatattg atgaagcagc taatgccaat cggatactag tgatgagaca aggcgaactt
    43921 gtccgtgaag gtacaccaaa agaaattttt tctgctggtc ctgaactgat cgacttaggt
    43981 ctagatctac catttcctga aaaactgaag agcgcactga aagaacgtgg ggttgatgtg
    44041 cccagtgaat atatgacaga agaaaggatg gtggattggt tatggacatc cgttttgaac
    44101 aagtagactt cacttatcag ccgaatacac catttgaaca aagagcctta tttgacatca
    44161 atatgacgat caaagaaaac agttatactg cattagtagg gcataccgga agcgggaaat
    44221 caaccttact tcagcatttg aatgcgcttg ttaagccaac aagcggtaca gtccatattg
    44281 gagaacgaga tattcagccg gatacggata ataagaattt aaagcccatc cgaaaaaaag
    44341 ttggcatcgt ctttcagttt ccagaagcac agctattcga agaaacggta gcaaaagaca
    44401 ttgctttcgg tcctaaaaac tttggtgtca gcgaagaaga agcactagtc ctagcaaaag
    44461 aaacattaga acaagttggg ctggatgaaa gctatttgga acgttcgcca tttgaacttt
    44521 caggagggca aatgcgtaga gtagcaatcg ctggtgtgct tgccatgagg ccggaagtac
    44581 ttgtattgga tgaaccaacg gcaggacttg atccccaggg cagaaaagaa atgatggaga
    44641 tgttttggcg tcttcataag gaacagcaga tcactattgt attagttacg catttaatgg
    44701 atgatgtagc caattttgca gattatgtct atgtgttgga aaagggacga atcgttaata
    44761 gcggggagcc gcaagaggtc tttcaaaaca ttgaatggct aaaagaaaaa caactaggcg
    44821 tacctactgc caccgagttt gcagaagaat taatggctaa agggatgaac tttgctacct
    44881 tgcctttgac agctgaagaa ttagcagacg ctatcgtcca ttatgctgga ggaaatgccc
    44941 atgatgaata aattgatatt tggtcgttat atgcctggag attccttgat ccatcgattg
    45001 gatccccgag ctaaattatt agccagtttt tattttatcg gaatcatttt tttagcaaat
    45061 aattgggaaa cgtacctttt gttggcattt ttcacattac tttctgtctt cttgtcaaaa
    45121 gtagatttga aattttttat ccgaggcatt cgcccattga tctggctaat cctcttcact
    45181 gtagctttgc aggtcttgtt tacaagtggc ggagaaactt attggagttg gggtgttttc
    45241 catatcactg aatttggtgt gatgaacggc ctctttattt tctgtcgatt cgtgttgatc
    45301 atttttatgt cgactctact cacgcttact acaccgcctt tggaattatc ggatgcgatt
    45361 gagtacttgc ttcgtccatt gaaagccgta cggttcccag tccacgaaat ttcattgatg
    45421 ctgtcgattg ctcttcgttt tgtgcctaca ttgatggacg aaacagaaaa gatcatgaac
    45481 gctcagcgcg ctcgcggtgt tgattttggt gaaggaaacc tagttcagaa aatgaaagca
    45541 gtcattcctt tgctgattcc tttatttgtc agcagcttca accgtgcgga agatcttgcg
    45601 actgctatgg aagcaagagg ctacaaaggt ggggaaggaa gaacgaaata tcgtgtattg
    45661 cattggcata atagagacac gatggttatc attgcttttg tattattaac tgtgctactg
    45721 atctttttaa gaggataaac gttcagtggg ccgctatcta ttcttttctt gctgatctgt
    45781 ttgcaagaaa ggatgcaagc agtgtatgac aagaaatatt agggtctgtg gcagactaag
    45841 gtcacaggcc tctttctttt atctgaaaag aaagaacgaa aaaattttat agaaaaatca
    45901 ttattccaga taacctttta ggaacaaagg agagaaaaac atggtacgtt acaaagcaat
    45961 cattgcgtac gacggaacaa attttaatgg attccaaaaa cagccaaatg ggcgtactgt
    46021 tcaagaagaa gtagaaaaaa cattacaaaa aatggcaaat ggaaaagaaa tcacggtctt
    46081 tggttcggga aggacagatg ccggagtaca tgcgatcggg caagtaatcc attttgatta
    46141 tccagaggag cgtccgttag aacgaatgcg tttcgcgcta gatacccagt caccagagga
    46201 tattgctgta agacaagtag aaattgtttc agaagacttc cacgcaagat atttggtcaa
    46261 agaaaagacg tatcaatttc gagtggatat agggaaacca cgcagtcctt ttcgacgcca
    46321 ttatgcaagt tattttcctt acccacttga tttggaaaaa attcagcggg cgcttcctga
    46381 tttattaggg actcacgatt tcacctcttt ttgtgcatca ggaagctcga tagaggataa
    46441 aatacgtacg atctacgagg ctaagatgga ggtaaatgaa acaaaaggcg aattgttgtt
    46501 tacatttagg ggaaatggct tcttgtataa gatgatacgg atcttagtag gaacgctttt
    46561 gaaaattggc aatggccgat tgcctgaaga tagtatccca gatattattg cgaaaaaaga
    46621 tcgtaatgca gcaggaccta cagcacaccc tgaaggactt tatttgtatg aagtgaaata
    46681 tgaataagag gttatgatag aagtggtcag cttcaagaaa taagaaggta tttacgaaaa
    46741 ttacttctca aaattttgca aaatttcggc ttattttcga agaagctact tctggaacac
    46801 cgtttaagaa agaggtcgtg agcctgtcat ttaactctga gtcacaaaga gcaatttcaa
    46861 aaaacagctt ctcatctttg atgaatatcg tgacttgtgg acgaggcgtt gataagtgaa
    46921 tcatcttttt gttacctatt ttttctgtaa ccaaaaaacg atggaacgtt gttttgattg
    46981 cccttggtgc ggacagtctg aacaggttcc atcgtttctt tattttctac gtcttcttct
    47041 gtgtgtgttt cgtggttgtt cttctattgc tggatcaatc gtgccataaa aggggcgatt
    47101 gcggtcaagg taccagacat aaagaataaa caatgcaata cataggacaa aaaggattgc
    47161 acctatcgta aatccttcag gcaagtaact gaaagtgaca gtatgtttac ctgctggaac
    47221 ttttatcatc aagaatgcgt ctttgaaatt gctgaccttg actggtttcc catcaatttt
    47281 agctttccat cctttgtcat aaggaatagt tgtcaccaac atggaatctt cagcggtatt
    47341 tacagtccca gaagcttttc tgccagtggc ttccatttcg acaccttttt ctttgatctg
    47401 attcattgcg gcttgatagg ctacaacatc tagaccaacg actttaggct ccatgaaact
    47461 tatttctttc gtcccataaa aacttgcagt aaatgtcact gttgtctctt gaggataata
    47521 gccaagatca tagtattgac cagaaatgtt gatttgcgtt tttcgcgatg taccattgac
    47581 agtgatcgtc gcactagaac tttctaattg cgcaaaattg gttgggaaca aacttaagta
    47641 agcttgtgta tttgcaggca catggacttc ccaagtgagc tcttttggct ggttatctgc
    47701 tgtttctgag taagtgacgc cagtcgttgt ctttgtgatc gtcgtattca actgattctt
    47761 caaagtaggt gtatagaatg taaaatactg ttcatttaga ccagacaatg tattgatcaa
    47821 gtttgtctga ctggtcaaat tatctgtcac tggctgctca acatcattaa cggacaacgg
    47881 tgcagtaaat gctagtggca atgcattgac attctgatac agtgtatagt cgccgctttg
    47941 accagcttgg cggaagccat atttactgaa cgtgctttcg tttttagaaa tgttatattt
    48001 gattcctgta aacccatcca tcagcaaagt attattgtta taacggatat tcaaatttgt
    48061 ccctcttgaa cggaaaccta atttatccag gtaagaggaa gaattacgat ttcttataga
    48121 agaaaacaaa ctgataccac tgtaaccata gttgatcgaa tcgtttgcag atactggatc
    48181 cagattttcc aagcggtaaa acgagtcgga atcttttttt gtttcattta caagagcttt
    48241 caagtcagga taaggatcag tatataaact gcgggaagca taattccaat catcaagaat
    48301 gccatggatc atactgttcg tattgaccag tgcttcagca gacatgatca ataataacaa
    48361 tatactcaga tgattgaatg aaagtttttt atgctgataa aatcccacag caaaagcata
    48421 aatccctaag aaaaccactg tcaatacaaa ggaagtcatc gtcacatagg tgtagcttcc
    48481 ttcaggtttg atgccccatg ccaccgcaaa gagagcagct acgaccaaaa tgattcctaa
    48541 caacagccca ccatcgtctt gttctatctt ttcccatcct tttcctgcaa gcaggagcac
    48601 taagaaagag aacagatagg cataacggaa taaaaacata ttcggtgcat gcataccatg
    48661 ccagaacaaa ttcaatggaa caagataaaa acttgcgata agtatggcga aaagactgcc
    48721 gtacaaaaat ttatttttca acggtacttt ccgactggca aaataaaaca gacagaggac
    48781 taatggtagc agacctgcgt aaacgaacgg aatcgatccg tattttgtcg tgtcataaac
    48841 accaatcata tttttcatga ttagatccag ataagaagtc gcttctgttt tcaacgtagt
    48901 gatctgactc agtgcctcgc catttgaccg aagatccagc actgctggca atacaatgat
    48961 cattgaagcg ccgcctgcca gtaaagaagt gataccataa ggaacaatcg tttttttata
    49021 ttctgaccag tttgtcaata gacgggcgat aaaatataag aaagaaaata cgccaatcat
    49081 aaaacccata taaaaactgg ataaaaacaa gagtaaataa ctgataaata aaagtttcgg
    49141 ccgtttaaga tccataacac gatgaatccc caaaatcact aatggaagat aaacaaatgc
    49201 atccagccac atgatgatct ccgaatgtgc agtgataaat gagatcaatg cgtaactgac
    49261 gctaagtgca acatgccccc agcgaggaat cttgaacgta cgtgcaagaa accaaaaagc
    49321 caatccggca cagccgacct taagcaaagt cagaacatac agtgcatctg gcatcatctg
    49381 gtttggaaaa aagaacacca gtggcgtgaa gatcccgcct agatagtaag aaattaaaga
    49441 taaataattc aatcctagag aagcattcca tgtataaaaa atactttgct ttccaagaag
    49501 aacatttcgg aagctggcat gaaaattaga aaactgtgaa aaggcatcac ttgccaaaat
    49561 acttctgctg cttccaggat agattccgat acttagataa acaagtgcta aaatcaaaaa
    49621 cggaatcagg aaactagctg ctgcgtagcg tccgttttct ctaaagaatg actttaaatt
    49681 ttttttcata tttattttcc accaaatttc tatgaagttg tattcagttt atcatatcct
    49741 tgtttttctc tgcttaaaaa gagtctagtt ttcacaaaaa aataaaattt agaataaata
    49801 acttcataat ttgttcgtat aacaaaaata aacgcaaaaa aagggtagga atcaaaagtc
    49861 ccacccttaa aaatttttat taaataaaaa accgttcact atctgaacgg tccaagtatc
    49921 attcaattaa acgcgttcaa cttttcctga tttcaaagca cgagttgaca cccaaacttt
    49981 tttaggtttt ccgtcgacca taacgcgaac tttttgtaag ttaggtttaa cagtacgttt
    50041 tgttgagttc atagcgtgtg aacggttgtt tccacttttt gtcttgcgac ctgtaaagta
    50101 acaaactttt gccatggtaa tttcctcctt tgccttgatt tggagcaata gaataattca
    50161 gctcatacca gactaacata tcatatagaa tgggaatttg caagtacatt ttcatagata
    50221 caattgacaa ttgagaagaa taattgtaaa ttaaacaagg ttatacctga aattttgcaa
    50281 ggtttttgag tactttgggt aactgccttt tatttcaagt tgcgctatga taaaatatga
    50341 tagaagaaaa atgggagttt tttacccgtt aaggaggctc attcatggct gtaaaaattc
    50401 aaacgtcagc tggaaccatt gaaattacca atgatgtaat tgcaacagtt gttggtggcg
    50461 ccgcgacaga tgtgttcggt gttgtaggaa tggccagcaa aaatcaaatt aaagataata
    50521 ttactgagat tttgcgtaaa gaaaattact caagaggagt agttgtccgc caagaagata
    50581 atggtattgc tgtagatgtt tatacgatta tcagctatgg tacgaaaatc tctgaagttt
    50641 cccgcaacgt ccaagaaaaa gtgaaataca atctagaggc attattaggc gtaactgcca
    50701 attcagttaa tgtctttgta caaggtgttc gtgtactgcc agactaggca ggagactggc
    50761 tggtaactca gcagtcgatc tgaaggagga ttatctaggt gagtgtaaca gaaataagtg
    50821 caagccagtt ccaggaaatg gtccaggcag gtgcgaatcg tctgcaagta aatgcagaat
    50881 acgtcaattc attaaatgta ttccctgtgc cagatggcga tacgggaaca aatatgaatc
    50941 tatctatgac tagtggagct aaggcagtag tagattcaac ctcagaaaaa gtaggagaat
    51001 tagcagcaat gctttcaaaa ggattgctga tgggtgcgcg cggaaattcc ggcgttattt
    51061 tgtctcaatt gtttcgtgga ttttctaagc aaattccaga tgttgtctca ttaaatgctt
    51121 ctgatcttgc tgcagccttc actcatggag ttgaaactgc gtataaagca gtaatgaaac
    51181 cagtagaagg aacgattttg acagtagcta gagaagcagc gaaagctgga gaaaagaaag
    51241 caaaaagtac tgatgatgtc gttgaagtaa tgacagctgt tgtaaaagga gcaaagcgtg
    51301 ctttagctaa aactccagac ttgcttccag tcctaaaaga agtcggtgtc gtagacagtg
    51361 gagggcaagg actgctgttt gtttatgagg gctttttaag tgcattgaat ggagaattcc
    51421 aagcggatga aacatatgaa ccttctccag cagaaatgga tgatatggtc aatgcagaac
    51481 atcatcgcag tgtccaaggt caaatggcga cagaagatat ccattttggt tactgtacag
    51541 aaatcatggt aaaaatcgga gaaggaccta cagtcgatag tacattcgat tacgaagaat
    51601 tccgtaacta tttagatggt ataggagatt ctttacttgt ggtcaatgat gacgagatca
    51661 tcaaagtcca cgtgcataca gaaaacccag gagaagtctt gaattatgga caaaaattcg
    51721 gttcattagt caaaatcaaa gtcgacaaca tgcgcttgca gcatgagacg attttggaac
    51781 acgatgaaga agtgaacgag tttgcgaaaa aagaaatacc acgtatcccg tatggtatcg
    51841 tagcgatcgc tgctggtaaa ggcgtccaag agctgtttga aagtttaggc gctaattatg
    51901 ttatcagtgg tggacaaaca atgaatccaa gtacggaaga cattgttaaa gcgattcaag
    51961 aagtaaacgc agataaagtg attgtcttgc caaacaataa gaacatcttc atggcagctg
    52021 atcaagcagc agaagtagca gatatcccag tagcagttgt tccttcaaga acgatttccc
    52081 aaggattgac agctatgctt tcattcaatg atcaagcttc tttagaagaa aacaaagaaa
    52141 cgatgacaga aatgttgtct agcgttgtga gcggtcaagt cactcacgcg atcagagata
    52201 cctcaattga cggtgtagag atcaaagaag gagacttttt gggcatgatc gatggaaaaa
    52261 tcctgatctc taacccagat atcacagcaa cagcgttaag tacactagaa caaatgatca
    52321 atgaggacac agagatcgta acgatcttgg caggtgatga aggaacagtt gaacaagcaa
    52381 atgaatttgc tgagaaacta acagaaaaac atcctgattt ggaaatcgag atccaccaag
    52441 gagatcagcc tgtctatcct tatctatttt ctgctgaata atttctgtgt cagaatatct
    52501 ttctaacaca gtattcattc ataaaaggcc ttcggttagt gatcaggtat gatcgctgac
    52561 caagtccttt ttttgttaaa ggagggagga aaaatttatg cgttctttag atgatccaat
    52621 cactatgctg gcaggagtcg gagaaaaaag agcagctagt cttgccagct tgggcatcca
    52681 aacgattgaa gacttactga cttattatcc ttttcgctac gaagatattc aggaaagaaa
    52741 tctaaacgag atccaggatc aagaaaaggt tactttgaaa ggaatcgtag tctcgcctcc
    52801 tgtgatgaat cgatttggtt ataaaaaaag ccgattgcaa tttcgtatga tgcaagaaca
    52861 tgatgtgttc aacgtttctt tttttaatca accttatcta aaagaaaaag tcattttatc
    52921 ggaggaaatc gccgtatacg gtaaatggga tgcaaagcgt aaagccttga acgggatgaa
    52981 gattttaggt tctcaaacaa tggatgactt ttcgccgata tatcacgtca acaaatcaat
    53041 tcgtcaaacg acattagttg atctaatcaa aaaagggttt caagaatacg gcacattgat
    53101 tgaagaaaat ctgccaaaca accttgtgga gaaatatcga ctgcttgacc gagcttctgc
    53161 tgtaagaagt atgcattttc caaaagacca cgaagaaaac catcaagcca aacgacgtgt
    53221 cgtttttgaa gagttctttt tatttcaaat gcgtcttcaa ggattgaaaa aagcagaaaa
    53281 agcagaaacg aatggtttgg agatccttta tgatgtccaa aaattgaaac aatttactca
    53341 aaagctacct tttgaactga caaatgcaca aaaacgtgta acgaatgaaa tctgtcggga
    53401 tcttcgcagt ccgcagcata tgcagcgact tttgcaggga gatgtaggta gcggaaaaac
    53461 agtggttgcc gcgattgcgt tatacgctac cgttacagca ggtttccaag gtgcgttgat
    53521 ggtgcctaca gaaatcttgg cacaacaaca tatggaaagc ttgcaacagc tgtttgatcc
    53581 caatgaagta accatcgcat tgattacggg gtcaacgaaa gcaaaagaac gacgtgagct
    53641 ccttgaaaaa ctagagcaag gggaaattaa cgtcgtgatc ggcacacatg cattgatcca
    53701 agatggagtc gaatttcaga atttaggtct agttattacg gatgagcagc accgttttgg
    53761 cgtgaaccag cggaaagtac ttcgtgaaaa aggctggcga ccagatgtct tatttatgac
    53821 agcgactccg attcctagaa cattagctat tacagcatat ggtgagatgg atgtatctat
    53881 cattgatgaa cttccagctg gacgtatccc gatcgaaaca cgctgggtaa gaacacctca
    53941 attggacagt gtactggatt ggacgaaaaa agaactggca agaggacatc aaatgtatgt
    54001 catctgtccg ctgattgaag aatcagaagc attagatgta aaaaatgcag tggaaatcta
    54061 tgaaaaactt cgtgaactat ttgcaccaaa atatgaagtt ggcttgttac atggtaaaat
    54121 gaagaatcag gaaaaagaag taatcatgga agccttcaaa gacaaccaga tgcagatatt
    54181 agtttcgact actgtaattg aagtaggggt aaacgtgccg aacgcgaccg tcatgctgat
    54241 catggatgcg gatcgatttg gattggcaca gctgcaccaa cttcgtggac gtgttggacg
    54301 cggaagtgat gcttcctact gtatcttagt tgctaatcct aaaaatgaac taggtgtgga
    54361 acggatgaaa atcatgacag agaccaccaa tggttttgta ctaagcgaaa aagatctgga
    54421 attacgtggt cctggtgaag tatttggctt ccgtcaatct ggtctgcctc aatttgcgat
    54481 tgctgacttg gtgacggatg gaaatgtttt ggaggtagcc agagaagagg ctgcagccct
    54541 ttggcaaata aaggattggc agatgcttcc tgagtatcag cctttagcgc aaagcctcca
    54601 aatagaaaat caggataatc gttatttcga ttagcagact gtgctatact ttatactgat
    54661 gacggaaaaa ggagtggaaa caatgaaaat tgccgtagat gcaatgggcg gagatcacgc
    54721 acctcaagca attgtagaag gcgtggcttt agcgcagcaa gattttccag aagtagaatt
    54781 cttactttac ggaaaagaag cagaaatcaa gaaatactta acaaatgaaa aaaacatcac
    54841 gattatccat acagacgaaa aaatcaatag tgatgatgag ccagtaaaag caattcgacg
    54901 aaaaaagact gcatcaatgg tccttgctgc acaagcagtg aaaaacggtg aagcagatgc
    54961 tgtattttca gcagggaata caggcgcgct actagcagca gggttgttca tcgtaggacg
    55021 tatcaaaaat atcgaacgcc ctggcttgat gtctaccttg ccagtagtag ggaaagaagg
    55081 tgccggtttc gatatgctgg atcttggcgc taacgcagaa aacaaaccag aacatttgtt
    55141 gcaatacggt attttaggtt ctttttatgc acgtaaagtc cgaggtatcg gacgtcctcg
    55201 tgtcgcactc ttaaacaacg gaacagaagc aacaaaaggt agtgaagtga cgaaaaaagc
    55261 ctatgaactc cttcagaatg aaacaagctt gaattttatt ggaaacgtag aagctcgtga
    55321 gctactcaat ggtgtggctg atgtagtggt cacagatgga tttacaggca acgctgtttt
    55381 gaaatctatt gaaggaacag caatgaatat gatgaatcta ttaaaatctg ctattctaaa
    55441 tgaagggatc aaaggaaaaa tgggcgctat gcttttaaaa gacggcttac gttctttgaa
    55501 agcagaaatg gattattcca aacatggcgg tgccgttttg tttggcttga aagcaccagt
    55561 cattaaaact catggagcaa caggccccga tgctgttcgc tatacgatcc gccaaatcca
    55621 cacaatgctt gagacagatg tagttggaca attagtcgaa caatttgaaa aaagcgaaga
    55681 atagtatttg gatatctgaa gcgatccgtt ccattgaaaa aaaggtggac attcctgaaa
    55741 aatgccagta aaattagcca tggtgtaggt aattgacaag tgtatgattc ttggaggtga
    55801 aaaagttgac tcgcgaagaa gtatttaaca aagtagcgaa aattatttca aatcattttg
    55861 agatagatac cgataaagtg acggatgaat tgaacatcaa agatgattta aaagctgatt
    55921 caattagtat tatggaattc gttttagagc ttgaagatga attcggtacg gaaatttcag
    55981 atgaagacgc tgaacaaatt gaaacagtcg gtggcgcagt agattatatc agcagccatc
    56041 ttaaataatt tcaaataaaa gcaaagaagg ataaaaagct gcatgcagct ttttatcctt
    56101 ctttttttaa tctttttgac acgtaaaagt catttttctg ataattctgg cgataaacag
    56161 aaattatgtt gcaaagtaaa gcggttttct atataattat taataattca ttacacaaag
    56221 ataagaataa cctttgttat aaaacgattt attctgtgta atgtcctttt ttattaagaa
    56281 aaacttccat ttaggaagca gagaggggta ttcgattgtc cgataaccaa ttattagaag
    56341 ttcagaacct acatacagga ttccgactca aagatgacta ttacgatgca gtagatgacg
    56401 tttcatttac tttagacaaa aacgagattt tagcaatcgt tggggaatct gggtgcggga
    56461 aaagtacctt ggctactacg attatgggat tacttgatcc taataacaca aaaattacag
    56521 gtgagatttt atataacgat ctgaatttaa tcgacctgaa cgaaacgctc tataataaaa
    56581 tccgcggaaa tgatatcgga atgattttcc aagatccgtt gtctgcatta aatcctctca
    56641 tgagaatcga agaccagatc aaagaaggac tttcctatca cacaaagatg aatgcagaac
    56701 agcgtcaagc tcgtgcacta gaattgctag aacaagtagg gattcctaat cctgcgagag
    56761 ttggacgcca atatccccat gaactatcag gcggtatgag acaacgtgtc atcatcgcaa
    56821 tcgcaatcgc ctgcaaacct ccaatcgtca ttgcagatga accgacgaca gccctagatg
    56881 taaccatcca agcacagatt cttgatttac tgaaagacct tcaggaagaa acaaaaacag
    56941 ggatcatctt gatcactcat gacttaggag tcgtagcaga aatggctgat cgagtggcag
    57001 tgatgtatgg cggacagttc gttgaagtag caggtgtaaa agaactgttt gatcatccta
    57061 agcatcctta tacacgctct ttactgaact ctataccaca agaaggaaat catgatgcag
    57121 aactccatgt gatcgaaggt gtcgttcctt ctctgaaaaa catgcctcgt aaaggttgtc
    57181 ggtttgcacc acgtattcca tggataccag caagcgatca tgaagaagag cctatccttc
    57241 atgaagtcgc accgaaccac ttggtacgtt gctcctgcta taagcatttc cactttagag
    57301 acgaaaaagg agaggtgtag atgacagaat taatcacaat caaagacctg aaagttcatt
    57361 accctattcg cagtggattc ttcaatcgag taacggatca tgtatatgct gtagatggtg
    57421 tggattttat tatcgaaaaa ggaaagacat atggtttagt gggagagtct ggctctggaa
    57481 aatctactac gggaaaagcc gttgtgggat tagaaaaggt aacagccgga caaatcatgt
    57541 atgaaggaaa agatgtaacg aagcgaagca accgcaaaaa aatgggttat aacaaggatg
    57601 tgcagatgat cttccaagat tcaatgtcca gtttgaatcc taaaaagcga gtgttggata
    57661 tcattgctga acccatccga aattttgaac ggttaagcga tcaagaagaa aagaaaaagg
    57721 taaaaggact gctagatatc gttgggatgc cggaagatgc gctatataaa tatcctcatg
    57781 aattttcagg cggacaacgt caacgtctag gagtagcccg tgctgttgct accaatccaa
    57841 aactgatcgt agccgatgaa cctgtatctg ctctggatct atctgttcaa gcgcaagtat
    57901 tgaatttcat gaaacgaatc cagcaagaat acggcctcag ctatttattc atttcacatg
    57961 atttaggtgt agtaaaacac atgtgcgaca atatcgcaat tatgtacaaa ggtcgatttg
    58021 tagaaatcgg tacaagagaa gacatttata atgacccgcg acatatctat acgaaacgtc
    58081 tgctttcagc tattccgcaa atcgatgtag aaaataggga aagccacaaa gaaaatcgac
    58141 gaagagtaga acaagagtat atccaaaacc aaaaagaata ctatgatgcg actggtcgag
    58201 tctacgattt gcgtacgatc acaactacac acaaagtggc gttgaaagat ggaggtgcaa
    58261 gctaatgtgg aaaacgattc tgcgacgtgt tttattgatg atcccgcaag ttattatttt
    58321 aagtgttctg atcttcttat tagcccaagc gatgccgggg gatccattta ccggtttgat
    58381 caatccaaat caggatccgg cagtgatcga acagatgcga caagcagctg gcttgaatga
    58441 cccatggtat gtccagtact tccgttggat cggaaatgct ttgcaaggcg attttggtca
    58501 aagtttctta tacaaacgct ctgttgctga cttgatcggc gaacggatca tcaacacttt
    58561 atatctatcg atcttgacag ttgtccttac ttatttgatt gctgtgcctc tggggatgct
    58621 tgctggccgg tatcaaaatt caatcttgga taagattgtc gtaatctaca acttctttag
    58681 ttttgctgtt cctttattta tcttcggctt gatcatgcta tttgtttttg gttatcgttt
    58741 aggctggttc ccaacaagtg gatcacaaac actaggtttg caaggtggat ttatcactca
    58801 atggatagac cgtttgaaat atattctgtt accatcaatt acccaagcat ttttggcgac
    58861 tgccgtcaca atccaatatc tgcgaagtga agtaatcgat tcgaaatcgc tcgattttgt
    58921 cagaacagcc cgttccaaag gggtaccgac gaataaagta ttcagtcgac atattttccg
    58981 aaatgcagcg ttgccgatgg cttctcaaat ggggtatgaa atcacttcgt tgattgctgg
    59041 ttctgtagtt atcgaaaaga tttttggtta tccgggagtc ggaaaactat ttattgattc
    59101 catcggccaa cgggactata ccgtgatcac atccttagta ttgattttag gaatcgcgac
    59161 gctagtgggg acattacttt cagatatcat catgagtatc gttgacccgc gtattcggat
    59221 tcaataaaac caatcagaaa ggagaatgga tcgatgagtg aaaaaaacaa tacagcagtt
    59281 caagaaagta ttcctcctat ggggatacga atgattgctc gagaatttaa aaaagataaa
    59341 attgctattt tttcattagg tttgctagtg gttttattat tagtgatctt tatcggtgcg
    59401 atgctgaccg atcaagacaa agtgatgtat gttagtatct tcgacaaata cgctgcacca
    59461 ggaacagttt cgacacaagg acaaaagttc attctgggag cagatgaagg cggacgtgat
    59521 gtattaggac aattgatcat aggtgctaga aactctgtta cgatcggatt tgcgatcacg
    59581 atccttactt cgatcatcgg ggttggatta gggatcatct ctggctacta cggagggatc
    59641 attgacaaca tcttgatgcg gatcgttgat tttatcatga ttctaccgat catgctgatc
    59701 attatcgtct tcgtatcgat tatttccaga tacaatgtct ggtcctttat attcatcatg
    59761 agtgcatttt attgggtagc taaagcccga ttattccgaa gcaagacatt atctgaagca
    59821 agaagagatt atgtcagtgc ctcaaaaaca atgggaacca atgattttaa aatcatgttc
    59881 cgcgaaatca tgccgaatct aagttcatta atcattacta atttgacgat gaactttgcg
    59941 gcaaacatcg gtatcgagac aactttgact ttcttaggtt tcggcttgcc ggcaaatgta
    60001 cctagtttag gtacattgat cggttatgca agtaacggag aagtcttagt gaatcggcaa
    60061 tggatctggt tacccgcatc aatccttatt ttagttttga tgttgagtat caattatgtt
    60121 ggacaagcat tcaagcgttc tgcagatgcg cgccaacggt taggctagta tagaagcgaa
    60181 gggggaaata ggaatgaaga aaacgatttt tggatttgca gcgctgatgt ctgctgtcgt
    60241 tcttgcagca tgcgggggcg gaggtacaga tacctctgga aacaactctg gaggcaacgg
    60301 caataacaaa gaggaattaa cttttccaat tgcaacaaaa aataatgatg atgcaatcga
    60361 agacggcgaa ttagaagctg cggtcgcaac ggacagtcag tttaaaggat tgttccagtg
    60421 ggagttttac caagattcat atgatgcagc ttttatggct ccttctcatg aaccgctatt
    60481 tgcaaacgat gacgatttca gaatcacaga cgacggagct gcaacgcttg atctagatga
    60541 agatacgaaa aaagcgacaa tcaaagtaaa agacaacgtc aaatggtcag atggtgaaga
    60601 tgtaacggcg gacgatgtga ttttccctta cgaaatcatt gggaataaag attacactgg
    60661 tatccgttat gacgacactt tccgtaacat cgtaggtatg gaagaatatc atgatggaag
    60721 tgccgacaca atctccggaa tcaaaaaaat agacgacaaa acagttgaaa tcgaatataa
    60781 agaagtaaac ccaagcatgc ttcaatcggg tggtggtatc tggtcatatg cagcaccaaa
    60841 acatacgtta gaaggtgtag caatcaaaga tatggaatca agcgatcaag tacgtaaaaa
    60901 tccagtgact tttggccctt attacatgag taatatcgtt gcaggagaat cagtagaata
    60961 cttgccaaac gagcactact ggaatggtac gcctaaattg aaaaagatca cgatgaaatc
    61021 tgtaccgatg gcaagtgcaa ctgaagcatt gaactctaaa ttatatgata tgattttcca
    61081 aatgccaaca gatacttacg atacctataa agaaattgct ggctatacaa acttaggccg
    61141 tgaacaaact tcttatactt atctaggatt caagttaggt aaatggaatg cagatacaaa
    61201 gagtgtggaa tacaatccag attcaaaaat ggctgataaa tcattacgtc aagcaatggg
    61261 ctatgcatta gataataatg cagtaggtga acgtttctat gcaggtttga gaagcaatgc
    61321 gacttcattg attcctccag tattccagtc ataccatgat gatgagatga aaggattcac
    61381 acaagatcta gacaaagcga aaaaactatt agatgatgct ggctacaaag atgtggatga
    61441 cgatggttta agagaagaca aagatggaaa taaactaaca atcaactttg cttcgatgtc
    61501 cggtggggaa acagcgcaac cattggcaga ttactatatc caacaatgga aagaaattgg
    61561 tttggatgtc caatacacaa caggtcgtct gatcgaattc aattctttct atgataaatt
    61621 agaaaacgat gatcctgaaa ttgatgttta ccaagctgct tggaatacag gaactgatcc
    61681 aaatccaagt ggactatggg gaccaaatgc tgcgttcaac tacactcgtt atgaatcaga
    61741 agaaaataca aaattgatca acgatatcag ttcaagcaaa gcatttgatg aagagtacca
    61801 aaaagaagca tatcaaaaat ggcaacaata tgcatttgaa gaagcatttg cgattccaac
    61861 gttgttccgt aatgaagtat tgccagtcaa cgaccgtgtc aaagactggg attggtctta
    61921 tgatgtacca aacccatggg caaatgtttc tgttacagca gattcacgtt cataatcact
    61981 aaaaatgacc gaaaaagggc gatgtccttt ttcggttttt tgatattttt ctgtttattt
    62041 ctctaatatt caggtcaagg cgctgatttc atgacttctc caataaacgg tgttcaaagt
    62101 ccagtttctc ggtattaagt caaatttatg caaaaatatg gaaagccatt ttcacaaaat
    62161 tttttcttca tactcgaaac taaacgaatt tttcacaact tctcgtcaat cactaggatt
    62221 attaaagctt tacttacctt ttgaccgaac catttcaaat ttgacaaaaa accagtataa
    62281 taaggaagta tcgaaaaaat atccataaaa ggaatgtgga aaatggacaa ccagctgaca
    62341 aaagaactaa aagaaaacta taacatcgtt tttcacgatc taaatttgct tgaacaagct
    62401 tttacccatt catcctatgt gaatgagcat cgcaatctgc aattatcgga taatgagcga
    62461 cttgaatttt taggagatgc cgttttagaa ctgatggttt ctcagtattt attccgttta
    62521 tatcctcatt tgccagaagg aaaattgaca aaaacacgag ctgcgatcgt tcgcgaagac
    62581 agcttgtcga aatttgccaa agaatgtcac tttgatcaat atgttttgtt gggcaaggga
    62641 gaagagaatt caggaggacg tacgcgacca gcattgcttt gcgacctatt cgaagctttt
    62701 ttaggcgcgt tatatcttga ccagggattc gacacgaccc atgcattcat cgaaaaagtg
    62761 atttttccta aagtcaaagc aggtgctttt tcacatgaga tggatcataa aacaaaacta
    62821 caagaagtct tgcaaaaatc aggtgatgta tcaatcgaat accgattgat caatgaagaa
    62881 ggtccagctc atgaacgagt attttggatc gaagtttatg tagatgatca attgattggc
    62941 actggacaag ggaaatcgaa aaaattagca gaacaagctg cggcggaaaa tgcattggca
    63001 gcactgtaaa agtaagtgag ggaaagcttt gtatttgaaa cgaattgaaa tagccggttt
    63061 taaatcattt gcagacaaga cagtcattga ttttgaaaat agcgtcacag cagtggttgg
    63121 accaaatggc agcggaaaaa gcaatattac agaggctatc cgctgggtat taggagaaca
    63181 atctgctaaa agtctgcgag gcggaaaaat gccggatatc atctttgccg gttccgatac
    63241 ccgtaagcag ctgaatattg cagaagtcac agtgatttta gacaatagtg atcattatct
    63301 gccattggag tacaatgaga tcagtgtaac ccgccgttat cgacggactg gggaaagcga
    63361 gtttttcatc aataaacaaa gctgcagatt aaaagatatc caagaattgt tcttagattc
    63421 tggattagga aaagaatcgt tctcaatcat ttctcaagga aaagtagaag cgattttcag
    63481 tagtaaaccg gaagaccgtc gtgggatctt tgaagaagca gctggtgtct tgaaatacaa
    63541 gcagcggaaa aagaaagcag aacagaagct ttttgaaaca gaagacaacc tcagccgcgt
    63601 ccaagacatc atccacgaat tggaagaaca gttaactcct ttggccgccc agagtgaggc
    63661 agcaaaggag tttttacggc taaaagaaac actgactcaa accgatgtct ctttgatggt
    63721 tgctgaaatc aagacagcaa aaaaagattg ggacaacaaa caagcacagc ttgcgaaatt
    63781 caatctagaa ttaggcaaac tatctgagtc gatccaagaa caagaatcca ttttggcgaa
    63841 gcagcgtaaa gaaaatgcgc aagccgatcg tctgatcgaa aaaaatcagc aagtattatt
    63901 agatctttcg gaaaaactga agcagacaga aggacaaaaa gatgttttgc aggagcggac
    63961 aaagcataca caaaaaagct cgcaagaata tcaaacttca ttagcagaag cacaaaaaaa
    64021 ggttaaacat tttgaaaagc ttcaagaaag cttgatgaaa gcagcagcag aaaaagaaac
    64081 agagatccaa aaagctgaag caaatctcat aaaaacacag caagaattag aaaaatacca
    64141 aaaatcaacg aaagaattat tggcagaatt aagagatcaa tatgttgatt tgatgcaaga
    64201 acaagcagct gtaggaaacg aactgaagta tctagaacgt caatatatac aagaaacagc
    64261 aaaaagcaag cagacgttag ccaagcaatc ggaagtagaa gcatcagtag accgattgat
    64321 cttacaaaaa gaagaattga cacaaaagca ggcgcagcta aaatcatctt taactgaaac
    64381 aaaagagaag ttagaaatga tccaacaaaa cgggaaaaag ttccaagaag cattagcaaa
    64441 agaacagcct aaaatgtatc aattaatgaa tcaagtccag cagctacgtg ctcgtaagaa
    64501 aagccttcaa gaaatccaag aaaactattt tggtttttac caaggggttc gattggtctt
    64561 gcagcataaa cagcagcttt cgggtattgt cggagcagtg gctgaactga tcgatgttcc
    64621 tgcagatttc acgttagcta tcgaaacagc tttaggtggg gcagcccagc atgtcatcgt
    64681 tgaaaatgaa aaagatgctc ggcaagccat cacgtatttg aaacagcaaa gaggaggaag
    64741 agcaacattc cttccactga cgacaatcaa accaagacaa ttaccggctc atatattgac
    64801 acaagcagca gctgtagaag ggtttatagg gattgccagt gaacaagtca gttatcccga
    64861 tcaaatccaa actgtggttc aaaacctgct aggaacgatc cttttagcca aagacttaac
    64921 tagtgccaat gcaatcgcgc aaacgatccg ctatcaatat cgagtggttt ccttagaagg
    64981 tgatgtgatg aatgccggag gatccatgac aggtggagcg aataaacgag gaaaccaagg
    65041 cagtttgttt gtacaaaatc aagaattgaa acagttgact agtgaatttg aagaagcaga
    65101 taaacaactc caagcacaag aaaaaaaagt tcaggagctg caacaagaaa cagctcgttt
    65161 agccgaagaa caagaagttt tgcgtacacg aggcgaacaa ttacgttttg aagaacaaga
    65221 agcgacaaat cagctacaaa acatcataaa tgaacttgaa cgttttgaaa aagaaaagca
    65281 aatctcaact tttgagacac gtgaactgca gcagtttatc gaagattacg aaaagcaaac
    65341 gaacgaattg aaagacaaac aaacagatct tgaatcgcaa cgacaaaaaa tcgacgaaga
    65401 aatcaaatcg ttaagtcaag aaagcgacca gatggaagcc agaagagcac aagtacaaag
    65461 tcaaaaagca caagaacaag cagatcttgc tgtcttgaaa gagcagttta atcatctgca
    65521 gatccagctc cgcggtgccc gagtccaaaa agcagaggca accgaacgtc aagaagcgat
    65581 agaaaagcag ttggcgacat tgacagcaga cttttctgat catgaagtca cagaagaaag
    65641 tttggaaaaa caaattaacg aattatctgc tcagcgagaa acattaaaag ccgagttggc
    65701 aaaagccaaa gagcagcgag atagaaggca aaaggagatc gataagcttg aagcagtctt
    65761 ggcagagcgt aatcgtgagc aaaaagcacg actgtcggaa caatccaaat tagaagtcca
    65821 aaaagaccga gctgaaatga ttttagataa tcatttgacc tatctgcagt cagaatatca
    65881 gctgacattt gagaaagctt cccaagacta tcaagaaaca accgatatcg aagacagtag
    65941 aacaaaggtt tcatccttaa aagaacagat tgaaaaactg ggaccagtaa acttaaattc
    66001 aatcgaacaa tacgaacaag tcagtgaaag acatacattc ttagcaacac agcgagatga
    66061 tctgttagca gcgaaaaacc aattgtttga aacgatggat gagatggatg atgaagtgcg
    66121 gacaagattc aaagaagtat ttgaagctat ccgtcaagaa ttcaaaattg tctttccaaa
    66181 tatgtttggc ggcggtaaag ctgaattagt actgacggaa ccaactgatt tgctgaaaac
    66241 aggtattgag attgaagtac aacctcctgg caaaaaactg caaagtctaa gtttgctttc
    66301 tggaggagaa cgagcactta cagccatcgc gttgctcttt tccattatcc gtgtctgtcc
    66361 tgttccgttt tgtatcttag atgaggtaga agcagcgtta gatgaagcca acgtgaaacg
    66421 ttttggtcgt tacttgagcg atttccaaga tgacacacaa tttatcgtag tcacacaccg
    66481 caaaggaacg atggtcgcag cagatgtact gtacggagtg acgatgcagg aatccggtgt
    66541 atcaaaaatc gtttctgtac ggatggaaga tatcaatgaa gaggcgaaaa tcaacgaaac
    66601 gaaagtgtag gaacgaaaat gatcaaatta gtagcaatcg atttggacgg tacattatta
    66661 aatgaacaaa agctgatttc agatgagaat aaacaagcat tagcacaagc aaaacagcaa
    66721 ggggtcaaga tcgttctatg tacaggacgc cccttagctg cgatggcgca ttatctgcaa
    66781 gaattaggac tggtagatga aggtgactac agcatcactt tcaacggcgg tttggtacaa
    66841 aaaaatgata ctggtgaaat catggaaaag aaagtgatgg aagtatcaga tatccaacgc
    66901 ttatacaaac tggctcagca attggatctg ccactagatg ttttgtctga caatgtggtt
    66961 ttacagctgc ctagtgcccc aaggaagcaa tccttgtaca atgtgttgaa taagctgctg
    67021 caattccaac cagcggatat aagcgatatt acagatgaat ttgtgcttaa taaggcagta
    67081 atcgcttatg accaagaaga attagatcct aaaatcaaag aaataccagc agaattccat
    67141 gaaatgtatg agatcatcaa aacaagaagt atgcttttgg aatttatgcc aaaaggtgtt
    67201 acaaaagctt atggtatttc tttattggca aaagatcttg gtttgaaaca agaagaaatc
    67261 atggcgatcg gtgatgagga aaatgattta ccgatgatcc aatatgctgg actaggcgta
    67321 gcgatggaga atgctgtgcc tttcgtcaaa gaagcagcag atttcgtgac agccagcaat
    67381 gaagaaaatg gcgtagccaa agtgatccaa aaatttgtat tagagtaggg ggagtcaaat
    67441 gggatttttt gataaaatca agcgtgcttt tactggcgaa gagaaaacag aagaagttga
    67501 agtacaggag aagtacgaca agggtttaga aaagacgcgt aaaacatttg gtgaacggat
    67561 gaatgagttg tttgccaatt ttcgaacagt cgatgaagac ttttttgaag aattagaaga
    67621 aacacttatc ggtgcagatg taggttttga aacagcgata cgaattaccg aagcattacg
    67681 tcaagaagtg aaactcagaa atgcgaaaaa atcggcagaa gtccaaaatg cgatcatcga
    67741 gaaacttgtg gatctctatg aagcggaagg aatcaatgaa gtaaatgaac taaatatcca
    67801 agaagacgga ctaacagtta ttttgtttgt cggtgttaat ggtgtaggga aaacaacaag
    67861 tattggtaaa cttgcccatc agttcaaaaa cgaaggtaaa aaagtattga tggcagcagc
    67921 agataccttc cgcgctggag caatcgacca gttagttgtc tggggcgaac gcgctggtgt
    67981 tgaagttgtt cgtggcaatg caggaggcga tccagcagct gtcgtattcg atgctttgga
    68041 aagagcaaag acagagcagg cagatgtttt actagttgat actgcaggcc gactgcaaaa
    68101 taaagtgaac ttgatgaacg aattagaaaa aataaaacga gtaatccagc gggaattacc
    68161 agaagcaccc caagaaacac ttcttgtatt agatgcaacc actggtcaaa acgcgatggt
    68221 tcaagcaaaa caattcaaag aaacaacaga tgtgaccggt cttgttttga caaaattaga
    68281 tggtacagca aagggcggta tcgtacttgc tatccgtaat gaattgcatt taccagtgaa
    68341 attggtcggt cttggtgaag gaatcgatga cttggagccg tttgatccaa atgattttgt
    68401 cgttggattg ttcaaaggat tactaaaaga agaataaccc atgtctaaaa agcaggagct
    68461 gtgacaaaag ttgcagctcc ttgtttgaat gattgttttt aacatagctg tgtttttgat
    68521 gccttcattt ttatacttat ttgtaagcgg ttctcaaaca atttcgttct ttttcttaga
    68581 ctttttgatt ataattagat tcatatgaat tggaggtcac ttaatgatga attttaagca
    68641 attattattg catgtcaatg cgcgcccttt tatcgaccaa gctcgatttg gtatagaacg
    68701 ggaaggacag cgggttgatc ttgcaggaaa tctagcaaaa accgatcatc cagcaatctt
    68761 tggcgatcga tcctatcacc cctatatcca aacagatttt agcgaaacac aaacagagat
    68821 gatcacccct gttaccgatt ctattcccga attatttcag tatctcgctg ctgtttatga
    68881 tgtgactgct cgttctatac cgaaagaaga gatgatctgg ccattaagta tgccacctgc
    68941 cttaccggaa aaagacgaag agatcattat tgcaaaatta aaaaatttcg aagatgtctt
    69001 gtatcgacgt tatttagcaa aagaatacgg gaagcgaaaa cagatggtaa gcggtattca
    69061 tttcaatttt gaatttggcg atgagttgct aagaacattg ttcagccatc aggaagaatt
    69121 tcaagatttt tccgaattca aaacagaact ttatttgaaa acagcgagaa actttatgcg
    69181 ctatcgctgg atgatcactt atttattcgg tgcttcacca atgagtgaga agaactactt
    69241 tttagatgaa tcacatccgc aagaacctgt tcgcagtatt cgcaacagtg cgctgggcta
    69301 tacgaatcat ccaaatgtga aagtttccta tgcttctatg aaacagtatt tagcagatat
    69361 cgagcgaatg atcgaagaag ggaaactttc ggaggagaaa gaattttata caccgcttcg
    69421 tttccgaggc ggaaagaaag tcgcagattt agcaacaaca ggtgttcgtt atattgaatt
    69481 gcggaatatc gatttgaatc cttatgcaag attgggtatc aatccagagc aagttcggtt
    69541 cttacaatta ttcctgatgt acatgttatg gacagaagaa aaagaagact gtgaccaatg
    69601 ggtagcagaa ggtacgactc gaaataacaa agtagcacta gaacaaccat cagatcaaac
    69661 agaatttcat caagaaggta gagaaattct tgaaggaatg aagcaaatgc tggttgaatt
    69721 ggattggttg gattctcttt atttagtaga ggaagcattg actcaaatgg atcatcctga
    69781 acaaacgtta gcagcgaaac tctatcaaga agcacagcta tcgagtcagc aagaagttgc
    69841 tgtggcattg ggacatcaat attataaaga aagccatgaa cgtccctatc agttggccgg
    69901 ttttcgcgaa atggaacttt ctactcagat atttatgttc gatgccatcc aaaaaggtgt
    69961 ccaagtcaaa gtattagatg agtcggatca atttttgcgt ctgcaattcc aagaccatgt
    70021 agaatatgtg aaaaatgcaa acatgacaag taaggacagc tatatcgtcc cacttatcat
    70081 ggaaaacaaa acagtaacga aaaaagtctt aaaagaagct gggttccggg taccaggagg
    70141 cgcagaattt tcatccatgg aagaagcggt aaaagcttat ccgagatttg ccgagcaggc
    70201 atttgtgatc aaacctaaat caaccaatta cgggttaggt atcacgattt tcaaggaagg
    70261 agctagtctg gaagattatc aagcaggttt agccattgct tttcgtgaag acagttcggt
    70321 tttagtagaa gaatttatgc cgggaacgga atatcgtttc tttgtgatcg acggagaagt
    70381 ccaagccatc atgttgcgag tccctgctaa tgttattggt gacagtatcc gaacagtgaa
    70441 agaacttgtt gaagaaaaaa atagtgaccc tttgcgtgga acgaatcatc gtgcaccttt
    70501 agaattgatc caattaggtg aattagaaca attgatgttg aaagaacaag ggttgacgat
    70561 cgaatcagtt ccccaagcca atcaaattgt ttatctaagg gagaactcaa atatcagtac
    70621 aggtggtgat tcgatcgata tgactgatga attttctgaa gcttacaaaa aaatcgccgt
    70681 ttctgcggta gaagcactag gagctaagat tagtggtatc gatttgatta taccagataa
    70741 agaaatcgat cctacaactg ataaaaaagc atatgggatc atcgaagcaa atttcaatcc
    70801 agccatgcat atgcatgttt atccttttgc aggaaaaggc agaagattga cgatgaatgt
    70861 attgaaattg ttatatcctg aagtatttta aaagaaaaag cttttgacag attgtcctat
    70921 ttgatgtcaa tctgatcaaa agcttttttt gcatgtaaaa atttatgtgt tttttcgttt
    70981 taaaataaac gatcccagaa gctttttttc ttttttggtt tttctttttc agctggcgaa
    71041 gagttttctt ctgggtattt tttttcgata tcaatcacag gttcatttac tgcttctttt
    71101 gctgttaaga gcaatccgaa ttcctcagga tttgcagtga cgtaatcgtt gactacagtg
    71161 aaacggctat tgtttttcgt tgctagctgg atatattggt tttggacaga aaggggtaga
    71221 gccccattca agagtatgga agcatctgga tgttttttga gttcttttaa aaagttttct
    71281 ttgttttttg gttggatcat ttcagcaaca gtcatactaa gatagcagcg ttccctgaat
    71341 gtccctaaat atttatgctg ttcttcaggg ttcactaaag gtgtaccata aagtccctta
    71401 tccaaatggc tttttacatc atcttgtgcc ataaaaaata ccctccttct tctctttgtc
    71461 tttcttacga ttatagcata ttcccaataa tacctaaaac atatgaaaaa gcggttgctt
    71521 ttgttcaacg attcacttaa aataagaatg aaaatcattc tcaattagaa aggtggattg
    71581 gatgcgctac ggacgactag tagcattatt agttatttta agtagtattt cattgttcat
    71641 cggagtatcg aatgtacaat tgtcagaact gctccagtta gatgggcaaa gcttacaaat
    71701 cttgctagtg actcgtttgc cacgaacgat ttgtttgatc cttgtgggag cgaccagtag
    71761 tatttgtggg ttgatcatgc aacatttgac ccaaaataaa tttgtttcac caacgactgc
    71821 gggcacgatg gatagtgcgc gtttaggtat tttagtggct atgattttcc tacctggtgc
    71881 atccttgatt gtccgatcct tgacagcatt ttgctttgct tttgcaggaa cattgctttt
    71941 tttatccctt acgcgattgt tcctccagaa aaatcaattg atgcttccgt tgattggagt
    72001 catgttaggg aatatcattg gttcagttgc tacttttttt gcttatcaat tccagttggt
    72061 acaaaatatg acttcatggc ttcaagggaa ttttgcgact gtgatacgag gaaattatga
    72121 gttattgtat gctgttgttc cattgttgct cttggtttgg ctatttgctt accgatttac
    72181 gatcattggt ctgggcgaat cgtttgcagt aaatctggga atagattacc agaagatgca
    72241 gtttttaggc attggcttag tatcattggc tagtgcagtc atgttgatca tggtaggaag
    72301 cattcctttt atcggagtga tcattccgaa tcttgtctct agaatatatg gagatcaagt
    72361 gcacaaaaca attggcgtaa ctgctttagc aggtagtttg ttcttagtat tttgcgatct
    72421 tgtcgctcgc gtgttgattt ttccttatga aataccagtc agtgtgatcg ttggaatcat
    72481 cggtggggct atcttccttt atcttctgat aaggggacga cgatatgctt aaaaaaaagc
    72541 catctatttt tattggtatg cttgttcttg ttttatttgt tacaggaatg tacttgacga
    72601 tccatacata tggaaactgg cattttgcat gtgcattgag gagtaagaaa atttttgcat
    72661 ttatccttgt ctcgctagct gtcagcagtg ccacaatcag ctttcagaca attacgcata
    72721 accagttttt gactccttca gtattgggac ttgagtcgtt atatgtcctt gtccaaacgg
    72781 tccttttctt ctttatcgga ggagtgacga tgcttcagca gacaggtaca gtttttttct
    72841 tattgaacgt tgggctgatg gtcgggctga gtctattgtt atttttcttt cttttgaaaa
    72901 aaatgagagc gaatcttttt ttattactga tgtcagggat gattttaggt acgctttttg
    72961 gtagtgtcag taccttttta caagtcatca tggatccgaa tgaatatgat ttgcttcaag
    73021 gcagattatt tgcaagcttt ggcaatatcc agagtcagta tcttttgcct gcttctttga
    73081 tcattatcgg ctgctggtac ctgttatttc gatatcgaca tgtgctagac gttttccatc
    73141 tcggaaatga acaagcagta aacctcggga tagacacaga tcgttttgaa tttttgattt
    73201 tatgttgtgt cagtcttttg acagggacat caacggctct tgtgggtcca gttacttttt
    73261 tagggtttat tgtcgcaaat atcagttatc gtgtcttttc tacttatcgt catggtcagc
    73321 tatttatcgg aagctttctg gtagctatgc tgtttctgac aggaggacag ctcgcagtag
    73381 agcagatttt cggctggaat acaacagtga gtgtcgtcgt tgaatttgtc ggaggaattt
    73441 attttgtcac aaaattgatt cgcgaaagga agagtatcct atgattgatt tacaaaaggt
    73501 caataaactg taccatggaa aatcagtggt taaagatgta cagttaacga ttcctgaaaa
    73561 gaaattgact gcttttatcg gtccaaatgg tgctggaaag tcaacggtgt tgtcgatgat
    73621 cagtcgtttg ataccaaaag atacaggtga aatctattta gaccataacg aagtaaaggc
    73681 ttggaaatcc aatgaattag ccaaaaaatt atcgatccta cgacaatcga atgaaataaa
    73741 tgtccaaatc accgtgaaag aattagtaga atttggacga tttccttata cgaaaggaaa
    73801 attgacgaca aaagacgagg aaatcgttca ggaatcactg gaacaccttg ggttagaaga
    73861 aatagcggat caatcgattg acactctttc aggcggtcaa ctccaacgtg cgtatattgc
    73921 aatggtgcta gcgcaagaca cggattatat tttactggat gaacctttga acaatctaga
    73981 tatgaatttt gcggttcaaa tcatgcagat tttaaaaaat ttagtacaag aaatcgggaa
    74041 aacaattgtt attgttcttc atgatatcaa ctttgctgca agttatgcag acgaaattgt
    74101 tgcaatgaaa gatggacagt tatttacgca aggaacgacc caagaaatga taaaaaaaga
    74161 tgtattggat gaattatacg aaatggacat acggatttgt gagattgaag gccgcagatt
    74221 ctgtctttat ttctaaaact aacattagga gagaagagat gaaaaaatta gtagtaggta
    74281 tcttgattct agcatcattt ggtttagcag catgtggaaa tagcaacaac accagtcagg
    74341 cagacacaaa aaaaagcagc acacaaactg aaactacatt gacgataaca gatagtaatg
    74401 gagaccaaat cgaggtgcca aataatccag aaaaagtcgt cgtattcgac aatggttctt
    74461 tagatacgat ggatgctctt ggtgttggag ataaggtagt tggagcagct acaagcagcc
    74521 ttcctgagta tctttcatcc tataaaaaag tagaatcagc aggtggaata aaagaaccag
    74581 acttagaaaa aattaatcag cttcagccag atctaatcat catttctggc cgacaaagag
    74641 attttcaaaa agatctaagt caaattgctc cgaccatttt cctttcttta gatgcgaaaa
    74701 atccatggga atctttccag caaaatgtca ctgctttagg ggagatcttt ggtaagcaag
    74761 aagaagctaa aactcaatta gaggaattat ctagtgcaat cgatcagacg aaaaagaaag
    74821 cagaagctac tgacaaaaaa gcactagtca cacttgtgaa tgaagggcaa ttatcagcct
    74881 acggatctgg ttctagattc ggtttcatcc atgatttatt tggctttgaa caagcagatg
    74941 atcaaatcga agcatccact cacggtcaaa gtgtttctta tgaatatgtg ctggaaaaaa
    75001 atccggatat cttatttgta gtagacagaa caaaagctat tggtggagac gacagcaaag
    75061 atgatatttc tgccaatgaa ctggtagcac aaacgaatgc tggtaaaaat cagcagatca
    75121 tctcccttga accagatgtc tggtatttaa gcgggggcgg tttagaatca atgaaactga
    75181 tgatcgaaga tgtgaatcaa gcatttaaat agcataaata acagaggatt aaactctcat
    75241 actatgtaac aataatgttt cttacattct taaatagcaa gagcctatcc tcaaagaagt
    75301 tatcaaaaac catccgtaaa atcgtattga tgattttacg gatggttttt atttatttga
    75361 gaaatctttt ttcaacgtga attcattatc tacatcatac gggttgattc tagaatgggg
    75421 agtggcaaaa aatagtgtga tccatttttt cagcatcaag atcgcctcct ttgatttgaa
    75481 tcaaaggtac aaagcgaaac ttagataaaa cttaaattta gatattttta ttttgtaccg
    75541 atctcttctt taaacgatgt tccatctgct gcttctcggc aataagtcca ctagactaga
    75601 aaatatgaga agctattttc tgtccagcgt tcttattact caaagcaaat cgcagttgtc
    75661 acaatctctt ctaaacgatg ttccatctgc tgcttctcgg caataagccc actagactag
    75721 aaaatatgag aagctatttt ctgtccagcg ttcttattac tcaaagcaaa tcgcagttgt
    75781 cacaatctct tctaaacaat gttcaatcag ctgaccttcg gtattagctc aaagcactga
    75841 tttcacaacc tctatttagg catgtgtctc agcaagcggt tgatagttga tgatctgcat
    75901 ttttcgataa aaatcggcgg gaagcttact ccaccgtttt aataattgat agaaataact
    75961 ctcttctgct ttgattttat actcgcttaa tatcaatcca aaactattcg ttttttttga
    76021 agctaatttt ttataaatat ccaatgcttt ggttttatct tcattgacaa agagtgtttt
    76081 tacttcaata taagaaccct cgatattttg tgtttcttcg ataaaataga tgttttttat
    76141 atattccttc atagtgattc ctccaaagaa gtcttttatt tgataagttt actctaccga
    76201 agagttgtta ataatccgtg aacaaaaagt aattcttttt ccaatagttg ttaaaggttt
    76261 tttatttttt atagtatttt ttgttattta agaaaggaat aaggttaaac aaataacagg
    76321 ttgctttttg ggtctttttc cgttcaagaa actgaacgaa gaaaagggaa agttgtctct
    76381 tttgtgataa gagaaatcat aataaacgaa tgacttactt tccaataaat tgagaacagt
    76441 cagaaccaga caaattagtt gcatctgatg aataaagtga ttattctatg acatgaggtg
    76501 atacagatga aattagaagt gacaaaagaa gcacaagaag tattgaagaa taaattagaa
    76561 gcagacgatc aacttttatt agatatcgaa aacggtgacg gtccatttgc agaaagccaa
    76621 gtcagttgcc aattggatac ggcatttcga ttgatcattg tcaaaaaaga tacacaaaca
    76681 gatctaagtc tttattctgt agtggctgat acaccagttg gaccaatcaa aatcaaagac
    76741 agtgcaatac tttacatgga tgatccatcc acacttgctt tagaaccaac ttataatagt
    76801 ttacaattaa aaggaccaag cggcttgaga aaaggcaact tgcaagttgt tcgaaaagac
    76861 tagagggata aaatgggaaa attggcgatc atcagcgacc tacatgtgga catcaataaa
    76921 ttcggcgaat cagagctgat gcagctttgg caagttttgc aaaagcacaa gatcactcgg
    76981 cttcatctag ccggagatac ggctaataaa gtagaccgtt gcctagctgt tgtcgaattt
    77041 ttcgtcaata aaggattatc tacgacattt catttcggca atcacgagtt ggcagatgtg
    77101 cccaatgaac agatgatgga ccattttcca gacccacatt ttttaaatga acggtatatt
    77161 gctttaaatg agcagaccgt tcttttaggg atgaatggct ggtacgacta tcagttttcc
    77221 gaattgaaag attacgaggc aatcgtacga atgaagcgtt tgtattggta tgatcggttc
    77281 atccagcgtg ggaaaacaga tctcgaggtc aatgcagaaa tgcttgcagc tgcaaaaaat
    77341 ttgctagacc agctggaagc aaaaaaactt gaggtgattt tatccactca tttcgttcct
    77401 aaacgggcat ttatcatgta tcaatctgct ccttatgagc gttggaacaa attaaatgca
    77461 tttttaggat cagaatcatt cggagaatta cttgaccgtt attcaaatat caaacaagta
    77521 gtttttggcc atacgcatcg tcgctttgaa gataaatcca tcggtcacac gatttacagc
    77581 tgcagacctt ttggttatta ttatgaatgg cagctgaccc gagattttgt cttgaaagaa
    77641 cagttgctag acagctatga tcctatgaaa ttacgtgtcc tcttgcgtgc ccatcaccca
    77701 gcttttcagg cctatcaaac acaacatttg caagaggaat ttgaacaagc gatgacaatc
    77761 gttccgtatt gagacagcat tagtaatgtg taaaagaaaa taccttgtaa aacataagga
    77821 taagtaagag cagtagatcc atttatcgtg gatatgctgc tttttttgcg gaaaataatc
    77881 agcgaatgtt tatttgatcg gatgatttgt aactcgcaga gtactagatg caagcgtgta
    77941 ttcttttttt gaacgataat cacaaaaaaa aatataatat acatttttta tttaattata
    78001 attaatattg attgaagtct aggcagtcaa gtcacatttt gatagatagg agggggactt
    78061 acgaattatt ttaaaggcta tgacagctgt atttctagat tgtgtttgca tcaagttgca
    78121 ataaaaacta gaaatcaaat cgggctgata atcatttata actaatcgat acataggacc
    78181 aaatataggt ctatgttctt ttatttcata agtatcgtaa aacagaattt tgctatggat
    78241 taatccaatc gactgatatg tttagtaaat aaagaaagag gaatgtcaat gatgaaaaaa
    78301 gaaatcgtat taacagcagc aatgatgtta ttcagcatgg tagcaagtac gacttttgtt
    78361 tctgcaactg aagtataccc aaaggaatat aacacagaag gaacgattac atttgaagca
    78421 ggagatgagg gtgtaactcc tcctgttgat ccagagaatc ctgatcccaa taaacctgtc
    78481 gatccatcag atcctccaag ccctggaaca ggaggggcat tatcgattga ttatggatca
    78541 aaattcaaat ttgggactca aaaaatttct actgcggata aaacgtatta tgcagctgct
    78601 gatgtgatga acgatgggtc tagaaaaccg acatatgtcc aagtgacaga taggagaagt
    78661 accttatctg ggtggaaatt aagtgtctct caaccagaac agtttaaaac tgccagtggg
    78721 gatgaactag ttggagcaca gctgaaattt acgaaagggc aggctgtttc tttggttgat
    78781 ccaacatata cgccgcaaac ggtgaattct gaattaacgt tgacaccggg aggaaacaat
    78841 acgttagcaa ttaatgctaa atcaggaaca ggtgtgggga cttgggtcta tcgatttggt
    78901 gcaaatgaaa atgaaaatca agatgcggta cagctttcgg tacccggtaa atctgtcaag
    78961 ttagcgcaac aatattccac taaattagtt tggacattag aagatacacc taacaactag
    79021 tttactgaaa agaactgtta aaaataaata cgtagtcata ttgtcttgcg aggtaatcga
    79081 gcaaaaattg tcaaaggcta ggctaaattt gtttggatac gaatagttca tctaggaatt
    79141 taacgatcag gaggaaaaga tatattgaaa aagaggagga tcgtgctcat tttaagcagt
    79201 ctcttagtga ctaatatctt tccgatcata gggtactctt tggaattgaa tcagttggag
    79261 catggaaata gaagagacga agaaagcaaa ctcacttcga cattcgacag tttaatagaa
    79321 tccaaccaga cacaagaaag cagtgaggat ttaagtattt cgagtagtgg agagaccact
    79381 gacaacgtag aagctgaggg ttcggacaaa caaggactag aagatgcacc aatttctgcg
    79441 gttgagctgc ctgacgatcc caatattatt tctatcgata aaatttttca aacacctatc
    79501 ggtactagca cgtccatatt ggaaaatggg aagttactgc agttgaaccc agcagaaagg
    79561 tctcaaagag gagctatttg gtcaaataag aagattagtt tactctcgga ttttacattt
    79621 aaatcttatt tatacttagg aaatcaacga gatagagcgg gagatggcat gacctttaca
    79681 ttgactggcg atcctagaat ggctagtaat cccagtcaag ttattggatc gccaggtatg
    79741 ggaattggct catattctac tcgttctggc caaccttaca ttgcgaatgc gctctcgatt
    79801 gagtttgata cgtataaaaa tagtggttct tctgatcgaa tggatcgaga gataactgct
    79861 gataatagag ggcatggaca tgtcgctttt gtcacgccta aaccaaataa taataattat
    79921 tctggagagc atactggcgt gacggtagct cctacatttc tttctaatgg cacatggcgc
    79981 ttgttaataa ttaaatggga cgcggagcaa agaagtctta cttatgattt ggaaggtgtc
    80041 ggtcactctt ctcggattat acctgatctc attaggcagt ttggttctac agaagtaaat
    80101 tgggggttta cttcttcaac aggtactttt tttcaagaaa atgctgtcgc tgtcacgcga
    80161 cttccatcga atgtcacatc aacagctgat gtaaaagtca acgatagtga ttatggggcc
    80221 atcgctgaag ctggaggaaa cgataagata actatcagaa atacattgaa ggtcgagggg
    80281 gattttcttg aatataagaa aatgcagact agtatcgacc tcccacaaga attaactatt
    80341 cccgagcata tcttgatcaa tggaaatcaa attgatgcca aagatatctt gataaccgga
    80401 aatcgagtca cgctaaatct gacagattat tttattgctg gagatacgtt aataatcgaa
    80461 ttggagacaa ctttgcagga agtaattcct gaaaaagtac tcactatgca ttttgaatac
    80521 cttgaaaacg ggaatttgat tgagcaatcg aatgaaataa acctaaagat cgcaaagctg
    80581 aaggagatag atatccatgt ttattataaa gataaagaca gtcagattga tattgctgaa
    80641 atgaaaacaa tcactgggaa aataggagag aagtataaag aaactcctat tgatattgaa
    80701 gggtatgttt ttgactcgga ttcagcgaat acagaaggca tcttctccga aaatacagag
    80761 gatatctatt tttattacag aaaaggcaaa ctttatctct caactgctcc tcaatatgtc
    80821 aattttggaa aacataaaat atccagtaga ccattaagtg aattcggaca gttttcaggt
    80881 gggttgaaaa ttatagatga acgggctttt ggaagttgga aattacaatt gaaacaagag
    80941 aaagttctta caaatggaga ttttgagctt ccagaagctc tttcctttgt tacctctgaa
    81001 aatacaacgg ttatagggac atccgctgtt acgattttcg aaagtgatca aaagggtgaa
    81061 agcgatttgt cctctctttt agattctaca gctcatcgtg gaatcagaat agatattcct
    81121 gtagaaaacc aaagaatcgg aacctttgag gggaaactat cttggatact tgcagatgtc
    81181 ccaggaaatt aacaggaaga gaagaatata acaaaattat tgagtttcaa gaagggcaca
    81241 ggtaccatag gctcttgtgt cccacagaga caagattttg ttatagtctt ctcttacata
    81301 tgattaaagg agcgattttc ttgagaccaa aacaacaatt atttataaca ctcctagtta
    81361 ttttaggggc actttttaac aatatatcag tgtcagctag tgcatttaat ttttcagtga
    81421 cgccgataac ttcagagaat caaatcgaca agagaaaaac ttacttcgat cttcaacttg
    81481 atccggatca ggaagtagaa gtaaaagcgg aattgagaaa tgatacagaa aaagaagtga
    81541 aaatcgatat ttctgtgaat agcgcaacca ccaattcaaa tgtgatggtt gaatacggaa
    81601 aaaacgagat tgaaaaagac atgagcctga tctttgatct ggtagattat gtgagctatc
    81661 cacagatagt gacgctaaaa cctaaaagtg tccaaaccgt tgcttttcat gtcaggatgc
    81721 cgaatgagcg atttgatggt gtattggctg gtgggatcac attccaagaa atccagacgg
    81781 aaaaggacca aacagaaact aaggatcaaa gcttatcgat tgagaatgaa tacacctata
    81841 ttattgcttt gttgatgcaa cagacactga acgaagttgc tccgaacctt actcttcatg
    81901 aagttaaacc agatcaaatc aatgcaagaa atgtcatctt agcaaacgtt caaaatgatc
    81961 aaaaaaccta tatcaatcaa gtagttattg aaacaaaaat tacaaaaaaa ggacattctg
    82021 aagttttata tcaagaggaa aaagaaggat tgcagattgc gccgaataca aatttttctt
    82081 ttccaactgc tttaaatggt caaccgctaa ccccaggtga atatcacctt acaatgactg
    82141 ttttaggaaa tgaaaatgaa aatggaaaat tttcgagaaa aaaaggaaat actacgatca
    82201 actataccaa tcaatgggta tttgaaaaag attttacaat agacggaaaa gtagccaagg
    82261 aattgaacac gacggatgtt acgattaaaa aagacaataa ttggatttat atcttagtag
    82321 cttcactttt cttattgttt attttattat gcatactttt gtttgttttg agaaaaaaag
    82381 aagagaaaga aaagtaaggt taagataaca aatagtaaat ttttattatt gtaggatggt
    82441 tgggctcttt ttataacaat ataaaatata ccattttatt aataaaaatg catactagta
    82501 aatgatataa ttctaataac aggtttgatc gcgagaaagg ccaaataaaa cgctctccaa
    82561 aatgttaaaa aaaagacagg acgatgtata ttatacaaac aagaatcgct gacaacagtg
    82621 actcggatcc aggaaatcag ttttatcccc agctagttgg tgaatgcatg gaaagtaata
    82681 tacgtagaaa gagctgatga ctaatgaatt atgagttttt tttaagcaaa gaagatcaca
    82741 gaagttattc attacttaaa tatttagaag caagctcaaa tttatcagag tcaatatcga
    82801 atgttcaaga agagttgtcg ctatcgacat ttctcttgaa aaaaacgatc gataagctga
    82861 aacatgattt acaaaagttc gatctagaga aaaatttgcg agtaaccgtc agtgaattgg
    82921 atatatgtct ggaaattaat ggaaaatgtt ctagcaaagc tctgttatct cgttatataa
    82981 cggattcttt atctatgaaa atggtattgg ctttctttca ggaaaaatat atctcagtag
    83041 aaaattttgc taaacagcat cacgtgagtt attctgtggc ttataaagta ttacaaagac
    83101 taaaaagaaa tctaaaaaaa tatcaaattt tttttgaaaa gagaaagttg a
//
LOCUS       DAFEKH010000003        82072 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.003, whole genome shotgun sequence.
ACCESSION   DAFEKH010000003
VERSION     DAFEKH010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 82072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 82072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..82072
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.003"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..227)
                     /locus_tag="LP386_000190"
     CDS             complement(<1..227)
                     /locus_tag="LP386_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917462.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPAAKTRMKKGVYFLFDIVTDVP"
     gene            complement(323..1117)
                     /locus_tag="LP386_000191"
     CDS             complement(323..1117)
                     /locus_tag="LP386_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PH domain-containing protein"
                     /protein_id="HBL1917463.1"
                     /translation="MSKQCAKCGGKIGLTSYKIKDKQIVCGNCMKKAGYGMTTPYKII
                     RSLNLEDLDKDPSEKRKLNISDHTAQNNHDIGNDRMRTTEEMVEFCLKYGYGKGMTKK
                     WTTHHFNLISDQLNSDEYVIFCFVGLHNYISSTKHDNNYAYALTNKRLIVAQQKMIGN
                     NVQSIILDNLNNISKKRGVLLGTLTIDTLGKVLNVAVDKDTVDRISDSLNEIIYNLKR
                     RNISATNSNTSTISSASEIRKYKELLDDGIITEEEFNKKKQELLDL"
     gene            1763..4570
                     /locus_tag="LP386_000192"
     CDS             1763..4570
                     /locus_tag="LP386_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL1917464.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            4761..5252
                     /locus_tag="LP386_000193"
     CDS             4761..5252
                     /locus_tag="LP386_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1917465.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            5355..6344
                     /gene="manX"
                     /locus_tag="LP386_000194"
     CDS             5355..6344
                     /gene="manX"
                     /locus_tag="LP386_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HBL1917466.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            6377..7180
                     /locus_tag="LP386_000195"
     CDS             6377..7180
                     /locus_tag="LP386_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HBL1917467.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            7201..8115
                     /locus_tag="LP386_000196"
     CDS             7201..8115
                     /locus_tag="LP386_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HBL1917468.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            8198..8572
                     /locus_tag="LP386_000197"
     CDS             8198..8572
                     /locus_tag="LP386_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HBL1917469.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            8711..8956
                     /locus_tag="LP386_000198"
     CDS             8711..8956
                     /locus_tag="LP386_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBL1917470.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            9128..10192
                     /locus_tag="LP386_000199"
     CDS             9128..10192
                     /locus_tag="LP386_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBL1917471.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            10438..10863
                     /locus_tag="LP386_000200"
     CDS             10438..10863
                     /locus_tag="LP386_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBL1917472.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            10856..11305
                     /gene="nusB"
                     /locus_tag="LP386_000201"
     CDS             10856..11305
                     /gene="nusB"
                     /locus_tag="LP386_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HBL1917473.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            11402..12256
                     /locus_tag="LP386_000202"
     CDS             11402..12256
                     /locus_tag="LP386_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HBL1917474.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLSLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            12257..13594
                     /locus_tag="LP386_000203"
     CDS             12257..13594
                     /locus_tag="LP386_000203"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HBL1917475.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            13599..13823
                     /locus_tag="LP386_000204"
     CDS             13599..13823
                     /locus_tag="LP386_000204"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HBL1917476.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            13825..14715
                     /locus_tag="LP386_000205"
     CDS             13825..14715
                     /locus_tag="LP386_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBL1917477.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            14724..15542
                     /locus_tag="LP386_000206"
     CDS             14724..15542
                     /locus_tag="LP386_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HBL1917478.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            15649..16098
                     /locus_tag="LP386_000207"
     CDS             15649..16098
                     /locus_tag="LP386_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBL1917479.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            16116..17798
                     /gene="recN"
                     /locus_tag="LP386_000208"
     CDS             16116..17798
                     /gene="recN"
                     /locus_tag="LP386_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HBL1917480.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(17853..17969)
                     /locus_tag="LP386_000209"
     CDS             complement(17853..17969)
                     /locus_tag="LP386_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HBL1917481.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(18042..18998)
                     /locus_tag="LP386_000210"
     CDS             complement(18042..18998)
                     /locus_tag="LP386_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBL1917482.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            19169..19537
                     /locus_tag="LP386_000211"
     CDS             19169..19537
                     /locus_tag="LP386_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HBL1917483.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            19707..20138
                     /gene="mraZ"
                     /locus_tag="LP386_000212"
     CDS             19707..20138
                     /gene="mraZ"
                     /locus_tag="LP386_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HBL1917484.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            20159..21118
                     /gene="rsmH"
                     /locus_tag="LP386_000213"
     CDS             20159..21118
                     /gene="rsmH"
                     /locus_tag="LP386_000213"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HBL1917485.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            21123..21524
                     /gene="ftsL"
                     /locus_tag="LP386_000214"
     CDS             21123..21524
                     /gene="ftsL"
                     /locus_tag="LP386_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HBL1917486.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            21525..23717
                     /locus_tag="LP386_000215"
     CDS             21525..23717
                     /locus_tag="LP386_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBL1917487.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            23743..24705
                     /locus_tag="LP386_000216"
     CDS             23743..24705
                     /locus_tag="LP386_000216"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HBL1917488.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            24719..26080
                     /locus_tag="LP386_000217"
     CDS             24719..26080
                     /locus_tag="LP386_000217"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HBL1917489.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            26106..27194
                     /gene="murG"
                     /locus_tag="LP386_000218"
     CDS             26106..27194
                     /gene="murG"
                     /locus_tag="LP386_000218"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBL1917490.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            27209..28429
                     /locus_tag="LP386_000219"
     CDS             27209..28429
                     /locus_tag="LP386_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HBL1917491.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            28585..29910
                     /gene="ftsA"
                     /locus_tag="LP386_000220"
     CDS             28585..29910
                     /gene="ftsA"
                     /locus_tag="LP386_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HBL1917492.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            29933..31174
                     /gene="ftsZ"
                     /locus_tag="LP386_000221"
     CDS             29933..31174
                     /gene="ftsZ"
                     /locus_tag="LP386_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HBL1917493.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            31191..31868
                     /locus_tag="LP386_000222"
     CDS             31191..31868
                     /locus_tag="LP386_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HBL1917494.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            31882..32481
                     /locus_tag="LP386_000223"
     CDS             31882..32481
                     /locus_tag="LP386_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HBL1917495.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            32496..32783
                     /locus_tag="LP386_000224"
     CDS             32496..32783
                     /locus_tag="LP386_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HBL1917496.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            32832..33614
                     /locus_tag="LP386_000225"
     CDS             32832..33614
                     /locus_tag="LP386_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HBL1917497.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            33635..34342
                     /locus_tag="LP386_000226"
     CDS             33635..34342
                     /locus_tag="LP386_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HBL1917498.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            34604..37402
                     /gene="ileS"
                     /locus_tag="LP386_000227"
     CDS             34604..37402
                     /gene="ileS"
                     /locus_tag="LP386_000227"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HBL1917499.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(37451..38977)
                     /locus_tag="LP386_000228"
     CDS             complement(37451..38977)
                     /locus_tag="LP386_000228"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HBL1917500.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(38992..39639)
                     /locus_tag="LP386_000229"
     CDS             complement(38992..39639)
                     /locus_tag="LP386_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HBL1917501.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(39823..40152)
                     /locus_tag="LP386_000230"
     CDS             complement(39823..40152)
                     /locus_tag="LP386_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HBL1917502.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            40329..41057
                     /gene="sfsA"
                     /locus_tag="LP386_000231"
     CDS             40329..41057
                     /gene="sfsA"
                     /locus_tag="LP386_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HBL1917503.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            41073..42086
                     /locus_tag="LP386_000232"
     CDS             41073..42086
                     /locus_tag="LP386_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL1917504.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            42086..43363
                     /locus_tag="LP386_000233"
     CDS             42086..43363
                     /locus_tag="LP386_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBL1917505.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            43426..46128
                     /locus_tag="LP386_000234"
     CDS             43426..46128
                     /locus_tag="LP386_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL1917506.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            46280..46597
                     /locus_tag="LP386_000235"
     CDS             46280..46597
                     /locus_tag="LP386_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1917507.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            46627..46947
                     /locus_tag="LP386_000236"
     CDS             46627..46947
                     /locus_tag="LP386_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBL1917508.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            47055..48515
                     /locus_tag="LP386_000237"
     CDS             47055..48515
                     /locus_tag="LP386_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL1917509.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGPNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            48583..48804
                     /locus_tag="LP386_000238"
     CDS             48583..48804
                     /locus_tag="LP386_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917510.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            48835..49017
                     /locus_tag="LP386_000239"
     CDS             48835..49017
                     /locus_tag="LP386_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HBL1917511.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            49017..49430
                     /locus_tag="LP386_000240"
     CDS             49017..49430
                     /locus_tag="LP386_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HBL1917512.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            49553..50734
                     /locus_tag="LP386_000241"
     CDS             49553..50734
                     /locus_tag="LP386_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1917513.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(50805..50969)
                     /locus_tag="LP386_000242"
     CDS             complement(50805..50969)
                     /locus_tag="LP386_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917514.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            51123..51196
                     /locus_tag="LP386_000243"
     tRNA            51123..51196
                     /locus_tag="LP386_000243"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:51157..51159,aa:Arg,seq:cct)
     gene            complement(51265..52404)
                     /locus_tag="LP386_000244"
     CDS             complement(51265..52404)
                     /locus_tag="LP386_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL1917515.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(52703..53338)
                     /locus_tag="LP386_000245"
     CDS             complement(52703..53338)
                     /locus_tag="LP386_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917516.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINSASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(53451..54086)
                     /locus_tag="LP386_000246"
     CDS             complement(53451..54086)
                     /locus_tag="LP386_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HBL1917517.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(54120..54581)
                     /locus_tag="LP386_000247"
     CDS             complement(54120..54581)
                     /locus_tag="LP386_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBL1917518.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(54711..55142)
                     /locus_tag="LP386_000248"
     CDS             complement(54711..55142)
                     /locus_tag="LP386_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBL1917519.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(55160..55480)
                     /locus_tag="LP386_000249"
     CDS             complement(55160..55480)
                     /locus_tag="LP386_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1917520.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            55779..56555
                     /locus_tag="LP386_000250"
     CDS             55779..56555
                     /locus_tag="LP386_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HBL1917521.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            56570..56773
                     /locus_tag="LP386_000251"
     CDS             56570..56773
                     /locus_tag="LP386_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1917522.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            56789..57127
                     /locus_tag="LP386_000252"
     CDS             56789..57127
                     /locus_tag="LP386_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HBL1917523.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            57114..57293
                     /locus_tag="LP386_000253"
     CDS             57114..57293
                     /locus_tag="LP386_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917524.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(57336..57806)
                     /locus_tag="LP386_000254"
     CDS             complement(57336..57806)
                     /locus_tag="LP386_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917525.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            57893..58591
                     /locus_tag="LP386_000255"
     CDS             57893..58591
                     /locus_tag="LP386_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HBL1917526.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            58769..59110
                     /locus_tag="LP386_000256"
     CDS             58769..59110
                     /locus_tag="LP386_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917527.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            59103..59774
                     /locus_tag="LP386_000257"
     CDS             59103..59774
                     /locus_tag="LP386_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HBL1917528.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            59780..60466
                     /locus_tag="LP386_000258"
     CDS             59780..60466
                     /locus_tag="LP386_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917529.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGG"
     gene            60469..61218
                     /locus_tag="LP386_000259"
     CDS             60469..61218
                     /locus_tag="LP386_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1917530.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            61230..61499
                     /locus_tag="LP386_000260"
     CDS             61230..61499
                     /locus_tag="LP386_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917531.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDGTQLRNLAYTKLLFIDCVKGLQKHLNELEQV"
     gene            61505..61669
                     /locus_tag="LP386_000261"
     CDS             61505..61669
                     /locus_tag="LP386_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917532.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            61662..61961
                     /locus_tag="LP386_000262"
     CDS             61662..61961
                     /locus_tag="LP386_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917533.1"
                     /translation="MDKKAAMQRIIELTYSEDWQEDKKIVAEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAKQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            61961..62263
                     /locus_tag="LP386_000263"
     CDS             61961..62263
                     /locus_tag="LP386_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBL1917534.1"
                     /translation="MDELIAKVEQWAKDKGLDQADFSKQMLKTVEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLDFAYDEIKGRTGKMVNGVFVKSSDLK"
     gene            62303..62668
                     /locus_tag="LP386_000264"
     CDS             62303..62668
                     /locus_tag="LP386_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917535.1"
                     /translation="MIDAKQVQKQKDGMLMFEAYVLPFLNQFEVLECSASGEELEYVV
                     IRETKENVQKLNEFLCTINCWDMIAPGFLCPAMGEFLEYCRLEDAGTLDLAYLVYNYL
                     NINTDHLWFGTAERKWVVR"
     gene            63158..63298
                     /locus_tag="LP386_000265"
     CDS             63158..63298
                     /locus_tag="LP386_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917536.1"
                     /translation="MNEIAADHELSETALIDQIELARQYFVPYADTWSKHKNDIIFPE
                     EQ"
     gene            63295..63483
                     /locus_tag="LP386_000266"
     CDS             63295..63483
                     /locus_tag="LP386_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917537.1"
                     /translation="MRATDPVIILEEAKFIWTHEEIEQARLLFSQGVKPSKVAEIMGQ
                     KILDVGLLLLHLAEKNLI"
     gene            63491..63685
                     /locus_tag="LP386_000267"
     CDS             63491..63685
                     /locus_tag="LP386_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917538.1"
                     /translation="MMIQLAGIQTGKIYFSGESKSEANQWLLKTYTNNKKLRKKYPDL
                     LLKDDQIMPEPMILTRKEGS"
     gene            complement(63718..63930)
                     /locus_tag="LP386_000268"
     CDS             complement(63718..63930)
                     /locus_tag="LP386_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917539.1"
                     /translation="MNINNLVKLVEQRFKESGLEQLKKDNSPELFSNFTEDDIPTLKQ
                     LKYYSDYWTQTRENELNLEKLIIKKK"
     gene            64055..64258
                     /locus_tag="LP386_000269"
     CDS             64055..64258
                     /locus_tag="LP386_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917540.1"
                     /translation="MVKVREQFKIVSDEDNVYKIKIVNINEYREADHKYLVDLYMNDK
                     YLGEGFCGDSLFDDERILKEETE"
     gene            64255..64527
                     /locus_tag="LP386_000270"
     CDS             64255..64527
                     /locus_tag="LP386_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3850 domain-containing protein"
                     /protein_id="HBL1917541.1"
                     /translation="MIHELKILPEYFEAVTSGRKQFEIRKNDRDFKVGDQLILREYKK
                     YIKHELPGLTRPTFSYTGDSYKAEITYITDYMQKSGYVVLGIKGVN"
     gene            64528..64713
                     /locus_tag="LP386_000271"
     CDS             64528..64713
                     /locus_tag="LP386_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917542.1"
                     /translation="MKVYILAITEGTWMFPVGSGKIYKSKTAAYKAFEKYKKENGGGT
                     NAKILVADNWHEEGERN"
     gene            64700..65047
                     /locus_tag="LP386_000272"
     CDS             64700..65047
                     /locus_tag="LP386_000272"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917543.1"
                     /translation="MNVIDLPVHFRGTNYFYASNLIQKKMSKDERKILANFYLVLKIE
                     QNVFSERRIVWEKQNQRLRRKNDVWNKRQSRMERLRKNKKATPFEIAAQYYSTIRGGV
                     CEISLVKRLPRTR"
     gene            65007..65483
                     /locus_tag="LP386_000273"
     CDS             65007..65483
                     /locus_tag="LP386_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HBL1917544.1"
                     /translation="MRFHWLKDYQELDEQILYLKWNLNKSKLELNRWVCGDLANVRIE
                     KNSRTSSLEENIQKIENELELLIEQKEEMLLLIDSFSGIDNQIVKMKYVDQMSLEDIA
                     ESVGYSSSYVRQRHAEIRKTLNFLDEYEHRQADRLKKENEIDFYNSEKYKEQLSLF"
     gene            complement(65629..66357)
                     /locus_tag="LP386_000274"
     CDS             complement(65629..66357)
                     /locus_tag="LP386_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HBL1917545.1"
                     /translation="MRGVLMLQEVNIKYRDRQNTETIYLPNSCPHCGNIMTPYVYFGV
                     SSYSAFDNDRIFGVLVQCINDECNKFYSLQFINTFNEDEGYSENILIKDYYRPPIKID
                     LPENIEKVSPTFVDIYTQATQAKSEQLEQIAGVGYRKALEFLIKDYAISKNSEDEDKI
                     KKMLLGKTIENYLNDFPKLQRLAKAATWIGNDETHYVRRHTNKDVHDMDAFIKSAAQF
                     IAADYDADLADQFINGNNFMPTTN"
     gene            66405..66683
                     /locus_tag="LP386_000275"
     CDS             66405..66683
                     /locus_tag="LP386_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917546.1"
                     /translation="MNDFHEAVLSIEVESSLAKVYKKAIEAENSPYRENWNGNHAHVQ
                     VENDDYRTGMNTLVISLLSHTLPNLQETIEWYERMGAKVIRTNYKGEN"
     gene            66685..67071
                     /locus_tag="LP386_000276"
     CDS             66685..67071
                     /locus_tag="LP386_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917547.1"
                     /translation="MAMIKIRTSISGTEYWDSEKKRTVVVPKDQEPNFEVKEEKGILS
                     DGKSFVAVNGELIAHSSEILDSDGNTAANFDGDEATNDQSTEDTDELDNMTAKELRAY
                     AKKHGIDIPGAIRAKGDIINLIREVE"
     gene            67068..67448
                     /locus_tag="LP386_000277"
     CDS             67068..67448
                     /locus_tag="LP386_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBL1917548.1"
                     /translation="MKYCQFDGCTNKIAKGIYCTEHKRSSRSRKKKQQAKSVYHHENK
                     PFYRTQAWKDMRQFIYEREGGHCQRCGQFIFGKRAHVHHIVPIKDNELLKLDPNNLML
                     LCSKCHPIVENETEDKKVFPSYFN"
     gene            67560..68012
                     /locus_tag="LP386_000278"
     CDS             67560..68012
                     /locus_tag="LP386_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HBL1917549.1"
                     /translation="MTTKAQRKAIIDEKVSAEKARILEIMNLSDLYTITLDPLIESYL
                     DIFEIYQHKYLLWKEKGFPETQKFTNKSGATNQSKHPLAQQVETWADKKMKALDLLGL
                     TNKAKTGRLIAGGSTARKDEEITRPEVKPVDELAAHRNKWRKKAGAEK"
     gene            68009..69736
                     /locus_tag="LP386_000279"
     CDS             68009..69736
                     /locus_tag="LP386_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBL1917550.1"
                     /translation="MIEPGVNYADLFAKEVRKKPKKYPKTVRLAIDRWYQWKKRKDIW
                     FDVDRANEMMDWVESFIVHTKGEMVGKPFLLEPWEKFIYSWIYGWVKENEKGQIVRVT
                     REAYVQIPKKNGKTLIAVGSLGYAMYGEGALSVDCYACASDFAQAQYAAKPFAVTILN
                     NPILLEGTKIFRGPKGTVSSITYDYIHEDMAYSNKFIVQTKNIDNIEGSNPYFVLNDE
                     LHKQEKMEQYDNFKSAQISLPQPLMFNISTAGKGSSSVGMRVYREAKEVLKRDDNDSN
                     FVLIYEPNKNYDWTDRKVWEMCNPNWGISVDLSALESAFKTAQRSAHSKAEFLTKHLD
                     VFVNGADNFFEQDQVEPCLVTTQELGDLSGEPCYIGLDLSRTRDLTCVSLNFPTWDED
                     GKAVLKVKQLYFIPNEDLEFREKEDNVPYSDLAEQGFVEFCDGKMIDQDQILQYIEDC
                     MNLYDIQQVNYDPAMSDKLVEKLENLGLECVEVAQYPKVLNAPFDDVERLFYEKRIQF
                     DNPLFLYCTLNVVAITNINGQKAPSKRQSKKKIDGFVAFLCGHKETMNQMTDIDSDEL
                     DDYLSSIYR"
     gene            69800..70987
                     /locus_tag="LP386_000280"
     CDS             69800..70987
                     /locus_tag="LP386_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBL1917551.1"
                     /translation="MEKRGYIEDIFGHYTRYGQRYVTDSSIMESSDVYELVQDISNQV
                     ALATPIVIGPDGNEVKDHHLLNILKSPNDYLTGFEFTKLETNTLLINGETFPLTDRDQ
                     LHLAYGVTTKINERLQEEFEMNGQKIPGQMIRHIKNIGTDSLKGAGIIDLARNTLEGV
                     LSAEKVLTDKYTKGGLLAFMLKLDAHINPNNSAQTKIVKAILDQLEGTQNESDHSVKM
                     IPLGKGYSIETLKSPVDDAAILNYLGVYKKDLGKFLGINVDTYQSLMKTDIEKAMMYL
                     HNKAIKPILKNKSEHYTALFFMPNSGYRVEWKINILDFVPYSTKTNIGYNIVRTGITS
                     PDNVAEMLGFPKQNTPETQAIYISNDLSRIGQKNATDDSLPTNDQDLKGGDGNEEEGN
                     SHD"
     gene            70959..71528
                     /locus_tag="LP386_000281"
     CDS             70959..71528
                     /locus_tag="LP386_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HBL1917552.1"
                     /translation="MKKKEIRTIDITNLSTRSDEETHTRTISGYAAVFNSQTLLWDDL
                     SEVIVPGAFSKAISNSDVRCLFNHDWSNVLGRTKSGTLRLEEDERGLKFEVDLPDTTV
                     ARDLVKSMERGDINQCSFGFVPTEETWDYNSEPMLRTIHEVELYEVSIVPLPAYEDTE
                     AALRSRDELEKNVEERKKLIKKINQALEA"
     gene            71541..72905
                     /locus_tag="LP386_000282"
     CDS             71541..72905
                     /locus_tag="LP386_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBL1917553.1"
                     /translation="MDKELLKKMKARREQRLTELREKVESGELREADLEAVKEEIDSV
                     IDELNGIKDELGADSGTDETDDNTDDQSNSTDSDESRSGEDNDQEEDSDSEDSSENRS
                     GMITQQQRDGLLGSIKNGLEARAKMTKKQKDQQLRKAFANFVAGNISEAEARALGIEA
                     GNGSVTVPEVIASEVITYAQEENLLRKYGTVVRTSGDVKYPILVKKADANVNKKERST
                     DIAETAIQFDEILLNPAEFDALATVTKKLLKMSGVPVEDIVVEELKKAYVRKEINYMF
                     NGDDAGNENPGALAKKAVAFKKPLDLTASGAGQKLYDALIEFKNTPVTEVMKKGRFII
                     NRAALTAIEKMKTDDGFPLLRPFTQAEGGIGYQLVGYPVDWTDAADKKGEPDTPVLYF
                     GDFSAFKIQEVIGALEIQKLVEKFSGKNQIGFQIYNLLDGQLVYSPFEPAVYRYEITK
                     PVGG"
     gene            72907..73188
                     /locus_tag="LP386_000283"
     CDS             72907..73188
                     /locus_tag="LP386_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBL1917554.1"
                     /translation="MEEQTKELSLEEKFKSHIHFEEGMDDSLLSFYLNMAKDYVKTAT
                     GGQQEYLILMVAGIAYEYRVSEDELDKAMNAMTPFIVQGAIQNAEETDQ"
     gene            73166..73492
                     /locus_tag="LP386_000284"
     CDS             73166..73492
                     /locus_tag="LP386_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBL1917555.1"
                     /translation="MPKRQTNNLRWKAELLDIKTGTDGNDRPTTIYEFKRLIFYEELG
                     VTSQEKYLSQQAKTDVVRRIKVRWDKSITEKLSALKIDSVTYNITRIYTNPDAREMEL
                     SLAYVD"
     gene            73482..73820
                     /locus_tag="LP386_000285"
     CDS             73482..73820
                     /locus_tag="LP386_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917556.1"
                     /translation="MSISFDELKTALKSTKLAVFRDKARLGTMYPYIVYSNVSNSKKM
                     ASGKVYKKLPYYQVSFFTLGTEQDLVVIEQALQNAGIPYSDFTGIQGDENDDTVTNYY
                     TYVRCVENAK"
     gene            73810..74175
                     /locus_tag="LP386_000286"
     CDS             73810..74175
                     /locus_tag="LP386_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBL1917557.1"
                     /translation="MPSNKNGFSEISDYLGNLSKVDPKKLSLESLEEAANFYLKQLLP
                     NIPKSLLKKKHMRDQIKVVVENDQVKVQFEETAFYWRFAENGTTNQRAQHFASGTYEQ
                     NKEKIEEIMTRKILDLWEG"
     gene            74182..74808
                     /locus_tag="LP386_000287"
     CDS             74182..74808
                     /locus_tag="LP386_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL1917558.1"
                     /translation="MGKQDTFYFEGLDDILIAMMATPDSVGTAPTYSEVLRLPIATKI
                     GVKGNGTALEKWASSKMFRRVSRETKHELALDHVGIPIEVMDEIKGLVAKSGVTFSKN
                     TAREFPYFAFGFIGNIENGGKKAVWYPNTQLSNVIDEEYATAEEETKIDDVTANLVSI
                     GLKYNNVMYASFDSNRDGASLELFNKFIAQPVYDEEQWKTLAKVGGAG"
     gene            74808..75272
                     /locus_tag="LP386_000288"
     CDS             74808..75272
                     /locus_tag="LP386_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917559.1"
                     /translation="MARLSDYGIHVEDLKNSAVVIIQGAEFPISFTMQTMEFIADVYG
                     GDYSQFESDMNAMLSKKEGQISSANLSPSDLKIMRALIYAMLRTGGLEEDPETIFKFL
                     GMSGEVLSAYSTCMEIFASQTFQVEDLKKSKKPQDFQKAQAKRKKNKKNRKR"
     gene            75467..77776
                     /locus_tag="LP386_000289"
     CDS             75467..77776
                     /locus_tag="LP386_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBL1917560.1"
                     /translation="MAGKESDVVLNFKTNGEVSYSKTIKEINKEMNLAAAEYKNQVSA
                     MDKDATQTEKLRAAKQKLEKQLGLAEQRSQMLREEYEKSVKETGEYSAESEKLYKQLL
                     NSETGENKLRTALEQTNDALKEQGDVSVDTAKKLQKIEETGEKVKGVGEKMSVGVTAP
                     IVAAGAAGLAAFGEVDEALDTIITKTGATGDQADRLSQSFKNVGSNTHLPLQTVGEAI
                     GEVNTQFGFMDKKLEDSTNYLLQYAEINDTDVSQSAISARQAIDAYGLEYDDLNSVLD
                     VTTKTSQNTGQSVDDLMQKAIDGAPQIKQLGLSFGEGVTLLGQFEQSGVDSSAALSSL
                     SKATVAYAKDGKSLSQGLEELQDKVKNAGSETEAINAAAEVFGTKGGPRMADAIRRGT
                     LNLEDLAKTAGESGGAVGDTFDATLDPIDQADQAMNNAKLAMADVGEAVQVSLLPFFE
                     KATSLLQEFSKWWGSLDQDTKNWIITIAGIAAAVGPVLIVLGSLMGSVTKIVGEVKSF
                     IGVWQGLAGLFGMSGGWFALAVIAIGALVTGLIWAYNNVKWFHDGVNSFFKGVSDVAV
                     EIFNFLSGYFGGFFDGVIANFNNFYNAGKRIFSGFLDFITGVFTGNWSKAWQGLVDIF
                     GGIFDGIVAVGKAPINAMIGLINGFIGGLNNIKIPKWVPGVGGKSFSISKLPYLAQGG
                     HLINGQAIVGEAGPELLTAKNGKTTVTPLSDEEKRKGISGRVSGGSIEQHIHIGKVDA
                     NNPSELDRMNRKFAKANKQAIRDLGGVPI"
     gene            77788..78492
                     /locus_tag="LP386_000290"
     CDS             77788..78492
                     /locus_tag="LP386_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL1917561.1"
                     /translation="MNPDEPNFIWKNRNAVIDMNCIIEAELPDIMPNKRYETYTIQGR
                     SGELTETFDDYEPFDLEIEGITIPHSKLREVKRWLTGKSQLITHNDPDKYLEAICSMD
                     KEVPFENEWGFFYTFDVTFRCQPLKRKIGEAPKIFHSSVMDIFDHGDEIAHPYLEIES
                     NGGDITIAVGDKSLTILNTLAATIVVDTQLGKAIQEGLNLFTRGDWPVLQPEWNQVKI
                     SGKFKEVRFWNRSVYL"
     gene            78489..81248
                     /locus_tag="LP386_000291"
     CDS             78489..81248
                     /locus_tag="LP386_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL1917562.1"
                     /translation="MTQEFIYAYKKMPDDLSVNGASLVDWEDLPEINRVLNGQYRFYG
                     NYSRSGQYRSYLKKGNFIKAKVPDGSWQYFEIYNVKKNLTSVSVTARHIGFMANKNFI
                     VKSFTDNGNGSQIMTNLKNSLAFDQKFNYLSNVGTTHQFTARQVAPVEAIIGSNNGNQ
                     NLTGVTSAELDMDNYDLKLVKQIGSDNGFRIDFGINLEAIEEEIDEESIVNSLYLVGG
                     VPDNDYDEDKEPIEYGYLEIDGVTNENRRIAKRENGDCKTVDELIKWGKTLFDNDRIH
                     EPKATHTVSMVALEHTLEYGDMYQELASLHFGDVAHVRAKELDIEIKERMVEYTYFPT
                     LGKYKDIVLGNDLSLYTSAVNTQAQELKKKIDNRTETLVQNVLNATAWITGNSGGHVV
                     FRPEKAPSEILIMDTPNVANAKRVWRWNLNGLGYSDNGVNGPFGIAITSKGEIVADFI
                     KVGTINAEVFETSFNAYGDVLKLVKGTLQIWNENKKIMELTKKGMEFWNRKESIGTIG
                     TTDSAGNPFPNAVTPTPLEENSLVIRTNGDGKYILISPTAEKGFVLLGNGKAYYFGDL
                     DIQGKLTVRGKEVIPGQNGGPSGGGETPGGYPDELKTDAEKRAWRIYDILCNNGFTKQ
                     SACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWDGKVYVQNLFN
                     AAGIKEPITSLDAQVRLLIWTFTNGQWMGVVQPTTVDGFKACTDPRQAAYAFERNYER
                     PAATHPERQDYAVNWYNKFKDLKPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYSG
                     YLGGCGMGAGTKYGLTHVIGNTSAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIINW
                     ARGGQVGSWFADGTYGHTGVIRGLANGRMQTYEQNTELGMICGKLDRQYYSASAISSI
                     VIPPK"
     gene            81261..>82072
                     /locus_tag="LP386_000292"
     CDS             81261..>82072
                     /locus_tag="LP386_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HBL1917563.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETRIVDAKKGKIKYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FDRWREEQENSFQDWREGQESDYLSWFESIKDILKSIDPGGVMLAELMDARVDLQGVR
                     HESISERFLSDLNYLYQKMKAALFTIEYGEIEVTDILQDDLFSDNHEVEKIET"
BASE COUNT        27793 a        13459 c        17144 g        23676 t
ORIGIN      
        1 ggcacgtcag tcacgatatc aaacaaaaag tatacaccct tcttcattct agttttcgca
       61 gcaggaattt tgaaatagtt cttattagaa tagtagagat tgattaataa gctatcttcg
      121 attgctaaaa agaaaacttc tgaatcccac accttataaa aatctttgac aaatctattc
      181 gaaggatcga atttaaacca taattgtgtt tttccttcca ttaacatata aagttcacct
      241 caaaaagagt atacgaacaa atgtttgtat tgtaaataga aaaagatgag ctaaattaaa
      301 tgcccatctt ctttgataga tattataaat ctaataattc ttgtttcttt ttattaaatt
      361 cttcttctgt aatgattcca tcatccaata gttctttata ttttcttatt tctgaagctg
      421 aggaaattgt tgatgtattg gaatttgtag cagaaatatt tcttcttttt aaattataaa
      481 taatttcgtt taaagaatca cttatcctat caacagtatc tttatcaact gcaacattca
      541 atactttacc aagagtatca atagttaatg tacccaacag cactcctctt tttttactaa
      601 tattatttaa attgtctaat ataatacttt gtacattatt gcctatcatt ttttgttgag
      661 ctacaattaa acgtttatta gttaatgcgt atgcataatt attgtcatgc ttagttgatg
      721 agatataatt atgcaatcct acaaagcaga agattacgta ttcgtcactg ttaagttgat
      781 ctgatattaa gttaaaatga tgagttgtcc attttttagt cattccttta ccgtagccgt
      841 atttaagaca aaattctacc atctcttcag tggttctcat tctatcatta cctatatcat
      901 gattgttttg tgcagtatga tcagatatgt ttaattttct tttttctgat ggatccttat
      961 ctaaatcttc taaattcaaa gatcttatta ttttataagg agtagtcata ccgtaaccag
     1021 cttttttcat acaattgccg caaacaattt gtttatcttt gattttatat gaagttaagc
     1081 caattttacc tccgcacttt gcacattgtt tactcacatt agttcctcct agatatcagc
     1141 tttctactac tattaacatt ctatcaatag tgaccatact ttgaccatac tttttagaaa
     1201 gaatagaaaa ttccaagata tttaataata gaagaaaagc actaacatca tgggttcaga
     1261 agaattgaga gcttatcagg aaacagtata attgaagtgt ctgtttatcc agtagctcaa
     1321 gaagcttaat tgaatcttat gattaaagag gttgtgacaa gacttttgtc acagcctttt
     1381 ttgtttataa aaataaaagt tgtagtggag gctacgaagt ttactttgtc tttttacact
     1441 taatattttt ttgccaattt ggaatcagga tgttttgata actatcgttt tcaattgatg
     1501 gaagctatat tgtttgctat cagtgaaata attatatggt aaacagtgtt ctttttcttg
     1561 tttccattat aaaaatcgta tcgggatttt tcgttctttt aaattgaaca tttctatcta
     1621 tccgcgtgtt atcaacaaaa caaaatcagg taaatagttg acgaaacaga aataaataca
     1681 tagtattatg ttttgaagcc taagtacaat agtctataga aaaggagcga taccattggc
     1741 aaaacgcatt gaccgaattt atatgtatgt caaagaaaaa accgctcatt taacaaaggc
     1801 agaatatgat caaggagtaa caacacagga aattgctgaa gtgttaggga ttcagcgaac
     1861 aaatagcagt aaagatctga atcagctagt gcgcgaagga aaactgataa agacagacgg
     1921 acgaccagta cgttacatat atcaaacact cgttacgcac gtaaagccag ttacaaaaca
     1981 tgtagtcagt tacaaagaaa cgccggtctc tgaagaaaaa aatacactcc aaatagatac
     2041 taaggatatc tttgcaaaaa tcattggagc taacggcagc atgaaaaatt cagtggaaca
     2101 ggcaaaagct gcgattttgt atccgccaag aggattaaat tgtttgatta caggacctac
     2161 cggatcagga aagacttatt ttgcacacgc gatgtatcat tttgcaaaag cgcatcatgt
     2221 aatagatgag gaaacggaac tgattgtttt caattgtgct gattatgcca ataaccctga
     2281 gcttttgatg agtcatttat ttgggtacgc aaaaggtgct tttacaggcg cagatgaaga
     2341 aaaaatgggg attatcgatc aagcggatgg cggtatgctg tttttggatg agattcaccg
     2401 gttgccgcct gaaggtcaag aaatgatctt ttactttatg gatcatggaa cttacagtcg
     2461 tcttggggaa acaacgaaat cccatgaagc aaatgtacgg atcgtaggtg cgaccacaga
     2521 agacccaggt tcttctctat tagaaacttt tgttcggcgt atcccaatca atatcaaact
     2581 tccggctttt gaaaaacgtc ctgcaaatga gaaagtcgat ttagtaaaaa tcatgattgc
     2641 ccacgaagca aaccgcacgc agcgaaagat ttctttgaca gaagatgtag caaaagcatt
     2701 gatcggcagt gtgacctatg gaaatatagg acaattgaag tcaaatatcc agttagtatg
     2761 tgcacgagga tttctaaatc atatgcaatc acccgaaatc tcgatcacaa tcgatgattt
     2821 gacagaaggg attcgtagcg gattgattca attagcaagc aaccgcagtg caatggcaga
     2881 gctttctaaa atattggagc caaagataac tgtagcacca aatgatacga tcatgaaaat
     2941 ccaatcggac tcctatgagt taccttataa tctatatgat atcatcggag ataaagcagc
     3001 tttactgaag tcggatggtt tggatcaaga agcaatcaat catttcattt ctacagatat
     3061 caacatccat ctgaagtctt tctataaaga ccatggtttt tcttttaatg cagacagcaa
     3121 attagcagaa tttgtagatc cgaaaatcat agaagtgacc aatcagattt atgtaatggt
     3181 caaaagatct ttaccatatg agtttcagca aaactttatt tatgctatga gcttgcatat
     3241 cagttctttt ttgaaaaaaa tcaacttagg agaagaacgg catacgaatg ataacatccg
     3301 tgagatggct tttgattttc cagatgaata tgctgttgcg aaagaagtgc gtagttatat
     3361 cgaaacgtat tttcaagtgg agattccaga aagtgaagac tattacttga ccgttctact
     3421 cgtctcgtta cgggcaaatc aagcaagcgg cagaatcggt gtagtcgttg cagctcacgg
     3481 aaacagcaca gcaagcagta tggtccaagt tgtccaacag ttgttagatg cagagaacgt
     3541 acgagcagta gacatgcctt tggatatgga tccgaaaaca gcattggacc gaattgaacg
     3601 caatgtacaa gaagtagatg aaggaagcgg ggtcatactc ttagtagata tggggtccct
     3661 tgcgtcgttt aattcgcaaa ttcaaagaga cactggaatt ccagtacgta ctgttgatat
     3721 ggtaacaact tctctagttt tggaaactgt acgaaaggtc tcagtattag ggacagatct
     3781 agatatgttg catgaatcat tgaaaaattt tcgaggttac gcagaaatat cttctgtaga
     3841 atctgttcag gaagcaaaac ctattcataa gaaaaaagct gttttggcta tctgcgcatc
     3901 tggcgaaggt acagcacaaa gaatcaaaga attgatcgaa cgagcggtaa acaagcgtca
     3961 agaaacagaa ttagaagttc tagctttgtc gattgtggaa gtgaaagaag aactgccagt
     4021 tatccaaaaa gaatatcaga tcatagctac tactgggatt actgatttga atatccaagc
     4081 cccatttatt cctttagaac gttttattga tcaaaatatc gaagtcattt tggatcagtt
     4141 gctgatggaa tcagaattgg aggaaactga attcatctcc ctagatgaag agtcagctaa
     4201 aaatacgtgt gttgagttta tctctgataa cttcatcttt attaatggta gtaagttaat
     4261 cgatccaatg tggcaatttt ctacacaaat ctctcagacg acgggaatcg gcgatgaaga
     4321 atatggattc aaaatcaacc tagtgatgca cacagcagga atgatcgaac gtattattcg
     4381 gaatgaacca ttgactgtgg aagaaaacga attgacaaat acaacgaatg atcctcttta
     4441 tagccaattg gcagcctcag ttgttctgtt ggaagatcag ataaaagtaa aagtgccgat
     4501 agaagaaatg tattatctgc tacgtctagt ccataatcag ttagataaaa aagaatacac
     4561 tgtgccatga atacacaaaa acgatacact tttatagtgt atcgtttttg tgtattggtt
     4621 aagaatcctt taaattcaat tagtgtatcg taaaaaagtt ggcacgcttt ttgcttatag
     4681 tagtgtgtgc taggaggtgg ttgttcacac agaaatgata ggggtttctg tgaagtagtg
     4741 aggaagaagg agttttgcag atggatattc gattggcacg tatagatgat cgtttaatcc
     4801 acgggcaagt cgcaacagtt tggtcgaagc aaacaggtgt tgaacgtatc attgtgatca
     4861 gcgatgtagt cgctcaagat aaattgagaa agtttctact aaaagaagct gcaccgccgg
     4921 ggatcacagc aaatgtaata accgtgcaga aaatgattca aatctatcat agtggattat
     4981 tatcacgagc aaaagtgatg cttttattca ccaatcccca agatgttgaa gcggttgtcc
     5041 gctgcggtgt acagttgaag tcgttgaata tcggcggtat gagttttact gaaggcaaat
     5101 caatgattac caattttgtt tcagtaaatc aacaagatat tgattccttt cgttacttga
     5161 acagtcaaga agtggagtta gagattcgaa aagtacctgc tgacaggaaa atccttttga
     5221 tggaactact agcgaaaatc aaaaaggtgt agcaagaatg gttgttggaa aaggtcaaat
     5281 aattctgttg taatggttag caattattaa tatttttgaa tttgttacaa caaaagtaaa
     5341 taggaggtat aaatatggta gggattatcc tagcaagtca tggacaattt gctgaaggaa
     5401 tcttacaatc cggttcaatg atctttggcg aacaagaaaa cgtcaaagcc gtgattttga
     5461 aaccaagtga aggtccagat gacttgagag ccaaattgga agaagcggtt gcttcttttg
     5521 ataatcaaga cgaagtgtta ttcttagttg atttatgggg cggaacaccg ttcaatcaat
     5581 caaacacatt attcgaagag cacaaagata aatgggcaat cgtcagcggt ttgaatttac
     5641 caatgttgat tgaagcctac gcatcacgct tttcaatgga atctgctcat gaaattgcag
     5701 cacacatcat tgaaacagca aaagacggtg taaaagtaaa accggaagaa ttagaaccgg
     5761 cagaagcacc gaaagcagca gttgaagacg cacaacctaa aggagcactt ccagaaggaa
     5821 ctgtggtcgg agacggaaaa atcaaatatg tattagcacg tgttgactca cgtctgttac
     5881 atggacaagt tgcgacagct tggacaaaag cagtgcaacc aaaccgtatt atcgttgttt
     5941 cagatgcagt atcaaaggat gatctgcgta agagactaat cgaacaagct gctcctccag
     6001 gtgtaaaagc aaatgttatt cctattagca aaatgatcga agtagcaaaa gaccctcgtt
     6061 ttggaaatac caaagcattg cttttatttg aaaatcctga agacgtattg acagctgttg
     6121 aaggtggcgt agacatcaaa gaattaaatg ttgggtcaat ggcgcattcg gtcggtaaag
     6181 tcgttgtaag taaagtattg tctatgggac aagaagacgt tgaagcgttt gagaagcttg
     6241 aacaaaaagg tgtgaaattc gatgtacgta aagtacctaa tgattcacgc gataacatgg
     6301 atgatatttt gaaaaaagca aaagctgaat tagcaaaagc gtaataaata atattaaaat
     6361 ttataggagg cttatcatgt ctattatttc aataatttta gtcgtattag ttgcctttct
     6421 agctggtatg gaaggtattc ttgatgaatt tcaatttcat caaccactag tggcatgtac
     6481 attgatcggt ttagttaccg gtaacctcga agctggtatc gtacttggcg gtacgcttca
     6541 gatgatcgct ttaggttggg caaatatcgg tgccgctgta gcaccagatg ctgcattagc
     6601 atcagtagca tcagcaatta ttttagtttt aggtggacaa ggtgttaaag gtgttccttc
     6661 tgcgatcgcg attgccgttc ctttggctgt tgcagggttg ttcttaacaa tgatcgtacg
     6721 tacaatcgct gttccaatcg ttcatttgat ggatgcggct gctgaagaag gaaacatccg
     6781 taaggttgaa atgtggcaca tcattgctgt atgtttacaa ggggttcgta tcgcggtccc
     6841 agcagcagcg ttgctattta tcccagcaca aactgtgcaa tcattccttg aatcaatgcc
     6901 agcatggtta acagatggta tggctatcgg tgggggaatg gtcgtagctg taggttacgc
     6961 tttggtaatc aacatgatgg ctacaaaaga agtatggcca ttcttcgtta ttggtttcgt
     7021 tgtagctgca atttctcaat taacattgat tgctctaggt gctttaggtg ttgcattagc
     7081 tcttatttac ttgaaccttt ctaaaatggg tggttcatca aataatggag gcggaagcaa
     7141 ctctggtgac cctttaggcg acattttgaa tgactattaa tcttgaagga ggaaaataaa
     7201 atggcagaag aaaaaatcaa attatcaaaa aaagatcgtt tagctgttgc gtggcgctct
     7261 accttcattc aaggttcatg gaactacgaa cgtatgcaaa acggtggctg ggcattttct
     7321 atgattccag caatcaaaaa attatacaaa acaaaagaag aacgttctgc agcattaaaa
     7381 cgtcacttgg aattctttaa tacacaccca tacattgctt ctccaatttt aggggttaca
     7441 ttggctctgg aagaagaacg tgcgaatggc gcgcctgttg atgatgtagc gattcaaggg
     7501 gttaaagtag gtatgatggg tcctttagct ggtgttggtg acccagtgtt ctggtttaca
     7561 gtacgtccaa tgctaggtgc actaggtgct tcattagcta tgggaggaaa tatccttgga
     7621 ccaatcatct tcttcttagg ttggaacatt attcgttggg cattcatgtg gtatacacaa
     7681 gaatttggct acaaagctgg ttctaaaatt actgatgacc tttctggcgg attgttacaa
     7741 gacgtaacaa aaggtgcttc aattttaggg atgttcgtat tagctgccct tgtacaaaga
     7801 tgggtatcaa tcaaattctt accagttgta tcaactgtaa aattagataa aggtgcttac
     7861 atcgaatggg ataaattgcc ttcaggtggt gaaggaatca agagtgcatt tgaacaagtt
     7921 aataatggct tagccctttc tcctgaaaag gtaacaacat tacaagacaa cttagaccaa
     7981 ttgattcctg gtttagctgc attaggatta acattgttat gtatgtggtt gcttaagaaa
     8041 aaggtttctc caatcgttat catccttggt ttattcgtag tcggtgttgt tggacacgtc
     8101 atcggacttt tataatccat aaaaatatag ctcgggcgtt gtcccgagct ttttttatat
     8161 agtatactgt tcataaacaa atatctggag ggagaaaatg gttcaatcaa tcaatacaaa
     8221 agtagacttg gtaattgatg ctacttcgtt tacgggtctg acagattacg ggcaaatcat
     8281 gataggtgat aatggttttg agttttacca tgcgcgagat agacgcaaat atatccaaat
     8341 tccatgggaa gaagtggatt atgtactagc atcagtcatg ctaaagggaa aatggattcc
     8401 tcgatatgcc attcaaacga aaaaaaatgg tacatacaca ttttcttcca aagaacctaa
     8461 aaaagtgctt cgtgcgatca gagaatatgt agatgaagat agaatggtac aatcattgag
     8521 tttctttgat gtagtgaaac gtggtattcg tagtatgttt aaacgcaagt aaaaaataaa
     8581 gaaaacttct aagaggaggt tttctttatt tttttacttt gcagaagaaa atatgaaata
     8641 gcaaaaccaa ttatttgtcc cctttaaatc ccatatgcta aaattgatta gcaaagaagg
     8701 aggttatatt atgagttggt tatggacatt gattgttgga gccgtgatcg gagcaattgc
     8761 aggtgcgatc accagtaaag gaaattcgat gggctgtgta acgaatatca ttgctggact
     8821 agtcggttca agtattggac aagcgatttt cggcgaatgg ggaccaaaag ctgcaggtat
     8881 ggcacttatt ccatctattt taggcgcagt gattttggta gcagttgtct catttttctt
     8941 tggaaaacga tcataagttt ttacaaaata gtaaactaaa aggagttgca gcgagactgt
     9001 gactcctttt tggctttatt tatttaaaat aaaaagaagt tttccggaaa tttttattta
     9061 actgtcgtgt acgaagaaaa gtttgctata atggaaaaaa gcgtgcaaag aaagagggag
     9121 tttcattatg atgctacgtg tagaaaaatt gcgcaaaaaa atgcaagaag aaaatttgga
     9181 ttcatttttg gttaccagtc cgtacaatct tcgttactta acgaacttta caggtacgac
     9241 aggattagct gttattactt tggaaaaagc attttttatt actgattttc gttataccga
     9301 gcaggcggca gcgcaggctc aagggtttga aattattaaa aatgtcggac ctatttttga
     9361 tgaggtagca aacttagtac gcaaagaaga actgcactca ttagcttttg aggaaacaac
     9421 agtctcattt ttagaatatt cggttttaga agaaatcatc gatgcggaat tagtacctgt
     9481 ttcacagatg atcgaagaac tcagagaagt gaaagatgaa gaagaaatcg ctattatcga
     9541 aaaagcatgt catattgcgg atatggcata tgatcacatc ctgaaaatga tccaaccggg
     9601 catgactgag attgaagtcg caaatcaact agacttttat atgcgttctc ttggcgcttc
     9661 aggtgtttct tttgatacga tcgttgctag cggattgcgt tcggctatgc cgcatggtgt
     9721 agcaagcaaa aaaatcatcg aacaaggtga cttgatcaca ttggactttg gttgctatta
     9781 cgaagggtac gtttccgata tgacacgtac attcgctatt ggtgatcctg gggaaaaatt
     9841 aaaagaaatt tatcaaatag tcttagatgc tcaattagca gttattgatg ctgcaaaacc
     9901 aggaatgact ggtgtccaat tagatgcagt tgctagagat tatatttcaa aacatggtta
     9961 cggggaagca tttggacatt ctacaggaca tgggatcggt ttagagatcc acgaaggacc
    10021 aaacgtttct tctcgtgcag aaaagcaatt tgtaccagga aatgtgatca ctgatgaacc
    10081 agggatctac ttaccaggaa tcggtggagt acgtattgag gatgacttgt tgatcacaga
    10141 agatggaaat cgtgtgttga ctcgttcacc aaaagaattg atcatcttat agtttcatca
    10201 atagaagaag taagcgtaaa aatcagtgtt cacagacttt gttatagaaa atcactcgat
    10261 ttaatgatac actatagaag aacttttaag ctgtaagaga taataaagtt gggtgttttc
    10321 tccaattcat agcagtttgc agctgatcgg cggcagtttt cttaccacgt gatcactatg
    10381 ccgcatcata gagaattcgg atgtatctcg tgcttaggca aagggaggaa taaataaatg
    10441 gcagatgaaa aaaatttgat tttaaacgca aaccaagatt taggagagat cgtgatcgct
    10501 cctgaagtca tcgaagtaat tatcgggatt gcagcttcta aagtagaagg cgtatacgga
    10561 atgcgcggaa cttttgccag caatgtcact gaattattag gacgtgcagc tcacggaaaa
    10621 ggtgtttact tagcaaacga ggaagatggc ttgaaagtag atctttactg ttatctagaa
    10681 tatggtgttt cagttcctaa agtagcaatg gaaatgcagg aacgggtcag ccagcaagtc
    10741 cttttcatga cggatatcga tttatctgaa gtcaatatcc atgtagtagc tgttgttcct
    10801 gaaaaattag aacaaccaac aatcgaagaa ctttttgaag acgaagagga agagaatgaa
    10861 taaagaatta tcaagacacg agattcggga aatggcattg caggctttat ttccattaga
    10921 cttcaatgca gacctaacaa aagaagatgc gattttcaac gcaatcgaat tagaccaccg
    10981 cgacatgatc aacgaagatg aatcagagtt tgttcctgtt tatcttgata cgctagttgg
    11041 cggtgtctgt gcaaaaaaag atgaattgga taaagtgatt gaaaaacatt taaaaaacaa
    11101 ttggcacatc aatcggatct caaaaatgga tttggtgatc ttgcgtatcg cgatttttga
    11161 aatgacttat gtgacagatg taccagcggc tgttgcttta aatgaagcaa tcgagttggc
    11221 aaaaacattt agtgatgacc gttcacgtaa attcgtcaac ggtgttttat ccaatgtatt
    11281 gaaagaatta gaagctgggg cgtaagtcct agcttttttc tatgaatcat cataaacctg
    11341 ttataaatcg ggaaaattct atggtagaat gaaaacacaa aaaatatctg ggagtggtta
    11401 gatggcagaa ttgattaacg gaaaagaatt agctgaaaaa atgcaggcag agattgctga
    11461 aaaaatccaa aaattgaaag ataatggtat ccatcccgga ttagtcgttt tattggtagg
    11521 ggaaaatcca gccagccaaa tctatgtaag aaataaagaa cgtgtagcaa aagaaatcgg
    11581 aatccattca ttggtagagc gttatcctga gacgatttct gaagacgaac tacttgcaga
    11641 aattgaaaaa tacaatcaag atcctagttt tcatggtata ttggtccaat tatcattgcc
    11701 aaagcatata gatgaagaaa agatcctgtt agctatccgc cctgaaaaag acgtagacgg
    11761 ttttcatccg atgaatttag gcagactcct tgcgggtaaa ccggacaaga ttccttgtac
    11821 tccatacggc atcatgaaaa tgtttgaagc ttattctatc gatccggcgg gtaaacgagc
    11881 agtagttatc ggacgaagca atatcgtcgg taaaccgatg gctcagctac tcttgatggc
    11941 agatgcaact gttactgttg ctcattctaa aaccgaaaat ctggctgaac tggcacaaga
    12001 agcagatatt ttagtcgtag caataggacg tggacatttt gtcacaaaag aattcgtaaa
    12061 accaggtgct gtagtgatag atgtagggat gaatcgtgat gctaacggta agctgatcgg
    12121 tgatgtgaaa tttgatgaag tggagcctat tgcaggctgg atcactcctg tgccaaaggg
    12181 tgtagggcca atgactatca cgatgctgat gtatcaaacc gtaaaatctg ccgaagcttt
    12241 tggagcaggt gaatagatgg cacaagaata tttaactgtc actacattaa cgaagtattt
    12301 gaaaagaaaa tttgatgccg atccttattt agaacgcgta tatttaacag gcgaaatatc
    12361 gaatttccgt ttacgtgcca atgcccatca atatttcagc ttaaaagatg accatgcaaa
    12421 aatatctgct attatgttca aaggagcatt ccaaaaatta cgattccagc caaaagaagg
    12481 aatgaaagtc cttgtcgttg ggcgtatttc attatatgaa gcgggaggtt cttatcaaat
    12541 ctatgtagag cacatggagc ctgatggaat aggtgcttta tatcaagaat tggaagaacg
    12601 aaaagaaaag ctgatgaagg aaggcctttt tcaagggcct aaaaaaatgc tgccacgttt
    12661 cccaaagcga atcgcggtcc ttaccagtcc aagcggagcg gttatccgcg atatcatcac
    12721 gacggtgaaa agaagatatc caattgtcca attggttttg ttcccaacag ttgtacaagg
    12781 aaaccaagca gcggacaatg ttgtcaggaa tatccagaga gtagaagaga tgggcaattt
    12841 cgatacaatg atcatcggtc gtgggggtgg ttcgattgag gatttatggc cgtttaatga
    12901 agagcgggtt gctcgggcga tttatcaagc taatacgccg gtgatttcat ctgtaggaca
    12961 tgaaacagat accacgatcg ctgatttagt agcagatgtt cgggctgcca ctccaacagc
    13021 agctgcagaa ttagctgttc ctgttttgtc agaagagttg atgcgcattc aagaacggca
    13081 agctagattg cagcaggcgt ttgtacgcca gatccagcgc aaacaagaac ggttcgagcg
    13141 tgctcgacgt tcctatgtat ttcggcagcc tgaaagattg tatgaaggtc agaccatcaa
    13201 attagaccag ttgaaacagc gattatatca agctacacag caaatttatc atgcgaaaga
    13261 aaaacaaacg atcgcattaa gccaccaatt ggaacaagtg gctccgcttt atcgagttaa
    13321 agcagctcgc caagaaactg cttatctaga aaaacgctta gaagagaaaa tccaacaata
    13381 tatgaaacaa cagcagcagc gttttgctca agctgttcaa tctcttgatt tgttgagtcc
    13441 attgaaaatc atgggaagag gctacagcta tacgacgtta aatgatcaag tagtaaaaag
    13501 tgtcaccgag attcatcaag gggatttgct gacgatccat tatcaagatg gaatcgttaa
    13561 aggacaagta caagagatag acaaaggaga ataaaaatat ggaaaatcca acttttgaag
    13621 agtcactgca agaattagaa aaaattgtca tgcagttaga acaaggagac gttccattag
    13681 aatcagctct agattcgttt aaacgaggaa tggaattaag caaacattgc caagatacat
    13741 tagctaaagc agaagagacc ttgacgaaaa tgatgacaga atcaaatgaa gaagttgatt
    13801 ttgacggaaa cgaggaaagc tgagatgaga ttaactgact tttcagctat tcatctacct
    13861 gctgtagaaa aagaaatctt gtctttttta gatgagcata caacggatag aggactctat
    13921 gatgcgatga gttattcagt gaaagcaggc gggaaaagaa tacgtccctt attactttta
    13981 acggccgttg cttcctttga tgagcctatt gatgttcccg tctatcaagt agcagctgct
    14041 ttagaaatgg tgcatacgta ttccttgatc cacgatgatt tgcctgcgat ggacaatgat
    14101 gatcttcgta gaggaaaacc taccaatcat aaagtattcg gcgaagcatt agctatattg
    14161 gccggagatg gtttgcttac aggagcattc cagctaatca gtatggcaca cttaggtaat
    14221 tctcctaagc ttctgctgct tcagcaatta gctgtttgtg cgggatcaca aggtatggtt
    14281 gctgggcaag ctgcagatat cgagggcgaa tcgaaaaagc tttctttaga agaattagca
    14341 tttattcatg aaagaaagac agggcatttg attcgttatg ccttgctggc tggtggcata
    14401 ttagcgaagc aacctgaaga aatcttattg ctacttcaac gattagccga acatttaggt
    14461 ttagcttttc agataagaga tgatctactc gatgtgattg gtacaacgaa aacattaggg
    14521 aaaacagctg gtaaagatga acgtatggaa aaaaatactt acccgcgttt attaggccta
    14581 gaaaagacac gtgaggcgtt ggagattgag ctgttatccg ccaacaagat catagacaaa
    14641 ttagaagagg acgttttttc ttttgatggc gggctgatgc gccagatgat caagcaattt
    14701 gatgtggaga aatgagggaa agaatggaaa aagaacgcgt agatgtatta gcggtcaaac
    14761 aaggattatt tgaaacaaga gaacaagcca aacgttcagt gatggctggt ttgatttaca
    14821 acgaaaaaaa cgagcggttt gataaaccgg gagaaaaaat tccagtgagt agtgaattaa
    14881 gagtcaaagg taaaaaactt ccttatgttt ctcgaggggg attaaaatta gaaaaagcac
    14941 tcaaagcatt tgatctatct gttgaaggaa aaacattgtt agatattggt gcatccactg
    15001 gcggatttac tgatgcagct ttgcaaaatg gcgcaaaaat gagttatgct ttagacgttg
    15061 gctacaatca gctagcttgg aaaataagac aagatcctag agtcgtcgta atggaaagag
    15121 tgaattttcg ttatgcaaaa cccgaagact ttaccttagg aattccagaa gttgctgtta
    15181 tcgatgtttc ttttatttca ctaaaactga tgctgcctcc attacatgct attttaaaag
    15241 aagagggaga agtgattgct ttaatcaaac cccaattcga agcaggcaga gaagctgtag
    15301 ggaaaaacgg aattgttcgt gaccctcaga cccatcaaaa agttttagaa gacattttgt
    15361 catttgcggc acaaggtgga tatgatgtgc tggaattaag ttattctccg atcacggggg
    15421 gagaaggaaa tatcgagttc ttggctcact tgaggaaagt acccgaaagc ggaacaatca
    15481 attcagctat taatatggca gaagtggttt caaatgcaca cgaacagttt gaccataaat
    15541 aaattgtaac tgtgaaaatc aagtgagaag tatgcggatt cttctttatt ataccaagga
    15601 aataagctat cattgattaa gaagaatatg ctaaggagcg aagacgtaat gagaaaaaaa
    15661 gatcggcatc gtttgattac tcgattgttg agtgagcaag atatccgaaa gcaggaagaa
    15721 tttgttgaaa tcctgaaaag caaaggaata tctgttactc aagctacgat ttccagagat
    15781 ataaaggaac tgaaactgat caaggtaccg gcttcagatg gcggctaccg ttatagcata
    15841 ccagctgaaa caaacgaaga tgtaaatact aaattggaaa aactattaaa agacgctttc
    15901 gtggcagttg accaaatgga aaaatttgtt attttgaaaa cattgccggg aaatgcttcg
    15961 gcagcagcaa atttgattga taaacgttac aagaaagaat tattttcgat tatcaatgat
    16021 gacgataatg ttttgatgat tacacgaact gaagaccagg cagttttatt gaagaaagac
    16081 ttcctgcatt acctttaagt tgaggagcga atgtgatgct acaagaaatc agtattacta
    16141 actttgcgat tattccggaa ttgcggcttt cttttcacga aggaatgacc gcgctgaccg
    16201 gagagactgg tgcgggtaaa tccattatta tcgatgcttt aggtctgtta gcaggaggaa
    16261 gaggttcaag cgattatata cgtcaaggag cagaaaaatg tgtgcttgaa gggttgtttg
    16321 aactaccaaa acaagaagga ttctctgaac tgatggttga attagggatc gaaacagatg
    16381 aggacaatct gattgttcga cgggatatgt ccttaactgg aaaaaatgtt tgtcgagtga
    16441 atggtcatat tatcacatta gctaatctga gaagaatcgg cagttattta gtagatatcc
    16501 aaggacaaaa cgaacatcag gaactgctcc agcctgaatc acatcttgct ttattggatc
    16561 gttttggaga tgtagctttc caacagaaga aaaagagtta tcagcaagaa tatatctctt
    16621 atcgtgagct ggaaaaaagg gtacgaaaag tgcagcaaaa tgaaaaatcc tatgttcaga
    16681 gaatagatat gctccatttc cagcaagaag aaatagctgc tgctgatttg caagtcggag
    16741 aagaagagaa attaaaagaa gaaagagaaa aacttagcaa ttatcaaaaa attgctgatg
    16801 gattagctgc aggttacgga gcactgacga ataatgaaca aaacagtgta gatggtgttg
    16861 gcttggccgt ttcagaactg caagggatcg cccatctaga tgtggagtat gaagcaattt
    16921 atgaaaatat ccaaagtgct tactatttgc tgcaagatgc aatcggcgat atgagtcgtc
    16981 agattgattt attggagtta gatgagagtc gtttagaaga agttacgcaa cgtttagaat
    17041 taatccgaca gttgaaacgt aaatacggcg aatccattga gtcaatattg gcttactatg
    17101 acgaaatcac cgaagagcta gcttcttctg atttttcaga aggtcaattg gacaaaatga
    17161 aagaggaact agagcaaaaa gagcttctac ttcagcaaca agccgcagat cttcatgaag
    17221 cgcgtaaaaa aatcgcaaaa gaattggaaa aatccattct gcatgaattg aaaagtctgt
    17281 atatggaaaa cactgagttt gaggtacgtt tcttaaaaga agaaaataga caattgaatc
    17341 atgatggatt tgaccaaatc gaattttaca ttacgaccaa tccaggagag ccactgaagc
    17401 ctttggtgaa agtcgcttct ggtggcgaac tgtctcggat gttgcttgct ttgaaaacta
    17461 ttttttcttc tgagcaaggt gtgacaagta ttatttttga tgaagtggat acaggtgtga
    17521 gcggaagagt tgcacaggcc atcgcagata aaatttctca aatatcgaaa tactctcaag
    17581 ttttgtgcat cactcatctg cctcaagttg ctgcagtcgc cgactatcaa tattatattg
    17641 tgaaagcagt gattgatgga cgtacgcaaa cttctgtttc agagttgaaa acaaaagaaa
    17701 gagaagaaga aattgcacgt atgctggctg gaagtgagat tacaaaactc acactcgaac
    17761 atgcaaaaga actattgaaa ctcgcaaaaa ggacctgagc cacctcgcag tggttcaggt
    17821 ccttttcagc agctgatagc tatattttat ttttacatga cactcattac agcagtcaat
    17881 acaacagatc caatcgttaa aatcagcatt gtccaaatga caaattttgt tactttagca
    17941 aaagtacttg tttgtttttt ttcacgcatt gttttcaacc tcgtcattaa ttagttgatt
    18001 caagtgtaca atcttttttc catttccaca agagggcttt tttataaaaa cttccctttt
    18061 tttaaataat aggtagttac gatacaaata aataatgtta atagaactag ccatataaag
    18121 gcatcatccc tttcagcaat aggtaactta atgttcattc catagatact gccgacgatt
    18181 gtcggtatag ttaaaataat cgttaaagaa gttaaaattt tcataatatt attcagatta
    18241 ttcgatacga ttgctgaaaa agtctgattc atttgttcta ctagttttaa ttgaatgcga
    18301 gaagtagtca ttgcctgctc tgtttccacc aatacatcac gtaaatgatt tttcaaagca
    18361 tgattttctt ggaaaagttt attttgcgct agttctttca atgcatctaa attagcagaa
    18421 gtcgcttctc tgaaataaac gaggcttttt tggatatcca tgatttgata aagttgtttg
    18481 ttttcagtgg atacttgaag tttggcttcc aaagtatcgc attgagattg aagcgtagct
    18541 aaataactgt tgtaagagag tgtgacctgc caaatgaatt gaaagaagat attgagatta
    18601 ggcgaaatat cactttttgg aaaggtctgg ctaaagactt tctttaaaaa cagtggttca
    18661 tgattcgtaa ttgtgataag cttctttttg ggcgtcaaaa taatagagag cgggtatgta
    18721 tccacttgaa aataaccgct aggacttgtt ttagcaaaag gatattgtaa caataataac
    18781 gctggctttg tcaactttga ttgattgaat tcttctgtac gggaattttc tgcatcgtcc
    18841 aatatggaag tgatgtaatc tgacggaatt tcaaattgat gtgtcagctg atgaatctct
    18901 tcttgattag gacgttctac acaataccag atcgtttggt cagtttcctt tccggtatta
    18961 cgcagtttct cattatctaa tgtaaaatat ttgatcatga ttttcctcct gttgcctgtt
    19021 tcttttatta taacggatag ggaattggaa tacatggaat gtgtttgtaa gatatagaat
    19081 ataactgcat aaatttaaat aaaatgaaac agttgtgtaa agtatataca gtatacttga
    19141 agcaacgata aaaaaggagt ttacgttcat gggcacattc acaccactta tcttgttttg
    19201 gtatatttac ccggtaatcg ttttgtttgg ttgccaattt cttgtaaaat tattttcgtt
    19261 aaatcgtcgt tttaaaataa aagcccctga tttggcgatt ccttttttgt ggggcggtat
    19321 gcatgcattg tctagaaata cagggacaat ttctatctta ccgtttttct ttatttctgt
    19381 tttgctaatg ggaatttgta ttgctgtttt ccaagcatat tattatgaag aaattattta
    19441 tccgcgttat ttcaagatga cttggcgttt ggtttttctg ttgacaatcg tcttgtacgc
    19501 tgtcttgatc attgtgaaca tactttctta cctatgaaaa aaatagaaaa gctgtaaaaa
    19561 gtcttttaaa aggctttttg cagcttgatt tttaaaaaaa tgtttatgaa taaaaaaagt
    19621 tgttcccgga tttcccagaa aaggtggtag aaagtggggg attgtggtag actaatttta
    19681 gttagtggag gaatgggggg ctttcaatgt tgatgggtga attccaacat aatattgatg
    19741 caaaaggacg tttaatcgtg ccctcaaaac ttcgtgaaga acttggcgaa aagtttgttc
    19801 tgacacgcgg attggatggc tgtcttttcg gctatccgat gagcgaatgg gaaaatctgg
    19861 aagctaaact gaacgaaatg ccgttggcta aaaaagacgc acgtactttt gtgcgattct
    19921 tctattcggc tgccactgaa tgcgaacttg ataaacaagg acgaatcaat atacccagca
    19981 cgttaagaaa ttatgcagct ttgacaaaag gttgcgtagt catcggtgta tctaaccgaa
    20041 ttgaaatttg ggatgagaca cgatggcaag atttttctgc agcagcagaa gagaactttg
    20101 acgaaattgc tgaaagtatg attgatttcg gactataaga ataggaagag gctgactaat
    20161 gactgaaaca tttcaacact atacagtcat gttgaaagaa acggtagatg gattgaacat
    20221 caaaccggat ggcgtttatg tagactgtac actcggcggt gccggacata gtgaatattt
    20281 attaagccaa ctaagttcta aagggcatct gtatgcgttt gaccaagatc aaaaagcaat
    20341 cgatcacgcc aagctgcgtt tagcttctta tgtcgaacaa ggtatggtca catttatcaa
    20401 agcgaacttc agagaattag aagaacgctt gagtgagcat gtagataagg tagacggcat
    20461 tttgtatgat ctaggggttt cctctcctca gctagatgaa gcagaacgtg gatttagtta
    20521 tcatcaagat gcaccgttgg atatgcgcat ggatcagtca gctcctttat ccgcttatca
    20581 cgtaattaat gaatattcct accatgaatt agtaaagatt ttcttccgct atggcgagga
    20641 gaaattttcc aaacaaattg ctcgtgaaat cgaacgagta cgaaaaacaa aaccaatcca
    20701 aacaactggt gagcttgtcg aaatcattaa acaagtcatc ccagctcccg caagaagaaa
    20761 aggcgggcat cctgcaaaaa gaatttttca agctgtgcgg attgcagtaa atgacgaact
    20821 cggtgccgaa gaggcctctt tagaacaggc aatccggtta ttgaaagtca atggaagaat
    20881 cagcgtaatc acattccatt cattggaaga cagaattgtc aaaagtatgt ttaaagaata
    20941 tagtacggta caagatctac caccgggact tcctgtcata cctgacgaat tccaaccaga
    21001 actgaaagtc attactcgta aaccaatcct tccttcagag gaagagctaa cagaaaacaa
    21061 tcgatcacgc agtgcaaagt tacgtattgc agaaaaaata agaatgaaag aggagtagaa
    21121 tgatggcaga attaaagaaa atgcaagatt acgaatatga tttacctgaa ttggtggatc
    21181 agccggaaca acaaatgcct gattcttctt cgaatcaaga aatcattctt ccacaatcac
    21241 cggcaaaacg attaaagcag atttctgctt tggaaaaaat tgctgtggca agcgtggcga
    21301 ttgctattgt tgctttatgt gttttaacag ttatgctgcg cacaaatatc agcggagctg
    21361 aaaaagaaat cacgtcaata caaacagaaa tcaatgataa aaagcaagaa aaaacgagtt
    21421 tagaacaaga aaaaaacgaa ctttctcgta ctgaacggat taaacaaatc gcagaagaaa
    21481 aaggattgtc tattaatgac gacaatttaa ggaaagtgaa gtaaatgagt cttaaaaata
    21541 aaattcggcg gtttatggaa aagaaaaatc taaatccgat gaacaatcgc aaaaaagtag
    21601 gtatcatttt atttgctacg agtattggat tgttcttttt atttgccgtc cgtttctcgt
    21661 atatcgttat tggaggtcat gttgctggta cctcattagc tgaaaaaaca aaacagttgt
    21721 accaaggaag tgaagtagta aaagcaaaaa gaggaacgat ttatgatcgt aacggtgtgg
    21781 cgctcgcaga agatgcctcc tcttattcaa ttaaagcgat actctcaaaa acatatacct
    21841 ctggggataa aaaactgtat gttgaagaaa agaattttga taaaatagca gaaatcctgc
    21901 ataagaatct ttctatagac aaaaaagatg cactgaatat tttagaggac ggcgcaaaaa
    21961 aagagctgta tcaagttgaa tttggtagct atgggaaaaa tatctcccaa gaaaccaagc
    22021 aaaacatcga agcggacatg aaaaaagaag gtgtcgctgg tctttatttt gtcgaccatc
    22081 aggctcggat gtatccaaat ggcgtctttt cttctcattt tattggatac gcagttccag
    22141 acaaagatga gaatggctta gttggtaaac taggtttgga gtctgcttac aatgatatct
    22201 tgagcggtaa agatggtaag attatttatc aaaaagataa ttttcaaaat cctctgccag
    22261 gtacagtggc agaagaagaa aaagctgtcg acggacaaga tatctacacg actttagaca
    22321 gcagactaca aagttattta gaaacactga tggatcaagt aaatgaagaa tatcagccag
    22381 aagaattgac agcagtcctg atgaaagcaa aaaccggaga aatcttggca atgggacaac
    22441 gacctacttt caatcctgaa acaatggaag gattgactgg aaaagatgct atctggcgta
    22501 atttcttggt acaagatagt tatgaaccag gatcaaccat gaaagttttc actactgcag
    22561 ctgctatcga agaaggagaa ttcaacgaga atgaaacctt ccaatctgga aaaatccaag
    22621 tagaagatgc tacgatcaat gaccatgact ttggtgaaaa aggtgtgctg accatgcgtc
    22681 aagctctttc atggtcaagt aacgtcggga tggtcatact ggaacagcga ttaggcggac
    22741 gatggtataa ctatttacaa aaactgggat ttggacaaag tactcattct ggattagatg
    22801 atgaagtaaa cggtgcttta cctacattaa atattgtcga ccgagcaatg agtgcttatg
    22861 gacaagcggt aggtgtgacg aatttccaaa tgatgaaagc tttcacttct attgcgaata
    22921 acggtacaat gattcaacct cgatatatca gcaaagtggt ggatccccaa actggagaag
    22981 agcgaacaac tcaaacagaa gttctagggc aacctttttc aaaagaaaca acagaaaaag
    23041 tccgtgaata tatgagagat gttgtcgaaa gcgaaaacta cggtagtgct tatggtgtat
    23101 atagtgtacc tggatacaat gtatcggcaa aaaacggaac agcccaaatc gcttctgata
    23161 cagggggata tcaaacagga gatacagcct acctgtattc gattgtggag atggttcctt
    23221 ctgaagatcc agactatgtc ttgtatctaa caatgaaaca ccctaagaca tatgatcgaa
    23281 tggcattggc taaaatcgca aatccattga tgaaacgggc aatggatttt aaagaaactg
    23341 aagaagattc agatacagaa acaaaaacag aaaaagtatc cgtagccgat tatcgtaatc
    23401 ttgaagcgga cgttgcagca gctgatgctc aaaaaagtgg actgcaacct gtagtgatcg
    23461 gtaatggtaa aaaagtacaa aaacaatcta ctgccaacgg tgatcagttg atctctggag
    23521 aaaaactgat cctatatact ggtggtgata agctgatgcc tgacgtaaca ggatggtcaa
    23581 aagcagatat catgaagctg gggaaaatcc tcggtattga agttagtttt gatggagatg
    23641 gttattgtgt caaacaagaa cttgctccat atgaaaaaat cactgaagac aaacttagtt
    23701 ttactttaga agaataagaa gagaaatagg agagaaaaga gcatggaatg gacacaagca
    23761 ttgattccca ttgtcagcag ttgtgcaatg acaattgccg caatgccgct atttattggt
    23821 tattttcaaa tgaaaaagca aggtcaggcg attcgtgagg agggaccaaa gtggcacaat
    23881 agcaaagccg gaactcctac aatgggcggc ttagtgtttc tgatcggctc tattttgaca
    23941 ggaatttggg ttggagcttg gcaaaaacag ctaactccta ctcttttcat cttgcttttt
    24001 gtattagcgt tatacggagt aatcggcttt cttgatgatt ttataaaaat attcaagaaa
    24061 agaaacatgg gactgaactc gaagcagaaa ttgattggac agattctagg gggaatcatc
    24121 ttttatcttg tttaccgttc tgaaggttat ccaggtgtat tgaatttctt cggactagat
    24181 ctacctttag gaatcattta tggtattttc gctctcttct ggcttgttgg attttcaaat
    24241 gcagtaaatc tgacagatgg catcgatgga ttagttgctg gcttaggaag tatctctttt
    24301 gcagcttacg gtctaattgc ttggcatcag catcagtatg atgtattaat catttgctta
    24361 agtgttttag gaggtttact gggtttcttc gtctacaaca gaaaacctgc caagattttt
    24421 atgggagatg tcggttcatt agcgttgggc ggacttttag cggcaatttc tataatgcta
    24481 aaccaagaat ggacattgct tttgattggt ttgatctatg ttatggaaac agcaagtgtg
    24541 atgcttcaag ttacttcctt taagcttaca ggaaaacgaa tttttaaaat gtctccaatt
    24601 catcatcact ttgaaatgtg cggatggtcg gagtggaaga ttgatacagt tttttggttg
    24661 atcagcattg tgacttcgtt gatcacatta tggatcgttt ggtaggagat gacgggaaat
    24721 gaaaaaaata tcaacatatg aaaataagaa agtgcttgtc ttaggactcg caaaaagcgg
    24781 agtaagtgcg gccaaattat tacatgaatt gggcgcactt gtcaccgtta atgatggaaa
    24841 accttttgac gaaaatccgg aagcacaaga gctgctttct ttagggataa aagtaataac
    24901 aggtagtcat ccaatcgaat tgttggatga agaattttca ttgatggtca aaaatccagg
    24961 gattccctac agtcatcctt tagtagcaaa agcccaagaa atgggtattc cggtaattac
    25021 ggaagttgag ctagcttacg aagtagcgga atgcccaatt attgggatta caggaacgaa
    25081 cggaaaaaca acgacaacaa cgatgacagg actactactg aatgcaggag cagatcaagg
    25141 aattgcacgt ttagcgggta atattgggta tccagcaagt ggtgtagcgc aagaagcaaa
    25201 atcagaagat aaaattgtga tggaattgtc tagcttccaa ctcatgggaa tcacagattt
    25261 ccgccctcat atagcggtga ttaccaatat ctatgaagca catattgatt atcatggtac
    25321 aagaaaagaa tatgtcaaag ctaaatggaa ccttcaaaaa aacatgacag aaaaagatta
    25381 tctgatcctt aactggaatc agtcagaact acaagaatta gcgcaaagaa caaaagcacg
    25441 cgtactgcct ttctcgacaa aagaagtgtt ggaagacggt gtgtatgctg acgattactc
    25501 aatatactat aaaaaagaaa aaataatgga aatatctgaa cttggcgtac caggtaagca
    25561 taatgtagaa aatgcactag ctgctatttc tgtagcaaaa ttgtatggta tatcaaatga
    25621 agctatacga gaaacgttgc attttttcca tggcgtacca catcgtacgc aatatgtagg
    25681 agaaatccaa ggcagaaaat tttataatga ttcaaaagca accaatattt tagcgactaa
    25741 aatggctcta agtggatttg aaacgtctaa ggtcgtgtta ttggctggcg gattagacag
    25801 aggaaataca tttgatgaat taattccttc attaaaagga atcaaagcaa tggtcgtatt
    25861 tggccaaaca aaagaaaagt tgatggatgc tggaaaaaaa gcaggcatcg agacaatagt
    25921 aacagccgat tctgtagaac aagcagttcc tttagcatta gaaaacagta cagatggtga
    25981 tgtagtttta ttatcaccag cgaatgccag ctgggatcaa tacccaaatt ttgaaactag
    26041 aggaaacaga ttcatggaag ctgtgaaccg attaaaatag aaaaagtaga agcgagcgat
    26101 aaaaaatgaa aattttggtt acaggcggag gaacaggggg acatatttat ccagctcttg
    26161 cctttgtcaa ttatgtaaag actcaagaac cgaatgctga attcatgtat gtgggagcaa
    26221 aacgaggtct agaaaacaaa atcgtccctg atacaggaat gcctttccat accttggaga
    26281 ttcaaggatt taaacgaaaa atttccatgc ataacatcaa gacggtccga ttgtttctta
    26341 agagtatccg tcaagcaaaa aaaatcctca gtgattttca accagatatc gttatcggta
    26401 ctggaggata tgtttccgga gcggtagtgt acgctgcagc caaaatgggt attccaacag
    26461 ttatccatga acaaaacagt gtaccaggtg ttaccaataa atttttaagc cgatatgtgg
    26521 atcggatcgc tctttcattt aaagatgcgg cttccttttt tcctgaaaac aaagcagttc
    26581 ttgtaggtaa tcctcgagca caagaagtag cagatactaa aaaatcagat attttgaaaa
    26641 catttgattt ggatccagaa aagaaaacag tcttgatttt tggcggtagt caaggagcac
    26701 ttaaaatcaa tcaagcagta tcagtttttt taagtgaata tattccttct tcttaccaag
    26761 ttttgtatgc ttcaggagat agatattatg aagagatcct aaataaaata aatcctgaaa
    26821 tacaaaatat tagtgtccag ccttatatca aaaatatggc agaggtcatg gcttccagtg
    26881 atctgctggt ggggcgtgct ggtgcaactt cgatcgcaga attcacagct ctggggttac
    26941 cggcagtgtt ggttcccagc ccatatgtta cgaatgatca tcagactaaa aatgcaatga
    27001 gtcttgttca cgcaggagca gcaaaaatga ttgcagataa tgaactaaca ggtgaatcac
    27061 taagtcagac agtcaacgaa atcatgggtg atgaagaatt gcaaaagcaa atgtgccgag
    27121 cttctaaaga acaaggaatc cctgatgctt caaaacgtct ttatgactta gtaaaacaaa
    27181 taatcaaaaa ataaaggcgg tggtcttagt gagtaagaaa aaagaaccaa aaaaattgtc
    27241 tcatccgtct tctgatgaaa acaatttgac tccttggcaa aaggctaacc gaaaatatct
    27301 ggcagaacaa gagatgaaaa accaagagcc aaaaaaagaa gacataacat tagatacacc
    27361 cctttcagat tctgaagaag aaaaaacggt tcaagaggaa cagcaagaag aaagccagtc
    27421 cgagaaaaaa atcgaatttt ttgaagagat caagcaaaag aaaaacggtg gaccatataa
    27481 cggttctttt ttgaaccggc tgcccaattt aaaaagtcaa cggcacaaag tactatttcg
    27541 tcggttagct ttgatcatca ctgtattggg tataccgctg atttttttga tctattatgt
    27601 ttctccttat agcaaattac aagcagttgc agtatcaggc aataagacag tcaacagcca
    27661 agaaatcatc tctgatacaa aattgtcatt aggagaaaat gtttggggac agtattttca
    27721 tcgatctact tatatcgatc gccttaaaaa agcacagcca agaatcgaaa cagcaaatat
    27781 acatttcaaa gggatgaatg aattcgattt ggatgtaaca gaatataaag agattgcttt
    27841 gatcgcaaaa aacaatcaat actacccagt gattgaaaat ggaacagtat tagatgaaaa
    27901 agtagcaaat cctacaaaaa atctccctat cttggaagag ttcaaagact ctgcaaaaat
    27961 caaagaatta acaaagcaat acaatcagtt atcatcagaa ttacaaaaag caatttctga
    28021 aatcaagtac acgccaagag caagcaataa aaatctgatc caattgaata tgaatgacgg
    28081 caatcaagtt attgtaaata tcaataatct tgcgaaccaa atgaaatatt attcgcaagt
    28141 agccaaagat atggatgaaa aaggtgtgat cgacatggaa gttggtatct tctcgcatcc
    28201 ttacggtagc actcaagaaa cggaagaatc gggccaatcg gaagaaacaa ctgaaagtga
    28261 agaaaatgcg gatcaaacaa acgaatcaag tgaagaggca gaaacgcaaa aagcacaaac
    28321 acctggatcg tctagcacaa acggatcatc tgattcaaat gattcaagtg aaacaagtca
    28381 aatagaagat aatccaagta caactccgtc aagtttaaat gaaaattgat aaaacaactt
    28441 taaaaagtaa gaatgtactt tctaaaaacc agtaatttat ggtagaattg gaagcagtga
    28501 atatatctat taataagtat attttaaaac ggacgctagt tgttcgcttg tatatggaat
    28561 agtaagtagg agggaatccc attcatggca aaaacaggaa tgtatgtagg ccttgatatt
    28621 ggaacgacat ctgttaaagt tgtcgtggct gaatatatcg acagccaaat gaatattatt
    28681 ggagtaggaa acgcaaaatc agaagggatt aaccgaggca ttatcgttga tatcgataaa
    28741 acggtccaag cgatacaacg agcagtacga caagcagaag aaaaagcagg tatccagatc
    28801 aaaggcgtaa gtgtcggttt gccagcaaac atgcttgaag tagaaaattg ccagggaatg
    28861 attgcagtta acggagattc aaaggaaatc accgatgaag atgtcagaaa tgtggcttca
    28921 gctgcccttg ttcgttcaat acctcctgaa cgtcaaatcg tgtcaatatt gccacaagat
    28981 tttactgtcg atgggttcga gggaatcaaa gatcctcgtg gaatgatcgg cgtaagatta
    29041 gaaatgtacg gtctgttgtt tacaggacct aaaacgatca tccataacat acgtaaatgc
    29101 gtggaaaatg ccggattaat cgtcaacgaa atggtgatta ctcctttagc gctgactgaa
    29161 tcaattcttt ctgacggaga aaaagatttt ggtacgatcg tcattgatat gggtggcggc
    29221 caaacaacaa cggctgttat gcatgataag caattgaagt ttaccaatct tgaccaagaa
    29281 ggtggcgaat ttgtcactaa agatatctct attgtattaa atacgtcatt taacaatgca
    29341 gaagcgttga aaataaacta cggggatgca tacccagaac ggacatcacc agatgaagaa
    29401 tttccagtag atgtgattgg tcagtcagaa ccagtgaaag tcgatgaacg ctacttgtca
    29461 gaaattattt cagctcgaat ggaacagatt ttcaacaaag caaaagatgc attggaccaa
    29521 atcgaagcat tagagttgcc aggtggcgtc gtattgacag gcggagctgc tagtcttcct
    29581 ggtgttgtgg acttggcaca agaaatcttc ggcgtaaatg taaaattgta tgttccaaat
    29641 cacatggggc tgagaaaccc ggtatttaca aatgtaataa gtatcgtgga ttattcagca
    29701 aacttgagtg aagtgtatca attggcaaaa attgctgtta cgggtgaaac ctcagcagct
    29761 cgtcaaatgg tagttgaaca agaaacaaca aacacatatg agagctatga agcacctgaa
    29821 gaaacaatct acgatgagcc ggaaccaaaa gagtccggag aaaatgtaaa aaataaaatc
    29881 aagggtttct ttacaaatat ttttgattaa ttcatcctgg gaggaataag atatggaatt
    29941 ctcaattgat aataatatca atgacggcgc agtaatcaaa gtcatcggag tcggtggtgg
    30001 cggtggaaat gctgtaaacc gaatgattga agaaaacgtt aaaggtgttg aattcattac
    30061 agccaacaca gacgtgcaag cattaaaaaa ttcaaaagct gaaacagtta tccaattagg
    30121 ccccaaatat actcgtggtt taggtgctgg ttctcagcca gaagttggac aaaaagcggc
    30181 agaagaaagt gaacaatcct tacgcgaagc tttagacggt gcagatatga ttttcatcac
    30241 tgcaggaatg ggtggaggaa ccggtacagg tgctgcacca atcgttgcag gtatcgcgaa
    30301 agaattgggc gcattgactg ttggtgtcgt gacacgtcca ttcacttttg aaggaccgaa
    30361 acgtggccgt tttgctgcag aaggtatcgc tcgtttgaaa gaaaatgtgg atacattatt
    30421 aattatctca aataaccgtt tattagaagt tgtagataaa aagacaccga tgcttgaagc
    30481 tttccgtgaa gcagataatg ttttacgaca aggtgtacaa ggtatctctg atttgatcac
    30541 agcgccaggt tacgttaacc ttgactttgc tgacgtgaaa acagtgatgg aaaaccaagg
    30601 tacagcattg atggggatcg gtgtggctag tggagaagat cgcgtagtag aagcaacgaa
    30661 aaaagcaatc tcctctccat tgcttgaaac atctattgat ggagctgaac aagtacttct
    30721 taacatcaca ggcggtttgg atatgacatt gttcgaagca caagatgctt cagatatcgt
    30781 agcaaatgca gcaactggcg atgtaaatat cattctaggt acatctatca atgaagaaat
    30841 gggcgatgaa atccgtgtga cggtcatcgc aacaggtatc gatgaatcaa aaaaggaacg
    30901 caagtctagc cgaccagcta gacaagcaca aatgcaatca cctgctcaaa agactgtatt
    30961 agatatggat caagctaaac caacttcttc agaagaagaa aacagttttg gcgattggga
    31021 tatcagacgt gaacaaaatg ttcgtcctag agttgatgat tccaattttg acaatatcga
    31081 aaaaaaagaa tttgatacat tcaaccgcga agaaacaaaa tctcatggcg atgatgaatt
    31141 aaatacgcca ccgtttttcc gtcgtaaaaa ataaaggaga ggaagagcac atgattgctg
    31201 acaacttgca gaaaatcaag caagaaattc aggattcgtg tgctcttgtt catcgtgatc
    31261 cgaaagaagt tacattagta gctgtaacaa aatctgttga atccgctcaa gctgaagaat
    31321 tggttagagc tggcgttatg aattgtgcag aaaaccgagt agataaatta ttagaaaaga
    31381 aacaagattt atttgatttt cctgaaataa agtggcattt aattggtaat ttacagcgca
    31441 gaaaggtaaa attgattgta aatgaaattg attactttca tgcgttggac agtttaagat
    31501 tagcagaaga aatccagaag cggttagaga aagaattatc ctgttttatt gaagtaaatg
    31561 tttctggtga ggaatcaaaa catggaattt caccagatga gcttttaccg tttgtggaat
    31621 ctttagctgc ctgcacaaaa atcaaggttg ttgggttgat gactatggcg cctaaagaag
    31681 cttctgatga gcaaatccat aaagtgtttg gtacgctgaa agaattgcgt gatcttgttc
    31741 aagcaaaagg ttatgcccat gcaccatgta gtgaattaag tatggggatg agtcaagact
    31801 ttcaaattgc gattgaagaa ggtgcaacat ttatccgtgt aggaacagcg ctattcaaag
    31861 acgaataaag gaggaacaaa aatgccgctt ttaaacagag gagcaattgc taattttttc
    31921 ggattagctg atgaggaaga gtacgaatac caagattatc ctgaaacaac aaaaaaggct
    31981 gtacagccaa ctaaaaaaaa tacaacacag aatcaatcaa ctcattctgt atctgctgcg
    32041 aatactcatg aaaaacaaaa aacggcgact tcacgtcctg taacgcatga aagtattcag
    32101 ccggctgaaa agaaaaaagt aattgaacta catcaatcac ctacaaaaac tgtagcgaaa
    32161 gaaagaacag cttcaagaac ctctacacaa cctaaagcaa atcttgctgg aaaaatcact
    32221 gtaatggaac caagagctta ttctgaagct atggcgattg ctaaacgaat cattgctgga
    32281 gaagcaacct tagtgaattt tcatttagta gaagaaaaac aagcgagaag aatcgttgat
    32341 tttctaacag gaacagttta tgcactagat ggagatatca aacgtgttgg agatgagatt
    32401 tttctttgta caccgactgg gatggagatt gacagttcaa ccgctcaatc ttttgcagat
    32461 gcgaatttgt ttgatctgta agaggaggaa ctacgattta tactattgca ctattacttc
    32521 atttacttca acgggcagcc tatttctata gcattatctt gatggtatat gcattgctct
    32581 cttggtttcc aggcgggtat caatcagggc taggacgatt attagctaag atctgcgaac
    32641 cgtatatcag tttgttcgat cgtctgcctt tgaggattgg acccttggat ttcacaattt
    32701 taggggcaat cctgatcttg aacttagccg tacaaggttt agcacagatc gttatatgga
    32761 taactgtcca tttagtttat tgattgaagc aacaaaatct ttattctcag aatagatagg
    32821 aggggaaaat tttggatgca aatgtatacc agcactttcg ggcagatgaa cgtacattta
    32881 tcgattcggt aggcgattgg attgaacagg ttcaaggaca atatgcaccc tatctgaccg
    32941 aatttcttga cccaagacaa tcctatattt tagaaacact gattcgacaa agcagtgatt
    33001 tgcgtttcat gttttatggc ggatatgaac aggcagaaag aaaaagatgt ttgattttcc
    33061 ccgattatta cgaacctgta gaggaagatt ttgaaacagc attgtatgaa atccattatc
    33121 ctagcaaatt tgccagccta agtcatggga aaatccttgg aactttagtg ggaacgggga
    33181 tcaaacgctc ttactttggc gatatcatct cggacggtga tcgctggcaa gtatttattg
    33241 caaatgaggt ggatcatttt gttgctgcac aagtaacaaa gattggaaag gttgctgtac
    33301 gcttggaacc aatcaaatac acagaaatga ttatgccgaa agatagctgg acacaagaaa
    33361 gaggaacagt tagttccatg cgactagaca gtgtgatctc tgagatttat aatatttcca
    33421 gacagcggtc caagcagctg atcgaagctg gtaaagtaaa agtgaactgg acagaaaata
    33481 caagacctga ttttgtactt gaactattag atattatttc agtcagaggt tatggcagag
    33541 tccagatcca agaacttgag gggaagacga aaaaagaaaa gtacagggta ctgttcggtg
    33601 tattacgtaa ataaaataaa aaggtggttt actcatggct ttaactccat tagatatcca
    33661 aaataagaca ttcccgacaa aaatgcgggg atataatcaa gacgaagtag atgatttctt
    33721 agatttagtt gttcgtgact atgaggaatt gactcaaaga aatcgagaat tagaaaaagc
    33781 agtcaaacat tctgaagaaa aacttgagta cttcaatgaa ttaaaagatg ctttgaacca
    33841 atcaatcatc gtagctcaag atacggctga taaagtaaaa acaagtgcaa gcaaggaatc
    33901 cgaagtgatc gttacttctg cacaaaacaa agcagatgag ttagttgcga acgctgaaaa
    33961 acgtgcacat caattaacaa ctgatgcaga agaaaaagca agaaaaatct tgacagatgc
    34021 aacagaaaaa gcaagacagc ttgcgacaga aactgaagat cttaagaaaa aaacacgagt
    34081 attccatcaa cgtatcagct tgatgcttga gtctcaatta gaacaagtga aaagtccgga
    34141 atgggatgaa attttacaac cattctccag ctacgtgact gacagccatg aagtgatcaa
    34201 agaagtttta gcaaaacagc ttgacaatga aaatgatact gatgtaaact cagacacagg
    34261 agtcatagaa gcacctatga cggcatttga tacacaggct attgatatct cgatcgtgcc
    34321 tggtgaaaat gaaaacgagt agaacagaaa agcactttgt tattcttaaa gcgagccgat
    34381 gagagtggaa gttcggtaag acactgcatg gtgaaagatc ctctacttga gacctgcttt
    34441 tccgaaatta gagtaagaag cagcggctga cctcgttatt ggtcacagag agtttgcact
    34501 agatagatgc aactaaattt gggtggtacc acggcatgtt cgtcccttgc ggctgaacat
    34561 gcttttttgt gtccggaaaa caaataaagg agtgtatggt tgaatgaaaa tgaaagaaac
    34621 cttgcaatta ggaaaaacaa aattccctat gcgtggtaat ttgccaaacc gagaaggcga
    34681 gtggcaaaaa gaatgggaag aaaatcgaat ctaccaaaaa agacaagagt tgaacgaagg
    34741 aaaacctagc tttgttcttc atgatggacc tccatatgcc aatggtaata tccatttagg
    34801 acattcattg aataaaatca gtaaagacat tatcattcgt tcaaaatcaa tgtctggcta
    34861 tcgtgcacca tatgttccag gatgggatac acatggattg ccgattgaac aagtattggc
    34921 taataaaggc gtgaaacgta aagaaatgtc catggcagaa tacttggaaa aatgtcgtga
    34981 atatgcactt tcccaagtag ataagcaacg agcagatttc aaacgcctag gagttgcagg
    35041 agattgggaa catccttatg ttacattaga tccttcttat gaagctgcac aagtacgcgt
    35101 atttggtaaa atggctgaaa aaggctatat ttacaaagga ttgaaaccaa tttactggtc
    35161 tccgtcaagt gagtcttctt tagcggaagc tgaaattgaa tataaagatg taaaatctcc
    35221 atctattttt gtagctttca atgtcaaaga cggcaaagat attcttgatg aagatacagc
    35281 ttttgtcatt tggacgacaa caccatggac attgccagca aaccaaggta ttgctgtaaa
    35341 tccaaaattt acgtatgtat tggtggaagc cgatggccgt aagtttgtcg tagcgaaaga
    35401 tttgctagaa acagtccaat cagaaatcgg ttgggaaaat gtaacagttc taaaagaatt
    35461 tgctggacaa gaaatggaat atatgactgc aagtcatcca ttctatgaac gtgaatcact
    35521 tgtgatttta ggcgatcatg ttactttaga cgctggtact ggattagtcc atactgctcc
    35581 aggacatggg gaagatgact atatcgctgg tagcaaatat aaactatctg tagtgtcacc
    35641 tgtagactca aaaggattgt ttacagaaga agcacctgga tttgaaggta tcttttatga
    35701 caaagcaaat cctatgatca ctgatctatt aaaagaaaaa ggagctttgc tgaagctaga
    35761 tttctttact catagttatc ctcacgattg gcggacgaaa aagcctgtga tctatcgggc
    35821 aactccacaa tggtttgcat ctatcgataa attccgtcag aatattttgg atgaagtaga
    35881 aaaagtagag tgggttatcc catggggtaa aacacgtttg tataatatga tccgtgaccg
    35941 cggcgattgg gtaatttccc gtcagcgtgc atggggagta ccacttccga ttttctatgc
    36001 tgaaaatgga gaagcaatca tcacaccaga aacaatcgaa catgtggcaa aattatttgc
    36061 tgaacatgga tcaattatct ggtttgaaaa agaagcgaaa gaacttcttc ctgaaggatt
    36121 tacccaccca ggttctccta atggcgaatt tacaaaagaa aaagatatca tggatgtctg
    36181 gtttgattct ggttcttctc atgaagctgt tttacgtcag cgaccagaat tatcattccc
    36241 agcagatatg tatttagaag gatcagacca atatcgtggc tggttcaact caagtatcac
    36301 gactagtgtg gctatcaatg gtgtagcacc atacaaatca gttatttctc aaggatttgc
    36361 tttagatggt gaaggccgta agatgagtaa atctttagga aacatcattg caccagaaaa
    36421 agtgatcaaa caatttggtg cagatatcct tcgcttatgg gtatctagtg tagattatga
    36481 agcagatgtt cgtgtttcta tggatatctt aagtcaagtg gcagaagtat atcgtaaaat
    36541 cagaaatacg atgcgtttct tattagcgaa tacagaagat ttcgatccta aaaaagatac
    36601 tgtttcgtac aatgatttac gttctgtaga caaatatatg accgttcgat tgaaccaagt
    36661 aatcaaagaa atccgagaag aagggtacga caaatataac ttcatgcata tttaccgtac
    36721 agttatgaac ttcttgacgg ttgatctatc gtcattctac ctggattttg ctaaagatgt
    36781 agtttatatt gaagcagaag atgattatca acgtcgttgc atgcaaactg ttttctatca
    36841 aacagctgta gctttgacaa aattattgac tcctatcatt ccgcatacag cagaagaaat
    36901 ctggtcattc ctgaaagaag aagaggagta cgttcagtta agcgagtttc ctggttatga
    36961 agagtttgca aaccaagaag aattgatgga tacctggact gctttcatgg acttccgtga
    37021 taatgtctta aaagcattgg aagaagcaag aaacagcaaa ttgattggta aatctttgga
    37081 agcaaaacta actgtttatc caaaacaaca agttcgtgaa atgttaaaag ctttggatgc
    37141 agatattgca caattattga tcgtttcacc agactacttt gaagttatgg cagcagatga
    37201 acaagtgcca gataacgcta tggtatttga tgatgttgct attacagtgg aaaaagcaga
    37261 cggggaaact tgcgatcgct gtcgccaagt tcgtaaagat gtaggagtag atgaaaaact
    37321 tcctcatcta tgcggtcgtt gtgcaaaaat cgttgaagac ttctatcctg aagctgtagc
    37381 tgaaggattc gaagaaaagt aaaagggaaa agggggtgtg acatgttctt tgtcacaccc
    37441 ccttttgtta tcaatcgttt aattttccac gttcacgata ccagttatct ggttgccaga
    37501 tccattcgaa tccgtctttt tcaagtagtt cgaaagctgc tttaggtccc attgatccag
    37561 ctttgtagtt gggaaaatcc ggttgtgttt ggtcccaagc ttttcgaatg acatccacga
    37621 tatgccaaga ttgagcgact tcttcccaat gagagaagtt cgttccatca ccattcaacg
    37681 catctaatag taatttttcg taagcttctg ggctattttc aaccatttct gcactatttc
    37741 taaattccaa tttgattggt tccgtttcaa atccttgccc tacttctttc ccattcaagg
    37801 ataaagaaaa tccttcagtt ggctgaatat agatcgttag aacattaggt ggaagtgtcg
    37861 tatcgtcaca tggttcatcg acagatgttt tgaatacatt aacaggaact tgtttgaata
    37921 cgatgttgat ccgagtccct ttttcagtca aacgtttgcc tgtacgtaca tagaaaggaa
    37981 cacctgacca acggaagtta tcgatagtga atttgcctgc gacgaatgtt tcagtctctg
    38041 attgagcatc cactttgtct tcttcgcgat agcccttgaa ttgtacacca tccaattcac
    38101 cttgagcata ttgcccgcga acgaagtttt ctaacacttc ttcttcgtta taaatgcgga
    38161 tagctttcaa tgctttgatc ttttctgtac ggatttcttt ttcggaaaat gctactggcg
    38221 gttccattgc aagtaatgct acaacctgta aaatatgatt ttgcaccatg tctttaagtg
    38281 cgccactatg atcgtagtag cccccgcgat cttctacacc gaggttttcg ccaaaagtaa
    38341 tttggatatt gtcgatatag cgattgttcc attgagcctc aaaaatatta ttggcaaaac
    38401 ggatagctga gatgttttgg atcatttctt ttcctaaata atgatcaatc ctgaaaatat
    38461 cttgttctgg gaatacttct ctgatttgct ggttcaattc aaaagcagac tggtaatcag
    38521 aaccgaacgg tttttctatg atcaaacgat tgaagccatt ttttgtcata atattttgtg
    38581 atttcaaatg agaaacgatc gttccaaaaa attgaggtgc catagccaaa taatagacac
    38641 ggttaccgtt taattgatag tgtccatcta atcggtcaga caattctttt aatgtctgat
    38701 aatgcgttga atcatttaca tcatgggatt gatagtaaaa atggcttgca aaggtagttg
    38761 cttcttcatc tgaaggattc aatgcacgga ttgtttcttt gacaacttca cggtagtgct
    38821 catcgctcca gggacggcga gcggttccga ttacagcaaa atgctcgcct aaatttcctt
    38881 ttctgtaaag gcggaacaaa gacgggtaca atttacgctg ggctaggtca cctgtaccgc
    38941 cgaatatcgt aaacaataca tttttttcat tagacatgtg gatacactcc tttatatttt
    39001 atcgacaaaa atcgtgctgg ccgccttaaa gctgacgggg attttctttc tatcattttg
    39061 gatagtgatc ggtccttcat aagctgcgat gtcaacgatc tcatattctt cgttgatatt
    39121 caggtcaata gtgactaagt aatccaacaa ttctttttca tcaagcactc gtgcgatacg
    39181 cacttttgta ccgacaggat aggactccaa tgtttgtcgg cgttcttcat ggacaacttc
    39241 ctctttttta ggaatcgatc ctccatgagg acaatgttca ggatgattca aatagttttc
    39301 taaatgatct gcaagatgtt ccgaagtcac atgttccaat acttcagcat catcatggac
    39361 ttcattccag ctatagtcta aatgttcaac taaaaaaact tcccataagc gatgtttgcg
    39421 aatcagactg ctagcttttt gcagtccgct tgcagtcaat tgtacacctt gataagggga
    39481 atgttctaca agctcttctt tcacaagttt agaaatcatt tcactgacag atgcagctga
    39541 gacatctaga ctagatacga tttgtttatt gttgactttc gttgtatctc cacctagttc
    39601 taaaatgatt ttcaaataat cttctcgatt tggtgtcata ttcgatcatc ctttcatggt
    39661 aaaaaaccat cattagtaag tgtaacaaaa aaaacgttaa ttgactattt ttctaaataa
    39721 aaaacaaagg atttttagac gtttttacaa caaaaaacga aagatgatag agaagactca
    39781 ttctttcgtt tataaaggat atatatatac attgggaggg atctattttt cagataacaa
    39841 cttatatgaa gtgtctgcag attcgtcata aagagtttgt tcgggataag aaaagataag
    39901 ataaaaacca tactgatcac gtacgactaa acgatattca tctatttcta ccacagatgt
    39961 gccaagagac tgaccgttga tcaaaaacgt gtaatcagat gtaatctgta attgttgttt
    40021 ttgctggcta tcactaaaga accatgtacc ttgatacttt gagagtcctt ctgacttttc
    40081 cgcttgtttt ttctttttca agtaaataaa acttgagaga acggtaatga gtgaaccaag
    40141 aaaatagatc atttttttta tcaccaaatc actcctttat gagaaaataa tcgcatagac
    40201 atattctttc ttctttattt cattgtaccg aataaaagct aaaatttctc taagactttc
    40261 gactggtttt tttactgttt ttctacaaat tatgatagga tacatagtag gaagaaaggt
    40321 gacataattt gaagtatcag caagtggaaa tagctttttt tattgaccgc ccgaatcggt
    40381 ttatagcaca ttgtatgaaa aaagacggag aaataattat tgcgcatgtc aaaaatacag
    40441 gtagaggaaa agaggtcctg ataccaggcg ctgaagtggc tattgtattt gctcctggac
    40501 ctaaacggaa aaccgcctat gatctgattg ctgtaaaaaa gaagggtgac tggtttaata
    40561 tcgatagtca attgcctaat cggctggcaa ttgatggtat tttagacggc acgatccttt
    40621 taccaggatt aactggtcca tttacggtat acaagcgtga agtaacttat cttcactcca
    40681 aatttgatat ttatttagag acggtggtcg gacaaaaagc atttgttgaa gtcaaaggta
    40741 tgacacttga aaataaagcg attggtgctt ttcctgatgc gcccacactc agaggattga
    40801 aacatatagg agaattaacg tatgccgcac aagatggtta tgccgcttat gtcttgttta
    40861 ttgctcagtt cgaacatctt catctggcaa cgatccatga agaaatgcaa ccagcactag
    40921 ctgatatggt tcgacatgcg cagcaaagcg gagttcaaat cctcgcctat aattgtcaag
    40981 tatcggcaga tgaggtaact gtcaagcagg ccattccatt tgatgtagat atcccttttg
    41041 aagatcctat acaatagaaa gaaggtaaaa taatgatcaa cttaggtatt atcggaacaa
    41101 attggattac tcatcaattt gtccaagcag ctttaagcac aaaaaaatat gaattgacag
    41161 cggtatattc tagacatttg gaaaaagcac aggaatttgg ttctcattat gaaggggata
    41221 tcgaattcgc aacagatttg aagacttttt tcaatattac tcatatggac accatttata
    41281 ttgcttctcc gaatagtctt cactttagtc aagctaagca agcaattttg gcaggaaaaa
    41341 atgtgatagt tgaaaagcca gctttttcga cgccaaaaga aatggatgaa atcatccatt
    41401 tggcaaatga acacaatgtg tatttttttg aagcagcaag aaatatccat gaatcaggtt
    41461 ttaaaaagat tgccgattac ttaccattaa aagacgagat aatcggtgca aatttcagct
    41521 atatgaaata ttcttcgcgc tatgaccaag tattagatgg agaagaaccg aatatcttct
    41581 cgactcattt ctcaggtggt gcattgatgg atttaggtgt ttaccttgta tatgcagctg
    41641 ttgcttggtt tggaatgcca aaagaagtcc attatttccc aagaaagatt tctactggtg
    41701 tagatggtct tggatggggg atcttacgtt atgagaattt tgatgtatcg atccagccag
    41761 gtaaaatcgg tgattcttat ttaccgtcag agatttattt tgactcagga acgctagtga
    41821 tgaatggagt caatgcaatt gaacaagcac aatttcatga tcgcgcgcat aaagaaatca
    41881 ttgatttggc ggtaacagct gcagaaaatc caatggcaga tgaagcagag gattttgcca
    41941 atgtcatggc tcatccgaaa gatccagctt ggggattgtt gtatgaagag tggatcgagc
    42001 tagctagaaa tgtgaaccaa gtgatttatg atttaagaaa aaatggcggc atcaaattcg
    42061 atgcagataa tgaggaagat ttttaatgaa cgaatttgta caagtatttc ccgaaaattg
    42121 gcagaaaaaa tatgaggata aagggtttat ctcaccttct cttattcaac gagcagtttt
    42181 tcagccacta agtaataaac aaagtatagt agcggtttct cctacaggtt caggtaaaac
    42241 actggcttat ctttggcctc tactactaaa cgtggaacca ggtgaagcaa gtgcgttggt
    42301 catttttgct tcttctcaag aactagctat tcaagtagca gatgttgcac gtgaatgggg
    42361 aaaagacaaa gagttgaaag tccaatcttt ggtgggcgga gccaacgtca aacgtcagat
    42421 tgagggtttg aaggaaaaac cagaaatctt gattggtaca ccaggaagaa tattggaatt
    42481 gatgaaagca aaaaaaataa aagcacatca agtgaaaaca atggtatttg atgaagcaga
    42541 ccagctattt gacgctggga acagccaaat cattgatcaa attcttcatc aagctccaac
    42601 agagtatcag ctagcttttt tttcagcgac agcagatcgt tcccttgaaa gcattgaaaa
    42661 aatcactggg aaaacgtttg agacaattga cgtgacagca gaggacgatt ctcgaaaagg
    42721 actgagacat tactttttac gtgtaccgat acgaaagaaa gatgactact tgagacgtct
    42781 cacgcatata gaagattttc atggtctgat tttctttaat caactgactg aattaggcgt
    42841 aatggaagaa aaattgctgt atagaggtgt accggtagga agtctggcct ctgatcagaa
    42901 caagctactc cgaaaagcag cgctagaaca attcaaaaag aaaatggtca gagcactttt
    42961 gaccacagat gtggcggcta gaggtttaga tattacaggt cttccttatg tagtgaatgc
    43021 agaagttccg ttaagtgaag aagcttattt gcatcgttcg ggaagaactg gtcgaatggg
    43081 taatgaagga atagtaatta cactcgtaca agataataat ctaagagatt taaaacggct
    43141 tttacgtcca tcaaatataa cacttgaaga gattttttta tacggaggta agctgcaaac
    43201 tgagcagcca accaaagaag atgcagctcc tgcagtaaat aaaaagtatg cgaaaacttt
    43261 ttctggaaag gagcagaacc cagaatataa caaagaaaaa ataagaaaaa aagttaaaaa
    43321 taaatcaaaa aaagagagaa ataaaggagc aaggcgcaaa taagcgcctt tttatgctat
    43381 gattatgaaa acgggaacaa aattggttgc cagaggaggg gttatgtgaa agaacgtcaa
    43441 gaagagatct tgcagctatt gacagaaaac caacaaggat tgacagcaag tgatgtagct
    43501 gagcgcttaa ctatcgatcg aagcaatgca agccgatatt taagtgaact atacaaggcc
    43561 catcatattg taaaaaccgc tggccgacca gtcgtttact ctttgccaac ggaaaagtca
    43621 aaatctgatg aagtgcatgt cgactcttct acgcaagtga cttttgaaac actcgttgga
    43681 gaaaatgatt ctttaaaagt cagcatacag caggcaaaag ctgcgattct ttatccaccg
    43741 cgggggttgc atacgattat ttttggagaa actggtacag ggaagtcgat gtttgctgaa
    43801 tgtatgtatc attttgcaat cgattcagag atgctttctg cagatgcgcc atttgtttct
    43861 ttcaattgtg cggattatgc tcaaaatccg caactgctct ttggacacat ctttgggatc
    43921 aaaaaagggg cttacacagg agcagctcaa gatagtcccg gtctaatagc caaagcagac
    43981 ggcggtatat tgtttttaga tgagatccac cgtttaccgc cggaagggca ggaaatgctg
    44041 tttactttca ttgataaagg tatttaccgt ccgcttggag aaagtgcaca agtacatgaa
    44101 gcatctgttc agatcattgg ggcgacgact gaatcttcag aaagtttctt atctacgttc
    44161 aatcgacgga ttcctatggc aatcaccttg ccgaatcttg cttcacgttc actggatgag
    44221 cgttatgaaa tcatctctct ttttatcaaa caagaagcga atcgtttgaa tcaacgtatc
    44281 gatatcgaaa aagaagcgat tcttgccttc atgctttatg atgcggaagg aaatatcggt
    44341 caagtgaaac gagacttgaa actagtctgt gcaaaatctt ttttacatta ccgtactcat
    44401 catgagaaaa agctaatcat tcgaaaagaa gaactttccc ttcaagtaca aaaaggatta
    44461 ctgaaaatca aggaaatacc ggaacgtctc gaccgattca tggacagcaa aagtcagtat
    44521 ttgacatttg aaccaggatt tgctgatgtt gtctggtcac aagatccaga acgaaacatg
    44581 caggtctata acgatattga ggaaaaagtc acttctcttt ccgaaaccgg tgtggagaac
    44641 attgatctag agaccctcat ttcaaaagat gtggatgctt atttccagac atatgtcaaa
    44701 gaattgacta aaagttcgat tcccaaagat cttttgccag atgaaatctg gcggttaacc
    44761 aatcaattgt atgatgtggc tgaaaaacgg ttagaccgta tttataatga aaaagctcgt
    44821 tttgcttttg ctttgcatct gcaaagtaca ttggatcgtg tgagagaagg tcatatgatc
    44881 gtccacccag atttgaataa cgtacggaaa aattttaaga gggaattcca ggtagcaatc
    44941 gatctttcaa cgatcattga agaagaagaa caagttgaga ttccttttga tgaaatcggc
    45001 tttattagta tgtttctttc tatcaatcta ggagaaagtg agcctgttaa agaaaacaaa
    45061 gtagatgttc tcatattgat gcacggcaga cagactgctt caagcatgtt ggagatggca
    45121 caagaactat taggaacaaa agtagggaaa gcttttaata tgccactggt tatggaagtt
    45181 caaacaatgt atgaagaagt gttacaatat gtcaaaaact atcaagagca tttgacgaat
    45241 ggcctactct tgttaacaga tatgggatca ttaaacacct tcagtgattt gatttatgaa
    45301 gagactggca ttcggacgaa agctatcacg atgacaagta ccatgattgt gatagaagcg
    45361 atacggatgg caagtgttgg aagaagctta gaagatattt atcaaaatat ccagctttcc
    45421 tttgaatcga tcgtacgtga tcagttcaaa gcggaaaagt ctgaaacttt acagcgtaaa
    45481 aaagccgtaa tcgtgacatg ctttactggt gaaggagtag ctgccaaatt atatcagcgt
    45541 attatgccag tgattaatca aaataaggta gaactgatcc agatgcagtt tttagaacgt
    45601 gaatcattca aaaaacacat cgatgcctta ttggaagaat atgagatcaa agcaattgcg
    45661 ggaacagttg atgttgatta tcaaaatatc ccattttttt cagcctatga cgtttttgat
    45721 gatgaaaaac taaatatttt aaagcgtata gctgatgatg agatcccgac agctaaaatt
    45781 gtcgattcac ttgctggatc attaagcgat gtcttttcta ttgatgaact gatccgttca
    45841 ttgcaaaaga cagttcagca gatccagacc gatttgtcga ttatcgtgga acctggagta
    45901 gatactggaa tcgttatcca tttagccttc atgttagacg gattgatcaa acaagaaagc
    45961 catcggcaat ttgagaaact gtctattttc tcaaaaattt atcgtttgga aatggatatc
    46021 gttcgggcaa acttgatggc actagaacga aaatatcagg taaaaattcc agaagatgat
    46081 atcgcatttc ttacacaaat gtttcttgaa aataaaataa aaaaatgaac acactaatca
    46141 tactgtttac acactaaaca tctgtgtgcg cactataaaa aagagctaaa aagcatgaaa
    46201 acgctatttc agctcttttt tttattggca tgcttcttgc gttatataaa agtgtaaaaa
    46261 aataaaagga gtgttaaaaa tggcaaaaaa aacaatcatg ttagtttgtt cagcagggat
    46321 gagtacgagt ttattggtca caaaaatgca aaaagcagca gaagaaaaag ggatggaagc
    46381 cgatattttt gcggtctctg cctcagatgc agataataat ttagaatcta agaatgtcga
    46441 tgtattatta ttaggtcctc aagtacgttt catgaaagct caatttgaac aaaaacttgc
    46501 gcctaaaggt attccattag atgtcatcaa tatgcaagac tatggcatga tgaacggaga
    46561 aaaagttctt gcacaagcag aaaatctaat gaaataaatc aagtatgcag ttgggggtat
    46621 aacaacgtgg aagatcaaca aaatctagaa gccatcatgg ggttaatcat gtttggcggt
    46681 aatgcaaaga gcgatgcaat ggaagcgatt gcggctgcta aaatcggtga ttttgagtta
    46741 gcggatagga aaatcgctga tgcagaagaa tcacttatac aagcgcatca tgcacaaaca
    46801 gacatgttga cacaagaagc acaaggaaat catatgcaag tgacattatt gactgttcac
    46861 agtcaagatc acttaatgac atctattgcg tttactgatt tagcaaaaga aatcatcgaa
    46921 ctttatcgtc gcgtatacag cgaataaata caacttcttt tttgaacgga agaagaaaaa
    46981 tttttgaacg gattttttat tttgttataa ggagaactct ctttatataa aaaacttata
    47041 ggaggaagta aaaaatgaac ggactatcaa gttggatgga gaaatacatc ctgccggttg
    47101 ccgcaaaaat cggagcgcaa aaacatttag ttgctttgcg tgatgctttt atcggcacac
    47161 tgcccgcaac aatggcggga tcagtcgctg taatgatcaa tgcaattatt cgtgatttac
    47221 cgcaacagtt taacagtacc tatgctgaca gtttagcagc agacaaagga atctttgccg
    47281 tattgaatgt catcatcgga atcaatggtt ttgtctggaa cggtacacta gcaatcgccg
    47341 gattgatctt tgccttttct tgggggtata atcttgcccg agcttatgga gtaaatgatc
    47401 tagctggggg gatcgttggt ttagctacct tgattcaagg tatttccttt ggtccagcat
    47461 tatcagcagc attagatgtg aatgttcctt caaatgtcgc agatgcaatc aatagttctg
    47521 agattggtgc aacgattgca gatggcacac tgtcagttgg attatggggt tggctaaaac
    47581 tagatcattt gaatggaaac gcttatttta cagttatgat catgggagct atttcagtca
    47641 ttattttttg taaattgatg cttgccaaca ttacgatcaa aatgcctgat tcagtaccac
    47701 cagcagtatc taaagcattt gcagccattt taccagcgac gatcgcttta tacgtcattg
    47761 ctattatcaa ttatatcgta ggtcgtgtag ctgatgggca actgatcatt gatttggtgc
    47821 aaaaatatat tgcagaacca ttcctaggat tatctcaagg gttgggagca gtattgatcg
    47881 tcacagtatt tgttcaagta ttctggttct ttggtattca tggaccaaat gtattggcac
    47941 cagtgctaga gggaatctgg ggacaagcac aactaatcaa tattgatatt ttccaaaaag
    48001 gttataacgg aaaaactggt acaccagccg tgttagatgc aatcgaagat ggaaaagctt
    48061 atatgtgggt ccgcggatcg ttcgatgctt ttgcatggtt tggcggatca ggcggaacga
    48121 tcgtcttact gatagctatc ttgattttct ctaaacgtgc agattatcta acagtagcta
    48181 aattatccat tgggcctggt atcttcaata tcaacgaacc agtgatgttt ggtctgccaa
    48241 tcgtattgaa tgcaatcatg tttatcccat tcttgattgc tccagtagta gcaacagcaa
    48301 ttggatggac agctacttat cttggcctag tcgctccggt atcgcagcaa gtcacatggg
    48361 tagtaccgcc gttcttattg tcattcttag caacaggagc ggattggcgg gcaccgatcg
    48421 taacattagt atgtatggtc gtgactttct tgatttgggc accatttgtc atctctgcaa
    48481 acaaaatgga ccctgccgca ggcgaacaac aataagatga acgtgaggag cgggacgctt
    48541 taagtttcgt tcctcataat gaattttcta ggaggaactg aaatgattac aattgccagt
    48601 gcaatgcaac aagatgaaat caaagaattg ttagaaggat acaatgaaga aggaatgact
    48661 tttacattta aagaaaaaca aggaatcaag ctgttctttg aaacaagtgc agaagatccg
    48721 gaagttgcgg ctaaaaaagc aaaggaacta atcaaagcac agccttgggg aacagtcctt
    48781 tattttcaat caacagctgt ttagaaaatg gtttaaaaag ataggatggt tgagatgata
    48841 aaaaacggtt tatttttatg tagtattggt tctttgatcg tgttgtatag tttgaatcca
    48901 cattcgcaaa ggtatgattt gtatagtatg gtcacaggtc tttttctaac aggattagga
    48961 atctatttct tcatgaaggg gaaaaaaaga gaagaagcaa aggagaaaaa taactaatgg
    49021 aaatcacgaa aaaattaaat attccagcat cgttttttta cgataaagtt atggactctg
    49081 tccttttcga tgtacgtaaa gcgaccggca aatcagtaac tagaaaacag ctgaaaaatt
    49141 tggagtacgt caaacaattc tcgcaaaata accgggctcg cataaaaatc gaagaagtca
    49201 ttgaaaacca gtcttataag tttcgtacat cgacaacgaa gaatgaattc gtcgttcatt
    49261 atcaaatcaa accattggac gattcgacct gtgaggttca ttacacagaa aaaatggagt
    49321 cttatggcat gcttcaaaag ttgaatgata tgcttttagg aacaatcttg atgtatttta
    49381 aacggagacg tttcaaaaaa atgctagata tgatcgaagc aacgtattaa atcaatgaaa
    49441 catggtacta tttagttatt gaaaaatgaa gtaagctaga aggaattttt cataggaaga
    49501 tagatctttc ctgcgaatcc tcactagctt ttttgtagga aggggcagca aaatgacaaa
    49561 caaagtaaga gagctaggtg tatcttcgat tgaggaaatg tttgatttag ccacttatgc
    49621 atttaatggg gcagatacac ctgaaaggcg agaacgtttt cgtacacttg cggagaattc
    49681 ttggaattac ggattttttg atgaggagga tcggctaaca agtcaagtca tggcgacccc
    49741 ttttccagtg aatttttacg gacaagagta cctaatggcc ggcattggct atgttgcttc
    49801 ttatccagaa gcaaggggac aaggcgggat caatcagatc atggaaaaga tccttgaaga
    49861 ttgccgtgat cgtaaagtaa gcttatctta tctggcgcca ttctcctatc ccttctatcg
    49921 gcgctatggc tatgaacaat catttgataa aatcagttat caactaaaca gtcgtgatgt
    49981 gccgtttatc aaaaaaaaat ctggaaaaat aaagcgtatg gattttgaag atgcaaaagc
    50041 tgcaatcaga agaatttatg aacagatgcc ggaaaaccaa cgagctggtc tgaagcgcga
    50101 agactggtgg tatacgtata aattcaagca aaaaggcaat taccagtttg ctttgcattt
    50161 tgatgataat gaggaagcaa cgggatatat cgtttatcag cttgcaacgt cttcctttat
    50221 tattgcggag tggggatttt tggatcatga tgctttttgc agccttgttc gcttcgtaag
    50281 ttctcacaat ggtgcttttg aaacatttga atattcatgc ggctacggcg gtaatgatca
    50341 aaattatcta ttagaaaatc catttgcttc tgtaatgatc acaccttata tgatggcgag
    50401 gatcgtagat atttctttgt ttttggaaaa ttatccattt aaaaagagac aagctgcatt
    50461 tgccctacaa atagaagaag atcattatgc gaaatggaat gaaggaatcg tggaagtaac
    50521 aatcgaaaat ggaaaaaatc atctctcaaa agtagaacaa acaaaactcc caatcgttcg
    50581 aggaagtatc caacatatca cgcagctatt attagggtat cgtaaagtgg aagagttggt
    50641 attccaagaa agaatacagg tgacaaaaga atatgaagaa acgttaagct caatcttgcc
    50701 acagcaacag ccaattctta atgactattt ttgataaaaa acgggtgatg acaatatttt
    50761 tgtcaccacc cttttgtttt tcatttggca tttgaaggaa aatgttaaag taaatcctct
    50821 tttttcgtaa atttgaattt tttgttttct tttgttttag ggttttcttt tttgtggtct
    50881 tggattgctt ctttcgtaat cttttcccga ttttttttag atgaatctaa gcgttctgcg
    50941 tatacttttt cttttggctt atcattcatt ggaaaggacc tccctacatt atttcattct
    51001 acctctagtt tatcatctgt taaggactag tggaaacgtt ttgcctaact tataagctga
    51061 tttttttagc agataagctt gcaagtaaaa aacaaacaag ctacaattga tttattgaaa
    51121 ttgttcctgt agctcagtag gatagagcaa tcgcctccta agcgataggt cgctggttca
    51181 attccagtca ggaacgtata aataacccct gtatcctttg cggtacaggg gtttgttttg
    51241 tatttgtgcc aaaaatgtgc caaactagtt atcattttta tataaactat cgaacacagt
    51301 attgattttt tctttatcct gatcttcaag ctctcgaaca atatgaagat aagtagacat
    51361 tgtagtttct aaactgctat gtcctaaacg tttcgatacg ctaagtatat ttactccttg
    51421 ataaagtaaa atagatgcat gtgtatgcct tagtccatgc aaagtaaatt gcttttcaat
    51481 ccctaattct tttaattttt tgcgcaaata tttgctgacg gcgtttgatg aaactaatcc
    51541 attttttaag ttgaaaaaaa caaaattatg agggtttttg atttcaaaat tctcgaataa
    51601 ttctttttga ttgattttaa acttttttaa gagatcaatc gtatgtttat caatggaaat
    51661 tttcctattt gaagtttcgt tttttgtttt tccccattca tttaatttat aattccatgt
    51721 tttattaata gtgatgattt gatcttcgaa atcgatatct tcccatgtta atcctagaag
    51781 ttcagcaaat cgcattccag tggcaccagc aactaacacg agcataggag aagagtactg
    51841 cgcagaaagg ttttcttcta cgagtttcat taaagattta aattgatcat aatctaaata
    51901 tttatcttct tttggcttca atgaatcttt tcctttgatt actgcttttc tagttggatc
    51961 aaacggaatt aatccttctt ctacggcatc tttcaacgac gctctaatat ggttattaaa
    52021 cttaataacg gtagatttta catggtcttt agcatactta tttaaaaagc gttgatatcc
    52081 cactctatct aaatcagaaa tcaataccgc tggcatatat ttctttatgt tcattaacgt
    52141 atcttcgtat tttctataag tgataggaga tactgttcct tctttataaa gttgcatcca
    52201 atcctcaaag taatctgata ataatagatt tttgcgatcc cctttaaggc ctttgttcaa
    52261 gttatattct aattcgttgg cggcatcttt tgcttctcct tttgtcttaa atcctgattt
    52321 tcttatcttc gtgtattttc cgtcatcttt tttgtatgaa atttcgtatt gccaactatt
    52381 tccacgtttg actaatcttg ccataattga atcagctctc tttctctgat acaataggaa
    52441 ctataaagaa gcccattgtt tgggttttat tattttttgc acatcctttt tgcttgccgg
    52501 cgcaaggatg tgctatttgt cgttttaatg gtataattgg atgtgtatta gatcatccaa
    52561 tcagaggtgt ttattatgat taaagtgatt tttaaaagaa taactgaact tccagagttt
    52621 agattatttg ttgattattg gtatgtctgg ttttttattg ttgcattgct gataggtcta
    52681 gatgtcatat tagaaagaaa acttaagtaa gagttgagtt aataaattga attcctaaat
    52741 gagatatttt gtagcccata ttttgtttgc cgacatcacc taatactatg gagctaatcg
    52801 ttttttctaa cagaccaaaa tcagataatc tatttaagct accatctatt agctcttgtg
    52861 aatagccaga catgctgata tttccagtga aattttcgtt tccacgactc attaagcatg
    52921 ctaacaattg aatctcaatc gatgttaatt gattcagtac aagaagataa tactcctcgt
    52981 tatcccatga agcgctgtta attcgaagta aacaattctt ataaagattt ttatacatat
    53041 ctattttatt ttgtgccttt gatttttcta cctcgtcatt tatcccttcg aatattccaa
    53101 tgagttggtc cttgttctct aagttgaaaa catcttctgg aatttgatcg cgaatgtttt
    53161 ctaatgattc gtttaaattt ttgtagaatt tctcgatgcg tttgaaacgc ttctcgtttt
    53221 tagacccaaa ataaagtgac tgcacaacgc caccaatata aggaattgct ccaataccgc
    53281 cttcaactat taattcaaga tattcttttt tggttagttt ttcattgcta ttatccatag
    53341 ttacctccta ttttgtcatt tcctttacaa gcattgtgac tcctgatggc actcttttgt
    53401 ataggtttta ttattgtgca caatctaact cttagtgggg cgtggttcat ttatttttta
    53461 cttactttac tattaatcat atcccattga gcataggatt tttctatgtt cgatcctctt
    53521 gaactaattt ctcctgtaaa agttacttta tcgccctttg taaaggtatc agcattgttt
    53581 aagtccttcg caaaaattac atatgaaact ttaggtgttg cagaaatatc attccaactt
    53641 ttatcatcgt actctttgtc tgctataatg gctattctag tagtcattga ttcgataaca
    53701 gttccttcaa aagtatatgt tttaccacta atatatttag taaaagctgt attttgctca
    53761 gtagctggag taatagaata ataactatct aagaaagcac cccagtcatg attatttgtc
    53821 tctaaaaatt cttcaaattg agttaggctt ttattgctgc tgttagatgt agtagtttga
    53881 gtatcagatg atgagctttc ctgtttgtta ttgtcatttg cctcgtttga tgaggaaagc
    53941 gagaaaccta cggtagtaaa aataatcccg ataataagga gaatcatagg tgttttctta
    54001 tttgtttttt tgataaatct tacaattaac atgattaaac ctataataaa taaaacaata
    54061 ccagtaaaac caaatatacc gtccattaat agatcctctt tctcttttga tattgaatat
    54121 tataaaccaa gcaattcttt tttcttaaaa tcgaattctt cttgattaat aatcccttca
    54181 tctaacaact ctttatactt tttaatttca tctgcacttg aaatttgtgt ttctttggaa
    54241 ttattatcta atatagattg ttgcttctct atatattttt ttaaattttc catttcattc
    54301 caatattttt ttgtaaacat aacggtgttt tcatctttcg tggccgctaa tatacctccg
    54361 cgactttcgt ttccgcctag caaggtaaat tgtatataac cattactcat acctggtttt
    54421 tttaattgta cggctgatat atttttaaag gggatagttt tttctccttt aataccttga
    54481 ttaactaaat ttataaatcc ttttctaata attgaaatag aatcatcagt tactttaatc
    54541 aaggtttttc ctggagattt tattaaaatc tctttttcca ttttttcttc ctcatttctg
    54601 tgatatgatt ttttttgtag aagctcatat atgaggaaag agcccgtgtt gcagcacggg
    54661 cttttttaat gttttgctga aatcggtttt tttaataatt cttgatgtat tcatacatat
    54721 tgccttgcgt aagaatattt tttcttaaaa tagcattggc agacagcata acaagtgtat
    54781 ctgagcttat tctgaataga ataatactcc ataaattttt cgagattaaa ctgagattca
    54841 tcagtcagtt cgttctcaat atagatattt aataaaatta gaatagctat tttatctgct
    54901 tctgtttcaa attttgagtg aaaagttgta gaagtatcgt acaaaactga aaattcaaaa
    54961 tgagaggcgc tgaaatgtgc aagttcatga gataaatgaa aggcttctgc agtttcaccg
    55021 tatagatttt cattcaaaaa aatgattctg ggttttggat agtagaaacc aggctctttc
    55081 atctccatat aaactacttt caaattgtat tcgctcaaca tttctttcaa tttcaaatac
    55141 atacaaacca tcactccaac tattcatttt cctctaaagc tttagcaatt gcaatcgctt
    55201 tacgcattgt ctccttagat atttcttttc catcaaaaga aaaaacagta tcgtcttctg
    55261 ataaatccac atgtttaggg gtttctcttt cttctctacc tagaaggtag tctacagaga
    55321 catcgaaata gtcagcaatc cgacttaatt catctgaatt aggagtatta tttttccact
    55381 ttgctagata accgttagaa tatccaaaat taatttctaa ctgccgtata gatatctttt
    55441 tcctcttcgc caagtctttt attatttcat aggtattcat cgataaaaca acctttctaa
    55501 atgtttacaa aaaaagttta gaaaaatacg cagaaataat ttgactaatt ctgagtaatg
    55561 agctatacta tatcttgtaa acagatttaa caactaaaaa gacaacaaaa aacactattg
    55621 atatgtaaat gcagaccgcc aagaaagctt taaaatcaat gtttttatgt cttatttaat
    55681 tatgctctta gtatagagta ttactcagat actgtcaatt gaatttagaa aaaagttgtt
    55741 aaatttgttt acgaatataa aagaaaggaa tgagaaatat gaacacaccg caaattttta
    55801 atttcgaaca aaacgaagtt cggacaattt tagtaaatga tgaaccatat tttgtaggca
    55861 aagacgttgc gagtgttttg ggttattcaa acactaaaga tgctttgtcg cggcatgtag
    55921 atttggaaga taagatgggg tcgcgaatca cgacctcagg tcaatcaaga gagatgacaa
    55981 tcatcaacga atctggtttg tacagtttaa tcttaaaatc aaaacttccc tctgccaaaa
    56041 aatttaaacg ttgggtaaca agtgaagtgt tgccagcaat tagaaaacat ggaggttatc
    56101 taactccaga aaaagtagaa gaagctttgc ttaatccaga tacaatcatt caattagcaa
    56161 ctcaactaaa agaagaaaga actggaagat taatcgcaga acaaaagatt gcagagtacg
    56221 aacctaaaat ctcctattta gatagcatat tatcttctac agattcagta acaattagtc
    56281 agattgcagc agattatggg atgtctccac aacagatgaa taaattactt cataaactag
    56341 gtattcagaa aaaagtcggt aaccaatggt tattgtgcaa aaaacacatg aaccaaggat
    56401 acacaaaatc tcatacaact gagatcccga aagccgatgg tggcactaaa attgtaatga
    56461 ataccaaatg gacacagaaa gggcgtctat ttatctacga attactaaaa aaagaaggat
    56521 attaccctca aatggattta gaggaaattg gttagaaagg agttttagta tgactgacat
    56581 tgcagaaatc actcaacgag atagagaaaa aatcaaagaa tatgtcgaaa gttcaaagtt
    56641 cttaacttac accatgcttg ctgaaagatt tggaattagc aaaagctact tatctttaat
    56701 tttaaacggt aaaaagactt ctgcagaagc aaacagaatt atagattcga ttatcactat
    56761 gtacgaattg taaagggagg aacagctaat gcaatatcta gaagcaaaaa tcccaattcc
    56821 agaaggctat gtaattatct cccaagtgga ttatgaggag ttaaaaaaag ctgatgatac
    56881 tggtagatgg atgacgttgc cagaagtgct agaacggatt aacagaaaat atgattggtt
    56941 tacttctaga gttttaaaga acccaagata tagaaatatt atcgatatcg agaaaaacaa
    57001 aaatggattt gtctattatc cagttgaagg aagagacaca tatctatttt taagaagtaa
    57061 aacacttgaa tttttagaaa caaatttttc ggaaatctta aggaggcaag cggatgggaa
    57121 aatttaatag agcgctagtg ttcagcgcac cgctaatcat ctacgcttta ggactttggg
    57181 gaagcaggca agcgttgata ggaacgattg tttacatggt ttggattttt atggggcttg
    57241 atgaagctga agctgagtac agagcgaaaa agccaaccga gggggctgac taaaaatgaa
    57301 tagaaaagag aaactagaat gtatattact attactcagt ttaattcttt cactaatttc
    57361 tctattggga agtttgtatt tttgatatca acaattttgt ggatttgggt tctatttaga
    57421 gtaaatatca tttttgtttg gtgattaagg agtttattaa aattaatttt ccctacttca
    57481 aatgcaaggt aacaagatat agcactttta ggaggaatat ttagcggtac agcttcagag
    57541 tatattctat tatcatcgac tgatcctcct ttagcaatta atttcttaaa tggagtagct
    57601 gaccatctgc ggtttaagtt agcggatgaa agttctaaat taactaacat agctggttct
    57661 gttgaatagt tagaaatgat tacttttgta taaatcatat ctgcagcgaa gtaagaagca
    57721 ttaagttcaa cttctagttg agggcgcatt ccttttattt ttatccctgt taaaaacgta
    57781 ctcaatataa aacttattat tgacatccat tgaaaaattg ttaagtgaaa aaaattcaaa
    57841 ataaacacca ccagttttta actaaattat accaaaaagg agagaagaaa taatgcaaga
    57901 attagtaatt ttgaaaaata aagaagctgt gactacgagc ttacaagtgg cagaaagctt
    57961 cgagaaaaaa catcaacatg ttttaagaga tattgatgca ctaaaaaaag atgtgtccaa
    58021 ttttggacag atgtttgtag aaggtaatga accagattca tatggcagaa atcgacgagt
    58081 tttcttcatt agtagagatg gatttttctt gctggctatg gggtttacag gaaagaaagc
    58141 tatctacttc aaacaaaaat acattgaagc attcaacgaa atggaagatg ttattcgcaa
    58201 gaatactgtt cctcaaacaa ttgaagatat gatgatctat caattagaag aaatgaaaga
    58261 tgttaaaaaa gatgtttcca tgcttaaaga tactatgcga attagcggac aacaagagtt
    58321 tgaaattaag caaaaaggaa atatgaaagt tatgggagtt ctagggggaa aagaaagccg
    58381 agcttatgaa gaaatcagca aaaaagtatt ctcaaaattt tggtctgaat ttaaacgtac
    58441 cttttcaatc ccaagatatg gcgagttacc tcgtaagaga ttcgatgatg ctgtttcatt
    58501 tattgaaatg tggttgccag aaactgcgat ccgtatggaa attgatcaac tgaacagaca
    58561 acagagactt tttggtgatg acaatgaata gagctgaagc gctaagaata gggacggcaa
    58621 ttgctaattg ctggtggaaa tactataaac caatcatcct aagccaacaa catattgaca
    58681 agcaaaaagc atggcaacaa ataaaaaagt gactccgccg gcaagcaaag agtcacaaag
    58741 aaaacacatc ataaggagat tttagcatat ggaaaaagaa ctttccactc tagatcaata
    58801 tttgattgat cctgattggg gcaagccgaa aattgaggaa acaagtggtc gaaaaatcag
    58861 acgaaatctt ttgacgaatg aagaactagc ttgggatcaa gatgatttag gcaaccatgt
    58921 aactatttgg gatcatgttt atcttatcca tctatcgaag cattcgaata aacctgaata
    58981 tatttacgtc atcgaagatg gcttgattga tgcgctagaa gagtacgaca gagataactt
    59041 gattgatatc tcttattacg gaccaggtaa gaaatacatt gctgaaatgg aggcagaatt
    59101 tgatgagtga aatcaaaggg acaacgaact ttgaaaaact ttttagtcgt aagttaaata
    59161 aaattctcaa gaaaaaagga aattttgatt atttatcttg ggctcacgcg tgggagatta
    59221 tgaaaaagaa tgatccacag gcaacggtaa ctattaatga gtacaaacac tacagggttg
    59281 tttctggaac tcatcaagac tttcttgttg aggaatataa accttttctt atggatgaaa
    59341 ctgggactta tgtatctgtc tcagtaacgg ttaaaggaca cacggaaacc gaattatttc
    59401 ctgttttaga ttatcgaaac caaccagttg ttaaaccaaa tgcaatgcaa atcaataact
    59461 cattgaagcg atgctttgtg aaagcattgg ctctacacgg actgggatta tatgtatttc
    59521 aaggggaaga tattccaaca ccacctagaa tcgatacaaa gaaattaaac atgctagaga
    59581 cgattctaga agctttcaat gagcagatgg gtaaagatat gaccaaaacc ttaatcgaat
    59641 atgttaatga gcagacagat aaattagggc tcttagctga taacgttgaa actattgaac
    59701 agttaagcta tgagcaatgt gccttgatgg agcgagcaat agcagctaag agaaaagaat
    59761 tagataagaa gtgatatgag tgtttaaacc attaatcgat tcatattcag cggttctgaa
    59821 aaagttcaaa ggaaaagaca taagcgcaac catcaatgag gaagtgaaca ttgatcgact
    59881 aaagacgatg tatgacggct acgatggtga tcgagtcatt gaaattcgtt ttattgatcc
    59941 tagacgtttc accgtacagc aacgaaactt catctatgcg ctgataggcg atatttttat
    60001 cgatacaggc atgccaacgg acttctggaa ggaattcttc tactttcgtt ttgaaggtgt
    60061 cacagggcgc aaaataagcc tgaaagacga atcgaataca actgtgagtg atgccaatgt
    60121 cttagcaaat atcatcttag atttcatctt tgaacatcat attcctttca aagaaggcta
    60181 tgagatttta cctgcgaatc aagaatatta cttctacaaa tgcatcacaa aaagagtctg
    60241 ctgcatctgt ggcaaaacag gagctgacat cgatcacttt gacaaagcgc taggaagacg
    60301 aaagcgcaaa gaagttgatc atgcagagta cacatttgca gcactctgca gaatccatca
    60361 cacagagaag cacaaaatag gtgtgattaa tttcaaaaat aaatatcaaa tcaaagggat
    60421 caaattaaac cagaaaacaa tcaaaaagtt aaatattgga gggtaaaaat gacagaacat
    60481 cgaagttatt atgcgattat accagccaac gtaaggtacg acaaaagact taaaccaaat
    60541 actaagttgt tatacggaga gataacggcc ttgtgtaatg aaagaggctt ttgttgggca
    60601 ggcaatgagt actttgcaga tttatatggt gtgaataaag agaccatatc gcgatgggta
    60661 agtgatttga ttaagtttgg atacttgaat cgggaaatca tttacaaaga gggtaccaat
    60721 caaataatca ataggtacct acgaattaat caatacccta ttgacgaaaa acgcaatacc
    60781 cctattgacg aaaaagtcaa agataataat acatctatta ataatacatt taataataca
    60841 aaagaatata taagagagtt accgccttcg aaaaaatcga aggctaagcc cgtccgtcat
    60901 aaatacggag agtataaaaa tgttcttttg tcagatgagc agatggagaa actcaaaaca
    60961 gaattcccta atgattacca agagcgaatc gaacgactgt cagagtattg tgaatcatct
    61021 ggtaagactt ataaaaacta tttggcaact attcgaagtt gggcaaggaa agaaaaaagt
    61081 gaacctaaga acgcaagcag tggatacaag cgcacaggaa gacgagagaa gcttcctgaa
    61141 tgggcaatcg accaagaagc ctatctcaag aaaaaagcgc tagaacgagc taatagacaa
    61201 tcaaaagcac cattctaaga ggtggaaaaa tgaagatcga ttatctagaa ctaattaatg
    61261 aaatagcgaa ttataaaaag ggcgaagaat tagacgtcct gagagacgta tatgatcaac
    61321 tcgaagaagc tggaattgaa ggaattaaga atgatcgttc gagttggagt aaactcagat
    61381 actatttcgc actctatatc gatggaacgc aattaagaaa tttagcatat accaaattac
    61441 tattcattga ttgtgttaaa ggcttgcaaa aacatcttaa tgaacttgag caggtgtaaa
    61501 caagatggac ctaaagacat ttacagcaca gatcgaatta atgcatcaag aagctttaag
    61561 acaaagtgtg tcgtacgaag acaagtggct caacacattt catggcggac gtgagagcgc
    61621 acttgatcaa gtactcaaat tactgaaagg agaatgtcgg gatggataag aaagcggcaa
    61681 tgcagcgaat tatcgaattg acttattcag aagattggca ggaagataaa aaaatagttg
    61741 cagaagtcca aaagctcggt aaatcaatgt ggactgaaaa gcccaaacgg agaacgccga
    61801 gaaagattgc aatctggcat ggtgatcgaa ttctagtaac gggtaccgct aaacagttat
    61861 ctgaaattac tggtctgagc aaaaatatta tttgggatag agctaggagc ttatggattg
    61921 attcaaaagg aagacagttt aggtatgtgg aggagaaata atggacgaac taatcgcgaa
    61981 agtagagcag tgggcaaaag ataagggatt ggatcaagcg gatttcagca agcaaatgtt
    62041 aaaaacggtc gaagaaatcg gggaagttgc cgcttctcta gctagaaaag atgaacatgg
    62101 tttaagagac ggaattggcg atgtagtagt aaccttgatc atcttggcaa tgcaaaatga
    62161 tatggattta tacgagtgct tggattttgc ttatgacgaa atcaaaggtc ggactggaaa
    62221 gatggtcaat ggtgttttcg ttaagtccag tgacctgaaa taattccatt aatggaagaa
    62281 ataactgaat aggaggatag acatgattga tgcaaaacaa gtgcaaaaac agaaagatgg
    62341 aatgttgatg tttgaagcat atgttctacc atttcttaat caatttgaag ttttggaatg
    62401 ctctgccagc ggagaagaat tggagtatgt tgtaattcgt gaaaccaaag aaaacgttca
    62461 gaagctaaac gaatttcttt gcactattaa ctgttgggat atgatagctc caggattttt
    62521 atgtccagct atgggagaat ttttggaata ttgtcgtctt gaagatgcag gcactttgga
    62581 tttagcttat ctggtataca actacctaaa catcaacaca gatcatttgt ggtttggcac
    62641 tgccgaaaga aaatgggtag tccgctaacc accaatatca atgaaaaaag gcggtttcct
    62701 gaaagtggaa ttgccgccat tgctgtaagg ttctttacgc gactcaaggt cacagaaata
    62761 taaatgcaaa tctcttttga agtgatccaa agctctcgga aaatggaagt tttttgtttc
    62821 aaagaataaa tgagatttgc gtcaagaacc tgagagttat ttccaaaaaa gcttccaaag
    62881 aaccgaatga gctaaggaca tcatgtgtaa acacataata tagctctcct ttcacggcta
    62941 atcataacat gaaaaatatt cgatgtcagt aggaaaaaag gtgaattatg aaaagaatat
    63001 taaattatcc cggcagtaac agattctgca attaaactcc gaagctgatg tatcagtatc
    63061 aactgtagaa tattatgagc gtggagaaag tcaagcagtc acaaatgtaa aaatcgataa
    63121 cgtcaacggt cttatctgtt tagatgaagg cgatagtatg aatgaaattg ctgcagacca
    63181 tgaattatca gaaactgctt taattgatca aatcgaatta gctagacaat actttgttcc
    63241 atatgcagat acctggtcca agcataagaa tgacatcatt tttccagagg aacaatgaga
    63301 gcaactgatc cagtaattat ccttgaggaa gccaaattta tttggactca cgaagagata
    63361 gagcaagcac gcttgctctt ttctcaagga gttaagccga gcaaagtagc tgaaataatg
    63421 ggtcaaaaga ttcttgatgt cggattgctt ttgctccatc tagcagaaaa aaatttgatt
    63481 tgaggtgaaa atgatgattc aacttgcagg catccaaaca gggaaaattt atttttctgg
    63541 agaaagcaaa agcgaagcca accaatggct attgaaaact tacacgaaca ataagaagct
    63601 aaggaaaaaa tatcctgatt tgttgctaaa ggatgatcag attatgccgg aaccgatgat
    63661 tttgacccgt aaggagggaa gttgaaacta aaaaaccagc cgtgtgggct ggagttgcta
    63721 tttcttttta ataatgagtt tttctaaatt taattcattc tcacgagttt gcgtccaata
    63781 atcagaataa tattttaatt gtttaagagt aggaatgtcg tcttcggtaa aattagaaaa
    63841 taattctgga gaattatctt tttttaattg ttctaatcct gattctttaa aacgttgttc
    63901 aacgagtttt actaaattgt tgatattcat gataaatcac ctttttaaat ttaatttcga
    63961 tttgattaat cgatacaagt attatatcaa ataaaaaagc tgatttaggg ggtcttacaa
    64021 aaacactaaa attttttcaa aaagaggagg aacggtggtg aaagtcagag aacaattcaa
    64081 gatagtgagc gacgaagata atgtttacaa aataaagatc gttaatatta atgaatatcg
    64141 agaagcagat cacaaatatt tggttgactt atacatgaac gataaatatt tgggagaagg
    64201 attttgtgga gattcacttt ttgatgatga gcgaattttg aaggaggaaa cagaatgatc
    64261 cacgaactaa aaatactacc agaatatttt gaagcagtga cgagcggacg caaacaattc
    64321 gagatccgca agaatgatcg tgacttcaaa gttggtgatc agttaatact acgtgaatat
    64381 aaaaaataca ttaaacatga attacctgga ctaacgagac caacatttag ttacactggt
    64441 gactcataca aagcagagat cacttatatt actgattaca tgcagaagtc cggatatgta
    64501 gtgttgggga ttaaaggggt gaattaaatg aaagtataca tcttagctat cacagagggc
    64561 acatggatgt tcccagtcgg ttccggaaaa atctataaat caaaaacagc tgcttataaa
    64621 gcatttgaaa aatacaaaaa agaaaacggt ggcggcacta acgcaaagat tctagtggct
    64681 gataactggc atgaagaagg tgaacgtaat tgatttacct gttcattttc gtggtactaa
    64741 ctatttttat gctagtaatc ttattcaaaa aaagatgagt aaagacgaac gaaaaattct
    64801 ggccaacttt tatttagtat taaaaatcga acaaaatgtg ttttcggaaa ggagaattgt
    64861 atgggaaaaa caaaatcaaa gattaagaag aaaaaacgac gtttggaaca aaaggcaatc
    64921 cagaatggaa cggctaagaa aaaataaaaa agctacccct ttcgagatag cagcgcaata
    64981 ctattctacc ataaggggtg gcgtttgtga gatttcattg gttaaaagat taccaagaac
    65041 tagatgagca gattctttac ttaaagtgga atcttaataa aagtaagctt gaattgaatc
    65101 gatgggtctg tggtgattta gcaaacgtcc gcatcgaaaa gaattcgaga acttcttctt
    65161 tagaagagaa tatccaaaag atagaaaatg aattggaatt gttgatcgag caaaaagaag
    65221 aaatgttatt gctgatagat agcttttctg gtatcgataa tcaaattgtt aagatgaaat
    65281 atgttgatca aatgagctta gaagatattg ctgaatctgt tgggtatagc tcatcgtatg
    65341 tcagacagcg acatgcagaa attagaaaga cattgaactt tttagatgag tatgaacaca
    65401 gacaagctga ccgattgaaa aaagaaaacg aaattgattt ttacaatagc gagaagtaca
    65461 aagaacaact ctctttattc taaaattaca ctgttcacta aatgttcggt cattgtagct
    65521 atgtaaacat tgttagcagc atgatattct attagtgtca aaaaaatatg aaagagccaa
    65581 gatatcccaa ccgttttatt aattggtatc tgtggctctt ttattctttt aattagtagt
    65641 tggcataaag ttatttccat ttataaattg atcagctaaa tcagcatcat aatcagccgc
    65701 gataaattgc gctgctgatt taataaatgc atccatatca tgaacatctt tattagtatg
    65761 tctacgaaca tagtgcgttt catcattacc aatccaagta gcagctttgg ctaatctttg
    65821 gagtttagga aaatcattca aataattttc aattgtttta cctaataaca ttttttttat
    65881 tttatcttca tcctctgaat ttttagatat tgcataatct ttaattagaa attctagagc
    65941 ttttctataa ccaactccag caatttgttc caattgctca gatttagctt gtgtggcttg
    66001 agtataaata tcaacaaatg taggagaaac tttttcaata ttttctggta aatctatttt
    66061 aatcggcgga cggtaataat ctttaattaa aatattttca gaatatcctt catcttcatt
    66121 aaacgtattt ataaattgta aactataaaa tttgttgcac tcatcattta tacactgtac
    66181 taatacgcca aagattctat cattatcgaa cgcactatat gatgaaaccc caaaatacac
    66241 atacggagtc attatatttc cgcaatgcgg acaactattt ggcaaataaa ttgtctctgt
    66301 attttgacga tcacgatact taatattaac ttcttgaagc attaaaacac ctcgcatctt
    66361 ttttataaat cataccacaa aatatctgat aggagagtaa acaaatgaat gattttcatg
    66421 aagcggtact tagtattgaa gtagaatcaa gtttggctaa agtttataag aaagcaattg
    66481 aagcagagaa tagtccgtac agagaaaatt ggaatggtaa tcatgcacat gtgcaagtgg
    66541 agaatgatga ttacagaact ggaatgaata cgttagttat ttctttattg tcacacactc
    66601 tacccaatct gcaggaaacg attgaatggt atgagcgaat gggcgcaaaa gtaatccgta
    66661 caaattacaa aggagagaat taaaatggca atgatcaaaa ttagaacatc cattagtgga
    66721 acagagtatt gggattcaga aaagaaaagg acagtagttg ttccgaaaga tcaagaacca
    66781 aattttgaag taaaagaaga aaaaggaatt ttgagtgatg gcaaatcatt tgttgctgtc
    66841 aatggcgaac tcatagctca tagcagtgaa attcttgata gcgatggaaa cactgctgct
    66901 aattttgatg gagacgaagc tactaatgat cagtccactg aagatacgga tgaactggac
    66961 aatatgactg caaaagaatt gcgtgcatat gctaagaaac atggtattga tattcctggt
    67021 gctatccgtg caaaaggcga tatcataaat cttattcgtg aagtagaatg aaatactgtc
    67081 agtttgacgg atgcacgaac aaaatagcaa agggtatcta ctgtactgaa cacaagagat
    67141 caagcagatc acgcaagaag aagcagcaag caaagtctgt ttatcatcat gagaacaaac
    67201 cattctatcg aacgcaagca tggaaagata tgcgtcaatt tatttatgaa agagaaggtg
    67261 gtcattgtca gcggtgtggt cagttcatat ttggaaagag agcacacgtc catcacattg
    67321 taccaatcaa agacaacgaa ctgcttaagc ttgatccaaa caatctcatg ctattatgtt
    67381 caaaatgtca tccaattgtt gaaaacgaaa cggaagacaa aaaagttttt ccttcgtatt
    67441 tcaattgaag cccccctatt cattttcaaa attttttcgc gtggggagat agggtagcgg
    67501 ggagtcacgc gcatcgttag gtcaaatttt tcaaaaaaca aaggggggtg tatacaaaaa
    67561 tgacgactaa agcgcaacgt aaagcgatta ttgatgaaaa agtaagtgct gaaaaagctc
    67621 gtatcttaga aataatgaat ttgtctgatt tgtacaccat cactcttgat ccattaatcg
    67681 aatcatactt ggatattttt gaaatttacc aacacaaata tttattgtgg aaggaaaaag
    67741 gatttccgga gacgcaaaaa ttcacgaata aatcaggagc tactaatcaa tcaaaacatc
    67801 cattggcaca acaagtagaa acttgggcag ataagaagat gaaagctcta gatttattag
    67861 gattaacaaa caaagcaaaa actggtagac taattgctgg aggatcgacc gcaagaaaag
    67921 atgaagaaat tacacgccca gaagtaaagc cagtagatga actagcagcg cacagaaata
    67981 aatggcgtaa gaaggcaggt gctgaaaaat gattgaacct ggtgtaaatt atgctgattt
    68041 atttgcaaaa gaagtaagaa agaaacctaa gaagtatcct aagaccgttc gtttagcaat
    68101 agatcgctgg tatcagtgga aaaaaagaaa agatatttgg tttgatgtag atcgcgcgaa
    68161 tgaaatgatg gattgggtag aatcatttat tgttcacaca aaaggagaaa tggtgggaaa
    68221 accgtttctt ttagaaccct gggaaaaatt tatttattct tggatttatg gttgggttaa
    68281 agaaaatgaa aaaggccaaa ttgtacgcgt tactcgtgag gcttatgtcc agattccaaa
    68341 aaagaatggt aaaacattga ttgctgtcgg ttcattagga tatgcaatgt acggagaagg
    68401 ggcgttatca gttgattgct atgcttgcgc atctgatttt gctcaagcgc aatatgctgc
    68461 caaacctttt gcagttacaa tcttaaacaa tccaatccta cttgaaggaa ctaaaatatt
    68521 tagggggcca aagggaactg tttctagtat tacttatgac tatattcatg aagatatggc
    68581 ttactcaaat aaatttattg ttcaaaccaa gaatattgat aatatcgagg gatccaatcc
    68641 atattttgta ttgaacgatg aattgcataa acaggagaaa atggaacagt atgacaattt
    68701 taagtctgct cagatatctt taccacagcc attgatgttt aatatctcaa ctgctgggaa
    68761 aggttcgtcg tctgttggaa tgcgtgtata tcgcgaagca aaagaagtgt tgaaacgtga
    68821 tgataatgat tcaaactttg ttctaatcta tgagccaaat aaaaattatg attggacgga
    68881 tagaaaagtc tgggaaatgt gcaatcctaa ctggggaata tcagtcgatt tatctgcttt
    68941 agaatcggca tttaaaacag cgcaacggtc agctcattcc aaagctgaat ttctaacgaa
    69001 acacttggat gtatttgtga acggcgcgga taatttcttt gaacaggatc aagtagagcc
    69061 atgtttagtt accacacaag aacttggtga tttaagtggc gaaccatgtt atatcggttt
    69121 agatttatca cgtacacgag atttgacctg tgtatcttta aacttcccaa catgggatga
    69181 agatggtaaa gcggttctta aagtaaagca actttatttt attccgaatg aagatttaga
    69241 gtttcgagaa aaagaagata atgttcctta cagtgatttg gctgaacaag gtttcgttga
    69301 attttgcgac ggaaaaatga ttgatcaaga tcagattttg cagtacatag aggactgcat
    69361 gaatttatat gatattcagc aagtgaatta tgatccagcg atgagtgaca aacttgttga
    69421 gaaattagaa aacttaggat tggaatgcgt tgaagttgct caatatccta aagtattgaa
    69481 tgctcctttt gacgatgtcg aacggttgtt ttatgagaaa cgaattcaat ttgataatcc
    69541 attattcctt tattgcactt tgaacgttgt agcaattact aacatcaatg gacaaaaagc
    69601 gccaagtaaa cgtcaatcaa agaaaaagat tgatgggttc gtggcgtttt tgtgtggtca
    69661 taaggaaacg atgaatcaaa tgacagatat tgattcagat gagttagatg attacctaag
    69721 ttccatctat agataaatag aaaggcggtg aaaaaaattg aaattacgtg atcggttatc
    69781 gaatgcagtc tattctttta tggaaaaacg tggatatatc gaggatattt ttggacacta
    69841 cacacgttat ggtcaaagat atgtgacgga ttcatctatc atggaatctt ctgatgttta
    69901 tgaattagtt caagacatat ctaatcaggt ggcattggcc acaccaattg ttattggtcc
    69961 cgacggcaac gaagtcaaag atcatcactt actaaatatt ttgaagagtc ccaatgatta
    70021 tttgacagga ttcgaattta ccaaattgga aacaaatact ttattgatca atggtgagac
    70081 attcccatta acggataggg atcagcttca tttggcgtac ggtgtaacaa ctaaaatcaa
    70141 tgaacgactt caagaagaat ttgaaatgaa tggtcaaaaa atacctggtc aaatgattcg
    70201 acacattaag aacatcggaa ctgattcatt aaaaggtgct ggaataattg atcttgcaag
    70261 aaacactcta gaaggcgttc tgagcgctga aaaagttttg acggacaaat atactaaagg
    70321 cggtttactt gcgttcatgc ttaaactaga cgcccacatc aatccaaata atagcgccca
    70381 aacaaaaatt gtcaaagcta tattggatca actggaagga acgcaaaatg agagtgatca
    70441 ttctgttaag atgattcctt tgggaaaagg atattccatc gagacattaa aaagtcctgt
    70501 tgatgacgcg gcaattttga attatttagg tgtttacaaa aaagacttag gaaaatttct
    70561 aggaatcaat gttgatacgt atcaatcgct gatgaagaca gatattgaaa aagcgatgat
    70621 gtatctgcac aacaaagcaa tcaaaccaat attgaaaaac aagagcgaac attacaccgc
    70681 tctttttttt atgcctaatt ctggctatag agtggaatgg aaaattaata ttttggattt
    70741 tgttccttac tcaacaaaaa caaatattgg ctacaacatc gttcgtaccg ggattacaag
    70801 tccagataac gtggcagaaa tgcttggttt tcctaaacag aatactccag aaacacaagc
    70861 tatctatatt tcaaatgact tatctaggat tggccagaaa aatgcaacag atgattcctt
    70921 accaacgaat gatcaagact tgaaaggagg tgatggaaat gaagaagaag gaaattcgca
    70981 cgattgacat caccaatctt tcaacacgtt ccgatgaaga aactcatacg aggaccatta
    71041 gcggctacgc tgctgtattc aacagtcaaa cacttttatg ggatgactta agcgaagtga
    71101 ttgttcctgg tgcattctca aaggcaatta gtaattcgga tgttcgttgt ttgttcaatc
    71161 acgattggtc caatgtgcta ggacgtacta aaagcggaac ccttcgcctt gaagaagatg
    71221 aacgtggttt gaaattcgaa gttgatttac cggacacaac ggtagcaagg gacttagtta
    71281 aatctatgga acgaggagac atcaaccaat gtagttttgg ttttgtgccg actgaagaaa
    71341 cgtgggacta caattctgaa ccaatgcttc gaacaatcca tgaagtggaa ttatacgagg
    71401 tttctattgt gcctttgcca gcatacgaag atacagaagc tgcattaaga agtcgtgatg
    71461 aattagaaaa aaacgtcgaa gaaagaaaaa aattaatcaa aaaaattaat caagcgctag
    71521 aagcgtagga ggaaaaatac atggataaag aattattgaa aaaaatgaag gcacgtcgtg
    71581 agcaacgatt gactgaatta cgtgaaaaag ttgaatcagg agaattacgc gaagcagatt
    71641 tagaagccgt gaaagaagaa attgacagtg ttattgatga attgaacgga attaaagacg
    71701 aattaggcgc agattctgga actgatgaaa cagacgacaa tacagatgat caatcgaata
    71761 gtacggattc agacgaaagc cgttctggtg aagacaacga tcaagaagaa gattcagaca
    71821 gtgaagatag ttcagaaaat cgttctggaa tgattactca acagcaacga gatggattac
    71881 ttggatcaat taagaacgga ttggaggcac gtgcaaaaat gaccaagaaa caaaaagatc
    71941 aacaactacg aaaagcattt gctaattttg tagctggaaa tatttctgaa gcagaagctc
    72001 gagctttagg gattgaagct ggcaacggtt cagttactgt cccagaagta attgcatctg
    72061 aagttattac ttatgctcaa gaagaaaatt tacttcgtaa atacggaaca gtggtgcgaa
    72121 catcaggaga tgtcaaatat ccaattcttg tgaagaaagc agatgcgaat gtaaacaaga
    72181 aagagcgttc aactgatatt gctgaaacag ctattcagtt tgatgaaatt ttgcttaatc
    72241 ctgccgaatt cgatgctttg gcaacagtaa ctaaaaaatt attaaaaatg tctggtgttc
    72301 cagttgaaga tattgttgtg gaagaattga aaaaagctta tgtgcgtaaa gaaatcaatt
    72361 atatgttcaa tggtgatgac gctggaaatg aaaatcctgg tgcattagcc aaaaaggctg
    72421 tagcatttaa aaaaccttta gatctaactg cttcaggtgc tgggcaaaaa ttatatgatg
    72481 cattaatcga atttaaaaat acaccagtga cagaagtgat gaaaaaggga cgctttatta
    72541 ttaatcgagc tgctttgact gccattgaaa aaatgaaaac agatgatgga tttcctttgt
    72601 tgcggccatt cacacaagca gaaggtggaa ttggttacca attagttggc tatcctgtgg
    72661 attggacaga tgcagcagat aaaaagggtg aaccagacac gccagtttta tattttggcg
    72721 atttttctgc atttaaaatt caagaagtta ttggtgcctt ggaaattcaa aaacttgttg
    72781 aaaaattctc tggtaaaaat caaattggat tccaaattta caacttgcta gatggtcaat
    72841 tggtttattc tccatttgaa ccggcagtat atcgctacga aattacaaaa ccagttggtg
    72901 gttaagatgg aagagcaaac taaagaattg tctttagagg aaaaattcaa atcacatatt
    72961 cattttgaag agggcatgga tgattctttg ctctcttttt atttaaatat ggcaaaagat
    73021 tatgtcaaaa cagcaactgg tggccaacaa gaatatctta ttttgatggt tgccggcatt
    73081 gcctatgaat atagagtttc agaggatgaa ctcgacaaag ctatgaatgc catgacgcca
    73141 tttatcgtgc aaggagcgat tcaaaatgcc gaagagacag accaataatc tcagatggaa
    73201 agccgaattg ctagacatca aaacaggaac agacggaaac gatcgtccaa ctacaattta
    73261 cgaatttaag cgtctaatat tctatgaaga actcggtgtg acttctcaag aaaaatattt
    73321 atcacagcaa gccaagacag acgttgtcag acgaattaaa gtcagatggg ataaatccat
    73381 cacagagaaa ttaagtgcgc tcaaaattga ttctgtaacg tataacatta ctcgcattta
    73441 tacgaatccc gatgcaagag aaatggagtt gagtttagct tatgtcgatt agctttgatg
    73501 aattgaaaac agcgctgaaa tcaacaaagt tagcagtgtt cagagacaaa gccagattag
    73561 ggacgatgta tccatacatt gtgtactcaa atgtgagtaa cagcaaaaaa atggcatccg
    73621 gtaaagtcta taaaaaatta ccttattacc aagtctcttt ttttacactt ggaacagaac
    73681 aggatttagt tgttattgaa caagcgctgc aaaatgctgg cattccatat tcagatttta
    73741 caggtataca aggtgatgag aacgacgata ccgtaaccaa ctattacaca tatgtgaggt
    73801 gtgtggaaaa tgccaagtaa taagaatggt ttttctgaaa tatcggatta tttaggaaac
    73861 ctttcaaaag ttgatccgaa aaaattatcg ttggaatctt tagaagaagc agctaacttt
    73921 tatctaaagc agttgcttcc taatattcct aagtcgctct taaaaaagaa acatatgcgc
    73981 gatcaaataa aagtagtagt tgaaaacgat caagtgaaag ttcaatttga agagacggcc
    74041 ttttactggc gctttgccga aaatggcaca acaaatcaac gtgcccaaca ttttgcaagt
    74101 ggtacgtatg aacaaaacaa agaaaaaatt gaagaaatta tgactagaaa aatacttgat
    74161 ttatgggaag ggtgatttta attgggaaaa caagatactt tttattttga aggattggac
    74221 gacattttaa ttgcgatgat ggcaacgcca gattctgttg gaactgcacc gacttatagt
    74281 gaagttttac gattgccaat tgccacaaaa atcggtgtca aagggaatgg aacagcatta
    74341 gaaaaatggg catccagcaa aatgtttcgt cgtgtgtcgc gagaaacaaa acatgaactt
    74401 gcgttggatc acgtgggtat tccgatagaa gtgatggatg aaatcaaagg attagttgct
    74461 aaaagcggag taacgtttag caaaaatacc gcacgagaat ttccgtactt cgcctttgga
    74521 tttattggaa atattgaaaa tggcggtaaa aaagcagttt ggtatcctaa tacacaacta
    74581 tccaatgtga ttgacgaaga gtatgccact gcagaggaag aaacaaaaat tgacgatgta
    74641 actgcaaatc tggtttccat cggactgaaa tacaataatg tgatgtatgc aagttttgat
    74701 tcaaatagag acggagcttc tctagaatta tttaataaat tcattgctca acctgtatac
    74761 gatgaagaac agtggaaaac attggctaaa gttggaggtg cgggttaatg gctcggttat
    74821 ctgattatgg aattcacgtt gaagacttaa aaaattctgc tgttgtaatt attcaaggcg
    74881 cagaattccc tatttcattt actatgcaaa cgatggaatt tatagcagat gtgtatggtg
    74941 gagattattc gcaatttgaa tctgatatga acgccatgct atctaaaaaa gaaggacaaa
    75001 tttcttctgc taacttatcg cctagtgatc taaaaatcat gcgtgccttg atttatgcca
    75061 tgctgcgtac tggtggttta gaggaagatc cagaaactat tttcaaattt ttgggaatga
    75121 gtggagaggt gttgtctgct tatagtacct gtatggaaat ttttgctagc cagacatttc
    75181 aggtggaaga cctaaaaaaa tccaagaagc cacaagactt tcaaaaagcg caagcaaaaa
    75241 gaaagaaaaa caaaaagaat cggaagagat aggaactcct tggagttttt atatttacgt
    75301 tgctctcact ctattgaatt ggagtgagag tttcttttta aagtctacac ctaacttgtg
    75361 gctcaaatct tatttacagt ggttacaaca aaacaccgat tttgaaccac ctcaatctgt
    75421 aactatggat aaatcgcctt ggtggtagaa aggagcgcta agataaatgg ctggtaaaga
    75481 atctgatgtc gttcttaatt ttaaaacgaa tggcgaagtc agttattcga aaacaatcaa
    75541 agaaatcaac aaagaaatga acttagccgc tgccgagtac aaaaaccaag tgtctgcgat
    75601 ggacaaggat gcaactcaaa cagaaaaatt gcgagcggct aaacaaaaat tagaaaaaca
    75661 attaggattg gctgaacaac gatctcaaat gctgagagag gaatatgaaa aatctgtcaa
    75721 agaaaccggt gaatattctg ctgaatcaga aaaactttat aaacaattac tcaattctga
    75781 aaccggagaa aataaacttc gtacagcatt agaacagacg aacgatgcac ttaaagaaca
    75841 aggtgacgtt tctgttgata cagcaaaaaa actccagaaa atcgaagaaa caggtgagaa
    75901 agtaaaaggc gttggtgaaa aaatgtctgt tggagtaacc gcgcctattg tagcggcagg
    75961 agcagcagga cttgcagcat ttggtgaagt tgacgaggca cttgatacca tcattacaaa
    76021 aaccggagca acaggtgatc aagctgatag actttcacag tctttcaaaa acgttggttc
    76081 aaatactcat ttacctttac aaacggttgg ggaagctatt ggtgaggtaa atacacaatt
    76141 tggattcatg gataaaaaac tggaagattc aaccaattat ctcctacagt acgctgaaat
    76201 caatgataca gatgtttcgc aatcagcaat atctgctcga caagctattg atgcttatgg
    76261 actagaatat gatgatttga attctgtcct tgatgtaaca acgaaaacat cgcagaatac
    76321 tggtcaatct gtagacgact tgatgcaaaa agcaattgat ggcgcaccac aaattaaaca
    76381 attagggttg agctttggtg aaggggtcac tttacttgga caatttgagc aatctggtgt
    76441 tgattcaagc gcagctttaa gtagtttatc taaagcaaca gtggcttatg cgaaagacgg
    76501 aaaatcttta agtcaaggac tagaagaact acaagacaag gtaaaaaatg caggttctga
    76561 aacagaagcc atcaatgcag cagcagaagt attcgggact aaaggcggtc ctagaatggc
    76621 cgatgcaatt cgtagaggta ctttgaacct ggaagattta gcaaaaactg ctggagaaag
    76681 tgggggagct gtaggagaca cattcgatgc tactctcgac ccaattgatc aagccgatca
    76741 agctatgaac aatgcaaaat tagcaatggc tgacgtaggt gaagcagtcc aagtaagcct
    76801 tttgcctttt tttgaaaaag caacttcctt attacaggaa ttctctaaat ggtgggggtc
    76861 tctagatcaa gatacaaaga attggatcat aacaattgct ggtatagcgg cagcagttgg
    76921 accagtacta atcgttcttg gttcacttat gggatctgtt acaaaaatcg ttggggaagt
    76981 taaaagtttt ataggagttt ggcaaggact tgctggttta tttggaatgt cgggaggctg
    77041 gtttgcatta gcagttatag ctattggcgc attagttact ggactaattt gggcatataa
    77101 taacgttaaa tggtttcatg atggagtgaa ttctttcttc aaaggtgttt cagatgtagc
    77161 tgttgaaata tttaattttt taagtggtta ttttggtgga tttttcgatg gtgttatagc
    77221 aaatttcaat aatttttata atgctggaaa acgaattttc agtggttttc tagattttat
    77281 cactggagta tttacaggga attggtcaaa agcatggcaa ggtctagttg atatttttgg
    77341 aggtattttc gatggtattg ttgctgtagg gaaagctcct attaatgcca tgattggatt
    77401 gatcaatgga tttattggtg gattgaataa tataaagata ccaaaatggg ttcctggtgt
    77461 aggtggaaaa tcattttcta tttcaaaact gccttattta gcacaaggcg gtcatctaat
    77521 caatggacaa gcgattgttg gtgaagctgg acctgagtta ctgactgcca agaatggtaa
    77581 aaccacagtt actccattat cagacgaaga aaaacgcaaa gggatcagtg gaagagtttc
    77641 tggaggtagc attgaacagc atatacacat tggcaaagtc gatgcaaaca atccatctga
    77701 gttagatcgt atgaatcgta aatttgctaa agcaaacaaa caggctattc gtgatttggg
    77761 aggtgttcct atttgagtcg acaatttatg aatccagatg aaccaaattt tatttggaaa
    77821 aatcggaatg cagtaattga tatgaattgc atcattgagg cagagcttcc agatattatg
    77881 ccgaacaagc gatacgaaac ttacacgatt cagggccgaa gcggagaatt gacggagacg
    77941 tttgatgact atgaaccttt tgatttggaa atagaaggga tcactattcc acattcgaaa
    78001 ctgagagaag tcaaacgatg gctcactggt aaaagccaat taatcacaca taatgatcca
    78061 gacaagtatc tagaggctat ctgcagcatg gataaagaag tccctttcga aaacgagtgg
    78121 ggcttctttt atacattcga tgttactttt cgttgtcagc cactcaaaag aaaaatcggt
    78181 gaagcaccta aaatttttca ttctagtgtt atggatattt ttgatcatgg tgacgaaatt
    78241 gcacatccct atctggaaat agaatcgaac ggaggagata taacgatcgc tgtcggtgat
    78301 aaaagcctaa caatacttaa tacgttagct gcaacaatcg tggttgatac tcagcttgga
    78361 aaagcaatac aagaaggttt gaatttattt acgcgtggtg attggccagt attgcagcct
    78421 gaatggaatc aggtaaaaat atccggaaaa tttaaagaag tgcggttttg gaataggagt
    78481 gtgtatctgt gacgcaagaa tttatttatg cttataaaaa aatgccagat gatttgagcg
    78541 tgaacggagc gtcgttagtt gattgggaag atttgccaga aatcaatcgt gtgctgaatg
    78601 gccaatatcg tttttatggt aactattcaa gaagcggaca gtatcgctct tatttaaaaa
    78661 aaggaaattt tataaaagcg aaggtaccag atggatcatg gcaatatttt gaaatttata
    78721 atgtcaaaaa gaatttgacc tccgtttctg taacagctcg gcatattggt tttatggcca
    78781 ataagaactt tattgtcaag tcgtttacgg ataacggcaa tgggtctcag atcatgacca
    78841 atcttaaaaa cagtttggca tttgatcaaa aatttaacta tctttcgaat gtagggacaa
    78901 cgcaccaatt tacagcaaga caagtcgcgc cagttgaagc aatcattggt tcaaataacg
    78961 gtaatcaaaa tttgactggc gtgactagcg cggaacttga tatggataac tatgatttga
    79021 aactggtaaa acagattgga tcagataatg gttttcggat tgattttggc atcaatttag
    79081 aagcaatcga agaagaaatt gatgaagaat caattgtcaa tagtttgtat ttggttggcg
    79141 gtgttcctga taacgattat gatgaagaca aagaacctat cgaatatggt tatttagaaa
    79201 ttgatggagt aaccaacgag aatcgacgta ttgccaaacg tgaaaacgga gattgtaaaa
    79261 cagttgatga attgatcaaa tggggcaaaa ccttatttga caatgatcgt atccatgagc
    79321 caaaagctac tcatacagtc agtatggtgg cgttggaaca cacactcgaa tacggtgaca
    79381 tgtatcaaga gctagcgtct ttacactttg gtgatgtcgc tcatgttagg gcgaaagagc
    79441 tagatatcga gataaaagag cgtatggtcg aatacactta tttcccaacg cttgggaaat
    79501 ataaggatat tgttttaggt aatgatttat cactgtacac ttcggcagta aatactcaag
    79561 cacaagaatt gaaaaagaaa atcgacaatc gaacagaaac gttagttcaa aatgtgttga
    79621 atgcgacggc atggatcact ggtaattctg gtgggcatgt cgtttttcgt ccagaaaaag
    79681 ctccatcaga gattcttatc atggatactc caaatgtggc gaatgcaaag cgagtgtggc
    79741 gttggaattt aaatggctta ggttattcag acaacggagt aaatggcccg ttcggtattg
    79801 ctatcacatc aaaaggagaa attgttgctg acttcatcaa agtaggaaca ataaatgcag
    79861 aagtattcga aacttccttt aatgcttatg gtgatgtgtt aaaacttgta aaaggcacgc
    79921 ttcaaatttg gaatgaaaac aaaaaaatca tggagctaac caaaaaaggt atggaattct
    79981 ggaatagaaa agaatccatt ggaacgatcg gaacaacaga ttcagcagga aatccatttc
    80041 caaatgctgt aacacctaca cctcttgagg aaaattcttt ggtaatacgt acaaatggcg
    80101 atggaaaata cattttaatt tctccaactg cagaaaaagg atttgtgtta ttaggaaacg
    80161 gaaaagcata ttatttcggt gatttagata ttcagggaaa acttactgtt agaggtaaag
    80221 aagtgatacc aggacaaaat ggcggtccat ctggcggagg agaaacacct ggtgggtatc
    80281 ctgatgaatt aaaaacagat gcagaaaaga gagcttggag aatatacgat attttgtgta
    80341 ataacggatt tacgaaacaa tctgcatgtg gaatattggg gaacattcaa caagaaacag
    80401 gaggaacttt tgatcctgat actgttcaaa taggtggacc agcatacgga ttagttcagt
    80461 gggatggttc ttcatatcct cttgttggtc cagcaacatg ggatggaaaa gtttatgttc
    80521 aaaacttatt taatgctgca ggtattaaag aaccaataac gagcttagat gcacaagttc
    80581 gattgcttat ttggacattt acaaatggac aatggatggg cgtagtacaa cctacgacgg
    80641 ttgatggatt taaggcctgt actgatccaa gacaagcagc atatgctttt gaacgaaact
    80701 atgaacgtcc ggcagcgaca catcctgaac gtcaagatta tgcagttaac tggtataaca
    80761 aatttaaaga tttaaaacca ggaggagcta ctggagaagc aggactaaaa catttagagt
    80821 ctttgattgg acaacgaatt ggcaatggtc agtgttatgg cttgtctgca gaatattcag
    80881 gatatctggg tggttgtggc atgggtgctg gaacaaaata tggtttaact catgtgatag
    80941 gaaatacttc tgcagcatct gatattggta ttgcctatga ttggtctgct gttggttgga
    81001 aagtgattca aaaccctaga tatgatcaat tagtagttgg tgcaattatt aattgggcaa
    81061 gaggtggaca agtgggttca tggtttgcag acggaactta tggacatact ggcgttatcc
    81121 gaggcttagc taatggtcgt atgcaaactt atgaacaaaa cacagagtta ggtatgattt
    81181 gtggaaagtt agatcgccag tattatagtg caagtgcaat ttcttccatt gtcataccac
    81241 caaaataggg aggtgattta atggcaaagt ggaatgtcat attaagtaca acagaaccct
    81301 ataattacgt ggggatgatt caagttcgac aaggcaataa aaacactgaa gttatggaag
    81361 ctacaattgt cgaaaatggt cttccatatg atttatcaga atgtaaggta tattttgaat
    81421 cagttgttgg cggaaaatat ccagtccaat tagaaacaag aattgtggat gctaaaaaag
    81481 ggaaaatcaa atatattttt gataaatatt ccatgcagtg tttgcatcga caaacagcca
    81541 atttcattat atttaaagga gaagacttga ttggaacaac tcaagacttc tcctattttg
    81601 tcatcaatgc tgtttcaaaa acagaaggag aaatgggttc ttattggcaa tcaattgaag
    81661 atttaattgc tgatatgaca gattttatta atgaaaataa aggcgatttt acggactgga
    81721 tgaatgaaag gaaagaagaa tttgatcgct ggagagaaga acaggagaat agtttccaag
    81781 attggagaga aggacaagaa tcagattatt tgtcatggtt tgaatcaatc aaggatattt
    81841 tgaagtctat cgatccaggt ggagtaatgt tagccgaatt aatggatgca cgtgtagatc
    81901 ttcaaggtgt acgccatgaa tcgatttctg aacgtttcct atccgatcta aattatttgt
    81961 atcaaaaaat gaaagcagca cttttcacga ttgaatacgg tgaaattgaa gtgactgata
    82021 ttcttcaaga cgatctcttt tcagataatc acgaagtcga aaaaattgaa ac
//
LOCUS       DAFEKH010000004        78017 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.004, whole genome shotgun sequence.
ACCESSION   DAFEKH010000004
VERSION     DAFEKH010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 78017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 78017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..78017
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.004"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(980..1153)
                     /locus_tag="LP386_000293"
     CDS             complement(980..1153)
                     /locus_tag="LP386_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917564.1"
                     /translation="MSMLVRKLPLSVREFLFYLVCLIASGFKLIEHIFIFAYLLAMIA
                     FLSGGWLIIYLLS"
     gene            complement(1156..1554)
                     /locus_tag="LP386_000294"
     CDS             complement(1156..1554)
                     /locus_tag="LP386_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917565.1"
                     /translation="MRLRRNKNYTTIILEDFTDQELLIVGKTKADFIEKGNASIVKAS
                     KVAVEKYFDSLEESAKEIFNGEKAGSYELDGIKFSLIPTTENIIPKKLYYIFSSEKHT
                     SMKPCIFDWQWLIDAVLDVKCSKYNITLGC"
     gene            1770..2825
                     /locus_tag="LP386_000295"
     CDS             1770..2825
                     /locus_tag="LP386_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParM/StbA family protein"
                     /protein_id="HBL1917566.1"
                     /translation="MKEPLLFSVDLGNKSVKEMSTHVSPLSLPSRILNKNIINSGRFS
                     NIGSSLKRSLNVSEYSLVNTTESYYFGKDIHELGKDDYVIESLGFGISRYKQETYQNI
                     LSFSLANLARLEDQSDDVLTVNLVLGLPSSDYTETIVKYVMQQATRQHSVEVDGKAYN
                     INVDTVWVLPQPIGTLYNLLLADDGSVQDESLISQKIGFVDIGGGTKLFDVVQNFEID
                     ENNREQKDTGIFTLYNRIVNMLDLPISPNAFQLEKIIREGKEKGVYLFKPSGNESFDI
                     SEVVEREIKTYTNMVVAEVLATFKNFTTLDKVVFTGGGASIIDKQLVKDKIPHTLFVE
                     DSEFSNVKGFYKFGLTQ"
     gene            2845..3198
                     /locus_tag="LP386_000296"
     CDS             2845..3198
                     /locus_tag="LP386_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917567.1"
                     /translation="MNKGKSERYVVIINREKVSELPLAEFLESEYETLGVKYSQTIKK
                     ALNLYRRVKNNEVTIIEAGNDINDSKVAEVKNKPTDHNPIQQEHPSTVTSDHSAKKEK
                     PMLKGFNAPSNKDLL"
     gene            complement(3380..3676)
                     /locus_tag="LP386_000297"
     CDS             complement(3380..3676)
                     /locus_tag="LP386_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917568.1"
                     /translation="MIEVKENRFKKFAEAEVEEVPEVVEAVEEPKQTLKETTSSLVAK
                     LKSDSSEKKKNYQFTLQPSQRKKLSKISEKLGIRSDSALLGEMIDNLYDEVFGE"
     gene            complement(3680..4498)
                     /locus_tag="LP386_000298"
     CDS             complement(3680..4498)
                     /locus_tag="LP386_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL1917569.1"
                     /translation="MEKKLSIITGNIEKGGTGKTTTIYNLGGYAVENLGMKVLYIDED
                     KSQNLSKRFPDAFSKAKRENTINHLYLHGSAEPLAINENMDILVAGEDLKQVEMQMRD
                     MPNNRTLLFRWIVVNYEQLKEKYDLILIDTHNDAGLLAQNAWAVSDLVVGISDPSKDG
                     FEALLKLGKDIDSLAKQLIDIKTGETLMETKYATIGSRIKHNTNSSREFLELVPTLSN
                     YLGYVQEKELLNATSLEGKNIAEFAKDKNIYRKNKDFFESTFTLYNKIIDTAQE"
     gene            4718..4939
                     /locus_tag="LP386_000299"
     CDS             4718..4939
                     /locus_tag="LP386_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HBL1917570.1"
                     /translation="MPVISIRVSKEEKDFLEKVAEFNGDNISEFMRSNSLQTAETLVD
                     FATYKQLMKEHEENDQSISHEDMLKELGL"
     gene            4941..5207
                     /locus_tag="LP386_000300"
     CDS             4941..5207
                     /locus_tag="LP386_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBL1917571.1"
                     /translation="MTYQVRYEREAQKALKKMDKFQAKVILNWIEKNLVGTDDPRKHG
                     KGLTANKSGYWRYRVGAYRIIADISEHEVTILILSIGHRSEVYK"
     gene            5320..5859
                     /locus_tag="LP386_000301"
     CDS             5320..5859
                     /locus_tag="LP386_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917572.1"
                     /translation="MYNISVNKLINFQKERFFMGWYGDYSSANEVIEEKKGYAKNGLE
                     IVDTKVTKTYGIILFKDAEGTYDIDSFIFRDEMYKPIYFLNDSPAYFKKIPKKWLKFF
                     VGDQEKMVKRQLDRIKEESNKPKLDDLLVAGKTYSIWDGSYVAVYQYKLKRSFIFRLQ
                     DGSLTRFTRLPAGDVKEVA"
     gene            6065..6247
                     /locus_tag="LP386_000302"
     CDS             6065..6247
                     /locus_tag="LP386_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBL1917573.1"
                     /translation="MINLFLLVTASTLFFTGISLIISYLIYKKAENHTSKATGLAVSS
                     FLTLLTLFVTLSFSFV"
     gene            6350..6634
                     /locus_tag="LP386_000303"
     CDS             6350..6634
                     /locus_tag="LP386_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917574.1"
                     /translation="MLTATLQQPTHVAIAESYTINAGIVKQLIKDREFKKFNSRQAYN
                     RQLKKAILKHKDSFIGNLESVDVKTVSTAFSVVEVTIDGRLISLFAFGIN"
     gene            6641..6886
                     /locus_tag="LP386_000304"
     CDS             6641..6886
                     /locus_tag="LP386_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917575.1"
                     /translation="MWTLEGKSFAEIWTEFIEVPTRIDPITSEKVLDADFYNLKAGTS
                     LECVWMYLEEHFKGVTLGHVLYHNGAEWDAIGNIHFS"
     gene            6908..7162
                     /locus_tag="LP386_000305"
     CDS             6908..7162
                     /locus_tag="LP386_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917576.1"
                     /translation="MNYTDEEQITLEYVFIDEEGEEIEKVLIISSKDLENALTYEPYE
                     STVTVNEFLDTYTSDDTWEIMNICNANNIQFAEKNNKSFY"
     gene            7244..7429
                     /locus_tag="LP386_000306"
     CDS             7244..7429
                     /locus_tag="LP386_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HBL1917577.1"
                     /translation="MPKTAREIVKILKSNGFKKTGQTGSHAKFYNSKTKRTVVVPIHN
                     GDVPLGTEANIWKQAGL"
     gene            7496..7891
                     /locus_tag="LP386_000307"
     CDS             7496..7891
                     /locus_tag="LP386_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HBL1917578.1"
                     /translation="MKTKNIFYPAIFEKEGEAYNIVFPDLPEISTFGNSLEEAYLNAK
                     DALGLALYSVPDAEFPKPSAVEELTLKANQVVVIIQLNIKLFRRSLNTKTIRKNVSVP
                     EWLVLLGKEKNINFSQLLQKALEEELLEK"
     gene            7881..8258
                     /locus_tag="LP386_000308"
     CDS             7881..8258
                     /locus_tag="LP386_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917579.1"
                     /translation="MKSKKETEPMKATHLNYFSRTLINNLLKDTTGISVSTKHFANDL
                     IIFEDNNLRIEMFIEQATPNSIPEFCYTHTEKMKHAKSVKDVETLSESLTNALNLVKK
                     AKLLFEFQTDYHNELLAQSEILD"
     gene            8280..8654
                     /locus_tag="LP386_000309"
     CDS             8280..8654
                     /locus_tag="LP386_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917580.1"
                     /translation="MKQTQTETINDTLADQLAGYYKLFEMSKAQRLIHYLWKYKILFL
                     FWEATLTFSVLFYKSDFYNQHLVLGSFLLIYTILMLNLYTYITLEEHLVISDAGIERN
                     IKRVSFKITLNKPTDKKLSEAF"
     gene            complement(8960..9358)
                     /locus_tag="LP386_000310"
     CDS             complement(8960..9358)
                     /locus_tag="LP386_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HBL1917581.1"
                     /translation="MKYFFCAVFEWKGNEYAVKFPDFPDLYTHGETLEDAFEMAQEVL
                     EGYLVLLELQEKEIPSPTPVQELNARIKRSENVNLFVVKANTKVAKARNKQNYDRKSV
                     TVEHYLNVLAAEENINLSKALNDLLREKLI"
     gene            complement(9548..10315)
                     /locus_tag="LP386_000311"
     CDS             complement(9548..10315)
                     /locus_tag="LP386_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBL1917582.1"
                     /translation="MKKDELTKYNEEFLATIDMKMDLKSYELYQLLFSYISPTKLKKT
                     GVVDLPVKAIINYMDVDQNLETELKTIVNTLQRQAVYEISNLDKKYKTYTTVSAIDRI
                     HWDLEEHSVSFSFSEDVIPLIVSIKKKYPFFVFKDLASFQKKYSIVLYKYLAMYYKKY
                     LIAKNKGDFEKAEIYKNPLIEIVKIREITKTENEYKTISNFDRRVLRESVEEINEKSM
                     LKIDFAKVRKGRNYNFAVQFNISSEFDEKPYREKKLG"
     gene            complement(10350..11573)
                     /locus_tag="LP386_000312"
     CDS             complement(10350..11573)
                     /locus_tag="LP386_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HBL1917583.1"
                     /translation="MESYQFQVFKLVPSLERRGNRMKITEKNVNPKFETTESNLKKFD
                     LTVTLSNQLVDSIVEMDAMPQKIYLYAIGHLDPKNPPFNNTVKVSKKALFALMSSSSS
                     SSKHSRLKQVIEKLHQQSVIKIQRTKPNGKTEYKVISPLEITEFNDFSDAVSIKFSSS
                     IMPLLTNLEDHFTQYTFDQVVNLTSKYAISFFQLFTKDFNLYEANRDNLTWSTKSLDR
                     LKNPVFSIADLRKKFSIEKKYKAFRDFERRVIKEPIAQLNKYTDFKIDYELIKKGHTY
                     TNIKFLLTRTMSVPVPYKQEQRDPAYLKGAEDKTEKMNQSYLKAMNSKYTKLLIKNFL
                     ISSADLCDLKLMSRLQNKVYPLYDRLSKDRGFESVVNHLSYVATHKEDYTIKNTVKYL
                     EKSITSYLPYVNLYD"
     gene            12553..13356
                     /locus_tag="LP386_000313"
     CDS             12553..13356
                     /locus_tag="LP386_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBL1917584.1"
                     /translation="MSQEVTEKIIDSDVDLVSEQTNAIVRYNNGLNTTALRGFKPVEM
                     DVFWAILSKMKRQGTAEVTFDFNLFRYLVKYDRREKDSFYSVLKALSDKLGTLTYRFE
                     DSDVYEQLWLFQKFRIDKQKETVTIKANEEFEFILNSIGKNFTRFELDNFTKLRSSYT
                     KELYRHLMQYRNKEWRNGYWVVKVEDFRRALSIPSSYRMTNIDKRILEQAKEEFLAPD
                     ENGIQVFETFDYEKIYAKKGRRVDRLRFTFSEPESNLPTISMHNWLEED"
     gene            13940..14395
                     /locus_tag="LP386_000314"
     CDS             13940..14395
                     /locus_tag="LP386_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917585.1"
                     /translation="MNAINWHEFVNYMESLLDDLKSFSIADAVKHGLPVSTTMKLRGL
                     KIPDEIIKLRTKTIIETAKVVDNMNHELKGKKTTYEKDFERFLKSVIGKYLGKKSFSE
                     LRDEEIVPTPMVSKIRKNKAEGNYYLGTIAKIIDYLENKEQKKGTKKGR"
     gene            14514..15572
                     /locus_tag="LP386_000315"
     CDS             14514..15572
                     /locus_tag="LP386_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliS"
                     /protein_id="HBL1917586.1"
                     /translation="MEKNVNSTSTKDQYSIIGGLLGDKDKRTRHGLRIMLATFLGVLF
                     LLTGLGSYIYQLGNYNYYLVNNTTPIGSSLEFARSGAEITISDVWTDQNRDVTVVKLG
                     YSQNARKLLSTQGKNYNLYMATKEKDRPKKLEMSYGMLSTDGDAFLFLKGKLDERAYQ
                     VFIANQVSLISGDDTADDDTKVNVNEADSVTKALSQYSMNDVNNEGVISFGKKAKPVN
                     TPDNINFRINPYSDSTNVYQGSFLTKDGDIDYSKVVAVTSKNNVVNKLEDQLNASNTN
                     IKKIEATKAEYLERLQQNPDDKDSQESIRQLDSRMETEIKAINDTQKLIDQYKNADFT
                     KDSFGDMKTTFKYLTLTD"
     gene            15614..17563
                     /locus_tag="LP386_000316"
     CDS             15614..17563
                     /locus_tag="LP386_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBL1917587.1"
                     /translation="MENSTEFFKNIQTEFNHALTPMKPPKHKLVGRDDELHELSLILN
                     RPETPQAILLGEAGTGKTALASEWAERQRQDGKKVQVYKLSIGQLRVGGDDVLQTRLE
                     TLIPRLKEYERILKSEDKENEFVLFIDEFHKVVSSFGSGNKIGGDSLKEPLANESLQL
                     ITATTRKEYENYIKRDDALGRRLQPLELNELKSDVVVDILRQWLNTSSVKDDPQASFK
                     LSQRIPDELLQEIVQANKLYREDLSEPAKSIAVMEDLIAKDRVDGNAYNRESLLQIFG
                     KYNIQLDSDFDMEKLQEELKSIKGQPLAVYTITMLFKRMKLGFDRFKGRKQPKATALF
                     TGSTGVGKTAMAKAVARGLYGDENKVLLVNMPDYKTKDDAMRFRRLIGTHVRHDPSAI
                     IVCDEYEKAGVETLDAFLSILDEGRISFTERGWDDREVHDTVSLSNTILFATTNAGAE
                     MFDSLNRYSSLSRVTNKENSNEYSTELKREYRKVASGIKQALIGEGLKPEVINRFGRI
                     VPFWALSEQTLLEIAYNEMLKSAELVRKHLNIDLRLPPRKERVYGQNFYADDLSMHLV
                     FDMASQEDSKSGGARNILHLVESEFEEAITEAIITYPNAKIFDVKLSEAGAFEGKGDS
                     NAEIIAKPSVAESKENKIVFSIGGA"
     gene            17566..21207
                     /locus_tag="LP386_000317"
     CDS             17566..21207
                     /locus_tag="LP386_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917588.1"
                     /translation="MKFKKYLLQNLRIKRWVVRGLVIGGVLAVTLGAPFGMNDPTPDN
                     QDSKQETVINKNVAYAESKPAEQGMWTLYARILMGDKEVNDSAAKTGQMNLLGQGGIS
                     ADFPYSDISKQGNSIAGGNAGTQLASTLATYSYYGYIETVSGNAIASQASSILGSIGR
                     TIGSFIGSISLILSNIAESINELLGKFFMSMNIFSLMGWGEGGSDVSNPVSKALTSLL
                     NNLGLNNELFKAIASLSMLFFTAILGYQGMKLLSKDGVNSKGLSPVLEKWIVRIFVLF
                     IFLPVAGSLLGVYINGIQSAKKDGDIPTNVVSDYIINTRLWASTQNLAPSSDTGGDVP
                     DGKPTSEIKFVDTDYEPSKKSAMIRAINTSSYARQNNDLDSNSVGMALLKEWSSNDTF
                     NINTYAGDVNVAENDAYMGRAPAVWTGYNLGDGKEGSAIKKPTNLNGYIWSANQNVTD
                     DNRKPDGKGTAHNFDATQPWGVANNATFSTQSVALLLQSALDTSGAKFYAYNIAPSGI
                     QGSAKNMSTVKTEWRTASLVGHGAMGKFGSWLAMNAESIVLAVLYLACAWAMFNVNIV
                     KAFKREFMRIWEVVLTGSLASGAGVMAISLGVVTTSLIGLQLPIFLITFIRAFGDTAV
                     GFIPNTLVGDGVANIVRSAMILGVGYLLVFKKGEKVNNLINMLIGLPLEVAFGFDERA
                     KLLFGNRNDAVRVVDGVSKAIKKSQGAKNPYYDGGNSSVKDMVAGGLGAVGAQKMAER
                     LNNMGDSNADAKSIADKVIPETPEGMSFNGGGVGSTINNTSFKDLVRQDQLRNNSQQY
                     IDHLGRMVDENGNFVDENGEILKGSKYGKDAKGNFIDEKGRLVDEDGNLIDTNGKPLE
                     DSEDGNIGMDSEGRLIDEKGRLVDEDGNLVDEKGRRLLNGDFGQDSNGRLVDEKGRLV
                     DEDGNLVDEFGNKLGKHSDGYNVNGDLVDEDGNIIETRDALVADRNRELEQQRHTPIA
                     VAIPENEDDEITLDQTHQELRNEMSGEDVSDRVHRELGDGASGESQSRELNSNFDNSA
                     IRNDTALKGRESLTKETDKEQSDVKKKFIPTPNVNQTDKYETNIGSGMSKDNQSIREP
                     ELTNENNRTNNSKSTSDNSGKSNQSTKKPSTAKSAVEYLSKTGKNVYTSADKALAKAP
                     KGSLAGITYEAKNEAIKIGKGTAKIAKATATGASKTGKVVKKSTMSVKDYIVKYGNQK
                     STENKSEDE"
     gene            21607..21945
                     /locus_tag="LP386_000318"
     CDS             21607..21945
                     /locus_tag="LP386_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917589.1"
                     /translation="MFDSIKNLVSGMTPDMKTLVQVVLYFLAFVFSLKPGFTAMKFFG
                     DAKWGDGLKYVGAIIAIFIIPVITTVMLYTMGTKTGNDLNQKANIISALIPVVGIYLV
                     SKFPKNEQLG"
     gene            22055..22297
                     /locus_tag="LP386_000319"
     CDS             22055..22297
                     /locus_tag="LP386_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917590.1"
                     /translation="MVFDREKMLTHADEVLMSGLKGTELAKIMNMNVNQFYDYRNGSK
                     KIEKARLETLIKFEKAYVYMLDKQKRTIDRKKGVLQ"
     gene            22297..24453
                     /locus_tag="LP386_000320"
     CDS             22297..24453
                     /locus_tag="LP386_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917591.1"
                     /translation="MAKFKDITESINYVAETVPVVALSLKPQLLEAYQKEEKEAKAKK
                     AKAKVWKEFDALLTKDLPKKNYMVIEDVQKLNSEGVIDEGDAILDSEKYVVLLKSSLN
                     YVADLPEKFKEKLLAGVRFMDSSGQLLVIPDDPNMFESEVEEATDFYSAVEQLEVATN
                     GLERIAETFNSSEEVEFEAVAEDVPDEKEALFVDDNKPTEAENQEVSIEETQIQTETY
                     QQPKIDEKPESQSDKENYVYEAEKITSASDVPKNLDADFLEKNFEQIIADKFQPVVLD
                     EINDPVDLNEEMLSIPELKPLLFLAKESMNTRISIANNKINSELNKTKEQLILKGKQM
                     LADELLRIEEATSLNGQNQFTNTLSVAKESYEAEASKIDDLVMEKSSIIRKDYDMAKQ
                     AYLDAELKKLEQRYDAEHLPEVKQQEDEYRKATEESLDQQYQEAIESIKNDALKQSQE
                     AKEVVVERIINSLKPEIEKSLTDVQEKTLEIVEKTKSENEAEFHDTKEKTTDVVVKYF
                     ANKEEVEKQVANNTKELETKLVEQQKTIEEYKDRMKEVKDLAEGYKLNSEKLAEQSEA
                     LREDLSRSRSDLAQMAEKTKSLAVATENQSSSKRDFTSKKMATIIAVAAMACGTILGS
                     SYFISHNNQQAQAQTQTSISRVENSIGTNTNSASTNSSYEATPTTEFKVGKDVVISID
                     GKTTKAEVISIDGEKAVVKTPDGNQYKIQAHLSDNN"
     gene            24465..24698
                     /locus_tag="LP386_000321"
     CDS             24465..24698
                     /locus_tag="LP386_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBL1917592.1"
                     /translation="MREEKIVYPVIQNNQENITSSQHLQEAQLVYQVNELPQTNETMS
                     KSISLIGLLIVAIVITVGVYRKLNVKGSISDGR"
     gene            24688..25554
                     /locus_tag="LP386_000322"
     CDS             24688..25554
                     /locus_tag="LP386_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917593.1"
                     /translation="MADNSNYGFKHNLHQKPSETIVRVEWLEKHVNSTYSVTAKRLIV
                     SAIVVAVVVLGSIVYLVSDTIKLKFIFVPTLLMIIGFLILISQYMFIDPSSGSLISGS
                     IRLFKSVVNSARVSMGKKKPFRGTEILKVKQDGTIVYRDGSVALMFNLDGATSLTAFP
                     EEVMAQESKSIQYQNTRDRSLAEIKITSSQPQNTERQTRNMKIQKRNARSNKAVFDII
                     DQQERFVSEYIDGVKTTVIQYLILKSQSKMVLDEGVERLENYTSRGLYYSVTQLSAKQ
                     TKEILSDIYALK"
     gene            25569..27539
                     /locus_tag="LP386_000323"
     CDS             25569..27539
                     /locus_tag="LP386_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917594.1"
                     /translation="MEIMGRSQLLNFKKKRKTKKEQKTRNSKVVNNTFVSDLTSLVGY
                     QFTPSYIRTGKRWGTIVKLVNTYGMNRNYGFGWMVKAIPEVRVEGVKAYLIEADKPVS
                     QKDQQEIMHENVGGSTNSYENNLEGKNSDAEISKTVMRIMDLNTASLLDSMANKIIDW
                     KLEILLVSDSPNKISEQLIKLQRLYDEKMYGLKLMSYGGDQRDLFDRLLSEPIGNVYE
                     YTSMSSDFAGNDHAIRKGLDDANGWAIGTMSTSYASGVAFMALDDSFTSKVLVASHKN
                     ATIKGYDEKISASSLWGQLIANNAMANHKRTFHIVLNKFDYFGDPTGRTFVAKPSLNS
                     VIEKVNLAEEGLNSLELFGNQKDIGDLYRRNLDKLTQIFYLLAGRTLDSATRVLLKKE
                     LGNFYISQKLWDINYEERSKLLVNSSDTMPVLGDFISYLTNAETKAKKSGTEKEVDRI
                     IVLKDTLRTALDSFSRMFNQRTTLKEIGKSDKLQFYYNLGDLRVETNVMEAQFLNTFD
                     FITSQAKKDDIVMIHGFDKLSIETVGLIKKRLTMLEEDGIRLAFLFDTIGSGEDNEYK
                     EDIETADIFNTDGKIYQSFESDFNYTIIGKMTSGELMKYEKKVAPARKGEDDQKLSVD
                     LRQYLTTGRSNKFQIRRPVDLTNNFVIGEFIL"
     gene            27706..27933
                     /locus_tag="LP386_000324"
     CDS             27706..27933
                     /locus_tag="LP386_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917595.1"
                     /translation="MKPNIKILDRIFLGRDTEVILIQHEEGFEVSIGIQKLQKPHYCN
                     QLYKNFTDEEKARVFFNEVKGMREQYEVVEA"
     gene            27930..28424
                     /locus_tag="LP386_000325"
     CDS             27930..28424
                     /locus_tag="LP386_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917596.1"
                     /translation="MNKLPEKNRVFRLKGDLSQFKIDENGQFFVWMRHEHCWCNPFEL
                     KKENEIRTKIANGEWDYLFRWEDESFIANDMDHAFVSFLDNTWGTWYDCYLEKLGFQN
                     IDIDAIECLKEVDQKYEEEPYYLLQQKLANNSVFQVEIWENEDGTYEGLAQEIPFSDR
                     KSSI"
     gene            28599..28934
                     /locus_tag="LP386_000326"
     CDS             28599..28934
                     /locus_tag="LP386_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917597.1"
                     /translation="MKQYLNEWKAIEGSLVTQRIKELPDCLEKDHLFQIREMLKKEQF
                     DPDQFLVVEYPTIGVYCCNHINDGKYFIIQEYGGQLTPFYTTWEMSEEGINNFPCESI
                     EDSISHTEC"
     gene            complement(29191..30774)
                     /locus_tag="LP386_000327"
     CDS             complement(29191..30774)
                     /locus_tag="LP386_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917598.1"
                     /translation="MFILDDEIKKVKNPRIIPLLEEVRSSFYQGNYRSAIAVNYSALV
                     LDLIDKLSDLANIYEDITSKKILEDIARLRKSDPNSPKWEMELLEKAYSSTELIDSYE
                     YEDLKYIKDQRNYSAHPVVTYNGNTWELRDITKETCQDVIRKSYEIIFLKNPILGKKV
                     TIEIIQYASRIHAMSVTPEEFHSALKNSYLNKLSEKAKENLCKTAFKFVFQLPYGNEE
                     ADRDRESTFRLLNALIFDNKEFYLKILKEEISKYRFTAESREEINKSLGENQQITYTK
                     GVFLLTFIATHPELQHDFSDETIQNLQISINDFKPKQQVLTEIEYYYRLRSLAVLGSN
                     NEELQNHLNSLLDPILQQKMRVSSLPSSTLETIYNQYLYFGEKEMFIDFMIEHLTDAS
                     SFRLADKDMEVLPWIYNKLNQEQFNKLLYNLNGNNQFYKNSNFPPFISNLLDFYNQKF
                     QVNLRKHYSGLLYPNAVTMDQGFQLKDKELKNLYELAESKSDMYLDIIDNIINKSEDY
                     LRKEINSEKELLNYVHKIK"
     gene            30896..31480
                     /locus_tag="LP386_000328"
     CDS             30896..31480
                     /locus_tag="LP386_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917599.1"
                     /translation="MDLKQSFYIWLYPDNPMSIMADIFVVSILLYLFYLIFFHNLIGY
                     MILDWKGMFDIERKPFANNQTYTVFESGDWEENEVDVIHEIGLALSGIQDADVLVSMT
                     TDTGYNAYEVFYLMYFIWRDGQEIINGRAEKTIISNTEISFCMGEGEMIVYKDGSANI
                     KTAFGDIETSIKELREYVQNPYNFQYLAGRINLV"
     gene            31491..31736
                     /locus_tag="LP386_000329"
     CDS             31491..31736
                     /locus_tag="LP386_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917600.1"
                     /translation="MKKIINQPTNHLIIEGVIFVTMYFTVGNGISNTIIQKNPQYLLF
                     SLYAWIVQMVWVSILMLLFYWIVRVILLLLNKRKKDR"
     gene            31742..32464
                     /locus_tag="LP386_000330"
     CDS             31742..32464
                     /locus_tag="LP386_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917601.1"
                     /translation="MKSTKLKVVLLSTAALITLTACGTTNSANNNKDTKSSSTMVTKN
                     STTSASTTMSSMTENNAEKYQKYEDINKDQKPDEVYNNFINTVKNDENYGNDPLQNKN
                     LTIVLYKPDCPDCQKAESKIMQEIKEGFSYAPTLMHDITINKPAYEYYAVAVDITDGV
                     PEWVQNIPGLADENNQYHTPTVAVVTPKKVNGTLYWDVMGMTTNTTDEMIESTTKYYM
                     DLGAYKLYQQSEPVMDDQSKVK"
     gene            32595..33338
                     /locus_tag="LP386_000331"
     CDS             32595..33338
                     /locus_tag="LP386_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917602.1"
                     /translation="MKEISANEAHIPQKNQVGIYKVLHGEGIYKIQLLTGYNNGANGK
                     WLKATSIRELRSEVEKIRLGLTSEEIAKLKGNNSFVIEKEKEKHLLYRELKIEEYYEI
                     DLPEKLRIIDQRSEEKWKTEIYPSLNDYKTSGKPMYNYTGFLTYTQYKYAFRKLKGIK
                     QAEIALYEMKKVDRLKLIQDLVQNTWNQAIVELEKENGKILTNKYLIVNEIEELIGLF
                     SCEKGEVFLKSSPTYSILDSPYQFIQARR"
     gene            33344..33709
                     /locus_tag="LP386_000332"
     CDS             33344..33709
                     /locus_tag="LP386_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917603.1"
                     /translation="MSSLKDDYIQAKQEYEKIQMLKSEKVELFLTQKLAEDHIANLDA
                     KTLEEYDQQFNQIHHNIILLVEQAKRRFEKAEYDLLDQGIVCLDKGLRRYYGAELKKQ
                     NVDRNALKHEILELIMQRI"
     gene            33725..34255
                     /locus_tag="LP386_000333"
     CDS             33725..34255
                     /locus_tag="LP386_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917604.1"
                     /translation="MSQNISAVKQLIEEDLETTVQRLAERIHFANYQTISNWSSRNRN
                     PEEIPMKFFYRIGKEYGVDPIKIFEKTMIYYYHGTPNEVLEHLLEEAKEKSSILELSQ
                     NDKVIQVKCVDPTGKIIVGFDIERKSKIDFITQLKKINNLDILTLRPDHEQLFMSFKK
                     QLKEIQKRYNKVFPNA"
     gene            34417..34806
                     /locus_tag="LP386_000334"
     CDS             34417..34806
                     /locus_tag="LP386_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917605.1"
                     /translation="MWNNRLKTGLLLIVISCAMMIGMRIQREQSYFEVSANNVIEKCY
                     YGQHYWSEEVRENIDREYVQRIVWDAYSIKDYPKSLTSRLFYSEKDNQKLSDLMMKKV
                     SKLAQSYLEEKAGAIKDKEEMEKFAIE"
     gene            34799..35188
                     /locus_tag="LP386_000335"
     CDS             34799..35188
                     /locus_tag="LP386_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917606.1"
                     /translation="MNEETELFIKKVNFLVEKYFFTKHKIMYLIKGLIGGIILWILTF
                     FSLFGGFTNYKKLVDENVKQISASESLRHQAEDLVSNPLFIGGMVEVIIISFVIGYLG
                     MCIFQIIFDLIRGKVFQGFKSEKINLR"
     gene            35218..35442
                     /locus_tag="LP386_000336"
     CDS             35218..35442
                     /locus_tag="LP386_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917607.1"
                     /translation="MEQTNHITEETRKFICLESFYSEGRYCNKGETYTAYPIEGGFKL
                     VFENGDMNFTTELFECVVETWSDVLLEVTK"
     gene            35495..35755
                     /locus_tag="LP386_000337"
     CDS             35495..35755
                     /locus_tag="LP386_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917608.1"
                     /translation="MAYENLQLVAAGVSGDIYLAKAKDGIMDTNYRRVATDDVLSSAT
                     EWFRTNEESAVHFKGIDGNIHSLFYTKDKEKAKKILDILKES"
     gene            36094..38334
                     /locus_tag="LP386_000338"
     CDS             36094..38334
                     /locus_tag="LP386_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917609.1"
                     /translation="MSKYKFLDINVGSAFLINLDMFEAWAQSSGYNWAFSDDMIEFLS
                     RTMSWESYKVKQFLDVIAKPIYTSADDHWSGRELATLKELAEYNKNYNIPFQVSYTTD
                     DFSVIYALGKESRYLIPNRYLEIKMNSDYTNYTLGELKALRQSDSEEFSTLKNEVSTE
                     NFRISDIEELKKQQKQQLEKQKKLIEDIVNKRVDELAVQEAKIEKLRQELYEKQQSML
                     AEANKMRFELEKKVEELNTKIFYLETEIDAIEGYFGESTTFVQLRSGQKSLSEDPVVM
                     FQKVRYLDEELGRYFSMREVEGTADTMLTFEQALSSRDDLFDLFSPNKKSISMIRISK
                     SGYGYTNGQMESTNMLEKYKKYHGETLAILLRNGDNLWICWLDENKISFKDDLFYQNK
                     VTEQASETKNMVKEIDWTHTRNLEERLKDAKKQKKAVRGEFASRYILFSILQGVLDNG
                     TMMTLPEKVNVIQAINQKSPYFIASVADGWLEDTRLPSFSELIDKYSFYKETGEDRVL
                     EAEYELNPDKFENMRDYPHKQNDDIYVLYRLRGWSPTSANYSYYNSDNRSNSESGRDL
                     AYSIDLKDGIYQINLVKQGKFHKQMFSRTFVGVDSTTGENIYDYYYERETEYYIRGQK
                     AYNKSDYWGDKAKRLTANFRVYESEFINLTFLNSVFIDYVITTKRIGSYSSTYASLVP
                     MLNSMSRFLKEREEKELQYIKEIMPDFEMHEWQIALSDWKLTNKVRRITPFQAKRFLK
                     AMKFVK"
     gene            38472..39269
                     /locus_tag="LP386_000339"
     CDS             38472..39269
                     /locus_tag="LP386_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917610.1"
                     /translation="MSEDLRELKLRKKQYDQYFSGLLNKHIEEGLDHDFGKDEYCLYC
                     ERYNEKMSEYLQLKKEIQKLEKKVHAWKYKDSMSGYGESQNKPRKKKQAYVLKMVNGE
                     ELIVLAYSKEEVRELVETPVRKKIETINEIDDSQYNSIYIETSHGGYKKLATFLRSSK
                     VGIISKKDISAVTDSFCTLSVPKAYFQYNSNRFDRLEKFCRPYTVLKTKKFNKTKRVS
                     IKLPTGQISLGEKDYLIKVGKELIIKVPERLFKENFEIRETLVWKEE"
     gene            39309..39491
                     /locus_tag="LP386_000340"
     CDS             39309..39491
                     /locus_tag="LP386_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917611.1"
                     /translation="MAVNRKLQVLITDDFGGAEWFDVQSIDFEEEVIVIENVYGEEYS
                     YSLEGENVEDLRLIGE"
     gene            39529..39696
                     /locus_tag="LP386_000341"
     CDS             39529..39696
                     /locus_tag="LP386_000341"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917612.1"
                     /translation="MYMIDKKTGKRIFSSKDEVIRDLSENFAPIELFFHQLNLEIEKL
                     LKEPTECKWPS"
     gene            39786..41012
                     /gene="istA"
                     /locus_tag="LP386_000342"
     CDS             39786..41012
                     /gene="istA"
                     /locus_tag="LP386_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003331415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HBL1917613.1"
                     /translation="MRKDIYEGVLPFIMTHTKPNYAALAKQYNCDYRTVKRYYEAGIS
                     NKLPLLAQKNKNKKTLVSDFEDIIADKLALGCSSSAIYHFISKRGYRGSARTLRRYCR
                     NIKADKIQKATIRVETTPGLSAQVDWKEDLKLVNKFGEVISCNIFLYVLGYSRIKYLE
                     LTFDRSQTTLFRCLTNAFQYTGGVPTEIWFDNMKTVVDRSRSQFSKVIFNERFRQYAK
                     EAGFLPIACRAFRPQTKGKVEALARTIERIRVFNYEFESTHELEKIIQTIMDSLNTEE
                     ISQAIHECPSDRWSYEKEQLSSFDANQLKIYASVEKQIKRKVSNEAMVQWNQNKYSVP
                     VNYIGKILTLRVKEDKLYIYDDSTLIRTHTMTHQLLNYHRNDYIEILRSDVFKHLEDE
                     ELERFVDENLQAYDEL"
     gene            41027..41782
                     /gene="istB"
                     /locus_tag="LP386_000343"
     CDS             41027..41782
                     /gene="istB"
                     /locus_tag="LP386_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HBL1917614.1"
                     /translation="MSNYYHLLNKLEDLNLKHTREILPEYLDTIVQENLSFVEALNHL
                     MTEEINSRNERQKENRLRKANLPFKKTINDFDFGFQPKINRTEILDLCTLRFMDTNNN
                     ILFIGNSGVGKTHLAIAITLEAITKGYSCHFALSNELVNRLNRANQRGNLDRLLKKYA
                     SYDLLIIDEIGYLPFTPDGAKLFFQLINLRYEKKSTIITTNIPLSQWAETFQDKKLTN
                     ALIDRLVHHAKIIQITGKSYRIKDYKEKKLSYK"
     gene            42066..42353
                     /locus_tag="LP386_000344"
     CDS             42066..42353
                     /locus_tag="LP386_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917615.1"
                     /translation="MAEVKFGSKEWFEELNSMIQFPEKFTFYYNKRDNIIQVALLETK
                     GRLENTRWSMIKPSALRFHPKDLTAVVAVKEVQDSQEYYEVVKNLKDIWCK"
     gene            42444..42683
                     /locus_tag="LP386_000345"
     CDS             42444..42683
                     /locus_tag="LP386_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917616.1"
                     /translation="MKELEGIKKRNQERLELLNENRNRMFSYYESMRCLNKSRSEIIE
                     SSKYKQLMEERVSLIQEIETESIFPDHFPKVRFYN"
     gene            42811..43140
                     /locus_tag="LP386_000346"
     CDS             42811..43140
                     /locus_tag="LP386_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917617.1"
                     /translation="MKLEGSLQNRMMEGRTTNKEIVVGMGATELLYTDRNPYTVIEVK
                     SKNRILVQADGAINKATFPDQEWEYSRNPEGQILELIKTKNGWKVLKEDTHFYIGDRE
                     KYYDPSF"
     gene            43193..44041
                     /locus_tag="LP386_000347"
     CDS             43193..44041
                     /locus_tag="LP386_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917618.1"
                     /translation="MFSQEEIISKSQPDKNGTITMKKKIPCYRCSGSGQYKFMSMGKI
                     TYGTCFKCDGDGFLVVTEKSFTPEYRAKLNALNKKRADRKIRITREKESQKNFDRYGF
                     EKGYIYVVIEENSYAIKDELHHQGATYDPLLGWFFKEKQEQYKTQKVFVEEFSVINDE
                     GIIELKLEEYSERQQEILRAKRREEGEFIGTIAQRLELDLKLTNTVTIDTQWGNVYLH
                     LFEDKNHNSLIWKTNKFLYYDEWDVGEVRKVKATIKAHDYYRDTKQTWVKNVKIQKNE
                     SEGIKV"
     gene            44038..44355
                     /locus_tag="LP386_000348"
     CDS             44038..44355
                     /locus_tag="LP386_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917619.1"
                     /translation="MKREEYKQRLNELLEEDETLTHGSPDEILYMIDNMVIFGGYELG
                     NRSVDHNILEFDDVSWEEILDWGILAVPETKTYISDTMVPFFEELDYKRLPKNENHIL
                     GGN"
     gene            44358..44590
                     /locus_tag="LP386_000349"
                     /pseudo
     CDS             44358..44590
                     /locus_tag="LP386_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321015.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(44627..45106)
                     /locus_tag="LP386_000350"
     CDS             complement(44627..45106)
                     /locus_tag="LP386_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917620.1"
                     /translation="MTDKTSDLPKLAPKTSRVKSKKDGKTKNAVKKKSVKETSSLLLD
                     IPMSSFDDNTDETSVKIATHVGMNNQNDSFYNLLNSLRELEDKKNQVIASKAPDLTTD
                     LDAEIIQIKQDERSVKSLLKTYFDGFDKELAPYSQAILTKPIQAPHISISLQKKSDD"
     gene            45226..46563
                     /locus_tag="LP386_000351"
     CDS             45226..46563
                     /locus_tag="LP386_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HBL1917621.1"
                     /translation="MLIVQFTGIAMSVITINPQVIHADGIATYDAQFNCTTEGSGSGT
                     DSDGNDTGSGAVTGDVAKNIEDIYKYMNGEYGLSGASIAGILGNWKQESGIDPRAVEG
                     YYGDGQREVDFIKQFTDGLMGIGYGQWTAGRHTALVDWSKKNNGGSWWTTEAQLDFMF
                     KGDGGFVGILKDYALNASDDVVENAVTFHKNWEISADSESAVIAVRGENAKEIWKYMK
                     SKGMDGAKDESKINKISGGSSTGDGSNNSSSSASGTVEDACATTDDANSGSGSIGKEG
                     KINGKKGQVIANMTYEEALKKYGKAITLPKFKEPDWSTSPFNGIYQGQCTELTWAYMS
                     QLYDGNQPTTGNGGYVWESYKSAGAKITNKPIVGYGFSASDGWLWAVGDAGHTGVVIA
                     VFEDGSFLCANFNVPPTQAPTRGVSVTLIDGVDGSDNVHFFSGVGKAKFEIEK"
     gene            46586..47113
                     /locus_tag="LP386_000352"
     CDS             46586..47113
                     /locus_tag="LP386_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917622.1"
                     /translation="MNSKVKDTIIISLLSGMLLALLVGILFFNKQNQDIEAEKHSVHI
                     EDKLTFFKEVKPNEVDGLRKDLENDIQEMLNGSVQNKFADQSGEEFLRKLFIVTGKPP
                     ITDKSSEKEKIEYYKPFTFKLTNFGIKTSSSGLYEALTDFEVQYNGKKVYDTTLTITL
                     NNDKKVTGGAFYAKS"
     gene            47100..47663
                     /locus_tag="LP386_000353"
     CDS             47100..47663
                     /locus_tag="LP386_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917623.1"
                     /translation="MQNHEITTAKKAIGILSIIVILCCVVLFQKKNAYDNNVKELEDL
                     KSKQIEVVKNNQKVKAMQEAQYKELGNAEIKEQSRKFFNLFYNWNSWEKYTKNMKEIQ
                     KEFPQIVKSSPVDISGTMVGTGNSPISSYTADYYTTNQKGKMVELITQTRNTPTTATT
                     TIWRGVTSIGENQLFYLEDLDSYVRAE"
     gene            48085..48822
                     /locus_tag="LP386_000354"
     CDS             48085..48822
                     /locus_tag="LP386_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917624.1"
                     /translation="MADHKLEKLLEETWNPKEFSEFFMENFETDLAVIVKDALREQGY
                     PETANYININFTLYTENKGTWDFWATLANKELSDKSDTGIRNFFESNRDDYMYANNQN
                     KLNFRVEFDETPEEFIERQPPKENVAKVLEDRWNSDEIVSTISELGGQYEPLVEAVRE
                     ELRLNKFPDVQNIDVSQIEINVKITNKLDYGSWADIALEKYIYSTLKEFIENRMDIMY
                     LQHPQYLNFGVEIATPLEEWKMEQGLD"
     gene            complement(48839..49255)
                     /locus_tag="LP386_000355"
     CDS             complement(48839..49255)
                     /locus_tag="LP386_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917625.1"
                     /translation="MNKKRKLSVLITLISILTILSGILSLKIFNQINTSSNAKDGIVV
                     ENTSNSKETGTTTKKDKSSEITTKNYLIKTVYFDERKTAILKDEEGSELKLPITVSDK
                     FNGTFSLQTAEGSPDNLKVGQTIILGKNDELYSFVK"
     gene            49647..50894
                     /locus_tag="LP386_000356"
     CDS             49647..50894
                     /locus_tag="LP386_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HBL1917626.1"
                     /translation="MNMKKNSLGMVLFASAVLAGLSVPVTSHADEWTANTPDQIQITT
                     GQSSYAFKKGDTIWSTVEKLKSLGYKTTVAEFAELNNVDLAKGEQRTIPIGRTFNISK
                     DTLTVKEADGEVVSQTVQKDKPDPVENTEQENKKSETTKESEPTANTSDKTETSASSV
                     DGASSSNTNNSTSEKEASQGTSESSTTEADTGTSTNNSQSTSNDANESTSTSSSDQSQ
                     TGSSDETDSSTSPSKPEQPTNVVLGVPFISQGNTMLCEGTSLLEALHYKGVATNQDLM
                     TFVKSMPLSPDNNPNNGFSGEWRHNVDGTYQGMNPAPVVSWGVANGGNVVDISGSSVQ
                     GLKDEIVNGNPVVAWVTYAFEPAQHKSMFWGDAIWNRHVVAVDGFKDGFYHVVDPVFG
                     ASWINAGSFETAYNVSQLAVSVR"
     gene            51031..51174
                     /locus_tag="LP386_000357"
     CDS             51031..51174
                     /locus_tag="LP386_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917627.1"
                     /translation="MLSTKKVINRCGDFNLGMGAKVITTPTYRGSFSSPNLHKEGVTR
                     DEA"
     gene            51164..53554
                     /locus_tag="LP386_000358"
     CDS             51164..53554
                     /locus_tag="LP386_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HBL1917628.1"
                     /translation="MKHEKTIILKSKIIYCFATLVMVLSTLIMPFSAIRAEADVTKPT
                     SAKFTETGVKTDGYIRVNMPNHPNEWMISSQFKDSHGNIGYCMDSELPSPTGSGAGSL
                     KYKGDGSDEFYRMFKGGFPSKTAKELGAGNDTEAWYATQLVSWVLAGNFKVSQIVWSH
                     PNHTAAETARVKKAFEKIYDYAKNGKDTPNTEFSITASKTADEGKYHTFTYKTASNKT
                     GNAKLTFTSAKPAGMKIYDADGKEITNNTVKLNSSFTIKVPVTTPSGTLSFKGTANVS
                     TTNPFTFDGRGVYQDAVVMITTSETKDSKSLSAKWTRAVGQVTVKKVDQDGNALKGAE
                     FTLTDNNNAKSVKTTGDDGLATFDLQQGLTYSLEETKVPEGYQGSFKKDGITVNTDGQ
                     EFSYTATNTIKKGKVKVKKVDQDGKPLANAEFTLTDDSSQTQAEKTDENGLASFDIVA
                     NKTYSLEETGVPTGYTGVFKKEGITVKDDGQTFEYTATNTLKKGLVKVHKVDQDGKPL
                     ANAEFTLTDEKGETQVEKTDENGLASFNIVANKTYSLEETGVPVGYTGAFKQEGITVK
                     DDGQTFEYTATNNLKKGLVKVHKVDQDGKPLADAEFTLTDEKGVKEVKKTDATGLATF
                     NIIANKTYNLEETKVPTGYTGAFKQEGITVKDDGQVFEYTAKNTLKKGVIKVHKVDDQ
                     GKALANAEFTLTDDKGVKVVQKTDSNGLATFNIVANKTYKIEETQNPNGYTGKWSKEG
                     ITVADDGQTFEYTVINHLVPETVRTGGIGTSAFLLVFLIAGLSMVLLYYREQHKAK"
     gene            53603..55438
                     /locus_tag="LP386_000359"
     CDS             53603..55438
                     /locus_tag="LP386_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBL1917629.1"
                     /translation="MKSKKIFSNLMLFGTLLGVGLGASSISSSLGLGGQVAYAQQNYN
                     YQGTGTIHIHKVTNTNGDGNPVSDIDNKGKEIALPNGVKPLEGVEFSYVKLTKDEAKS
                     LGWTDSDTTKGQHIDDAKARLLLNKKYSEVSRMKTDSQGNIDIPIQVNTDDLTDNLYL
                     IVETGTVKGVVEEAYPMIVNVPELNGSDDQYFNYDVHVYPKNYFQLNSAELDKKDEDG
                     KALAGTVFELRKDDGSDQVVGTYKTDSTGKLTVDGLELGDYYFLETDLGTDANKTTYL
                     LDGKKFKFSVKRGETAKVVLDVTNYKRPVITKVIDKETVDTGEDVQYTLKPSIPGNIG
                     NYEKYVVKDVLGAELTYDSSEVIEGMTLDTDYSIERDGQTTNYVFTESGMDKLQKQFD
                     AGDRFFTILMNAHTNSKAKMDTPLKNDVSTIYNNGYEPEDETPVDHAYTIIGDHQFIK
                     TDGDTSKALSGAKFVVKNKIDPNKVTYLKQDPTTKAVTWIADKSKATEFVSGSDGKFQ
                     IEGLQYTYDVDFDKQGNPTITDKKINDYALEEVVAPSGYTPTRNDIPFVVSNDDASSE
                     VTDIKNLKTPETVRTGGIGTVVFLVVAGVAGTGLYVVYKREQHKA"
     gene            55507..56370
                     /locus_tag="LP386_000360"
     CDS             55507..56370
                     /locus_tag="LP386_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL1917630.1"
                     /translation="MSMKKKNIKLIILKIGMLLCLGVGLYPVITQAYTYYQTQQTLNS
                     YKEKYDEASEKENEEVFKRYSEVNRKRKDTEQTSVTIPEDNNNIPSNGNLQKDKLGEL
                     VGEILIPKINVDLPIYDGVNDFQLSAGAGILTGTDYPTGGIGNHSVISAHSGIPNKKY
                     FTDLELLKLGDKFFIDISGKKLAYQVDRIKTILPTEFEDLLPVAGKDYVTLMTCTPVG
                     DNSHRLLVRGVSIPYQKSIVEKEKKKEDLKVKAQMNWYPIVVVGVLLIIAVIVIIKKI
                     VAKRRGMKNEE"
     gene            56360..57439
                     /locus_tag="LP386_000361"
     CDS             56360..57439
                     /locus_tag="LP386_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL1917631.1"
                     /translation="MKNKILLFLTLICTLVLTIYPANQLYHQFKTKENVAEIQEKIEK
                     KQTPSKEEVAKKVEQIKSNSGNQGLDNTQKTDGESFDIGEAEGKVNPYTGDVFSKNQT
                     KDFEPSTYSGAVGYVYIPKINVLELLFLGASQEHLYRGVAQMSATSLPLSGKGHQTVI
                     AGHRGGYTSPQFLYVDQLVAGDHIYIDYLGEKAVYTVFRTDVIRNYGQNSTLTDIPDL
                     DMLTLYTCHPYPQNYDRLLVRSLRDEKAKYITPQVTVGNTAYADAIDSESVSDKPETV
                     TSSNDLFEDVDRANKELDGNNDLNIPEQGSVEMQDRTFAEKASSIFTGITNKHQKMLL
                     VIWTVLGALASLKVLILLIKEFRKA"
     gene            57778..58578
                     /locus_tag="LP386_000362"
     CDS             57778..58578
                     /locus_tag="LP386_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917632.1"
                     /translation="MVEISKTALDSLAKLFSSRFDGAEFVEYLSQNESGKTLIETLKK
                     DYLNENDFPTWTNIEDATWDVVCTIYSPWVTIADFVLDKIGGDTYPDAKSLATSDFKT
                     FYGYLIGLIGNGIDLKVTPKQTPEEIEKEKGEVQMAYANDREKVKLLEGKLSEEELGK
                     MVQEINEDSNYFPELKVYQNDEDFFNEMFSNSPWEAVSKTNLGEWNFQDDLVAFSNDG
                     YLRSYSESEYRAELKTYETDILMSYLNLLESGQGELRDKVEELLKEEL"
     gene            58666..59472
                     /locus_tag="LP386_000363"
     CDS             58666..59472
                     /locus_tag="LP386_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917633.1"
                     /translation="MRGDQTMSATTDMALEAVIKDNTGNVENVEDFSDIAINLSAWIS
                     AVGEENIEFEIKNMDDLKAKFPFIASKLSQVAEDKSWNELVSFSEKIYDITQEDECVS
                     WEMNNQYKKIDAFVKSRIEGTAFEFEGIDTADNWLNKESFIKSIADDLEKQWSKEDYA
                     EYLKTERDTEVKEKLTEVCLDEHIDPNIVKQEDYEVVIDKVPTDFEEVVKYIVEEALS
                     QYSSDEEVDEETVRTRVWQLVFDDKDYKYLSDQNSVNWSVRLLIDQNDIE"
     gene            59704..60573
                     /locus_tag="LP386_000364"
     CDS             59704..60573
                     /locus_tag="LP386_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HBL1917634.1"
                     /translation="MEKKKFSRSLLGILVLVAVGLSGKGYFQNNSTQEHDFQIKSSVQ
                     VGNKADSESKEFLGIRYDPNKYPNNIVNINDGKYTLTKEDHEALSEKGSQTFWVNYAD
                     LDQLGRAGDVEALITYDAVNSHSSKNVERPSFKSSVHIAGEYKDGVFDQERDTWVGKD
                     SNNEITQLEGYKGYLYNKSHSLAWSLGGDMEVHNLTLGTRAQNVGKNDQNGGMAYSET
                     IVRDAIYKNKNEKVLYKVDPIYKGNELVPRGSHVEAFSVNDNGKTVNLNVYVFNNQKG
                     ININYQNGTWVRD"
     gene            60593..60940
                     /locus_tag="LP386_000365"
     CDS             60593..60940
                     /locus_tag="LP386_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917635.1"
                     /translation="METISINGLDKSVANRIKKGNGYYLLKKGKYSVARELETMSIVY
                     VAKNHFDVEQAIFDPDSEIGKCVELSEKTVSTKGAMIIEREMLDEIRVIIPKDTQMCE
                     DSISDDEPKSERK"
     gene            60953..62215
                     /locus_tag="LP386_000366"
     CDS             60953..62215
                     /locus_tag="LP386_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917636.1"
                     /translation="MIKKSIELKEYKRSDGEKYYPVASFSKSVYLVGRALIVGAIGIY
                     ILHWVTKVVQLLVDTLVSILVSLNDVNGTDDLGLKEMFKELLNAFFPNYLSYSYNAQN
                     FFAKLHLVDISILVLEAGAVFFVGYLVTLMFRHHYGEQRPFFDDMESRRLKREALEAM
                     DVKYDPNKIIGDETNNKKRKRHKTQLESDVLSTLKNIKISVHTRRDLSVNEDIREYIV
                     KIPQPKGKKVRETVLRQIQDLGSILTRATSGRAKFGEKEDEVSGDYFIFRASVNIERE
                     RKERVSTKNKETEKATSSIAVSNSQFSFPINLFADNSKNIQNQTEKARKYAETQKQSL
                     ELYLSSADVPASLTDMHVGNTSIEYLFTLSRTRKIQLSSMKEEIETYLHISGVIVRIN
                     AGRIQITLPLGENDRIPIDVPSMINSVF"
     gene            62295..63671
                     /locus_tag="LP386_000367"
     CDS             62295..63671
                     /locus_tag="LP386_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HBL1917637.1"
                     /translation="MAMKLLEKVKKRAEKAESILLDKEPNKKLNGKFSVNMLNTKAKD
                     PTDAILGIKPDGTIAHFCISEMPHLLVAGTTGSGKSVLLNEILVTAMCHSTPDELKIG
                     IVDPKRVEFGRYKKLPFMLADPITDMDEAYDFFEYLVILMHERYKLMEKAGVQKITLY
                     NEYAEKNGLDRFPYVILLVDEYSQLVGTHKEVEGLIVQLGQMARAAGIHVILATQSPR
                     STVVTGIIKANFPSRVCLMVASDLESRIVLDEGGGESLSPKGDMIIKHVNGSMVRAQG
                     AYISNKEIETIFNHLRNTMPEPEYVDYRAIVAESRGEGGEDEDFGGIGKAPVRKSAKR
                     NLSTPLANPSSKEPSIEKKSAFAIKLEKNKEEKVEQGAKTLEKLQAEKLEKVLRALGN
                     ADPEPQTSNNTNNKQPITSKTKPKTTDPKVSVNVTITTDNSEKKQVNGTTSPIMQKML
                     KEKKQVHK"
     gene            63668..64297
                     /locus_tag="LP386_000368"
     CDS             63668..64297
                     /locus_tag="LP386_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917638.1"
                     /translation="MIIVSSFLRWLTPYKYTDEVVVKRAKKKDKKAVLTPKQMLDHGI
                     LGVKVLEMNKPFESNSAREKLLGAEADVAYFYHDKSKHQIAIKFNPKSAWRYQARDDL
                     KRRKLRPMLYPEGKEAFDRTHIVPIGFHGTESDNRLLVGWNSNQNRIQINKFEKKVRK
                     FNDLKTILWFADICKQPDGTAKWEAVIFDENGKKVMSETWHDKAKFVWQ"
     gene            64316..64795
                     /locus_tag="LP386_000369"
     CDS             64316..64795
                     /locus_tag="LP386_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917639.1"
                     /translation="MLELFEANRTGFNQKLEVGETIEYKDKNYIIIGIYNTRINRIGD
                     PRITSDLVCQSVNYSPDLTSRYKKYVLLEYRHKITDENSVNNTRNIFKIGTVIPYSNN
                     EEKIFYQIYGIEKFEYEHVDLLVTYQMRLIEPWSQAEIDKAVKLNRLSKFNVLGNAF"
     gene            65297..65350
                     /locus_tag="LP386_000370"
                     /pseudo
     CDS             65297..65350
                     /locus_tag="LP386_000370"
                     /inference="COORDINATES: protein motif:HMM:NF019230.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            65354..65953
                     /locus_tag="LP386_000371"
     CDS             65354..65953
                     /locus_tag="LP386_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HBL1917640.1"
                     /translation="MREKNKNSSRYLVATVVFVCVLIFLFDFLQIGKSIIGNTLSAKE
                     MVALGGLYEGHLFPNIFISIVSHINLYHLISNLLFLVVLEEALNDQYEWLTLLIVLII
                     SGLLGSLVPFLLQSNIVSMGLSGGIFGWIALFAIAYIRFDSKEHLLLSVFILLIIGIL
                     LVSTFESGETNVLSHVIGFVCGMILGFILKNVSLIKQKN"
     gene            65969..66445
                     /locus_tag="LP386_000372"
     CDS             65969..66445
                     /locus_tag="LP386_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917641.1"
                     /translation="MPKKKEKKIPVFLSVSEMLSLQILLRKKIETIDEEVRNKRAMYE
                     QREALRERIHYFDDIHTKIYEARTNNEDESKLGLAQQRIFEWLNTNTEQEPLRAISNL
                     FEFGTKHWFNAVEKDADLQEAFDTLSKDSKSMRDLLITYLNEHEFEQTKTKKKNKE"
     gene            66462..67364
                     /locus_tag="LP386_000373"
     CDS             66462..67364
                     /locus_tag="LP386_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917642.1"
                     /translation="MLLTLLGYLCLILAFFGTIAIIIGQFQTNNPIMRNIGIGIVIVT
                     FIVFNATKIFGSNDKQFGISGVNNSYAPDSLGRVVIDGTFENVTSYKNVSLTVKEDGK
                     KASDDVLATIKPSQSQFEVFYTVKENSPVHKLTLVFNVDGEEYYKDVKINKTSTKKII
                     ESAKKEVATEESTTESSSTVEAELPDKIDFDPEKVKSFESVSGSMADRFNTEVFKAIK
                     TVKLDTEKQMINVTLFNSVESMDQDKKVTVARELGKRVIGLYRGTAKPDSDGADLPVH
                     VVYEDGKVFGDSTANEALTIKLAK"
     gene            67437..67628
                     /locus_tag="LP386_000374"
     CDS             67437..67628
                     /locus_tag="LP386_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917643.1"
                     /translation="MVVNKEKVRKYVTLKIASVKYLEKRAKEEERARGKKVTVSELLE
                     ELIENDQTIRRAFTNRSIR"
     gene            67792..68379
                     /locus_tag="LP386_000375"
     CDS             67792..68379
                     /locus_tag="LP386_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917644.1"
                     /translation="MENNNDIRHFSIGERVTTVSELSKDYRDKEGTIISLNKNRRGVW
                     QYVVDLGDGVTVECKDSQLIRNDGSHSIEKAILVYPKVSSKIMNDWLLGKFGEYNKKE
                     IAEVIGKSYPTVLGYLKKITNKEAKVEDVLTVRELQSLIEYRNKQITNPEYLKKEDGL
                     LKQLEQVNKIRKMQKVAPLSLDNFKKIYLKEIEKD"
     gene            68379..69278
                     /locus_tag="LP386_000376"
     CDS             68379..69278
                     /locus_tag="LP386_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HBL1917645.1"
                     /translation="MWSVTLPFQPVSAPRPSARRNVSDATNDVAEKRISTYYDKKYLD
                     YLKKIKSFIEDQGLLDDEFYSIVNDPMGAIMEVDFYYQIPKSYKKVYNIMKTTAPDLD
                     NLVKSAMDGIFNISAIRDSHITGLIAFKYNVANEGKTVVRIKRYSEFEWDTSEGLNGD
                     IWEATFDFKPVATPRPKSKFRGNGIITYYPKEYNDYLENIKNTLKEKDLVNDQLKKVM
                     NAPMGVIAQIDYFYQVRKDKKKLDSLMRTSQPDIDNLVKGTLDGIFNKEIGIKDSRVV
                     GLIAFKYNTFEKSKTNVRLQEMG"
     gene            69278..70192
                     /locus_tag="LP386_000377"
     CDS             69278..70192
                     /locus_tag="LP386_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917646.1"
                     /translation="MNNNEKILHVLDSFETIQEELKKYRDVLEQRYDFVNQQKSNHMD
                     FILNMNDLKKKLVERKEQEKLIKAYFELGEKEVKKAMELNEDRRVLDQLLEQLLVMFQ
                     KGRIDEDLIEEGLRKYPSNSGIGIVLKAIDEEEIEAFIPPEDFESAMEYIKYYSQGIT
                     AFREFDPEDVIHDLNNLKEWCESYEVDDSGLDYLISIMEIEEEMPDKPDPTDILELIH
                     EARNPIAYISRGYTVLEYYKPYISAMNHLRRVLREKREYRSVLNATNRLEKAVSELEA
                     YYREHYLQAGGMPRNTKANISRYIKKAE"
     gene            70244..70459
                     /locus_tag="LP386_000378"
     CDS             70244..70459
                     /locus_tag="LP386_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917647.1"
                     /translation="MKRDVFELYVLERLEDGMMAQEIIDEIDDMISRFGQLELNDGNK
                     NPVVLKQFWLNNFSYKDFIKEKANTLY"
     gene            70649..70903
                     /locus_tag="LP386_000379"
     CDS             70649..70903
                     /locus_tag="LP386_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917648.1"
                     /translation="MKKEELIDIFQIVERANNMGIMFFDRISLKMDLSVAHQEFNLRL
                     KALLNSDDVNFAHDVVGIQNHIDRENKRMGDGFLPRYSSL"
     gene            71081..72124
                     /locus_tag="LP386_000380"
     CDS             71081..72124
                     /locus_tag="LP386_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HBL1917649.1"
                     /translation="MKKILVGILFTMGLVLLSPSVSAESSISMYRMYNPNSGEHLYTR
                     SVGERDNLKRYGWHYEGVAWQAPTSGTPVYRLYNRYNGEHFYTIDAGERDKISHTGWT
                     YEGVAFYSYNGANRVPVTRLYNKYVNWHHYTLDQNEKNIISRQGWKIEGTGWYAMPNS
                     APNPAPAPSNEKVLNVPVIWQGNTMLCEGASLLEGLHYKGVATNQNLTSFVNYMPRAN
                     DNNPYHGYSGEWRYNVNGTYQGMMPDPVVKWAKNVGGNAVNITGSGTNGIKNEIRNGN
                     PVVTWITYNYATPEFKQMPWGRAVWNGHVVLVDGFKNGAYHVVDPVFGAKWINAGTYE
                     KSFNVTGMAVAVR"
     gene            72299..72529
                     /locus_tag="LP386_000381"
     CDS             72299..72529
                     /locus_tag="LP386_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917650.1"
                     /translation="MNQRRRKRLEEISERLSELKDELEVIQEEEEEYKENIPENLQGS
                     ERYEKAEESVDQLEEAVDGLSDILELIEDIAS"
     gene            72532..72789
                     /locus_tag="LP386_000382"
     CDS             72532..72789
                     /locus_tag="LP386_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917651.1"
                     /translation="MINEDFRSEQKMIDISLIEKLLFSNKYTAKELATRWQISESAIK
                     AYRQNKGSVGWRDWKGISIGKAEDIMKREGFQADNDSKKVE"
     gene            73006..73881
                     /locus_tag="LP386_000383"
     CDS             73006..73881
                     /locus_tag="LP386_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917652.1"
                     /translation="MTTNKRWSELVQNTVKKVMPDGYHFNYIQCSQTTESIYFSILNE
                     NRLYYFRVSSHHRKKREDNVTTFLSGKYNGFKELSEAIGEYLKSNRFVRISDKHILIL
                     LLYLNNSFKLFWRDDTFYYIENGMDIYSGINGILKHYIKALLRYGVLYQEDLSNQIKI
                     SNSGKSLLAKYKKLLSPIYKGIDMEAVNSETLFNLVVDEKFANEFFKSKKIERLNNLF
                     PENAIKAYVDNNKSRLYNWFIPKRLRGKIKIGDQVKVINLNHTKIVTVTELYIAEKEE
                     ITKMKPVIKILDNKE"
     gene            73891..74685
                     /locus_tag="LP386_000384"
     CDS             73891..74685
                     /locus_tag="LP386_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917653.1"
                     /translation="MVAKKNTLKEASEKYQDMKRRGLIPKDKKGIWREFVKEVSSDRS
                     GGDFVGRYTAKGYSRRLRITVEYGTNESATELKQRYLDTRREASKKYDDFKSRGLIPK
                     KKKGIWREFFKEEDSNRNKGDFIGRYTAKGYTKNLGIKVEYGTGESSWELRNRYLNTL
                     LEKYKAELLELFDVNDFIEMAEKYGHEEGFMINDIMVIDNFTDLLALAKKARDLRETQ
                     MYLFRNKNGRNRRTESSEIEDYYDAFTHDLGAFVDEISGVMDKYRV"
     gene            74714..75832
                     /locus_tag="LP386_000385"
     CDS             74714..75832
                     /locus_tag="LP386_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917654.1"
                     /translation="MGNNSIYTPEMQNKIKRLVRLGWMTRGKLDSFSTIKYLLMDIYR
                     QNKQTGIHFLGYDKPEDAPFFVPSSAYRASTSGSMYNLDLFEEGAKMIEYDFNEAYSR
                     IMRNYPLPSNTYLKVKYNTDQAILRAINRPKVRPYENLKTYMFFLVNFEGTAKEGTYA
                     NPKSQSMFADYGENPKTANEPIWLSEIELTLILDYYDIKEMEVLDSHTFLTKKGLLKE
                     YFERIEPLKTDPDTLKLYKNLRTKVFGAIGQKSLREGETSTFDKYSMYNRAYSSMVAG
                     VFRDRMVRYEQKYVHSAYGLLKIRTDGLYFRSEVPEFEELYKLGVVKKKVHTISKEEV
                     EKALEFKNKGFENKGSFGKSKDEVKGVVIDDDFEFDFD"
     gene            75865..76185
                     /locus_tag="LP386_000386"
     CDS             75865..76185
                     /locus_tag="LP386_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917655.1"
                     /translation="MKKKIVEGNVGVIILKDSTDYAKSMALKDEKVARMDKDLVEFLM
                     DDTERLKGDQFLSLMKDKGLNTYGLFDYKKLAIEWVKEGEIFFIEEWEGTENLVLHQY
                     LLKA"
     gene            76315..76998
                     /locus_tag="LP386_000387"
     CDS             76315..76998
                     /locus_tag="LP386_000387"
                     /inference="COORDINATES: protein motif:HMM:NF013235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBL1917656.1"
                     /translation="MGKNDFEVILMSLSVQYHNTMNNIAFKKFSNVEIDVFFAICSQL
                     EEKGSDEVSLSFRQLKELSNLNMMTDSSLVKVLRSLYKKMATLYFYRLSEDGSETCFV
                     IFKEYSIDTSKSNIAIKTNAEYMYLLNDLTSNFTIFEMKEFTSLRSKYSKSIYCLLKQ
                     SNLGKQVINIDEFRKLLAVPKSYKMTNIDKKILEPVCEELSIYFDELSITKVKTGKSI
                     VAFEFTWNK"
     gene            77224..77742
                     /locus_tag="LP386_000388"
                     /pseudo
     CDS             77224..77742
                     /locus_tag="LP386_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321353.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum ABC transporter ATP-binding protein"
BASE COUNT        28897 a        10977 c        14936 g        23207 t
ORIGIN      
        1 acttttgttt cgtgttaagt ttctttatat ccatacgccc cttatgtgta aaatttcttt
       61 attcatccca cgatccatgt tattttatat ttcctttttc atgttatttt tcgtcagaaa
      121 ccgatctagt ttttacctat tcccaaaatc catttattcg ttatttttta ccctgattaa
      181 ggataattat ttgatgctta aattatctaa aaaagcgatt tgttgccgat ataatcatga
      241 tgttaaagct gaattaggcg gaaaggcaaa atgttcgcaa aatcgaagta tcaattatct
      301 tgttttttta taaattttta agtgaaaata tgaaaaattc tcttttaatt ggtataggta
      361 ttaaaattac atttaaccat tcataaaagt atgcgatttc attgtttttt atgagaataa
      421 tataaataaa taacgatata aaaatcattt tttatactgt tttgtaagaa tataaattga
      481 tctaatttag aaaaataatt caaaatttaa atgttttaat attacaaata gaataatgtt
      541 atcgtaaaat ggtataacat agctgaatat tttatttttg ttattttatt agcaggaaca
      601 tctaaataat attacatgaa tccatagaaa tatattggtt tcaccttcag attaatattg
      661 gatcatatta atctgaatat aatatatgaa ctaataaata gcttaacctc gctattttgt
      721 tttttctgat cactacctac acagcattag taaatagaat ttaaaaaata aaaaaattaa
      781 gacaaaaaaa gtatcaacat aaacatatac atatacacgt ttatgttgat acacttaatt
      841 tgtcctttaa aaagcattaa ttattgaatt atgttatttt ataatttgat tacaagctga
      901 ttgctaggtg ttgtccttga attacatttt ccaacggtta ttttatcgtt taatttatta
      961 attatttttg atctaaaaat tagcttaaca aatatataat taaccaaccg ccagataaaa
     1021 atgcgatcat tgctaataaa taagcaaaga taaaaatatg ttcgatcaac ttaaaccctg
     1081 atgcgattaa gcagaccaag taaaatagaa attctcttac agataatggt aattttctaa
     1141 ctagcatact cataattaac accccaaagt aatattgtat tttgaacatt ttacatccaa
     1201 tacagcatca atcaaccatt gccaatcaaa aatgcaaggc ttcattgaag tatgtttttc
     1261 agatgaaaag atataatata atttcttcgg aataatattt tcagttgttg ggatcaagct
     1321 aaatttaata ccatctaact catagctacc agctttctct ccattaaaaa tttccttagc
     1381 actttcttct aaagaatcaa aatatttttc gacagcaacc tttgaagctt ttactattga
     1441 agcatttccc ttttcgataa aatctgcttt tgttttaccg acaataagta attcttgatc
     1501 agtaaaatct tctaaaataa tagtagtgta attcttattt cttctcaatc gcatcaggat
     1561 cactccttaa tataatttat gtttttataa tatcataata agataaattt gcaagtgttt
     1621 atttacacct ttttacttac actttattgt aattgattat acttttttga ttgcattttt
     1681 ttattataaa cagttgcaac tattagtaaa taggtgtaaa ctattttcgt accgaaatac
     1741 cataaacaca aacagaaaga ggtcatacca tgaaagaacc attattgttt tccgttgact
     1801 tagggaataa atcagtaaaa gaaatgagta cacacgtttc tccactctcg cttccctctc
     1861 gtattttgaa caaaaatatc attaattcag gacgtttttc taatataggt tcctcattaa
     1921 aacgatcact aaacgtttct gaatatagcc tagtaaacac tactgaaagc tattattttg
     1981 ggaaggatat acacgagcta ggaaaagatg actacgtgat agaatcacta ggttttggga
     2041 tcagcagata caagcaggaa acctaccaaa atatcctatc tttctcttta gctaacctag
     2101 cacgtttaga agatcaatct gatgacgttt taaccgttaa tctagtttta ggtctgcctt
     2161 catccgacta taccgaaaca atcgtcaaat acgtgatgca acaagccaca cgacaacatt
     2221 cagttgaagt tgacggtaaa gcttataata taaacgtaga taccgtttgg gtactgccac
     2281 agccgattgg aacactatat aacctcctcc ttgctgatga tggtagtgta caagatgaat
     2341 cattgatcag tcagaagatc ggttttgttg atattggtgg tggcacgaaa ctttttgatg
     2401 ttgtccaaaa ttttgaaatt gacgaaaaca accgtgaaca aaaggatacc ggtattttta
     2461 ctttatataa tcgtatcgta aatatgcttg accttccgat cagtcctaat gctttccaac
     2521 ttgaaaagat tatccgagaa ggcaaagaaa aaggcgtata tctatttaag ccaagcggaa
     2581 atgaaagttt tgatatttca gaagtagttg aaagagaaat aaaaacatac accaatatgg
     2641 ttgttgcaga agttttagct acattcaaaa acttcacaac cttagataaa gttgtcttta
     2701 ctggtggtgg ggcttctatt atcgacaaac aacttgtaaa agataaaatt ccgcatacct
     2761 tgtttgttga agacagtgaa ttttctaatg taaaaggctt ttacaagttt ggtttaactc
     2821 aataaaacag cgaaggagat caacatgaat aagggaaaat cagagcgtta tgtagttata
     2881 atcaatagag aaaaggttag cgagttacct ttagcagagt ttcttgaatc tgaatatgaa
     2941 acactaggcg ttaaatactc tcagacgatc aaaaaagctt tgaatctata tcggcgtgta
     3001 aagaacaatg aagttacaat tattgaagca ggcaacgata taaacgatag caaagtagca
     3061 gaagtaaaga ataaaccaac tgatcataac cctattcaac aagagcatcc ttcaacggtt
     3121 acatccgatc attcagcaaa gaaagaaaag ccaatgctaa aagggttcaa tgcaccaagt
     3181 aacaaagact tactttaaaa ataaaaaggc gaggttacaa tacctagcct ttttattatg
     3241 tacaaataca aacataaaca tatacgtata catgtatata aacatgtata cgtatatatc
     3301 cataaacacg tatacgaaat ttagttaagc tatacctaac cgcttgttcc aataaaaaaa
     3361 gtgatcagct ttaaactgat cactcaccaa aaacttcatc atacaagtta tctatcattt
     3421 caccaagtaa agctgaatct gatcgaattc ctaacttttc gctgatttta gatagtttct
     3481 ttctttgtga tggttgaagc gtgaattgat aatttttctt cttttcagaa ctatcacttt
     3541 ttagtttagc aaccaaagaa cttgttgttt ctttaagtgt ttgtttaggt tcttcaactg
     3601 cttcaaccac ttcaggaact tcttctactt cagcttcagc gaatttttta aatctatttt
     3661 ctttcacttc aatcactcct tattcttgtg ccgtatcaat tattttgttg tatagcgtaa
     3721 acgtgctttc aaagaaatcc ttattcttac gatagatatt cttatcctta gcgaactcag
     3781 caatattctt accttctaag ctagttgcat taagcaattc cttctcttgt acatatccaa
     3841 gataattaga taacgttggt accaattcta ggaactcacg acttgaatta gtattatgtt
     3901 tgatcctgct accgatcgta gcgtatttag tttccatcag tgtttcgcca gtcttaatat
     3961 caatcaactg ttttgctagt gaatcaatat ctttaccaag cttcagcaaa gcttcaaaac
     4021 catctttaga tggatcagaa atgcctacga caagatcaga tacagcccaa gcattttgag
     4081 ctagtagacc tgcatcatta tgagtatcaa tcagaattag atcatacttc tctttaagct
     4141 gttcatagtt aacaacgatc catctaaaca gtagggttct gttgttaggc atatcacgca
     4201 tttgcatctc aacttgtttt aaatcttcac ctgctactaa aatatccatg ttctcattta
     4261 tagctaaagg ttcagctgat ccatgaagat ataaatgatt gattgtattt tctcttttcg
     4321 ctttactgaa agcatcagga aatcgttttg ataggttttg cgacttatct tcatcaatat
     4381 acagcacctt catacctaaa ttttcgacag catatccacc tagattgtag attgttgttg
     4441 ttttacctgt tccacctttt tcaatgtttc cagtaatgat tgacaacttc ttttccatga
     4501 ttaaacctcc cttattaacc ttttgtaact ccattataca atataaacac gtttatgtat
     4561 atatttatat acataaacgt gtttatattt atatttgctt ttatattcta caacataaac
     4621 atatatatgt atatgtttat gtatatattc aaatatataa ctattgcatt tgtcatacaa
     4681 tcgtagtaca atgtaattga aaaggagttg ataaactatg ccagtaataa gtattcgtgt
     4741 atctaaagaa gaaaaagatt ttcttgaaaa agttgctgaa ttcaacggag ataacatttc
     4801 tgaatttatg cgtagtaatt ccctgcaaac agcagaaacg ttagtagact ttgccaccta
     4861 caagcaacta atgaaagagc atgaggaaaa cgatcaaagt atttcccacg aagatatgct
     4921 aaaagagtta ggcttataag atgacttacc aagtaagata tgaacgtgaa gctcaaaaag
     4981 cgctaaaaaa aatggataag tttcaggcaa aggttatcct aaactggatc gagaaaaatc
     5041 ttgtaggcac tgatgatcca agaaagcatg gtaaaggtct aacagctaat aaatcaggct
     5101 actggcgata tagggtaggt gcataccgta taatagctga tattagcgag catgaagtga
     5161 caattcttat attgtctatt ggtcacagaa gtgaagttta taagtaacag acaagctgat
     5221 aaggcttgtc tgtttttttg ttaacccaac aaaatcactg tttacgatcc cactttacct
     5281 aaaaaagaac aatatcctct tgatattata cacaccagtg tgtataatat aagtgtaaac
     5341 aagctaatta actttcaaaa ggagcgattt tttatgggat ggtatggtga ttattcatca
     5401 gcaaatgaag tgatcgaaga aaagaaaggg tacgccaaaa atggtttgga aatcgtagat
     5461 accaaagtaa cgaagaccta tggaattatc cttttcaaag atgcagaagg aacctacgat
     5521 attgacagct tcatctttcg agatgaaatg tacaaaccaa tctacttctt aaatgacagt
     5581 cctgcttact ttaagaaaat tccgaaaaaa tggttgaaat tctttgtcgg tgatcaagaa
     5641 aaaatggtta agcgacaact agatagaatt aaagaagaaa gcaataaacc aaaacttgat
     5701 gacttattag ttgcaggtaa aacttactca atctgggatg gatcgtatgt cgctgtctat
     5761 cagtataaac tcaaacgtag ctttattttt cgactacaag atggatcact cactcggttc
     5821 actcgactac cagcaggaga tgttaaggaa gtagcctaaa acttaaatac ataaacataa
     5881 acgtgtatac gtttatgttt atgtatatga atatgaatat aaacgtatta ggtacgaaca
     5941 cttttaaatt cttttctggg ctttgttttt agggtagggc taaaaacatc accatctgat
     6001 ccaaaacagc tcagaaacgc atttaaacgt atctgatacc aatattacag aaggagtgta
     6061 tcgtatgatt aacctatttc ttttagtgac agctagtaca ttattcttta ctggaatatc
     6121 actgataatt tcctatttga tctataagaa agccgaaaat cacacaagca aagcaaccgg
     6181 actagccgtt tcatcctttt taactttgct gactttattt gttactttat cgttttcttt
     6241 tgtttagaac agctgatcca ttagcacctt tttctcttta cattatacac actgatgtgt
     6301 ataatgtatt tgtaaacaag ctaattaact tttaggaagg agtgacaaga tgctaacagc
     6361 tactttacag caacctactc acgttgctat tgcagaaagt tatacaatta atgcagggat
     6421 cgttaaacag ctgatcaagg atcgagaatt caaaaagttt aacagtcggc aagcgtataa
     6481 cagacagcta aagaaagcta ttctaaagca caaagattcc ttcatcggga acttggaaag
     6541 tgtagatgtt aaaactgttt caacggcatt ttcagttgtt gaagtgacta ttgacggtcg
     6601 cttgatttct ctatttgctt ttggaattaa ttgataggga gtgtggactt tggaaggtaa
     6661 gtcttttgca gaaatttgga ctgaatttat tgaagtacca actcgcattg atccgataac
     6721 ttctgaaaag gtattggatg cagacttcta caatctcaaa gcaggtacta gccttgaatg
     6781 cgtttggatg tatttagaag aacatttcaa aggcgtaacg ctcggtcacg tcctatacca
     6841 caatggtgcc gagtgggatg caattggaaa tatccatttt tcttagtaca agaaaggaga
     6901 acacaatatg aattataccg atgaagaaca aatcacttta gaatatgttt tcatagatga
     6961 agaaggggag gaaattgaaa aagtcttgat tatttcatca aaagacttgg agaacgcttt
     7021 gacttatgaa ccatacgaat caaccgtaac tgtcaatgaa ttcttagata cctatacttc
     7081 tgatgatact tgggaaatca tgaatatttg taacgctaat aacattcaat ttgctgaaaa
     7141 aaacaataaa tcattttatt agttttgcaa taaaacatcc tctttttcta ttgattccat
     7201 acacaacaat gtgtataata ggttttgtaa agggagggta gctatgccta agacagcaag
     7261 agaaattgta aaaattctca aatctaacgg cttcaaaaag actggacaaa ctggcagtca
     7321 tgcaaaattt tataattcca agactaaaag aacggtcgtt gttccgatcc acaatggtga
     7381 tgtaccacta ggaacagaag ctaatatctg gaagcaagca gggctttaac agccttgcct
     7441 tcctatttgg tattaggcat actatcctct cttacactag aaaaggagcg aggaaatgaa
     7501 gacaaaaaat attttttatc cggcaatctt cgagaaagaa ggagaagctt ataacatcgt
     7561 tttccctgac ttaccggaaa tatctacctt tggaaatagt cttgaagaag catatttaaa
     7621 cgctaaggat gctttaggat tagcgctata tagtgtacca gatgcagaat ttcctaaacc
     7681 atcagcagtg gaagaattaa ctttgaaagc caatcaagtg gtagtaatca tccaactaaa
     7741 cattaaactt ttccgaagaa gcttaaatac aaaaacaatt agaaaaaatg ttagtgttcc
     7801 ggaatggtta gttcttttag ggaaggagaa aaacataaac ttctctcaac tacttcaaaa
     7861 agcactagaa gaagagttgc ttgaaaagta aaaaggagac cgaacctatg aaagctacac
     7921 acttaaacta tttctctcga acgttaatca ataatctatt aaaagataca actggcatta
     7981 gcgttagtac caaacacttt gccaatgatc taattatttt tgaggataat aacttgcgaa
     8041 ttgagatgtt tattgaacag gcaaccccta actcaatacc tgaattctgc tatacgcaca
     8101 ctgaaaaaat gaaacatgca aaatcagtta aagatgttga aacattaagt gaatcactaa
     8161 cgaacgcttt aaacctcgtt aagaaggcaa aattgttatt tgaatttcaa accgactacc
     8221 acaatgagtt gcttgctcaa tctgaaattt tagattaatt gaaacaggag aagagaaaga
     8281 tgaaacaaac acagacagaa accattaacg atacgcttgc tgatcaatta gcaggttatt
     8341 ataaattatt tgagatgagt aaagcacagc gattgatcca ctatctttgg aaatacaaaa
     8401 ttttgtttct tttttgggaa gcaacactaa cattctcagt tcttttttat aagtcagatt
     8461 tttataatca acacttagtt ttagggagtt ttttgcttat ctacaccatt ttgatgctta
     8521 atttatatac ctacatcaca cttgaagaac acttagtaat tagcgatgca gggatcgaga
     8581 gaaacatcaa aagggtatct ttcaagatca cgttaaacaa gcctaccgat aaaaagctct
     8641 cagaagcgtt ctgagagctt ttgacatttt cttgtataat ttatcctaac acattacaaa
     8701 gcacctaatt cgagcttata tcaagcaaat ttgctattta ttactcaata catatctaaa
     8761 aattacttga tggaaaacta gatacatgat aagcatgaaa agaaaatcaa tttgagcaga
     8821 tgcagtacaa tacatagcaa tttaaaagct ctcagaaggc ttctgagagc ttttaatata
     8881 ttctttgata atttgtcttt cttaaatcca tacgtcctaa aacaagctgt ttttgcttaa
     8941 tatgatcatc tgagaggcat caaatcaact tttctctcaa caaatcattc aaagctttcg
     9001 acagattaat attctcttca gccgctaaaa catttaaata gtgttccaca gtcactgatt
     9061 ttcgatcata attttgcttg tttcgagctt tagcaacttt cgtattagct tttacgacaa
     9121 ataaattaac attctcagat cgcttgattc ttgcatttaa ctcttgaaca ggcgtaggcg
     9181 atggaatttc tttttcttgc aactctaaaa gcaccaagta tccttccaat acttcttgcg
     9241 ccatctcaaa agcatcttct aaagtttcac catgcgtata taagtctgga aaatctggga
     9301 atttaactgc atattcattt cctttccatt cgaatactgc acaaaaaaag tatttcatcg
     9361 cgttgcacct ctctaattaa aaaataattt ttgcttttta gtttcaaaaa aagaatcgcc
     9421 taccaaaaaa ttgataggcg atcacaagct aattaacctc taaaggagat taataccttg
     9481 ctcccaaggc actacatatc ttagcatacg tctgaagcat cttcaaacga gtaagatata
     9541 ttttgcatta acctaatttt ttttctctat aaggtttttc atcaaactca ctagaaatat
     9601 taaactggac agcaaaattg taatttctgc cttttctaac tttagcaaaa tcaatcttca
     9661 gcattgattt ttcattaatt tcctcaactg attcccttaa aacacgtcta tcaaaattcg
     9721 atattgtttt atactcattt tctgttttcg taatctcacg aattttaact atttcaatca
     9781 ggggattctt atatatttca gctttctcaa aatctccttt atttttggcg ataagatatt
     9841 ttttataata catcgccaaa tatttgtata acacgatgct atattttttt tgaaaagatg
     9901 ctaagtcttt aaaaacaaag aacggatact tctttttgat tgagacaatt aagggaatta
     9961 catcttctga aaaactgaaa gatacactat gctcttctaa atcccaatga atccgatcaa
    10021 tagcagatac agtagtatac gtcttatatt tcttgtctag attcgatatt tcataaactg
    10081 cttgtctttg taaagtgtta actatggttt ttagttccgt ttcaagattt tgatcaacat
    10141 ccatgtaatt aataatcgct ttaacaggta aatctactac gcctgttttc tttagctttg
    10201 tgggtgagat ataactgaac agcaattgat aaagttcata cgactttaaa tccattttca
    10261 tgtcaattgt tgctaagaac tcctcattgt actttgtcag ttcatctttt ttcaaaagtt
    10321 tttccttcct tcacgcatgt tttcagttgt taatcataaa ggttcacata aggcaaataa
    10381 ctcgtaattg atttttcgag atatttaaca gtatttttta ttgtgtaatc ctccttatga
    10441 gtagcaacgt aagataggtg attgacaact gattcaaatc ctctatcttt ggataaacga
    10501 tcataaagcg gataaacttt attctgaagt cggctcataa gtttaagatc gcataagtcg
    10561 gcagaactga tcaaaaagtt tttgattagt aatttagtgt atttgctatt catagctttc
    10621 aagtacgatt gattcatttt ctctgtttta tcttctgcgc cttttaaata agcagggtct
    10681 ctttgttctt gcttataagg taccggaact gacatggtac gtgtaagcaa gaactttata
    10741 tttgtataag tatgaccctt cttgataagc tcatagtcaa ttttaaaatc agtgtattta
    10801 ttcagttggg caatcggttc tttaattaca cgtctttcaa agtctcgaaa agctttatat
    10861 tttttctcaa tactaaattt ctttcgtaaa tctgcaatgg agaaaacagg attttttaat
    10921 ctatcaagtg attttgtact ccatgttaag ttatctctat ttgcttcata cagattaaaa
    10981 tctttagtga ataattgaaa aaaactgatc gcatacttgc ttgtcaagtt aactacttga
    11041 tcaaatgtat attgcgtaaa atgatcttct aagttcgtta ataaaggcat aattgaacta
    11101 ctaaatttaa tagatactgc atcagaaaaa tcattgaatt cagtaatttc tagcggtgag
    11161 atgactttgt attcagtctt accgttaggt ttagttcttt gaattttaat gacagattgc
    11221 tgatgcaatt tttcaataac ttgttttaat cttgaatgtt ttgaagaaga tgaactagaa
    11281 gacatcaacg caaataaagc ctttttagat actttgacgg tattattaaa aggcggattt
    11341 ttagggtcaa gatgtcctat agcgtaaaga taaatttttt gtggcatagc atccatttca
    11401 acaatgctat ctacaagttg attcgataaa gtaacagtta aatcaaactt ttttagattg
    11461 ctttcggtag tttcaaattt cgggtttaca ttcttttctg ttattttcat acgattgcct
    11521 cttctttcta agcttggtac gagcttaaaa acttggaact ggtacgattc cattgaataa
    11581 gtatagacct gttttcgata cgttacaaca agaaatgtat cgtaaattta taacataact
    11641 caatgtcagt aaaacacatt ttattttttc caatcaaatt tctttgaaaa tacagcagaa
    11701 atcgctattt tagaacattt tcaaaataaa aatccttttc aataaaatac gaaattataa
    11761 aaattaccaa aattaaaaaa caaatatttt tctagttttt agaaataaat tcacatactt
    11821 tttctttttt tggatatatt cggaatacca catcgctttt tgtccacgtt tgcatcgctt
    11881 tttgtccaca ttcacatcgc tttttgacca tgttcgcatc gctttatgtc caccctaaaa
    11941 tctatttaag attgatataa agcctttttg gaggttgcta aagttttaaa gattaaaata
    12001 tatattataa atataaataa aaggggaagc tgaagcatcc tccttttcct ttttttcaat
    12061 tattcaaagt tacacaagca aaataaactc ttagatagtg ttagtttttt taagattttt
    12121 tatttttaag attttgaaat aagagaggag taatcctcct ttattaaata tctgttaata
    12181 tatctgttaa atatctgtta atatatctgt taggggagtc ttaatctctt gggagagtaa
    12241 gtattaaagg ggtataaagg taacactttt ggacagtaaa ggtaacaaaa gtggacagta
    12301 agggtaacag ttttggacag taaaggtaac aaaagtggac atttgaggta tcacactagg
    12361 ataagacgtt accttcggtt ttcttgattt ggaaggcgaa aaaatagaaa attagattag
    12421 taacaaatct ttgttgactg ttacctttag ttgtgattta atttaggtaa caagcagaaa
    12481 aaattgtttc ctttaattag taccagatta acatgattaa aggagcgcaa aaagaagatt
    12541 ggagagtaat caatgtctca agaagttacc gaaaagatta ttgatagtga tgtagattta
    12601 gtgtcagaac aaacaaatgc aattgtgcgt tataacaatg gtctgaatac aacagctttg
    12661 cgaggattta agcctgttga aatggatgtg ttttgggcta ttttatcaaa aatgaaacgt
    12721 caaggaacag cagaagtaac ttttgatttc aacctctttc gttatttggt caaatacgac
    12781 agaagagaaa aggacagttt ttattctgtg ttaaaagctt tgagtgacaa actaggtact
    12841 ttaacctacc gttttgaaga ttcagacgtc tatgaacagc tgtggctttt tcaaaaattc
    12901 cggatagata aacagaagga aacagttaca attaaggcaa atgaggaatt tgaatttatc
    12961 ttaaactcaa ttggcaaaaa ctttactcgt tttgaacttg ataattttac aaaactaaga
    13021 agtagctaca caaaagaatt gtatcgtcat ctcatgcaat acagaaataa agagtggcga
    13081 aatggttatt gggtagtcaa agttgaagat tttagaagag cattaagtat accttcaagt
    13141 tatagaatga caaatattga caaaagaata ctagagcagg cgaaagaaga atttttagct
    13201 cctgatgaaa acggaataca ggtatttgaa acttttgatt atgaaaaaat ctatgcaaag
    13261 aaaggaagaa gagttgatcg gctcagattc acttttagtg agccagaatc aaacttgcca
    13321 accatttcaa tgcataattg gttagaagaa gattgagaag aagcaggttg taattttaat
    13381 acaacctgct tctttaaaaa agtatgggta acacttttgg acaataaatg caagaagttt
    13441 ttttgtaagc aagtttcagt ctaaataata tttgaaagaa tggctaatct atacaaattt
    13501 taacaactat gggtaacact tttggacaag tcaagaaaaa aacaattttt tttaatttgt
    13561 tgatcgacta aaggtaacac ttttggacaa cacagaataa aaagtccggt gatatcagtt
    13621 ttggtaggaa acatcttaat atctttgtga gattgaaggt aacatttttg gacaagtcaa
    13681 ctatttgtta aaagttaata tagagtaatt agataagttt tttctttttg tctgataaat
    13741 ggataatatt agttatttta ttgctaatta gtctttcatg atgactgaaa tagctaaaat
    13801 aaatatcttg ttgaataatt gctgatactt taagggatat ctaaatttgc tgattgattt
    13861 atttatgtta ttatgatatt ataataacat aaatgtgtta cgcccgaacc tcattttaaa
    13921 aaaatgaagg ggtgagacaa tgaatgctat taattggcat gaatttgtta actatatgga
    13981 gagcttacta gatgatctaa aaagttttag tattgctgat gcagtaaagc atgggttacc
    14041 agttagtaca acgatgaaat tacgaggatt gaaaattcca gatgaaatta ttaagctgag
    14101 aactaaaaca attattgaaa ccgcaaaagt cgttgacaat atgaaccatg aactaaaagg
    14161 caagaaaaca acttacgaga aagattttga acgtttttta aaatctgtta ttggaaaata
    14221 tctaggtaaa aaatctttca gtgaattgag agatgaagag attgtaccta ctccaatggt
    14281 tagcaaaatc cgaaaaaaca aagccgaggg gaattactat cttggtacaa tagcaaaaat
    14341 cattgattat ttggaaaata aagagcaaaa gaaaggaacg aagaaaggaa gataattttt
    14401 gtgttaaata ttaatgggga agaatatacc gaaatgattc aaaatcccga acctagaatt
    14461 accgaaaaaa cgtctgattg tttgctcttt tatgaaaggg ggcagacaaa ctaatggaaa
    14521 aaaacgtcaa ttcaacatct accaaagatc aatacagtat tattggaggg ttgcttggtg
    14581 ataaggataa gagaacacgt cacggattac gcattatgct tgcaactttt ctaggagtgc
    14641 tttttttatt aacaggcttg ggtagctaca tttatcaatt aggaaactat aattattatc
    14701 tcgtgaacaa tacaacacct ataggctctt cattggagtt tgctcgatca ggagcagaga
    14761 tcactatttc agatgtgtgg acagatcaaa acagagatgt aacagtagta aaactcggtt
    14821 actcgcaaaa cgctagaaag ttgttatcta cgcaaggaaa aaactacaac ttatatatgg
    14881 caacaaaaga aaaagatcgt cctaagaagc ttgaaatgag ctatgggatg ttaagtactg
    14941 atggggatgc tttcttattc ctaaaaggta aattagatga aagagcttat caagttttta
    15001 ttgcaaacca agtatcacta atttctggtg atgatacagc tgacgatgat accaaagtca
    15061 atgtgaatga agcagattca gttacaaaag cactttctca atattctatg aatgatgtta
    15121 ataatgaagg agtaatttct tttgggaaaa aagcaaaacc tgttaatact cctgataata
    15181 tcaatttcag aataaatcca tattcagatt caactaatgt ctatcaagga agctttctta
    15241 ccaaagatgg cgatattgat tattcaaaag ttgtagcagt tacaagtaag aataatgttg
    15301 taaataagct agaagatcag ttaaatgctt caaatactaa catcaagaaa attgaagcca
    15361 caaaagctga gtatctggaa cgtttacaac aaaatcctga cgataaagat tcgcaagaaa
    15421 gtattcgtca actagacagt cgaatggaga ccgaaattaa agcaatcaat gatacacaaa
    15481 aattgattga tcaatacaaa aatgctgact ttaccaaaga ttcttttgga gacatgaaga
    15541 cgacatttaa gtacctaact ctgactgact agaagtaaat tattcttatt ttagaggaag
    15601 tgaacacaaa cagatggaaa atagtaccga gttttttaag aatattcaaa ctgaatttaa
    15661 tcatgctctc acaccaatga aaccaccgaa acataagtta gtgggacgtg atgacgaact
    15721 ccatgagttg tcactgatct tgaatagacc ggaaacaccg caagctatct tgttaggtga
    15781 agccggaaca ggtaaaacag cacttgcaag tgaatgggct gaaagacagc gacaagatgg
    15841 aaagaaagta caagtataca aattatcaat cggacaattg cgtgttgggg gagatgatgt
    15901 cctccaaaca cgtttagaaa cattaattcc aagattgaaa gaatatgagc gaattttaaa
    15961 atctgaggac aaagaaaatg aatttgtcct cttcattgac gagtttcata aagttgttag
    16021 ctcttttggg agtggcaata aaattggggg tgattcgcta aaagaaccgt tagcaaatga
    16081 atcacttcaa ttgattaccg ctactacaag aaaagaatat gaaaactata tcaaaagaga
    16141 tgatgcctta gggagacggt tacaaccgtt agaattgaat gaactaaaaa gcgatgttgt
    16201 cgtcgatatt ttgagacaat ggctaaatac atcctctgtt aaagatgatc ctcaggcttc
    16261 ttttaaatta tcgcaaagga ttcctgatga attacttcaa gaaatcgtac aagcaaacaa
    16321 gctttatcgt gaggatttgt ccgaaccggc taaatcaatt gccgtaatgg aggatttgat
    16381 tgcaaaagat cgagtagacg gaaatgctta taatcgagaa agtctattgc aaatatttgg
    16441 taagtataat attcagctag attctgattt tgatatggaa aaacttcaag aggaattaaa
    16501 gtccataaaa gggcaaccgt tagcagttta tactataaca atgttgttta aacgtatgaa
    16561 gcttggattt gatcgtttta aaggtcgaaa gcaaccaaaa gcaactgctc tgtttacagg
    16621 atcaacaggg gtcggtaaaa ctgcaatggc taaagccgtg gcaagaggac tttatggcga
    16681 tgaaaataaa gttctcttag ttaatatgcc ggactacaaa accaaagatg atgcaatgcg
    16741 ttttagacga ctcataggta ctcatgtaag gcatgatcct tctgcgatta ttgtgtgtga
    16801 tgaatatgag aaagctggtg tagaaacact cgatgccttt ttatcaattt tagatgaagg
    16861 taggataagt tttactgaaa gaggatggga tgatcgagaa gttcacgaca ccgtttcatt
    16921 gtcaaataca attttatttg cgacaacaaa tgcaggtgcg gagatgttcg attcgttaaa
    16981 cagatatagc tcactatctc gtgttacaaa caaggaaaat tctaatgaat atagcactga
    17041 actaaaaaga gaataccgaa aagtcgcatc agggatcaaa caagccttga ttggtgaagg
    17101 tctaaagcct gaagttatta accgatttgg acgaatagtt ccattttggg ctttatccga
    17161 acaaactctt ctggaaattg cttataatga aatgttgaag agtgctgaat tagtacgaaa
    17221 acatttaaat atagacttac gtcttccacc taggaaagaa agagtatatg gtcaaaattt
    17281 ttatgcagac gatctctcca tgcacttagt ttttgacatg gcttcacaag aggattctaa
    17341 atcagggggt gcaaggaata tcttgcattt agttgaatct gagtttgaag aagcgattac
    17401 tgaagcaata attacttatc caaacgcaaa aatattcgat gttaagttga gtgaagccgg
    17461 agcgtttgaa ggaaaaggtg attctaatgc tgaaattatt gcaaagcctt ccgttgctga
    17521 aagtaaagaa aacaagattg tattttcgat tggaggggcg tagctatgaa attcaagaaa
    17581 tatttactac aaaatcttag aataaaacga tgggtcgtaa gaggtctagt tattggagga
    17641 gtattagcag ttactttagg cgctcctttt ggaatgaatg atccaactcc tgacaatcaa
    17701 gacagcaaac aagaaacagt tataaataag aacgttgctt atgcggaaag taaaccggca
    17761 gaacaaggaa tgtggacact atatgctcgt atcttaatgg gagataaaga agttaatgat
    17821 agtgccgcta aaactggaca aatgaatttg ttaggacaag gtggtatcag tgccgatttt
    17881 ccttattctg atatttctaa acaaggtaat tcgattgcag ggggtaatgc aggtactcaa
    17941 ctagcatcta ctttagcaac ttatagttac tacggatata ttgaaacagt ctcaggaaat
    18001 gctattgcca gtcaagcatc atccattcta ggaagtattg gtaggacgat tggtagtttt
    18061 atcggctcaa ttagtttaat cctttctaat attgctgaat ccataaatga actccttgga
    18121 aaatttttca tgagtatgaa tatattttct cttatggggt ggggagaagg tggatcggat
    18181 gtatctaatc cggtatctaa agcattaact agcttgctta acaatttggg attaaataat
    18241 gaattattta aagcgatagc aagcttatct atgctctttt tcacagcaat actaggttac
    18301 caaggaatga aattattgtc gaaagatggt gttaactcga agggattatc accagtactt
    18361 gaaaaatgga ttgttcgtat ttttgtattg tttatattct taccagtggc aggatcgcta
    18421 ttgggagttt atatcaacgg catccagtca gcaaaaaaag atggagatat accaacaaat
    18481 gttgtttctg actacatcat taacacaaga ctttgggctt ctactcaaaa tcttgctcca
    18541 tcatctgata ctggtggtga tgtacctgac ggaaagccta catccgaaat caagttcgtt
    18601 gatacagatt atgaaccatc taaaaaatct gcaatgataa gagcgatcaa tactagcagt
    18661 tatgccagac aaaataatga tctagattct aattcagtcg gtatggctct attaaaagaa
    18721 tggtcatcga atgatacttt taatattaat acttatgccg gtgatgttaa tgtcgccgaa
    18781 aatgatgctt atatgggaag agcgcctgct gtttggacag gctataattt aggggatgga
    18841 aaagaaggaa gtgcaattaa gaaaccaacc aatttaaatg gatatatttg gtcagcaaat
    18901 caaaatgtga cagacgacaa tcgcaagcct gatggaaaag gaacagcgca taactttgat
    18961 gctactcaac cttggggcgt tgctaacaat gcaactttta gcacacagtc ggtagcttta
    19021 ttgctccaat cggcacttga tacatcagga gctaagtttt atgcgtataa tatcgctcct
    19081 tcaggaatcc aaggcagtgc taagaatatg tcaacagtaa aaacagaatg gcgtacagca
    19141 tccttagttg gtcatggagc gatgggtaag tttggctcgt ggctagcgat gaacgctgaa
    19201 tcaatcgttt tagcagttct ttacttagca tgtgcttggg cgatgttcaa tgtaaatatc
    19261 gtgaaagcat ttaaacgtga atttatgcgg atttgggaag tagttctaac aggatcactt
    19321 gcatcaggag caggtgtgat ggcaatttca ttaggtgttg ttacaacatc tctgattgga
    19381 ctacaattac ctatctttct gattactttt attcgtgcat ttggtgatac tgctgtggga
    19441 ttcattccta atacattagt tggcgatggc gtagcaaata ttgttcgatc tgctatgatt
    19501 ttaggtgtag gatatctttt agtctttaaa aaaggcgaaa aagtaaataa tttgattaat
    19561 atgcttattg gcttaccact tgaagtagcg tttgggtttg atgaacgtgc taagttatta
    19621 tttggtaata gaaatgatgc tgtgcgagtt gtggacggcg tttctaaagc aatcaagaaa
    19681 agccaaggag ctaaaaatcc ctattatgat ggtggtaaca gctcagtaaa agatatggtt
    19741 gcaggaggtc ttggagcagt tggagcgcaa aaaatggctg aacgtttgaa caatatggga
    19801 gatagcaatg ctgatgctaa gtccattgct gataaagtaa ttcctgaaac accagaagga
    19861 atgtcattca acggtggcgg agttggttca acaatcaata atacctcttt caaagattta
    19921 gttcgtcaag atcaactacg taataattcc caacaatata ttgatcattt aggacgtatg
    19981 gttgatgaaa acggaaactt tgtcgatgaa aatggtgaaa tattaaaagg tagtaaatac
    20041 ggtaaagatg ctaaaggcaa ctttattgac gaaaaagggc gtttggtcga tgaagatgga
    20101 aaccttatag atactaatgg taaaccattg gaagatagtg aagatggtaa tattggtatg
    20161 gatagcgaag gacgtttaat tgatgaaaaa ggtcgcttag tcgatgaaga tggaaatctt
    20221 gttgacgaaa aaggacgcag gttgctaaat ggtgattttg gtcaggatag taacggacgt
    20281 ttagttgacg aaaaaggacg tttagttgat gaagatggaa atcttgttga tgagtttggt
    20341 aataaacttg gtaaacacag cgatggatat aatgtgaatg gcgatttagt cgatgaggat
    20401 gggaatatca ttgagacgag agatgcgctt gtggcagatc gaaatagaga actcgaacaa
    20461 caacggcata cgccaattgc tgttgcaatt cctgagaatg aagatgacga gattacttta
    20521 gatcaaactc atcaagaact gaggaatgaa atgagtggtg aggacgtgtc agacagagtt
    20581 catcgggaat taggagatgg agcatctggt gaaagtcagt caagagagct taacagcaac
    20641 tttgataata gtgctattcg gaatgacaca gcacttaaag gcagagaatc gctaacaaaa
    20701 gaaacggata aagaacaatc agatgtgaag aaaaagttca ttcctactcc taatgttaat
    20761 caaacagata aatatgaaac aaatattgga tcaggaatgt cgaaagacaa tcaatcaatt
    20821 agagaacctg aactgacaaa tgaaaataat agaacaaata attctaaatc tacttcagat
    20881 aattcaggga aatctaatca atcaaccaag aaaccatcaa cagctaaatc agccgttgaa
    20941 tatctatcaa aaactggtaa aaatgtttac acctcagcag ataaagcttt agcaaaagct
    21001 ccaaaaggta gtctagcagg gataacctat gaagctaaaa acgaagctat taaaataggt
    21061 aaaggaacgg ctaagattgc caaggctact gctacaggag catccaaaac tggtaaagta
    21121 gtgaagaaat ctaccatgtc agtcaaggac tatattgtaa aatacggtaa tcaaaaatca
    21181 actgaaaata agtctgaaga cgagtaaaaa gaaggagcat tgatttgctc cttcttttta
    21241 ctttgatttc taactgaaga tgtcaaggaa aatttctatt tatgcaaaaa aattatttta
    21301 aattgtctat aaatgaatta aatatttact gttcaaaatt gtataattaa aaagggctta
    21361 tgctggtaaa gaacagaatt attatctaaa caaaaacttg ataaaccagc atttttagcc
    21421 aataaaaaaa gtgaaataat ttaatggaaa atctctttta atcatctaaa atttatgtta
    21481 ttatgataac ataaagatgt aaatattgag acgtcttttt cttagttaga tcattgacaa
    21541 gtgaacaaat aaaatttgtc gatgatataa ttaacttatt aaaaatatta aaaaggaggt
    21601 ttttatatgt tcgattctat taaaaatttg gttagcggaa tgacgcctga tatgaaaact
    21661 ttagtacaag ttgttttgta tttcttggca ttcgtttttt cgttgaaacc aggattcact
    21721 gcaatgaaat tttttggtga tgcaaaatgg ggagatggat taaaatatgt tggggcgatt
    21781 atcgcaatct ttattatacc tgtaattaca actgttatgc tttacacaat gggtactaaa
    21841 acaggtaatg atttgaacca aaaagctaat atcatatcag cacttattcc agttgttggt
    21901 atctatctag tttcaaaatt tccaaaaaat gaacagttag gttaaaagtg aattgaacaa
    21961 atttggataa tatgccgatt tgttcaattt actttttacc aaaaaactac gctccaagcg
    22021 tagtttagaa gtgagggaag aaagtaaatg taagatggtt tttgatagag aaaaaatgtt
    22081 aactcacgcc gacgaagtat taatgagcgg tctgaaaggt accgaactgg caaagataat
    22141 gaatatgaat gttaaccagt tctatgatta tcgaaatggg agtaaaaaga ttgaaaaagc
    22201 cagacttgaa acgcttatta aattcgaaaa agcatatgta tatatgctag acaaacagaa
    22261 aagaactatt gaccgaaaaa aaggagtttt acaataatgg caaaattcaa agatattacc
    22321 gaatctatta attatgtggc agaaacagtt cctgtagttg cactctcttt gaagccacaa
    22381 ttactcgaag cgtaccaaaa agaagaaaaa gaagcgaagg caaaaaaagc taaagcaaag
    22441 gtatggaaag aattcgatgc gttgctgacc aaagatttac caaagaaaaa ttatatggta
    22501 attgaagatg tacaaaagct caacagtgag ggagttatag atgagggtga tgctattctc
    22561 gattctgaaa agtatgtcgt tctattgaag tcaagtttga attatgtagc tgatctacca
    22621 gaaaaattta aagagaagct attagcaggt gtccgtttta tggatagtag tggtcaatta
    22681 ttagttattc cggatgatcc taatatgttt gaatcagaag ttgaagaagc tacagacttc
    22741 tatagcgcag tagagcaatt agaagtagct actaatggat tagaacgaat tgctgagacc
    22801 ttcaactctt ctgaagaagt tgaatttgaa gctgtagcag aagatgtacc agatgaaaaa
    22861 gaagctcttt ttgtggatga taacaaacca accgaagcag aaaaccaaga agtaagcata
    22921 gaagaaacac aaatacaaac agaaacctac caacaaccaa aaattgatga aaaacccgaa
    22981 tcccaaagtg acaaagaaaa ttatgtttat gaagctgaaa aaatcacatc tgcaagtgat
    23041 gtaccgaaaa acttagatgc tgatttttta gaaaaaaatt ttgaacagat cattgctgac
    23101 aaatttcaac ctgtagtttt agatgagatt aatgaccctg tcgatttaaa cgaggagatg
    23161 ctatccatac ctgagttgaa accattgctg tttttagcta aagagagtat gaacactcgc
    23221 atctctattg ctaataataa aatcaacagt gaattaaata agacgaagga gcaattgatc
    23281 ctcaaaggaa agcaaatgtt agctgatgag cttttgcgga tagaggaagc aacctcatta
    23341 aatggtcaaa atcagtttac aaatacacta tcggttgcta aagagagcta cgaagcagaa
    23401 gcatctaaaa ttgatgattt agtgatggaa aaatccagta tcattcgtaa agattatgat
    23461 atggcgaaac aggcttattt ggatgctgaa ctaaagaaac tagagcaacg gtatgatgct
    23521 gaacatttac cagaagttaa acaacaagaa gatgaatata gaaaagcaac tgaagaaagt
    23581 cttgatcaac agtaccaaga agcaattgaa tctattaaaa acgatgcatt gaaacaaagc
    23641 caagaagcaa aagaagttgt ggtggaacga attatcaatt cattgaaacc agaaattgaa
    23701 aaatcattaa cagacgtgca agaaaaaact ttagagattg tcgaaaaaac aaagtcagaa
    23761 aatgaagctg agttccatga tacaaaagag aaaacaacag atgtggttgt caaatatttt
    23821 gcgaacaaag aagaagttga aaagcaggta gctaacaaca cgaaagaatt agaaacaaaa
    23881 cttgtagagc aacaaaaaac tatcgaagaa tataaagatc gaatgaaaga ggtcaaagat
    23941 ttagcagagg gttataaatt aaatagcgaa aagttggcag aacaaagtga agctttaaga
    24001 gaagacttat ctcgttcccg aagtgatcta gctcaaatgg cagaaaaaac gaaatcatta
    24061 gcagttgcta cagaaaatca atcaagttca aaacgtgatt ttacaagtaa aaagatggct
    24121 actatcattg ctgtcgctgc aatggcttgt ggaacgatct tgggatcgtc ctactttatt
    24181 agtcataata atcaacaagc acaggctcaa actcaaacat ctatttcgag agtggaaaat
    24241 tcgattggga caaatacgaa ctctgcttca acaaatagta gctatgaagc aacaccaact
    24301 acagagttca aagttgggaa agatgttgtc atcagtattg atgggaaaac aactaaggct
    24361 gaagtgattt ctattgatgg agaaaaagca gttgtgaaaa ctccagacgg aaatcagtac
    24421 aaaattcaag ctcacttatc tgataataac taaggagggc tattatgcga gaagaaaaaa
    24481 tagtttatcc agtaattcaa aacaatcaag aaaacataac ctcttctcag cacttacagg
    24541 aagcacagct cgtgtatcag gtaaatgaac taccacaaac gaacgagaca atgagcaagt
    24601 caatatcttt aattggcttg cttattgttg caatagtgat aactgtaggt gtttaccgta
    24661 agttgaacgt gaaaggaagt atatctgatg gcagataact caaactatgg atttaaacat
    24721 aacttacatc aaaaaccttc tgaaacaatt gtcagagttg aatggcttga aaagcatgtc
    24781 aatagcacct attctgttac agcaaaaaga ttaattgtat cagctatagt tgttgcagtc
    24841 gttgttcttg gatcaattgt ttacttagtt tctgatacga ttaaactgaa atttattttt
    24901 gttccaacgt tattaatgat aattggattt cttattctaa ttagccagta tatgtttatt
    24961 gatccatcta gtggttcatt gatttctggt tctattagac tgttcaaatc agtagttaat
    25021 tcagcaagag tatctatggg gaaaaagaaa ccatttcgag gaacagagat tttaaaagtg
    25081 aaacaagatg gaacaatcgt atatcgagat gggagtgtag cattaatgtt caatctagat
    25141 ggggctacat cactaaccgc ttttccagaa gaagttatgg ctcaggaatc gaaatcaata
    25201 caatatcaaa ataccagaga tcgttcctta gctgaaatca aaatcacttc atctcaacct
    25261 cagaatacgg aaagacaaac tcgaaatatg aaaatacaaa aacgaaatgc aaggagtaac
    25321 aaagcagtct ttgacataat agatcagcaa gaacgatttg tatcagaata tattgatggt
    25381 gtgaaaacaa cagtaatcca atatcttatc ttgaaatctc aatctaagat ggtattggat
    25441 gaaggtgtgg aacgtttaga aaactatacg agtagaggac tttattatag tgtcactcag
    25501 ttgtcagcta aacaaacaaa agaaatatta tctgatattt atgcactgaa atagaggtga
    25561 gagattaaat ggaaattatg ggtagatcac aactattaaa tttcaaaaaa aagagaaaaa
    25621 ctaaaaaaga acaaaaaact agaaattcaa aggtagtgaa taataccttt gttagtgatt
    25681 taacatcttt agttggttat caatttacac catcttacat taggacaggt aagcggtggg
    25741 gaacaattgt gaaattagtg aatacttatg gaatgaatag aaattatgga tttggttgga
    25801 tggttaaagc tattcctgaa gtgagagtag aaggggtaaa agcctatcta attgaagcag
    25861 ataagccagt gtcacaaaaa gatcaacaag aaataatgca cgagaatgtt gggggatcaa
    25921 cgaatagtta tgaaaataat ttagaaggaa aaaattcaga tgctgaaatt agcaaaactg
    25981 ttatgcggat tatggatttg aatacagcat ctttactaga cagcatggca aataaaatta
    26041 ttgattggaa gctagaaatc ctattagtat ccgattctcc taataaaatc agcgaacagc
    26101 taattaaact ccaacggttg tatgatgaaa aaatgtatgg attaaagctt atgtcatatg
    26161 gaggagatca acgtgatctg tttgatagac ttttaagtga accaatcggg aatgtctatg
    26221 agtatacgtc tatgagttcg gattttgcag gaaatgatca tgcaattcgt aaaggtttag
    26281 atgatgcgaa tggatgggct atcggcacta tgtctactag ctacgcaagt ggtgtagctt
    26341 ttatggcact ggatgattct tttacaagta aagttttagt ggcatcacac aaaaacgcta
    26401 caattaaagg ctatgatgaa aaaatctcag catcatcact ttgggggcaa ttgattgcta
    26461 ataatgcaat ggcaaatcat aaacgaactt ttcatattgt cttaaataaa tttgattact
    26521 ttggtgatcc aactggtaga acatttgttg ccaaaccttc gttaaacagt gtaatagaaa
    26581 aggttaattt ggctgaagaa ggtcttaact ctttggagct ttttggtaat caaaaggaca
    26641 ttggtgattt atatagacgg aatctcgata aactaactca gattttttat ttgttagcag
    26701 gcagaacatt agattctgca actagagttt tattgaaaaa agaattaggt aacttttata
    26761 taagtcagaa actttgggat attaattatg aagaacgttc gaaacttttg gtgaacagta
    26821 gtgatacaat gccagttctt ggggatttta ttagctattt gactaatgct gaaacaaaag
    26881 ccaaaaaatc tggtactgaa aaagaagtcg atcgtattat tgtattaaaa gacacattga
    26941 gaacagcatt agacagcttc tctagaatgt ttaatcaaag aacgacactg aaagaaatcg
    27001 gtaaaagtga caaattacag ttttactata acttaggtga tctaagagta gaaaccaatg
    27061 ttatggaagc tcaattttta aatacctttg atttcatcac atcacaagca aaaaaagatg
    27121 atattgttat gattcacggc ttcgataagt tatctattga aaccgttggt ctaattaaaa
    27181 aaagattaac aatgcttgaa gaagatggaa ttcgtcttgc ctttctattt gatacaatcg
    27241 gttcaggaga agacaatgaa tacaaagaag atattgaaac agctgatata ttcaatacag
    27301 atggaaaaat ttaccaaagt tttgaaagtg attttaatta cactatcatt ggaaagatga
    27361 ccagtggaga gttaatgaag tatgaaaaaa aagttgctcc tgctagaaaa ggagaagatg
    27421 atcaaaaact ttctgttgat ttgagacagt atttgacaac aggaagaagt aataaatttc
    27481 agatcaggag accagtggat ctgactaata attttgttat tggagagttt attctttaag
    27541 ttttatcttt gattttgagt gtataaggaa aggataagaa aaaacatgta tatttgagac
    27601 taaaaacagt cttagagaac atggtacgtt ttgtgaaaag agaactatag aaatttcata
    27661 aagcgaaacc ttactgagtg aaataattat agcggaggtt aaataatgaa accaaacata
    27721 aaaattttag atcgaatatt tctaggtaga gacacagaag taatcctaat tcaacatgaa
    27781 gaaggatttg aagttagtat aggtattcag aaacttcaaa aacctcatta ttgtaatcag
    27841 ttgtataaaa actttactga tgaagaaaaa gcgagagttt tttttaatga agtcaaaggt
    27901 atgagggaac agtatgaggt ggttgaagca tgaataagtt accggaaaag aaccgtgtat
    27961 ttagattgaa aggtgatcta agccaattta aaatagatga gaatggacaa ttttttgttt
    28021 ggatgcgaca tgagcattgt tggtgtaatc cctttgagtt aaaaaaagaa aatgaaatca
    28081 gaactaaaat tgcaaacggt gagtgggatt acctcttcag gtgggaagat gaatctttta
    28141 tagcaaatga tatggatcat gcatttgtct catttctgga taatacatgg ggtacttggt
    28201 acgattgtta cctagaaaaa ttgggctttc aaaatattga tattgatgct attgaatgtc
    28261 ttaaagaagt cgatcaaaag tatgaagaag aaccctatta tctcttgcaa caaaaattag
    28321 ccaataattc agtgtttcag gtagaaattt gggaaaatga agatggaact tatgaggggc
    28381 tagcgcaaga aatacccttc tcagatagga agagttcgat ttgaaaagag tatatcagca
    28441 atttttatga agtgaaagca agcttacaat atagtaatgg aaaattgtgg ttagctggaa
    28501 ggtatattct agctaaccaa atcttacgtt ttctgggaga gtggcgtttt aaaacaattt
    28561 cctaggaaaa atagttaaca taaaaggaat gaattgttat gaaacaatat ttaaatgaat
    28621 ggaaagcgat agaggggtca ttagtaacgc aaagaataaa ggaattacct gattgcttag
    28681 agaaggatca tttgtttcaa atacgagaaa tgttgaaaaa agaacagttt gatccagacc
    28741 aatttttagt agtcgagtat ccaactattg gagtgtactg ttgtaaccat atcaatgatg
    28801 gaaaatattt tattattcag gagtatggag gacagttaac tcctttctat actacatggg
    28861 aaatgagtga agaaggaatc aataattttc catgtgaaag catcgaagat tcaatttcac
    28921 acaccgaatg ttaattgatt ataactataa aaaaggattg aacattatgt tcaatccttt
    28981 tttcaatgaa atgttttccg ccatttcatt gtttggtgcg atttctattt tattatatca
    29041 aaataaagag agattttaaa gaaagaagag ggaaatatat aaatcaagcg acagtatatt
    29101 tattattaaa tgctattgtg agaatataac taattagttt aatttgaaag taaatatacg
    29161 ctataaaagt gcatcttgtg ttataagaaa ttattttatt ttgtgaacat aatttaacaa
    29221 ttctttctcg gaattgattt cttttcttaa atagtcttca gacttattaa taatattatc
    29281 tattatgtct agatacatat cacttttcga ttcagctaat tcatacaggt tttttaattc
    29341 tttatccttt aattgaaaac cctgatccat agtcactgca tttggatata gaagcccact
    29401 ataatgttta cgtaaattca cttggaattt ctgattataa aagtctaaca gattagaaat
    29461 aaaaggcgga aaattactgt ttttgtaaaa ttgattattt ccatttaggt tgtatagtaa
    29521 tttgttaaat tgctcctgat ttaatttatt gtaaatccat ggtaatactt ccatatcctt
    29581 atctgctaac ctgaatgaac tagcatcggt aagatgttcg atcataaaat ctatgaacat
    29641 ctctttttca ccaaaatata aatattgatt atatattgtt tctaatgttg aagatggtag
    29701 cgaagaaact ctcatttttt gctgaagtat aggatcaagt agactattta agtgattttg
    29761 taattcttca ttgttgcttc ctagaactgc aagtgaacgt aaacggtagt aatattctat
    29821 ttctgttagt acttgttgtt tcggtttaaa atcatttatt gatatttgta aattttgaat
    29881 tgtctcgtct gaaaaatcat gttgtaattc tggatgggta gctataaaag taagtaaaaa
    29941 gacccctttt gtatatgtga tctgttgatt ttcaccaagt gatttattaa tttcctctct
    30001 tgattcagct gtgaacctat actttgaaat ttcttctttt agaattttta aatagaattc
    30061 tttattatca aaaattaggg cattaagtag tctgaaagta ctttccctat ctctatctgc
    30121 ttcctcattt ccataaggta attgaaaaac aaacttaaag gctgtcttac ataggttttc
    30181 ttttgctttt tcgcttagtt tatttagata gctatttttt agtgcagagt gaaattcttc
    30241 aggggtaaca gacatagcat gtatgcgact tgcatattgt ataatttcga tcgttacttt
    30301 ttttcctaat attggatttt ttaggaatat aatttcatag gacttccgta taacatcctg
    30361 acaagtttct tttgttatat ctcttaattc ccaagtatta ccgttgtaag tgactacagg
    30421 atgagctgaa taatttcttt gatccttaat atattttaaa tcctcatatt catagctatc
    30481 aattagctca gttgaactat aagctttttc tagtagttcc atttcccatt ttggagaatt
    30541 tggatcactt tttcttaatc tagctatatc ttctaaaatt ttcttagaag taatatcctc
    30601 gtaaatattt gctaaatcag ataatttatc aattaaatct aaaacaagcg cactgtaatt
    30661 gacagctatt gcagaacgat aatttccctg ataaaaacta cttcgaactt cttctaataa
    30721 tggaataatt ctaggatttt taactttttt tatttcatca tctaatataa acatataaat
    30781 ctcctttttt tgtttgtatg acaagtttac cataaaaaaa tattaaaaag cgagacaaat
    30841 ttatgttatt atgttatcat gatagcataa atatatagag cgagatgatg gaaaaatgga
    30901 tttgaaacaa tcgttttaca tctggttata tcctgataat cctatgtcaa taatggctga
    30961 tatttttgta gttagcatct tattgtattt attttattta attttctttc acaatttaat
    31021 cgggtacatg attcttgatt ggaaaggaat gttcgatata gagagaaaac catttgctaa
    31081 caatcaaacc tataccgtct tcgaaagtgg agattgggaa gaaaatgaag ttgatgtgat
    31141 ccatgaaatt ggattagctt tatcaggaat acaagatgct gatgttttgg tatcaatgac
    31201 aacggatact ggatacaacg cttatgaggt attttatctt atgtatttta tatggcgtga
    31261 tggtcaagaa attatcaatg gtcgtgctga aaaaacaatc atttctaata ctgaaatttc
    31321 tttctgtatg ggtgaagggg aaatgattgt atataaagat gggtcagcaa acattaaaac
    31381 agcctttggt gatattgaaa caagtattaa ggaacttagg gaatatgtgc agaacccata
    31441 taattttcaa tatttagcag gaagaataaa tttagtttag gagtaaaaat atgaaaaaaa
    31501 ttataaatca accaacaaat cacttgataa ttgaaggtgt tattttcgta acaatgtatt
    31561 ttactgtagg aaatggcatc tcaaatacaa tcattcaaaa aaatccacaa tacctattat
    31621 ttagtcttta tgcttggatt gtacaaatgg tttgggtttc catattgatg ctgttgtttt
    31681 attggatagt acgggttatt cttttattgt taaacaaaag aaaaaaggat aggtgaataa
    31741 aatgaaatca actaaattga aggttgtatt gttatcgaca gcagcattaa taacccttac
    31801 agcatgtggt acaactaata gtgctaataa taacaaagac acaaagtcta gtagtacgat
    31861 ggttactaaa aacagcacta catcggcatc aacaacaatg tcttcaatga ctgaaaataa
    31921 tgctgaaaag tatcaaaaat acgaagacat taataaagat caaaagccgg atgaagttta
    31981 taacaacttt attaatacgg taaaaaatga tgaaaattat gggaatgatc cattgcaaaa
    32041 taaaaatctg actatcgttc tttacaaacc tgattgtcca gattgtcaaa aagcagaatc
    32101 aaaaatcatg caagaaataa aagaaggatt tagttatgct ccaacattaa tgcatgatat
    32161 taccataaat aaaccagctt acgagtatta cgcagttgct gtagatatta ctgatggtgt
    32221 acctgagtgg gtacaaaaca ttcctggtct ggctgatgag aacaatcaat atcatacgcc
    32281 aacagttgca gtagtaacac caaagaaagt taacggcaca ctatactggg atgtaatggg
    32341 aatgacaaca aatacaactg atgaaatgat tgaaagtaca actaaatatt atatggattt
    32401 gggagcatat aaattatatc aacaatcaga acctgttatg gacgatcaat ccaaagttaa
    32461 atagttcttt agggcgtaag ccctattttt ttaaaattaa gtgataacaa ataaatgatt
    32521 tctgaaacaa acgttcttac tcaactactc gaaacacaca agctaattaa ctagattata
    32581 aaggagaatg cgtaatgaaa gaaatcagtg caaatgaagc tcatattccg caaaagaatc
    32641 aggttggtat atataaggtg cttcatggtg aaggaattta taaaatacag ttacttaccg
    32701 gttacaataa cggtgcaaat gggaagtggt taaaggcaac aagtattcgt gaacttagaa
    32761 gtgaagtaga aaaaattagg cttggtctca caagtgaaga aatagctaaa ctgaagggaa
    32821 ataattcttt tgtaattgaa aaagaaaagg aaaaacatct actttatcgt gagctgaaaa
    32881 ttgaagaata ctatgaaatt gatttacctg aaaaattaag aattattgat caacgttcag
    32941 aagaaaaatg gaaaactgaa atatatccaa gcttaaatga ctacaagaca tcaggaaagc
    33001 ccatgtataa ctacacaggc tttttaacct acacacaata caaatatgcc tttcgcaaat
    33061 taaaaggcat taaacaagct gaaattgccc tgtatgagat gaaaaaagtg gatagattga
    33121 aattgattca agatttagtg caaaatacat ggaatcaagc gattgtcgag ctagaaaaag
    33181 aaaatgggaa aattttaact aataaatatc tgatcgtaaa tgaaattgaa gaattaattg
    33241 gtttattttc atgtgaaaaa ggtgaagtct tcttgaagtc atcaccaacc tattcaattt
    33301 tggacagtcc gtatcagttt atacaggcaa ggagatgagt tagatgtcta gcttgaaaga
    33361 tgactatatc caagcaaaac aagagtatga aaaaatacag atgttgaaat ctgagaaagt
    33421 cgaattattt ttaacacaaa aattagcaga ggatcatatt gctaacttag atgctaaaac
    33481 tttagaggaa tatgatcagc agtttaatca gatacatcac aatatcattt tgcttgttga
    33541 gcaggcaaag cgaaggtttg aaaaagcgga atatgatcta ttagatcaag gaattgtatg
    33601 cttggataag ggattgcgaa gatattatgg tgcagagtta aaaaagcaaa atgtagatag
    33661 aaatgcacta aaacatgaaa tcttagaatt gataatgcaa cgaatttgaa ggggtagaaa
    33721 gcaaatgtca caaaacatta gtgctgtaaa acaattaata gaagaagatt tagagaccac
    33781 agttcagaga ttagcggaac gaattcattt tgcaaattat caaaccatct ctaactggtc
    33841 aagcaggaac agaaatccgg aagaaattcc aatgaaattt ttttatcgaa tcggaaaaga
    33901 atatggtgtt gatccgataa aaattttcga gaagaccatg atttattact atcatggaac
    33961 acctaacgaa gtgttagaac atcttttgga agaggcaaaa gaaaaatcat caatattaga
    34021 gctatcgcaa aatgacaaag ttattcaagt gaaatgcgtt gatccaacag gaaagattat
    34081 tgtcggtttt gatattgaaa gaaaatccaa aatagatttt attactcaat taaaaaagat
    34141 aaataattta gatattctaa cgcttagacc agatcatgaa cagttgttta tgagttttaa
    34201 aaaacaattg aaagaaatac aaaaaagata taacaaggtg tttcctaatg cgtgaaaagc
    34261 tcaaagaaat cagagttttt tggataatta acaaagaatg tatcatctta tatactcttg
    34321 gatttctcag catgatcttg ttttggtggt tatatttaaa acagtaattg gagaggggca
    34381 agaggatttt tatcaagata aggatgtgga aactgcatgt ggaataatag attaaaaaca
    34441 ggattgttat taatagttat ttcctgcgct atgatgattg gtatgaggat acaaagggaa
    34501 caatcctatt ttgaagtttc tgctaacaac gtaatagaaa aatgctatta tggtcaacat
    34561 tattggagtg aggaagtcag agaaaatata gatcgtgaat atgttcaaag aattgtttgg
    34621 gatgcatatt ctatcaaaga ttatcctaaa agtttaacga gtagattatt ttacagcgaa
    34681 aaagataatc aaaaactctc agatttgatg atgaaaaaag taagtaaact tgcacaaagc
    34741 tatttggaag aaaaagcagg agcaataaaa gataaggaag aaatggagaa atttgctatt
    34801 gaatgaagaa acggaattat ttataaaaaa agtgaacttt cttgtagaaa aatatttttt
    34861 cacaaagcac aaaattatgt atctaataaa aggattgatc ggtggaatta ttttatggat
    34921 acttactttc ttttctttat ttggtggatt tactaattat aaaaagttag tagacgaaaa
    34981 tgtgaagcaa attagtgcat ctgaatcatt aagacatcaa gctgaagatt tagtaagtaa
    35041 tccattattt ataggaggta tggtagaagt gataataatt agcttcgtta ttggttattt
    35101 aggtatgtgt atcttccaga taatctttga tctaataaga ggaaaagtct ttcaaggatt
    35161 taaatctgaa aaaataaatt tacgttagag ataataggct atgagaggag aagaatagtg
    35221 gaacaaacta atcatattac tgaagaaact aggaaattca tttgtttaga atcgttttat
    35281 tcggaaggta ggtattgtaa caaaggtgaa acttatacgg catatcctat tgaaggggga
    35341 tttaaattag tttttgaaaa cggagacatg aattttacca ctgagttgtt tgagtgtgtt
    35401 gttgaaacgt ggtcagatgt gttgcttgaa gtcactaaat aatcaatgtt atctagtaga
    35461 attaagcaac taaaaaagaa agaaggaaga aaatatggcg tatgaaaatt tacaattagt
    35521 agcagcagga gttagtggtg atatatatct tgcaaaagca aaagatggaa ttatggacac
    35581 gaactataga agagttgcga cagatgatgt gttaagctca gcgacagaat ggtttcgaac
    35641 taatgaagaa tctgctgttc actttaaagg aattgatgga aacattcata gtttgttcta
    35701 tacaaaagac aaagaaaaag ccaaaaaaat tcttgatatt ttgaaggaaa gttagttaat
    35761 taactaacga tataagagaa ggcgagacca agtatttgct tggtctctat cattttaacc
    35821 actagtcaat taaataaata tcaaaaatga gtatggctaa ccacttgatc acgaacagca
    35881 tcgctacaaa tactgtatca gtatttgata gaatacatat tctattttaa aaaaagaaaa
    35941 gaaatttatt gatattatac acatcggtgt gtataataaa gaggaagaag tgattagaac
    36001 tttgagcaat tcaatcattg ctttcgtagg agaataatag aacagctcct aagaaatccg
    36061 ttgttcagta aatttttgag taaaggagac gttatgagca aatacaaatt tttagacata
    36121 aatgttggtt ctgctttttt gattaatctt gatatgtttg aagcttgggc gcaatcatca
    36181 ggatataatt gggcatttag tgatgatatg atcgagtttt taagtcgaac gatgagttgg
    36241 gaaagttata aggtcaagca atttttagat gtcattgcaa aaccaatcta cacatctgct
    36301 gatgatcact ggtcaggcag agagttggca acccttaaag aactagcaga gtacaacaaa
    36361 aactacaata ttccgtttca agtttcttac actacagatg atttttccgt tatttacgca
    36421 ttaggtaagg aaagtagata tttaatccct aataggtact tagagataaa gatgaatagc
    36481 gattatacca actatacgct aggtgaatta aaagctctta gacagagcga cagcgaggaa
    36541 tttagcacgc tcaaaaatga agtaagcaca gagaattttc gcatatcaga tattgaagaa
    36601 ttaaaaaaac agcaaaaaca gcaactagaa aagcaaaaaa aattaattga agacattgta
    36661 aataaacgag tagatgagct tgcagtacaa gaagctaaaa tagaaaaatt gcgacaagaa
    36721 ctctatgaaa aacagcaatc aatgttagct gaagcgaata aaatgcgctt tgaattggag
    36781 aaaaaagtag aagagttaaa tactaaaatt ttttatttgg aaactgaaat tgatgcgatt
    36841 gaaggctatt ttggtgaaag tacaactttt gttcagttgc gttcaggtca aaagagctta
    36901 tcggaagatc cagtggtgat gtttcaaaaa gtacggtatc tagatgaaga attaggaaga
    36961 tatttcagta tgcgagaagt tgaaggtaca gctgatacca tgctgacttt tgagcaggcg
    37021 ctatcctcac gagatgattt gtttgattta ttctcaccga acaaaaagtc aatctcaatg
    37081 atacgtattt ccaaatcagg atatggctac actaacggtc aaatggaaag tacaaacatg
    37141 ctagaaaagt ataaaaaata tcatggagaa actttagcaa ttttactgag aaacggtgat
    37201 aacttatgga tttgttggtt ggatgaaaat aagatcagtt tcaaagatga tttgttttac
    37261 caaaacaaag taacagagca ggcatctgaa accaaaaata tggtaaagga gatagattgg
    37321 acacatactc gtaatttaga agagcgattg aaagatgcta aaaagcagaa gaaggctgtt
    37381 agaggagagt ttgctagtcg ttatattctt ttttcaatct tgcaaggtgt tctagataat
    37441 ggaacgatga tgaccttacc agaaaaagta aatgtgatcc aagcaattaa tcagaaaagc
    37501 ccatatttta ttgcaagtgt ggcggatgga tggttagaag acacacgctt gccgtcattt
    37561 agcgagttga ttgataaata cagtttctat aaagaaacag gtgaagacag agtattagaa
    37621 gcggaatatg agctgaatcc cgataaattt gaaaatatga gagattatcc acacaaacaa
    37681 aatgatgaca tttatgtgtt ataccggtta cgtgggtggt cgcctacatc agcaaattac
    37741 agttattaca acagtgataa ccgttcaaat agtgagagtg gacgtgactt agcatattcg
    37801 attgacttga aagacggcat ttatcagatt aatttagtaa aacagggaaa attccacaaa
    37861 caaatgtttt cccgaacgtt tgttggagtt gattctacta caggcgaaaa tatctatgat
    37921 tactattatg aaagagaaac agagtactat attcgaggac aaaaagccta caacaaaagt
    37981 gactattggg gtgacaaggc gaagcgatta actgcaaatt ttagagtgta tgaatccgaa
    38041 tttataaact taacctttct taatagtgtt tttattgatt atgtaattac tacgaaacgt
    38101 attggaagtt attcaagtac ctacgcatcc ttagttccaa tgttaaactc gatgagccgt
    38161 ttcttaaaag aaagagaaga gaaagagcta cagtatatca aagaaattat gccagatttt
    38221 gaaatgcacg aatggcaaat tgctttatca gattggaaat tgacgaataa ggttcgtaga
    38281 ataacacctt ttcaagccaa gcgctttttg aaagctatga aatttgttaa atagaaaaat
    38341 ccaccagaca agctgatgga aactccccca attactaaca gttgtaattg gtgttagctt
    38401 acaagttaat tatggtgttt agtcaatccc aaattgtgaa acgacaccga taattggaaa
    38461 ggaaaaatga aatgtctgaa gatttacgag agctgaagtt acgaaagaag cagtatgatc
    38521 agtatttttc cggtttgttg aataaacata ttgaagaagg acttgatcat gattttggaa
    38581 aagatgaata ttgtttgtat tgcgagcgtt acaatgaaaa aatgtctgaa tatctacagc
    38641 taaagaaaga gatacagaaa ttagagaaaa aagtacatgc ttggaagtat aaagattcca
    38701 tgtctggtta tggtgaatct caaaataagc caagaaaaaa gaagcaagcg tatgttctaa
    38761 agatggtaaa tggggaagag ttaattgtat tagcttacag taaagaagag gttcgagaac
    38821 tcgttgaaac acctgtcagg aaaaagatag aaacaataaa tgagatagac gacagccaat
    38881 acaatagcat ctatattgaa acaagtcatg gtggatataa gaaattagca actttcctta
    38941 gaagttctaa agttgggata atttctaaaa aagacataag tgctgttacc gatagttttt
    39001 gtactttgtc tgttcctaaa gcatattttc aatacaacag taatagattt gatcgattag
    39061 agaaattctg tagaccatat actgtattga aaactaaaaa attcaataaa actaaaagag
    39121 tttcaatcaa gttaccgact ggtcaaatct cgctaggcga aaaagattat ctgataaaag
    39181 taggaaaaga gttaataatc aaagtgccgg aacgcttatt taaagaaaat tttgagatac
    39241 gtgaaacctt ggtatggaaa gaagaataat agtttggaag acatagcagg gtataaggag
    39301 gaattaaaat ggcagtaaat agaaaattgc aggtattgat tacagacgac tttggcggag
    39361 cagagtggtt tgatgtgcag tctatagatt ttgaagaaga agtcatagtt atagaaaatg
    39421 tatacggcga agaatactca tattcgcttg aaggagagaa tgttgaggat ttacggttga
    39481 ttggtgagta gaaaatagca gaaatatcaa aatggagatg aaatcagcgt gtatatgatt
    39541 gacaagaaaa caggaaaacg tattttcagc agtaaagacg aggtaattcg ggatttgagt
    39601 gaaaactttg caccaattga attatttttc catcagttaa atctagaaat tgaaaaatta
    39661 ctaaaggaac ctacagaatg taaatggcca agttaaaatg tagaaaaatg gccaaataaa
    39721 aatgtaggtt tatgcgtcat ctggtacgct ttccttgtgt tattttattc aaggaggaaa
    39781 gtgtattgag aaaagatatt tatgaaggag tgttaccttt cattatgact catacaaaac
    39841 ctaattatgc tgctctagct aaacaataca attgcgatta tcgtacagta aaacgttatt
    39901 atgaagctgg aataagcaat aaattacctt tacttgctca aaagaataaa aacaaaaaaa
    39961 ctttggttag tgattttgaa gatattatcg ctgacaaatt agctttaggt tgttcttctt
    40021 ctgctattta tcattttatt tctaaacgtg gctatcgtgg aagtgcacga acactgagaa
    40081 gatattgtcg caatatcaaa gcagataaaa tacaaaaagc aacgattcgt gttgaaacaa
    40141 ctcctggctt atctgctcaa gttgattgga aagaagacct caaattagtc aataaattcg
    40201 gtgaagttat ttcttgtaat atcttccttt acgttttagg atattccaga attaagtatt
    40261 tagaactaac ttttgatcgt tctcaaacta ctttatttcg ttgcttaact aatgcttttc
    40321 aatacaccgg aggtgttcct acagaaatat ggtttgataa tatgaaaact gttgttgacc
    40381 gtagtcgtag tcaattttct aaagttattt ttaatgagcg gttccgacaa tacgcgaaag
    40441 aagcaggttt tcttccaatt gcttgtcgtg cttttcgacc tcaaacaaaa ggaaaagttg
    40501 aagctcttgc acgaacaatt gaacgaattc gtgtatttaa ttatgaattt gaatctactc
    40561 acgaattaga aaaaattatt caaacaatca tggattcatt aaatactgaa gaaatttctc
    40621 aagcaattca tgaatgtcct agtgaccgtt ggtcatacga gaaagaacaa ctatcttctt
    40681 ttgatgcgaa tcaacttaaa atttatgctt ctgttgaaaa acaaattaaa cgaaaagtat
    40741 ctaacgaagc gatggttcaa tggaatcaaa ataaatattc tgtgccagta aattacatcg
    40801 gtaaaattct tacacttcgt gtaaaagaag ataaacttta tatttacgat gactctactc
    40861 ttattcgcac acatacgatg actcatcaat tgcttaatta tcatcgaaat gactatatag
    40921 aaattctacg ttctgacgtt tttaaacatt tagaagacga agaattagaa cgttttgttg
    40981 atgaaaattt acaagcgtat gacgaattat agagaggtga atcattatgt ctaattatta
    41041 tcatttacta aacaaattag aagatttgaa tttaaaacat acgagagaaa ttttaccaga
    41101 atatctcgat accattgttc aagaaaatct tagttttgta gaagctttaa atcatttaat
    41161 gacggaagaa ataaactcac gaaatgaacg acaaaaagaa aatcgtttaa gaaaggcgaa
    41221 tttaccgttt aaaaaaacaa tcaatgactt tgattttgga tttcaaccaa agattaatcg
    41281 aacagagatt ttagatttgt gtaccttacg ctttatggat acaaataata atatattgtt
    41341 tattggaaat agcggagtgg ggaaaactca cctagctatt gccattacac tagaagctat
    41401 aaccaaaggt tattcttgcc attttgcttt aagcaatgaa ttagtcaatc gactaaatcg
    41461 tgcaaatcaa cgtggaaatt tagatcgatt gttaaaaaaa tatgcttctt acgatttact
    41521 aattattgat gaaattggtt atttgccttt tacccctgac ggggcaaagt tattctttca
    41581 attaattaat ctacgctatg aaaaaaaatc aaccattatt acaacgaata ttcctttgtc
    41641 tcaatgggct gaaacttttc aagataaaaa attaacaaat gcactaatcg atcgattagt
    41701 gcaccacgct aagattattc aaattactgg aaagtcttat cgaattaaag attataaaga
    41761 aaaaaagttg tcgtataagt aaccttgtta tttatgggcc aaaaacctac atttttggtg
    41821 gccaaaaaac gacatttcta aatggccaaa aacctacatt tttgaatggc cattgacata
    41881 cagaaggacg aattaataaa gtattgaaat taatagcatg taaagatagt catgcttaca
    41941 tgctttatcc aaaatggtat gcagacaaaa atatagctaa aataaacgat tatctagcta
    42001 gtataaagga acgcaatgca attaattaac aatagacgaa aaatgaaatt aaaggagata
    42061 ggaaaatggc agaagttaaa tttggatcaa aagaatggtt tgaagagtta aactcaatga
    42121 ttcagtttcc agaaaagttc actttttact acaacaaaag agacaatatc attcaagtag
    42181 ctttacttga aactaaggga agattagaaa atactcgatg gagtatgata aaaccatcag
    42241 cactcagatt tcatcctaaa gacttgacag cggttgtggc ggtaaaagag gttcaagact
    42301 cacaagaata ctatgaagta gtaaaaaatc tgaaggatat ctggtgtaaa taattctaaa
    42361 ttgaccagtt atttggtcaa aaatagtatg tgattatttc atccaatatg gcatcataat
    42421 tggtatgaaa ggggataaat tatttgaaag aactagaagg tattaagaaa agaaatcagg
    42481 aaagattgga actgttaaat gaaaatagaa ataggatgtt tagttactat gaatccatga
    42541 ggtgtttaaa taaatctaga agtgaaatta tagaatcatc aaagtataaa caattgatgg
    42601 aagagagagt ttctctcatt caagaaatag aaacagagtc tatttttcca gatcattttc
    42661 ctaaagtccg attttataat taaacattaa caaatgaaac gatgctaaat aggcatcgtt
    42721 ttttatctat ttgttaaatt tatttattta caaaatgtgt atcggtgtgt ataatatatt
    42781 tgtagataag ttaagaaagg atgatctgaa atgaaattag aaggtagctt acaaaacaga
    42841 atgatggaag gcagaacaac aaataaggag attgtagttg gtatgggagc aaccgagctt
    42901 ctatataccg acagaaatcc ttatacagtg attgaagtaa aaagcaaaaa cagaattttg
    42961 gttcaagcgg atggggcaat caataaagct acttttccag atcaagagtg ggaatacagc
    43021 agaaatcctg aaggtcaaat attggaatta attaagacaa aaaatggatg gaaagtgctt
    43081 aaagaagata ctcattttta tataggtgat agagaaaaat actacgatcc tagtttttaa
    43141 acaaactgaa gatgagcgag gttttatcct cgctcagaaa ggagtatgaa ggatgttcag
    43201 tcaagaagaa atcatcagca aatcgcaacc ggataaaaat ggaactataa ccatgaagaa
    43261 aaaaattcct tgctatcgtt gtagcggatc aggtcagtac aagtttatgt ctatggggaa
    43321 aattacctat ggcacatgct ttaagtgcga tggtgacgga tttcttgttg taactgaaaa
    43381 atcatttacg ccagaatata gagctaagct aaatgcttta aataaaaaaa gggctgatcg
    43441 aaaaataagg atcacaagag agaaagaatc tcagaaaaat tttgatcgtt atggttttga
    43501 aaagggttat atttacgtgg ttatagagga aaatagctat gcgatcaaag atgaactgca
    43561 tcatcaagga gctacttatg atcctttatt aggttggttt ttcaaagaaa aacaagaaca
    43621 atacaaaact caaaaagttt ttgtagaaga attttccgta atcaatgatg aaggaattat
    43681 tgaattgaag ctagaagaat acagcgaaag acaacaggag attttaaggg cgaagcgtag
    43741 agaagagggt gagtttattg gtacaatcgc tcaacgattg gaattggatt tgaagcttac
    43801 caataccgtc accatagata cacaatgggg caatgtttat ctgcatttat ttgaagataa
    43861 aaaccataat tcattgattt ggaagacaaa taaatttctt tattatgatg aatgggatgt
    43921 tggagaagta aggaaagtta aagcgacaat aaaagcgcat gactactaca gagataccaa
    43981 gcagacttgg gttaaaaatg ttaaaattca aaaaaatgag tcagaaggga taaaagtatg
    44041 aaaagagagg aatacaaaca aagattaaac gaactgcttg aagaggacga aacgttaact
    44101 catggttcgc ctgatgaaat tctatacatg attgataata tggtgatctt tggtggatat
    44161 gaacttggta ataggtcagt tgatcataat attttagaat ttgatgatgt atcatgggaa
    44221 gaaattcttg attggggaat tttggcggta cctgaaacta aaacctatat tagtgacact
    44281 atggttcctt tttttgagga attggattat aaaagacttc ccaaaaatga aaatcatata
    44341 ctgggaggaa actaacaatg ttaagtgact tatttatttt actgatctat ctaggtgtaa
    44401 gtgaaattat tgcgtatttt ttgtttgtca ttgctaatta tggtatttcc agtgcaatcg
    44461 ttcaaaggtt tagattacca gtaagtgaac taaaaaaaag atgagattat cagcatatct
    44521 tttaatgttt ttgaatgtgg tcacgttaat ctttgtagta atcggtgtga ctttcgattt
    44581 aatggaatag agggaaatct ataatggaaa aaagagtaat gattgtttaa tcatcactct
    44641 ttttttgtag ggaaattgaa atatgtggag cttgtattgg tttagttagg attgcttggc
    44701 tataaggagc tagttcttta tcaaaaccat caaagtaggt tttcagtagc gatttaactg
    44761 atcgctcatc ttgtttgatt tggataattt cagcatccaa atcggttgtg agatcaggag
    44821 cttttgatgc gattacctga ttttttttat cttccaactc tcttaggctg tttaacaagt
    44881 tgtaaaaaga atcattttga ttgttcattc caacgtgagt tgcaatttta acagaagttt
    44941 cgtccgtatt gtcatcaaaa gaactcattg gaatatcaag tagtaacgag gatgtttctt
    45001 ttactgactt tttctttaca gcattttttg tttttccatc ttttttgctc tttactcgag
    45061 atgtttttgg agctagttta ggtaaatcac ttgttttatc agtcatttat tagcttttcc
    45121 tttctattaa tttatgttat tatattatca taataacata aaaaagtaca ctttttgggg
    45181 gcgtagttat tgaaaaaatc taagagaaag attgccacgt tgcttatgtt aattgtgcaa
    45241 tttacaggaa ttgcaatgag tgtaatcaca ataaatccgc aagtgataca tgctgatggg
    45301 atagctactt atgatgcaca atttaactgt actactgaag gtagtgggtc aggaacagat
    45361 agcgatggaa acgatactgg aagtggcgct gtaacaggtg atgtagccaa aaatattgaa
    45421 gatatttaca aatacatgaa tggagaatat ggcttatcag gtgctagtat tgcaggtatt
    45481 ttaggtaact ggaaacaaga atcaggtatt gatcctcgag cagtagaagg gtattacgga
    45541 gatggacaga gagaagttga cttcatcaaa caatttactg atggtctgat gggtattggc
    45601 tatggtcaat ggacagctgg gcgacataca gcattagttg attggtctaa gaaaaataat
    45661 ggcggttctt ggtggactac agaagcccaa ttggacttta tgttcaaagg tgatggggga
    45721 ttcgtaggaa tattaaaaga ttatgcttta aatgcttctg atgatgtcgt agaaaatgca
    45781 gtaacttttc ataaaaactg ggaaatttca gctgattccg aatcagctgt aatagctgta
    45841 cgtggtgaaa atgcaaaaga aatctggaag tacatgaaaa gcaagggtat ggacggtgca
    45901 aaagatgaaa gtaagatcaa taaaatatcc ggaggttcaa gtaccggaga tggatcgaat
    45961 aattcatcaa gttcagcatc aggaacagta gaagatgcct gtgcaactac ggatgacgct
    46021 aattctggtt ctggatcaat tgggaaagaa ggaaaaatta acggtaaaaa aggtcaagta
    46081 atagcgaata tgacttatga agaagctttg aaaaaatatg ggaaagcgat cacgctacca
    46141 aaattcaaag aaccagattg gtcaacttca ccttttaacg gaatatatca aggtcagtgt
    46201 acagagttga cgtgggctta tatgagccaa ttatacgatg ggaatcaacc gactactgga
    46261 aatggtggct atgtatggga aagctacaaa tcggcaggag caaaaataac gaacaaacca
    46321 atcgtaggtt atgggtttag tgcttcggat ggatggttat gggctgttgg agatgcaggg
    46381 catactggtg tagttatagc ggtgtttgaa gatggatcat ttctatgtgc taactttaat
    46441 gttccaccaa cccaagctcc aacaagggga gtttcggtaa cgttgattga tggagtggac
    46501 ggatcagata atgtgcattt ctttagcggt gtaggaaaag ctaaatttga aatcgaaaaa
    46561 taaattggaa tgaaggacga tatagatgaa tagtaaagtg aaagatacaa ttatcatttc
    46621 tttgctttct ggtatgttat tagcactgct tgttggaatc ctattcttca ataagcagaa
    46681 tcaggacata gaagctgaaa aacacagtgt gcatattgaa gataagctaa cattctttaa
    46741 agaggttaaa ccaaatgagg tggatggatt acggaaagat ttagaaaatg atattcaaga
    46801 aatgttgaat ggatcagttc aaaataagtt tgcagatcaa tcaggtgaag aatttttgag
    46861 aaaactattt attgtaacag gtaaaccacc aattactgat aagagtagtg agaaagaaaa
    46921 aatcgagtac tataagcctt ttacttttaa gctaacaaac tttggaatta agacatctag
    46981 tagtgggttg tatgaagcat tgaccgattt tgaagttcaa tacaatggaa aaaaagtgta
    47041 tgataccaca ttaaccatca cactaaataa tgataagaaa gtgactgggg gtgcttttta
    47101 tgcaaaatca tgaaatcact actgctaaaa aggcgatcgg aatactttcc ataattgtga
    47161 tcctttgttg tgtggtacta tttcaaaaga aaaatgctta tgataataat gtcaaagaat
    47221 tggaagacct taaaagtaaa caaatcgaag tagtcaagaa taaccagaaa gtgaaagcta
    47281 tgcaggaagc tcaatacaaa gaattgggaa atgctgaaat taaggaacaa agtaggaaat
    47341 tctttaattt attttacaac tggaattcat gggaaaaata tacgaagaat atgaaggaaa
    47401 tacaaaaaga atttcctcag atagtaaagt ctagtcctgt tgatatttct ggcacgatgg
    47461 taggcactgg taatagtcca atatctagct atactgctga ttactataca acaaatcaaa
    47521 aaggtaaaat ggttgaattg attacacaga caagaaatac tccaacaaca gcaacaacaa
    47581 caatttggcg tggagtaaca agcataggag aaaatcaatt gttttatttg gaggatttag
    47641 atagctatgt aagagcagag taaaataaaa aaagagctaa cggtaccaac gttagctctt
    47701 tgtgctgacg atgataacaa aacctaccga aaaaggattg tttcatcaca aacacaaaca
    47761 gaaaagaatt gataaaaaac ccgaacctca gaatttttat taatcaattc atttagatta
    47821 taataaattg agctgaacat tacaatacgt atatgttgta aaacgtaaaa aaagtcaaaa
    47881 gtaaatactt tcttaaaaag tcaaataaaa ctattaaaga caatatatat ggtttatttg
    47941 acataagaaa atggtctaga tgataattgt aatatagaat tgtagactta aataaagcat
    48001 aaaatacctt ttatgataag gtatagctct taattttaag cagttttaga tataagattg
    48061 aaagtaaagt gggggagaat aataatggca gatcataaat tagaaaagtt attagaagaa
    48121 acgtggaatc caaaagaatt tagtgaattt tttatggaga attttgaaac tgacttagca
    48181 gtgattgtta aagatgctct tagagagcaa gggtatcctg aaactgcaaa ctatataaac
    48241 attaatttta ctttgtatac tgaaaataaa ggaacttggg atttttgggc tactttagca
    48301 aataaggagt taagtgataa atcagacaca ggaattcgta acttttttga atcaaacaga
    48361 gatgattata tgtatgctaa caatcaaaat aaattgaact ttagagtaga gtttgatgaa
    48421 acacctgaag aatttataga aagacaaccg cctaaagaaa atgtagcaaa ggtattggaa
    48481 gatcgttgga attcagatga aatagtttca acaattagcg aactaggcgg acaatatgaa
    48541 ccgctagtag aagcggttag agaagagcta agactgaata agtttcctga tgttcaaaat
    48601 attgatgttt ctcaaattga aataaacgtc aagattacga ataaacttga ttatggtagt
    48661 tgggcagata tagcattaga aaaatacatc tactcaacgt taaaagagtt tatcgaaaat
    48721 agaatggata tcatgtatct acagcatcca cagtatttaa actttggtgt tgaaatagct
    48781 acacctcttg aagaatggaa aatggagcaa gggcttgact agcctttgct ccattttttt
    48841 attttacaaa tgaatacagt tcgtcgtttt taccaagaat gattgtttgc ccaactttga
    48901 gattgtcagg tgatccttca gcggtttgta aggagaacgt tccattgaac ttatcggata
    48961 ccgttatagg tagctttaat tctgatcctt cctcatcttt gagaattgct gtttttcgtt
    49021 catcaaaata aacagtcttt attaaataat ttttcgtagt gatctcagaa gatttgtctt
    49081 tttttgtagt agtaccagtt tctttagaat tagaggtatt ttctacgact attccatctt
    49141 tggcatttga gcttgtgttt atttgattga atattttcag cgacaagata ccgctaagaa
    49201 tagtcaatat agaaataagt gtaattaata ctgataattt cctttttttg ttcatttttc
    49261 ttaacttcct tttttgtttt gattagttag atattcctta tctaacaagc atttttaggc
    49321 tattaaatga agataaaccc caaaaaaata ttgcaattat gacagtgcaa tggtactatt
    49381 attatacaat aaattttgcg aaaggggtag gtctaaatcg caaacaaaaa gaaattgaac
    49441 ctagacaaat acaacttgta taccgcaagg gaagcaagtt tgattttggg taaaggtaga
    49501 aattatgtta caaacataat caactattat ccaaatcgtt tgcctaaagg ttcgttcaag
    49561 aaagtgggtg acaaaaccta tattataacg gaagaaggaa tagaagcatt gcgatcacaa
    49621 acagaaaata aaaacaaaaa gaaggaatga atatgaagaa aaattcgctt ggtatggttt
    49681 tatttgcatc agctgtactt gcggggttat cagtaccagt aacctcacat gctgatgaat
    49741 ggactgcaaa cacaccggat caaatccaaa ttacaacagg acaatcaagt tatgcgttca
    49801 aaaaaggaga tactatttgg tcaactgtag agaagcttaa aagcttaggt tacaagacta
    49861 ctgttgctga gtttgccgaa ttgaacaatg ttgatttggc aaaaggagaa caacgaacta
    49921 tcccgattgg acgaactttc aacatcagta aagatacatt aacagttaag gaagcagatg
    49981 gcgaagtagt tagtcaaact gttcaaaaag ataaacctga tcctgttgaa aatacggagc
    50041 aagagaacaa aaaatccgag actacaaaag aatcggaacc aacagcaaac acttctgata
    50101 agacagaaac aagtgcttca agtgttgatg gagcaagttc atctaataca aataattcta
    50161 caagtgagaa agaagcatca cagggaacaa gtgaaagtag cactacggaa gctgatactg
    50221 gaacatcaac aaataactca caatcaacat caaatgatgc aaatgaatca accagtacat
    50281 cttctagtga tcaatcacaa acaggttcga gtgatgaaac tgacagttct acttcaccaa
    50341 gtaaacccga acaaccaact aatgttgtgc taggcgttcc atttattagt caaggtaaca
    50401 caatgctttg cgaaggaaca tctttgctag aagcgttaca ttataaaggt gttgcaacaa
    50461 atcaagattt aatgactttt gttaaatcaa tgccactatc tcctgataat aatccaaata
    50521 atggtttttc tggtgaatgg agacacaatg tggatggaac ttatcaaggt atgaatccgg
    50581 ctcctgtagt ttcatggggt gttgctaatg gcggaaatgt tgtagatatt tctggttcat
    50641 cggtacaagg attaaaagat gagattgtaa atggaaatcc tgtagtagca tgggtaactt
    50701 atgcctttga acctgctcaa cataaatcaa tgttttgggg cgatgctatt tggaatcgac
    50761 atgtagtagc cgttgatgga tttaaagacg gtttttacca tgttgtcgat cctgtgtttg
    50821 gggcaagttg gattaatgca ggatcatttg aaacagcata taacgtatct caattagcgg
    50881 tttcggtacg ttaataaaag agatcgttta tatactaagt agttaagtat agtctttatt
    50941 tgtccttaat taactactta gaaaacttgt tgctcatggt gggtagaact aaaaggggtg
    51001 atgctatgaa taatagagcg ttgaaacatc ttgctttcaa cgaaaaaagt gattaatagg
    51061 tgtggtgatt ttaacttagg aatgggcgcg aaggtcatta ccacaccgac atatcgtggc
    51121 tcattttctt cgcctaactt gcataaagaa ggagtaacga gagatgaagc atgaaaaaac
    51181 gataatttta aaatcaaaaa taatttattg ttttgcgact ttagtaatgg tgttatctac
    51241 gcttataatg cctttttcag caataagagc tgaagcagat gtcacaaaac cgacaagtgc
    51301 aaaatttaca gaaactggcg taaaaacaga cggttatatt agggttaata tgccgaatca
    51361 tccaaatgaa tggatgattt caagtcaatt taaagattct catggaaata ttggatattg
    51421 tatggattca gaattgccat ccccaacagg aagtggagcc ggaagcttga agtacaaggg
    51481 agatggcagt gatgagttct atcgtatgtt taaaggtggt tttccatcaa aaacagcaaa
    51541 ggaactgggt gcaggaaatg atacagaagc atggtatgca acacaattag tttcatgggt
    51601 tttagccgga aactttaaag tttcacagat tgtatggtca catccaaacc ataccgccgc
    51661 agaaacagct cgtgtaaaaa aagcatttga aaaaatttat gactatgcta agaatggaaa
    51721 agatacgccc aacactgagt tttctatcac agcttctaag acagctgacg aaggaaaata
    51781 tcacactttc acatataaaa cagcatcaaa taagactggt aatgcgaagc tcacttttac
    51841 atcagcaaaa ccagctggta tgaagattta tgatgcagat ggtaaagaaa ttactaacaa
    51901 cactgtgaaa ttaaattcaa gttttactat taaagtacct gtgactacac caagtggtac
    51961 tttgtcattt aaaggtactg ctaatgttag cacaaccaat ccttttactt ttgatggacg
    52021 aggtgtgtat caagatgccg tagttatgat cactacttca gaaacaaagg actctaaatc
    52081 tttgagtgct aaatggacaa gagctgttgg tcaggtaaca gttaagaaag ttgatcaaga
    52141 tggaaatgct ttaaaaggag cggagtttac tctaactgac aataacaatg ctaaatctgt
    52201 taagacaacc ggagatgatg ggttagctac gtttgatttg caacaaggct taacatacag
    52261 cttagaagaa acaaaagttc ctgaaggtta tcaaggttca tttaaaaagg atggtattac
    52321 tgttaatacc gatggacaag aatttagtta cactgctacg aacacaatta aaaaaggtaa
    52381 agtaaaagtt aaaaaggttg accaagatgg aaaaccatta gctaatgctg aatttacctt
    52441 gacggatgat tcatcccaaa cacaagcaga aaaaacagat gaaaacggac ttgcaagctt
    52501 cgatattgta gcaaacaaga cctacagcct tgaagagacc ggagtaccaa ctggttatac
    52561 aggcgtattc aagaaagaag gaattaccgt taaagatgat ggacaaactt ttgaatatac
    52621 agctacaaac actttgaaaa aaggtttagt aaaagttcat aaagtcgatc aagatggaaa
    52681 acctttggca aatgcagagt tcactttaac cgatgaaaaa ggtgaaacac aagtagaaaa
    52741 aacagatgaa aatggacttg caagcttcaa tattgtagca aacaagacgt atagcctaga
    52801 agaaaccgga gtaccagtag gttacacagg tgcatttaag caagagggta tcaccgttaa
    52861 agacgatggg caaacttttg aatatacagc tacaaataat ttgaaaaaag gtttagtaaa
    52921 agttcataaa gtcgatcaag atggaaaacc tttagcagat gcagaattca ccttaacgga
    52981 tgaaaaaggt gtaaaagaag ttaaaaagac ggatgcaact ggtctggcta cgttcaacat
    53041 tattgcgaac aaaacttata acttagaaga aacaaaagta ccaacaggtt acacaggcgc
    53101 attcaaacaa gaaggaatta ccgtcaaaga tgatggacaa gtctttgaat atactgctaa
    53161 aaacactttg aaaaaaggtg tgatcaaagt tcataaagtg gatgatcaag ggaaagcatt
    53221 agcaaacgca gaattcactt tgacagacga caaaggtgta aaagttgtac aaaaaacgga
    53281 cagcaatggc ttggcaacat ttaatattgt tgccaacaaa acgtacaaaa tcgaagaaac
    53341 acaaaaccct aatggttata cagggaaatg gtctaaagaa ggcatcaccg ttgctgacga
    53401 tggacaaacc tttgaatata cagtaattaa tcaccttgta cctgaaacag taagaacagg
    53461 cggaatcggt acatcagcct tccttcttgt atttctaatt gcaggattga gtatggtgct
    53521 actgtattat cgagaacagc acaaagcaaa ataaaaaagt gttactggaa aagaagtaaa
    53581 tatgaaaaaa gaaggctgac gtatgaaatc aaaaaaaatt ttttcaaatt taatgctatt
    53641 tggtactttg ctaggagtgg gattgggcgc aagctcaatc tcttctagcc ttggactagg
    53701 ggggcaagta gcatatgcac aacaaaacta taattatcaa ggaactggaa cgattcatat
    53761 ccataaagta acaaatacta atggggatgg gaaccctgtc tcagatattg ataacaaagg
    53821 gaaagaaata gctttaccaa atggtgtaaa acctcttgaa ggcgttgagt tctcttatgt
    53881 gaaacttact aaagatgaag ctaaatcctt gggatggacg gatagtgata ctacaaaagg
    53941 tcaacatatt gatgatgcta aagcacgatt attactaaac aaaaaataca gtgaagtaag
    54001 tagaatgaag actgattcac aagggaatat agacatacct atacaagtaa atacagacga
    54061 tttaacagat aacttgtatt tgattgttga aacaggaaca gtcaaaggtg tagttgaaga
    54121 agcgtatcct atgattgtta acgtacctga actaaacgga tcagatgatc aatactttaa
    54181 ttatgatgta catgtctatc ctaaaaacta tttccaatta aactcagcag agcttgataa
    54241 aaaagacgaa gatggaaagg ctcttgccgg aactgttttt gaattgcgaa aagatgatgg
    54301 atctgatcag gttgttggaa cttataaaac agacagcaca ggtaaattaa ctgtagatgg
    54361 tttggaatta ggtgactatt atttcctaga aaccgatttg ggaacagatg ctaataaaac
    54421 aacctattta ctagatggta aaaaattcaa atttagcgtt aaacgtgggg agactgctaa
    54481 agtagttctt gatgttacca actacaaacg acctgtaatt actaaggtaa ttgataaaga
    54541 aaccgttgat actggcgaag atgttcaata tacattgaaa ccatcaattc ctggtaatat
    54601 tggtaattac gaaaaatatg ttgtcaaaga tgttctaggt gcagagttaa cttatgattc
    54661 atcagaagtg atcgaaggaa tgactttaga tactgattac agtatcgaac gtgacggaca
    54721 aacgacaaac tatgtcttta ctgaatcagg tatggataag cttcagaaac aatttgatgc
    54781 aggggatcgc ttctttacaa ttttgatgaa cgctcatact aatagtaaag ctaaaatgga
    54841 tacaccactt aagaatgatg tttcaacgat ctacaacaat ggatatgaac ccgaagacga
    54901 aacaccagtt gatcacgctt atacaatcat tggtgatcac caattcatta aaacagatgg
    54961 agatacaagc aaagcattga gtggagcaaa atttgtagtg aagaacaaaa ttgatccgaa
    55021 taaagttact tacctaaaac aagatccaac aacgaaagct gttacttgga ttgcagataa
    55081 atctaaagct actgaattcg tttccggatc agatggtaag ttccaaattg aaggcttgca
    55141 atatacctat gatgtagatt ttgataaaca aggtaatcca acaatcacag ataaaaaaat
    55201 caatgattat gctcttgaag aagttgttgc tccttcagga tatacaccaa ctagaaatga
    55261 tattccattt gtggtatcga atgatgatgc ttctagcgaa gtaacagaca tcaagaacct
    55321 taaaacacct gaaacagttc gtacaggtgg aattggaaca gtagtatttc tagtggttgc
    55381 aggtgtggca ggaacagggc tatatgttgt ctacaaacga gaacaacaca aagcttaatg
    55441 aaataaaatt ccctagagtg tttttggctc tagggtttct ttttaaaaag tgtgtgaaaa
    55501 gtaggtatga gcatgaaaaa gaagaatatc aagttgatca tcttaaaaat tgggatgttg
    55561 ctatgtttag gagtaggtct atatcctgta attactcagg cttataccta ctaccaaact
    55621 caacaaacac taaactccta taaggaaaaa tatgatgaag cttctgaaaa ggagaatgaa
    55681 gaagtcttca agagatattc agaagttaat aggaaacgaa aagacacaga acaaacctca
    55741 gtcacgattc ctgaagataa taacaatatt ccgtcaaatg gaaatcttca gaaggataaa
    55801 ttaggtgaat tagtgggtga aattcttata ccaaagatta atgtggattt gccaatttat
    55861 gatggtgtaa acgattttca actatcagca ggagcaggaa tattaaccgg aactgattat
    55921 ccaactggtg ggattggaaa ccattctgtt atatcagctc attcaggcat tcctaataaa
    55981 aaatatttta cagatttaga gttgctcaaa cttggtgata aattttttat tgatatttca
    56041 gggaaaaagc ttgcttatca agtagatcgg ataaaaacaa tcctaccaac cgaatttgag
    56101 gatttgcttc ctgtggcagg aaaagattat gtaacactta tgacatgtac acctgttgga
    56161 gataattctc ataggttact cgttagaggg gttagcatac cttaccaaaa aagtattgtt
    56221 gagaaagaaa agaagaaaga agatttaaag gtaaaggcgc agatgaactg gtatcctatc
    56281 gtagttgtag gggttttatt aataatagct gtgatagtca ttattaaaaa aatagtagca
    56341 aagagacgag gaatgaaaaa tgaagaataa aatactactt tttttgactc ttatttgcac
    56401 tttggtttta acaatttatc ctgcaaatca gctctatcat caattcaaaa caaaagagaa
    56461 tgtggcggaa atccaagaga aaattgagaa aaaacaaact ccttcaaaag aggaagtggc
    56521 aaaaaaagtc gaacaaataa aatcgaacag cggtaaccaa ggattagaca atactcagaa
    56581 aacagacggc gaatcatttg atattggtga agctgaagga aaggtcaatc cttacacagg
    56641 agatgttttt tcaaaaaatc aaacgaaaga ttttgaacca tctacctatt caggggcggt
    56701 tggttatgtc tatattccaa aaataaatgt gctagaactt ttgtttctag gcgcttcaca
    56761 ggagcattta tatagaggtg tggcacagat gagtgctact agtctacctt tatcaggtaa
    56821 aggtcatcaa acagtaatag caggtcatcg tggcggttat acgtcaccac aatttcttta
    56881 tgttgatcaa ttagtagccg gagaccacat ttatatagat tatcttggtg aaaaagcagt
    56941 ttatacggtt ttccgaacag acgttattag aaattacggt cagaattcaa cactgactga
    57001 tattcctgat ttagatatgt taacacttta tacttgtcat ccatatcctc agaactacga
    57061 tcgtttatta gttagaagtc taagagatga aaaagcaaaa tacatcacgc cacaagtaac
    57121 agttggcaat accgcatacg ctgatgccat tgatagtgaa tccgtttcag ataagccaga
    57181 aactgttaca tcttctaatg atttatttga ggatgttgat cgtgccaaca aggaattaga
    57241 tggaaataat gatcttaata ttccggaaca aggtagcgta gagatgcaag acagaacgtt
    57301 tgctgaaaag gcaagttcaa tatttacagg aattaccaat aaacatcaga aaatgctttt
    57361 agtcatttgg actgtattag gagcattagc aagtctaaag gttcttattc ttttaatcaa
    57421 agagtttaga aaagcataat gaagattata aaaattgata gagtacagta aaaagggatt
    57481 gatactatta ttgatctctt ttttattttg aatagagcta gattcacttt taaataaaat
    57541 caaaactgat cttaattcca aagaaaaagt caagaaaaaa atacaacaaa tttttttatc
    57601 agaatattta tcagaatatt attagaaaag ataaactcaa aagcttaatt taatagggtt
    57661 attggttgta tttagaaata atttatggaa aagctataaa gcaatagata agatgtagaa
    57721 aatcttattt gtgaatgaaa aacaagtcat cgtaaaatat taataggagg tgtagtaatg
    57781 gtggaaatat caaaaacagc tttagactca ttagctaaac tatttagtag caggtttgat
    57841 ggtgcagaat ttgttgaata tctaagccaa aacgaaagtg gaaaaactct gatcgaaaca
    57901 ctgaaaaaag actatttgaa tgaaaatgac tttccgacat ggacgaatat tgaagatgct
    57961 acatgggatg tagtatgtac gatatattct ccttgggtaa cgattgctga ttttgtttta
    58021 gataaaattg gaggggatac ataccctgat gccaaatctc ttgctacaag tgactttaaa
    58081 acgttctatg gttatctaat aggtctaata ggcaatggaa tagatttgaa agttacgcca
    58141 aaacaaacac ctgaagaaat tgaaaaagaa aaaggagagg ttcaaatggc ttatgcaaat
    58201 gacagagaaa aagtaaaatt attggaaggt aaattatctg aagaagaact tggaaaaatg
    58261 gtgcaagaaa tcaatgaaga cagcaactat tttcctgaat tgaaggtata tcaaaatgac
    58321 gaagatttct ttaatgaaat gtttagtaat agtccatggg aagcagtgag taaaacaaat
    58381 ttaggagaat ggaactttca agatgatcta gttgcattta gcaatgatgg gtatttacga
    58441 tcatattcag aaagtgagta tagagctgaa ttaaaaacgt atgaaacgga tattctgatg
    58501 agctatttaa atctattaga gagtggtcag ggagagttaa gagataaagt tgaagaacta
    58561 ttaaaagaag agctataggg attatttcaa cataaacaca agcagaaaac taccaaacaa
    58621 aacgtaccat gcaaaaagcc ggttaaaccg gctttttgct ctattatgag aggagatcaa
    58681 accatgagtg caacaaccga tatggcttta gaagcagtaa taaaagataa tacaggaaat
    58741 gtcgaaaatg tagaagactt tagcgatatt gcaatcaatc tttcagcatg gatttcagct
    58801 gtaggagaag aaaatatcga atttgagatc aagaatatgg atgacttaaa agcaaaattt
    58861 ccttttattg catcgaaact aagtcaagtt gccgaggata aatcgtggaa tgaattagtt
    58921 agtttttccg aaaaaattta tgatattacg caagaagatg agtgtgtttc atgggaaatg
    58981 aataatcaat acaagaaaat tgacgctttc gtcaaatcac gtatagaagg aacagctttt
    59041 gagtttgaag gtatagatac cgcagataat tggttaaata aagaatcctt tattaaaagt
    59101 atagcggatg atcttgaaaa acaatggtct aaggaagact atgcagagta cctaaaaaca
    59161 gaaagagata cagaggtgaa agaaaaactc actgaggtat gtttggatga acatattgat
    59221 cccaatatcg taaaacaaga agactatgaa gtggttattg ataaagttcc tactgatttt
    59281 gaggaagttg taaagtatat agttgaagaa gcattatcgc aatactcttc agatgaggaa
    59341 gtggacgaag aaactgttcg taccagagtt tggcaactgg tttttgatga caaagattat
    59401 aaatatttga gtgatcaaaa ctcggttaat tggagtgtac gattattaat tgatcaaaat
    59461 gatattgaat aaaatagagc tgaaaagctc tatttttttt gataaaaaaa ctagctattt
    59521 tattaaaaat aatttggttc aaaatttatt tttttaactt gataattttt tgccatcctt
    59581 ttttaaattg gctatatatc aatgtttgta gtgggaataa ataaaaatac atttgacaaa
    59641 atttacaata tagtttatta tatatttatc ttattatgat aacacaataa aaggaatggt
    59701 ggtatggaaa agaagaagtt tagccgatcg ttgttaggaa ttttggtttt agttgcggtt
    59761 ggtcttagtg gcaagggtta ctttcagaat aacagtactc aggaacatga ttttcagatc
    59821 aaaagtagtg ttcaggtagg taataaagca gacagtgaat caaaagaatt tttagggata
    59881 cgttatgatc caaacaaata tccaaataat atcgtaaaca ttaatgatgg gaaatataca
    59941 ctgacaaaag aagaccatga agcattatca gaaaaaggca gtcaaacctt ttgggtaaat
    60001 tatgcagatt tagatcaact tggaagagca ggagatgttg aagcgttgat cacctatgat
    60061 gctgtaaatt ctcactcatc taaaaatgtg gaacgtccat ctttcaaaag ttctgtccat
    60121 attgcaggag aatacaagga tggagtattt gatcaagaga gagatacttg ggtcggcaaa
    60181 gattcaaaca atgaaatcac tcagctagaa ggctataaag gttatctcta taacaaaagt
    60241 cattcattag catggtcgct aggaggagat atggaggtac acaatttaac acttggaacg
    60301 agagcgcaaa atgttgggaa aaatgatcag aatggaggga tggcttactc agaaacgatt
    60361 gtacgtgatg caatctataa aaataagaat gaaaaagtat tgtataaagt tgatccaatt
    60421 tataaaggga atgaattagt tcctcgtggt tctcatgtcg aagctttctc agttaacgat
    60481 aatggaaaaa cggtaaacct taatgtttat gtatttaaca atcaaaaagg aatcaacatc
    60541 aactatcaaa atggtacttg ggtaagagat tagaaattga gaaggtgaag aattggaaac
    60601 aataagcatc aatggattag ataaatcagt tgcaaatcga ataaaaaaag gaaatggcta
    60661 ctatcttctg aagaagggta aatattcagt tgctagagag ttagaaacaa tgagtatcgt
    60721 gtatgtagct aagaatcatt ttgacgtaga acaggctatt tttgatccag attctgaaat
    60781 agggaaatgt gttgaattat cagagaaaac tgttagtaca aaaggggcga tgatcattga
    60841 gagagaaatg ttagacgaaa tcagagtaat cattcctaaa gatacgcaga tgtgtgagga
    60901 cagcataagt gacgatgaac caaaatcaga aagaaaataa ggagatattc agatgatcaa
    60961 aaaatccatt gaattaaagg aatataagcg aagcgatgga gaaaaatatt atcctgtagc
    61021 cagtttttct aaatcagtat atctggttgg acgtgcattg atagttggtg caattggcat
    61081 atatattttg cattgggtaa caaaggttgt acaactgctt gtagatacct tagtaagtat
    61141 tcttgtctcg ttgaatgatg ttaacggaac agatgattta ggattgaaag agatgtttaa
    61201 agagttactc aatgcgtttt ttccaaatta tttaagttat tcatataatg cacaaaactt
    61261 ttttgcaaag ctacacttgg tagacatctc aattttagta ttagaagcag gagcggtatt
    61321 ctttgttgga tatttggtta cattgatgtt ccggcatcac tatggagaac aaagaccatt
    61381 ttttgatgat atggaaagta gaaggttgaa aagagaagct ctagaagcta tggatgtgaa
    61441 gtatgatcca aacaagatta taggagatga aacgaacaac aaaaaaagaa aacgacacaa
    61501 aacgcaatta gaatccgatg tgctatcaac gcttaaaaat atcaaaattt ctgttcatac
    61561 aagacgtgat ctaagtgtca atgaagatat tcgagaatat atcgtaaaaa tcccgcaacc
    61621 aaaagggaag aaagttagag aaacagtttt acgacaaatt caagatttag ggtcgatcct
    61681 gacaagagca acaagcggac gagccaaatt tggtgaaaaa gaagatgaag tttcaggcga
    61741 ttatttcatt ttccgagcat cagtaaatat tgaaagagaa cgtaaggaaa gagtaagtac
    61801 taaaaacaaa gaaacggaaa aagcaacatc ttcaatcgca gtttcaaatt cacaattttc
    61861 ttttccaatc aatctctttg ccgataattc caaaaacatc caaaaccaaa ccgaaaaagc
    61921 tagaaaatat gccgaaactc aaaagcaatc tttagaactt tatctatctt ctgctgacgt
    61981 acctgcaagt ctaacagata tgcacgttgg gaatacatct attgaatatt tgtttacttt
    62041 atctcgtacc agaaaaattc aactaagctc aatgaaagaa gaaattgaaa cttacttgca
    62101 tatatcaggt gtaatcgtgc ggatcaacgc aggacgtatt caaattactt taccattagg
    62161 agaaaatgat cgtattccaa ttgatgtacc atcaatgatc aatagcgtgt tttagaagac
    62221 atcacaaata gaaacagaaa atacaaacta ccagttcaca aacagaaaag taccgagaaa
    62281 agcgaggaat agaaatggct atgaaattat tagagaaagt caaaaaaaga gcagaaaaag
    62341 ctgaatccat tttgctagat aaagaaccta ataaaaagct taatggaaaa ttcagtgtca
    62401 atatgttgaa cacaaaagct aaagacccga cagatgccat tcttggaatt aagcctgatg
    62461 gaacaattgc tcatttttgc attagcgaaa tgccacactt gttggttgca ggaacgacag
    62521 gatcagggaa atcggtgtta ctaaatgaaa ttcttgttac agcaatgtgt cactcaacgc
    62581 ctgatgaatt aaaaatagga attgtagacc caaaaagggt tgaatttgga agatacaaaa
    62641 aattgccgtt catgttggct gatccaatta cagatatgga tgaagcttat gatttttttg
    62701 aatatcttgt gatcttgatg catgagcgtt acaaactgat ggaaaaagca ggggtacaaa
    62761 aaatcacgct atataacgaa tatgccgaaa aaaatggatt agatagattt ccctatgtga
    62821 tcttattagt tgatgaatat tcacagttgg ttggaacaca taaagaagta gaaggtttga
    62881 ttgttcaatt aggacaaatg gcaagggcag caggtattca tgttatcctc gctacacaat
    62941 ctcctcgatc aacagttgtc actggtatta tcaaagccaa ttttccgtca cgtgtttgcc
    63001 ttatggtagc aagtgattta gaaagtagga tcgtattaga tgaaggcggt ggagaaagcc
    63061 taagtccaaa gggagatatg attattaagc acgttaatgg aagtatggtt agagcgcagg
    63121 gagcttacat cagtaacaaa gaaattgaaa caatcttcaa tcaccttaga aatactatgc
    63181 cagaaccaga atatgttgat taccgagcaa ttgtagctga atctcgtggt gagggtggag
    63241 aagacgagga ttttggtgga attggtaaag ctcctgtaag aaaatctgct aaaagaaatt
    63301 taagcacacc tttagcaaat ccatcatcta aagagccatc aattgaaaag aagagtgcgt
    63361 ttgctattaa gcttgagaag aacaaagaag aaaaagtcga gcagggagct aaaacactag
    63421 aaaaactgca agcagaaaaa ctagaaaaag ttttaagggc tttaggaaat gctgatcctg
    63481 aaccgcaaac ctcaaacaac acgaataata aacagccgat tacatctaaa actaaaccga
    63541 aaactactga tccgaaagtt tcagtaaacg tgaccatcac aaccgataat tctgagaaga
    63601 aacaagtaaa cggaactact tcacctatca tgcaaaaaat gttaaaagaa aaaaaacagg
    63661 tgcataaatg atcattgtca gttctttttt gaggtggctt acgccatata aatatacaga
    63721 tgaagtagtt gtgaaacgag ctaagaaaaa agataaaaaa gcagtgttaa ctcctaaaca
    63781 gatgcttgat catggaattt tgggtgtgaa ggttttagaa atgaataaac cgtttgaatc
    63841 aaatagtgca agagaaaagt tgcttggtgc tgaagcagat gtggcatatt tttatcatga
    63901 caaaagcaag catcaaatag ctattaaatt caatccaaaa tcggcatggc ggtatcaagc
    63961 aagagacgac ttaaaacgta ggaaacttag accaatgctc tatccagaag gaaaagaagc
    64021 atttgataga acccacatcg ttcccatcgg gtttcatggt acagaatcag ataatcgcct
    64081 attagtaggt tggaacagca atcaaaatag aattcagatc aataaatttg agaagaaagt
    64141 aagaaaattc aacgatctaa aaacaatcct atggtttgca gatatttgta aacagccgga
    64201 cggaacagca aagtgggaag cggtgatatt tgacgaaaat ggtaaaaaag taatgtctga
    64261 aacatggcat gataaagcta aatttgtttg gcagtagcag tagaggtgaa aaagattgct
    64321 agaacttttt gaagcaaata gaacaggctt taatcaaaaa ttagaagtgg gagaaactat
    64381 agaatataaa gataaaaact atattattat cggaatctat aacacgagga ttaacagaat
    64441 aggtgatcca cgtataacca gtgacttggt ttgtcaatct gttaactatt cacctgatct
    64501 gacaagcagg tataagaaat acgtgttatt agaatataga cacaagatta ctgatgaaaa
    64561 tagtgtaaac aacacacgaa acatatttaa gatcggaaca gtgatccctt atagtaacaa
    64621 cgaagaaaaa atattttatc agatttacgg aatagaaaag tttgaatatg aacatgtcga
    64681 tctgctagtg acgtaccaaa tgcgtttaat tgaaccttgg tcacaggcag aaattgataa
    64741 agcagtaaaa ttgaaccgat tatcaaaatt taacgtatta ggaaatgcct tttaaaaatc
    64801 gcaatacaca aacagaaaaa taccaaaaaa ttagcaatga acgtaggtaa gaacatgaca
    64861 ataaataata ataaccctaa aaaatataat gctcttgtcc aatgctatat cgaaaacaaa
    64921 attacaatgc aagaagtcgc tgatgaatta ggcaaatcaa agagcctagt atcacacgac
    64981 tttaagcaca atgtttttcc gaacccgatt gagctgagga aaaaatttca aaagagagtt
    65041 tatcaagaaa taggtaagtg gattgatgaa ggaaatgcaa ttgacccttt aattgaaaaa
    65101 tatccttttt taaaaagcaa aaataaaatt caaaggttaa ttcgtcaagg cgatattcaa
    65161 gctaaagaac ctgttttgac aaccaatgat ttggctaaaa taaatcttca taaacagatt
    65221 attgaagact ttgaaaaaaa tctttcaaca actgaaattt taaaaaaata caatattccg
    65281 agaggaaagc taacatcgac tctttttaga gaatatggag aatcggcagt tactaaagca
    65341 aaggaagtag cgaatgagag aaaaaaacaa aaatagtagt cgatacctag tagcgactgt
    65401 agtttttgtt tgtgtattga ttttcctgtt tgattttttg cagattggaa aaagcataat
    65461 tggaaataca ttgagtgcaa aggaaatggt tgctttaggt ggtttgtatg aaggacattt
    65521 gttcccgaat atattcattt ctatcgtttc tcatattaac ttgtaccatt taatttctaa
    65581 tttattgttc ttagtagttc ttgaagaagc actgaatgat caatatgagt ggttaacact
    65641 attgattgtt ttaatcatat caggacttct aggaagctta gttccttttc tgttacaaag
    65701 caacatcgta agtatggggc ttagtggagg tatttttgga tggattgctt tatttgcgat
    65761 tgcatacatc cgctttgata gtaaggaaca tttattacta agtgttttta tattattgat
    65821 aatcggcatt ttactggtat ctacttttga atcaggcgag acaaacgtct tgtcacatgt
    65881 aatcggattt gtctgtggga tgatcttggg atttattcta aagaacgttt cattgatcaa
    65941 gcaaaagaat taaaagggag tgctaaaaat gccaaaaaaa aaagaaaaga aaattccagt
    66001 gtttttgtct gtctcagaaa tgttatcact tcaaatactg ttaagaaaaa agattgaaac
    66061 aatagacgaa gaagttagaa ataaaagggc tatgtacgaa caacgtgaag cgctaagaga
    66121 acgaatccac tattttgatg atatacacac taaaatctat gaagcacgta caaataacga
    66181 agacgaaagc aaattaggat tagctcaaca acgaatattt gaatggctaa atacgaatac
    66241 tgagcaagaa ccgttaagag caattagtaa tctttttgaa tttggaacga agcattggtt
    66301 taacgcagta gaaaaggatg ctgacttaca agaagccttt gacacgctaa gtaaggatag
    66361 caaatccatg cgagatttat tgattactta tctaaatgag catgagtttg aacaaacgaa
    66421 aaccaaaaag aaaaataaag aatagaaagt tgtgatgaat catgctatta accctgttag
    66481 gttatttatg tttaattctt gctttttttg ggacaatcgc tataattatt ggtcaatttc
    66541 aaacaaataa tccgattatg cgtaacatag gtattggaat tgtgattgta acctttattg
    66601 tgtttaatgc cactaagatt tttggaagta acgataaaca atttggtata tcgggagtta
    66661 ataatagtta tgctccagat tctttgggaa gggtagtaat agatggaaca tttgaaaatg
    66721 taacgagtta taaaaatgtt tcgctgacag tgaaggaaga tggcaagaaa gcatcagacg
    66781 acgttctcgc tactattaag ccgtcacaat cacaatttga agtgttttat acagtcaaag
    66841 agaatagccc tgtacacaag ctgacattgg tttttaacgt tgatggagaa gaatactata
    66901 aagatgtaaa aataaataaa acatcaacga aaaagattat cgaatcagcg aaaaaagaag
    66961 tagctacaga agaaagtaca actgaatcaa gttctactgt cgaagcggaa ctaccagata
    67021 aaattgattt tgatcctgaa aaagtcaaat cgtttgaatc tgtttctggt tctatggctg
    67081 atcggtttaa cactgaagtc ttcaaagcta tcaaaactgt taaattggat actgaaaagc
    67141 aaatgattaa tgttacctta ttcaattcag ttgaatctat ggatcaggat aaaaaagtta
    67201 cggttgcaag agaactagga aaaagagtaa ttggtttgta tcgtggtact gctaaaccag
    67261 attcagacgg tgcagatttg ccagttcatg tagtttatga agacggtaaa gtttttggag
    67321 attctacagc aaacgaagca ttaacgatta aattggctaa atagccagaa agttataata
    67381 aacaaatggt gtcacaccaa taatatatag gtgtgacacc ttggagatga tagctgatgg
    67441 tagtaaataa agaaaaagtt agaaagtatg tgactttaaa aatagcttct gttaaatatt
    67501 tagaaaagcg agctaaagaa gaagaaagag caagaggtaa gaaagtaaca gtttcagagt
    67561 tgttagaaga attgatcgag aatgatcaaa caataagacg tgcatttact aataggtcta
    67621 tcagataaca atataattaa taaaaaagaa agagtgattt ggtcttagac taaatcactc
    67681 tttctatata aagtttcttt acacttattc cgaataatgt taaaattctt tatacgatat
    67741 atagttactt gtcagagaaa gagataacca gcaatattgg agggataata agtggaaaac
    67801 aataatgata ttagacattt tagcattggg gaaagagtta caacagtaag tgaattatca
    67861 aaggattata gagataaaga gggaacgatt atttctctta ataagaatcg aagaggcgtt
    67921 tggcaatatg ttgttgattt aggtgatggc gttacagttg agtgtaaaga tagtcaactg
    67981 atcagaaatg atggcagtca ttccattgaa aaagcaattc ttgtataccc aaaagtatca
    68041 agtaagatca tgaatgactg gttgcttgga aaatttggtg agtacaataa aaaagaaatc
    68101 gcagaagtga tcggcaaatc ttatccaaca gtattagggt atctaaaaaa gataactaac
    68161 aaagaagcga aagttgagga tgttttaaca gtaagagaac ttcagtcatt aatcgaatat
    68221 cggaataaac aaataacaaa tcctgagtac cttaaaaaag aagatggtct attgaaacaa
    68281 ttggaacagg taaataaaat ccggaagatg caaaaggtag ctcctttaag cctagataac
    68341 tttaaaaaaa tttatttgaa agagatcgaa aaagactaat gtggagtgtc actttaccgt
    68401 ttcaacctgt atctgcacca agaccaagtg caagaaggaa tgtttctgat gcaactaatg
    68461 acgtagcaga gaaaaggatt tcaacctatt atgataaaaa gtatctcgat tatttgaaaa
    68521 aaataaaaag ctttatcgaa gatcaaggtt tgttagatga tgaattttac tcgatcgtaa
    68581 atgatccgat gggtgcaatt atggaagtgg acttttacta tcagatacca aaaagctata
    68641 aaaaagtcta taacattatg aagacgacag cgccagactt agataattta gtaaaaagtg
    68701 ctatggatgg tattttcaac atctcagcta tacgagatag ccatatcaca ggcttaattg
    68761 cttttaaata taatgtggcg aacgaaggaa aaacagttgt gaggatcaaa cgatattcag
    68821 aatttgagtg ggatacttct gaaggattga acggagatat atgggaagct acatttgatt
    68881 tcaaaccagt agcaacgcca agaccaaagt ctaaatttag aggaaatggg attatcactt
    68941 actatccaaa agagtacaac gactatttgg aaaatatcaa gaatacgctt aaagagaaag
    69001 atttggtaaa tgatcaactg aaaaaggtaa tgaatgctcc tatgggggtt atagctcaga
    69061 tagattattt ttaccaagtg agaaaagata agaaaaagct tgattcactg atgcgtactt
    69121 cacagccgga tattgataat ttagtcaaag gaacattgga cggaattttt aacaaggaaa
    69181 taggcatcaa agatagcagg gttgtagggt taattgcttt taaatacaat acttttgaaa
    69241 agtcgaaaac aaacgtgaga ctacaggaga tgggctgatg aataataatg aaaaaattct
    69301 tcatgtactt gatagctttg aaacaattca agaagaacta aagaaatatc gggatgtttt
    69361 ggaacaaaga tatgattttg tcaatcagca aaagagtaat cacatggatt tcattctcaa
    69421 tatgaatgac ttgaagaaga aattagttga acgaaaagaa caagaaaagt tgatcaaagc
    69481 ttactttgaa ctcggtgaaa aagaagttaa aaaggcaatg gaactgaatg aagatcgcag
    69541 ggttttagat cagctgttag aacaattatt ggtgatgttt caaaaaggac gaatagatga
    69601 ggatttaatt gaagaagggt tgagaaagta tccttcaaac tcaggtatcg gaatagtgct
    69661 gaaagcgatt gatgaagaag aaattgaagc tttcataccg ccagaggatt ttgaatcggc
    69721 aatggaatat ataaaatatt atagccaagg gatcactgct tttagagagt ttgatcctga
    69781 agatgttatt catgacttga acaacctaaa agaatggtgt gaaagttatg aagtcgatga
    69841 ttccggattg gactacttga tcagtattat ggaaatcgaa gaagagatgc cggataagcc
    69901 tgatccaaca gatattttag aattgatcca tgaagctaga aatccaattg cctatatttc
    69961 tagaggatat actgtattgg aatactataa gccttatata tcagcgatga accatttaag
    70021 acgtgtatta agggaaaaac gtgaataccg ctcagtgttg aatgcaacga atagattaga
    70081 aaaagctgtt tcagagctag aggcttatta tcgtgaacat tacctgcaag caggtggtat
    70141 gccaagaaat acgaaagcaa atatcagtag gtatataaaa aaagctgagt aggcggagtt
    70201 agcccgtaaa atggcaaaag gtaacctgaa aggggcattt tgaatgaaaa gggatgtttt
    70261 tgaattgtac gtattagaac gtctagaaga cggcatgatg gcacaagaga taattgatga
    70321 aattgatgat atgatcagca gatttggtca attggagttg aatgatggaa acaaaaatcc
    70381 ggtagtgcta aaacaatttt ggttgaacaa tttttcgtat aaggatttta tcaaagaaaa
    70441 ggcaaataca ttgtactgac taaattcatg aggagcagtg atgagagctt attgctaaga
    70501 gcagttaggc tctttttttg tttgtgtaaa attatttgtt ttacaataca catttataca
    70561 caaaaaatgt tgacggatag tacacaaatg tggtaggata tatttgtaag caagttagat
    70621 taacaagtta aaggaaggaa gagcagttat gaaaaaagaa gaactaatag atatatttca
    70681 aattgttgaa cgagcaaata atatgggaat tatgtttttt gatcgtattt ctttaaagat
    70741 ggatttaagc gttgcccacc aagaatttaa tctacgatta aaagccttgt tgaattctga
    70801 tgatgttaat ttcgctcatg atgttgtagg catacagaac catatagata gagaaaacaa
    70861 acgtatgggt gatggattct taccaagata ttcaagttta taatttgaag aaagattcaa
    70921 gagtatgtgt cattattgat aggtactctt gaattggaaa tgaggaatga atttaagaca
    70981 acaacgatta tgatcttaaa acaatcgttt atgtaattga caatcttacg aataattttc
    71041 atgcaataat gacaataaaa atgaaaaggg gtaaaatcaa atgaaaaaaa ttttagtagg
    71101 aattctattc acaatggggc tagtgctatt atcaccttca gtttcagcag aaagctctat
    71161 ttccatgtat cgtatgtaca atcccaatag cggagagcat ctatacacta gaagcgttgg
    71221 agaaagagac aatctgaaac gttatggatg gcattatgaa ggtgtcgcat ggcaagctcc
    71281 aacaagcggt actcctgttt atcgtctgta taatcggtat aacggtgaac atttttacac
    71341 cattgatgcc ggagaaagag ataagatttc gcacacagga tggacgtacg aaggtgttgc
    71401 gttctattcc tacaacggag caaatagagt tcctgtgacg cgcttgtaca acaaatacgt
    71461 gaattggcac cattacacgt tagatcaaaa tgaaaaaaat atcattagtc gacaagggtg
    71521 gaaaatcgag ggaactggtt ggtatgcaat gccaaacagc gcaccaaatc ctgcacctgc
    71581 tccaagcaat gaaaaagtgt taaatgttcc tgtcatttgg caaggtaata cgatgttgtg
    71641 tgaaggtgct tccctgttag agggattgca ctacaaagga gtagcgacaa atcaaaactt
    71701 aaccagtttt gtaaactata tgccaagagc taatgacaat aatccatatc atggctattc
    71761 tggcgaatgg cgctacaacg taaatggtac gtatcaaggc atgatgcctg atccagtagt
    71821 taaatgggca aaaaatgttg gtggtaatgc cgttaatatc actggttcag gaacgaatgg
    71881 gatcaagaat gaaattcgca atggtaatcc ggttgtaact tggattactt ataactatgc
    71941 gacgccagag ttcaaacaaa tgccttgggg gcgtgccgtt tggaatgggc atgttgtttt
    72001 ggtagacgga tttaagaatg gcgcttacca tgtagtcgat cctgtatttg gagcaaaatg
    72061 gatcaatgca ggcacgtatg aaaaatcgtt caatgtaact ggcatggcgg ttgctgtacg
    72121 ttaattgata gaattaataa ataaatgaaa taagagctta attactgaaa tggtaaatag
    72181 gctcttgttt tttaggaaaa aactgctttt tgtaataaga atatataaca aaaaaatgaa
    72241 tttagtacac aaaagtggta tattaaaacc gtagagatta tgcgaagagg taattttgat
    72301 gaaccaaaga agaagaaaaa gactagaaga aataagcgag cgactatccg agttaaagga
    72361 tgagttagaa gtaattcaag aagaagagga agagtacaaa gaaaatatac ctgaaaatct
    72421 acagggatca gaaagatatg aaaaagcaga agaatccgtt gatcaacttg aagaagctgt
    72481 tgatggttta tccgacatat tagaattgat tgaagatata gctagctaga gatgattaat
    72541 gaagatttca ggagtgagca aaaaatgatt gatatttcac tgatagaaaa gctacttttt
    72601 tcaaataagt acacagccaa agagctggct acaagatggc aaatatccga atcagctatt
    72661 aaagcctatc gtcaaaataa gggaagcgta ggatggcgtg attggaaagg aatcagcatt
    72721 ggaaaagcag aagacataat gaaacgtgaa ggatttcaag ctgacaatga ttctaaaaaa
    72781 gttgaatagt ttaatagtcg ccaagaaaag taccaggacg aggggaaagg tagattacaa
    72841 aggaaaacac ttttaaataa acttcgcaaa agcataaggt tatgagtggc tagggctata
    72901 cgaatgtgat gaaaacaaag ggctttaatg tcaaagaaaa cgcaataggg ggggaataaa
    72961 atttttaaaa aagatattta tgtttggttt aatggaaaaa aatatatgac tactaacaaa
    73021 aggtggtcag agctagtaca aaatacagtt aaaaaagtca tgccagatgg atatcatttc
    73081 aactatatac aatgctcaca aacaactgaa agtatttatt tttcaatatt aaatgagaat
    73141 agactctatt atttcagggt aagttcacac cataggaaaa agagagaaga taatgttacg
    73201 acatttttat cgggaaaata caatggcttc aaagagttaa gtgaagcaat tggtgagtac
    73261 ctaaaaagta atagatttgt cagaatttct gacaaacata tattgatctt gttactttat
    73321 ttgaataata gcttcaaatt gttttggaga gacgacactt tctactatat tgagaacggc
    73381 atggatattt attctggtat caacggcata ttaaaacatt atattaaggc gttacttcga
    73441 tatggggttc tttatcaaga agatttaagt aaccaaatta agattagtaa ttctggaaag
    73501 tcattactgg caaaatataa aaaattgctt tctcctatct acaaaggaat agatatggaa
    73561 gctgtaaatt ctgaaacttt atttaattta gttgttgatg aaaagtttgc gaatgaattt
    73621 tttaaaagta aaaaaattga aagactaaat aacctgtttc ctgaaaatgc aataaaagct
    73681 tatgtagata ataataaatc acgattatac aactggttta ttcccaaacg gttgcgagga
    73741 aaaatcaaaa ttggcgatca agtgaaagta attaatctaa atcatactaa gatcgttacc
    73801 gtaacggagt tgtatatagc tgaaaaagaa gagattacaa aaatgaaacc agttattaaa
    73861 atactagata acaaagagtg agtggaatat atggtagcaa aaaagaatac tctaaaagaa
    73921 gcttctgaaa aatatcaaga tatgaaaaga cgaggattaa taccaaagga caaaaaaggt
    73981 atatggagag aatttgttaa ggaagtcagt agtgatcgaa gtggcggtga ctttgttgga
    74041 cgatatacag caaaaggtta tagcaggcgc ttaaggatca ccgttgaata tggaacaaat
    74101 gaatcagcta cagagctgaa gcaaaggtac ttagatacac gaagagaagc ttcaaaaaaa
    74161 tatgatgatt tcaagagcag aggtctaatt cctaagaaga agaaggggat ttggcgtgag
    74221 tttttcaaag aagaagatag caatcggaat aagggagact tcattggacg atacacagca
    74281 aaaggctaca ctaagaattt agggatcaag gttgaatacg gaactggtga aagttcatgg
    74341 gaattgagaa atcgctattt aaatacattg ttagagaaat ataaagcaga attattggag
    74401 ttgttcgatg ttaatgattt tatcgagatg gctgaaaagt atggtcatga agaaggtttt
    74461 atgatcaatg acattatggt tattgataat tttacggatt tattagcact tgcgaaaaaa
    74521 gcaagggatt taagagaaac gcagatgtat ctattcagaa ataaaaacgg aagaaaccgg
    74581 agaactgaat cgagtgagat tgaagattac tacgatgcct ttacacacga tctgggagcc
    74641 tttgtagacg agataagtgg tgtaatggac aaatataggg tctagaataa aaaagccgga
    74701 gatgaacaga taaatgggaa acaatagcat atacacacct gaaatgcaga ataaaattaa
    74761 aagacttgtc agattagggt ggatgacaag aggaaaatta gattctttta gtacgatcaa
    74821 atatcttttg atggatattt accgtcagaa caagcaaaca ggaatacatt ttttgggcta
    74881 tgataagccg gaagatgcac ctttctttgt tccaagttca gcctatagag ccagtacctc
    74941 cggtagcatg tataacttgg atttgttcga ggaaggagca aagatgatcg aatatgattt
    75001 caacgaagcc tattcgagga tcatgagaaa ttatcctttg ccgtcaaaca cttatttgaa
    75061 agtaaaatat aatacagatc aagctatttt gagagcgata aatagaccaa aagtaagacc
    75121 gtatgaaaat ttaaaaacgt atatgttctt tttggttaat tttgaaggaa cagccaaaga
    75181 aggaacatat gctaatccaa aatcacagtc gatgtttgcg gattatggcg aaaatcccaa
    75241 aacagctaat gagcctattt ggttatcgga gattgagcta acacttatcc ttgattatta
    75301 tgatattaaa gagatggaag tcctagatag ccatacattt ttgacgaaaa aaggattact
    75361 caaagaatat tttgaaagaa tcgagccatt aaaaactgat cctgatacgt tgaagcttta
    75421 taaaaatctt agaacgaaag tatttggtgc tatcggacaa aaatcattaa gagaaggaga
    75481 aacaagcacc ttcgataaat acagtatgta taatcgagcg tattcctcca tggtagcagg
    75541 cgtatttaga gatcgtatgg ttagatatga acagaaatac gttcatagcg catatgggct
    75601 attaaaaatt cgtactgatg gattgtattt cagatccgaa gtaccagagt ttgaagagct
    75661 gtataaactt ggagtagtta agaaaaaagt tcatacaata tccaaagaag aagtcgaaaa
    75721 agctttagaa tttaaaaata aaggatttga aaataagggt tcctttggga aatctaaaga
    75781 tgaagttaag ggtgttgtga tagacgatga tttcgagttt gattttgact aaatactctt
    75841 tggaaaagat ggtaggaggt aaatatgaag aagaaaattg tggaaggaaa tgtaggtgtt
    75901 attattctaa aagattcaac tgactatgct aaatcaatgg cattaaaaga tgaaaaagtt
    75961 gcacgcatgg ataaagattt agttgaattt ctgatggatg atacagaaag attaaaaggg
    76021 gatcagtttt tgagtttaat gaaagacaaa ggcttaaaca catatggttt atttgattat
    76081 aagaaattag ctatagagtg ggtaaaagaa ggagaaatat tttttattga agaatgggag
    76141 ggtactgaga atttagttct tcatcagtat cttttgaaag cttaatctaa gtaaaacata
    76201 aggaataatt ttagaattgt tggaactatc ttttgaataa tttagtatga aaagaaatta
    76261 tacctcaaaa caaagtatct ttttaggttt aaggtacttt gttttgaggt ataattgggt
    76321 aaaaatgatt ttgaggtgat tttaatgagt ttaagtgtac aataccacaa tactatgaat
    76381 aacatagcat ttaaaaaatt ttcaaacgtt gaaatagacg tattttttgc tatatgttcc
    76441 caattagaag aaaaagggag tgacgaagtt tctttatcct tcagacaatt gaaagaacta
    76501 agcaatctca atatgatgac tgacagttct ttagtaaaag tattaagatc gctttataaa
    76561 aaaatggcaa cattatattt ttatagattg tcagaagatg gtagtgagac atgttttgtt
    76621 atttttaagg aatatagtat tgatacttct aagagcaata tagcaattaa aactaatgca
    76681 gaatatatgt atcttctaaa cgatttaact tcaaatttca ctatttttga gatgaaagag
    76741 tttactagtt tgagaagtaa gtactctaaa agtatctatt gcttgttgaa gcaaagtaat
    76801 ttaggaaaac aagttatcaa tattgatgag tttcgaaaat tacttgctgt accaaaaagt
    76861 tataaaatga caaatattga taaaaaaata ttagaaccag tctgcgaaga attatctata
    76921 tatttcgatg aattgagcat cacaaaagta aaaacaggga aaagtattgt ggcttttgaa
    76981 tttacgtgga ataagtaaaa caattccgac tagtggatgt tttccataac catcatcatt
    77041 caaaaataaa ggatttgaaa ataagggttc ctttgggaaa tctaaagatg aagttaaggg
    77101 cgttgtgata ggcgatgatt tcaagtttga ttttggctag attttttttg caacgtttaa
    77161 gagtaaacaa ggtaagaaat aagatcgtga agattgagag taaggaaaat agaggacgaa
    77221 tgtatgagaa cacactatat ttatttagaa gataaaatta tagatgaaat tccggcaaaa
    77281 agtcgagaac aagctagaaa attatttatt gaaaaataca aagagatcaa tggagatagt
    77341 gaagttccga aagtggtcgt aacagttaga aaaagacaaa taaaaaagag aagtacgttt
    77401 catgtcagcc ctgatatata taatcttata gagcaacata gaagtgaaga taatatttct
    77461 atctctcaat atattggtac agttattgat gaattgattt caggaaagta tgattatgct
    77521 tttgattttg aggatgaaaa ggattaccga agtgttgctg tctttcaatc tgattttgag
    77581 aagctaaaag actatgctgg caggagaaat gttaattttg caagactact agaagagttc
    77641 tactccgaag agttgggagt aggaaatgaa tacaagaaag aaaattatgc gaaattatct
    77701 cataagttat cccaagcgct taaagaagtg acagaagtta aaggttttag aaccatataa
    77761 aacagcatag ttctcaaata tgattagaaa ccctattaaa gagcaatatt aagccaactt
    77821 acttaaatcg tttaattaag aacagtaatc tcttttagtc agacttttag tctgactttt
    77881 ttgtatttcc aaaaatttat tctttacaaa aacgaacata cgtttgtata attgcttgtg
    77941 aatgggggaa taaaaatgtt tgattacagt agagaaccgg tgaatgacta ttttttaatc
    78001 gacatgaagt ctttcta
//
LOCUS       DAFEKH010000005        77355 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.005, whole genome shotgun sequence.
ACCESSION   DAFEKH010000005
VERSION     DAFEKH010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 77355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 77355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77355
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.005"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(524..751)
                     /locus_tag="LP386_000389"
     CDS             complement(524..751)
                     /locus_tag="LP386_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1917657.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            complement(760..1233)
                     /locus_tag="LP386_000390"
     CDS             complement(760..1233)
                     /locus_tag="LP386_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBL1917658.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            complement(1873..2046)
                     /locus_tag="LP386_000391"
     CDS             complement(1873..2046)
                     /locus_tag="LP386_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917659.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            2463..3029
                     /gene="amaP"
                     /locus_tag="LP386_000392"
     CDS             2463..3029
                     /gene="amaP"
                     /locus_tag="LP386_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBL1917660.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            3042..3230
                     /locus_tag="LP386_000393"
     CDS             3042..3230
                     /locus_tag="LP386_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBL1917661.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            3243..3800
                     /locus_tag="LP386_000394"
     CDS             3243..3800
                     /locus_tag="LP386_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBL1917662.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            3832..4074
                     /locus_tag="LP386_000395"
     CDS             3832..4074
                     /locus_tag="LP386_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBL1917663.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            4415..5629
                     /locus_tag="LP386_000396"
     CDS             4415..5629
                     /locus_tag="LP386_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HBL1917664.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            5660..5878
                     /locus_tag="LP386_000397"
                     /pseudo
     CDS             5660..5878
                     /locus_tag="LP386_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173391.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            6297..6770
                     /gene="dfrF"
                     /locus_tag="LP386_000398"
     CDS             6297..6770
                     /gene="dfrF"
                     /locus_tag="LP386_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HBL1917665.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            6897..7553
                     /locus_tag="LP386_000399"
     CDS             6897..7553
                     /locus_tag="LP386_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HBL1917666.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            7735..8265
                     /locus_tag="LP386_000400"
     CDS             7735..8265
                     /locus_tag="LP386_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBL1917667.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
     gene            8811..9053
                     /locus_tag="LP386_000401"
     CDS             8811..9053
                     /locus_tag="LP386_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HBL1917668.1"
                     /translation="MENELLENLGRLHTTELGVIRIKKNLSLNVENVIEWCKEKISLS
                     NAEITRKGKNWYITIDNCIITVNAYSYTVITAHKVK"
     gene            9050..9520
                     /locus_tag="LP386_000402"
     CDS             9050..9520
                     /locus_tag="LP386_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBL1917669.1"
                     /translation="MINFSIKELNAFAVIGQEVELTNYQKKNIQISTQFWRKFNSSLK
                     KAYLSQSGNWVKYAFMERRNGKLYYFCSIPQRTITPEGFLYKEIPSYKYLVVEHIGAM
                     DKIYETYGKIYEEIIPSTSYIPIKDIILHFEKYDYRFHWNSDNSVIEIWIPIQD"
     gene            9648..10862
                     /locus_tag="LP386_000403"
     CDS             9648..10862
                     /locus_tag="LP386_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBL1917670.1"
                     /translation="MNDKNFIEELRQKREEYGVTQTRLAVACGISREYYNRIEKGKQP
                     LNDELREIIEKQIERFNPQEPLFLLIDYFRVRFPTTDALAIIRDVLQLKSNYMLYEDY
                     GKYGYESKYVLGDINIMCSMQEHLGVLLELKGKGCRQMECYLLAQERSWYDFMLDCMT
                     AGGVMKRLDLAINDKAGILDIPKLKEKYKAGECMSYFRMQKDYSGTEKCGSDLPKNTG
                     ETLYLGSTSSELYMCAYQKNYEQYVKNGTEIEDTEIKNRFEIRMKNERAYYAVVDLLT
                     YRDAERTAFSIINHYVRFVDREDDKPKSQWITNDDWAWFVGENREPIRLTTKPEPYTL
                     QKALHWLQRQVAPTIKMVQALDRENRTTILKDMIEQAELKDKHKHLLQLEKSTIEERI
                     DTAVPQENDGIF"
     gene            11851..12060
                     /locus_tag="LP386_000404"
     CDS             11851..12060
                     /locus_tag="LP386_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA wybutosine-synthesizing protein 3-like
                     protein"
                     /protein_id="HBL1917671.1"
                     /translation="MNCLERFYRKGVCVIDNAVKTIQKKNGKCGIGNRGKTKIVVKEH
                     FSEKGKTMEELLTDVMLEKAKQTIA"
     gene            12172..13785
                     /locus_tag="LP386_000405"
     CDS             12172..13785
                     /locus_tag="LP386_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1917672.1"
                     /translation="MKQQIYNTALYLRLSRDDELQGESSSITTQRSMLRLYAKEHHLN
                     VIDEYIDDGWSGTNFDRPSFQRMIEDIEAGKINCVVTKDLSRLGRNYIMTGQYTELYF
                     PSHNVRYIAIDDGVDSEKGESEIAPFKNIINEWVARDTSRKVKSAFKTKFAEGAHYGA
                     YAPLGYKKHPDIKGKLLVDDETKWIIEKIFSLAYQGYGSAKITKQLRAEKVPTASWLN
                     FTRYGTFAHIFEGKPESKRYEWTIAHVKAILKSEVYIGNSVHNMQSTVSFKSKKKVRK
                     PESEWFRVENTHEPIIDKEVFYRVQEQIKSRRRQTKEKATPIFAGLVKCADCGWSMRF
                     GTNKTNKTPYSYYACSYYGQFGKGNCSMHYIRYDVLYQAVLERLQYWAKAVQQDEEKV
                     LNKIQKAGNAERIREKKKKASTLKKAENRQNEIDRLFAKMYEDRACEKITERNFVMLS
                     SKYQKEQIELEQQITSLREELSKMEQDMIGAEKWIELIKEYSVPKELTAPLLNAMIEK
                     ILIHEATTNEDNERIQEIEIYYRFIGRVE"
     gene            13820..15031
                     /locus_tag="LP386_000406"
                     /pseudo
     CDS             13820..15031
                     /locus_tag="LP386_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
     gene            15054..15980
                     /gene="glsA"
                     /locus_tag="LP386_000407"
     CDS             15054..15980
                     /gene="glsA"
                     /locus_tag="LP386_000407"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HBL1917673.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            16188..17648
                     /locus_tag="LP386_000408"
     CDS             16188..17648
                     /locus_tag="LP386_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917674.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIREIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            17869..19632
                     /locus_tag="LP386_000409"
     CDS             17869..19632
                     /locus_tag="LP386_000409"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HBL1917675.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            19716..20174
                     /locus_tag="LP386_000410"
     CDS             19716..20174
                     /locus_tag="LP386_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HBL1917676.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            20283..20966
                     /locus_tag="LP386_000411"
     CDS             20283..20966
                     /locus_tag="LP386_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBL1917677.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            21113..21727
                     /locus_tag="LP386_000412"
     CDS             21113..21727
                     /locus_tag="LP386_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HBL1917678.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            21743..21949
                     /locus_tag="LP386_000413"
     CDS             21743..21949
                     /locus_tag="LP386_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917679.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            22490..23620
                     /locus_tag="LP386_000414"
     CDS             22490..23620
                     /locus_tag="LP386_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBL1917680.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     gene            23712..24467
                     /locus_tag="LP386_000415"
     CDS             23712..24467
                     /locus_tag="LP386_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBL1917681.1"
                     /translation="MKVSQKIILSILLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEP
                     KSIPTTLNVALIGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGM
                     NKINAAYSYGGVDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSL
                     DLDGVYINKGEQVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFK
                     LPKAVGKLLGSIQTNLPESVLLDCGMDFLKDIC"
     gene            24525..26564
                     /locus_tag="LP386_000416"
     CDS             24525..26564
                     /locus_tag="LP386_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HBL1917682.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSYQATRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(26673..27824)
                     /locus_tag="LP386_000417"
     CDS             complement(26673..27824)
                     /locus_tag="LP386_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBL1917683.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(27978..28508)
                     /locus_tag="LP386_000418"
     CDS             complement(27978..28508)
                     /locus_tag="LP386_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBL1917684.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(28607..28957)
                     /locus_tag="LP386_000419"
     CDS             complement(28607..28957)
                     /locus_tag="LP386_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HBL1917685.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(29114..30643)
                     /gene="ahpF"
                     /locus_tag="LP386_000420"
     CDS             complement(29114..30643)
                     /gene="ahpF"
                     /locus_tag="LP386_000420"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HBL1917686.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(30653..31216)
                     /gene="ahpC"
                     /locus_tag="LP386_000421"
     CDS             complement(30653..31216)
                     /gene="ahpC"
                     /locus_tag="LP386_000421"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HBL1917687.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(31360..32022)
                     /locus_tag="LP386_000422"
     CDS             complement(31360..32022)
                     /locus_tag="LP386_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL1917688.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            32206..33852
                     /locus_tag="LP386_000423"
     CDS             32206..33852
                     /locus_tag="LP386_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBL1917689.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            33843..34925
                     /gene="uxuA"
                     /locus_tag="LP386_000424"
     CDS             33843..34925
                     /gene="uxuA"
                     /locus_tag="LP386_000424"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBL1917690.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(35033..36586)
                     /locus_tag="LP386_000425"
                     /pseudo
     CDS             complement(35033..36586)
                     /locus_tag="LP386_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            36734..37875
                     /locus_tag="LP386_000426"
                     /pseudo
     CDS             36734..37875
                     /locus_tag="LP386_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(38001..39080)
                     /locus_tag="LP386_000427"
     CDS             complement(38001..39080)
                     /locus_tag="LP386_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL1917691.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(39183..39623)
                     /locus_tag="LP386_000428"
     CDS             complement(39183..39623)
                     /locus_tag="LP386_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL1917692.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(39680..40090)
                     /locus_tag="LP386_000429"
     CDS             complement(39680..40090)
                     /locus_tag="LP386_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBL1917693.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(40270..40704)
                     /locus_tag="LP386_000430"
     CDS             complement(40270..40704)
                     /locus_tag="LP386_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL1917694.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(40804..41652)
                     /locus_tag="LP386_000431"
     CDS             complement(40804..41652)
                     /locus_tag="LP386_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL1917695.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            42041..43807
                     /locus_tag="LP386_000432"
     CDS             42041..43807
                     /locus_tag="LP386_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HBL1917696.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            43909..45168
                     /locus_tag="LP386_000433"
     CDS             43909..45168
                     /locus_tag="LP386_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBL1917697.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            45315..46616
                     /locus_tag="LP386_000434"
     CDS             45315..46616
                     /locus_tag="LP386_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1917698.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            46619..47470
                     /locus_tag="LP386_000435"
     CDS             46619..47470
                     /locus_tag="LP386_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1917699.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            47483..48298
                     /locus_tag="LP386_000436"
     CDS             47483..48298
                     /locus_tag="LP386_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HBL1917700.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELKLSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            48449..49615
                     /locus_tag="LP386_000437"
     CDS             48449..49615
                     /locus_tag="LP386_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL1917701.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPTQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            49845..50492
                     /locus_tag="LP386_000438"
     CDS             49845..50492
                     /locus_tag="LP386_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBL1917702.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            50576..51520
                     /locus_tag="LP386_000439"
     CDS             50576..51520
                     /locus_tag="LP386_000439"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HBL1917703.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            51655..53106
                     /locus_tag="LP386_000440"
     CDS             51655..53106
                     /locus_tag="LP386_000440"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HBL1917704.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            53127..53963
                     /locus_tag="LP386_000441"
     CDS             53127..53963
                     /locus_tag="LP386_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBL1917705.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            53963..54622
                     /locus_tag="LP386_000442"
     CDS             53963..54622
                     /locus_tag="LP386_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBL1917706.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            54748..55437
                     /locus_tag="LP386_000443"
     CDS             54748..55437
                     /locus_tag="LP386_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917707.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            55443..56399
                     /locus_tag="LP386_000444"
     CDS             55443..56399
                     /locus_tag="LP386_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HBL1917708.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHRIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            56443..56955
                     /locus_tag="LP386_000445"
     CDS             56443..56955
                     /locus_tag="LP386_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1917709.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(57211..57759)
                     /locus_tag="LP386_000446"
     CDS             complement(57211..57759)
                     /locus_tag="LP386_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL1917710.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(57848..59029)
                     /locus_tag="LP386_000447"
     CDS             complement(57848..59029)
                     /locus_tag="LP386_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HBL1917711.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(59265..60773)
                     /locus_tag="LP386_000448"
     CDS             complement(59265..60773)
                     /locus_tag="LP386_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HBL1917712.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            60932..61123
                     /locus_tag="LP386_000449"
     CDS             60932..61123
                     /locus_tag="LP386_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917713.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            61326..62243
                     /locus_tag="LP386_000450"
     CDS             61326..62243
                     /locus_tag="LP386_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HBL1917714.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            62236..63305
                     /locus_tag="LP386_000451"
                     /pseudo
     CDS             62236..63305
                     /locus_tag="LP386_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            63453..63971
                     /locus_tag="LP386_000452"
     CDS             63453..63971
                     /locus_tag="LP386_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917715.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            63952..64344
                     /locus_tag="LP386_000453"
     CDS             63952..64344
                     /locus_tag="LP386_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HBL1917716.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            64420..65355
                     /locus_tag="LP386_000454"
     CDS             64420..65355
                     /locus_tag="LP386_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HBL1917717.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            65488..66267
                     /locus_tag="LP386_000455"
     CDS             65488..66267
                     /locus_tag="LP386_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBL1917718.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            66260..66577
                     /locus_tag="LP386_000456"
     CDS             66260..66577
                     /locus_tag="LP386_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBL1917719.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            66821..68431
                     /locus_tag="LP386_000457"
     CDS             66821..68431
                     /locus_tag="LP386_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBL1917720.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            68588..69436
                     /locus_tag="LP386_000458"
     CDS             68588..69436
                     /locus_tag="LP386_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBL1917721.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            69667..70146
                     /locus_tag="LP386_000459"
     CDS             69667..70146
                     /locus_tag="LP386_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917722.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            70179..72407
                     /locus_tag="LP386_000460"
     CDS             70179..72407
                     /locus_tag="LP386_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL1917723.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            72536..74179
                     /locus_tag="LP386_000461"
     CDS             72536..74179
                     /locus_tag="LP386_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBL1917724.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(74252..74797)
                     /locus_tag="LP386_000462"
     CDS             complement(74252..74797)
                     /locus_tag="LP386_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HBL1917725.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(74820..75305)
                     /locus_tag="LP386_000463"
     CDS             complement(74820..75305)
                     /locus_tag="LP386_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBL1917726.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(75295..76107)
                     /locus_tag="LP386_000464"
     CDS             complement(75295..76107)
                     /locus_tag="LP386_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HBL1917727.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(76246..>77355)
                     /locus_tag="LP386_000465"
     CDS             complement(76246..>77355)
                     /locus_tag="LP386_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HBL1917728.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT        26028 a        13422 c        15200 g        22705 t
ORIGIN      
        1 cattattatc aaaataatgt taaaaataaa aaagaattgt ccatcactgt tattcaaatc
       61 attttatcaa aactacatag taaatgttaa aaagcaacat gacataatat atagaaggct
      121 ttacagtata tatgggagct tactaaaaaa gaatggagta agagttaaca caatgggcca
      181 ttagctgaag ttttaagcac ttcaaggtat gaaacagaat ggcctgtaat actacatgat
      241 tatttagact gctcaaactg ctatcagtct ggtggaatga ataaagtatt atactaaaag
      301 cagatccaac tacaacgtaa caggaaacca gttgtatcag gaaaagtgat agtacatgga
      361 gaagaaaagg ccccctttgt atgagtcagt acatatctta tttatagata aaacggtatt
      421 caatcgaaat aaaaaatctg aataatagac gtaaataact tctaaaagtc tcacacatct
      481 atcattcaga ttatttttta tttactgttt gttctacttt attttattct tctggtatag
      541 tattcgagtc atttttatag gtcaacaaat cacctggttg acactccaaa acttggcaga
      601 ttttttcgag agtggaaaaa cggatggctt ttgcttttcc attttttaga atagagatgt
      661 ttgccatcgt aatgcccact ttctcactca attcagtcac actcattttt ttttgagcta
      721 atactacatc taaattaacg ataattgcca tgtcgcacct cacactgtca aatcatgatc
      781 tgtcttaagt aaaatcgcat gttcaagcag tttttccagc acgcttgtta atgtgtatac
      841 tgcaaaagga atgaatacga cagcgattcc taccaacatc aaacctggag catcgtctaa
      901 atccgctact ttcataaatt taggaagtaa gccaaaaaag gcgaaaccaa taaacaaaat
      961 ggttcgttcg atttttttta gtatgtttaa gctttgagtg gaaaaagctt ggttatcttc
     1021 gatttttttc aatagtttca ataagaaata agcaataacg atccctagga gaagggcaaa
     1081 gtaaatgaca gaaacaaata atgtggtctg ccaatcaaaa ttgaatcctt tttcgcttgt
     1141 agcgatctga gtataaaaaa gtacgccgaa caaaataaat acggcactta tacctaaaac
     1201 gacaaatttt aatagcaatg ttttaaattt catttttatc cctcttttat ctttgatagc
     1261 taaaatatag cagaataatt attgtaaaac aactattttt tatcgaaaaa caataaaaat
     1321 atatcgttta taaaaaatga tagagtatga aggtgtggag tgcatttaac agcttttttt
     1381 gattgtaaga aacatttaaa accagttatt ttagattcta tgtgtgtctc ttctataatg
     1441 ctagtttaga tgcctgggat tatattggac aatacagttg gaggattttt tattatctag
     1501 cgaagagaag tgtaagttaa cagaactgta tgagaaaaaa gacaactacg tagtagctaa
     1561 ccgattcatt aattttttca agttcatgtt tatttacgta tcagaatttt tcttattcaa
     1621 tggtttggtg taatcaccac ttatttgtcc tttattgctt atacaatgtt atacaaaagg
     1681 aaaatcaagc attgacgcat ggggtggtac tatctagctg aaatagctta ataagcgcaa
     1741 gtagatgcat tggattagtt tataaatcaa aagtgttaga ggtattaaga agaagtagaa
     1801 aaataaaatg gattgccgaa taaaaagtac cataaatcct aaaacatgtg ccaacagata
     1861 gatggcacat gtttattttt ttcgataatt ttgtaacaaa aatacgaaga tgaaaaagaa
     1921 tagagattcc cataatgtag tagtccaact gaattcttta ctgataccaa ataccatatt
     1981 tcctagattt gatacaatca aatagccaat cgttatgatc aatgaatagt acaatctttt
     2041 catcatagga catacctcgt ttttatttat aagaatagta taaaccaaag aagtgaataa
     2101 gaaaaatgat aatataaaaa taaagtaaga acgcattaaa gtaactaaag ttatttattg
     2161 tattttttaa ttctccgaaa aaatttaata aataaataga atcttgtaat aataactgag
     2221 cataatcttt gcaattttta atcttgaata atatccttta agtatagcca gcaatcaaaa
     2281 gtaaatagag aataagtaag caattgttat ttcagtatca gactggcaat aaaacgccgt
     2341 tatgatccag caatgtttgg tagcgcttta tttactgatg ctatgctaac tgttcgctat
     2401 ctatactgtg attgtcggta gagttattta cagggtaaaa ataagtttat aggaggtgga
     2461 aaatgaataa ggggttaaaa ataatcggtg ttatcatgag tttactgcta ctttcagtat
     2521 ttctagcgat tgcgttgatc aatgcgccgt atattatgcc tgaacaattg gaacgatttc
     2581 gcttctttac tttaacgaat tactacatgc aacaatatat tttctgggca gctgtagtat
     2641 ttgccgttct tgctattatc atcttgctag tcgttctttt ctatccaaag tcaagaggaa
     2701 ctttcgttat gaaacgggaa gatggcaaac taacaatcga caaaaaagcg atcgaagggt
     2761 tggtacgttc ccatttacac gaagaagagt tcattcattc acctaaagta cggatacgtt
     2821 caacgaaaaa tcgaatccat atccatgtca acggagactt gaaacgaact tcttcattag
     2881 tagggaaaac aggtgtattg atgcaagata tcgaagaaga agtaactaaa gtactcggaa
     2941 caaaagaaac ggtcaaagtg gcagtcacat acagcggtta tgaagaacaa gaagatacaa
     3001 gagactacaa gcactctcga gtggaatagg agggccaaat aatgaaagaa ctattttcag
     3061 catacaagct ccctattatc tttgggggtc ttggactact gctagctgtt ttatggttaa
     3121 cgattggatt tttcaagaca ttgttgatca taatcatgac agcaattggc gcaggaatcg
     3181 gtttttattt gaaacagtca ggaatagttg atcaattttt taaatcatag gaggaaacaa
     3241 agatggaaaa caaaaacatg aatacaacaa atggatcagt tttggcaaat gaaaaaggag
     3301 aaaaccgcat gatgaatggt gaattgactt atgaagacaa agtcatccaa aaaatcatcg
     3361 gttatgcatt gaaagatgta gatggtctat tgacattaga tggcggattt ttctcaaata
     3421 tggctgaaaa attagtcaac acagataacg taacagcagg tatcaataca gaagtaggta
     3481 agaaacaagt agctgtggat ctagatgtga tcgtagaata cggtaaagac atcgaagata
     3541 tttacaacca aatcaaagaa ttgatcagta ctgaagtaaa caatatgaca catttagatg
     3601 ttatcgaagt gaatgtgaat gttgcagaca tcaaaacaca agaagaatac caaaaagatc
     3661 aagaaacagt acaagacaaa gtaacagaag cagcaaaatc cacaggacaa tttgcttcac
     3721 gccaaacaga taaagcaaaa tctgctgtag gcaaaggtgc acaaaaagtc aaagaaaata
     3781 acgaaccacg tgtacaataa gaagtaagaa gtcagttagg aggaatttaa aatgggattt
     3841 atttgggcat taatcgtcgg cggtatcatt ggagcaattg caggagcaat cacgaataaa
     3901 ggatcatcaa tggggatcat cgcaaacatc attgctggtt tagtaggttc agcaattgga
     3961 caagctttac taggaacttg gggaccaaca attgcaggaa tggctatcat tccatcattg
     4021 atcggtgcaa tcattttagt attagtcgtt tcattctttg cacgtaaatt ataagcaaat
     4081 tgaagaaaaa cttatgttga aatgaagaac aaatttgaga accgtagcga cactcgctgc
     4141 ggttcttttt tatatatttt atatgaagta ttctttattc cttatgaaaa aatatcttta
     4201 aaaataaaaa aagacgaaaa taaacggttt tctataaaaa gaagaccgtt tattttttgt
     4261 ctttatttgt gtgaaaaacg aaaaagagca caacacatca agcttttatt aattgtctgt
     4321 cttttataaa tgcaagtatt aattcaaaaa aacagaagaa aaaaacaact acaccttctt
     4381 ttatactcgt aatcgtagaa aggaggcgaa aaaaatgaat acattaccta tcaatacagg
     4441 agatacagca ttcatgattt tatgtacagc aatggtttgc ctgatgactc ctggtctagc
     4501 ttttttttac ggcggattag cacggaagaa taatatacta acgatcatgt ctcaatcttt
     4561 tctctccgtt gggataacaa cgattatgtg ggtatttggt ggattcggat tggcctttgg
     4621 acgggatatc ggcggtgtta ttggaaaccc ggcagatttc tttttgatga gacatgttac
     4681 aagcttcccc aacatgtttc atggtgcaac gattccattt ttaatgttct ttctttacca
     4741 actgatgttt atcgtgatta ccgttccttt gatgacagga gcttttgcag ggagattgaa
     4801 tttaaaaggc tatattatac ttgttatttt ttggaatctg ctgatttatt tccctgtttg
     4861 ccactggata tggggtggcg gatttttgga tcagatggga tttagagatt tcgctggtgg
     4921 agcagtcatc cacacgacag ctggattcgg ctctttagca tgtatcctca cacttggtca
     4981 aagaaagatt cctttaggag aaagaagtca gcatagcagt cttatggcag ctgctatcgg
     5041 tacaggactg ctttggtttg gctggttcgg ttttaattcc ggtggtgcac ttcgagcaga
     5101 tgaacaagca gtcaatgcat ttggttcaac attcatcgct cttgcatttg cgatgattac
     5161 ttggctgatc attgcaaaag taaaaggaaa tggctttgat tttgtcgacg tactaacagg
     5221 atccgttgct ggattggcag ccattacgcc ttgtgccggt tatgtagaag caaaaagtgc
     5281 catgctgatt gggatcattg cgggtatcgt ctgtcatgct gctgttgatt ttcgtaaaaa
     5341 gaaacaatgg gatgatgcac ttgatgtgtg gggtgttcat ggcatgggcg gattcacagg
     5401 tacgattctg atagggatct ttgcatctaa cagccattta ctaacgaatc caagcagctg
     5461 gtacttctta gggattcaag tgattggtgt catcattact gccgtgtatg cctatgtgct
     5521 gacaacagtg attttaaaat cggcgatgca ctttacaacg atcactacta caaaagaaga
     5581 acaagaagaa ggattggact ttttcttctt tggcaacaaa ctcaattgaa acaaattcaa
     5641 atagaaaaga ggaagattca tgcaacaaag caaaacgaaa attcctgcaa aaaaattaac
     5701 gttctttggc tttttggcta tgaccatctc aatggtcgtt tcattatatg aatatcccac
     5761 attcgcgacc tcaggcttca gcttagtatt tttcttgtta ttaggcggtt tgctatggtt
     5821 tatccctgtg gcattgtgcg cagcagagat ggcaacggtg aaaggatggg aaaaaggtgt
     5881 ttcccaaaca aaaagatatt aagaaacagc ccatgtttac ctgcttgcaa acaaaagaat
     5941 attgctacta gactaagaga tactacataa gtgtgttggt atctcttttt tgttgccgtg
     6001 aaacagcaga ctatttcatt tctgcttgat taccttaaaa cttattagtc tatggtttgt
     6061 caagggcttg ttgcgtgaga aatgctgaat atcacccttt acaaaacata ggctgataag
     6121 taacttttca aaagcagaaa agaaatggca atgcttataa caatatgata taatgcagat
     6181 gaagacaaaa aaggaatttg tcgagctggt tagttcgaga taattttgag tttgttaaga
     6241 tgtggtgcac ttgatggaat cacaggtacg acatcatatt atggaggatg aaatagatga
     6301 taggtttgat tgttgcgagg tcaaagaata atgttatagg caagaatggt aatataccat
     6361 ggaaaataaa gggagaacaa aagcaattta gagagttaac aacgggtaat gtggttatta
     6421 tggggcgaaa gtcttatgaa gaaatcggtc atccgttgcc taatagaatg aatattgttg
     6481 tttccaccac aacagagtat caaggagata atttagtttc agttaaatca ttagaagatg
     6541 cattattatt ggctaaagga cgagatgtat acatatctgg tggatatgga ctatttaagg
     6601 aagctttgca aatagtagat aaaatgtata tcacagaagt agatttaaat attgaagatg
     6661 gagatacatt ctttccagaa tttgatatca atgattttga agttttgata ggggaaacac
     6721 ttggtgagga agtgaaatat acgagaacat tttatgtaag gaaaaaatga attgagtaaa
     6781 ttttggattt agggtgtttt cataaatata ttgcttttta tgcatatata aattgttgta
     6841 agacaaattc cagtttgtat ggggcgataa aatcagaatt tgagagagga ttgaatatga
     6901 ataaggaatg gtctgaactt aataaaacaa tgcaggcaca aataaaaaag aaagatactt
     6961 ataagagggg tattgatact ttacttactt tacgaagtca gttaatacaa accttagtat
     7021 ctttcaaaga agaattatgc agagaagatt ttaactcaat ccccttcata aacgctgatg
     7081 gttatcatag taagacgatt gcttattcta tttggcatat tttccgcatt gaagatatag
     7141 ttgtgcatac agtgataaat gaagatgaac aagtattttt tgcaggcaat tatcaagagc
     7201 gtatcaattc acctatcatt acaacaggaa atgaactcat gaaacagcag attgcagact
     7261 tttcaaaaca gcttaatctg gaagaattat atttatatat tttcgaagta tgggaaagca
     7321 ctgagaaaat gcttgaacgg ttatcttatg atgaattgaa aagaaaaata ccgaaagaaa
     7381 gaaaaggata cttagaatcg ttgaatgtag taaacgacaa tgaaaaagca atttggctga
     7441 ttgattattg gtgtaataaa gatatttgtg gactaattca aatgccgttt tcaagacatt
     7501 ggattatgca cacagaagcc tgtttgcgta taaagaacaa gatacattca taggcaaaaa
     7561 tttcagtttg tagaactaag gaaattggaa tttaaggagg aataaagtat ggttagtgat
     7621 tttataagag cagcatttcc atggatttta atgggtttat ttgtagcaat cagttgttcc
     7681 cttatgagta aaaaagagaa ataaattcct gtttgtattt ataaaagaga aaaaatgaga
     7741 aaagtagttt tatttattgc catgagcctt gacggatata ttgcggacgg taatggtgga
     7801 gtagcttggc taaatggtca tggaaatgac aatgaaaaca tcgacactta tacagaattt
     7861 accaaagata tagatactgt cttaatgggg tggaatactt ctcatcaggt tgttactgaa
     7921 ctttctccgc aagaatgggt atataataaa tttacaactt atgtattaac acataaagag
     7981 tgcaattctt cccaacaaat tcattttaca agtgaaaatc ctgttttatt attggaacgg
     8041 ctaaaacaag aagcaggaaa ggatatttgg atttgtggcg gagcaaatct tgttcagcag
     8101 ttggtaagca aaaatatgat tgataaatat tacatttctg ttattcctac tctgttagga
     8161 aatggggttc gtcttttggg caacatagac agggaaataa agttaaggct ttgtaaaaca
     8221 cagacttata acggaataac cgatttgatt tatatgcgta gataactaga gagaaacaga
     8281 aaagctgtta aaccgacgga gcgatccgac cacgttggcg ggaaaatcct taagattttt
     8341 ccgccatgct tgcaaggggg cggttcgctt cggcggttcg gcgagcttgc gagccgttca
     8401 aagcccccgt tatctaacaa ggggggcaca aaaaacaaga aacactatac actaacaagc
     8461 ggaaaacgct gtatttataa ggcaaaaccc catttttaca gtagtgatat aaattgtacc
     8521 tatatcacta tgaaaattga atagtaaata tgagaaagac agttgatttc aaaaaataag
     8581 aaattgattg tcgttttctt ttgcagaaat ttaagtgcag gcaattatgg tagttgtcgt
     8641 aattgctgtc agctcagtgt ttatcactga tggtgtgaaa gatttacggt tggagatgtt
     8701 caataagatt attggtgctt aattattttt attgtagtgc tgatatgaga atgttataat
     8761 tggggtataa aacatacaaa taaatttgct gaaaaatgag gtatcaaaat atggaaaatg
     8821 aattactgga aaacttagga agacttcaca caactgaact tggcgttatt agaattaaaa
     8881 agaacttatc tttgaatgta gaaaatgtaa ttgaatggtg caaagaaaaa attagccttt
     8941 ctaatgcgga aatcacaaga aaaggaaaaa actggtatat aacgattgat aattgtatta
     9001 taacggtaaa tgcgtacagt tataccgtta tcactgctca caaggtaaaa tgataaattt
     9061 ttctataaag gaattaaacg catttgcagt tattgggcag gaagtagaac tgactaatta
     9121 tcaaaaaaag aatattcaga ttagtacaca gttttggaga aagtttaaca gtagtttgaa
     9181 aaaagcgtat ctttcacaat caggaaattg ggtaaaatat gcttttatgg aaagaagaaa
     9241 tggaaaactt tattatttct gttctattcc ccaaagaacc attaccccag agggctttct
     9301 gtataaagaa ataccgtctt ataaatattt ggttgtggag catattggtg ctatggataa
     9361 aatatatgaa acttatggca agatttatga agaaattatt cctagtacat cgtatattcc
     9421 tataaaagat attatcctac actttgaaaa atacgattat cgttttcatt ggaatagtga
     9481 taattcagtt attgaaattt ggatacctat tcaagattag aagcaatttt atatccatac
     9541 acacaaagca gttagtctta ggattgactg ctttttctat acagattttt aatgacaggc
     9601 aattatcaat tatggtagtt gccttttttg attggaggaa ttgaagaatg aatgataaaa
     9661 actttattga agaactaaga caaaagcgtg aggaatacgg agtaacacaa acaaggcttg
     9721 ctgttgcctg tggtatcagc cgtgaatatt acaaccgcat tgaaaaagga aaacagccat
     9781 tgaatgacga attaagagaa atcatagaaa aacagattga gcgtttcaat ccgcaagaac
     9841 cactattctt attgattgat tactttcgtg tccgctttcc tactacggac gcattggcga
     9901 ttatccgtga tgtattacaa ctgaaatcta attacatgct ttatgaagat tatggaaaat
     9961 acggatatga aagcaaatat gtacttggcg acatcaatat catgtgttcc atgcaggagc
    10021 atttaggtgt tttattggaa ctgaaaggca aaggctgtcg gcaaatggaa tgttatctgc
    10081 tggcacagga acgctcatgg tatgacttca tgctggattg tatgacggct ggtggtgtga
    10141 tgaaacggct tgatttggct atcaatgata aagcaggaat attggatatt ccaaagttaa
    10201 aggaaaaata caaggctggc gaatgtatgt cctacttccg tatgcagaaa gattacagcg
    10261 gtacagaaaa atgcggtagc gatttaccaa agaatacagg agaaacctta tatctcggtt
    10321 caacaagtag cgaattatat atgtgtgctt atcagaaaaa ttatgagcag tatgtcaaga
    10381 atggcacaga aattgaagat acggagatta agaaccgttt tgaaatacgc atgaagaacg
    10441 aacgagccta ttatgcggtt gtagatttac tgacctatcg ggacgctgaa cgcaccgctt
    10501 tttctatcat caatcattat gtccgctttg ttgacagaga ggacgacaag ccaaaaagtc
    10561 aatggataac aaatgatgat tgggcatggt ttgtagggga aaacagagag ccgatacgct
    10621 taaccacaaa gccagagcct tacactttac aaaaagcgtt gcattggcta caaagacaag
    10681 tcgcaccaac cataaaaatg gtacaggcat tagacagaga aaatcgtaca acgatactga
    10741 aagatatgat tgagcaggca gaactaaaag acaagcataa acatttatta caattagaga
    10801 aatcaaccat agaagaacgt atagataccg ctgttccaca agagaatgac ggtatttttt
    10861 aatgtaattg aaaaatttca gatttagtca gcaaagagct gttttcattc cctatgtgaa
    10921 gtgaaagaag aaaaataaat tttttattaa atctgcaaca aaatggctac ttgcgtacag
    10981 atatggtgcg agaaaaggaa atctaaactt tttttgaaaa taggtcatta aatcggggct
    11041 tgctgtccct atatgaagtg aaagaagaaa aaagttttga aaaaatgacg gaaattcgtg
    11101 attagtggac agtcttctgt gaaaagagga aaaacatcat cattttgtat tcaaacaggc
    11161 attagcagtt gagtgttgat gtgaaaagat gaaaatactt tgttctcaac ttaacaattt
    11221 aaggtttccg ttccctatat ggtgcaaaga aaatatttca ttctattgtt ggcagtaacg
    11281 gtatggtttg ggtagttagg gtgtgaaaag gaaaatattc ttttttcatc atcaacttag
    11341 caaaatgaca ttttctatcc ctatatggtg catgaaaaga agttaaaatt tttccattta
    11401 aacttagcaa atggacgttt gctgtacaga tagtagtgaa aaaggagaaa atcaaccgtt
    11461 gattgccaaa atgaaccgtt ccatttgtac taataatgga aaaagttttg gattttggtt
    11521 acgtttctcc tcttttccaa cgcgatatat aggaaagacg atttttttct ttcaatcgtt
    11581 ctttgacaac tgaataaagc tattcaatac gtttgacaga cagctagccg ttgaaacaaa
    11641 tacgccacga cctttcccct gcaagagcga gcgaaaacct atttgtgttc ttgtaaaaga
    11701 tttgtcctct tttatcgcca tgacctgtac tgtcagataa tgatactccc gtacagccac
    11761 agcttgagca ttaagagcgt cgcacgcaat gggtacggct acataagaac tatgcagagg
    11821 tggaactcct gtgggctatg acaaaagccg ttgaattgct tagaaagatt ttacagaaag
    11881 ggggtatgtg ttattgataa tgctgtaaaa acaattcaaa agaaaaatgg caagtgtggc
    11941 attggcaaca gaggaaagac aaagattgta gtaaaagagc atttttccga aaagggcaaa
    12001 acaatggaag aacttctaac tgatgtcatg ctggaaaaag caaagcagac aatcgcataa
    12061 aatcggtgca gttgtaagaa atagattgaa tgacaaaaag tacccgtgtt atactttact
    12121 tgcaagcagg tattgtaaac acgggttagt tataaaggag gataactgac aatgaaacaa
    12181 cagatttaca atactgcact ttatcttagg ttaagccgag atgatgaatt acagggcgaa
    12241 agttccagca ttaccacaca gagaagtatg ttgcgtttat atgcaaaaga acatcatttg
    12301 aatgtcattg atgaatatat tgatgacggc tggtcgggaa caaattttga cagaccgagt
    12361 tttcaaagaa tgattgagga tatagaggca ggaaaaatca actgtgttgt aacgaaagac
    12421 ctttcccgtc ttggcagaaa ttatattatg acaggacaat atacagaatt gtatttccct
    12481 agtcataatg tccgctacat agcgattgat gacggtgtag acagcgaaaa aggcgaaagt
    12541 gagattgcac catttaagaa catcatcaat gaatgggtgg caagagatac aagccgtaaa
    12601 gtcaaatcag catttaagac aaagtttgcg gagggggctc attacggtgc ttatgctccg
    12661 ttaggatata agaaacaccc tgacatcaaa ggaaaactgt tggttgatga tgaaacaaaa
    12721 tggattattg aaaaaatctt ttccctagcc tatcaaggtt acggaagtgc aaaaatcaca
    12781 aagcagttaa gagcagaaaa agttccgaca gcgtcatggc taaattttac aagatacggt
    12841 acttttgcac atatctttga gggaaaaccc gaaagtaagc gttatgagtg gacgattgct
    12901 catgtcaagg cgatattgaa aagtgaggtt tatatcggaa acagtgttca caatatgcag
    12961 tctacggtat cgttcaagag caaaaagaaa gtgcgtaagc ccgaaagtga atggtttcga
    13021 gtagaaaaca ctcacgagcc gattattgac aaggaagtgt tctatcgtgt gcaggagcag
    13081 ataaaatcaa gacgcagaca gacaaaggaa aaggcaacgc cgatttttgc agggcttgtc
    13141 aagtgtgcgg attgtggttg gtctatgaga tttggaacga ataagacaaa taaaacgcct
    13201 tacagttatt atgcttgcag ttactacggg cagtttggca aaggtaattg ttctatgcac
    13261 tacattcgtt atgatgtgct gtatcaagcc gtattggaac gcttgcagta ttgggctaag
    13321 gcagtacagc aggacgaaga aaaggtattg aacaagatac agaaagctgg caatgcagag
    13381 agaatacggg aaaagaagaa aaaggcaagt acattgaaga aagccgagaa cagacaaaat
    13441 gagattgacc gtttatttgc gaaaatgtat gaagatagag cctgtgagaa gataacagag
    13501 cgaaattttg tgatgttgtc cagcaagtac caaaaagaac agatagaact ggaacagcag
    13561 ataacaagcc taagagaaga actaagtaaa atggaacagg atatgatagg tgctgaaaag
    13621 tggattgagt taatcaagga atattccgta ccaaaggaac tgacagcacc attattaaat
    13681 gccatgatag aaaaaatcct catacatgaa gcaacaacga atgaggataa cgaaagaata
    13741 caggaaattg agatatatta ccgatttatt ggaagagttg agtaatcaac aagagtaata
    13801 tttttaacta agggaaaccg gcggtgtcta tacttgggtc agtcgcacat tgggaaaacg
    13861 attcggtttt gccgcaatct ttttccaatg gtttgagata acagttggct acttgaccat
    13921 gctgtatttc ttaactggtg cattatccta tgcaacgggt attggtgcta tacaaaacaa
    13981 taaatatctg aaattggcaa tcctattgat tattttctgg gctattttac tctcacagtt
    14041 aaaaggaacc aaatacactt cattgattgc tcggatcggt tttgtagctg gtatcttgtt
    14101 gccagcatta gtcttgtttg gcttagggat ccattatgtc gcttcaggcg ctccactaca
    14161 aacgatactg tctatgaaaa cattgattcc tgatttttcg aaattgccta cgctggttgt
    14221 ttttgtttcc tttattttag catatatggg cgtagaaaca tctgccagtc atgcaaatga
    14281 aatggaaaac cctaaaaagg attatccatt agcaatgttt gtattggtta ttctggcaat
    14341 cattttagat acttttggcg gattgaccgt cgctactaca gtacctcaac atggtttgtc
    14401 tcttaataca ggggtgattc aatcgttaga attcctatta agacacattg atccaaatct
    14461 tgcatggatt gcgaaaattc ttgcgattct tgtttgttta ggtgtcatcg gagaaattgc
    14521 ttcttgggta acctctcctt caaaagcact tcacgtagca gcagaagaag gattacttcc
    14581 tgaatatttt gcaaaagaaa acacacacgg tgttcctgct catttgatga tcgcaaatgg
    14641 gatcgttgca acaatctggg cagccgtctt tacattaagc ggcgggggga ataatctttc
    14701 atttcttgca gcgatgtcat tgactgttgt aatctacctg atgttgtact ttatgttttt
    14761 cgcgggctat ttgaagctgg tttttaaaga tgacagtctt gaaagagcct atcaggttcc
    14821 aggcggaaaa gttgtaaaag taatcgttgc ttgtttaggt cttttgactt cactttttgc
    14881 tttttgtatc tcatttgttc cacctgctag tatcgcagct ggacagcatg ggatttatga
    14941 aacgattctg attgtttctt atcttatcgt cttagttatt ccatttacga tctacgcatg
    15001 ccgtcataaa ttccagcatg cagaaaaata aaaaatgaaa gctggttatt caaatggaag
    15061 taaaagaatt agaacaattg attggaaaaa atttccacta ttatcaaaca ggacaagtgg
    15121 cggattacat tccagcatta gctgaagtgg atcccaaaca attaggtatg gcgatttatg
    15181 atttggatac aaaacaactg attgagggag gagacgccga tgtgcgcttt gccatcgaaa
    15241 gcatgtcaaa agttcccgta ttgttattag caatcaaaga caacggaata gaaaaagtct
    15301 ttcaaacaat caacacggaa ccaaccggtt ttgccttcaa ttctatcatg aatatggaaa
    15361 tcaatcatcg caaacatcca atgaatcctt ttgttaatgc aggagcgatt gcaacaacct
    15421 cgttgattgc cggtaaagat gcagatgaaa aatttgagcg aatcttgtca tttatgaaag
    15481 agatctgtga tgatcctaat atcacattga atgaagaaat ctatcattct gaatcaagaa
    15541 caggtgatat caatcgctct cttgcttact atatgaaagg taatcaaatg atcgaaggag
    15601 acgtaccgga gatactcgat gcttatttca gacaatgctc cctcaatgtc accgctacag
    15661 gcatagcaaa attagctgct gtgctggcaa ataaaggaat tgctccttgg aatggcaaac
    15721 aaatcattac tgaagaaagt gctacaatcg tcaaatcaat tatgacaact gctggtttgt
    15781 atgatgaatc aggagagttt tccgtccatg ttggtgtacc tgcaaaaagc ggtgtaggcg
    15841 gcgggttgat ggcagctgtg ccaaatcgtt acggcatagg tgtcttcagc ccggcactag
    15901 atccatttgg taacagcgca gctggtatcc aattgttgaa agatgtagtc aaagaactag
    15961 acgctgacat ctttgaataa ccattcttga aagaggctgg ggtaaaagtc caaacggctc
    16021 aaagctacct acaatgaggc tgaaattgtg agcttgtttg acttttgtcc cagtttcttt
    16081 ttttattggt ttttgaaagg gcttttctaa ataaaaagga aacaaaaata cgatttacag
    16141 atatgattaa ataaaatcat aagaaaaact ggaggcgtgt atcaggaatg ctggaaaatt
    16201 acatcgagcg aaatatattt agaaaagtgt atctgtgtga acaattattt gaattccaag
    16261 aaatagacat cgaacaaaca gctatttctc taagggtgac tacaccaacg atccttcacg
    16321 atctagaaag tctagccgag tgtctagaat attgtataaa agaacaagta agagagaagc
    16381 ataagtataa actcgtattc aaacatggta ttgctctttc tgagctcaca cagtttctgt
    16441 acggtcaatc ttatttttta aagtttttaa gttattattt taatggtata ttcacgagta
    16501 cagaactggc tgatcttgaa tttatttctt tgagtaaagt atatacaatc aaaaaaatcg
    16561 tattggattt ttttaaagaa aatgattatt tgaaaaataa agaaatcatt atcccagaat
    16621 ttgactcgcg gaacatcttg ctagctttag tacgttatgt caattgggaa ggctatgaaa
    16681 ataaaaatcc gtatgtagaa gaagcttgta acgagttgat tgattatgta gagactcatt
    16741 tttttaaaag aagatattcg gaagatgaaa agtcctttat catacgagaa atagagatcg
    16801 caatcggaag aaaggcattt ccccttggac tgaaagaaga agataagaaa agcgcagaaa
    16861 cgaagccgtt atttcaatta gtctgtcaag gattggaaga gcaaaaagga attctagact
    16921 tacaagaaga agatgtctat tatatttttt ctttgttcaa cagtagaaat tataccaatg
    16981 agaacatgga gctgttaaga aaagatttcg aagttgttta taaaaatttt gttctcaatg
    17041 acctatcact gaatgaattg attttacaga ttattagtat cgctgaaatc gacgatgcag
    17101 aaaattttat tttcaagcaa tcctttttac aatttgtccg tacgttgtgg gcagatggac
    17161 aagtattttt accggaaagg atctatcttc tatcagaaaa agaacaactt ctgtacggaa
    17221 aaattgtaga aatattggaa gagtggaaaa agaaaaatca aatccaacta agatggaatg
    17281 aaaatttcat tcgaaaattc gtcaaaagtc tttctttgat caacagtgaa caagcgggga
    17341 gacaggaaat agaaattttt gttgtttcag aaagttcagt caaacaattt ttttatcgaa
    17401 cccaatttca tttgtatgcg gaagaaggca tcgctgaaat aaatcctatt ttatttcgtt
    17461 cattagaaga attgcctgat gaatgtctat gtgcgaaaaa aagagtggtt ttgtgcgatg
    17521 ctgctagcta tcaaaatgga ttagaaactg aaaagacaaa gatctatcca atctcattaa
    17581 aaggtgcaaa catccatttg tatcatattg ctcaggaact tcacctatta aaaaaacata
    17641 tttcttgatg agaccttaat taggagacct tctacaaagc tttttaattg tctgtagaag
    17701 gtttttattt gagtcctgat tcgtgcgaag atctacttat ataacaagct ttctctgaaa
    17761 tttttttaaa atgctattga cttagagtca actctaagta gtagaataga taaagtgtaa
    17821 caaatctatt ttcattaaaa gaagatagta cggaggagag aatgtattat gagtacagta
    17881 ttacatgtat tggatgcaat caatagcccc gcagatgtca aaaaattatc tgttgaggaa
    17941 atgaaacagt tggcagaaga gatgcgccaa aaaatcttgc aaaaggacag cgatgtaggt
    18001 gggcacgttg gtccgaatct aggtgtagta gaattaacga ttgcgtttca ttatgtattt
    18061 gattcaccaa aggataaaat cgtttgggat gtttcccatc agtcttatgg tcataagctt
    18121 ttaactggtc gaaaaaatgg ttttgaaaaa ggacattacc gtgaagtgag cggatattcc
    18181 aaccaacatg aaagtaaaca tgactatttt acagtggggc acacatctac atctatcagc
    18241 ttagcaacag gtttagctaa agcgagagat ctgaagaaag aatcaggaaa tgtggtagca
    18301 tttatcggtg acggctccct aagtggtggc ttagcttttg aaggattgaa caatggtggt
    18361 gttttacaat ccaatctaat cgtattagta aacgataatg agatgtctat tgatgagaat
    18421 catggcagtt tatataaaaa cttagctgag cttcgtcaaa ccaacggtaa aagcagcaat
    18481 aacctattta aagcaatggg atttgattat cgttacgtgg ataatggaaa cgatctggaa
    18541 acggtgatcc gtttatttga agaagtaaaa gatattgatc atccgattgt acttcacgtc
    18601 catacggaaa aaggtcgcgg ttatcagccg gcaatcgata ataaaatgaa atatcattgg
    18661 catgtaccat ttgatctgtc caccggggag gcaaagcaag taacttctgg agaaacattt
    18721 aatatgatca tcatggatta tttggataag aaaatgcaaa caagtacagc tcctattgcc
    18781 gcagtcaatg cagcgatacc aggcgccttt ggactgaaaa cattccaaga aaaacatcca
    18841 gatcattatt ttgacgtggg gatcgctgaa cagcactcta tcactttcgc ttctgctttg
    18901 gcttctcagg gagtacgtcc agtcgtcttc caatcaagta ctttcttgca acgggcatat
    18961 gatcaattat cacatgattt agcgatcaac gagaatccag tgattatttt agtcggtggc
    19021 ggaacgatct cagctagtga ccgaacacac caaggaacat ttgacattcc ttacttatca
    19081 agtatcccga acatcaaata tcttgctcca gcaacaaaag aggatatgat ctctatgcta
    19141 gattgggcgt tcgaacaaac agcgcagcct gtagcaatcc gaattcctac acatggtgta
    19201 gaacatggta cagctatcgc aaatgattat agtattccag cctatcaaac agtaaataat
    19261 ggaggaaaag tagcaatttt agctttaggc ggttttcttg aattaggaaa agaaacagta
    19321 aaagctttta gaaaaaaagg aatcgaagca acgttgatca atccaggaac gatcacagaa
    19381 aatgacgtag aaacattaga taaattaaaa gaaacacacg aattagtcat cacattagaa
    19441 gatggtagtt tgtcaggagg atttggcgaa aatatcagtc gttattatgg tgattcttca
    19501 atgaacgtat taaattttgg tgcagagaaa gaattcacgg atagcgttcc tgtagggcag
    19561 ctttatgaac gttatcattt aacaccaaaa caaatcgttg aagatagtct gcgtgtcttg
    19621 aatattcaat aattcattat gctcaccatc cagataattg tttatactag tatctggatg
    19681 gttttttcat tataaaaagc aaaggggtgg atgttatgta tcagcaagta gaagaatatg
    19741 tcaaaaagtt ccaagaaaaa tatcctagtt atcaatcaga aaaattaggt ttcttttcat
    19801 ttggggatac agaaaaaatg gcagacgagt tgagcgaact agttgtaaaa aagataaaga
    19861 ctggtacatc aagtggttac gatctgtata aacaagagaa tgagccttta ccaaaagttg
    19921 gtcaattaga cgtggtcctg aatggaaaaa atgaaccagt ttgtatcatc aaaaatataa
    19981 atgtgaccat cttgcctttt agtgaagtca cgaaagagca tgcttggaaa gaaggagaag
    20041 gggatcggac attagcttat tggcggaaag tccatgctga gttttttaaa catgcttata
    20101 aagaagcgtt gaacatagaa tttacagaag agaagctggt cgtatacgaa gaatttgaag
    20161 taattttctt ttagtaagaa aggtctgctg aaagaaatag ctcattattg tctcctgaat
    20221 agaaaagggt tacattttta tatgaagctg tatttttata taacattact ggaggagata
    20281 ttgtggatac actggaacaa atcaaaggcg gagtcgtcgt ttcttgtcaa gctttggaaa
    20341 acgagccgct acacagttct tttattatgg ggagaatggc tttggctgca aaagaaggcg
    20401 gagcagttgg tattcgagca aatacgacag aagatatcaa tgaaatcaag cgaatcgttg
    20461 atttaccggt aatagggatt atcaaaagag attacgatgg gtcagaagtg tttattactg
    20521 cgacagaaaa agaagtggaa gaacttttgg agacgcaagc agaaatcatt gcactggatg
    20581 caacttctcg taaacgtccg acagaaaaaa caactgctga acttgtccaa atgattcacg
    20641 aacacggtcg gttagctatg gcagatattt cgacttttga ggaagcgctt caagcgcaag
    20701 aagatggttt tgatcttttg tctacgactt tagcaggcta tacagaatat tcacgaaaga
    20761 cgcagacacc tgattttgat ttattgaatc aaatcataga acaagtcgat atcccagtaa
    20821 ttatggaagg acatactgac tctcctgaac aagtagagaa agcatatgaa ttaggtgctt
    20881 tttcagtcgt agttggatct attatcaccc gtccgcaatt gatcactaaa agatatgtcg
    20941 aagccgcaag taaagcaaat aactaaaaaa cacgcacggc acagattctt gacaaaaaag
    21001 aaaaattgat agatagttta aagcagattc taagaagatg aaaaaagcat tacttttcat
    21061 tttgtcttca agatctgctt tttaacgaat tttatagaaa gaaggcgaaa ccatgtttga
    21121 acggagtcct tcagaattga cagaacgtga aaattacaag ttgctgattg gttcagtcat
    21181 ccctagacca gtagcagtag taacgactaa atcagcaaaa gatatagtga atatcgcacc
    21241 cttcagttac ttcaatatcg tcagttcgaa tcgacccatc ttatccttgg cgatccagag
    21301 aaaacaagat gcagtaaaag acacagcaaa gaatattctt gagacaagag aagctgttat
    21361 ccatatcctt gatgaggaca acgtagaaga agtaaataaa acagcagcca atctgcctaa
    21421 tgaggaaagc gaactgtacc tgactgactt gactttaact gattcagtaa tcatttcagt
    21481 accagcattg acagaagcaa aagttcgttt tgaaacatcc ttatatgaac atgtcgagat
    21541 acggaataaa aataaagtaa cagctgattt atttttgcta gaagtacaga aatatcattt
    21601 aaatgaaaca gtctatgatg ataagacagg aaggatcgat ccaagaaaat tgaatgctgt
    21661 aagccgtttg gcaggaaatg attatgcagc aataggagaa attttcacga ttgcacgtcc
    21721 cgaataaaaa ggagcactag ttatgttaaa aataagctat aaaccatcga cagattcaaa
    21781 agaaatgaaa aaagaatatg aaacagtgaa tgattttctg caagggcagt acttagaagt
    21841 tccgccattg caagaccatt ttgtcgttac tactgttact ttagatggta aggaaataga
    21901 aatgccagat caaacgatta gcggattgtt taattacttt aacaaataaa tatttattcc
    21961 gaaaagtgaa aaaacatata aaaaaacaca taaaactaaa aaattatcaa agaatcctgg
    22021 tgcaactgaa agaatttgca acgggattct ttcaacttat ttgttatttt tttctaaaaa
    22081 atattaaaga ttgttaaatt tcactatttc atttcaaatt ccattgccta atcattagga
    22141 aaagtctata atgaactcgt aaatagaata tagtaataac cttgttaggt gaggctccta
    22201 tacaaacata ggctgttgcc cagaaacgtc gaaagtcgcc aatgggtaaa acagaaactg
    22261 ttggattaag gctttttcca atagctaaga atgttttctt tacgttgtat agtgctaaaa
    22321 ctcggacgat gagatgatgc taggtcagaa ttcttgttcg aaaaggtttc tgaccttttc
    22381 tttatatttt tgtgactgac ttatttgatg agacaaactc gctcctcacc tgacaagtgg
    22441 attgctgtgt gaggaggaga tgcggtgaaa aaagatcgat tggtggattt tgggtcctta
    22501 tttgactttg tccatgatcg gtcttttaga agtatacagt gccagttctt atcgtttatt
    22561 gcaagccgat gaaaatacaa aaagtctatt attgcgtcaa ctaattttca tatttttgag
    22621 ttggagcgtg atcttcttag ctcgttcagt caaactacac tatttacttc accctaaaat
    22681 agcaggatac ggtttagcct tatcgatttt ctttttagta ttagtaagaa tagggatatt
    22741 cggtgtcact gtcaacggcg cacaacgttg gatctctctg tttggcattc aattccagcc
    22801 ttctgaactg gcaaatcttt ttttgatttt ttatttaagc tggttttttc gtgacggaaa
    22861 tagtagccca aaagatctaa aaaaaccatt cctgattaca gtaggtataa cttttctgat
    22921 tttatttcag ccaaagattg ctggagcatt gatgatcctt tcgattgcgt gggtcatatt
    22981 ttgggcagcg gcggttccat ttaaaaaagg gatctatcta atcgttactt tttctgcatt
    23041 gctgattgga gcagcaggcg gggtattata tttaggaaat aaaggttggc ttccacagat
    23101 gtttaatcat gcttatgaaa ggatcgcgac tttaagagat tcttttatcg atagtcatgg
    23161 tgcgggctat caaatgaccc attcgtttta tgcactatat aatggtggca tatttgggcg
    23221 gggattagga aatagtatca caaaaaaagg gtatcttcca gagacagaaa cagattttat
    23281 tttttcgatt attacagaag agcttgggct aatcggtgca ttgtgtgtgc ttttcttatt
    23341 gttctcatta tgcatgagaa tcttttgttt aagcagtcgc tgtaaaaatc agcaagctgg
    23401 attgtttctt ttaggattcg gaactttgct attcgttcag acgataatga acgtgggaag
    23461 tatcgcgggg ctgatgccaa tgactggtgt gccattgcca tttgttagct acggaggaac
    23521 aagttatctg atcctttctt taggaatcgg aatcacgttg aatatttctt caaagataca
    23581 ggccgaagag ttggcgctct atcgacctga aaaacaataa agagaaactg agaaactctc
    23641 agtttgaatt atcataaagt acaatctttt atttttcaag cgagaggttc ttttagaaag
    23701 aggaattcgc aatgaaagta tctcaaaaaa tcatattatc tattttgtta ctgcttacat
    23761 tagtagttgg ctatttttcg attgagttta tccatggatt ttcgtctgca aaacagagtt
    23821 caactgtgaa aaaggtagag ccgaaaagta tccctaccac actaaatgtg gctttgattg
    23881 gttcagatgc tcgttcgaaa gacgaaaacg gtcgctcgga ttcacttctg gttgcacaat
    23941 acaaccagaa aacacaacaa gcaaaactga tctctatcat gagagattca tatgtcgata
    24001 ttccaggtta cggaatgaat aagataaatg cagcttactc ttatggggga gttgatttat
    24061 taaatcaaac attaaaggaa aatttcaaat ttgaagctcc ctattatgca agtatcacat
    24121 ttcaagattt tatcgattgc gttaatgaac tgtttcctgg tggagtcaag atcgatgcag
    24181 aaaaatctct agatttagat ggcgtatata taaacaaagg agagcaagtg atggatggta
    24241 atactttact ccagtatgct cgatttcggg aagacaaaga aggagacttc gggaggatca
    24301 gaaggcagca gcaagtgatc aaagctatct ctcagcagct gaaagacgta acttcaatat
    24361 tcaagctacc caaagcggtt gggaaattac ttggtagtat ccaaacgaac cttccagaaa
    24421 gtgtgcttct ggattgtggt atggatttcc tcaaagacat atgttagaat aaacaggtat
    24481 aaatagtgaa ataaaggaat gacaagcaag agaaggagga aaaaatgaaa agaagtgaca
    24541 agcacggcaa aaatcgaaca ggcgcttata ttgccggcgc agtgatctta atagcagctg
    24601 cgggtggcgg ttatttttac taccagcact atcaagaaac ccaagcagta gaagctggag
    24661 aaaagacagt tgagcaattt gtccaagctt tgaacaaggg agattataac aaagctgcag
    24721 aaatgacatc aaaaaaggcg gcaaataaaa gtgcattatc tgaaaaagag atcttagata
    24781 aataccagaa tatatacggt gctgctgatg tcaaaggact tcagatatcg aatctaaaag
    24841 tagataaaaa agacgattct acttacagtt tttcatataa agcaaagatg aatacctcat
    24901 taggtgaatt gaaagatctt tcttataaag gaacattaga cagaaatgat ggtcaaacca
    24961 cgatcaactg gcaacccaac ttggtttttc cagaaatgga aggaaatgac aaagtaagcc
    25021 tgaccacaca agaagcagca agagggaata ttatagatcg aaatggtgaa ccattagcaa
    25081 caacaggcaa actaaaacaa ttaggagtcg ttccaagtaa acttggagat ggaggcgaaa
    25141 aaacagccaa tatcaaagcg attgcttcct ccttcgactt aacagaagat gctatcaatc
    25201 aggcgatttc acaaagctgg gtacaacccg attactttgt cccattgaaa atcattgatg
    25261 gagcaacgcc agaacttcca gctggagcta ccattcaaga agtagacggc agatattatc
    25321 ctttgggtga agcagctgct cagctgattg gttacgtggg agatatcaca gcagaagata
    25381 ttgataagaa tccagaatta agcagtaatg gaaaaatcgg tcgctcaggt ttggagatgg
    25441 cttttgataa ggatcttcgt gggacaacag gtgggaaatt aagcattaca gatgcagacg
    25501 gtgtagagaa aaaagttctg atcgaacatg aagttcaaaa tggcaaagat atcaaattga
    25561 caatcgatgc gaaggcacaa aaaacagctt ttgacagtct aggaggaaaa gctggatcaa
    25621 ctgttgcgac aacgccaaaa accggtgatc ttcttgcgct tgctagctct ccaagctatg
    25681 atccaaacaa aatgacaaac gggatctcac aagaagatta caaagcttat gaagaaaatc
    25741 ctgaacatcc attcatcagc cgatttgcga caggttatgc tcctggatct acgtttaaaa
    25801 tgattacagc agcaatcggt ctcgacaacg gcactatcga tccaaatgaa gtgttgacga
    25861 tcaacgggct taaatggcaa aaagacagtt cttggggatc ttatcaagca acgcgtgtca
    25921 gtagtgatgt atcacaagta gacttaaaaa ctgctttgat ctattccgat aatatatatg
    25981 cggcacaaga aacgttgaaa atgggtgaga aaaaatttcg tacaggctta gataaattca
    26041 tttttggtga agaccttgat ttgccaatta gtatgaatcc agcacaaatt tctaatgaag
    26101 atagctttaa ctcagatatc ttgctagctg atactggata tggacagggc gaacttctaa
    26161 ttactcctat ccagcaagca gcaatgtatt ctgtttttac caacaatggc acacttgtct
    26221 atcctaaatt gattgcagat aaagagacaa aagataagaa gaatgtcatc agcgaaacag
    26281 cagtacaaac gatcgtgcca gatctgagag aagttgtgca agatgtaaat ggtacagcac
    26341 attctctttc tgctttaggg attccgttgg cagcgaaaac tggtacagcg gaaatcaaag
    26401 aaaaacagga tgtaaagggg caagagaaca gtttcttgtt tgctttcaat cttgataacc
    26461 aaggttatat gatggtcagc atgttggaaa ataaagaaga tgatgattca gcaaccaaac
    26521 gagcatcgga actattgcaa tacctcaacc aaaattatca ataaaaaatt gctttttaag
    26581 tacagtaaaa ggactgtggc gttatcgtca cagtcctttt ttcaaataaa cggttttcac
    26641 gatgtctctt tcacaacttc tttttgattt actcacactt cataaacttt ttttgtaaaa
    26701 tatttgagaa caagtggaga aataagtgta cttaataaaa tcacgataac taaaggtgaa
    26761 tagtactgtg gttcgatcaa ttgactttgc tgtccaattt gtaaaatgat caaagccatt
    26821 tctccacgcg aaatcatacc agcaccgacc atcaatgaac tatgttgaga aaaaccggca
    26881 atctgagcac caaaataacc tccaagcaat ttggtcaaaa tcgctacaag cgtcaatata
    26941 gaaataaaga gtagttgttc actaaagtca gaaaaatcaa cttctaatcc tacactgaca
    27001 aaaaatactg gtataaatac tgcatatcct aaagcctcta cattgtggta tacttcttct
    27061 ttaacctttg tctgactgac agctatccca gcaaaaaaag caccaatgac agagctaagc
    27121 ccaacaagat ccgctacgta agacattcct aaacaaataa ctagcgatac gatgataata
    27181 gaagaatttg cgtacacttt ttctgcaaat gaaagtagga aaggcgcaat ccatttgact
    27241 aataagaaaa taaaaacaaa ataaattagc tgttcaatca aaacaagcgg taaagaagca
    27301 ttgctagaag cttcccccgt tagaaaagat aggctgaaac ttagaactaa aacgactaaa
    27361 atgtcatcta ccacagaagc acccaaaatt gttgatcctt cttttgtatt cactacgttt
    27421 agttctttta atacttctac tgaaatactg acagaagttg ccgcaagaat aatcccaaag
    27481 aaaatcgctt catttcccga aacttggaat gctttgcctg tcaaccagcc aaaaacaacc
    27541 gggaagatga tcccaagcaa agcaacgaac ataccaggtc ggaaatattt tttcaaaaga
    27601 gataaatcac tttccagacc agctaaaaac attaataaga tcacaccaat ctccgaaaag
    27661 tcatggacta gaatatcagg tttgacccaa ttcaatccag cttggcctag caaaacacca
    27721 acaagtaatt gtccaatcac tgctgggata cctaatctcc gcgagatatg tgagccaatc
    27781 gttgttgaaa tcaatatcag gcataaaata ccaataaatt ccattctcat cattcctttg
    27841 tataaaatat agcccgaact tagcataaca tacattattg aaaaaatagg aaaatatact
    27901 cacaaaaaaa ccaacaatcc aaaagatttt tttggattgt tggtttttat acggtctatt
    27961 ttaataacta aaaatgatta acgtatagtc atttttctta ttctgatgaa attgataatc
    28021 tcctggatgc ccatgaaaat caaaataaag ccgaatattt ggaatagaag catcaaactt
    28081 ttgaatggat tgaacaataa gacgaatccg ccaatcaaca acagaatact actataaaca
    28141 ctccaacttt tagcttttgt attcatgctg aagaacaact ggaacaagct gttgatgata
    28201 acagctaatc caagaagaat cggcaggata gaaacgattg caggtgcaaa agcatagacg
    28261 atcagagcta agatcaggaa aaaaagacca ctgaacagac cgatactcca agaacctgtt
    28321 ttccttttaa aacggtaagc ctcaaaaaga ttcaacaacc caagcaaaac aagataggcg
    28381 gtgatcagat aaccgataaa atgaaaaaca gcagaagggt ttagcacaat cgcaatccca
    28441 gaaataatat aaacagcagc tcttaataag gcgtattttt gaatattttg tttaatcgtc
    28501 tcaaacatat aagaaaacct cctttgactt attttaacgt gaactagtca ttttaccaaa
    28561 ttaaatgtta caaaatgagc gaaggagaag aatatctctg gaaaaatcaa cttctgagga
    28621 tcttttccat ttttttgcct tttgctagct catcgatcat tttatctaaa taacgaattt
    28681 ctttcatcaa gttatcctcg atgtcttcta ctcgtacacc acaaacaaca cctgtaatca
    28741 aggaacgtga aggattgggg acaggggctt ccgcaaaaaa ttgttcgaaa gtcacttgtt
    28801 tttgtagttg atattctagt tctgtttggg aataacccgt cagccaacaa atgatttcat
    28861 ctacttcctc ttttatacga tcttttctct ccgcttttgc tacatacata ggataaacgc
    28921 ttgcaaaact tgtcgtaaaa atacgatttt gcgccataat cagtcacctt tctttttttc
    28981 aaattattta ctacttatag tatataagaa aaagagaaga aaaagcgatt attcaaaaaa
    29041 acaaaaagga ttgtgacaaa attcttgtca ccatcctttt ttccgctctc tgacttttta
    29101 caatcttcat agctcaagtg cgcatcagat aatcgaatgc tcctaaagct gcagtagctc
    29161 ctgaacccat tgaaacaatg atttgtttgt atggactatc tgtacaatca ccagctgcga
    29221 aaacgccggg gatattcgtt gcgccatttt tctcggtcac tatttcattt cttggattca
    29281 tttcgatcgt tccatctagc caatccgtat tagggagtaa gccgactaga atgaatactc
    29341 ctgaaacagc tagtgtatgc atctccatcg tacggcgatc gatataggag agagattcta
    29401 cctgattcgt accgctgatt tctttcgtcg ctgcatgttt gataacagtg acattcgcaa
    29461 gagagactag tttatcctgt aagatttgat ctgcttttaa ttctggtaag aattctagaa
    29521 catatacatg ttttgctaac ccagccaaat cgattgctgc ttcaacacca gaattaccac
    29581 caccgataac agcaatctct tttcctttaa ataaagggcc gtcacagtgt gggcaataag
    29641 caattccttt atttttaaac tctttttcgc ctggtacatt gatagaacgc cagtgcgcac
    29701 ctgtcgcgat gatggcggtt tttgctttaa gtgatatacc gttagctaag ccaatattaa
    29761 taaaatgttg ctctttattt aaggaaacgg cctgttgatt catcataatg tcgatagggt
    29821 aactacgcac atgactttct acttgctgca tcaattttgg accttctgtg taagaggtac
    29881 caatcatatt ttcaatccct agtgtttcaa cgacttgtcc gccgaaagaa tcagcgacaa
    29941 gtcctgtacg gattccttta cgtgctgcat agatagctgc actactagct gctggtccac
    30001 cgccaatcac taatacatca taaggttctt tttcaaacaa ctcttcttca atcaaagggc
    30061 cagtgatttt ttcaacaatt tgttcgatcg tcatgcgtcc gctactaaat tcttctccat
    30121 ttaaaaacac agttggcact gccatgattt ttttatcatc gatttctttt tggaacatcc
    30181 caccttcaat catcgtatga gtaatatttg gatttaatac agctaatata ttcaatgcct
    30241 gtacaacgtc ggggcaatta tgacaagtca agctaacata actgtcaaaa tgcaatgttt
    30301 gtgttatttt tttgatttta agactcaaag attcactgat tttcggtgcc cgtccactaa
    30361 tttgtaacat agccagtaaa aaagaggaaa attcatgacc gagggggata ccagcaaaaa
    30421 cgattccact ttctttgcca actggattga tagaaaaact aggtgtgcgc atcgaatctc
    30481 ttttttccca agagatttta ggagacattt ctgctatttc cttcgtaaat tcagctagtt
    30541 tttgactatt ttcactatta tccaaactaa cagaaaaaac aataggagat tcaatcagtg
    30601 ctaaatattg ttcgagattt tgtttagttt ctttgtctaa catatccacc acctaaatct
    30661 ttccaacaag atcaaaactt ggtttcaatg tttcgccact ttctttccat tttgccggac
    30721 aaacttcacc tgggtgggta cgtacatatt gagcagcgcg aatcttatca atcagtgcac
    30781 tagcgtcacg accgattcca tctgcattga tttccatagc ttgaacgatt ccgtctggat
    30841 caataataaa tgttcctcgc tgagctaatc cttgctcttc atccaaaaca tcaaaaatac
    30901 gagaaatctg atgagacgga tcaccgatca tcacgtattc gattttaccg atagcatctg
    30961 atgtatcatg ccatgctttg tgagtaaagt gggtatcggt agagcaagaa aagacttcaa
    31021 cacctaaaga tttcaatgta ctgtattgtt cttgtaagtc ttctaattca gtaggacaaa
    31081 caaaagtaaa atcagctgga tagaagcaaa gaatactcca gttccccata agatcttttt
    31141 cactgacttc taaaaattct ccttgatgat aagcatgtgc attaaattct tcgatttttt
    31201 tcccaatcaa tgacatagta aaacctccaa taataattat ttatttataa ttattgtaat
    31261 ttagttggag ttgcaaagtc aatggatatt ttgttattta ataaagatta ctcaaaaacg
    31321 aaggttaatt ataaaaatag aagaggtcgc aagaaaatgc tactgctgga aatactcggg
    31381 ataacgttga gtaacagttt cctgttcttt cagcatcatg tgtaagtgca atcccgtttg
    31441 aaatcgagct tcttctggtt ttttatcaac taaagccttg agtaaatcat aatgttgttc
    31501 catgatcgtt tcccatggaa gcccctgaat ggtcactcgt aaccagcgga aacgttctaa
    31561 atgggtatta tggtcatcta accagttcca aacttctttt cttcctgcaa tttcgaaaca
    31621 agcttcatga aataaattat ctgcacggaa aaaagcgcgt tcgtcattta ttttgactgc
    31681 tttttcttgt tcttctaaaa tcgtttctag cactattcgt gtttgtgtgt ccaatttgga
    31741 acaacattca atcatgattt gctcttccaa ctgttctcgg acaaagcgag cattttctgc
    31801 agaaacaaga ttaattttgg aaacatacgt accactttga ggtatcgtat acacgagttc
    31861 ttgctgacgt agttgaatca atgcttcgcg aatgggagtc cggccgatag caagatgttc
    31921 ctccagtgcc ttttcagata ttttccttcc aggttctaag tcagcataga taatttgttt
    31981 acgaatcgct tgataagctt gtgattgcaa gctgcttttc atctttattc ctccaaaatc
    32041 atttctatga acgtagtata acagaagagg tctgaaaaac aatctggtat gtcacattaa
    32101 ctagtaaatt tgtataaata gtaaaatttt ggttgacata gcgattttta ttgcataaaa
    32161 ttcacttgaa tacaaaaact aatatgttag tttaggaggg gaaaaatgat tgatttaaac
    32221 aactggagga actttatccc tgaattatct caaaaagaag tagaaatacc tcattttgac
    32281 cgtgcatcat taagagaaaa tggacaaaaa aatcctgtct ggatccattt cggtggcgga
    32341 aatctttatc gaggatttca tgcagaaatc gctcaacgtt tagcggatct aggcgaattg
    32401 tccactggtg tcattgtttg tgaaacattc gatgaagaaa taattgaaag ggcttaccaa
    32461 gattttgatg atttgattct tgaagtggtc atgccaagca gtggagagtt cgtcaaacgt
    32521 atattagctg cgacagctga cagtctgtat tgtcatccag attgttctga acactttgat
    32581 aagatgattc gacactttga aaatcctagt ttacaattag ttacttttgc tattactgaa
    32641 aaaggttatc gattgaaaga tacaaataat aaatatatag gaccgattgc agtcgatata
    32701 aaaaatggtc caaagaagcc atcacataca atgagtattc ttgctgtgct actttataaa
    32761 cgttttttat ctggagcttg gccgattgca cttgtctcta cagataattt ttcacaaaac
    32821 ggtagtcaat tacgtacttc tttgctaacg atcgcaaaag aatggcaaaa ggaaggttat
    32881 gtacaaaata catttatcca atacttatcg aatgaagaaa ttgttgcgtt tccatggacg
    32941 atgattgatc gtatcacccc gaatccttcc ttgtcagtta gcaaaatgtt ggcaaaagag
    33001 ggcttttcaa atatgtcgat tttccaaacc gcaaaaggaa ataatattgc tccatttgtc
    33061 aatacagagg acatccatta tttaatcatg gaagatcatt ttcccaatgg acgtccgaaa
    33121 ttcgaaaaag ctggggtatt cttgactgat cgtgcaacgg tagataaagc agatacgatg
    33181 aaggtgacga cttgccttaa tcctttgcat acgtctttag ctattatggg ttgtttactg
    33241 gggtatagga gcatagctga ggagatgaaa gatccagatt tatcgctgct agtttctgaa
    33301 atcgggtaca atgaaggcct cccagttgtg gagtctccag gtatcattga tccaaagatc
    33361 tttctggaag aagtaattac tgtgcgcttt tctaatccaa atattcctaa tatgcctcag
    33421 cgaatcgcca cggatacctc tcaaaaggtg gcgattcgtt atggtgagac gattaaaaaa
    33481 tatatggaaa tagaagttaa agacccgcag acacttgtat tcataccatt gactctcgct
    33541 gcttggcttc gataccttat tggcattgat gatcaaggaa aaccattcat cccgagtcca
    33601 gacccactat tgacagacct tcagcataag ctttccgata ttcaactggg tacgcaagat
    33661 acatcacata ttcatgagaa aatggctcct attttgtcaa ataaagaaat ttttggtgta
    33721 gatctttacc aagcagagct tggcagaaaa atagaagaaa tgttcatcaa gatggtagca
    33781 ggaccaaatg ccgtacgaaa aacattacag gattacttac aagaacatgg aggaaattta
    33841 tcatggaaat gacttttaga tggtacggat cacaggaaga aaagattacc ttagatgaaa
    33901 tcagacagat tcctgcggtc aaagggattg taggcacatt gatggatata ccagtaggag
    33961 aggtatggcc tagggagagg atcaaagaac taaaagaaga aattgagtct cgtgggttaa
    34021 cactaaaagt aattgaaagc gtcaatgtgc atgatgccat taaaattgga ttaccttccc
    34081 gtgagcagta tatcgaaaac tataagcaga caatccgaaa cttggcagaa tatggaatag
    34141 aagtcatctg ctataatttt atgcctgtat ttgactgggt gaaatctgac cttgactacc
    34201 gcttagaaga cggctcatcc acgttagctt ttatatctga tgatattcca gatgatccaa
    34261 gagaaatcgt cgcgcgcatc gaacattcca gcaatgaatt tggattgccg ggatgggaac
    34321 ctgagcgctt agctcctatc aaatccttgc ttgaagccta tgcatcagta gacgaagaaa
    34381 aacttcgaga aaattttgcc tattttctcc aatcaatcat cccaacatgt gaagaggtag
    34441 gggtcaaaat ggctgtacat ccagatgatc cgccatactc gatttttgga ttagctcgaa
    34501 tcgtaaagaa tcgagaagat ttagattggt tgtgtcgcat agtagacagc ccttataacg
    34561 gaatcactct ttgtacaggg agtattgcag aagatccaga aaatgatgta tatgggattt
    34621 tagcagaatt ttgccaaaga gatcgaatcc catttgcaca tgttcgaaat attaaatttt
    34681 tagctaatcg agatttctat gaggcaccac ataaatccga atacggttca ttagacatgt
    34741 accgcatact aaaaacaatg tatgacaacg gatttaacgg atacatccgt cctgatcatg
    34801 gaagaatgat ctggaatgag acaggaagac caggatacgg cttatatgat cgagcattag
    34861 gtgctgttta tctaaatgga ttatgggaag caatcgaaaa aggaaacaaa agtaaagata
    34921 attagtgaaa aaaactgtaa ttttattatg taaataagaa ggatgttcaa attcttgata
    34981 cataaatccg gaggttgtta ataagcattc ggatttatgt atcttatttg gtctaggaag
    35041 taacttgatt ttcttttttc gattgatcca tgagtgcttc ttcttttaat tcaaagatat
    35101 attctgagat cctcataatc acttttttcc agtcttctgg tgtgatgatt ccttttaaaa
    35161 tatagatttt tttgatatga gaaggcaatt gtttcaaagg gcagtcgctg ataacgatgt
    35221 tgcagttctc cataaaatca ttttgtattt tgatcgattc atttgaaaaa atttgttcta
    35281 tcttaacgat cagatcttta ctgatataaa aatcacgcgt atagttcaca ccaatcacaa
    35341 ttcgcggctg ttttttgtag cgatcataca aatgtactag gtcttcaacc atccattgca
    35401 cattttcctt ttctaaaata actggtaaca agtgttgatt ttgttctctg aaatccatat
    35461 aaaattgttc aatggcggtt tggacttctt tcaatacgct atgttcttga taaagcatga
    35521 aagtaggaag gggcgtattt ggttgattga agttaagaaa tccattataa agtttatttc
    35581 gtgcgaatgc caatgagtaa agaatctttt ctttttcagg tataaacaaa tcaaatacag
    35641 tacaaaggga ctccaccatt tctcttgaat aaagaacatg aggaacgttt gcttttttta
    35701 aaagtttgta ttgctccaag cttgtttctt ccgattcgat tttcgtgata gaaagtcgag
    35761 ctaaaatatt cactaagatg cgttgttcgc gacaaattgg cagattaggt cgcaaaatat
    35821 ctacagagag atcaataaaa aagtcaatat attcatactc tgtgaattct ttttgtacgt
    35881 ctttcacaga agttgcagga aaattctctt tacatatttt taatagaaaa tataatttat
    35941 ctatcatacc gctatttagt cggtcaagta cttctttttt aaaaaaagta ttcatcataa
    36001 aagccactac ttgcggatct tcatcataaa attctgtagc agtacttgaa aagatgttcc
    36061 aataaatatc taatgctgca tattgaattt gtacctcttt tccagaaaaa gactttctgc
    36121 cattattaga aaaggagata gacaaaccgt actatgctaa aaatgcatta atctttttca
    36181 ttttcgtata caaataagag gcactatagt ttgtttgctg actgaaactg ataatcgaat
    36241 ttgtctgaca gctgaacaaa gaagtcaaga tctgataact gactgattcg ttgcagtatc
    36301 ttccaaatag acgataatag cagtaagccg gatcaattcc ttcaaaattc aactttaaaa
    36361 aaggtttttg cttatcaata tgcagttctg ttagattgag acgctcaaag tcttgttcta
    36421 attctttgat gtatagtaaa aaatttgatt cagacatatg gaaatgatct gctaaatatt
    36481 gtgtagtaat aaagaaacga tgttcagata ggaaaagaaa aatatctaat tttgtattgc
    36541 tttttttctt caagataaac gttttaatcg cttcttgagt ttgcatgaaa gaggctcctt
    36601 tttacttaaa ttgttaaaac ttgaaaatat tactgttttt ttcataaatt tagacaaaaa
    36661 aacagtaaac atataggtag aatctctact atcttatttc ttgcatacaa aaaaatcaag
    36721 gagtgagaga gttatgagat attcaaccat cttaatatca acatttgcag ccttaagctt
    36781 atcgcttact ataaatcaga cagtccacac agaggagaca gaaacagcca aatggacaga
    36841 aaccaagtgg gccaacgtca atcgaattac ctttcaggat gaattttcat ccttcaattc
    36901 aggagtcgca aaattaagaa aaggacaaac agcgaccatc aaagcaaaaa ttgactattc
    36961 gggagactta gcacctatac tacaatcagc tgttacattt gagaatgttg atcccacttt
    37021 gtcgattggc tatgacgaga acactttgac tatccaacac aagcaagcga tatttacctt
    37081 caccgttaca ttaaatcagg acttgttaaa accagcgctt tttactgtca aggtatcaga
    37141 tggactaccg aacgatcatc atttaacgcc gtatagtcag cggcagacaa ttgagcaaga
    37201 ttcagccatc gactcaggag gagatcttgt tgaagaacca acagataaac cagaaaatga
    37261 aaataagcca gaagtaccgc ctacagaaaa tccagacgga gaacagaaac cggaaataga
    37321 acctggagaa gaacccgata cagaaactca accagagcca gacaataaat caaaacctga
    37381 aataacccct ggagaaaaac cagatgtaac tccagaacca gatacggatt ctggaaacca
    37441 aacagtaccg gaaacaaatc cagacacaga taatgaaact gaaaatccag aaaaaccaga
    37501 ggtagatcca gaagaaaaac cagatgtgac tccagaacca gatacggacg caagagacca
    37561 aggaatacca gaaaaaataa acaaaaaaac aattcaagag gatggaaaaa aagagagtaa
    37621 aaaatcaaat ctagcaattc taaaaataaa tgaagagcag ctgaataaaa aatcacgaat
    37681 atttgatagc gcccaatcag ctgaaacctt aaaaagtagc aaggatacaa cctttgctgt
    37741 cctgaaacga aaaataaaca gctaccaaaa tccggagagt cacaaaacaa agttatactg
    37801 tggagcggaa tcattctatt aagtatagca acaatgcttt ctgcaaaaag atttaaacaa
    37861 aacagatctc tctaacattt gaataatgtc tgtgaacgca tttttcaaat aaaaagaaat
    37921 atccagaaaa tgaccccaaa ataccagatt gaaatctgat atttggggtc gttcatactt
    37981 tatctttctt catatttatt ttaagggata tctgtttctt ttggaagatg gttcgggatc
    38041 tttttcactt tcaatacatc taaaaagaag gtaaagatcg gaatgccgac aatcaagccc
    38101 caaacgccaa agaaccgttc gctaacaagt aagaccacaa atgtataaaa aatcggcagt
    38161 tctgttttgc tggacatcaa cttcggattc agcacataag actcaattag atggacaatc
    38221 aaaatcgtaa tcaggatata aacaacatct cggatgcctc cttgggaata agctatgaaa
    38281 gatagaggaa tacaagaaat gataacacct gctactggga tcagacttaa aatgaaaatc
    38341 atgatcgcta aactcagcag ctgatgaaag ccaaatacag ccaaggcgat tgtagtgagc
    38401 aacgtattta aaagagcgac aacaaattga gcttctaata ccaaaccaaa tgtattgaca
    38461 aacttatcgg caaaatagta aatatcttga aagaaccaag aaaattcact ttttaaaaac
    38521 aatcttgaga atacaattgt ttttttcttt tcaatcataa aaaagaaact taagatgaat
    38581 gacatagcaa acgccactgc catttttcct atatcctgta aatagccaag cgcaatcgaa
    38641 gcgccatttt gaagctgttc aaaaaaatcg tttcgctcaa tataagtatg gatatattgt
    38701 aaaacaggat ctgcatcttt tggctgatgc tcgtaaaaat taataacgga ctggatcatg
    38761 tcaaatgttt gatgaataag catcgggata tactttgtga atgccagata gataaggtaa
    38821 acgatcagtg tataaatcat gatagctaaa acacctgtag ggattcggac aaatcgctga
    38881 atgatttgaa caagatgaat catcaaataa gtaaagataa atgtgagcaa aatggttgta
    38941 atcatacttc taactaagaa aagaacaaaa acgacaaata ataaaacagt gagacggcgt
    39001 attttttcat tcgccaaaaa acgctgataa acggtcaaat cgacaacctc caaataacaa
    39061 aaaataaaca cgttattcat tatatgatgg aatatgaaaa taagaaagag caaaaagaaa
    39121 aaccgctaaa tgacgttatc ttatgagttg gttttcctca taaaatcgtt catctagcag
    39181 tttcagccct ttttctggtc ttgatgaaaa ttatctagca tttttcgggt cagatgttgc
    39241 agtgtatcca attcttcctg ttcaagtgga agataagact tgatcttttg tggaatacct
    39301 tctgcttgtt tttgcaacgc agcaccttga gcagtcagcg taacatttac gattctttca
    39361 tcacccgttt cacgctgacg attaatataa tttttttctg ctaacttttt tagtaaggga
    39421 gtcagcgtac cagaatccag acacaaatca tttcctagct ctttcactga agtctttttc
    39481 ttttcccata aaactaacat cacaagatac tgggtatagg taagattcag cggcttgagg
    39541 aggggagtgt agtgtctaat gatttcttta gaggcggcat ataaaggaaa acatacttga
    39601 ttaactaaat atagatcttc catttttcca cctccgctgt tttactatag tgtatcatag
    39661 cggatttaca caaaaaagtc tattcactaa ctgctttcag agtaacttct atatttccag
    39721 ctgtagcttt tgaatacgga cacactttat gcgctgcctc taataattct tgcgtttctt
    39781 ccagagaaag accttcgata gatccttcaa tctctacacc taagacaaag ctcgtttcac
    39841 tttctgaata aagggaaact tgtgcactga cagtagaagc cccagagata tttttttgct
    39901 gtttgatcaa ttctaatgca ctgttaaaac atgcactgaa accagctgca aacaattgtt
    39961 cagggttggt tgcattttcg acgcgtttac caggagctgc aatattcaat tcgaatgtac
    40021 gatcgggatt atgcacttct ccagagcgtc cgcctgtgtt gatcattttc gtagaataca
    40081 tttttttcat aaaattacca cctttaatta tattttatac aattgaattt tacacaatat
    40141 aattgtggaa agcaaagaaa tggattggca taagataaat aagagaaagc acatgaaaca
    40201 gacgcgcttt ctcgaatagc aaacatatac aaaaaatatc agagacaaaa aataatctca
    40261 tcataaacat tacatatatt tctcaaaaag ttgttttctt tcttcaaaaa ttacttcacg
    40321 atggacctga tgaagcatcc ataaataacc aaaaggatct ctgaacattg agttagtcac
    40381 accaaagtcc atcatttctg tcatttcttg aatctctaca cagccatttc gtaatgcttt
    40441 attatgtgtg tcctcgatat cagagacgat gatattgaac cagatcgtat ttggatgttc
    40501 agcagtagga gcagtcaaac caagagacgt gttttcatcc agcatatgga atctcgtacc
    40561 atacaaggta aaaatgactt cattattgcc tctagggtaa tctgttgcct caatcagttg
    40621 tatttcatca aagattgttt gatacagttc tagtgctttc aaactatcat ttaatacaaa
    40681 atcgatttcc gttcctttat gcataaagat ctcctctcct tttcagtcga acagttacta
    40741 gattctttta ttataccagc taaagaaaac gcattcaaaa aaatagcgga tttacttacc
    40801 aactcattcg attggatgat aagtaaatcc gcgtcccatt acttctgcta cgctgctgac
    40861 aatgacaaag gcacttggat cgatttcttc tatcaatggt ttcattcggg aaaattcatg
    40921 atcagtcaca acgatcaata aaacctcttt tgactttcga ttatacccgc cttttgcctc
    40981 tagcagggta aggccacgtc caatctcagc acttaagcga aggcggatgt cttccaaata
    41041 atgttcactc atgaccataa cagatttctt tcgattgata cctgtttcga tataagtcat
    41101 gacaattgaa gtgattgcaa tagataaaat agcataaaga aactcttcta ttccaaaaat
    41161 aaacagatta agagaaacaa cgaatgcgtc tgtaaaaaat aagccaatcg aagtattcaa
    41221 gtggaaatat tttttaaaaa tgaggggagg gatcgtcgta ccgccgctag aagagttgtt
    41281 tttatataaa atcgcaactc ctaaagcaaa aatcgcactt ccaaaaatga cagacaacaa
    41341 ccgatctgaa gtaatcattg tttctggaac tattgcaatg attaaaggaa aaaccaagct
    41401 tccgaaaagt actttaaaaa agggtttttt acctaaaaat agaagagcta gtaccaacat
    41461 aacgatattc aacactaaaa taactatagc tcggtcaaag cctaaagcag cttccagtaa
    41521 tattcctaga ccgctgacac ctccagcagc aatatgatga ggccctaaaa acatattgat
    41581 agcgactcct aatatgaaga gggcaaaaat aatcttaatg tatgtccata taaattgtct
    41641 cgtttctttc atttattcac ttccttaatt cattaataat actcttatct tattataact
    41701 tacttttcac cttaagttaa ctttaattaa taaaaaaatt aggctagtct aaattattat
    41761 gtttcattct tctagaatat acttctacgc caaaaactgt taaaaaactt ttactttaga
    41821 aaattggaga aattgatcgc ttaagataaa ttcaggacac taaatagtac aggaagtaga
    41881 ctaaaacttt taaaagtttt aagtctatct atttggcaag tttaaaaaat aaaaattcgg
    41941 tatcaaaaaa ctgttaccga taacattttt gaaagcgttg tcttttgctt ctctatcact
    42001 tatagtgatg acgtcatatt aaaacacaag gaggaaatca atggatacag ctgcaattta
    42061 tcatcgaccg gaaagtgaat atgcatttct atatacgaat acaagatttc gtattcggct
    42121 tcgtactagg aaaaatgata tcaaaaaagt atatgtgcta tgtggagatc catataccat
    42181 aacaactgaa aaatggtatc aaaaacaacg accaatgaaa aaatgtctaa gtaccaatgt
    42241 tcatgattat tgggaaattg aagtgacgag cgaaacaagt cgcttacagt atgcgttcca
    42301 tgttgttggg gaagataaca cggactgttt ttacggtgat caaggaattt ttccttatcg
    42361 agaaaatgtg attactgaac caaattttta ttttcgaata ccttattttc atcaaatcga
    42421 tcgattcact attccagaat gggtaaaaga aacagtatgg tatcaaattt ttcccgaaag
    42481 atttgcaaac ggggacaaag caaatgaccc cgaacacact ttaccttggg gaagtaaaga
    42541 tccagaccga gaagactttt tcgggggaga tttgcaaggt gtgatggatc atttggatta
    42601 cttgacggac cttggcatca atggcatcta tttttgtccc atatttaaag ccacatccaa
    42661 tcataaatac gatacgattg attattatga ggtggatccc gcttttggcg ataaaaaact
    42721 tttaaaaaac ttgattgatg aagcacataa aagagggata cgtatcatgt tcgatgctgt
    42781 attcaatcat atgggtgtcc attcaccaca gtggcaagac gttctcaaaa acggagaaaa
    42841 atcgatctat aaagactggt tccacatccg ttttttccca gtagattctt atcagatgac
    42901 tgacttacca gaaactgctg aaaatatccc atatgatact tttgctttta ctccattcat
    42961 gccgaaacta aatacagcaa atccagaagt gcaaaaatat ttgctggata tcgcaactta
    43021 ttggataaaa gaattcgata ttgatggatg gcgtcttgat gttgctaatg aagtcgatca
    43081 tcatttttgg aaaaaattca gagaagcagt tacagaaatc aaaccagaca tctatatcct
    43141 tggagagatt tggcattcct ctcaagcttg gctgcaaggg gatgaattcc atgcagtgat
    43201 gaattatgca tttacagatt cgattaaaga ttattttgca aaaaagaaaa tcacagcttc
    43261 acaaatggtc agtggaatga atcatcagca aatgctttac agagatcagg tgaacgaagg
    43321 aacattcaac ttattagatt ctcatgatac tgccaggatc ttgacccttt gccaaggtaa
    43381 caaagaattg atgaagtctg tgatggcctt tatgtttctt caaaaagggt ctccttgtat
    43441 ctattacggg acagaaatag ggatgactgg tgaagatgac ccggattgcc gcaaatgtat
    43501 gatatgggag aaggaggaac aagatctaga gctattcggt tttataaaag aacttgtttc
    43561 tctaaggaaa cagttgtcta agattatttc tgaaggttct actcagtggc taatagtaaa
    43621 tgatcgtgaa gataagctct atttcacacg gaaactagag ggacagatca tctatgttta
    43681 ctttaatcag tcaaaagaac cttgggtagt agaacaggaa aatgaggtga ttcttagtca
    43741 aaattgtcag ttgttagaag acgggaaagc agagatacga caatacggat ttttgatcat
    43801 gtgttgaaaa ctgttaccgg taacaacaag aaagcgtttg caaatgaaga tttgtgccca
    43861 ttataataag ggtgtaacag cacgttgaat acaaaggagg aaatgaagat gaaaaaaaga
    43921 agtgtgaaac agttgggttt agggttaatc tctttaggaa tcttaggcgg attagcggct
    43981 tgtggcaatg gtaactcttc agcagaaggg gaagccgatg aaggaaaaac gttaacagtt
    44041 tccgttgatt ctggatataa agattatata aacgaaataa aaaacacttt cgaaaaagaa
    44101 aacgatgtga aaatcaagct agtagaaaag gacatgttcg atcagttgga atcattagcg
    44161 ttagatgggc ctgctggaaa gggacctgac gttatgatgg cagcatatga ccggatcggt
    44221 gcgttaggac agcaaggaca tctggcggaa gtaaaactgg gaaatgaagc agcttacgat
    44281 gaaacagaca aagcccaagt gacttatgat ggaaaaatct acggagaacc tgcagtaatc
    44341 gagacccttg ttttgtacta taacaaagat ttagtcgata cagcaccatc aacgtttaaa
    44401 gatttggaga atctatccaa agacagtcgt tttgcttttg agtcagaagc aggaaaaaat
    44461 acaggatttt tagctaaatg gactgacttt tattattcct atggtttaat tgcaggttac
    44521 ggtggctatg tatttggtga tgatggcaca aatccttcag atatcggttt gaataatgca
    44581 ggtgctgtag aaggaatctc ttatgcaaca gattggttca aaaatgtttg gccaaaggga
    44641 atgcaagaca taaaaagtgc aggagacttc gccagccagc aattcatgtc caataaaact
    44701 gcagcaatca ttgacggtcc atggcaagcg caaacataca aagaaaacaa tatcaattat
    44761 ggtgtagcca aaattcctac tctaaataat ggacagcctt atcaaccgtt tggcggagga
    44821 aaaggatggg tagtcagcaa ttatgctaaa aacaaagacc tctctcaaaa atggcttgat
    44881 tatgtaacga atcaggaaaa tcaagaaaaa ttctttgaaa tggtaaatga aatccctgca
    44941 aaccaacaag ctagggaaac agcaaaggct aaaaacgatg aattaacaac agctgtgatt
    45001 gaacaatatg aaacagctca agcgatgcca aacatcccag aaatgggcga agtttggaca
    45061 ggtgcagaaa acttgatgtt cgatgcagca tcaggttcaa aaacaccaaa agaatccgca
    45121 gatgaagcag taaaaacaat cagtgaagcc atagaacaaa aatactgatt aaaatgataa
    45181 ccgtccattt ttataaaaaa tggaacaggt gcttcagata aaagtggcaa gagcgagatg
    45241 gaaaattatc ttgctcttgt tgccattatc ttaaaagcag tttgcggttt agcaagttta
    45301 gagggggcat tcagatgcag caagataaaa caagcaatat caacgaaaaa aaaatcacgc
    45361 tttgttcact tattccaggg atggggcagt ttgtaaatgg ccaagctttt aaaggtatcg
    45421 tttttttcgc catattcgtc ctattcattg gtcagatgct tctgggcgga tttcatgcat
    45481 tggtaggatt ggttactttg ggaagtatac caatggaaga tcattcatta tttattttga
    45541 ttgaaggcac tttgcaattc atcattacaa tcattttctt gattttttac ggtttgaatc
    45601 ttttagacgc ttatcgagta gcgaagatgc gtcaagaggg caaaaaaatc aatcggacga
    45661 tgaaggaagt catacataat ataggtgatg aaggttttcc ttatctattg acacttcccg
    45721 cttatcttct catgattttt acgatcattt tcccagtcct agttacattg ttcactgcat
    45781 ttactaatta tgacttcaat catattccac cagccagttt aattgattgg gtaggggcta
    45841 aaaacttttt tagtatcttc tttttaagct catatcgtaa tacttttttt gcagtctttt
    45901 cgtggaccgt gatttggact ttatgtgcaa caactttgca aatcaccctt ggtattctca
    45961 cagcggttgt tgctcaccag aaatttatta aattcaaacg tattttcggt atcattttct
    46021 tattaccatg ggcggtccca gcttttatta ctatcatgag tttttcgaat atattcaacg
    46081 atagcgtagg tgccatcaat actcaagtga ttcctttcat aaaccagctt ccttttgtag
    46141 atatcagtgc aatctcttgg aaaacggacc cgaactggac gaaagtagca attatcttag
    46201 tgcagggctg gttaggattt ccctatatct atgtgatggt tacaggaatc ttacaatcga
    46261 tttcagaaga cttatatgaa gcagcaaaaa tcgacggagc aaatgcatgg cagcgctttt
    46321 caaacatcac gcttcctgct gtcttcctag tggcagcgcc aacatttatt acacagtata
    46381 cggggaattt caataatttc tccatgatct atctgtttaa caatggcggt cccggaagcg
    46441 taggcggagg agctggttct actgatattc ttatttcctg gatctataaa cttacgactg
    46501 gaacttctcc gcagtattct atggcttcag caatcacgtt gattatctcc gtcatcgtta
    46561 tctgtgtgtc attgctggta tttaaaaaga caaatgcgtt caatatgggg gattaacaat
    46621 gaaaaaattt cattcgagtg ctcgattcca aaaacgactt tctcactttt ttacttactt
    46681 ttttctttta atactgtcag tcattatcat ctatccgctt ttgatcacag caagtactgc
    46741 cttcaagtca ggaaatattg cagcttttag tttagatctt tcaagtgact ggactttagg
    46801 aaactttact cggctattca gtgaaacact ttacgggact tggtataaaa atacattgat
    46861 catttctgtc ctaacaatga tcgtacaagt gactgtagta actttggcgg gctatactta
    46921 tagtcgctat cgttttatcg gccgcaaatc aagtttgatg ttctttttag tgattcagat
    46981 ggtaccgact atggcagcat tgactgcctt ttatgtcatg gctttcttat tagaagcgct
    47041 cgataagtac tggttcttga caatgatcta tataggcggt ggaattccaa tgaatacttg
    47101 gctgatgaaa ggatactttg acactgtacc aatagattta gatgaatctg ctaaacttga
    47161 tggggcaggg catttcagga tttttttcca gattgtatta ccgcttgtca aaccgatgct
    47221 cgccgttcaa gcattatggg cttttatggg accttttggg gatttcatgt tagctaagtt
    47281 cctgcttcga acacctgaaa atcagactgt tgctgtcggc ttacaaacat ttatttctga
    47341 tgtgacaaac caaagagtct ctctttttgc tgctggggca attttgattg cactaccgat
    47401 ttgtctatta ttcttctttt tacaaaagaa ctttgttacc ggcctgacat ctggcggaac
    47461 aaaaggatag gagcagagta tcatgcaaac atttccgtta aactattttt ccgcattacg
    47521 tacgccaact caagtgtttg cgggacgcaa actattatca tggcctaaat ttttcttgat
    47581 atttgtattt ttagtttcct tgatggtcat gcctgtgact cttttttatg ccaatcagat
    47641 ccaagcgatt ccattagaac aatttctatc cgttcattcg ctgatcgatg aacaaggaac
    47701 ccaaaaattt tctgaactta aattatctga aactgggtta caagcatcgc aacaaacgat
    47761 agctgtgacc cctgaaattt tggtaggtgt gtctttatct gagaaacaac aatccgatca
    47821 tggaactttt attgattttg agaaggaaca atgggtgatc caacaaaagg ataaatctgg
    47881 tatacgccgc tatacgatga attatagccc atctttccaa ccagattctg tacgtacgcc
    47941 cgaagatttc caacgatttt tagaaagaga attttatgcc agtaatcgtc caacaatcat
    48001 tttatcttat agtttaagtc ttggtcttgt cctatttgtc atgacgagtc tcattttatt
    48061 cggggcttcc tttttcttgt ggatgacaag aaaaagccaa ctttcatcca ttcatacatt
    48121 caaagagagt gcaaatttga tgctgaatgt tatgggaata ggttccatgg cagcagcagt
    48181 tgtagggttt atccactttg actttatctt gatgctaagt gtccaaacaa cgataactgt
    48241 cttgctgctt ttatgggttt ttgtcaaaac aagattcaaa gataagcgtg tcgaatgaca
    48301 agtttaagcg atttatgcga caatgaatgt gaaaaaaatg aaaaataaag tagtttttga
    48361 aaaatttctg aaaaaattaa acttcttagt tgattctttt cttttttagt attaacgtaa
    48421 tagggtagtt tttttaagga ggaaaatcat gttagagaaa actttataca atcaattatt
    48481 ttcacgttct ttctcgctcc ctgtcgaagt aaattattgg gacggtacaa cgaaacaata
    48541 cggagatacg gacactccta cccaaatcaa aatcaatatc catgaagaaa tcccaatgaa
    48601 agagattaca agtaacgcat ctttggcact aggagaagcc tatatggatc atcgaatcga
    48661 gatcgaggga agtatccaag cattgatcaa cgatgcttat cagcaagcaa acagcttttt
    48721 acgaggaaaa gattatctaa aatggctgcc aaagaaagaa aaacatacga aacaaaaaaa
    48781 caaagaagat atccatgcgc attatgactt aggtaacgac ttttataaac tttggctaga
    48841 tccaactttg acttattctt gtgcttattt caatacacct gaagatacgt tggaacaagc
    48901 acaaatcaat aaagtccatc atatcttaga caaactcttt atcaaagaag gcgaaacgtt
    48961 gcttgatatc ggttgtggct ggggaacatt gatgttcact gctaccaaag agtataatgt
    49021 caaggcaact gggatcacac taagtgaaga acaatacgat ttgattacca aaagaataaa
    49081 agaagaacat ttagaagata aatgccgtgt attattaatg gattaccgcg aactaaaagg
    49141 cgaaacgttt gatcatatca caagtgtagg tatgttcgaa catgtaggtt ctgaaaatct
    49201 tgaaggttat ttcaaagtgg taaaagattt attgaaacca aaaggaacag ctttgatcca
    49261 tggaatcagc cgacaacaag gcggtgcgac aaatgcttgg atcaataaat atattttccc
    49321 tggcggttat gtccctggtg ttactgaatt agttgataat attacaaaaa acgatttgca
    49381 actgattgat ttggaaagct tacgtcgtga ctaccaattg acattagaac attggacaaa
    49441 gaattttcat caagtccaag atcaagtcac gaaagaaatg ggtgattcct tctatcgaat
    49501 gtgggatcta tatttacaag cttgtgcagc ttcatttgaa tcaagtaata tcgatgtgat
    49561 tcaatatttg cttgttcaac ctggaaacaa tgacatccca atgcatcgtg cataattgag
    49621 gcaaaagtac tgtttaaaga ctatttaaaa agaagctaag ttttatgatg ctccagaagt
    49681 gaactttttt gtctaacttc taggattgtc tctaaagctt agtttctttt tctttatatt
    49741 ttcataataa aagtttggtt ctttaatttt taaacatgac agaaaatttt ttcttcgtta
    49801 tacttgtaat agaatactat tttataacaa aggggatcga atcaatgaaa aaaactgtta
    49861 tttatactag tttatttgca gctttgtttt tagctgcttg tcaatcaaat accaatcaag
    49921 gcacatctgg gaatacgtct tccagtagcg aacagcgctc ttcacaggta tcggactcct
    49981 caacaaaagc aagcacatct tcgtctagcc agacaaaaag ttctagtgaa gcaagtactc
    50041 agtcagatat caaagtgtct gcagctcgtg cgatcgaatt gttccaagat aaatacccag
    50101 atactgcaat tactagtttg gaattagata gtgattgggg atcttacttc tacaagatag
    50161 aaggtgtcga tgatcaaaaa gaatacgaag caagaattga tgctcaaaat gaaaaaatgg
    50221 agacagagaa tccagaaact ctagatcgag atgaacaaaa tggtcaaaag aaaaaagaag
    50281 atggtctgga tgttgataaa ttgatcacga ttgaggaagc agcaaaaatc gccgtcgaca
    50341 aagtaggaag cggtacggca acagattggg atttggataa agatttaggt actacttatt
    50401 gggaagtcaa agtaaaagac ggcaatcaaa gtacatcagt caagatcaat agccaaacag
    50461 gcgaagtact gtcaactgaa caagatgatt aagaatttct tcggaaaaca agagttgatt
    50521 tttcttttag tcatgataca ctagacaaaa taacttgttt gaaggagcga tttacttgag
    50581 tttagaaacg acctttgcca atcatatctt tgccaatcct ttgatgaatg catctggtgt
    50641 ccactgcatg actacccagg aattagatga actggctcat tcagaagcag gagcatttat
    50701 cactaagagc tgtacgatca atgaacgaaa aggaaatccc gaaccacgct attttgatgt
    50761 tcctttaggg agtatcaatt ctatgggact tccaaactta ggtttttctt attatctaga
    50821 gtatgctctt gcgtatgaaa aagtgcagga aaaccaaaat caaccgttat ttttttccat
    50881 tgccgggatg agtgtccagg aaaacttgga aatgcttgag aaaatagaaa aaagtgggtt
    50941 taatgggatc actgaattaa atttatcttg tcccaatgtg cctggaaaac cacaactagc
    51001 ttacgatttt gaggccactt atgaaacact gaaagaagta ttcagcatct tttctaagcc
    51061 gctaggaatc aaattgcctc cttattttga ttttgctcat tttgatcaga tggctgatat
    51121 cttgaatcag tttccattga cctatgtcaa tgctatcaac agtgtgggca atggtttgta
    51181 tatcgataca gaacaagaag cagtagtcat caaaccaaaa gaagggttcg gcggcattgg
    51241 cggagagtat atcaagccga ctgctttggc gaatgttcgc gctttttata cacgtttgaa
    51301 accagaaatc caaatcattg gtacaggtgg gattcggaca ggacaagatg catttgaaca
    51361 tctgctatgt ggcgcaagca tgttacagat tggtaccgag cttcataaag aagggccgga
    51421 aattttttct agaatcataa aagaattaac gcagattatg tcagaaaaag gatatacgtc
    51481 aattgacgaa tttaaaggca aattacgcac catttcatag caaagagacg aaggtcatga
    51541 ttgatcttcg tcttttttta taaaaaacac tcgtctgttc attcctgtgc aagcgtactc
    51601 attgtatgtt agacgaactt gtgggaaaat aacagaggca aaaaggagga taatatgaat
    51661 gatgcaacag aattagcaaa agagcttaaa gaaaaagaat ttagttttca agaactagtt
    51721 acggatatac agaaaaaaat aaagaagcaa aatcatgaat tgaatgcgtt tgtcgcgctt
    51781 gaaccattcg agagtaattc ccacgagcta ttgattcccc agtcagaaaa agggccattg
    51841 gctggtatcc catttccttt aaaaatgctc ggtcaagaaa aaaagggatg gctagctact
    51901 tcaggatctc gtttatttga aacacaccga gcttctcata catctaatta tgtgcggcaa
    51961 gcagaagcga taggtctagt tccttttgga caaaccaatg cgccagagtt tggtttcaaa
    52021 aatattacag acccagtcat ctatggccca gcaagaaacc cttggaacct tgaatgtaca
    52081 ccgggcggat caagtggagg agctgctgct gcagtttcat caggaatcgt tcctttagct
    52141 ggtgctagtg atggcggtgg ttctattaga atacccgctt cgttttgcgg attgattggg
    52201 ctgaaacctt cgcgagggac gatgccagtt ggtccatatg cttggagagg atggcaagga
    52261 gctgctattg atttcggctt gacagtttct atgagagaca cggaggcttt attttatggg
    52321 atgagaagta tccattccgg tgcgccatat caagtatcgc cagttgagtg gcaaacacat
    52381 ccaagaaaaa aacggttgaa gatagctttt tgtgttgatt caccgatcca ctcacagatt
    52441 agtgaagagg cagtacttgc tgtaaaaaaa gctgtagatt tccttggaaa agaagggcat
    52501 gatttgacag agattcctta cccactagat ggtcgtaaac tgatcacgtc ttattatcag
    52561 atgaatggcg cagaaacagc agcaatgatc cgctcgattg aaacaggcat ccagcgagct
    52621 gtcagaaaag aagaacttga acccatttct tggactttgt tccaatatgg tcagaagctc
    52681 tctgccgcta cttacatcga ttctctgcat gtatgggatg aagcagcaat tgtcatggaa
    52741 aacctacatc aagaatacga tctattcctt tcaccaacga ctgcatttac cgcccctaaa
    52801 atcagcgaag atttgcaaag tgatgcgata agagcacaga tggaacacat cagtgattgt
    52861 tctgaagtag aaggtttaga cgttgtttct tccatgtttg aggagagctt gaagatcaca
    52921 ccttatacac agttggctaa tctgactgga caaccagcaa tcagcttgcc tactcatttg
    52981 acaaaagaaa acatgcctct aggaatccaa tttatggctg ccagaggaag agaagatttg
    53041 ctatttcaaa tcggctatct atttgaagca aatcatcagt tccatttacc aaatccatgg
    53101 aaatagcaga aacaaggaga agaagaatga agaaaaaaag attgtttgct ctaataacta
    53161 gtgccttttt tattttaagc gcttgcggta cagctgccgc taatcaggaa gataacagct
    53221 ggagtaatgt agaaaaaaag aaagaattag tagtagcgac ttctggcaca ctgtttcccg
    53281 catcttatta taatgatcaa aatgaattag ttggttatga tgtagatttg gcaaaagagg
    53341 tggctaaacg gttaaatgtc aaaatctcct ttaaagaata caacgtggat ggacaaatca
    53401 cttctgtttc aaaaagagaa tcagattttg ctgcgaacga ttttggtatc acaaaagaaa
    53461 gagaaaaaaa attctccctt tcagagactt tcaaatattc atttgacagt atgatcgtac
    53521 gaaaaaaaga tgattcagga atccactcac ttgaagatct taaagggaaa aaagcagctg
    53581 gcgaacccaa tactagctat atgcgtttag cggaaaaaca cggagctaaa ttagtcacat
    53641 atgacaatgc cacgaatgat cagtatttaa gcgatgtagc aaatggtcga acagatgtta
    53701 ttctaaatga ttattatctg cagaaaatgg ccgtatctgc tttaccagat atccctgtaa
    53761 aaatactgga gaacgtttat ttcaatgaaa acgaaagtgg ttttttattg aaagaaggaa
    53821 atgatgctct gaaaaagaaa atcgatggcg tattaaaaga gatgaaagaa gatgggacga
    53881 caaagaaaat atctgaaaaa tattttcaaa ctgatgtttc agtcaaaccg aaagaaacga
    53941 tggctgagtc ggtgagtgag tgatgtactt tcctctaatt gatttttccc tcatgtggac
    54001 ttcacttcct ttcgtactgc aaggcttggt atacacatta gggattggct tcgtgtcgtt
    54061 tcttttagga aatctggtag ggttgctttt gacagtttta ggtcttttgg attggctgcc
    54121 tctgaatgta tttattcgtt tttatttatc gttctttaga ggcattcccg cactagtcct
    54181 gctgtttctg ttatattttg ggttacctta tcaattaagt gccttaacgg cttcagtcat
    54241 ctgctttacg attaccagca gtgcatttat tggtgaaatc tatcgaggat cactagcagg
    54301 cgtttcttca ggtcagtggg acgctggttt agcttctggt ttttctttct ttggggtatt
    54361 gaaatatatc gttttgccgc aagcttttcg aatctcagta ccggcactca gtaacgtagc
    54421 tatggatcta gtgaaaggta cttcgttagc agcaacaatc acagtgccag aaatatttca
    54481 aaaagcaaag atcataggcg gtcggacatt cgattatttt tctctctata ttttagttgc
    54541 actgatttat tgggtcattt gtatcgggat cgaaaaagtg caacagtatt tagaaaaacg
    54601 ttctatgcat cagtcaatct gaaaaataga aatggtgcta gcgtggctgg caccatttct
    54661 attttttgtt tcttgtatat tctgcctagt attttaaaac catttcatgt aaaatgtaaa
    54721 tcgaaaatat gttcggaggt agaaaacatg aagaccccgc taaccatcga aatagaatcc
    54781 tcgttatacc aatattgcat cgagcaaggc ggcttggttg tagaagaagt cacgatgcct
    54841 gatgaccaag gaattgtaga tacgcttagc tgcttgacaa aatttgatgg aagccgagaa
    54901 tggcgatgct atgagctgaa agtgacaaaa gcagattttc gctctacagc caaactgtca
    54961 tttgttggac attataatta ttttgtttta ccaagtaaac tatatgaaga agtaaaaact
    55021 gaaatcccta caggaatagg tgttttagtg tatcgtccgt acacggttga agaggagatg
    55081 cctgcctctg gtacatttct gattgcgaaa aaagcagcaa agaaagagct tgctgtaccg
    55141 gaagaagctt tgacaaaccg cttcatggct tctttattca gggaagtaag aaaagcaaag
    55201 caaatggagc gaggcgtaaa atattttcca acagatcaat tgtacaaaga attgaaaaga
    55261 cgttcagaaa atcaagatcc attttctaac gaacgatatt atgaacggtt tttagaggaa
    55321 atagctagtc aggcaatcaa tgagttgcaa gaagaagtta tcgcgcttca gcatgattat
    55381 gaatatttga ggcaacaaca gcagatccgt cggttgccta cagagccatt ggagtgaaaa
    55441 atatgtacta tccttattta agaggaaaac aatttgacct attagcatta aaagaagcac
    55501 tgtcgcgagg attgctctcc aataaaatcc aaccagtgat cgaaccagta cgtgattccg
    55561 ctacgcttaa aaatgtgatc gaattatttc aaaaaaagca ccatcgaatc gctgtgatcc
    55621 aaaatcccca agtaggacaa ttcaaattat tcgatcagca tgtgcacagt tggacagtca
    55681 aagaaaatag ctctgtcgtc cctgcacaga tcttaacgcc agaaaatctc agtgaagtac
    55741 tggattcacc tccagcgttt cttgttttcg atggacagca ctacccaaaa gatacagagg
    55801 tgtggaaaca gttggcagga gttgattcga aatttttgat accagatact agtcgctttc
    55861 gcatctggct gcccgaaaac aaaattgtga tccgtgactc ttttcaaacg agaaagcatg
    55921 ttgaaagtta tgcagataaa acagatgact tttttagtga tgactatctt tttttccacg
    55981 cagacggata tattggattt tctgatttca cgatcgaagg tagccgttat ttcgataaag
    56041 ggttccctag ccgagcgctt gctatccatc taacgtatat tgatgcttac ggcaatatac
    56101 gcgtgaaaca ttttgtctct gacagtaacg actctgctaa agaccaagca ttgaagtttc
    56161 ttgaagcagg agataaaatg aaaaaatgga tcatgcgtca ccatcatcaa ctcttgatta
    56221 cttcaggaat gattgaatta ttggctcttt accagcaaca aaaattccct ggactgggag
    56281 tgttgaaaaa gtggtcactt atgcatcatt tggaacttat tagtcacctg ctagatcatc
    56341 caaaagattg gcttaaatat tattcaaaag ttcaggaact atatgaagtg atccaatgat
    56401 tagataatgt aaatgaaaaa ggaatagaaa agaggaaact ggatgtatat tcggcaaaca
    56461 aggaaagaag aagtagaaga agtggtagaa atcattaatg ccgcagcgga tttcattgct
    56521 tcgcaaggct ctcctcaatg gcaaaacggg cagaaaccaa caaaagaaac gattttgaac
    56581 gatattgaaa gaaaagaaag ctatgtatta atagtggaag atcaaattgc tggaacagct
    56641 gcattagtct caagcgtgga tcccgtttac acaaaaatag atggtagttg gaaagaatca
    56701 actggtcctt atttatcgat tcatcgtgtc gctttagcag aaagtactcg aggaaaaaaa
    56761 ctagcaaaac cgttcttaga acatttgttg acgattgcag ccagcaaaaa tatccaagat
    56821 atccgtatcg atacttatcc agctaatgaa ccgatggaaa agaccatcta ttctgctgga
    56881 ttcacttatc aagggatgat tgaatttcct tttgaacacg gcgaaagaaa agcatatcaa
    56941 ataatcatca attgactata aaatcatctg agcaaagata aagacattaa cactactgaa
    57001 aaaaacaatc atatgatagc caagaggttg taacagaagt ggccagcttc aaaaaacaag
    57061 aaagaatttc cgaaaatgct tctcaaattt ttgtggaatt ttagcgtatt ttacgaaata
    57121 gctgctttct gaaactccct tcatcgagag gtcgtgacat agcttttgtc acgacctctc
    57181 ggcttatcct acgagtatta ttcgatacat ttatatcaat aatccttttt ttattttatc
    57241 tgcagcttct tggaacgctc catcgtttga cacgactaaa agtgagggga tagctttcaa
    57301 acgtttcaac tgtgctaaat cttctacata aaccgccagt ctggctgaaa tctgttcaga
    57361 tgaatctcca cgttttttca ggcgcgattg caatgtttct ttagagatcg taataaagat
    57421 aggacggact accgtcccga aatactcata taaatgccaa aaaccatttg ctgtcaaaac
    57481 ggcgtaacaa tttcctactg tcagtttctt tttaatttct gctttactgg aaccatattt
    57541 atgttgagca tattggtccc actctgcaaa ctcatttccc ttgatcatct gattgaatgt
    57601 attgtcagaa acaaaataat aatcctcttg atctttttcc ccaggtcttg gtgatcgatt
    57661 cgtgtaagta atgatctttt gttccggctg aaaaatagct tctgcgagtg aagtttttcc
    57721 agaaccagaa ggaccgataa atacatagca ataattcatt gtcatttctc ctttgatgat
    57781 tgaacaagtg aaaaagcttt ggaaaatatt tccaaagctt ttaaaagtaa ctttgctttt
    57841 ttgtatatta taccagcaag ccagtcacaa tagcacttaa aaagctgact aaagtcgctg
    57901 ttagcaaaat tttcaatccg tgttttgcga caagatttcc tttttcttca tttaatccct
    57961 tcatcgcacc agaaatgatc ccgatagaag agaagttggc aaatgaaacg aggaagacag
    58021 atataattgc tgttgtacgc tcagtaaaat ggaaattacc atttgctaat tctgtcatag
    58081 caacaaattc atttgtaacc agtttagtcg ccatgatact accggcatcc actgcttctt
    58141 tccatgggat tccgctgatg aaggcaagag gggcaaagat gtaacctagg atctcttgga
    58201 aagtgatgcc gaatatcccg tggaagatag cattgatcat ggcaatcaaa gcaacaaaac
    58261 cgataagcat agcagcaacc gtgatcgcca catggaaacc atcaagaatg tattctccca
    58321 acatttggaa aaatgtctgt tctttgtttt cttcaatgat cagctcatct tctttttctt
    58381 ctaatacata gggatttaca attgaagcca gaatataacc gccaaataag ttcaaaacaa
    58441 gggcagtgat cacatattta gaatcgatca gtgccatata agatccgacg atcgacatag
    58501 aaactgtaga catagccgat acactcatgg tgaacaaacg tttctcagat aggaagggta
    58561 attccttttt tatggaaata aaaacttccg attgtcctaa aatagcagaa gctactccat
    58621 tataagattc caatttgccc atcccgttga ttttacttaa tcctagacca acagctttca
    58681 taaataatgg aagaatcttg atatagcgta gaataccgat aatagcagaa ataaatacaa
    58741 ttggcatcaa tacggaaaga aagaaaggtg cacttccttt atttgctaca ccggcaaaaa
    58801 caaagtcaac accttgccca gcaaaagcaa gaagatgatc aaacattttt gccaatacag
    58861 aaacaaccgc tgtaccaaaa gttgtacgta ataatacgaa accaagaaca agctgtaaaa
    58921 cgaacatcac aattagtggt ttcaatttga ttgctttttt gttactgctg atcaaaaaag
    58981 caagccctaa tgtgacaaat aaaccaataa tacctaataa ataactcaaa taatcactcc
    59041 tattccaaat tccgttttat tttacctgtt ttgcaaataa aatactaatc tttagtgaaa
    59101 ttttcattac ttttttagag tgaaacgcat tcattttcca ttagaaaata aagcgaacaa
    59161 aataaaaggt ttaaaaagtg taacgtctta gtaaagtcta taaaaaaacg aaactatcga
    59221 ttaagctaat agtttcgttt tcaacattta taagtaaact ttttctattg gtaatataga
    59281 ttttcggaag ggtagacagg tgcgcaggta atatcgattc ctagtttttt caatgtttgt
    59341 tcatcatttt tattgaccat cacagtagag tgggcttgtg ctccctcaag ttcagctagt
    59401 ttatcataag caacttgagc gattggattc gttactgcac tgattgataa agcgatcaag
    59461 acttcattga tgcttagtgc atccaaagag gaatgaagtg tctttgattt caatccttgt
    59521 attgtttcaa gaactaatgg tgacaataaa ggaatgtcat ctgcgatatg ggctaaatgt
    59581 tttactgcat ttaagataac tgccgctgac gcatccatca atgaacttgt acgcccggta
    59641 atgatgactt catctggtaa ttcgattgca atcacagcag aaggatcttt tgtaggactt
    59701 tgcgcttgaa tcttatctgc atagtcatgg gcagggacta ccacgtttcg gtcttcagga
    59761 cgtaaaccga cttcttccat aatcagtttg attcgattaa ctgcttcttc gtcgatcaat
    59821 ccttttttga agtcgcattc tgtttggaaa taacgacgga tgatttcttg tttagaggct
    59881 tcttggacaa cggtatcatc cacgatccca aatcctacac gattcacacc catgtcagta
    59941 ggagattgat aaacagattc tttaccagta attttttcaa taatacgttt gattacagga
    60001 aatgtctcaa catcccgatt atagttcaca gctactttat tgtaggcatc aaagtggaag
    60061 gaatcgatca tattgacatc ttttagatcg actgtggctg cttcataagc aatgttcagc
    60121 ggatgtttca acggaacatt ccatactggg aaagtttcga acttggagta accagctgca
    60181 tgtccttttt ggctttcatg atacagttgg ttcaaggaag tagcgagctt tccacttcct
    60241 gggccaggag ctgtcactac aacgattggt ttagttgttt caatatactc attttttcca
    60301 aaaccatctt ctgagacgat tttttctacg ttgactggat agtcttcgat ttctgagtgt
    60361 ttatagacct tgatgtttcg tctttctagt ttattgataa agactttcgt ggcaggctgt
    60421 ccactatagc gagtgataac gacactgttg attaataagc cataaccacg taattcatcg
    60481 attaaccgca agatatccat atcataagta atcccataat caccacggat cttattacgt
    60541 tcaatatctc cagcatagac gcaaatcagt atttcagctt gatctttcaa tttttgcagc
    60601 aatttgattt tcgcatcttc ttcaaatcct ggaagtacac gtttcgcatg cttgtcgtca
    60661 actagcttcc caccaaattc taaatataat ttgtcatagt ggttcactcg ttccaaaata
    60721 tacgctgact gctcttcaat atatttttct gaatcaaaac caattttttt cactaggttc
    60781 cctccttaag tactaaagca ttttttcatt tttttgagga ttcgtcaact ggaagagcga
    60841 aattcctcaa aaaaacaaag aaaatggttt aaaccaactt gtctagatag ttattcattg
    60901 gtatgatagt ttttgataag gaaggtgcta catgaaaaaa agacagaaaa agaaaaacgc
    60961 atataaacac tatatccgtt cgatttttac cggttatgaa agaatgcttg aagatcccga
    61021 attggaacaa ttgacgttta cttatctaaa cgaagaaacg cagctaactc gtgatgagca
    61081 tcagcgcatt catttcacaa caagagatct gcctagtaaa taaaaaataa gataaaggtc
    61141 atcggattcg attctgtcct atcagatgga aagactagtt gatcgaaaaa aaggctgtac
    61201 caaattttgg tgcagcctgt tttatggagc attgcccgct cttttttata acaatttttt
    61261 acagaaaatg gtactattga agtattaata agtgaaaaac agatgagtaa gaggaggcaa
    61321 gtagtatgaa agagccagat acaaatgcaa attatgagcc agacgaacta gaggagacga
    61381 atgcggatca ggatacagga caagaatcgt cttcttttta cgatatcaaa gaaaaagcaa
    61441 gcatgaatct ttcccaatta ttagaagact tacaggcttt tgaaaaagct gtccgcgaag
    61501 aagatatccc tgagatctac cgtttataca atggccgatt gaatgaagaa ttaaaaagaa
    61561 gctcaaatga aaatcacgag atcgatcaat tgctgatgcg taagatccat gatcgttttt
    61621 tacaggaatt tccttttatg gaacaagtag aaaacatctc gccaacgatg agctattaca
    61681 aaatcggcac ttattaccat gatcggccca cggtcggtat tgatgcaagt ctgccagaaa
    61741 tttttgtttt gcctaagatc gatgaagagt gggagaaata ttcccaaccg gagtcaacgg
    61801 actatgacaa aaaaatcaat gagctagacg caaaggtgat cactgctcag acagaaattg
    61861 aacgtttaga tgaacaaata aaagaaatca atcgacaaat gactgatttg aacgacaata
    61921 aaggattctt gaatcgtaaa aaaatcgagg aagaaattca agaattagag aagaagaagc
    61981 aagtactatc taatgaaaaa ttaggctggc ttccttatat tgagacgcct gaaacaatcc
    62041 agcagcaaaa agaagcattg aagcaagaag caagagcaga ccagcttcgt gcagccatcg
    62101 tagaaaaaga acaaaggcaa atcagacgct atttcggtag caaagaggga ttcggtcaag
    62161 caatccatga attcttgatg aattatcttg gcaatgagaa tcctaataat caatctaatg
    62221 aaggaggttc cgagtatgaa tgaacacgat gaagcagaat ggacaaaaaa tgaagaacaa
    62281 acagaagatc atgaagaaac gaacacttca ttggaagaac aaacaagtaa tcctctggat
    62341 gacacagaag aaatccctat gctagaggaa acaaaaatac acgaaaaaga aaaagtaact
    62401 ccgacgaata cgaatactgc agaaaacacc catgcttacg aaataactga aaatcccggg
    62461 tatttagaag gaaaagagca agatcatcaa gatatcgtca gtttgattga aacagcggaa
    62521 gcagaattag cggatttacg tatgagaaaa gatttgatcg aatcagattt tccacaatta
    62581 ttagaatcat atgatcgttt tatattgaat gaagaaccaa tctccacgat cggaaagaca
    62641 agcctgatcg aatacttcac gtatgaatta ctgaaaccgt tgaatgatat tggtctggaa
    62701 cggtcaaatt cagcttatga cacatggaaa acaagacatt tttcgatcaa ttatacgttg
    62761 aatggacaaa acgaattagt cttttccttt gtattaccga ccatcgatca acgataccaa
    62821 gtggaatcga tgagtctcct aaacgtatca ccagagacaa tggaaatcaa tgtccaagat
    62881 gaccgggtgc tttctttgat ccgacactgg tcagtggatc gagtattctc tgcagggcag
    62941 atcacgatat tcaatcacaa attgaatcaa ttgcccatgc aagaacactt ggttttaccg
    63001 ttaatcagac attactagac aatacgaagc cacttcgttt gaatcttcag agcgaatttg
    63061 aattgacgaa tgaagtattg gatgatattt ttatcgtggc aatgaaaaat ccatcctacg
    63121 atatggaaaa gatcaacgaa actacttatc aagtacgatt agataaagga cagtctttaa
    63181 cgataacaac aaacgaaaaa gatcaaacag tcttgtcgat ctcatctgga gactacccac
    63241 gatctgtcat tgatttcttt atcaattacg aattcttggt cccattaatg gtgagaaagt
    63301 cctgattgga taagttggat taccagatgt cattcagata attctgttcc aaaggacttg
    63361 cggcagttat ccagaataat tgtcacaagt cttttctgta tgtactaaat ggacgtgaat
    63421 aacttgctga tgaaggaggg atttcattag gaatgtccac aaataaaata gcacagctta
    63481 gcttattgtc tgctgcttgt gtagcaggta ggatcgcttt tcaatttatt ccgaatttcc
    63541 agccaatgac tgctattttt ttatttatag tactttactt aagcttaaaa gatgcgttaa
    63601 ttgtcatgag tctttctatt gcgatcagca gtttttattt tggtgttgga ccatgggtca
    63661 tcggccaatg gatcagctat actgttgttc tgagtttgtt ttcaatcgtc tgcttgagaa
    63721 aaacagtgca aaggaatcta tggttaaagg gagtctgttt ttttctggcg ggcatggttt
    63781 acggaatagg tatgaccgtt tttgatacgc tgttatatcg tttgcctcaa ccttggatct
    63841 attaccttca aggggtgtcg tttgatttga tgcacagtat aggcaatgtt gtgttctttc
    63901 ttgtttttct gccagtcgtc aaacgttttt acaatcattc aggaggaaaa aatgaaaaaa
    63961 ataatttata gtttgcttgc aatgagtgtc agtatactca ttttgacaag ttgcagtaca
    64021 acctatacac aatcggcttc caaccaaaag gaggaagtaa aaacatcgca aaaagcaaca
    64081 atcacgttac aagaaaatgg tcaaaacttt tcggaaaaag aagtgttctt caaaaaaggc
    64141 gatgatttac tgagtatttt gaaacgaaat tttgaagtca aagaagataa cggcttcatc
    64201 acttcgcttg aagggcactc acaggatgag aaaaatcaac tctattggat gtttactgtg
    64261 gacgggaaaa gtgctactac tggtgccaaa gagatcaaat tgaatgatgg acaatcggtc
    64321 attttcaatt tgtctaaact ataagtttca taaaaaactg ttaaagggcg aatattgcca
    64381 taattcagtg agttcagttg atgaaagaag gaaaataaca tggaaaattt taaaaaaagc
    64441 ggaatgtttt ccgtaattgc tgctctaggg gctaatattc tagttgctat cagcaaattt
    64501 gtcggctatg caatcagtgg cagtgccgcc atgctaaacg aaagcatcca cagtatcgtt
    64561 gattgcagca atcagatttt gctgttattc ggtgataaac aagccaataa aggacagagc
    64621 gagttgcatc aatttggtga aggacgagca aaatactttt tcagtacaat cgtcgcaatg
    64681 atgcttttct tcggcggtgg ggcacttggg gtgatggaag cttttgaaaa gttgacgcat
    64741 ccatcccatg aagtgggtaa tccgatcatt gttatagcaa tactgttatt tggtttggta
    64801 atcgaaggaa gttcgttacg cgtggcaatg aaagaaatca aagaattgaa tactgaaaaa
    64861 ctttccacga tgcgcttttt gcgcgaaagt cgacacagtg aaatactgat tatttttacg
    64921 gaagacttgt gtgctgtaat cggtttggtc ttggctttag caggaacaat attgacttat
    64981 gcaaccggga ttgctgcatt tgatgcgatc agcggattgc tgatcggttt cttgctgatg
    65041 ggagccgcca ttttcctagc aaaagaattt tatagtctga tcatcggtga aagcgtgaca
    65101 gcaagcgatt tatcaaaaat caagttagct tttgaacgtc ctgagatcag tcggctgatc
    65161 gatataaaaa cagttcattt aagtccaacg gagattttag ttgcagcaaa agcagatatc
    65221 gttggtaaca aagagaatga agcttactcg gtcatcaatg atattgaaaa aaatatgcgt
    65281 cagtctcttc ctgacaagaa gatgtatata tacattgaaa cagataaata tgacccaaat
    65341 tattctcgta aataaaacgt ttattcatga attgaagcaa aaatgagaaa aatataatct
    65401 tgtttttaaa taaaacggct acaatttagc gaatttatgt tacaatgagt ccgctgttta
    65461 tttgttgtaa ttaaaggaga tattttaatg aacaaaaaga aaagtgcgcc atggcttcaa
    65521 gctttgcatg cagtgatgcc actttgtata agctatatac cagtaggatt agcttgcgga
    65581 gtattgttgc aaaaagttgg atttgatcct ctcttatcag gactgttatc gattctggtc
    65641 ttttccggtg gcgcgcagtt tttagttgca tctatgctta cgacgcaagc atcatttgca
    65701 acgacattat tgatggtttt ctttttagaa ttacgctata cattattagg agcaagtctt
    65761 gccggtttta tgaaaaaaga aaagcggacg tttttggctg tcttttctca atcactgaat
    65821 gatgaaaact atgcggtgaa ctacttaaag ttttcaactg acccttcctg gaataaaaga
    65881 aaggctttat atgtcaattg gttctcaatg actgcatggg ccggtagcaa tatgatcggt
    65941 aattttttcg gctcggtgat tcgagtagat gctgaccttg tccattttgc tttgacggcc
    66001 atgttcattt tcatgtttat catgcagatg aaaagcgcac tactgatctt tacaggttta
    66061 ttctcaggcg tattaggggt cgtattcatg gtattattcc aaaatacttt cggattgatt
    66121 gcagcaacag tcattgcttc atttgccgga tttatgctgg agaaggcatt caaaaaagaa
    66181 aaagctaaga aactaagaga ccgcggtaaa gatgtcaatg agccgctctt caacttcccg
    66241 gaacaggagg ccaatcacca tgactaaact atatttgcta cttttagttg cttgtctgtt
    66301 catcgtggca tatatcccgc gcttgttccc gatgctttat tttactcatc gaaaagtgcc
    66361 atcctggttc agtgactgga tgaaatatgt accggtggca ttatttgcgg cgttagcttt
    66421 taaagatgtt ttcattactc atgaacatct ggatattgct tggaatatca aaatagctgc
    66481 aatgattcta gtagcaggcg tggcttacaa aacacgttcg atggcgttgt cagttttgac
    66541 aggacttgcg tctgtctttt tgctgtctat gctttaaact gttttatttt attaaaaaca
    66601 gagattgcga cataagttgt tcaaactgat ctatccgaac tgcatttgca acagtcaatt
    66661 ctggatgcaa gtttattcgt agggataaaa aagattagtg ttggcttatg atgcaagctc
    66721 ttttttattt taggaattag agagggattt gtccttctat gattttttgc tataataggg
    66781 aagatgttta ttttatgaaa gaatagttga gggaatttaa atgaataaaa aattgatgca
    66841 aggaacattt tggctaacct ttgctaatct tctatgtaaa gttttagggg tagtctattt
    66901 gattccctgg ctaagtatga tggggaacaa tcaagatggt atgcttgcta cgacattgta
    66961 taatgttggc tatcttcctt atggattgtt cctgatgctt ggtacagtcg gatttccaaa
    67021 tgcgattgca aaaaaagtag ctgtagccac aaaagaagga gataacgctg cttgtcggct
    67081 gatttttaga agtacgatca atatcatgtt tgtcatcggt atcgcctctg ctgcactgat
    67141 gtatttattt gctcctttac tagccggaat cagtccgatt gctaacgtta ataatgggat
    67201 actagctatc agaagtttat gcccatcttt gattgctatc ccaattctta gtgcaatgag
    67261 aggatatttc caaggaaaaa atgatctgcg gccttatgga acttctttga ttatcgaaca
    67321 ggctgtgcga gtgatcgtta tcttggctgg tacttattac ttgcgcgtat tgactgacgg
    67381 aaccatatta gaagctgtat tgatcagtac agtcgcttct ttcttcggtg ggttagctgc
    67441 gattatccat atgtatatcg tcggacgcag aaaagacttc ttcgaactta aagatttttt
    67501 gatttccagc cgttatttcg aaagagaaaa ccgatctgcc tctgtctcta tcattcggga
    67561 aacactaccg tttatttttg tcggctcagt cattactatc gttcaaatga tcgaccaagt
    67621 aacgatgaaa ccactgcttc actttttccg tccagagatc gcagatcagc aactggaatt
    67681 cttattcagc cgtgcttctg tcaatccaaa taaattgaca ttgatcctga tctccatggt
    67741 aggaacagta gctataagca gcttgccaat attaagcacg atgaagaaaa aagatcggat
    67801 acaaatcgaa aaaacagtag gagatagttt ttcgattgcg ttattgattc ttcttccttc
    67861 attgactgga atgtctttat tagctggacc actatacaca ttgttttttg gctatgatcc
    67921 tgaaagtgtc ggatatttcc aaatggcttt gctagcttct ttgtttttct ctttattcac
    67981 gatcctatct acgatgcttc aatctttgaa tcaccatcgt tttgcgatcc gattaactgt
    68041 agaagcaatt atcctgaaag tcatcttcca agtaatcgga ttaggattag ttggcggata
    68101 cgggatgagc ttatcaaatg gcttagcatt cggtattgtc tttgttcgcg gctatcactt
    68161 tatgtgcaaa gaataccgaa tagcaccttt agcaaagatc agcaattttt tcttaaaaac
    68221 tttccgctcc accctgatta tgcttgcagt atgttttgcc gttttctttt tgctgaatca
    68281 gcgattgtca atggaatcaa aaagctatgc aatgatttat tgtgtggctg taggaagtat
    68341 tggcggctta gtatttttat tttctcaatt cggaaaaaat gggtttcgaa tgttgaaaaa
    68401 tgttaaacat catagcagaa gcaaagaata ggttaactaa tcgttttttg ctgtcacttg
    68461 aaaaacggca actcgtatga ttacgcttgt cgtttttcta ttttccaatt ttagtttcat
    68521 atctaatctt acttatgata tagttataag gtctggaaaa attctttgaa acgaggaaat
    68581 taaacacatg aaacttgcag tagttacaga tagttcggca tatctgccgg aacgtatcaa
    68641 gaaccatccc gacttattcg ttattccaat ccctttgatt atggatggga aaatttataa
    68701 cgaaggaatc gatatcgaag cggatgaata ttatggactt ttaaaaaaca gtaaagattt
    68761 tcctactact tcacaacctg tcgtagggga agttttgggt ttatatgagg aattgaaaga
    68821 gaaagggtat gacacgattt taagtatcca tctttcttca gggatttctg gctttgtcaa
    68881 cacattattt gcgatgaaag atgacatcag cggagtaacg gtcattcctt atgactctaa
    68941 gatcactagt atgccgatgg gacacatggt agaagctgcc ttagacttaa atgatgaagg
    69001 tcagtccctt gatgaaatac ttgcacatat cgatcgaatc cgagataata cctacgctta
    69061 tctgattgta gatgatttga acaatttagt acgaggagga cgtttgacaa atggtgcagc
    69121 gctgattggc agcttattaa aaatcaaacc gatcctgaca ttttctgaag ggaaaattgt
    69181 tttattcgaa aaaatccgtt caagtaaaaa agcatttgct cgagctgaag aaattattgg
    69241 tagaagaaat aacgaaatac aaccgccagt caaactttac gtgatacatg caaataattt
    69301 agaagtagcg attgcggaga aagagaaatt gcagaaaaaa tatccaaatg cagaaatcga
    69361 aattggtcat ttcggaccag tcattggtac acatttaggt gaaaaagcca tcggcattgc
    69421 catttcagcg caataattcc ttttattcaa aaaacatacc aaaaatattc caacatcatc
    69481 ttggactttc tacatgttac taatgagcgt gtaaaagaac gagatggtgt ttttatttct
    69541 atcaatgaag ctctttttct ttgcaatcct cacttcaatc ctctataatg tcgcatatag
    69601 tttagtaaat gagtaaacta ctaatttact tatttactaa aaataaaagg atgaggagtt
    69661 aaaataatgg aaataccaac aaatttaaaa cataaaccag taatcgttgt agaagactat
    69721 gataaagttg atggaagaaa tgcattaaat acggatgcaa aagggctttc actgggcctt
    69781 gctcagtgga atgatcgtgg aaaagtcgat atctcaggca aggtatggcg acatactgga
    69841 gaaaaatggt cacgacagtc ggaagaatta ccaatcacac gtattttaga tttagcgatc
    69901 ttagctgcac aaggaagttt atacttccaa gatgcttatc gttatgaaaa attttatgat
    69961 ccagaaaatc cagtcgtaga catcattgga ttacaaggga accgaatgac ggtagaagta
    70021 gataccaaaa atccaaagat cgatgaagac atcattttgt attacgatac actacaaaaa
    70081 gacggagaac tgattgggga acgattccgt attttaaaac gtcttttaga tgagctagga
    70141 tattaataga cagagatgat caaaagggga agagaagcat ggagaatttc tcactaacag
    70201 aaaaccgaac cttttcacgg ctagaaaagc aaatgatctg gaagaaaccg aaaagccatc
    70261 ggacaagtgc agaagaatgg cggatcgcct ccgaaatcaa agggaattgg caagatcctg
    70321 aaatgaaaat cagtaacgta cttttggaag gagatgccgg gtcggggaag acacaattag
    70381 ccaaagcact atctgctgat ctgcaacttc cctatacaaa agtgacctgt tttgcagata
    70441 tggacaaatc agatgttttc ggagccttat tacctgtagt agattctaat aaggaacaag
    70501 accaagaatt actagaagct atttaccaaa cagatacact tgaagctgta ctgacactga
    70561 tccagaacca ttacggcatt gatccttttt ctgctaaaga aaaattagca gagctagttc
    70621 aaaggatcga agctgattat ccagatgcaa tccattacag ctattaccct tctgaaatcg
    70681 ttcgagcgat tgaaaaagga tatttattag agattcaaga gccgactgtc atccgagatg
    70741 cctctgttct tgtggcactt aactcagcgc tcgaaccaaa tgggatgttg aatttaccga
    70801 caggaatcat tcgtcgccat ccagattgcg tcattgtgat cactacaaat cgaaattacc
    70861 aaggaaatcg cccattaaat gaatctttaa gagatcggat gcaacatgcg gaaaaaatgg
    70921 atcttcctgc cttagaagtc atggcagaac gtgcgatggc gaaaactatg atccaaaaac
    70981 aagaacttct cttaaagatg gcagagatta tccgtttgtt ggatgaaact gcaaaagcta
    71041 acgccatcaa aggtgtagca ggaatgcgtt cttattttta ttgggcaaat acctataagc
    71101 aaggacaaga tttactccag tcgatttatc caaaagtttt gtataaatta tccactgatt
    71161 cagatgaatt ggcaattctt gaacaagctt tgtctgacag tggattgcta ctggaacttc
    71221 aggacatatt gagaaaagaa aaatggggtc atcctcaatc tgagcataca aaaggaagaa
    71281 ccattagcgc cgaagaagca aatgaacgaa acatcactga aaatgctgaa gaaattctgc
    71341 gcttagatga aaagaaatcg ttgtctgctg aagaaccaaa tgagggagaa gagaaacaag
    71401 aagaaacaat agaaaaaaac gagattcctc ctcaaatgca aaaagaacgc agtagcgata
    71461 tcgaaggaaa aaatcaaaaa gaacaacaaa caggagatga ttctcaagaa atgtctgctt
    71521 ctgacatgga agcacatgat aaggaaatca agaagcaact gaataaagaa gcgcgacaaa
    71581 tcatgaagga aacgattcat gaaaaagaag gtctcatcgt tcaccgacca gctttccaag
    71641 gaaaaacgcc ggaagcacgt gagctacaca tgcaagtaat gccaatagta gaatcactta
    71701 gccggcaaat tttagagtta ctggataatg aacaaacaga gacgtaccaa aaaggaaaat
    71761 acgaaggtca gcggttcaat gcaagcaaag tagcatatgg tgatttgaga aattttgaca
    71821 aaaagaaccc gccacatgag caaccttctt tagcggtagc tgtacggatc gatgaatctg
    71881 ggtcaatgat acgggatgat cggatcgaag cggcaaaaaa agcagcgatt gccattgccg
    71941 aattttctaa gaaagtcgat atcccattgt tgatttacgg agatacagca gaccgttcgt
    72001 caagagaaaa gacttctttg ttttcttata aagaatttga agacggattt caatggttaa
    72061 atgaaaaatt agtcactatg aaaccaaggc aaaacaatcg tgatggtgct gcacttcgtt
    72121 tagcagcaga aaaattaaac agacaatccg caacaaccaa actgttgctt aatattagtg
    72181 acggtcagcc aaaagcgttg ccggattata caggcaaaaa agcaaaagaa gatatccagt
    72241 ctgttttgaa agaatatgaa cgtcaaggaa tcctatttgt ctccgcagct attggccaag
    72301 acaaagaaga aatcaagtcg atctacggtg aaagtcgttt tgtagatatt actgacttga
    72361 atgaatttcc caagcaaatg attcaactga ttgcccgcta tctatgataa aataaagctc
    72421 aacgaacgca cttagcagat tcgttgagct tttcgtttct agttaccggt aacaaggata
    72481 cttctaaaat agaatcggtt ataatcaaga gggaccgtta aaggagtgaa acgatatgat
    72541 acaagaacaa aaatggtgga aagaagcagt aggctatcaa atctatcctg ctagtttcaa
    72601 agatagcaat ggcgatggtc aaggagacat caatgggatc cgtgaaaaac ttaattattt
    72661 gaaagatctt ggtatcggct ttatctggat caatccgatc tatcaatctc catttgtcga
    72721 taatggttat gacgtaagtg actatcaaga tatagaagag agattcggaa cgatggaaga
    72781 ttttgattta ttgctaaaag aagcacatga attagggatc aaagtgatta tggatcttgt
    72841 catcaaccat agttcggatc agcatcaatg gtttgaagaa tcgaaaaaat ctaaagaaag
    72901 cccgtatcgc gattattaca tttgggtcga cggggtagat ggcaaagaac cgaataattg
    72961 gacatcgatt ttcggcggtt ctgcttggga gtattctcat gaaactggac agtattatct
    73021 gcatgttttt gcaaaagaac aaccagactt aaattgggaa agcgagaaat tgaaagaaga
    73081 actattcaat atgatccgat ggtggttgga taaagggata gatggatttc gtttagatgc
    73141 gatttctcat gtaaaaaaag atgaatattc agtaaaagcc acagagaacc ctttctcacc
    73201 ctttcaaaat gtctcaggaa tcgaagaaca tttgaccgat ttgaaacatg tttttgaaga
    73261 gtacgatatc atgactgtcg gagaagcaag tggtgtcact gcagaagaag gaccacaatg
    73321 ggtagggaaa gacggttatt tcgatatgat attcgaattt gatcatatcc atatctggca
    73381 gcaagaaaaa gaagggcaat tagatgtcct taaattgaaa cttgcattaa gcgcttggca
    73441 aacttcattg gatggtatcg gatggaacgc tttatatatg gaaaaccatg atgttcctcg
    73501 tgccgtttca gtgtttggag atactcgtcc cgatttttgg gctatgtctg caaaagcaat
    73561 cgctatgatg tatttctttt tgcaaggtac gccatttatt tatcaaggac aggaaatcgg
    73621 aatgacgaat atgccctttg aatcgatcga tcaagttgat gcagtagatt cgaaaagact
    73681 ttataaaagg ctgcttgcgg aaggtaagac aagagaagaa gcattggata tcattcgtga
    73741 aacaacgaga gacaacagca ggacacccat gcaatggact tcggaacaat atgctggttt
    73801 ttctacacat gaaccttggc tgatcactaa tccaaatacc aaaacgatca atgtagaaca
    73861 acaagaatat gaaccagagt cggtcctgca attctataag aacatgatcc gcattagaca
    73921 aaccaataaa ggtctgatat acggttctta taaagaatat cttcatgaac atccacaact
    73981 ttatgtctat gaaagatatt tagaagatga acaatatctt attatggtaa acttaacaga
    74041 atcacttgct gactatgaac ttccaaaaga agcagatcag tcctggacat tactcttgtc
    74101 aaattcctct agcggagaat ttgaagctaa aggcatacta gcaccttatg aagctcggtt
    74161 atataaaaca aacaagtaaa acttcctcgt taaagttcat tagttggact ttgcgaggaa
    74221 gtttttcaga ttgctctgtc aattactcat ttcaataatt cgctctagga ccaccgatat
    74281 atttaggacg agagcgaagg gctgtcacgt gagcttgtcc aagggttttc aaacgaggtc
    74341 tgacaggtac ttggacatgt ttgatatgca taccgattga tgtgtcaccg atatcgatac
    74401 cggcttgtcc aactacgtgt tccacttcga caggatcatt gaactggtca aaagcagcaa
    74461 cagaacaagc acctccagca tgtagtgcag gaacaacaga gacaatttcg aaattttttg
    74521 cttctgccac tgttcgttct actactaatg ctcggttcaa atgttcacaa ccttggacag
    74581 ctagcgcaat ttctttagga tccaacaact cttttaacgt acggatgatc cattgaccaa
    74641 cttccgcact ggaatttttt ccaatatgtc ctccaacgac ttcgcttgtg ctgcatccta
    74701 aaacaaaaag atcacctttt ttcaagtgtg cctcagccaa tatgtcatta actatttcag
    74761 tcaattggtc ttttaattct ttttctgaca acttcatttt ctaaaacctt ctttttcaat
    74821 taatattgct tccgtgcttg aatacgttga agacttgcag ttataggaaa ggcaagtccc
    74881 attccaatca gattttggaa gatgtttcct ggtatagaag ccactccagc cggccaatca
    74941 tataaaatcc aaccggcgat accatagccg atgatcataa ctaagcttcc taataaaagc
    75001 cctaatcccc acatacgagt agaagatttg ctgaaagaac cagcaacata tccttgtaac
    75061 ccgtggatca ctaatgaaaa aactgcccac tgcggatatc ctgaaatcaa atcgatcaat
    75121 agaccactgg aagcaccaac aactaatcca cccgttggac cataaagaaa agcagcggta
    75181 tagatcccgg cctcgcataa tgtcacaaat ccattcgtag ccggtacagg gatcaaaatt
    75241 gttaatgaaa gggcaactgt caacgcaatc agcatagcat agatcgttaa ttgcttagtt
    75301 ttcatttctc attcctcctt tttgaatacc gccagaccag acacttccgg tatgatcgtt
    75361 catcagcacg ccattagaaa tacaatgggc aacaaatttt ttactttctg ctactgcttt
    75421 ggtaaaatct gcccctaaca caagattcgc tgttattgca gaagaaaagg cacaaccggc
    75481 cccgtttact gttgtagtgt cgattttttt atgagaaaat acctcataat gatcaattga
    75541 atagagaaga tccacagctt catctccagc catccttgtg ccgcctttga tcacaatgtt
    75601 ttttgttcct gaagcagtga gttctttagc gagatggatc atttctgtta acgaagaggg
    75661 aagagcttga ccagaaagta aagcagcttc tgccaaatta ggcgtaatca tcgtaacaag
    75721 tggaaaaagt tcttcgatga gctgcgaaat atacaattga ttgatcacag cttcagtttc
    75781 tttgaatgcc aaaacagggt ctaaaatgat tgggatattt tgttttgttt ttatgaagtc
    75841 tcgaacaacc atgattgctt cacttgaatt caataaccca attttgatac catctaatga
    75901 agtcatttta tcaatcgaaa ctaactgtcg tttaagcaat tccaaagata tagattccag
    75961 cataaatcgc tcattaatat ctagtgcccc tatagaagtc aaggcgctta gtccgaatag
    76021 accaaaattc tcaaaagttt ttaaatctgt ttggattcct ccaccagcaa atggatcaga
    76081 accgccaatt gtcaagattc ttttcataac attttcctcc atgaataaga gtataacgaa
    76141 attttcaaaa aagaaaaaca gccaattggc atatttttat ctcatccaat ttaaaaaaac
    76201 aaaaagaaaa gaaagaccaa aatggatctt tctttcctta aatagttagg acttttgtga
    76261 ttttaattct ttctcgattt gaagccgttg cactttcatt gtagctgttc gcgggattgc
    76321 atcaaaatca cggatgatag ggacgttcaa gcgaggaagt tcatggactt gctcccacca
    76381 tcgattccaa tccatttctt tatcaggagc taaagcaata atcggttgtg gagaatgatt
    76441 tttatccctt acaatcacta cttctgccaa aaaatctaac gaatctaata aaaagtcttc
    76501 aatagctaat gtactattga tcgtttcgat caaatccact tgccgatctt tcaaaaatag
    76561 gtggccatgc ttatccataa aaccgtaatc tccgctatcc caccaatcgc cataaacatt
    76621 ttcctggaac cgtgcatctt ccttgtaata agtcaaagcc cgtcctttag acagtaattg
    76681 tatatgacca tctgtgtttt caggtaggac attcccaact gaatctgtaa tccgagcgct
    76741 tgtcatgtct tccagtccaa cgcccatatc tcttgcatca cttgttttca aactctctag
    76801 tgtatgagcc ttaagaatca ttggtccgca ttcactttgg ccatatactt gaagaaatac
    76861 cgcatcctgt gccatcgacg ttcgcaaaaa tgtcttcatt gtctggttgt ttatagcatc
    76921 aaaagtggag tgatagtatc ggatacccga aaaagcttct ggatgctcct tagcagtaaa
    76981 acgccactga acaaagttat tcggatgggt ctctagtgca attggccggt gagcttccaa
    77041 catatgaaca acttttgaac tttgtgcgtt tgctaaaggc atcataggaa atcccatgga
    77101 catcaaagaa gagataccaa tattgaatct ggaatgcact ggagagatgt gaaaagcgat
    77161 taatttcttt tccgaaattt ttgtgaaaac tgttttttgc catttcgtcc gccatcccat
    77221 agaatgagca gaatgacaaa taagtttagg gataccagtt gtaccagaag tatgggtcat
    77281 ataagaaatt tcatttttgt ctaaaaatga ttgagaaaca gacaaagcag gttgttccat
    77341 taaataaaga atagg
//
LOCUS       DAFEKH010000006        72172 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.006, whole genome shotgun sequence.
ACCESSION   DAFEKH010000006
VERSION     DAFEKH010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 72172)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72172)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72172
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.006"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..90)
                     /locus_tag="LP386_000466"
     rRNA            complement(<1..90)
                     /locus_tag="LP386_000466"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            831..1520
                     /locus_tag="LP386_000467"
     CDS             831..1520
                     /locus_tag="LP386_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1917729.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1507..2715
                     /locus_tag="LP386_000468"
     CDS             1507..2715
                     /locus_tag="LP386_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL1917730.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            3009..4280
                     /gene="serS"
                     /locus_tag="LP386_000469"
     CDS             3009..4280
                     /gene="serS"
                     /locus_tag="LP386_000469"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBL1917731.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4828..6312)
                     /gene="guaB"
                     /locus_tag="LP386_000470"
     CDS             complement(4828..6312)
                     /gene="guaB"
                     /locus_tag="LP386_000470"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HBL1917732.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6817..7512)
                     /locus_tag="LP386_000471"
     CDS             complement(6817..7512)
                     /locus_tag="LP386_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HBL1917733.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7602..8702)
                     /gene="ychF"
                     /locus_tag="LP386_000472"
     CDS             complement(7602..8702)
                     /gene="ychF"
                     /locus_tag="LP386_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HBL1917734.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8711..8902)
                     /locus_tag="LP386_000473"
     CDS             complement(8711..8902)
                     /locus_tag="LP386_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HBL1917735.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8923..9813)
                     /locus_tag="LP386_000474"
     CDS             complement(8923..9813)
                     /locus_tag="LP386_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBL1917736.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9800..10567)
                     /locus_tag="LP386_000475"
     CDS             complement(9800..10567)
                     /locus_tag="LP386_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBL1917737.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10579..11292)
                     /gene="rsmG"
                     /locus_tag="LP386_000476"
     CDS             complement(10579..11292)
                     /gene="rsmG"
                     /locus_tag="LP386_000476"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HBL1917738.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11524..13425)
                     /gene="mnmG"
                     /locus_tag="LP386_000477"
     CDS             complement(11524..13425)
                     /gene="mnmG"
                     /locus_tag="LP386_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HBL1917739.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13442..14839)
                     /gene="mnmE"
                     /locus_tag="LP386_000478"
     CDS             complement(13442..14839)
                     /gene="mnmE"
                     /locus_tag="LP386_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HBL1917740.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            15138..15521
                     /locus_tag="LP386_000479"
     CDS             15138..15521
                     /locus_tag="LP386_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917741.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15689..16447)
                     /locus_tag="LP386_000480"
     CDS             complement(15689..16447)
                     /locus_tag="LP386_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HBL1917742.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16465..17283)
                     /locus_tag="LP386_000481"
     CDS             complement(16465..17283)
                     /locus_tag="LP386_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBL1917743.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17280..17636)
                     /gene="rnpA"
                     /locus_tag="LP386_000482"
     CDS             complement(17280..17636)
                     /gene="rnpA"
                     /locus_tag="LP386_000482"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HBL1917744.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17754..17888)
                     /gene="rpmH"
                     /locus_tag="LP386_000483"
     CDS             complement(17754..17888)
                     /gene="rpmH"
                     /locus_tag="LP386_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HBL1917745.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18411..19745
                     /gene="dnaA"
                     /locus_tag="LP386_000484"
     CDS             18411..19745
                     /gene="dnaA"
                     /locus_tag="LP386_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HBL1917746.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19943..21073
                     /gene="dnaN"
                     /locus_tag="LP386_000485"
     CDS             19943..21073
                     /gene="dnaN"
                     /locus_tag="LP386_000485"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HBL1917747.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21302..21544
                     /gene="yaaA"
                     /locus_tag="LP386_000486"
     CDS             21302..21544
                     /gene="yaaA"
                     /locus_tag="LP386_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HBL1917748.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21531..22655
                     /gene="recF"
                     /locus_tag="LP386_000487"
     CDS             21531..22655
                     /gene="recF"
                     /locus_tag="LP386_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HBL1917749.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQTRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22652..24598
                     /gene="gyrB"
                     /locus_tag="LP386_000488"
     CDS             22652..24598
                     /gene="gyrB"
                     /locus_tag="LP386_000488"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HBL1917750.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24618..27089
                     /gene="gyrA"
                     /locus_tag="LP386_000489"
     CDS             24618..27089
                     /gene="gyrA"
                     /locus_tag="LP386_000489"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HBL1917751.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27325..27624
                     /locus_tag="LP386_000490"
     CDS             27325..27624
                     /locus_tag="LP386_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HBL1917752.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27674..28186
                     /gene="ssb"
                     /locus_tag="LP386_000491"
     CDS             27674..28186
                     /gene="ssb"
                     /locus_tag="LP386_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBL1917753.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            28212..28448
                     /locus_tag="LP386_000492"
     CDS             28212..28448
                     /locus_tag="LP386_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HBL1917754.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28591..30564
                     /locus_tag="LP386_000493"
     CDS             28591..30564
                     /locus_tag="LP386_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HBL1917755.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30570..31022
                     /gene="rplI"
                     /locus_tag="LP386_000494"
     CDS             30570..31022
                     /gene="rplI"
                     /locus_tag="LP386_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HBL1917756.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31296..32663
                     /gene="dnaB"
                     /locus_tag="LP386_000495"
     CDS             31296..32663
                     /gene="dnaB"
                     /locus_tag="LP386_000495"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HBL1917757.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33443..34735
                     /locus_tag="LP386_000496"
     CDS             33443..34735
                     /locus_tag="LP386_000496"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HBL1917758.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
     gene            35471..36334
                     /locus_tag="LP386_000497"
     CDS             35471..36334
                     /locus_tag="LP386_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBL1917759.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(36463..38085)
                     /locus_tag="LP386_000498"
     CDS             complement(36463..38085)
                     /locus_tag="LP386_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1917760.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            38334..38855
                     /locus_tag="LP386_000499"
     CDS             38334..38855
                     /locus_tag="LP386_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBL1917761.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(39041..40771)
                     /gene="spxB"
                     /locus_tag="LP386_000500"
     CDS             complement(39041..40771)
                     /gene="spxB"
                     /locus_tag="LP386_000500"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HBL1917762.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            40936..41754
                     /locus_tag="LP386_000501"
     CDS             40936..41754
                     /locus_tag="LP386_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HBL1917763.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(41857..42054)
                     /locus_tag="LP386_000502"
     CDS             complement(41857..42054)
                     /locus_tag="LP386_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917764.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            42223..42801
                     /locus_tag="LP386_000503"
     CDS             42223..42801
                     /locus_tag="LP386_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBL1917765.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            42896..43033
                     /locus_tag="LP386_000504"
     CDS             42896..43033
                     /locus_tag="LP386_000504"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917766.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(43846..44349)
                     /locus_tag="LP386_000505"
     CDS             complement(43846..44349)
                     /locus_tag="LP386_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBL1917767.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            44708..45733
                     /locus_tag="LP386_000506"
     CDS             44708..45733
                     /locus_tag="LP386_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBL1917768.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            46080..46958
                     /locus_tag="LP386_000507"
     CDS             46080..46958
                     /locus_tag="LP386_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
                     /protein_id="HBL1917769.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            47434..47550
                     /locus_tag="LP386_000508"
     CDS             47434..47550
                     /locus_tag="LP386_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBL1917770.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            48478..48816
                     /locus_tag="LP386_000509"
     CDS             48478..48816
                     /locus_tag="LP386_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917771.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            48910..49140
                     /locus_tag="LP386_000510"
     CDS             48910..49140
                     /locus_tag="LP386_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917772.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            49540..49911
                     /locus_tag="LP386_000511"
     CDS             49540..49911
                     /locus_tag="LP386_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HBL1917773.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(50185..50877)
                     /locus_tag="LP386_000512"
     CDS             complement(50185..50877)
                     /locus_tag="LP386_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBL1917774.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(50880..51665)
                     /locus_tag="LP386_000513"
     CDS             complement(50880..51665)
                     /locus_tag="LP386_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBL1917775.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            51902..53302
                     /gene="lacG"
                     /locus_tag="LP386_000514"
     CDS             51902..53302
                     /gene="lacG"
                     /locus_tag="LP386_000514"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HBL1917776.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            53327..53644
                     /locus_tag="LP386_000515"
     CDS             53327..53644
                     /locus_tag="LP386_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBL1917777.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            53657..55330
                     /locus_tag="LP386_000516"
     CDS             53657..55330
                     /locus_tag="LP386_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HBL1917778.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            55344..56975
                     /locus_tag="LP386_000517"
     CDS             55344..56975
                     /locus_tag="LP386_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HBL1917779.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            57847..59037
                     /locus_tag="LP386_000518"
     CDS             57847..59037
                     /locus_tag="LP386_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISLgar5 family transposase"
                     /protein_id="HBL1917780.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHYYTPQTMSNITKSFTEEVTAFNGRELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILLDLQERG
                     LKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKEVALEARGTFAEKWKTSYPKVVESILSNDHLLTFYDFPLAIRKSIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLSQ
                     LIEN"
     gene            59171..61360
                     /locus_tag="LP386_000519"
     CDS             59171..61360
                     /locus_tag="LP386_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL1917781.1"
                     /translation="MFISTLQIRNFRNYESEIFRFDNETNTIIGENDSGKTNALTALR
                     ILLDDSYYYSSKTLKESDFFHGIQNGWQGHWIIISATFEGISEEEFDNEICASISLNS
                     ESQTILEELISNADKGVGSISLFIRPNKAIRKQLFDISTELDSHQFNEFRNSIRLSDY
                     EFYYTSKSNLNFCINENYDKLVGRLNDNIASNPEEDDEALLGSRIDMSDIFKHISVVY
                     VDALRDVLREMKNNRNPVKRIMETIESKISSDNVESLKTIIQQLNETITSVPEIRKIG
                     ENINRQLNSIIGSVYSPNLLLSSTMSDDMGSLAKFLSMKPEQNIDLDLLGLGHLNMIY
                     LALKIVEFEACRSRELLNIMLIEEPEAHIHHHIQKTLFEGLNLQKNYTQILMTTHSVH
                     LAEVSEISRMNVLKSFNGKSIVMNPANNLNSFAKEKLKKNNLNLINAVERYLDVKRNG
                     LLFSKGVILVEGDAEEILIPQIVKKLFGINLDELGIGLINVGSTSFEYIASLFDDDRI
                     QRKCAIVTDLDEQAIPSEHRLYKSTAQEKGQARKEKLSSLFNENNWVNCFYANTTFEI
                     EFLDVNKENILTYVSPIIDDAFKDKKTITAYKEEIQSEQYLERNLAMLKLANHVGKGW
                     FAIELGEKIDFLIKIPKYILNAIAFACQEIVDLSIYKKILLHTIDLYEETTELSALSA
                     SLKTSDTADLNIAIISLLEYFGKDEDVVYLINQIENYTKILYAEVSK"
     gene            61357..63150
                     /locus_tag="LP386_000520"
     CDS             61357..63150
                     /locus_tag="LP386_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBL1917782.1"
                     /translation="MTNIFEKIVNDLNLEQKDVVESEDNLYVNACPGSGKTRVLTRKI
                     AYQAIKHDGSLKRIIAITYTNRAAEEIKERLSLLSIDDDINIWVGTIHQFCLEFIIYP
                     FKMNLSRVSKGFTIIDDYTQRAYVSQINNMLNLNLKTYELNKIDLSLSHDFKINEVQY
                     TQVSEMYHTMLEKNKEIDFDMILLVAYKILTVNSNVARNIASNIRAIYVDEFQDTREL
                     QYNVIAKLLQNNPQIQSMFVGDIDQAIYGSLDGIAKSVEELEMLTSHTFQSKTLHGCY
                     RSNQRLVDFYSNFQSCPYEIESRGNNKNDRGFISYDCKVTKEDLPNIIKNIIKEKIES
                     GIHEKDICVLAPQHYPLFSLGEYLKKELPYCNFDAINISPIKVNNHSLFFKLAILYFT
                     ESGEKVRRRKLIANDILIILKNEFGIEVKDYFIDLDLLQLINSVKRMYSGDDNGVDLY
                     KFVTKHIFVNLNIDEKNYPSIFKHYLFFINEVEDRIKNNSLSSSVSSFKKMFKSRDGI
                     TLTTAHKVKGNEYDTVIAINLLNGKIPHWNEIFNVSDKGISSARKLLYVICSRAKNNL
                     FLFSEVGYFTSKGDLLYPTQLLDKIEFDYNI"
     gene            63350..63664
                     /locus_tag="LP386_000521"
     CDS             63350..63664
                     /locus_tag="LP386_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBL1917783.1"
                     /translation="MELKYVIPNMEKTFGQLEYAGEGNIEQRRINGRPTILSRSYNLY
                     STIQRADDIVVILPSEAGEKHFESDEKVKLINPHITAEGYKIGNRGFTNYIMHADDMV
                     KA"
     gene            63685..64062
                     /locus_tag="LP386_000522"
     CDS             63685..64062
                     /locus_tag="LP386_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBL1917784.1"
                     /translation="MRLAEGIVIEKDQTFGTLKFSALRREVRIQNEDGTVSEEIKERT
                     YDLKSKGQGRMIQVSIPASVPLKEFDYNAEVELINPVADTVATATFRGADVDWYVKAD
                     DLVLKGQTKPHQKYKKEASESEK"
     gene            64072..64845
                     /locus_tag="LP386_000523"
     CDS             64072..64845
                     /locus_tag="LP386_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917785.1"
                     /translation="MTNTPLILKEIPKDEAISFIRQYHYSKILPRLCKYFLGIFSEEK
                     LLGVVELGWGTQPLQTIRKLFPDSSLQTTDYLEIGKMCFLPEMNQTNYFGSQALSALI
                     KWLKEHTDCHFLYTLADGIEGKCGYVYQASNFFYCGYFKTSVYRDKQSWEKIHPRSAR
                     LLLEENARFEQVEKKHWLSQAFCEYKGIEKINGRMFRYLYPLTKEAKKLLGHTLYRRH
                     YYPKEKNLRFEKRIAYQKYEAISQPTFDKQARIYNTQLF"
     gene            64867..66270
                     /locus_tag="LP386_000524"
     CDS             64867..66270
                     /locus_tag="LP386_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBL1917786.1"
                     /translation="MPLLHDRGERIKANDKHLVYHFVLISLLVVFLVVLLPFHWRALQ
                     SVNWQAVQLDTFFYQLHTPYFWSSILTALFVCGLISWLYYHYRIDSIKQLEHRQKLAR
                     MILENHWYEAEETQSEGFFKDLPSKKTKQRIRHFPKIYYRMKDGLIHIHVEITLGKYQ
                     DQLLHLENKLETGLYCELVEKTLKDSYVEYVLLYDTIGNRIGIEDVVAQDGRVKLMES
                     VYWEFDSLPHMLIAGGTGSGKSYFILTLIESLLHTNAKLYILDPKNADLADLGAVMNN
                     VYYRKEDMLACINQFYEDMIDRSETMKQHPNYKTGENYAYLGLSANFLIFDEYVAMMD
                     MLGRESTTVIHKLKQIVMLGRQAGFFLILACQRPDAKYFSDGIRDNFNFRVALGRMSE
                     MGFGMMFGSDTQKQFFLKPIKGRGYVDTGKSVISEFYTPLVPKRYDFLGEIGKVIQKK
                     QSEPVPHEVKGTGSDLL"
     gene            66452..67636
                     /locus_tag="LP386_000525"
     CDS             66452..67636
                     /locus_tag="LP386_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBL1917787.1"
                     /translation="MENEKIWIKELKEKRLAYGVSQNKLAVASHITRPYLSDIETGKA
                     VPTQQVKEDLLNALERFNPDNPLEMLFDYVRIRFPTNDVAQIIGEVLRLNMDYMLHED
                     FGYYSYPEHYRFGDIVVLVSHDVSKGVLLELKGKGCRQFENFLLAQHRSWYDFFQDCM
                     EHKGIFKRLDLAINDKTGILNIPDLAKKCKQEECISVFRSFKNYRSGELVHRDEKPYM
                     GNTLYIGSLKSEVYFCIYEKDYEQYVKNDVPLEDAEVKNRFEIRLKNDRATQAMKDLL
                     AHQQAEKTAFEIINRYIRFADKDDTKRRSDWKTNERWEWFIGKNRGALRLTTQPEPYS
                     FERTLNWLHHQVAPTLKIASILDVLNGTTIISTMIQEAKLTEKHEKLIEQQHLAMEDL
                     IT"
     gene            67633..67923
                     /locus_tag="LP386_000526"
     CDS             67633..67923
                     /locus_tag="LP386_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917788.1"
                     /translation="MSLLTKELKKLGFQCGIEFQAYIQNTGKYTSLIIEGKRQAGDTI
                     YTYDFYKVRFYNNYTNRVTVYGEHLTPFQLLRRVKSYIYYREKYLKERRTIT"
     gene            67920..68141
                     /locus_tag="LP386_000527"
     CDS             67920..68141
                     /locus_tag="LP386_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917789.1"
                     /translation="MNFGQNLYNWFLDNAQSLVLLAIVVIGLFLGFKREFSKLIGFLI
                     IALIAVGLVFNAAGVKDVLLNLFNRIIGA"
     gene            68183..68962
                     /locus_tag="LP386_000528"
     CDS             68183..68962
                     /locus_tag="LP386_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HBL1917790.1"
                     /translation="MKGFMNMFTNDQFKSLLIKTLERKSSSNYYEGGNEIVSKMKISE
                     VTLDETDDFTYYKGYKKGWNTLCTYLKIRVPFDDLDFFESHKDLITQTASSIYDKQGD
                     NVLVDTILVPLPENYEVINFSQLKISDVVSQAIEDAESFMSNGEYQRAFDRVHTAFHG
                     YLIEILKKYEITVPRDENLSKLYSRIQQLIEKEIQPTELADIVKTTIRSSNGMISSLN
                     EARNRHSLAHPNTNIIGKREAKLIIGISSTVTDYISGYLDK"
     gene            69029..69523
                     /locus_tag="LP386_000529"
     CDS             69029..69523
                     /locus_tag="LP386_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000870467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBL1917791.1"
                     /translation="MKVYVANLGRYNEGELVGAWFTPPIDEEEMAERIGLNEDYEEYA
                     IHDFELPFDVDEYTPISEINRLCEAIQEIEGTPIYNELKEIQGMWFSSLEELLENKED
                     IHCYSDCDSMEDVARYYVEETGQLGEVPSNLQNYIDYQSLGRDMEIEGNYLVTSHGVF
                     EYCQ"
     gene            69579..70217
                     /locus_tag="LP386_000530"
     CDS             69579..70217
                     /locus_tag="LP386_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917792.1"
                     /translation="MVNVFENLKLLKLDMKDKGWVIDSFYFRYKQQNYIVLVKLFEKE
                     EKVPEYALLKLEFLKENDFSDMLAVYANSVKLYTDTKTIREYFGIEYSSNLGDVLFQF
                     SQTLARFIPTEVSEKKNEDQKEAMCFSLSQSDSEDPRKKYCFSVRRNPLKGNGELGKR
                     SPFNDNKTRLYRPSLYERLGSDTNLSFRYSMNPDDEETDEGIIAKWTKNKIE"
     gene            70289..70684
                     /locus_tag="LP386_000531"
     CDS             70289..70684
                     /locus_tag="LP386_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL1917793.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDLQLPFPITFTQMTWFIVSLFVV
                     ILFGSLPPLSLIDGALLKYLGIPIVLTGFMCQKTFDGKKPYGFLKSIITYALRPKVTY
                     AGKQIRLKKETMNESITIVRSEQLDGISD"
     gene            70668..>72172
                     /locus_tag="LP386_000532"
     CDS             70668..>72172
                     /locus_tag="LP386_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL1917794.1"
                     /translation="MAYPIKYMEDNLVFNHDGEVFAYYELIPYNYSFLSSDEKIQVHD
                     NFCQLIAQNRDGKIHALQLATESSIRATQEQSKKEITGRLKEIAYEKIDEQTEALISM
                     IGDNQVDYRFFIGFKLYLNEQEVSVKNVGKEIQKAFAEFFHGVNHKLMGDFVSMPMAE
                     IERFSKMEQLLESKLSRRFQIRKLEKDDFGYIIEHLYGQTGVPFDDYDYHLPKRYEDK
                     KVLVKKYDILKPTRCLIEENQRYLRIEQEDTTTYVAYFTINSIVGELDFPNSEIFYYQ
                     QQQFTFPVDTSMNVEIVANKKALSTVRNKKKELKDLDSHAWESDNETSTNVVDALESV
                     DELESNLDQTKESMYKLSYVVRVSAKNLDELKQRCDEVKDFYDDLSIKLVRPFGDMLG
                     LHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQMIGENSGIYVGYNLDTGRNIYLQP
                     SLASQGIKGSVTNALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKA"
BASE COUNT        22812 a        12911 c        14216 g        22233 t
ORIGIN      
        1 caagctccgg tggaaaaaga agcgttcgac ttgcatgtat taggcacgcc gccagcgttc
       61 gtcctgagcc aggatcaaac tctcataaaa agttcgaaca atcttgcgat tgttaagctc
      121 aatttgtttg ctagcatatt gcttgcttgt taaaaatgtt tgttgtcttg aattgaatca
      181 agacgcccta cacatttggt ttgtcttact ttgttcagtt ttcaaaggtc tacttcatca
      241 ggagtgtttc ccgattcgtt tttggctgcc gtagcaactt ttatatcata tcagagagac
      301 aagtaattgt caactctttt ttaaaagttt tttcgatttc gtttttcgaa atcttccagc
      361 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      421 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcat
      481 ttccaacatg tcaacaactt attttttatt atttaataag ttattggtgt tcttttgaac
      541 aaataataat atatcaacat cacatgtgaa agtcaataag aaaatgctta tttatcaaca
      601 tttctagctt acatgatcat tggttagttc tggtcctttt tcgttcgtct ttataactcc
      661 gagagacgta aaatcctttt gttttcagtt taatgttcat gttcttgtct tattcacacc
      721 aactagatgt ctcaccttct aaaattttcc ttaacaaagt gctgctttta tctatttctg
      781 cttttttttg ctagaataat agtaacaata tgactctgga ggatttattt atgaaaattt
      841 tgattgctga cgatgataaa gaaatcgttg aattattaag tatctatgtt cacaatgagg
      901 ggtatgaagc agtaaaggct tatgatggga aagaagcatt atctaaaatc agaacaatcc
      961 ctgatattga attacttatt ttagatatca tgatgcctga gatggatggg atgcaagtag
     1021 tgaaagagct acgaaaagaa tcccaaatac caatcattat gctgacagca aaaactactg
     1081 atatggataa gatcaaagga ctggtcgctg gtgcagatga ttatgtgacc aagccattta
     1141 atccgttaga agtaatggct agagtaaagt ctttattacg gcgtacaaaa atgcagattg
     1201 ccccagatca gcctgatgta ttagaagtaa atgcattaat catcaataaa gactctcatg
     1261 aagttaaaac aatcgatggg aaagaaatcc agttaacagc tttggaattc ggtatcctct
     1321 acttgcttgc tagtcatcct aatcgagtat ttagcgcgga tgaaattttt gagcgtgttt
     1381 ggaaacaaga aagtattgtc tctgctaaaa ctgtcatggt tcacgttagt catttaagag
     1441 ataagattga agaagcaact ggtggtgaaa aagtcattca aaccgtttgg ggagtgggct
     1501 ataaaattga cgcaagatag taaacgagca actgaaaaac gccgtcggat caatttgact
     1561 tcaaaagaaa tcagcgaatt gttagcggaa ggaatcatca cgattatcct tttgcttcta
     1621 ttaaatgttt ctattctggt tgttatcagt tcggtgatca acagttcacc ttctttgacg
     1681 aatgcgattt gggattcaaa gaatattttt gcagaacgat tgaacactga tttgttctgg
     1741 aacggccgga attttattat tccctttttc tttctattag atattggtgt tttgtattgg
     1801 cgcttgattc gaagatatcg ccaaatgcaa ttgcggcata tcatcagcga acttcactac
     1861 atcgcaaacg gaaattatga tcatcgtatc ccttttgaac tgagtggtga cttaagccga
     1921 gtggtaacaa gtatcaatgg attggtggat agtaccgtag cagcgattga agacgaacgt
     1981 aaaatcgaaa aatcaaaaga tgaattgatc acgaatgtca gtcatgatat ccgtacccca
     2041 ctcacgtcca tcattggata cctaggactg atagaagatg gccagtatca ctcagaagaa
     2101 gatcttttaa agtatacgca tactgcttat atcaaagcaa agcagatgaa atctttagtg
     2161 gacgacttat ttgaatacac taaggtacgc cagcctgctg tcccggtgaa tttttctgcc
     2221 tttgacatga tccagttgat cgaacagtta gcagctgatt ttgagttgga agcttctaaa
     2281 aaaaatatcc aaatacttgt tcaatcaaaa gtagactccc ttatcatgga tggcgatacc
     2341 gaaaaacttg tacgtgtctt caataatctt ttgacgaatg cgttgaaata cggaaaagga
     2401 gcaacgaaga tcgtaatcga agtagaacgt atcggttcag aagttgttgc aacagtcaaa
     2461 aataacggag caatgatccc acaacaggca atcgataatc tattcgaccg tttttatcgt
     2521 gtagaagaat ctcgttcaca agcaactgga ggaactggac ttggtttagc aatcgctcaa
     2581 agcattgtgg ctttgcacgg cggatacatt tatgcaaaat cagataagca atggacttct
     2641 ttcatcatgc accttccaat caagaaaaat gaaaaattac ctattgatac acaggaagtt
     2701 attgacgaaa gctgaaatat tcgctattct tattacaatt attagaataa atgaaaaaca
     2761 cagaacccag tacactttat tctttttcag agagctgatg gcaggtgtaa atcagcaaag
     2821 gataatttgg aagttccagt tcgtttacgt gccctttcga aataagaaag gtcggttcaa
     2881 cagccgttat gtgttcaaca agtgcagctg acgctgaact tgggtggtac cgcgaatttc
     2941 agactgattc gtcccaagaa taatgggatg gatcagtctt tttttatttt caaaaaggag
     3001 gaaatcatat gttagatgta aaaatgatgc gacaaaatat tgaagaagta caagaaaaat
     3061 tgatgactcg gggcgtaaaa aaagaaacat tagctgaatt catggaacta gatgaaaatc
     3121 gtcgtaagct actagtcaaa agtgaagaat taaaaaaata tcgaaatgat gtttctgctg
     3181 agatcgccca attgaagcgt gcaaaagaag atgcttctgc taaaatcgct gaaatgaaag
     3241 aagtcggtgg caacatcaaa gcattggata ctgaaattgc tgaagtggat gaaaaattga
     3301 aacaaattgc aactactttg ccaaaccttc cccatgattc tgtgccagtt ggaacagatg
     3361 aagaggacaa tgtagaaatc cgtcgttgga gcgaaccacg tacatttgct tttgaaccaa
     3421 aaccacactg ggaaattgca gaaaatcttg atattttaga ttttgaacgt ggcgcaaaag
     3481 tagccggtag ccgttttgtc tattacaaag gattaggtgc tcgattagaa cgtgctgtct
     3541 acaacttcat gcttgatcag catatttacg aacacggcta tactgaaatg atcactcctt
     3601 atatcgtcaa cagtaaagcg atgtttggta cgggacaatt tccaaaattc aaagaagatg
     3661 ttttccaatt ggagaatact gatctaacat taatcccaac agctgaagta ccattaacta
     3721 actattataa tgatgaaatt ttagatggtg cagatttacc tatttatttc actgcactaa
     3781 gccctgcttt tcgttctgaa gccggaagtg ctggtcggga tacacgagga ctgattcgtc
     3841 ttcaccaatt caataaagta gaaatggtca aattttcgga tgtagagcat tcttacgaag
     3901 aattggaaaa aatgacagct gatgcagaag atatcttgaa aaaattgcat ttgccttatc
     3961 gtgtgatggc cttatcaact ggagacatgg gcttttctgc agctaaaact tatgacttag
     4021 aagtatggat acctgcacaa gatacttatc gtgaaatcag ttcttgttct aactgtgaag
     4081 atttccaagc acgccgcgca atgatccgtt atcgcgataa tgatggaaaa atccactata
     4141 ctcatactct gaatggttca ggacttgcag ttggccgtac agtagctgcc attttggaaa
     4201 actaccaaaa tgaagatggt tctgtcacag ttccagaagc gctcgttcct tatatgggga
     4261 atctgaaagt tattaaataa agaggctgtg aaaaagccgc ttagtttcga gtattaagaa
     4321 aaattttgtg aaaatggctt tccacatttt tgcataaatt ggacttaata ccgagaaact
     4381 ggcttttgaa caccatttat cgagaggttg tgaaatcagc gaattaacct gagtattaga
     4441 gaaaaaatgg aaaaatagtc cctcatattt taccgtttgt tgaactaata ccgagggtca
     4501 gctgattgaa caccgtttag tggagaggtc gtaagcctac cccccagctc ctagttacaa
     4561 ggacaaattc aaaaaacagc tcttcatatt ttatgaatgt tgtacttgtg attcggaggt
     4621 ggcaagggaa cactgtttat tcaaaaagag gctgggacag aagcgtttaa ctccaagaaa
     4681 taagaagaaa ttcacgaaaa ttgcttttca aatttttgtg aatttcttct tatttccgaa
     4741 ggagttgctt ctacttccgc cgtttatacg tgtttagagc gtgagacaaa agtgttcttt
     4801 acttttgtcc cacgctcttt aatgttttta agattcaact gaatagtttg gtgcttcttt
     4861 tgtgatttgt acatcatgag ggtgtgattc ttttaatcca ctgccgctca tttggataaa
     4921 ttgcgcttca tcacgtaatt gctgtagatt ggctgcccca acataaccca ttcctgaacg
     4981 caaaccgccg atcatttgga aaataatatc tgcaacactt cctttataag caacccgacc
     5041 ttcgattcct tctggtacta atttatttgc ttcattgaca ctaccttgga agtaacggtc
     5101 ttttgaacct ttttccatcg cgcctaatga gcccatacct cggtatgttt tgaatcgacg
     5161 tccttggaag atttcgaatt cacctggtga ttcatctgtc cctgccaaca tacttcctag
     5221 catcactgca tgtccgccgg cagctaatgc tttgacgatg tcaccagaat atttgatccc
     5281 tccgtctgca ataatcgctt tgccatattg acgagcaact gatgctgcat cataaatagc
     5341 tgtgagctga ggtacaccta caccggctac cacacgtgtc gtacaaatcg atcctggtcc
     5401 gataccaact tttacgacat ctacacctgc atcatataaa gcttttgtcg cttcagccgt
     5461 cgcaacgttt cctgcaatca atgttgcatc tgcaaaagtt gaacggattt cttgaatttt
     5521 tcggatcaca cctgcactat gtccatgagc tgtatcgatg atgattgcat ctgcccctgc
     5581 ttctaataaa gcattcgcac gctcaaatgt atcgcttgtt acaccaacgg ctgctgctac
     5641 aagcaatcga ccatgttcat cttttgctgc atttggaaat tcgatcactt tctcgatgtc
     5701 tttgatcgtg atcaatccgc ttaaacgacc ttcgttatct acgattggta atttttcgat
     5761 tttatgtttt tgcaaaatct tttctgcatc ttttagagag gtacctactg gggcagtcac
     5821 taagttgtct tttgtcatca catcagcaat cggcatgtga taatctgtta caaaacgcat
     5881 gtcgcggttt gtaattatcc ctaccaattt tctgttttca agtgtttcaa cgattggcac
     5941 accactgata cgatatttgc tcatcaattc ttctgcgtct gctacaagat gctgtggcgt
     6001 taagaagaac ggatcaatga ttacgccact ttcagaacgt ttgacttttc ttacttcatc
     6061 cgcttgctgg ctgatcgtca tgtttttatg gatcacacct agtccgcctt gtcttgccat
     6121 agcaatggcc atcttgctgt cggtaacagt atccatactt gcactgatga ttggaatatt
     6181 caacttaata tttttagcta attgtacgct catatccact tcgtttggta acacgtgact
     6241 ttctgctggt atcaataaga catcatcaaa agtaaatcct tttttcgtga actttgtttc
     6301 ccagttggac atttttagta ccactcctct aatttagttt atctattaaa ataattgatt
     6361 ttttcattta agtcaatgat ctacttggaa tcaagttagc tttctcatag aataccaata
     6421 taaagcgttt acatctgtgt atattaaaag agattgtaaa aaagctgtcc tgcatcaagt
     6481 aataagaaca gccaatcaaa aacagcttct catgtttttg aattggttgg gtttattacc
     6541 gcagatgcaa acttttgaac accgtttagt ggagaggctg tgaaaaagct gcttagtttc
     6601 gagtagtaag aaaaattttg tgaaaatggc tttccacatt tttgcataaa ttggacttaa
     6661 taccgagaaa ctggcttttg aacaccgttt atcgtaaaaa gggactgtga caagactttt
     6721 gtcacagtcc cttactatta tttaactatg gataaacaaa atgaggttct ttactacccc
     6781 tagatatcta gcaaaatagc tgatcttttt gctagtttat cttcttggga cggataaact
     6841 tccaataatc ccgtattttt tcttcaagta gtaacggatt gctaaagcag ttgccccgat
     6901 aatgataact actactggat ctaatactgg attgataact ggtggcaata gtgttgtcgc
     6961 agaaaacagt acgacccaaa gaagtgtcgt tccacctagg ataagcaatg tcttacccat
     7021 tcctggtttc ttgcttcgat ctgctccggg atattcatat tgatagatgt atttgtacat
     7081 catataaaag acccagccac cgattgcaga acctagaacg agtgtagaaa agccataagc
     7141 tggcgttgtt ccacgtgaaa acaatccggt aatcgcaatc atgatactta atagaccaag
     7201 caacagcaac gtattatcta accacatcaa taaaggggtg gatgaatttt ttacttctgc
     7261 tggcttattg atgattgctt ccgttctttc agagactgtc ccaaacaatt gacgggctgt
     7321 tcttccgcct ttttgttctg caactaaagt aggcagaatg tcatgaaggg cttttacttt
     7381 ttcttcttca gacaaattcg ctgcttctaa agattttttc aaatcaaaaa tgtactgttg
     7441 atttcttttg gttaattttg tttctaaact attgttttct tttacgattg ctcgtaattg
     7501 ttctggttcc attatctaat agtcctcctt agccgttcct tttctcaacg gtcgtcacaa
     7561 aagacattct accatattct acagctagtt tgatagccct tttacacatt aaagcggaat
     7621 aacattacgt cgccgtcttg tacgacataa tcttttcctt ctaatcgaac acgtccagct
     7681 tcttttgctg catgcatgtt tccgtaatga tccaagtctt caaaagagac agtttctgca
     7741 cggataaatc cgcgttcgaa atctgaatgg atgattcctg ctgcttgtgg tgctttgatt
     7801 ccttttttga atgtccaagc acgtacttct tgttccccag cagtaaagta agtagctaag
     7861 cctaacaaat cataagcagc acggatcaac tgatccaaac ctgattcttc gattcctaaa
     7921 gcttctaaaa attccgcttt gtcttcttca tctaattctg cgatttcttc ttctgcacga
     7981 gcactgacca cgatcacttc tgcattttct tctgcagcaa agttgcgcac ttcttgtaca
     8041 taatgattcg cgtctgcatc tgctacgtca tcttctgaga cattggctac ataaagaatt
     8101 ggttttgtcg tcaataaaaa tagtgattta acgatttttt gttcttcttc agtaaattcg
     8161 atcgttcggg cagattttcc ttcttccagt acaggtttga ttttatccag tacagctagt
     8221 tctgccactg catctttatc tttggtttta gcaacttttg ctacacgagt atagcgtttg
     8281 ttgatagatt ctaagtctgc taacactagt tccaagttga tcgtatcaat atcttctagt
     8341 ggatcaacac gtccttctac gtgagtaata ttatcatcat caaaacagcg aacaacgtga
     8401 caaatagcgt ctacttggcg gatatggctt aagaattgat ttcccaaacc ttctccttta
     8461 cttgcgcctt ttacgattcc agcaatatct gtaaattcaa aagtcgtcgg aacagttttt
     8521 ttcggatgta caagttctgt taagcgttgc aaacgccagt caggtacttc taccatccct
     8581 acgttggggt cgatcgtcgc aaagggatag tttgctgctt ctgctcctgc ttttgtgatc
     8641 gcattaaaca aagttgattt tcctacgttg ggcaacccaa caattccagc agtcaatgcc
     8701 ataaatttat tcactctttc tctgcatttt tttcaattac tttttttaat ttcttttcaa
     8761 aatctcgacg ggtcatcatg acgatatgtc cgcaattcat acatctgatt ttgatatctg
     8821 cgcccattcg aatgacttcc cagcgattcg tctggcaagc gtgaggtttt ttcatttcaa
     8881 cgatatcgtg caagtcgtac ataaaaatag cctccttttt gtttattctt catcaaattg
     8941 aatattcaag atatcaagaa ttcgagtcaa atctttttga gaaagatatt caatctcgat
     9001 cttacctttc ccattttttt cttggatagc tacacttgta ccaaatttat ccatcaaacg
     9061 atcttcgctt tctcggatat aatatggttt ttcctttgct agccttggga tttttttctt
     9121 ttcttttcca tcattttgat ttaactcaga aacaagctgt tccagttggc ggacagttaa
     9181 attttcagtt actgcacgat tggctaattt caagatcaat gttttatttt ttaaacctaa
     9241 cagcgtacgg gcttgtccca tagataaacg ctgatcttgt accatttcct tgacaagatc
     9301 cggtaaagaa agcaagcgca aataattggc gatataaggt ctgctctttc ctaaacgact
     9361 agctacttct gcttgtgtta gtttcaggtt tttcatcagc atctcatatg cttctgcttc
     9421 ttctaacgga ttcagatctt ctcgctgcaa gttttccagc actgctactt gcatcatcgc
     9481 ttcttcgtca aagtctctaa cgatagcagg gatcgtttct ttttcagcta gtttggacgc
     9541 tcgaaaacgt cgctcccctg caataatctc atatcctttt actgcggaac ggcgtacgat
     9601 gatgggttga aagacacctg attgttcaat agaattagct agttcctgca aagatacttc
     9661 ttcaaatgtt ttacggggct gatacggatt tggtcgcagc tcattcaatg gtagctggac
     9721 aacggtatca tcttttacat ccaccgtctc taagttttct aaatcttgaa acagtgcatc
     9781 gattcctcgg cctaatcctt tacttttctt cacgacttac cacttccttt gccaatgctt
     9841 ggtagacttc agctcctcga gaacgtggat cgtagtcgat gatcggtttt ccatgactag
     9901 gtgcttctga taaacgaata tttcttggaa tgatcgtttc gtaaactttt tcgcggaagt
     9961 atttacgtac ttcttctacg acttcatttc ccagatttgt tcgtgcatca tacattgtca
    10021 gtaagactcc ctcgatctct aattctggat taaagtgttt ttggactaaa cgaaccgtat
    10081 tcagtaattg gcttaatcct tccaatgcgt aatactcaca ctgaacaggt atcaaaatcg
    10141 aatcacttgc tgtaaatgaa ttgattgtca gatggccaag agaaggcggg caatcgatca
    10201 aaatataatc atactgactg cttacttctg ctaaagatcc ttttaatctt gattctcttg
    10261 ccatcattga cgtcaattcg atctctgctc ctgctaattg gagagtcgca ggcacaatac
    10321 tcaaattttc gtgttcagtg atcaaagttg cctcatcaat tggcaattca ttgactagaa
    10381 catcatagat gtctcttgtc acatcaggtt ttctgatccc gacaccactg gtagcatttc
    10441 cttgtgcatc catatccact agcaatactt ttttgccaag gctagcaaga caagcaccta
    10501 gattcaccgt cgtcgttgtt ttgccgacgc cacctttttg gttcgcaaca gatattattt
    10561 gtgccatctc ttctcctcct atttgattgg ctgcttatta ggcagtccgg gctttcttgg
    10621 gtatttcttt ggggttggtt tctttttttg aataacgatg atatgccgtt gatcagagac
    10681 attcggcaag gtaaccgcct cttctttgag gaatttacca cctaataaag caatcgcttg
    10741 ttttgcttct gtcaattcct cttcactttt tgctgctttc aatgcataaa aatagccttc
    10801 ttgtttagcc aagggcaaac acaattccgc taacacattc aaacgagcaa ccgcacgagc
    10861 agtgacaagg tcaaatgatg cacgaaagtg aggattttgc ccaaatgttt ctgcccggtc
    10921 atgatataag gaagcatcga ttcctaataa tcgggttaac tcagataaga aggttattcg
    10981 tttattcaga gaatcaacga tcgttatctg cagttctgga aaggcaattt ttaaaggtat
    11041 gctaggaaac cctgcccccg aaccaacatc gcataaagat aaaggttgcg taaagtctac
    11101 ttcaaatgct aatgtaagtg aatcgtaaaa atgcttcaga tatacgtctt tttcatccgt
    11161 aatagctgta aggttcatct tttcgttcca ttcgactaat gtccgataat aaatagcgaa
    11221 ttgattcatt tgatgatcgg taagctctat ccctttttct gccaaggatt ggcgaaattc
    11281 ttctggtatc ataaatattc ctttcattgt gaaacagcaa ttgtttcaca gattctctcc
    11341 ctactttaac gcaaaatctc tagacatgca atccttccat atggattctt aaaaatttga
    11401 aaagtaagaa aagccgatag actttttctt tctagtatga ctcataaaat atacacagaa
    11461 gagagaacta gctttgagca atttctgcaa aaactagttc tctcttctat ttattattac
    11521 gtattacgct ggttcactga ctttcgcaat cttcccttgt tcgatataga ccattaggat
    11581 acttaggtct gcagggttta cgccactgat tcggctagct tgggcaattg tttctggttg
    11641 gattttctgc aatttttgtt ttgcttctgt tgctaatccg ttgattgctg cgtagtcgat
    11701 gttttctgga atctttttcg cttccatgcg ttttaatttt tctacttttt ccatggcttt
    11761 tttgatgtag ccttcatatt tgatttggat ttctacttgt tcgatttctt ttcgtgtcaa
    11821 ttcttcattt tctggaataa accgtagaag ttctgcataa gtaatctcag gacgtcttaa
    11881 aaagtcgctt gctagtacac catcttttaa tggtgccgca ttaatcgttg ctaaaaagtc
    11941 ttggacttct tctgttggtt tgattcgtac attcatcaaa cgtttgattt cttgttcaac
    12001 tgcttctttt ttcttcaaat aattcttgta ttgatcttct tttactaagc ctacacggtg
    12061 acccatttct gttaatcgca aatctgcatt atcatgacgt aaaagcagac ggtattcagc
    12121 acgtgaagtc agcaaacgat aaggttcgtt cgttcctttt gttaccaaat catcgatcat
    12181 gacaccgatg taaccgtcac ttcgtttgat cactaaaggt tcttttccct gaactttcaa
    12241 agctgcattg ataccggcaa tcagcccttg tccagccgct tcttcataac cgcttgtacc
    12301 atttgtttgt ccagctgtat aaagattttc aacgacttta gtttctaatg tcggacggag
    12361 ctggtgtggc tctactacgt catattcgat agcatatcct gtacgcatca tttctacttt
    12421 ttctaatcca gcaatagaat gaagcatgtt gacttgaaca tcctctggta aagaagtaga
    12481 taaaccttga acatagactt cttccgtatt taagccttct ggttccaaaa ataattgatg
    12541 acgtggtttg tctgcaaaac gcacgatctt atcttcgatg gatggacaat agcgagcgcc
    12601 taccccttca acgatccctg taaacattgg ggcacgatgt aagttgtctc gaataatttg
    12661 gtgagtcgtc tcacctgtat aggtcagcca gcaagattcc tgatctagtt tataggcact
    12721 atctggtgtg ctgaagctaa aatgattcgg ctctttgtca ccaggctgct cttctgtaac
    12781 agaatagtcg atcgtacttg attttactcg aggcggtgtt cctgttttga accgttcgat
    12841 agcaaagcca agttctttta gatgattcgc tagtccaata gaaggttgag agttattcgg
    12901 acctgatgaa tatttcaatt caccgataat gatttctccg cgaagtgctg ttccggctgt
    12961 aataacaact gctttggccc ggtagctcgc tcctgtggac gtcactactc catgacaaac
    13021 accatcttcg acgatcagtt cttcgacgat tccttgtctt agcgtcaaat ttggttcttt
    13081 ttcgatcgta tgtttcattt ctgttgaata agcatgtttg tctgcttgtg ctcgcaatgc
    13141 tcggacagct gggccttttc ctgtgttcaa catacgcatt tggatatagg ttttatcgat
    13201 attcttaccc atttctccgc ctaacgcatc gatttctcga acgacaacgc ctttagctgg
    13261 tccgcctaca gaaggattac atggcatgaa tgctaccatg tccaaattta ttgtcagtaa
    13321 taatgttttt gatcccatac gtgcagcagc aagtgcagct tctgaaccgg cgtgtcctgc
    13381 gccaacaacg atcacgtcat acgcatctgc ttcataatgt tccaatcgtt tgttcctcct
    13441 tttattttcc taaacaaaat tgactgaata attgagtgat tagctcatct tgtacactgt
    13501 cgccgacaac ttctcctaga tagtcccagc aacgcgtcat atctatttga acgagatcca
    13561 caggcattcc tgaatcaata cctgcaatga cttcttcaag tgagagggaa gctttttcta
    13621 acaacgcgat atggcgggta ttagaaacat aagtagcgtc tctttctcct gtttctccgc
    13681 tgaagaataa atcagaaata gctgattcca aacgatctag tccgtcgttt ttagctacgg
    13741 aaattgaaaa aactggttca ttttcgatca atttcttcaa tttttcttgt tccagctgtg
    13801 ctggcaaatc tgttttattt agaagaatga tccgtttcaa tccacttgtc gcttccaata
    13861 attgttcatc ttctgctgtc agtggttcgc tttggtttag aacaagtaag atcaagtctg
    13921 cttctgctaa tgcttttcgg cttctttcga ccccgatccg ttccaccaca tcttctgttt
    13981 cccgaattcc agctgtatcg attagcttga gcggtacccc ccgaacattg acatactctt
    14041 cgattacatc tcgagtcgtt cctgcaatat ccgtaacgat tgctttttct tctcttaaca
    14101 aatggtttaa caaacttgat ttgccgacat ttggccggcc gatgattgcc gtacttaacc
    14161 cttcccgcag aaccttccct tgcttggatg tagcaagtag cgcttggatt ctttgttgga
    14221 tcatctgcgc tttttcaagc aataacttcg tagtcaattc ttcgacatca tcatattctg
    14281 gataatcaat atttacttct acttgtgcta atgtctctaa aatctcttgt ctcaatgagc
    14341 ggatcaaagc agacagattg ccgtctaact gattaagagc tagtcccatt gctttgtctg
    14401 tttttgcccg aatcaaatcc atcacagctt ctgcctgtga aaggtcaaca cgaccattca
    14461 agaatgctcg ttttgtgaat tcgcctggct cagctaatct tgcaccttct cttaacaata
    14521 gctgcaaaat ttgattgact acaacgatcc caccgtgaca attgatttct actacatctt
    14581 cccgcgtaaa tgtctttggt gctctcatca cggagaccat gacttcatcg acaagctgat
    14641 tgctcttggg atcaacgata tgtccataat ggatcgtatg acttggtact tctgataatc
    14701 gtttgtttcc agattgataa actttatctg ctagttgcac agcttgatcg ccacttaaac
    14761 gaacgatact gattgcacct tctccaggtg gggtagaaat tgccgcaatc gtatcaaatt
    14821 ctaaagtaat ttcagccatt ttttcacttc ctttttcatt ttgcgcacaa aaaaagtgcc
    14881 cactccaccc tttatgcaca ataaacggtg aacttcgcac tttgactgct tgttcttgat
    14941 taaattctgg tcatagatta tcacacttgc tataaggaat caagtgttta aaacaattag
    15001 atgaagttga gcctgttctg cttccattac cttatattta attgtccttg gatgtctctt
    15061 tgcgttcttt ggtttattcg aagagaagat actgtataaa caaggcttta tctttcttaa
    15121 aaaaaacggt acactaaatg gtagcgctat ctaaactata cacttttgaa aggagaaaat
    15181 atgtgagccc gttcagatct gctgcattgg aagaagaaag tgaccctcgg atcaacgatg
    15241 tcgttttatc tacagggaat atcaaccaga aatatatcgt ccgcgatatc gtttttgttg
    15301 tggaatgctt agaagctgat ttgtttgacc catcttttcc caaagatgac cttttcttaa
    15361 caacgaagag gaaattaaag acgaaggtac ttgaatatgg tgcgaatgca gtaatcaact
    15421 gtcattttga gtatcagcaa aaaaaacgcg acggaaagta ttttctggaa ctttttgctt
    15481 atggaacagt gatccaattt atccaaacaa cgattggtta aatgaaacag acaaaaaaag
    15541 cggatcaaaa ctgaagacag tttcgatccg cttttttcta tcaaagttag tgactacttc
    15601 atcgtatact ctgataagaa tgatttctag taaaatatac ttggtttgaa aaactttgtc
    15661 aacgtgattt attcaaaaag taatggaatc aataatattt tttagcaggt tctactacta
    15721 aataacgata aggttcctca ccttccgaat gtgtttttac atgttcatct ttgcttaatg
    15781 cagcatggat ttgtttacgt tcaaatgcag gcattggttc taagaaaaca ggctgccctg
    15841 tccgttttac tttttcagcc gtgcgatcag ctaaacgctg aatgatctct tggcgctttt
    15901 cacggtaatt gcctacattg actactacag acagcttatt tcttgctaaa cgatggatga
    15961 agacttgtgc cagatattgc aatgcattca gtgtttttcc atgtttccca atcagtatgc
    16021 cttgcttttg tgtttctaaa tggaaaacaa ccatattatt tgattctctt tccattttga
    16081 caagagctgg agcatcaagc tgttttgaaa tttcagtaag ataaactgcc aattccgtta
    16141 aagctgcttc atcacctagc tcacttactt cttctgtttt ttcttcaaga atcgtttcgt
    16201 tgactacctc gatctcagct gttggttctt cttccaaaat ttcttctaca gtctgttcta
    16261 ctgtttcaga aactttttcg ctgatacttg gctggatcga aagccgtgca ttctttcgac
    16321 ccattcctag gaaacctttt tttccttctt ccagtatttc gatttcgact tggtctttgg
    16381 ccaaacccaa atcagccaga cctagttgga cagcttcgtc tattgttgca gcttcataaa
    16441 tcggcattag cattacctcc cctattattt ccgttttttc ttaggattca ttgctttctt
    16501 aagagcacgt tctctttcgc ggattctccg tgcttcttct tcacgctctt ttcgaatttt
    16561 gaaagggttg ttgatcagca gcgtttgtac aacttggaag gcattggaaa ctacccagta
    16621 taatgaaaga ccgctggcta aattgacacc catcactaaa atcattacag gcatcacgaa
    16681 attcatgatc ttcattgatg cattcgattc aatttgactc atgctagata aatacgtact
    16741 tgcaaaagta aagattgctg ctaaaatcgg caaaataaat gttggatccg cgttccctaa
    16801 gttcaaccat aagaaatgcc cttgtttcaa ctctggtaca cgtgaaatag attgccataa
    16861 cgccatcaag attggcattt gtactaataa aggaagacaa ccagcatatg gattgacgcc
    16921 attttctgca tataaacgct gctgctcttc tcttaactta ctttgtgttt ccggatctct
    16981 tgaactatat tgttgctgca gtgcttttaa tttcggttgt aattcttgcg ttttacgcat
    17041 gctctttgtt tggaaatgca tcaacggcaa taggatcacg cggatgatca gtgtaaataa
    17101 aatgatccct atccctgcat taccaaatga caacgccttg atcgcctcag caaagtaata
    17161 aacaatataa cgatcccaaa ttcctgtact ctgtgcgctg acttccccag ttccgcaacc
    17221 ggataagacg atgaccaaac taacgatacc ggccatcaaa agtaaacgtt tgtatttctt
    17281 cacttactct tttcctctct gtcgattatt tttgcaagtt ttaagacgtg gactaaattg
    17341 gagcgaacct catcataagt caaccccttc acacttggtc tagcaatcac aataaaatcc
    17401 aactccggat caatttcttc ttttatagaa taaactgctg ctcggatttt tcgtttgact
    17461 tcattgcggt ttaccgcgtt gccgaccttt tttcctacag ataaaccaac tcgaaaatga
    17521 ggctgtcccg gtttttccaa acggtaaacg acgaatttgc ggttagcaaa agaatctccc
    17581 gtatggaaca cggcttgaaa ctctcgttct ttttttactc gatacgcttt tctcattagt
    17641 tttctttcct tttctatctc tcacttacgc tcataatcat accataatta cgattgtcct
    17701 ttcatcattt ccctaaaaaa gagtataaaa aaaaccactg aaaccccagt ggcctaagct
    17761 gaaagaactt ttcttccttt gcgacgacgg ctagctaaca cacgacgtcc atttttagta
    17821 ctcatacgtt tacggaatcc gtgaactttt tgacgtttac gtttatttgg ttggtatgtt
    17881 cttttcatat attccacctc caaaatgttc ttatctattt tataaacaca gacatacttt
    17941 gatagtataa cgacaaagta gtgattttgt caatataaaa tagaagatcg attgttaaaa
    18001 cttatccaca agattatttt tttctatggg aatcctatgt ggaaaaagtt atgcacaggg
    18061 attatccaca gataataaaa ggctggtttt acacagaaaa cacacgtgta aaaaaagtaa
    18121 tccacaatca ggcgatttcc tgtgtattcc gtctcctaac tattggtata tctgtatttt
    18181 ttatccacag acgcaagagg aaatctattg gtttttacga gttttccacc tgtgcattag
    18241 tggtgtggaa aacttttttt gacaactgtg tttttctctt ttttcttttt gtcgattgtg
    18301 tggataattg taattaaaaa atttttttct tcggtttctg tggaaaacta ttgaaaaaaa
    18361 tgctaaatta gtactagtta ttcacttttt aatgaaggag gaggccttat atggtatccc
    18421 tcgatgcttt atggaatgaa ttaaaagcaa cataccaaaa ggatttatcg cctgctagct
    18481 ataatacatg gatcgaaaca gcgaaccctc gaacccttga tcaaaaccag ctcgttgttg
    18541 aggttcctag caagattcat aaagaatatt gggaaaaaaa cctggcgaca aaaatcgttg
    18601 aagtcggtta tatgttatca ggaaatgaga ttatccctcg ctttattact ggcgaagaag
    18661 cagagcaaga agaagttata gaagaaaaaa atccaaaagt tgtggcacct agtccgctaa
    18721 aaaaagccat gctgaaccct aaatatacct ttgatacgtt tgtcattggt aaaggaaacc
    18781 agatggctca tgcagcagcg ctcgttgtag cagaagatcc aggttctatt tataacccgc
    18841 tcttctttta tggaggcgtg ggacttggta agactcactt gatgcatgca attggtcatc
    18901 aaatgctgca aagtcagcct aatgccaaag taaaatatgt aagcagtgaa acttttgcta
    18961 atgatttcat caattcgatc caaaacaaaa cagcagaaga gttccgtcaa gaatatcgaa
    19021 atgttgattt actgctagtg gatgacattc aattttttgc agaaaaagaa gctacgcaag
    19081 aagagttttt ccatactttc aatgccttgt acaatgaagg gaaacaaatc gtactaacca
    19141 gtgatcggtt gccaaacgag attccgaaac tgcaagaacg ccttgtttct cgctttgcat
    19201 gggggctgtc tgttgatatt acaccgccgg atcttgaaac aagaacagcg attttacgta
    19261 aaaaagcggc ggctgaacgt ctagagatcc cagatgacac actaagctac atcgcaggac
    19321 aaattgattc taacattcgt gaattagaag gtgcgcttgt tcgagtgcaa gcttttgctg
    19381 cgatgaatag tgaagatatt tcgactagtc tagctgcaga cgcactgaaa acgttaaaat
    19441 caggaaaagg acatcctcaa ttgtcaatcc tgcagatcca agaagaagtg gcaaagtatt
    19501 atcacatcca attgaaagat ctcaaaggaa agaaacgcgt caaatctatt gttgttccta
    19561 gacaaatcgc tatgtatttg gcacgtgagc tcacagataa ttctttaccg aaaatcggag
    19621 ctgaattcgg tggcaaggat catacaacgg ttatccatgc tcatgaaaaa atccagcagc
    19681 tgatggattc tagtgtcagt atgcaaaatg aagtatcaga aatcaaaaac tttttactaa
    19741 attaatttgt cgattctatc aactgaaaat agcatgtgga taaaagaaaa aaacgttcaa
    19801 aagttataca cactttttcc acagctgttt tttcgtttct ctcttacgtt ttttgagttt
    19861 tccacagaat caacatgccc tattactttt attattcttt ttaactaata ataaataaac
    19921 aaacattcaa aggagataca tcatgaaagt tactttaaac cgagctagct ttatgcagga
    19981 attgcaaact gttcaacgag ctatttcaag caaaaccacg atccctattt tgacaggtgt
    20041 aaaaatcaca ctgacacaag aaggtttgac tttgacgggg agcaacgctg atatatcaat
    20101 tgaaactttt ttgtctgttg aaaacgaaaa agcaaatatg caaatcgaat ctactggttc
    20161 cattgtttta caagcacgtt tctttagcga aatcattcgg agacttcctg aagaaacatt
    20221 tactttagaa gttttagaaa ataaacaagt agcgatcact tctggaaaag cgaattttat
    20281 cgtaaatgga ttagatgcag ataactatcc tcatcttcct gttgtcgaaa gccataacca
    20341 gatgaaatta cctgtacacg tattgactaa actaatcaac gaaacagttt ttgctgtctc
    20401 acaacatgag agtcgtccaa tcttgacagg tgtgcatttc attttatctg ataattcttt
    20461 attagctgta gctactgatt ctcaccgtct aagtcaacgc gtgattccag tagaacaagc
    20521 ggctgatcat tttgatattg ttattcctgg aaaaagtttg atcgaattat ctcgctcatt
    20581 aacaaatgaa gaagaaatcg tcgaaatcag cattatggaa aaccaagtgt tgttcaaaac
    20641 agaaacgatg tatttctatt cccgtttgct agaaggaaac tatccagata ccaatcgttt
    20701 gattccttca agttttaata cagaggttga attttctgtt cctagctttt tagcggcgat
    20761 cgaacgggct tctttacttt ctcatgaagg ccgtaacaac atcgttcgtt tatctattcg
    20821 tccagatgcg gttgttttat acggaaattc gccagaaatc gggaaagtag aagaaagctt
    20881 gagttataca gcaagcagtg gcgatccatt agatatttct ttcaatccgg attatatgaa
    20941 agcagcgttg cgtgcatttg gagatatgag catcaaagtg aaatttatct ctgctattcg
    21001 tccatttaca ttggaaccaa cggaagatgg cgttcaattt attcagctga ttactcctgt
    21061 acgtacaaat taacaatgat tttcaatgtt cttgaaaatt taattgaaaa gaaatagaaa
    21121 aaataaaatt ttaaacagaa ggccctaaaa tctcttttaa ggctttctgt ttatttttgt
    21181 ttaaatcacc ttttttagat taaatcgtct tatatggaaa aatatatgga taaatttgtt
    21241 ttattgcgaa aaaaaaggta taatagagta tacttttaat aatgaaaatg agggatgggc
    21301 attgaaacaa caagtcattc taaatacgga attcatgacg ttgggccaaa tgttgaaaga
    21361 agtcacagtt atcggtagtg gcggacaagc aaaatggtat ttggcagaaa acactgtgtt
    21421 agtcgatggc gaaccagaaa atcgtcgtgg acgcaaactt tatcccggca tgatggttga
    21481 agttccagaa gtaggaactt tttttatggt aaaaaaagga aacgacgata atgaggctga
    21541 ataagctgta tttaaaaaat tatcgaaatt acgaagagct gaacatcgaa ttttccaaga
    21601 acctcgtcat ctttttagga gaaaatgcgc aaggaaaaac gaatcttttg gaaagtatct
    21661 acgtattagc tatgacgcga agtcatcgga caagtagtga gcaggaattg attggctgga
    21721 ctgacgatca ggcgatgatt caaggagaga tcacaaaagg ttcatccact cttccattag
    21781 aaatcttatt atctaaaaaa ggccgaaaaa ccaagatcaa ccatatcgaa cagaaaaagt
    21841 taagtactta cgtgggacaa atgaatgtca ttttatttgc accagaagat ctttctttag
    21901 taaaaggcag cccgcagacc aggcggaagt ttttagatat ggaattaggc cagatcaatc
    21961 caatctatct ttatgatctt gtccaatacc aagcaatttt gaaacaaaga aaccagtact
    22021 tgaagcaatt gaatgaaaaa aaacaaactg atttgcttta tttggatatt ttgtccgaac
    22081 aactagcagc gtttggcagc aaagtattga aagcaagagc acagttcgtc aagcgattgg
    22141 agttttgggc taattctttg catcagcaaa tcacccatca aaaagagcag ctggaaatcg
    22201 agtatctcac cgcagtcgat tctttagaaa cacatacgca agagcaaatc caagaacaat
    22261 ttctcgcact tttgaaccaa aataaaaaga aagacctttt tcggggaaca acgacagttg
    22321 gtcctcatcg tgacgatctt tcctttttta ttaatcagaa aaatgtgcag acttatggat
    22381 cgcaaggaca gcaaagaaca actgcactaa gtgtcaaatt agcagaaatc gatttgatta
    22441 aagaagagac aggggaatat ccaatccttt tgttagatga tgtgatgagc gagctggatg
    22501 ataatcgtca actccatctg ctagaaacaa tcgaaggaaa agttcaaacg ttcttaacaa
    22561 caacgacact tgaccatgta aaaaataaaa tgactgttga acctgagatt ttttatgttc
    22621 aacaagggaa actaaaagga gaagaaactg aatgacagaa gaaagaagtt tagtagaacg
    22681 cgctaaagag tatgatgcca gtcagattca agtacttgaa ggacttgaag ccgttcgtaa
    22741 acgacctggc atgtatatcg gttcgactag ttctgagggt ctgcatcacc ttgtttggga
    22801 aattgtcgat aattcgatcg atgaagtatt agcaggtttt gcaacgaaaa tccatgtgat
    22861 tattgaaaaa gacaacagta tcaccgttat tgacgacggt cgggggatac ctgtagatat
    22921 ccaggcaaaa actggacgtc ctgcagttga aacggtcttt actgttttac atgctggagg
    22981 aaaattcggc ggtggtgggt acaaagtttc tggtggactt cacggagtag gatcttctgt
    23041 tgttaacgcg ctttctacac agcttgatgt caaagtatac aaagaaggaa atgtgtacta
    23101 tcaagaatat cgtcgtggag ctgtagtgga cgacttaaag attatcgaac aaacggatcg
    23161 ccatggaaca acggttcact ttacgccaga ccctgaaatt tttacagaga caactgagtt
    23221 tgatttttca aaattggcta cccggatccg tgaacttgct ttcttgaacc gcgggatgcg
    23281 tatatcgatt gaagacaaac gagaagaaga accagtcatc aatgaatacc attatgacgg
    23341 cgggattaaa agttatgtcg aatacttgaa tgcaaacaaa accgtgattt ttccagaacc
    23401 tgtatatttg gaaggtgaac agcaagatat cgcagttgaa gtctctatgc aatatacaga
    23461 cggctaccat tccaatatca tgagttttgc caacaatatc catacgtatg aaggcggaac
    23521 acatgaatca ggattcaaga ctgctttaac tcgtgtgata aatgattatg cccgaaaaca
    23581 aaagctgatg aaagaaaatg acgacaactt gaccggtgaa gacgtgcgag aaggattgac
    23641 agctgttatt tctatcaagc atcctgaccc tcaattcgaa ggacaaacaa aaacaaaatt
    23701 gggcaattcc gaagtacgga cagtcactga tcggttattt agcgaacatt tcatgaaatt
    23761 cttgctggaa aacccaagtg tgggccgtca aattgttgaa aaaggattac tagcttccag
    23821 agctcgtcta gcagcgaaac gtgcgcgtga agtaacgaga cgtaaaggtg ctttagagat
    23881 tagtaatctg ccaggaaaat tagcggactg ctctagcaac gatcctgaaa aatgcgaatt
    23941 gttcatcgtc gaaggagatt cggccggcgg atcagctaag caaggtcgta atcgagagtt
    24001 tcaagccatc ttgcctattc gtgggaaaat cttgaatgtt gaaaaagcaa gcatggacaa
    24061 gatcttggca aatgaagaga tccggtcttt atttactgct atgggtacag ggtttggaga
    24121 agattttgat gtatcgaaag ctcgctacca caaattagtt atcatgactg atgccgatgt
    24181 cgacggcgcg catatccgta cattgctgct gactcttttt tatcgttaca tgcgtcctat
    24241 tgttgaagct ggatacgtct atattgctca gccaccttta tacggggtaa aacaagggaa
    24301 gaatattacg tatgtacaac caggaaaaaa tgcagaagaa gagttgaaac aagtcgttgc
    24361 ttcacttcct gcctcaccaa aaccaagcgt tcagcgttat aaaggacttg gagaaatgga
    24421 tgatcatcaa ctatgggaaa caactatgga cccaagcaat cggatgatgg cccgcgtcag
    24481 tgtggacgat gctattgcag cagatcagat atttgaaatg ttgatggggg atcgagtaga
    24541 accccgtcgt gcattcatcg aggaaaatgc acactatgtg aagaacttag atatttaatc
    24601 atgaaggagg aaaaagaatg agtgaagaaa tcagagaaaa catccatgat gtcaatctaa
    24661 ccagcgaaat gaaagactcc ttcatcgatt atgcgatgag tgttattgtc gcacgtgcac
    24721 ttcctgatgt cagagatggt ctgaaacccg ttcatcgccg tattttatac ggcatgaacg
    24781 aattaggtgt aacaccggat aaagcccata aaaaatctgc cagaatcgtc ggagatgtca
    24841 tgggtaaata ccatcctcat ggagactatg cgatctatga gtcaatggta cggatggcac
    24901 agccattcag ctaccgttat atgctagtgg atggtcatgg aaactttggt tctgttgacg
    24961 gtgacggtgc cgccgctatg cgttataccg aagcacggat gagcaaaatc gctacagaaa
    25021 tgctgcgtga tatcaataag aacactgttg atttccaaag caactatgat gatacagaaa
    25081 aagaaccagt tgtactacct gctcgcttcc cgaatctttt agtgaacgga acaacgggga
    25141 tcgccgtagg tatggccacg aatatcccac ctcataactt gtctgaggta gtagcggcta
    25201 tcgatttgct gatggataat cctgatgtga cgaccaatga attgatggaa gtattacctg
    25261 gaccagattt tccaacaggt ggtttggtta tgggaaaatc aggaatccga agagcgtatg
    25321 aaacaggtaa gggttctatt accgtacgtg caaaagttga gattactgag atgccaaatg
    25381 gtaaagaacg gatcatcgtg acagaattgc cttatatggt caataaagca aaattgatcg
    25441 aacggatttc tgaactgcac agagacaagc gtatcgaagg gatcacagat ttgcgggacg
    25501 aatcttcccg tgaaggtatg cggatcgtca ttgacatccg tcgtgacgcc agcgcatctg
    25561 ttatcttgaa taacttatat aaattgacat ccttgcaaaa ttcatttgga ttcaatatgt
    25621 tggcgatcga aaaaggtgtg ccgaaagttt tgagcttgaa acaaattctt gaaaactata
    25681 tcgaacatca gcgcgaagtc atcacaagac ggacagtctt tgaaaaagaa aaagcagaag
    25741 caagggcaca cattttagaa ggtttgcgta ttgctttgga tcatatcgat gaaatcattg
    25801 cgattatccg cgggtctaaa tcagatgacg aagcaaaagc gacgatgatc gaacggttcg
    25861 atttatccga tcgccagtct caagctattt tagatatgcg tttacgccga ttgaccggtt
    25921 tggaacggga aaaaatcgaa aatgaatacc aagaactctt aaaactgatt gaagatttaa
    25981 ctgacattct ggcaagacca gaacgtgtta cagaaatcat caagaatgaa ttagcagact
    26041 tgaatcaacg atttggtgat aaacgacgca cagaattact agtcggtgag gtcttaagtc
    26101 tggaagatga agatttaatc gaagaagaag aaatcgttat tacattgaca aacaatggtt
    26161 acatcaaacg tttggcaaat aatgaattca gagctcaacg aaggggtgga cgtggtgtcc
    26221 aaggaatggg tatccacaat gacgacttcg tcaaaaatct ggtttcttgt tctacccatg
    26281 atacattgtt attctttacg aataacggaa aagtgtatcg ggcaaaagga tacgaaattc
    26341 cagaatacgg gcgcacagcc aaaggaatac caattatcaa tttactaggt atcgattcga
    26401 gtgaaagcat ccaggcaatc attgcggtga cgggagaagc agaagaaggc cactatctct
    26461 tctttacgac gcgtcaaggt acagtaaaac gtacttctgt cactgctttt gctaacatcc
    26521 gaagtaatgg tctgatcgca attggtttga aagaagacga tgagctcgtc aatgtgctac
    26581 tgacagatgg tcaatctaat atcattattg gaacacataa cggctactct gtcactttca
    26641 aagaagaagc agtccgcgat atgggacgta cagcttccgg ggttagagga atacgcctgc
    26701 gtgaggaaga ttatgtcgtt ggggcagcct taatgaagga agatcaagaa gtattagtga
    26761 tcacagaaaa aggttacgga aaacggacaa aagtatcgga atatccagtg aaaggccgcg
    26821 gaggtaaagg gatcaaaacg gcgaacatca ctgaaaaaaa tggtccacta gctggattga
    26881 ccactgtttc tggagatgaa gacatcatgc tgattacaga taaaggtgtc attatccgtt
    26941 tcaacgtatc gactgtttct caaactggac gttcaacatt aggcgtacgt ttgatgaaga
    27001 tggaagctga tacgaaagtt gtcacgatgg cagcagtcga accagaagct gcagaacaaa
    27061 cagttgaaga acaaggatca gaagaatagc catcaagact aattgtgtaa gctagcaaga
    27121 atgaccgatt aaaaaatctg gttattcctg ctggcttttt tgattagttg aatttctctt
    27181 aaaatattcg aaactgttca ttctgtattg cttttgacca aaatagagtg tataatcaga
    27241 gcttgtgagt agtctaatta attagataac tctccttgct cttaggaacc taagagccga
    27301 aagtccacag ggaggtgaat atcaatggaa aacacgaaat atgaaatcat gtacattatt
    27361 cgtccaaaca ttgatgaaga agcaaaaact gctttaatcg aacgtttcga tgcaatcttg
    27421 aaagataacg gagcagaagt tatcgaatca aaagattggg aaaaacgccg tttcgcttat
    27481 gaaatgaacg gttaccgtga aggtatctat cacatcgtta aagtatcttc tccatcatca
    27541 gcaaatgctg tcaatgaatt tgaccgtctt gctaaaatca acgacgatat cattcgtcac
    27601 atgattgtta aagaagaagc ttaattgttg tttcatgtga aacaatagaa aacgatgaga
    27661 ggagatgact attttgatta ataatgttgt attagttgga cgtctgacga aagatccaga
    27721 tttgcgttac acagcaagtg gtacggcagt cgcaacattt actttggctg tgaatcgtaa
    27781 ttttacaaac caaagcggca atcgcgaggc tgattttatc aactgtgtga tttggcgcaa
    27841 atcagcagaa actttagcaa actatgctcg taaaggaaca cttttaggtg ttactggacg
    27901 tatccaaact cgttcttatg ataatcagca aggacaacgt gtatacgtga cagaagtagt
    27961 agctgacaac ttccaattgc tggaaagtcg ttctgcatct gaaaatcgcc aacaaagcgg
    28021 cggattccaa agttctggtc aatcagctgg cggatttggc ggaaacaata actctaatca
    28081 aacatctcaa tcatccaacg gtatgcctga tttcgaccgt gatacttctg acccattcgg
    28141 ctcaagttca acgatcgaca tttcagacga tgatttacca ttctaaacga atttgatagg
    28201 agggaaatag aatggcacaa caaagaagag gcggacgtaa acgtcgtaaa gtagactaca
    28261 ttgctgctaa ccatattgaa tatatcgatt ataaagatat cgaattacta aaaagattta
    28321 tttcagaacg cggtaaaatc ttgccacgtc gtgtaactgg tacaggcgct aaaaaccaac
    28381 gtaaaattac tgttgcaatc aaacgcgctc gtatcatggg cttgctacct ttcgttagcg
    28441 aagactaata aatcctagga attgaatgac tgatcctttt gatcagctat tcaattcctt
    28501 tttttctgta aaaataacct ctattcgttt agtcgctcga atgacgaaag ttatggtaaa
    28561 atcaaattag tcatatatgg gaggaaaatt atggaaaata aaaacaatca tttatccccg
    28621 aaacctctct tccttatcct gtttatatta atcgaagtat tggtagtctt aattttacca
    28681 tttcgttttg ttagcgcttc ggtcattcta ttgatgaatt tatggggtgt tcgctattgg
    28741 ttgaaaatga aacgttggct tattttaaat aaacgtgaaa aaatccagca ggcttcgact
    28801 gtagctgaaa ccaatctagc ttatgtctca gaagtcatgc ctgtaggagt gattgcttat
    28861 cagccatcaa gccaaaaaat cgaatggctc aatccattag cattgaaaat caaagatcaa
    28921 agtggattaa cagaggaaga attgctagat acttttttta ctgcaaaaga aaaaaagaaa
    28981 aaccaagtct atctagcaga taaaacattt cagtttgata tggatacagt aaagggtgtt
    29041 gtttatttta atgatattac ccaaaaccag ttgttaaaac tccatcagac gaacagtcag
    29101 ccggtgattg gtattttatc tattgataac tatgcagatg ccattgataa attggatgac
    29161 aaagagattt cttatttgaa ctctttcgtc actacactag tttctgactg gatgaatgaa
    29221 taccatgtct ttttcaaaag aatcaacgca gaacggtttt tcttcgtagc acagatgatc
    29281 gatctgaaaa agatgatgga taaaaaattt gatttgctgg atcgctttcg agcagaagct
    29341 gaaaaacaga gctcgcctat cacccttagt atggggattg cttatggctc aagaaccctc
    29401 gatgaaatcg gtggagaagc tcagaataat ttagatgttg ctttagtccg tggaggcgac
    29461 caagttgtcg tgaaagaggt aaaagaagga gcaaaacctg tttattatgg ggggaaatct
    29521 gctaagaatg tcaaacgcac gcgtgttcgt tctcgagcga tgagtaccgc tttgcgtcgg
    29581 atttttgatg aaacaggcga tgtgtttatc atggggcaca agtttccgga tatggatgct
    29641 ttaggctctg cttttggtgt cagttgtctg gcacgcttca accagaaaaa agcttacatc
    29701 gttatcaacg agaacgagat cattccagat gtagaacggt gtcttgaaga aatccataag
    29761 catcctgaat tagaaatgca actaatctct ccagaacgtg ccatagagct gaaaaaagaa
    29821 gaggacctcc tcgtgatggt ggattaccat aaaccttctc tatcgatctc tcagggccta
    29881 tatgagcaat ttgataagat tgtgatcatt gatcaccatc gtcgtgggga agagtttcca
    29941 agtaaacctc tgctgactta tatcgaatct tcagcttctt cagcttcaga gctagtttct
    30001 gagctgatcc aataccaaag cagcaaaaca aatcgcttag atcgttttga ggccacatta
    30061 ttgcttgcag ggatggttgt agatacaaat agtttcaatg tccgtacaac tgcacgaact
    30121 tttgacgttg ccagctattt aaggtcttgt ggagcagacg catccttagt acaatattta
    30181 ttgagctcgg atttagcgac atacttggag atcagcaatt tgattgctgg aagcgactat
    30241 gtgacttctg atattgttgt ggcggcaggg acagacgaaa aagagtataa tagtgttata
    30301 gcagcaaaaa cagcagatac attgctttcg atgatcaata tcaatgcagc tttcgtcatt
    30361 acaaagcgga cagacggctt gattgggatc agtgccagaa gtaccggcac gatcaacgtc
    30421 caaatcatca tggaatcctt aggtggcgga ggacacttca caaacgcagc tactcaactg
    30481 gaaaatacga cagttgagga aacaaaacag aagctatttg ctgcaatcaa agaaaatatg
    30541 aatcaaatat atgataagga gtaatccaaa tgaaagtaat ttttttacaa gatgtaaaag
    30601 gaaaaggtaa aaaaggggac atcaaagaag ttccagcagg ttatgcacaa aattatctaa
    30661 tcaaaaataa cttggcaaaa gaagcaacga aaagcagtat cagtcagtta gcaggacaaa
    30721 agaaagcaca agaaaaacac gaagctgaaa tcttggaaga agctaaaaag ttaaaagaat
    30781 tcttggaaaa agaagatact gtagtcgaat tgaaggcgaa agcaggggaa gacagccgtt
    30841 tgtttggttc gatcccttca aaacaaattg ctgaagggtt aaacaaacaa tacaaaatca
    30901 aattagataa acgaaaaatc gaattagaaa atccgatccg ttcactaggc tacacaaacg
    30961 tacctgttaa gcttcatcat gaggtgacgg ctacgatcaa agttcatgtc gtacaagaat
    31021 aacaaatctt gatagcgatg ttcagctggt aagtataacc agaaggaaaa aagacaaacc
    31081 gaaatttatc tgagaaaaca gctgcagcaa tgaaagcaaa agctgcaaat cgatttcaga
    31141 ttgatttcgg tttctttttt gggaacagca aaatagcata aagaaaacga gtataataaa
    31201 agagaactat ttttttatta cactttcggt acgaatgatg acttttctct cattttcttg
    31261 taaaatgaag caattgaaga caaggagcga tacgtatgaa tgaagtgtgg caggatcgaa
    31321 tcccaccgca aaatattgaa gctgaacaag cggttttagg ctctgttttt cttgacgcag
    31381 aaacgatcat tgatgccatg gagtacatag agccaaaaga cttttatcgt cgtggccatc
    31441 aaattatttt tgagacaatg atcgagttaa atgatcgtaa tgaagcgatt gacgtggtta
    31501 ctgtcaaaga ccggctggaa caagccaatt tgttagaaga tgccggtggt ttaagttatc
    31561 tctcagactt ggcattagca gttccgacag cagcaaatat cgtctactat gcgaaaatcg
    31621 ttgaagaaaa atcattgctg cgtacattga tccagacagc aacaggaatc gttacgaaag
    31681 gattcgagca aggagaagaa gttcaaacaa ttttagatga tgccgaacgc agtatcttgg
    31741 aggtttcgga aaaaagaaat cgaagcggct ttttatctat tgctgaagta ctgaactcca
    31801 cgattgaaaa tatcgatcga ctagctcaaa acaatgaaga aatcacaggt ctaccaactg
    31861 gctatcaagg tctggataaa atgacagcag gtttccagcc cgaagaacta atcattcttg
    31921 ctgcacgtcc agcggtaggt aaaacagcgt ttgcattgaa tattgctcaa aatgtaggaa
    31981 caaaaacaga tcgttctgtt gcgatattta gtttggaaat gggggcagaa tctcttgtaa
    32041 atcggatgct ttgtgcagaa ggttcgattg aggccagcca tttacgtaca ggtcagcttt
    32101 cggaagaaga atggtcgaat ctgatcgttg cgatggggag tctttctcga gcaaatattt
    32161 ttatcgatga tacaccaggg atcaaaatct ctgaaatccg tgcgaaatgt cggaaactag
    32221 cgcaagaaaa aggcaatcta ggcttgatat tgatcgatta tttgcagttg attgaaggta
    32281 acggtaaaga gaaccgtcaa caagaagtat cagatatctc tcgccaactg aaaaaactgg
    32341 cgaaagagct gaaagtacct gtcattgctc tttcacagtt atctcgtgga gtagaacagc
    32401 gacaagacaa acgaccagtg ctaagtgata ttcgtgaatc cggatcaatt gaacaagatg
    32461 cggacatcgt agccttcttg tatcgagatg attattatga aagagaaggc ggagatgacg
    32521 atgatggaaa cgagccaaaa aatgacaacg tcatcgaagt catcatcgag aagaaccgaa
    32581 gcggtgcacg aggaacagtt gaactactgt ttatcaaaga atacaataag ttttcgtcgc
    32641 tttcgccaag agaagaattt taaagaagag gttgtgagcc ttgagcaatc ccgagagctc
    32701 tcgtaagaag atgcaaggag taaccgcagg aacgactaga gtacttaatt taaacagatc
    32761 tccaaaggga ttgtgacaaa agtcttgtca cagtcccttt ttccgaataa acggtgttca
    32821 atcagctgac ccttggtatt agctcagcaa acgtcaaaat atgaggaact attttgacgt
    32881 ttgtttctct aatactcagg tcaaaacgct gatcttacga cctcttttcc ttaaacggtg
    32941 ttctcctgcc aactcctcgg tcacaagtca caatatcatc aaacatgaga agcagttttt
    33001 tgaaattgct ccttgtgact cagagttaaa cggcaggctc acaacctctt tcttaaacgg
    33061 tgttcaaaag cttgcatctg cggtaatacg cccaatcaaa cgaaaaatat gagaagctat
    33121 ttttgtttgg ctgttcttat tacttgatgc aggacagctt tttcacaacc tctgattcac
    33181 ggtgttccaa aagtagcttc ttcgaaaaat aagtcgaaat ttcacaaaaa tttgagaagc
    33241 aattttcgta cattccttct tatttcttga agctgaccac ttctgttaca acctcttttt
    33301 taataaccat tctaaaaaga taaagttcgt tttttaagcg tttttataaa ataaaaataa
    33361 aaatcattcg attttatttg aaatatgtat ctattattga tacaatggtt caggattaaa
    33421 taatatagaa cgaggtgttc acatgtcatc tgtagtagta gtaggtacgc aatggggcga
    33481 tgaagggaaa ggaaaaatca cagactttct cagtgaaaat gctgaagtga ttgcacggta
    33541 ccaaggtggc gacaatgcag ggcacacaat taagtttaac ggtgtgactt ataaactgca
    33601 tttgattcct tctgggattt tttataaaga caagatcagt gtgatcggaa acggcgttgt
    33661 agtcaatcct aaatcattgg ttaaagaatt agcttattta catgaaaaag gtgtagaaac
    33721 aagtaatttg cgtatttctg accgcgcgca cgtaatcttg ccttatcata tcaaattgga
    33781 ccaattacaa gaagatgcta agggcgaaaa taagattggt acaacgatta aaggaatcgg
    33841 acctgcctat atggataaag cagctcgtgt aggtatccgt attgcagact tattagataa
    33901 agaaattttt gaagaacgtc ttcgtttgaa tctagatgac aaaaaccgtc aatttgtaaa
    33961 aatgtttgat tcagaaccac ttgattttga cgatattttt gaagaatatt atgaatacgg
    34021 acaacaaatc aaacaatacg tcacagatac ttccgttatc ttgaatgatg ctttggatgc
    34081 aggcaaacgc gtgttgtttg aaggcgcaca aggtgtaatg ctggatatcg accagggaac
    34141 ttatcctttt gttacttctt ctaacccagt agccggtggg gtaacaatcg gaagcggtgt
    34201 agggccttca aaaatcaata aagttgtcgg cgtctgcaaa gcctatacgt cacgtgtcgg
    34261 tgatggacca tttccaactg aattatttga tgaaacagga gaacaaatcc gcgaagtagg
    34321 acgagaatac ggtacgacaa ctggtcgtcc gcgtcgtgta ggctggtttg attctgtagt
    34381 tatgcgccat tctaaacgag tttcaggtat taccaaccta tctttaaact cgatcgatgt
    34441 attaagtgga ttggaaacag taaaaatttg tacggcttat gaattagatg gcgaactaat
    34501 ctaccactat ccagcaagct tgaaagagtt gaaccgctgc aaaccaatct atgaagaatt
    34561 gccaggctgg tcagaagaca ttacaggatg caaaacactt gcagaactgc cagaaaacgc
    34621 acgtaactat gtacgtcgta tctcagagct tgttggtgta cgtatctcaa cattttctgt
    34681 cggacctgat agaacacaaa caaacatctt agaaagcgtc tgggcgcaaa tctaaggata
    34741 aaaacgacga ctgaatcagg acgttcttac cagagcgagt cgaagtgttt atctatacga
    34801 taataataac ttgaacactg tttattcaga ataagggact gtgacaaaaa ccgtgtcaca
    34861 gtcccttttt ccgaacaaac ggtgttcaaa agcttgcatc tacggcacta agcccaatca
    34921 gatgaaaaat atggagtgct atttttatct gattgttctt actgcttgat gcagagcagc
    34981 tttttcacaa cctctccact aaacggtgtt ctcctgccaa ctcctcggtc acaagtcaca
    35041 atattcaaca aacatgagaa gctgtttttt gaaattgttc cttgtgactc ggagctaaac
    35101 ggcaggctca caacctcttg gtaaacggtg ttcaatcagc tgaccctcgg tattagctca
    35161 aaaaacggca aaatatgagg aactattttt tccgtttttt tctctaatac tcaggtcaaa
    35221 acgctgattt cacaacctct gattcacggt gttccagaag tagcttctac ggaaataagc
    35281 cgaaatttca caaaaatttg agaagcaatt ttcgtaaatt ccttcttatt tcttgaagct
    35341 gaccacttct gtcacaacct cttattttga ttagaacttg cgaaaataaa ccggttaaag
    35401 tgtgtctagc gcaagagatt tgctataata gacgataagg gtaaaatgta acgagaaggg
    35461 gttgaaaaat gtgtatcaaa ttgtaacaga ttcttgttgt gatctgccat accatgtatt
    35521 agcaaaagaa aaagttgatt ttttatcaat gaatctccaa ttgaatgatc aagagttagt
    35581 agatgacctc ggaaagacat tcaattatga ccgctacatg aatcagctga aaaatggtgc
    35641 gatgcctacg acatcacaaa tcaatgttgg ccgatattta gaatttttcc gttcttatgc
    35701 ggaaaaacag attcctgttt tatatgtggc tttttccagt ggattaagcg gctcttacag
    35761 tagtgcgctt caagcggttg aattgctgaa ggaagaatat gaagaccctg agatctatgt
    35821 ttttgataca aaagctgcaa gtattgggga agggctttta gtattggaag ctgtaagatt
    35881 gaaaaaagaa ggtaaaagca tcgaagaaac cctagagtgg ctggaaagta attatttgaa
    35941 agtccattca tgggtaacag tagacgatct gaaatatcta gaacgaggcg gtaggatttc
    36001 caaagcaagt gctactcttg gcagtctatt gagtgtaaag cctattatta cggtggataa
    36061 agaaggaagg ctgacgaatg ttgacaaagt tcgaggaaga aacaagtcga tccagacaat
    36121 cgtcaatgag acggtaaaaa caatcgttgc accacttgat caaatcgttt atgtggctta
    36181 cgctggggat ctagagagcg cggagaaggc aaaacggctt ttggaagagc agataaagat
    36241 gaaagatgtg aagctttatc ccttaggacc aacgatcgcc agtcacacag gctatggctg
    36301 tatcgcgatt ttttcgatgg gaatcagtcg ataaaagcag taactcattc tgtaaaaaag
    36361 cccagaaatt gattgtaaca aaaacagcga ctcttaaaag atagatgagc atcctatctc
    36421 ttagaggtcg ctgttttttt attttttaag ctaaataggc cattatgccc ataactcgtt
    36481 caattgtttt tgaatatctg cattttccaa aaattcatca tatgtcgtat cagctcgatc
    36541 gatcacacct ttatccgaaa cggcaatgat gcggtttgcc aatgtttgga taaattgatg
    36601 gtcatgtgac gcaaataaga ttgagccagt aaatgccatc aagccgtcat tcaatgctgt
    36661 gattgattct aagtctaaat ggttcgttgg atcatctaat acaagtacgt tagctttcga
    36721 aagcatcatt tttgaaagca tgcaacggac tttctctcca ccagataaaa cattcactgg
    36781 tttcaatact tcttcaccag aaaacaacat tcttcctaag aagcttctta agaaggtgtt
    36841 atcatcttct tctttacttg catattgacg caaccagtct aaaatcgtta gatcagtatc
    36901 gaattctttc gttgtatcct ttggtaaata agaattactt gttgtcacac cccaacgtac
    36961 tgttccagta tctggcgtaa tttcacccat gataactttg aatagcgttg ttgttgttat
    37021 atcattttct gcgacgaaag cgaccttgtc ttctttgctc aaattaaaag atatatcatc
    37081 taaaattttc tttccatcaa tcgttacact tacattttct acctgcaata agtcgtttcc
    37141 aatctcacgt tcaggtttga atccaacgaa tggataacgt ctagaagaag gttggatatc
    37201 gtctaaagta attttttcaa gcattttttt acgtgaagtt gcttgttttg attttgatgc
    37261 attcgcacta aagcgggcaa taaattcttg gagttctttg atttgttctt cttttttggc
    37321 atttgcgttt gcttgaagtt tagccgctag ttgactagat tccaaccaaa aatcataatt
    37381 tcctacataa agtttgattt taccaaaatc tagatccgcc atatgtgtac atactttgtt
    37441 caaaaagtga cggtcatggg atacaacgat cacagtattt tcaaaattga tcaaaaattc
    37501 ttccagccaa ttgatcgatt ggatatccag accgtttgtt ggttcgtcta gcaaaagaac
    37561 atcaggttta ccaaatagtg tttgtgctaa taacactttt accttttgtc caccagttaa
    37621 ttcactcatt tgctgatggt gcaattcttc agggatgttc agaccttgca gtaaaacagc
    37681 tgcttctggt tcagcttccc atccattaag ctcagcaaat tctccttcta attcagctgc
    37741 tcgaatacca tcttcgtcag tgaaatcctc tttcatgtaa atcgcatctt tttctttcag
    37801 cacttcatac agacgcttgt gtcccatgat gactgtttca agtacagtat agtcttcata
    37861 gtcgtaatgg ttctgtttca atacggccat ccgttcatct ggtcccatag taacggaacc
    37921 tgtggaaggc tgcagatccc ctgataacac tttaaggaac gttgatttac ctgcaccatt
    37981 tgcaccaatc aagccatagc agtttccggg ggtaaattta atattcacat catcaaatag
    38041 tttgcggtct gaaaagtgca aactcacatc atttacagta atcaattttt ttcctcactt
    38101 ttatcattat tagttttgac aagtcttata gaattatata ggggaaaggt aaaagattca
    38161 aggcaatcga acattctttg tgtttcacgt gaaacagaat gaaaaaaata aaaataaaag
    38221 cggagcgaaa atagctacta taggatttat tagtttgcaa cagcataatt tttgacgtta
    38281 tttataagag ggagtactat aaaactgtaa aagaaatgaa agaaggattg aaaatggatg
    38341 aaaaaagaac catcgactgg ggctcattga ttttgggaat tttatttgta cttgtctcat
    38401 tgttatcatt tcaagaccct gtcggaaatt tagttgcaat tgtagtagtc tttgcgattt
    38461 ttgcctttat taaagggata tttgaactgt ttgtacggaa cagattaaaa gagctaacag
    38521 gatataaagg aaagatgccc ttaataatcg ggatcatcga tattctagtt ggcgtctttt
    38581 tcttattcaa tattggtgca ggagtcgcag cattgccttt tgtttttgca gtatggttta
    38641 ttgctgattc agttttagcg ttatttactg ctgacttggc aagaggagta agtgaaggat
    38701 attattggtt tacgatcatc gtcaatattt taggaatttt attaggaatt ttcttattgt
    38761 ttaatccaat ttcttctgcg ttgacattaa gctttttagt tggattctat tttatgttat
    38821 ttggtatcac acatatcgtc tatgcattta gataagtaaa atcaaacaaa taaaaaagcc
    38881 ggcttccgat tacagtttta ctgttgtaat tggaagccgg cttttttatc atggacaaat
    38941 atgcacgagg tgatttttag gtgtcgagac aaatttatgc aaaaatgtga gaagctatat
    39001 acacaaattt tatcttaata ctcgaagcat agcgcagttg tcacaacctc ttttcatata
    39061 attcattcaa tactggcaaa tcatggactt catatttttc tttgaatgct tggatttctt
    39121 cttcagaata ttttcttgga tctaaatgca gatcttctac tggcaatggg cgcttgttat
    39181 tgatcttcac atcgattact acaggacgat ctgattttgc agctgcatca aaggcaaatc
    39241 gaagttgcga gtattctgtg actgtaaagc tatttgcccc gagcgcttct ccaactttac
    39301 cgaaatctgc atcttctaaa aatacaccaa atttcttttg ttccgtatct tcttgttctg
    39361 cttcgatgaa accaaaagaa tcattcgaaa agacaacatt aataattgga agctgatatt
    39421 tgacttgtgt aatgatatct tgcatgacca tagcaaaccc gccatcacca cttaaggtaa
    39481 atacttgttt ttctgggtag cttagttgtg cggcaattcc tcctggcaca ccattaccca
    39541 tagttgcgaa ccatccagat gtcgtatgtt tttgtttacc gttcatattc aataaacgaa
    39601 tagaatggat agtcgtgtta ccgacatctg tgacgaaaat cgcatcgtct tcagcaatac
    39661 gattgatttc tttatagaca gcctctggac gaatcggttc ttcctctcga tcttcaaaag
    39721 atttcaacca atttacccat ttttctttat tttcttgatt tgctaggtac cagctatcag
    39781 cagggcgagc atcccctaac tcgacaagtc tttgcaaagc tgtgtttgca tcaccgagga
    39841 tcgacaaaga tgtttcatgg cgtcgtccaa attttgacgc atcgatatcg atttggataa
    39901 attcagcagt tggattaaaa aatgcacgtc caaatgggaa gtcgctaccg acaaataaga
    39961 tcagatcggc ttctgccaat gcttcatttc cgggtttagt agcgacacgt ccagcaaaac
    40021 caagaaagtt ttcataatca tcaggaataa ttccttttgc tagaacggaa gcgacaacag
    40081 gaactgaaaa atgttctgag aattctttga tttgcggaaa tccgtttcgc gttccttgac
    40141 caacataaag aactggtttt tttgcttttt caagataagg caaagcagct agcaaatctt
    40201 tttcttctgg taatatcaca cttgttttgt gagtgtgagc ggtggagaaa ggttgttcgt
    40261 caatttcttc aaaaccaaga tcaacaggga tagtcacgat agccacgcct ttatgctcat
    40321 aggcggcttt aatggcttca tctactacat gcggaagact ttgtggtgtc atgactgtac
    40381 gattgtatac gctaacatct gcgaaaatag gattttcatt tagttcctgg aaagagttat
    40441 agttcatgga tgtagaagca acttgtccta agaacgctac tagaggcaca tggtccatct
    40501 gtgcatcata caaaccattg atcaaatgtg tcgcaccagg tcctgcagag ccgaagacag
    40561 cgccgacttt ccccgttaat tttgcatctg cagcggctgc gagtgcgccg acttcttcat
    40621 gacgaacttg aatgtagttg atttcggttt tttcttgata tagcgcatcc ataattgaat
    40681 tgaaagatcc tccgggaatg ccgtaaatat ggtcgatacc ccagctttca agaactttta
    40741 ccattgcgat tcctgcattg atttttgaca tggtgtttca ctcctttagc aatgatgata
    40801 cataaatttt ttgtatctag agtatagaac tttttatcga aaatcccaac taattcgtct
    40861 tttcacaaaa atgtagtcat gtttttggga atatgctaga gtagtacata gatagattca
    40921 agagagggga atggcatggt tgaatggcta ttgagacttg aaccttggca gcaagcactt
    40981 gctgggacag cttttactta ttttatgaca gctcttggtg ccgggttggt ttttttcttt
    41041 aaagaaatca aaaaagaagt gctaaacttg atgttaggat ttgcttctgg tgtcatgatt
    41101 gctgcaagtt tttggtcttt gttagatccg gctattacaa aagcagaaga aaatggagat
    41161 attgcttggc tagttgtaag tattgggttt ggtttaggcg gtgtgttttt atatatggca
    41221 gataaaacac tgccccatat gcattttgga ccacaacatg aagcagaagg attgcctacc
    41281 catttaaaac ggacgatctt gcttgttttt tctattacat tgcataacat tcctgaaggt
    41341 ttagccgtgg gggtagcatt cggtgcagca gcaactgcgg ataatccgac agccgctata
    41401 ttagccgctg tttcggtggc gctaggtatt ggtatccaaa acttcccaga aggagcagct
    41461 gtatcaatcc cgttgcgaca agaaggtctg agtcgtaaaa aggcctttgt ttacggacaa
    41521 gcttctggaa tcgttgaacc aattgctgga gtgattggag cgctactagt aacgaaagtg
    41581 gagctgctgc ttccttatgc acttgctttt gccgcaggag caatgattta tgtcgtggtg
    41641 gaagaattga tccctgaagc acagcagaca ttgtccagca aacgtcattt tgcagttttt
    41701 ggcgtcatga gtggatttat cattatgatg attttggatg tggcattagg ataaataaaa
    41761 aaaatatata tgatatatca aatagggccg cgaacttata tcgcgaccct atttttttag
    41821 taagttatat cataatgaag tgaatggtat catacattaa taatagtttt ttctatgtgt
    41881 atttcctttg atccagcgaa caagccagat gataagtgcg attgggatta gaactttgac
    41941 cgcaaaccat aaaagcccgc ttaggacact gacaaaaaga ctgatgacga agctagctgc
    42001 aattagcact aaaagaacca tgaagatatt taagaacata tttttttgac gcatacaaaa
    42061 ccctcctctt gttcattctt tactatagaa aaagtataac agggattgtt taaaaacacc
    42121 tccaactgaa gactgatttt tacttcatct acttaaatga tcaaacaatt gctttttctc
    42181 tggtttatca tctaaaatag agcggaaaag gaggagaata tcatgcctaa aaatcgtctt
    42241 gaagcattta cagatgctgt aatcgcgatt atcatgacta ttttagtttt agaacttcat
    42301 gaacctaacg gagacacgtg ggaggcgctc gctgcattag gttaccgatt ttttatctat
    42361 attgtcagtt ttatcatttt agcgatttat tggaacaatc atcatcattt atttcaagtt
    42421 gtacataaga taaatggacg ggtcttatgg gcgaacagtt tctttgtttt tgcgctttcg
    42481 ctttttccgt ttgcaacttc atggatcagt gagtacatca atagcctggc tccagaaatg
    42541 acttatggtt ttgttacctt gaccgctaat attgcgtatt atatcttggc aaaagaactt
    42601 gtcaaagcaa ataaaggcca cgagaaagca ttgaaggcga tgttgaataa ttacaagaaa
    42661 tcgtatctat cgattggttt gaatgtgtta ggaattgtct tagggtattt agtagcgcca
    42721 gtagccgtgc tgatcgcaaa catcgtgatt ctagctgctt ggatcatccc aagtcgtacc
    42781 atcgaatcac aatatcggta aaatgatccg tgtttaaaat ttaagagaaa aatatagaaa
    42841 aaataaataa acgatcaaat atccgagtga tactagtatt caaagaggga tgcagatgga
    42901 tcaaaaaaga attcatgtag gactgattac tagttttgtc acgatgctta tttatttgga
    42961 tcaaggtcat ttgacttgga cagtagttgg tgtcgtagga tttttgacat tattcacagc
    43021 aataaaaaaa taaacatctt tatgtaatct gatgttctat ctatttaaga aaagcatgtt
    43081 tacagcagta tgattctgtt gtaaacgtgt ttttatttgt ggaaaattta atttttagaa
    43141 aagtgtatcg aaaaatagat agttagtttt tccacagtgg ataacttcgt aagagataaa
    43201 aataaaaaat tagtcaaaga agggcgtata gatttctttt gataggagat atacaacaga
    43261 aatgaataaa tattaacgtg ttttcaaaca gtataaaacg gtgtggtttt tggaataaaa
    43321 aaataacata tctcatttta cgcttttgtt attttatact taaaaaataa cgacacagaa
    43381 aataccgtgt ctcagatttc tctactactt ctaaaaacta ctgttttttt cctttgaaat
    43441 gccttcaaaa agtaggatca ggcagaatat actggcagaa tcaaggagaa gggagcctaa
    43501 ataaggagaa aaaccataga aaatataaag taattactta taaaacaagc tttttataga
    43561 aaaataatat acctgagtag ggtataaatt aagacggaat tcctttctag attgagatat
    43621 tgactaggaa gaatgttaag attttaagcc tttaagctaa aaaaaaaccc tttttgttaa
    43681 ataaggggaa tatagcctgt cagtttcaaa ctgcaagtcg tcctgctgca ataatatagt
    43741 agattagaga tgaaaataga tttttttaaa ccaatgactg aataaaaaga ccgtcataga
    43801 tacacattgg aatgtgtcta ttacggtctt tttttacgaa cgattttatt gaagacggac
    43861 agttcgggtc aaaaataaaa aagctacgat cagaaataag aataaaatgt atcccaaaat
    43921 aatggctaga cggtctaact tatttgtcga tagatgtttg tttagaagtt gataggccca
    43981 taaacctatc agtcctcctg ttgtattagt tatcaaatca gtgatgtccg ctacgccaat
    44041 accgaatagg aattgaatca attctgccaa gaagcttaca aggaaaataa tccctaattt
    44101 tttagaaaaa gaaagtctct tgaaattgac attcaaaagc accccaaaag gaaaaaagac
    44161 aatcaagtta taagtggtct cacgtaatac cgtcgtattt tcaaaagaaa aagtagaaaa
    44221 agggacgaga ttgacattgc tgtaagaata agtgagaaat tgtggaagat taaatgatag
    44281 cttgaataaa atcaaccata atagaaagaa taaataaatc cctaataaaa attttgatac
    44341 ataccgcata gacatctcct ccatttaaaa agtataccat cgaaaaccgc tgaaaaatca
    44401 taaaaaagta tgaagtttaa ggaccaacgt agttatcgta cgaaaattag aagctttttt
    44461 ttgttgggaa tccggtttct ttaacaaagc taagatagcg agttgcttgg aaaagttgct
    44521 atcttttttc tgtcaaaacg actcggaatg ttcgtttttt gttctaattt ctccaagttg
    44581 tttacttttt gatactaagt ttatgaaaaa tcaagaaata gttgttatac taggtaatgc
    44641 tgacaaacgg gattggcatt tcatcttggt tcagcttttt ttccaattac taggaaggag
    44701 ggatagattg ttcaagactt attttcgttt caataaaata caagataatc cttttcgtat
    44761 catgaatctg atgctactta tctttattgt attatggtta ggttacataa atcatgattt
    44821 tttgatttca agtttttcat cattagggat ctttactttt ttctattatc aaaacatacc
    44881 gatgaaatat ttgctgaaac gtatgtttct gatcggttgc ggactgttgg ttgctttcgt
    44941 tttggggatc ttatcgactt atgttttatg gcttgaacca tttgccgtag ctttggttgc
    45001 tttttccagc agattcgtgt tgcgattatt ccatatttct aaaccaggtg gcttgttttt
    45061 tgcgatgctt tctgccatgg gaacgagcat gcagctgcca atcgctcaat taccgatcgt
    45121 ctcactttat ttttttatgg gtgtcgtttt tgccctgatt gcggcagtga ttacaaaatt
    45181 actggattca cggcctgagc agacaattga aaaagcaact ttaaaagaaa gatttcacga
    45241 agagccttta gtgatcattg attctgtttt ctacagcgct gccttatttc tttccgttta
    45301 tgtcagtcac ggcttgaatc tgcataatcc ttattggttg accttgtcat gtgcatcgat
    45361 tttgctagca gaaaacttgg atgcgatgaa gcatcgacaa gtccaatatc tgattggatc
    45421 gatgggtggg ttatgtgtgt cggcattctt gtcatttgtg ccgtttacgc agttgcagac
    45481 catttttctg atcacttttc tatatggaat cgcacaattt ctagttgcta gaaattatgc
    45541 agttgctaat atttttctta atccgatggc gttgatgcta tctacactta ttcgtggagc
    45601 atacttgatt tctttgatcg aatatcgttt tttagggatc gtcataggaa gtttcatcgg
    45661 tttaggtgtt gcgtgggtaa tgacggttgg tttgcaacat tatttaacgg ttgttcgtca
    45721 aaaattagaa tagaaggaca aatatatgtg ccaaaagagg ttatgacaag atttttgtca
    45781 caacctctaa ttcaaggtgt tcaaaagcca gattctcagc attaagtcaa attcacacaa
    45841 aaatgtggaa aggaactttc aaaaaaattt tatatttatt ctatcaaaaa attttatatt
    45901 tattctatca aaaaattttg tttatgatgg taactgaata aactttcctg agatggtcaa
    45961 tgctttcctt gaaagtctta cagatattct ttcttcatag aaagtttaag ttttatagtt
    46021 agtgtacaat aaaagtatgt ttataccata tggtgtccgg ataatcagtc atttaaacaa
    46081 tgaggttcaa agatatgaaa aggggaaatt tgatgaagaa aataagcaat gaaatccaaa
    46141 ttctggcaga aactttaact cttcccaaag tcgttataga gcaaatgatt gtacaagcaa
    46201 aaaacatcct tgatgaggtg tttgagcaat atagtcatga actaatggat cctaataaag
    46261 caaaggcgac tgcaaagaaa atagacaaag tctatgaaga ggaacctttt gcagcattag
    46321 ctatttatct atatgcagct tctcaaagtt ggaaaaaaat ttatcaacca ttgaagattc
    46381 caagaactat ctatttggca acaatgaatg cttttactag atttattcat gaacatttcc
    46441 aagtaacagg aagctatcgc tttgaccgtg gtttttggat ttggcattac actagtggct
    46501 tgatctttcg gattggtgaa ttggagtacg aaatgacata ttttccgaaa gggtacacgg
    46561 atctaagatt agaaggaaag cagtgccttt ctcttcatat tccttccgat gcagatttat
    46621 ctcagaataa gataagagat agttacgaaa gtgccattcg tttttttgaa ctttattttc
    46681 ctgattacca ttaccaagtg atgtacacag atacttggtt actatcaccc aatcttacta
    46741 aatggttgaa aaaagagtca aaaatctgtc tttttgcagc cgattatcga ttattatcag
    46801 ttgatgaaca ggacgatagt ggagtccctt ggatctttgg acgagtagat gcccaaatac
    46861 atgattatcc agaaagtacg agtttacagc gacaagcaaa agagcaattg cttgcaggcg
    46921 agcacattgg ctctggctta ggtattctta cttcataagt ttagtacttc gaaatagttt
    46981 aaaagagcgt gagacaaaag taaagaacac ttttgtctca cgctctaaac acgtataaac
    47041 ggcggaagca gaagcaactc cttcggaaat aagctgaaat tcacaaaaat ttgaaaagca
    47101 attttcgtga atttcttctt atttcttgga gttaaacgct tctgtcccag cctctttttt
    47161 agtgttctat cgaacacaca gtacgttcaa taggtaaact agctataaca atagatatta
    47221 aagttaacgg acaagagggc cttttttagg tagctaaaac gtaataatga aaatttattt
    47281 ccagagatag gagtcaatca gctagtctga tcgactgttt taacaagttg actttcattt
    47341 taacttttga taccatttaa aacacaaatc gtaattgttt cgatttgtgt tttttagcat
    47401 gactacaatc aaagaagaaa gtgggtcgtc catatggaaa aaacagatat ctcaagtgca
    47461 taccgccgct tgaaaagccc aaatatcaaa acacgaaaac gtgcgctgaa gatcatcaaa
    47521 gatgtgaaac ggaatagtgg gaaaaggtaa gaagaaggaa acttaattaa aaaaatagcc
    47581 gaaaaacgtt tttcggctat tttcaataat cggtttttgt gtaaggtttc cgaaagaact
    47641 gctgttgatt ttccattttt aacatatgat aaattggtag aatctttctt ttcaaattga
    47701 taccattccc taattccagt tatatagtta actacagaac cacaaagcac gtacgtttat
    47761 aaaagtatta tctgtagtta tttttcaatt ccctttcaac ctcttatttt gaccagtagt
    47821 attgatcact ttacctttta acacctttgt tcgtttttga aacattttta gtcaagaatg
    47881 gaaacgtaac tacataatca aaggttttgc gaaatatttc atgaaatatt tcatgtagaa
    47941 gcgagcaata cggttgcaaa taaccattat cgtttaataa gcagttacga aagctcccaa
    48001 tatctctaac gttcagctca ctccatttct tttcttcaaa aaaatcagtg attcgtatct
    48061 ctttctattt gtcgaaaaag ttaactttaa aaagtaacgc cgaaaaaata tgcaaaaaaa
    48121 taaaaaagca gttactattg ctagaataac atcaaggaat aataagtttt ggttttcaga
    48181 taatagtcga taagttgtgt attggaattt tagatacagt aataaagtat ttttcatgaa
    48241 attttgtgag aatcactatt acaagtatct ttaataaaat taatggttaa ggaggaactt
    48301 aaagtagaat gtaaatgaat agttgtagtc agtcgattgt gatactagac tcaaagttgc
    48361 aggaataagt ttttcaattt gtgattggaa gataaaaaat gaaaaagaag ggcttttttt
    48421 tatactttgt tgattgtagt gtttattttc cctctgttta gccaagtaac attttctatg
    48481 actcaaccag tttcaagtga ggaacatgat aacctttttc gtgctacaga agagtttaag
    48541 aaatatcagg aaaatattgt tccggagact ccattagcta gtgagccaat tactgatatt
    48601 gatggaaacc aaataggatg gtatatacag tacgaagtta tggtggtaaa taatgactca
    48661 atagtaaaaa atacagtagg cttagagcta acaccgattg aaaaggtgag ttcattgtta
    48721 acgtatattt atactgatga aagtgacgag actgagatca ttttaacgga ttactcaaaa
    48781 attgctactg ataaaaagta tatattgtgg atgtagacac tagtgaaata ctttatgata
    48841 tagaaattga tgaaaattta ctagatgtag cacaagaaat cgatcatcaa aagcaggaag
    48901 ctattcgata tgctggtaga aaagggaaaa gaaaatattt attacgtgaa tgtagcaaaa
    48961 gttagagaag atgaaaatga gtggaaagaa ttcaagagtc gctactcaat taactcgact
    49021 ccgacattta cagtttacag agaaggatcg atagaaaaaa ctgttttttg gactaaagaa
    49081 agtggaatgt ctttagctga agtagaagag tttttggatt atgttagtat gcaacagtaa
    49141 gggagttctt attatgaaaa attttgacac atattatgtt attgtttttt cgatatcttt
    49201 gctgttaata ttactaactt taatgcagta taaagagtat ccagagtatt ttattttaac
    49261 ttttgtatat ttagtaagta gctacacact tctatataaa ttcagaagtt cttctagagt
    49321 ttctaaagtt tgtttcttaa ttagcttatt gattctataa tatttttgat ttatatagga
    49381 aattaaaaat attatagaat caacactcag agaacgggtt ggtttttaat agatttaata
    49441 agtactgata atgaaatttc tcctggttgg gaaaacgaag ttggttaccc tgtagaagaa
    49501 ttttttcaag attactttgc ggagtatgcc gataggataa tgagagatta cgtaacagat
    49561 aaaactcaag aagtcatcaa tcaatcccag tcattaaatg aattatctga taaggcgaaa
    49621 gaagaagcag ttgccattat ttcttcaggg attagtgact atattgatat gagtggtgaa
    49681 atcaattatg gcgataaaga caaaattgta cgcatgataa aagcttttat caaaactttt
    49741 gatgtgaagg cagatcttaa gtttaatgat acttacctag taggaaaatt aattaatatc
    49801 cttgggacag agaaagatac ggaaacgttt atttcctctt tgtctatgtt gtttacagat
    49861 aagcattttt caactcagct tggtggagag gaactagtgg aaatctttta accattacgc
    49921 ccagcattaa taaaagtata tcaaaaaagt actcctgatg atttttaaga ttggtttgag
    49981 aaataatgtg aaaacactat ttttaatgtt aattatagat agagatgaac gcgtcatatg
    50041 gttaaaagaa tgaaaaagtc aaagatacac tgctatattt cactaaggat atagcagtgt
    50101 atctttcatg tcgtttcact ggcagttttt tataaaagga ggtgtgcatt tcagttgctt
    50161 ttctttggta gttagttgaa tcgtttaaga attaacggat gtggcagaca ggtgctctgt
    50221 ccaaaaacca gtaaaatctt tgatggttcc atctttattt agctgtgcct gttcaaatac
    50281 tgttttgttt ttaccgaatg gatcaattgc aataattgtt ccgatccccg cacgtttggc
    50341 agcaagtaat cctgagtaag catcttcgat aacaagacaa tcagccggag ctaagctcag
    50401 tttgtctgcc gctttaagaa aaatatccgg ttgcggtttc ccagggaaag agccgtcgtc
    50461 atagacaatc ttgtcccagt caaaccagcg ggctaaatcg aaaatatcaa aataaaaagc
    50521 aacattctct ttgacagtag ccgtggcaat cgttaatgga atctgttggt cagtcagctg
    50581 gtcaagagtc gcttcaagcc cttttgtcaa ctgaagctcg ttttcatttt gcaagcaaag
    50641 catacgataa tagctttctt tttcttctga caatacggcg atctcagagg cggtcaaatg
    50701 ctctgaaatg aaatgtttca aaatctccgt attcgtccga ccatgaatat tttttaaaat
    50761 atcctcgtct gataaaccat cttttgtatg atcatgtatc atatgcagcc aagcagcttc
    50821 atgcagatga gagtccaaaa acattgttcc gttgaaatca aatataatcc ctttcatagt
    50881 tacgctccta tagtggtatt ttcggttgaa tcagcaattt gcagatcgac atattgtgca
    50941 tagtgctctt gaacctcccg cgagatctgg cgatccgtaa tgagcagatc gaaatcatgc
    51001 aaattataaa acacataaaa atcatctcga ttgaattttt tattatcaac gagtagatat
    51061 ttcttacggg aattatttag agcgatctgc tgtgcttctc cttcttcggt actgtaagta
    51121 gagatcgctt cgttgtgaac gccatttgaa ctgataaatg cttttgtaaa ctttagtctt
    51181 cttaaattgt cgttggtgat cggtccgaca aatgcgccgg tatttttccg gaaatcaccg
    51241 ccaatcagta gaatttctgg tccatctgct tgagcaagaa tatcaaaaac tggataatta
    51301 tttgtaatga tccgaatttt cttgttcagt aaatgcgtcg ccaatagttc gattgttgta
    51361 cctggtccta agaaaatcgt ttctccctcg tgaatcaagg aggctgctgt ggcagcaatt
    51421 tctttttttt cttgaatctg cagagtggct ttttcagtgt gagaaagttc ttgatctaaa
    51481 gtgtaggaaa gactttgagc ccctccatgg acacgcagca gcttgcccga tttttctaat
    51541 tcatctaaat ctctgcgaac ggtcatatca gaaacatcta attgattgat gatttcatta
    51601 acggtaagga ttcctttttt attgaccatt tctacgatag taagcaatct ttcttttttc
    51661 aacattgtct tcacctctaa tttaaggata atctatcata taaacggaca acagtcaatc
    51721 taattcgaac aaaagtaaac atttagggtg gtttttatgt ttgttacaat agattttatt
    51781 gctgttttct ggtttttatg attatttgtg tttgtttttg ttgacaaatg ttttggatgc
    51841 gtttacaatg caatcagtta gaaagagcga aaactgatta tagatttgag gagagatgta
    51901 catgcttaaa ttaccagaag attttatttt tggcggagcc acagcagcct atcaggttga
    51961 aggagccact aaggaaggtg gcaaaggcgc tgttgcttgg gatgactttt tagaggaaca
    52021 agggcgattc agtcccgatc cggcaagtga tttttatcat caatatgcaa aggacattga
    52081 attgtgtgaa cgttttggtg taaatggtct aagattatcc attgcttgga gccgcatttt
    52141 tcctgatgga gctgggaaac caaatccaga aggaatcgct ttttatcatc gtgtgttcga
    52201 agaatgtaag aaaagaaacg taacgccgtt tgtgacgttg catcattttg atacccctaa
    52261 acgtttgttt gaccatggag attttttgaa tcgagaaaca atagaagcat ttgtttccta
    52321 tgccattttt tgttttcatg aattcaaaga agtcaaggtg tggagtacct ttaatgaaat
    52381 ctatccagtt gcaaccaatc aatatttgtt aggtgttttc ccaccaggaa tcaaatatga
    52441 ttttacaaag atcgtcgcct gtcttcataa tatgatggtt gctcatgccc gtgtagtgaa
    52501 ctatttcaaa gaaaacgaac ttccgggtga aattggtgta gttcactcat tagagacgaa
    52561 atatgcggca acagacgcgc cggaagataa gcatgctgcc tttttagacg atgcattgtc
    52621 gatccgtttc ttattagatg ctacctattt aggctattat tcaactgaaa ccttgactgc
    52681 tcttgatgag atatgtgaag caaatcaggc cagctatcat tttcctgaag aagatttcgt
    52741 tgaattgaaa aaagcatcca cgcgtaatga ctacttaggg atcaatcact accaatgcca
    52801 ttttgtcaaa gcttacgatg gagaaaatgc aatccatcat aacggtacgg gtgaaaaagg
    52861 gacctctgtt tataaagtga agggaatcgg agaacgtatt tataaagaag gaattcctcg
    52921 aactgattgg gactggctga tttatccaga aggtctatat gacttgttgc tgcgaattaa
    52981 aagcgattac ccacattaca acaaaatcta tatcactgag aacgggatgg ggtataaaga
    53041 tcagtttgaa gatggcatta ttatggatca gccgagaatc gactatttga gagtctattt
    53101 ggaatcctta agcaaggcga taacagccgg ggtaaatgtg aaggggtatt ttttgtggtc
    53161 gcttatggat cttttctcat ggacaaatgg gtataacaaa aggtatggct tgttttatgt
    53221 tgattttgaa acccagaagc gttacccaaa agaatcagct tactggtaca agttggtcag
    53281 tgaaaccaaa acgattattt aataagtgat aatggaggaa gaaaagatga ataaagagga
    53341 attacaaatg cttggttttg agatcgttgc atattcaggc gacgctcgca gtacattatt
    53401 gaaattattg aaagaagtaa gacaaggaaa ctttgaacat gttgattcgg cgttgaaaga
    53461 agccgacgaa aatttaaccc ttgcacataa ttcgcaaaca aaaattttag cggaagaagc
    53521 atctgggaaa gagatggaga tgggattcat ttttatccat gggcaggatc atttaatgac
    53581 cactttattg ctgagagatc tgattcaaga ctttattgta ctgtacagac agaatcaagg
    53641 ataggagaag aacgctatgg atggaatcat taaacaaatc gaaaaaggga aaccattttt
    53701 tgaaaaaatc tcacgtaata gttatttagg agccgttcgt gacggatttt taacagcgat
    53761 gccagctatt ttattttcaa gcattttcat tttgattgct gcggttcctg agatttttgg
    53821 ttaccaatgg cctgaatctg tctccacatg gctatggaaa gtctataatt attcgatggg
    53881 tgttgtaggg ttactcgttt cagcaaccac tgctcgctgc ttggctgatt cgatgaatcg
    53941 tcgcttaccg aaaaacaaag taatcaacac cacctctgtg atgctggcct ctgtggtaag
    54001 tttcctgttg ttaagcgtct ctccgattga aggtggattt tcaacggaat atatggggac
    54061 aaagggacta ctggcttcct ttgtcgctgc atttttaaca gttaatttat ataagttttg
    54121 tgtgctgaaa gatattacca ttaaaatgcc taaagaagtt cctggaacga tttcgcaaac
    54181 cttccgagat atttttcctt tctctttttc agtatttgcg gccgttttaa ttgatttagg
    54241 cattcgacaa atcttccaaa tctcatttgc agaagcaatc attacggtgc tgcagccgct
    54301 atttacagca gctgacgggt acttaggaat cgctattatc tggggagcga tggcgctgtt
    54361 ttggtttgtc ggtgttcatg gaccgtcgat cgtggagccg gcaattgcgg caattatcta
    54421 tgccaatgtg gaaaccaatc tgcaattgtt caattccggt gaacaagctt ctaaagtact
    54481 gacggtgggt ttagggaatt ttgtaggaac tatgggagga actggggcaa cattggttgt
    54541 tccttttatc ttcctactct ttgctaagtc taagcagttg aaggcagttg ggaaagcttc
    54601 ctttattcca gtaagtttcg ctgtcaacga accattgcta tttgcggcac ccatgatttt
    54661 gaacccttat ttttttattc catttttgtt aacacctgtt gtaaacgttt gcctgttcaa
    54721 gttttttgtc gatgtattgg gcatgaacag ctttatgtac gttttgcctt gggcaactcc
    54781 agcaccgatc ggtttggttc taggaacggg catgggtatc ttagcttttg ttctagcagc
    54841 ggttctaatc gtcgttgact tcctgatcta tctaccattt tgcaaagcat acgatgctgt
    54901 cttagtagag aaagaagcac aaaaagcaga ggtgatcgca accgaggaag gtgcttctgc
    54961 cgatgtacgt gaggaagtac ctgtggcagc gagtcaagtt atcagcgatg caaataaaga
    55021 aatcaatgtg ttggtacttt gtgctggcgc agggacaagt gcgatgttag ctaatgcttt
    55081 aaaaaaaggt gcatctgaat cgaaagcacc gatcagtgca atggcgggtg cttatggttc
    55141 tcattacgaa atgctgcagg attttgatat ggtggtctta gcaccgcaag tcaattctta
    55201 ctatgatgat atcaaagaag acaccgatcg cttaggaatc aagctggttg cgacaaaagg
    55261 agcagaatat atcggattaa cgagagatcc tgaaaaagct gttcagttta ttctgaacca
    55321 atttcaataa aggaggagcc ataatgaaaa tgggaatttg gttgcgtaaa gctgttttat
    55381 ttgcagctgt gttaggggct ttgggggctg tttcaaaaac tgttgaagca tctgccagcg
    55441 aatttattcg cggagcagat atttcgatcc tgtcagatat ggaaaaatct ggtgcaaaat
    55501 attatgaaga cgatatttca aaagatgcct tagagatttt aaaaaataat ggtgtcaact
    55561 atgttcgact gcgtttgtgg caggatcctt ataatagtaa tggagaaagt tatggagcag
    55621 ggacaaatga tctggaaacg acgattgacc ttgcaaaacg agcaaaaaat ctgggactta
    55681 aggtgctgct ggattttcac tacagtgatt tttgggttga tcctgggaaa cagaatcttc
    55741 ctaaagcatg gcaaggtctg acctttgaag aaatgaatac ggcattgtac gactatacaa
    55801 agaacgttct gtcggaaatg aagcagctgg acgtttatcc tgatatggtt cagatcggca
    55861 atgaactgaa tagcggaatg ctctggcctt atggcaagtc ttggggagaa ggcgggggag
    55921 aatttgatcg attggctgct tttttgaagt ctggtatcca agctgttcga gacactcaac
    55981 ctaaaacaac tccagtaatg ctccacttag ctgatggtgg cgatacagga gcatttactt
    56041 ggtggtttga tgaaatcacg agtcgaggtg tgtcatttga tttaattgga gtgtcgtatt
    56101 atccgtattg gcacggttca atgaatgaac ttcaaaccaa tatgaatgcg atcagccaac
    56161 ggtatggtaa agaagtgatc gtagttgaaa cagcttatgg gcatacaaca gcgaatgccg
    56221 atactatgcc aaatgctttt ggtgaagccg aagcagctgc ggggggatat gaaccaacac
    56281 cgacaggaca agcagagtat ttgctggatc ttgccgatcg gattcaggca gtaccgaata
    56341 atcgcggggc gggcttcttc tattgggaac ctctttggta caacggaaat gtgagttggg
    56401 caacacaagc aggtatgaat tatctcagtg ttcaatccac tatgggaaac gaatgggaca
    56461 accaagcgat gtttgatttt gctggaaacg ccttgccaag cttgcgtgcg tttaaacaag
    56521 caggggcgca aataaatcta gttaaaaatg caagtttcga aagcgatgga ccaacgacca
    56581 gtccttccaa ttggcaaacc tggtttcaac aaggaaccgc taagggtacg atcaaaacgg
    56641 aagcgggcac tttttttggg gactacaaac taactttttg gcaggatcaa gcatacgagg
    56701 catcagctta tcaaaatgtt agtggcataa gcaaaggaac ttacacattg agtgcctatg
    56761 taatgtctgg gggagagttt gatactaatc agttatatat caaaaattat ggtggagcgg
    56821 aactaaatac tgcggttgtt aaaacaagtg aatggacaaa aattacaatc aaagacattc
    56881 caattacaac aggtgtttgt gaaattgggg tttatagcaa ggcttcagga aatgcttgga
    56941 cgaacgttga ttttgtttca ttggtgaaac aatagactgc ggatcgtttc gattcaagat
    57001 cggaggttcc cttcagccac atcgttagcg tagaaggcag gaatcgaacc tgcacctcgc
    57061 ctttgccaaa aataaccaga aacgatttcc agtcattttt accaaaacga gtaaagcacc
    57121 agacttcatc tacactttgt attatgctaa agagagttca acgatttcgt aagaagcaat
    57181 gaaaaaattg caaaaagttg tgcagataac ataaagtttg tttaagaaag ggtaacctta
    57241 gaattccgtc gtgaatatga tttgagcact tagatggata gaaaaaagtt ctcggaaaac
    57301 agttcgtttt tcgagaactt ctttttatga taagaatgaa acaaattaac ttatattata
    57361 gtctcttttg gtagggaacc atcttatttt taatgaaaat caagcatttt agctattgaa
    57421 gaatgttgat ttatagggat tccccctcca tattatgttg gctctttatt cccactctgt
    57481 tttcaacgta aagtgtataa aacagaatgc gatactatca agggagttaa aacaatatac
    57541 agaacagtaa aacactataa ataaaaataa aagtgcaata aaagtgcaat ttttgcacct
    57601 aatcatactc tgtttatata tgaaaactag attctgaatc caatatttgg ttaacgagag
    57661 gcgttcgaat ttgaacgtct tttatatatt actttcaaat aaatatgagg tagaatacta
    57721 tctattttct ttttaaccca attgttataa tggagagtgt aaaatatttt gtgtaaatag
    57781 aaaaaaggaa gtcccttctg tagaatagag ttaccacaac acattcacag aagagaggac
    57841 ttccctatga acgattttac tacagaaatt ctaaagactc tagcgaacaa aggcgatttg
    57901 aatgaattat tccgtgtcca tttggagaaa gcagtcaata cgcttctcaa aacggagtta
    57961 acggctttcc tagattacga aaagtatgat cgcattggtt ttaacacggg taattctcgt
    58021 aacggctcct atgaccgtac ggtcaagacc gagtatgggg aacttcatct ccagattccg
    58081 cgcgaccgca atggtgagtt caagcaacag actgttcctg cttatagacg gacgaatgac
    58141 acgttagagg agaccgtcat tcacctcttc cgaaaaggta ttaccatgtc ggaaatcgca
    58201 gacttgattg agaaaatgta tgggcattac tacacgcccc aaaccatgtc caatataaca
    58261 aaatcattta cagaagaggt aacggcgttt aatgggcggg agcttcatga ccgttatgct
    58321 gctatttata tggacgcaac gtatattccg ttaaagcgga aaaccgtcgc caaggaagct
    58381 attcatatcg cagttggcat tcgcccggac ggatcaaagg aagtattgag ctatgcgatt
    58441 gcaccgactg aatccatcac gatttgggag gaaattttat tggaccttca agagcgcggt
    58501 ttgaaaaatg tcctcctgtt catcacggat ggcttaaagg ggatggtagg agcgattagt
    58561 cggttctatc ccaaagctcg ttttcaacat tgttgtgtac acgtttcccg taatatcagt
    58621 cataaagtgc gtgtcgatga tcgtaaggaa gtctgtgatg attttaaaat ggtgtatcaa
    58681 gcctcatcta aagaggtggc gttggaagca cgtggtactt ttgcggaaaa atggaaaacc
    58741 agctatccaa aagtggttga atcgattctt tcgaacgatc acttgctcac tttctatgat
    58801 ttccccttgg ccatacgcaa gagtatttat tctacgaact tgattgaatc ctttaataaa
    58861 caaatcaaga aatacagcca ccgcaaggaa cagttccaaa atgaagagtc gatggaacgt
    58921 ttcttagtct cgtcttttga tacttacaac caaaaattcc taggtcgcag tcataaaggt
    58981 ttccaacagg ccgaaggcga gctcgaacaa atgctaagcc aactgattga gaattagaaa
    59041 caatctgcag tagggaagaa tcatttacac aaaattattg acgctccctt ataatgagaa
    59101 cttttactaa cataatttat gataaactta ctatataatc atattaatta aatagttagg
    59161 agatctgctt atgtttatat ctactcttca aattcgaaat tttagaaatt atgaatccga
    59221 aatctttcga ttcgataatg agacaaatac tattataggt gagaatgatt cagggaaaac
    59281 caatgctctt actgcattga gaatcttatt agatgatagt tattactata gtagtaaaac
    59341 actaaaagaa tcagattttt ttcatggaat tcaaaatggg tggcaagggc attggattat
    59401 tatctctgcg acatttgaag gaatcagcga agaagaattt gacaatgaga tttgtgcttc
    59461 catttcttta aattctgaaa gtcaaacaat cttagaagaa ttgatttcaa atgcagataa
    59521 aggtgtaggt agtatttctc tatttattag acctaacaaa gctattagaa agcaattatt
    59581 tgatatttcc actgaattag actctcatca atttaacgaa tttagaaatt ctattcgtct
    59641 atccgactat gaattttact acacatctaa atcaaatcta aatttctgta tcaatgaaaa
    59701 ttatgataaa ttggtaggaa gactcaatga caatatagct agtaatcctg aagaagacga
    59761 tgaagctctg ttgggctcaa gaattgacat gtcagatatt ttcaagcata tttcggttgt
    59821 ttatgttgac gctcttcgag atgttcttag agaaatgaaa aacaatcgaa acccagtcaa
    59881 aagaatcatg gaaacaattg aatcaaaaat atcatcagat aatgttgagt cattaaaaac
    59941 aattatacag caattaaatg agactattac cagtgttcct gaaattagga aaattggcga
    60001 aaatattaat cggcaactaa atagcataat tggttcagtg tattctccta atcttcttct
    60061 ttcctcaact atgtcagatg atatgggttc tttagcaaaa tttctttcaa tgaagccaga
    60121 acaaaatatc gacttagact tactagggtt aggacatcta aatatgattt atttagcttt
    60181 gaaaatagtc gaatttgaag cgtgtcgttc aagagaacta cttaatatta tgttgattga
    60241 agaaccagaa gctcatattc atcatcatat tcaaaaaact ctgttcgaag gattaaatct
    60301 tcaaaaaaac tatactcaga ttctcatgac cacacattct gtacatttag ctgaagtgtc
    60361 tgaaatatct cggatgaatg tattaaaatc gtttaatggc aaatctatcg ttatgaatcc
    60421 agcaaataat ctgaactcat ttgctaaaga aaagttaaaa aagaacaatc taaatctaat
    60481 aaacgcagta gagagatatt tagatgttaa aagaaatgga ttgctttttt ctaaaggtgt
    60541 tatcttagtt gaaggagatg ctgaagaaat acttattcct caaatagtaa aaaaattatt
    60601 tggtataaac ttagacgaac ttggaatagg tttgattaat gttggtagta cttcgtttga
    60661 atatatcgct agcttgtttg acgatgatag aatacagaga aagtgtgcta ttgtaactga
    60721 tttagatgaa caggcaatcc catcagaaca tcgattgtat aaaagcactg cacaagagaa
    60781 aggtcaagca agaaaagaaa aattatcctc cctttttaat gaaaacaatt gggttaattg
    60841 tttttatgct aatacaacat ttgaaattga gtttttagat gtgaataaag aaaatattct
    60901 aacttatgtc agtccaatta tagatgacgc attcaaagat aaaaaaacaa taactgctta
    60961 taaagaagaa atacaaagtg aacaatattt agaaagaaat ttagcgatgt taaaactagc
    61021 caatcatgtt ggtaaggggt ggtttgcaat tgagttaggt gaaaaaattg actttttaat
    61081 caaaattcct aagtatattc ttaatgctat tgcttttgca tgtcaggaaa tagtagatct
    61141 ctcaatttat aaaaaaattc tactccatac aatcgacttg tacgaggaaa ctacagaatt
    61201 gtcagcttta tcagctagtt taaaaacaag tgatacagct gatttgaata tagcaataat
    61261 ttctttatta gagtactttg gtaaagatga ggatgttgtg tatctaatca atcagataga
    61321 aaattacaca aaaatacttt atgctgaggt ttcaaaatga caaatatctt cgaaaaaatc
    61381 gtaaatgatt taaatttaga acaaaaagat gttgtggaaa gtgaagataa cctttatgta
    61441 aatgcatgtc ctgggagtgg gaaaacaagg gtacttacaa ggaaaattgc ttaccaagca
    61501 attaaacacg atggatcact aaaaagaata attgctatca catacactaa tagagctgct
    61561 gaagaaatta aggaacgcct aagtttactt agtatagatg atgatattaa tatttgggtg
    61621 gggacaatac atcagttttg tcttgaattt attatttatc cttttaaaat gaatctctca
    61681 agagtatcaa aaggatttac aattattgat gattatactc aaagagctta cgtcagccaa
    61741 attaataata tgctgaattt aaatctcaaa acgtatgaac tgaacaaaat tgatttgtca
    61801 ctttctcatg attttaaaat taatgaagtt cagtatactc aagtttctga aatgtatcac
    61861 actatgttgg aaaaaaataa agaaattgat tttgatatga ttttactagt agcgtataaa
    61921 attttaactg taaacagtaa cgttgcacgt aatattgcta gtaatataag ggcgatttat
    61981 gtggatgaat ttcaagatac tagagaatta caatacaatg taatagctaa attacttcaa
    62041 aacaaccctc aaattcagtc aatgtttgtt ggagatattg accaagcaat ttatggatca
    62101 ttagatggta tagctaaatc agttgaagaa ctagaaatgc taactagtca cacttttcaa
    62161 tcaaagacgc tacatggctg ttacaggtct aatcagagat tagtagactt ctactctaat
    62221 tttcagagtt gtccttacga gattgaaagc agagggaata ataaaaacga ccgtggtttt
    62281 ataagttatg attgcaaagt tactaaggag gatttaccca acataataaa aaatataata
    62341 aaggaaaaga ttgaaagcgg cattcatgaa aaagatattt gtgtacttgc tcctcaacac
    62401 tatcctctgt tttcactggg tgagtattta aagaaagaat taccgtattg caattttgat
    62461 gctataaata tatcaccaat taaggtaaat aatcatagtt tatttttcaa gttagcaatt
    62521 ttgtacttta ctgaatcagg tgaaaaggtt cgaagaagaa agctaattgc aaacgatatt
    62581 ttaattatat taaaaaatga atttggaata gaagttaaag attattttat tgacttagat
    62641 ttattacagc taataaacag tgtgaaaaga atgtatagtg gagacgacaa cggtgttgat
    62701 ttatacaaat ttgttaccaa acatatattt gttaatctta atattgacga gaaaaattac
    62761 ccgtctattt ttaagcacta tctatttttt attaacgaag tagaagatcg gataaaaaat
    62821 aattcattat ctagtagtgt atctagtttt aagaagatgt ttaaatctcg agatggtatc
    62881 acacttacta cagcacataa agttaaagga aatgagtatg atactgttat cgctattaat
    62941 cttctaaacg ggaaaattcc tcattggaat gaaattttta atgtttctga taaaggaatt
    63001 agttcagcga gaaaactact atacgtaatt tgttcaagag caaaaaataa tttatttctt
    63061 ttctcagagg tgggttattt tacgagtaaa ggagacttgc tttatcccac tcaattatta
    63121 gataaaatag aatttgatta taatatttaa aatacctagg tagtcgttgt tttaaatata
    63181 gtaggaatcg gacgctcagt acggagcgtc tattttttta cccaattttg aaaggaagtg
    63241 aacttatgaa aataaaaaat caagaatcaa aaggtcgctc tccccccttt aaaaccatca
    63301 cacaaataag attcattcaa acataaaaac agaaaggata ggtaaaaata tggaacttaa
    63361 atatgtcatt cccaatatgg aaaaaacatt tggacaatta gaatatgctg gtgaagggaa
    63421 cattgaacaa cgtcgaataa atggcagacc aaccattctc tctcgtagtt acaatttata
    63481 ctcaacgatt caacgagcag atgatattgt tgtcattctt ccctccgaag ctggcgagaa
    63541 acattttgaa tccgacgaaa aagtcaaact catcaaccca catattaccg cagaaggtta
    63601 taaaattggc aatcgaggat ttaccaatta cattatgcac gcagacgata tggtgaaagc
    63661 ataagaaagg aaaggtgaaa aaatatgaga ttagcagaag gtattgtgat tgaaaaagac
    63721 cagacatttg gcacattgaa attttccgcc ttgcgtcgtg aggttcgtat ccagaatgaa
    63781 gatggtacgg tttccgaaga aattaaagaa cgtacctatg acttaaaatc aaaaggacaa
    63841 ggacgcatga tacaagtcag tatccccgct tctgttcctt tgaaagaatt tgactacaac
    63901 gcagaagtgg aattaatcaa tcctgtggca gataccgtag cgacggctac ttttcgaggg
    63961 gcagacgttg attggtacgt gaaagcagac gatcttgtat taaaaggaca gacaaaacct
    64021 catcagaaat ataaaaaaga agcgtccgaa agtgaaaaat aggtgttgct tatgacaaac
    64081 acaccattga ttttgaaaga aattccgaag gatgaagcca tttcttttat tcggcaatac
    64141 cattattcaa agatactccc tagattgtgt aaatactttc tagggatttt ttcagaagaa
    64201 aaattattag gcgttgtgga attaggctgg ggtacgcaac ccctacaaac catacgcaaa
    64261 ctctttcccg acagttccct tcaaaccaca gattatttag aaattggaaa gatgtgtttt
    64321 cttccagaaa tgaatcaaac caattatttt ggcagtcaag ctctttcagc tctaattaag
    64381 tggttgaaag aacatacgga ctgtcatttt ttatatacac tggcagatgg aattgaggga
    64441 aaatgtggct atgtctatca agcgtccaac ttcttttact gcgggtattt caagacaagt
    64501 gtctatcgtg ataagcagtc atgggaaaag atacaccctc gaagtgctcg ccttttatta
    64561 gaggaaaatg ctcgctttga acaggtagag aaaaagcatt ggctttccca ggcattttgc
    64621 gaatacaaag ggattgagaa aatcaatgga cgcatgtttc gctatctcta tccgttgaca
    64681 aaagaagcga aaaaactgtt aggacacact ctctatcgac gtcattatta tccgaaagaa
    64741 aaaaatttac gctttgaaaa gcgaatcgct tatcagaaat atgaagccat ttctcaacca
    64801 acttttgata aacaggctcg tatctacaat acacaattat tttgataggt ggaaaggagg
    64861 atttttatgc cattgcttca tgacagagga gagcgaatca aagccaacga taagcacttg
    64921 gtctatcatt ttgtactaat ttcattgctg gtagtttttc tagtcgtcct actccctttt
    64981 cattggagag cgttacaatc ggtgaactgg caagcagttc agttagatac atttttctat
    65041 caacttcata cgccatactt ttggagcagt attctcactg ctctttttgt atgcggactt
    65101 atcagctggc tttattatca ctatcgtata gattctataa aacagttaga gcaccgtcaa
    65161 aagttagctc gtatgatttt agaaaatcat tggtatgaag ccgaagaaac tcaatcagag
    65221 ggattcttta aagatttacc cagcaagaaa accaaacaac gaatccgcca ttttcctaaa
    65281 atatattatc gaatgaaaga tggactaatc catattcatg tagaaatcac cttagggaaa
    65341 tatcaagatc agcttttgca cctagaaaac aaactagaaa caggattgta ttgtgaatta
    65401 gtggaaaaaa cgttgaaaga ttcttatgta gagtatgtcc tactttatga tactattggc
    65461 aatcgaattg gcattgaaga cgtggtagct caagatggac gtgtcaaatt gatggaatcg
    65521 gtctattggg agttcgattc tctccctcac atgttaattg ctgggggcac tggtagtgga
    65581 aaatcctatt ttattctcac attgattgaa tctctcctgc atacaaatgc aaagctttat
    65641 attcttgacc ctaaaaatgc tgatttggca gacttagggg cggtcatgaa taatgtctat
    65701 taccgtaaag aagatatgtt ggcatgtatc aatcaatttt acgaagatat gattgatcgc
    65761 agtgaaacca tgaaacaaca ccctaactat aaaacaggag aaaattatgc ttatcttggt
    65821 ttgtctgcca attttcttat ttttgatgaa tatgtggcaa tgatggatat gctaggtcgt
    65881 gaaagtacca ccgttattca taaactcaaa caaattgtaa tgttaggacg acaagcaggc
    65941 ttctttttaa ttcttgcctg tcaacgtcca gacgcaaaat attttagtga tgggattcgg
    66001 gacaacttta acttccgtgt ggctttgggt cgtatgtctg aaatgggctt tggtatgatg
    66061 ttcggaagcg atacacaaaa acaatttttc ttaaaaccca tcaagggaag aggttacgtg
    66121 gatacaggaa aaagtgtgat tagtgagttt tatacacccc ttgtaccaaa aaggtacgat
    66181 ttcttaggag aaataggaaa agtcattcaa aaaaagcaat ctgagcctgt accgcacgaa
    66241 gtgaaaggta caggttcaga cttgctttga ttggtgtggc gttagccacg ccaatccttt
    66301 agccccctct atctaacagg ggggcacaaa tacaactgaa aacaggcaat tctcatcaac
    66361 caatgttgat ggtacaaagg attgcggaaa atatgaaagg tgtaaactca agggtcatag
    66421 tttacatctt ttttagattg gaggtttgcg aatggaaaac gaaaaaattt ggattaagga
    66481 attgaaagaa aagcgactgg cttatggcgt ttctcaaaat aaactggcgg ttgcttctca
    66541 tattaccaga ccttacctat cggatattga aacaggcaag gcagtcccta ctcaacaggt
    66601 gaaagaagat ttactgaacg ctttggaacg cttcaatccc gataacccat tggagatgtt
    66661 attcgactat gtacggattc gattccctac caatgatgtg gctcaaatta tcggtgaggt
    66721 tttacgtttg aatatggatt atatgctaca cgaagacttt ggctattatt cttatcccga
    66781 acactatcgt ttcggtgata ttgttgtcct agtctctcat gatgtaagta aaggtgtttt
    66841 attagaactg aaaggaaaag gctgtcggca atttgaaaac tttctattgg ctcaacatcg
    66901 gagctggtat gatttctttc aagattgcat ggaacataaa ggtattttca aacgcttgga
    66961 tttagctatc aacgataaaa cagggatttt gaatattcca gatttggcaa agaaatgtaa
    67021 acaggaagaa tgcatttccg tctttcgaag ctttaaaaat tatcgcagtg gtgaattggt
    67081 tcaccgtgat gaaaaaccat acatgggaaa cacactttat attggctcat taaaaagtga
    67141 agtctatttc tgtatatatg agaaagatta tgagcaatac gtgaaaaatg atgttccctt
    67201 agaagacgca gaagtaaaga atcggtttga aattcggtta aaaaatgacc gagccaccca
    67261 agccatgaaa gatttattgg cacatcaaca ggcggaaaaa acagcctttg aaattatcaa
    67321 tcgctatatc cgctttgcag ataaagacga cactaaacgt cggagtgatt ggaaaactaa
    67381 tgaacgttgg gaatggttta tcggtaaaaa tcgtggagca ttacgcctaa ccacacagcc
    67441 agagccttat tcttttgaac gaacattgaa ctggttacat catcaagtcg cccctacatt
    67501 aaaaatcgca agcattttag atgttctcaa cggtacaacc attatctcca ccatgattca
    67561 ggaagccaaa ctgacagaaa aacatgagaa attaattgaa caacaacatc tagccatgga
    67621 ggatttgatt acatgagcct tttaacaaaa gaattaaaga agttagggtt tcagtgtggc
    67681 attgagtttc aagcgtatat acaaaataca gggaaatata cgtctctcat tattgaggga
    67741 aaacggcaag ctggtgatac catctatacc tatgattttt acaaggtgag attttataat
    67801 aattatacca atcgagtaac cgtctatgga gagcatttaa ccccttttca attattaagg
    67861 cgtgtaaaaa gctatatcta ttatcgagaa aaatatctta aggaaaggag gacaatcaca
    67921 tgaattttgg gcagaatttg tacaactggt tcttggataa tgcacagtca ttggtattgt
    67981 tagcgattgt tgtcattgga ctgtttttag gttttaaacg agaattttca aaactcattg
    68041 gcttcttgat tattgctcta atcgccgtcg gacttgtgtt caatgcagct ggcgtgaaag
    68101 atgtgttatt aaacttattt aaccgaatca ttggtgctta acagatattt ttcatgataa
    68161 aataggaagt atatattttg ttatgaaagg atttatgaat atgtttacaa atgatcaatt
    68221 taaatctctt ttaattaaaa cattagaaag aaagagctct tcaaattatt atgaaggagg
    68281 taacgagatt gtttctaaaa tgaaaatatc agaggtaact ttagatgaga ctgacgattt
    68341 tacttattat aaaggatata aaaagggctg gaatacgctt tgcacatatc ttaaaataag
    68401 agttcctttt gatgatttag acttttttga aagtcataaa gatttgatta cccagacagc
    68461 aagctccata tatgataaac aaggtgataa tgtattagtg gatactattt tagtaccact
    68521 tccagagaat tacgaagtaa ttaactttag tcagttgaaa attagtgatg tggtttcaca
    68581 agctattgaa gacgctgagt cttttatgag taatggtgaa tatcaacgtg cctttgacag
    68641 agttcacact gcttttcatg gatatttaat tgaaatacta aaaaaatatg aaattacagt
    68701 tcctagagac gaaaatctat ctaaattata tagtaggata caacaattaa ttgaaaaaga
    68761 aattcaacct actgaacttg ctgatatagt gaagacaacg ataaggtcat caaatggaat
    68821 gattagctct cttaatgaag caagaaatag gcattcactt gcacacccta atacaaatat
    68881 tattggaaag agagaagcaa aactaataat aggtatttca agtacagtta cagattatat
    68941 tagcggatac cttgataagt agcgtcatta actgattgct acttttttta tgactatttt
    69001 tataaaaagg atgtgataag aattggaaat gaaagtctat gtggcaaatt taggacggta
    69061 taatgaaggt gaattagtcg gagcatggtt tactccacca attgatgagg aagaaatggc
    69121 agaaagaatc ggtttaaatg aggactacga agaatatgca atacatgatt ttgagcttcc
    69181 ttttgatgtg gacgaataca cgccgattag tgaaatcaac cgtctatgtg aagccattca
    69241 agaaatcgaa ggtacaccta tttataatga actcaaagaa attcaaggca tgtggtttag
    69301 tagcttggaa gaattactgg aaaacaaaga ggatattcat tgttatagtg attgtgattc
    69361 gatggaagat gtcgcccgtt attacgtgga agaaacagga cagcttggtg aagtcccttc
    69421 caatttacaa aattatattg actaccaatc tttgggacgt gatatggaaa tagagggtaa
    69481 ttacctagtt acctctcatg gggtatttga atattgtcag taagtttaac aatccgtgtt
    69541 ataattaaat taataaatag cacggagagg tataaattat ggtaaatgta tttgaaaatc
    69601 ttaaactatt aaaactagac atgaaagata aaggctgggt gatagattcc ttttactttc
    69661 gttacaaaca gcaaaattat attgtacttg ttaagctatt tgaaaaagag gaaaaagttc
    69721 cagaatatgc tctgttaaaa ctagaatttt taaaggaaaa cgatttttca gatatgctag
    69781 ctgtctatgc taattcggta aaattatata cagacacgaa aacaataaga gaatattttg
    69841 gtatcgaata cagtagtaac ttgggagatg ttttatttca atttagccaa actcttgctc
    69901 gatttattcc gacagaagtt agtgagaaga aaaatgaaga ccaaaaagaa gccatgtgtt
    69961 tctcattaag tcaaagtgat tcagaagatc ccagaaaaaa atattgtttt tcagttagaa
    70021 gaaatccttt aaagggaaat ggtgagctgg gaaaacgaag tccttttaat gacaataaaa
    70081 cgagattgta tagacccagc ttatatgaac gattagggtc agataccaat ttaagtttca
    70141 gatattcaat gaatccagat gatgaagaaa ctgatgaagg tattattgca aaatggacaa
    70201 aaaataaaat tgaatagtta aagcattgaa agagcaatca cctattttga ttgttctttt
    70261 tctattttta cggaaaggac gtgaagacat gaaaaaaata agaagttaca ccagtatttg
    70321 gtcagtagaa aaagtgattt atgcgattaa tgatttacaa ctccctttcc caattacctt
    70381 tacgcaaatg acatggttta tcgtttcttt gtttgtcgtc atactctttg gcagtttacc
    70441 accactttct ctgattgacg gagcactact caaatactta gggattccca ttgttctcac
    70501 tgggttcatg tgccaaaaga cctttgacgg aaagaaaccc tatggatttc taaagtctat
    70561 cattacctat gctctacgcc ctaaagtaac ctacgctggc aaacaaatac gattaaaaaa
    70621 agaaacaatg aatgaatcga ttacgattgt aaggagtgaa caactagatg gcatatccga
    70681 ttaaatatat ggaagataat ctcgtattta atcatgatgg cgaagtattc gcttattatg
    70741 aattaattcc ctataattac agttttttaa gttccgatga aaaaattcaa gttcatgata
    70801 atttctgtca attgattgcc caaaatcgtg atggcaagat tcatgctctg caactagcaa
    70861 ccgaatcaag tattcgagcc acacaggaac aatcgaaaaa agaaatcact ggacgattaa
    70921 aagagatagc ttacgaaaaa atagatgaac agaccgaagc gttaatttct atgattggtg
    70981 acaatcaagt agactatcgc ttttttattg gttttaaact ctacctcaat gaacaggaag
    71041 tatccgtaaa aaatgttggg aaagaaattc aaaaagcatt tgcggaattc tttcatggtg
    71101 tgaatcacaa attaatgggc gattttgttt ctatgcctat ggcggaaatc gaacgctttt
    71161 ctaagatgga acagttgtta gaaagtaaat tatccagacg ctttcagatt cgtaaattgg
    71221 agaaagatga ttttggttat attattgaac atctttacgg gcaaacaggt gtcccttttg
    71281 atgactacga ctaccattta ccgaaacgat acgaagataa aaaagtgttg gtaaagaaat
    71341 acgatattct caaacccact cgctgtttaa tcgaagaaaa tcaacgctat ttacggattg
    71401 aacaggaaga taccactact tatgtggcgt attttacaat taatagtatt gttggtgaat
    71461 tggatttccc taatagtgaa attttttatt accagcaaca gcagtttact ttccccgttg
    71521 ataccagtat gaatgttgaa attgtcgcca ataaaaaagc cttatctacc gttcgcaata
    71581 aaaagaaaga actgaaagat ttagatagcc acgcatggga aagcgacaac gaaaccagta
    71641 ctaatgtggt ggacgcttta gaatctgtcg atgaattaga aagtaattta gaccaaacca
    71701 aagaatctat gtacaaacta agctatgtgg tacgggtatc agcaaagaat ttggacgagc
    71761 tgaaacaacg ttgtgatgaa gtaaaagatt tttatgatga tctgtctatc aaattagtac
    71821 gaccttttgg cgatatgcta ggcttgcata atgaatttat tccctcaagc aagcgatata
    71881 tcaatgacta tattcaatat gtcacgtcgg attttttggc tggtcttggt ttcggtgcta
    71941 cacaaatgat tggtgaaaat tctggtattt acgtcggtta caatctcgat acaggcagaa
    72001 atatttatct ccaacctagc cttgcaagtc aaggaattaa aggctctgta acaaatgcat
    72061 tagcgtccgc ttttattggt tcattaggtg gcggaaaatc attctctaac aatatgctgg
    72121 tctattattc agtactcttt ggcggacagg caaccattgt tgacccaaaa gc
//
LOCUS       DAFEKH010000007        68687 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.007, whole genome shotgun sequence.
ACCESSION   DAFEKH010000007
VERSION     DAFEKH010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 68687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68687
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.007"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(594..1985)
                     /locus_tag="LP386_000533"
     CDS             complement(594..1985)
                     /locus_tag="LP386_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HBL1917795.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            complement(2198..2584)
                     /locus_tag="LP386_000534"
     CDS             complement(2198..2584)
                     /locus_tag="LP386_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HBL1917796.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            complement(2640..3263)
                     /locus_tag="LP386_000535"
     CDS             complement(2640..3263)
                     /locus_tag="LP386_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HBL1917797.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            complement(3327..3995)
                     /locus_tag="LP386_000536"
     CDS             complement(3327..3995)
                     /locus_tag="LP386_000536"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBL1917798.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            complement(4007..4447)
                     /locus_tag="LP386_000537"
     CDS             complement(4007..4447)
                     /locus_tag="LP386_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917799.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            complement(4506..5177)
                     /locus_tag="LP386_000538"
     CDS             complement(4506..5177)
                     /locus_tag="LP386_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917800.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFLKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            complement(5362..5760)
                     /locus_tag="LP386_000539"
     CDS             complement(5362..5760)
                     /locus_tag="LP386_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HBL1917801.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(5757..6530)
                     /locus_tag="LP386_000540"
     CDS             complement(5757..6530)
                     /locus_tag="LP386_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBL1917802.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(6527..7210)
                     /locus_tag="LP386_000541"
     CDS             complement(6527..7210)
                     /locus_tag="LP386_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBL1917803.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(7377..8264)
                     /locus_tag="LP386_000542"
     CDS             complement(7377..8264)
                     /locus_tag="LP386_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL1917804.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(8261..9130)
                     /locus_tag="LP386_000543"
     CDS             complement(8261..9130)
                     /locus_tag="LP386_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1917805.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(9267..10553)
                     /locus_tag="LP386_000544"
     CDS             complement(9267..10553)
                     /locus_tag="LP386_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL1917806.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            10826..11404
                     /locus_tag="LP386_000545"
     CDS             10826..11404
                     /locus_tag="LP386_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBL1917807.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            11404..12333
                     /locus_tag="LP386_000546"
     CDS             11404..12333
                     /locus_tag="LP386_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1917808.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            12330..14066
                     /locus_tag="LP386_000547"
     CDS             12330..14066
                     /locus_tag="LP386_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBL1917809.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(14129..14965)
                     /gene="pheA"
                     /locus_tag="LP386_000548"
     CDS             complement(14129..14965)
                     /gene="pheA"
                     /locus_tag="LP386_000548"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HBL1917810.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(14962..15471)
                     /locus_tag="LP386_000549"
     CDS             complement(14962..15471)
                     /locus_tag="LP386_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HBL1917811.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(15464..16759)
                     /gene="aroA"
                     /locus_tag="LP386_000550"
     CDS             complement(15464..16759)
                     /gene="aroA"
                     /locus_tag="LP386_000550"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBL1917812.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(16772..17863)
                     /locus_tag="LP386_000551"
     CDS             complement(16772..17863)
                     /locus_tag="LP386_000551"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HBL1917813.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(17880..19046)
                     /gene="aroC"
                     /locus_tag="LP386_000552"
     CDS             complement(17880..19046)
                     /gene="aroC"
                     /locus_tag="LP386_000552"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HBL1917814.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(19048..20112)
                     /gene="aroB"
                     /locus_tag="LP386_000553"
     CDS             complement(19048..20112)
                     /gene="aroB"
                     /locus_tag="LP386_000553"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HBL1917815.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(20145..21167)
                     /gene="aroF"
                     /locus_tag="LP386_000554"
     CDS             complement(20145..21167)
                     /gene="aroF"
                     /locus_tag="LP386_000554"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBL1917816.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(21826..22800)
                     /locus_tag="LP386_000555"
     CDS             complement(21826..22800)
                     /locus_tag="LP386_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HBL1917817.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(22781..24664)
                     /locus_tag="LP386_000556"
     CDS             complement(22781..24664)
                     /locus_tag="LP386_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HBL1917818.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(24682..26907)
                     /locus_tag="LP386_000557"
     CDS             complement(24682..26907)
                     /locus_tag="LP386_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBL1917819.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEEKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            27022..28056
                     /locus_tag="LP386_000558"
     CDS             27022..28056
                     /locus_tag="LP386_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1917820.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(28123..29136)
                     /locus_tag="LP386_000559"
     CDS             complement(28123..29136)
                     /locus_tag="LP386_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL1917821.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKHLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(29214..29402)
                     /locus_tag="LP386_000560"
     CDS             complement(29214..29402)
                     /locus_tag="LP386_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HBL1917822.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(29842..29970)
                     /locus_tag="LP386_000561"
     CDS             complement(29842..29970)
                     /locus_tag="LP386_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBL1917823.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(29973..31346)
                     /gene="rlmD"
                     /locus_tag="LP386_000562"
     CDS             complement(29973..31346)
                     /gene="rlmD"
                     /locus_tag="LP386_000562"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBL1917824.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(31457..32512)
                     /locus_tag="LP386_000563"
     CDS             complement(31457..32512)
                     /locus_tag="LP386_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBL1917825.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(32522..33952)
                     /gene="gatB"
                     /locus_tag="LP386_000564"
     CDS             complement(32522..33952)
                     /gene="gatB"
                     /locus_tag="LP386_000564"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HBL1917826.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(33949..35421)
                     /gene="gatA"
                     /locus_tag="LP386_000565"
     CDS             complement(33949..35421)
                     /gene="gatA"
                     /locus_tag="LP386_000565"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HBL1917827.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(35421..35726)
                     /gene="gatC"
                     /locus_tag="LP386_000566"
     CDS             complement(35421..35726)
                     /gene="gatC"
                     /locus_tag="LP386_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HBL1917828.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(35832..37868)
                     /gene="ligA"
                     /locus_tag="LP386_000567"
     CDS             complement(35832..37868)
                     /gene="ligA"
                     /locus_tag="LP386_000567"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HBL1917829.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(37885..40119)
                     /gene="pcrA"
                     /locus_tag="LP386_000568"
     CDS             complement(37885..40119)
                     /gene="pcrA"
                     /locus_tag="LP386_000568"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HBL1917830.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            40274..41833
                     /locus_tag="LP386_000569"
     CDS             40274..41833
                     /locus_tag="LP386_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HBL1917831.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVVGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(41944..43875)
                     /locus_tag="LP386_000570"
     CDS             complement(41944..43875)
                     /locus_tag="LP386_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL1917832.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(43893..44807)
                     /gene="pfkB"
                     /locus_tag="LP386_000571"
     CDS             complement(43893..44807)
                     /gene="pfkB"
                     /locus_tag="LP386_000571"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBL1917833.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSETETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(44804..45556)
                     /locus_tag="LP386_000572"
     CDS             complement(44804..45556)
                     /locus_tag="LP386_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBL1917834.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(45715..45924)
                     /locus_tag="LP386_000573"
     CDS             complement(45715..45924)
                     /locus_tag="LP386_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917835.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(45935..47263)
                     /locus_tag="LP386_000574"
     CDS             complement(45935..47263)
                     /locus_tag="LP386_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917836.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            47399..47554
                     /locus_tag="LP386_000575"
     CDS             47399..47554
                     /locus_tag="LP386_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917837.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(47628..48215)
                     /locus_tag="LP386_000576"
     CDS             complement(47628..48215)
                     /locus_tag="LP386_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HBL1917838.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(48298..49548)
                     /gene="clpX"
                     /locus_tag="LP386_000577"
     CDS             complement(48298..49548)
                     /gene="clpX"
                     /locus_tag="LP386_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HBL1917839.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(49795..51084)
                     /locus_tag="LP386_000578"
     CDS             complement(49795..51084)
                     /locus_tag="LP386_000578"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HBL1917840.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(51238..52170)
                     /locus_tag="LP386_000579"
     CDS             complement(51238..52170)
                     /locus_tag="LP386_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917841.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(52327..52986)
                     /locus_tag="LP386_000580"
     CDS             complement(52327..52986)
                     /locus_tag="LP386_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBL1917842.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(52989..54014)
                     /gene="sppA"
                     /locus_tag="LP386_000581"
     CDS             complement(52989..54014)
                     /gene="sppA"
                     /locus_tag="LP386_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HBL1917843.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(54027..54317)
                     /locus_tag="LP386_000582"
     CDS             complement(54027..54317)
                     /locus_tag="LP386_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917844.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            54726..56531
                     /gene="glmS"
                     /locus_tag="LP386_000583"
     CDS             54726..56531
                     /gene="glmS"
                     /locus_tag="LP386_000583"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HBL1917845.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(56603..57958)
                     /locus_tag="LP386_000584"
     CDS             complement(56603..57958)
                     /locus_tag="LP386_000584"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HBL1917846.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(57982..59151)
                     /locus_tag="LP386_000585"
     CDS             complement(57982..59151)
                     /locus_tag="LP386_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917847.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(59148..60035)
                     /locus_tag="LP386_000586"
     CDS             complement(59148..60035)
                     /locus_tag="LP386_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HBL1917848.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(60224..63916)
                     /gene="nifJ"
                     /locus_tag="LP386_000587"
     CDS             complement(60224..63916)
                     /gene="nifJ"
                     /locus_tag="LP386_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HBL1917849.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            64115..64636
                     /locus_tag="LP386_000588"
     CDS             64115..64636
                     /locus_tag="LP386_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBL1917850.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(65335..65892)
                     /locus_tag="LP386_000589"
     CDS             complement(65335..65892)
                     /locus_tag="LP386_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917851.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(66071..66682)
                     /locus_tag="LP386_000590"
     CDS             complement(66071..66682)
                     /locus_tag="LP386_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917852.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSAQYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            complement(66795..67052)
                     /locus_tag="LP386_000591"
     CDS             complement(66795..67052)
                     /locus_tag="LP386_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917853.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            complement(67649..67927)
                     /locus_tag="LP386_000592"
     CDS             complement(67649..67927)
                     /locus_tag="LP386_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917854.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKK"
     gene            complement(67961..68212)
                     /locus_tag="LP386_000593"
     CDS             complement(67961..68212)
                     /locus_tag="LP386_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917855.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
BASE COUNT        19206 a        14834 c        12081 g        22566 t
ORIGIN      
        1 atctgttcta acattctcaa ctttgtcagt ttaccatagg aaaatgggaa aatctacgaa
       61 agctctcaac agaatcgtcc tacttaaata cgcttttctt taataataaa taagttggtt
      121 gtttttgtta tttgcgcttt cacttttcgg aataaataat gtgtatttat atggaataaa
      181 taaaaaaaga ggtcgtgact aaaaacaagt cacaacctct ggtaaacggt gttctcctga
      241 caactcctcg gtcacaagac acaatattca acaaacatga gaagctattt tttgaaattg
      301 ctctttgtga ctcagagtga aacggcaggc tcacgacctc tttcttaaac ggtgttcaaa
      361 agcttgcatc tgcggtaata agctcaacca aacgtaaaat atgaggaact atttttgttt
      421 ggctgttctt attacttgat gcagggcagc tttttcacaa cctcttattc acggtgtttc
      481 agaagtagct tctcggaaat aagccgaaat ttcacaaaaa tttgagaaac tatttttagg
      541 aaacttcttc ttatttctta aagctgacca cttctatcac aacctctttt tgactatgca
      601 ttcacatcga tcactttaga atcatcattg atgacatcgc gatctaaatc tttgatgcgt
      661 gcacttgtca cgataccagc taccatgcta ccgctgacgt ttactgctgt acgtgccata
      721 tcgattaatg gttcaacaga gataactaac ccaacgattg ctactggcaa gttcattgcc
      781 cctaaaacga tcagtgaagc aaatgttgcg cccccaccga ctccagctac accaaaagaa
      841 ctgattgtta caattgccac aagcatcaaa ataaattcca aactaaagac attcactcca
      901 gctgctggtg cgacgatcgt tgccaacata gctggataaa cgccagcaca gccgttttgt
      961 ccaatagaca aaccaaaact tgctgagaaa ttagctgttg catcatctac tcctaaagct
     1021 tttgtctgag tctcgatatt caatggcaaa gctccagcac ttgaacgtga agtaaacgca
     1081 aagctcaata ccggaaaggc ttttttgaaa tagttgattg gattgacttt tgcaccaatc
     1141 aaaatcagtg agtggacaat caaaacagca agcaatgcta cgtaagaagc aacgacaaat
     1201 ttacctaaat tgacgatagc tgcaaaatca cttgttgcca aaacgtttgt catcaaagca
     1261 aatactccat aaggtgtcaa acgcaaaaca agcgtcacga tccgcataat gattttatac
     1321 agactgtcga ctaaatctga aaagaatgct gcttcttttg gcgcttttct tttcacgcct
     1381 agataagcga ttccgacaaa tgccgcgaaa ataacgactc caatcgtact tgttgcacga
     1441 ctacctgcta aatcagcaaa aacgttttta gggataaagg ataaaatctg ctgtggaatc
     1501 gataagtttt caactgtttc ctgacgtgtt gccagttcag agattcgtgc tgtttctgca
     1561 gctccttgtg tgaatttagc tccttggagt ccgaacagca ttgttgaacc aattccgatc
     1621 aatgctgcaa tagctgttgt tccaagtaaa gaagtcaata cagtcgcact aattttccct
     1681 agcttttcag aaactttcat ttttgtgaat gcaccaatga tcgaaataaa cactaaaggc
     1741 ataactagca tttgcaagaa tgatacatat ccttgaccta caatcccgat ccattccatt
     1801 gattgagtaa cgactttgtc gtctacacca aagatcaatt gaagcagacc gccaaagacg
     1861 ataccaactc ctaatgctgt aaagacgcgt gttgaaaatt ttgtatggcg cttttgcata
     1921 cgatagaaca catataataa tgccgcaaaa actagaacca ctaaaactgt gatgagtgtt
     1981 gtcatttttc tcctcctcat attattaatg acaagtccat cgaaggaagt aaaggttccc
     2041 gagaatgatt cttcaaccat cctcctgaaa aaattttttt cagtgacttt tatattttag
     2101 acgattttta tcgaaatgac attctttttg cttacaatta gtaataaaaa aacatacctg
     2161 tgatagcttt aatctatcgc aggtatgttt ttactgtcta ttcttgtttt tctgattgaa
     2221 aattcaattt taccccaggc tgatctaagg cgatctctgt cacctcataa gacattcggc
     2281 gtacgatatc gaataacggt gctactagct cgtccacttc ttcttgtgtg acatcatttt
     2341 gaccttcaat tttccgattg aggatatgat tgatctgact cacacttcca gataaaacat
     2401 atgtatcaaa cactaaacgg aactctaagc gtgctcctac gatgctatgt tctttcggat
     2461 agttttcgat cgtttctttt aaaggcgaga agcctacttt caaatctgtt tctacttctt
     2521 ggttcggcaa tctcatatca taatgaaatg cttctacaac ttctttttgt cttctgattt
     2581 ccatataatt ttatcactcc tttatgaaaa ttataacata tctcctttga aaggggatac
     2641 tactttttaa tgatgctctg caaggtaagg atttcattca gatttcctac cacataatct
     2701 gccgggatct cacccagaaa atgatcgatg tcgtaaagac aagtagcgac tcctgcattt
     2761 ttccctgctt cgatatctaa acgacgatcg ccgatcatca tcgtgtctgt tctttctaaa
     2821 tgaaaagtat cgatcaaata atttaaagat gctggatcag gtttacgagg aaagtcctga
     2881 tcgatcccta ctacttcctc aatcagatgt gccaatcgat gttcttttaa caggccccat
     2941 gttgattctg tcaaacggtg ggtcaggatg aaatgacgac cgccgttgtc ttttagcatt
     3001 tccagtactt gtttcgtttc tggaaatgga cgggaaactt ccgtactttc tttttcatat
     3061 cggtgaaata attcattaaa ctctctggca ttcaagtttg attcattgat caaataacta
     3121 gtagaatact ttttcatttt gaagtagatt tcttttttgt ccatactgat accaaaatct
     3181 tttagtgctt gccatgcacc atctaccatt gcgggatacg tatcaaacaa tgtaccatca
     3241 aagtcccata tataattttt catgttcctt ttgttccatt cctttgcttc ttttttctat
     3301 ctctcacttt tagataaagg tgttctttaa agtatttttt tgtccagaat tgtcaaatca
     3361 tctgctaatg tatactggat tggttgtgca tttgggatat cgatcgtatc catttgatct
     3421 tcaggaacat cttctaaata ttttgtcagt gctcggatgc tattaccatg acccacaact
     3481 agtaaatctt gccgatcttt tagttttggt gctagatgat cttgccataa gggaatgatc
     3541 cgattcactg tcatttccag actttctccg tatgggatca aatgcggatc caagtgatca
     3601 tatctgcggt caaatctatt ttctgcggtt aacggcggaa cttccgtata tcctctgcgc
     3661 catgttttta cttgatcttt tccgtatatt tctttcatct tatctttgtt tttacccaca
     3721 agatccccat aatgccgttc atttagacgc catgttttta ttataggaag ccataactga
     3781 cccatttctt ctagtgcgac ttgtccggta agaatcgcac gtttcaaaac agaggtataa
     3841 acggcatcga attgaagtcc ggcttcaagc attttttgac cggcaactgc tgcttgttct
     3901 tttccttttt ctgttaaggc gacatctagc catcctgtcc agtaattttc aaaatttgct
     3961 tcgctttcgc catgacgtaa taatactaat ttcattcttt tctcccttaa acattcgttt
     4021 cgaattttat accacatgtt ttgcatgtca cacgtattcg tccttttcct ttaggtgcac
     4081 gctgcttttg atgacaattc gggcactcaa aaaaagtata actttttcga tccattttga
     4141 cttgcttttt gttttttatc tgatgatatt tttctttgac tctatcaaga tatttcaaat
     4201 aacgttgatt ctcatttagt ctggggtaga ttttttttga taggaaacga aatatcatcc
     4261 atccgaaaaa gacgatgaac aacaattgtc cgattctata gggcaaccaa cgacttagca
     4321 aactaaagac aagcgcagcg atcaatagac cgcgattcaa ctgatcaaat ttcgcatatc
     4381 ttccctgcat aagtttgtga tagttctgct gaaatcgtat tagcctttct aaccatgttt
     4441 gcatcatatt atctcctcca tcatctaata tttattatga caaaaaaatc caaaaagaaa
     4501 aagccttaat tggccttttc cattgcaact tggtgaagga cattccgatt tctggtaaag
     4561 tcaatcacaa tcactttctt tttatcttct ctgttgacta ctcgaaatgt gtccgtcaat
     4621 ggaagaaaca gcttcttaga tggtagctgt tgcatacgta taaaacgatg gatcatcgta
     4681 atcaattgag gaaattgaat agacgtgtga agcagacctg gatatttttt caacagctgt
     4741 gtcgttttga tcagattccg ttttttactg atcactttta aaaagctttt tagaatcttt
     4801 tgctgacgtc taaaaataga aaaagaattt tcgtcatcta tttgataacg catttgtttt
     4861 tgcagttctg ctgcagtcag atggatcttc ccatcgtttg tatcgatcat taaaccttct
     4921 ggaaacagtt caaccactgc tcgatcccaa gattcaagag aaagctcgat ataatctttt
     4981 actggtaatt ccaattctac ctttaaaaag tgcaaaacag ccgacagccc ttctgcttga
     5041 tagatttctc ctaatgttag cccctctaga tggaactctg gtgaaaaatg cagcaatgtt
     5101 ttattttcct gcaattgaac atatagaaat gtagatcgct caatcagagt atcttttaaa
     5161 acaactaaaa aattcatttt tctccccctt ttttcatcat ttttaaaata gcatattttg
     5221 aaaagaaagt ctgatgctta gagtagaatt tcataaaaat ttactatttc ataagtattc
     5281 acgagaaaaa tacaaacaaa aaagcggaaa taacgctcat ccgccttctt gtttgtgttt
     5341 atttcctctt caaacgcttg tctatgattc agacttttct ctatcgttat tttcatctaa
     5401 aagttcttgc attccgataa tttctcgata ttgatgaatc ttagtgatac caatgacttt
     5461 gtctacatca atactaaaac aaataccatt acctggaata tcgatgttga tgccttgacc
     5521 aatcgcatcc attactttat tcgtcaaact atcgggtact aatgtcaaca caatatcttt
     5581 ttctggcgaa atgtccaaac ctaaaaattt ccctgaatca tgtacaccag aacctcttcc
     5641 atgtaagatc gttccgcctg ctgcacctgc ttcttttgaa aagtcgataa catcttcgcc
     5701 cattcctccg tcaacgatcg tcacaatcat gtgaagattc aatgctacaa gatctttcat
     5761 ttgctttccc ccaatttttg caatctttct ttttcgattc tgtctttttc atcttttcgt
     5821 ttataaatat atcctagtac taaagtggat aatattggtg tcaatgcaat cattgcaacc
     5881 acaccaaacc cgtcaatgat cggatctctt ccttcaattt gtgcagcgat tgccacgctc
     5941 attgataaaa taaatgtcga acacatcggg cccgttgcta ctccaccgtt atcaaaagcc
     6001 attgctaaaa agatcttgtc cacttttcgt cctaaaataa atgctagccc gtatcctggg
     6061 atcaagaaat aataaagaga gaatccgacg agcaaacgcc acatagacaa tcctactgct
     6121 gcgccgatcc caattgaaat taccatcagc atgattttcg atcggattct cccctcgctc
     6181 aattcttcaa cctgtttgat cattacatga atcgccggct cagcaaaccc tactaagaac
     6241 cccattaaaa agccaagggg aaccagtata taattgtaag gcaatcccgc aatagcactg
     6301 cctaaatgct gtcctaccgg tacataagcc atattgactc cgtgcaggaa aaggatcaac
     6361 ccaatagtcg ttatcaagaa acctttcata atgtcaaaga aacgcttttt gcgcatacga
     6421 aaactaatga tattcattaa aacaaatagg attacgatag gtgccactgc caaaatgact
     6481 tccatggtaa cgatttcgat tccatctatc acttgctgcc agaaactcat tggaagatca
     6541 cccccaaaat catcacggca agaatcggcc ctaacgaagc aataccgacc attccaaaac
     6601 tgtcattttc atttttcttt tgtttgatca tactagtcat ccctccggca agggccaaga
     6661 taaatggaac agttactgga ccagtagtca ctccccccga atcaaaagca atcggcataa
     6721 attcggaact ggtgaaaaat gaggcgatca aaacgcctat gtagcctata gccatcaatt
     6781 gataatagga tagcttgaat acgacccgaa gcagcgcaaa ggctagaaat actccagtgc
     6841 cgacgctgac gatcccaatc agcaacactc tgccaatctc tccgtcagat atatcatata
     6901 cttgttgtcc caaaacttgc acggaaggtt cagcaatcgt gatcacgatc ccgatagcaa
     6961 atcccaaact gaccaaaacg gtcaaacttt tctttttgat catatatttc cctactagat
     7021 ctccgacttc catcatagaa taatctgctc caaacaaaaa gagcgtcatt ccgatcatca
     7081 tgattgccgc accaaccaga aatgaagcga ggtcttctcc ttctaacggt gcaaaaacaa
     7141 acgttaaaat gacaatcagg acagtcatcg gcaatatagc agcaatcact tctttaaaat
     7201 tttttagcat gtatcctcct cctttactct ttaagtttac cttaaaatga aagagttttc
     7261 gagcacaaac ttaaaacgtt atcatttaat ttttctcaac ataaaataac acacgtccca
     7321 aaagtatctt tttacttgga aaaatgactt tgaaggaacg cgcttattgt gtttttttat
     7381 tttacagagc cgatcattcc ttgaacgaat tgcttttgca aaacaaaaaa tacgatggca
     7441 gttggtaaag tagcgatgac taatccagcc atgatcattc catagtctgg tgtataggaa
     7501 gcacccatag cagataaaac aagcggaacc gtccgtttat caggagattg caaagctact
     7561 aagggccata aataattgtt ccagctactc atgaatgtga tgattgcagc cgcggcatag
     7621 gtatttttag ccgtcggcat atacactcta aaaaaaatac ttagttcttt tagaccgtct
     7681 aatcgagcgg cttctactag atcttttgga aaagatttaa cattttgtcg aaagaagaag
     7741 atcaaaaaag cagtgctaac agatggcagg atgacaacca agaaactgtt gattcccaaa
     7801 accgttccgt tcaattgtga aaacattcga tataaaggga tcatcaatgc cgcaaaagga
     7861 accatcatcg atagcagtag aatattgaaa attaggtctt ttcgtttact ttgataaatc
     7921 tcaaatccat atcctgccat tgacgaaatc agcaatgcaa acacagtggt caccaaagcg
     7981 atcatcgctg aattccaaag ggaacgagta aaattcagct cattggaaaa caaattttga
     8041 aaattgatga tcaagttact gccaatcttt atttttcccg atgtgatatc cacgggtgta
     8101 ttcgtcattc ccaaaaccat ccagacaaaa gggaaaatgg aaataaatga taggatgctt
     8161 aatgctgtat actttaatac tgacccaatt gtcgaacgaa gttctaatgc ttgttttttg
     8221 acgttggggc gttcgattgt ttctttttct accatatttt tcatcgactt tctcctccta
     8281 ctttcgtttg gattatcgac aatatcacaa taaaggaaac aataacaaag gaaactgctg
     8341 ccgcatatcc aaaattaggc gtgaatttat aactcaaatt atagatgtat tgagataggg
     8401 tggtcgttgc atttgctggt cccccgccag taatattttg tacttcatca aaaagctgca
     8461 atgtcccgat cgtcgaagta atggaagtaa acaaaatgat tggttttaaa tttgggatcg
     8521 tcactttgat aaactgctgc catttagaag caccgtcaat agatgctgct tcataaatct
     8581 ccgaatcaat attttgcatg cctgaaagga aaaaaatcat attgtatcca gtccaacgcc
     8641 aagtgatcga aagaatgatc agaactctcg cccaaattgg atgagtcaac cagccaatcg
     8701 gtgtgtcaat cataccaatg cccaacaaca agttgtttac aaggccagat tgagaaaata
     8761 gacttttcat gatcagagaa taactgacca tcgaagtgat acatggaaga aagatagcgg
     8821 ttcgaaacaa ccctttatat ttcaactttt tatcatttaa aaggttggaa ataaaaagtg
     8881 ctagaaacaa catgatcggt acttgtacaa gtaaatacag gaatgtatta aaaaaagctt
     8941 ttttaaaagt tgcatctgtc aacatccgct gataattacc taacccgtta aatgtcatat
     9001 tgacaggggg accactttga aaagacgtga tcaaagccaa aaccatcgga ataaaaacca
     9061 tgattgatat caaaatgact ggcaagatta aaaaagcatg cccgtttttg aataaatctt
     9121 tctgcttcat tcttttccct ccaattctat cattgattat ctacatgaaa agacaagaaa
     9181 gacaatatct gtaaggcaga cgtgatcttt tttgtctttt cgtttgtctg atgaaaaagc
     9241 gaagaaattc acttttttac caccgatcaa ttagccaatt gtgcttctac ttgtttttgt
     9301 gtatctgcta gtaccttgtc tgtctcttct ccattgatga ttcgatgaag agcttcagct
     9361 acgactgctt caattgcata ggtctcatgt ccgtaattca cttctggtat ttcagatgtc
     9421 catgttgaaa aatcgtcaaa gatcttttga ccactgtaaa attcagaagc ttcttgataa
     9481 gcttcttgtt cattcgcgct aagcatcgta gatactagtc cgatttcttt cgcaagagtg
     9541 cccatcagtt cttcattcga agcaaacgtt gcttctagga aatctttcgc tgaatcttct
     9601 ccagctactc ctttgatcac ataccagcca gcgccgccaa ggttagaagc ttgcgctttt
     9661 tgcagatttt ctggaagtgc aggtattggt gcaatcttcc attttccaga ttggttttct
     9721 gctccttgga tcgttgaaga ataccaagcg ccagttgggc tagaagctac tgctcctgat
     9781 tgtatcgcag ttactccagc attccagtca gaggtttgtt cgactagatc ttctttcaaa
     9841 agagtggcaa acaattcaag accatacttt aaagatgcat tgtcttggat cgtgactgtc
     9901 tccccatctt cagatgtata ccattctcct gcctgttgca taatcatcct tactcgacca
     9961 aggtcagaag gattgacttc agcgattttc tttcccgtct tttctttgac atctcgcgct
    10021 acttgaatat actcgtccca cttcagattc tccatatcct cttctgtata acctgcttct
    10081 gccatcagat ccgtacgata gaagtttgct gttacgcccg aatcgaaagg aacaccgtat
    10141 attttatctc ctactttgtt taccgcaaat ttatacggtg caaaatgatc ttcctttaca
    10201 atagcagaca aattagcgaa tgcatctgga taagaagtca aatagccttg tatcctataa
    10261 tcttcaatca agacgatatt gggcaatcct tctgtattcc cgctcgctaa agcggtgttc
    10321 agtttctgaa cgatatcatc ctgagacatc gtaacaactt ctatctctgt ttcttcgttc
    10381 tcataaactt tttttgcttc attcactgct ttgatattga atgtctcatc ccacgcccag
    10441 acagtgactt tttcttcttt gtctgctgta ctactagcac ttccgcatcc tgttaagaaa
    10501 cctgatgctg ccgctaaaca aacgactcca gcaattaact ttctgatgtt catttttatc
    10561 cgctcctttt ccatccatta gttgtttacg tttgctacat tcatcatacc aaaatttgaa
    10621 aacggtttct ttattattca gatacttcaa aaatttctcc taaaataata aaaaaataca
    10681 aatcaactat gacaaaagga ataatcttag catctagacc aaagatcgaa atggtgaggt
    10741 ttctttaaaa taaaaatatc cttgcatttt ctcctagaaa taagtatttt taaattacaa
    10801 gactattctt aaggcgggta aaaaaatgcc aatacgcgta attcttatcg atgatgaaca
    10861 gacgatttta gatggaatga aacagttgat caattggtct gagcacgggt ttcaattaat
    10921 agggactttt tccagtccgc tgaaagcgct tgatttttct ttggtacatg caatcgatat
    10981 cgtggtcaca gatgtaatga tgcctgaatt aaatggaatc gaattatcgc ggctattaaa
    11041 acagcaacaa cctgaaacac agatccttat cctctctagc tatgatgaat ttgatatggt
    11101 taaagattct tttaaagaag gcgtcgctga ttatctttta aagcctcgat tgagtcctga
    11161 tttttttcta aattccttaa ctgccgtttc acaaaaaatc aaaaaaaagc ccaacaaaag
    11221 cccaatcacc aatcgttatg agcagatctg cgagaatctt tcacagcaga ttgctggaca
    11281 aactcgtcca ttgcttgacc ctcttctttt tgaacacacc ttgtttttct gttatatacc
    11341 gaaaaacggc cattcagttc aaaacaaggc tctaaacaaa aacagtcgat cacccattca
    11401 ttgatggata gcgacgattc gtttactatt tatcctgttt ctaccttttc ggaagaatcc
    11461 ggctatgtaa tcaatactga ttccaaagat acacttagga agtttgttca aaagtttcgt
    11521 caagaagttt ttccaggtga tttttttgtt gtttctgatt cttttgcaat ccaagatatc
    11581 aatgaaatat tccaagagat cagaaattgc accaaaggac aacgtttcta tcataaggga
    11641 aagaaccttg cttatcagca tgaacttctt ccgttattaa ccaaccacga gcagcaagca
    11701 agtagttatt taacaaaaat cgttcataaa gactacgctt tagctgtcaa agaacttgag
    11761 aatttcttca cgacgatatt ggaacagcct attgatccag cttatttgaa acatgaggca
    11821 atcaatcgtt tctatgcatt actcaacgct ttggctgacg agcatgttgg gaatgaagaa
    11881 ctttctttgc tcaagatcgc ccttccttct ttattagccg atgctgagta tttcgaagat
    11941 ttttctattc ttgtcaaaga aacacttgag aaactcaccc acttttctgc aaatgcaaaa
    12001 aaagacaatt tcgatatctt gactttgatc tacgagttcg tccaggaaaa ttatgagaaa
    12061 gaaatcaatt tacaactttt atccgaaaaa tatcattttt catatagcta tctctcagcc
    12121 atctttactg aaaaatttgg tatcaacttt tcaaaatatc taaaaaaagt ccgtatcagt
    12181 aaagccaagc tctttttgac ggaaacacgg cttactttga cggaaatctg tgagaaagtc
    12241 ggctataccg aactgggtta tttctccaga gtttttaaag aagagacagg aatgacacct
    12301 tctcaatacc gtaaaggaac ttttgtaaaa tgagaaaaaa aatcaaagag catgaactct
    12361 ttgccaaact tctgttcatt ttgttcatcg gtctttttct gcaagccatc gtcatttctt
    12421 tgtttattta tcatcgatca agggatgcct atatccagct gttcaatcaa tcgaatgatg
    12481 tggtactaaa aaagattcaa tctgaatttg aaagtttgaa tgatacaatc gagaatacat
    12541 tagccgcttt tgattctaat ccagctgtca aaagctattt ttccaatgat ccagcccaac
    12601 atatggaaca gcttcagcaa ctaagaacaa tccaaaaaat gaatgactct ctttcaaaaa
    12661 tccatccaat gatcgattac gatgtattga tctttggaga aaatggaaga acttttgtcg
    12721 gaaacgacat gctcactgcc gtatctgccg attctttttt tcaatctgcg attgctcaga
    12781 gagtgaatga acgtgctgct gatacacaaa tgctttttgc acaccacgga ttgactcttc
    12841 gcgataagaa agcacccagc gtcttctttg tcaaaaaact gaaaaataca ttgaatcacg
    12901 tttacggata tgctgtttta tcgatctcat ccaagcaact agcgaatctt tttcaatctg
    12961 tagtaaatcc tgagatatcg aagatctcct tcatgaacga agaacagacg atcatcgcat
    13021 caaatgaaga aaatacaatt gggagccgat caatgatttt caaaaaacta acagtaggtg
    13081 aaacaacgat ttcaaatgga cagcagttga cccgtcttcc tctgtaccgc caggattgta
    13141 cattactcag tcaagtcgat cttcattctt tatctaacca aatgggcgtg atttttccga
    13201 ttattttgta taatatcgtg acacttgctt ttgctggctc attggtattt atgtatttgg
    13261 atcgacacac aaaatcgatc taccgcttga ttgattcgct aaaacggcta gaggaagatg
    13321 gcttaaaagc tactgttcct gtacaaggaa gccatgaagt ccaattgcta gggaatacga
    13381 tcaatcaatt gctaagtaat gctcagcatc attatgaaca gacgatccaa gacgaaaaga
    13441 agaaacgttc gcttgaaatc caaactatgc aagcacagat acagccccat tttatttata
    13501 atacgctgac tagcttgaaa tttttgattt ggcagaaaaa aacagatgaa gcagttcaag
    13561 gaatcgacag tttcattact ttactaagaa gtacgattgg gaaaaaagaa gaagtgattc
    13621 cagtcaagga agaaatcaaa agcgtacaaa gttacatcga tcttttgagt atgcgatatg
    13681 gcgaaagaat ctcggctaaa ataatgattc ctgatgaact gcagtcatta tctatgccga
    13741 atatgatcct tcaaccaatt atcgaaaacg cctatcttca tgcttttcac aataaaacgc
    13801 aaggattcat cacggtgtac ggcaaaacaa aaaatcagct tcttttattc gaagtgattg
    13861 ataacggcga tggcttcgat actgaaaata ccaaacaaaa aaatgatcat ttttcaggaa
    13921 tcggcatcag ccatgtagat gagcggatac gcctaatgta tggcgatgca tatggcttaa
    13981 cgatccaatc agtgattggg acaggaacga ctgtaacgat ttgtctaccg cttcttccta
    14041 aaaatcaatc agaatatcaa aaataaagaa tagccaagcg ctgatttttt tattttaagt
    14101 taaataaatc aatcagtatt cttgactttc atctacgcgt ctcttctact gtcagcactg
    14161 gataacagcc caatatttga ctttctcctc cgagcatctt gatttcttgg agcgcattct
    14221 ctactaatgt cattggacgg tccaacaaca aatcgatcac gaaaaaatat tctcccaagc
    14281 tagttttcaa tggtcgggat tcaatcttac ttaagttgat ttcccgccag ccaaaagctg
    14341 ccagcatttt atgaagcatc cctggccgat tagcaggtag tgtcaagatg acactcattt
    14401 ttactggagc tgactgctgg ctggtcatct ttcggtcacc gacgatccaa aaacgtgtct
    14461 ggttcaactc attatcttgg atattctcag ctaagatctc caatccaaca tgctgtgctg
    14521 tttctaatga agcaatcgct gctgcgtctt ctttcggatg ttctgctaca tacattgctg
    14581 cagcagttgt tgattctgtt gctactaaag gaacattagg ataatgcgtt tctaaaaact
    14641 gttgtgattg tgctagtgct tgtggatgtg aaaggatttt tgtaatcttt gttgctggat
    14701 tgcctaaaag ctgctgcttg ataggaagaa cgatttcact tttaacttcg acttctggat
    14761 gtttggaaag aagatcgatt gtgtgatgaa cagctccttc caatgaattc tctacaggaa
    14821 cgacagccag atcgacttgt ttgcgaaaca aagcgcgcaa acaaacaggg atggaagcat
    14881 acgcagtcaa ttgttctgta ggaaatagct gacaagccgc ctgataagtg aatgaacttt
    14941 ctggccctag atagctgacg ttcatatgct tttgatcctt tctataatgg tatcgatgat
    15001 cttttctggt gtttgattgg tcgtgttgat tcgatgtgtc gcactttctt cataccaaga
    15061 aagtcgttgt gccaataatg cttttatttc ttctcttgtt tttccaagag ctaaaggtcg
    15121 aatagacgtt tcatcttgtt ggatacgatc aactagacag tccgcttctg cctctaagta
    15181 aagaacaatc ggctgtgttt ttaaaaaacg ccgattttct gcactttgga caatccctcc
    15241 accagtcgcg ataattttgt cttcatttga cagctttctt aaaatatctg actccacttt
    15301 tcgaaagctt ttttcaccgt aatagtgaaa atattcggca atcgacaatt ggatatgttc
    15361 ctcaatcttt gtatctaaat ctacatactc tttttgtaaa cattgagcta accctttacc
    15421 gattgttgtt tttccagcgc ccatgaaacc aatcagcaaa atgctagcca tgagcttctc
    15481 ctcctgacac aagttctgct aaatcgtcaa aaaatgccgg ataagagatt gaaacagctt
    15541 cagctccttc tagttcgcaa ggtccatcag ctatcaaagc agctacttgc agcatcatac
    15601 cgattcgatg atcgcctctg ctggacactt ttgcgccatg cagaggtgtc ggcccatgga
    15661 tgatcagacc gtctgctgtc gcttttatct ttgctcccat tttctgtaat tcttctgcca
    15721 ccgcatcaat tctgttggtt tcttttactt ttaattcttc tgcgtctttg atgatcgtga
    15781 ttccttctgc ttgagtagcc actaaagcta gaatgggcaa ttcatcaatc agacgcggaa
    15841 tgatttctcc accaatcgtt gctttcttca aatgactcgt cttgacactt aaatcagccg
    15901 attggttctg ttcattgtga ttcgtctggg taatcgctgc gcccatctcc tccaacacat
    15961 ctaagatacc agttcttgtt ggattgaccc cgacattttt taacaacagt tggctttccg
    16021 gaacaagaag tcctgctgct agaaagaaag cagctgatga aatatcacct ggaacagtta
    16081 tctgttgacc agttaatttt tgcggtccgg tcactatgat cgttttatct tccactgtga
    16141 tccttccgcc aaattgacga atcatttctt ccgtatggtt acgggaacgt tctttttcaa
    16201 cgattacgga tgtgccttct gcttgtaatg ccgcaaacag caaagcagat ttgacttgcg
    16261 cactggctac aggcatattg tatcggatag gtgataaaga gcgggttcct gtcacagtga
    16321 ttggtagata ctggtcattt tcttctcctt gcaagtcagc gcccatctcg cgtaaaggtt
    16381 ccatcactcg ccccattgga cgtttagaca acgaagcatc cccgaacaga gtagtcgtaa
    16441 aaggctgtcc agccaaaata cccatcaata aacgtatggt cgtaccggag tttcccatgt
    16501 caattgattc ggttggttgg acaaatgagt ggctaccgcg accatgaatc ttgatcacct
    16561 cttcctcttc ttcgatctcg acacctaatt gttggaaggc atgtaaagta ctcagacaat
    16621 cttctgcgcg caaaaaattt tgtatagtcg tcgttccttc agcaattgct ccaaacatga
    16681 tgctgcgatg ggaaattgat ttatctgctg gtatcctaac agtccctctt aatccatgta
    16741 tttgttgtaa taattgcatt tatccagcct cctatttgat ccagcaatga taactggtat
    16801 tagacataat gattcttttt gcttgtaaca aatcctgttg gtttttaaaa ctgatttgca
    16861 gtattcctaa aatatcttcc ctggtctctt ggatcttcaa attaatcaaa gaaactcccg
    16921 cttttccgat cagtccagtt acttctgcaa taacgccagg ttcatctggc acatcgataa
    16981 ataaatcaaa aaaggcagga atcgcgcctt gcttatggac aggcaactgg tctcgacttt
    17041 cttttgcccg attgaaaaaa gaaaagattt ccgattggtt ctcagtcatg atccattctg
    17101 ctatttgtgt catttcttgt tgccaatctg ccaatcgttc caataatatc tgcttattgc
    17161 tcaacaaaat atctgtccac atgacaggat ctgaggaagc gatcctagtg atatctcgaa
    17221 agcctcctgc tgccagttgt ttggctcgcg gatactcttg attgaattgt tctgcctgat
    17281 tgactaagcc agctgccaga atatgtggaa aatgacttag cattcctgtt atacggtcat
    17341 gttctcttgc tgtaagagtt acatattttg ctttggttcc gcaaaatagt tcttgcagtt
    17401 tttcaacatc ttttttcgtc ttttccaaag gtgtaaagat gtaataggca ttttcaaata
    17461 gtttagcatc tgctgcctgt atacctgatt tatgagaacc agccattgga tgtccaccga
    17521 caaaccgaag atttttctgc tcagcggatg tcacgacttg ctgcttcgta ctgctgacat
    17581 ccgtaatgat gacgtgatca gacaagttga ttctttcaag gacatcaaga taagctaagg
    17641 ttgtacggac gggaacggct aataagataa cgtctgcttg ttctgcacct gtttcaaaat
    17701 cacttgcaac gtaatcaacg atctgctgtt ctactgcttg ctcacgggtt tttgactgac
    17761 tatcccaacc aactactatc agttctggat tggtctgacg aatacaaagt gccatagaag
    17821 caccaatcag tccaagcccc acgataaaaa catgttgtgc catcttattt gccccctttt
    17881 tagtaatgtt tcaagtagtc acggtactcc ttcactgcag ctttcaactc aacaagcgaa
    17941 tcacttggga attttgacaa tagctctgtc gctaccacag tggctacaac attttccgca
    18001 acgacgctag ctgcaggaac tgctgtacta tccgaacgtt ctacacttgc tttgtaaggt
    18061 tcttttgtat cgatatcaac actttgaagt ggcttgtaca atgtaggaat gggtttcatg
    18121 accccgcgaa tgacaagtgg ttcgccattg gtcattccgc cttcgaagcc gcctagatta
    18181 ttggtacgtc ggaaatagcc tctttcttct tcccatagga tctcatccat cacttctgag
    18241 cctggtaatg aaccagaagt gaatccgacc ccaaattcta cgcctttaaa ggcattgata
    18301 ctaaccacag cttgtgcgat tttggcatct agcttcgtgt cccattgtac gtagcttcct
    18361 aatccagctg gaacgcctcc aacgagcact tctacaattc ctccgatcgt atctccattt
    18421 ttctttgtct gatcgatcaa atcttttatt ctttgctcaa ctgctggatc aacaactcgt
    18481 acttctgacg cttcagaaat ttctttgatt tcttgaatcg agatatttcc aggtatttct
    18541 gcttggattc caccaagaca aatcacgtgt cctgctacga tgatgtcaag ttcttccaga
    18601 attttcttgg caattgcgcc gattgctaca cgcatggtcg tctctcttgc agaggaccgt
    18661 tcaagcacat tccgaagatc tcgatgatgg tatttcatac cgcctaccaa atccgcgtgt
    18721 cctggacgcg gacgtgcaac tcgccgcagt gattggtctt tttcaggcac ttctgctaca
    18781 gacatgacag ttgtccaatt tttccaatct ttattttcta ccactaaagt gacaggtgaa
    18841 ccaattgttt tgccgtgacg gatgccagac gtgatccgaa cacgatcttt ttcgatcttc
    18901 atccttcctc ctctgccgta accagcttgt ctgcgagcga gttcgtgatt gatttcttct
    18961 tctgacagag gtaatcctgc tggtagtcct tcaataatgg ctgttaattc tggtccatgg
    19021 gattctcccg cagtcatata acgcatctta cagtcctcct aagtaatctt tgaatgtctc
    19081 tgtgggaaca ggaacgattt ttgcttgccc aatcttttct agcaagatga tattcaattg
    19141 gcttcctctt gctttcttat catgggttat cgcgtggaat aattcatctg gatgacttag
    19201 atcgtacgta atcggcagat ggaatttttg aagtatcctt tctaaagcag ctgtcgatcc
    19261 agttggagac aagccgattt tttctgcatg agaagtgatg gctaccattc caatagctac
    19321 tccttctcca tgactgacta ccccatatcc tgctgtattt tcaattgcat ggccaattgt
    19381 atgaccaaaa tttaaaataa gtcgatttcc ttggtcaaag acatcttctt ccactacttt
    19441 tcgtttgatt tccaacgtag cagtaatgat tggaacagca tgttccagaa gatctttttc
    19501 gtctttcagc tcgttcagct gtttccaaag cgttgcatct gctatagctg ctgatttgat
    19561 gatttcagcg attccttctc gtaaacgacg taccggcaaa gtttttagaa cctcaggatc
    19621 aatcaataca ccagctggct ggctaaatgt tccgacaagg tttttcgctt tgtttgtatt
    19681 gactgctgtc ttcccgccaa tactagaatc tacttgtgca agtagcgtag tcggaatttg
    19741 aacgaaatgg atcccacgca tgaacgtcga ggccacgaat gctgctagat cacccaccat
    19801 tcctccacca agtgcaagta tcccatcgct gcgggtaaaa tcattatctg ctaaaaaatc
    19861 gtataactca gctgcttgtt ctaaagattt actggtctca cccgccggta cgattgaaag
    19921 gactggttca aaattagctt gtctcaattg gaacatgatt ttttctgcat atagtggagc
    19981 aacgtttgta tcagtgatca cagctacttt ttgaggtctc caaatcgttt gaagccatga
    20041 tccagcctgt tctagtgcgc ctttttcaat atgaatatcg tatttttggt tatcaacatg
    20101 tacagtaagc attcgtttca cttctttctt ttaaaaagct ggaattaatc gagtgtctga
    20161 atcttttcca ttgcttcttt catgatcgca acttctttca tcatgcgtga gtaagtcttt
    20221 tcattcaacg attggggacc gtctgaccaa gcatttgcag gatcaggatg gatctctacg
    20281 atcatgccat ctgctccgct tgccacaccc gcacgagcca ttggtggtac aagttcccaa
    20341 attcctgtac catgacttgg atcaacaatc acagggaaat gagttaattt tttcatcaat
    20401 gggacagcac ttaaatcaaa cgtattacgt gtcgctgttt cgtaagtccg aatcccacgt
    20461 tcgataaaaa tgacaggaga tttgtcttcg actgcaatgt attctgcagc attaagccat
    20521 tcattgatcg taccggaaat tccacgtttc aatccaacag gtttacctgt tttaccgaca
    20581 gcagatagca gtttaaaatt ttgcatatta cgtgcgccaa tctgtaggat atcgctgtac
    20641 tcagccacca tatcgatatg cccttcatcc atcacttcag taatcacttt cattccaaat
    20701 tcatcagccg cttgacggat gtatttcaat ccttcttctt ctaaaccttg gaaagcatat
    20761 ggagaagtac gtggtttgaa ggcaccacct cgcagaattt ttgcgccccc ggctttggcc
    20821 attcgcgcac attctctgat ttggtctaat ccttcgatag aacaaggacc agccatcgtc
    20881 acgaaactgc cgtcaccaat ttttactccg tctacatcca cgactgtatt gccaggatgg
    20941 aattctcgag aagtcaattt gtatgtgttt aaaatacgca cagcattttc tactccttca
    21001 tagcgtgtaa atgctccttc ttgtaaactt cgcgtatcac cttttagtcc aatcactact
    21061 cgttctgttc cttgatcgat tgagactttg aatccttctt tttcgatatg atcgacgact
    21121 ttttttattt gttcttccgt tgcttctttt ttcataatta ctatcattgt ttttcccgct
    21181 ttcttttgtt tacttatcta tcttggctga ttttctctac tttttcaagg tggttttaca
    21241 ttaattccta ctaaatgacc gtgtcctgtt gttctcattt tcgctccttc tttcctactt
    21301 atgacccaga taatcaacaa aaaaagatgt ccctgtagga aattgcctct acagtgaaca
    21361 tcttcaacga gccttaaaaa gcgctgcaaa aatataaaat agccactata gatgaatttc
    21421 tctacgtggc tgtaagtcgt gtttaaaaat ctttagccat catagataca aacctggttt
    21481 gtttgtaccc acgaagtcat gaatacaaac ctatctaaaa tagctaaagt aatacgtatt
    21541 cagttttgta agttttctag atttcataaa aaatcgctcc aaactgatgt aagaattgta
    21601 cctagtatag acataaaaaa atcgactgtc aatcattttt atgaaacttt ttttaatttt
    21661 ctgatagtta actttgtttt tcagaaaaat aacaattggt tttattgaag aaaatagtca
    21721 tgaacaaaag tatctgagaa cttttttact ctcttgttca tgacatatag aataaagcag
    21781 ctttgtcttg taaactccgt ttttcaaata ataatctaaa gattgctact gaataataaa
    21841 gccgatttca tggtcctctt cgctgctgat tcggtaaggt gactcaacat ccgctcccca
    21901 gctattgata cccccgactc ctcttacttt tgcaaaaatc gtaagaaccg ttcgtctttc
    21961 tggcggtagt tcttctatat gtgttgcctg ttccagttct tctgctttga atggtaaagc
    22021 ggaaaaagca aatggcgtat cctgctgttc aaatcgcaac gaaaaatctt cttgatcttt
    22081 atccgtatta tccaacgttt gatttcttgt tagttctacc catttcgttt ccatatgcat
    22141 gccgcattct tggggaacaa ggtatgggga aacggggagt cctgccactt tataaatacc
    22201 ttcgacacca ccagccatcc gatccggata tgtttcccct gataggcctt catactcaaa
    22261 aaattttgct ttcgttggca taatgaacct taaacccaat gcgggtaatt ccggtaatcc
    22321 tttttgtcca taataatgca tattgacaag cattttaccc tctccagcga tttggtagga
    22381 aattgtcact tgggtttttg gtactgtgtt gatttccagt gtaaaaatga tttcaaccgt
    22441 ttcagcgtat tcattacttg aatattgatt atttactgga gcaatcggca aatcgatctt
    22501 tttattgtcc accagtactt ctatttcttt gacttttgga tacaatccgg ctcctaacca
    22561 cataccggat ttaaatccaa atccgctacc tctgtcatta tcggtcgttg ctcgccaaaa
    22621 aactggaagt gtttcccggt atagccattc ttttccgttt ttattgagcg attccagtcc
    22681 gcctcttgta taagaaaaaa tataatgcgt attccccgat ttgacaccta atgtacagtc
    22741 gccgaagacg attgcaactt tttccgtatc catatgactt ttatttactg tatttttcat
    22801 aataatatct tacctcctgc atggcgggtt tttcttgtcc atctgcaaaa acgatcccat
    22861 tccctgagaa ttcatagtca cttggtttat cgtcaaagtc accgccatag cgcatcactt
    22921 ctctgcctgt gattggatca gtcacttgga tcgcctgatc tttaaaatcc catatatagc
    22981 ctccttggta catttcataa cgatcaagca acgtcatgta agaatccatt ccacctaacg
    23041 aattccccat gtcatgcata tattcacata agatgaacgg tttttccgct ttattttcaa
    23101 ggtagtcaat gatctcttct ggtggcgcat acatgcagct ttttacatct gaaatcgaat
    23161 cttcgaatgc tggatttgga aaattccctt cataatggac aagtcgatcg gggtctactt
    23221 ttttgaagta atcgttcatt tgtcgaatgt tttcttccgc ataagattca tttccaagag
    23281 accaaaaaag aatacttgga tggtttttta atgtttcgaa attcgttttt gctcgatcaa
    23341 gaacagccgc ctgccactga ggtactgcac ctggtacgtt gtaagaaggc tcaaatgcgc
    23401 ccattttttg ccatgagcca tgggattcga ggttcgtttc cgccatcaca tggattcctg
    23461 cttggtcgca taaataatac caagtgatct ggttggggta atgagatgtc cgtacgccgt
    23521 tgatctttgc attttttatg atagccaaat ctttttccat atcttctata gtgatggcgc
    23581 gtcctttttt cggatgccac tcatgtcgat ttaccccgtt gataatcatc cgttttccat
    23641 tgaagtagat gattttatct ttgatttcga ttttacgaaa accgaaggaa tagtcaatat
    23701 actccgttac tcttttttct tcgtctatcg tctccaattc aagcttatat aaattgggct
    23761 gaaaatgccc ccacagtgcc acattttcaa atccatcgat gcgaatcgtc atttgctctt
    23821 ttaacggata ttgctgttga tagatttcct tcccatcagg atctagtatc gctacattca
    23881 gctgactgtt tttggctact tgctcaaaag acaaatctac ttcaagtttg ccattttgac
    23941 atttgtcatc taagcgaggt ttgatccaaa gatcttctaa atggttttgt cctcgagcaa
    24001 ctaagaagac atctctgaag atcccaaaaa atcggaaaaa gtcctgatct tccaagaatg
    24061 cagctgtact tcttttgtaa acctccacag ctagaatatt ttcttcttcc aaataaggtg
    24121 ttaaatcaaa ttcagacgga gtgaacgaat cttcggcata cccgataaaa tgaccattca
    24181 accaaataaa cattgcttgt tctacaccag caaaatgaat cgagatttgt tttcccttta
    24241 gaccttcttc taatcgaaaa gtcgtcaaat acgaaccaac cggattgtct ttagcagctg
    24301 aaaagatccc ttccgcctct ttctcagggc ttgtcgtgaa agggggacgg cgaaatacat
    24361 gtccctccca cggatacatc gtattgatgt aatggatctt gtcataattt gctaattcaa
    24421 tatgactagg aacagtgatt tcatcaaaag aacaggcatc aaaatctttt ttataaaatg
    24481 tttttggtcg taccgaagga tttggcgaat aacaaaaacg ccatgatcca tttaaagact
    24541 gtttaaggga ggatgtggtt tctacttctt cccttgttgc ataacaaaca tgatcgctat
    24601 gtgcatttga ttggttcact ctaaaaactt gtggatcatc taaccatttt atatttgctt
    24661 tcatactttt ttccttctct ctcataactt tttgaaatga agcagttctg tttggaaatc
    24721 accttgaaaa tcggggaagt aaagtccaac tgtcatcaat tcggcccccg aaaatatccg
    24781 cttcgaggtc tgttcctgat aaagtgcctc atcatctaac cccatcagat atacttcatg
    24841 gaacgctggt tgagctgaag ctagtatcct ccctaaaaac acaatagctt catcttgttt
    24901 aggagacaca aacatccatg cggcaatatt ttcttcaaaa ggactcgcca aacgataata
    24961 atggccatac tggatcaccg gacgaatcgt ttgataggat ataatttggt cttttacttg
    25021 cttttcttct tcaggagaca gctttgtcaa atccagttca taaccaaaaa cagcgctcat
    25081 agctgtttct cctcttgttt tcaacgaagt agatctgtcg gtctgatgat ttggtacagc
    25141 tgatacatga gctgtgatgg acgaaatcgg ataagcaagg cttgttccat attggatttt
    25201 catacgctcc actgcatccg tgttatcact tgtccatgac tgcggcatat aataaataaa
    25261 cccggcatca aaccgtccac ctccaccaga acagccttcc cataagattt ccggataatc
    25321 agttgtcaaa tgttcaagta gttcataaag cccgagcata taacgatgcg ctacttctcc
    25381 ttgtctctgt gggtcaaggg taatcgaata gacatctgaa agcgaacggt tcatatccca
    25441 tttgatgtag tcaagaggaa tcgtatctaa aatctttctc atttgtttct caatcgtctg
    25501 ccgaacatct aaccttgtaa aatccagtac atgttgtgat ctggaagcag aaggcattct
    25561 acctggctcc tgcataagaa aatcaggatg tgttcgatac agttcagaat caaccgagat
    25621 catttcaggt tcaaaccata aaccaaattt caatcctttg ctatgagcat aatctgctat
    25681 ttcacgtaat ccatttgtca acttgccttc atactcgaac cagtctccta atgaagaatt
    25741 gtccgcatct ctttttccaa accagccatc atctaatacg aacatttcga tgcctagctc
    25801 ctttgcttca tcaatgatcg ccttgatttt ttcactattg aagtcaaagt aagtggcttc
    25861 ccagttattg accagaatcg gccgttcagc aaattgatga cgacctcttg cgattctttc
    25921 acgtagcaac tcatggtgga tctgactcat tttgttcaat ccctgacttg agtaagaaag
    25981 gatcatttca ggtgtttgaa aagactggcc tgcattcaat tcccacgaaa aacgatggct
    26041 gttgatccca ccgacgactc tcaattgatt gatctgatct ttttcaagtt cgaaagaatg
    26101 gttgccggaa taaacaaatt gaagtccgat cgcttctcca gtattttctg tcgtatgatg
    26161 atgaactaaa gcaataaagt tattcatatg gtgactgctc gttcctcgac ggctttcaaa
    26221 tacttttgtt ccagataaaa cagattgccg tgaaatctgt ctttcattga catgtgctcc
    26281 tggcaaagca atgacttcat caaatcgcct agtatgggca aagtctagct ggaaactagc
    26341 cgctttttct agtttgattg tttctccggt ttcatttctt atctttacag atcgtgtgat
    26401 cactgctcta tcagtaaata tggtatagaa caaatcgaaa taaatcgctg tttctctatc
    26461 cttaagtgaa atcaccaacg tttgtgcctc tgacttgtcc atcacataag tttgaggcaa
    26521 gccttcgatc tctggcttcc catctgtaat ataatggctg tcatatctca gatccagtaa
    26581 gtctgatcca ttcttgcgct gaatgatcga tgcgggcgtt cgaaagtcca tgctgccatg
    26641 agaagagtat tcttgcggta gtgtatcttt cgacagagac cggtcaggat ttaagggaac
    26701 atttcctgaa aatccacgat ctcttcgggg ataattttta ttgtctttgt actgcttgac
    26761 tggtttgcca aaataaatat gcgccaatac attgctttct tctatcttta tcagataaga
    26821 aagaaatgta tttcgtaaat ggaagactcg gctcttttca tcaaataaga tgaaattttt
    26881 atctgttttt ctatgcgtaa tatccatcat ttcactccca acaaaacgga aaccgtttac
    26941 ttttttttat aattcctgta tactgtttac taaacaattt tgtcaataaa aattttttat
    27001 ttttttgagg agtgtgtaaa aatggttgga attagagatg tcgcacgaaa ggcaaatgtc
    27061 tctcctgcta cagtttcccg tgtgttgaat aacgatcaga cgatccatgt ggctcagact
    27121 actcggcaac ggatagtaga ggcagctgct gcgttggatt atgacatcag tactcgtaaa
    27181 tatatcaaaa agagaatgcc ttcgattggt gtgatctcta cgatcggcaa agcgagcgaa
    27241 gaacaggata tctattacaa acatttgcga gtagggatgg aagaagaagc tcgacgtctg
    27301 catttaggga tgaatcgaat ctataatcta tctgataatc ctaaacaatg ggaagatcta
    27361 gatcagttag gtgcggtgat cgttgttggg actgttacga aagaatcgat taccgccttg
    27421 ttaaaacaaa acatgcaaat agtcgtcgtg gataaccctg acatccagca agaggtcgat
    27481 atggtgtatg cagatcttga acggatgact aaaaccgtac tggaattgtt cttagaaaat
    27541 ggtcataaaa gaatagccta tatcggggga tataaagtcg atatggatga attcggtggg
    27601 aagcagattt ctataaatga aaagaggatg cgtgcctatc agcattttat gatcgatcat
    27661 cacttagaaa aatatatgtc ttatcatcta ggtggctgga cagaaaaaca aggtgaggta
    27721 cttgcgacta atctattaga aaatgaatcc cctcttccta ctgccattct tgtcgggagc
    27781 gatccaatgg caattggtgt ctatcgggca ttgaaacaaa aaaatatcca aattggagaa
    27841 gagattgttg tagcaagctt tgataatatc gagacaatcg caaacctctc ccctggcttg
    27901 accagtgttc aaatcaatgc gaaatcaatt gggcaagcag ctgttcgaat ggcattggag
    27961 cgaattgacg gtatacggga cgaaccaatc attttgactt atcctgcacg attgattgtt
    28021 agggaaagtt ttatcccaag aacaaaaagg tattgaaaga gaggttgtga aaagccgctt
    28081 cgtttcttca tactcaaaac gaaacggctt tttcacaacc tcttacttat acttattcac
    28141 aaaatccaat gtctgctggt aacaattttg cgattctttt agcgtgtaat caaattggta
    28201 ttcatgggta atctcttttt ttgtatctgt ataaaacaag gattgcacgg gtacctttaa
    28261 ttctgtcaac cgattttcta atgcttgacc ttgctcctgg aatgagtatg catttccgtc
    28321 agttatatac gttggcggaa attccttaga aacatggtca gccacactag cttctttcaa
    28381 ttgctcactc gttttccaat cttttgttcc aatcaacgac cacgcaacgg ttttgacgaa
    28441 aaacttcata aatcgatcat ccgaatgctg ctgtgctgtt agcttcaaat caacaggtcc
    28501 gcaataagaa atggttcctt tcagactatc ttttggaagt agatgtttga ttttcatttg
    28561 tttagcatac gcatcattcg tttgtatagc tgcatattgc aatgcgattt gtgaacctgc
    28621 actatctcca ccaaaaaata attgttccat gtctagcaat ttgtcgtctt tttcttcagc
    28681 taataaatct ttgatcagtt cattcacttg aagaacttga ttagggtatt ctgaatcagg
    28741 cgctaattca taattcatcg caaccactgc gatgttggcg tctgaaacta attttgtcgc
    28801 aaattctttg acacccgatt tatctccgcc gacgaatcct ccaccatgta cccaaaatag
    28861 aacaggaaca ggccccttgc tgttttttgg atagtagatg tcataagtat tctctttata
    28921 cttggactca tacgtcaaat ctgttttttt cgccacgttt ttttctgctt gatcgaacgt
    28981 ttttttatca gtgatttgaa cagtatttga aaacatatgg ttgatcaaga atgctccagg
    29041 tctgggggaa agctggaagg caagaaagat tgcaaacgcg atcccaagaa tgattccgaa
    29101 gaaccatccg ataaatttaa gaattttctt tttcataagg ctccctcagt agttagtatt
    29161 aagcattctg attataccat agtgttattt cctatcaagc tctcctagat gatttaatga
    29221 ttttccccaa acttcttctg caatgctttt gacaaaagaa attttttcca ttgttcttca
    29281 aacaaaacat tttcttcttc tgttgaagca aatccacatt gaggacttaa gcacaaacga
    29341 tccaaaggca gatatcgtgt cgcttcgtag atccggtcaa tcacttgctg gtgctcttcc
    29401 atttcgccat ttttcgttac agtcaaaatc taagacaact aatttatctt cagagacttt
    29461 ctctaaaaga acaaaactcc cagcacgttc actatcgtat tctaaataat aggcacggac
    29521 attttcttga gtaaaataat gggtctgcta cgtcgtcatc ccccctgatg ccgccaaaat
    29581 cgaataataa tttccgcgtc aaacatgtat atttagtgtt gaatcatttg agaatatgaa
    29641 aataaaaatc tttttgatca atcagttaat caaattgaaa taacgaaaaa tctgagacag
    29701 aatgacgttc attctgaccc agatttgatt ttgcacaact caacagtcct tattggcaaa
    29761 tcgccaaaat aatgtagact aactaaaaag actaagaaac aataacaaaa gttaacactt
    29821 cttagtcttt ctttagcacg tctatttatt aaagatttta gggccttttc tcatgttttt
    29881 acgatcattc ttaggtgttt ccatttgttt ggatcggcct ccaccttgtt tctttttgat
    29941 caattctttc attttttctt tttggtccat ttttattctc ctttaacgaa tgaagcgact
    30001 aattcgatat gatgggtttg cgggaaaaga tctacaggct gaactttctt cacggcataa
    30061 cctgcttctg caaataactt agcatctctt gcaaaagttg ccggattaca tgagatatag
    30121 acgattcgtt ctggtgacat ttcgattgct gattcaataa aatgatgatc taatcctttt
    30181 cgtggagggt caactacgat cacagatggt ttgatccctt tttcttgcca ttttttcata
    30241 actttttctg cttttccgac ttcataatga acattttcga ttttattatt taaagcattg
    30301 aactgtgcat cttcaattgc ttctggaata acttccatcc catacacctt atccactctg
    30361 tctgctaaag acaagccaat cgtacctatt cctgaataag cgtcgatcac aatgtctttt
    30421 ttatctaact cggcaaactc gatggctgtt tggtacagat actctgcttg ttgagtattt
    30481 acttgataaa atgactttgc tgagattcga taggtttttc ctaatagctg atcttcgata
    30541 tagtctctgc catataaaac tttttctttg tctcctaaaa tcacatttgt tttttcttca
    30601 ttgatatttt ggatgaccga aaccacttct ggcaattctt catgaatagc ttcagcaatt
    30661 tccttggatt taaagaattt ttctttacga gtaactaaaa cgaccatcat ttcatgggaa
    30721 taatgaccac gacggataat gatgtgacga agctgtcctt catttttttc ttcattatat
    30781 cctcgtactt ggaaccgttg caagatatct ctgactactt tgattgcttg atcgatgaca
    30841 ggatcttgga tataaaaatc ttcgataggg actagatcat ggctattctt tttgtaaaaa
    30901 ccggtggcta actgtccatc gatacggcga acagggatct gtgctttatt acggtagccg
    30961 aatggttctg ccattccgac cgttggaagt acaggaactt ctggcatctt agcaatcttc
    31021 gccattacat gctctacttg tttttgtttg aagacaagct gttgttcata cttcaaatgg
    31081 gctaaaggtg cgatacctat gcgaagtaat gcattgtttt ctacaggctg acgatcaggt
    31141 gattgtgtaa taaatgtttc gacttttcca tatccaaact tattgcctgc ttttactact
    31201 agtatttcta cttcttctcc agggagtgca ttttcgataa ataatggata accatcgatt
    31261 tttgctaccc ccattccttc ataactcaag tcgacgattt cgactgtata tcgttcgttt
    31321 ttctttacta tttgctgttc tgtcatattt tgctccttta agcctatttt tcaatcctac
    31381 tgaactctac tataaatcag ctaattacac aactaaaacc ggcactgacc ttactacgtt
    31441 cagcaccggc ttttgattaa ttcttttgat taggtgtttc gtctgctatt tttccgtcac
    31501 cgtcgatatc ttcatccgtt aaacgttcga cttcttttac gaattctttg ctgacaacct
    31561 ctaattcttc ttcatctgta cctgtgattg cttcatcagg aatctgatcg gtattggcaa
    31621 agaactcaat gtgttgatga agattttgga aatgcatcgg tgcttccccg ccgtattcac
    31681 catctaagtt gatcattact ggtcgattga tatcatcttc tgtttcaacg aacaaactgc
    31741 ttgttttggt atagattatt cttggatcat cgacatgtcg accgccattc agcatgagtg
    31801 ctgcaatatg caagatctca aagatatttg ctgtcttcac aatgattaaa gaaaacttcc
    31861 catcatccaa tttggcatct ggcgcgatct gttcgaatcc tccaacagag ttcgtcagcc
    31921 ctaggaaaaa catcgaagca tttccgatat attccccttc atcatacttc aagcgcattt
    31981 tgattggctt tactcgaggg agcatctctg ctcctttcgc aagataagca agataaccaa
    32041 aaatactctt tagttctgat ggaacttcat aagtcaattc tgtcaaatag ccacctgcag
    32101 cgatattgat gaagtaactg ttatcagaaa ggccgatgtc catttttacg gtttggtgtt
    32161 tttttatcac ttctgctgct gctttaatat tatctctagg aatttttaat gctcgagcat
    32221 agtcgttcgt tgtaccagct gggatgatgg ccattttagg acggtgttca agcggagcga
    32281 ttccattaac cacttcgttg attgtgccat cgccaccagc tgccactact agatcaaaac
    32341 ctagttctgc gactctacat gcttcattct tggctgaatc tggttctggt gtagttgcat
    32401 aggcgctggc ttcaaatcct gcttcttcta atgcctgtag gatatccgcc aaattttttt
    32461 tcaataattc ttttcccgag gtggggttat aaattacgcg tgcttttttc attttcagcc
    32521 tctatcgttt cgctaattca tctttaagta gcttattcac gacaccagga tttgcttgtc
    32581 ctttagttgc tttcatgatt tgaccgacta ggaagccaac cgcacgatct tttccatttt
    32641 tgaaatcatc gacagattgt tggttgttat ccaaaatttc attaatgatt ggcagtagtt
    32701 tgttcggatc agataattgc acccaaccat ttttttcaac tacttcttgg gcttctccgc
    32761 catttgtgat caattcacgg aagacttttt tggcgatttt tgagctgatc gttccatcgg
    32821 cgatcaaacg aatcattcct gctaagttct caggtgtcaa ttttgtctca gctaattcca
    32881 gtttctcact gttcaagtaa gcagaaactt cacccatcaa ccagttagat gcttgcttgg
    32941 catctgcacc attttccaaa acagcttcaa aaaaatcaga catttctttt gtaagtgtca
    33001 ataccattgc gtcatactct ggaagtccaa actcacggat atagcgttcg cgacgagaag
    33061 ctggcatctc aggcaaacta gcttttactt tttgaatcca ttcgtcatcg atcacgaatt
    33121 tcgggatatc aggctctggg aagtaacgat aatcactaga cccttctttg acacgcatca
    33181 aaactgtttt attcgttgtt tcgtcaaaac ggcgtgtttc ttgttggatt tctcctcctg
    33241 aaagaagaac ttttgcttga cgtttttctt caaaagctaa accttttttc acgaaagata
    33301 aagagttcaa gtttttcaat tctgctttcg taccgaactc ttcttgtcca taagggcgaa
    33361 gagaaatatt ggcatcacag cgcatagagc cttcttccat tttcacatcg ctgacttctg
    33421 taaattggat aattgatcgc aatgcttcta gataagcgta tgcttcttct ggtgaacgca
    33481 tatcagcttc agaaacgatt tcgatcaaag gcgtgccttg tcggttcaaa tcaacgtaag
    33541 aataaccgcc aataccatgc atgttttttc cagcatcttc ttctaaatgg acacgttcga
    33601 tccggatttt tttcttttta ccttctactt cgatttcgat ccatccgtca tgaccgattg
    33661 gttgatcaaa ttgggaaatt tgatatgctt ttggattatc tgggtaaaag taatttttcc
    33721 ggtcaaaatg agtatcttta gagatttcac agtttaatgc caaagctgct ttcatcccga
    33781 attccagcgc agctttattc attactggca gcacgcctgg ataaccccag tcgatcacgt
    33841 ttgtattgct gtttggttct gcaccaaaat gagctggcgc tggagagaaa atttttgagt
    33901 tggtttttaa ctcgacgtgg acttctagtc caatgactgt ttcaaaattc attcgtcttt
    33961 ccctcctaaa atagctggtt gttgtttatg gaattctgtt gcttgttcaa acgcatatgc
    34021 cgcttgatac atcgtttttt catcaaaata attaccgatg atctgcaatc caactggtaa
    34081 tccttctgat aaacctgccg gtacagacat acctggaagt ccagccaagt tgacagggat
    34141 cgttaagatg tcactcatgt acattgtgat tggatcgtta atgttctcac cgattccgaa
    34201 tgcaactgtt ggtgaagatg gcccgatgat caagtcataa tctgcaaaga ctttttcaaa
    34261 atctcgtttg atcaatgtac ggacttgtcc tgcttttttg aagtaagcgt cataataacc
    34321 cgcgcttaag gagaatgtac ctaacatgat acggcgtttt acttcttcac cgaatccttc
    34381 tgaacgtgag ttgacatata catcatctaa tgatttcaca ttttcagagc gataaccgta
    34441 gcggatacca tcgaatcgtt gcaaattgga acttgcttct gatgaggcaa tgatataata
    34501 aacagccaca ccgtattttg aatgaggcaa gctgacttct tccacaacag cacctaatga
    34561 acggaatgtt tctgctgctt tcaatacagc ttcttttacg ccaggggcca caccttcgcc
    34621 taagtattct ttaggtaaag caatcttcat tcctttgatg tcgcctgtca gtccctctgc
    34681 aaaatcagga actgaaacgc ctgaagaagt accgtctttt tcgtcataac cgctgatagc
    34741 tgtcaatgct aatgcattat ctttcaccgt acgggtcatt ggtccgattt ggtcaagaga
    34801 tgaagcaaag gcaatcaaac caaaacgtga gacacggcca taagtaggtt tcatccctac
    34861 gatgccgtta aaagctgctg gttggcggat acttccccca gtatcactac ctaaagaaac
    34921 tggaatttgt ccagctgcaa ctgctgctgc agaaccacca gaagagccac caggtacttt
    34981 tgttgggtcc caagcatttt ttgttttctt gaaataagaa gtttctgtac ttccacccat
    35041 agcaaattca tccatgttta gcttaccaac agggatcata tctgcttgat agattttatc
    35101 catgaccgtt gcatcataaa ttggttcaaa attgtaaagg atcttagatg cagcggttgt
    35161 caagatatct tttgttacga tattatcctt gataccaatt ggaataccag caaggacgtt
    35221 gctttcatca atcccttttt catctaaagc ttttgcctgt tccaatgctt tttcttcgtt
    35281 caatgtaatg aatgcctcga cctcaggctc tgtttctttg attcgttcaa atgttgtttt
    35341 tgtcaaatct tgtacagtga tttctttcga tacaagcata tgatgcagtt cttctagaga
    35401 acgattgtgt aattctgtca ttatgcgcca gcctccccat tatcgatgat tgcgggtact
    35461 ttgataaagc cgtcttctgt ttccggcaca tttttcaata attcatcgcg gttccatcca
    35521 gcttgcgccc gatcttgtcg catcacgttt actgtttcaa ccacattcga cgtaaatgga
    35581 acaccttccg tatctacttc ttccagcatt tcaaccatat cgatgatttt acctaattgg
    35641 tcggtaaaac ttgcaagttc ttcatctgcg aacgcaagtt ttgctaattt ggcaacgtgt
    35701 ttcacttgtt cttcactaat cgccatacta ccccttcttt ctaaacgagt taaaaacttt
    35761 gctctctatt ttaacacaag agtgccgtgt ctgaaattgt ttattgaaat ttgtctgaaa
    35821 aaactcattt ttcattcttc tactgagcga cttttagcca atgcatctgc catttgatct
    35881 tctgtccaaa cttcgattcc taattcttgt gctttggtca gcttgctgcc agcatcttct
    35941 cctgctacca cgatatccgt ttttttcgat acgctaccag tcactttccc gccaagattt
    36001 tcgatcgtct cttttgcttc ttcacgagta aatcgtgtta gtttaccagt aaggactact
    36061 gttttttctt taaaaggaga ctcgacttct tgcaattggg catttcgaag ccctttgtat
    36121 tcgaaattga cgcctgcttg ttttaattca ttcatcaatt catggacttc ttcgttactg
    36181 aaataagtga ctacactgtc ggcaatgata tcaccgatcg tatcaagcgc aataatcgac
    36241 tcatagtcac ttttactcaa tgtttctaga tcaccgaaat gttctgctaa aatttttgct
    36301 gctttcgctc cgacatgtcg gattcctaac ccgaaaatca accgctcgac cgaattatct
    36361 ttgctgttgt cgattgctgt caaaatatta tttgctgatt tttcttttat tttgtccaac
    36421 gtcaataact cttcttctgt caatttgtaa agatcagcaa catctgctac tagtttttta
    36481 tcatacatct gttctagtac gcgcggcccc aacccatcga tattcatcgc atttcttgaa
    36541 acaaagtggt tcaaaccttc tttcatttga gcagggcatt taggattgat gcaccgtaag
    36601 gctacttctt catccaaatg gacaagttca cttccacaaa ctggacaatg tgtaggcaat
    36661 tggtattctt cgctgtcttt aggtcgttta tctaacacga cttgcgaaac ttctgggatg
    36721 atgtctcccg ctttataaat cagaactgta tctttcaagc ggatatcctt caacttaata
    36781 taatcaccgt tatgcaggct ggcacggctt actgtcgttc ctgctactcg gactggtgtc
    36841 atgatagctg ttggcgttac tacccctgtt cgaccgactg tccattcgat gttttcgatt
    36901 agcgtttcaa cttcttctgg cggaaacttg taagctgctg cccatctcgg tgctttgata
    36961 gtaaaaccaa gttgatcttg tagcgagaat tcattcactt tgatgacgat tccatcgatt
    37021 tcatagggca aatccacacg tttgtcatga tattcttcaa tgtatgacca cacttcatca
    37081 atcgaatgac atagacgttt ttcccgattc gtgtggaatc caattttttc tagctcttct
    37141 agcgcatcat actgggtttt tgcttgcata ggaccgaaat cagctactgt gtataaaaaa
    37201 gtgtccagat ttcttttcgc tgtgatttta gaatctaact gacgcaaaga accagctgcg
    37261 gcgttccgag gattcgcaaa gatatctttt ccctctgctt ctctgtcttg gttcaattgg
    37321 acaaatgacc gttttggcat gaaacattcg cctcttactt cgatgttcat tggttctttt
    37381 aatttgattg ggaccgaccg gacagttttt aggttttcag tgatgttttc tcctacagtt
    37441 ccatccccgc gagtcgcacc tctcacgaaa tttccatctt cataacgcaa agaaacggaa
    37501 agtccatcta tttttagttc acagcaatag tcaactacac gtcccactgc tttttgtaca
    37561 cgttgatcaa aagctatcag ctcttctttg ctgaaaacgt cgttcaaact gtaaagcgga
    37621 atatcatgag tgactttttc aaaaccttct aatacttttc cgcctactcg ttgagtggga
    37681 gaatcagacg tgatcaaatc aggatattgt tcctcgattg ctactaattc tgcgtattct
    37741 ttatcataaa catagtcttc cactgttggt ttatcttcta cgtagtattc gcgagaccat
    37801 tggttcagtc ttgtacgaag ttcttctgct cgtttagcag cttcgtcaat cgtcatttca
    37861 tgttccatca tttaccctcc actactaagc tttttcaatt ggcgcaaagg cagccaaaag
    37921 acgttttact ccttgacttg ggaaagccac atctagttct agatccttcg acgtcccgct
    37981 tactcggacg actgttccta gaccccattt tttgtgtttg actttatctc caggtttcca
    38041 gctgttattt tcccctccag tagcactttt agagggaaca accgctgtct ctggctgttt
    38101 atagctatat gctgtttttt tagcgaatac aggcgttttt ttaggcgtag gacgcatgcc
    38161 ttcgatttcc agtaactcct gatcgatttc ttctacaaaa cgagaaggtc ggttatattg
    38221 cgtccgtcca tataatgttc tggagaaagc atttgttaaa tacaacgctt cttctgctcg
    38281 cgtgatcccc acatatgcga gacggcgttc ttcctccagt tcgctttctt ccatcaatgc
    38341 tcgagataaa ggaaaaaccc cctcttctag accaatcagg aatacaactg gaaattctaa
    38401 tcctttggct gcatgcaaag tcatcaatgt cacttgggaa gcatcttctt ctaaattgtc
    38461 aatgtcggaa acaagtgcca gatcatttaa gaagaccgtt agtttttctt ctggtgcatc
    38521 agcgtcttct tcattttgct gttcgaattg tttgtcgaat tcttgtgtga ccgttaaaaa
    38581 ttcctccaag ttttcgatgc gtgcttgtgc ttctaatgta ttttggattt ttaagtcttc
    38641 tagatatccg ctacgatcca aaacctcttt cgtcaattct gtcactgtca agtatgggat
    38701 catctgagtg acttcttgga tcatctctcc aaatgcacct aattgctgtc ctgcttttcc
    38761 accgatattt gccagatcca cattttgcgc tgcttcaagc agtggccatt catgaagaga
    38821 agcaaaactg cgtagttttt cgatagatcc tggtccgatg cctcgtttgg gcgaattaac
    38881 gatacgctca aaactgattg aatcttgagg atttaccagc acattcaaat acgctaaaat
    38941 atctttgatt tctttacgat cgtagaactt gtgccctcca accattttat aaggaatatt
    39001 tgctttcaac agagtttctt ccattacacg agattgtgcg ttcgtccggt acaagatggc
    39061 aaagtcgccg taattccgat gattgcttcg aatctcttct tgcatccggt ctacgataaa
    39121 acgggtttcg tctcgttcat tatctgcacg gtagtaagtg atcttgtttc cttctttgtt
    39181 ttctgtccac aagttttttg gttttcgatt gctattgttt tcaatgactt ggtttgctgc
    39241 gctaaggatg tttttcgtgg agcgatagtt ttgttctagc aaaattactg cagcatctgg
    39301 ataatctttt tcaaaatcca agatgttctg catatctgca ccgcgccagc cgtaaatact
    39361 ttgatctgca tctcccacga cgcacaggtt cctaaatcta cctgccaata aattgactag
    39421 cgtatactgt gcgtgatttg tatcttggta ctcatctaca tgaatataat ggaatttgtt
    39481 ttgataatac gtgagtgaat caggatgttc ttcaaataat cgaatcgtat tcatgatcag
    39541 gtcgtcaaag tccatacatt gattatattg aagctctttt tggtaagcag cataacattt
    39601 tgccgcaatc tcttcgtaat aactgccttg catttttgca aaatcctgag gggtctgcag
    39661 gctgtttttt gcttgagaga ttgttcctaa tatacttcga ggatcatatt ttttcggatc
    39721 aatgttcagt tcttttagta tccgtttcat caaggtcagc tgttcagaag aatcgatgat
    39781 tgtaaagttc cggttatacc cgataaaatc aacatctctt cttaaaatac gcacacacat
    39841 cgagtgaaaa gtcgataccc agacatcttc gcctccagat gcgagaatcg cattgacacg
    39901 ttctttcatt tcttttgcag ccttattggt aaaagtaatc gctaggatgt tccaaggatt
    39961 gacttctttt tcctcaatca aataggcaat gcggtgtgtc agcactctcg tctttccact
    40021 tcctgcacct gccattagca gtaatggtcc gtcagtgtga agaacagctt ctttctgacg
    40081 ggggttcatc ccgtttaata attcagcttt ggatgacatt aacaacatcc tttcttttat
    40141 caatcttgtt aattatagca ttttcttggc tttcattaaa ctagctagtt caaaatcatt
    40201 tgtttctttt tatggatttt tccttgtcaa ttcgttgatt tcgcgctaaa ttaaaagaaa
    40261 gcgaggcgtt tgaatggaaa aaaaaggaaa aatcaagaaa ttagataaga ctcagatata
    40321 ttttattcta aaaggaatat ttgttggact gctgacagga atcgtcgtta gcctgtttcg
    40381 attatctatc gaaaagctaa gcgatttagt tcgaagtatc tatgaaatga gtcgggaaca
    40441 gccgatttac ttaattggcc tagctatttg ctgcatcctt gcagcatttt tcgtgggtta
    40501 tctggtcaaa aatgaaccgg atatcaaggg aagcgggatt ccacaagtag tgggacagct
    40561 tcgcggggaa ttatcaatga actggttctc tgttttatgg aaaaagttca ttggcggtgt
    40621 actttcagtt ggtgcgggcc tttttctagg tagagaagga ccttctatac agcttggcgc
    40681 atccattgga caaggagctg gacaattgtt tcggagtcca tcttcagaag aaaagatttt
    40741 aatttctagc ggtgcaagta gcggacttgc agcagcattc aatgctccta tcgcaggatt
    40801 actctttgtt ttagaagaaa tccatcactc cttttctcca cttgtttggc tgacatcatt
    40861 tgcttcagca atcactgcta acttcgtctc tctttacttt ttcggcttga gacctgtttt
    40921 atatctaggt gaccttcctt ctttgccgtt gaaatattat ggttccttag tgatcttagg
    40981 agtacttcta ggcatcttag gttttattta tcagaatgtc ttgctggctt tgccaaaatt
    41041 ttacaaccga ttgcctttac cagcttattt tcacgggttc gttcctttct tgctgatttt
    41101 gccaattggt tatttatggc ctagtactct aggcggaggc aatcaaatcg ttttagcttt
    41161 tggacatgct tccttgccaa tcattatgat tatcggtttg tttgttcttc gattcgtttt
    41221 ttccatgatt tcttacggtg ggggtcttcc aggggggatt ttccttccga tattgacatt
    41281 gggggcttta atcggtagct tttatggaaa cattatggtt gatttcggga tggatccaat
    41341 ctacatcaag gattttgtcg ttattgccat ggctggttat ttcacagcga ttggaaaagc
    41401 accgctgaca gcaattattt tagtgacaga aatggttggc tctcttaatc atctgatgcc
    41461 tttaggattg gctgctcttg ttgcttatat cgtcaatgac cttctcggcg gtaatccaat
    41521 ttacgaatca ttattggaac gtctacttgg aaatactcag accgcctcac taaaaggtgc
    41581 aaggacaact tttgattttc cagtaacggc agagagttct ttagacggat taatggtacg
    41641 agacttcaat tggcctaaaa atatgctgct aatctctata cgcagaggaa atcaggaaat
    41701 cttgactcac ggtgatacga tcatgaatgt aggagatatt ttggttatct tgactgatga
    41761 agcaaacttg ccaagaatca agcaggaaat cgaggctaaa tcttctatca caaatttgaa
    41821 gcaatcattt taacgaacat ggaaaaacta ttttacaaca actattcatc tacactactt
    41881 gattctatat gattctataa aaaaagaaga ggctgggaaa acccagcctc ttctttttta
    41941 tttctatgct tctgctactg caggagcttt tctcaataaa ccataaatca caccagatac
    42001 gactgctccg atagcaataa acaccaaata catgaccggg tgactcagta agaatacaac
    42061 gaaaatcccg ccgtgaggag ccagtaattt gattccgaaa gctccgacta atccgccagt
    42121 taaagcagaa ccaataataa aacttggaat ggcacgaatc gggtcagctg ctgcaaatgg
    42181 aatcgatcct tccgtgacaa acgatagtcc catcacgatg ttcgtcaaac cagcatcttg
    42241 atctgttttg ctgaatttat tcttaaacaa acgtgtagca acgaaaattg ccaatggagg
    42301 taccattcct ccagccataa cagaagccat cacgacactt ccgccagttg caacagtcgt
    42361 agctaaagtt gctgtaccaa acacataagc ggctttgttg attggaccgc ctaaatctgc
    42421 cgccatcatt ccagctaata atgcaccaag taaagcagca ttcgaaccac tcatacttgt
    42481 caagaaaccg ttcaatgcat cattgattgc tttcataggg acattgacca gcaacatcaa
    42541 gaaaccagta atcagtaagc caaacactgg ataaaagagg atcgttttaa ttccatccaa
    42601 tgattttggt aagttcttga ataatttacg taaaaatacg atgacataac cagctaagaa
    42661 tccaccaatc agtgcaccta agaatcctgc accgcctgta ttagctaatg caccagcagc
    42721 aaatccaacg atcaaaccag ggcggtcacc gatacttgaa gcaataaatc ctgctaatac
    42781 cggcagcatg aaaccaaatg cagcttgtcc gatttggttg aaccagctag cagcttgatt
    42841 gtaattccct agatttgata attgatcatg tggcacgcca ataaattggt cgatcatgaa
    42901 agaaagcgca atagcgattc ctccaccaat aacgaaaggt aacatgtgtg atacgccgtt
    42961 catcaaatct ttgtaaattc tttgtccgat agtaccatcc gcatttcctt cttctgaact
    43021 gctttctttt ccatcaccat ggaatactgg tgcagtacca ctaagggcta gattgatcaa
    43081 ctcttctggt ttacggatac catcactgac aggacgattg atcagttctt ttccgtcaaa
    43141 gcgattcatc tctacttttt tgtctgctgc aacgattaca ccttctgcac gggcgatgtc
    43201 ttcagcagtc aatcggtttt tgattccttc tgaaccgttc gtttcgactt tgatctccac
    43261 acccatttct ttcgcttttt tcttcaaagc atcttctgcc atgtaagtgt gagcgatccc
    43321 tgttggacaa gctgtaacgg caacaacgaa ttttctttct ggatgagcag aagcttctgc
    43381 agcttgtgtt tcttgttctg ctttttcttc tgcttctttt tgctcttcag ctgtttggaa
    43441 caagtcttgg acttcttctg gtgtatttgc ttcttttaat tttcctacga aatctgcatc
    43501 aatcagcaat cgagatagtg ctgctaatgc ttgcaaatgt gtgtcgtttg cgccttctgg
    43561 agctgcgatc atgaaaaaca gataagttgg ctgtccgtct aaggcttcat aatctactcc
    43621 tttttggctt tttgcgaata aaactgttgc ttctttaact gcactgtttt tcgcgtgagg
    43681 catggcgatt ccatcaccaa gacctgtaga agtttgtgct tcgcgggcta gaattccttc
    43741 tttatatgtt tcgatatcgg aaatccggcc ggcatcaaac attttttgga ccatttcatc
    43801 gattgcgcct tttttatcag tcgcttgcaa atccatgatc atcgcttctt tgaccattaa
    43861 atccttgata ttcatgatta tcctccttga aactaatcaa tttttgtgat ttcaacttct
    43921 ggcagcaact catcaatcaa ttcgcgagct gccaagtcat cagaaaaagc tgttgcgctt
    43981 ccgcaagcaa ctccccattt aaaggcttcg attggatctt tcgtacggct gtaagcccca
    44041 ataaagccag caatcattga atcccctgca cctactgaat ttttcaatgg gcgaactaat
    44101 acattcgttt tataagttcc ttgttccgtg aagagcaaag caccgtctcc agccattgag
    44161 atcagcacat tctgtgcccc ttcagctagt aattttttcc catacggaat gatttcttct
    44221 acagattgga aggttgtgtt gtaaagctca gctaattcgt gattgtttgg tttgatcaac
    44281 aacggtttct taacaagtgc attttttagg tcatcacctg ttgtatcaat cacgaaatct
    44341 gcaccttttt ctcgaatgat atcaatcagt tcttgataaa atccttttcg caggctagct
    44401 ggcgcgcttc ctgacaatac gacgatatct ccttgtccta ctgttcctaa tgcttgcttc
    44461 aactcatcga tttcttcatc tgaaatagat gggcctaagc cattgatctc agtttcagtt
    44521 tctgatttta gtttgatatt gattcttgta tcttctttta cggttgtgaa caaagactgg
    44581 atttgttctt tttcaagcca cttcgaaata aattcgccag tgaaccctcc taaaaaccct
    44641 agtgctgtag attgagaatc gatccgtttc aaaatacggg aaacattgat cccttttcct
    44701 ccaggtaact tgaagtcttc cttcattcgg ttcaaatcgc ctagttttaa cccatctacg
    44761 cgtacgatat aatcaattga tggattaagt gttactgtgt aaatcattgt attgcctcct
    44821 taattgttgt cttttcacgg aattcattaa cgaattctaa tggacaacgc tcggttatga
    44881 tcgtggctgc ttccaaaggt gcaacagagg tgaaggacaa ctggttgaat ttggtatgat
    44941 caatcaatac aaatgtctct tcggaatttt tcatggctaa acgtttaaca gctgcctctt
    45001 ctggatccgg agtcgtgaat ccttgttcaa gatgggcacc gttcattccc ataaatgctt
    45061 tattaaaatg aaaatttttt agttgttcta tcgcattaga tcctaaaaca gcattagttg
    45121 ccagctttat cgttccacct aaaataatgg tagcaagctc caaatcaact aaatttgccg
    45181 catgttgaac ggaatttgtc actactgtga tctgttttcc ttgcagaaaa ggaatcattt
    45241 ctaacgtagt agagccagcg tctaaataaa tgacatcttc gtcattaatg gtttcagctg
    45301 ccgatttggc gatttgctgt ttttcgtgaa cgtttttgag tgatttttca ctcatattct
    45361 gctcaaaatt caataattgc tctttcttag ctccgccatg aactctttct agaaacccac
    45421 tattctccag ctcttgtaaa tcacgtctta tcgttgattc agaagcattc aaaaggttta
    45481 caagatcttg tgatttcacg attttctgct gttcaagcaa gtctaggatt ttttgtctgc
    45541 gttcctctgt aagcattttc acgatcacct caatacaaat aatagcatat tttttttcta
    45601 ctagcaatat aaatcagtca aaaacgttca taaaaattat aaatcagtca aaaaaaaata
    45661 aaaaaccagt cagaaagact ggttttttat ttttttgtct atcatcaagc cgttttatcg
    45721 ttttttattt tcgcttcttg tttttttcat ataaacagaa gcaggttttc tttccttatg
    45781 aagaagataa taataaagtc ccatcccgcc aaacatgacc aaaaaaccga tgactgatcg
    45841 aataggaaaa ttaggaacaa aaaagagaca gacggataat aatgatgccg gaaccattat
    45901 tcgataatag agttgtttat ccattttctt cacctcatat tttttgtaaa gtaatcaatt
    45961 gttctaattc tcggtaatct aaaaattgca cacgcagatg ctgctcacct ttcttgacat
    46021 cgaattggat acttcgccgc tttttcttta ttcgtttgaa ggtaacatca gagagtctat
    46081 gtttgatttc ctttaacggt aattctgaca gggattctga aggaacatag attcttaagg
    46141 ataaaagata ctcttgatat ttttcatctg ttacctctac ttctagatat tccctaatat
    46201 aataacaata agcttcgatt ccattatcca aagcaacagt cggatcgata actttatagc
    46261 acatcatgcg tgatcgattc tcgtcaaccc aaggaaaata cgcctgagca tttagtgttc
    46321 cgcgaacacg cctttcttta taatctcctt gttggatatc ataacttttt gttacaaaaa
    46381 atgaagcatt ctttttagga acaggttgca tttgtgcatt ctgatactgg acagattgga
    46441 tcgtatggtc agtgtaaatg tattcaacga atggcggttt caataaaccg acaccattgt
    46501 cccaagcaag atgatcaaac ccaagctggt ccctaaaata ggattgaaac atttgattgt
    46561 ttggcttttg ccagttaaag gggtctcgat aaagctggat acatatgact tcgttttcta
    46621 attccttcac tttttctact tgttggatgt cgagaaaaat cggtttaggg atgatttgat
    46681 gataatagcg actataatac atttcccaac acgaagtgaa acataaacct tggtaaaaaa
    46741 gatcgtatcc tggaaattgg ttgcaatcga ctactacttc cccgttttgt tgtttcattt
    46801 taggtaaatg ttcgatttca tcctttttct caaacaatag ccgttgagag atctgttttg
    46861 tattgtgata gataaactcg ctataagctc gcatataggc gaacacccca tgagcaatca
    46921 tttttttctg aatgaagtct cgaatcaaaa attgcttttc tttgaaaaca gagatagaca
    46981 atacattttt tatcaataat tgattatctt ccaagcgaaa actacattcg ttctcgtcat
    47041 ttcctacaac taaccaactt tcgtctctta ccgatgctag cattattttt tcttgaagct
    47101 ttcgaagatc atacggatcc gcttgttgtg tgaaagagcg gataaatgtt ggctggatca
    47161 acagacgtgt caaaatagcc caatcgctta tttcctgttt tttttcttct tcatttaagt
    47221 ctgtgagctg gatagtcatc aataatttat cttcgccaat cattttctca cctctttcaa
    47281 atctttttat aatttaatta taaccaatga taaagaaaaa ctaaaacttt atgtcttaga
    47341 aaccaatttg gacgattaca tgatagacta agtaaaaaga aacaaagagg tgtttacaat
    47401 ggggttgaaa tttgaacgta cagataattt agataaactt ttcgaatcat ttgctgtcga
    47461 tccggaaaaa acagttgcac caaaagaaga gatcgatcga tttctaaaac cacagccaca
    47521 aaatgaaaag aaaaaagaca agaaacaaaa gtaagttaag ctcaaaaaaa gacttaccag
    47581 ccaaactttt atgaaagagt ttgactggta agtctttttt attcttttta tgattcaatt
    47641 gcttgttcga ttgctgccca cgcttcttct tttccctgtt ttgtaacgga agaaaagaga
    47701 ataaacgtgt cattgcgatc aaaatccaac gcttttttga tttcgctctc atgcttgttc
    47761 catttaccac gagggatctt atctgcctta gtggcaacaa caattacagg gatatcataa
    47821 tacttcaaaa attgatacat ctggatatct tcttgagaag gcttatgacg caaatctact
    47881 aaagaaacga ccgcacgtag ctggtctcta gtcgttaaat atgtctcgat catctttccc
    47941 cattttgctc gctcagtttt ggatactttt gcatacccat atcccggaac atcgacaaaa
    48001 tgtaatgcgt tctcgatcaa ataaaaattc aatgtctggg tctttcctgg cttaccggaa
    48061 gtacgggcta aattctttcg atcaatcaat gtgttgataa aagaagattt ccctacattt
    48121 gatcgtcctg ccagagctat ttctggcaat tgtgtatctg gatattgttt tggtgccact
    48181 gcacttatga taatttcagc ttgatggact ttcatggtct ctctccttaa caaggtgatg
    48241 aataaagcaa gcggctgtcg caaaagccaa aatgactttt acggcagcct cttttcatca
    48301 acccgctttt ttctctgaat ctttatagat tactgttggc tcaccagaca attcagctgc
    48361 ttcttttgtg ataatcactt tttcgatgtt ttcatttgaa gggatatcaa acatcacatc
    48421 catcatgatt tcttcaatga tggaacgaag tcctcgagca ccggtattgc gttcgattgc
    48481 ttttttcgca atggctctca acgcttcagg ttcgaattca agttcggtat tatctagaga
    48541 aagaagtttt tgatattgtt tgactagcgc atttttcggc tcagtcaaga tccgtaccag
    48601 atcatctgtt gtcaatttct ctaaagctgc cataacaggt aatcgtccga taaactcagg
    48661 gatcaatccg aattttagta aatcttcagg aatgatatgc tgcatgacac tttcgtcttc
    48721 agaaagtttt tggttttgtg taccaaatcc aatcgtcttt tcgcccatac gattcttcac
    48781 aatcgtttcg atgccatcaa atgcaccacc tacgatgaac aatatgttcg tcgtatcaat
    48841 ctgaataaat tcttgatgtg gatgtttacg tccgccctga ggtggcacac ttgcaacagt
    48901 tccttctaga attttcagca aggcttgttg gacaccttcg ccggaaacgt cacgagtaat
    48961 agatacattt tcgcttttac gcgcaatttt atcgatctca tcaatataga tgatcccttt
    49021 ttctgcaagt tccacattgt aatcagcaga ttgaagcaat ttaagcaaaa tgttttctac
    49081 atcttccccc acataaccag cttctgtcaa acttgtcgca tctgcgattg caaaaggtac
    49141 attcaatgtt tttgctaatg tttgtgctaa aaatgtttta ccagaccctg taggtccgat
    49201 caagcagata ttgctttttt gcagttcaac atcatctgtg ttttcttgtg cttgctgatt
    49261 gacacgttta tagtgattgt atacggcaac agctaacgag cgttttgcgc gatcttgtcc
    49321 aatcacgtag ttattcaata cttcaagaat ttctagtggt ttagggactt cagtgaattc
    49381 gcgtacagct tcttcataaa attcttcatc aatgatttct ttacataggt cgatacattc
    49441 attacagatg tagacccctg gaccagctac gatctttttc acttcttctt gggttttccc
    49501 gcaaaaagaa cagcgtacgg tctcattgct acttggattg tcatacatgg tcttcacccc
    49561 ttaacttgca aaaagtatgc aagaaactat caaagacttt acagtctttt actatcataa
    49621 catagtttag taaaaagaaa aagtgtttaa caaaggatca actgacctat acctttgcat
    49681 tttttactct taacaaaaaa taaggaactg tgacaaaatc gtgtcacagt cccttatttc
    49741 gaataaacaa ttttctagaa gtagcttctt cagaaatgat ttattacttg atttctattc
    49801 tttcgcttct gtcgctgtac ctgtgatcaa ttcgattgct tttttcattg tcacatcatg
    49861 ttccagcata tcttctgtca acacgcgttt gatttgttcg attggcatgt tgtatgtttc
    49921 tgataattct tggatttctg cattgatttc ttcttctgtt gcttgaagat tttcagcagc
    49981 tgcaattgct tcgatcacaa gatttgttct tgtgcgcatt tctgcttcac cttcgaattg
    50041 tttatgcaag tcttcttctg tagaaccagt taattgatag tacatttcag gagagatacc
    50101 ttgacgttgc atgttgttca agaattcgtc cattgaacga tgtacttcat catgaaccat
    50161 cacgtgtggc aattcaacga tttctgcgtt ttcaacagcc atacggatcg ctgcttcatc
    50221 ttttgcatcg tccgctgctt tttcttttgt ttctactaat tctttgcgat atttttcttt
    50281 caattcgtct aatgttgata cttcgtcatc aacatctttt gcgaattcgt catctaattc
    50341 aggcacttct tttgctttta cttcatggat tgtcactttg aagactgctt cttttccagc
    50401 aagatcttct gcttgataat cttctgggaa agttacattt acatctagac tttcacctga
    50461 tttatgacca actaattgat cttcaaaacc tggaatgaat gagcctgaac ctaattcaag
    50521 tgagtaattt tcgccttttc cgccatcaaa cgcttcgcca tctacaaagc cttcgaagtc
    50581 gattactact gtatcgccat tttcagctgc agcatcttct ttgataacta attcagcttg
    50641 tgcttcttgt tcacgtttga tacgtgcatc cacgtcagca tctgttactt cacggtcttg
    50701 tttttcaaca actagatctt tatattgtcc taattttact tctggtttca ctgttacttc
    50761 agcagtgatt acccagtctt gacctttttc catgctttca acatcgattt ttggttgaga
    50821 aacaggatcg atgccagctt ctttgacagc agcttcataa gcttctggta atacagcatt
    50881 caatgcatct tcatataaag cttcttcacc gtacatacgg ttgaatactt gacgagaaac
    50941 tttcccttta cggaatccag gtacgttcaa gctttttttc actttattaa acgcagttgt
    51001 taatcctttt tggatttcgt cttgcgcaat cgtaaatttt aaaacaccat cattcgtgcc
    51061 ttttttttca aatgttgcag tcatttaatt ccctccgagt ttagaaattc attttataca
    51121 tcaaaaacgt ttcatgcata cctttaaata gtacactaac cctttcaaat tgtaaacata
    51181 ttgaatggat agaatccttg tttttcataa catttttatc tttttcactg ataaaatcta
    51241 atggaagaag atcatttgct gcaaaatttt ttctcttttt tttaaaaaat cttgtttttc
    51301 atcttctgta ccttcataca tcgtttttcc tgtacacgcc tctacagtca gttgaaacca
    51361 gcgcttcggg tcttcgatgt atgtatcata gacaggataa acaattgcag attgcaacgt
    51421 gaattcttct tttaacacgg aactaagcag cgcatcttca ttcccgtaac gatctgaaaa
    51481 tacacataat tgctggtaac ttgcctgctg ctgcggcttt ggcagatctt ttggtatgac
    51541 tttgactaac ttttcttcaa tcgtcaaata gaaaacagga tggcattcgt tcaattgcct
    51601 aagtgtctcc agtaattttg cccttgctaa aatatggacc tctggcgata caataagttt
    51661 actcgctgtt tggataaact catgataagg aagctgttcg atctcatcaa tagacgcaag
    51721 ctgacgtgca ggttccaacg aaggaagttc ctccgattta ttgtggagtg ccttgatctt
    51781 ctgcctctcc atttgtccgg ataattcttc tgcaaattgg attttttcaa tgacccgctg
    51841 ctcgaaagct tcataaaaat ctgtacttgc tatcaatttt ctagcatata aaaaatcttg
    51901 tgtactgatt aacaagtcaa aataaaattc agcaaactcc tcattttgaa gatactgttt
    51961 ttcatgcaag agtgcttgct tcaatgcttc ttttttctcg tccaactcgt aaagacaaaa
    52021 aacaagcagg ctattagcct caaagctttc tttcaactcg taagctcgtt gaaataattc
    52081 ttttgcctgc tgatattgct ggtttgctag tgcttgttgt gccactcgca ttaaattctc
    52141 atatttttct ggaaaatcaa tcggcttcac gcagtgtcct cctcttgctc atattcagct
    52201 catgttcaat agtagcaaaa caaaaaaagc atgacaatta aaaataactg aagcaccctc
    52261 taaaagctag attttagatc tgacttttag aaggtgcttt caactgttac tgctttttat
    52321 tgctcatcag ctgttgactt cctggttgaa cgctttgatc agattgatcg taacaacact
    52381 tgtattagtg aaaaaatcgc ccagatgttg ctttttctga ttaaagactg ctggaagata
    52441 ccctaacatc agcaaaggaa attttagaat gaaccggcaa gcaccttctc taactaaaac
    52501 ggttgaccag ctaagttctt cttcatcaaa gctgatgact cgaataccaa agatcatttt
    52561 cccaatcgtt tggccatgat tgaatttcgt caataaaata aaatacgcta gataaataag
    52621 taaggctgtg aatccgtaga gactcagata agaatctgaa aaattaagcc aacctagatt
    52681 tttggcaata ccaagtgtta aacgcgtaat agctccgata cacaaaagat cgaccaagaa
    52741 ggcaaacatt cggataaaaa aacctgcata gaaatactta ggaaaatcat ttgcttttgg
    52801 cggttcattt cttgtgtccg tatacttttt ccatttacgt tgtttctttt tgatttcttc
    52861 gggcgtcaaa ggctctcttt caaaagagct cagtaccttt tgggaaaagt tggagtcagg
    52921 tcctacagca ggctgctgtt gcttatcttt ttcttgttcc ttattttcat ttgaaagctc
    52981 tgacatgctt actcacctcc gtaataatac attgcttttg gtgattccgc tgtccctaga
    53041 ttctcaagaa cggataagat ctgactagtc tcagaaggct tcaatccctg gaattctgct
    53101 agtttacttc ctaaccatgt actagcaaac ccagatggcg tggaagaata ttctactagt
    53161 tccgcatctt caagctgttg ttcctttcgt atagctttta aagcatcttc aggaaatccc
    53221 aattcatcga ctaaacctac ttcttttgct tggacaccat cataaatcct tccatcagca
    53281 atttttttga cttcttcttc agatttattc cgtccctcgc tgacgattgc tacaaaacga
    53341 ctatatgcgc tgtcgatata tgcttgaagc accgcttctt cttcttttgt ctctggtcgc
    53401 gttcctgaac ccatatcttt caacgctccg cttttaactg ttgtatcttc cacacccagt
    53461 ttttctagaa gtcctgaata attcaatcct gacatgatca caccaattga gccggtcact
    53521 gtttcttctg ttgcaaagat tttatctgct tgagcagaaa tatagtagcc accgctagct
    53581 gccatgtttt tcatgctgac atacattggg atatcatgtt ctttacgaat cgtatccaat
    53641 ttcttagcga tttccgcact ttcgtagaca ccgccaccag gagaatttac ttctaaaaag
    53701 atacctttga ctgttggatc ttcttcaatc gccttcagtt gttccataaa atttttatga
    53761 ttgtaacctt cagaagcaaa taaacctgaa gaccctcccg cagcaatcgt tccatctact
    53821 gataatttta cgattttttg cgtactgtct ccctcttcca acacatttgg agctagttct
    53881 tcatccccat ataaccaact gttcaatccc tcaatttgat cgttttcctg aggcttagtc
    53941 aaactagctg aaactaacga aaccacaaat aatcctgcag caatcagaac tgctgcccaa
    54001 cgtcttttat tcattctttc tcctttctaa tacaagtttt ttatgacgat cacagtttct
    54061 gactgctcag aagtgtcgaa ccgctctgct ttttcttccc gcgcataccc ggaaaacgac
    54121 tcttttgtta attcatcttc taccgtaaac tcacgagctt gagcaacttc caaggcatca
    54181 ggtgcgattt cttggatgct atcccagcca gtatctaaaa atattttcgt atcatctgat
    54241 acaccagctg atgcttcgaa tttggacaat tgttttttta acattcccag tgtcatgatc
    54301 tcaatttttg aatccatttt tactcctcct ctatccgatt actttctatt gtaccgaact
    54361 cctgaaaaag atgatagata aaaacccatt attttttgac ataaaaagga catttgacaa
    54421 agaatttgat atataccaat ttatttttta ttcttttttt gttgacaaga acattcgcaa
    54481 aaggttatga ttttaaatgt ttccagataa aaaacaaaaa ggaggatagt tatacctttt
    54541 aggatagcgc caggtctgtg taaacagatg acgaggagag ggtttatcga aagattcggc
    54601 ggatggccct agggactgca ctctacagaa aatccacaaa aaatgtctgc aaagataaaa
    54661 caaaaggatt ttcctgcagc tggaagcatt catacgaatt cattatagaa agtaggatgt
    54721 tttttatgtg cggaattgtt ggaatgattg gattaaaaaa tgtaacacca ggattgattg
    54781 acggtctaga aaaattagaa taccgtggtt atgattcagc tggtatcttt gtctcagatg
    54841 gcacaactga ttatctggtc aaagcacaag gcagaattca aaatttgaaa aacaaaataa
    54901 atattgatac tacaggaaat ataggtattg gtcatacacg atgggcaact cacgggcaac
    54961 cttctgaaga aaacgcccat ccacatactt cccaaagtgg acgcttcgtg ctcgttcaca
    55021 acggcgtaat cgaaaacttt gaagaactta aaattgctta tttagcaaat gaccacttta
    55081 ttggtgagac cgatactgag attatcgctc atctaattga aactttcgcg aaggatacta
    55141 caacgcaaga ggcgttttta aaagctttgc gggtcatcaa aggttcttac gctttcgctt
    55201 tgattgatcg gacagcacct gatgttattt acgtcgctaa aaataaaagt ccactattaa
    55261 tcggactcgg cgatggattc aatgtgattg ccagcgatgc aatggctatg cttgctcata
    55321 cgaaggaatt cgttgagatt gaagatgaag agatggttac cgtcacatca gaaaaagtta
    55381 ttattcaaaa ttttgcaggt gacatcgtag aacgttcttc attcgaagca caagtagatg
    55441 cttcagatat cgagaaaggt acctatcctt tttatatgct gaaagaaatc gacgaacagc
    55501 ctattatcat gcgtcgtatc gctcaaaaat acgtaacaga agacaatcgt gtctctcttg
    55561 atcaaaagct ggtcgataca ttgtctgata gcgatcgaat ctatatcgtt gcttgcggaa
    55621 ctagttacca tgcggggtta gcaggtaaac agactttgga aaaattgaca cagattcctg
    55681 ttgaggttca tttagccagt gaatttggct ataacacacc tcttctttca aaaaaaccat
    55741 tctttatttt cttgagtcaa agtggcgaaa cagcagacag ccgccaagtg ctggtaaaaa
    55801 tcaaccgtct cggctaccct tcacttacga ttacaaatgt tgctggttct actctttcgc
    55861 gggaagcatc ctttacactg ctattgcatg ctggacccga aatcgcagta gcatcaacga
    55921 aagcttatac tgcacaaata gctgtactaa ctttattagc caaagctatc ggtgataaaa
    55981 aagaatttga aacttctctt gtattcgata tcactcatga attgagttta gttgctaatg
    56041 cgatggaatc ggtcatcgcc caaaaagatt atttagaaga gttggcagaa gtatatctca
    56101 gcgatacaag aaatgccttt tacattggac gtggtgctga ctacaacgtt tctcttgaag
    56161 ctgctttgaa attgaaagaa atcagttata tccaggcaga aggttttgcc gctggcgaat
    56221 tgaaacatgg aacgattgct ttgatcgaag aaggaacacc agtgatcgga atcatcagtg
    56281 aagaagtgac tggtgcgcat actcgaggaa acctgaaaga agtcgaaagc cgtggcgcta
    56341 aaacactagt tattgtctca gagggattag aaaaggaaag tgaccagctg gtgctaccaa
    56401 ctgtccaccc ttatctaact actctaacca cagtcgtacc gactcaatta cttgcatatt
    56461 acgcaacgct attacgggga ttcgacgttg acaaaccacg taatttagcg aaatcagtga
    56521 cagtagaata ataaaagaac aaggaccagt gtcagacatc tgacactggt ccttgttctt
    56581 ttatttttta tgaaaatatc tcttaatcca gtccgatttc ttctttgact actgccgcga
    56641 ttttatcgac atagtaatta actttctcat cagtaggcgc ttctgccatc actcgaagta
    56701 atggttctgt accggaagga cgaactagga ttcttccttc tgatcccatt tcagcttctg
    56761 cctcttcaat cacttttttg attgccggaa catccatcgc accgttttta tcacttacgc
    56821 ggatattcac taatttttgc ggatagattg ttacctctgc tgcaagctct gataatttct
    56881 tacctgtctg tttcatgata ttcagtaact gaattcctga aagcatccca tctccagttg
    56941 tgttaaaatc taagaaaatc atgtgcccag actgctcgcc gccaaagtta taatcgtttt
    57001 tgcgcatttc ttctacaacg taacgatcac caacttgtgt aacgacatct ttcaaaccga
    57061 ttccttccac cgctttgtgg aatcctaagt tactcatgac agtcgtaacg atcgtatctt
    57121 ttttcaatcg atttttttct gccaagtatt tagcacagat aaacatgatt ttatcaccgt
    57181 cgacaatgtt tccaagttca tccaccgcaa taatacgatc gccatcgcca tcgaaagcta
    57241 gtccagcatc tgctcctttt tcaacgacca tctcagctaa acgttctgga tgggtagagc
    57301 ctacgccgtc attgatattt aacccgtctg gatttgtgcc cattgtataa aaatctgttt
    57361 caagatcggc aaacaaacga ttaacacttg ttgaagttgc tccgtttgct gcatcgacac
    57421 aaatggtcaa accggaaagg tcaccgttga tcgtttgtac aaggaattga gaatatttca
    57481 ataagccttc tggaaattct tctacagttc ccaatccttc agctgatgga cgaggcaatt
    57541 catccacttc agcatctaat aatgcttcaa tttctagctc ttggtcatct actagtttaa
    57601 aaccatctgc accgaaaaat ttgattccat tatcttgtgc tggattatga gaagcagaaa
    57661 tcatgacccc tgcgcttgct ttttgcaaac gtgtcagata agcaacacct ggtgtagaga
    57721 tcacacctag ctggaacact tcgataccca ccgataaaag tcctgaaatc agcgcttctt
    57781 ctaacatttg acctgagatt cttgtatccc gccctactaa cacgcgtggg cgttttcctt
    57841 cttcttcatg ctggcttagg acataacctc cgcaccgtcc cagcttaaat gcaagttctg
    57901 gcgtaagttc cttgttggct tcaccgcgta cgccgtctgt tccaaaatat ttacccatag
    57961 ttgtaaaatt actcctttaa cttaattttc tgaggaattt gttctgctca tttgtgttga
    58021 ttcgcttgtt tctgatgttt cttctgtact tgtggtcgag ctgcttgtcc cagattccga
    58081 actggaagaa atggttgttg tcgatggttc cgttcctgaa tcagcagatg aaatacttct
    58141 actcgtactt gtattttctt gtgtccgact gctcgtcgaa gcagagctac tgcttgacgt
    58201 ttgcaacacg ggtgtaatct ccacactaac tgattcgggc ttgatactta acccctcttc
    58261 tactggtatt tcaattttac gagttgttcg atgattgata cctgagacat tgatcggtac
    58321 agcaatactg tcaccgatcg atgcaagcaa atcgctagag ccgcttactt ctgcttccag
    58381 ttttgaaaaa ctgaaatcat agctttctac cccggcagct ggtgttcctt gctgtatccc
    58441 ataaagtcgt accgacttgc ttggcttgat cgaatcagct ctcactgtta cttgcactgg
    58501 atcagagacg atacttaata cttcccctgc tgcattcagc gcctgtattg ggacctcact
    58561 attaatccca tcatctgtga ccatcgaagc gtccacatca gctactactc gtttgatttc
    58621 tgccaatgtt ttgtcacctg tagtgataga gactttttta ggactaacgg aagtatcatc
    58681 aagttcatat ccagatggtg tgaacgttga aggaatcaac gtttccacat cgaaatcttt
    58741 tattaccttt ttctcaaccg ttactgtaat agtcgatggt tcgatctttg ctgtgacagc
    58801 actgctcaaa ttttgaattt ttagcggaac ttcatgtgtt ccttcgccca gcttagtgat
    58861 atctgctgtg acgcggaaca tccgtgtatc ttcgtttgcc tctgcattca actgaactcg
    58921 gtttgcactg gaaagtttga cagtcactgc attttcatat ccatggatat agtagcgctt
    58981 tgaatcataa gaaatcttga tcggcacccc cgtaactgtt tgattatacg cttcatttcc
    59041 agaaagcgta tttggaacgg actggccatt tgcattgaag tacagcgcaa tactgaacag
    59101 caatgcaata aaactgtaaa gaatgcttgt ccgtttctct tttgagatca tttgcgatcc
    59161 cctcccttag tcataccgtc taggaaagat tgaatcacgt ttttcttgtt ttttgttttc
    59221 tcttcagcaa ttagttctct acgcaagatt gccaaatatt cttgctggga taagccagcc
    59281 atcagttcat tatctaacgt gatgctgacg tccccggttt cttcagagac aacgatggta
    59341 atcgcgtcac tgacttcgct tataccgaca gctgcccggt gtcgagtccc gaattcttta
    59401 gggatcaaca tactttctga tagaggaaga taggcgcttg ctactgcgat ctttccttct
    59461 tttacaataa ctgcaccgtc atgcagcggt gtattaggaa taaagatatt gatcagcagc
    59521 tccccagtga tatctgcatc taaagcaatc cctgtctcaa tatactcatc taatccagta
    59581 tgacgttcga tagtgatcaa cgcaccgatt tttcgcttgg acatatattg gatggctttg
    59641 tcaaaagaca agatcatctt ctcatcttcc tgctgttcgc tttttgattg tttgaaaagc
    59701 gaactgcgtc caagatgttc cagtcctctc cggatttccg gctgaaaaat cacgatagca
    59761 gctatcaccc cgtacgtaat gacttggttc atcagccaag acaaggtgtg cagaccaatg
    59821 atttccgcta cgattcggat aacaataaaa atagctacac ctttcagaag ctgaatcgct
    59881 tttgtgcctc gcagcagttg gatcagtttg tatacaagat accagacaac cagaatatca
    59941 agtatgttca ccaaaaaatt cagagagaac aagtcaccgg aaaacatttg ctgccaatag
    60001 tccaaattaa aaagttcccc gatttgaaat gacataaaaa gcctctcttc tcttttgaga
    60061 tttcctctct agtatatcat atgttttaat tttagaggct gatatgctcg tatttttctt
    60121 gagaaaaacg cataattttc aagaaaattg caagtatgcg ttttattttt ctctgcaata
    60181 aatattttta aacttcagag aattattcat tatatttttt ctgttatttt tccttttttt
    60241 cttttgtagc ttgttccatt tttttacgtc gttctgctct ggcagctctt ctagcagctc
    60301 ttctttcttc tgcttcaagg tccgtcgttt tttcttttct agtcttaacg ggtacatcga
    60361 tagattcctc tggttcaagt cgtttcttga ttttttctaa ttctcccgtc agtgcagcat
    60421 agttgtaaaa acgtgtttta gcgtcgtgga cagtcttttc aaataaagct tttgcaagat
    60481 ttggatttgc gttatctagc gaggaaaagc gaacttgttt cctcatgaaa tcaggcatag
    60541 cagagaaatc aggttttttg tagtccaaag tcattgggtt cttgtttttt tcgaccattg
    60601 tagggttata tcgatataat gaccaataac cagaagaaac agcttctttt gcttctttaa
    60661 gcgattcttt cattccgcca agcaagccat gtgtgataca aggcgtatag gcaataatca
    60721 gagaaggacc aggatacttt tctgcttctt caaatgcctt gatcgtttgc atttgattgg
    60781 cacctgaagc aatttgcgcc acataaacat ttccatatgt catcgccatc attcctagat
    60841 ctttctttga agcatacttt ccactagccg aaaatttagc gattgccgaa gctggtgttg
    60901 cttttgaggt ttgaccgcca gtattggaat agacttcgtt atccaaaaca aggatattca
    60961 cgtctgctcc gctggcaagt acatgatcga tcccgccaaa accaatgtcg taagcccatc
    61021 cgtctccacc aatcatccat tggctgtttt ttacgaatag atcctttctc ttgtatatat
    61081 cctccagttc agggaaaatt gatcgttcgc tttcgatcgc agcttgcagt tttgctgctc
    61141 tttgctgcgt tccttcactc tcaaacatgt gtactaacca gtcttccatc aattctcgta
    61201 gttcttctga tacttttggc aatacttctt tgattgaact tgccaaagcc tcgcgacgag
    61261 tctgtgccgc tagaagcata ccataaccaa attcagcatt atcttccaat aaagaatttg
    61321 accatgcagg cccttgacca cattcattgg tcgtataagg agaagcagga gaagcaccgc
    61381 cccaaataga agaacagcct gtcgcattcg cgatcatcat tcgatcaccg aacatttgtg
    61441 tcaataattt tacataaggt gtttcgccac agcctgagca agcgcccgag aattcaagaa
    61501 gcggttgatt gaattgtgta gacaagacag tattctttcc tttgactgga tttgcttttt
    61561 gtcttaatgt cattgcaaaa gcccaattca cagcttgttc tttctgttct tcataaggct
    61621 tcatcactaa agctttttct tttgcgggac aagcctctac acacagacca caacctgtac
    61681 agtcttccac tgaaacttgg atacggtatt ttacgccgtc tgcgcctcgc atttctctca
    61741 cgataaatcc ttctggcgct tcttccattt cctcttcatc tgctaaaaat ggacggatgg
    61801 cagcatgagg acaaacaaag gcacattcat tacacatcgt acagcgatca ctaatccact
    61861 caggtacttc taaagcgacg ccccgctttt ccatagaagc cgttcctaaa ggcatttcgc
    61921 cagttgtcat tccatttgct acaagtgtac caacagagag ttgatttcct tcctgtgcat
    61981 tcactggttc aagtatttct tgtatataac cagtgttcct tttattgatt ttttcaggca
    62041 tctccaacgt tctccaatgg tctgggatcg cgacttgatg aagcagttcg gtcgtccgat
    62101 cgattgcttg tatgtttttt tctacgatag ccattgattt atgtccatag cttttcaggg
    62161 cttcttcttt tagcagcgga agcacctcat caaaaggaat gatgtcagct aatttaaaaa
    62221 aagccgtttc cattgccgta ttgatccggc gtcccaaacc gacttcttgg gccaatctca
    62281 tggcattgat cgtatagaat ctaatgttat tttcagccaa gtaacgtttt aattttaagg
    62341 gcagatgcgt ttctaattgt tcgtcgctcc aaagagtatt caataaaaaa atgccacctg
    62401 gcttcaatcc tttgaccaag tcatagctat gcaggtaagc tggtgtgtga caggcaacaa
    62461 ggtccgcatg ctcgacaaga tacgctgaac gtatcggcgt atctccaaaa cgaagatgag
    62521 agacagtcag accgccagat tttttcgaat cataataaaa atagccttgc gcatatttat
    62581 cggtgtgatc tccaataatc ttgatagctg atttatttgc tccaactgtt ccgtcagatc
    62641 caaatcccca aaacttggcc tggaatgttt gcggttctgt caaatccaga ctttcctttg
    62701 gttccaaaga ttgataagtc acatcatcca cgatccctat ggtaaaccgt tttttgcgta
    62761 tgcttgggtc ttttttcaat tcatcaaaaa ctgctgagat ttggtcggga gtcacatctt
    62821 tagaccccaa tccgtagcga ccaccaataa cagccgggcg aagttcagaa tcatataacg
    62881 cactttgaac gtctaataag agaggttctc cacctgcccc tggttcttta cttcgatcaa
    62941 gaacagcaat tgtttttact gtatgaggca acttttgcac gaatgtttcc actggaaaag
    63001 gacgataaag atggatattc aaaaaacctg ttttccgtcc gtttgcattc aagtaatcaa
    63061 tcgtttgttc aatcgtctgt gcaactgatc ccatagaaac aatgacttct tccgcatcgt
    63121 ctgctccgta ataagtcacc aagtcataag aagttcctcg taatcggttg atctctttca
    63181 tatatttttg aacgatttca ggtaatttat cataataggg gttgatcgtt tcccgttgtt
    63241 gaaaatggat gtctggattc tggttcgtac cactaacagt cggatgattg ggattcatcc
    63301 ctcgtttacg aaatgaagct aatttctcct gattgatcag aggagctaat tcttcatatt
    63361 ccaaaacttc gattttttga atctcgtgac tcgtacggaa tccatcaaag aaattcaaaa
    63421 aagggacttc tccttcaata gaagcaagat gggcaacagg tgctaaatcc atcacttctt
    63481 gtacactgct ttcagctaac atagcaaatc ctgtttgtct tgcagccatc acgtctccgt
    63541 gatctccgaa aatattcaac gcatttgtcg tcactgcccg actagcaacg tggaaaacac
    63601 ttggcagtag ttccccagca atcttgtaca tattcggtat catcaaaagc agcccttgtg
    63661 aagcggtata tgtagttgtc agtgcaccag ttttcaatga tccatggacc acaccagctg
    63721 ctcctgcttc ggattgcatt tctactactt ttactggttg accgaatacg ttttcttttc
    63781 ctgctgctga ccattgatct actaattcag ccatggtcga actgggtgtt attggatata
    63841 ttgcagcaat ctcggtaaat gcataagaaa tatatgcggc tgccgtattg ccatccattg
    63901 ttttcatttt tcgcatgatt catcatcctt gttcatattc tctcttatta tctgttccat
    63961 tataacgtaa aacatgccat ttttttcttt tatttataaa aatattttac atgtatctat
    64021 ttgaattggt catctaattt ttagacaaac agtctaaatc gttgcctttt tttgtcagac
    64081 atgtataaac tataagcgaa agaggtgttt taacatggat atatcagtga ttgatgcaac
    64141 gaaaacaaat acacaaaaag gaatccttta tggttcatcg aatgctccta aaaaaatggt
    64201 cgaattcatc aacttagctt gtccgtattg ccgacaatgg tttgaagaat cttatgagct
    64261 attagaagaa gcagtccaaa gcgggcaatt gcagcgagtg atcaaattgt tcgataaaga
    64321 aaaagaaagc ttacagcgag ggaacgtgat gcaccggtat ctcacaatca gcgatggcca
    64381 aaaagcgatc aaagagatca aacaaatatt cgatactcaa gacgagtgga aacatctttc
    64441 tctccaagaa gtagcggatt ttgcagtaga taaactaaag ctgacagaac aaaaagacga
    64501 acagctgagc caagctgtca tcaacgaagc tgagcaagca catattcgat ttgttccaac
    64561 tgtcatcttg ggtaaagaaa tctttgatga atctatttca atagaggaat taaaagaatt
    64621 gatccaaaca aaataaaaaa ataaggagcg tgggacaaaa gtaaagaaca cttttgtctc
    64681 acgctctaaa cacgtataaa cggcggaagc agaagcaact ccttcttatt tcttggagtt
    64741 aaacgcttct gtcccagcct ccttattccg aataaatggt gtccaaaagc ttgcatctgc
    64801 cagattatct catttcttat gacaagctaa gcaaattatc tccaccaaat aatttattca
    64861 tatttttgac ttgcgcatac taactaattc ttaaattttc atacaaaatt tctcaatttc
    64921 ccttaacgag taatatttat gtacggtgat tctcactagt atcccaatca ctttttaagt
    64981 tatcccgatt tcaattctac ttcaaaaata gttgctttta tgtatgctgt tagttgatta
    65041 gatggtcatt tgttgagcta ggtcgtttat tttaaacaag ttgtttcttt agcttatacc
    65101 tatctcgtct accaaacgca agatggcaaa cacaaatgca tacgcatctg tatttgccac
    65161 tttgattcgt ataaagctaa caactattaa ctcctctcag ctaatagttg ctctcttttt
    65221 tattcagatt catttttgct gatcacagcc tagtatttca atggttttga acactaaacc
    65281 aaattgttcc attacaacat tcactggctg atgaaatgga ttagtagatt tcgattattc
    65341 aaagcgattt tctattggtg gatcgtgttc ccaactaata agacggattc caaacctatc
    65401 gtacagatct tctaaaccac ttataaattt tgcacctatt tcaggtgttt tattgcgtgg
    65461 atattctatt gttacgccat taaatggata ccaattagga ttaggctctc tttttttctg
    65521 tacatctccc atagaatagt tagcactttc tgggacataa tatattcttc gaccatcctc
    65581 taattcatct aataagatat ttcgtgatcg tctatcactt gctaaatgta gacgccacgt
    65641 gcgataccat gccatgctac ctgcatctgc agaaaatcca tcaaataatg caacaattgt
    65701 atcttctatc acaatccttt ccccatctac ttcatattct aatctaaaat caaactcccc
    65761 tcgggtaatt tctggtcttg gtggcttagg acccaatatt attctactta aaaccgcatt
    65821 cgttcccaga tgaaacacag ctataacaac aataatgatt aatattttgt ttctatttga
    65881 taaatttctc attattcgca catcacctct acattctcac atattagttc gtaatactcc
    65941 tttaatatca aaatatctac tggtcgtaat aatattcgct atgaattcct actactcgta
    66001 taagaaaggc caaatcatca gcttttactt gctgatgatt tggcttgttt ctatttatcg
    66061 taattgtttt ctaatcacca aaattgttaa caatcggttc agatatttcc cagttgatta
    66121 aggtaattcc gtattgtgtc aaaacttctt gcgcttctcc gaaattaagt acagttctta
    66181 tgtatccact ttctcctaat ataaagtcta cctctctttt aaaaccttcc tcgagatttc
    66241 taagggctat atgtggtttt aatgacattg attgtacatt ttcccccata taatattgcg
    66301 cacttcctcg actaaaatag attcctagat cgtccccaaa aggtagatct tctctaccac
    66361 tagctaatct acttctccat cttcgttctc ttttcataga acctgcgctg aactcacacc
    66421 cgttaaactc agctatgaca gtatcttcaa ttatgttaat ctgtccatct agttcgtatt
    66481 caatcctaaa tggaaattct ccataggtga tttccggttc gggtatttta ggtgagatta
    66541 atgcaaagaa aggaaatatt aagcttggca acatcaaaaa aactcctcct atgatcacaa
    66601 ttcccgatgt aatccaaaat ataatttgta caattctcat tgatccattg tattccattt
    66661 tattccccct attactattc atatccgcct atctatatcg atcttccaat gcagagataa
    66721 ttgcttccat accttgattt tttactgagt tacctatgcg agatatcatt ctccactaag
    66781 gtgcatcata ttgtctatct aacatgatta attctccaat aggtgtatac tcctccaaaa
    66841 acaacattta atgcatctcc ctcgacaaca taagctacca tgtttgctgt atatgtgttt
    66901 gagtctaatt cataagcaga taaatttact gtcgctggat taaatataat cgcattcgta
    66961 tttatagcta ctgaatttgc tgcttcagca ccaccttttg aatgtccgat cattgtgatt
    67021 tcaatagtag gatttacgtg gacagccctc accgtttacc ctgaccatta tagaaatcgc
    67081 ttactttttt gaactacgca acaaaggata caatgctcct aacttcactg tctccatttt
    67141 tgtccactaa ggaatataaa aaataggcat taattcattt aattcggtca caacacgtta
    67201 ccttttaaat cattatactg tatctcatac attattatca ataaactatt ataaaaatgc
    67261 aaaaaatgct ttatcaatct attttgtaat tggtcataat atcattgaaa tcataccctg
    67321 tatcgatttt tcctatgaat ctcgtctatt tgtgattgac gaaaaagagg caagacagac
    67381 actggaatgg taattttacc cactattttg ctccaactat ttgtaatcgt acccactttt
    67441 gaaataccga gatgatcatt ttaattgata tgctgattcc caagcaaaac cccaagaaat
    67501 taaatgctct atcgcatcta gcttcttggg ttttgcttat ataaattcca acatttaaat
    67561 tttttatgct gttcggtctc agaaatgccg tttttgctta tatcacaata tcaagatgtc
    67621 aaattattcg tgttgccgat gactttgatt attttttttc aaattgttta ttaagactaa
    67681 tgctgtcttt ttgcagatac caatgttcga actttttaac attatcatat gatcctgcaa
    67741 gttttaactt cttaccatta gatgttatca aagttataat taaccttgcc tttttcccat
    67801 taggatcttt tattttatga attttctgca ggtaatctct cctaatggca gctattttta
    67861 cctcatcagt gctgataaac cattgatcat ccacatacat actgcctgtt atgttgtgtt
    67921 tttccatttc ttccgagaac gaaaagttta aggctcgttc ttacttccaa agttgaatga
    67981 gtccatggat tggacttagt gtgagaattg agaacaacaa taagaatcca tatcctcccg
    68041 caaacatccc taaggctata ctgtctctcc atccataagt aggattagaa gagaaaagag
    68101 tcaccgtttg taataatatg aaaaggaata atccagcaca aacaccaaag ataacaactc
    68161 caaacattga atttttatac aatgaccatt tatttatagg cttttctttc attttacttc
    68221 cccctactgt tctgttcaca cggaatgaat tcaaagttca taagccctcc tctttgaaca
    68281 tatgaatacg acttgctaac tatactttaa aaaagcttgt tttaagcggt tataggcgag
    68341 ttgtaatctc tattcatctc attagcaaat aacttgccga aaagtctact gaaattaaag
    68401 cagatagtgg aagaattatt tagccaggat agacactatt tgtgaaacac atgtctttac
    68461 ttttgaaatt ctatgatgaa aagccttgga atacagtagc tcttaattgg taatactttt
    68521 tccattataa ataacctctt ttcattttat atttatcccc tctaaaaata atatctaatc
    68581 taatatttta aacttatatt tccctcgctg tgctaataga gcattactaa ataaatagaa
    68641 actagaaaaa agcattacgc ctgccagaat aaaccaatta tttgtat
//
LOCUS       DAFEKH010000008        63060 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.008, whole genome shotgun sequence.
ACCESSION   DAFEKH010000008
VERSION     DAFEKH010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 63060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63060
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.008"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(60..404)
                     /locus_tag="LP386_000594"
     CDS             complement(60..404)
                     /locus_tag="LP386_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HBL1917856.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(541..1686)
                     /locus_tag="LP386_000595"
     CDS             complement(541..1686)
                     /locus_tag="LP386_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBL1917857.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(1866..2840)
                     /locus_tag="LP386_000596"
     CDS             complement(1866..2840)
                     /locus_tag="LP386_000596"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBL1917858.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(2920..3795)
                     /locus_tag="LP386_000597"
     CDS             complement(2920..3795)
                     /locus_tag="LP386_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HBL1917859.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            3925..5832
                     /locus_tag="LP386_000598"
     CDS             3925..5832
                     /locus_tag="LP386_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HBL1917860.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRALSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(6373..9651)
                     /locus_tag="LP386_000599"
     CDS             complement(6373..9651)
                     /locus_tag="LP386_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HBL1917861.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(9922..10467)
                     /locus_tag="LP386_000600"
     CDS             complement(9922..10467)
                     /locus_tag="LP386_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBL1917862.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(10479..11171)
                     /locus_tag="LP386_000601"
     CDS             complement(10479..11171)
                     /locus_tag="LP386_000601"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HBL1917863.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(11190..11474)
                     /locus_tag="LP386_000602"
     CDS             complement(11190..11474)
                     /locus_tag="LP386_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917864.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(11487..12050)
                     /locus_tag="LP386_000603"
     CDS             complement(11487..12050)
                     /locus_tag="LP386_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBL1917865.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            12278..12940
                     /locus_tag="LP386_000604"
     CDS             12278..12940
                     /locus_tag="LP386_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HBL1917866.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            13064..14260
                     /locus_tag="LP386_000605"
     CDS             13064..14260
                     /locus_tag="LP386_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBL1917867.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(14361..15737)
                     /locus_tag="LP386_000606"
     CDS             complement(14361..15737)
                     /locus_tag="LP386_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1917868.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(15774..16640)
                     /locus_tag="LP386_000607"
     CDS             complement(15774..16640)
                     /locus_tag="LP386_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HBL1917869.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSISQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(16729..17754)
                     /locus_tag="LP386_000608"
     CDS             complement(16729..17754)
                     /locus_tag="LP386_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBL1917870.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(17772..18446)
                     /locus_tag="LP386_000609"
     CDS             complement(17772..18446)
                     /locus_tag="LP386_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1917871.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDNNLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(18630..19523)
                     /locus_tag="LP386_000610"
     CDS             complement(18630..19523)
                     /locus_tag="LP386_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL1917872.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(19597..21294)
                     /locus_tag="LP386_000611"
     CDS             complement(19597..21294)
                     /locus_tag="LP386_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBL1917873.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(21287..22600)
                     /locus_tag="LP386_000612"
     CDS             complement(21287..22600)
                     /locus_tag="LP386_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBL1917874.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(22600..26637)
                     /locus_tag="LP386_000613"
     CDS             complement(22600..26637)
                     /locus_tag="LP386_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBL1917875.1"
                     /translation="MVVDERIDNQELQENETDTEDSAEIQRSEENEMEKLDEPIVPSG
                     QALQRIQRQLFNGILERLGPTATQDPYEYIYPSGEVENEQHRYPKFTTNDYTKVLGNW
                     TQSNERYQGDKGSPYDGENLIDDSDYTNGGANWRNYDYATNNGSTAGEEDRNVPAQTV
                     QLWGNERNFENSYLDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEKK
                     EISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMVN
                     FYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETLY
                     KDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDVL
                     FRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGSS
                     NNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAIG
                     RNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVSP
                     FGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYKF
                     SPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSSS
                     IRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFETK
                     MPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEYT
                     SGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNIN
                     KLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDGK
                     YVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRLY
                     DNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTLD
                     GAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQPL
                     HLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIIDG
                     VLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPNDS
                     SLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTLK
                     VEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYILL
                     AAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(26650..27108)
                     /locus_tag="LP386_000614"
     CDS             complement(26650..27108)
                     /locus_tag="LP386_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL1917876.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(27406..27924)
                     /locus_tag="LP386_000615"
     CDS             complement(27406..27924)
                     /locus_tag="LP386_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBL1917877.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(27926..28543)
                     /locus_tag="LP386_000616"
     CDS             complement(27926..28543)
                     /locus_tag="LP386_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBL1917878.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(28540..29403)
                     /locus_tag="LP386_000617"
     CDS             complement(28540..29403)
                     /locus_tag="LP386_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL1917879.1"
                     /translation="MTANDGLFQKDQCESANKKILSYVLMTVIGIILIIPLLWMVFTS
                     LKPMEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFI
                     AYGFAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGN
                     AFNIFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWN
                     DFLGPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFI
                     EGMDLTGGSKG"
     gene            complement(29390..30292)
                     /locus_tag="LP386_000618"
     CDS             complement(29390..30292)
                     /locus_tag="LP386_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1917880.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAGYAMAMSMILFLI
                     VLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(30333..31667)
                     /locus_tag="LP386_000619"
     CDS             complement(30333..31667)
                     /locus_tag="LP386_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL1917881.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKIFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            31875..32705
                     /locus_tag="LP386_000620"
     CDS             31875..32705
                     /locus_tag="LP386_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBL1917882.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(32949..33267)
                     /locus_tag="LP386_000621"
                     /pseudo
     CDS             complement(32949..33267)
                     /locus_tag="LP386_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028215.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(33389..33583)
                     /locus_tag="LP386_000622"
     CDS             complement(33389..33583)
                     /locus_tag="LP386_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917883.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(34088..34273)
                     /locus_tag="LP386_000623"
     CDS             complement(34088..34273)
                     /locus_tag="LP386_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917884.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(35123..35464)
                     /locus_tag="LP386_000624"
     CDS             complement(35123..35464)
                     /locus_tag="LP386_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBL1917885.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(35464..35694)
                     /locus_tag="LP386_000625"
     CDS             complement(35464..35694)
                     /locus_tag="LP386_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL1917886.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            35981..36319
                     /locus_tag="LP386_000626"
     CDS             35981..36319
                     /locus_tag="LP386_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917887.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(36524..36763)
                     /locus_tag="LP386_000627"
     CDS             complement(36524..36763)
                     /locus_tag="LP386_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBL1917888.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(36739..37086)
                     /locus_tag="LP386_000628"
     CDS             complement(36739..37086)
                     /locus_tag="LP386_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBL1917889.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(37818..38399)
                     /locus_tag="LP386_000629"
     CDS             complement(37818..38399)
                     /locus_tag="LP386_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL1917890.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(38582..39208)
                     /locus_tag="LP386_000630"
     CDS             complement(38582..39208)
                     /locus_tag="LP386_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBL1917891.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(39230..40561)
                     /locus_tag="LP386_000631"
     CDS             complement(39230..40561)
                     /locus_tag="LP386_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HBL1917892.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(40716..41117)
                     /locus_tag="LP386_000632"
     CDS             complement(40716..41117)
                     /locus_tag="LP386_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBL1917893.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(41203..41409)
                     /locus_tag="LP386_000633"
     CDS             complement(41203..41409)
                     /locus_tag="LP386_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917894.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(41504..43006)
                     /locus_tag="LP386_000634"
     CDS             complement(41504..43006)
                     /locus_tag="LP386_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HBL1917895.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(43024..43479)
                     /gene="argR"
                     /locus_tag="LP386_000635"
     CDS             complement(43024..43479)
                     /gene="argR"
                     /locus_tag="LP386_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBL1917896.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(43577..44194)
                     /locus_tag="LP386_000636"
     CDS             complement(43577..44194)
                     /locus_tag="LP386_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBL1917897.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            44415..45788
                     /locus_tag="LP386_000637"
     CDS             44415..45788
                     /locus_tag="LP386_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL1917898.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            45863..46975
                     /locus_tag="LP386_000638"
     CDS             45863..46975
                     /locus_tag="LP386_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBL1917899.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(47047..48684)
                     /locus_tag="LP386_000639"
     CDS             complement(47047..48684)
                     /locus_tag="LP386_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HBL1917900.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(48852..49460)
                     /locus_tag="LP386_000640"
     CDS             complement(48852..49460)
                     /locus_tag="LP386_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL1917901.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(49844..50995)
                     /gene="queG"
                     /locus_tag="LP386_000641"
     CDS             complement(49844..50995)
                     /gene="queG"
                     /locus_tag="LP386_000641"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HBL1917902.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(51014..51766)
                     /locus_tag="LP386_000642"
     CDS             complement(51014..51766)
                     /locus_tag="LP386_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917903.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(51907..52857)
                     /locus_tag="LP386_000643"
     CDS             complement(51907..52857)
                     /locus_tag="LP386_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBL1917904.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(52858..53697)
                     /locus_tag="LP386_000644"
     CDS             complement(52858..53697)
                     /locus_tag="LP386_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBL1917905.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(53694..54440)
                     /locus_tag="LP386_000645"
     CDS             complement(53694..54440)
                     /locus_tag="LP386_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBL1917906.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            54678..56048
                     /locus_tag="LP386_000646"
     CDS             54678..56048
                     /locus_tag="LP386_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1917907.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(56103..56999)
                     /locus_tag="LP386_000647"
     CDS             complement(56103..56999)
                     /locus_tag="LP386_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL1917908.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(57113..57283)
                     /locus_tag="LP386_000648"
     CDS             complement(57113..57283)
                     /locus_tag="LP386_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917909.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(57280..57957)
                     /locus_tag="LP386_000649"
     CDS             complement(57280..57957)
                     /locus_tag="LP386_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBL1917910.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(58048..58953)
                     /locus_tag="LP386_000650"
     CDS             complement(58048..58953)
                     /locus_tag="LP386_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBL1917911.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            59128..60567
                     /locus_tag="LP386_000651"
     CDS             59128..60567
                     /locus_tag="LP386_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL1917912.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANVATTALLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELPMQ"
     gene            60597..61628
                     /locus_tag="LP386_000652"
     CDS             60597..61628
                     /locus_tag="LP386_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBL1917913.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            61635..62822
                     /locus_tag="LP386_000653"
     CDS             61635..62822
                     /locus_tag="LP386_000653"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HBL1917914.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
BASE COUNT        17985 a        13213 c        11178 g        20684 t
ORIGIN      
        1 aaagttagtc atctaacaat aggccgtttc aaaactagtt gtctttttat atccacagat
       61 cattcgactt tttcgaataa cccacggcta atcatcccat ccatcagaaa ataaaattta
      121 tcttggctca ttttctgttt tggatctttg aaaatattga ctgctttcaa tccatttgct
      181 gtagtgatcg acattttcaa tgtttgaata tcttttgata cagtgatttt taatttgaat
      241 ccttctttgc tttgcggcgt ggcatctaat ggtcggatca attgataatt gcctccgttt
      301 gtttctgtaa atccattatc gcgcaatgta tatctttttg catcaggatg caaacgatag
      361 ctaattggtg cgcccagtac cgttgctgtt gtttcaaatg ccatgatttt cacctcgata
      421 aaattagttt ctctttatta taaaagttta tcctgatttt tactaggttt ttcagttaag
      481 ttccctaaaa aatgaaggcg ttctctcaga catctgttca tataagaatg acttcactag
      541 ttattttttg acagcacgaa ctaattgatc aaggaaatac tggatgtcgt cttcggtatt
      601 tcccaaacca aagctgatac ggatggattc ttttagtatc ggtgtatctt ctccatacat
      661 tgcttctaat acgtgtgaag gctcgatatt tcctgctgta caagctgaac cagtagaaat
      721 agcgacccca ttaagatcaa gcttcatcag tagcaaatca tttgcttcgc caattaagcg
      781 aagattcaac acatgaggga gtttattcgt taaatcacca tttacttgat aagggatttc
      841 gtttgcttct aatgtatcaa gaatcaattg ctggaatcct ttatatttgt tgttacgtgc
      901 ttcacgttct tcaggtgaca gcagttcaac tgcttttgcc ataccccaga tccctgctaa
      961 attttctgta cctgcacgcc gcttttcttc ctgctccccg cctaaaagca atgcagggat
     1021 atttactccg tctcgtttat ataagaaacc gacgcctttt ggcccattga ttttatgagc
     1081 agagatactt aataaatcga ttcctaattc ttctggatgg atcgtttggt ttccgtacgc
     1141 ttgtaccgca tctgtatgga aataagctgg atgatccgct aaaagttcac cgatttcttt
     1201 gattggcatc aaatttccga tttcattgtt cccgtacatc acagagacca agatcgtatc
     1261 ttctcgtaac gcttttttga cctcttcgat cgacagattc cctttttcat ctacaggcag
     1321 atatgtaacg tcaaacccct ttgtctctaa atatttcatg gtattaagaa cagcaggatg
     1381 ttcgatagct gtagtgatta gatgtctgcc ttctttttga cgcgagaacg ctgtttctaa
     1441 gatagctgta ttatcccctt ctgttccccc actgttaaag atgatctcgt gaggttttgc
     1501 ttgcagactg tctgcaatga tttgtcttgc tgtttccaat ttttcatgcg cgtggcgacc
     1561 aaatccatgt atgcttgaag gatttccaaa cgtgtcttgc atgattgccg tcatcgcttc
     1621 aattacttgt ggatgcatgg gggtagttgc cgcatgatcc agataaatag ttttcacttc
     1681 attcatccct tccaaattat tgctaggcac attctagcat aaaatagcga acaaaccaaa
     1741 gaagagctca tttttgtcta gaggacgttt catgggcata gaaaaaagga gctgtgacaa
     1801 aagtcttgtc gcagctcctt gaagctgctc acttctgtca caacttcttt ccctcttttt
     1861 tttgtttatt cgaattcttt ttcttccaga cggaataacg gactcatcgg tgtattttca
     1921 tggatgcgtt tgaccgcttc acccattaat tctgaacatg taacgattgt taagttttct
     1981 ggatgacgat tttcttctgt gaaaacagaa tcagtgatac aaatatcttt gattggtgca
     2041 ttgtctaaaa tacttttcgc atgatcggac aataatccat gtgacgcaca ggcatatact
     2101 tcttttgcgc cgttttcttt taatacattt gctgctcgtg caagcgttgc tcctgtgttc
     2161 aagatatcat ctaccatgat acatgtcttt ccttgaacat caccgatcac ataaccaccc
     2221 tcagttgaag catcatctgc atgatctacg atggctaatg tgctgttcaa atattctgaa
     2281 agactacgtg cacgctgaac accgctgttt tttggcgaaa caactacgat gtcatctccc
     2341 gtcagaccta attgacggta ataatgagca aacaacggca tcgtaaataa attatctaca
     2401 ggaatatcaa agaatccttg tacttgaacc gtgtgcagat ctaaagtcag tactcgagtt
     2461 gcccctgctt cttcgatcaa gttagcgatc aatttcgcag tgatcggttc atgaggtttc
     2521 gccgtgcggt cttgcctagc atacccatag taaggcaata cgacattgat cgttttcgca
     2581 cttgctcgct tcattgcatc gatcatgatc agtagttcca tatagtaatc attgacaggt
     2641 gcattcgttg attgaacgat atacacatga tcccctcgaa tactttcttc gatattgatg
     2701 gaaatctcgc catcactaaa ttgcttcacg acgcttttac ctaattctgt tccgaacact
     2761 ttcgcgattt tttcagctaa tggacggttg ccattcaaac taaaaatctt caacgtgtca
     2821 tcctgatact tattactcat gtagtcctcc ccaaaacttc tctattcttc gatagtttaa
     2881 catatttttc caagattttc tgttaatttc agcaaattct taaggaagtg aaactgttcc
     2941 gttactccaa ctggcaggaa tgactttatg ataatcgccc cagttgtcgt gtactttgta
     3001 ataacgttct cctgtttcag tttcaaaata agcgtacgct gtcacccaat gattgccata
     3061 tgtactgcca agtactttca aaataccaat catcacaggt ttgccttcac gtatacgttt
     3121 tgtagctcgc tgccatgaac ctagaagagt tgctcgtgca cgctcatgat tgccattctt
     3181 ctttaaaaaa ctagaaatcc ctgtactaac ctgaaaagga atcgtaggaa gtcctagtgg
     3241 ttggatctgg ctacgcaatg ccttcgtcaa aaccaacgaa tcagccgtat ttttcttgcg
     3301 aatctcattt ggaagcatcc accccttacg atagtcttga taataggcaa ggagaactgc
     3361 tgccgcgtaa gtaccacaaa gatagcctga gggggtagcc catttcttat acctcaaaaa
     3421 acgttcttct ggcaatccca cccagcaatt tgcgagttcc tttcctgacc ttttttcttc
     3481 gatcaaaacg ggaatatctt cttttctgtt gatccatcta gataactcga ttggctcttc
     3541 attgatcagc ttccattttt tacaagaaag accctcttga taagtatatt ttgctggaga
     3601 atattctacc ggatgtcctg attgatcgat aatcacataa ctttgatctt caaaaaccag
     3661 agctaaaaaa agcaatttac tttttcttga ctgcagctgc tgagtgctgg ctaatttttt
     3721 aattttttta tctactttga aatataaagg tttatccact acttgattca gttgggatcg
     3781 cctccttttt ttcattataa gtgaaggatt gaaaaaaaca aatcagtttg attgttcgaa
     3841 ttttcaattt tttatgttct atttgttaat tccttcattt tgtaagataa tgggcacacg
     3901 aaacaaaaaa ggagcgatcg atgaatgaac aaagaacgat tgaaacaaga tttctatgaa
     3961 gcagtcaatg aagaatggca aaaaacagca aaaatccctg cagataaacc agctacaggc
     4021 ggtttccaag atttagttga cgggatcgac caacttttga tgggagaaac agacgatctg
     4081 cttgcccatc cagaaaaagt gtcttcagaa aaaatgaaac atttccttgc atattatcaa
     4141 ctggcaaacg attatgaccg aagaaatgag ttgcatgctc aaccgcttca acctataatc
     4201 gaaaaagttg aatcattgca gtctttcgac gaattgaata agcaatttcc agaatggctg
     4261 ttggatacat taccattgcc atttaatctg gatgtagatg cagatatgaa gaatgcgcaa
     4321 acgaacgcct tctttgctta tccgccttct ttattccttc cagataagac gtattatgca
     4381 tcagaccatc ccaacggtgc acaactaata ggcgttttct ttgatatggc tgttcagtta
     4441 ttagagcttg ccggcaaaga aaaaagtcag gcagaagcaa tcacggaaca agcagtgcaa
     4501 tttgataaat tgattgctcc tcatgtaaaa agtgcagaag aaaacgcaga ttacagcaaa
     4561 atgtataatc cgcaatcttt tgatacattt attaaataca cagataaact ggacttgaaa
     4621 aaacttgtca cgggtttgat tgggacaact ccagataaag tgatcgtaac tgatccagtg
     4681 tacttcgatc atttgaatga catcctgaca gaagctcatt ttccgttatt caaaagctgg
     4741 atgatcatta aaacagtacg ttctcttagt ggttatctat cagaagaatt ccgccaagtc
     4801 agcggaatct attctcgcgc attgtctgga acagacgaag caatgcctca gaaaaaagca
     4861 gcgtattacc ttgcctctgg acaattcgat caagtagttg gcgattacta cggaaaaaaa
     4921 tattttggcg aagctgctaa aaaagacgta gaacaaatgg tgaaaaaaat gatcgccgtt
     4981 tataaaaaac gtctagaaga aaatgactgg cttggggatg caacaaaaga aaaagccgtc
     5041 ataaaattaa ataacttagg tatccaagta ggctaccccg ataagatccc agcattattc
     5101 gaccagttca aaacagtacc tgcagatcag ggtggtactt tgctttcaaa tactcttgtt
     5161 ttcagcaaac tcacattaaa agatcgtttc agcaaatgga acaaaccagt ggatcgttca
     5221 gaatgggaaa tgagtgctga cacggtcaat gcttattatc atccatttcg gaatgtgatc
     5281 gtctttccgg cagcgatcct tcaagcacca ttttacagtc tagaacaatc aagctctgct
     5341 aattatggtg gaatcggagc tgttatcgct catgagattt cccatgcatt tgataataac
     5401 ggcgctttat ttgacgaata tggcaacttg aacaactggt ggacagaaga agatcttaca
     5461 caatttcaaa acaaagcaca agcaatgatc gaagaattcg atggtctgcc ttttgctgac
     5521 ggaaaagtaa acggaaaatt aaccgtttcg gaaaatattg ctgatgcagg cggtctaagc
     5581 tgtgcattgg aagcagcaaa aacggaatca gatctttcta tcgaggaatt ctttgtcaat
     5641 tgggcaacga tttggcgtac aaaagcaaaa aaagaatacc aacaactttt actgcaaatc
     5701 gatgtccatg cccctgctaa actccgagca aacgtgcaac caaaaaacct tgacgaattc
     5761 tatgaaacat ttggtatcac ggaacaagac gctatgtatc tagcgccaga aaaaagagtg
     5821 cgaatctggt aagaggttgt gccagaagtg gtcagcttca agaaataaga aggaatttgg
     5881 gaaaatcgct tctcaaattt ttgtgacatt tcggcttatt tttcgaagaa gttacttctg
     5941 gaataccatg tattagaggt tgtgaaaaag ctgcttagtt tcaagtagta agaaaaattt
     6001 tgtgaaaatg gctttccaca tttttgcata aatttgactt actaccgaga aactggcttt
     6061 tgaacaccgt ttatcgagag gttgtgaaat cagcgtcctg acctgagtat tagagaaaaa
     6121 aacggaaaaa tagttcctca tattttgccg tttgttgagc taataccgag ggtcagctga
     6181 ttgaacaccg tttagtggag agattgtgaa aaagctgtcc tgcatcaagt aataagaaca
     6241 gccaatcaaa agcagcaagg agaacctcat ctataaaaag atagaaggaa gtgagacatc
     6301 tattggtctc atttccttct atttttactt tcctcagtca attgttttac atcataaaag
     6361 gagaaattcc acttattttt ttcgctgttt catgacataa acaactacac cgattaacaa
     6421 aattcctcca gctaatgcta gcaacgggtt attaaattct cccgtttttg ggagtccttg
     6481 agtgccattt ttttcacttt cttttgctgt cctatccgga tgagaaggtt ttccatttgg
     6541 ttttccattt ggtgattcat ttcctggatt ttctctttct ggtttgtcat ttcccggggg
     6601 cacatcggca gtttctcgca cagtgatcgc tttttgctgg gtaacagatt ctgtatgagc
     6661 agaccatttt tccccatcaa atatttccga acgataagtg acttctagcg tatattctcc
     6721 ttttgaaggt gctgaaaaaa tagcggtatg attagaaaat tgagcacttg actgtgtttc
     6781 aacgatttgg atcttttctg ggaaataacg catatcttca aagacaggcg ttccttgatt
     6841 tggtgtgaaa gttgacacaa aaactgtaaa aggcttcagt tcaatgatat ttccttctgc
     6901 attctccgcc acaccatttg cttcttgtat aataatcgga ttattttgtt catttggttt
     6961 tgtctgattt ggttcttgta cgattgcata ctctggatat tccgaagacg gtgaggtttc
     7021 tccgtcaaaa atagcaccta cagataatgg aagaccatcc actctttcct tttctgtttg
     7081 acgattcccc ggtttaatct gcatcagtcc atgaacatgg atacttccat tttcatagcg
     7141 cgtaacaggc tgctgacctt ctttcgaaca tgtatttaga gactcgatcc aatcttttga
     7201 tatggtatgt ccaagagtat tttctgattg tttctctcgt tcattccaat agtagttcaa
     7261 cgagtggtag atttgatctt cgttttgatt caatgggcgg atctgctctc tcatctcaag
     7321 attctctgtt cggaaagata agataccaga agcatggtag tctgtgtttc ctgctgaaga
     7381 ggtataaaga gccacattat atgaaccgtt attaaaactt gtactgctat tgacgataat
     7441 atctgttccg ctattggaat cgattccttt cgcaagattt tcgaaagaca aactattgat
     7501 caattcatga gggcccgtta aagaagaacc gcccattttg aatccattac cgttaccttc
     7561 tccctcaatt cctggtaccc agccgtttcg ataagcaact gagtttttga tgattacttt
     7621 tccgatcgaa cctgtttcat ttttagcaaa aaggtcccaa ccgtcatctg cattatgata
     7681 cgcgatacaa ccgtcaaata catttccttc tcctattgtc agtttggccg caaatccatc
     7741 ggcatcttca aatcctggat cggcattttc aaaagatgta cagttcttga ctaagttatg
     7801 cgcgggccat gcttcgaaag gatcatttga gctaccgctg atttggattc ctgtatttcc
     7861 attccgataa gcatgaatct cttcgatcaa attatgattt ccagaaatct gtaatccttt
     7921 ttgcatagct gcactatttg taatgtcaaa ccctcgtaaa ccccagtagt gactgaacag
     7981 tgtcatccca tttccagttc ctttaaaatc aagtacagga cgcttgtttt ctggattttt
     8041 ctctgcaatc aactgaatcg ggttttctct tgtcccgtta acgccttttg gaatcgtcaa
     8101 tcctctttcg aaggaataag ttccaggcgc catgacgatt gtctgcccag catatgcgta
     8161 tctcaatgct tgtgtcagag ataatggatt ttgtctgctt ccgtttcctg catctgaccc
     8221 ttctggtgtt acataaactg tcgaatattt aggtttacgg tagtccactg tatgaagaat
     8281 ctcttttgtt tcataactag tcatctctac gtattcttct ggcggatagt ttttatctgg
     8341 cgtaaaactg aaagtaaatt cgttcgttcc ttccatcagt tttgtctgat aatcaaattc
     8401 ccgattcgca gtgatagcca agttttttgc gttcttaagc acctctcctg ttgctttatt
     8461 tttaattgtc aataatccgt cagcatttgc tctaaaggac atagtatgat cttggtttcc
     8521 tgaatgatta ctagaggtca cagtgtaaat cggatcaatc aagcgagtag gtctttcttg
     8581 cccaggagga tctgtcgcag gatctgagta agcaacttcg attccttcta ccttgatcgt
     8641 catattcctt gctgcagcaa atcctgcata aataaccgat tcatctgaag cgtataattt
     8701 ttcccagtca tacatgatgt cagaagccat ttcttctcct gtttcaggat cgtaataata
     8761 tgcctctaaa ccagtattcg tttttttcat ctctacgtcc agtttagtaa tcgagttcgt
     8821 ggccggaaac agattcccat gaccgtttcc gaatatatta taagaacctg tttctttttc
     8881 caagaaccct gctgaagtct ctaaaggtgt tgtttccact gagacactcc caggagctgg
     8941 cgcagcttgc ggatcttcag atgatattcc tgtgattgcc cgtgtcccca atccaagtcg
     9001 catcgtatat ttgctgccgc tcgtgttgac cacttcttgt ctatccgagt cccagacata
     9061 ttcgatccga ctgcctagta tggcaaatga atttgaataa aatgcctgcc caaacaaatg
     9121 attttttggt actgcgtctc ttaccattaa agcaaatcct tcttgggcat tcgtataggt
     9181 ccaagattct atttcgatcg tcgcccgcat cctaaagttg atgtctttgg ggattgcttg
     9241 ataataatag gtcattccat ctgatccgct tgactggaat tttccgccgt tattcgtgga
     9301 agagagccgc acgccgtctt ctaatggttc aatggcatac ctactagcac ttgtgctttc
     9361 tccgaaaaca acccctttcc actcttcatt tgcttcttca gattgctttt ttgtcttttc
     9421 attttctgat tctttcatca taggatcatt tccttcttcc gtatccatat cttcactagt
     9481 tcttggtatt tcctccattg ttgacatccc ttcaatgttc acgtgtgcat tttcttcgtt
     9541 cacagactgt tgttcgttag cagcaacttc aacgacagaa attaaaaccg gggtactgag
     9601 cataaggaga ttcatcatta gcgcactgta ttttatacgt ttttttaaca agtgtattcc
     9661 tcccgtaaca aattagaaag cgtttactta aagtattacc taatttattt ttactgtcaa
     9721 taaaaaacaa aattataata agtgtatttt ataaaaagaa aaaatataac ttaagttgtt
     9781 gataataaag agatttatta acggaaaaag aataagtttt tttaaaataa cgtataaaaa
     9841 agagcataaa acaaagtcgt ttgttttatg ctcttctttt attattttgt gctttttatt
     9901 ttatcaaatc actttgtttt tttataaaat ttctgcgcct agtgtggact caaaatgtct
     9961 caatgcccat tcatgtccaa cgggatcgaa acttgccacg gaatctttga aaatatggag
    10021 tttgtatcct agattatacg catcgactgc tgtatgcaac acacagatat ctgtacatac
    10081 gccggtcaaa taaatatctg tgatctggcg ttctcgcaaa cggatgtcta gatctgttcc
    10141 actaaaagcg gaataatgcc gtttgtctat ccaataaaca ttttcctctt gctcatagtc
    10201 ttggtataaa ctttttaaag agccgtacaa ttcccgtcca cccgttccta tcacattatg
    10261 cggaggaaat aagcggttct ccggatgaaa ggaatctttt ggatcatgcg catcaatggc
    10321 aaaaacgaca aaatcctttt gatcaataaa cttctttgta tgagcagtca gctttttttc
    10381 aattacttgt cctgctgtcc cagtagtcag ctttccatcc tctgcaacaa aatcatatgt
    10441 gtagtcaatc gagatcaatg cgttcatctt agtcctcctt atacgagatg tttgacaaat
    10501 tcgatcacca tttctgctga tcgtttgcct gcgtcttcga taaattcgtc aaagctttgt
    10561 gtcgccgagt gatctgctgt gtcgctcatt gcacgtacga tcaaaaatgg gatattgaac
    10621 tgacgagctg tttgtccaac agcggctcct tccatttcgc aagctaatgc ttcagggaaa
    10681 ttcgttaaga tttctttgat tttatctggc gagtcgacaa atgtatcacc tgtaacgatc
    10741 aatccttctt ttgcgttcaa attcgttgct tttgctgctt taaccatttc actgcgcaaa
    10801 tatgtgcttg cttcataata tagaggcatt cctggtaatt gtcctgggtt gtagccaaat
    10861 cctgttgcat ctgcatcaaa ataagctact ttgtctgata taacgatgtc acctacttgt
    10921 aagccttcac cgattccgcc agctgaacct gtattgatca ccatgttcac gccgtattgt
    10981 tggatcaaca gacttgtggt aatagatgct aagacttttc ctataccgga acgtacgacg
    11041 atcacttcgt ggttacctaa tgaacctgaa ataaataaag cgcctgcgcg ttcccatgat
    11101 aatggttcgc ttaggttctc tctcaaaatt tttacttctt cttccattgc gccgataata
    11161 ccgattttca tctttttaat tccttctttc tatataaatg cgattgctaa aaaaaccaca
    11221 cataacatta ggataacaat aataagagat ttcatcaaaa aagagttcca tttggtcgtc
    11281 ttttcccgtt cgctgatcct tgttttcgtg attggtttat tctttttgct ttctttacga
    11341 taaaagctgg caatcttttt ttcttcttgc tgataagctg tttctgcttt tcgctgtttt
    11401 tttaatgact cgcttgcttg tgcttgttgt cgcttgcgaa gttcgcttcg cgtaataagc
    11461 ggtcctttgg ccataagccg atccctctac tttcctttgg tcaatagttc ccagtattga
    11521 atcgcataaa tcgtctttgc atcacaaatc aactgatctt tcatcgcttg ttgcgcctct
    11581 tcaagagtta gatgatacaa ctccagtact tcgtcttcat cttgtgctaa aggattctcg
    11641 accttctcta ccccttgtgc atgataaata tgaaggactt catttgcaaa acctggtgaa
    11701 agatacatcg aagtaagatg gctcagcgac ttcgcacgat agccagtttc ttcttctaat
    11761 tctctagctg ctgtcatttc gggattttgt ccttctcctg gatcgatttt tccagctgga
    11821 atctccaaaa tcactttttc taaaggtttt cgaaattgtt tgacaagaag cagacgatct
    11881 tgttcgtcaa aagcaatgat cccgacaccg ccaggatgaa ataccagttc tctcttcgaa
    11941 gttcctccat ctggcaaacg aacttcgtct acagcaacat caataatttt tccgctatag
    12001 atttctttgc gactgattgt tttttcttca aattgctcat tgttcagcat atcttctcct
    12061 gctttctttg taatcataac tgcttttttt tcatttttca atttttctca aaaactcctt
    12121 attagtttac catagataaa ccttagattt tctctaaata tagaaaatcc ttctttagtc
    12181 cgatactctt tctagtagtc cgtatgctaa aataagtatg taatcgaata acgaaaagaa
    12241 ttcaatactc aacgataaat gacatggagg gtttattatg ataaaacgaa attggccgtg
    12301 gcttctagca ttggtcttgc tatttctctt tgtccgaaac aatagttttt cttttgttct
    12361 aggactttta ttgataggtg tagttttagt tttgtgggga ctctttggtt cgcgcaggaa
    12421 aaagggaaaa caagaagaaa ttcctgcact gactgacgaa cttgaaactc actatgaaaa
    12481 aagcggtatg acagcgaatg aaatttcatt ttttcgacaa acaatgaatc aaacaaaaaa
    12541 tgagatcaat caattgcaaa tgaatatgca gcagacagcc aaacttaaag caatcgatct
    12601 ccgccatgat ccagtcaaag cagcgaaagc tttattcaaa gaattggtga aagaaccaaa
    12661 ccgactgcat gaagcaagtc agtttcttta tacgcatctg ccgaatctag ttgatttgac
    12721 aaataagtat aatgagatca atgaccatga gatcaaaaac aaacagacct atgaaaaact
    12781 agaagaaagc gcgcagatca tcgaccagct gtcagcttta atcgcacaag attatcaaaa
    12841 attcgttgct gaggatctag atgatatcga cgtagagata tctgttgcga aacagagctt
    12901 aaagcgtgat aataaatatg aaccagaaca aaaggattaa ctcttttgtt cataaaagaa
    12961 gactcggaac attcagatga tgtctggctg tttcgagtac tttttctaaa gtagagacat
    13021 tcatgtaaga atcgagaaca gattcaacaa ggaggaattt tttatggatc ataaaccgac
    13081 tgaaacaaaa gatgttacac cagttaacga tacacttgaa gatttattga acaacccgtt
    13141 ttcaactcca acagatacgc tgaccacttc acaacaagcg gagattgatc agctccaaga
    13201 gcaacagaca gctgctcgtt taattgacaa actaccggcg gaacgccaag aacaagctaa
    13261 acagctagca gcaaaaatcg atgctaatga tgcacagtct gtcatcagct acggatcggc
    13321 tgcccaagca aaattaagtg aattctcaca atcgatgttg aatcatgtgc aagcacaaga
    13381 tattggtcct gtaggagatt ccttaactga actgatgtat cgtctccaag aagccaatcc
    13441 tgacgaactg cgtgccggag aagggaacat cttccagcgt gtcttcggga aggtcaaaca
    13501 atcgatctat gaagtgacag caaaatatca aaagattggt gcacaaattg acaagatttc
    13561 agtgaaatta gataaagaaa aagacggtct gctaaaagat aatctgatgt tagaacagct
    13621 ttaccagaaa aacaaagact actttgatgc actgaatatt tatatcgctg ctggagaatt
    13681 gaaaatggaa gaacttcaaa caacgatcat tccagaagcg atgaaaagag cagaagaaac
    13741 tggcgatcag atggatgttc agattgccaa tgattacacg caattcctag atcgtctgga
    13801 taaacgtacg catgatcttc gcttagctag acagatcacg atccagcaag caccacaaat
    13861 ccgtttgatc caaaacacaa atcaggcctt ggctgaaaag atccaagcat ctatcgctac
    13921 agccattccg ctgtggaaaa accaagtcgt gatcgcattg accttgcttc gtcaaaaaga
    13981 tgcagtaact gctcaacgcc aagtctctga aacaacaaac gacttattga agaaaaattc
    14041 agaaatgctg aaaatctcag ccatcgaaac agcgaaagaa aatgaacgtg gaatcgtgga
    14101 tatcgagacc cttcaaacca ctcaaaatga tttgatcgaa acaatccaag agacattgcg
    14161 tatccaaaaa gaaggaaaag aaaaacgtcg tcatgcagaa gtagagcttg gacacatgga
    14221 agaagatctg aaacaaaaac tgttggattt aacccaatag atcacctttc gcttgttact
    14281 aaaacaaacg cccaacaaca gtttattaca actgttgatg ggcgtttttc ttatctttct
    14341 tctaacttct ccattggagt ctatttctca ttcatcttgc tgtgtccata gccatagcca
    14401 aaataaatga tcagtccaat aaccattacg ataccgaaca cgatccatgt cacagtttgc
    14461 agacgaagca tcaatacaat acaagtcaag atggagacga ttggcaatag cggaacgaat
    14521 ggcactttga attctccagc ttttggtttg ccaaacattt ttctcaactt cagtaagcct
    14581 agactaacaa gcatcaaata ggcgagcgcc atgatattcg ttagttccgc taatacattc
    14641 aatgggaaaa atccggcaaa gaatacagct gccacaccag cggcataagt cgcttttttc
    14701 ggtgtacgat gcttttgatc gatttctgtc ataaacttag gaagtaagcc atccttgctg
    14761 acagcaaaca gtaaacgagc aagtgaatac atcatcgaga tcgttaccgt cagtagcgtt
    14821 aaaattgccc ctacagcgat caccgcgccc actgttccat gtcctacata cctcattgca
    14881 aaagccactg ggtcattgac tcctagttca gtatacggaa cgattcctgt caagatcagc
    14941 gtcacgatga tgtaaaggac agtagcaatc agtatcgaac caatgattcc tcttggcaca
    15001 tctttttgcg ggtttttgac ttcctcggct gccattgcaa cggcatcaaa tcccaagaaa
    15061 gcaaaaaaca caagagctgc accatctagc acaccggaaa aaccaaaagg catgaatggc
    15121 tgccagttat caggtttaac gaaaaatatt cctacaatga taaacaacgc gatgatacca
    15181 aatttgacat ataccatggc attattcaaa cgtaatgctt tcttggcttc aagcgacacg
    15241 atgtaagtga cgaatatcac tacgagcacc gcaatcaagt caatgtatgt accattttcc
    15301 ggattgtacc cgccagttaa tgcttgtgga agttcggccc ctaaactttt caaaaaacct
    15361 tgcatatagc cagaccatcc ggaagcaaca gaggaaaccg ctagtaaaaa ttccccgatc
    15421 aacaaccacc ctgtcagcca ggcagcaaat tcaccaaata caacatacag ataggcatat
    15481 ggcccaccaa tcactggcac tcgcgaagca aattctgcga aacttagtcc agacaaaatg
    15541 acaacgattg cagctaagac aaatgaaagt gacagtgctg gaccagcatt ttgattggcc
    15601 gcaacccctg tcaccacaaa tattcccgta ccgatgatcg caccaattcc aagcatgatc
    15661 aaatcagacg tttttagttc ttttttcatc tcactcgtat gattgagatt gatctctttc
    15721 ttacgaaaca aatccattga agttcctccc cattttaggt tggaaaacag cgattaaact
    15781 gttttcatat accctaaaag gataccacct aaaatgacta aaaggcaacc aacaataaca
    15841 taaatgagct cttttttcgt ttttctttcg ccaaggatga aaatcccacc taaagtagag
    15901 ataatgatcc ccatttgtga aattgagaag ccaacagcta aaccaagtga tttgactgtt
    15961 agaagcatgc agatgtttcc taagccccat aataatccac agatcatgtt tttccacaca
    16021 aactgatcga ctttaacttt acggaaagca aagaagcttg cgcctaagat cattccgata
    16081 ctttgaggta agataattga catcgcatcc aaattcgccc agttgacgat gatggtatat
    16141 acaccataac caatcgtaga gaagatcaat gctctaaaac ccttaccaaa atcaagcatt
    16201 ttattatctg tatctatttt tccttcgtca tcttgtcggg cagtcaaata cgcaccgctt
    16261 acaagaagag ctaaagcaat aataccgtat acataatctt tcgtttgtgt ccattcatgg
    16321 aagaaaacgg ctcccgcaat cgtattcaaa attaattgaa aaccagtaga caatggtagc
    16381 cctacagaaa cacccatgta cttcattcca tggaactgtc cattttgtcc aacactccaa
    16441 gctaagccgg ataaaaatcc gatcaagaaa atccaagggg tgattacagg actaacaacg
    16501 aaaaagacaa ctaaagaaaa cagaaatgca ccgatcgtca ttcctagtgt ttgttgattg
    16561 gcatcgccac caattttacc acttactaaa ccaatactac cccatgccaa catagggact
    16621 aatgctatta aaatttccat aaccaatctc cttttatttc acatgataag aaacttatca
    16681 gcgaaaacgt taacaacaca agcacttttt ttcgtttcta acgattttct aacgtttttc
    16741 attataaaaa tttaagattg ggaaaaataa agtcattgtt gtcccttttc cttcagttga
    16801 ttcagccgtc aaatggatac ctaatttttc ggccagattt tttgctaaat aaagtcctaa
    16861 tcctgttgaa tgtgttttgc taagtcgacc atttctccca gtaaatccct tatcaaagat
    16921 ccgtttcaag tcttccgctg ggataccgat ccctgaatct ttaactgaaa ggctgactcc
    16981 ttgcgcttcc ttttctatgc tcacaatgat gtttccgtga tccggcgtat atttgatggc
    17041 attactaagc aattggttga agataaaagc gatccattta gcatcggtca aaacagtatg
    17101 atcctcacca acgatctcgt agcgaatatt tttttggata aaataatttg cctgactgcg
    17161 tatcacaggc tgaatgattc cttttagtcc atattcttgg atgaggtagt cccgcgagaa
    17221 actgtcgagt cttgcataat acaaaacttg ttctacgtat tcatcgattt ttgataattc
    17281 attttctagt aatgtatact tttgatcgtc aatatcgaac tcgatcgaac gaactagcaa
    17341 tttagaagcg gaaagtggca ctttgatttc atggacccat gagtcaatat aatctttttg
    17401 gtcttgttga ttactgattg ctgattgcat tacttcttgg tgttcacgga tcagctgatt
    17461 gatatattct tctaccagtt tttcttcttc tgtcctccca ccactcaaat aattttgcaa
    17521 aggggaagtt ttttgtatgt cggctaattt tccccaccat cttctcttgc tcaagtaacc
    17581 acccagcaga taaaaaatca gaaagacgcc ctcaatcaaa gctaaataag caattgtgct
    17641 caaatcaact ttgatgtttg gcgccagcca catcacaaag atcgtcaatg caataaaaaa
    17701 cagccatccc aagatcaatg tccactgatc tttcaaatat ttaaaaaaat tcatcttaac
    17761 cgctcatcct ttcagggaac gatatatccc tgtcctactt ttgtttcgat atatccttgg
    17821 atacctgcct gttcgatttt tcggcgtaac cgattgatgt tgactgtcaa tgtattgtca
    17881 tctacaaatc gttcgtcatc ccacagtgct cgcagcaatt tttcccgact taagatcttt
    17941 ccattgtgct tcatcaaaat aaataataga cgatattcat ttttgctcaa atcaatgatc
    18001 tctccgttga tttccatact tccgttgtca acattcaacg taatgccatt gtggctcatc
    18061 atttcactag ataattctgt gtagttgtaa gaacggcgaa gtaatgcatt gatttttgca
    18121 atcagtacat cgatttggaa atgttttgtc acaaaatcat ctgcccccat gttcatagcc
    18181 atgatcatat ccatattcgt attcctgctg gagataaaaa tgatcggtac tttcgatact
    18241 tcacgtattt tttgacacca ataatagcca tccaaaacgg gaagattatt atctagtaat
    18301 acaagctgtg gttcttctct ttcaaagtct gagaacactt gattgaaatc ggtcgttcca
    18361 aaggtttcaa attgccattt ctcaagttcc tccatgatca attgtcgaat gatctcttcg
    18421 tcttcgacta ccatgatttt tgccataaaa aatccctcca tctttcttct tgctactaca
    18481 atatcaaaga agcccttgtg aaacaagttg gcttacctgg aaaatgtcat tttagcaaac
    18541 gttaaaaaaa actggaaata tgcgatttaa tcgcgtttgt ctcttccaag cagcttaaat
    18601 ttattatgtt attcttaata attggtctat tatctgttat ttttctttcg ttgtttttgt
    18661 cttttaaatt ttcgataaca ccaataaccg aaaagcgtta gcactagcaa tatacctaga
    18721 aggagtataa gtaatcgata aagatggtat ttttttgtct gttctatctt tgaagagact
    18781 tcttctgtaa agggaactcg tcttcctgtc actagtaatc ggtgagtgtt cacggtgtaa
    18841 ggtgtacaag tgataagtgt gactagatcc tgcttttctc taattgctaa tgtatttgtt
    18901 tttgttggaa ggacaacaat tttctcaacg acttcataag cgagcatccg accatacact
    18961 tcaagataga atcggtcatc ttgctccatt tcttcaagat ccgtaaagag ttttttctca
    19021 gcaataccgc tatgggcggt aatcacggaa tgtgtactct ctcctccagt tggaaaagag
    19081 gtgccttgca ggactgtcgc tcctctatct aacaaaagat cattcgtttc atcaaataaa
    19141 ggcaagctaa cattgatttt cggaatatag atggctccga tcatatgttg ttcgtaatat
    19201 tcttttcctg gattttggac atttctaacc gcttgctcaa aaggatcttt gacttgtccc
    19261 attcctggga ttactgatgt atgagcaagc gtctgatttt tcttttcatg cactgctaat
    19321 tgttgctcat gtttttcttc tttatcgcgt tcaagctgct tttgataatt ctcgatcctt
    19381 ctttgatcca aataattgct gagagcatct gctaaaaatg gatatgtaaa aactgcagct
    19441 ccggcaagaa acatcactgc cataaataat tgtaataaaa gactgatttg ggtttgaggt
    19501 ctattaccta ttttcttttt cattttcttc accttcttat ttaaaaaaac tgcagcaacc
    19561 tttataaaac cgattgctgc agcttatttt tgttgcttat acttcagact tcattttaga
    19621 tttacggtac cagctgtacg ctccaatcat caaacttatt ccgattagta agaatgccaa
    19681 gagcccgttc ccaccagtag caggaagtga cccgcgtttc atattcggta ctctttctgg
    19741 ccctggattt tctactccta cgatctgaat ttcttcatta tagcttccat aagagatgat
    19801 aaattcagta aaggctgcct cacctgttgg aagtacataa ccttctggcg ccatggtctc
    19861 tttcatttga taggttccat aatctaaccc ttgaacctca aagtatccat ttccatctgc
    19921 gacaaattct gttgcttgtc cgcttgttgc ccactcaatt ctatctgctc ctgattcata
    19981 aacagctaaa ggcgactccc ctttataaaa tattgcgtat tcagaacggt cttcattcca
    20041 caattcgaat cttgcatctt taagcaattc actgcttgat gcatcatatt tttcaaactt
    20101 tcttccacct gttgtgactt tctctggcgg ctctactcct tcttcataat caaattcatc
    20161 atttcgtccg atttcaataa ccgctgtgtt gttatggaaa tcatccgctt ctagttctgt
    20221 ggaaaccttc aaattatacg tgatcgttaa atctcctcca cgtgcatctg ctaatctacc
    20281 taaagtatct actttggcta ctccattttc ttctgtcaaa atcgtcacga caaacccgtt
    20341 gcttactact tctactatat aatcttgtcc ttttgttaaa atcgtctcgc cggctcgcac
    20401 ttctatttcc tgatcataat aagttagacc aactgtaggc gtatctgtga ttttgtaatt
    20461 tttgataaca gcgcttccgt tttcaaggac agaatcgatg aaataaggaa taggtgctgt
    20521 gatcgtgtaa gaagccgttt ttcctctttc tagatcaata taagaaatcg tttcttgttc
    20581 tccagcttca ttaataatcg ttacttgtct aaggtcgctt tcctctacat tcatctgttt
    20641 atctgcttct ctgatttcgt ttttcggata caaatgcaca tctgtattgt atgtgtcttt
    20701 ccatgtagaa ccatcccaca cgccatccac catatcaggc atcatcactg gcatcataac
    20761 aaccattgga gacgcgattc tggaaatatg agctggcgaa taagtttcta agaaaagata
    20821 gactttatct ctagaagaag gtgcttcttc cgtcacttgg acggtagaga ataccgcttc
    20881 tccagcttca ttcgttgttt gtttgtcaat acttgtcagt cgatatttta aaaaccaact
    20941 ttctgtgtgc cgtttttgaa tccattcaat cgcttcggca gaattaagac cgtcttctcg
    21001 ttccggtgtt aaaggattat ctcgaatcaa atcgtaatat acttccgtta cgtcaaacaa
    21061 atcaaaatcg actcctggaa tattttcttc accaaaatcc gtagaaacca atccgctatt
    21121 cggtcgttct tccggaacag atgagaaacc ttttttgtgt aatgtaatcg tcacttcact
    21181 tggtttttgt gcgacttctt cggctttgac tagttttccg ttcccgaaaa tccctattcc
    21241 cgcagtaacg agtaacagta cactcattcc cgtgacaatc atttttttat tcattttttt
    21301 ctccccgttc tttttttatt aataaaacag cacctaacaa taaaagaatt cctagtaaag
    21361 aaatcaacgt tcttgcttca ttcgtttgcg ggaatacgga ccattttcct gattgacctg
    21421 gattgcttgg accactcggc tctttcggtt tgtccgttgt ttcttttacg gtctcgttat
    21481 aaacacgtgg tgttgcggat tcataggcag agactggaac tttcccggat tctaattcag
    21541 ccatctcctg tccgttaact actacatatt gtggttggcc ttttgcatcc acccaaaatt
    21601 cagggatgat gacctcgatt ctcttacttg cttcatccat ctcgtaacct tccacacctt
    21661 ttaattcttc aaaataatag gtgccagaag gcaagaaacg ttgtcctgtc gtaacaaggc
    21721 cctctttatc cgaaatgaat ttgcttacat ttttgtcatt caaaggatca ttgtctgctg
    21781 gtttgatcca ttgatttttc aagtcattag caggagccat atctaaataa tatttccccc
    21841 cttctatcat ctgatataga gcaaaaacag caccttctaa tggttttcct ttttcagttg
    21901 ttcctctttg acgtccatac ttgaagaagt atggatctct tagataaccg acatttttag
    21961 gatagatatg aatctcttgc agttcctcgg ttgattctgt cgggtgataa attggcaaaa
    22021 tagcagcaat tgggatagct gtctgatcga tatcaacatc caatccaact tctggatcaa
    22081 tcgattcttc gaaaatcaaa taaactgcat cccgatcttg gtttttctta ggtgctttga
    22141 tacgtgcaat cccgtctcct aatccgccaa ccgtatcttt cccagttgtt accgaagtcc
    22201 ctatttggac aagcctttct tctgtgatta gctgacggat attgtttctg ttcgtttcag
    22261 cgatttgctg gacgaattct ttaggagtca tgttttcagc agcttttttt tcatgataat
    22321 aatcggtcat gtcgtaaatg gcaaatgtcg ctccatttag tggcaccgtc tgtgaaatga
    22381 tatctgctgt ttcccctgct tcctcagaga tagccaagcc atcattttca tggtattcaa
    22441 attgatcgtt ataatcgata tctcgaatca tccgtttatg caacacgaat tccacgacat
    22501 cttcccctga ttcttctgcc gacatcgcat gtggaagaag gactgctgca agcggtagta
    22561 aaacaagtaa ttgaagcatc aaacacaaca gctttttcat taccttgctc cctccttttt
    22621 agattgtctg acaaacaaac cataggctgc tcctgcaagc gccatgaaga atgcagcaag
    22681 caggatatag aataatcgtc cggatcctcc tgtagcaggc aacggatttt caggatcgtt
    22741 cccgacacta agctgtaatc tgattcgatt tgtctccaaa agttcatatt ctaactcttg
    22801 ctgtagatca ggcgtctctg cttcttcgtt tggataatac gaaatctcaa cttttagtgt
    22861 acccgcttct tttcctggaa ctacccgatc attttctatg tcaggttctt ctcgataact
    22921 aatttctaaa ataaagtaac ctggaagttt tctatagctg tcaggtgact tcacttcctt
    22981 gatccgatag accccttcca acaagtctga agcattgaat agggaagaat cgtttggatc
    23041 tggtgccaag cctccctcga tgatttcata ctctcctgca ctattttgtt tctcaattga
    23101 aaattctgcg ccttcaagac gtcggctatt catactgtca attttcaaaa gttccaaatc
    23161 gattggcgct agttcatctt ctaaggttac ttgtagtaca ccatcgatga tttcatagcc
    23221 ttccggcaag ggagcagttt cgtcttcgat gaccgtatct tcaatgataa acttaccttc
    23281 ttcattcagt gcaaactgga acacttgatc agatagccga tacccatttg gtgcgacaga
    23341 ttccgagacc tcatattcac caatagacag atgcagaggt tggtcgtaat ttaaatcgac
    23401 atacttttct actcctacgg cacgagaata gaagtatccg atcccaggca aacgtttcga
    23461 ttcttctggt tctaacggat taccagtgta tgctcgatac agcgggaagg aagaatcccc
    23521 cactttcctg atatcgaaac ctgcaccatc taatgtatgg ccttcatggt ctaattttct
    23581 aactcggatc tcccgataat caaacgtatt gtaagcagtg aatgctaccc ataaacgatc
    23641 ctcttcatct gttgtatacg tgagatattg ccaattttct tcacctgttt gcttgagttg
    23701 gatagtccct atagcattat cgtaaagtcg caagatccat gtgtcatttt catcaggttc
    23761 tttgaaacct tctgggttct ggctctcaat gattttgtat tctgcatagt tggtagtttc
    23821 ttcactatcc ttataaacaa atgaatctgg ctctccgatt ggatgaataa ctttctcacc
    23881 atccacgatt acatatttcc cgtcttcatc tactgaatag aacgtgagtc tccctttctc
    23941 ttcctctact tcgttcacac cagaaagccc tttcgctact ggatatccga tttccagtcc
    24001 gttaccatct gtttcataaa gttcaaactc tgcgccattg attggcatat tactgccttc
    24061 aattagttta ttgatattca tgtggattgg cttgaattca tttcgcattt ccagtttgac
    24121 atacaactca tcatactctg tgccttctat gttaggctct tgtacaacag aaagcttgtg
    24181 atattctcct tcataatagg aattcggatc tttaccttcc ggtccgccga ctctcgaacc
    24241 agatgtatat tcatctacaa gctcgtagtg acctaacatc tcatcttcgt tggctgcata
    24301 ttttttgatt tggaattgat acgtctcatc tactaactga taacgtggtg gtccagcgat
    24361 ctctctgatc caaaatatgt cgctgactgc tccagtttca tctcctaaaa tcggcatctt
    24421 cgtttcaaag atcgctattc cgtccgtggt agttttactt gtttcgattg gttcggcttc
    24481 cccactctct ggattttggt catataatgc aaattcgact ccagccaacg gctcgccatt
    24541 ttgacccttc ttgctgactt ggaaattacg gcctttatgt tcgtaacgaa tggaagaaga
    24601 tgggaaatac atccgtccag tagtgatatc attctcataa tcctccaggt tctgaatata
    24661 ggccatattg ttcactgtgc aaaaatttcc gtcttgagct cccgcatcaa gttttacttg
    24721 gtacttgatc ctgaccattt ccccttcacc taaagaaatc ggagaaaatt tataagcttg
    24781 gttttcccgt ccgacatacg ttgtcggagt cgccactact tctggtgggg cttgtccatg
    24841 acgttcttca tcccatattt ctggctcttg gtacttcatg ccgttttctc ctggatctag
    24901 atggtaaaac tgaatatctg ccgatctgcc agctccaaat ggtgagacat taaaaccagt
    24961 ttcatcataa agtgtggctt gctggatcgt tctcttgaag gtagaagaga tatcctccaa
    25021 ggctgtaaca atgtcattct tgttgttcgc attgtaatat cgcggtgtta cgccatcttc
    25081 ttctaaatca gcaatatttt tcaatacatt tcgtccaata gcatctagtc gttgtctccc
    25141 gctaacgttt ccatcgattc ctaaaccaat ggagaagata cttggcgggt tctcttgata
    25201 cttgtttttc agccaatgat gataagcaac tgtgttgatc gcagatgact tttcttgcga
    25261 agtaggactg ccattcgtat tgttattaga agaaccatca ccaacccagt gagtcgcttt
    25321 attatctcct tcttttacct ctccataacg atagtgtaca tttacttcat cttctggacg
    25381 gttaaagtca gatgcatagg taactggatg agtaaaccct gcattagaag tattcccaga
    25441 aaactcctca aaatttctga acaaaacgtc attatcttca gcaatcttat cttccatcac
    25501 agtccagttg ctccaagctc cattagtgct cgtacgataa cttgactgaa tcggtgcata
    25561 actgaaggtc ggtgtcccat ctcccacaac gattaggatt ttttctggat ttctattttc
    25621 tccgccattg tctttataca atgtttcata gccattttta agccctagtg taagcggagt
    25681 tcctccgatt ggtgtacgat ttaatgctgt attctcactt cccgtcaaac gattgatatc
    25741 atttgtcaat ggaaagatgt ccgaactgat ttgctcatgg ttattgatag ctgtactatt
    25801 atggtaaaaa ttcaccatac cgattcgaat atccagactc gggtcagaga gcagatcttt
    25861 actcatttcg tttactgcct caatcaacgc agcattttta gtttgactat tggtcccagc
    25921 ggttaattca ctcatactcg ctgacttatc tagaacaaaa acgatatcga ttggactgat
    25981 ttcctttttc tcgcccccga tgacatctag atagacattg taaagggttg ttgcatcttc
    26041 aggatgtaga tcagatgctg tgctgcttgg cagaacaggt tctacccatt ttttgatgta
    26101 cgccccgtta taatccaagt aactgttttc aaaattccgt tcatttcccc aaagctgaac
    26161 ggtttgagct ggaacgtttc tatcttcttc gcctgcagtt gatccattat tagtagcata
    26221 gtcgtaattt cgccagttcg ctcccccgtt tgtataatca ctatcatcga tcaagttctc
    26281 tccgtcatat ggcgagcctt tgtctccttg atagcgttca ttgctttgtg tccaatttcc
    26341 taacactttt gtatagtcat tcgttgtaaa cttcgggtag cgatgctgtt cgttttcaac
    26401 ttctccgcta ggatagatat attcataggg gtcttgcgta gctgttggcc caagacgctc
    26461 caaaataccg ttgaataact ggcgttgaat gcgctggagt gcttgaccgc tgggtacgat
    26521 tggttcgtcc agcttttcca tctcattttc ttcgctacgt tgaatttcag cggaatcttc
    26581 tgtatcagtt tcattttctt gtaattcttg gttatctatt ctttcatcaa ccaccacttg
    26641 aagaggtagt tacccttcgt tcacatcggg gatcttttct gtttcaaaaa tcaatgtgcc
    26701 ggtttctgct tcttttgaat aaacttttcc gacataccat tcttgaccat cgatcgtctc
    26761 gacttttagg tcttctccat cttcatcata ggaggataga cctgttccac gaacgttttt
    26821 tacggtacca atcccggcgg ctgccgcatc gattgctaaa cgtattctac cttcattggc
    26881 actttccttt ttttcaaaag ccagatgcca ttcaagggtt tcttcttttt caatatactt
    26941 cccttcaatt tttgcatagt cctcatctaa gaatacctca tcctcctttg tttctgttga
    27001 ctcagcagct acatccaggg tcgtcatatg atagactgac tggaaatatg gtccaaatag
    27061 caaactgaca gttactaact gcaaaagctt caattttaac cctttcacat ccttatactc
    27121 ctttcaaaaa tatttgtctt ctttcacaac aatcaacaaa acaatgccca tctaattata
    27181 atttaattta attttaattt taaatcaaat gatatccttt ttagttaaaa aacaccaatt
    27241 atacaacatt tattattaaa attaaattat aaaattttat aacgttctca tttaacaaaa
    27301 cttaagttat taagacaaat gaataaacaa ctacgctttc ctcgaaacaa aaaaataaag
    27361 cacaaatgcg catttacgca ctcatgcttt attcgtacaa ttaattcaga taacggcagc
    27421 gcataggatg ccaataacac ttcctaaaat agctcctcct aaaatgtcag taggataatg
    27481 taaaagtaaa aaaatcctcg aataagcgat caaacaagca aataaaaagg ctaatattcc
    27541 tgcaactgga cttaattcga acaacgcagc tactgataaa aaggctagcg ctgtatgtcc
    27601 tgaaggaaaa gaagaagtct tcggtttact tgtgtaaagg acaagccgac gatttttttc
    27661 ataaggtctt ttccgtcttg tcgttttttt gataaaaagc aaaccaacaa aaaaatagat
    27721 caaactgccg ataagaatgg ctagaccata ttctctagta tcaggtatca agactaaaac
    27781 agcagcaagg agcaaccaaa taaaaccacc attagagata ttactgataa atttcaaaaa
    27841 attgattttt cgactatccg ttttccgttg cttggcgaac ttgttgataa tactatcatc
    27901 gattttagca atcaaacgca acatgttatt cctccttttt aagaaccttt tcttgcgtac
    27961 gatggataaa aagcaggact tgaaaataaa acaagaaact gaaacctaat aaagcaaaat
    28021 agattggtcc tgcaaaccag aatgcgacaa gaaggatcaa cgtgcctgcc aaatagaaaa
    28081 gcgcgctttt gaaatcatta aaaaacaaga aaaatgcagt aatccaagaa gcttcttttt
    28141 gttccagttg aagcaagatt ttgtaactaa agagaagcgc gcttaataga agcaaaaaca
    28201 acgtagtata catcaatgta tagccaattc ccccacccca atagcggaaa atctgataat
    28261 cgatcaatag aagaagaaaa taaacacttg ctaaactatc ttgctttcca taaagagaga
    28321 agttctcacg aaactttttc cagaatagtg aaccgagctt tttctcttca ttttttttgt
    28381 aatgataaat catatacaga actgttcgac ttgcagttcc taatgtgaaa acaggcaaga
    28441 cgcacaggaa ccatagtagc tgtaaatgga taagacgtgg aatccattca atgatttcta
    28501 agaaataatc attggctttt ttaccaatcg atcgattcat catccttttg aacctcctgt
    28561 caaatccatc ccttcaatga aataacgttg tgcaaaaaag aacagcaaaa tcgtcgggat
    28621 caagacaagt gttgctcctg ccatcagata attccattgt gtcgttgctt ggttctgaaa
    28681 aacttgcaag ccaatctgta acgtgtattt ttcttgatct tggatatata acagaggacc
    28741 taagaaatca ttccaagctg cgttgaagga attgatcgca atggtaatca aggcaggttt
    28801 cgtcaatgga agcatcaaat gactccaaat atacaaatga ttcgctccgt cgatttcagc
    28861 agcttcgatc aattcattat tgatcgataa gtaaaattga cgcatcagaa atatattgaa
    28921 cgcattgccg aagaacgatg gaacgatcag gggcaaataa gtacctaccc agccgatctt
    28981 ggagaataat acatattgag ggatcatcgt tacaaacccc gggatcatca tcgtagaaag
    29041 aaccaaagca aacatcagct ttttcccagg aaaatcaagc ttcgcaaatc cataagcaat
    29101 aaaagaattt gaaaggacat taccgatcac tactagcaca gtgatgaata atgtatttct
    29161 tgcatagcgc caaaaaggaa aggcggcaat cgtatccaga tagttttccc atacgatttt
    29221 ttctgggaaa aaggtcggag gataacgaac gatttcttcc attggtttca atgaagtaaa
    29281 caccatccaa agcaatggaa tgatcaaaat gattcctatt actgtcatga ggacataact
    29341 tagtattttt ttgtttgccg attcacactg gtctttttga aataatccat catttgccgt
    29401 cacctccaga ataatagacc cacttaggtg caagcttcaa attgacaaac gtcagaacca
    29461 acacgatcag aaacaggatc attgacatag ccatcgcata accagctacg aacgccttgt
    29521 tccacatatg cagattataa aaaagcaaag aatttgcagg tccgcctgtt ccatttttcg
    29581 tcatgacata agcttcttga aaaatttgga aagaaccgat cgtagaggtg atcacatcgt
    29641 aaaaaataat aggagtgatt aatggcaaag taatactttt gaactttccc caaacgcctg
    29701 ctccatcgat ttctgctgat tcatataaag atctaggaac attttgtaat gtagctaagt
    29761 aaagtagcat tgctcctcca gaactccata ttttcatcaa aatcaacgca ggtttcgtcc
    29821 attgtggatc aaacagccaa gctggtccag ggatatggaa ccagcccaga aatgtgttga
    29881 tcaatcctgc agatggagaa agcagctgca tccataagat gtagactgct actcctgata
    29941 agactgccgg taaatagaaa gctgtacgga atacactgat tcctttgatt ttttgattga
    30001 gtactgtggc taaaaacaca ctgaaaatcg tcgtcagcgg tacattgaag atgacgaaat
    30061 aaacggtgtt gtataacgat ttccaaaata aatcatcgtg aacgaacatt cttttgaaat
    30121 ttgctagacc aatgaaattc atcttggatg tcaaattata atcggtgaaa ctaccaataa
    30181 ctgaaaaaag cataggccct agcataaata ccaagaaccc gataataaaa ggcgagataa
    30241 ataaataggc ccatcttgct tcttttttct ttcggataga taaacgcttc aaattttctt
    30301 gcctcctctg tacctagaca gtcaaaaatg gattattgat tttgcttgac taagttttct
    30361 actgcttttt gtgcatctgc caatccttct tttggtgatt ttgttcctaa aagaatctgg
    30421 tcaatctgtt cattcactaa tgtcgtgtaa tccggagcat ctaaaggaac tggtgtgatc
    30481 accgtatttt taaagttttc gtccgccatt tgatagatca tttttccttt atccgttagg
    30541 ttgtcattat tcactaaatt ctcattggct gtcttgctcg ccatgatatc aaaacttttt
    30601 tcgccgaatt tttcttgtac ttctggagaa gaaagatatt tgatgaattc ataagaggcc
    30661 tcaggatctt ttgctccgta tggtacttcc aagacgaatc cgccacccca cgaccaatgg
    30721 cctgaacctt cttctttttc tgggagctgc atcacgccaa aatcaaaatc atccggtgca
    30781 ttttccatca aactagagta ataattgata ttttgggcac gcatggctac taatccggaa
    30841 ataaatggat cagatacacc agacccaaat tcggcttcta atttattgat cgtatttttc
    30901 ccataataat cttgccagtc ttggatccac tccaaggctt ccactttatt tttagtatca
    30961 atcttgactt tttcatcttt gtcaaaccaa ctagtcccgt tatctgcgtt tagcgcccat
    31021 acatcagccc ctaaattcca taatggataa aaaccgatgc gtgtaaattc ttttccttct
    31081 tttttatcta gtttacgtgc tgtttcttct aattcatccc aagttgtcgg tagatcttgt
    31141 tcactgattc cagcttcttt aaatatcttt ttattataaa aaatgacttg tgtatctgta
    31201 ttgaatggga tcgcataagg atcaccttca tattctactg tatcccaaag ctgcggataa
    31261 aaatccttag aagtgtcttt ttctacatat ttggagagat tagttgcttg ctgtgcttct
    31321 gctctttggg caacggaatt tatgtcctgt acaataacat cgggtgcatt tccagctgtt
    31381 attgcagata aagatttagt ccagatgtca ccccatggct gatacttata atttacatgg
    31441 atctcgtttt gtgattgatt gaaatcctca atgatttctt cgatagcttc ttttcgtgca
    31501 ccggatcccc aaaaggacca gaaatcaata ttttttcttc catcacttgt tttttcagaa
    31561 gaatttgctg cacttgaact ggcatcgctt gcattacttg atccgcatcc tcctaataaa
    31621 aacaatgctg aacttgccag caaccctgta aacaataatt ttttcatatt ttacctccaa
    31681 attttaatgt aaccgatgcc ggttttaata taacgatatc attttgttct gaaaataaca
    31741 atttataagg tatgattcta aaaaaattat taatgatacc aatactttat ataattcgcg
    31801 agcgctttct ttgaattttt taatctttcg tagcagaatg agaatgtatt aaaaatagat
    31861 taggaggaat tttgatgttt agacaccaga aagaattgca gtttgaagca aaaccagatc
    31921 gtccgaatcc attaatcgcg aaatatctgc aggagctgat cggcggccaa tatggcgaga
    31981 tgagtgtagc tatgcagtac ctgttccaag gctggagctg ccgaggagaa gaaaaatata
    32041 aagatatgct gatggacatt gcaacagaag aaatcggcca cgtggaaatg ttggcgacaa
    32101 tggttgctcg tttattagag ggtgcgcctg ttgaagatca agaagcagcg atgcaaaaag
    32161 atccaacaat cggtgccatt atctctggaa tgaatccaca gcacgcgatc gtagctggct
    32221 taggacctcg tcctgctgac agcgtgggca atccatggag cggtgcctat atcattgcga
    32281 gtggcaactt gttagcagac tttagagcta atttaaatgc cgaatcacaa ggaagacttc
    32341 aagtagcacg tatttacgaa atgatcgatg atcgtggcgt aaaagatatg ctgtctgttc
    32401 tccttgcaag agatagctat catcaaaatc tatgggaatg tgcagtgaaa gaattagaag
    32461 aaaaagaagg ttcaatctta gtcccaagta ctttcccgcg tgacaaagaa cgaaaagaca
    32521 ttgcttatga cttctataac ttctcagagg gagaccaaag tagtgaaggt tcttgggcta
    32581 gtggcaaagc actggatggc gaaggcgaat atcaatggtt gaaagaacct aagatcgaag
    32641 gcgctgcacc aaaattagaa ccagtaacac caaaaatgta tgggacacct ccattcaaga
    32701 aataaatatc tacccgtaga aacacccgtt ttttgttcca cacgctttgt gagcaaaact
    32761 gactaaagtc attaatcata accacccttc aaaagggtgg ttttctctag agctataagc
    32821 tcaaatcacc ggccagcgcc taaagacgct ggctttcata ttttatgttc aagccatatt
    32881 gcctttgcca gttttgccca cctcttaaaa ggtttatgta ctactcctta gcccttaaaa
    32941 ggatcgtctt actctcgtac actcagctta tctaacgcac tatcatgttt ttcttgttct
    33001 tgaatgtact ttttgatggt cgcttcattt tgtcctactt ttgtcacata gtatccttcc
    33061 acccaaaagt gtcgataccc aaatttatat tttagatttg cacaatctct tgatgatctc
    33121 ctgaatattg gctcgatatt gattataaat tatttttctt ctatactttg gtgtgaatac
    33181 aatgtggtat ttacacatct actttgtacg ggctaaacta tttcccttta ttgctccacc
    33241 cgcatagcaa gtggttttgt atttcaatcg ctcggcgcgc tcaattaggt ctaaagacaa
    33301 taaatctaaa aacccgctgc ttcactgaca gaaacaacgg gttttcagaa aaaaatgaaa
    33361 tgaaaaagat ctcttacggc aatctatttt atttttttga ttttttataa atggaaaatg
    33421 cttcaagaag tccaagaaat aaagccgtat aaaaacaaga acctatgaaa tctttattta
    33481 ttagatattc aacagaaatc ccgataacac tagccaacaa tatatttatc agaagtgtaa
    33541 aataaggatg ctttttatag aatagaacta gtgttgtttt catagactct cctttcttca
    33601 tatttccaat taatcacaaa ttcacggcat tactagaaaa attaaagggg cgcagaagtg
    33661 gaaaaatact cttcgacttt ccctacaaac caggccatct tgtgtttaat aactatacca
    33721 aatctaaggt acctctaaat ctaaattcca tttgtggcgg tgacctccaa tttttaactc
    33781 ttctatctcc catccagtat acataacctt gatacttcga ccacttatat atcgaacaca
    33841 caaataccta tccattgcag gagtactacc taacttagtt gctacttgca tctaaataac
    33901 agctgaaaag ataggactta ctcttagtaa agtatctgaa ctattaattt ttaaactatc
    33961 atttttatcc tcaactacat gcacatctgt tgcaacttca ctttctgtct catccagata
    34021 aatgattaag gaatcgggaa ttgcaatatc ttcagctgac gctggaatag ttgagctaaa
    34081 ttagtcatca tatctttatt ataaaataac caacagcaaa aaatacaatg aaaaacaaac
    34141 ttggaactaa tgtatcatta ataaatgttg aaaaattcag caactcatta ctgtatgatt
    34201 ttagcagccc aaccaacata taccctataa aagctaataa gatggttagg aatcctttag
    34261 aatttttact cattcataga cacttcctta aataactttt attatagaag gtattgtaaa
    34321 taataatatt gacaaaaagt gactcaaaat aaaaaaaacc ttacattata ctggaatgaa
    34381 ctgtattgat agtgtaccta aaagctctac tgacataaga tcgtgtaatc ggtaaagtaa
    34441 ttttattaat tatacgggat gtaatcaatt agagaataaa ctaatcataa aaggtacttt
    34501 tacattcata attgtcgctt tgagattcta ctttggttca ctatctgacc caattgcaca
    34561 ttttcgatca ttacaagtat tggtgtcgtt agaacaacta aataaaaact agcggtagat
    34621 ttttcagaat ctatgctaat ttctgtatgg atgttccagt gatggcaaat ttctcttttc
    34681 attgtttttc ttgtcgcatg atatgccttt ttgtgttatt cagttaaact atagaaattc
    34741 tttcctagac agatcttgat cccaaatttt acgtttttga gcatcgatat agtttaaaat
    34801 gacattactc atatctaaag agtttagatt ttttaggact aaaactgtca gttgttcttt
    34861 ttcttctttc tgttaaagta ttgtcgcgac ttttcgtata cgttaagata tgtcgtgaaa
    34921 aaacaagttt tgtgacacaa aaaaacgaat gacttgagga aatcacctca atcattcgtt
    34981 taaaatgcta tatattcttt agtttaagat acggaaatta atgccatcga ccacactagt
    35041 agaatgaacg acatttactt ggcctttttt taatttcgtt atgtttagca tataaaaata
    35101 ttatagagtt tacttacaat gcttaaaaca tatactgtat aatctgatca attttagcca
    35161 tgtcttgcaa tggtaagttt tctatttttt tgagttttcg ttccttaaaa tcaagagatt
    35221 ttaattgtgt aataattact tgtcctttta tatctagctc ttcaggtaat gagtaacgtg
    35281 tcggtaaatt ctttatagtg gaagtaattg gacatatgac cgaaaacatt gttttacggt
    35341 taaattcata acgagagacg actagtcctg gtcgtctttt ttgaatttct tttcctacgg
    35401 agggatcaaa atcaatccat acaatatcac cttttttagg aatataaatt ctttcttctg
    35461 acactataaa atttctctcc cttcaggagt taaatcttcc cattcgtctt tctcataata
    35521 ctcggcctct tccccaccac taaatggatc ttcaattttt ggaactaacg taattgttcc
    35581 atcatcagaa tacacaacga tatattcttg gttttctgaa ggtttctttc cgttatcaga
    35641 aggtaaagtt accactacag aacttccttg taatctagat tttgtaacaa gcattatcat
    35701 cactccctta ataaaagtat actatataac actaagtaac gcaaaattcc cctttgtaaa
    35761 ctatctagaa aattgttttg tttaaagtat atcttattgg atataaatag aaataaattg
    35821 tagccagttc attttttctt taactaaaaa aataatccaa gaaacattga acctatggat
    35881 ccaaaagcta cccaaatact atagctaacc ccccgctacc ttcaattttg cagataaaac
    35941 gctttgggag aaaatttcaa agacaacagg ccatcctatc atgcccgatt ataaacaaaa
    36001 agctggctat tccttttgct ctgacaaatt tcaattggga aagttcacga aactagcagg
    36061 tgaagaagtt tcaactgttc ggatcaaaga atgcccgctt caaatagaaa cattggttca
    36121 acgaatttca actagacaag actttgctat tgtagaacgt gagatcgtag ctatttttgt
    36181 agaagaaggg attttacatg atccaactca tatcaatgtg gataaatggc aacctcttat
    36241 ctataaattc agagaatata caactgccaa ccagtcgtta actttgaatt ttagattcca
    36301 agaattcaaa gagtcataat gataaacatc gttaggtata aataaaaaag actcgcagca
    36361 cgagtaaaaa acaaatagaa gctatacatt agaaaggtcg actgtgaccc tatagatgca
    36421 gtatatgcag cttatgagca tttcttctgt tctctttgtt tttgggatct gtgctgaagt
    36481 ctttttcgtt ttttgccgct ctttctttga aaaatcgatt atgttatacc ttctccatta
    36541 ctaattcagg catctgctga gtaatgattt ttcgcgcaaa agaaatatct gttacccaag
    36601 gttcgatttg ttcttcagtc aagacaagcg gcattcggtc atggattggt gcgactgtgc
    36661 ggttaggttc agtagtcatt atgattgatt ctgccatttt ttcatcctga tggctacgat
    36721 aaaaaccgcc aatatacact attttttcct tatttgaaaa cataaatttg tctttttctt
    36781 cattccactc attgggaaaa cacaacgatt ttgcaaaaat ggttgatgaa aggtcttttt
    36841 ttcttctact gtctctgcac gggcattaat catcaattgt ccttttttaa atccggtaaa
    36901 tccccacttc atgatttccg gagtgaggat gttttcttcc tcttttctta acgtcacaac
    36961 aagatttgac ggaaaaactt ctccagctgc taattctgct gcctgcttcg gttgtttcgt
    37021 ctgggcttct cgataataat tctgaaggag ctctgactct agatcaaaaa aataacgacc
    37081 acacatccta atccctccca atcttttttt ctatcataca ctgcaacaag aagttcgcac
    37141 caacaaaacg ctttcaattt ttgtagaact aaaaaagttg tgacaagtga caaactctcc
    37201 agtgaatggt attctcctgc caactcctcg gtcacaagtc acaatattca acaaacatga
    37261 gaagctgctt tttgaaattg ttccttgtga ctcggagtga aacggcaggc ttacgacctc
    37321 tgggtaaacg gtgttcaaaa gccagtttct cggtattaag ccaaatttat gcaaaaatgt
    37381 agaaagctat tttcacaaaa tttttcttaa tactcgaaac taagcgactt tttcacaacc
    37441 tcttccttaa acggtgttca aaagcttgca tctgcggtaa taagcccaac caaacgaaaa
    37501 atatgagcag ctatttttat ttggctgttc ttattacttg atgcagggca gctttttcac
    37561 aacctctcca ctaaacggtg ttcaatcagc taaccttcgg tattagctca aaaaacggca
    37621 aaatatgagg aactattttg ccgtttgttt ctctaatact caggtcaaag cgctgatttc
    37681 acaacctcta atacacggtg ttccagaagt agcttcttcg aaaaataagc cgaaatttca
    37741 caaaaatttg agaagcaatt ttcgtaaatt ccttcttatt tcttgaagct gaccacttct
    37801 gtcacaacct ctaattatta aagaaccttt tgcgaagtta acaatctttc tttgatcaat
    37861 tgaaaattct gcctaagtag tgatagatcc tgtgtgactt tcaacaataa gatacttccc
    37921 tggatttcag caatcaacgc tttggcttga cggtctgctt cttcatcgga cagtttttct
    37981 tcagaaagtg ccaggatatt ttgtttcgta tacttgaccc attgattgac taattctagt
    38041 agcaacagac ggtattcttc atccactgta ctcaactcaa taatcaaatt acctacagga
    38101 cagccatgat aagtgatctg tgtctcatga tcagcgaaaa tccagtccaa catttcttct
    38161 aatgcttctt ctggctgttt tccagcattt aagatgtctt cgaacaattc tgtctgccat
    38221 acgtccatat gcgcatggat caccgctaga caaacttctt tttttgaaga aaagtaataa
    38281 taaaattgac cttttcctgt atcagaagct gctagaatat ctcggattga cgtttcatga
    38341 tagccttttt tataaataag atctttggtc gcttccaaga tcttttcctt tgttttcaat
    38401 gatattctcc tttttcattt ctcatagtcc tatattatac agtaaattca tcattttttc
    38461 ttcttaatcg tttaaaaaag actgtgccaa attatctgac acagccctca ctataaaact
    38521 gttctcatat agctagatgt tcattgattc aagaactgcg aggacaaaag caattcctat
    38581 cttatgatag ttgctctaat acttcctctg ttgtcatcac ttgatctgca ataaagccaa
    38641 agttcgtcaa cgctgcatcc attgcttctt ggccaggagc accaattgca tctgtcgcta
    38701 ccacaacatt gaatccactc tctaccaatt cacgcatatg ggaatcgcta cacaagtttc
    38761 cgttcattcc accaagaatt actgtgtcga ttccattttt tctcaattgg agcgccaaat
    38821 cattgctttc tggtccaaag attttatgag gagagctgat gatcgtattt tcatccaaat
    38881 aaggtttcaa ttcttcgata aaatcggctc ctgaaccttc ttccactgat tcatattgac
    38941 tttttctagc aaacatctgc tgctcaagca tcatatgttc tcctgcaccg ccaaattgcc
    39001 atttatggtc atgtgggtaa aaataatgag gagaaataaa gagtttgtat cctttttctt
    39061 ttgcttgttt taccatttca atcatatttt cgatcgtatt gtatttttct aagatatctt
    39121 ttgtcaaacc aaagccaccg cctgctggtt tcaagaactc gacttgcggg tcagtgagaa
    39181 ctactgctgt atttttatta ttgaacatgg tggattctcc attcgttatt tattttaata
    39241 catcatttag agcttcactc attgtcggat gagaatagat ttgatctctc aataacgtat
    39301 aaggaagttt tccattcata gctagcgaaa tcaagttgat gacttcatga gaatcttccg
    39361 catagatact tgcccctaga atcaagtcag tttcagggtc gactaaaact ttgaatacac
    39421 ctttaggatc ttctaatact tgtgctttag ggacaccgct tgtcatatac ttgaataatt
    39481 tgtaattgac gccttgtgct ttggcttgtt tttctgttaa acctacattg gataaagtcg
    39541 gagtgataaa tacactgtaa ggcacagctt tccggttatt cgttgttcgt ttattctcgc
    39601 ccttcaactg atccataatg attcgataat catctagaga gatataagtg aactgcaatc
    39661 cgcctttgac gtctccaatc gcccaaatgt tgtctgcatc tgtacgaagg tattcatcca
    39721 cagcgattgc tccgcgatct gttagtttaa catctgtatt ttctaatcca agtgatgctg
    39781 tacttggttt tcttccagtt gcagccaaaa cttttgacgc ttggattgtt acttcttggc
    39841 catcttctgt aaaggtgacg gcagctgttg attcttggtc tgctacttga tctacagata
    39901 cacctagatg gaattcgatt cccgcatttg tcatgtcttc taaaatcatt tgcgcgatat
    39961 cttcatcttc acgtggaaga aattcagaat gggcatcaag aacgacaact ttagatccgt
    40021 attcattgaa cattgatgca aattccaagc caatatatcc agccccgatg atcactaatt
    40081 tttccggtaa ttgttcctga tccatcgctt gcgtagaatc aatcaagtag cgacttgtat
    40141 tcaatccttt gattggtaaa atgattggtt cagaaccagt attgatgaaa atccgttcgc
    40201 cttcaacaat cactttttca ccattattcg tcacttcgat ttgatggtta gaaagaaaac
    40261 gtgctgtacc gtccatcact gtcccagttg cctcatcgct gatcatatga taatttttgg
    40321 cgcgaagcat gcccgtcaat ttttctttcc gagcaacagc ctctgtaaag tcgattcctc
    40381 tttctccatt gaaaatcaat gatttagaag gaatacagcc gatgttgata catgttccgc
    40441 catacatacg tgttgacttt tcaacgacta aaaccgattc accttttgaa gctaacgcct
    40501 tcgctaaagt cttaccgccc tttccaaaac cgatcacaat attttgatat ttttccatca
    40561 tttttccctc gcttcttttt tacctaccga ttggtacaaa aatatgataa ccgataattg
    40621 tctattctcc aaatcatctg ctttatttgt caaaaaaaac cagacaaaaa gcggtccttt
    40681 cacgttttta gtctggttcg atttccttta ttcttctaaa caatcgttac ttctacatcg
    40741 atatttcctc tagttgcttt ggagtaaggg cagaattcat gcgcatcttc tgcaattttt
    40801 tgggcttctt cttcgctgat gccatcgata tgcacttcta atactacacc gatctgatag
    40861 ccgccatcat ctaaattata aagagagaca cgtgctttta ctgtggactc tgctgtcatt
    40921 cctgcttctt tgatcatatg ttgtaccgcc ccattgaaac aagaagcata acctgctgca
    40981 aataattgtt ctggatttgt tccttctgca tggattcctg gaggagtgat tttcatatgc
    41041 atcgagccat ttggtgcctc gacttctcca ttgcgcccgc catggttgat cattgctgtt
    41101 tcgtatgctt ttttcattgt actgctcctt tcgattgacc atttgctact tggctataat
    41161 tatagtgtat gacaagtaag gcgctttcta caaaaattct gcttattcga ataccagaat
    41221 gccgtcttct actatttttc caaaaaacaa aaaaatacta ctcgtgaaca acagcgtcat
    41281 atttgttcca aaataaatag caatcttttc tacataatct tttatatgat tgattttaag
    41341 atacatatat accagaaagt tgaccccata aaccaatact gttaaaaaaa taaccatatt
    41401 cgttaccatt ttttcctcct tttgctggtc tccctaccag cactcgattt aaccatacca
    41461 ctttttttgc cgtccaagca actagccttt caaaaagact ggtttattct gctgttaatg
    41521 attcaagatc agaaaaatgt ccgaataatt ttgctaattt tactaacgcc aacttgttct
    41581 ttccgaattc atcattttct atctgtaata ctagtaacgg ctcatgtaag cttaaacgga
    41641 tcaaaaacca gccgtttccg tatggctctt ctagatcata tcgaatacct tcttcatttt
    41701 ccgggtcgaa gttcatccct ttttcttctt ccaacagtcg cttcatttct tctaatatct
    41761 tgtttccttg ttcgcgtggt tcatcgctga acaattttaa tcggatttct tgtacttcta
    41821 cgggctgttt caactctttg atttgttcat ctaatgtgat accttttctt tttaattctg
    41881 gcaaaagcat caggatcttt gcgatgacat atgcaccatc atccagaaaa tagttttcct
    41941 tgaatgcagc gtgtccgctt gtttcgatgg ctagctgtgt atctttccca agacggttaa
    42001 gttctaatgc tttattgatt acatttcgat agccggaaat ataacgaact tggatgcctc
    42061 ctttttcttc aatgaatctt tgtagatgag aagaagtagg ggaattcgtc acgattcttg
    42121 ttcctggatg ctcttttaat acgattgtac ttaatactgc gatcaaatta tttcgattga
    42181 tcactgttcc agaagcactg acaactgcag aacgatccac atctgtatcg aaaatgatcc
    42241 caagatctgc ttcatttgct aaaacagcct gcttgatact ttccatcgct tctttattat
    42301 caggatttgg gatatgatta ggaaatcggc catctggttc caaaaattgg gaacctgttg
    42361 aatccgcacc taagctattc aatacttttt cagcaaagaa tccaccagca ccatttccgg
    42421 catcaacaat gattttccaa ccatttagtg gtttgctttc tagtgttcca atcccctttt
    42481 taatttttgt gactaaatct tgcgcataag gtgtcaaaag gtctgctttt tctacgcttc
    42541 cagtttgttc gctttttatt ttttgctgct gtgataggat aaaagcaata tcttcttttt
    42601 ctgctcctcc ttctgaggta aagaatttta ttccattata ataataggga agatggctag
    42661 cagtcagcat aaccgcagca tcgcacgaga actgttcaaa ttgagtggac ataaacatag
    42721 caggcgtagt agctaattcg aaatcgatga catgtatccc ttgttctttc agactttgga
    42781 tcaacgcctc tttcagtgct ggtccgctta tcctactgtc atgaccaatc ccaatcgtcc
    42841 attttttatt tggatcggtt gatttcttct ttttctttat ccagtttgct agtccccagc
    42901 cgatcttttt taccatgtct gtcgtcaagt ttacttcata tccttcaact ggtaatgcga
    42961 ttcctcgaat atccgatcca ttttgcagcg ctttcatatc tttcatataa aagtcctcct
    43021 catttattcc ctcatttttt ccagcttttc tgcaaatcgc tgtgcttctt cttctgagcg
    43081 gcaaataata atgaatgtat ctacaccggc catcgttccg acaacttcag ggtaagccac
    43141 ttcatctagc caattcgtta ccacatcggc accatttcgt tcagtcaata cgataaccat
    43201 gaactgaaca gactggatac gcaaaacctc gcgtctaatt gctgtacgca aacgttcttc
    43261 atttaaagaa acagatggct ggttaaataa tgtatagcgt actattttgt tttcattttg
    43321 actttttact aacttcattt ctcgaatgtc tcgagaaatc gttgcttgag tcacatcggc
    43381 gcctgcttca tgcagccgcg caagcagctc ttcctgtgtc ccaataggtt gttctgtaat
    43441 gatctggcgg atcagtgctt gtcgctgttt ctttttcata ttagacacct ctcaatgttg
    43501 attatagcaa aagataagta atatttcttc atattttggt attttttact tttatttttt
    43561 gttttcattc aggttgctaa cctttttcta ttttaacacg caaaatcgtc ttcatttttt
    43621 caggtgctga ttttcttgga tcgctgatgt aaatctcttt gtgttcttta gaagctcttt
    43681 catagccttc ttttgcgatg aatgcttcta atttctcaaa cgttgctggt tcttcggcat
    43741 agggcccgac gtgtaagatt tgggcacaaa gaccttcttc catctttttg aatactactt
    43801 gttctttcaa gtcttccgga agtttgctag aacgctgaat ggcttcttgt gctatcgctt
    43861 ctgtaacaaa gtcaggctgt cggatcatca attgataaga aaaatgttct tttttcatca
    43921 ctggttcatg caaatacttt tcttgcagtc cccattgtcc ttccagtgga tagacagtat
    43981 acatctgata atcaggaatc agccaatttt ttttaggcga catgcgtatt gcatagctga
    44041 ctgcatatag acaggctact cttcgtttaa agtcttcctg attcgggtcg ccgatccctc
    44101 tgatgctaaa gaatgatttt ttaggaacct ctagtatttg cgggcttttt ttcatactat
    44161 agctcttgtc tttacgccat tcaatttttt ccatttttct tcctccgcga aattccattt
    44221 agttatttat tatcatacct ctttttgagt gacttggcta atcgtgttga cactattttt
    44281 cagtttgtgc tagaataagt gaagtaaata aatcgtacag ataacacgtt tcggcgtgtc
    44341 gagagagagg cggtttctat ttttataata gaaatcactc tcttttttta cgaaattttt
    44401 tagaggtgat gtaaatgaca aaacaaaaac agctgctttt agtacctgca gtaattgcaa
    44461 cagggatgat gtcttttgcg ggcgtattga tcgagacggc catgaatgta actttcccaa
    44521 ctcttatcag acagtttgat ttaacgactg cacaagtcca atgggtaaca acgatttatc
    44581 ttttgatgat ttcgatcatt gttccgctgt ctacttattt gaatcgcaat tttagtctca
    44641 aaaaactctt tttagcttca aatctgcttt tcttggcagg tataatgatc gatttcttct
    44701 ctcctacctt catggtccta ttgtttggtc gattgctcca aggtgcagcg acaggtatcg
    44761 ctcttccgtt gatgttccat attatcttga catttgcccc cctcaatcga cgaggcgcga
    44821 tgatgggtgt cggtactttg acaacggcca ttgctccagc aattggcccc acttatggag
    44881 gcattatgac ttcacatttt acatggaatc atatcttcct gtttcttgtg cccgttttgt
    44941 ttctttcttt gattatcggc tggtttgcta ttcccgagat ggcagtacaa aaaagtggtt
    45001 atttggattg gataagcgtt ttaggaattt gtcttttgtt tagtggaagt ctaacatttt
    45061 tgagtacgtt gggaacagtt tccagctgga ttgctttaat catcggcggt attggctggt
    45121 tcctttttta ctatcgaagt aaaaaagtgg agcatccact gatccgactg tctattcttt
    45181 caaataaaac attccgcttg tttttgattg gcttcttagt ttatcagttt ttattacttg
    45241 gtgtatcttt tgtcttgccg aatttccttc agatcgttca aggaagtagt ccttttgtcg
    45301 ctggattagc gatgcttccc ggcgcagcgg ttggtgcttt gctttctcct ttttccggga
    45361 aaatgctgga tcaatatggt ccgaagaagc caatttttgc tgggctgatt ctttctttga
    45421 ttggttggct agcattattc ctactcatag gacacgcttc agtgggtgta ttgattgctt
    45481 gtcatgtgtt ttatatgatc ggtatcggat tatcttacag caatatgatg accaccggaa
    45541 tgaatgcact gaatgaagaa ctacaaggag acgggaacgc aatgttcaat accttgcagc
    45601 agttttctgg cgctgtggct acttcattag tagcggtcat tatcaattac gtccagcatc
    45661 atacttccca taactatgaa gtgtctacta cattaggatc aaaagcagca ttaggcgtct
    45721 tgttgctgtt gcttctcgta agctttgctc gattcgccta ttatctgttc tttgctaaaa
    45781 aagcgtagat tccatatacg gcaggtgttg catctgccgt ttttttgtgt gaaaatggtt
    45841 gtttgtaaaa ggaggctttt ttatggaaaa aattgccatt atcggtggcg ggatcattgg
    45901 tatgacccta gccagttact tagatacatc aaaattcaat gttgctttat ttgatgaagg
    45961 gacaggacag gcaactaaag ctagcgctgg gattatctcc ccttggttgt cgaaacgcag
    46021 aaacaaacaa tggtatcgtc tggctaaaga cggcgctgct tttttcccta aacttataaa
    46081 agatttccaa cttgatcaaa cgatttacgc acaatcaggg acacttttgc ttcgacctga
    46141 aaaagattta gctgaattgg ctgttcttgc cgagaaacga aaagaagaag cgccagaaat
    46201 tggaaacatc gaatggcttt cacctgaaca gacatctcaa gcacttccgt tattgaaacc
    46261 agcagtttca ctgcgtatca gtggtggtgg tcgtctggat ggaaaagcat atttagaaca
    46321 tcttggtcag cgtttagcac aaaaacaaat ggagcagatc caggcaaaag tcactttgca
    46381 taagaagagc gattcttggc tcatcaaggg accgtttgga gaatacacag ctgatcgtgt
    46441 aattttgaca cctggcccgg cacttaagcc tttattacaa gaattaggct atgctgcaga
    46501 tatacgtccg caaaaagggc agctcttagc atttcagaca tcttataaga tgagtcaaga
    46561 ctggcctgtt gctatgcttg acggagaagc tgatttcatt cctttcatgg atggaaagat
    46621 ccttttaggt gctacccatg aaaacgatca aggctgggat ttggctccta ctagcgaagc
    46681 ttataaggga ttgactaaga gtacagaaca gttcttgact gatccagatc agataaaaaa
    46741 ctggccatac gagttccgtg taggtacccg tgcttatacg tcagattttt ccccattttt
    46801 cggcgtactg ccagatgatc caagcttact ggctgctagc ggtctaggct cttctggctt
    46861 gaccacaggt ccttatatcg gctatctatt agccaacttc ttaaatactg gtcattggcc
    46921 tacggaagat tatcaaaagg acatctccac ctatattacg aaaaatccat catagaaaaa
    46981 cagctttttc aagtaaggat cccgagcgat attgcgcatg gattacttct tgaaaaagct
    47041 gttattttag ttcaatttct gaatcaaatt ctccaaactt tcttttgctt catctggcaa
    47101 gagatctttt cctatctgag cttcaatgaa tcgtaaacga atatcaagtc gttgtttcac
    47161 cagattttta taggacgtat cctcaaaaga aacaggaaaa tctggtatag gtaaatagtg
    47221 gatgtcttca aatggaccaa acgacttgaa ttctgccgtt tgttgcacga ttctttcaac
    47281 gattgacaat gtcgtttcag gtttgatttt tttatcatcg aaatatccag tattcaggac
    47341 atagcaggct gtttgctgtt tcaaaaacaa ctctcgaaaa gcttgatagt cttccctaag
    47401 aggatagaca cggaaaggat tagcaaatgg ttcaatgact agctcatcta gctgtctttt
    47461 tgtagtgata ttttccgcgt ctgatcgttt tgttgctaat gttgcaccaa aagacgctgc
    47521 taaaactggg tcattgatct tgataattgg cggaagcgaa tcatctttca tgatccaaaa
    47581 aacagcatcg atcttttcgc taagatgatc gactcggtcg ggtgtcgcat aacgtgattt
    47641 gactgtccgc ccatttccgt ttcgtatatc tcctgttact aggacttttt ctcctttact
    47701 tgtacatgtc acgcccacat tctgacaagt aaggaaagaa gaaatggccg gatcatcaga
    47761 cggatagtct tgtgttttat caaagtaaga aggttccaag gcagtagcaa aaccattttt
    47821 tcgagaaata acgaaagcat cgtcatgcaa gatcgaaaca gagtgacctt ccgtatgttt
    47881 tgctaaggta atcgttgatt ttccagaacc ggacaaccca aatacagcca tcgtataggt
    47941 ctggtcatta ctagcatatt gtttcatccc accgtggcag gcaataaagc cattgcgatt
    48001 tcccaatgcc caagcaagcg tcaaagtcgc tttttttaat tctccaaagt aacgtaatcc
    48061 tagcacagcc gctgtattat ggagagcatc aaacaaaatg agtccatttg gaaatgtttc
    48121 atgtgtccat tcgggatcac aaaagatata aagatctccc tcatcaaagg aaacagactt
    48181 ttgataagtc tctaagatct tcgaattcgc tggctgaaaa ttcagcaaat aagaatacaa
    48241 attgttctca aatccttctg gaatcagcaa atgactttgc acagaaaatt cttcagatag
    48301 gccaacgatt acttttgtat ggtaaaactg gcgcttgcga ctttgataca cagcttctct
    48361 taaaattttc tcgtatttgc tttgttcctt gtctaagtcc tcaaagatcc gccgagcact
    48421 tgctgttctt cccacaatgc ttccatcatt gaatactagt gtcctaacat cagctggtaa
    48481 atctagttct tcagcatgtg agattgttaa atctgtgatg atcgttcctg gactcccttt
    48541 tgctagttga taagctgtct tcctatcaaa aacttcatga acattattac cgtaaaatgt
    48601 cgtttctaca atcgatcgaa tactggataa cagtggattt ccacttgtga tttcgtttaa
    48661 ttcgagactc tcttttgtac tcatggctcc tcctcattcc ctaaacaaaa aaacgttttc
    48721 tttattatac attattcgag tttttatttg tactgctgcg ctgtgggaag caaacgagtt
    48781 atttttcaca caaaaaaacc gagaacttga ataaacaagt ttctcggttt catcattttc
    48841 cttttatcgg cttagtacca gccgtttgct aaccagaatg ttttagcagc atcccatgaa
    48901 ccataacgag atgttacata ttgttctgct acacgttctt gattggcagc tgaatagtcg
    48961 ccgtttaagt atgaagcatc taattgataa cggccgatgt aacgtccgtt agtagctgtg
    49021 tatgaaccgc ctgattcttt ttgtgcgatc cattcttttg cagagcttga agttggcgct
    49081 gttgcagcag ctggggcagc aggagctact tcaactgttt caacaggtgc aacgtatgta
    49141 tgttcttgcg ttgctgtttc agttgtagat gctgtatttt ctgttgtttt gttttctgtt
    49201 gttgctgaag aatcatttga agttgggatt gttaattgtt caccaacata aatgcggttg
    49261 atgtttgcga tcgaattttt ttcagcaatt gcatcgatca ttgagttgtc tcctgcaaat
    49321 ttttgtgaga tcttagataa tgaatcacct gattttactg tataaacttc atcagcgtga
    49381 gcatttgtag ttcctacaaa cattgcagta gcaccagcag caaaagttgt acctaaaaca
    49441 attttcttaa atgaattcat attaaactcc tttttttctc cgttttttat tctttcgacg
    49501 ctattaactt tatcatttag aaatatttca taggtaaaag aaacatgaca tttaatgaca
    49561 aaataacgaa ttatttaata tttgtaacat ttaaacaaat atttttttga tacaaaacca
    49621 taaaagcctt gttgtataag caaagtaatc gtttttctat gtttttttat ttttgaatga
    49681 aaaacgcaga ttctgtaaca ttcactgcaa taatccataa aaaaaagcaa aaaaattttt
    49741 gatttttatc aaattctctt aaaaaaatgt aaaaaataca aaaaaaccag taattgttac
    49801 aacaattact ggacaaaaac tttgaataat gttaactatt tttttatttt aactttctcc
    49861 gcaataattt ctgggcatgt tccaattcgt ttataacgac ttcttctgtt tctttagcta
    49921 atatttcatc taatacatca agccattttt ccggttcttt tgttcctaga cgtccaatag
    49981 cccaagctgc tgttcctctg atgacagggc ggacatctgt taaacattct gaaatctcag
    50041 gcaatgccgt tcgatcacct agattagcta aagcaatcaa tgcgtttctc tgcaaaggtt
    50101 tcttcccacg ccatgaacca gctaaatgcc caaattgctg tttgaagtct ttattagaca
    50161 tcgaaagcat tggctttaat tttggatata tttcgtctac ttttggttcc atctcttcat
    50221 gaaaatgaaa atcttttcct tgattgtaag ggcagactaa ctggcagata tcacatccat
    50281 aaatgacatt tcgcattttt ttacgatatt cttccggcat catccctttt gtctgagttt
    50341 gataagacaa acatcgctgg gcattcattc ttccgtcacc aagcaatgct tttgtcggac
    50401 aagcagtcac gcagcgcata cagtcaccgc aaccaaattc tcctggttta tcaggctcaa
    50461 atacaatatt agtaacgatc tcaccaagat agacaaatga accgaactct tcagtgatca
    50521 acaatccgtt tcgtccaata aatcctaaac cagctcgctg tgctacagcg acatcgatca
    50581 gttctccagt atctacttgc ggagctagac gccattcctc ttctttttgc catttttctg
    50641 ctcttgtttg gatgaattcg atcaatcggt tcaaacggtc tctgagtata tcatggtaat
    50701 cgatccccca agaagcacga gcaaactgcc cgcgtttttc atccctaggc acttcttcat
    50761 ggatcctagt aggatacgca agtgcaatgg aaatgatcga tttcggctga tcaaatgtca
    50821 tttctggata aagacgctca tcgatatttg gatgttcaaa gccagaagta tggccagctg
    50881 ctttttgttc ttccaacgat tcttttaatg aatcaaaagg ttccgccgtg gtgaacccga
    50941 ttttgtcaat tcctaatcgt ttgctttctt gtatgatttc ttcttttaat gtcatggtct
    51001 tcctcgcttg ctgttaacgg ctgtataacc cataatatag tttttctttt ttcagctgga
    51061 caaactggat ctgctgatcg gcaatcttct tttcttccat ccattttttt cttgcagcaa
    51121 atacttccca ataatttgtt gaaattaatt ttcttttgtt atctaatgca ttaaaaaaat
    51181 tcaatgaaac tggttttgta cttaacagtt catggagcct tacctcttcc catggcgaaa
    51241 actcagacag atcgcgggaa tacaatactt cttcatagag atttttttgc tgtgtgtacg
    51301 tgaatgtttg cgggattttc ccaggcctag caatttctac tagacgatta taaaacatat
    51361 tcattaattt gctgttggca ataaattgac ttttataata ggccgactgg atctttttga
    51421 ttactccttc tgctttgatg actgaaaata atgcaggcca tgctttgacg gttatttcgt
    51481 cgttttgttt aactaatacg ccaggtgtga agccgactgg agaaaggaac acaaaataac
    51541 cgataccggt attttcatct aaaggctgaa attcatcaaa caaccatttg cctatgtaca
    51601 gctcttcatc tggttctgtt gtctcatttt gatttgctat gaataattta gctaattctg
    51661 cttcaagaaa ttgaaggtct tgatccttgt cggtattttc ctgctggctg atcaatcgaa
    51721 agacttcttc tttaatcgta tatttatctt tacgtgtaaa attcatagcc acaccttcct
    51781 tccttactct aactataacg gaatttcttc aaaaaaggta tctgtacgac gaaaaacagc
    51841 ataatttttt ttcatatctc ttataaaaaa tgcaaggtct gctcctcaag ctagaccttg
    51901 cacttttcag ctttcttttg tttgtgacaa accttcatgg atcgtttcaa tattccattt
    51961 catcatctga tagtaagaat ctccttgttc tccttctttt gctatggaat cagtgaacag
    52021 tttatcatag attttcaaac ccgtttcttt tgctacccgt tccatgcttc ttgagtctac
    52081 actggtttcc acgaataaaa ccggtacttc ttttgctctt atctgatcaa tgatcgcttt
    52141 catttgatca ggcgtacctt gactttctgt attgatctcc catatataag ctgctggcaa
    52201 atcatatgct cgtgaaaaat acttgaatgc cccttcactt gttactaata attttttgtt
    52261 ctcttcgata gaagcaaaac tttccttcgc ttgtgtatct aattctttta gtttttccac
    52321 atatgcttct gcattttttt tatagagtgt cgcattttct gcatcttttt cagagaatat
    52381 acgtgcgatt tcctccacat attttattcc gttagatagg tctagccaag catggggatc
    52441 tgcttttgta tgttcttcac cgctagttaa ataaagaggt tctacatttt tgctaactgc
    52501 aaaataatct tttccttctt cttttttagc cgtttccatc aagttatcga accagctgtt
    52561 acctgtttca agattcaaac cgttgtataa aataacatct gcatcgcttg cctttttgat
    52621 gtcttctggt agtacttcat attcatgcgg atctgttccg actggtacga tactgtggat
    52681 atctatttga tctgttccga cctcttttgc catgtccgcc aagatcgaat tggtagccac
    52741 gactgacaac ttttctttac ttccttcatc cgcttggtca gaagcctgct ttccgcaacc
    52801 ggctaatacc aagaaactaa ctgccaagat taaaaagagt gatttttttg ttttcatcta
    52861 tctgcttcct ttctgaaata aaattccttt tgttggagaa aataaaaaag caaggataaa
    52921 aaatgcggta catgctaaca cgatcgtagc tcctgatggc caattgtaac tataactgaa
    52981 aaacacaccg acaactgcac ttagcatacc gattcctgca gctgtaatga tcattttcag
    53041 taaatggttc gttagcaagt aagccgtggc ggctggtgtg atcaacatgg caatcaccaa
    53101 gattgttcct actgtctgta aactgactac agccactaat gtcaaaaaga acatcaaaag
    53161 ataatggatc agcgatgtgt tcagcccata agcttttgcc attgtcggat cgaatgatgt
    53221 gatcttcaat tctttataaa agaaaaagac aaatatcaag acgattccac taacgagtgc
    53281 tgtcagcaac aaatcgcttt ccctaacagc taagacattc ccaaataaaa tatgatacaa
    53341 atctgtcgca ctctgggcat atgaaatcaa gataatccct aatgcaaaaa aggagctaaa
    53401 gacaattcca atcgctgtat catttttcaa tcggctccgc tgagtcacga aaccaatcac
    53461 tgctgctgtt agcatcccaa aagcagtggc tccaaagatg taactaaaac caaacatata
    53521 agaaatggct acacctggaa gaactgcgtg agagatagcg tctcccatca aagacatccc
    53581 tcgtaaaata ataaaagaac cgatgactcc agaagcaagt cctacaagca tggaagtgac
    53641 caaagcgtat tgcaggaatt gataattcat taatccatca ataaaggatt ggatcatttt
    53701 ttctctcctc cttttactaa atgtctgatg atctcaccat aggccaattg aaggttcttc
    53761 gatgtaaaga cttcttgtac tggaccggaa gcgatcagct gtttatttaa aagaataacc
    53821 tcatcgaaat attcttctac tttatgaaga tcatgatgga cgatcaaaat cgtttttcct
    53881 gaattcttca attcctgcaa gatgtcaaag atctttcgtt cacttaacgc atcaatccct
    53941 acgaatggtt catctaaaaa gatccattct gctccttggg ctagagctct tgcaataaaa
    54001 actctctgaa gctgtccacc cgatagttcg ctgatctgtc ttttggcata ttcttccatc
    54061 cctacttttt tcaaagcttg tcttgcacgt tctttttctt ttttcccagg tctttgtcca
    54121 attcgtaaag atggatatgt tcctaaaagt acaacgccta atacatcaat tggaaaggaa
    54181 agatccaatt cacttcgctg ttccacgtag gctatttttt tacggactga gtttaccgac
    54241 tgtccagaaa aggtgacttt accagtagta gctggtatca actctagcaa agatttcata
    54301 aatgttgatt ttcctgcacc gtttggtccg ataataccgg taattttttg tggatttatc
    54361 gtcaagttga tagttttcaa aacagttttc ccttgataag cggctgaaag gtcttgaatt
    54421 acaatggccg tacgttccaa atcttacact cctttttagg tttacctaac tttttattta
    54481 aatatagttt aactaaaatg gaaagcattt tcaagtagaa tgatgaaaaa gtttttttcg
    54541 aattttcctc gcattttatg aaaattttct gtagaatcac atcaagagtt caataaggct
    54601 aacctaataa tgaaaaacat gtgttgaaac gtttgattat tttttcttgt tgactcaaca
    54661 acgaaaggag tttttgtatg gaagaagaaa agttaactcg aagtcttagt gcccgtcata
    54721 tccaaatgat cgcactaggt ggaacgatcg gtgtcggtct gtttatgggt gcctcctcaa
    54781 ccatacgttg gacagggccc tcagtgatgg gagcctatgc gattgcagga ttctttttgt
    54841 atttgattat gcgtgcttta ggcgaaatgc tttacgttga tccttcgact ggttcttttg
    54901 caaattacgc gagcgagtac atccatcctg tggctggcta cttgaccgct tggagtaata
    54961 tttttcaata tattgtcgta ggaataagtg aagtgattgc tgtaggatct tatatgaatt
    55021 attggtggcc tgatttgccg gcaattattc ccggaatcat tgtcgtcttg tttcttatgc
    55081 tggcaaatct tatttctgtc aaggcgtttg gcgaattaga attttggttt tcgatcatca
    55141 aagtcataac gatcattttg atgatcattg caggtcttgg ggtaatctta tttggatttg
    55201 gtaatcatgg tcaggcagta gggatttcaa atctttggaa aaatggtgga ttcttcactg
    55261 gaggcgtcaa aggatttttc tttgcattat cgatcgttgt tgcttcctat caaggaatcg
    55321 aactgatcgg aatgactgct ggtgaagcag agaatcctaa aaagacgatc attgaagctg
    55381 tccagtccac tatcggtcga atcttgattt tttatattgg tgctattttt atcattgtga
    55441 gtatctatcc gtggaatcaa ttgagtgaga ttggttcacc ttttgtacaa actttttcta
    55501 aagtcggcat tacatttgct gcaggactga ttaattttgt cgtgattaca gcggcattat
    55561 caggttgcaa ttcagggatt ttcagcgcaa gtcgtatggt ctatacactt gccataaatg
    55621 gaaagatgtc taaaaaattt ctgaaactat ctcgtcacgg tgcgcctttt tatcctgtcg
    55681 tagcaatctc aggtggaatc ttaattggtc tgatcttaaa ttatcttcta ccaatgttca
    55741 tcaaccagtc agaaaatatt ttcgttttcg tatacagctc aagtattttg cctggtatgg
    55801 ttccttgggt agtgattttg atcagcgaga ttcgcttcaa aaagaagcac gcagataaaa
    55861 tgcatgatca tccttttaaa atgccactat ctccttatac gaattatgtg acacttgctt
    55921 ttttagctat cgtattgatt ttcatgttta tcaatcctga aacgagaatc tcattgatta
    55981 ttggactcgt tttcttgctt tacatgacga tccattactt tgtacgcgaa aaaagaaccg
    56041 gaaaataaaa aaagaacgaa gcttcacctt agtggaagct tcgttctttt ttattgcttt
    56101 tatcaattca attttagcgt ctcaccggga gtcaggaaat aattctccat gctcatccca
    56161 ttcagcgaca agatcgtttc tactggtacg ccagttcgtt cggctatttg atttggacct
    56221 tctccttcca aaactacggt tgtcgcagcc tgtgaagtcg cgctgttggt attagtttca
    56281 gaggaatctg ttgtgtcttg tgttgttcga gcttgcattt cagaagcttc taccgactct
    56341 gctgtctcag aatcagaaga tgttgtgtct tgtgtgcttg ttgactctgc ttgaagagag
    56401 gcgctagtct gcaaataaat atcggaaatc ttagcgacat gattcgtata attagccgat
    56461 aattgattga tcaaagtatc taagtctaca ccgtctttat tttctgctgc ctgatacgct
    56521 gcacgtaatt ttctgatccc ttcgtcggag attgcttgaa gctcacgtgc tttttggtta
    56581 gcaactgctg ataaaccagc tattccctct tgatttccct gaatttctgt ctggtattct
    56641 tcaatcaatg caggcgtctt ttcttcgatc tttttcgaat aatcatttac gattgcttga
    56701 agttgctctg gcaaaccatt tgctgttttt tcttcagaag tttgtgtctc ttttgtttta
    56761 gttgatgact cacttgtttg tttcgtctct gttttctttg tcgttgtttc cgttatggtc
    56821 gtacttttcg cttctgacga attttttcca tgaaaatata gacccgcaac tcctcctgct
    56881 atgatcaaaa acacggcaac tgctgcccca atcatgatca tccgcttacg agctgcctgt
    56941 ttttgctgtc ttcttcgggt catccgaaca ttttctcccc actcattttc atcatacatt
    57001 tttttcacca ccaattttta tgtataatag cgttatcaaa cgcttcatat tcttattgta
    57061 gcaaataatt gtcgctgtgc acatttttat ctttgttatt tataagaaaa tttcaccagt
    57121 tgagatgatt ccaagattgt ccgtcgattt ctccttgcag ctgcattgtt cgttcgtcta
    57181 tctcagccat cagtttcttt atttcatata agagcgcacg gtcttgatat tctgattttt
    57241 cgcttaattc atctaattgt tggatcagcc aatcatttgt cataatgaag ttcctttcat
    57301 ttcttgcagt gtaaaggtca agtcttcgat ctgctctttt gcctcagtca gtgcttctac
    57361 gatatatgct tgtttttcag attcttcttc ctgcattttc tgattttcct gtactctttg
    57421 aataaaccag tcaatccgct gagtcagcga tggtttgcct tccaatgaga gatactgctg
    57481 ataagcaatt agcttctccc aacgtttttc ctgggataaa tacataaatt gtgctaaaac
    57541 gaatggcgga agataggtca tatggaattt atttgcgatt cgctgatacg gcctcaaaaa
    57601 ttcggaaatc gtatattctt cttttcctcc agcttggtat tctttttccg ccacacctgt
    57661 tgtcaatacg attcctagtt ctttcccttt taatacatgt gctgctcgtt ccaagacatt
    57721 atcttgccaa atttttaaat gagcaggaga actataccag taaaacggaa actggaaaat
    57781 gatccgatca tgctgggcca agagctgtag ttcagtctct atatctattt ttccgtctgg
    57841 ataacttgat tccaaatgat gccaagtagc tggtaaacca gcagaagctt ctttgaaaaa
    57901 ttgctgattt aaagattctt cgatcgttgg atggctaatg atgataagtg tacgcatccc
    57961 ttttcctcct ttttagtctt cgctttacag tgtagcataa ccgccacaag tttcttttgc
    58021 cgatgcttgt cattttaacc agactaatca ggttgtccaa gaaactgcgg tttgtttttc
    58081 caactgtttt ttcaaggtat ccaaagcaat attcttaaaa ttttcgtttt tcatacgttt
    58141 acgatagttc gtagccgttt ctccggtact ctttttgaac attcggctaa atacgactag
    58201 actattgaac cctacttgat aggcaatact ttccacggat tcatccgtca gagaaagaag
    58261 aaacgcccct cgattgatcc gtaccccgat caaatattcc ttgatactgg tacccatatg
    58321 atttttgaat actcgcgaca aatggctccg attgaccgct aaatgctggg cgatttcctc
    58381 aacagacaat ttttcagcat aatgtgcctc gatgtatttg actgtttcaa cagctaaaga
    58441 ggaatgaacc ttttgtacac caccgctgac ctttccgcca tcttttaaaa ggactgataa
    58501 aaaacggtag gttaatgctg ttaactgtaa ttcattttcc aaggtttctt ccgtatcttt
    58561 catgcattct aaaataatgt cgatatattt ttgtatgtca gaagagacca tcgtgtattg
    58621 gtcttctctg aaaagcgact gccgaatgat ttcttctgca gcactcccac caaatgaaag
    58681 ccagcaatac atccacggat cttctccatc tgataagtaa aacgtcgagt ctcctggacg
    58741 aatcaagaac agatcacctt ttttcaattg gaattgttga tttttcacat gataagatcc
    58801 tttgccttcc atcacgacat gcaggatgta atcattgcga atagcaggac caaaagaatg
    58861 aaacggcatc gttttagaga aaccacaaaa atcaaaatac aattcttttt ctacttgttg
    58921 atgttccttt tttaaaaaaa tcgattgctc cacgtctatc cctccttact cctttagtat
    58981 aatgcaacaa aaagttaaat aaaagtcaca gaaatatatt aaaaaggaag cgatttcttg
    59041 ttaagtttaa gtcattaaaa gatctttgtt attcgttgta accggtttac ttagtattat
    59101 atattgaaca ggagaggaat acagattatg aaaagcaaaa tgatccaacg tgtgtcctac
    59161 gctttaggcg cttttggaca cgacacattc tatgttacat taagcactta ttttatggta
    59221 ttcgtgacaa gccagatgtt cgcaggaaca gataaggcaa cgaatgcaaa aatgattgct
    59281 acagttacaa gcttagttgt aggtatccgc ttagttgaaa ttatttttga tcctttgatt
    59341 ggtggcatca tcgataatac tcgtacaaaa tacggtaaat tcaaaccatg gttagttatc
    59401 ggcggcgttg ttagttccgt actcttggta gcaatcttta ccaatttctt tggcttagct
    59461 actcataata cgactttatt tatcatatta tttgcaatcg ttttcatctt attggatagt
    59521 ttttattcat ttaaggatat cgctttttgg tcaatgattc cagctttgag tacggaaaca
    59581 aaggaacgtg aaaaatttgc tacgtttgct cgtttcggct cttctctagg tgcaaatggt
    59641 actactctag tcgttgtccc tatcgttact ttctttacct atcttgttac tcataaacat
    59701 attgaaggcg cttcaggctg gttctggttc ggtgtgattg ctgctgttat ttcaggcggt
    59761 actgcgatta tcactgcctt gggcacaaaa gaagtcgata ctgcgatccg tcagcaaaat
    59821 gaaaaagctg ggatcaaaga tgtgttcaaa gcagttgctc aaaatgatca gttgatgtgg
    59881 cttgcccttg cttatatcgc ttatgcgatt gccaatgtag caacaactgc cttattattc
    59941 tacttcttca aatatgtact tggccaacca actgaatttt ggatcgttgg tctagttgct
    60001 gccttacttg gtttagtagc tgttccacta ttcccaatgc ttacacgcgt catctctcgt
    60061 cgctacgttt accttggagg gatcgcaatg atgatttctt cttacttttt ctttacgatc
    60121 gcaggttcaa gtttgccaat cgttatcatc gggctagtat tgttctactt ccctcaacaa
    60181 ttgattttct tatccgcttt gatgacgatc acagactctg ttgaatatgg tcaatggaaa
    60241 aatggtatcc gtaacgaagc tgttactcta tcaattcgcc ctttactaga taaaatcgct
    60301 ggtgctttgt ctaacgggat cgtagggttt gtcgctatcg cttctgggat gactggtaat
    60361 gctactgctg ctgatatcac tgctcatggc gtaacgactt tcaaagctta tgcattctat
    60421 gctcctgctg ctttgatgat tttctccgct attatttttg cttggaagat tacattgaca
    60481 gagaaaaaac atgcacaaat cgttgagaaa ttggaaaaca aattggctcc agctgataca
    60541 atggaagatg aacttccgat gcagtagttc cttcccatta agaaaggatc ttgaaaatga
    60601 agattacaga aaaagatttt ggccaaggtt atcacttgat aaccttggag aacaaaaaca
    60661 agctagcact ttctatctct gatttaggtg ctagaatcgt cagtttaaaa tcaaatgatc
    60721 gagaattagt tttgggattt gacaccgctg aagaatatat cgaaaaagat ccgtatatcg
    60781 gtgcttctat cggtcgcacc gcagggagaa tcgaaaatgg ccgcttttct ctcaatggaa
    60841 aaacttacca attagccaca gatccaaaaa ctggacataa tctgcatggt ggtgctcctg
    60901 gatttgaatt aaaaaaatgg tcttatgtca ttttgaatgg cgaaaatgaa gcttctgtca
    60961 tttttactac tacaagtccc gacggagaac atggttttcc aggtacaatg gatgtggaaa
    61021 tccgctatac tttgacaaaa gataatatct ggcgagtgac ctctcgcggc accagtgacc
    61081 aagatacttt attcaatccg acaaatcatg tttacttcaa cttgacggga gatgcttctc
    61141 agtcaatcga tcaacatgag ctttggctca atagcgaagc ttatgctcct ttgcgaacag
    61201 atagtattcc tataggggta aaagaaaatg ctgcaggaag tgctttcgat tttcaaatac
    61261 ctaaaaaatt agcgtccgtt tttgctagtg atttggatca aaaaaatctt gttgacggaa
    61321 tcgatcatcc atttttctta aaagaaaccg gcttgggtaa agaagccgct cgcttgacta
    61381 gccccgataa aagaatccaa gtagatattg ctacagatgc ttctagtgtg gttattttca
    61441 ctgcaaattt cggcacagaa acaccagaaa tgcgcaaccg aaaactggca catcacggtg
    61501 gcatcacatt tgagactcaa acagctccag gtgcagagcg cttctcagca tttggttcga
    61561 ttcatttaaa agccggatca gtatttgaaa cagtaacaga attcaaaatc aaaacaagaa
    61621 aggaataact catcatggaa atcaaaagaa gcttaaacac aaaatttgcc gaaacattcg
    61681 gacctaaaaa aactacacaa tacttctcac caggacgcat caatttgatt ggtgaacaca
    61741 cagattacaa tggaggccat gtcttccccg cttccatcac ttatggaacg caaggtgtag
    61801 cagcacctcg agacgataat aaaatattag tttattccac aaactttgac gatatcggtg
    61861 tcattagttt tactttagat gagctagaat atgataaaaa agcaaactgg gcaaattacg
    61921 taaaaggaat ggtccttaaa ttaaaagaag ctggacactc aatcgatcat gggtttgagt
    61981 tattagtgga aggaacaatc cctaatggtg caggactttc cagtagcgct tcattagaat
    62041 tattagtagg tgttgtatta gaagatctgt ttgatttaaa aacagatcgc ttggaactag
    62101 tccaaacagg taaaaaagta gaaaatgaat tcatcggtgt caattcaggt atcatggatc
    62161 agtttgccat cggcttcggt gagctagatc atgcaatctt attagataca aatacgctga
    62221 aatacgaaat ggttccagtg aaactagatg gttatgcaat cgtcatcatg aatacgaata
    62281 agcggcggga attggcagat tcaaaataca atgaacgccg tagcgaatgc gaagaagcct
    62341 tggcacgttt gcaaaaaact ttgcctatct cttctttagg agacttagat gaagaagaat
    62401 ttgaatcaac tattgaccaa atcggcgatg atacattgat acgcagagct cgccatgccg
    62461 tttctgaaaa tcagcggact ttgaaggcaa aagctgaatt agaagctggg aacttagaag
    62521 catttggtca actgttaaat gattctcacc actctcttcg ctatgattat gaagtaactg
    62581 ggatcgaatt agatacacta gtagatgctg ctcaaaaaca agaaggtgtc ttaggtgcac
    62641 gaatgacagg agctggattt ggtggctgtg cgattgctct tgtcaaagaa gaaaatatac
    62701 ctgccttcaa aaacaatgtc tatgatgaat acatgaaagt tgtcggctat gctccggaat
    62761 tttatgttgc acacattgga aatgggacaa caaagatcga tccagaagct gttcatgttt
    62821 gataaaaaaa tcaacgatct cagctaaaaa caaatagata aaaataacct ctcagcaatt
    62881 tccaaatgtg agccttttgc tcgtatttga aaattgctgt tttttattga cacggaaaga
    62941 gaacgtgtgt tctaattgtg ttgaagaggt gattgttatg tgggcgaatc aaaatccggt
    63001 atttgtttat gaaaaagaac cttcaagaga tattttatgt attgactgca aatcttttta
//
LOCUS       DAFEKH010000009        60532 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.009, whole genome shotgun sequence.
ACCESSION   DAFEKH010000009
VERSION     DAFEKH010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 60532)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60532)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60532
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.009"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(20..1039)
                     /locus_tag="LP386_000654"
     CDS             complement(20..1039)
                     /locus_tag="LP386_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1917915.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(1061..2068)
                     /locus_tag="LP386_000655"
     CDS             complement(1061..2068)
                     /locus_tag="LP386_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBL1917916.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            complement(2061..2726)
                     /gene="pgmB"
                     /locus_tag="LP386_000656"
     CDS             complement(2061..2726)
                     /gene="pgmB"
                     /locus_tag="LP386_000656"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBL1917917.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            complement(2719..5013)
                     /locus_tag="LP386_000657"
     CDS             complement(2719..5013)
                     /locus_tag="LP386_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBL1917918.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            5273..7438
                     /locus_tag="LP386_000658"
     CDS             5273..7438
                     /locus_tag="LP386_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL1917919.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            7742..8575
                     /locus_tag="LP386_000659"
     CDS             7742..8575
                     /locus_tag="LP386_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBL1917920.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(8677..10377)
                     /locus_tag="LP386_000660"
     CDS             complement(8677..10377)
                     /locus_tag="LP386_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917921.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            10884..12044
                     /locus_tag="LP386_000661"
     CDS             10884..12044
                     /locus_tag="LP386_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL1917922.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            12060..12503
                     /locus_tag="LP386_000662"
     CDS             12060..12503
                     /locus_tag="LP386_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1917923.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(12986..13516)
                     /locus_tag="LP386_000663"
     CDS             complement(12986..13516)
                     /locus_tag="LP386_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HBL1917924.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            13621..14172
                     /locus_tag="LP386_000664"
     CDS             13621..14172
                     /locus_tag="LP386_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBL1917925.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(14325..14798)
                     /locus_tag="LP386_000665"
     CDS             complement(14325..14798)
                     /locus_tag="LP386_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBL1917926.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            14936..16408
                     /locus_tag="LP386_000666"
     CDS             14936..16408
                     /locus_tag="LP386_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBL1917927.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            16405..17115
                     /locus_tag="LP386_000667"
     CDS             16405..17115
                     /locus_tag="LP386_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HBL1917928.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            17467..17751
                     /locus_tag="LP386_000668"
     CDS             17467..17751
                     /locus_tag="LP386_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HBL1917929.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(18032..18451)
                     /locus_tag="LP386_000669"
     CDS             complement(18032..18451)
                     /locus_tag="LP386_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HBL1917930.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(18453..19037)
                     /locus_tag="LP386_000670"
     CDS             complement(18453..19037)
                     /locus_tag="LP386_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HBL1917931.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(19084..20559)
                     /locus_tag="LP386_000671"
     CDS             complement(19084..20559)
                     /locus_tag="LP386_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HBL1917932.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            20740..21051
                     /locus_tag="LP386_000672"
     CDS             20740..21051
                     /locus_tag="LP386_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917933.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(21166..23502)
                     /locus_tag="LP386_000673"
     CDS             complement(21166..23502)
                     /locus_tag="LP386_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1917934.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            23644..24312
                     /locus_tag="LP386_000674"
     CDS             23644..24312
                     /locus_tag="LP386_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1917935.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            24315..25358
                     /locus_tag="LP386_000675"
     CDS             24315..25358
                     /locus_tag="LP386_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL1917936.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(25595..26476)
                     /locus_tag="LP386_000676"
     CDS             complement(25595..26476)
                     /locus_tag="LP386_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL1917937.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            26635..27363
                     /locus_tag="LP386_000677"
     CDS             26635..27363
                     /locus_tag="LP386_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HBL1917938.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            27519..27836
                     /locus_tag="LP386_000678"
     CDS             27519..27836
                     /locus_tag="LP386_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBL1917939.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            27829..28437
                     /locus_tag="LP386_000679"
     CDS             27829..28437
                     /locus_tag="LP386_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HBL1917940.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            28492..29283
                     /locus_tag="LP386_000680"
     CDS             28492..29283
                     /locus_tag="LP386_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HBL1917941.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            29421..29909
                     /locus_tag="LP386_000681"
     CDS             29421..29909
                     /locus_tag="LP386_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBL1917942.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            29960..30832
                     /locus_tag="LP386_000682"
     CDS             29960..30832
                     /locus_tag="LP386_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBL1917943.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            31008..31370
                     /locus_tag="LP386_000683"
     CDS             31008..31370
                     /locus_tag="LP386_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBL1917944.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            31379..32131
                     /locus_tag="LP386_000684"
     CDS             31379..32131
                     /locus_tag="LP386_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1917945.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDVGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            32145..33947
                     /locus_tag="LP386_000685"
     CDS             32145..33947
                     /locus_tag="LP386_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1917946.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            34224..35264
                     /locus_tag="LP386_000686"
     CDS             34224..35264
                     /locus_tag="LP386_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBL1917947.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(35316..37460)
                     /locus_tag="LP386_000687"
     CDS             complement(35316..37460)
                     /locus_tag="LP386_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBL1917948.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(37817..39190)
                     /locus_tag="LP386_000688"
     CDS             complement(37817..39190)
                     /locus_tag="LP386_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL1917949.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(39190..39585)
                     /gene="rbsD"
                     /locus_tag="LP386_000689"
     CDS             complement(39190..39585)
                     /gene="rbsD"
                     /locus_tag="LP386_000689"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HBL1917950.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(39613..40530)
                     /gene="rbsK"
                     /locus_tag="LP386_000690"
     CDS             complement(39613..40530)
                     /gene="rbsK"
                     /locus_tag="LP386_000690"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBL1917951.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(40638..41651)
                     /locus_tag="LP386_000691"
     CDS             complement(40638..41651)
                     /locus_tag="LP386_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBL1917952.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(41732..42331)
                     /locus_tag="LP386_000692"
     CDS             complement(41732..42331)
                     /locus_tag="LP386_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBL1917953.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            42517..43218
                     /locus_tag="LP386_000693"
     CDS             42517..43218
                     /locus_tag="LP386_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1917954.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            43228..45939
                     /locus_tag="LP386_000694"
     CDS             43228..45939
                     /locus_tag="LP386_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1917955.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEGL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            46390..48018
                     /gene="treC"
                     /locus_tag="LP386_000695"
     CDS             46390..48018
                     /gene="treC"
                     /locus_tag="LP386_000695"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HBL1917956.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(48078..49259)
                     /locus_tag="LP386_000696"
     CDS             complement(48078..49259)
                     /locus_tag="LP386_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL1917957.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            49511..51034
                     /locus_tag="LP386_000697"
     CDS             49511..51034
                     /locus_tag="LP386_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HBL1917958.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(51103..51831)
                     /locus_tag="LP386_000698"
     CDS             complement(51103..51831)
                     /locus_tag="LP386_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1917959.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(51844..53124)
                     /locus_tag="LP386_000699"
     CDS             complement(51844..53124)
                     /locus_tag="LP386_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBL1917960.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(53265..53867)
                     /locus_tag="LP386_000700"
     CDS             complement(53265..53867)
                     /locus_tag="LP386_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBL1917961.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            54112..54318
                     /locus_tag="LP386_000701"
     CDS             54112..54318
                     /locus_tag="LP386_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1917962.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            54630..55349
                     /locus_tag="LP386_000702"
     CDS             54630..55349
                     /locus_tag="LP386_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBL1917963.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(55430..56113)
                     /locus_tag="LP386_000703"
     CDS             complement(55430..56113)
                     /locus_tag="LP386_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HBL1917964.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            56331..58517
                     /locus_tag="LP386_000704"
     CDS             56331..58517
                     /locus_tag="LP386_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBL1917965.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            58863..59273
                     /gene="spx"
                     /locus_tag="LP386_000705"
     CDS             58863..59273
                     /gene="spx"
                     /locus_tag="LP386_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBL1917966.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            59287..59643
                     /locus_tag="LP386_000706"
     CDS             59287..59643
                     /locus_tag="LP386_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HBL1917967.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
     gene            60316..>60532
                     /locus_tag="LP386_000707"
     rRNA            60316..>60532
                     /locus_tag="LP386_000707"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT        19466 a        10729 c        12211 g        18126 t
ORIGIN      
        1 tatttagtga gtcagctatt tagtatgggt tttctaaagg aacgactgtc tctcttttga
       61 tcaagcgatg agggatgacc aaacgtacgc cactgctcaa ttcttcatgg atcaattcgc
      121 gcagcttttg catagcgaca cgtcctaatt cggagatatc gatatcgata cttgtaaggt
      181 aagggtgtgt taatgttgag aagatcgagt tgttgaagct aatgacggag agtgtctctg
      241 gaatgacata gccatacatt tgcgccaact gcatcgtgcg aagggcgaag atatcgtcaa
      301 tgaccaccaa tgctgtggct tcgttttctt tcaacgtttt ctcaaaggac agataatcct
      361 ccggatgctc tagtactaca ctggataacg caggaagacc agccatcatc attgcttttt
      421 gataaccgaa atatcgttcg aaatacaaac tttcatgagt cgtgtttgtc acaaacagga
      481 tattcttatg tccattctgg atcaaaaatt ctgttgcttg tttacctaga agctggttat
      541 cattatctac ataaacgatt tcgttctcat gatgataagg ctgtccgatc aaagtgaaag
      601 ggatgtggtt ttggtataaa taatcaatga cagtatcttg actatctgaa tacactagaa
      661 taaaaccatc tacttgtttt tgtaaatgca tacgctggac gttctctaac agcaattcaa
      721 aatttttagc agtagcgatt gctgtagtca tatcataatt ccgcgcttct tcgttgattg
      781 cttccatgat ctcaagataa aatgggttac cgatccgctc ttttgaatca agagggggta
      841 agattacgcc gatggcactg gaaatgcgtt ttcctagatt gcgggcagtc atgttaggaa
      901 cataacctag ttcatccata atttttcgga ctttcttctt tgttgtctcg gaaatactag
      961 gatgatcgtt gatgacacga gagacggtcg aggtggcaac accggctttt ttcgccacat
     1021 cttttacggt aatagccatg ataaaaacac ctttctcttg ttattgtgca gagaaccgat
     1081 aaatcgtctg actgatccgt tcttgaccag gatggaggtt gatcgatcca aatttgggga
     1141 aatgaacgat atcagggatt tcttgcggtt cgattgctaa tccgtagttt gaatgcatct
     1201 gttttccatt gacagagaaa tcagcttcga atccagtcgt agaaaataat accatacttt
     1261 tattagaagt tgctatagtc atttggcgac cagaatgctt ctcgaataat tgtaaggaag
     1321 ttttggaaag cctaggatga tgcaaaagaa atacatcatc tagtccatct ggataacatg
     1381 caaggatctc ttgcagtgtt ggggattttc taaagtcgat tggcagtttt tctttttttg
     1441 tccaatttcc agtaggcagt ttttcttgat ctaattcaag cacaccatct aaaaagaccg
     1501 ttaactgatg ttcatagatg tctcttgttc catttcctga aaggttgaag taggcatggt
     1561 tggtcggatt gcagatggtt tcaacaaggc tactagcaga ggttgtcatc tctaattcgt
     1621 tttttgttaa acggtaagtg atcgtagcag tgattggtcc tggataggta gaaaattcat
     1681 cttttaagta aaagaccaca cctattgatg atggagtttt gaaaacttct acttcccaaa
     1741 attggaaaga ccagcctttc gtgccaccgt ggatatggtg tgatccgcag tttttctcca
     1801 atctatgctc accccaagaa gcatcccgga tccttccggc tacaggtccg acagttgctc
     1861 caaaaaagct tttgtctgtt agaacatctt cgaaacgatc gtaagacaat aaaacatttt
     1921 ctgattttcc ttctttgtct ggtgcgaaga tttggtgcag gcgggcaccg taattgagaa
     1981 gaacgacttc taagtagtcg ttcttcaatg tgattttctt tatttcagtc tctggaactg
     2041 gtacgacgga gatctctgga ttatccatgg tcatgccact tttctttcaa gtaatcgatc
     2101 gtaagaaaag tcgtatcagg gacaagcggg atctcctctc caaggtcttc agcacgtccc
     2161 acgccaattg gttgagcgcc acttgagagg atggcttgga taccggcttg cgcgtcttcg
     2221 atcccgatac attcttctgc ttttagtccg acagcttttg ctgcaaggag gaagatatct
     2281 ggcgcaggtt ttccgtttgt tgcttctgcc gggtcggcaa tagcatcaaa gtaaggtgta
     2341 agacccattt tttcaagtag gaatggcccg tttttacttg cagaagcaag agcaatcttg
     2401 attttttctt cttttaaaga atccagtaaa ggcacgaccc cggggaagac atcttttggt
     2461 tcgatcgtct ggatcatctc taaataataa tcgttttttc ttttcgctaa ttctgcaaat
     2521 tcttcctttg aaaaagagtg ttcttttccg ccataagcta aaagcaaaga gagtgagtct
     2581 tctcggctga cgccttttag ctgttcgttg aatgtgtggt cgatcgtaat gccgatttcc
     2641 tgaccaagct ttcgccaagc acgataatgg aattcagcag tatcggtaat gacaccgtct
     2701 aaatcaaaca ataccccttt aaacatttgc ttcctccttt cttagcgtta tttctagacg
     2761 atccgctaaa gaataagact gttcatagac gtaaatttct agaggagaac cttctaataa
     2821 ctcgaaagta acttgttcat ctgtgactga gatgaacaat aaacgtccgc gataattgat
     2881 atggaaagaa taagctttcc aagtttttgg cagaaatggt gcgaatctca actgatcatg
     2941 ggcagttttc atttgagcaa atccttggac aatcgacaac cagctaccag tcatggaagt
     3001 gatgtgcaag ccgtcttctg tgtcgttatt gtaattatcc aaatccaagc gagctgttcg
     3061 ctggtacatt tctacagctt tgctttccat tcctaattct gctgctaaaa tcgaatggat
     3121 acttggcgaa agggaagact catggacagt cattggttca tagaaatcaa agtttttttg
     3181 cttttcttct tttgtaaaag tatcattgaa gaaataaatc ccctgtagta catctgcctg
     3241 cttgatgaag caagatctaa ggattttgtc ccaagaccaa tgctgattca gaggaagatc
     3301 gcttgtggga atatcggata caggcatgag atctttatct aagaatgtgt catgctggac
     3361 aaagattcct aattcttcgt caactgggaa gtacatgttc tctgcgatat ctttccattt
     3421 ggctagttct tcttcgctga tagtgatagc agcttctttt tgataagtta aataattttc
     3481 tcgcgtgtaa cgcaagaccc aagctgcgat cgtatttgta taccaattgt tattgatatt
     3541 gttctcatat tcgtttgggc cggtcacacc gtggatcatg tatttatttg ctcgttttga
     3601 aaaatggaca cggtctgccc agaagcgtgc gatttctgct aaaacttcca gtccttcatt
     3661 tttcaaatat tccgtatcgc cggtgtaatt cgtataattg tagattgcat aggcaatcgc
     3721 gccatttcgg tgaatctcct cgaatgtgat ttcccactcg ttatggcatt cgacaccagt
     3781 gaaggtgacc ataggataaa gcgcgccttt taatccttgt tgctgagcgt tgtggattgc
     3841 ttgcggcagt tgattatgcc gatatttcag cagattctta gttacttcag gtttggctaa
     3901 agcaagataa agagggacag catacgcttc tgtatcccag taagtggctc cgccgtattt
     3961 ttctcctgtg aatcctttgg ggccgatatt caatcgttca tcttcgccgt agtaagtaga
     4021 gaatagttgg aacaaattga atcgaatacc ttgttgtgct tcttcgtctc cttcgatgac
     4081 cacatcggca agcttccatc gttctgccca agccgctgtt tgctcttctt ttgcttggat
     4141 ataattgttt gtctggttcg ttaattctga gacagctttt tctgcttgct gcgcttctgg
     4201 aatatctcta ctagtaagaa cgataatttc tttttccact gaccatgtct caccttgaga
     4261 taattctgca gacaagcaac catgtaatgc taaagtatct tcgtgatagt cagggatgac
     4321 tgattttcca ttaacgaaat ggcgcattgc tgcagtaaca gtaaattgtt caatcccaaa
     4381 gttgtttgga atagttttag tcgtcaaata gccgatttct tctatagttc cacgatcaat
     4441 ctcattccaa aaatgttcat catagttgct gtcttcgttt tgaacatttc catccaattt
     4501 tgatacgagt ttgactgttc cgctaccttc aagcatttct atagttaaat agatataagc
     4561 tgattctttt ttgacaatgc tcagaaaacg ttcgaaggaa atgcgtactt tattagtaga
     4621 agtagtgatt gtgaatgtac gagataatac accatttttc atatctaatt cccagtaaaa
     4681 gtcttctggt tccaaagaag ccaagtcgat cagctgatcg ttgatcgaaa tatctatcgc
     4741 gataaagttc aaggcgttga tcacttttcc aaagtattct ggataaccat ttttccacca
     4801 gccgacacgt gtcttatcgg gataccagac acccgccaaa taagtacctt gatggtggtc
     4861 ccctgagtaa gtttcttcaa agttcccgcg catccccata taaccgtttc caatacttgt
     4921 taaagattct tgcagtcgaa gatttttttt atctaattgt gtcgtgctga ttttccatgg
     4981 atcaatagca aatagtcgtt tgatctgttt catttttctc ctcctaatga gctgttttat
     5041 acgttcataa taaacgcaac cgattgcaca agtcaataga caaaagaaaa tatttcatag
     5101 aaaaaagctt aaaaaaataa atttttagga gaaaattata gaagggaaca cacgtattat
     5161 aggttttata gaatggtata gacagaaaaa taaaaaataa agcatttaca aaaaagaaaa
     5221 cgcacgctat aatacgttta acgaaaccga ttgcgtaaag gagctaaacg gaatgaaaaa
     5281 gatatttagt tttgagtttt ggcaaaaatt tggaaaggct ttaatggttg tggtagcagt
     5341 tatgccggca gctgggttga tgatcagtat agggaaatca attcccttga tcaatcctga
     5401 ttggacgccg cttgtcacaa cgggcggagt aattgaaaat attggttggg caattattgg
     5461 taatcttcat attttatttg ctttagcaat aggaggaagt tgggcaaaag aaagagcagg
     5521 cggagcattt gcagctggga tctcatttat tttaatcaat cggatcactg gggctatctt
     5581 tggtgtcaca agtgacatgc ttgcgaatga agatgcattt acccacactc tgttcggtac
     5641 gaagatcatg gttaaaggat tttttacaag tgtattggaa gcaccagctt tgaatatggg
     5701 agtattcgta gggatcatcg ctggatttgt cggggcaatg gcttataata agtactataa
     5761 ttatagaaaa ttgccggatg ctttgtcatt tttcaatgga aagcgctttg ttccgtttgt
     5821 tgttatctta tggtcaacaa tcgtggcatt gattcttgct gtggtgtggc caaacgtaca
     5881 ggctggaatc aataattttg gtttatggat tgcagaatca caagaaagcg caccgattct
     5941 agcaccgttt ttatttggaa cattagaacg tttactattg ccatttggat tgcatcatat
     6001 gctgacgatt cctatcaact atacacagct tggcggatcg tatgagattt tatcaggcgc
     6061 acaggcgggg acacaagtat ttgggcaaga tccgttatgg ttggcttggg ccactgattt
     6121 agtgaatctt aaaggtgcag gggatatgtc gcaatatgag tttgtgttgc ataactggac
     6181 gccggctcgt ttcaaagtag gacaaatgat tggttcttca ggtatcttga tgggaatggc
     6241 ttttgcgatg tatcgtaatg tcgatcctga taagaaagca agatataaat caatgtattt
     6301 ttcagcagcg ttggctgtct ttctaacagg tgtaacagaa ccattggagt tcatgtttat
     6361 gtttgctgct gtgccattat atgtcattta ttcagtgatc caaggggctg catttgcgat
     6421 ggcagatatc ttgccattgc gggtccattc atttgggaat atcgaattgc tgactcggac
     6481 accgttagct atcaaagcgg gtctaggtgg agatcttatc aacttcgtgt tgtgtgtgat
     6541 cgcttttggt gttgttacgt atttcttagc aaatttcttg atcaaaaaat tcaactttgc
     6601 tacaccggga cgtaacggaa attacgacaa tgacagtgaa gaaaccgttg tatctaacag
     6661 cggaacagga acagcagatc agcaagtggt ccagatcatt catttgctgg gaggaaaaga
     6721 aaatatcaaa gatgtcgatg cttgtatgac tcggttacgc gtaagtgtaa atgatcgaga
     6781 aaaagtaggg actgaagaag cctggaaacg agcaggggcg atgggattga tcgtcaaaga
     6841 caatggagtc caagcagttt atggaccaaa agcagatgtc ttgaaatcag atatcgaaga
     6901 tctgctgcaa tcaggagcag agattccaga gccagaaatg gtttctacag gaaatggaca
     6961 agcaggtagt aagcaatact taggtataga acaagaacta gtttccgcag cttctggaga
     7021 agtgattcct ttatctgaag taaaagatcc ggtattctca caaaaaatga tgggtgacgg
     7081 ctttgctgtt attccaacat caagagaagt tgttgcgccg atcgctggaa aagtgacaag
     7141 tattttccct agcaaacatg caattgggct ggaaacgaaa gatggtatcg aagttttgat
     7201 ccatatggga atcgatacag tccaaatgaa tcagccagct tttgagattg ctgtcaaaga
     7261 aggccaagaa gtaggaacag gaacgaaatt agctgagatg gatcttgatg tgatccaaaa
     7321 cgaagaaaaa gatccaacga tcatgatcgt atttacaaac gataaagtag aagaagtagt
     7381 gatcaagcaa ttaggtacag tgacagctgg taaagtgatc ggctccatta aaatgtaagg
     7441 agaggttgtg aaaaagctgt cctgcatcaa gtcataagaa cagccaaaca aaaatagctc
     7501 ctcctatttt tcgtttggtt gggcttatta ccgagaagca gcagtttgaa tactgtttag
     7561 tggagaggtc gtgaaaaagc tgccctgcac caagtgataa aaacagccaa acaaaaaata
     7621 gctcctggtc cattgagctt attactgagg agttagcagg agaacactat ttgctggaga
     7681 ggttgtgaca aaaattttgt cacaaccctt ttgtttcgaa atgaagacaa ggagaaaacc
     7741 aatgaaattc atgacactca acacgcatag ctggcttgag ccagaaccag agaaaaaatt
     7801 gcaagaatta gcagataaga tcctgttaga agattatgaa gtgattgctt tacaagaaat
     7861 caaccaatta ctggaatctg aagaagtaga acctgcgaag ctaatgaagt tctgtccggt
     7921 aaagaatcaa gtacctatcc gtaaagataa ttttgcctac cgtttagttc agcttttaaa
     7981 ggaacacgga aaagagtatt tttggagttg ggaaatgagc cacatcggtt atgataaata
     8041 tgaagaagga aatgcactgc ttacgaaaaa aacattggaa agtcaggtcc ttaccgtctc
     8101 ccaatttcaa aagaaagaag attatcagac acgcaagatc ttgattggga aaacaaagat
     8161 agatgatcag gacatttttg tctcgagctg ccacttttct tggtggacag ataaaaaaag
     8221 tggcttttat tttgagtgga aaaacttgga aaactacttt ttggaaactc gcgtaccact
     8281 ttttttccta ggtgatttca ataatccagt agactctcaa ggttattata ctgtaagaga
     8341 aagttgcctt cttcttcaag attcgtatgt tgtcgcgaat gaaaaaggaa aagcagctac
     8401 tgtggaaaag aaaatagatg gttgggaaca aaatacagaa aaattgcgta tagattttat
     8461 tttcgtccct gaaggaatgc aggttaaaaa atatcaacgg atttttgatg ggatcgatag
     8521 tccaatcatc agtgatcact acggggtgga aatcgaatta gatgtgaacg aataaaaaat
     8581 ataacatata acataaaaaa actgattaaa ataaaactct ccaaacgatt ataccgtttg
     8641 gagagttttt tgatcggatg tatttatccc ttttgcctaa gcacgtaaaa gcttgtatct
     8701 atgataaata aataaacata gcaaggtaaa ccagccaatc aaagtaagag aaagaatgaa
     8761 atagaaatag attggcgttt gataatgaag cgtgagctcg ttgattcctt tttgctgctt
     8821 cacgattggg gtcccgatat ctgttacttc ataatcagtc aatgtttttc cattttgctg
     8881 tagcacagtc cgatcgtaga cgataacagg gatatgaaca gttttgtccc cagtgttttt
     8941 ccacttgatt gtcaaaagac cgcctggatg tgtttttata aaagttgttt cgttttctag
     9001 tatttcttcg ttataccggt cgtatttatt gtcttttgtc tccttataga ttggcagata
     9061 gtcaggtgtg gttttttgga aaacgaacaa gctggtagac atatctttgc tgaagaatgt
     9121 tttccttgct tcttccggcg tatcgaatag ataagtatgt cgactgacaa atgtttcatt
     9181 ttcccacttt tccagatgct ggtataagtt ctggatcgtc tgtgctgaaa aaataagaat
     9241 gccaaatata cttaaaagac ggaaccactt ttgttcagac cactggttca gtgaaagggc
     9301 aaggtaaagt agaagcaata gcgtaaatgg cacgaaaaat cgaaatggaa actggatcaa
     9361 actaataaaa ggcacatttt tttcgatcaa tgtcgtccat ggaatcaagc tagtagaaag
     9421 aaaaaagaaa acaagacttg tgtacaacac gattttttgg aataaggtgt tcttttgttg
     9481 aaagaaaata aaaagcaaaa aacctgataa tatcaatata ggaaaggcct tagggtaatg
     9541 gagccaataa ctgccatcca gatctatcgc cttttgactc atttctctgt taacaaaggg
     9601 aggaagaatc ttattcccac tgtaaacaat agctaatcct gcccaaatat ttgctgtcag
     9661 aacaaaataa agcaagaccg acttaatcag ttgaagcagt gcttttcctt tttcagtctg
     9721 gttaaaaaag taataaagat aaaaagggat atacatcaaa gctaacatga tcgaagacag
     9781 taaatggatc tgtgtcataa gtcccactga gacagcgact ttgataacag ggaacttttt
     9841 atgaaggacg aaatcagcaa tagggatcat acataaagga taaaaacaag tcccccagct
     9901 agtgaatcct tggttgatag accagtattg aatagaatac gtactcatga ataaaacggc
     9961 tactggtaca cttacccaat ttcgaacatt gacatatctc agtaaaatca gcatagaaaa
    10021 tcctgaaata agataaagaa tgaaatttga aagaatctga taatgaaacc agctacctgc
    10081 aagcaacacg atcaatcctt gtaaataagc gaaaaatggg ccgtaaacgg cattcacgat
    10141 cctgccactt tgctggaatc cataaaggga aggaaaataa tggaaatccc catatttaat
    10201 ttgttgcgcg gcatcataga accgattgta atggaatggg gcatcagcac ccaaaattag
    10261 tttatgtgtg aataaatgag gcatgagaaa tgccaaagca atgaaaaaaa ttgctaaaaa
    10321 tgggccatat tttttcaatt gtcgaactcc tttgcaaact ttagataaat tcatcatata
    10381 tcctatgcga gaggtaggca agaaattaga aaattcatga aaatatttat gaattttaca
    10441 agaaaaacat aagtgaaagt tctaaggaga gaggatgcga cataagtttt gttgcatctc
    10501 cttgttttga aacagaattt ttcttaatac tcgaaacaaa gtagcttttt catgacctct
    10561 cggtaaacgg tgttcaatca gctgcttctc ggtaataagc tcactagcct agaaaatatg
    10621 agaagctatt ttctgactag cgctcttatt actcaaagca taacgcagtt ttcacaacct
    10681 cttccttaaa cggtgttcaa aagcttgcat ctgcggtaat aagcccaacc caacaaaaaa
    10741 tatgagtagc tatttttttg ggctgtactt attacttgat gcaggacagc tttttcacaa
    10801 cctcatcggc tttcattttc tatttttttc ctgaacccat ataataaaag aaagaacaaa
    10861 aaaacttgca agggaggaca catgtgaagc agagtaagca aaaacagtct cgtcgacttt
    10921 tgtttcgttt gtttttatta atatgtatcg tcgtagggtt actgatcgct ttatatccat
    10981 tttatgtgga ttctttaaat agttttattg atcaaaaacg tatcgaacaa gtacaaaaac
    11041 ggaccgcagc tgaaattgaa gtgcagcgaa agaaaatgga ggagaaaaac caacgattaa
    11101 ctgaccaagg attcaatcct ggtactgatc ctttcaatga aaagaacaga aatgaaagta
    11161 caacatccag ccaattagag gaatggctga tcggaagtat caatatacct aagattcaat
    11221 taaatatttc actttatgat cggctcaatg gtaggatcct tgaaaatgga gcaggcgtct
    11281 tgcaaggaac ctctttcccg cttggtggaa attcgacgca ttcagtgatc tctgctcaca
    11341 gcggtttacc taatcgacgg ttatttaccg aattagatcg tttagaaaac ggagacacgt
    11401 ttattttgac tgttttgggg gagaaattgg cttatcaagt taaaaatata caagtggtac
    11461 tgccagatga cacgtctgtt ctaacgattt cagaaggaga agacttagtt accttgctta
    11521 catgtacgcc gtatatgatc aacacgcatc gtttgctagt gacaggacat cggattcctt
    11581 ataacgaatc ggtaaaaaaa gaagaaggaa aaggaaatca ggaaagaacc atgcggcaat
    11641 ggtttattct tgcaggaacg ataatagctg tagtcatact gttagtgttt atcggacgac
    11701 taatctatca gtatagatta agtaaaaaag tgcttgattt ttcatttatt attagtgatt
    11761 cgtcagggaa accggtaaat ggtagttcat tcattttgaa acataagaaa aaaacactta
    11821 ctagaaatgg tgtgccgttt tcagtacaaa gcgaccatca tgggaaagtc aagctggatc
    11881 aattgcctgg tggaacttat cgaatcgttt cagctgatga tcctaaagtt gctgtttctt
    11941 ttggtattag aaaagtaaaa caagagaaga tatacttttt tgaggggcga aaacttgtaa
    12001 aagagcttca aaaaaatggt ttttatttta aaatcaatga ataagtaagg agagaaaaaa
    12061 tgatccgcac aacaacaaaa ttgtctgcca aagaactgga atctgttcta tcgatttggc
    12121 tgcatgctaa cttggattct catgaattca ttccatcaac ttattgggag aatcaagtag
    12181 aatctgttag gaaagcttta ccagatgcag tgatttactt agcagaaata gatcaagaaa
    12241 ttattggttt tgctggggtg attgatcagt ttatcgcagg aatctttgtg aaaagggaat
    12301 accggcaaca aagaatcggt acgcaactaa tgaaaaaaat aaaagaaacc aataaaacac
    12361 tgactttgac agtctatcaa aaaaatcaat cagctattca tttctatctt tcacaaggtt
    12421 ttacaattca aacacagcaa aaagatgaag cagtaaatga ggaggaactt gtgatgaaat
    12481 ggaatcaaaa cgctgatttt tgatgaacag aataacgaaa taatgctccc agcctaattt
    12541 tttgctggga gcattatttc attttgaagt cactaattta actgtgtgaa tatgcagttg
    12601 ttacaatctt tgataaacgg tgttcaatca gctgaccctc ggtattagct caaaaaacgg
    12661 caaaatatga ggaactattt ttccatttgt ttctctaata ctcaggtcaa aacgctgatt
    12721 tcacaacctc ttgataaacg gtgttcaaac ggctgcttct cggtaataag cccactagcc
    12781 tagaaaatat gaaaagctat tttctaacta gcgttcttat tactcaaagc ataacgctga
    12841 tttcacaacc tcttgataaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa
    12901 cggcaaaaca tgaggaacta tttttccgtt tctttctcta atactcaggt cagaacgctg
    12961 atttcacaac ctctctttca caaccttatt ttactcgttt ataattttca tcgaagtatt
    13021 ttccgctacg gatatcatct ggcattccat cgtatggttc ttcgctaata acatcttcat
    13081 tgtctatacc tgcatcaccc atataagtga tcgtagcaaa ttcaggaaca agtaattttg
    13141 gataagtttc atatttttca cgagctgctt ccatttctgc gatatgttcg ttttggaaag
    13201 taacagtgat ttctggatgt tcttcaaccc atttagggaa aaagatcatt ccgtgaagtt
    13261 tcttttcatt tggcataaag tccaatgcca cgtctgtccc tgttggctct gtccaagtga
    13321 ttttgaatac gccgtccgtc aatttaacga tatcagcttc ttggtctttt acccaacggc
    13381 ctttgaccat tccgccatgg atacggtaat caacagtatg gtcatttttg gcataccatt
    13441 catattccca accattgtca tacgtataga taaagtgagt tccaataaaa tcttccaatt
    13501 ctttaaattc tttcatgttt aagcatctcc ttataaatta aaacatgtaa taaactacat
    13561 gttttcgatt actcatttat gatagaatgg atttaaagat ttgtcaagga gggaaaactg
    13621 atggcaagaa aaaatacact tcgatatatt ttgttagggt tattaagtaa gaagaagatg
    13681 acaggatatg aattgaatca atcgttcaaa aatgaaatag gagaattttg gcaagcaaaa
    13741 catagtcaga tttatcctga acttgcaaaa atggaagagc aaggaatcat tcagcatcaa
    13801 gtagagatca caggtgaaaa attggaaaag aaagtttatg aattaacaga agaagggaag
    13861 gaacaattgg cagagtggat tcatacaccc accaatgaac taccggttaa tcgagacgaa
    13921 tttgttctga aattgtattt cgtcaaagac gtgaatgatc cggcattagt agaaattatt
    13981 cagcagcagc gtgaccttca tgaagaaaaa cgacttcatc tattagagcg aaaaaaaacg
    14041 atctttccta ctgaaaaaga aaaacatgaa aattacggac actacctgat tttagcgcat
    14101 gcgatcaatc gggaaacaga atatgcaaat tggctaacag atgtattaga agaaagtaac
    14161 cgaaaaaaat aaaaaaatat ccgaacagtg atggagaatt cctttctata tgaaagaaac
    14221 gcagatcacc gttcggatat tcttatgttc aaacaggcct tttttcaagt atttatgtag
    14281 catctactta ttaaaaagct tggtacttag gagattagtg gcgtttagag ttcttttaac
    14341 aactgttcgt agtcagcttt ttcatcgaca ggaaggagct tgtaagttaa ttcgtctgtc
    14401 tcgttgtcat gaatgatgta catcttagca ttctcttctt tgaagttacc gatttgtaaa
    14461 atcgtatagc gttcgtcgat caattcgata tctttgattg cttttgaaaa aactttacgg
    14521 acatggtgca ttttcttttg gcggatttct gccttttctg cagcttttga caaagtaaat
    14581 ccgtcatcta aatatttttt gatcagttct acttttatga ctgtaggtaa acgatatttt
    14641 ctaggacaat tcgcatcagc ttcgatcgaa cgaatgaatc ccttttgttc ccaatacctt
    14701 aattgacgtg gagacacacc tacgatatca cttaattcac tgatgccaac aaccaattga
    14761 tcattttcca acaaacgttt aagggaagcc ccaaccattt ttgtcactcc ttttgtcctc
    14821 ttgcttccct taattatatc cgtattaact tatgtgtcaa gtaggttgac aaatagcgaa
    14881 tttaggacta aagtattcta gtagtttcag aaaaaattca gaaagaagga gaaatatgag
    14941 taacaaccaa cccgtagata tttacggaaa accatataat cggacacttt tagttgttgt
    15001 cttattaatt ggtacatttt gtaccgtttt gaatcagacc ttattgacga cagcttttcc
    15061 tacattgatg aaagctttcg atatttcagc gtctgatgtg caatggttaa cgactggttt
    15121 cttgctagtc aacgggatca tgatcccaat aacagcatgg ctgatcaata aattcagttc
    15181 aagaaattta tatctttctg ccatgacgat ctttttgatc ggaacgatta cttgctttac
    15241 agcacctaat tttagtacat tactaatcgg tcgtttgatc caagcttgcg gtgtgggagt
    15301 atcgatgcca ttattgcaaa atatcatgct atctattttc ccgccagaaa aaagaggatc
    15361 agcaatgggg atgtcaggga tcgttattgg acttgctcct gctttaggcc ctacattatc
    15421 tggttatatc attgataact accattggcg tgacttgttt ggtatggtac tgccaatcgt
    15481 tgttcttgtc ttggttttag cattcttcct aatgaaaagt gttattccat tgtcaaatcc
    15541 tagcattgat attttatccg ctattttatc aacgattgga ttcggtagtt tactttacgg
    15601 attttctagt gtaggagatg acggctgggg aagcttgaaa gtaattggtt tcttagttgt
    15661 tggtgtgatt ttcatcgcct tgttctcatg gcgtcaatta catttggaac atccattctt
    15721 ggaacttcgt gtattcaaat catctacatt cacgattgca gctgttttag ctggtgtaac
    15781 aaatatggcg atggtagggg cagaaatggt cgtaccattg tatattcaaa atattcgtgg
    15841 agaatcagca ttccattctg gcttgatgtt gttgccgggt gcattgatca tgggggctat
    15901 gatgcctgtg acgggtgcga ttttcgataa atacggcgcg aaacgtttag ccatcacagg
    15961 gatgttcatt ttgacagcgg caactgcacc atttgctttc ttgacaaaaa cgactccagt
    16021 tttatatatc gtgatccttt atgcgatccg tatgtttggg atctccatgg tcatgatgcc
    16081 ggtaacgact tctggtatga atgcattgcc aaataacttg atcagtcatg ggacagcggt
    16141 aaataataca ttccgtcaaa tcgcaagctc gattggtaca gctattttga tcagtgtgtt
    16201 gacgaatgtg acaaaagcaa atatcccaag caaatctgta ttggataata cgccattagc
    16261 ttataaagat caggcaatca atgccacact gtcaggttac catgccgcgt ttatcgtagc
    16321 gatcatcttt gggattcttg gctttattat tgccttttta ttgaagaaaa aagaacctgt
    16381 tctaatgaaa gcgggggata atgcatgatt attggagttt tgattgtcag cttgcttgct
    16441 tttgctttaa cgaacgtgtt cgctaaaaaa acatggcaaa cctttttatc tttgattttc
    16501 ggactaatct tcgtcgcttc actaagtttg atcgtcgcta atttgtccaa tcactttgga
    16561 atggaaaaag taacggaaac aaaaacagaa aaaattgttt ccagtgctga ttcccaagga
    16621 gcagatatgc ttttgtataa agctttaggg aatggaaaag aaaaagtgta tctttaccga
    16681 acaaatgaaa aacaagaaaa accaaaagca actggtacgg ataacgaaac aaataaagta
    16741 gaaaagacag acggcgatgc tgaaaaagtg acgaaaacta cttattggga atacaaaaac
    16801 gacatgtata aattctggtt caatattgct gataacaatc acgaatatga cagccgagtg
    16861 aatacattca aaatcccaga gacatgggta gaattaagta cggaccaagc agccaagtta
    16921 gctgaattag tgaagaaaca gcaaagtacg atggaaagtg aagcaaaagc ttatgttcaa
    16981 gacggtatgg taaaagcaat gactgaaaat ccaaaaatga gcaaagcaga gcaagaacaa
    17041 cgtacgaaag ccttagctgc tgaattccaa caacaagcat tcgcaaaatt agtgaaagaa
    17101 gcaaaaggcg aataatattt tgaacaccat gtaggaggtt gtgaaaaagc tgctctgcat
    17161 caagcagtaa gaacaatcag ataaaaatag cactccatat ttttcatctg attgggctta
    17221 gtgccgtaga tgcaagcttt tgaacaccgt ttaaggaaga ggttgtgagc ctgccgttta
    17281 actctgagtc acaaggagca atttcaaaaa acagcttctc atgtttgttg actattgtga
    17341 cttgtgaccg aggagttggc aggagaacac cgtttattcg aaaaaaggaa ctgcgacaag
    17401 acttttgtca cagttccttc ttttttttgc tatgctatac tagatgtaaa aaataggaga
    17461 aataaaatga gggaaattta ttcttttgaa tcaaaaatct atgcttccga agtcggcaag
    17521 ggcggggcat atattatttt tccgtatgat ataagaaaag aattcggtgc tggaagagtt
    17581 aaagtccaag caacttttga caatgtgccg tatgaaggca gtatcgtgaa tatgggcgtg
    17641 aaaaatccag atggttcagt ctgctacatc cttggactac gaaaagatat tcgtaaaaac
    17701 atcggaaaag aaatcggtga tattgtagca gttacagtga agcaaaaata aaagaggttg
    17761 tgacaaaaga cgtgtcacaa cctcttgata aacggtgttc aaaagccagt ttctcggtag
    17821 taagtcaaat ttatgcaaaa atgtggaaac ccatgtttac aaaatttttc ttactactcg
    17881 aaacgaagcg gctttatcac aacctcttga taaacggcgt tcaatcagct gtccctcggt
    17941 attagctcaa aaacggcaaa atatgagaag ctatttttcc atttttttct ctcatactca
    18001 ggtcataacg ctgatttcac aacctcttct ttcataatgg tttttcacca tctttataat
    18061 aaactggttc tttgatatgg aaatctattt tttccaacca atctaaaatc ttgtaaccta
    18121 actcttctga catcggaaaa gaggcgttga tttgtgcatt ggagatatgg tcaacatgga
    18181 taccggaagt gatcgtacaa cttcccggaa cggcagtttt gatgatcaca gctatttttt
    18241 cggctaagac atcgtcttta tggaaccgac catcgtggct agggaaacgt acagtttgca
    18301 tctctgtatc acgagaaaat gtagtgactg ttccgatatg tggtgtatct ccgcctgtta
    18361 aagtgatcaa taagtcttta ccgattactt taacagcagc ttggatcgtg aaacctagtt
    18421 tggttacttc aactatcgtt tctttttcca tattaatcac cctgccaacg ttttgaatgc
    18481 tcatttacaa tttcaaattg atccaaaagt ttcattgtat ggtgattaac aagatcttgg
    18541 atcgtttgag gctgattata aaaagcagga attggtggta tgatttgcac acctagtcgt
    18601 gctaatttag tcaagttttc caagtgaatg gcatttaatg gcgtttcacg aggaacaatg
    18661 actaactttc gttgctcctt cattgttaca tcagcagcac gtgcaatcag gttgtcgcct
    18721 aaaccaacag agatacctgc gactgttttc atacttgccg gtacgatgat cattccatcg
    18781 gtcaaaaatg atccgctggc gacagcagca cctaaatctt tgtttgaata atggtaatca
    18841 aacaggcttt cgaattcagt tagtgataag tcggattcca gctttaagtt ctgttttgcc
    18901 catggactga tgattccgtg tgtttctatc atcggatatt cttttagttt cttcactagg
    18961 ttgatggcat aaatggtgcc tgaagcgcca cttacaccaa tcacgatttt tttcttccgt
    19021 tgtgccaatt gttccatttt ccgcactcct ttttatgatg tcaaaacagt tgcagatcat
    19081 tcattatttc aaatattttt cccaatcttc tacttcttgg aattttgcac gtacaaaatg
    19141 ttctttcata tcgaaaggaa ctgtaccgtc aaagatagtt tttgcactta tcccacggaa
    19201 acgaatagag ccaggattat attctggtaa ttctgatggg tccaatggat ggttcctcat
    19261 tcctgggatc acgatgatat ctttatctcc ttggaaacga gtgttgaaag tccaaactac
    19321 atcgttcatg tcgaaaatat caacatcttc atcgactaaa atgactgtct tcaattcttt
    19381 gaaggctgat aaagcaagaa tagctgcttg acgctgaata ccttcatccg cttcgttttc
    19441 tttacggatt tgcatgatgg tcatcaattt accaccacct gcaggaggat tgtagacatt
    19501 tactactttt cctggaatag ctttatcgac caaggcaaga atacttgctt ctgtaggaat
    19561 accggccata gatacgtgtt cttcactggg accaatcgtt gtttgcatga ttggattgtc
    19621 ttttcggtga gtaactgctt tgactttcac tacttgtaca gctggattag catccccagt
    19681 atagccagga aattctggca ttgcttttcc tgagttcgtg ttgatatctt cttgcattgt
    19741 ttcatttggc atgatttctg cttcaatgat gaattcagca cgagcaatac ccacttcatc
    19801 gactgctata ccatcaacga tttgaatagg ttcgttacgc aaagctcctg cacaccatag
    19861 ttcattgtag ccaagtggag tggtaggtgg ttcgaaagtc gtgccaatgg caattgctgg
    19921 atctaaacca atattgatag tgataggcat tggtttattc aaggcttcga attgtttttg
    19981 gaagtgacca atgtggcgtc cgccaggcat gatgtacata ccgatcgtat ctttatcttc
    20041 tagaaccata cgatggatcg ttacatcgct cattgttttt tctggatctg atcctaagac
    20101 tacacccatt gtgatgtatg gaccagcatc ttcaggagta tttgtaggtg caggcaaaat
    20161 gttgcgaata tcgaagtctg catcggtagc tagatgaacg acttcttgtg ctggagcgtc
    20221 tgctttgtct actttcacag gtttgattgg attttctaca gcgtctttca agaaacgacc
    20281 aagtgttcga taatcatggt gcaaaatttc acctacacgt ttacgactag ccattgttcc
    20341 gatgttcaca cgtgtgccgg ggaaaccttt gatattgttg aaagtcatag ctggtccttc
    20401 ttgagtcgga cgttttactg taccgccagc accgatataa cggtaaacac cagataattc
    20461 tgcttcagga tcgatttcaa tatctgtttc gtgatattga cctggaagtg tttttagttc
    20521 ttcgatgact tttcttaaat catacggttg atctgtcatg agagattcct ccttagttgt
    20581 ctttacctat ctatagtaaa aggtgaaaaa gaggaaaaca attcaacttg ttcggtaaag
    20641 tattctacaa tggaatggat gcgttttttt gataatagaa taaactatga tatacttatc
    20701 actaaaagaa agcgcatact tagtgttgga ggaaggaaag tgaaaaaaat ggaggagtca
    20761 tttcctaaag cagtaaaagt ggaaaatata gcgaatattt tgaaagttac atttgaaaac
    20821 ggagaagtaa aatacgtgaa atctcattgg acagaagaga taaccgatgc cttgcaattt
    20881 ggaaaaaaag gaagaggaaa aagaaaaaat cttctcgcac tttctcgtaa tatgtggatt
    20941 gggactgaag taacgattga agcagatgga acagtattca taaatggaaa agacaggtat
    21001 acgccagaag agttgtggta caaaggaaag aaaagtatac cagaattata aaaaataatt
    21061 aaaaaaaaca gcgcgaaaca aggaacatat tacttcctcg tttcttgctg ttttctacta
    21121 tttcagcgct cttatgactc aaatctaaat gtggttgtca caaccttatt ctgcacgcaa
    21181 agcgatagcg gcgtcttttt tcgctgccat tcgtgcagga agatgaccgc caagcatcgt
    21241 caatatagta gagacgatca ctagaataat cgcatggaca ggatttagtt gagcaacatt
    21301 ttttagatcc gtcatgttgt ataagatgct attgataggg aacgtagcta gccatgcaat
    21361 aaacacacct aatatcccag aagaaatacc taaaatacac gtttctgcgt caaatacgcg
    21421 agtgatgtct tttttacgtg cacctaaagc ttttagtaca ccgatttctt ttgtccgttc
    21481 aatcacagat gtataagtaa tgatactgat catgatcata cttgttacta aagagatccc
    21541 tgcaaaagca ataaggacat aagtgatagc atccatcaat ccgccagtca gttcagtcat
    21601 cgttccagct aaatcagtat aaatgatttt atcttcatct gatttgcctt tattgtaatc
    21661 atctagataa tccaagatct tttctttgtc ttcaaaattg ttcggataaa tcatgatact
    21721 tgaaggcaag ctgtctccac ctaaataact aagcaatgtt tgtttggcat tttcgtcaac
    21781 tttttcagta gttaagacat ttacaccact gtctctttga gctttgacga tttctgattc
    21841 tttgttttcg ttgacgattt gagtcgttaa ttgatcgcta taagcgattc ctggagataa
    21901 gagattcatt gtagaagaag atttcacgcg taggatcccc gagatcttca attcatcaga
    21961 agcattctga tacatcgcat cataatctgt attagggata aaattcccag ttggaagttt
    22021 tgtatagtaa gtattgttgt ttactaattt gaatgttgta ccaacgatat catcaaaatc
    22081 aagtttttcg tcttctttca catcaaatcc aagattcttc aatgcgttga tattagtatt
    22141 attattgccg tctacgatca gcacgacatc tgttgctgag gctggataac ttccggcaag
    22201 taaagaataa ttgtctttta aaaagttttc tttgctagtg tcaagctgtg tagggaaact
    22261 tgacactccc acacctgtca ttgctgacat cgtactagat aaagaaagag attccgtatc
    22321 aggattttga ttcgagaagc tgacaggctg tactttgcca tttacatcac gtaaaagatt
    22381 gattcctgta gtacgggtaa atccgatatt attacttaag ttaggatcga tgtctgttac
    22441 gtaatcgacg tatgtttgat caatcttatt cgtgtgctgt gctttatctt cttcgctgac
    22501 ttttgcagta atcgttttgc tgtctggata atccgctttg cttgcaccca atccggcatc
    22561 gtcacgagtc tggttagtcg ttaccttaga aatagtaatc ggaaatttcg ccatcgtttc
    22621 agcttgcgtg ttatcgattt gtttttggaa tccagaagaa agggacagaa cgatcgcgat
    22681 tccgatgatc ccaatactgg aagcaaagga ggtcaagaaa gtacgtcctt tttttgttcg
    22741 gatattgttg aaggaaagct ttaacgctgt ccaaaaactc atctttgttc tgcgtaagtt
    22801 aaattgatca tcttttggtc gttcgatgtg aggatgggaa tctgttaaga tcttaccatc
    22861 agaaaattca atgattcgat ctgcgtattg atgggccagt tcaggattat gtgtgaccat
    22921 gatcactaat ttttctttcg ataactcttg gatcaattcc atgatctgga tacttgtttc
    22981 tgtatctaac gctccggttg gttcatcgca caaaaggata tctgggtcat tggctagtgc
    23041 tcgagcgatg gccactcgct gcatttgtcc accagataac tgatttggct ttttatgcat
    23101 atgatttgtc aagccgactc ggtgcaatgc atcttctgcc cgttttcgtt tttcgtcttt
    23161 agaaacacca cttaatgtca tcccaagttc aacgttttca ataatgccta gatgaccaat
    23221 caagttgtaa ctttgaaaaa tgaaaccgat agagttgttt cggtaggcat cccagtcact
    23281 gtccttaaag tctttagtag actttccgtt gattaccata tcaccggaat cataattatc
    23341 tagtccacca atcacattca gcatagtcgt tttaccagaa ccactaggac ctaaaatcgc
    23401 tacgaattct ttttgtctga aagcgacaga cacaccatcc aatgctttgg tggtggtttc
    23461 gccgacttta taatattttt ttatatcttt taattgaagc ataatcaccc ttctcccgta
    23521 ttgaaatatt cggtatacta ataagtatat cagaacaatg atcgtagtat acgaaataaa
    23581 tgttaactga agatgaacta caagaaaaaa tctagaaatt tttcaaaaaa cagagggaga
    23641 tcaatgaatc gtattttagt agtagaagat gatccgcaat tacagttgct ttaccgttct
    23701 gtgttggaac gagcgggctt ttcagtcatc accgcattga atggagagga tgcgctgaaa
    23761 aaactagaag cgacacgtat agaattaatc attacagata tcatgatgcc gaaaatggat
    23821 ggctatgact tgctagactc attacgtagc accagatttg acacacctgt tctaatgatt
    23881 acggcaaagg ccgattttga ggataagaaa cgcgggttca aattaggagc agatgattat
    23941 atgacaaaac ccatcgatgt caatgagatg atcctacgtg tggaagcatt gcttcgacgt
    24001 tcaaagatca attacagcag tagcttgata atcggacaaa caaaattaga gctagatgct
    24061 tatacagtgt tacaagatca gcattcgttg attctgcctc aaaaagaatt tctgcttctg
    24121 tataaattac tgtcttatcc caacaagatc ttcactcgcc aacagttgat ggatgatatt
    24181 tggggattag atacgaatac agaagaacga acgatcgatg tacatatcaa acgtttaagg
    24241 acccgttttg aaaagacgga agattttcaa atcatcacag tacggggact aggctataag
    24301 gcggttattt aaagatgaaa aaaaagctat tttcacaatt atggatctat tttgctagta
    24361 ttgtcttcat ttcgatctta gtgacactgc tgtgttttct cggttttatt ttcttattgt
    24421 ctcgacattc tatctcgcct gctgaatcgg ctggaaaacc aacgttatac ccgttattcg
    24481 tctttgcggg gttcagtatg gtcgtgggta caggaatatc gatttttgtt gggcggcgta
    24541 tcctgcatcc aatcagtgcg ctagggacaa atatgagtct ggtagcaacg ggagattttt
    24601 cgattcgaat ggatgaacag cagaaagtag cagaagtaca gcaactgtat aaagatttca
    24661 acgttatggt ccaagaactc aatagtatcg agacactgag gaatgacttt gtgtccagtg
    24721 tatcccatga attcaaaaca ccactagcaa caatccaagg atatgttcaa ttgttacaag
    24781 ccccaaatct ctctgacgaa gaacgccaaa tatttttata tcggattatc gaaagtatca
    24841 cgcagctttc acaattaaca gagaacatct taaaattgaa caaactggaa aaccagcgta
    24901 tccaactgga aaagaaagag tatcgattag atgaacaaat cagagaagta atcgtttttt
    24961 ttcagcctaa atgggagaaa gaacagctag aattggatat cgaacttgct gcagtaaatt
    25021 acacaggcaa tgaagagttt ttgtaccaag tgtggctgaa tatcatggat aacgccataa
    25081 agtacaatca aatcaatgga cagattcata tcaaactatt tgagacagcc acagagattg
    25141 tactggaagt gaccgattca ggtgtaggaa tgaatgaaga gaccagagat cgaatgtttg
    25201 aaaaatttta tcaaggagat acaagtcgtc aaatttctgg gaatgggcta ggactttcac
    25261 tggttaaaaa aattctagaa ctgcatgatg gacgtattga ttatagcagt atcgaaggag
    25321 taggaacgac agcaatgata cggttaagta aacaatagga aaaagaataa aacccctaaa
    25381 aattctattg aaggttttta ggggttttta gtcgtttttt tgtgattagg gaaatgttct
    25441 tacggttctt ttggcataaa aatcgctgct ttcttattga actacgagaa atgttagagg
    25501 tgtcattgaa acaaggacat gatgcaagaa agagagcgaa agtcatgcgt cgctctcttt
    25561 ttttgggtgg atagatggac agaaaatgta gggcttagtt ttcttcttga tttaaatact
    25621 cccaaaatgt atctgaagcc aaagaatgct caccgacttt acgagtaaat gcaagataac
    25681 tctctgttgt tggagaaata gggagaatca cagtattttc ttttaataga ttcttgactg
    25741 ttttttccat aacaatagca atccccatgt catttgcaat catattgatg atcaagtcga
    25801 ttcttgctcc tttataagag atttttggtt caaatccagc ttcgcgacac agatctagta
    25861 caggttgata caagttcgta gtggggccaa ggagcaaaaa gttctccttt ttcagttcgc
    25921 ttagatccaa tttcttttta ctagctaaag gatgattttt aggtagaact gctacaaaat
    25981 cgtctgtttc agtaggcaac cactcaatcg aacttggtgg ggcctggaaa cttctagcaa
    26041 agtggatcgt gtcactatgt tcattggcgt cattgtaagt taattcgaca ctttccactt
    26101 ctttcaactg gactgtaaat tcaggatggc gtttcaaaaa ctcggtgatt ttggaaaaac
    26161 ctttataatt gatcattgtc ggtatcgtta agatatttaa tgaaagattg ttgtctttcg
    26221 tataggtttc aagcacttct tgcatagcat ggtattgttc tacgacattt tttacatatg
    26281 ggagcaataa gcttccagct tcggtcaatt cgatttttct atgggcgcgt tcgaataatt
    26341 tgacgtctaa ttctgtttct aacgaaagaa tctgtttaga aatatttcct tgggtggtga
    26401 attgtcgatc agcagttttg gtgaaattca ttgtttcggc taaatcaaga aaaacttcga
    26461 atttatggat atccatcata ttcctcctac ttattccaat aaagaatact ttaacacaaa
    26521 aaatgaattg gtgtaatctt ctctgtctgt tacaatcttt cttgcagcga aagcaataat
    26581 tacagaaatt tttctgattt ttttcgcttc gtagaaaaag agaggagttt tttgatgcca
    26641 actggagttt tgatcaatgt aggttccgtt ttgtttggcg gactaattgg cggattagta
    26701 ggaaataaat taagtgaaca ttttaaagca cagctgacga tggtttttgg tgtgtgttcg
    26761 atggggatgg gaatctattc cattgcgccg atgaaaaata tgccggctgt tatttttgct
    26821 ttagtgatag gaacagcgat tggtttgatt gttcatttag gtaatgggat aaataagggg
    26881 gctgcgctga tgcaagtacc tatttctaaa atcttcccta gtgaaaagct tggtatgacc
    26941 cacgatgaat ttatcagcac attagtgacg gtcattgttc tattttgtgc aagtggtacg
    27001 gggatctatg gaagtttaga ttctgggatg acaggagaca gtacgatttt gatttctaaa
    27061 tctgtccttg attttttcac agcagctatt tttgcgtgta atttagggta tgtcgtttct
    27121 gtgatagcaa ttccccaatt cattattttt tatattttgt tcttattggc aaaatttatt
    27181 tatccattga ctacaccaga catgatctta gattttaaag cttgcggcgg attcttgatg
    27241 gtcgctaccg gttttagaat gatcaacgtg aaaatgttcc cagtagctga catgatacct
    27301 gcaatgatcg ttatcatgcc actgagctgg atgtggacaa attggattat gccactgtta
    27361 taataaaaat caaagagaag ccattttttg ctgactaaaa aggatcaaat cttttagtca
    27421 gtttttttgt atttgacaaa ctgattttga aactatatta tatgttgtat aatatagatt
    27481 gaaataaaat attacacttg agaatagaag gtgacgtaat gcacatccag attccaactg
    27541 ttcttcttga tggtactgtg ctagcagcat taagcaagga agatatgtat gggtatgcct
    27601 taacaaaaat cgtacaagaa agtctctctg tcagtgaatc tacactatat ccggttttga
    27661 gaagattgaa aaaagaagga tatcttgaga cctatgatga accttttgaa ggcagaaacc
    27721 gtcgatatta ctcgttgaca ccaatgggaa gtcgtcattt agaagaaatt attgatgaat
    27781 ggattgtttt tcgagattct ttagaccggt tattggagga gagcacaaat gaatgaatat
    27841 ttgaatgaag ttgtggatca tcttcaagaa attcctgaag acgatcgttt tgatttgatc
    27901 cagtattatg aggaatattt tttagattct ggaaaaacat tagatcagat cattgatgaa
    27961 tatggtacac caaagcagtt tgccttaaaa ttaaaaatca gttacttttc agaagaagaa
    28021 caagcagaaa acgagttagt gaaaaatcca aaaagacaaa ttcgcctgat ttggttaatc
    28081 attatcggtt tatttgcttc tcctgtcctc attccactag cactggggtt tatattggtt
    28141 attgggggac tattggttgc tttactagcg ctcattttta gtatctatgt tttatgtatc
    28201 agtatcttag gtgttggcct attcatgatc atctcaggaa tcagtgtgtt tggacaatcg
    28261 attctgagtg gattattctt tatcggtgtc ggtctgttcg ccacaggaag cgcagtattt
    28321 atttcgccac tgttgctgaa aggaacaaaa gggctttttt atgtcatgat gaactttgtt
    28381 aaatggatgg gacgacgttt tattacaaaa agagatctgc attcagcggg cgtttgaagg
    28441 aggacacata aattgagatt gaaacatttt ttgattaccg gtattggtct gatgcttact
    28501 ggtggcctcc tagcaggtgc aacttataca ttaggcgctc aaaagagtct gacttgggat
    28561 aatggtcctc ggttgatcga tatggttact gagacaaaaa aaatcaagga tgcaaacaaa
    28621 atcgtcatcc atgcagaaaa tcaaacagtt tcggtcatac gcggattgga ttttgagata
    28681 aaaacgactt atgataagac agaaaagcca gaaataaagg agaaaaatgg cgtgttgact
    28741 gtgaatgcag tcaaaaaatc aacaggtgca atcattagtt tagaagacac aagtgcacaa
    28801 atcactattg ttgtccctgc agatcatgaa ttatctgaat tgacaatcga agggaataat
    28861 agtgcaattg atatcaacga agtatcaatc aaaaaagtga atactaagac acatgatggc
    28921 tgggtatcgt tcaatgaatt tacaggagga acaataactg cgaaagatga attaggctca
    28981 cttcgattag atgaggccaa tgtggataac ttgatcgtca caggtgaaaa cagcaacttc
    29041 catctagaag acagtttgat cagcaaagaa ggaaaagtca tcctaaacgg tggcaattta
    29101 tctttgcatg agatggaaaa cagtggctat actatccaaa cgtctggtga atcttatatt
    29161 gaaaaagact accagccaat aacaaatact ttgttagaac aaggacagaa aaagctaaag
    29221 atcactgcta aagacacatc gatcaatatt acgacggatc aagaggacaa tgaaacagat
    29281 tgatcctgta ctcaactgga tattttaaga aaaaacagca aagatccttc caatctttgc
    29341 tgtttttcat cgcttaacgc acataactat agtaaaataa gaaagaaaat atctaaaaag
    29401 aaaacagggt gaaagagtat atgaaggtag aagaaggtca aagagaaaag ttaaaaacag
    29461 aaatggaaag attacatact tatatcactc aactaagcca aaccttctat gatccagaca
    29521 aagaaaaagt gatggttaat tacccgaaca attcagaagg tcgccaatta gagcaagtgt
    29581 accatgaagt tttcaaacat ttattgacgg tgaagaaaga gctggattat tattctttac
    29641 cgattatcga tacaggaata ttgaagtatg atgggaagaa ggaacgattt atctttaaat
    29701 ctgttcggga agatttgcct ctttcagcag ggatggatct agaggtcttg gtagaagact
    29761 attttacaga agaaaagcac tgggttcgaa caaaattgga ttatttaccg caggcagccg
    29821 gagggacaca ggcaagcggt tggtacatca ctgaagacaa agagttagaa ctagaaggtg
    29881 taatggcgcg tattcgaaaa aaaaattaaa aaagtaacat tagatattta ttgaaggata
    29941 aaggagcgca ggaagtagca tgagagaaaa aagagcattt tatatcaatg gttatgcagg
    30001 gattgtcgga ttggtcgtat tagctttagt tggattgttt ttcttctatt taggtatgtg
    30061 gcaagcgaaa gtttgggcac tttttttaag tatttttctt tggttgatca cgttattgtt
    30121 gttaagttcg gcaactgtag tcagtcctaa tcaagcaaaa gtaattttgt tttttggaca
    30181 atatttaggt acgattcgag aaaatggctt tttccttacg atacctttgg cacaaaaaat
    30241 gactgtttcg ttgaaagttc ggaatttcaa tagttctgtt ttaaaagtca atgatttgga
    30301 tggaaacccc atcgaaatct cagcagtagt agtctttaaa gtcgttgata cagcaaaggc
    30361 attattcgat gtagcgtatt atcaagattt tgtagaaatc caaagtgaga cagccattcg
    30421 gcatatcgct agccaatacc cgtatgatac attcaatgag aatgatttga cgcttcgagg
    30481 aaacacgacg gcagtgtctg acgagttgca aaaagagctg caagagcgtt tagcagtagc
    30541 aggtgtcgaa gtaatcgaaa cacgcttgaa ccatttagcc tatgcaacag aaatcgctag
    30601 tgccatgctc caacgtcaac aagcaaaagc cattttgtct gctcgacaaa ccattgttga
    30661 aggagctgtc acaatcactc aaatggcctt agagcaaatc gaagatggac aagaaatcaa
    30721 tttcaccgat gatcggaaag tccaattgat caataattta cttgtctcaa tcattacaga
    30781 caaaggaacg caacctgtta tcaatacagg cgacatgaaa gaccgtaagt gacatacttt
    30841 ttgtaagata ggaagaagga gtttaggacg gattattgtc ttgaactctt tttttagttg
    30901 ttttaaagaa aatgacaaaa ttgaaagaag aatgatagtt gattcgaagg cagaattgtt
    30961 cgcttttttc tataatcagt atataaagta agagagaagg ggaaaaagtg aaaaaacttc
    31021 tgatcggtct acttgttttc atcgttgtgg tacttgcagg ggtgaaaatc gcagattacg
    31081 tagttatggg tggagaagaa tactatgtac aaattacgac agatggtaca aaaacagttt
    31141 caaaatcaga ctctggacaa gaaacagtca actatagata tatcctgcct ggctatacga
    31201 aagagggtaa ggaaaaagaa ctggacttca agggacaatt gactcgaccg cttcgtaaag
    31261 gagcatattt aaaaatcacc tggaacaaaa ataaaggtgt cacttcgtat gaagaagtcg
    31321 aaaaaaaaga cgtgccgaaa acagcactgg aaaaactaat taaagggtag ggaaagaaat
    31381 gaacaaaata gtcgaagtac agaatgtaac aaaagtatac ggaaaaaaca atgagaaaaa
    31441 gacgcaagca ttaagcggca tcagcttcga tgtagaaaaa ggcgaattta ttgggatcat
    31501 gggcgcttct ggttctggta agtcgacact tttgaatatt ttatccacat tagataaacc
    31561 aacagatggg catatccgaa tcaatcaaaa agatgtgacc acattaaaag gaaatcaact
    31621 agcagatttt cgtgcgaatg agattggctt tattttccaa gatttcaatt tattagaaag
    31681 cttgacagca caagaaaata tcgctgttcc tctttcttta caaggcgtca gaccaaaaga
    31741 aatcaagcaa cgtgtccaaa aaattgcaga acgtttatcc atctctcata ttttggaaag
    31801 ctatccttct gagatttccg gtggacaaaa acaacgggtc gccgccgcac gtgcattgat
    31861 cacacaacca acgattctat taggggatga gcctacaggt gcgctggatt ccaaaagtgc
    31921 ccgggatctt ttagatacga tggacgaatt gaatacaaaa gatcatgtat cgattcttct
    31981 tgtgacgcat gatccgtttt ctgcaagtta ttgccaacgt attttattca tcaaggatgt
    32041 cggtatccat caagaagtga aacgtggaga tcaaagccgt gattccttct atcgagaaat
    32101 actatctatt cttggaaact tggaacagta gggggagatt gactatgctt tggaaattat
    32161 cacttactgg gatcaagagc cgtttaagag actacttggt gttattctca ggattagtta
    32221 tggcatctgc tattttttac atgtttgaat caatggcaag caacgaagct tttttgaaaa
    32281 gtaatacgat cgttgcggct acagttatca ttttccgatt cggttctgtt ttactaggga
    32341 tcatcacatt cgtttatatt ttatatgcaa attccttttt gatgacgatg cggcaaaaag
    32401 actatgcaat gtttatgatg ctgggagcaa aaggcagaaa aatcgcacag atgatttttt
    32461 ctgaaacatt cttagtaggg atcgcagcta ctttagtggg ttcagctgtc ggtgtaggat
    32521 tgacaagtat cgtccaccga ttattagtgg atcagttaga tctcaatatt tcgcatttta
    32581 caccttttag tattcacggg ttgttgatca ctgttttgtt ttttgctgtt ttgtttttat
    32641 tagctgctgt tgtcaatgct ttttcgattg tcaaaaaacc gattttagca ttgattcgtg
    32701 cggatcagac accaacaaga atcaagcagc ataaattctt gtttttcctt gaagtagtac
    32761 tgggaattgc ttttctaggc tgcggttact atatgatgaa acacgtgggg acctatcaag
    32821 tctttggtat aggggtagcc ttagttacga tcgtattagg aacttatttc attttccatt
    32881 ctgtgatcat tttcttttta tcattactaa agaaatcaga acagatttca ttgaaaaaat
    32941 tgaacaattt cacattgtca cagttaaact ttcgtattcg tgaatataca caaatgctct
    33001 caatggtcgc tatgctgttt gccttggcac tgggcgcttt gacggtagga ttaggtttta
    33061 aaaatgaaat tgcagacttg acagaaaaca attctggata tgatctagtg atgaataatc
    33121 ctcgggcaga agatcagcaa aaaatcaaag aactttcacc aacactttct gcttcttata
    33181 ctcaaaaaga agatgcggga acgatttact ataatgcaag tgaatttgcg gctcaaccat
    33241 tgatcatgat aaaacatgaa gatggaacac cgccgaagat cacgaaagaa aaagttcctg
    33301 ctaaaaaaat gaatgaactg actgtacaag aggaacttcg aagctatgaa ttgccggaac
    33361 agcaagaaaa agaaatcaag gtagtcagtc aatcagaatt tgatcaactg aacttgccac
    33421 aatccacttt acagctagtt caggtaaaag acttccaagc aaacctgaaa ccaatcgaaa
    33481 cacttgttgc tcaaaataaa atgaacaatc catctttgca aaaagtagag tacagcaacc
    33541 agaaatatga aatgtatgaa gtgtataatg gtctattctc tggttttgaa tttatgggat
    33601 tcttcctagg tttagctttc ttgaccatgc ttgctagctg tttgatgttc aagatcttgt
    33661 caggaagcaa gagtgacatt gctcgttatg aaatgcttga aaagatagga acacgacgcg
    33721 ggttgcttaa acaatcgatc cgtagagaag taggcgtgtt attcttagca ccaggaatct
    33781 taggtgtagt ccatgtctta ttcggattac aaatgtttgg tctattcatg caaaatccat
    33841 acaaagatat ttgggttccg tttacgatat tcttcgtatt gtatttcatc tactatgtac
    33901 tgacgacatg gttatatact ggaatcgtat tgaaaaagag attgtgaaaa agctgtcctg
    33961 catcaagtaa taagaacagc caagcaaaaa tagctcctca tatttttcgt ttggttgggc
    34021 ttattaccgc agatgcaagc ttttgaacac cgtttgttcg gaaaaagagg ttgtgacaat
    34081 atttttgtca caaccttttt ttcacggtct tttattagaa tatagtaaat tttttctcgt
    34141 tactcacgga ataagctgtt aagaaaacgg tttccatgta tactggaatc agtgcaaatg
    34201 aaagaaaaga gggtgcaagg aacatggaaa tcaatgaaca aaattttggc gaaaactatc
    34261 acttgattac gatcacgaat caaaatggga catctttgtc tgtcagtgat cttggggcac
    34321 gggttgttca ttttcaaaca ataatcgata atgaaaaacg agagttgatc ttaggttttg
    34381 atgaagcaaa agaatatcta gaaaaagacc cttatatcgg tgcttcaatc ggacgtatgg
    34441 ctggacggat tacgaatggc acattcaaat tagatgatga aacgttcgaa gtaaaaacag
    34501 acccggacac tggtcattgt ttacatggtg gtgcacctag ctttgaagcc aagcagtggc
    34561 attatacagt catcaatggt gaaaacgaag catcggtcat tttctatcag actagcccag
    34621 atatggaaaa cggatttcct ggaactttag atgtagaagt acggtatacg ctgacgaacg
    34681 atgatacatg gcgagtgacg gtccaaggga tcagtgaccg caaaacagta ttcaatccta
    34741 caaatcatgt ctatttcaat ttaaccggtg atccagcaca gtcaatcgac gaacatatac
    34801 tttggttgaa tagccgatta tttgctacgc tcaataaaga tacaacgcct acaggagaag
    34861 tagtttcagt aagtggcaca gcatttgact tccaacgtcc taaaaaatta ggtgaggtct
    34921 ttgccagtga ttttcgccaa tcaatgatag tgggcggcat cgatcatcca tttttgttga
    34981 aaaaacaatc tggtttacta aatgctgcgg aattgacaag cccagatgaa aaagtatcga
    35041 tccaagtaaa aacagatgct tcaggaatcg tgatttttac agcaaatttt ggagaagatg
    35101 gaccggaaat gcgcgggaat aaattagtaa atcatggcgg tatcacattt gagactcaag
    35161 aactgccagg agcggagcga cttgaaagtt ttggagatgt cactctggaa cctaaccaag
    35221 tacgcgagtt tgtaacggaa tacaaaataa atataaagaa atagaataaa ttaaaaaggg
    35281 agtgtgacag tgtcacatcc cctttttaat ttattctatt tctttaaagg cagatcaagc
    35341 cagaatgatt tgtctaaact taacaaggtt agtacaggaa cagttgcagc tttaactgta
    35401 cgagtagttg tttctggtat ctgtcttgcc gtaaaattgt tccacaaatc ccagattgaa
    35461 gcgacacgga agatggaaga agcgttgttg acgcgtttta tcgttgaaaa ttctaatcct
    35521 gtgattggca cgccatctgt tgtccatttg attggcacat cgaatcgctt agacatattg
    35581 aggatttcag cgtttgcttc ttcagttgtt gctgcttctt ttttcggttc atcatatttt
    35641 gtcaggtcgt acgcttcgat gatcgcgttc aatttttgtg aatattggcg atctgtagca
    35701 taacgtcctt ccaaatattt ggttgcttct ttgtagtctt ttgtttccga cttccaagtt
    35761 ggtttgtaga aatcaggatt gccagtcagt ccatttttga tcaagtcggc atagtcttcc
    35821 aaactttcct tgtaagaagg atatttacgg aattgtgcgc ggatttggta gctttgtccg
    35881 gaactatctt gttcaagtgt attgaaggtc acgctgcttc ctttatatga tcctttgata
    35941 ccaaaaaggt tatgatttgg ttcgcttgat aataagctgt ttccagatcc actttcaagg
    36001 atagcttgag ccatcatgac tgatgcgtag attccttctt tttgcccgat ttcctgtgca
    36061 tcatctgcaa tctttttcaa gaactgatca gttgtttggt tttgactgaa atggaacgag
    36121 ccatctaatc catctaaaat agatgagccg cctgtcagcg aacctgaagc agcaggtaaa
    36181 cctgctaagt ttactcggac agcaaaatca ggcgtgaaat ctgaaataga agttactcga
    36241 actttatctc ctggttgagg cgcatggata aattgtccgt tcccaatata gatacctaca
    36301 tggtgagtaa caccggaaga aggtccccag aagacgaggt cgccaggttg ggcctgactt
    36361 actggaatct gcgtacctgc atattgctgt tcgcctgtcc agccaccgat ataatgaccg
    36421 gttgctttca tatatacgta ataagtcaaa ccagaacagt caaaagtatt tggacctttt
    36481 gctccccata catatggttt tccaagatgc ttgaatgctt ctcgaacgat tgcttgttgg
    36541 acattcgttg tatttgtagg caatacagca tcaattggtg attttacaac aaaatcagaa
    36601 gaagcagaag atggattctc tataccgctt tgatttgctg tatttggacg agatgaagca
    36661 ttgttcgttc cgccattcga tgaaccattg tttggatggt ttggttctct ctgagtattt
    36721 ccattgttat tcgatccaga tgggtttgtt tgattcgaag aattcccgct gttcgaatta
    36781 ttgttattat tgtttgaatt atttgaacca ttattattgt tgttattacc cacatctggt
    36841 ttgtttggcg tttccggatc tggtgtacta gggacttctt cactaggatc agttggtttc
    36901 tctgttgaag tatccggtcc agctttaaat tctgcagtaa tagataaatt gttcgtacct
    36961 actgtaaagg tctttgcatc ataatttact tctttggcac cattaacagc gactgaagca
    37021 atttgttcac cttcagctgg cgtaatagtg taagttacct tcgtttccgc taataaacct
    37081 tctaccgttc cactttccgt aatatccaaa ggttgctgtt caggggaatc cgctgtcgaa
    37141 gcagtcagtt ggatcttacc aatcaaagaa ggagcaattg taagggaata tgtctcggct
    37201 ggcttttcat tttctgatgg atcagccgga tcaatttcag ttggctcggt cgatcctgtt
    37261 gttgagttag ttgttccagt tgggtcttct gtaaaagaat ccgttgtttc actagtagct
    37321 gagctggatg tagtcgtatc tgttgtgact gtttgatcag ctatttgatt atctacggca
    37381 aatacggtat tggtcgacaa aacagacgga gcaatcagcc aagtagcagc tagcaaacgt
    37441 atcgtttttt tatttttcat aataaactag tccttttcct ttcattgatt ttctgtctta
    37501 ttcagcattc attagacatt ttttggaaca gataatcgtg tcgaaaagct ttttcttttc
    37561 ataaatctgt ctgtgtattc taaataaaac aatttgtaaa taagcaacga gcattcattc
    37621 gtttttcttt gacgttcatt ttattgcata gaccaccttt gtttggggat aaacaagtgg
    37681 ggataaaaat ggttatgcat atgtaaatta taccaaagtt tggaaagtat cacaaaaatt
    37741 tataaaaata atgatcctaa aaagaaaaag actgaaatat gtgataaaca tctcatactt
    37801 cagtcttttt cattaactat tcataagaca ttaggtcttc atcaaacccg ctaacgagag
    37861 tagtgatcat tgctacgact agactaacag ccagtcctgc taagtaccag aaaaaagtac
    37921 cggaaatgaa tgcaggcaat gtggtcagac taccaaatac aaaagcgatc gctttcactt
    37981 gggcaaatcc cattacagct ccaccagcag ctgcaccaat gcaagcagca acaaatggtt
    38041 ttttcaatgg gatcgcaatt ccgtaaacag ttggttcggt cactcccgca agtaaaatcg
    38101 aagcaaaagc agaaccggag atcgaacggg tttttgaacg tttacttcgc agaaatacac
    38161 ctaaagctgc accagccatt ccaaaattgg ctgctcctgt caacggaacg attcggtcga
    38221 acccataagc agagatatta ctgatcatga cagggtttac agcccattgg ataccaaata
    38281 ttaccaaaat attccaacca ccagcgatga ttgcgccact gatcggtccg ttaatatcca
    38341 tcatccaagt aattgcggca gctaaacctt cgccaaggta aacacccgca ggcccgaata
    38401 ccattaacgt caaaggaacc gtgataacta atgaaagtaa aggtacaaat actaattgca
    38461 tattttcgcg aatatatttt ttgaggaatt tttcaacaaa agaataaaag aaaataccta
    38521 aaatcgccgg catgacagta gacgtatact gcatcagtac tacaggaatc cccagaaaat
    38581 cagtagctgc tttgccactg tctgaaagta aagaggtcag attcggttca atcagtgctg
    38641 cagcaatgac agccgcaata tatccattca ctttaaacgt tttggcagca gaaaaagcaa
    38701 gaaagattgg cagaaaataa aagacggcat tcgacgcagc agacaaaata tgataagttc
    38761 cgcttgtttc actaagccag ccaatcgtag tcgctaaaac aaccagacct tttaatatac
    38821 cagaaccggc aaacagcgga atgatcggcg taaagatttc cgatatcaaa ccaaatagtt
    38881 tttcgatcgg atttagcttt tctttcggag ctgaatgatc gatttgacgc gtcaattcct
    38941 tgtaagcagg agccaatccc tgatccatga ttatttctgc atatctatcg agtaaaatga
    39001 aatacttaat ggaagggatt tgctgtttta atttttctgc attggctact ggctgttttt
    39061 tcaatttgat acgaagccga gtcgcacatg gaaggacaga atcaatattg tcttttcctc
    39121 ccaactgttc aatcagcata tgaatctgct cggacagtac catctgttca ggattcattg
    39181 tcgtttccat tagaagacca ctccactcac taatataata ttggcgtaag gtgtcatttc
    39241 gcctgtacga ataaatgcat gacagttatt caactctttt ttcatttctt catgtgggat
    39301 aaagctaatc ggtgtatctg gtaacaataa tttgattttt tccaatattt ccgggttcat
    39361 tgtctttatt tcttccgcca attcaatcga ttgtacctca agttcttcta aaacgttttc
    39421 taaaacagat aaaaaacttg gaagaccgtt tgagacagcc aaatctattt tttcagtacc
    39481 aaaggggaca ggcatgcctg catccccgat acttaattta tcaaagtgcc ccatttgtgc
    39541 gattactcgt gaaatatctg aattgattac ttttcctttt ttcatgtttg tttcttcctc
    39601 tcattgttaa ttttagactg ctgattgttc taaagcttcg cggtaaggga tagaaggttg
    39661 cgcaccataa gactgcacag caacagaaga ggctagattt ccataaagga tcgcttcttt
    39721 caagttacta aggtctggct gaagtgtgct gcttaatgcg ccaataaatg tatcacctgc
    39781 ggctgttgtg tcaacggcat ccactttaaa agcagggacg ataccgtgtt ctttttctgt
    39841 atgatagaaa gcgccggcac tgcctagtgt aatgattact gttccaatac ctaattcatg
    39901 gagtttttcg gctgctgcga ccaaactgtt atgatctgtc actctgattc ctgtaatgat
    39961 ttctgtttct gtttcatttg gtataatgat atctgtcttt tcaagtagtt cagtaggaat
    40021 cgtttcacga gctggtgcag gattcaggat cgttgttttt cctgcgtctt ttgcaataga
    40081 aaaagctagg atcgtcgcat ctaagctact ttcaaactga gcaataataa agtcactgtt
    40141 tgtaatcagt tgcttgtttt ttaggacttc ttgttcatgg aaagcattat ttgcccctgc
    40201 atggatcaag atactatttt ctcctgctgc gtctaccata atcattgctt gtccggttgt
    40261 ggcgccttgg atttcagcta tcccagatgt atcgatgttt tcttttgtca gtagatctaa
    40321 taactgttgt ccttcgctgt cagccccaac gcctccaata aaagatgtcc gtgcgcctga
    40381 acgtttggct gccactgctt ggttggcacc tttacctccg ccagcgtgaa aaatctcatg
    40441 cgcatgcatc gtttcgcctg gcttgggcat gttggttaaa cgaagggtag tgtccatatt
    40501 aatacttcca attactgtaa ccgtgttcat tttacaaacc tccaactatc tcatttattt
    40561 tgatgggaaa attatttttt aaaacgtttt agtaaaacgt tttaatagtt cgataaaaat
    40621 atagcacacc ttgaaagcta tttcaagggt gcagttgaaa atcttttttc taatcgtaca
    40681 ggtaatcttt tttcttccca ttctttttct gggaattgga tccgatctaa caataacttg
    40741 gcagatgttt gtcccaattc gaagattggt tgtgcgatcg ttgtcagttt cggcttgata
    40801 tactcgcaca tatctatatt atcatagcca ataatgctgt agtcttcagg gatgcttttt
    40861 ccagcttcct ctaatccgcg atataatcca aaagctaatt catcatttaa agcaaacaca
    40921 ccagttgcag cagaatcaag aagttctgct gtgatctggt agccaccttg ttttgagaac
    40981 tgtgtaggta agaggatcag ttggtcgtga gggatttggt aaacatcaag agcagattta
    41041 aacccctcaa tccgagcgtg gacattttcc ggtggatttt caggatagac aagggcgatc
    41101 gtttgatgtc ctagactaag caagtgcatg cccgctaggt aaccaccgcg aaaatcgtct
    41161 gttcgtacgg catcactaaa tccttcagat tttttctgat ccaaaacaat gaagggccgg
    41221 ccttgttttt tcaaattttc gttgattgca tctgtagaga cagcagaagt cgcgataatg
    41281 aatccatcca cacctcgacg tgtgagctcg gctagatatt cgatttcttt ttgatgatca
    41341 gaatcagcat tacataatat cgtgacgaaa ttctgcttat acaagatatc ctcaattcct
    41401 cgcatcagtg tactgaagaa tggattcgtg atatcaggaa cgagtacacc aattgttttc
    41461 gtttccttgg taatcatttg tctagcaaaa tagtcaggct gatagcctaa ttcttctttg
    41521 gcagctaaaa ctttctgaac agttttcgga ctgaatttct ccgtatttcc atttaatatc
    41581 aaggagacag ttgtgattga aacgccggaa agtttagcga cttctttgat tgtgatcttt
    41641 tttttcacca tgttcatact cctatctaaa tcctgtggtt attttcccat gaaatcaaaa
    41701 agaagtaaat gaaaatcacg tgtgccagta cttatttgct ttgttggata gcttcgatta
    41761 tttgtttcgt tgagcgtact cgtgcagttt tcggaaatat cttttttatg aacaattgat
    41821 gggattcttt gtcacgatca ctgcaagcat cttcagcaag cacgatatgg tacccgtgtt
    41881 gaaaggcatc taatgcagta gcatatacac cgtttgttgt cgctacaccg cttaaaatga
    41941 tagtttcgat tccacgccgg cgaagttgaa gatcaagaga agtaccaaaa aaagcacttg
    42001 gattgtattt tgtgatagtc aacatattat ctgtatcttt caaagaatcc ttcaaaagta
    42061 aatcagtgaa ttctggaggt acagaagcag tcattccacc catatcagtt tgttgactca
    42121 aataagggaa agtggagatg tctacgttca ctaaaacttt caaggcagcg gtacgtttca
    42181 atgttcttac taacaaatca ttgtttgtca gaatagatgc tgcagtgtgt ggagagagtg
    42241 taccgttatt tacgatctct ttttgcatgt cgatcgcgac aaaagcagtt tttgataaat
    42301 caaaaatcat attttccttt aaatcattca tgatgttcct tctttcaaat aacaatgttt
    42361 tttatgtaag taaatcataa atcgtttatt tgtcaactaa attaaaggat tcctttcttt
    42421 agtctagaga aattcagtgg taaaataaat aagtgtgaga aaacgcattc gatgcataga
    42481 tatagcgaga aatatcgtga aaatggagga atcagagtga agtatgtcga agtaaaaaat
    42541 gaatacaaac gatacaaaat gggagaaacg accattacag caaatgacga tatttctttt
    42601 tcaattgaaa aaggcgaatt agtgattata cttggtccaa gtggagcagg aaagtcaacg
    42661 attcttaata ttttaggtgg gatggataca cctgatgaag gtcagatcat tattgatgac
    42721 acagatattg cgcaattttc agataaacag cttactgctt accgacgaac agatgtaggg
    42781 ttcgttttcc aattctacaa tctcgttcct aatctaacag caaaagaaaa tgtggaattg
    42841 gcaacggaag tttctcctga tgcgcttgat cctgtagagg tattgaggca agtgggccta
    42901 gctcatcgat tgaataactt tccgtcccaa ttatcaggag gcgaacagca gagggtttca
    42961 attgctcgtg cactagctaa aaatcccaaa cttcttttat gtgatgaacc gacaggcgcg
    43021 ctggattttg aaacgggcaa gcaagtattg aaattattgc aaaacgctag cagacaacac
    43081 ggcaataccg ttttgatcat tacacataat tctgctttag cgcccatcgc tgatagagtc
    43141 attcacatta atgatgctaa agtaaggtct gttgaattaa atgatcatcc ttcatccatt
    43201 gatgagattg tatggtaggg ggattttatg aaaacaagaa catatcttaa agcaggtttt
    43261 cgcgaaattc ggcaatctaa aggacgattc attgcaatca tccttattgt catgctagga
    43321 acacttttat ttgtaggtgt caaaactgct ggacctgtca tgcaaaaaac gatggatcac
    43381 tatgttggta cagcaggact ttctgatttg caaatcgttt ctactggtgg cttgacacaa
    43441 aaagatattg ctcaagcaga aaagatccca gatgcaaaag tagaaacagg aaaacagatc
    43501 tattattcca atactggcaa aaacgaagtg attcaaatat tttcttataa caaaaataac
    43561 aagcagaaca agctacaatt aactgatgga aaactcccgg aaaaaccaaa ccagcttgta
    43621 ttggatgaaa aagcggaaga tgaagggtat aaaatcggtg atatttatca gattgattca
    43681 gatgaattga aagaaaaaga gtataccatc acgggctttg tccgttctcc attgttcatc
    43741 aacaatttgg agagaggata cgcgaacgtc ggaaatggta gcgtcgatta ttttgtctat
    43801 ttacctgaat ccgtttttaa aacagatatt tattctgtct tatatcttga ttttacaaac
    43861 gtaaagaatt tgaatacgta cagcaaagct tacaaagata aaatggagca aaatcaagaa
    43921 aaggcagaaa agtatttaca agatcgaccc gaagaacgct tagaagagct gaaaaaatcg
    43981 gccaacgaag aattagaacc ggcacagcaa aaaatagcgg atggcaaagc acaaacaacg
    44041 caagcaagaa cacggttaga agatgctaaa aaacagttag cgcaacagtc agcaactatc
    44101 cagcagcttc ctgaagcgca acgaacaatc gctgttcaaa cattatctca acaagaagct
    44161 caacttgctg aacaagaaag gcaattagtt gagaaagaac gtgaactggc ctctgcagag
    44221 gaaggattga atcgaaatgc agaaaaaatt gaaaatttaa ctaaaccatc atacctatac
    44281 aatgaacgtt cagaaaatgt cggttttcaa gaatttggtg atctgtctga tcgtatcgct
    44341 gcgattgcca atgtttttcc tgttttcttt ttctttattg ccgcattgat cacctttacg
    44401 acaatgacac gtatggtaga agaaaaccgc agggaaatcg ggacattaaa ggcgttaggt
    44461 tatacgaaag ttgaaatcgc aaaaaaatat gcaatctatg caagtctagc ctcagggata
    44521 ggtattgttt taggaacgat attaggaacg aatcttttgc caaggatcat ttttgagctg
    44581 tctaacgagc ggtatgatat tgggagtgcg cttatttttt atgactggcc gccgatttta
    44641 caagcagctg ccgcattctt cattgccgca tttggcgctg caatgatcgt tttattcaaa
    44701 gatttaagag aacggcctgc tgcattgctt caaccgaaag caccgaagcc agggaaacgc
    44761 atttttcttg aatacatcac tccgctgtgg tcacgcctta gctttaatca aaaaatcagt
    44821 taccgaaatc tcttccgata taagtcaaga atgcttatgg cgattatcgg aattgctgga
    44881 tgtgccgggc tgatggttgc aggcgtggga ttgaaagatt ctctaagttc tgtttcagcc
    44941 aaacaatttg gaccgatcat tgactatcaa gcaatcgtta cattggattc atccacggaa
    45001 gatagtcgtc aaaaagcagc ggatatgctg cagaagcaag aaaaagtaaa tgagatccta
    45061 gctattcata ctcaaaccgt agaattgaga aaaaaaggac atgcttcgca aagtctgaca
    45121 gtgatcgtac caagtaaaac agctgatttg gatcgtttta tccatttaac tgatcttgaa
    45181 gagaacccac gctccttgcc taaaacagga atcgctatta cgcaaaaagt agcagaacta
    45241 tttgacttat ctacaggaga tcatatttcg ctttatgatg aagatcaaaa agaatggaaa
    45301 gtcgaagtaa aagaaatcgt gaaaaactat ctaggtagct ttatttatat gtcccctgaa
    45361 tattatgctt cagttactga tcaatcgatg atggataatg catttttgct gcgtacagat
    45421 aagatgacaa caaaagaaga agaaatgctt tccgagaaac tgcttgccac agacgctgtg
    45481 acaaatacgt ctttcatgtc caaacaaatc gaaacgcaag aagaatcaat ggcgaactta
    45541 gactcggttg tcttaatctt tgtcgtatta tcaggactgc tggcttttat cgtcttgtat
    45601 aatctaacta atatcaatat ttccgagcgt gtacgcgaat tatctacaat aaaagtcctt
    45661 ggattttttg ataaagaagt cacgatgtac attgttcgag aaaatatcat ctttactctt
    45721 ttaggaatca tcggaggatt tggtgtagga tatatattga ctgacttcat cttgcaacaa
    45781 gcgtctatgg agaatgtcat ctttccatta gtgatcacat ggtgggctta tgtcttatca
    45841 gcaggattaa ctatcgtatt tacggttatt gtgatgattg ttacccattt caaattaaag
    45901 catatcgata tgattgatgc gttgaaatcg aatgaataaa aacagaggtt gtgaaatcag
    45961 cggtttgacc tgagtattag agaaacaaac ggcaaaatag tttttcatat tttgccgttt
    46021 tttgagctaa taccgaagga cagctgattg aacaccatga atcagaggtt gtaaaaaagc
    46081 cgtcctgcat cgagcaaaaa gaatactcaa ataaaattag ctcctcatgt tttacatttg
    46141 agaagactga ttgccgtaga taaaagcttt tgaacaccat ttatagaaga aacaagaata
    46201 ttttgctatt ttaaacaaga ggatagacaa atacatgtct gatctcttgt tttttattgg
    46261 gcaacagacc tcttagaatg tataaagata aattttacaa acgctttcgg ttcagttata
    46321 ataataaatg ataacttgta tatataagtt gtggtaggta ataaatcagt tgaatggagg
    46381 taaatatcca tgacatttaa agacaaagtc atttaccaaa tctatcccaa atcttacaaa
    46441 gacagtaatg gtgatggaat tggagattta aaaggaatca aagaaaaact cccgtatctg
    46501 aatgatctag gcatcgacat gatttggcta aaccctattt atccaagccc tcaaaaagac
    46561 aacggttatg atatctctga ttacacagcc atcgatccta tctttggtac gatggaggaa
    46621 ttcgaacagc taatagccga agcaaagaaa taccggatag aaatcatgct cgatatggtg
    46681 ctgaatcacg tttcgacaga acatgaatgg ttcaaaaaag cactagcagg ggaccagcat
    46741 tatcaggact tcttcatttt aagagaagag ccaacggatt gggtatcaaa atttggtgga
    46801 agtgcttggt cgccatttgg agatacgggg aaatattatt tgcacttata tgatcggaca
    46861 caagctgact tgaactggcg gaaccaagca gtaagagagg aactattcaa agttgttcgt
    46921 ttttggatgg aaaaaggggt aaaaggattc cgtttcgatg ttatcaatgt tatcggtaaa
    46981 gacgaacaat tgaaaaataa taaagaaaat gatggcaaac ctgaatatac ggacaaacca
    47041 atcacccata cgtatctaaa agaattgaac caagcaacgt ttgggacgga ttccactatc
    47101 atcacagtcg gtgaaatgag ctctacgacg atcgaaaatt gtatcttgta tacagaacct
    47161 agtagagaag aattatcaat ggtctttaat ttccatcatt tgaaagtcga ttatgaaaat
    47221 gggaataaat ggtctactcc tccatttgat tttgcagaat taaagcgact atttcataca
    47281 tggggagaaa agatgagtga gggtaacggc tggaatgctc tattttttaa taatcatgat
    47341 cagccacgtg cgctcaatcg atttgtagct atcgatcagt atcgaaaaca aggagcagag
    47401 atgctagcaa ccatgatcca tttgaaccgt gggacgccct atatttatat gggagaagaa
    47461 atcggcatga tcgacccaga ctattcatcg atttccgact atattgacgt agaaagtttg
    47521 aatgcttata agttactcct tgaacaagga ttcacagaaa aagaagcgtt tcgtcggatc
    47581 aaagcaaaat ctcgcgataa ctctcgaaca cccatgcaat ggtcagacac agaacaagca
    47641 ggatttacta cagggaaacc ttggttaaaa gttggaggca agctagaaga gattaatgta
    47701 gaaaaagaac tatcttctga agattctatt ttgtcctatt acaagaaatt gattcggctg
    47761 agaaaaacat atccaatcgt tgcacaagga gattatcatg cttatgaagc aaatcatccg
    47821 gaagtttatg gctttcttcg ccaatttgaa ggacagcagc tgcttgtatt aacaaatttc
    47881 tatgataaag atacaaggat cgccatccca gaaggattca cagaagccaa tattcttatc
    47941 gataattatt ccgatactgt tcttcatcaa agtctggagc taaaaccata ccaggcaatt
    48001 gctttgctga aaaattaaaa caaaaacaca aaacgtcgtt cctacgagct attctcgtaa
    48061 gatcgacgtt ttgtgtttta tttaaaataa tcttcttcag aaaatgaaga gttttcatac
    48121 tctcctttat cgccataaaa tttattgtag cgttgtttga atttacggaa aataaaagta
    48181 acgagtaatt tgactaacgt atagatagga ataccaaaaa taacgcccac aattcccatt
    48241 agatcaccca tgacaagtaa aacgattaag atcgtaatcg gatggatctg taaacgatca
    48301 cccattactc gaggaatcac caagtcaccg tggagaagtt gtacggcaaa ccagacaatg
    48361 acaaatttga cagccataaa agtagagtct tggaatgcaa tgatcaaacc tggaaagaag
    48421 gcgataaacg gcccaatata tggaatgata cataacaacc cagcagaaat agctaaaaca
    48481 ctagcaaatt ctaatccgat cagtaagaaa caaacccagt agactgctcc aaggataaat
    48541 gaagcaatga tttgcccctt tagaaatgaa cccaattgtt gattagcaat ctttgtcaaa
    48601 tttttaaaat ctgtacgaaa tgctggtggg acaatcgcta aaactgactg ataaaatttt
    48661 tgaggatctc tcaaaaggaa aaaagcgaca attggaccag taaataaagt aataaaaata
    48721 gctgtaacag ttgaaaaaat gttgctgatc cgttgtgcgc cactttccca ataatttcca
    48781 ataaatccag ctatatcaga cgtcacgtcg tcaatagaag cgaaaaattg attaaatgaa
    48841 tcggcaaaag gtgttttctc caaaaattgt cggagactct cttgaaaatc ttgaaacaaa
    48901 tctggcaaac tactgatcaa tgtctttgcc tgttcttcaa gaaaaggaat aagccatatg
    48961 cttccaagcc ccaataaaaa taaaataatc acataaacga taatgactga caagttcctc
    49021 gaaaggtgct tgctcaaacg tttgatgact ggttccaaaa gataatacaa gatcagtgca
    49081 aacaataatg ggggcaagat agtagcgata atgattccga caggcttgaa tataaacgag
    49141 atctgatgga aaaaataaat gatcagcgca agtaagataa ctattcctaa aacatagtaa
    49201 gaggtttttc ctcctaaaaa gcggatcaaa cgattcgttg tatctgtttc ttttttcact
    49261 ctttttcctc ctttatctat aaattcatta tagacaaaag cgggtataaa aggaaaatga
    49321 tagaggttga ttgcaaaaat atcgtcaatc attcatataa actttctcat caattaaaat
    49381 aagaaaacgc ttgacagttc ttttaaccat atgataaatt aaatcctgtt gctaaaacgt
    49441 aactattacg gtttgcgaaa agcgaatcgg aacattcaaa tgaaagaaga tgagaagagg
    49501 agtgtcataa atgaaacgat tgataggtat attggccatg ctggttttag caggtatgtt
    49561 aactgcttgc ggggcaagtg ggaaagccga ggacagtaaa gaaaaattga gcgtgatgac
    49621 gaccttttat cccatgtatg attttacaaa agcaatcgtc ggggatgaag gagaagtaga
    49681 gttattgatt ccagcaggga ctgattccca cgattatgaa ccttctgcta aagacatggc
    49741 aaagatccaa gatacagata tctttgttta taatgatgaa aacatggaaa catgggtccc
    49801 cgcaatccaa aaaacattac aagaaggcaa tgtccatacg ataaaagcga cagaaggtat
    49861 gcttttactt ccgggaagtg aagaaggaca tgatcatgac catgaacacg gggaagaagg
    49921 ccatacacat gagctagacc cacatgtatg gctagctcca agtttagcaa tcaagcaggt
    49981 agcaaacata cgtgatcagc tgattgaagc ttacccagaa aaacaggaag tatggacaaa
    50041 aaatgcagca gcctataccg agaaacttca agcactccat cagctttatc aagaaacctt
    50101 taagcaagca aaacaaagat cttttgtcac gcaacatgct gcattcaact atctagcgtt
    50161 agaatatgga ttgaatcaag tatcgattgc tggtctttct tctagtgaag aaccgtctgc
    50221 ggcgagaatt gctgaactga aacactttgt taaagaacat ggaatcaact atatttattt
    50281 tgaagaaaac gccaaagata gtattgccag aacgttagca aacgaagcag gtgtatcttt
    50341 agaagtattg aatcctttgg aaggattgac gaatgaacaa atagaaaatg gagaaaacta
    50401 tctttctatc atggaagcaa acctcgaagc gttgaaaaaa acgacagaga cagaaaaccc
    50461 gctagaagat actttgaccc ccaaaaaaga aaagagcgtc tacaacggtt attttgaaga
    50521 cgaggatgta caagatcgct ctctttcaga ttgggcagga acttggcaaa cagtagatac
    50581 gtatgtagaa gatgggactt ttgatcctgt ttttgaatat aaagaaaaat tgaatcagga
    50641 taagacagca caagaatata aagaatatta tacgaagggc tatcaaacag atattgcttc
    50701 aatcaagatc agtgagaaag agatggcatt tacgtttaag aatggaacaa cgaaacgttc
    50761 aaattatcgt tatgtaggga aagaaatctt gacctacgag gcaggaaacc gtggcgtaag
    50821 gtatctattc gaagcagaag ataaggaaag tggcgctttt agatatattc aattcagtga
    50881 tcacacgatt gcaccggctg actccgaaca ttttcattta tatgcaggaa atgaaagtca
    50941 agaagtattg ctgaaagaaa tggagaattg gccaacattt tatccagata caatggatgg
    51001 acgtgaaatt gcacaggaaa tgcttttgca ctgataggca aaaaagaacc gaagggtttg
    51061 gatcggctgg tcatttagtc ggtccaaact attcggttct ttttatgaaa tcaatttctt
    51121 taatccacgg atagaggctg ggatggtctc gccgtttgcc aacgtgactt ctctggtttt
    51181 tttattaatc gaccgcacat tttgtgtatt gataacatag gatttatgac aacggataaa
    51241 attccgatgc attttctcga tttctttgat cttctcatag aattgtaatt gggcatgagt
    51301 caaatggact tccagtttat gtggcgctcc tagcgaagta gaaaaatatt ggatgtcttt
    51361 gatcggtaaa aatttgatct catcattaaa ctctattttg aagatatctt tttggatttg
    51421 ggacatttga aaatcttcga aaattttgct caggatatgc tcgacatttt cttttaaatc
    51481 ataaagatct tctttgacga tataatcagt cggttcgatg ttgcttttta agattttcat
    51541 cgacatttcc gtatgggaag tcacatagat tatttttcct aaaggatcta attcacggat
    51601 caatttaccg atcgctacac catccatttc actgtcttct agttcgatat ctaaaaagta
    51661 aataccaaaa gaagaagttc tgatcttggc tgcattgaga agttcttccg gatcagaggt
    51721 agaaatatgg acataactgt ctaagttttc aatcatgatt ctatttttga tcaccgttga
    51781 taaaacttct aattgttttg gatcgtcttc acaaatataa atgggaatca tatcattact
    51841 cctttatttt atttgtatat aaatcgtttg agaaaaacgc tggttttcaa ttgatgtttc
    51901 aaggaaaaga taaggattgg tctttgtcaa ttcatccaag ataaacaagc caaggccttc
    51961 gttttttgga tttgtttttg ttgagaaccc tttttgtttc aactggttta acggtaatgt
    52021 atttgttgtt gtattgatca cacgaatcat cacggaatga ttcttcttga gtatggtcaa
    52081 ttcgattttt ttcttctttg cagcactagc tccttcaatc gcattgtcca agataatacc
    52141 aagcatacgt acaaggttta ccgtatgttt cgtatccagt tcgattggct caggaaaatg
    52201 aagctggacg atcaaccctt tttcctgtgc catcatgagt tttaatgaca gtaaactacg
    52261 gatctcagga actttcatat tatccaacat acttagattg gccggaaaaa ggttcatcat
    52321 ctggcgtgta ggtaatatcg tttgatcata ataagaccgt aatccttcta agtcgccttc
    52381 tgaaatatag ctgtgaagag aaaaaagcag attttggtaa tcatgtttga attctctcaa
    52441 gtcttgatag tttttttcta gatctttgat ataatcctgt tgcatcctga cttgttgctc
    52501 taataactga tcagctaatt tcttattaga gattttccaa taataaacca agatgatcag
    52561 gccaacacac agatatagaa tgaaaaaact cgtattcaaa gctaagacat caggtgtttc
    52621 accagaaaaa cgggtataaa aaataatgat atagtatgta aataatatca atgtcccgat
    52681 cgtaccgatc atacggcggt ccacagtgtg aaaccaagtc tctaacgatt tttttaaaca
    52741 aaaagctaat aaagcagata aaaaagcgga taagacaatg tgaaaatact gcaatgaatc
    52801 tcctggttca ataaccgaag atttcaaaac aaaaaaatcg ccgatgcttg ttaagtgatc
    52861 tcctaaaagc gacgtcaata acccaaaagg aagcgcgtaa accaattgtt gacgcgaagt
    52921 cgaaaagaag aaaaaagtaa gcatcagcat tcctatagca attagagcag taaaaatccc
    52981 taaaatcgaa tagacccatc caatcaaaat acaagaaatc agaatgactc ccgcaaacag
    53041 atatttgtat cggatgtgat ggtcaatcaa taagatacaa attgtgtaaa tcaaatattg
    53101 caacgctatg gaccataaaa acataaagta cagctcccat tgatttttac caaattatag
    53161 cacaattggc gtattatttt tttaattttt cagggatttt gaattcagaa ctcataccaa
    53221 agcagcagcc agatacaaaa aagtcagata agttagttaa ttgtttaatg attgtttttt
    53281 tcatgaaaga ttcctccaaa attcatcaag tagtttgtaa taggaagcaa cgtagctatt
    53341 tctaaaacaa tcccaagtag caaataggta gaaaagtaag aagctgagaa aaataacgta
    53401 atgagagaaa aaattagaaa catgctgatc gccttcttta ataatggggg acgtttctcg
    53461 ggttcaatgg gattgattgc tgtacctctt gatccatagc gaagcagtaa caaaaagcag
    53521 ctgattaaca aaaagaccat cattgggaag gagatagtca attgcagatg tttcatcacc
    53581 aagggaacgc cccataaata aagtagtgtc cacagcagac aaacgaattc agagtcggaa
    53641 tgcaatccat aagcatatct gcggatgcag atataagaaa gaaaggtgat tcctgtttcc
    53701 gcccatgagc ctgtcaccag agaaaagact agaacgaccg ctagttttcc aagattattc
    53761 aataaaactt ctaagacaaa ttttacttgg acatacacca tatcttcttc cgatttgtct
    53821 ccgctgaata aggcttctaa taatttgttc acaactttat ctttcatctc atacgtacct
    53881 ccaccacaaa ttttatgcta aaaaaaataa aaaacgtctt ttgtttcata aaaagtggtt
    53941 ttgacatcaa aaccgtcatg atctcctaaa aaaatcttcg ttttccaaga accttaccaa
    54001 aaaaagtgac agttttgata cgaaaagtac tttttatgac aagtttgtgc tttttcgagt
    54061 gatttatgtt aaaaaattac tgaccttata aaaggtgatg gagggattct tatggaaaat
    54121 gaacaattgt ttgaagtcgg cgaaacatat gcatttaaat ctgatttatt tgaatcacca
    54181 ataaaaggaa aaatagaaaa aatctatgaa aatagtgtga tgatacgtgt catgaaatgc
    54241 gcagtagaag acaatgatac cgctcataat ctgcactggc agttagttgt acgcaaatca
    54301 agtacaatag aagaataaaa acagataaaa tgttgagagc ataaagaggt tgtgagtctc
    54361 ccgtttagct ctgagttaca aggaataatg ttaaaaaaca gcttttcatg ttttatgaat
    54421 attgccttgt gaccgaggtg ttggcaggag aatactgttt atttgaaaaa agggctgcga
    54481 caagactttt gtcacagcct ttattttcat gaataggagt tacttttggc tacttttaga
    54541 gaagtagctt ttaaggagca gataaagtca aggcttttat ttctataaat gaagtagtaa
    54601 aatgaagaac agattttatt acaggaagga tgccgataat tgtgatcatt gttgcaggaa
    54661 cgatcggtgc agggaaaagc acactaactg aaatgcttgc ccaagattta gaaacaaaac
    54721 ctttttatga gaacgtggaa gataatgaag tattgccgct attttattct aatccagaaa
    54781 agtatacttt tttattacag attttctttt tgaacaaacg ctttttggca atcaaagatg
    54841 ctttcagcca tgatgacaac gtactagacc gctccatcta cgaagatagt atgctgtttc
    54901 atttgaatgc agatttaggg cgtgtttctg aagtagaagt aaagcagtat gaaggtcttt
    54961 tagaaacgat gctgaaggag ttagaagaaa tttcgccaca aaagaaacca gatctactgg
    55021 tttatattcg tgtatccttt gaaactatgt tagcgagaat caaaaaaaga ggccgggaat
    55081 atgaacagct agaacaagat cctgaactct attcctacta taaagaactc aatcgacgat
    55141 acgaagagtg gtatgaacag tttgatatat gtcccaaaat agtgatcgat ggggacaaat
    55201 atgatttcgt agccgatccg gcatgtggag aacaaatcgt acaagaaatc aagatgcggg
    55261 caaagaaaat gacagaagag gcagatgccc agtcgatccg ctacactaca aataacccga
    55321 aagcaaaggg aatctttaca actaaataat ataaaaacta agcaaattgc tcactcgcag
    55381 atatttctct gtgagcagca tcttgcttag tttttttgat tcattgagat caaatagtga
    55441 accgattcgt atgataaaat tgccataaat gaaatgtctg agtgagggcc atgatcaaaa
    55501 ataaaatgga aacgatcaaa atcgaatggg cgccaaacag atgatgacag aaaacaagga
    55561 caatagctcc tgcgataaag gcaagaacga cacttagata gtggaaaaat cgatcaaaat
    55621 ctgctttttc tttagaaata caataatcat ataagttcgt tgctacccct tttaaatttc
    55681 cagttgtaaa taaattagtg taggcacgcc cgttgatttt atcaaaagct acccactgga
    55741 tcgatgcagt aaaagcaatc aaaatcgtta ctaatgcggg atgctcatgg acgggtgtca
    55801 aactaacaaa gaaaaaaatc actgcttcat aatatagaac aaacaagcgc cagaaatgtt
    55861 tttctttttt tctaaaataa tcaattagat actttgttag aagaatccct aagaaaaaga
    55921 aaagggtaga caatactttt ttaccaacac ttagccattc tccgtcaaat gcttggatga
    55981 tcgatagaat gatattgcca gtttgagcag aggcaaaagc accatattgg atataagtat
    56041 aactgtccat ggctcctccg ataaatgtca gcaaaagtcc tattgtacgc ccctcgtgaa
    56101 aggaagtctg catttttttc atcacctttt atgaatattt ttgtcttcct tatcttagca
    56161 taaacgattg aaaaaaagga aaaattttca gaaaactaaa atcatatcgc ttcccatttt
    56221 catttttaga aaggtctgtt agtataaaga aaaaatagac aacgaaactt taaataacca
    56281 acttgaaata aacaaattca aagaagaaag atgggaagga aatcaatcag ttgaatgaaa
    56341 aagaaattct ccgattacaa aaagaattga aacgctggga gaacaagtat aaaaagcttc
    56401 aacaagtctt tcggctacaa gaagaaatca ttgctaccta tgaagcggct tatggcgaag
    56461 cacccggact tattgaggaa gaagtacaag taaaagaaag tgaaggaaac agctctttct
    56521 ttaaaatgat ggagaaacgt tcctataatc gcttcaatca agaacaaaaa gcagctatca
    56581 catatgatat gaagaaacat cttcgaatca tagcaggagc tgggagcggc aaaacgcaaa
    56641 caatctgtgc aaaagctgtt tatctgatga cgcaaaaaca agtagacgaa gaacgcatac
    56701 taatgatcac ttttacaagg aacgctgcaa atgaactaaa aaaacgagta gataatttca
    56761 gccagagaaa aaccgctgtc catatcggaa cattccatag tatctttttt aggatataca
    56821 atgaaatttg tcgaaaattt cctgaagtag caatgcaagg aatacaagga gacttttcaa
    56881 aggatactgc acaaaaagtg aatgctgttt tgcaacagct gatacgtaaa tataatcttt
    56941 atatatttga tcaatatgga gaaaaaacga ttgcttctcg gttagactat tggcagaata
    57001 tgaacctttc agtagaagaa atggttcagt tagttaaaga aaaatatgat tccattgata
    57061 agaatgcacg acagccgata tcagaacgac tgtatggatt gctcacggaa ctccaagaac
    57121 aaaaaagaag ccagcaattg ctagagttca atgatgtact ccaaaatctg aaaagcgctt
    57181 tggagaatga ggagatccag cattatatcg gccaaaaata tgattatcta ttcattgatg
    57241 aatttcaaga tactaatcca cttcaatggg aaatcgtgaa acggatgaca aaggaaaaca
    57301 ggatcaagtt gattgttgtt ggagatgatg atcagagtat ctatggattc agaggatcag
    57361 agccagcata catcaagaac tttgaaaaag aatatcctac caaaactctt ttcttattaa
    57421 ctaattatcg ttctcgggca gctattgtcc aaggagcaaa tagattgatc agctataata
    57481 aaaatgatcg gataccaaag gcgatgattc cagcacaaaa agaagcaggt gttatggaag
    57541 cctatttgtt ttctgatact aaagcagaaa gtcagtggct aatcaaacaa attcagacat
    57601 ttattcaaaa aaatgggaaa tataaggaat caatcatatt ataccgatca gcttcacaaa
    57661 cgcagcagct tgtccaatct ctgctgaaaa cgaatattcc ttttgtactg gaagcagata
    57721 gtccatatga aggtatcttt ggtatcaagt ctttccaaca tttctatcaa aaaattgttc
    57781 attggcaaac agcactgaat ctgcaaaaga aaaatcaggc ctaccagcaa ttgctccggc
    57841 agctgatggc agactgctac ctgaaaaaaa gtgaatgcga tcaatacttt tctcctaaat
    57901 atcaaaatat agccgttgca gattatattt tgtcgataag ccccaattta aaatcgaaat
    57961 ctgcagaaat ccgagagttt gaggaagcgt tgcgtaaaac agaccagcat caagaaatct
    58021 attcgcttgt tcaaagctat cttcatctgc cacgtatagc taaggaaatc gaccagagtg
    58081 atcaagaatg gatacgagaa gaagtaaagc agcatgctac tttcagaaga ctccaagcct
    58141 tatcgcaaga aacccaagcg acagctaaag aattaaaaac ccgcttgatt gcttacagac
    58201 aaggaaaact tgatgcacta tgtatccaga gcattcacaa aagtaaaggt cttagttacc
    58261 gaaatgtctt tttgattggt tgtaacgaag gaagtttgcc ttataacgga gcgacagaaa
    58321 agaaagtaat cgactttaat gaaataaaag cagaaccagt aacgacgata gaagaagaac
    58381 gaagactatt ttatgttgcg atgactagag caagaaatcg tctgtatcta tgtgtacctc
    58441 aaatgaaaaa ttcaagaaaa ttgaaagtat cgagatttat caaagaaacc gggagtcgtg
    58501 tgaaaaaagg aaagtgatag aagagagggt gtgacagaag tggtcagttt caagaaagaa
    58561 gaaggaatgt acgaaaattg cttctcaaat ttttgtgaaa tttcagctta ttttcgaaga
    58621 agctatttct ggaacacagt ttattcggaa aagggaggtg tgacaagaat tttgtcacac
    58681 ctcccttatt tattttgaaa atgagaatac tattatcaaa atagagaata tatagaaaaa
    58741 ttctcattat tcaaacgtaa ataatcagtt attttgattt tttttatatt ttattagcta
    58801 ataattggta ttttaaaaga aattactgta gaattggatt ataattaaaa aggagtgaga
    58861 aaatgataaa agtatatact tcgcctagct gtacttcctg tagaaaagca agagcatggt
    58921 tgcaagcgaa tcaacttgaa tttgaagaga agaatatttt tgccgaaccg ttaacagaaa
    58981 gtgagatcaa aaagatcttg gcagcgactg aaggaggagt tcaagatatt atttccactc
    59041 ggtcgaaaat ttacgaaaag ctgggcatag attttaacga attaacttta aagcaaatga
    59101 tcgtcttatt caaagaatat ccttcattat tgagacgacc tattttgatt gatgaaaaaa
    59161 gaatactaat cggatttaat gaagatgaga tccggtcatt tgtccctcgt gaaattcgat
    59221 gtgttgccag aaatctgatc tatttacaaa acaataacat cttaaattca tagggaggga
    59281 gccttcgtgg aagtgaaagt ctatggatca gcgcactgtg taacaagtct gaaggcgaaa
    59341 caatggttag aacaccatca attgccttat caatttgttg acttagaaga acgcgatcta
    59401 agtacagaag aagcagaaga attatgcagt tttgaagaag tgcaagcaga acagctattt
    59461 gcgacttggt ctgaggcttt tcacaacatt gcgattgacc tttcctgtgt aggaaaaaaa
    59521 caactgattt ttttatgcac acaacatacc aatctcctca gacgtccttt gattattatc
    59581 gatgaagttc tatttattgg atacaatgag cagttgatgg aacagcttat cttaaataaa
    59641 tagactttaa ctgttttaat caagtcactg agcatttcat acagttgtaa cagtcgaaca
    59701 cttagcatca agcgtgttat gtgttctttt tttgacttta tttttctact atagagacat
    59761 gctcaattta tgtggtcaaa attcaaatct aggtggggat atagagttaa aaatatattg
    59821 acatgtgtaa atttacatga tatattcatt tctgttgttt taagtagcaa agcaataaaa
    59881 tagtatttta aaaaacatat aaaatagttg ttgacatgtt agaaatgaca tgataagata
    59941 actgagttgt taaaaaagaa ccacttgtga agcttgattc tatcgaaaaa aacttcaaaa
    60001 aagttcttga caaataacaa atgataagtt atgataaatg agttgctgta agatttcgaa
    60061 aaacgaaatc aaaaaaactt ttaaaaaaga gttgacaatt acttgtctct ctgatatgat
    60121 ataaaagttg ctacggcagc caaaaacgaa tcggggaaca ctcctgatga agtagacctt
    60181 tgaaaactga acaaagtaag acaaaccaaa tgtgtagggc gtcttgattc aattcaagac
    60241 aacaaacatt ttttaacaag caagcaatat gctagcaaac aaattgagct taacaatcgc
    60301 aagattgttc gaacttttta tgagagtttg atcctggctc aggacgaacg ctggcggcgt
    60361 gcctaataca tgcaagtcga acgcttcttt ttccaccgga gcttgctcca ccggaaaaag
    60421 aggagtggcg aacgggtgag taacacgtgg gtaacctgcc catcagaagg ggataacact
    60481 tggaaacagg tgctaatacc gtataacaat cgaaaccgca tggttttgat tt
//
LOCUS       DAFEKH010000010        59443 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.010, whole genome shotgun sequence.
ACCESSION   DAFEKH010000010
VERSION     DAFEKH010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59443)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59443)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59443
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.010"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(451..1761)
                     /locus_tag="LP386_000708"
     CDS             complement(451..1761)
                     /locus_tag="LP386_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBL1917968.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1773..3191)
                     /locus_tag="LP386_000709"
     CDS             complement(1773..3191)
                     /locus_tag="LP386_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL1917969.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3431..4999)
                     /locus_tag="LP386_000710"
     CDS             complement(3431..4999)
                     /locus_tag="LP386_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBL1917970.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(5003..5413)
                     /locus_tag="LP386_000711"
     CDS             complement(5003..5413)
                     /locus_tag="LP386_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HBL1917971.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5410..6333)
                     /locus_tag="LP386_000712"
     CDS             complement(5410..6333)
                     /locus_tag="LP386_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HBL1917972.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6330..7208)
                     /locus_tag="LP386_000713"
     CDS             complement(6330..7208)
                     /locus_tag="LP386_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HBL1917973.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7195..8532)
                     /locus_tag="LP386_000714"
     CDS             complement(7195..8532)
                     /locus_tag="LP386_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBL1917974.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8535..9638)
                     /locus_tag="LP386_000715"
     CDS             complement(8535..9638)
                     /locus_tag="LP386_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBL1917975.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9712..11220)
                     /locus_tag="LP386_000716"
     CDS             complement(9712..11220)
                     /locus_tag="LP386_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBL1917976.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11186..11878)
                     /locus_tag="LP386_000717"
     CDS             complement(11186..11878)
                     /locus_tag="LP386_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBL1917977.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11900..12874)
                     /locus_tag="LP386_000718"
     CDS             complement(11900..12874)
                     /locus_tag="LP386_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1917978.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13174..14046
                     /locus_tag="LP386_000719"
     CDS             13174..14046
                     /locus_tag="LP386_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL1917979.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14504..16702)
                     /locus_tag="LP386_000720"
     CDS             complement(14504..16702)
                     /locus_tag="LP386_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1917980.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEIEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16934..17926
                     /locus_tag="LP386_000721"
     CDS             16934..17926
                     /locus_tag="LP386_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1917981.1"
                     /translation="MVTIKDVAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17986..19407
                     /locus_tag="LP386_000722"
     CDS             17986..19407
                     /locus_tag="LP386_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HBL1917982.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSLPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19400..20899
                     /locus_tag="LP386_000723"
     CDS             19400..20899
                     /locus_tag="LP386_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HBL1917983.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20938..22332
                     /gene="uxaC"
                     /locus_tag="LP386_000724"
     CDS             20938..22332
                     /gene="uxaC"
                     /locus_tag="LP386_000724"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBL1917984.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22491..23174
                     /locus_tag="LP386_000725"
     CDS             22491..23174
                     /locus_tag="LP386_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HBL1917985.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            23176..24012
                     /locus_tag="LP386_000726"
     CDS             23176..24012
                     /locus_tag="LP386_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBL1917986.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            24023..25777
                     /locus_tag="LP386_000727"
     CDS             24023..25777
                     /locus_tag="LP386_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1917987.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(26053..26394)
                     /locus_tag="LP386_000728"
     CDS             complement(26053..26394)
                     /locus_tag="LP386_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBL1917988.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26462..28633)
                     /locus_tag="LP386_000729"
     CDS             complement(26462..28633)
                     /locus_tag="LP386_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBL1917989.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28802..29701
                     /locus_tag="LP386_000730"
     CDS             28802..29701
                     /locus_tag="LP386_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBL1917990.1"
                     /translation="MVQLVCDCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            complement(29772..30629)
                     /locus_tag="LP386_000731"
     CDS             complement(29772..30629)
                     /locus_tag="LP386_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL1917991.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30614..33316)
                     /locus_tag="LP386_000732"
     CDS             complement(30614..33316)
                     /locus_tag="LP386_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBL1917992.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(33329..34618)
                     /locus_tag="LP386_000733"
     CDS             complement(33329..34618)
                     /locus_tag="LP386_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HBL1917993.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            34768..35814
                     /locus_tag="LP386_000734"
     CDS             34768..35814
                     /locus_tag="LP386_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1917994.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            35816..37969
                     /locus_tag="LP386_000735"
     CDS             35816..37969
                     /locus_tag="LP386_000735"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HBL1917995.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(38442..39893)
                     /locus_tag="LP386_000736"
     CDS             complement(38442..39893)
                     /locus_tag="LP386_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1917996.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(39890..41614)
                     /locus_tag="LP386_000737"
     CDS             complement(39890..41614)
                     /locus_tag="LP386_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBL1917997.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            complement(41607..42221)
                     /locus_tag="LP386_000738"
     CDS             complement(41607..42221)
                     /locus_tag="LP386_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBL1917998.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            complement(42566..44023)
                     /locus_tag="LP386_000739"
     CDS             complement(42566..44023)
                     /locus_tag="LP386_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL1917999.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            complement(44064..44984)
                     /locus_tag="LP386_000740"
     CDS             complement(44064..44984)
                     /locus_tag="LP386_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL1918000.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            complement(44996..45943)
                     /locus_tag="LP386_000741"
     CDS             complement(44996..45943)
                     /locus_tag="LP386_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1918001.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            complement(46422..47141)
                     /locus_tag="LP386_000742"
     CDS             complement(46422..47141)
                     /locus_tag="LP386_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBL1918002.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            complement(47190..48836)
                     /locus_tag="LP386_000743"
     CDS             complement(47190..48836)
                     /locus_tag="LP386_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBL1918003.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            49015..49605
                     /locus_tag="LP386_000744"
     CDS             49015..49605
                     /locus_tag="LP386_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL1918004.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            49697..51202
                     /locus_tag="LP386_000745"
     CDS             49697..51202
                     /locus_tag="LP386_000745"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HBL1918005.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(51286..52638)
                     /gene="celB"
                     /locus_tag="LP386_000746"
     CDS             complement(51286..52638)
                     /gene="celB"
                     /locus_tag="LP386_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBL1918006.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNSSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(52638..53156)
                     /locus_tag="LP386_000747"
     CDS             complement(52638..53156)
                     /locus_tag="LP386_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918007.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(53172..53498)
                     /locus_tag="LP386_000748"
     CDS             complement(53172..53498)
                     /locus_tag="LP386_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HBL1918008.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(53511..55490)
                     /locus_tag="LP386_000749"
     CDS             complement(53511..55490)
                     /locus_tag="LP386_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBL1918009.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(55511..55825)
                     /locus_tag="LP386_000750"
     CDS             complement(55511..55825)
                     /locus_tag="LP386_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HBL1918010.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            55993..56286
                     /locus_tag="LP386_000751"
     CDS             55993..56286
                     /locus_tag="LP386_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HBL1918011.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(56364..57476)
                     /locus_tag="LP386_000752"
     CDS             complement(56364..57476)
                     /locus_tag="LP386_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBL1918012.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            57863..58042
                     /locus_tag="LP386_000753"
     CDS             57863..58042
                     /locus_tag="LP386_000753"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918013.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            58236..58406
                     /locus_tag="LP386_000754"
     CDS             58236..58406
                     /locus_tag="LP386_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1918014.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(58830..>59443)
                     /locus_tag="LP386_000755"
     CDS             complement(58830..>59443)
                     /locus_tag="LP386_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBL1918015.1"
                     /translation="LTTGADGKLAIDGLAPGVYQLVETQAPTGYELDATPIEFEIERS
                     QTAVVELTKENRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKL
                     AIDGLAPGAYQLVETQAPTGYELDATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGN
                     NPTSSGNKHLPKTGETIISQFILSILGVLLVFISIKFRKKRNI"
BASE COUNT        17785 a        12131 c        10390 g        19137 t
ORIGIN      
        1 ttgtcttgaa ttgaatcaag acgccctaca catttggttt gtcttacttt gttcagtttt
       61 caaaggtcta cttcatcgag agtgtttccc gattcatttt tggctgccgt agcaactttt
      121 atatcatatc agagagacaa acgattgtca actctttttt aaaagttttt ttcgatttcg
      181 tttttcgaaa tctttcagca actcatttat cataacttat cgtttgttat ttgtcaagaa
      241 cttttttgaa gtttttttcg atagaatcaa gcttcgcaag tggttctttt taacgactta
      301 gttatcttat cacgtctaaa aacatgtgtc aactcttttt tggaattttc ataaaatgtt
      361 tcaatgaagc gcgacaacgt tgtttaatat atcattaaaa aaaataaagg tcaagctaaa
      421 atattattta agcttgacct tattataatt tcaacgattg tcaaaagtat tgtttgcagc
      481 tgtgttgcca gtttctatag ataaatcaca gcttttgaaa cataagtttt gtactgcttc
      541 gattcgcccg aattcttttg cagttatttg gcaatgagaa aagcagacat cttctatagg
      601 cttttcagga aatgctacta aatcaaaagc tcgggaagga agtgagtaac ctggagaaag
      661 gcatgcctgt acgtttttga tgtgtatgtc tttgactttc gtcatttgct ttgattcagg
      721 tatttcttca gccactgctt gccaactttc tggcatttga gcaaggtcat tgctattttt
      781 tctattgtat tcattatgcc agtccattat ccaagaaaaa ggaaattgta catcaatcat
      841 attcagattt tctaccctga tattttcgat cactccccct ctttcttttg aagatttcat
      901 tcgaatacca cagtctgact gaaaaaaatc gatatcgtga atatatacgt cactaactcc
      961 agcactaact tcgctaccaa tagttacacc gtatcctgaa cggattttac atctagcaac
     1021 ctcgattctt gatgattttc gattgactct tgcaccattg ccatctctgc cagacttaat
     1081 agcaatacaa tcatcaccac aggccaaatc acattcatag acacgcacat ttgttgaaga
     1141 atcaatatca atcccatctg tacttggtcc atcattgttg cggatgatta ctttttctac
     1201 taatacatcg ttagaataag tgatttgcaa gttccaaaaa cctgatttct gaaaaatcaa
     1261 atcacgaaca acaacatgtt ctgcatgata cagtaaacaa gcgcgtggac gtttaatagc
     1321 ataatccgca atccaacgaa gtcccttttg atcgtattca gctcttgtcc cgcttttttg
     1381 atcttttccc caatacagct cccaccaatg gtctccttga ccgtcgatta ttccttttcc
     1441 ttctataaga atatctttcg ccgagagaac attcaaaatc gctgctggcc atttcatttc
     1501 tacgccggct actcgtgtat cgatttctgg aaatgcttcg atatctgttc tccccttgag
     1561 gactgcacct tcttcaaaga taagatgact cttatctttt aaaaaaaggg ctccgactaa
     1621 ataaatgcct tttggaataa atacaggtaa gtgttctttc gcaccttgat cgattgcttt
     1681 ttgcagtatt attgtatcat cttgttgagt gtcgtttgtt ttaaagttca aagcattgat
     1741 aatccctttt tttgtccgca atacgtttct ccctatcttt cattgatttt tttcaattct
     1801 tcaccaataa atacagtttt tgaacgattc agtgggtaac ctactagcaa aatgattgcg
     1861 gatacaaata agcagaatgc tggtaacaag tttgccatcg tataaatcct ttcttgtact
     1921 aaaactgatt ggatggctcc acctgttgta gacgattggt aaccaatgag tgccagcata
     1981 aatccgccta ccgctcctgc acatgcttgt cctacttttc tcgcaaaaga atttactcca
     2041 tatactgttc catcttctct taagcctgtc ttatattgat gataatcaat cacgtcagta
     2101 atgaatgccc agaccatcaa attgaataaa ccagatccta aagtagcgat aaataaaaga
     2161 atcagatata cccatgcatt tgttatatga aggaaataca tcagcaagta catacatgaa
     2221 gaagcaagta acgcaaatac gcttgcttcc tttttaccaa ataattttgt cagctttgta
     2281 gcaaatggtg ctaaaactac tactgttccg taagtaaata aaagagcaac agacattgct
     2341 tgtttattat ggaagtaatc attgaataaa taagtcatat tcgtcccagc taaaatctga
     2401 ttgatcacaa tgaaaatgtc aacaatgact aaaataatca gtgctcgatt agctaacaaa
     2461 ccttttacca actgagaagc agatactttt tcgtttttga caactcttac tctttcagta
     2521 gtcaatttac aagttaacat atatgcgaca aatgctattg cagcacatcc gattgaaatc
     2581 caaaagaaat gattccctga aacgacttgt tgtccactct tgttatgggt atacattaaa
     2641 atcggaatga agaatcctgt agttgatccg ccaatcgcag aaccaatgct tcggaacgtg
     2701 gacaacgagg tgcggtcatt aggatttgag ctaattgctg ctgccattgc tccatacggg
     2761 atattgattg ttgagagaaa aatcccataa acaatgtatg aaacaaaaat ataagcaatc
     2821 ttcaccgtca ttggaagatg ttggacgaat ggcaaaaaca aaatgacagt cactaagcaa
     2881 aatggatact tcatttttct gatccaagga ataaatcggc cagtttctgt taactctgag
     2941 acatcacata atcttccaac catcacatca gcaaacgcat ccaaaattct cgaaatcaag
     3001 aataacgtac ctacgattgc ccctgaaacg ccaagaacat tcgtataata aatcatcaag
     3061 aaactattga ctaaacctaa aataaaacag ttacctagat caccgaacat gtagcctatc
     3121 ttatcggaaa tcccaaattc ctttttttct ttttttattg tatttgctgt aacagcattt
     3181 tgtgaaagca tttgaattcc tcctacctct tctagtaaac gttttcaaaa ttataactct
     3241 ttttttcttg tttttatatt cacaatgttg gctttttatt gcattatctt gacagataaa
     3301 aaacaaaaaa taatctaaaa acattgatgc ataagattga taactttttt tacataacaa
     3361 tatatacaaa caaaaaaatt cactaactag tgaaaataag ttagtgaacc tcatttatta
     3421 aagaattaaa ttacagatga tcttttccat catacttgaa aaactcaaaa tcagcataac
     3481 ttcctctttt tttatttaga tcatgcactg ctatcccgat aaaatttcca gtaaaccctc
     3541 ctgagagtat acacatgttt ttttgcggac ctactttctt ccattcttca gttgatacgt
     3601 ctttcaaatg aaactgtgct gtctctttct ttacagtgac tttcaaaaaa gtcttctttt
     3661 ctgtgagtgg aatcgtccaa tcttctattt gtgctactcc gttttctgat tctatcatac
     3721 gtaggcattt tcccttgtcc tcattccaag taacataaca ataaatataa ttggattcat
     3781 ttaagtacag taccagtcca gccatctgat taaaattatt aggcatgtat tcaaatgctg
     3841 tctccgcatc aaaagtaaaa tccgtttgcc gaatagctaa caaatgatgt tcgaaggtag
     3901 attgaagaga ttcaccggaa atcagacgta aaaaacctgg tctacatttt gtatcacacc
     3961 aatcagcatt tggcaaaatg cgtctggcat tccagttctt ctttagctct ccttcaaatg
     4021 tatccataaa ctgatgatct ttttcttgtt gtacctcttc atttgtctca atcattattt
     4081 cttccatcgg agttgtctgg ctatctttaa gtcttaacca atcgtcggac gtccaataca
     4141 cttcttgaat agcggtttct cttcccaaaa tagccgcacc gtttaatggt ctggtacaaa
     4201 gatatgtcat gtaccatctt cctgacgggg tttgtactaa gctcccatgt cctgtacatt
     4261 gcaatgtaga agcaggtttg tcactagctg tcagcatagg aaaaccagga tcaagctcgt
     4321 aaggaccagt aatattcttt gctcggcaaa ctgtaactga atgtcctctt cctgtaccgc
     4381 cttctgccgt catcaaataa taatacccgt tacgaaaata caaatgtggt gcctccgttt
     4441 tcgctaattc tgtacctgca aatattttat agatgggacc atcaagcttc ttcttctctg
     4501 catcatattc ttgtaatacg ataccgctgg atttattcgg tgtgtccaga cgataatccc
     4561 atagttcatt gacaagccat ttttttcccg tttcaagatc atggaacaaa gaaggatcaa
     4621 agccgttact atttaaataa attggttcgg accaaggacc tgtgatctca gatgcagtga
     4681 tcaaataatt gtggacatct ttaaacggac ggcctgcact tttgacatct gtgtaaacaa
     4741 gataaaacaa tccatcagca taactgatct gtggcgccca tatacttcca tttgtaggat
     4801 ttccttgcaa agatacttga gtggtcaaaa tatccgttgt atgtgaccag ttgactaaat
     4861 ttttcgactc atatactcgg attcctggaa gccattcaaa agaggagaca ataatgtaat
     4921 accgctcttt cactcttaat atattaggat ctggattgaa tcctcttaaa ataggatttt
     4981 tcactttgat agtctgcatg attcaggctc cttttctcat tcttactcga tataaactga
     5041 atgccccagc tgcgaaataa aaaaatgcaa aaggaaacgc aataaactga gtgccaatca
     5101 acaatatgaa tcctgttata aaatacaaac cagtggcagt tgttaagtat tttcctttag
     5161 cagtcaaaaa caatgctact gctaaaaaag caagtgaaat aaacaacaca acggcaaaca
     5221 gaccagtcat gtcctgtaat aatccaaatg tattttctaa agacaaagtt gaatgatcta
     5281 cagcaagcga ctgataactt tttttaaact ctgacgcaga catattactt aaagtaactg
     5341 ctaacccgcc aaagaaaatc aaagatagac tgccaccgac cattcctagc aatagttccc
     5401 attttctttt catttctgaa ccccctgctt ttctaaatgt atccattcag gtcttttgat
     5461 cgatgtttca taattgttat tacgttcaga gaatttgaca gtctgttcat ttttcttgtc
     5521 atcccaatta tcccaaccag ttgggtgaac atgcccacct atcttacacg cttcaaataa
     5581 gacatttgca tacggacgcc acggtcttcc taaatagacg tttctagtat caggttctgc
     5641 agtcaaggta cagctttcaa aacgataccc tgttttttga tttttcggcg tagatgctgc
     5701 tgtgatgtat ccaggatttt tactggctaa gctatggata tgacactgat gaaaaacggc
     5761 atctgcccca ccaaatatga aatccaccgt tccttcaatc cagcaatatt cataggtctg
     5821 acgacaatac tcaggattgg cagaagccgg tgtacaaaaa ggagtaccat ctttttgcaa
     5881 atcaggcaac ggacccgtgc ataaggtatc ctgataacca gatagtcgac agttttttaa
     5941 agatacgcga tctcctgaat tgaataaagc aacagcctgt cctacctttt ctcctggacc
     6001 tgctgtattt tcgatgtgaa gattttctaa tacgacattc gatccttcta agaaaaaagt
     6061 agcacttcgg aaagtcccta actggctacc gtcaagatac tcctgttttg caaaacgatt
     6121 accggagata actactgttc ctgctcccac aagtttaaaa ttggataatc tgctttctat
     6181 atattcatca tatcttcctt cttttactat caagaccttt ggatggctat ccggcaggcc
     6241 tgccaaataa tcgattcctt cttggatagt ttcaaaatcc gtcggggtat ctatagcatt
     6301 ctttccaatt atcagtttgt ctttcatcct cataaatgct cccttatgaa ttgtttccaa
     6361 atatttctca tttcttgtgt ttccatatga ccgcctgtta aagaaaaaga agaaaagttt
     6421 tctggactac ccattgattg atactttttg tccagccctt ttctcagctt cagtacgcct
     6481 tcgtccaagc acatcgtatc gttttttcca actaagctaa gacgagggcg cggagcgatt
     6541 ttttcttgga ttgctaacgt tgtataagct gtcaatagat ttggcacata gtaataaaac
     6601 ccatgatgat ctaggcggcg atgtagcaaa agtatttcga tgtccacctg tgccgctaga
     6661 tcaatacaaa ctttgacacg agaatccaat gctgtcaccc accagcttaa taagcctccc
     6721 atagaaagac caatcgttgc gagccgttga gtatctgtgt cttcccttgt ctccaaataa
     6781 tcgatcaagc tgatcacatc ataaatacgc attccccata acgtttttcc tgttaataaa
     6841 aattgtttga acaactcgct ttcagaaata cctccgcgtt cttcaaatcc ccaagcatca
     6901 atcgaccaaa cagcatatcc cattcctgtc agtacttctg caaaagatgg agaagctaag
     6961 taaggagcac catggatcaa ttcacttttc ccgactgaaa aatctccgcc gtgagaatgc
     7021 aggtaaagga ccggcggaaa cggtccttct ttttctggat aagcatagag ggctggtact
     7081 gtttccaatt catttaagta caattgatag tattcaagca taaaaccgtt ttgtttttct
     7141 cggtataatc gttttccact aggggtatgt ctgctagatg gagcacctaa aaaatcattc
     7201 aactgcataa gcaaagtttt tacgaacaac cagttcatcc atattttctg attgatttga
     7261 ttggaatttc tcaatactga tttctttagt attttctaat agaaatgctg gtccctcgtg
     7321 attttcaatc gacatctggt taaaggaaac cttacccgca aagccaatat aaaatccttg
     7381 tctgctcatt tcctctattc ctgtcatcat agcaggaaca ccgggaactg catcttgggc
     7441 catcgagaca tcgatattgt caaatgtgat ttcttgtatg aattgttccg ctaatccata
     7501 aataaaacct gcagaagcat ggacattcct tgccgtgata ttcgaaaaat ggatccttct
     7561 gaatgctggt gtccgttcat ctatcggata agcctttttt tcccatacat acggttcttt
     7621 ccctcgcgga ccacagaaat aataaagatt cagtataaat ggacacatca cattatccat
     7681 gactatattg gatactcgaa tatcttcaac gatcccgcct cgacctcgtc tagatttcaa
     7741 tcgtattcct cgatcagttt cttggaagat acaatttgaa atggtaatat tacgaatact
     7801 accactcatt tcacttccta atacgacacc gccatgtcca tggaccatcg tgcaatttgt
     7861 gatcgtgata ttttcgcaag cgatcctttc gtacgtatct tcagtccctg ccttgattgc
     7921 aatacagtca tctcccacgt caatatggca attactaata cgcacatttt tgcatgattc
     7981 tggatcaatt ccgtctgtat ttggtgaatc cgctgggttc aagatcgtca agttatcaaa
     8041 cgttgcatta ctgcaaagaa tcgggttgat cgtccaactt ggtgactgga tcaatttaat
     8101 atctttcaca gtaattcgat gacagttatg gaaactcatc aatttaggac gaggataagc
     8161 gagattatct ggttcatttc taaaagtatg ccaccatttt tttccatttc catctaatgt
     8221 accgaaacca gtgacagaga tgttctctac attttgagca tagatacagg aagcataaac
     8281 ttttcgatgg actccttccc aacgtgaatg aacaacagga taatcttttg gatcgtcaga
     8341 gaatttcaga accgctcctg cgcttaaatg aagttcgaca ttgcttttta aaaataaagc
     8401 tcctgttaga aattcacctg ctggaacaac tacggtcccg cctccgtcac ttgctgcagc
     8461 atcaatggct tgttgtattg cttcagtatt caattcatca attgatgcgc caaatgtcaa
     8521 aatatcatac atatttataa tgcctccact tcaatcaatg cttgcaagaa tgcaccaacg
     8581 cctttttgat cattacaaat aattggttca ctgatgtagt aagcatatga accatctcgc
     8641 tgatctgctc cgcctaaccc tgctacttga cagtttttat tcaagttcag ccagccttct
     8701 tttgtttcca gaacaaattc atcaagtaat ccttgatgtg atttcttcac ttgtggaagc
     8761 cattcttctt tgttcagcag tcccaaacgt attcctttag ccattgcgta aacaaacata
     8821 ctactgccgg aagcttccag ataatttcct ttccgttttg tttctgttgt tacttgatac
     8881 catgtcccgc tgttttcttc ttgatatgga agtaatgcag ccagtgtctt ttctagaatt
     8941 tctttcagca aagaacaatc tgtttcttca tgaagtaatt cataggtatc tgctgcagcc
     9001 atcaaatacc agccaatcga tcggctccaa aaatgatggg atagacctgt ttttggatca
     9061 gcccatggtt ggaccttctt ttcatcccat gcatgaatca gcaaatttgt ttttggatcg
     9121 aatagatgtt tataactgat ttcaaactgt ctcaaaacat cttggtaatc tttttcttca
     9181 ctaaaattct ggataaattc agcataaaaa ggagaaccca tatataagcc atccaaccaa
     9241 atttgataag gataaatttc tttatgccaa aaagctcctt cggatgtgcg tggatggttt
     9301 gccaactgct gggaaaggag ttctgctgct tttttatatt tttcttcgcc tgtttctttg
     9361 tacaataaaa agaaaagctt tcctgtattt acatggtcga tattgtattc ttcaacgctg
     9421 tagccacgga tcgttccatc ttcttgcacg aaatagtcga tattgtcttt tatgaaatca
     9481 aaataaattt tttcttgggt tcgttcccaa agtaattgga accctttaag tacgacgcca
     9541 tagtcataag accattttcc tttataccac ttttcttcat ataagcgagg tgttctttcc
     9601 atgatacttt ttgctaattt ctttgaccag ttttccatta tttgctctcc tttaaaaatt
     9661 aaaataggat ttgggacaaa taccaagaag tatttgtccc aatcgtctat attactgtgc
     9721 cgctgctttg tatgcttcct cgtactcttg tgtgattcga tcgcctcctt gtgctttcca
     9781 gtcttctaca gcttttttga atccatcttc gtcaagctgt cccatgatgt attgcaccgt
     9841 agcatcaatg acgatttttt caatttctga tcctacttca ttgttcgtcg gtgaatccaa
     9901 tggcacagaa ggatccatta cagcaaattc ttcattttct ttgatcaatt gattagagaa
     9961 ttctttttca gggtctgtat ctttgaaaga gaacgtcact tcactaggac gagagcttga
    10021 taacggttgc acctcttgtt gccaaagatc catatcgata aattcgatag aaccatcatc
    10081 attcaattca taatgcgttc cttcgatacc gccagtcatc aatttataca catcttcttc
    10141 taaaagatca tcaacaaatt gaagtaattt cttcaattgt gcttcgtctt ttacttgaga
    10201 tttgggaaat gctagcaagc cgccaatacc atttccttct gaccaaacat gataaccgcc
    10261 gccttcacca tctgagatct tgtttacagg cactaattcc atatcatctt gaataccttg
    10321 acccatcgtc ttcagattct tgatatccac cattccagtg tagattccag ttcttccttg
    10381 tgcaaattgt tcttgctgat cagtcttttg ggtaactgca aagtcttgtg ccaaatagcc
    10441 attctcaaat agatctcttg aaaaattcaa agctttcata tactcttctg tatcaaattc
    10501 tggagtgaat ttgccattat cgtctacagc ccagccattt ggtgctccaa aataagaagt
    10561 gaaaagttta aagctggtat aacgaatatc actaggcgca cgatcgccaa aaccaactgt
    10621 gtcgtccaca ccatttccat caggatcgtt ttctgtaaat tgtttagcta cttcataaag
    10681 ctcatccatg gtagttggaa catctagtcc tagattatcc aaccagtctt ttcgaatgac
    10741 taagccagca cgagcgtagt ctttttgtat cggtacgccg tacaaggcac cgtcgatact
    10801 cgcagcttcg attctatctt cagaaatttg acttaaattt ttatagtctt ttaaatattc
    10861 tgatacatcc cagaatacgc ctgattttaa cgcattgcgg acagaagagt ttttcaacat
    10921 cgcaatttga agtgtaacga tatctcctag ttcatcagaa gccaatgcag ttgttaatct
    10981 ttcttctttt gaagcatcag gaatccagtt gaatgtcagt tccgtatcgg ttttttcttc
    11041 gatcaagttc acaatcgtgt ctgtaggcgg tgaagcatga tgcaaaatat ttaaccaagt
    11101 gattttagct tttccatctt ctgtctctga agaactgtta cttgaactgc tgccgcatgc
    11161 ggcaagtgct agaattcctg caaaactaag acctaatttt acgagcgttg cttttttcat
    11221 aaattttctc cttcactgtt ttaataatat ttttgttttc ttctgttttt tctgtatatg
    11281 agttcttcca ttccaaatgg caaaatatag aatttgctgt ccacgtgact gcggaaaaga
    11341 agagactgcc accgataaag gttaaaacac ctggcattgt ttggatgatc atcagataaa
    11401 tccctaccat acttaatatc aacactaatg agtaatgaag atgtgagaat ccgaataaaa
    11461 atgccatttt cattttgaaa aaatatcctt tccaatcata atgagccatg attgggaaaa
    11521 tatagagtgc tgagagcaca tatatgaacg cagcaatata caaagcgatc ctaagatacc
    11581 aattgtgtat gaaagaaaga tccacaagta aaacaatccc gatggcgcca tatatccagc
    11641 tcatcagcaa ggtttcacga tagttttctt taaaatatgt gaagtacgtt ttcgtcaaag
    11701 gaaacgtttc ttttgagcgc agccattttc taatcactgc aaccatcgca tacgatgcag
    11761 gaccgaaagt aaaaactccc aaacctgcga tgactaaacc gccccacaga aaattcaaat
    11821 aaaccaactg taaaatacga tttagccttc cgtttatttt atctaatgac tgcagcatat
    11881 ctttccctct ctttctatct tagtaaacgc cgtcttctcc tagctttttg gcaatcttat
    11941 tagctaaaat taccataaac aatcctacga cccctttaaa caatcccatt gctgtactga
    12001 aacttaactg tccattcttc aatccagctg tataaatata ggtgtcgaaa atttctgcaa
    12061 cgcttcgatt caatgaattc aataacaagt acatatgctc gaaccctaag tctaatgtct
    12121 gaccgatttt tagaatcagc aaggtaatga ttactggacg aattgccggc aatgtaacat
    12181 gccatgtttt gcgtaagcgt cctgctccat ccatttctgc agcttcatac aactgtgtat
    12241 cgactgcagt tatcgctgaa aggtagatga tcgtagacca gcccaactct ttccagatca
    12301 cttgtccgat atatactgtg cgtgtccatt caggggatgt tagaaaactg attttttcaa
    12361 atcccattgt tgcaaggaat tcattcaata cccctccgtc aacattcaaa aatacataag
    12421 taatcgaaac aatgattacc caagacatga agtgagggat gtaaatgatc gtttgaatcc
    12481 cgtttttcaa tcgtttgttc gttacttcat ttaatagtaa agacaaaatg attggcatcg
    12541 gaaaaaacac gaagatattt aatccgaaca agatcaacgt atttcttaat aatgtaaaga
    12601 atgtcggttc tgtaaacaaa cgaatgaaat gtttgaaacc gacccaagga cttcccatta
    12661 ttcctaaaaa tggttgataa tcttgaaaag caataacgag tccccccata ggaagatacc
    12721 taaaaatcaa gaaataaagg actcccggca gaatcatcac atataaaaat ttattcgttt
    12781 tgattcctgc aattattttt tttcgtcttc tgagcttttc ttcttttttc gatagcgtca
    12841 gttgaaatgg ttcttgtttc tttacacttt ccataagccc ctccttagtt ttgtgaatgt
    12901 ttgctgctta tgacttcatg atagataact atctgaatta cgtatataat catttttacc
    12961 gtaagtaaaa acgcttacat agcaatgatt tttgtgctat acaaaacgat aaagtgtatt
    13021 ttttcacaaa taaactacgc atagcaaacc ttctattttt ttctatctga cacttagcat
    13081 aggaaatgat tatatacgta atctttcacc gatgataaat tgaacatata gaaacagaaa
    13141 catttaattt attttgagga ggagcctatc tatatgaaaa agaaagtctc tataggagaa
    13201 agaagtttta cacttttcaa caatacgttt ctaattttgc tagctttgat ctgtatcgtt
    13261 ccttttttaa atatcatcgc tacatctttt gcttctacac aagaagtcgt cgcgaaaaag
    13321 tttatccttt ttcctactac cttttcttta gacgcgtatc gctacattct ttctacgccg
    13381 accattttta gagcacttgc tgtttcgatt ggtgttacag gtgtcggaac gatcgtcagt
    13441 atgtgtgcaa cttcactgat ggcctacggt ctttccagaa agtatttgtt tggtcgaggt
    13501 ttcgtcaact ttcttgttgt attttctatg ttgttcagcg gggggatgat tccaacgttc
    13561 ttagttgttc gttctctagg gctggtcaat tcttactggg ccatgatcct gcctgtggct
    13621 gttaatgcaa tgaatatgat cattatgaga aactttttcc aagccttgcc ggatagtttg
    13681 gaagaatcag caaaaatgga tggttgcaca gattttggtg tatttttcaa aattatgctg
    13741 ccattagcgt taccgtctat tgctactatc tcgctttttt atgctgttac ttactggaac
    13801 acttatatga ctgctatttt gtatatcaac gattcatcta aatggccgat acagattctt
    13861 ttacgccaaa tcgtcattgt atcaagtggg atgcaagcag aaagtagtgc cgttgatgtg
    13921 attccaccag cacaaacagt taaaatggct gttatcgtta ttgcaacagt gcctatgctg
    13981 attgtttatc cttttgttca gaaatatttt gtcaaaggag cactcgtagg ttctgtcaaa
    14041 gggtgattat gtactgaacg caaaatggta gttgtgtcag aagtggtcag cttcaagaaa
    14101 taagaaggca tttacgaaaa ttgcttctta aatttttgtg aaatttcggc ttatttttcg
    14161 aagaatctac tcctggaaca ccgtgtatca gaggttgtga aagagacgtt cagccttgag
    14221 cgatgataaa aactctcaca aacattgcga cgagtaaccc acaggagcaa taagaagcga
    14281 ttttgaaaaa tagcttccca tatttcacaa aattatgcct tattgtcgat agcctgtctc
    14341 ttgaacgcca tttattcgta aaaaagaact gtgacaagac ttttgtcaca gttctttttg
    14401 cgtgcttagc cttgaaattt aactatccat aaatacaaat actagggtta ttctaacttc
    14461 ttttattgct tgaatcagtc cacaagaaaa acagcctctt gattcacaaa tatttttttc
    14521 gatattctcc cggcgtaatc gattccttct ttttaaagaa acgaataaaa ttttgcggat
    14581 ttcgatattg caatctttct gcaatctctt ttacggagag gttagtctct ttcaaccatt
    14641 tttttgctac ctctaaacga tgattttgaa caaaatcacc aaatttttct cctgtttcct
    14701 ttttaaatac attacttaaa tagttagggt tataatgcaa cctatcagcg atcacatcta
    14761 aagacagatc acgatcatat tctgtgtaga cgatatgcat aatattctcc gacaaatttt
    14821 taaattcatg atcagtgatt gcttgagagc attctgtgat tggcagaact aattgttcta
    14881 aaacaagttt ttctagttct ttgggatgat aattgttcag tgcttttaca taaatttgtt
    14941 tcatgttatc aaagtttttt gaatctactc ccaataactg tcctaattga acgagttcat
    15001 tgatcaagcg gaccgaaact acttcccgac tcaaaggatt tttattttgt gcaaacaatg
    15061 catcaatcaa ttcatgtact aaattcttca cttcctgatt tccagaacga atggcttcaa
    15121 acaatcgatt ttgttcttct atcggatatc taataagtgt tttttcatga gcagcaggaa
    15181 cgatttcctg ataaaaaata attgaacttg gaccagtatt tacacgataa tacagggctt
    15241 cttttgcccg atcaaccgat tgcttgcttt cattcagcgt ttcgaaccgg ttactgatgc
    15301 ctatactgat agttaaattc aagtattctt ttacacgttt ttgaatgagt cggcaatact
    15361 ccatgacttt tttgcttgct tctgcatcat ctttatccat tcgataaata gtggcttgca
    15421 tttcttcatt caaaacgatc ggcagcattc gattttcctt tggcacaatt tccgtgatca
    15481 tgttgttgat cgctaaaagt agcaaatcac gctccccacc gtgactatct tctaacagat
    15541 cgatttgaac caaagctgta taatagcagt cattttgaga actataacca aattgctgca
    15601 accgctgatc tagttctcgc ctttctactc gatttctaaa taaactaagt acaaatagcg
    15661 tttccagctg tggcttttgg gtaactaagt gtgcacttaa cgcttctttt tctcctatga
    15721 tccgactgac tgattgagcg accaaatcta gttctttccc actgaatcct tttgatttaa
    15781 gattcagacg ttcctgtatt tgagaaatcg gacgggcaaa tctgtccgaa aataagtagg
    15841 aaagaagacc aatgagtcct accagtgtta aagacactgc aactagcccg attctcagat
    15901 tgcggatcat tgcgccaatt gcactagagt caacttctaa tctgtaaatc caattattat
    15961 aatctgattt cagtactata tacgttttat ctttttctct tatcactttc agctgattgt
    16021 aatctagatc cacgtccgtt aatacagttg gttgctcttt attttttact gtctgagtag
    16081 taaaaaggtt gccaacttcg ttttcaatag aaagtatgtc ttctccactt tcaccaacaa
    16141 cttgttctat tgtatgtttc tctatcgtag caattcccaa tgcatatttt tctttttcaa
    16201 acattggcaa agaaatcacc atttcgattc ctttgttttt cttttgccaa aataaattat
    16261 ttttgttatt tatgtacttc tgttgatact tttcaatttc ctcttcggtc agttgactca
    16321 acgatccatt gattactccc catttaccag ccaaactgac taaatcataa ttattatcat
    16381 ccataacaat cgtttctata aaatttagtt ctttcctgat ttcagaataa gtggagtaat
    16441 ctgtatatgt cagcggatgc ttgaatatgt ccgagaaatt tttggtcgaa ccatacgtag
    16501 aaaacgaata ttcaatcgtt ctaattttcc attcaacgtt agttttaact tgcctgagca
    16561 aattcttttt gtctgttaaa taactcgatt cgatcgattc ataggtattc tggtaaatga
    16621 ataaactaaa tcctatgaca agtacggctc ctaataaaaa catcggtaaa aatattttat
    16681 aaaatactgt acttttcttc attttcttcc tctcctcctt ttaaaataaa aggctttcat
    16741 ttttctgtaa aattgatact catctaatta aatgagcatt ccccgctttc aagaatagca
    16801 taattaaaaa taaaaatcca agtaattttt aacgtgtgca atcttttcat atcaaagatc
    16861 tattgactta tcgtagttat cgtaatatga tgaatgcgtt aacaaaaagt gaaaaagtaa
    16921 ggaaaatgat ggaatggtaa cgatcaaaga tgtcgctaaa gcagctggcg tttctcatac
    16981 gacagtttct cgtgctttga ataacagcag tttaataaaa aatgaaacaa aacaaaaaat
    17041 acgacaacta gctaaggaaa tgaattattc gccaaactat agtgcaaaag gtttagtgaa
    17101 tcaaaaaaaa tatctaatcg gactattttt ctcaagtttg cataaaggaa cttcatcaaa
    17161 tttcctagca gattccattg caggcatcca ttcagtatta gacacaaatt acagtttatc
    17221 tgttgaaagt atcgatgttg ttgatttaac agaaatcaac ctgcaacgct acgatggact
    17281 gatcgttatg agtcaaagtg atgatgatca gcctttcatc gactatctca aagaaaaaga
    17341 atttcctttc gttgttgtca atcgtcacat caatgatcca gcggttatca acgtcactgc
    17401 cgatgatgcg gccggtgtta tgcaggcagt agattacggt attggatgcg gacatacgaa
    17461 gatcgcttat attggcggaa agaaaaattt tcgttcgaca aaagaacggg aaaaaggggt
    17521 attgaaaagt ctaaaaaaag cgagcatccc tgtcaatcca gcctattttt taacaggaga
    17581 ttacagctta gaaagcggcc tccaaaacat ggaataccta ttatcacttt ctgacctgcc
    17641 tactctggtt ttttgcggca acgacgacat agcgattggt gcattgagag ctgtacattt
    17701 agctggcctc cgtgttcccc agaacatttc tctgatcggg ttcgatgatt ctccagtcgt
    17761 ctcctatctc aatccgccgc ttaccaccgt acgtaagcct ttgaaagaaa tgtgtcaaga
    17821 aggaacaaag cttttactag atttgatcga aggcaggacg atcgaacaat ctaaaattga
    17881 gctctccacc ttgttgatcc ttcgtgagtc gatcaattac ttgtaaacta caagtaattt
    17941 tatataaaaa tgttaacgtg tgcataacac agaaaggaag tttatatgaa aaaactgaca
    18001 aaagaattag tgaaaaaaaa cgaagcacct gtaaaagttc ttcagtttgg tgaaggcaat
    18061 tttatgcgtg gatttattga ttggcagatt cagcagctga ataaccaaca attgtttaaa
    18121 ggtaatgttg caatcattca acctttagaa caaggtcttg gaaatatgat gaaccagcaa
    18181 gataatttat atacggtcat tttacaagga ctcagcaatg gcgaaatcgt tgatacttcc
    18241 gagattatca ccgtagtaga acaaatgatc aatccttatg atgaatggga tgcttatcta
    18301 tctctagcag aaaatgacga cttggcctat atcgtctcca atacaacaga ggcaggaatc
    18361 caattcgtgg agactgataa tttaacagat actcccccac agagcctccc gggcaaactg
    18421 acagcctttt tataccgacg tttcaaatta aacaaagctg gctttaccat cattccttgc
    18481 gaactgattg acagaaacgg cgaacgtcta aaagaaatca ttttacgcta cgcagaaaaa
    18541 tgggatttag aacctgcttt tgttgagtgg ttagaaaaag aaaatgtttt ctgttgtagt
    18601 ttagttgatc gcatcgtccc aggttatcct cgcgaagatg caggtgtttt caatcaacgg
    18661 cataactatg aagatcaatt gatggtcaaa gcagaaccat tcatgctttg ggtgatcgaa
    18721 gggcctaaag aattggagaa tcaactacca ttcaaacagg ctggcttgaa tgtcatcatc
    18781 acagatgata tgactcctta tcgtgaacgt aaggtgcatt tgcttaatgg accgcataca
    18841 gcgatggtcc ctcttgcttt gttggcggaa ttggaaactg tagaagaagt aatgaaagat
    18901 cctttattct ccgcatatgt tgatcagtta ttcaatctag aattgattcc tatgctttct
    18961 ttacctaaag atgaattagc catttatgct gaccaaatca aagaacgttt cttgaatcct
    19021 tttgcccatc acaaattaga agcgatttca ttaaatagtg tttcaaagtt cagcacccgt
    19081 ctgcttccag tgttcaagaa gtatatcgaa gaacaaaatc aggtaccacc gttaatcact
    19141 gtttcactag ctgcgctact tcttatgtat cgaggcgatc aagtaaagcc acatgatgat
    19201 gaaaagacga taagcgaatt tactgatgct tggtctgata atggaacagc tattcctcga
    19261 ttattgcaaa acgctgcgct ttggggagaa gatttgtctc aaataccgaa tgtgacagat
    19321 acagttcaag aaatagctgc aaagatcgat caaaaaggtg tccggtcagt attacaagaa
    19381 atgaaaggaa cgatggtcca tgcttgaaac cctgcaacca acaatgaaat taaatcgacg
    19441 agacagtgtg gtcgtcgcat taacccctat tccaaaacaa acacaactga cgattgatca
    19501 gcaaacgatc accactcttg aagatatccc gcaaggtcat aagattgcat tgggtgattt
    19561 gaaagctgga gacaacgtga tcaaatatgg ctatccaatc ggtcatgtga cgacagacgt
    19621 aactgccggt caatggctgc acactcataa tgtaaaaacc aatctttctg gtgaattgga
    19681 ttatcgatat gaaaaagatg tccatccaag tcattacctt tttgagaacc gaacatttca
    19741 aggttacttg cgaaaaaatg gaaaagtagg gattcgtaat gatttgtttt tagtacctac
    19801 cgttgggtgt gtgaatggca ttgctgaact gatcgtcaaa cagttcaagg aaaaacatcc
    19861 agatctggga cagtttgacc atattacgat tttaaagcat ccttatggct gttcgcagct
    19921 tggaaaagat catcaaaata ctcgagaaat tttagcggac gcagtaaatc atcccaatgc
    19981 cggaggagtt ttagtatttg gattaggttg tgagaacaat acagttcctg aattcaaaaa
    20041 aattttaggt gaatatgatg aagaacgagt gaaatttcta gtggctcaag atgtttacga
    20101 tgagatcgaa caaggtgtgg ctctattaga agagctttta acagcggcgg aaaatgacca
    20161 gcgcatatca gtcccgctct ctaagttgaa tgtcggtttg aaatgcggcg gttctgatgg
    20221 tctatcggga ataactgcta atcctttact tggtgcattt tctgactact tgattgctca
    20281 aggaggcagc acgatcttaa cagaagtgcc agaaatgttt ggcgcagaac aagtattgat
    20341 ggcacgagcg gaaaatgaag aagtttttga ctcaatcgtt gacttgatca atgacttcaa
    20401 acagtatttc ttgtcttacg gggaaccagt ttacgaaaac ccatctcctg gtaataaagc
    20461 aggtgggatc actacattag aagataagtc tttaggctgc acgcaaaaat caggaagctc
    20521 tcctgtcgtt gatgtgctac aatatggcga aaaaatcaga aaaccagggc ttagtttatt
    20581 gcaagctccc gggaatgatc ttgtagctgc ctctgctctt gcttcatccg attgccagtt
    20641 ggtcttgttt accacaggaa gagggactcc gtttggctca tatgtcccaa cggtcaaggt
    20701 atctacgaat acaactcttt ttgaacgcaa aggtcattgg atggatttta atgcaggcgt
    20761 cttattagaa caaccaatgg aagtaatctt agaatcgttt gttcaaaaaa tcatcgctgt
    20821 agctagtgga gaagaaacga aaaatgaaca aaatgacgtt cgagaaattg ccatttttaa
    20881 aaacggagta acactttgat tttcataaaa cagtataaaa agaaagaagg aagatttatg
    20941 tttttatctg atgatttttt attaaaagac gattgggcga aaaagcttta ccattcctac
    21001 gcaaaaaaca tgcccattat tgattatcac tgtcacttag atccaaaaga aatttacgaa
    21061 aacaacaatt tcagcaatct gacagaagct tggttaggag gcgatcatta caaatggcgc
    21121 ttgatgcgag cttgcggcgt gcctgaagaa aaaatcacag gaaatgcttc tgattttgaa
    21181 aaatttttag cttggtgtca aaccgtacca aaaattatcg gaaatccgct ttacagttgg
    21241 tcacatcttg aattgaagcg tttcttcggt attgacttgt tgataaatga agaaaatgca
    21301 gagaaaattt ggacacaagc aaatgaaatt ttggcagctc ctgattttcg ccgtcgggaa
    21361 atcgcaaaaa aatcgaatgt agaagtgatt tgtacaacag atgatcccgc agacgacttg
    21421 cactatcatc agttgcttgc tcatgaagaa ccagatttga aggttctacc ttcattccgt
    21481 ccagataaag cactcaatat tgaaaaagaa ggatttaatg catgggtcac actactggaa
    21541 gaagcagctg accaaacgat caccacctat caagaactga tagaagtctt agggcagcgg
    21601 atagaatact tccatcaaca tggatgtcgt gtttccgacc acgctttaga catcttacgc
    21661 tataaagaag cggatgaaac agtattagaa gagatttttc aaaaagcacg agctaacaaa
    21721 ctattatctt cagatgaaat cgatgcttat cgtacagaaa cactgataca tttgacccac
    21781 ttctatcatt ctcataattg gacgatgcag ctgcacatcc atgcttatcg taactgtaat
    21841 acacaaatgt tggaaaaatt agggcccgat accggctatg atggaatgaa tgatctttct
    21901 ttgactattc ctctgcaaaa attattgaac cgtgcagaag aaacggatca gttgccaaag
    21961 acgatccttt attcattgaa tccgaatgac tatcctgcga ttttagcttt gatgggctgt
    22021 ttccaaaaag aacagaatgg aaaactgcag ttaggttctg gatggtggta caacgatact
    22081 cgagctggta tgcgcgatca attgacacaa tttgctgatg gtagtgcttt ggggaatttt
    22141 gtcggcatgc tgacagattc aagaagtttc ctgtcctaca ctagacatga atatttccgt
    22201 cgtgttcttt gtgaattttt aggcgaaatg gtcatgcgag gagaagcacc tgaagatgaa
    22261 caacttttag gaagtctagt tcaagcgatt agttatacaa atgctaaaaa ttactttggc
    22321 ttttttgcct aattgattaa tagtaacagt aacgaatcaa aaacaggata gtgaaataac
    22381 ggaatccgtt tatccacgtt ttagagaaga agacggacca aatttgctcc gtcttcttct
    22441 cttgctgttc tgcttcattg cctataaacc tttatgaaag aagagataac atgcctacta
    22501 tccatattgc cggtgattct actgcggcag aaaaagatga aaacaagcgt cccgagacag
    22561 gttggggaga aaaaatctct gcttattttt cacccgagat ccagatcaat aaccaagcaa
    22621 agaatggacg cagcaccaaa tcatttatcc aggaaggaag gttagcccgt ctagcttcac
    22681 agtttcagcc gaatgatttc ttatttgtac aatttggaca taacgaccag aaaatccaag
    22741 aagaaagagg tacgcttccc ttcggtagct atttaaaaaa tctgcagata ttttttgaat
    22801 gcgcaaaaaa agcgaacgtc caaatggtct tactgacatc tgtgacgcga cgagattact
    22861 tagaaaacgg aacattgaat ccagatatac ttggagacta tccaaaagcg atgcgtgcat
    22921 ttgctgagaa acaccatatt cctcttttag atgtgttctc aagatcacaa gaattgttcc
    22981 agaccttctc aaaagaagag acaaaaaaat tctacctgca tcttatacct gatacttgta
    23041 aaaattaccc agaaggacta aaagacaata cccactttag tccagaaggc gctgataaag
    23101 ttgcccgaat aattgttgaa ttgataaaag aatcccgtct gcctcttgct aattatttac
    23161 aaaaaggagt ttgagatgtt tccattaaat ttaggcatcc gtgcccacga tttagatgtt
    23221 cgaaatcgtg aagaaatcgt tcaaaaagta tcacagcttc acttgtccca tatccaattt
    23281 gcaccacaaa aagcatttcc tgaacaactt aaattaactg acatgacact tgggagtgct
    23341 gcctattttg gtgaatactt ccaaaaaaac aatatcgaac tttccatttt aggatgctat
    23401 atcaacctat ccagcaaaaa tcaagaagtt cgtgcacaag cattggcaac tttcaaacag
    23461 caaattgctc tgtgctctgc ctatcaagcc aagatgattg ctacggaaac cggtagtgtc
    23521 tctgtcggtt acacaaaaga aaattttact gaagaagctt atcagatcgc cagaaattct
    23581 atcattgaat tagtcgctca tgcagaaaat tttggcgtaa ctgttgctgt tgaagcaggg
    23641 atcaatcatc caatctataa ctatcagtta gctaaacgtt taatcgatga agtagcttca
    23701 ccaaatttaa aaatcatttt agattgtgcg aatttgatgc ataaagaaaa tcatgctgat
    23761 caggaaaaag tgatccgagg tgccttggac aatttacatg gttatattac agcgcttcat
    23821 ctcaaagact atatcatgga aaatggaaag atccgcatgg tacctgttgg caagggctgt
    23881 ttagatttcc gcccggtact gcattatatc aaatatgagc gtcctctaat gtacgccact
    23941 cttgaagcta ctcctgagat ttatgttcct gaagcaatag aacacttgca gtttatttac
    24001 caagattgtt aaggagaaga ttatggagga acgaatacag aaaagttatc aaaaatatca
    24061 tgcaaatgct tttcagacat tgctgcatct ttatcaggga aattattggc gttttgccat
    24121 gtcaggactc ttttttatta tcaaacatct tccatcttgg ttaatgccga tcgctattgc
    24181 caatgtaatc aatgcagctt catcgaaaga ttcttctcag ttgcaggcca tttatttcaa
    24241 cgcttttttg atggcttgtc tgattggtca aaatatattg acgaattatt ttcatgtaaa
    24301 ataccatagc acttcgatcc gtcaagtaga agctggacta agagcgaccc ttatcaagaa
    24361 aatccaagaa ctatctattc cttatcaaaa agaattgcaa tctggacgaa tccagtcaaa
    24421 gatcatccgt gatgtagaag ctatccaaac gttgtcctct caagtatttg tcagcggatt
    24481 aaatatcgct gtcaatttat tcgtagcttt aggtatcacg ctttataaaa gtcctgttgt
    24541 tttcatgttt ttcttattga ctgttcctct cgccgcattc gttactctct ttttccgtaa
    24601 aaggatcaga cagtccaact cagacttcag gcaagaaatg gaagagactt ctgcaaaagt
    24661 gatcgaagtg atcgaattag caccgattgc tcgagctcat gggttagaaa aacacgaaac
    24721 aactcgctta aataagcatt ttactcaaat ctatgaaaaa ggattccact tagatatcct
    24781 gcaatctgtt ttcggatcag tcagctgggc tagttttcag atatttcagc tgatttgttt
    24841 gattttcact gggatattag ctttacaagg gcgcatccaa cccggcgatg tcgtgatgta
    24901 tcagacgtat ttcacgacga tcgtcaattc cgtttctgga atgatcacgc tgattcctac
    24961 gatttcaaaa ggcatggaat ctatcacttc tattggcgaa ctgttgattg ctggcgatgt
    25021 agaaacttat cacggtaaga aaaaaatcca acatttggat ggaaattttc gttttgagga
    25081 tgtttctttt ctttatccgg actcactcaa accgattatc gatcattttt ctctagaggt
    25141 gaaagctgga gaaacaattg cttttgttgg gccatctggc tctggaaaat ctacactcct
    25201 taacttattg attggattta tccagccgac ttcaggaaaa atttttctag atgatcagcc
    25261 tttggatgaa ctggatatgc gaagtgtgcg aaattattta gccgttgttc ctcaaaccac
    25321 tttgttgttc tccgcttcga tcaaagagaa catcacttat ggcttgaaaa acgtatcaaa
    25381 agaacgttta gatgaagtca tcgaagctgc gcaactttct tcactgattg accagcttcc
    25441 tgatggtctg gataccttag taggcgaaca tggcaacaag ctgtctggtg gccaaaagca
    25501 acgtatctcc attgcacgag cgttgatacg tcagccaaaa atcattttgc tagatgaagc
    25561 aacctcagct ttagataacc agtcagagaa aaaaatccag caagccctga attacctgac
    25621 agaaacaccc actactttta ttgtggctca tcggctttca acgatcaaag aggcagataa
    25681 aatcgttgtg atcgatgaag gaaaaatcgt tgaaataggt acttacgaaa aactgttagc
    25741 tcaaaaaggc tatttctacc gcttgaaaaa tgaatgacaa aaaataggag ctatgacaag
    25801 acttttgtcg tagctcctat ttctgaataa acggtgttct cctgccaact cctcggtcac
    25861 aagtcacaat agtcatcaaa catgagaagc tgttttttga aattgttcct tgtaactcag
    25921 agttaaacgg taggctcacg acctcttggt aaatggtgtt caagagacag cctatcggca
    25981 ataagaagca attttgtcat cgctcaaggc cgaacgtctc tttcacaccc tctgttgttt
    26041 cataaaatag ttttattcgc tgtaaaggtc gcgaactggt gtcatgatga tacggttcaa
    26101 gtcattgatg attgtactga agccttgctc tttttgcatc aagtcattga ttacttcttc
    26161 tgattggatt ttcacagcca tttcttgtgc tttcattgca tcttcgtcgc tgaactcttg
    26221 tccactcatt tgtttttctt gtaattcgat ttgcatcgct tggaagtctt tgaacagttt
    26281 gtgtgcttct tcgtttgctt gtactttctc gtacgcttct ttcaacgctt tgaattctgg
    26341 taattcacgg atctcacgtt cgatttgatt cgcgctatcg tagatgtttg acatgttatg
    26401 ccctcttttc ttttagtagt tactctctat tgtaacatgg ggttattcgt tttcaaaggg
    26461 gctactctcc ttgatatttc cgccagaggt ctttagccgc ttcaccaatt ccctgaacgc
    26521 cttctttcac catatcgccg aagtttttca gcccttcttt tgcttgttca ccatattgat
    26581 tcaagttatc ttgccaattt ccagactctc cattagaatt tcctgtgttt ccaacttgat
    26641 ctgcagctac cacttgtcct cctgtggcat aggcatctgc tacactaaat cctgtttttg
    26701 aagtatacgg aaggatgcct tctgccgctg atttgaagac tttcccgaca acatttccac
    26761 ttgtcccttc caaatagtgc agcttgctgg attcttcgta acccatccat gtcgaaatca
    26821 ctacgtctgg cgtgtaaccg atcatccatt ggtcatttgc ttttgtggca tcgaaattag
    26881 tttctgtggt tcctgttttc cctgctatcg tataacctgc aggattcgca gcagccgctg
    26941 ttccatttga aaatgtacca agaagcatgc tggtcatttc atcggctgtt tcctttgata
    27001 tgacctgttt tggttttttg tttgtgttat cgacgatcac cgctccagtc gaatcaacga
    27061 ttttcgtgat aagatgcggc gtatacatct gaccatcatt ggcaaatgca ctgtaagcac
    27121 ccgccatgat caatggagat actccttttt ccagtccacc aagggctaag ccataatact
    27181 tatcagattt tgctaaaggc aggccgaatt cttctgcttt atcatatcct ttttgtaaac
    27241 cgatctcatg caaaagccat acagtaggca aattcaaact ttgtgcaaca gcttgataca
    27301 tcggtacttc tccttggtat gtcccgtcaa aattatgcgc atcgtaataa ctttgcggtt
    27361 cgtctttcaa gatactggaa ggcttgtatc cagcttccag tgctggtgta tatacgctta
    27421 atggtttgat cgttgatcct ggtgaacgac gcatctgtgt agcaaagctg aatcctctaa
    27481 agacatgatc tcctcttcgt cctactagtg cttgtacacc acctgtattc ggatctaaag
    27541 ctactgaagc agattggacc atggcaccat ctgaagcatt tgctgggaat aatgcactgt
    27601 tttgataagt agcttctaat tgcttttgat aatcctgatc taaagctgta tagattttat
    27661 agcctttatt catgacatct tcttcatcaa gaccatactc gttaactgct tcatcgatca
    27721 ctgcatcaaa ataataagga taacgataac cagaatctga attatcgtat gtgtcattaa
    27781 gatacgcgct gatatctgtc tggctttctg cttgttcttg ttcttttgtg atttttccgt
    27841 tttcttccat tacacttagt actgtgtttt tccgatcatt cgcatttttt gggtgatcga
    27901 tcggattata aataccagga cctttcagca ttcctgccaa agtagcagcc tcagacagcg
    27961 taacattcgt tgcatctact ccaaaatact ttctggaagc gtcttggaca ccccataccc
    28021 cgttgccaaa ataggcattg ttaagataca tggtcaagat ttcttctttg ctgtacttct
    28081 tttcgatctc gattgccaaa aataattcct tcgcttttcg atcaaacgtt tggtctaatg
    28141 tcagatacgc atttttggca agctgctgag tgatcgtact tcctccgccc cctgatgttc
    28201 cgccagacaa gaccattcgg actgctgcac gggcaatccc tttgatatca aacccgtgat
    28261 gctcgtaaaa attcctatct tctgtcgaga ttactgcatc ttggatatag ggagaaatcg
    28321 cgtttaattc tacatatgtt cctttttggg cgtacagtgt gccagcttct tcgtttttct
    28381 tatcataaat gactgtcgat tggcttaatc ctgattttaa cgtttcgaca tttgcttgtt
    28441 ttgctaaaat aaagaggtag atacttgtca ctaagacaca gatcaaacca atcagcaaaa
    28501 tcaatttgtt cacatgatat tttttccaga tgcgctttcg ccatcgatgg aattgtccga
    28561 gatatggtct gatccaacgc caaaaactga tcaaagcagc ttttatcttt tctaaaatgc
    28621 tttgaaaatc catttgcttc ttctcctgtc tatttgattc aatcgtctta ttttaccata
    28681 gtgaaagagt gttttcttcc tgcttaagtt gtagttcaat atgttttttt acgttagtgc
    28741 aagtagagta acataagaat gaacagaaaa atgtaagttt tttcttaaat atgttttaaa
    28801 aatggtacaa ttagtctgcg attgcactga aaggagtaca cttgtgaaaa tcacgatcac
    28861 tttacctatg aaccatcctg aaacaacaat tcgcgacttg cttgaaaagg aatggttagt
    28921 tcctagaaag gttcgacact ttttgcgtat acgtaaaaac gtttggatca atcaacaacc
    28981 tgctttgttc catcatgaag taaagggcaa tgaccagatc acattgttat tcgaagaaac
    29041 agattataat tatcaagaag ttcaattagg agatgcgaag cacatccgtg ttttatatga
    29101 agatgagcat ttgattatag tggataagcc tgcaggaatg aagactcatc caaatgaacc
    29161 gacagaaaac agtaccttac tcaatcattt agctgcttat ctcgacacta aacagcaacg
    29221 accttacgtt gtccaccgct tggacaaaga aacaagcggt gccgttttat ttgcaaaaaa
    29281 tccatttgtc ttgccgatac ttggaagaat gttggaacaa aaaatgatct atcggagata
    29341 tcaagccatc gtatggggag aaattgccaa agatatgacc atcaccaata aaattggacg
    29401 agatcgccat gatcggagaa aaagggtcgt agatgataaa aatggtcaga gcgccttgac
    29461 acatgtcact gtcaacaaag tactttctga acaaacacaa gtctattgtg ttttggaaac
    29521 cggacgtaca caccagatca gagttcattt agctcataag ggacatccga tcgttggaga
    29581 ccctctctac caaaatagaa cagctgaacg actgatgctc catgcattag aactgcacat
    29641 gatccatcca tttactcaag aaaaaatagt cggtaaagct ttacctggat tatgggaata
    29701 gaaataaaaa agaacagagt cttatcagca gataatgata agactctgtt ctttttgtgt
    29761 aatttgtctg cttacttttg atgttcgtgt tctgctaaca gcaaactacc gataatccca
    29821 ctttcattcg gcagtcccca acgaacgata tattcactta cttgaggtgt ttccatataa
    29881 ccacccatca attcaacaaa ttgctgacgg attttttgaa ggagatgatc ctgattcatt
    29941 accccaccgc ctaaaataat cttttcaggt gctaacgtca acgtatagtt gatcagtgct
    30001 tgagcaatat aataagcctg aatagcccaa acaggatgat cttgcggcag atcttgccct
    30061 ttgatccctg tgcgtgcctc aatagacggt cctgctgcta atccttctaa acaatcttta
    30121 tgataaggac aagtaccttc ataatggtca tctggatggc gtttcaccca aatatgtccc
    30181 atttcaggat gtgcgatccc tgaaaaaatt tcttcattga tcacgacacc tgcaccgatt
    30241 cctgttccca cggtaaggta aatacaacta ttttttcctt gtgctgctcc ttgcttcaat
    30301 tccccatatg cagcagcatt gacatccgtt gtccaagcag caggaatatt gtagcgttcc
    30361 ttgattgtgc caagaaaatc gaattgtgcc cacccttttt tgggagttgc caaaacgtat
    30421 ccgtaattat cttttgtttt gtcgatacca atcgggccga atgagccaat cccgattccc
    30481 ttcaattcat aacgatcaaa aaattcaaat acctgatcca atgtttcttc tggtgttgtg
    30541 gtagggatac ttaatttttc taaaatttct ccaccatctg aaaccgcaca cacaaatttt
    30601 gttccgcctg cttctattcc gccatacatt cgttttcctc ctcgaatccg attgtccgaa
    30661 tctcataagg ttggattatt gggacaaccg cttgcttcgt tggttcttca agcagattca
    30721 atatgacagt ttttccattg tctttagtta tttccaattt ttctaaatga ctagacatat
    30781 tgaaacctct tactactact ttatcactaa acttgctgcg tttcaaagct gtaattgcaa
    30841 acgtttcact ttttatcgtt aaatattgtt gttttgaaat caatgttcct tcatgatgtt
    30901 tgatttgttg agtggaaaaa ggaatctgtg ctgcgtatgc atgcaaataa gtagagaatt
    30961 tttcttctgg tccatgtagt tcaatgctgt aattgaaccg atgctcacct agacactgtg
    31021 cttctggtgt tggaaaatat ccccaatcgc ctagttctcc cacactgcga agtagcgtca
    31081 ctgcgatttg tccgtcttct gttacttcat attcattcaa accaaagttt ccgactgtta
    31141 caccgtactc ttcatcatga atattgacaa atgcttgctg atgttgcgga ttcgtggggt
    31201 tttcccaact tttagacaca tggtttgggc gcttcaccac ttcaaaaata ctatctgctt
    31261 cgtgatgttc cacatgtaac tttgtaggaa acaagacacg taagcgatga tctttcatct
    31321 gattgtcgag agtcgtttca aagtcgattt ttttactatc ttttctgatt gtcatgattg
    31381 tttttatttg aaggattcgt ttttctttgg atcgttctgc ttttcgataa cgaaattcca
    31441 caaccatctg ctgttctttt tctaaacgct cgtctgcaga aacagggatt tccatttcct
    31501 gtagaatact tatttttgct atttccggtg tatctactaa tacttttact tcagagtttt
    31561 ctttgttact ggataggatt ggctgatcac agaaaggttg tttaaagata tactcatttc
    31621 ctatatcgcc gatatcttca aaaatatgca gattattcaa ctttcgtttg tttttgcgat
    31681 cttccattgt aatggtacca tttttttcaa tcgtcaaatg tagagggccg ttttcgatga
    31741 ttcgtccact ctgatgaatc attgtttcct tttcttctgc tttcgcttcc ccttctacaa
    31801 gcgcgaatgt ttcccaagaa aatgctggca tgttttctaa tggtaaagtc actttgatca
    31861 ttcttgccat atatggcaca cggaaacggt ctttcggcaa atcataacca aattggacag
    31921 tttcttcaga taaaatagct ggtatagtgg ccccactttt tgtttctaca tgatacttac
    31981 gtttaggcaa attttctaac tcttgatata gttgttcagg tattccttca gcgaatcttt
    32041 ttctttctaa ttcgatggtt atttctgctt caccagtttt atccattcct gcagtattta
    32101 caatgacaaa tggaaagctg tcttttggga atccggtcgt atcgattgct gcggtcagct
    32161 gttctaagga atcttgtgca agatactttc caacttcatc tgctttttca aaacgaggta
    32221 tcatttcccg atggacagaa tcgactgaac aaccgcaaat actgtcgtga ggatgatttt
    32281 gcattaatgt cttccaagca taatctaatt gatcatgggg atagtttcca ctaacttcat
    32341 aagccatcgt cgcaagtggt tctgtaatat tttctagctg tcgctggacc ttggtattcc
    32401 attgttttaa gtaaacccga gcagatgctg tattggctaa agtataccag ccatccgttt
    32461 cttgacttgt caattctcct tctactgagc ctaagtcttc tggcacatct ttttgaactg
    32521 cttccagata gtcagtaaaa ttagaatgaa taaactcgta atctggaaac agttcatttg
    32581 cgagatggat tgcttttgat atatcttttt gtaccggttg atgatcaaca ccattcatca
    32641 tcaataagtg gttcgtagag gcatattgtt ctgcatccgc taatttttgc ttccaaaagg
    32701 caagagctgc ttctttttct actggaatct cattcccgtt gctataccaa ttggcaaata
    32761 gcagaccaaa gattgctgtt tgatcaggtc ctttccacca catctctgag tattgggaag
    32821 aatagttttc tgcttccaaa acttgattat caaagccaat tggttttaca ccacggccaa
    32881 acgctgctgc tgaaatacca gcttgtttca ttaattgagg cgtctgtccc atatttccaa
    32941 atgtatcggg aaaatagcct aacatgacag gggttcccca tttacggctt tcttccatgc
    33001 caatcagcat atttctcacg ttcgattccg agctgataag aaaatcatct tgcaagatat
    33061 aaaatggtcc aattctcaat tttccttcat tgattgcttg ttggattgcc tgtctttttt
    33121 ctggccttac ttgaagatag tcatctaaaa taatcgtttg cccatccaaa tgaaaactgt
    33181 tgaaggacgg atcaacttca aatagctcta gtagatcgtc tatcaattca atcagtcgca
    33241 tgtgatgctg ttcgtaagcc atgtaccatt cacgatccca gtggctatga gaaatgatat
    33301 atactttctt tttcatttac gatacctcct acttttctac tctaatatca aagtaatcca
    33361 tgactaattc gcaaaacatc atatttgccc aagaaaacca ttctctcgta taattttcag
    33421 gattgttcac atcgaatcct tcgtgcataa ggtgtgttcc tgcgtcagtt gctacaagta
    33481 aattcaatat ccgctctttt tcagatttgt ctgacgttgt cattccttcc atagctaatg
    33541 caatcggcca aacgtatttt tctggcgtat gggaggatcc aattcctttt gcgtactttc
    33601 cttcatagaa atatggattt tctttactca acaatgttct tcttgtttgc agataatctt
    33661 cctcttgttc agaacaatat cccaagtaag gtgcggcgat cagattgggc acattactgt
    33721 catccatgac tgtggcgttt cccattccat ctacttcata tgcataaatc gtttgccctt
    33781 tttgattaac cgttcgtccg tgattctgaa tcccctcttg gatctctttc ttcaatttct
    33841 gtgtttgctg tacaatttct ttatcatcga gtatcgtttg aaaaatttct tccacataac
    33901 ctaacacgac caccgcaaac atattggatg gtaccagata tccataacgg caagtatcat
    33961 cgctaggacg gaaaccagac catgtcattc ctgtaaaagc tgtttttgca cctcgcccgt
    34021 cattgatcag cgtatcttct tttcttgtcg tgtctcgtac aaatgtataa ggagagtgtt
    34081 catgatcttg ctctgttttg aacacgtcca agattttttt gataccttca ataaaagatt
    34141 gattgaattg atcagttttt cctgtatttt tgtaaagaag ataggccaac tgtattgggt
    34201 agcataaaga atcaatttca tattttcttt cccagatcca atcgttcatt tttgtatgat
    34261 ctgtttggtg gccagcaccg ttagcttctt cgttgaaggc attcgcatat ggatcgatat
    34321 tgatataaaa aaattgcttt ttgactaacc cgctgatcat gtcagctaat tcctcatctt
    34381 cttttgcaat cactaaataa ggacgaactt gtgcagtaga gtctcttaac cacatcgctg
    34441 gaatgtctcc cgtcaataaa aaggtggttc cgtcattttg ctttttgact gttgtcaaca
    34501 gagtattggc aaatgctgct gtaaaattct ttgcccagtc cgcatggata tccccacatt
    34561 tttgtgtgat atcttccata aatttctgca ccgattttgg tatatcttta taagccacta
    34621 ataaaacctt ctttctattt gatatatctt taaagattat actttataca gccaattatg
    34681 tctacgcttt caaaaaatat ctttttattt actttttcat ccattatggt attatttgaa
    34741 tatgatatat cattaagagg tgtttatatg aatcaaccat tgtaccagac aatatttaat
    34801 gatttgcaaa cggctatttt aactggtgaa ttacctgtag acagccaact accaactgaa
    34861 aaagaacttt cacgtaccta taaagtaagc agaatcactt ccaaacgtgc attgactgaa
    34921 ttagagcaat taggacttat ttatcgcgtt cgcgggaaag gcagtttcgt taaatccgct
    34981 tctccggaac agattcttgc ttctcctaca aaaacacgac ggattctgtt tcttcttcca
    35041 tatgtcgctg atttgtctgt tggtgatttt agcaagggat tgaaccctgt gatgcaagat
    35101 aaacagattg atgtcatgat gacgacgctt gactttctac aaaataaaac agcaaaagag
    35161 ctaatcaatg aatttgacgg attgatttat tatgctcttg atacagaaca acatcttgac
    35221 ttactttttg agctttcatt gaaagaattc cctgtcgtca tattagataa aaaaatctat
    35281 gagttacctt ttcctaccgt tctttccgat aatttccaag gcggtgcgct tgctgcctct
    35341 tatttgatcg aacagggaca ttcaaaaatc gcttatttgt ttggtacgca gactcatcca
    35401 caatccgttc gacagcgtta ccttggttac cttgaagcat tggacaaagc tggtttgact
    35461 ttccacactt cactggatga caaaagcgcg acattagatg aattgctttc ttatatcact
    35521 aagtatgaag taactgcttt tgtttgtgaa aacgatgttg tcgctatcca gaccatgaat
    35581 ctcttgagac agcatggtta tcatatccct gaagattttt caattatcgg atttgatgat
    35641 atccaagcag cagctcttgt tgacccgcca ctgacaacca tcgcacaaga ttttgaacag
    35701 ttaggtaagc ttgcgggaga tgctttggtc acttggttag agacaaaaga tcgaccatcc
    35761 gatagtaaat ttccagtttc attcatcaaa agacaatcaa caaaggagaa ataaaatgaa
    35821 tatcggtcaa atagatacta gacatgcaac agcgaatcag ccaaatttct ctaatgggaa
    35881 ctgccagcct tatactggcg ttccttttgg gatgaattat tttgcaccgc aaactacgga
    35941 tcaaaacggc agctggtggt ttcatcctga tgaccgcgtt tttcaaggct accgtcttac
    36001 ccatcaacca agtccttgga tgggtgattt cagtcatatg ctgtttacgc cgatcaatgg
    36061 aaaactacag gagaacaccc ttttccatgc tcaaagttct taccgcccag aagaaagtat
    36121 attttgcccg actcatctgt cgatctgtca attacgttat ggcatctgtt ctacattgat
    36181 acctagcatg tatggcggaa tcttatctat tgattacagc aaaaatgaca gcggtttact
    36241 tttatccttt ccgggacgcc atcagctctt tgttatagat ccttacacag tggaaggaaa
    36301 aatcacacat tttgctggtt cagaagatcc tgatttttct ttttatttta tattgagatt
    36361 tgaatatcct ttaacaattg atgagttagc tgtttccaac aaaaatagcg actcgatccc
    36421 gttgtatttt gaacagacaa aaaaacaaac tatccgattt gggacatctt ttatcagctc
    36481 ggaacaagca gcttataacc tggaactaga acaaaaccaa agcaaagaga cttaccttgc
    36541 tcacagtcaa gaacaatggc agtcctattt tgatcgtata cagctcacac accatgatca
    36601 acaacaattg cggacgtttt atcataattt atatcgggtg tttttatttc cacaaacatt
    36661 ttatgaaatt gatcctagtg ggcaaaaaat ccactatgat acgactagtc gatctataaa
    36721 acctggtgtt ctctatacaa ataatgggtt ttgggatacg tataaaacgg tttatcctct
    36781 ttattctttg attgctgtag aaaaatacga agaaatgctg gaaggttttt tgaacagcta
    36841 tagagaaagt ggctatttgc caaaatggct gtctcctgat gaacgtggac ttatgcctgg
    36901 gacattgatc gatgcggtca ttgcagatgc tgctgtaaaa gatatccgac gagacttgat
    36961 gcctgaattt ctaacggcaa tggaaaaagg tgctacggtt caaagcaaac atccaaatta
    37021 tggacgccaa ggaacagaag attacttgac atatggctat gttcctaatc actaccacga
    37081 atcagtcaat cacacattag actatgctta tagcgatttt tgtattagcc aagttgccaa
    37141 ggtactagaa gaagaggaaa tgacgaagaa atatcagcag caatcattga actatcaaaa
    37201 tatctttgac tatgagtcag gatttatgcg ttcaaaagat aaagatggca agttcagaga
    37261 accattttca gctaatcgtt ggggacaaga ttatgcagaa ggaagtgctt ggcaaagcag
    37321 ctttgctgtt tatcacgatt tttcaggact gatcggaaaa tatggtggca gtgagagata
    37381 taaagaaaaa ctcattgagc tgtgcaatca gcccccaacg tttgacccag gaggatatgg
    37441 ttttgagatc cacgaaatga gtgagatggc cgcgatagaa tttggacaat tagctatttc
    37501 aaaccagcca agttttcact atccttactt gttcagttat ataggacaac ctgaaatggc
    37561 acagccactg cttaaacagt tgatgactca gaccttcgac gattctccaa tgggttaccc
    37621 tggagatgag gacaatggaa gtatggccgc ttggtatatc ttcaatagtc tgggatttta
    37681 tcctgtcacg cctggaaccg gtgaatatgt tatcggtatg ccattaattg acaaggctgt
    37741 tttgcttttg tcaaatggaa aggaattgac gattgaagca acgcctaatc ggccgcagca
    37801 acaatttatc cataaaatca aacggatgga caaagaatat acgaaattat attttaccca
    37861 tcaagatttg ctgaaaggcg gcacgatctc ttaccaatta gggatcatcc ctcaccctaa
    37921 gaaatatcaa gcaaaagatt tgcctttttc cttatcaaac tataattaac aagaggttgt
    37981 gaaaaagctg tcctgcatca agtaataaga acagccaagc aaaaatagat cctcatattt
    38041 ttcgtttggt tggtcttatt accgcagatg caagcttttg aacaccgttt attgagaggt
    38101 tgtgaaatca gcgttctgac ctgagtatta gagagacaaa tggcaaaata gttcctcata
    38161 ttttgccatt ttttgagcta ataccgaggg tcagctgatt gaacaccgtt tagtggagag
    38221 gtcgtgaaaa agctgtttag tttcgagtat taagaaaaat tttgtgaaaa tggctttcca
    38281 catttttgca taaatttggc ttaataccga gaaactggct tttgaactcc gtttatcgag
    38341 aggtcatgaa aaagctgcct tgcctcaagt aataagaaca gcccaaaatt agatttctag
    38401 acaatttttt ataagttatt tcattacatt ggctttttct tttatgattc tccactgttt
    38461 tctcggtact ctttagggga tctgccgacg attttcttga ataatttaga gaaatacgtg
    38521 gtgttgttgt agccaatctc acttgctatc tcattgatgt tttgattact gtgcaaaagc
    38581 agttgtttcg ctttttccat acgtaaatgg ttcaaataag ctgaaaaact ttttttcgtt
    38641 tcttttttga acagctgtcc tagatacatg acatttaaat gcaggttttc tgacacttct
    38701 ttgagtgtaa gtggttcttg ataatgctgg tgcaggatta cgattacttt ttccacattg
    38761 tcactgtact ttttctgtct ctgatgcttt ttgatgaatg acagaagtag ctgctgaagt
    38821 tcttgcaccg tttttgcctg atggattttt tcgattcctt gtaaatattc ctcatcttcc
    38881 agatcaatca attcccgttg aatctccata aacagtaaaa aactggaata tcgtatatct
    38941 tccggcatca tggctgctaa ctgaaactgt tcaaaaaaat cagtgatcat tttttgagcg
    39001 acttccaatt gtttattttg cagcacgcgt ctgaaacttg aaaaatcgat ggtttgatct
    39061 tttgtttctg cttgtactgc gtaaaaaaca tgctcgtctt tatctccata aaattgatgc
    39121 aactgtagat tgtctttcgc ttgttggaat gtttcaggga ttttgtccaa agaatctgtc
    39181 tcttccccga tactgatcag ccattcctga tcaggaaagt tttcttgaac aaaacaacag
    39241 aagccatcaa cttcatctgc ctccaacaac aacgtgatca atacacggtc tccgtaattt
    39301 cgttgatagt aaaagatttg ttgccgttct tgcaaccatc tattgataag agtatcatga
    39361 gttcttgcca gttgaatcaa tactatccta tgctgcttct cacttatttg tcctattatt
    39421 tcttcttcac ttatttcatc caattcttca ttcaaccatt gactgaataa cagttcttga
    39481 tagatttctt gttgattttt ttgttcattt tgctgatcta accgtgtttt gattttcttg
    39541 aggctttcaa ccaattcgaa cttattcacg ggtttcatca aataattcac ggcgcctaat
    39601 tgcatacctc ctttcaaata atcgaattct tggtatcctg ataaaatcat aaattcaaaa
    39661 ttatgacgtt ctttttgagc cgcttcaata aattccagtc catttatttc tggcattgtc
    39721 acatccgtta ctactaaatc aatctgtcgc tgttcaagta cagctagtcc ttctttggca
    39781 ttctctgctg ttgctactat ttgaaagcct aaactttgcc aatcaattat cttttttaac
    39841 ccattcaaaa tcatgtattc atcatctacc aataacactt gatacacgct catccctcct
    39901 tgaatgtaat agaaacggtc agtccacctg tctcattatt ctcaagcgac atataataac
    39961 tgctgccgaa gctggcacgt aaacgttcat tcacgttttg cagaccgata gaaccgtgaa
    40021 gttccacttt aggatgagac agtttttctt caatctgttt tagccgtttt tcagtcatcc
    40081 cttttccatt atctttgatg atgatcctta cccgtttgcc ttcctgcaag actttgacac
    40141 ttagcgcatt atcgaatcga gtaaaatcaa taccgtgttt aaaataattt tcaactaatg
    40201 gctggatcac aaatttaggt acttcgatct tttccaaatc aggatcgatc ataaaatgat
    40261 aggctactcg attaggataa cgcatttgat acaaatagac atatttttcg caaaagtcca
    40321 gttcttcttt taaagtgatc gttttctctt gattcgtatt gtttcgaagc aaagcggaaa
    40381 acgcatacac aacatctgct aattcttcac ttccttcgct gattgcatac attcggatat
    40441 attctaatgt attatataaa aagtgtggat tgatctgtgc ttgaagcgcc cgcatatgtg
    40501 cgtcttgctg tttgatttct aatttgtaga tgtcttctac aaactgattg atgctatcca
    40561 acatttcgtt gataccgatt gaaagttcct tcagttcata ttccgtgttt gttatgtcga
    40621 tccgcgtctc taaattccct gctgctgttt gatccatggc ctgcatgacg atagatactt
    40681 gctgtgaata tcgtttgaat gttttataaa gaaagataag cagtatattg tctaaaataa
    40741 tgataccaat gatcagcggg gcaagatttt ttcccgtttc gatttttaca ctttttttat
    40801 ctagtacagc taatatacga taatcatcag acagttcttg gtgttgaaca aaattgtttt
    40861 tttccagatc gtcaatcggc aattgtgaat ttttcttcag actctctgtg atgatcattt
    40921 cttgtctttc aaacgtttct ttagctattt tattatcatg gaatgtgtat agtcgatttg
    40981 tcgttccaga aatcatgtat aaagagagtc cattgaatga cgttagattt tctaaaatca
    41041 tatctagttc tttcttttga aaaccaataa aaatacttcc tgactcagct cctccttgtg
    41101 tgataggcaa cttgatataa aaggcgtcta gtaattttgg tgtccccttt tttatttccc
    41161 cacctttgtt ttctctagaa gattcataat actccggtag ttgattcaac acgatatata
    41221 tcgcacttag ttcttcataa tttgcgtaga gatctttgat ttgatttggg aaagaaacta
    41281 attcatcggt actgttttgc tgttcgtata catacatcag atactgatct atgggttttg
    41341 ttaagtaggt cgtcacattt tcgatctttt cggaattccc tacaagctgg tttttgatga
    41401 tcctactcaa ggttgtttta tcattcagca ttctgcttgt gctttgaacg gcatcacttg
    41461 tcatgttttc tgcctgtttt tgattttgtt cccaagtatg gatactaaaa ataacggtag
    41521 cagtcatcgt tacaccgatc atgataaccg cgtatttccg caacagacga tttagtaagg
    41581 ttccttttga aaatagaatc cgaaacttat tcataacttt ccaactgttt atctaattct
    41641 tcacgccaat gtgttgtcat cgtaccattc caaaccgtca aaagaccaat gacaccaaac
    41701 aggatcaatc ctttgaattg ccaagtcacg cctaaaatta taccgctacc aataattatt
    41761 tttagaaaag acgaaaagct ggaaaaaacc gaaataaaac ttagctttag cagattagga
    41821 acagagatcg tatattcact atctaaaatc atactgtatt gataagtagc aaataggcag
    41881 agcaaggcaa aaagtaaaat aaaatcaata gctaaaaaaa tgagcccttt gatttgaaca
    41941 gataaatata aattgtaact caataaagca gtaccagata aaaataaact aaatagcaga
    42001 ttgcctctta aaaaatttct tttatatata ttccagcctc tttttattgt gatttcttta
    42061 tactcgaatc cgtacaaata aaatagttca ttgactgttt tccatgccgc acctaatcca
    42121 aagatgatcc cgccggcaaa tgtatatatc cagaaataca aggttagttt tataatgacc
    42181 cagatccgga taaataactc ttccaaaacc ttccctaaca tatcttctcc tccaaacatt
    42241 aagtttatac tttctcatta tacaaaaaaa ggttgggcaa tcagcacctt gacctgatta
    42301 ttagagaaac aaacggaaaa atagttcctc atattttgtc gttttgtgag cgaataccga
    42361 gggttagctg attgaacacc gtttaccaag agtttgtgaa atagccgctt agtttcgagt
    42421 agtaagaaaa attttgtgaa tatggctttc cacattttta catatattta gcttaatacc
    42481 gagaaactgg cttttgaaca ccgtttattc ggaacaagag gttgtgacac gtcttttgtc
    42541 acaacccctt tgtctttatt cattattatt cttgtcggaa ctcatcatat tgtttttgca
    42601 tttctttcaa taccttatca tagccagcct tgtccaaagc gtctttcaat ttcggtaatg
    42661 tttcatctgg atcaacagtc cctgtattca atccatctaa atattgattc atgacattag
    42721 aaatattact taattctgtt ttgacactgt cagtgttgaa gctgaatcct aaaatcggtg
    42781 aagtttctgc atcagcaatc gattgatcac gtttggcaat catgtcatcc gtaatagact
    42841 cttgtgtata tagaatcttg ttgtttcctg tattccaagc agacatatgt gtatttggct
    42901 gataaccatc tagcaatttg attttatcat ctgaaccatc gactttttcc catgcttctc
    42961 cctcgatccc ccaaacaagc ccattcaata attctggatc actgttaagc agccctagaa
    43021 gttctactga tttttcttta ttttttgaag tatttgatac gacaaaattt gccatttgtg
    43081 cttgagctgt agattttagt ggaacagtaa ttgcttttga gacaagttct tgttttgctg
    43141 catttgtcaa aattgtatcg ccataatcat acggtccttg tgtttctcca cgcattagcc
    43201 aagtatttcc ttctagtgga taatccttat tgctcgttgc agcgtcactt ggaatgagtc
    43261 cttgtttgta ccagctatgc attgtacgta acagtccgat atacgtttca ttatcgtatt
    43321 ggttgatgat tttcgaatca tctccatcca gatcaatagc aaatggtaac gtattcccta
    43381 aaggataatc aaagttccct tggactttga agccttgtcc aatggcaaaa gctgccgtgt
    43441 ttggttcttt ttcatggaat tccttcaaga ctttttctgc atcagcgtaa gattggattc
    43501 catcaattga aagatcgtat ttatctagta aagctttgtt aaaagtaagt acttgttgag
    43561 caaagacatt tccattgact gggaaagcat ataattttcc attgaccaga tttcctttaa
    43621 tatatgcttc atctaaatca ttataagctt tttcagcgta cttaggcgct aattcagtca
    43681 aatcagcaaa ggctcctttt tgggcattgg aaacatagtt gttcgcaaag gcgatatcat
    43741 aattttcccc ggaagaaatg atgacgttca ttttcttttc gtaatcgccc cagccaatgt
    43801 aattgatatt gacttttaca ccgatctctt tttcgattcg tttgtttgct acttccatca
    43861 attgatcgaa attatctggt ttatctccga tttgatacat ctgcaaagtg tccgaattgc
    43921 tagcttctgc ctggtcttta gaaccagaac ctccgcatgc tgctaatgtt cccaacaaca
    43981 acgctgaaac acctgtaaag gctagtttct tccataactt catttttctt cctcctaatt
    44041 ttatgattta tatttttgtt tctttattct tttactccgc cgattgttag acctttgaca
    44101 aaatgcttct ggaaaaatgg atagctgatc gcaataggca acgtcgagat gactacgatc
    44161 gccattctgg cagattctcc tggaactgag gctaatccgc ctgtcaattg gcttcctgct
    44221 cctgaatttt gtgtcagata ttgaatatta ctttggattt tcatcaaaag atactgtagt
    44281 ggaactagct tatcatcttg gatgtatagt aaagcattga accagtcatt ccagtaaccc
    44341 aatgcggcaa ataaactgat tgtcgcaata cctggaacag ctaacggtaa aacgatctga
    44401 acaaatattc gcagttcgct agctccatcg atccgtgccg attcaataat cgaatcagag
    44461 accgaacgtt taaagaatgt gcgcatcaca ataatattga agggactgac agccattggc
    44521 aagatcaatg cccaaatcgt atcttttaac tgaagaagat ttgtcataac aagataattg
    44581 gccaccatcc ctggtgagaa caacatcgta atcaaacaaa aaacggtaaa aaaacgacgg
    44641 aatggaaagt ttgaccgtga aatcgcataa gcatataaag aagtagccgt gctattgatc
    44701 agtgtaccta aaacagtaac aagtacagtg acgaaaagcg cttggaaaat tttatcctgc
    44761 atctggtcga acaagtacgt ataaccaaat atactgaact tttctggcca aaaactgtac
    44821 ccgtgagtcg acaatatgga ctcatcggta aaagagatgg cgataacaaa tataaatggc
    44881 aaaatacagg aaatagcaaa gagtgcaatc attatattag agaaaaaatt agccgtctta
    44941 ttgaaagagc ggacttggac tctctccact ttcttttttt tcattttttt cctccttaga
    45001 ataatgcaga atcgctatca aaacgtcggg cgatcgtatt tgtgatcatc aacaagacaa
    45061 agccgacaac tgattggtaa agtcctgcag cagccgtcat accaaaatct cctgtggatg
    45121 tcaggccatt gtagatatac gtatccaaaa cttgagtcac atcatataat gcaccggaat
    45181 tcctaggaat gttataaaac aggccaaaat cagctcggaa aatgtttcct acggctaaaa
    45241 tcgttaaaat cgtcattagt ggaataagtt gtggtatcgt cacatgtttg atctgctgcc
    45301 atttgctagc tccatcaacc atagcagctt cataataagt cggatcgatt cccataacag
    45361 atgcaaagta aataatgctg ttataaccaa tccctttcca tgtaccaatg aacaccaaga
    45421 taaacggcca atatttcggt tcattatacc aattgacagc ttctcctcca tgtccagtga
    45481 tccactgatt gaatattcct ttgtcaggac ttaaaaaagc gtaaacaaag taactgataa
    45541 tgacccaaga tagaaaataa ggtagtaagg acatcgtttg ataaacttta acgagtcgtt
    45601 tatttctcaa ctcgctcata atgattgcaa atacgactga gatcagcaga ttcaaaagga
    45661 taaatgctac attatataaa attgtatttt tagtgatgag aaatgcttga tccgaagaaa
    45721 ataaaaattt gaaattttcc caacccaccc aaggactttc cctcaagcta gccaagaacc
    45781 catctgctga aatatgaaaa tttttgaatg ctacgacatt cgccattaca ggtatgtaaa
    45841 agaaaaaaat catccaaagc atacccggta cagccatcag gacaagtgct ttataacgcc
    45901 atagattcat aaaaaaatga ttgaacccct ttcgtttttt catctaaaaa cccctttcga
    45961 ttcattcgca acgtaattat agcgctttca ataatgagaa taaataaaca aagtataggg
    46021 aaaatgaaac aaagtatagg agaggttgtg aaatcagcgt tttggcctga gtattagaga
    46081 aaaaaacggg aaaatagttc ctcatatttt gccgtttttt gagctaatac cgagggtcag
    46141 ctgattgaac accgtttatc agaggttgtg aattcagcgt tttggcctga gtattaggga
    46201 gatcgtgtcc ttactatcta actctgagtc acaaggaaca atggggactg taacaaaagt
    46261 cttgtcacag tcccttattc cgaacaaacg gtgttccaga agtagcttct acggaaataa
    46321 gccgaaattt cacaaaaaag ccatccgaaa gtcagacgga caagtctgct tttcagatgg
    46381 cgctacaact actctgctta ttcttttagc tatccattca attatttttc tctcacttgt
    46441 tctagctctt ctttggtcat gggtcgatat tgccctttat tcaaatcttt aggcagccaa
    46501 aattttccca tacggattct ttttaaatat aagacttctt ttcctactgc tttgaccatt
    46561 cgcttaactt ggtgaaactt tccttcatgc aaaatcagac ggataattga agtttctgtc
    46621 tcttgatcta cttgatcaat ttggagtttt gccggcaatg tctgctcatc gccatcaata
    46681 atcagtcctt ctgcaaataa acggatatct tcttctgtca ttataccgct aacctcagct
    46741 agatattctt tctccacatg ttttttaggt gatagtaact gatgggcaaa caccccgtca
    46801 ttcgttaaaa tcaagaggcc ctctgtgtct ttatctaatc ggccgactgg aaaaagatct
    46861 tcccgataat cctggtcttc caataaatcg attacggttt gatcatgatt atcctgagta
    46921 gcagaaatga ctcctgcagg tttatgcaaa atgtagtaaa aatctttttg atacgtaatg
    46981 atttctccta aataagtaac cgcatcttcg aattcattta cttgcgcttt atcgcttttc
    47041 accacttgtc cattgacttc gatcgttcct tttttgatta atcctttgac ttctttgcgg
    47101 ctgccaagtc ccatatctgc taaaaactta tctaaacgca tgcgtttccc ccatttcaaa
    47161 agagcatcaa tctagctctt ctgattcact tattttattt ttaatttatg tcgtaaacgc
    47221 gctattcctg gtcctagtag tctttctgcc aagcggattt tcaaagctaa ataaccatac
    47281 actaaagccc ctatacctgc tactacaaga atcaacaata gagactggaa tttgctatct
    47341 tcgtttaaaa aagcaccaaa aatcatcttt gtgatccacg aagccaaaag cataatcaag
    47401 gtaagaataa agatcagcaa tgtcctgcgc cagacaaaac ttggtttaaa gcgggctact
    47461 tcatggattc tctttaagat caaggtacaa gacacagcaa atccgatcat tgtcgccaat
    47521 aaagggccgt atacttcaaa taaacgaatg gctgggtatt gaagaaggag tttcactaga
    47581 aacccaataa ccaaataatt aattgccgcc ttgttttcaa acattccttg cagcatgttg
    47641 gaaactagca tatatagtcc taggaagagt cctacaaaac ttgcttggat cagtacatta
    47701 cttcctagag aatccggtgt ataaaataat gtatttagcg gataggcaag taacataaca
    47761 ccaaatgtcg ccggaaacat aaaaaatgaa aacaactgta aatttccgct tgtcaatttt
    47821 gccagaccta ctcgatcttt caacgtaaca gcttctgtaa tcaacggtaa cccagtagac
    47881 gcgatcgatg ttgccaatgc aataactacc atcgtcaact tatctggatt ggcactaaaa
    47941 atcgaaaaaa gatccagtaa ctgtgcattg gaatactcgg tggatgcaga catgatcttc
    48001 ataaaagtga actgatcgac taatttgaag atcgttaccc ctgaacccac aataataaac
    48061 ggaatcgctt ctttaacggt atctaacaac aattccttcg ttgcaatatt tattttgttt
    48121 tcgctgtagt gaataaacgc cgatgtatac gcttgatgtt tcttcaaaaa atacaaaagg
    48181 acaagaatac ttgctagcat accgataaat gccgcgaaag ttgattgcgt gaccgccgtc
    48241 acatagtcac catccatgac tttcatgatg atgaatgtag ccaatagcat ataaaaaata
    48301 cgtgccacct gttctacaat ctgcgacagc gcataaggca tcatttcttg attgccttgc
    48361 aaataccctc gtatcacact catacaagga aaaaccaata cagcgatact caaagaacgc
    48421 atcgttggaa tcagttcttc tccgccacca gaagcatgag ctagccaagg agaggcgatg
    48481 tacatgaaca aagcaaacaa caggcctaac ccgcccatca tctgtaatgc acggataaat
    48541 aatcgtcgtg aagtgccata ttcattcaat gaattatagc gtgcagtttg ttttgcaatc
    48601 gcagcaggta ttcctgctgt agagatcagt agaaacaatg catatatatt gtatcccata
    48661 ttgaataatc cattggcagc cttagcattt tcgcccatcc aagcatacca gggaatgata
    48721 tagacagcgc ctagcaatct tgaaatgata ttactggcgg tcatccaagc agagcctcgt
    48781 gccatttttt cttgcggtgt taattgatct aatgctggtt ttctttgatt atccatcggt
    48841 cagattccaa ctttctacaa aacattacta tcattttaat tggtaaaaca gaaactggca
    48901 atcgatttta tataactttt ataagaacaa ttgttttttt gaattcggtt tcgttttttt
    48961 ggtaaagtaa agaaatatac agccttttat ggctaacatt tataggagat atcaatgaca
    49021 caagaaataa aaaaactacc cgttatattt ttaggtcttt tctttatcac agttggattg
    49081 aattggttct tgctccctca cgatatagct tccgccggag tgggcgccat cggacattta
    49141 gttgaaacgg ccttttctat ccaacgctca gttactgttt ggagcatcaa tcttatgatg
    49201 ctgcttctag ccgctgtcct attaggaaaa tcagtatttt ttaagactgt agcgggaagt
    49261 ctgctttttc ctgttgtttt agagattgtt ccaaaagtgg aaatgatctc ctcacatttc
    49321 ttttcactga tttcaggaag tcttttgttc agtcttgggg tttacacatt gtacacagtc
    49381 ggggcctcaa atggcggtat aacgataccg ccgattattt tccacaaatt ttttcggctt
    49441 ccaatgccgc aaggactttt acttaccaat agtcttatcg tctttttgaa ttattatgtt
    49501 tttggattgt tggagacact attcgttctc ctatctatta cagtcagttc attgtttatg
    49561 aaaatactca tccgcttgtc ccctgtgtca agaaaatttg aataaagctg gattttgtca
    49621 tagcggaaac aaacgatata ttaaaaagag tgtgctataa taaaccaaga aattgaataa
    49681 agcgagggat caatcaatga gcttctcttt agaagacatc cgtcatttac tattaaaaga
    49741 aaatctatta aaagaatttg tttcaacaag aggctggcat cttgatgtac cagaaaaagc
    49801 tgaatttctt cagttaagtt atgattcaag aaaagctgat gcttctactt tgtttttctg
    49861 taaaggaatg aatttcaaag aagaatattt ggattcagca atcgaacagg gtattcaata
    49921 ttatgtatca gaacaaccat acgaaaattc agcagtagga atcatcgtaa cggatatccg
    49981 taaagcaatg gcgcttcttg ctatggcttt ttacgactat ccgcaaaata aattgaaagt
    50041 gatcggattc actggaacaa aaggtaaaac aactgctgcg tactttacaa aagcaatctt
    50101 ggatcacaca acaaataaaa aaacagcatt gctttctact atgaatacaa cgttagatgg
    50161 caaaacatat ttcaaatccc atttgacaac gcctgagtca ttagatttat atcgtatgat
    50221 gtcagaagca gttgaaaatg gtatgactca tctagtgatg gaagtttctt cacaagctta
    50281 caaaacacaa cgcgtatacg gcttgacttt agatgtcgga atcttcttga atatctcgcc
    50341 tgaccatatc agtccgatcg aacatccgac atttgatgac tatttctatt gcaagcgaca
    50401 attgatcttg aattcaaaaa cagttgtttt aaatcatgaa agtgactatt ttgatttact
    50461 tagggaaaca gccgatctat tccagattcc aacgatcact tatggtcgtt cggaagaaag
    50521 caattatcaa gtgatccgtt cagataaagg tactcacggt tttactttat cttctcatga
    50581 agatcgctta gctatctgcg atactgctta tgatattttg ctggctggag gattcaacca
    50641 agaaaatgca gccagtgcga tcattgccgc agcactaaca ggtgcctcca gtcaagatgc
    50701 acaagacgga ttaaaagaag ctcgtgtacc aggccgaatg gatcaattga tccaatccaa
    50761 tggagcgcat gtctatgtgg actatgcaca taattatcta agcttgaaaa cattgctgaa
    50821 atttgccaaa aatgaacatc cagatggccg tgtaattgtt gtattaggca gcccaggaaa
    50881 caaagcaatc tcccgtcgac atgattttgg aaaagtgcta tcagaaacag ctgacatcgc
    50941 ctttttgacg gcagatgacc cagcatttga agatccgaaa aaaatcgcgg aagaaatcaa
    51001 tgaagcaatt actaatccag atttgatcgt tcattatgaa atggatcgtc ctgaagcgat
    51061 tcgacgcgct ttagcagaaa gcgctccgca agattcagtc gttattgcgg gaaaaggcgt
    51121 ggatccctat caaaaaatca atggtgtaga tgaaccttat gaaggggatt atgcaatcgt
    51181 gaagcggttg attgaagaat aatggtattt atatactagt ggtttcccat ttctaagaaa
    51241 aaaagggact gtgatttttt gtcacagttc cttttttctt agaaatcatt ttaacttttc
    51301 actagctaat tctgctgcct tttctctttc ttcatttaat aatttattat catagaattt
    51361 gataaatggg aaccagataa tgaatgcgat gattgcacaa atgactgcta acacagcagc
    51421 tttccaatca ccaccactac caacaaatgc tccgatcccg actggtgaag gccacggcat
    51481 ctgtgcaagc atcggtttga cgatttccag ccgaatggca aaataagcga gtgtagcaga
    51541 agccatcgga gctaagaaaa acggaaccgc taaataggga ttgtagacga ttggcatccc
    51601 gaaaatgatt ggttcattga tattgaataa tcctggtaca agtgaggctt ttcctaacac
    51661 tttcagctga tcagatttcg cgaggaatgc aataaagatg atcaatccta aagtcgcacc
    51721 tgatccacca acggttacat aagaactgtt gaattctcct gccaacggat aatttgcgcc
    51781 ttgtgcgtta gctgccatat tagctaatac gatcggggtc aagaaagaag tgatgatatt
    51841 cgctccatgg atccctacga tccacaatgc atggatcaag aaataaatca ccatgacacc
    51901 aagccatgta ttcgtcaact gcgtaacaaa cccaaatggg atagcaatca ttttgaagat
    51961 atccgttcct agtgcaacta ataatccatt gatgatcatc accacaaacg caatgacaaa
    52021 tgttgggatc agagcagtga aagaacgaga aactcctggc ggaacaacat ctggcatttt
    52081 tatgacccaa tttctcttga cacacataca atacaattcg accgcaataa tcgacataat
    52141 aatagctgta aagattcctg aagttcctaa acgttcgaca aaagagccca tcctaatacc
    52201 atttactaca gtttctgtct cattgataga agcaatcaag ctgattttac catcagtcat
    52261 gatcaattca gggatacaca taaagaatgc aaaaacagat agtaatgccc ccgtgagcgg
    52321 attaacattt aatttttgtt catctcgttc aattgacgtt aattcataag caaacacaat
    52381 ggcaaagtaa atagataaaa tccccatcgt cattgtattg acgatcatgt acaagtcact
    52441 aactttgaaa aaagttgcat taaaaaatcc ttctaaaaat gggaacggta atggcaaaat
    52501 atttaaaacc aaaaacatcg agcctacaat cgtgaaagga atagaagcca tccccgctgc
    52561 catgacagcc cgaacgattt taagttgcgc aattttcccc ataggtccca tcaggtattt
    52621 ctgcaaaaaa tcaaacatta gttattctcc tttcctaaat ataacgcttt ttcatattgt
    52681 ttaatacgga tatactgttg gtcttggttg agtgaaattt tctttaaacg atactgtata
    52741 aatgcactgg caaaaatacc gcttacaaca agaatgaaaa caaataactg tcctccattg
    52801 ttatttgcca taaaaggata caagaatgta aatcctgagg taaacaacac tggaatcact
    52861 aataaattaa agacactctg gaacaaaaaa taccactttg tccatggaac gttcgtttgg
    52921 tgttttcgat aaagctttac ttgttctcct actgcaggca aaatagctaa aatcagaatc
    52981 atcggtaaac tacttcctaa acttttagct gatagaagca gaatcatcca ttgcatgttc
    53041 atgaaaaaga aaaaggcagt caggtaacgt acgattagat aacgattgaa atacatgttt
    53101 ttcaaactaa gttgcttttt ttctaattcg attttccttt ttactgtatc ctgcacaatg
    53161 atccttcctt tctatttatt tttttgatac aaataattca tttcctgtgc aacttccaat
    53221 aatgtcatcg tcgtcatcag atgatcttgt gcatggacca tgataatttc catttctatt
    53281 tttgtcccgc tggcatattc tttcagaagt tgagtttgtg actgatgcgc atgaagaatc
    53341 tcttcatttg cttgtcgcaa cttctcttct acttcttcaa acatctcttt acgcatcgag
    53401 cgaaatgctt catgtatcag tgtccgtgca tttccgctat ggaaaatgat atcaaaagaa
    53461 gtcacttgta gtgtttcact gtttattttt tcagccatct gttttcctcc ttattcgatc
    53521 agtttgataa atttactgct gaaattctca aaaataggtt cagctaagat ttcctgctgt
    53581 acttttagct ggtcaactaa cctaacgatt gctttagtca cgaccgtaat tccttcattt
    53641 tcgacataag aaggcgaaac taaaaaaaca aaatgaattt cttgatattg atcccactgc
    53701 atcccagaag gaatcaatgc aacggctacc tttgtttcga ttccaactgg aacagcggga
    53761 tgtgggactg ccactgtatc actgaatatg atttgtccca tattttcacg ttgctggatc
    53821 tgctttcgca tttctcttat atatccttct tcttcattta tgctcagctt ttgcagcaaa
    53881 tcatgaagaa tttcttcctt tttcggttcg tacgtataag tcttgaaaaa tttttcagac
    53941 aactgttcgg tgtaaatctg ctttttttgc tgtagagaaa atgctggtat cggtctatct
    54001 gaggaatgat agggtataga ttctccaact acctttcgta ttttacgaac atcatcttca
    54061 ttcaaaaaaa tactgacatg taaaactgga attttgaaaa acattgtcga aagatcaata
    54121 gaagaaataa tcaggtcgat tccttttaaa gttgtttcat tgatctcata atagcctttt
    54181 acacttacca ctgtaatatt tttaccgaat tcactgacta cgcgattctt taatagttgg
    54241 gcactgccgt aacccgttgc acagataatc aatgcatgta gtttatgcgc agctctttct
    54301 ttttccaatg ccgccatgag atgcaaagcc aaataggccc attcatcttc attgatggta
    54361 tagtttttca aagccggcat gttgctgaaa tgccttttta ctgcgtcaaa gactttggga
    54421 ttttctttct ttatctcctc agtcaatggg ttctcaatgc gaatacctcg gctcaatcga
    54481 atcatcatcg gtgacaaatg atcgagtagt ccattgaaaa gctggagatc ctctactaat
    54541 gaaaaatgaa attcctgaga caatcttttc agaactttcg ctaattcctt tgatagttcc
    54601 tgatcatttt gattttcttt gtgattcgac ttagccatga gatgtaatgt caaataagca
    54661 atttcttctt cgggaaacga tacacctgcg attacctcaa tacgttgaac gatccgctgc
    54721 gccacttgat actctactcg cttagaaact tcttgttcga tgcctaattc cttgatttca
    54781 aacccttctc ggagccgttt gatccccaaa gccaagtgta aagtcagatt ctgtatgata
    54841 aaatccgaaa cttttaactt agcttctctt gtttcatcga gaatgataat gactagctct
    54901 tcaaaactga tgtctgggaa aaaacggctt tgccctaaat attctttcaa tgaatttcca
    54961 taatggtttc caaaaaaagt atccatgata aaatgccgtc gatttctttc ttccccttcg
    55021 atccatgtcc cttgaccatg cttagaaacg atttttagtg aatatggaat caatcgctcc
    55081 ttgatttctt gcatgtcctt tgtcaaactg gaacgactga tataaagctc ttctgccaaa
    55141 tcatccataa aaagaatggc atcttccaaa agcaattggt tcaatatata cttttgtcga
    55201 tcttcggact cataaaatcc ttgcggttct ctagcatatc caggtactat ttcttgccga
    55261 ctcaaaaaca agtcaaatgt cagtctttgt aaaatatgca gttggtagcc ataacctggt
    55321 ttagcaatga tcttacctcc gtttttttct actaactctt tgatccgctg caagtaatta
    55381 cggattgtcc gatcagataa taacaattca gaagctaaac gttgactggt gacatactcc
    55441 ttcttgtgat caatcaaata tctcaacagc aatttttcct tctgtttcat tatcatccac
    55501 tcctattcca tcatatgttc tcttcgatca cctctgctaa cttctggatg cctgtaggga
    55561 ttgggacata cgcttggaaa gggatactaa caacaggctt tccaacagat tctcctaatt
    55621 ttttgaattt atccaaaaac atcgtcgttt gcgggctgat cagaaataaa tcaaaatcac
    55681 tattcttaat catattatcg ccttctgtag ctgaaactgc atctacgagt acctcttctc
    55741 ttttttgctt aaagaaatcc gttgtctttg aggccatcat cgaggatgac attcctgccg
    55801 cacaaataat caatgctttt ttcataaatc aatcactcct tttattttta taaaccaagc
    55861 atatcttgta agcgttttct attcaaaata tatatttccg tagcattgcg gaaaaaatgt
    55921 gtatcatatc ttgaataata atttctggca ccgtgatata ctagtgatag aattttttca
    55981 ggaggggatt tagtgagtat cacagtgaat attttgtata caagtacaaa tggacaagcc
    56041 agaaaatttg cagaagaaat ggtcgaaaga aacattgtca aagcgattcg tgcagaagaa
    56101 ggaaacgaga aatatgacta ttactttcca ctagaagatc cagaatctct tttactgatc
    56161 gaccgttgga aagatgaaga agcaatcgaa aagcatcaca aatccgaaat gatggctcaa
    56221 ataaacgaac tccgtaaaaa gtataaatta aaaatgaaag tcgaacgttt cactgattta
    56281 ccgtaaaaag atacacatgg aatgatagca atttatcatc catgtgtatc ttcacttttt
    56341 ccttattttt tattcgatct catctaatga ttcaaaccgt gtttttctct tatttttcgg
    56401 ataagtattt cagtcacccc aatatacatg attcctaaac ataccccaag gatattctca
    56461 aaaatgcgga tcgttactgc tcctggaacc ccgaataaac tggcagtgat tgccaaagca
    56521 ccaaaagaat taaaaactgt tttatatcta taggtagaac aaacacctaa agctagacca
    56581 cctaatatac cgacccagtt aaaaggaata aattggctga taccaataaa taaaacacat
    56641 ccaatcaatg agccaatgat tcggtctact gctcgttctt tgaaaccaat cgacatcaat
    56701 ccatagctag atacaataga agaaaatgca aaccctgccc acatcaatcg ctgaaaaggg
    56761 acatactctc ctgcaacgat caaaagacta atgccaaatg catagatgag catccaaatt
    56821 ttttcctgcg aatacatgcc tttcaaaaaa atctctttaa acaagctttt gtctttgttc
    56881 ttttctcgat gttttctgta aaggagaact gaaaaccaac aaaaaaacaa aaataataag
    56941 ctacttgttt gtgtaaagaa attcttgttc aacgaatctt taggtaacga ataaacaata
    57001 aagagatatg aaaagccgta caaagaagca ttccccattt tgggatcact agcggttgcc
    57061 attaatatgc tgcttagtaa aataaaatga atcaacatgc ccataactga ccatttgatc
    57121 agctggacat acggtgctac taatagtgag aacatgacga ttgctaaacc tatgatcgaa
    57181 tgggaaatct tataaccaaa gtcaacaaaa cgaatactca tcaacataca gaataaaacc
    57241 acagcgtatg gtttatgctt cgattcaaat aatgttgtaa ttataatgat aaaacaaatg
    57301 gcaaacaata cgatgaataa tgatcgtaaa aacaatgaac aaatatacat gcacttttct
    57361 tttttagaag ctgcttctcg tattttttgt tttaaaataa acggatctag ttgtagagac
    57421 tgataaaaat ccacctgttg tcgtcctttc tttttacttt tattttttac agtcatctat
    57481 gacaggttgt aaatactatg gaacatcata tggcgttgtc attttcttgt caactatttt
    57541 tcctattcat gtttttataa aaaaacatat cgttttcttg tatgattaaa tcaccacaaa
    57601 ataaacaact gagagaacga tatgctttat gaatggttct atcaaaaaaa ttctgagatc
    57661 aatagacaaa aatttgatga ttacagaggt ctcttacgaa accttacaga agaaaaaaac
    57721 attgatcgtt gctgcagttc tcttccctgc tccatgtgtc tgtagaaatt gtggttctgc
    57781 tgtggtagat ggaaatagga aattaatggt ggtgaaaaac aagaagaagg aaaccattgt
    57841 ccactttgaa taatataatc atatgccaat ggttatacgc ctaaaaaagc agcgctatac
    57901 ctgtaaaaac tgtcgaagcc attggaacgc tcaaagttat tttatccgtc caaggcactc
    57961 gatttcaaat catgtcagac ataaaatcac ttctttactg actgaaaaag tgtcgttatt
    58021 ttttatttcg aaaagttgtt aggtatcttt gacaaccgtt attcgcacat tgaaagagtt
    58081 gagaagctat ttaccaaagt cttccaaaag aattctgtct tgagtgttga gggttgtgaa
    58141 tttcgttctc acgtttccgt tgaggataaa ctgagtttta tttccgcgga tggcgagaca
    58201 gaaaaattaa tcgagaaaat ttacctacac aaaaaattcc tcgattaaca aactatttcc
    58261 ttagctgcac taatcctaaa gaaatagaat tcttagttac agacatgaac gccacctact
    58321 ttcagctcac caaacatgtt ctaccaaatg cgaaattggt gattgatcga ttacttggtt
    58381 tttccacgcc tttcaaggag gcgtaacctt tattcacgag ttggttgaag ctttccgaga
    58441 caaaagaccc gacttgtttt tctccttatt gacaaagagc cattaaaact agagaaaaaa
    58501 ttacaactga tcgctgatta tttgtagaaa gaaaatcaaa gtattaccca ataaacttga
    58561 gtcattaggc aaaaaacact gcgaaactca agaatgattt tcgcagtgtt tttgtatatt
    58621 ttttattaac tagtattact acaaaggttt atttttcact tctcaacgca gcacaaaatt
    58681 gtctttactt atttactggt tgggttcaac cttctctact ccgatactaa tatttgtttg
    58741 tatacccctt ctaaaatcgg tagtttccat tcaattgatg ggtactagtt gattttaaaa
    58801 actatgctta ttcaattttt tattttagct catatatttc gtttctttct aaattttata
    58861 ctgatgaaaa caagtagcac acccaatatt gacaatataa actggctaat gatggtttct
    58921 ccagtttttg gaagatgctt atttccactg cttgttggat tgtttcctct tatatctgag
    58981 ctatcagcaa cttttctatt ctcttttgtt aaaaagatcg ccacttcttg ttctttttcg
    59041 atcttgaaag ttactggtgt cgcatccaat tcataccccg ttggcgcttg agtttctacc
    59101 agctgatatg ctcctggtgc taagccatct atcgccagtt ttccatctgc tcctgtggtt
    59161 agacctgact gcagaacggt tccattggca tcttgtaact caaaaacagc tccttgcagg
    59221 acttctccgc tttggtcatc gatctttgtc aacacgacac cgcctggtgt aagtcgattt
    59281 tctttcgtca attctaccac cgctgtctga cttctttcga tctcaaactc gattggtgtc
    59341 gcatccaatt cataccccgt tggcgcttgg gtttctacca gctgatacac tcctggtgct
    59401 aagccgtcaa tcgccagttt tccatctgct cctgtggtta gac
//
LOCUS       DAFEKH010000011        59069 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.012, whole genome shotgun sequence.
ACCESSION   DAFEKH010000011
VERSION     DAFEKH010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59069
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.012"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            212..604
                     /locus_tag="LP386_000756"
     CDS             212..604
                     /locus_tag="LP386_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBL1918016.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="LP386_000757"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="LP386_000757"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HBL1918017.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3165..4775
                     /locus_tag="LP386_000758"
     CDS             3165..4775
                     /locus_tag="LP386_000758"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HBL1918018.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5067..5936
                     /locus_tag="LP386_000759"
     CDS             5067..5936
                     /locus_tag="LP386_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HBL1918019.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="LP386_000760"
     CDS             6101..7372
                     /locus_tag="LP386_000760"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBL1918020.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /gene="rho"
                     /locus_tag="LP386_000761"
     CDS             7369..8664
                     /gene="rho"
                     /locus_tag="LP386_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HBL1918021.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="LP386_000762"
     CDS             8763..9026
                     /locus_tag="LP386_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HBL1918022.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="LP386_000763"
     CDS             9471..9920
                     /locus_tag="LP386_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL1918023.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="LP386_000764"
     CDS             9977..11395
                     /locus_tag="LP386_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL1918024.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="LP386_000765"
     CDS             11395..12255
                     /locus_tag="LP386_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HBL1918025.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13203
                     /locus_tag="LP386_000766"
                     /pseudo
     CDS             12429..13203
                     /locus_tag="LP386_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
     gene            13350..13715
                     /locus_tag="LP386_000767"
     CDS             13350..13715
                     /locus_tag="LP386_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HBL1918026.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13863..15071)
                     /locus_tag="LP386_000768"
     CDS             complement(13863..15071)
                     /locus_tag="LP386_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL1918027.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15090..15368)
                     /locus_tag="LP386_000769"
     CDS             complement(15090..15368)
                     /locus_tag="LP386_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918028.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15522..16217
                     /locus_tag="LP386_000770"
     CDS             15522..16217
                     /locus_tag="LP386_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBL1918029.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(16659..17456)
                     /locus_tag="LP386_000771"
     CDS             complement(16659..17456)
                     /locus_tag="LP386_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HBL1918030.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17453..18637)
                     /locus_tag="LP386_000772"
     CDS             complement(17453..18637)
                     /locus_tag="LP386_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBL1918031.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18662..19909)
                     /locus_tag="LP386_000773"
     CDS             complement(18662..19909)
                     /locus_tag="LP386_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBL1918032.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20124..21869
                     /gene="dnaX"
                     /locus_tag="LP386_000774"
     CDS             20124..21869
                     /gene="dnaX"
                     /locus_tag="LP386_000774"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HBL1918033.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21889..22203
                     /locus_tag="LP386_000775"
     CDS             21889..22203
                     /locus_tag="LP386_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HBL1918034.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22228..22824
                     /gene="recR"
                     /locus_tag="LP386_000776"
     CDS             22228..22824
                     /gene="recR"
                     /locus_tag="LP386_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HBL1918035.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22888..23532
                     /locus_tag="LP386_000777"
     CDS             22888..23532
                     /locus_tag="LP386_000777"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HBL1918036.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23547..23876
                     /locus_tag="LP386_000778"
     CDS             23547..23876
                     /locus_tag="LP386_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HBL1918037.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23890..24828
                     /gene="holB"
                     /locus_tag="LP386_000779"
     CDS             23890..24828
                     /gene="holB"
                     /locus_tag="LP386_000779"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HBL1918038.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24864..25688
                     /locus_tag="LP386_000780"
     CDS             24864..25688
                     /locus_tag="LP386_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HBL1918039.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25681..26028
                     /locus_tag="LP386_000781"
     CDS             25681..26028
                     /locus_tag="LP386_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HBL1918040.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26097..26969
                     /gene="rsmI"
                     /locus_tag="LP386_000782"
     CDS             26097..26969
                     /gene="rsmI"
                     /locus_tag="LP386_000782"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HBL1918041.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27078..28199
                     /gene="dinB"
                     /locus_tag="LP386_000783"
     CDS             27078..28199
                     /gene="dinB"
                     /locus_tag="LP386_000783"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HBL1918042.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28253..28855)
                     /gene="nrdG"
                     /locus_tag="LP386_000784"
     CDS             complement(28253..28855)
                     /gene="nrdG"
                     /locus_tag="LP386_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HBL1918043.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29170..31359)
                     /gene="nrdD"
                     /locus_tag="LP386_000785"
     CDS             complement(29170..31359)
                     /gene="nrdD"
                     /locus_tag="LP386_000785"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HBL1918044.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31658..32452
                     /locus_tag="LP386_000786"
     CDS             31658..32452
                     /locus_tag="LP386_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1918045.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32442..34484
                     /locus_tag="LP386_000787"
     CDS             32442..34484
                     /locus_tag="LP386_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1918046.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34765..34914
                     /locus_tag="LP386_000788"
     CDS             34765..34914
                     /locus_tag="LP386_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HBL1918047.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34925..36439
                     /gene="dltA"
                     /locus_tag="LP386_000789"
     CDS             34925..36439
                     /gene="dltA"
                     /locus_tag="LP386_000789"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HBL1918048.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36436..37641
                     /gene="dltB"
                     /locus_tag="LP386_000790"
     CDS             36436..37641
                     /gene="dltB"
                     /locus_tag="LP386_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HBL1918049.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37686..37919
                     /gene="dltC"
                     /locus_tag="LP386_000791"
     CDS             37686..37919
                     /gene="dltC"
                     /locus_tag="LP386_000791"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HBL1918050.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            37922..39190
                     /gene="dltD"
                     /locus_tag="LP386_000792"
     CDS             37922..39190
                     /gene="dltD"
                     /locus_tag="LP386_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HBL1918051.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39331..40413
                     /locus_tag="LP386_000793"
     CDS             39331..40413
                     /locus_tag="LP386_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HBL1918052.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40413..41216
                     /locus_tag="LP386_000794"
     CDS             40413..41216
                     /locus_tag="LP386_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBL1918053.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFVFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41286..42026
                     /locus_tag="LP386_000795"
     CDS             41286..42026
                     /locus_tag="LP386_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBL1918054.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42037..43041
                     /locus_tag="LP386_000796"
     CDS             42037..43041
                     /locus_tag="LP386_000796"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBL1918055.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43086..44930)
                     /locus_tag="LP386_000797"
     CDS             complement(43086..44930)
                     /locus_tag="LP386_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918056.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
     gene            45142..45660
                     /locus_tag="LP386_000798"
     CDS             45142..45660
                     /locus_tag="LP386_000798"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBL1918057.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            45788..46471
                     /locus_tag="LP386_000799"
     CDS             45788..46471
                     /locus_tag="LP386_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HBL1918058.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            46780..46853
                     /locus_tag="LP386_000800"
     tRNA            46780..46853
                     /locus_tag="LP386_000800"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:46814..46816,aa:Arg,seq:tct)
     gene            47012..47371
                     /locus_tag="LP386_000801"
     CDS             47012..47371
                     /locus_tag="LP386_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HBL1918059.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            47494..49125
                     /locus_tag="LP386_000802"
     CDS             47494..49125
                     /locus_tag="LP386_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HBL1918060.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(49187..49828)
                     /locus_tag="LP386_000803"
     CDS             complement(49187..49828)
                     /locus_tag="LP386_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBL1918061.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    50014..50090
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            50110..50418
                     /gene="rplU"
                     /locus_tag="LP386_000804"
     CDS             50110..50418
                     /gene="rplU"
                     /locus_tag="LP386_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HBL1918062.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            50445..50789
                     /locus_tag="LP386_000805"
     CDS             50445..50789
                     /locus_tag="LP386_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HBL1918063.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            50802..51095
                     /gene="rpmA"
                     /locus_tag="LP386_000806"
     CDS             50802..51095
                     /gene="rpmA"
                     /locus_tag="LP386_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HBL1918064.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            complement(51188..52336)
                     /locus_tag="LP386_000807"
     CDS             complement(51188..52336)
                     /locus_tag="LP386_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL1918065.1"
                     /translation="MAMIKQYKKKNGEKAWYFKTYLGIDPLTGKKKYTTKRGFRTQKE
                     AKTALSRLELELQKTGMPTSTNTTFKEAAELWLESYKKTVKESSYSRTKIIFNKHIYP
                     KFGNIKLSKINTAYCQKVVNDWSEKGTSKQYPLFINYMNKVFKYAINIGLTSDNPTLN
                     LLIPKPQIKTEKKLKLYTKEQLELFLNEVSQEQNPYFKNRDYTLFRLLAFSGCRIGEI
                     LALTWDNINFKTNEMAIKKTVARSDKYYISETPKTKKSNRIIYLDEKTIKQLKFWKLE
                     QRKYLFQLGFTKANYLFTNDENNFTINQSVAERYNIYRERAGLPYIGLHGFRHTHASM
                     LYEAGADHKEVQERMGHANIKTTMDTYTHITNSKKEETTQKLTNYINF"
     gene            complement(52348..52659)
                     /locus_tag="LP386_000808"
     CDS             complement(52348..52659)
                     /locus_tag="LP386_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918066.1"
                     /translation="MIYTEFKEWLEKSTTGYETFIIKATNYQIEKNKNRPQKKRWDDK
                     KIDKAVLEMWKQVVTNLYQTIRKEKGVPLINGKEIWLEFIEEQGLIEFFNDSMAELEF
                     E"
     gene            complement(52712..53107)
                     /locus_tag="LP386_000809"
     CDS             complement(52712..53107)
                     /locus_tag="LP386_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBL1918067.1"
                     /translation="MIINELGVKVEERENLDADGHYVACMNTIVIKANLSKYRRQRTL
                     LHELGHASKHHDNYFLYNLAFSLHSKMEYEADRFMIEKLLDRYIAKSELEPHNINYMK
                     FIEDNNLSVRFEPLVKELLKARIYCYAAL"
     gene            complement(53143..53487)
                     /locus_tag="LP386_000810"
     CDS             complement(53143..53487)
                     /locus_tag="LP386_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1918068.1"
                     /translation="MLFERVKELCKKRGISISELENRIGFGKNSIYKWKTQSPKIETL
                     QKVADYFHVSTDYLLGRTDDPNAGVAPEERKLTVEEALASVMSSDGKPLTDNDREILS
                     AMIEAYLEKKDN"
     gene            53788..54009
                     /locus_tag="LP386_000811"
     CDS             53788..54009
                     /locus_tag="LP386_000811"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918069.1"
                     /translation="MKQNKKTPSAKGALITLNFKDQKFSAVVDEIHPQEHQKNSFATD
                     EKKTQKRSEKVLRIIQFLLEKIRHFGSLF"
     gene            54136..54912
                     /locus_tag="LP386_000812"
     CDS             54136..54912
                     /locus_tag="LP386_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HBL1918070.1"
                     /translation="MNTPQIFNFEQHEVRTVTIHDEPFFVGKDVAKVLGYQNGSRDIN
                     RHVDVEDRQNYQNGTFESPRGLTIINESGLYSLILGSKQPNAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATKLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMRQGYTKSHTTEIPK
                     SDGGTKVVMNTKWTQKGRLFIYESLKKEGYIPEIDLLEEE"
     gene            54915..55103
                     /locus_tag="LP386_000813"
     CDS             54915..55103
                     /locus_tag="LP386_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1918071.1"
                     /translation="MSQEFILKVRIQLAKYGKSQNWLADTIGISRPYMSDIMNGRRKP
                     DKQIKPIEAALAELEKEK"
     gene            55105..55389
                     /locus_tag="LP386_000814"
     CDS             55105..55389
                     /locus_tag="LP386_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918072.1"
                     /translation="MQITIPDNLVVSELTTQITNAVLNSLDERLHLMNKSVELPPYPN
                     KSEVKKVLGIGDDKLTHWISLGLKTQQWSKLDIRIERSELQRFLKENFEF"
     gene            55410..55598
                     /locus_tag="LP386_000815"
     CDS             55410..55598
                     /locus_tag="LP386_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918073.1"
                     /translation="MSYTLQQEHQILGLIKQRRKQLQDDRAALRKSDELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            55924..56163
                     /locus_tag="LP386_000816"
     CDS             55924..56163
                     /locus_tag="LP386_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918074.1"
                     /translation="MENELSTLDQYLADPDWGKSNLQLVANKYEKSIDEAIVALTDAA
                     SITADDSKWTKRDLGILKRGVNWLEDQYREETKEK"
     gene            56169..56855
                     /locus_tag="LP386_000817"
     CDS             56169..56855
                     /locus_tag="LP386_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918075.1"
                     /translation="MFKPLIDSYSAVLKKFKGNDIGATINEEVNIERLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGREISLK
                     DESNTTVSDANILANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
     gene            56858..57688
                     /locus_tag="LP386_000818"
     CDS             56858..57688
                     /locus_tag="LP386_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HBL1918076.1"
                     /translation="MAEISWIKLKTTMFDDEKIRLIQAVPESDAIIVIWIRLLVLAGK
                     TNDDGLIYIQRNMPYTEEMLATLFGKNVNTVRLALTTLANFNMIDLSSDGLIAISNWE
                     KHQNIEGMDKVRLKNAERNRKYRERKRQERLKLENDVSVTSRDGTDKDIEEDKDIDKE
                     EKKGKYSDEHLRLAKKLQSNLTEDFPKEMNKVDIEKWADTIRLMEERDKASIEAIEYV
                     INWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKKNHKKQSQKLQYSNPSEYDDLPI
                     "
     gene            57705..58556
                     /locus_tag="LP386_000819"
     CDS             57705..58556
                     /locus_tag="LP386_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL1918077.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALEKAKSYTNEVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNTELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            58553..58912
                     /locus_tag="LP386_000820"
     CDS             58553..58912
                     /locus_tag="LP386_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HBL1918078.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQA
                     PLILAKKYRNTFKEERF"
     gene            58927..>59069
                     /locus_tag="LP386_000821"
     CDS             58927..>59069
                     /locus_tag="LP386_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBL1918079.1"
                     /translation="MTTEEVIQMRIRNIQREIDDLERTKAVMVNETARKAIDLHIENL
                     RRE"
BASE COUNT        19190 a        10123 c        12125 g        17631 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aaagctttta gaaaacaatc agaccggctt gccgttttag ttacacagca aaaaattgca
    13081 cataaattca tgcatcaagc cattgctttt catgaaatcg attatctggt gacaagtaaa
    13141 gaactgacaa aagaacagta tgcgaaagta aaggaacacc atatcgaatg tctgtacgga
    13201 taaattatta cgtgaatgtt ctaagtggct tcctcatttt tagataggac cttatctttg
    13261 ctcgcttttc tcagccgatg gtataataat gaaaaggtta tcttgttaga taatcttact
    13321 tttttatcca ggagaaagga gtgcagaaaa tgaaacatgt gaaggcgttg gtagtgaagg
    13381 caatcatgat ctgggcgatt ctgtgggtcg tgctgacagg tttatacggt gttagcttta
    13441 tggattcaac gattgttggg gtaattattg tagtcatgat ctatgtgcta ggggatctgt
    13501 tgatcttacg taaagtaggg aacatcgcag cgacgatcgc agatgctggt tcagctgcag
    13561 ttatcttgtg gctctatcta tattttatga atgatacagt cgatatttgg atgaaagtat
    13621 tgattcctgc tctattgatc ggtgtggcag aatggttctt ccacaagtgg ttgctaagtc
    13681 aaggcatcgt accagatgaa cggaaaatgg aataaatcaa cagttaaact attcttatcg
    13741 ataaatgaaa gctttaaaaa taaatagatg tttaattaag aataatcata aactattttt
    13801 actcaaaaaa ccgctcagat tattttcaga tctgaacggt tttttttatc tattcatcaa
    13861 gatcaaattt catttttcaa tgattcaatc aattcgccct ctgcttcatg actatgtttt
    13921 cggccattaa caagatagag tgctgtacat atcaatggaa tgactccggc aatcacatac
    13981 aatcctctaa atgaagtaag agattttagc atccccatca aataaggacc aacgcctaag
    14041 cctaggtcta aaccaataaa gtaggtagat aaagcaatac tgattcgatg ttcgcggacg
    14101 atttttaaac aaacagcctg tccatttgac ataaacgtac cataacctag gccgactaat
    14161 gctccagaga taagcaatgt cacactattc gtcgttacac tcagtaaaaa taatcctgct
    14221 gttaagaata aatagctagg atacatcacg tattgttctc ctttgacatc gaaaatcctt
    14281 ccagtcaatg gacgtgtaaa tgtgatgacc aaagcatata cgacgaagaa aaatgaccca
    14341 gcagcaacta agtggattac ttttgtataa gaagataaaa atgataaaac acttgaataa
    14401 gaaagaccca tcaaaaaggc aattcctgta atgaaaagtg ctttcttttc aataaaacta
    14461 ttgatattcc atgagcgaag agatattttt tgttcttcag ataatggaat attttttaca
    14521 ggaaagacaa ggcaggcaat cgtaacaaag aagaccagta caattgaaaa ccagataatg
    14581 aaacgaaaat cagtcatatt cagcaaaatc attcctaaaa atggcccaac agcggcagct
    14641 aaactagtac ttaatccata ataattgatg ccttcccctt ttttagatgc agggatatat
    14701 gcagtaacga tagcatttgt agctgtagaa actgtaccgt agccgaatcc attcaagaat
    14761 cgaactaaat acaatgcccc gatagttggc gtataaagat atgctaatgt tgaaaggaga
    14821 tagaagatcg cgccgcctct taaggtaaac ttccgaccaa atagttctaa ctgtttcccc
    14881 atgaataagc gtgccagcaa tgttccgatg atatagatcc cagaagcaaa acctgcttgg
    14941 ctcaagctgg cgtgtaaggt gtcttgcgca atgactgcca tgatgaccat caacagataa
    15001 taaatcaggt agacaataaa attgatcaat gtgattccaa taaaatattt attaaataat
    15061 ttcttttcca tgtatgttat acattcccct taagctgaat atgcttttaa tttttgtatt
    15121 tgaacttcta catcgtgata attggatgga tagcgatcaa caagttggcg aataaataaa
    15181 tctcttgtag acataaacag atttaaaaat tcttcgcatt cgtttgttgg attctcatcc
    15241 actgctttga tcaattcgat cgagttttga tacgcatcat ttaaaaagac taaagaagct
    15301 ttcatatcaa atcttgtttg atatgctgtt tctaatcgat taatgattgt gttcatccag
    15361 taattcatgt tttttccctc tattcttaaa aaattttact tctgcagtat aacgaataaa
    15421 aaaaaggaaa aaaatcgcat aagtgatgga aaaaggtact taacaaatgt taatatcatt
    15481 agtaaaatac ctttggactt taaaaagttt taaagtactg tatgatcttt ttagatgaaa
    15541 gtttggatgg gggagcatca ttggatagta gagtcttaaa ggaatatttg gataaaaatg
    15601 attttccgat tatacgcaaa ggatatcata aatatttgac attcgaaggg atggaagatt
    15661 cccatacgta tatcttgaaa gagggaacgg taaaagcaag tgttatttca aatgatggga
    15721 gagaatttaa ccttcgctat atcaaagatc ttgaaatcgt ctctctttta aaagacgaat
    15781 attcacaatt catcgattcg ccgtataata ttcgagttga atcagaatat gcagagtttt
    15841 atcgaatcaa tcgtgtgcgc ttttggcaaa atatcaacca agacccaaag ctacaacact
    15901 atgtaaaaga gtattaccgc tatcgtctgc tttattcgat gaaaaaaatg cagcaaatgc
    15961 tattaaacgg aaagctggga gctgtttgta cgcaacttta cgaattatat gatttattcg
    16021 gtgtgcggac agaagaaggg atgctgatcg atttttcgat cacgaatgaa gaaatcgcca
    16081 aattttgtgg catctcaact gctagcagtg taaacagaat tttaaaacaa ctgaaaaaag
    16141 atggtattat caccgttaaa gaccatcata tcgttatttt gaatatggac ttgttagaag
    16201 acaatattat cttttgatga acaaagaggt tgtgaaatca gcgttttgac ctgagtatta
    16261 gagaaacaaa cggaaaaata gttcctcata ttttgccgtt ttttgagcta ataccgaggg
    16321 tcagctgatt gaacaccgtt taccaagagg ttgtgagcct gccgtttaac tctgagtcac
    16381 aaggaacaat ttcaaaaaac agcttttcat gtttgatgaa tattgtgact tgtgaccgag
    16441 gagttggtag gagaacaccg tttaccaaga ggttgtgaaa aagctgttct gcatcaagta
    16501 ataagaagag ccaagtaaaa acagtctctt atgtttttaa cttggctgga cttatcaccg
    16561 tagatgtaag cttttgaacg ccgtttattt gcaacaaaag gggctgtgac acgatttttg
    16621 tcacagccct ttttttgcga acattcattt agcaattttt agaaacttct gccgccaccg
    16681 ccaaaagtcc cgccaccgct agaatgggta gtacttccgc caccgccgct tccaggaggt
    16741 gggcttttgg ggattcttct tgtcgtgaca aaagaatttg tcagacgatc ggttttttca
    16801 gttaatttga tactggattt ttctcggaat ggatatttgt agatgcctga tttcaattga
    16861 taacgcgaaa cagtcacaaa ataaaagaca agactaagga taagagccaa aacaacagca
    16921 atgatgattt ctactgtcgt caaaacctta tagcgtgtaa ttttgccagt ttcttcgtct
    16981 acacgataat gtcctcctgg aactccgtct tccacatatg ttgctgattt agacaggtaa
    17041 gcttttgcag cattgtaata ggcagcattt gtcatctgat cataaacatc atctaagatc
    17101 gaatcgattc tgctatcagt caaataatcg atcatattac cagaagtcga aatgtagatt
    17161 tcacgctgtc ccatatctaa tagcaatact gagccatttt gatcatttcc gactgcgtct
    17221 cttaagtaat tatcagcaaa gtctcttggt tcttctgaat tagatgtagt cgttacgatc
    17281 aagactcgtc ctttgatttt ttcattcagc ttttctgcct gttgttccaa agattggatt
    17341 tgatctgttg tgaataaccc agcctcatca tttaccgtag ctgtatctgc atgagtagcc
    17401 accggccagc caacacttac tagcaaaaga aagaataaaa aaaatttttt catcatatca
    17461 agtaacctcc gatcagaaag aggatcgcta gcccagcgaa aatcccaaga gcggtcagtc
    17521 ccaatttttt ctggctgatc ggcaggacac cgctgacctt tcctgtttgt ccattcattg
    17581 cgtagtagta gactttttta cttgagtcat tgcttcgata agtaacaagc cataccggca
    17641 gtaatacgta attatttact tcgtttgtga ttgaagcaga agttcgcaca ccggtcaatg
    17701 ttgtatatcc atttgcggta tcttttaaca gcttctctga atagtctttt aattcagatt
    17761 gaatctgtga tttgattgcc tcatattcga tatctctttt ttctgcttgg aacccggcta
    17821 aatactggct tttaaaatca attgctttat ctaacgggaa aggttgcacg ccttcgacca
    17881 tcttttgttg cgtatttttt gataaggcat tttttactag ttctttaaaa gaaagcttgc
    17941 ctgctcttga aacagcaaat tgcttcgttt ctgtgtattc gatgtcacct atccgccata
    18001 tgcggataac tgtaccattc gcctgcatgg caccatctac ttcagcatct gtagcccaat
    18061 aagggaaata cacacctgtc aacttatcga tttgatcctt attgaaaaaa gctttgggaa
    18121 caaaccattt tttcttggtc caagcgagaa atctgttgat tgcttcttct ttctcgacag
    18181 caaaaggaag tactttattt ggcaagaatt ctccgcttaa acgtcccgat agtacgacgg
    18241 gattatggca gtagtaacaa taagtcgcag cagttgtcgc atcagtcacg atctctgcac
    18301 cacagttggg acaaagaaaa agatctatcg ctgcggtatt atctgcagat tcgtccgctg
    18361 tatctgaaaa accgcctgcc tcgtcaaccg ctttgcgctc ggcttcattc atatcggcaa
    18421 gctgttcttg ggctgtaaaa gtaaaatctt cggtaggtga aggttcttct ttgctttctt
    18481 cgccagccat acgcgcttct ttttgctttt gctcatattg gctgacttct tcttctgtat
    18541 agatattcag gcagtattcg caatgaaatt tttggtcttt gggatcaaaa gtcaacggac
    18601 cgccgcaatt aggacattta tgtgtaagaa catccatcag ctgcacacct ttctaaataa
    18661 attaattaac ggggattcct ttaaacggtt taccacagtt tggacagaat ttagggatgc
    18721 cgttggaaag atccacgatc tcattgcatt cactgcatcg catttgtagc ttaggctgaa
    18781 cgttttctac aggtttggca gctccgcagt tggaacagaa ttttccggaa ttttctgtcc
    18841 cgcaaactgg acatgtccaa gtatccgcat ttccttgtgc agtttgttga ttttgttttt
    18901 ctgcttgttg tttgatttgt tcttggttat tttgagctgc ttgagaaaga taagaaccat
    18961 ttgcattcat tcccatacct acacccataa agccggtcat tgctcctgct tcattttttc
    19021 cggctgcttc cataccacgt gcaatggaac cttgcacgta tccttcacgt acgctaggat
    19081 cacctagcat cgccccttcg ttacgcatat tgatcagttt cacagaatca tcggtgtaag
    19141 aaatgctggc tacagccaca gaaacaatct ccatcccacg taattcacgc caagaatcat
    19201 ccaatgcagt atccatgtat ttgcttaatt ccaaactctt agatggtaca taagaaatcc
    19261 gttgaccatc tgcagacatc tgattgattg ctgattgtag cgctgttagg aattcagcta
    19321 aatactgctc attgatatca ttgatttcca cttgtgtttt gtttttaggg attgcgtttg
    19381 tataaaataa aatcgggtca acgacatgaa tagaataagt gccatgtgcc cgtaagaata
    19441 attctgcgtt atagaaattg tcaaagtagt tcaacggcgc gcttgtaccg aatttgattc
    19501 cctttatttc ttggagattg atataaaaaa cttgttgttt ctgcggtgtg acgccgccaa
    19561 atttgaatcg gtcaaaagtt tcagcaattg cttctttcag tgttccattg aacatggaag
    19621 gagctgcgtc atttttaatg gtgtaataac cttcctcagc ggtataatcg atgatttttc
    19681 caccatcgac caaaagcatc atcatgtttg gatagacatg gacgactgtt ccgtctgtta
    19741 aaacatcttc tgttccttta cgattggagc cacgtttgtc atctttgcgg actttgacac
    19801 cttttgtcat gaccgttgta tcactcatat tgtctggttc gatgacttct agccattgat
    19861 ctgccagacc gccgccaacc atacttgttg ctgctttgat aagacccata aaaaattcct
    19921 cctctgattc agctagtgcc aaacaattat tgtttattta ttataccata ggaagatgtg
    19981 aaacttctcg gactagagac ggaattgaaa tggaaaattg cgtattgttt aaatacctga
    20041 aaaagccgag aaggatagta gtttttttac ctaatatcac gtataataag agatagtgaa
    20101 tttttaaaaa aagggggatc cttatggcat atcaagcact ttatcgagtc tggcgttcgc
    20161 agcgtttcga agacatcgtt ggacaaaaag ctgtgacaca gacactaaaa aatgctattg
    20221 tttcccacaa aacctcacat gcctacttgt ttacaggacc cagaggaacc ggaaagacga
    20281 gtgcagcaaa gattttcgca aaagcaatca actgtccgaa cagtaaagac ggtgagccat
    20341 gcaacgaatg cgaaatgtgt cgatcaatta ctgctggtac gcaagaagat gtgatcgaaa
    20401 tcgatgctgc cagcaataac ggagtcgaag aaatccgatt tatccgtgat cgggcaaatt
    20461 atgcgcctac aaaggcagcg tacaaagtgt acattattga tgaggtacat atgctttcaa
    20521 caggagcttt caatgccttg ttgaaaacat tggaagagcc aaaagaaagt gtcatattca
    20581 tcttagcaac gaccgaacct cacaaaatac cagctacgat catttcacgg actcagcgat
    20641 ttgattttaa acggatcaat acggcagata ttgtcgaaca tcttgaattt atcttgaaag
    20701 aatcgactat cagctatgaa ccagctgcat tgaatgtgat tgcccgttct gcagaaggcg
    20761 ggatgcggga tgcattgagt attcttgatc aggcaatctc gtttagtgaa ggaacaatta
    20821 ctttagatga tgccatgcaa gtgacaggta gcttaactga cgaaatgatg gacagttact
    20881 tgagtgcttg cgtgaaaaaa gaagtaccag aagcattgga aacattgaac caaattctcg
    20941 cagccggcaa agaatcacgt cgctttctag aggatatgtt acaatactgc cgtgacttgc
    21001 tgatgtatca gcaagcacct aacctagttg aggaacaatc gagtacgatc agaagtacat
    21061 ttacagaatt ggcacaaact gtttcagcgg atcagctgtt ttcaatgata aagattttga
    21121 gcgatactca aaatgaaatt cgttttacca atagtgccgc tatttatttg gaagtcgcta
    21181 cagtcaaact tgcacagcta ccgtctgctt ctgttccttc agcagatgta gcatttgcag
    21241 atgatcagat agtaaaacag ctacaacaag agattaagga actaagaaac gaaatcaagg
    21301 aactacgcag taatacagga attgagaata caaaagtaca gccggtacag caaacaaatc
    21361 ataaaaaaca gacaagtacc tatcgtgtac cgacggaacg agtatataaa gttctgcggg
    21421 aagcgacaag acagcatctg aaccaagtaa aagaagtatg ggaagacttg ctgatgagtc
    21481 tatctgtcac tcagcgagca atgcttaaag caagcgaacc agttgcagct ggacctacag
    21541 gactagtgat tgcgtttgat tatgagattg tttgtcaaag agcagcaaat gacgaagaat
    21601 tgcagctttc ggtacacaac aacttaagcc gaatgatcaa agattatgcg cctgatcctg
    21661 tttatattac aagagaaagc tggccagaac ttcgaagaaa ttatttgacg caggcacaag
    21721 aagagggaac agaaaactct tttgcttctg aagactcaga aggagaaatc gagttgcttc
    21781 ctcaagaaca agaagtacca gaagaaacac ttgtagtaaa agcagaggaa ctgtttggct
    21841 ccgaagctgt tacagtggta gatgattaat aaaaaggagt agataattat gatgcgtgga
    21901 atgggcaata tgcaaggcat gatgaaacaa gtacaaaaaa tgcaaaaaga aatggcagaa
    21961 gcacaagagc tgctaaataa aacagagttt acaggtaaag ccaccaatga attggtcaaa
    22021 gcggttttta caggcgatcg tcgcatgaaa gatatccaaa tcaatgaaga agtcgttgat
    22081 cctgatgata tcgagatgct tcaggatctt gtcgtaatgg cagtcaatga tgcgatcgca
    22141 caaattgatg tggaaactga gaaaaaatta gggaaatacg caaaaggttt gccaggattt
    22201 tagttttaaa ctgaaggagt aatgaatatg caatatccag aaccaattgc gaaactgatc
    22261 gacagctaca tgaaacttcc aggaatcggt cagaaaacag cgacaagact cgccttttat
    22321 acgatcgata tgaaagatga agtagtaaat gaatttgcta aatctttgtt aagtgtaaaa
    22381 cgcgatttgc atttttgtag tatctgcgga aacatcacag aagaagatcc ctgcgaaata
    22441 tgtagaaatc cttcacgtga tcgaagcgtt atcctagtgg tcgaagagcc gaaagatgta
    22501 atggcaatgg aaaaaatgcg agaatatcac ggactttatc atgttctcca tggtgtgtta
    22561 tcaccgatgg aagggacagg tccagaagac atcaatattt cttctctgtt gcagcggctg
    22621 catgatgcag atgtaaaaga agtgattatc gcaacaaatg caacaacaga gggagaagca
    22681 acagctatgt atctctcacg tctgatcaaa cccgcaggta tcaaagtgac tcgtctagca
    22741 catggtctgt ctgtaggctc tgatatcgag tatgcagatg aagttacttt attgaaagct
    22801 gtcgaaggaa gacgtgagtt ataaatttct aattaagtgt tttttcagat acaatataaa
    22861 agcagcacaa gagatggggg caacaatgtg aacggactat ttattacaat cgaggggcct
    22921 gatggtgcag gaaaaaccag catcttgaat gaactttacc ctcttttgaa agaagtagca
    22981 aaaacagaaa tcattcaaac aagagaacca ggaggcattc cgattgctga agagatccga
    23041 gcagtgatcc ttgatccaaa aaatgatcgg atggatgaac gtacggaagc actgctttat
    23101 gcagcagcaa gaagacaaca tctagtcgaa aaggttctgc ctgctctggc aaaagggaaa
    23161 atcgttttat gcgatagatt tgtcgacagt tctcttgctt atcaaggtgc aggccgacgc
    23221 atcggcgtta ccgagattgc tcggttgaat gagtttgcta cagaaggtac tacgccggat
    23281 tttacccttt atcttgacgt agattcagac accggattaa gaagaatcaa gaaaaacaga
    23341 caaaatcaaa tcgaccgttt agattcggaa ggtttggaat tccaccagcg tgtacgtcat
    23401 gcttacttaa agctggcaga agagaatccg gaaagaatcc acaaagttga tgcaagaaaa
    23461 agctttgaag aagtgctgca aacaagttat catacaatta ttgaacagta tccgcaattt
    23521 tttgaaaact aggaaggtga acgtttatga aaattatttt agcgattatc caagacaaag
    23581 acagcaaccg tttatcaaat gaattgattg atgcaaatat ccgtgccaca aaactatcat
    23641 cgacaggcgg cttccttaag gctggaaaca gtacgtttat cgtgggtatt gaagatgacc
    23701 gtgtagaaga agcattggaa atcatcaaaa aaacgtgtga atcaagaaag caatttgtat
    23761 ctacacctgt tacactggat atttcgatgg atgggggcgt cccttatcca gtagaagtag
    23821 aagtaggcgg tgccacagtc ttcgtcttac ctgttgaagg attccatcaa ttttaggagg
    23881 agctgagcta tgaatcaaga aataaacttg gctcaaatgc aaccgatcgt gtatcagcag
    23941 cttcaacgga gttttgagca tgggcgtatc gctcatgctt atctttttga aggggagaaa
    24001 ggaacaggaa aacatgaagt aggtatatgg cttgcacagc acctgttctg tacccaaatg
    24061 aaagacaatc tgccttgtgg aaaatgcaac aattgtcagc ggatcgaaaa gaaagaacat
    24121 ccagatgttt tggttattga accggaagga caaaccatca aagtcgatca gatcagacgt
    24181 ttgcagacgg aattcagtcg cagcggttac gaatcaagaa aaaaagtttt tttgatcaaa
    24241 gaagctgaaa aaatgaatag cagtgcggca aacagtttgt tgaaattctt ggaagagccc
    24301 cctggagatt ttttagcggt gttagaaaca gatgcagtag gaagaattct ccctactatt
    24361 caatctcgtt gtcaagttct gcattttcaa gaactttcga aagaagcact gatccatcga
    24421 ttgcaagaag agcagattcc attggaaaaa gcaaaacttt tggctttctt aacaaacagt
    24481 ttaggaaaag cagttgaaat ctctcaagat gaatggttta atgatgctaa ggacttgatt
    24541 tatcaatggt tcgtttactt gcaaaagcaa gatactcaag cctttatcta tgtccaaaaa
    24601 aaattggtaa aatcatttaa agaaaaaaca caacagttta caggattatc tgtcttgatg
    24661 ttttattatc aggaagcaca gcgtcaagca gtagcaaacg gcgaatatgg caaagtgaaa
    24721 cagataaacc agataattga acggatattg atcgcagagc agaaactacg cagcaatgtc
    24781 agttttcagg ctgttgcgga acagttcgtt ttgcatacga ttttttagct tgccgcaaag
    24841 gatgatgatc aaggaggatg gaaatggtag aagtagtagg tgtccgatat agagatgcag
    24901 gtcatatcta ttattttgca ccaggagact ctgaatatgt ttatagtgac aaggtattag
    24961 tcgaatctca gcaatcctta catattgcta ctgttgtcct tcctaaaaaa gagattgatc
    25021 ccaatgacct tcctgaagct atccgtccga tcttgcataa agcgtcacaa gctgaattag
    25081 aaaaagacaa aaaaaacaaa aaagatgctt atgatgcatt gaaaatcgca aaagaaaaag
    25141 tgcagttgcg tgagttggaa atgaaaatgg tcaaagccga atacacattt gatcgaaata
    25201 aattgatttt ttctttcaca gcggacgggc gaattgactt tagagaattg gtaaaagatc
    25261 tggccgctgt atttcgtact cgtattgagc ttcgacaaat tggtgtccgc gatgaagcaa
    25321 agataatagg cggaattggt ccatgtgggc gtccattatg ctgttcttct tttttaggcg
    25381 atttcgtgcc tgtatcaatc aaaatggcaa aagatcaaag tttatctttg aatccaacaa
    25441 aaatttccgg tttatgcgga cgcttgatgt gctgtctgca atatgagagc gaagaatacg
    25501 agacagcgaa aaaagaactc cctgactttg gaaaagtaat tgctacacct gatggtaaag
    25561 ggaaagtcgt agggttgaat ctgcttagcc gtatcgttag tattcggctg actggacggg
    25621 aaaatcctgt cgaatatgaa tgggatgaat tgaaagaatt tatccaagta ggtgagatga
    25681 atggataaga gatcattata cgacggattg aatcaattag aatcagagtt gagaaataca
    25741 ttaacagaac ttgttgaaat gaagcatgct ttgcatgaga tcgtagaaaa aaatacaact
    25801 ttggagatgg aaaatcaacg tctgcgggaa cacctgcggg aattgaacca agttgcacaa
    25861 gctccagctg aaaatgtgaa gcaggaactt tctaagtctc gtatgaatct tgaaaaaatt
    25921 tatgaagaag gattccatgt ctgctacgat ttatatggat caagaaggga caatgacgag
    25981 ccttgtgcgt tttgtctaga agtgatctat cgcgaaagcg gtcgatgacc aataacaaga
    26041 ggagactgga gcggagaaat actgctccag tctttttatt aaggagattg tgacagatgt
    26101 ataatcaaaa aagtttcaag ggaaatccgg tatatgggga tttatatctt gtaccgacgc
    26161 caattggaaa tttagaagat atgagctaca gaagtgttcg tatgctgcaa gaatccgatc
    26221 ttatcgcaag tgaggatacg cgtaatacac aaaagttatt gaatcatttt gaaatccata
    26281 caccccaaaa aagtttacat gaacataatt ataaagaacg tgtccctcaa ttgattgctt
    26341 tgttaaaaga aggaaaaacg attgctcaag tcagtgacgc aggaatgcct tccatcagcg
    26401 atcctggaca tgagctagtt ttagcctgca taaaagaagg gatttctgtg atctctatcc
    26461 caggacctac agctgggatg acggctttga ttgcttcagg gctagtgcct caaccatttt
    26521 tattttatgg cttccttcca cgtaagaaaa aagaacagaa agaaacattg aaaaagctaa
    26581 aagaacagac agttacgctg attttttatg agtcacctta tcggatcact gctacattga
    26641 cgaatttctt agaaattttt ggaaatcgcc aagtcgtttt gtgtcgggaa ttgacaaagg
    26701 tccatgaaga ataccttaga ggaagtacgg aagagctact cgcttatatc gaagaacatc
    26761 cagtaaaggg tgaatgttgt ctgcttgtag aagggaattt gttcgaaatg ccagtgacgg
    26821 aagttgatga agagttggga acgttaaagg aacaagtaga agcaaagatc gcttcaggcg
    26881 aaaaaccaaa tgctgctatc aaagcagtag cgctgaaaaa tgggctgaaa aaacaagaag
    26941 tctaccgtca gtaccatgaa ttagactgag atagtataag ttgtctataa tgaaagacta
    27001 atgaggaaat cagctactaa cttttcaaat ctcttgaacg cgaacgaatg ttcttgtata
    27061 atgaataaga ggtgaggatg atggagctgc aatttccttt acataatgat acatcaagaa
    27121 aaatcattca tattgatatg gatgcttttt tcgcttcggt tgaagaacga gatcatcctg
    27181 agtttcgcgg acatccatta gtaattgcca gacaccccag tgacactggt gggcgtggag
    27241 tagtgactac agcaaattat gaagcaagaa aattcggaat tcattcagca atgagtgcac
    27301 aaaaagcgta tgagctttgt ccgcaagcca tctttaagcc tggcgaccat cataaataca
    27361 gcgatatttc caaacaagta cgggaagtat tctatcgtta tacagatatt gtggaaccag
    27421 ttagtatcga tgaagcgtat cttgatgtga ccgaaaataa aatcaattgc aagtcagcca
    27481 tcaaaatcgc ccgaatgatc caagcagata tttgggagag tgtccagcta acatgttctg
    27541 cgggagtaag ttacaataag tttttggcca aattagcatc agactatcaa aaacctagag
    27601 gaatcacggt agttgcccct caagacgctg tgccattttt aaaagctttg ccaattgaaa
    27661 aatttcatgg ggtagggaag aaaactgtac ctagaatgca tgagctaggg atttatacag
    27721 gaaaagacct atatgaatgc acagaaatga tgttgattcg aaattttgga aaaatgggct
    27781 attctcttta tcgtaaagtc agaggaatcc atgattctcc agtaaacgtt acaagagagc
    27841 gaaaatctgt gggaaaagag catacttatg ggcagccgtt gcaaacggaa gaagcagtgc
    27901 tgactcagtt gcgccaacta gctgaaaaag tagaagaagc actgagaaga gtccaaaaac
    27961 atgggaaaac agtagttttg aaggtcaggt acacggacta ttctactgtg accaaaagag
    28021 tgacattgcc agaatatatc tataaaaaag aagcactctt ttatcaagca agccttatat
    28081 gggaggaaat cttgggagta gaaaaaggaa tccgattgtt agggattact ttgacgaatc
    28141 tggacccgat gacttatgaa aacatcgtcc ttccattatg ggaaaatcaa gaaatataaa
    28201 aacagctttg agagttgaaa ccggaaatcc gttttctctc ccaaagctgt ttttatatca
    28261 agtcttgctt tttgatttgt tcataggttt ctgttgcatc cgtacatttt tcccaaatca
    28321 caacttgatt ggattctaaa gatttttgga cgtcaatgat ccgctggttg ctacttccgc
    28381 gaaattgtag ttttaggtca cgtttgctta attcaaagcg tccgtcaaca aggatatcga
    28441 tttgcgaaag gagttctaat ttatcttctg aatcttgtag caattcatca aaggtatagc
    28501 ctgtccatga ccagatatct tttgtcgtac cgaactcttt tcggatacgt cgtacgactt
    28561 gcagacaaac atctgtattc aaaaaaggtt cgccaccaag taaagttaat ccttgcacgt
    28621 aatcgttgcg caagtcagcg atgatttgtt cttctaattc aggtgtgaat ggtttgccat
    28681 atcggaaatt ttgtgcagct ttgttgaagc agccttcgca ggcaaataag cagccactaa
    28741 cgtaaagact gttgcggaca ccttcaccat cgacaaaatt aaacggtttg tagtcagcaa
    28801 tatagttttg gctgtagtct tttgctaacc attcttttgg ttttggattt ctcataaaaa
    28861 aacttctttc atttaaggtt caaagatata gctattgaag ataaaatcta ctcgaccaca
    28921 taaataagaa caaactgacc taaatccatt gttcaagaaa gcttgttctt attttgatag
    28981 agggcgttca aagatacaaa gccatcgaaa gagggtggtg aaaaaagact tgtcatagcc
    29041 tcttattctg aataaacggt gttcaaaagc ttgcatctgc agtaataagc ccaactaaac
    29101 gaaaaatatg aggaactatt tttgtttagc tattcttatt acttgatgca ggacagcttt
    29161 ttcacaacct catttcatgt gtttcacacg tgaggaaatt tctttatggc ggccatgtac
    29221 catcggacga gcttgcggat ttcctaaata gccacaagta cgtttgacta catcacatgt
    29281 ttttggatca tgatttccac attctggaca ttcgaaccct cgttctgtcg gtttgaaatc
    29341 accttcgaaa ccacattgat agcaatgatc gattggcgta ttcgtaccaa gatacccgat
    29401 tttgtcatat gcaaaatccc atacagcttc taaagctttc ggattttgtt ggagcatagg
    29461 gtattcacag tagtggatga atccacctga acaatatttt ggataatcct tctcaaattc
    29521 caatttttca aatggcgttg ggtttttacg cacatcatag tggaaactgt ttgtataata
    29581 ttctttatct gtgatatttt cgatgatgcc gaatttttct gtatccaaac ggcagaaacg
    29641 gtcagttaga ctttcacttg gagttgaata gacactgaaa tgataaccat attcatcccc
    29701 ccatgcatct gcattagctt ttaattcttt gacgatatca agtgtgaaag cttttgcttc
    29761 tgggtttgtt tcccattcgc caccgaagaa agctgaagca acttcataca atccaatgta
    29821 gcctaacgat acagtagctc gacggttttt gaataattca ttgacagaat cggtacgtga
    29881 aagacgtttc ccgaaagcac catacatata taaaattggc gcatttgctg gaatggcttc
    29941 tttacaacgt tctacacgat agagaagcgc atctttcatg atttctaagc ggtcagacag
    30001 taactgccag aatttattct gatctccttt tgattcgatc gcgattcttg gcaaattcaa
    30061 tgtaacaaca cctaaattca ttcgtccgac atttacttct tgaccatttt cgtctttcca
    30121 cccttgcaag aatgaacgac agcccatagg tactttgaaa cttccagtta attcaacgat
    30181 tttatcgtaa ttcagaatat caggatacat tcttttcgtt gcacattcca atgctagttg
    30241 tttgatgtcg taattaggat cttcagggtt taagttcaca ccttttttca aagtgaagat
    30301 cagtttaggg aagatagctg tccgcttttc actccctaat ccattgattc gaatctgtaa
    30361 aattgctttt tgaatttctc tttcaaacca gttttctcct agtccaaatc ctaatgaagt
    30421 gaaaggagtt tgtccatttg aagtaaataa ggtattgatt tcatattcca aactttgcat
    30481 agcatcgaag atatcttttt tggtttttgc ttttgcatat tctttttggc gttctggcga
    30541 atcgatccat tcttccgcgt cttttagatg ttttttatag ttcaattctg caaaaggagc
    30601 aagcaattca tctgttcggt cggcagaaca gccaccatat tgacttgacg ctacattggc
    30661 aataatctgt gagatttgtg ctgtggcggt ctggatagat tttggcgatt cgacttcggc
    30721 attgccgatt ttgaacccat tgttcagcat gcctttgaaa tcaatcaagc agcaattcgt
    30781 catcggtgta taaggatgat aatccaaatc atggtaatgg atatcgcctt tttgatgcgc
    30841 atttgctata tgtggtggca acattttcag tccgattgat tttccaacga tcccggctgt
    30901 cagatctcgc tgtgtattga aaacattact gtctttattt gcgttttcgt tcacgacagt
    30961 ttggtccttg ttgattagct tttcaatcga aaagttgata tctgttgctt tactgcgagc
    31021 aaaatctcgt ttggtacgat aattgatgta ctcttctgct aattcatatt cgtttttttc
    31081 tagtaatata tgttccacga tgttttgaat ctcatagatt ttgacatttt cagcaaaccg
    31141 gcttttgatt tcttggacaa ccaagtctgc aatcatttga attttttcat aagtaagtgg
    31201 tgataatgag ccgtgaattt tcttttctgc tttgatcagt gcttcattga tcttttgttc
    31261 atcgaaatca acatggcggc catcgcgttt gatgactttc atctgggatg tctctggctg
    31321 ctgagtaacg acagtttttt cttcataatt tactttcatt atcttcaact cctgctaaat
    31381 tgttcttgtc tatcataaaa caaaatcggg gaaggagcaa ctaaatatcg gctatatata
    31441 gtattcaatg tgctgtataa ttggatttct atactatatg tagtgtatat tttattgtga
    31501 aaaaaggtga aaacttgtag ctggtggatt tgttttttgc atatttaatt ttgctgaata
    31561 aaataattga ataaaatttt ttattcagtc caagtaaaag tgacaaaaac ataagagcaa
    31621 attattcgta gatatgctac tatgcaaata aatagaaatg aaaaatgaaa gaggaggaga
    31681 agaattggaa aagatgatcg aagtgaaaca tctaagtaaa agctacggca gcaaactttc
    31741 tcccgtcaaa gccttagata atatctcatt cacagtagaa gaaggcgagt ttgttgggat
    31801 tatgggccca agtggtgcag gaaagacaac gctgatgaat atcttgtcca cgatcaattt
    31861 gcctacgatg ggcagtgtct cgatccaagg aaaagaaatc acaaaaatga aaaacagtga
    31921 gctcagtgac tttcgtcgaa aaaaactagg attcattttt caagagttca atttgatcga
    31981 taccctaaat gcaaaagaca atatcctatt gcccctagca gttgaacgga tgactaaaga
    32041 ggaaatggaa aagagagtaa gacatgtagc tcaattgttg aatatagaag aactgctcaa
    32101 acggtatccc gatgaacttt ctgtcggaca gagacaacga attgcagctg ctagagcact
    32161 tgttgttcag ccacaagtga tttttgcaga tgaaccaact ggctctttgg actcgaagtc
    32221 ggctacagaa ttgttgaact acttgaagac catgaatcaa aaagaaaaag caacgatact
    32281 gttagtcacc catgatccat atacagcaag ctactgcgat agaattttat ttattaaaga
    32341 tggtgtgatt ttttctgaag ttgtcagaag agggacaaga agagagttct ttgagaaagt
    32401 aatagacatg caggcgacga ttggcggagg aggaaaaatg aatgctgtat aaactagccg
    32461 ttaaaagttt ttttcggcag tcacgaggct atcttgttta ttttttcagt ttgactttat
    32521 ccgtaatgat ctattattcc ttcagcgcaa tgacctacga tcaatcttta gtcagaagag
    32581 caagtcaaga tacttcgata gatggtggat tgagttttgg tggatttatc attactgttg
    32641 ttttgctttt tttcgtattc agtgccaacc gatttttctt gaatagaagg caaaaggaaa
    32701 taggcatcta tcagcttttt ggtatgaata aactgcagat atcaggtata tatgtgttag
    32761 aaatcatgat aattggattg ttcgcctgta tttctgggat attactcggt attatttttt
    32821 ccaaactctt ttcaatgatt ttggttcgaa tgatggatat ggatcttact agtccatttt
    32881 ttatctccat tccatcagta gtagatactt tatttgcttt tttcatcatc cttttagcag
    32941 tatctgtata ttcaatatgg aaaatatggc gctatccaat gattcgaagt tttggagaaa
    33001 aagaacaagc agatagttca acaatgcgct tcaggacaag gcaccgatta ctcgcagtca
    33061 tcgggttact acttttaacg agcggatatt ttggagctag tcattttagg gaaatcactt
    33121 catggatgat cagttatcat tatcttgata cattagtttt cttttttcct tttttaattt
    33181 ttttcgtttg tgtggtcggt acttatttgt ttttctgtta tacatttcgg ttatttttga
    33241 tcatattgag taaatggaag atttattact atggtatcaa ttttttgata atgggtaaca
    33301 cgcaagttca tttgctcaaa agttggcgta caaattctct gattacagtc attctcggaa
    33361 tttctttaat gacaattggc ggcacggcta gtatctctac tattttatcc taccaggaga
    33421 aagtttcctc cccgatggac tatcagtttg atgttgagac agagaaaaaa atcaagccga
    33481 ttctagcaga ggaagggcag aagataacta aagaaatcac cttgcattat aaagtcattg
    33541 ggagtatcta tagtcaaaat ctcgaagaac ctatgtttca aactgctaat ctgatcacgg
    33601 aaacacaata tcaagccttc agaaaagtta atccagattt gccgaacatt tctttgaaat
    33661 cacctggtca tactgttttg cttgatcaaa tgcaaactct ttttcggaat atttcattat
    33721 atggatctag tattggactg ccagataatc aagaattgaa gattcaacaa atgcttccaa
    33781 gtgtattagg tgacgaaaca atggtatatc taagtcctgt actgattgta gatgataccg
    33841 tttttgaaaa agcaaaaggt gtggattatc aagtagtcaa tgtagatgta tcaggtggaa
    33901 ataatgaaaa aatagatgaa cgactgagca atgacctgtc gataaagtgg ctcaatgctg
    33961 tttattattc ttatgatatc gtaaatggaa gtctacaagg agaaattagc acaaagaaac
    34021 ttccggatga ccaaatgaag gaagcacaat ttagccaaga aagctctcgt ttgaatttct
    34081 cttccagcta ttcgaaattg cgtgcagtta atcggcgaat cggtatcaat atttttgtca
    34141 cactatttgt cgggatgatc gtgattattg ctactggtag tattttgaca gtccggcaat
    34201 tagcagaagc agaggaagaa aaagaaaatt atcacctatt gactaagctg gggattccac
    34261 aaagaaggat cagacggatg atcttcgagc aaaacgcact taccttcttt ccacccatga
    34321 tattagggat cactcacgca gtatttgcaa tcaatgtctt cactcagtat ataaaaactg
    34381 ccgattactg gttggcttat cttgtgagtg gcttattgat ccttatctat cttttgcttt
    34441 atgtcattac gagtcagtta tattgtcgga ttatcgagga atgatatacg gaataagaca
    34501 agataataaa tagaactaaa ttttgaatac catttatttg gaataagagg ttgtgacacg
    34561 atttttgtca caacctcttt attttttata ttttttaaaa gtacgagaaa ttataaagaa
    34621 aaaagcagtg atttgatgtg ctatttttat aaaagctatg tgacaaaact gttagtaaaa
    34681 aaacggtttc tgtaagctag acacatgttt ctttttgtca aaattagtta cactttgtgt
    34741 gaggttatat gaggagggaa tccaatgaac aaatggcgtt ctaatccaaa attgaattat
    34801 tggggaaaat tcatcattcg aacaattttt tatagtgcag tactgctgtt cctgatttat
    34861 ctgtatcact ataaaaatat tcaaggagga acttttatct ataacgaatt ttaggaggaa
    34921 gagtatggaa atcaaaacga ttattgaagc aatcgatgat tggggaataa atgaacctga
    34981 tcgagttgct tatcaggcgg atgagacgca tacttttggt gaattgaaac aagcatcaga
    35041 cgcacttgct tattatttag aaaaaaaggt agaaggcgat ggaccaattg tcgtttttgg
    35101 caatttggag tttgaaatga ttgtctcatt tctaggggtt gtcaaatctg gccatgccta
    35161 tttgccgatt gaagagcata cacccaagga gcgtatccta tcgatctttc gggtggctaa
    35221 accatctatg gtcatcagta tcggggactg gatagaagat attccttcgg ttcctgtcat
    35281 aacaaaaaaa gaatttcaag aaatcaagaa gataccagta ggattttatc ccagaaatag
    35341 cgtaaaaggt acagaaaatt tttatattat ttttacttct ggtactactg gagaaccaaa
    35401 aggcgtacaa atcagtcatg ataatctagt cagctttgtt caatggacga tggaagactt
    35461 tgggatcaag cctggtatgc atttcttagc ccaagcgcca ttttcttttg atttatcggt
    35521 attttctatt tatcctgcat tagtttctgg cggaatgctg aagccgttaa ataaagcagt
    35581 tgttcaagac tttcgtcaat tattcgcgac attgccagcc ttgaagttga atgtgtgggt
    35641 ttctactcca tcatttatgg atatttgctt gatggaacct acattcaatg gagaaaatgt
    35701 gccggaattg gacatgtttt tattttgcgg agaagaattg acgaaaaaaa ctgcagaaag
    35761 tctacttgat cgattcccaa atgcacggat atataatact tacggtccaa cagaagcaac
    35821 tgtagctatt tcaagtattc agattgacca gcatgtacta gatagttatg accgactacc
    35881 gattggctac gtaaaaaaag acacgaaagt ttctattgtc caagaaggta aacctgtttc
    35941 aaaaggagaa acgggtgaaa tcattattgc aggaccaagc gtatcaaaag gttacctgaa
    36001 caatcccgaa aagacagctg ctgcgttctt ttgtcaaaat gacttagcaa gttaccatac
    36061 aggggatgca ggtagactag atgaatatgg gcttttattt tatgaaggac gtatggatca
    36121 gcaggtcaaa ttacatggat accggattga actcggggat atcgaacatt atctgctcca
    36181 agacaaccga atcaaacaag ctgtcgtcgt accaaaatac caaggaacaa aagtacagca
    36241 gctggttgct tttgtcgtat tagaaaacaa aacgaaacag ccggattttc agttgactaa
    36301 atctatcaaa gaacaattac tagaagttgt aatggattat atgattcctc agaagttcca
    36361 ttatgtcgat ctgctgcctc agacagttaa tggaaaaatc gatcgaaaaa aattaacagc
    36421 tgaggtgaat cctgaatgat gttacctcat atgatccctt atgcagagcc gttttatttt
    36481 tttcttttag ccattgcgct tgtaccgatc gttctatctt tattgatatg ggaaaaaaga
    36541 ttaccagttt atcaatcagc agtgacactt ttctttttat ttgtcagctt tggaggtaat
    36601 tattggcaac agggagcggc gctgattggg tatgttttgt ggcagacgat acttgtatgg
    36661 ggctattttg tttatcggca aaggaaaaat cagacaggat ggttttttgc cgccgttatt
    36721 ttagcgataa ttccactgtt tttaacgaaa gtgactcctt tttttgaaca tggaaaagca
    36781 tcgttacttg gttttttagg aatctcttat ttaaccttta aatctgtaca aatgatcatg
    36841 gaaataagag atggcatgat caaaacatat aagccatttc gttatatcca gtttctgctg
    36901 ttctttccaa caatctcttc tggaccaatc gatcgctata ggagatttga aaaagatcag
    36961 ctccatccgc ctgttcgtga taaatatgtt gatcttttgg gaaaaggcgt ccaaaatatt
    37021 tttgtcggtt ttttatataa attcattatc ggttattatt ttggtcaagt actgcttcct
    37081 gtagtgggac gcattgcctt acagcatggt ggtatttcat gggcattagt aggttatatg
    37141 tacgtgtaca gtatgtattt gttttttgat tttgctggct atagcttatt tgcagtcggt
    37201 acaagctaca tgatgggata tcagacacca atcaatttca ataaaccttt tttatcatgg
    37261 aatatcaaag aattctggaa tcgttggcat atgacgctgt ccttttggtt ccgtgattat
    37321 gtatatatgc gattgatgtt cttcatgatg aagaaaaaat tttttaaaag caagatcgta
    37381 atgtcaaata tcggttattt tgctttgttt cttctaatgg gtatatggca tggattgacg
    37441 tggtactaca tcgtatatgg actgtatcat gcttgtctga tctgtctgac agatgcatgg
    37501 atccgattta agaagaagca taaagagcag ttgccttcta acaaatttac gcatggctta
    37561 gccgtatttt tgacatttca agcagtatgt tttagcttcc tgattttttc aggattttta
    37621 gataaacttt tttttagcta acgaatagtg acatattaat ttatataaca aaggagaaaa
    37681 ggaaaatgga agaacaaatt ttatcaatct tagaagaaat aacaggaaca gatgaagtaa
    37741 gaaaaaatcg tgatattgat ctatttgatg aagggttgct tgattcttta gcatctgttc
    37801 aattattagt cgagctagac ggagagctgg atatccaagt ccctgtatct gaattcgagc
    37861 gagaggattg gagcacaccg aataaaatca ttcaacaagc aactgcattg aagggttgag
    37921 tatgaaaaag aaactttttg ctattttcgg cccggttgtt ttagctgttg gcttactgtt
    37981 tgtgtttttt acctcctcct atcaagtaga tatctctaat ccagaaacga ttagacgtgc
    38041 ctcttcttcc atgtcagtga acgtgttgaa aggagatgcg ataaaaaatt atgcattatc
    38101 tgaaaaacaa tatattcctt tttttggctc aagtgaatta agcagaatca gtccatttca
    38161 tccgtctgtt ctggcagaaa aataccagcg aaactatcgt ccatttttgc tgggagcacc
    38221 cgggacacaa tcgttaagcc aatatatgat gatgcgttct gcaggagatg ctatgaaaaa
    38281 caagaaagtc gtctttatta tttctcctca gtggttcgtt aaaaatggtg taaaaactga
    38341 ttactttaat acgtattatt ctgaacttca aacatacgac tggttgtttt caatgaagaa
    38401 agtaacgcct gctgatcgct atttagctag aagattatta actttctcaa aagtaaaaga
    38461 gaatgatacg ttgacggcga ttctgcaaac gatcaaaaaa gggaagctac ctttacctga
    38521 atctttgaat cagctgcgca gccaatggaa catgctgaag agagaggatg aagtattcag
    38581 caatattggg ttgaaagatc gacagcaaaa aatcgatcat gagtcaaaac gattaccaaa
    38641 acaataccaa gaaacagaat tatccatttt agcaaatcaa attggagaac gagaaacgac
    38701 gaataatcca ttcgggttga aaaacgattt ttatacgcat cgtatccgag cccacgagcc
    38761 agagctcaaa cagtcacaaa aaaattggga ttatcgtttt tcgccagaat tttctgattt
    38821 tcagctggtc ttggatcaat tagcaaaaaa ccataacgaa gtattgttca tcatcccacc
    38881 ggttaacgag aaatggagcg attataccgg actatctcaa gaaatgttac aaggatttgc
    38941 caaaaagatc aaatttcaat taaatagcca aggattcaat cgaatagctg attttgtcaa
    39001 tcaagcgggt accaactatt ttatggaaga cacgatccat ctaggctgga aaggctggtt
    39061 ggctgcagat caacagatca gaccgttttt agaagaaaat catattactg ctagtaagta
    39121 tcatcttgac gatgcttttt ttagcaaatc ttggcaacat caaataccag ataaactaca
    39181 attaaaataa agaaaacagg cgagtgttgc tcgcttgttt tctttatttt tgaatattct
    39241 gaataaaaga taaaaatacc aagtttgcct gaacaaaaat cataagcaat ggtataatca
    39301 caatatgaat atagaaatgg gggaaaacat ttggatacaa aagaagaaca gctacttatt
    39361 gatttaactt ctgcaaaagg agtacctgga aatgaagaag aggtaagaga agtattcaga
    39421 gaatatgcca aaccattcgc tgatgatatt ttttatgacg gtttaggcag tgtgattgcc
    39481 aaacatggtg ctggcggagg ccccaaggtc tttatttctg gacatatgga cgaagttggt
    39541 tttatggtaa caaaaataac cgaaaaagga ttcttggaat tccaaactct tggaggttgg
    39601 tgggggcaag tcatgcttgc tcagcaagtt gaaatcaaaa cacgtgaagg gaaaatcgtc
    39661 cacggtgtga ttggttccaa accaccacat gttttaacac ctcaagtaag aaataaacct
    39721 tatgaaataa aggatatgtt cattgatatt ggcgcatcaa gccaagaaga agccaaagag
    39781 tggggcatac gtcctggaga tatggtcact ccatatattg aatacaaacg aatgaatggc
    39841 agtaaatatt tactggcaaa agcatgggat aatcgtatcg ggacagctgt ttctctgcga
    39901 gtattagaga atctatctaa agaagcacac ccaaatgttt tattcgcagg aagcgatgtg
    39961 caagaagaag taggcttgcg aggtgctcga acaagtacac accttgtaaa tcccgatatt
    40021 gcttttgctt tagatactgg tacagcagga gacactccag gaatgacacc aaaagaagca
    40081 gattcgattt taggaaaagg cccacagatt ttgatttttg atgcatctat gatcccgcat
    40141 aaaaaattat tgaattttgt tattgatgta gcagaggaaa tggatattcc attccaatat
    40201 acagtgattt ctggcggagg aactgatgca ggacaaatgc atttgacaag agatggtgtt
    40261 ccgtctgtag ccattaccgt tcctgttcgt tatctgcatt cccatacatc agtgattcat
    40321 gaagatgatt atttgaatac agtgaaacta gtcacagaat tagtgaaacg gcttgatagt
    40381 gaaacagttg aaaaaattcg gagttatgaa taatgaataa tagaatacct atttctgaat
    40441 atcggaaaaa agcacgagtt tctttggaaa atcaatgggg aatcaatact tggcttgttt
    40501 tcttatctat aatatttacg agcgtcatcc agaacttttt tgacggtttc agtccttttc
    40561 cggaagaaag catgcagcag cacttattga gttttctagt cgataattta cttttattcg
    40621 tattcaacta tgcattgttt tacattgcgc tagtagttgt acggggtggc agaccaaaaa
    40681 gtaacctttt attttcagtt ttccaaagaa agtattttgg ttcgatactt ggcatcaatt
    40741 tgatcaattc agtcatcaac tggctactca acagtttaat ctttctgccc atgtttttaa
    40801 tcagcggagt gagtacttat atgcagctgc ttttcagttc aaatgcggta cctacgggtg
    40861 tcatgccaga agattttctt gatatcagct ttgttttatc gatgataggg atgatttttg
    40921 tttcagcact catcatgagt attgttggcg gtttattcca atttgctgca tggacaaagt
    40981 tcgactatcc tgatttgtcg gttattcaat gtttgaaata tggctggttt ttattgaaag
    41041 atagaattgg tacgtatatt ttgttgcagc tgtcttttat cggctggtat ttgctaggag
    41101 caatcgcttt gttcatcggt cttttgtggg tcattgttta tgtgaatgtg tcagttgcag
    41161 aattttatga acaagcacgg attgaaaaag gaggtccaga cgcctatttt acttagcatg
    41221 taagcagttt attcatcaaa aaaataactt ttgtggtagg ataaatcttt gagggggaat
    41281 gtacgatgaa attaactgtt ttaggatgct taggagcgta tccttataaa aatcaaggga
    41341 caacaggtta tttgcttcaa tctgacgggt tcaatttgtt gatcgatgca ggtagtgcta
    41401 cgctgatcaa attacaagaa caccttgatc cacttgatct agatgctgtg atccttagcc
    41461 attatcatca tgatcatatt gctgaccttg gtgtattaca gtattactgg caacttcatc
    41521 ctaagagaaa tccggagaca ttgctttcaa tttatggaca cacaaaagat tccattcact
    41581 ttgaagaatt gacgttggaa aatgtctcaa aaggacatcc ttattttgaa gctgaagaat
    41641 taaaaattgg tccttttctg attactttta tggaaacaat ccatccagta gtatgttacg
    41701 ccatgcgtat cgtagaagaa acaacgggga aagtattcgt atttacaggt gattcaggtt
    41761 atttggaaag tttcgctgat tttgcgaaag atgctgattt gtttctagca gatacctatc
    41821 tttttgaagg aaatgaacat catcatgccc atttcacttc aaaagaagct ggagaacttg
    41881 cgaaatcagc taacgtaaag aaacttgtac ttacacacct acctcagttt ggtgatttag
    41941 aacaattgaa aaatgaagcg caaaaggcag caggcaaagg gattgatata gaacttgctg
    42001 cagttgacaa agtgtttaac atttaggagg aagaacatga tttttgtacc aaatgaaaac
    42061 cacgacccaa gaatcaattt agcaattgaa caatatttgc tgcaagaaat gcctttagat
    42121 gaacctattt tgctctttta tatcaatgaa ccttcaatca tcatcggcag aaaccaaaat
    42181 acgcttgaag aaatcaatcg agattatgtg gaagaaaatg gcattcatgt tgtccgtcgc
    42241 ttaagtggag gcggagctgt ctaccatgat tttggaaacc tgaactttag ttttatcatg
    42301 cctgatgatg gggattcatt ccgtgacttt gcgaaagtaa cacagccaat catccaagca
    42361 cttcatgaat tgggtgttgc tggggcggaa ttgaaaggcc gaaatgatct agtcattgat
    42421 ggcatgaaat tttctggcaa cgcgatgtat gctaccaacg gtcggatgtt tgctcatgga
    42481 acaattatgt tcgactctga tatcaatgaa gtagtcaatg cattaaaagt aaaaaaagac
    42541 aaaatcgaat caaaaggaat caaatcgatc cgttctcgtg taacgaatat caaaccattt
    42601 cttccagaag aaaagcaaaa aatgacaaca gaagaatttc gtcaagaaat cttgttgaaa
    42661 attttcggcg tagagtcagt agaagaagta aaaacgtacg aattgactga tgaagattgg
    42721 aaaaaaatca atcgaatctc tgaggaatat tatcgaaatt gggattggaa ttacgggaag
    42781 tctccagatt tcaatttctc tcgccaaaaa cgtttttcta tcggttcgat tgaagtccat
    42841 ttgaatgtct cagaaggaat gatcaaagaa gcaaaaatct ttggcgattt cttcggacta
    42901 ggagatatct ctgacgtgga aaaaaaattg gttggacaga aatatgataa agcatctcta
    42961 tcaaaaatag tcagccaaat tgatgtgaag aaatattttg gtgcgataga accagaagaa
    43021 ttgcttacct tactttattg aaaataaaaa atagcggaat ccacatatat ggattccgct
    43081 attttttata caggattcgg gtaatttcga gagagttgaa cagtgatccg atcaatgaaa
    43141 gtatcttttt cctgcgttag tgttcctgtg taacgatccg ctacgtcttt catcatcatt
    43201 aagtcaaaac gttcctgatc atctaattct tctgtgatgc ctcgactaaa taggtttgta
    43261 tcgtaatgtg cactatgttc gcaacaaatg acgaaatgtt cctcttgttc gtgtatcgac
    43321 aaataaattt ttcgatacag tggattttcg atggcatgag tttctctaaa ggaatgctct
    43381 aaagcgtgga tcaaaagttg agccagatcg tcatcgttga taggaagttc ttcgggaaga
    43441 tctgcttgga aggttatctg aatattccgt ttggcagcta acttctggta acgcgctaag
    43501 ataagatttg tcacctggtg gttgcaaaaa gaacacagca tttcgaaatt ttttgcttct
    43561 tctaatatct tttccacata gtttttagct tttgtttggt ccgtatgcat taaatcttgc
    43621 agattctcca tctcttggac aaattccagg cgaagtgtat ttacttcttg gatatgctgt
    43681 cgaagctgct cataatgttg ctccaacaaa tcatttttga tttttaagaa atctacttgt
    43741 ctccgatctt tgtcggtatt taagatgtga tcgattagat tgtagctgat aataacgatt
    43801 agaatgataa tatataaaat cgtagaccaa ttgatcgttg tttgatagat acctaatgcc
    43861 gtttggatgt aaatcaagca atggataatg gctaccaaga cgatccaagg tgtacaagct
    43921 acataaaaac ggttattctt atatgcttcg ccaatgcatg caagtgaagt gactaaagtg
    43981 cttataacac tagcaatatt agcaatcggc attaattcag gaagttctgc aggagtaaaa
    44041 gttgcataaa gcagaacgcc gataaaaatc aaaagttgga acgtacaaaa aattccgtac
    44101 cattttttat agtaaaacat tcggctccaa tagtagcaga tgatgaaagc tgacgttaag
    44161 ataataaata aatgagataa aaaagaatga acgaatggtt caaaaagaat accacttaaa
    44221 atatcttctg atacagcttc aaatcctaat gccaaagcaa agcaacttaa gagaataagt
    44281 gagtattcaa gacgtttttg tttatacatc aagtagatcg tatagaaaaa ggtccctata
    44341 gcgataaaaa cagcgattat catcgtcaat acttgcggca ctgattgtga ataaataaaa
    44401 ctaatcaatg gtccagttgt tcctagataa actttcggtg gcagtccagc atagttctga
    44461 taaggagatg agactgtaag ggtcaatttt tttccgatat aatttgctgg taaatctatc
    44521 acagccaatg agagtccggg attgctttct tcctgataat ctttccgttg gtataaaatc
    44581 ttttcgccta gatatacagt aatccattga tggtttcctt tgattagtaa atttgcttcg
    44641 tccaacggtt tttcaagtgt cgtttccata atgaatgttt cgtctttatc cacggtagga
    44701 atcgtacgag tgtacttgct gtcaaactta aaatcaggat catcttttgt atagaaaacc
    44761 cacgaatctt ttatttcttt catttgattg ctgtccgcag gagaaaaaat aaaataaaag
    44821 aaataagcaa ttcctgttaa aaataacaat gataatataa tgattatgct ccactttata
    44881 cgtaaataaa aagattcttt tttattatat atgttattaa aaaaagacat aaaggtattc
    44941 ctttctaaaa cttgtaatgt tagggtaaac gttttttaaa ctaacgtcaa ttatttataa
    45001 taaaaaatga gataaagatg aggaaataga attagaaaca tataattatt aaagggaaac
    45061 atttttacag ctataatttg aaaaaaattt atcgttatta tatgattaag aaggattgaa
    45121 taaagaaaga agttgaaaac gatacctgat tacaaaaaaa taacttttat aagttctata
    45181 acgttgatta tatttttaat tcttattctt ctcgtcgtct tggttccccg aatttttggt
    45241 ttgactcctt atattattga ggacaaagaa atgagtccat attatgcaca aggaaatctg
    45301 atatatgtac gaccgaaaaa tacaaatgag attttagtcg gagatattat tacatattat
    45361 gaaaattcag gaaaaaaaat ctcgacgcgt cgcgtaatag ccgttgaaaa caaccacgaa
    45421 gatttttata caaaagctga tacaaagact tatattgagc ctggagtagt aaaaaagaga
    45481 aatattatcg gtagtcccat ctttcagatt ccatatattg gactagtcct ttcaaaaacg
    45541 gcatttgcat ggattcaggg gttattcttt acgattgctt tttgcctaac aggaatcaca
    45601 gcatggaata cctttgtaga gttgaaaaag aagcggagac gaacacagaa atttttgtaa
    45661 gaatgttaaa aacataaatg tattccagag atccaacgac tcttctgaac atgaaacacg
    45721 agaaaacact catgcagctt gtagatttag tcagttgttc gtataatgtg tgaagaggag
    45781 gagtagtatg cgcaatgaaa tgatgcatcg tcctgtagtc aaagaagaac tattggattt
    45841 tatgcgtacc cagcaaaaaa aattaccggg tgagctaggc aaactggaag aagaagctca
    45901 tgtagcagaa gtaccagtta ttccccatga aacagttgta tttttgaaat ttttacttgg
    45961 acagcttcag cctgaacgaa tcttggagat cggagcagct atcggttttt catcaagtgt
    46021 catggccacg acaatcggag aaaacgctca tgttacgaca attgatcgtt tcgatgtcat
    46081 gatcgagaaa gctaaaaaaa actatgaacg tctaggactg acagataaag tgactttgct
    46141 tgaaggtcaa gcagcagata tcttgccgga gttgtctggt ccgtatgact ttatttttat
    46201 ggatagtgca aaatcaaaat atattgaatt tttacctgaa tgcttacgtt tgttaagaaa
    46261 aggtggcgtt ttgatggtag atgacatctt ccaaggagga acgatcttgc tcccagatga
    46321 agagattccc cgtggcaaac gagctatcca tcgtaaatta aatgaatttc ttcgtgttgt
    46381 gatggatcat cccgatttga catcgacaat cttgccatta ggtgatggtg tgatcttaat
    46441 gacaaaggaa tcagaaacaa tcgagttgtg atacatgatt atggcagcct gtagataatc
    46501 gattgaatcg agggctcaat tcgaacttga tgtaaaagtt tctatatttg taagtcaatt
    46561 aaaggataca ggaaatctaa ataaacagga gtagcatgaa gtcaatgtag ctcctgtttt
    46621 caattgataa ccttagaaca gctgaaggag aatgtctcgt tttaaaagat tgatttagta
    46681 gttgggccaa aataattcat tatttgctaa ttaaataact atttcgtatt gacagaagca
    46741 atttaattat ctataattat tgatgttccg ctgattcttg tcatagtagc tcagctggat
    46801 agagcatccg ccttctaagc ggacggtcgg gggttcgaat ccctcctgtg acgctaaaaa
    46861 accgttagaa actgaggttt ctaacggttt ttctttgttt tttgtgccaa tattgtttgt
    46921 tttcaaaggc aaataaaata aaaaaacatc cttatcgagt acaattataa ggagcaaaaa
    46981 aataaaactc atcagaaaag aggaagaaga tatgacgata ctatctagaa ttttagtgac
    47041 tctagttgca attgaatttt tttatatcat gtatatcgaa acggtgagaa ctgattctga
    47101 cacgacaagt agggttttta aaatgagtaa agaagagtta agcagaaaat ctgttcaaac
    47161 attgtttaag aaccaaggag tgtacaatgg actattagga gtgggactac tttatggagc
    47221 ttatctttct tccgcatcta aagaaatcac aagtatgcta ttaatatcta ttttttttgt
    47281 tgcattatat ggcagtttga ctagcgatcg ttggatttta ctcaaacaag gtgggctagc
    47341 tctgttggca ttgctttcta ttttcttata aatatagaaa aaataagaat ttatctaaca
    47401 ggaaactttg tgaaaaatat tactttatct catgaaatat gatattctaa tgaatggtat
    47461 tttagaaaat ttcatgaaaa aggagttaga taggtgttca aaaattatgt ttcctcacta
    47521 aaaaaagaat tttcaggtta tgatctttca agatttcaga aagatctttt ggctgggatc
    47581 acagtagctg ctgtagcatt gcctttagcc ttggcttttg gggtatcaag cggagctgat
    47641 gcggccgcag gtttgattac ggctatcatt gccggtatcg ttattggcgg tttatcaggc
    47701 ggtttttatc aaatatcagg tccgacaggt gcgatggcag ctatcttgat gtctattgcg
    47761 gcaacaaagg gaatgcaagg tgtattgctt gctacttttt tagcgggtct atttttactt
    47821 gcagcaggac ttttccgatt aggaacactg acttctttta tcccagcacc cgtaattacg
    47881 gggtttactt caggtattgc tatcattatt gcattaggtc agatcgataa tttatttggt
    47941 gttcactcgg aaggtacaaa cgttattgaa aaactaagta gttatcaaac gataggattt
    48001 ccgataaaca cagcctcttt gatcatggga gggctagtca ttttagggat gtttatctat
    48061 ccaaaaaaat gggcgaaacg aatgcctagt tcgctgctgg ctatcatttt ggcaacagca
    48121 gttatgctat tgttccattt accagtagca actgtgggta agattccaca aacattgatc
    48181 agtagtaatc gtttgaatat gggagatttt agcttttctg ccttgcaaca agtggcagtt
    48241 ccagctatta gcattgcttt attaggaatg attgaaagct tgctatgtgg tgcttcggct
    48301 ggccgaatgg caaataagcc cttagatagc aatcaagaat taatggcgca aggaattgga
    48361 aatctgttgc ttcctttctt tggcgggatt cctgctactg cggccatcgc ccgtacaagc
    48421 gtggccatca aatctggtgc acaaactaga ttagctggta tgatacatgc agttgtctta
    48481 ctgctctcca tgcttgtttt tgcgccagtg atgtcacaga ttccaatgcc agcacttgca
    48541 ggtgttttga ttgtgacggc ttggcgtatg aatgaatggg aaacgatcaa ggagctattt
    48601 actaataaat attggtcagc agttctattg tttatcctta cgatgatttg tacagttatc
    48661 tttgatttaa gtattgctat cgtgatcggg gtgatcggcg gctgtgtatt ttttgttgtc
    48721 aaaagcgctg ctatcacgat ttcattagaa acgatcgatt ggcaaagaat ggggctgcca
    48781 gaaacggaaa agctgaataa ctggacagta gtgtatatta gtggtccact gttttttatg
    48841 tcttcagaaa aactcaaaaa taaattggaa gaactaaatc atcacgatgg tgtcattttc
    48901 tccatgcgag gcgtaccaag tattgatttg acggcacgtg cagtttttga tgaatttcaa
    48961 gaaaaagcag agcaaagagg acaaacgatt atctatactt ccttgcagcc agaagtagaa
    49021 aaacaacttt ctcacttgtg ggaacataca ttcacgcatc aacatcaaac agttgctcat
    49081 gcgttgacag ctttacatgc gaaatatact gcaattagcc attaaaacaa tgaaaaagaa
    49141 cagacaagac tgtaaactga agattttatg gtcttgtctg ttctttttaa tattgctgta
    49201 aaagtgaagc tagtacttgc cagtcttgat ggataacagg tacaagggag cgattgtaga
    49261 aaatagctgc tggatgaaaa agtggaagaa ttcgatagtt tttttctgac cattcgtagg
    49321 catccttttg ttctgttaat tgtaagacag gccctgtata gagttgacca tgatttttgg
    49381 taaccgtata ttctttgcca agtaaacgtt gaagaccaat gtttccaagt gtcgcaatta
    49441 attttggctg gaccttcatc agttcgtaat ccaatattgg tgcatgcgca aatacttcgg
    49501 aacgagtagg tgtccgattt ggataaacag tttctgactg ttgtgtccgt ttattgatcc
    49561 gatgagtcac gcgatacggg cggctcctta cagcactggt gatatacacc tcttctcgtg
    49621 ttaagccagt tgaagaaagt gcctgcatca attcttttcc agcttgaccg ctaaaaggaa
    49681 catgcgtatc aatctctgtt ttccctgggg cttctcccac gagcatcagt ttaggatgaa
    49741 gaggtccttg cccagcgata aatccttcta caggacggcc gttcattctt aaagaagctt
    49801 cttgtatcag ttcttttggg tattccattt atgctcctcc tttttctttt attataagaa
    49861 taaaagaaac acaatgcgac tattttattt ggtagaactg tgaggataga aaagcagaag
    49921 tattgcttga atttttgttt tactttttga ttttaaattt agttgactaa cggttgctgt
    49981 tctggtaagc tagtactgtt gtaattgtgg actccacagc tacaaccgct cagaacaagt
    50041 aataagcaca gcatatgctg tcacttcgga tggcgagtct aagtatatca gaaggaggtg
    50101 ctttatagca tgtacgcaat tattaaaact ggtggtaaac aagtaaaagt tgaagtggga
    50161 caagcaatct atgttgaaaa acttgacgtt gaagcaggag aaaaagttgt ttttgacgaa
    50221 gttatcttag taggcggaga atctacaaaa gtaggcgctc caactgttgc aggtgcaact
    50281 gttgaaggta ctgttgaaaa acacggcaaa caaaagaaag tcgttacttt caaatacaaa
    50341 cctaaaaaac attcacaccg taaacaaggt catcgtcaac catatacaaa agtggttatc
    50401 gacgcgatca acgcttaata gcgtttgaga aagaaggcct atatatgatc aaaggaacat
    50461 ttaagcgaaa tgacgcaggt cagatcgttt cattcacttt gaccgggcat gctgatgctg
    50521 gtccttatgg aagtgatatc gtttgtgcgg gtgtttctgc gttagcgatc agcactgtca
    50581 acgggattgc ctcattagcc ggttttgagc cgattgttga aatgaatgaa gaagaaggcg
    50641 gttatcttta taccgaagtc acttcaggaa tgacacaaga acaaaacaat attgctgaga
    50701 ttctattaga aaatctttta ttaggattac aatcgataga agctgaaaac tcagaatata
    50761 tccaaattaa aacaattaat gataaatagg aggtgcagac catgttgtta tctatgaatc
    50821 tacaattatt tgcccacaaa aaaggtggcg gttctacatc taacggccgt gactcagaat
    50881 caaaacgtct aggtgctaaa cgtgctgatg gacaaacagt tacaggtgga tcaattcttt
    50941 accgtcaacg cggtacaaaa atctatccag gtgtaaacgt gggtatcggt ggagacgaca
    51001 ctttatttgc aaaagttgat ggcgtagtac gtttcgaacg taaaggccgt aacaaaaaac
    51061 aagtgtctgt ttatccagta gctcaagaag cttaataaat aaactgctct atctcttgtg
    51121 tagcaaggga tggagctttt ttgtaaatta tgggattttt tttgaccata cttttgacca
    51181 tactttctta gaagttaata taatttgtta gtttttgtgt tgtttcttct tttttgctgt
    51241 tagtaatgtg tgtatatgtg tccatagtag tttttatatt tgcgtggccc attctttctt
    51301 ggacttcttt gtgatctgcg cctgcctcat atagcattga tgcatgtgta tgtctaaaac
    51361 catgcagacc gatataaggt aagccggcac gctcacgata tatattgtat ctttctgcca
    51421 ctgactgatt aattgtgaaa ttattttcgt cattggtaaa caaataatta gctttagtaa
    51481 atcctaattg aaataagtac tttctttgtt cgagcttcca aaattttagt tgctttatag
    51541 ttttttcatc taaataaatt attcgatttg attttttggt tttaggagtt tcagatatat
    51601 aatatttatc tgaacgagct acagtttttt taatggccat ttcatttgtt ttaaaattaa
    51661 tattgtccca agtgagtgct aatatttcgc cgattctaca tccgctgaat gctaatagtc
    51721 taaagagcgt atagtctctg tttttaaaat atggattctg ttcttgagat acttcattta
    51781 gaaataattc caactgttct tttgtatata attttaattt cttttctgtt ttaatttgtg
    51841 gctttggaat aagtaaattt aatgttggat tatcagatgt taaaccaata tttatagcat
    51901 acttaaaaac tttattcata tagtttatga aaagagggta ctgctttgaa gttccttttt
    51961 cactccaatc atttactacc ttttgacaat atgccgtatt aattttagaa agcttaatat
    52021 ttccaaattt gggatatata tgtttattaa agattatttt agtccttgaa tatgaacttt
    52081 cttttacagt ttttttgtag ctttctagcc ataattctgc tgcttctttg aaagtagtat
    52141 ttgtacttgt gggcattcct gttttttgta attctagttc taacctagaa agtgctgttt
    52201 ttgcttcttt ttgtgttcta aatcctcgtt tagtagtata ttttttcttt ccagttagcg
    52261 gatcaatacc gagataagtt ttaaagtacc atgctttttc gccatttttc tttttatatt
    52321 gttttatcat tgccatcaat attaccccta ttcaaattct aattctgcca tgctatcatt
    52381 gaaaaattcg atcagtcctt gttcctctat aaattcaagc catatttcct tcccgttaat
    52441 taatggaact cctttttctt tacgaattgt ttgatacaag ttagtcacga cttgtttcca
    52501 catttctaat acagctttat ctattttctt atcatcccag cgtttttttt ggggtctatt
    52561 tttgtttttt tcaatttgat aattagtagc tttgatgata aatgtttcgt atccggttgt
    52621 gcttttttct aaccattctt tgaattctgt atatatcatt tttgttcacc tttctatttt
    52681 tgaacgtatg ttcttttttg cttaaaaaat tttagagagc tgcataacaa tagatgcgag
    52741 cttttaataa ttctttcaca agtggttcga agcgaacgct taaattgtta tcttctataa
    52801 atttcatgta attgatattg tgtggttcta attcagactt tgcaatatat ctatctaata
    52861 atttttcaat catgaagcga tcagcctcat attccatttt tgaatggaga gagaatgcta
    52921 agttatataa aaaataatta tcatgatgtt tagaagcgtg tcctaattca tgtaataagg
    52981 ttctttgtct tctatactta gataaattag cttttattac tatggtattc atacaagcaa
    53041 cataatggcc atcggcatca aggttttcac gctcttctac cttaacgccg agttcattaa
    53101 ttatcatttc aatttgactg tccaaatgac tcacctactt atttagttat cttttttctc
    53161 taaatatgct tcaatcatag ctgatagtat ttccctatca ttatcggtga gcggttttcc
    53221 gtcgctactc ataacagatg ctaaagcttc ttccacggtt agttttcttt cctctggtgc
    53281 aactcccgcg ttaggatcat ctgtgcgtcc tagcaaataa tctgttgata catggaagta
    53341 gtcagcaact ttttgcaaag tttctatttt aggactttgt gtcttccatt tataaataga
    53401 gttttttcca aatcctattc tattttctaa ttcagaaata gaaatacctc tttttttaca
    53461 gagctcttta accctttcga aaagcatgtc aaatcaacct tcctagagcg tacgataata
    53521 atttatacaa aaagatagaa aggtagttga caaatctatc caattgtctt atatttaact
    53581 cgtaagctaa tttaataagc taacaagcaa caagaaatac acctaataaa ataaacgaat
    53641 tcgaggtcgg caaactaaga atgttaattt ttagggtttt tctaggctta tttaactgta
    53701 tataaatata agacagttgg atagaaatgt caataaaaat tagctaattt tattagctta
    53761 catatttaaa gaaaaggagg aaacatcatg aaacaaaata aaaaaactcc ttccgcaaaa
    53821 ggagctttaa taactttaaa ttttaaagac caaaagttta gtgctgttgt tgatgaaatt
    53881 catccacaag agcatcaaaa aaattctttt gcaactgacg agaaaaagac tcagaaacgc
    53941 tctgagaaag ttcttcgaat aattcaattt ctgttggaaa agattcgtca ttttggaagt
    54001 ctattttgaa ttctttatta acagtcttga atacggtttg tttgaataag gcgtcgacat
    54061 ccatattaaa ttcttccata ctattttcac ctcgctttct attcaaaatt atatcaaaga
    54121 aaggaatgag caaaaatgaa cacaccgcaa atttttaact ttgaacaaca tgaagtaaga
    54181 acagtaacaa tacatgatga accatttttt gttggaaaag atgtggctaa agttctaggg
    54241 taccaaaatg gtagtagaga tattaacaga cacgtcgatg tagaagatcg gcaaaactac
    54301 caaaacggta cttttgaatc gcctagaggg ttaactatta ttaacgaatc aggtttgtac
    54361 tccttaattt taggaagcaa acaaccaaat gctaagaaat ttaaacgttg ggtgactagc
    54421 gaagtgttgc cagcaattag aaaacatgga ggttatctaa ctccagaaaa agtagaagaa
    54481 gctttgctta atccagatac aatcatccaa ttagcaacta agttgaaaga agaacgtact
    54541 ggaagactaa tcgcagaaca aaaaattgca gaatacgaac ccaaaatttc gtatttggat
    54601 agtatcttat cttctacaga ttcagtaact attagtcaaa tcgcggctga ttatgggatg
    54661 tctccacaac agatgaacaa actacttcat aagctaggta ttcagaaaaa agtaggcaac
    54721 caatggttat tatgcaaaaa acacatgaga cagggttaca caaaatctca tacaactgag
    54781 attccgaaat ctgatggcgg aacaaaagtt gtgatgaata caaaatggac tcaaaaaggg
    54841 cgtctgttca tttatgagtc gctgaaaaaa gaaggatata ttccagaaat cgatttatta
    54901 gaggaggaat gacgatgtca caagaattta ttttgaaagt cagaattcaa ttagcaaaat
    54961 acggaaagtc tcagaactgg ttagctgata ctatcggaat ttctagacca tatatgtcgg
    55021 acattatgaa tgggcgtaga aaaccagata aacaaatcaa gccaattgag gcagcactag
    55081 cagagttaga gaaggagaaa taacatgcaa ataacaattc cagataattt agtagtttcc
    55141 gaattaacta cacagattac gaatgctgtt cttaattcat tggacgaacg attacacctt
    55201 atgaacaaat cagtagagct tcctccatat ccaaacaaat cagaggtaaa aaaagtttta
    55261 ggcattggtg atgacaaatt aacacattgg ataagcctag gcttaaaaac acagcagtgg
    55321 agcaagttag acatcagaat tgaacgatcg gaactccaaa gatttttgaa agaaaacttt
    55381 gagttctaaa ggcaaaggag aatgatttta tgtcctacac attgcaacaa gaacatcaaa
    55441 ttctaggtct gattaaacag cgtagaaaac aattacaaga tgatcgtgca gcgcttagaa
    55501 aatccgatga gctatcagat agacaagctg aactaattgc ttctgaactt gaggatttga
    55561 gaatgctaga aataaaaaat agggagatta gattatgaag aagacagaca cactttttat
    55621 aggattcatt ttggggttat tagtgattgt agcgcaccaa agtattatcg gaggaagctt
    55681 gttcgcagca ttgatggttt taatcaatct gcttgactca aaagaaagga gcaactatgg
    55741 cacgagaaga agcgctaaaa atcggtaaag tgattgctga taattggtgg gcaaatagcc
    55801 gttctattat tttaagcaag caacatatcg aaaagaaaaa agcatggcaa caaataaaaa
    55861 agtgactccg ccgaccaaag caatgagtca ctcaaaaaat cataactaag gagattttaa
    55921 catatggaaa atgaactttc cactctagat caatatttgg ccgatcctga ttggggcaaa
    55981 tcgaatttac aactggttgc taacaagtac gaaaaatcaa ttgatgaagc aattgttgca
    56041 ttgactgatg cagcttccat aaccgctgat gacagtaaat ggaccaagag agacttgggc
    56101 attctaaaac gaggcgttaa ttggcttgaa gatcagtaca gagaagaaac aaaagagaag
    56161 tgatatgagt gtttaaacca ctaatagatt catactcggc ggtactaaag aaatttaaag
    56221 gtaacgacat tggtgcaaca atcaacgaag aagtaaatat cgaacggctg aaaacgatgt
    56281 atgacggata tgatggcgat cgagtcattg aaattcgctt tattgatcca cgacggttca
    56341 cagtacagca aagaaacttc atctatgcgc tcataggcga tattttcatc gatacaggca
    56401 tgccaacgga cttctggaag gaattcttct acttccgttt tgaaggtgtc acagggcgcg
    56461 aaataagcct caaagacgaa tcgaatacaa ccgtgagtga tgccaatatc ttagcgaata
    56521 tcatcctaga tttcatcttt gaacatcata ttcctttcaa agaaggatat gagattttac
    56581 cagcgaatca agagtattac ttctacaaat gcattacaaa aagagtctgc tgcatctgtg
    56641 gcaaaacagg agctgatatc gatcactttg acaaagcgct gggaagacga aagcgcaaag
    56701 aagttgatca ttcagagtac acatttgcag cactctgcag aatccatcac acagagaaac
    56761 acaaaatagg tgtgatcaat ttcaaaaata aatatcaaat caaagggatc aagttaaacc
    56821 aggaaacaat taaaaagtta aggataggag gataaatttg gctgagataa gttggatcaa
    56881 acttaaaact actatgtttg acgatgaaaa aatacgatta atccaagctg ttcctgagtc
    56941 ggatgccatc atcgttatat ggattcgatt actagtttta gcaggaaaga ctaacgacga
    57001 tggtctgata tatatccaga ggaacatgcc ttataccgaa gaaatgcttg ctacattgtt
    57061 tggcaaaaac gtaaatacgg ttcgcttagc gctaactaca ttggcaaatt tcaacatgat
    57121 tgatctaagc agtgatggac taattgccat cagtaattgg gaaaaacatc aaaatatcga
    57181 gggtatggat aaagtaaggc taaaaaatgc tgaaagaaac cgtaaataca gggaaagaaa
    57241 gagacaggaa cgtctcaaat tggaaaatga cgttagcgtg acgtcacgtg acggtacaga
    57301 taaagatata gaagaagata aagatataga taaagaagaa aagaaaggta agtattctga
    57361 cgaacactta cgccttgcta aaaagttgca aagtaattta actgaagatt ttccaaaaga
    57421 aatgaacaaa gtagatatcg aaaaatgggc agacacaatc aggttgatgg aagaaagaga
    57481 taaagcatct atagaagcga ttgagtatgt gatcaattgg ctacctacaa atgaattttg
    57541 gtttggaaat attagaagtg ctaagaaatt gagagaaaaa tttgagaagc tcaaattcga
    57601 aatcaaagca gacaagaaga atcataaaaa gcaaagtcaa aaactacagt acagcaatcc
    57661 tagtgaatat gacgacttgc caatttaaaa aggagatgca tcacatggaa agcctagcaa
    57721 atgctatgga gaaactaata agaagagtat tagtgcaaag cggaaaatgt ccagaatgta
    57781 gcgaaccttt gtatagttgg cgagctaaaa ataaggatgg ttcagaacgt tgtaaaccaa
    57841 catgcatgag ttgtggttat aaagcgttac gtgtgaaaga ggatatacag accgaacgga
    57901 tatataacga tagcttaaaa gcacgagcgt tgagtttttt tcaaaatggt tcggtattaa
    57961 cagataaaac tttgtttaaa tgcaaaatgg aaaattatca cgtagtggat caagaaacaa
    58021 aaatcgcttt agaaaaagca aaaagctata cgaatgaggt tctgctgaac catcctgcac
    58081 atttcattct atcagggaaa tcaggaagcg gaaaaagcca cttatcaatg gccacagctt
    58141 gggaaatact tgagcgctca aattatgaca agaaaatact ttttataagc tatcaagaat
    58201 tattagagca aataaagttt tcttataaca atactgaact gagaaaagaa attgaaggat
    58261 cgcttatagc cgatattaaa acaactgatt tggtggtttt tgacgatatt ggagctgaat
    58321 taggtagtgg ggtatcaaat agtaggcagt ttacaaacaa cacgttaaac acgctcttag
    58381 aagccagaca gaacaaggca acgatcatca caacaaactt atctggtcct gaactaagag
    58441 aagcctacgg tgaaagaatt gtttctagga tatttaagaa ttcagaaggt tatgcgctga
    58501 aattccaaca aacagcagac aagcgcataa aaccagtgaa aggtagtatc gcatgaataa
    58561 ataccgtaat aaaaaaactg ttcatcgagg tatcaagttt gattctatcg cagaagcaga
    58621 gtattacgat ctagccttgt ggcaagctga agcaaatggc tggaaagtaa aacttcagga
    58681 aagatttgag ctgatgccga aatttgaact agacggaaag aagtatcgca agatcgagta
    58741 tattcccgac ttcacatttt ataaaaacgg caaacttgtc aaagtcgtag atgtcaaagg
    58801 aatgcagaca aaagacttta agatcaaggc aaagttgttc tgtcatcaat atcaagcgcc
    58861 gttgatatta gctaaaaaat atcggaatac gttcaaggaa gagcgttttt aacgaggtgg
    58921 tccatcatga caacagaaga agtgattcaa atgcgtattc gaaacattca gcgtgaaatt
    58981 gacgatctag aacgaacaaa ggcagtgatg gtcaatgaaa cggcgagaaa ggcaatcgat
    59041 ttgcacatag agaacttaag aagggaaat
//
LOCUS       DAFEKH010000012        56387 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.013, whole genome shotgun sequence.
ACCESSION   DAFEKH010000012
VERSION     DAFEKH010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 56387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56387
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.013"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            330..1175
                     /locus_tag="LP386_000822"
     CDS             330..1175
                     /locus_tag="LP386_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL1918080.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1456..2676
                     /locus_tag="LP386_000823"
     CDS             1456..2676
                     /locus_tag="LP386_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HBL1918081.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2673..5393
                     /locus_tag="LP386_000824"
     CDS             2673..5393
                     /locus_tag="LP386_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL1918082.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5377..6321
                     /locus_tag="LP386_000825"
     CDS             5377..6321
                     /locus_tag="LP386_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBL1918083.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6390..7400)
                     /locus_tag="LP386_000826"
     CDS             complement(6390..7400)
                     /locus_tag="LP386_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL1918084.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7580..7924)
                     /locus_tag="LP386_000827"
     CDS             complement(7580..7924)
                     /locus_tag="LP386_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBL1918085.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7917..8351)
                     /locus_tag="LP386_000828"
     CDS             complement(7917..8351)
                     /locus_tag="LP386_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HBL1918086.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8489..9226
                     /locus_tag="LP386_000829"
     CDS             8489..9226
                     /locus_tag="LP386_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1918087.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9219..10430
                     /locus_tag="LP386_000830"
     CDS             9219..10430
                     /locus_tag="LP386_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1918088.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10634..11416
                     /locus_tag="LP386_000831"
     CDS             10634..11416
                     /locus_tag="LP386_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HBL1918089.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11486..12148
                     /gene="trmB"
                     /locus_tag="LP386_000832"
     CDS             11486..12148
                     /gene="trmB"
                     /locus_tag="LP386_000832"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HBL1918090.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12246..14000)
                     /gene="ade"
                     /locus_tag="LP386_000833"
     CDS             complement(12246..14000)
                     /gene="ade"
                     /locus_tag="LP386_000833"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HBL1918091.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            14132..15061
                     /gene="tadA"
                     /locus_tag="LP386_000834"
     CDS             14132..15061
                     /gene="tadA"
                     /locus_tag="LP386_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HBL1918092.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            15018..16067
                     /locus_tag="LP386_000835"
     CDS             15018..16067
                     /locus_tag="LP386_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HBL1918093.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            16064..16342
                     /locus_tag="LP386_000836"
     CDS             16064..16342
                     /locus_tag="LP386_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBL1918094.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16317..16787
                     /locus_tag="LP386_000837"
     CDS             16317..16787
                     /locus_tag="LP386_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HBL1918095.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16804..17106
                     /locus_tag="LP386_000838"
     CDS             16804..17106
                     /locus_tag="LP386_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918096.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            17123..17494
                     /locus_tag="LP386_000839"
     CDS             17123..17494
                     /locus_tag="LP386_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HBL1918097.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            17466..17825
                     /locus_tag="LP386_000840"
     CDS             17466..17825
                     /locus_tag="LP386_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918098.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17997..19004
                     /locus_tag="LP386_000841"
     CDS             17997..19004
                     /locus_tag="LP386_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL1918099.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            19029..20213
                     /locus_tag="LP386_000842"
     CDS             19029..20213
                     /locus_tag="LP386_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HBL1918100.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20650..22233)
                     /locus_tag="LP386_000843"
     CDS             complement(20650..22233)
                     /locus_tag="LP386_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBL1918101.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22811..22954)
                     /locus_tag="LP386_000844"
     CDS             complement(22811..22954)
                     /locus_tag="LP386_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HBL1918102.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(23177..23656)
                     /locus_tag="LP386_000845"
     CDS             complement(23177..23656)
                     /locus_tag="LP386_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBL1918103.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23729..24013)
                     /locus_tag="LP386_000846"
     CDS             complement(23729..24013)
                     /locus_tag="LP386_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918104.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(24091..24285)
                     /gene="ssrS"
                     /locus_tag="LP386_000847"
     ncRNA           complement(24091..24285)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="LP386_000847"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24357..25643)
                     /locus_tag="LP386_000848"
     CDS             complement(24357..25643)
                     /locus_tag="LP386_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HBL1918105.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25781..26452
                     /locus_tag="LP386_000849"
     CDS             25781..26452
                     /locus_tag="LP386_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HBL1918106.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26418..26906
                     /locus_tag="LP386_000850"
     CDS             26418..26906
                     /locus_tag="LP386_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HBL1918107.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26919..27866
                     /gene="prmA"
                     /locus_tag="LP386_000851"
     CDS             26919..27866
                     /gene="prmA"
                     /locus_tag="LP386_000851"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HBL1918108.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27867..28631
                     /locus_tag="LP386_000852"
     CDS             27867..28631
                     /locus_tag="LP386_000852"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HBL1918109.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28864..31077
                     /locus_tag="LP386_000853"
     CDS             28864..31077
                     /locus_tag="LP386_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HBL1918110.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            31088..31534
                     /locus_tag="LP386_000854"
     CDS             31088..31534
                     /locus_tag="LP386_000854"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HBL1918111.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31705..32964
                     /locus_tag="LP386_000855"
     CDS             31705..32964
                     /locus_tag="LP386_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HBL1918112.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(33053..34000)
                     /locus_tag="LP386_000856"
     CDS             complement(33053..34000)
                     /locus_tag="LP386_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBL1918113.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34394..35686
                     /locus_tag="LP386_000857"
     CDS             34394..35686
                     /locus_tag="LP386_000857"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HBL1918114.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35701..37470
                     /gene="aspS"
                     /locus_tag="LP386_000858"
     CDS             35701..37470
                     /gene="aspS"
                     /locus_tag="LP386_000858"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HBL1918115.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37579..38454
                     /locus_tag="LP386_000859"
     CDS             37579..38454
                     /locus_tag="LP386_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL1918116.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38720..40603
                     /locus_tag="LP386_000860"
     CDS             38720..40603
                     /locus_tag="LP386_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBL1918117.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40678..40962)
                     /locus_tag="LP386_000861"
     CDS             complement(40678..40962)
                     /locus_tag="LP386_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBL1918118.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40952..41686)
                     /locus_tag="LP386_000862"
     CDS             complement(40952..41686)
                     /locus_tag="LP386_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HBL1918119.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41815..42438
                     /locus_tag="LP386_000863"
     CDS             41815..42438
                     /locus_tag="LP386_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBL1918120.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42630..43751
                     /locus_tag="LP386_000864"
     CDS             42630..43751
                     /locus_tag="LP386_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HBL1918121.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43758..46886
                     /locus_tag="LP386_000865"
     CDS             43758..46886
                     /locus_tag="LP386_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HBL1918122.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46905..50099
                     /locus_tag="LP386_000866"
     CDS             46905..50099
                     /locus_tag="LP386_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HBL1918123.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(50245..50952)
                     /locus_tag="LP386_000867"
     CDS             complement(50245..50952)
                     /locus_tag="LP386_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBL1918124.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            51717..52115
                     /gene="spxA"
                     /locus_tag="LP386_000868"
     CDS             51717..52115
                     /gene="spxA"
                     /locus_tag="LP386_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBL1918125.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
     gene            52447..53100
                     /locus_tag="LP386_000869"
     CDS             52447..53100
                     /locus_tag="LP386_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HBL1918126.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            53326..54324
                     /locus_tag="LP386_000870"
     CDS             53326..54324
                     /locus_tag="LP386_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HBL1918127.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            54500..56308
                     /gene="pepF"
                     /locus_tag="LP386_000871"
     CDS             54500..56308
                     /gene="pepF"
                     /locus_tag="LP386_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBL1918128.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
BASE COUNT        18555 a         9728 c        11685 g        16419 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt
       61 gaactaatag agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat
      121 agttggttat tataaaatag taatatagct gatttggatt caattcatat ttatttataa
      181 atcaaaaata cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta
      241 cttacttaaa ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc
      301 agtgaattta taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt
      361 tagacggtac tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga
      421 aacatttacc ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta
      481 ataatattct caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg
      541 gatttgatgg agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa
      601 ttgattctgt cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat
      661 ctcagaatta taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta
      721 tcaaagagct aaactatgag cttgagtatg aaaaatctat ttgttcaatc ccttataata
      781 atattgagga aattatagaa aaggatgcta tcagcattta caaatttttt atttttattc
      841 ctaatcgtca attgaaagct aatatattta accatttgaa aaagatgcta aatgtgtctg
      901 ttactgaatc ggcacctgta aatattgaaa tcgtacctca aaatgtatct aaaggtgtgg
      961 tgtttgatcg tttggaatca atctacaatt taaagaaacc tttgagaatc gcgatcggag
     1021 atagtttaaa tgacttatct atgtttgaaa gtgcagatat tagttttgca atgggaaata
     1081 gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt ttcaaatgat aaagacggag
     1141 tatctcaagc atttgaaaga attcttacca tataaactaa ttaaggtagt atagaacata
     1201 gaattctaaa tacggaaaaa tggagcataa attccagtac aaatagtact tcttcagtgt
     1261 caaacgaagc gaatataaca tagatattta ggattgtgac aaaaatcatg tcacaatctt
     1321 tttttcgaat aaacttattt tttgaagtcg gccatttatc gtaatttctt tacataatac
     1381 gaacaaattt tcggttattg atgaaaaaaa acattgaaaa tggtatgata aaagaaaaaa
     1441 aggaggaaat ttttaatggt gaaatttatc catgcggcag atttacatat ggatcggtca
     1501 tttgaaggac tgacaactct tgataaaact gtacaggaaa aactattgaa gacgaatctg
     1561 accgttttat caaatatcat tgaacaggca ataataaata acgttgattt tgttttactt
     1621 gcaggagata attttcatca aaatcgtcct tcattaaaaa tacagaaaca tttttcagaa
     1681 cagatgaaac ggttagaaaa gaaccatata cctgtattta taatattcgg aaatcatgat
     1741 ttctatcaaa aagagcggta ttggttctcc tttcctaaaa atgtccattt atttacatcc
     1801 gaaacggtag agacaaaaaa aataacgata aaaagtggag aaactgtctc tctcagtgga
     1861 tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga tggaatttcc ttctagagaa
     1921 ctcacagatt accatattgg gttgtaccac ggggaacctg gcgtctctca aaaaggaaac
     1981 tatgctcctt tccaaccctc aaagatgcaa gaaaagggat acgattattg ggctttaggg
     2041 catatccatg tgccaacggt cttaaatgaa aagcaaacaa ttgtttatcc aggtgcgcct
     2101 caaggtcata ctaaaaagga acaagcttct acatctattc tactagttga attaagtaaa
     2161 ggaagttgcc aaatacatcc gattaaagta gcagaggtct attggaagac aaaggaaata
     2221 tcattgagga aagcaagaac gacaaaagag gtcattgttc acattcgtca gcagctttca
     2281 aaagtagagg atggatttag tttaattgag ataaaattaa aagattatga ccatctcaat
     2341 acagatgttt tggaacggat acaatcagga gagctattag actatttgtt agaggaattc
     2401 tcagatagga taaatgattt ctttatttgg cgtatttctc tcatagagaa tactttttat
     2461 acgaagaccc cacttgctgc ttctgctaaa ttgatggaac agttatttca atactatcag
     2521 acacctcaag atttccaaca aattttaaat gaagtatata gtcatcaaga agcggctaga
     2581 atattgagcg aactgccgga atatcaagaa gaaacacttg aaaaagccaa gcagctgctt
     2641 aatcaagatt ttttatttga ggaggatcag gaatgaagat tttaaggatc gagattgctg
     2701 cttttggaaa atggcgtcaa aaaagttttg acttttattc aggcaatcag ctgatctatg
     2761 ggggaaacga agcaggaaaa tcaacgattt atcaatttat tcaagcaata ttatttggtt
     2821 tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa agacggctca gcctatggcg
     2881 gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc tgtcgagcgc tacaagcagc
     2941 aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt gggaagtgat gagttactag
     3001 aaaaactgat cgcacctttg acgaaagagt tattccagca ggtatttact ttccagcaag
     3061 agcagttgat ggaactagat catttgagag aaaaagagct acatgatgcg ctgatttctt
     3121 taggcatcac gggcagttct caagtattcc aaaagcggca agaatattat cagaaagcac
     3181 aacaattatt caagaaaaaa ggccaaaaat tactaatcaa tcaaaaatta aatgaatgga
     3241 aagagctgca agaaaaaatt catcaaaaac aagaacagga agcttatttt ggcaagttga
     3301 tccaacaaga acaggaatac gagtcgcaac agcagcagtt attggcacaa ttaaaagagg
     3361 cgaacaaaca attttcatta gccagacagc aagaacttaa tttttcttta tatgaagaat
     3421 ggcaatctct caaaaaaaac agcactacag gtcttcctga tgagcaactt cttttagatc
     3481 tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg tttggaagaa ttagaagcaa
     3541 cactggaaaa gcatagcggg atggatcagc agtcagccag atattatttt tatttagagc
     3601 aggagcagga actaaaagat ctccagcaac ttcaatttac agcggaacaa ttaaacgaag
     3661 aatggcaaag attacaaatt gagactagag aaacaaattc agaattgaag attttggaac
     3721 aaaggtggca ttggcagaaa aatccgttac cggaagaatt tttatatgaa gaagaatgga
     3781 agcatcttct ggctgaagaa agaaggattg ctgatctaga aagccagatt tctgtgcgtc
     3841 tccaaatagc taaagaacag caagagatga ttgaagcaga agtgaatgac ttggaagaga
     3901 cctatccagc attattacaa aatcagtcag agatagcacc agtctcttca tctaaaccgt
     3961 atatgctgat ggctggcgga gcaataatca ttgcaggtat atttgtacca atgcccttga
     4021 aagtgatcct tttactaatt ggtgcaggca tgattggcta tttcttctac aaaaggcaac
     4081 caaaaattaa aactaaaaat gatttctctg agataaaagg aatgtggcaa gaaaaactag
     4141 gacaacttga tctagcctta gctcaattag ctgaagcaga agaaaaacaa aagagaactg
     4201 gagaagaaaa acagattctt cagcaagaag tatatcgttt tgcggatcat cggcacttag
     4261 gaaagatgga tacgctcaaa ctcatgaaag aatatggaca ggaagtcata gattatcaga
     4321 aattatatgg cgtatttgag cggaaacata aaagagaaca ggaaatacaa gaaaaactac
     4381 gacaaatcga ccaaaaattt gagtttgtta aagaatggtt accgatacaa gataagacaa
     4441 tttcagaaaa aatggtattg ctttcccgtt ttatacaaga gatggaacag atgaaatttg
     4501 ccagaagcta tcagcaaaat actttattga agcaagaaat caatcaattg aaaaagaaac
     4561 aaaaagtatg gatacaagaa tacagcgaac aattgactca agcaggctta tcttatcctt
     4621 cggaagtacc tgtcttttta caaaaagcca aacaagccga acagcagatg aaaagataca
     4681 atgaattatc ggaaatgctt actccactat ttcctgaaga gctgacaaaa gagaaattat
     4741 ctgtaagact gcgccaactg aaagaaaagc aatcccaact ccagcaagaa gaaaaagaag
     4801 caagtgaaaa tcggcaacga ctccaacttc aagtagaaga gttgcaaaga gacggcacat
     4861 tggacgaact ttatcaacaa gctagccggc aaaaagcaaa attacaggaa ttactggagg
     4921 aatggggagc acttgaaatc gccgggacat tcttaggtga tctttcaaca gagatgagtg
     4981 aaagacaatt accccagttg ttaagagcag caggtgatta tttaggtatt ttaacaaaag
     5041 gaaattatca gaagatatta ctgaaaaatg atacactgac tttaacagac ggatatacag
     5101 aatttcccat ctatgagtta tctacaggta cgaaagatca gctgattatg gcgatgagat
     5161 ttgcttacct ctcattagaa gctaaccgtt cgatatgccc gatcatcatt gatgatggct
     5221 ggcttcatta tgatcatcag cgaaagtatc aattagctga acttttagct aaatttggag
     5281 aaaagtatca aataatttgt ttttcttctg ataaagaaat ggtaagctat taccatgaga
     5341 tgaaccaaat cgtaaaacaa ttagaaggag caaataatga aaaaaattcg tgatttagta
     5401 atcgatgagc agtttgaaca atttgtcctg atcaaaagtg cagatgtaag aatcgctaaa
     5461 aacggaaaaa aatttattgc ttttactttc caagatactt caggtactat cgatggtaaa
     5521 tactgggatg cttcggagga ggaaatcaat aaatttacag ccggcacagt cgtttttcta
     5581 aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa agattcttca tatgcgctta
     5641 acaagggtag atgagccagg agagcctagt ttatacatgg aaagagcccc tttgaagaaa
     5701 gaagaaatgg aagaagaaat caatcaattg ttgtttgaga tcaccaatgc gcattggaat
     5761 cgtattgttc gctatctact taataaatat caaaaacaat tttttgagtt tccggcagca
     5821 aaaagaaacc atcatgcatt tgccagtgga ttagcttatc atactttgac aatgcttcac
     5881 ttagggaaat caatcgccga tgaatatcct gagctgaatc gagcattgtt gtatgctggt
     5941 atcattttgc atgatttagg aaaggtgatt gaactttccg gtcctatgtc gacagaatat
     6001 acgcttgcag gaaatttgat cggtcatctg gtattgattg acgaagaaat aactaaagcc
     6061 tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc tcgtattacg tcatatggtt
     6121 ttagcacacc atggcttatt agaatatggc tcacctgtac gtccaagaat aatggaagca
     6181 gaaatattac atcaaatcga caatatcgat gcttcgatgc agatgatgtt gacttcgatt
     6241 cgtcaaacag aaccaggaaa atacaccgat cggattttcg gtatggacaa ccgaagtttc
     6301 tatgtaccaa aagatttata gcaaaaattt atttttttca ttcaaaacaa aaaaagcgag
     6361 acataagtct tcgctttttt tgttttcttt tattttgatg aatcagttgt ttcttcagtt
     6421 gaagattctt ttgttgaatc agttgatttt gtgtcagaac tctttgttga agctgtagtt
     6481 tcacttgagt ctttcgtact tgatgaagtt gttgtgaatg cactcaacac attttcaaag
     6541 gcatcatctt tgatttttac atttgcatct tttaattctt caccgattac tttagttgtg
     6601 aatgcattgt cacttagttt agtttcagta gcgatatctt ttagttgatc tttgtattta
     6661 tccatgtcat tgcctttatt ttggtttttc accattttga caacgtagta ttctgtcgca
     6721 taagaagtag gatttgttgt agtaataaca tcggagatct caccgtcttt caatttgaaa
     6781 gctgcttctt ttacttctgc aggaatagtt gttgtcgttg agtcgaattt aactttaccg
     6841 ccatcttctt ttgtctctgt atcagttgat ttgtctttgg ctaatttaga gaaatcatct
     6901 ccatcatccg ctgatttttt cacatctttt gcttcatctt cacttgataa tttgatgatt
     6961 tgtgcttcta cttctggatg gaaagatttc caagcagttt tcaaatcgtc atctgtaata
     7021 tctacgtgag ctttcaagcc agcttcaaaa gctaaattgt tacgaatata ttctttataa
     7081 gtatctttcg tatatccagc agcttctaat tgtgattcaa aagtatcacc taatgatttc
     7141 gcttgtttgt cgtattctgc atccacttgc ttatcggtta ctttatcgcc atatttgtta
     7201 ttgaatactt tataaatgat catccgttgt actaaggatt ggttcgatga ttcaagtttt
     7261 gcttcatcat agaaatcaga tacagtgatc gttccgcctt tcatcgttgc gatatcttta
     7321 ttagtatcgc ctgaacaagc tgctagagtt aaaacagcca acgcactagt agctgccaaa
     7381 ataattgatt tttttttcat taaaatttgc actcctgtaa ttagttatta tttttatata
     7441 ttaactatac catatcccat ttcctttaaa aacgttgtcg tggtagtttc aaacaaaatt
     7501 caaaatttca tcacattcct aggaaatacg caaacttttc tcacttatat agttaaatct
     7561 gttgagaaaa taatcattat tatatttgtt caggatactc tggcagatca gcttttagtt
     7621 tttctacttg ttcattgatt tgtgtgatac gtggttcggc ttggaattta aaatcttcga
     7681 tatctttttt gattgcttct tggaaagcag gaatcacaga ttcagctgtt tcttttgttt
     7741 cgatcaatgc gcttttaaaa tgattcaggc tgttatttaa atcatttgtc agagttgttg
     7801 cttcttccaa ttcttcgatc agtttctttc ttgtttcatt cccgctcctg ggcgccaata
     7861 acagacctcc gacagtgcca gcagcagctc caaataacag tcctttgaaa aagtttttaa
     7921 tcatcgcagg acacctgctt tacgattgtt tcttgaatag cttttagttc ttccgatcca
     7981 taactatctt gatgattgac aaagtgaata gaaaaatcat cctctttgct gtagcgaggg
     8041 actaaatgga tatgtgaatg aaaaacagat tgataggcta gttcacggtt gttattcaag
     8101 atattaagac ctttcatttc tggaaaagct ttttccaatg cttgagcaat cttaggcaca
     8161 cgcgaaaaaa cctctcctgc aagttcggga tcatattcaa aaatatctgc tacatgacgt
     8221 ttaggcacaa ctaatgtgtg tcctttcgtt gcttgagaga tgtctaaaaa agcatagacc
     8281 ttgtcgtctt catatatttt atagcttggg atttcttgat tgatgatttt gcaaaaaata
     8341 cagttttcca tataaaacat cctttctata aagaataaat acttcagctt aactttacca
     8401 taagttaaag ctattgtaag gaaaaaaaca aaataccgtc attttcttcg tggtataata
     8461 aataaaaata aatggcggag gaaaaagaat gagtttaatt atcgatcatg tcacaggggg
     8521 gtacggacat ctccctgtgt taaaagatat cagtttcgat gtacagcctg gagagatagt
     8581 agggttgatt ggactgaacg gagcagggaa aagtacgacc atcaagcaca ttatcggtct
     8641 gctggaagct tcaaaaggaa cgatagaaat caatcatcta tccttaaaga aaaatacgga
     8701 agaatatcgc aaacaaattg ggtatattcc agagactcct tctttatatg aagaattgac
     8761 attgagagaa catatcgaag tcactgcgat ggcctacgat atacctatgg atatagcaat
     8821 gaaaagagca gaaaagttgt tggagacttt tcggttatct aatcgtcttg actggttccc
     8881 agctaatttt tcaaagggaa tgaaacagaa agtgatgatc ttatgcgcct ttttgatcga
     8941 gccttcttta tatatcatcg acgaaccatt tttaggcttg gatccactag ctatcaatgc
     9001 attgcttgaa ttgatggtag aaatgaaaaa agaaggagcc ggtattttga tgtctacgca
     9061 tattttagct actgcagaaa aatattgtga tcgttttgtg gtcttacata acggagagat
     9121 acgagcagac ggttctcttg agatgttgag aaaagaattt cagctgccgg attcttcttt
     9181 ggacgaaatc tatattgctt taacaaagga gcaggcacat gagtagtttt tttcaaaaac
     9241 gtttagcaag acatcaaaag aaaatgatga aatatatgcg ttatgtattg aacgatcatt
     9301 ttgttttagt ttgtcttttc ttgattggcg gtgtgggatt atattattct aattggttga
     9361 aaaccctgca gccaccgttt gcaattggag ggctcataat ctctgtattt tggatgctct
     9421 gtttattcgt gggtaagatg gctacttttg cagaggcagc agatattgtt tttttacttc
     9481 ctaaagaaaa agaaatgcaa acctatttgg aacgagcttt tcgctattct tgcatttttc
     9541 cgttgatctt tttgatattg gcatgcggat tggccatgcc attagtggtg gttagtacgg
     9601 agcaatcctt ttcgatgttt ttcgtctatc tgatcatatt atggagtttg aaattcagtc
     9661 atctgcaaat caagagagca gaattgtttc gactagatca acaagttatt cgttattgga
     9721 aattaggctg gtttttttct tctctgatct ttttgtttct atcattttat tggctaatat
     9781 gggcaggaat agcaggtgca ttagtacagg caagtctata ttactggttt ttgtggaagc
     9841 aacaagaaaa aggattggat tgggagaaaa tggtgcatgt agaagaacat aggttgcatc
     9901 agatctatca atttatcaat ttattcacag atgttcctga aattacggca aagatcaaaa
     9961 gaagacgcta tttggatcct atattgactc atattaaaag agaatcaaaa aacacttatc
    10021 tttacttgtt tgcaagaaga ttggcaagag gttctgattt tagtggtctt tatttccgat
    10081 tagtaattat aggtgggtta ttgattgccg gagtagtcga cttttatttt agtctgatta
    10141 tcggtttctt atttttatat ttgatcggtt tccaactgtt acctttagcg aaccagttcc
    10201 gctatatggt tctcgttcag ctttatccaa tccataagaa tcagaagaag caggcgattc
    10261 agtatctact cacatgggta ttaattatcg cgtcggttat ttttggtttg attgctgcag
    10321 tcgtattaga tgggcagcag cgatgggttc cgctagcggc ttatttgatt gttactatgc
    10381 tctttgttaa actatatgta ccaactcgtt tgaagaagat gtcagactga aaacaaagct
    10441 gtgtagggta aaaatgagaa tgaaaaatag agcgttgaca gtaagaatgc tgttcgttct
    10501 attttttttg agaaaagctg gttttttgaa tggcaattaa atgaaaaaga acgtatatgt
    10561 gcttgacgtg tagtgttcag gcgactagaa taataagtac tgcaaaacaa agagtaagag
    10621 gacgggagaa tgcatgatgg agtttcagtt agaccaagag tggcggttac gtcccatcaa
    10681 aggcgacaca ggaaaaacat acataggcat gcgtgatgag gacaaagtct ttattaaacg
    10741 aaacacgact ccgatgttgg ctgctctttc aagggaagga attacaccaa aacttgtttg
    10801 gacaaaacga acggggaatg gcgatacttt gacagcacaa gagtggctgg aaggtcgctt
    10861 gctgactcct aatgagattg gtcaaagaaa cgacgtgatt gatgttttgt accatttaca
    10921 tcattcaaat tctcttaaaa ccatgctgac ccgtatcggt ggtcgtgtca tgacgccgga
    10981 gaagatgctg caaaaatatg aaaaagaatt accggaagaa ctccagaaaa atcaatttct
    11041 gcaaattgtc catcgttttc ttcgtgagca gatcccgtca atagataagg aaaacttatc
    11101 agtagtacac ggagatgtaa accatcgtaa ttggttagta tgtaaaaatt atttatatct
    11161 agtcgattgg gattcaatca tgtttgcaga ccctgcggtg gatattgcaa cgattttagg
    11221 aaattatgtg ccactgtcta gctggaatca gtggctgatc agttatggca tacgcccgac
    11281 tgacgaaatg cttgaaaaat ttcattggta tgcggccatg aatttgctcc aagaaatcac
    11341 cagatattgc aaacgtgaag atcatcgacg gatgaacgaa gaaattttac aattaaaacg
    11401 aattttcagt ggctgaggtt tggcccaaac tctgcggaga tttggccaga cctttttaat
    11461 tagaggaaag gaatggagat aaataatgcg tgtccgaaat cgtccgggag cagcggaaat
    11521 gttagcggct cacccgaatt ttgtaattag tgatccaaca ttgtggaagg gaaaatggaa
    11581 tgaattgttt gaaaacgatc atccaatcca cattgagatt ggtatgggga aaggccagtt
    11641 catcactgga atggcaaaag cccatcctga aatcaattat attggagtag aaatgcaggt
    11701 cagtgttgtt tcgattgcac tagacaagtt gatcgaacaa ccgcttccta acctgaaact
    11761 tctacatgtg gatggatcag cgttgacaga gtatttcgct gacagcgaag tagatcaaat
    11821 ctatctgaat ttttccgatc catggccaaa aaaacgtcat gaaaaacggc gattgacata
    11881 taagactttt cttgctgtag atgaacagat tcttcgtcca aatggagaaa tccatttcaa
    11941 aacagataat caaggattgt ttgagtattc tctggcaagt ttttctcaat atggcatgat
    12001 cctcaaacag gtatggttag atttacatca aagtcaattt gaaggcaata ttatgacgga
    12061 gtatgaagaa aaattttctt caaaaggtca acgtatttat cgagtagaag ctcaatttca
    12121 agataagacc aaaaagaaaa gtctgtgaaa ctaactttct gctttcataa aaacattaat
    12181 atccataaat aaatcccaga aaatgaacat tacagatgta atgtattttc tgggatttat
    12241 ttgatttaaa atgtatttat ttcatcggtt tttccacaag gtggaatcaa ttggaagcga
    12301 gaaaatgaaa ataatccttt gtcggtgatc ttcaattcgg gtatgacaga taatgttaag
    12361 aaagaaagtg tcaaaaaagg atcaaaggtt ttagctgctc ctagttgatg tgctttagtt
    12421 attaattcat tcaactgttc atagacgatc gaaaaaggtt cctgtgtcat gattccgcct
    12481 ataggaagag aaacacaagc tatttcctgc tgtttgttga caacggtcat cccgccacct
    12541 ttttgaatca aaagattagc agcatacagc atatcctcgt cgtttgtccc aacgacaact
    12601 agattatgcg agtcatgggc aatcgttgtc gctatcgctc cttgtttcag ctgaaatcct
    12661 ttcactatgc ctaatccaat gtttcccgtt tgatggtgac gctcgatcac cgcaatcttt
    12721 aattggtctt tttcgattga aggaatgaat cgttcgcctt gtcggtccac tttttctacc
    12781 aaatctttag tcactagact attcgggata atttcgatca catgggcttg tgaagaagaa
    12841 agaagcagct ctaacgaatg tggatttaat ggttgagcgt ttagttttgg cagacaacac
    12901 gtatatgaat ttgaatgatc agcaaataaa tggtcttgga gttgcccaga ttgaacaact
    12961 aatgttccct tatagaaaac ttcatgaatt ggcagcttgg taagatcgtc tgttaagaag
    13021 aaatcagctt gatacccagg ggcaatcgca cctagtgttt tcaaatcaaa acattctgct
    13081 gcattcaatg ttgccatctg aatggcttgt aatggatcga ttccaagtgc aatagcttga
    13141 cggacgatat gatcgattga tccttctttt actaaatcat tgatcagttt atcatcggtg
    13201 acaaagaagc atcttcttga attttcaggt gtgatcgccg gtagtagcga tgccagatct
    13261 tttgcaacgg tcccttctcg aaccattaaa tacataccaa gatccaaacg ttctttagct
    13321 tcttttgcag ttgtagcttc atgatccgtc cgaatacctg ctgcaggata aacatttaac
    13381 tcttccatgc cgataccagc tgcatgcccg tcaatttttt tcttatgctg gtgcatcaat
    13441 tggatctttt ctaggatgtc tgtttcatta tttgctactg cttgatagtt catgacttca
    13501 gctaagccta aaacttcggg tttttgtaaa aaaggggcta atttttttgc atttaaattt
    13561 gcaccattgg tctcaaaagg ggttacaggt acacaagaag gtagcataaa aaagatattc
    13621 atgagtgttt gtcttgcatc ttctatcata aactcaagac ctgtactccc agcaatgttt
    13681 cctatttcat ggggatctgt cactacagta gtaactccat gaagcaagga tacttttgaa
    13741 aattcgcttg gtgataaaag tgagctttcg atatgcacat ggccatcgat gaatcctggc
    13801 actagatatt gcccattagc attatgtacg ctttttcctt cgtattcacc gattcctacg
    13861 atcattcctt cgcagattgc tacatctttt tccatgattt ctttcgtaaa gacgttgacg
    13921 atcttagcat gcttgatcac taggtcagca ggcttttttt tacttgctac ttcgatatat
    13981 ttccttaatg ttgtttccaa tggagtgcct cccaagataa atttttataa gtataacata
    14041 aattcggttt ttgccaatat ttttttgtaa attcatttta tttgaaacaa aaagatcaaa
    14101 aagacgtatg ttttttgtgg aggggagaat aatggaaata aaacgattat cggatcaaat
    14161 gataagtgaa agttttgcca aacatgccca agacgtatat atattgccag cttcagaagt
    14221 attttacatc tattttcgct atggaaaaaa acgaacattc tggaagaaag tctcttcggc
    14281 agatggacag caactgatct caagatttaa gtatttggga cagatggata tcggagaaaa
    14341 aagaaaagct cagttaggtg catttactta ttctttagaa aaacaggaag ttcgtctgcg
    14401 gttgtcttct gtaggagatt accttcaacg agagagttta gtgattcggc tattatacgg
    14461 tacttttgaa acaccccatc gttgctttag ttctcgagat tttgcaacta ttttacagaa
    14521 aaccgtcaga cgtggattat accttttcag cggaccagtc ggatcaggca agacttctct
    14581 aatgtatcgg ttggctttgg aagaaaaatt gcaagtgatt actatcgaag atcctgtaga
    14641 gatagaagaa ccgttttttc tgcagctaca gatcaatccg aaaatagcac agacttatga
    14701 tacacttttg agactcgcat tacggcatcg tccagacttg ctaatcattg gcgagataag
    14761 agatgaatca actgcacatg ctgcggtaag agcagcacta acagggcacc gggtttttgc
    14821 aaccgtacat gcacgcaatc ttgaaggtac attggtcaga atccatgaac tgacaaagaa
    14881 aaaagaagag ctatctgaat gtttagctgg tgtcatttat caagaacttt tggaagatgc
    14941 caatcaccat ccttctgttt tatggagtta tcaatttatg gaggaagaat cagtaaaaaa
    15001 atcatgggag gaaagttatg aagaagctca ggaaaatatt tggcagtcag aactattcta
    15061 aaggattaac aagaagccag caaaaccagt ttgcacaaac catgggagaa ctgcttttat
    15121 ctggttttag tctgcaagaa tccctttatt tattactcac gatccgttcg tttccacctg
    15181 ttattttggc aaatatccaa catcagctaa aggaagggca agcgtttagt gaggtacttt
    15241 cgcaaatagg atatggagca gagcaactgg tacagatcga gttagctgaa cgtcatggga
    15301 atctgccgac aactttgttg gaaattgcca aacagtttcg gcttgttgaa ggatttcgca
    15361 atgatttgaa aaagctgctt gcatatccga tgctattgct cacctttttg ctaggtatct
    15421 tgtttagtat gcggttgttc gttttgcctc agcttattgg ttcaggaatg gtcatgcaag
    15481 agcattgggg tattcagctg atacaagtct ttcattggta tgttctacta ttcatcctag
    15541 cggttactct attggcttta ctagtaaggt atcgtctgat gaagttgtct cctgttgatc
    15601 agagtgaatg gataagcaga caattattga ttggaccgat atattccttg tatcaatcgg
    15661 cttatttgtc actagagatt ggaaagcttt ttcatgaagg tttcgaatta aggcaaatca
    15721 tagtctgctt aaaggaaacg aaacaagaaa gtctgattca gcatcttgcc tctaagttga
    15781 ttcaaggatt ggaggcaggt atgtcattgg ctgagcagtt ccagaattat cgttttctat
    15841 cagaagaatt cagtaaaatt gttttacagg gagaggcaaa gggaagttta ggtaaagaac
    15901 tgatttttta cagcgaatgg acaagaaaac agcttttcaa acgtcttcat cactggatgc
    15961 attttattca gccaatcatt tttttgggcg tagcggcttt gattttatta gtttatgccg
    16021 ctgttttatt acctgtttac ggaagcatag aggaggtttt gccatgaaaa agagaaaaat
    16081 atcttattat agcggtttta cattgatcga aatgctaatc gtcttactga tcatcagtgt
    16141 attagtgttg ttgttcgtcc ctaatttgtc gcgttatagg aatcatgtag accaagaaag
    16201 tcgtgaagcg atcatccagt tggtagacac acaaaaagag ctctatgcgc ttcaaaataa
    16261 tggaagagtt cctactgtgg aggaattgtt gaatgaaggc tatatcaaac gagaacatgc
    16321 agaaatctat cagcggcctt gaaggtaagg ttttagcatc aggatatacg ttgtttgaat
    16381 cactcttact gattttatta cttacaacga tcctttcttt tccagttctc gcattttctg
    16441 catggaagaa tgaattggca gtctatcaat ttttcggcca atttgaaaaa cgaatctatt
    16501 ctacgcaaaa aatcgctatt gtgaatcaga tccaaacagg cttttattgg aatagtgaag
    16561 agaatcaaat catttttcat gttccgaatc cagataaaat aaattgggaa gtattagata
    16621 ttcctgatga gattaccttg aaacgccatg cttctattac ttttgctgct agaaccggga
    16681 atgaaagttc actaaaagct tatcaatttt attgggaaga aaaagagcgg acgattacgt
    16741 atcaattcca gatagggagt ggtcgctata caaaaagaat tgaataaaac aggatttgtt
    16801 ttgttggagt cccttacagc gcttatgatc gcttctgtct gtgtctactt agtgagcttt
    16861 ggccagctgt ttttgcttca ggcagaaaag aaaagtgggg aggaactgct atttattcga
    16921 atgatttatg aagatatcaa gacgcagcgg atgtatcaca aaagaccaga gcgaagggaa
    16981 gaaatgatcc catacgatat ccaaattgtc gataataatg gagtaatcga aaaagtgttt
    17041 gtcaatatgg agaaagaagc gatcagtatt gaaaaaacaa gtaattccag catttacgct
    17101 gattgaatgt ctaattggac tgatgatatt gagcagtcta ttgctcacat tcaatctttt
    17161 gattcagcaa accatccaag taagtgaatt tttgcagcgt aaagatcaaa aagagtggct
    17221 aatattttta gcacaattag aagaagaact caagagcagt cacaatgtct ctgtgaaaaa
    17281 tcagcaactg cactacacga tcgaggataa acagtatatc atcgaaagat atcaggcaat
    17341 gatacgtaaa agaagaactt ccggcggaca tcaacctatg ttaacaagta tcactgagct
    17401 tcaattattg gaaaaagaac acacaatttc tttttatgta cactttgaaa atggagaaga
    17461 tggatatgcc atatggacaa aaaacgatca gtagaaaatg ttataagggc tctattttat
    17521 tttctgtctt gcttttattt cttttatgta cgtttttatt gatggcagca ttagaaagct
    17581 accgtttgtc aatggatctt aatatacgaa tcaaaaatta ttatatagca aaaataatga
    17641 agcagatggc tttatcggaa cagtctacgc ttgccgaaag ttcggaagga gttttttact
    17701 acacaactgg atctgtaaca tatcagtggg tacaacagtc cctattctta gaggtggaag
    17761 tctcaccgtt tatctttcgg ttcacagaag aagtaaaaaa tgatacagat actagtacag
    17821 aatgatggaa tgttcgtgaa aacgccctct tttctgttat aacactgttt ttaataaaaa
    17881 aatgtttgcc gtttcacaaa taaaaaacag tgaaaacgat tgaaattttg tcaattgttc
    17941 gatagaatta aacaggtgaa aaaattgtta taatatatct agaaatgagg tgcaccatgt
    18001 taccagaaaa aatggaacaa gggtttaatc aaaacctgga agctattcag cttttacaga
    18061 atgcattggg aacttccttt ttagaagcct atgtcgaaaa tgcagaaaat ttaatagatg
    18121 attatcaagt acgtgtggtg gatggagtgc cgacaaaaga gacaacgcaa cggatcacag
    18181 ctctttatga agagttgaag aaactttctt tcgagccaga agaatggcgc agactgtctc
    18241 aattactttt attgaagggc agccagacag aacatttgca ggcgaaccat caactcactc
    18301 ctgatagtat cggtttttta tttgtttttc ttattgaaca actatacaca aataaaaaag
    18361 caccggttaa gattctggat attgcggcag gaatgggcaa cttgttatta acagttcttt
    18421 taaacctatc gaatgcgggg taccaaacag aaggaattgg tgtggatatt gatgatacat
    18481 tgttggctgt cgcagcttct acaagtgatt tgacacaagc aaatgttcaa tactttcatc
    18541 aagacgggtt gcaggaatta ttaatagatc ctgtcgattt tgcaatcagc gatttgccaa
    18601 tcggttatta tccgaatgac gaaaaagcaa aagagttttt aacaagtacc gaagaaggcc
    18661 atagttatgc acatcattta ttgctagagc aatcaatgaa atatgtgaag ccggatggtt
    18721 ttggtttgtt tttgatgccg agtggatttt tagaaacgga tcaaagtgaa gaaatcaaaa
    18781 aatggtttaa agaagaaggt tatcttcaag gaatgattca attgccagat gaattgttcc
    18841 gtaataaaca atcgcaaaaa agtattttga tcttacagaa aaaaggacca caagcacaac
    18901 aagtaaaaga agtcttgctt gtgaaacttg cttcattaaa agaaccagag aaggtgacgg
    18961 aatttttcaa cgagtttaaa aactggaaat catctgctct gtaatcattc aacgagaagg
    19021 agagtcatat gtctaaaaca attgcaatca atgctgggag ttcaagtttg aaatggcaat
    19081 tatatcaaat gccagaagaa accgtagttg cgaaagggat cgtcgaacgt atcggtttac
    19141 aagattctat ttttaccatc aagtacggcg ataatcaaaa attcgaacaa atcatggata
    19201 tcgaaaacca cgaagtagca gtaaaaatgc tgttagatca gttgattgaa ctgcaaattt
    19261 taagctctta tgatgaaatc accggagtag ggcaccgtgt tgttcacgga ggagaaactt
    19321 atggggattc agtagtgatc gatgagaaag taatggaccg cattgctgaa ttagcagaat
    19381 ttgctccttt gcataatcct gcaaacttaa tggggatcaa agcgtttaaa aagattttac
    19441 ctgacatttt gagtgtggct gtattcgata catctttcca ctcaacaatg ccaaagcaaa
    19501 attatttata tagcttaccg gtgtcttatt atgaagattt caaagtaaga aaatatggct
    19561 tccatggcac aagtcatcgt tatgtgtcgg aacgtgcggc aaaattattg aacaaaccga
    19621 tcgaagaact aaaaatcatc acttgccact taggaaatgg tgtatcgatc acagcagtcg
    19681 atggaggtaa atccatggat acttctatgg gattcacacc attagctggg gtgacaatgg
    19741 gtacacgttc aggtgatatc gatccagctg ttctcccata tttaatggaa aaattagaga
    19801 ttgatattga tgaaatgatc aatgttttga acaagaaatc tggtctgcta ggcctaacag
    19861 gattgtctag tgatatgcgt gatcttgaaa agaactatga aaaagaacat attcgtttag
    19921 cttatgacat tttcgtggac cgcatccgaa aatacatcgg cggttatgtg acaacgatga
    19981 atggtgttga tgcaattgtc tttactgctg gtatcggcga gaatgacgga catgtacgta
    20041 gtgaaatcat caaaggtatg tcttggtttg gttgtgaaat cgatccagcg ttgaatgaat
    20101 tgcgtggtga agaagtagat atctctacaa aagaatcaaa agtaagagta ttagtgatcc
    20161 caacagatga ggaactaatg attgcccgtg atgtggagcg tctgcgcggc taagccaaag
    20221 cattcgttag gataaaagat gaaacgcatg caagagggaa ttcttgcatg tgtttttttt
    20281 gcggagaaga ccgcaaaatg gtaatttaac ttcaatttcc cttctttttt acaggatctt
    20341 cttagggaat tttgcttgga aaagtggtca aaagggaaaa gactggcatt ttatttattg
    20401 attttcagga aaatcccaat attttatttt cattcatctt tataagggac attacatatg
    20461 taaaaagaaa aaacattttt agatcagcct cgtgggctgt cgactttatt cttcgcttta
    20521 tgtttagcta gaaaaccgat ccgaaacatt cattgatcga ataataaaaa cttgattttc
    20581 cacctgtact ttgcctgaat cgtgaaagca caggtatgaa aatcaagttt tttgttgcga
    20641 aaaaacgtcc tagtcaatca gttggccgag cggctggcgg ctgatctgct cctgatcaat
    20701 aacgagtgct tcttggaagt gttgctgcaa aaagtagcgg tcatggctga ctgctaggag
    20761 cgttccttga tagtcttgca gcatttcttc aatttcttct cgagcatagc tgtcgaggtg
    20821 attggttggt tcatccaaaa tcaggacgtt gattttttct aaaaagagtt tcagcaacgc
    20881 caaacggatt ttttcaccac cggataaatc tttgatccgt ttacccacat cgctttgata
    20941 aaagccactt ttggctaatt gccgtcgagc gacttcttcg tttccagtca atgtgatggc
    21001 gtaagccagc aaacggctat cgggatcggc aaactgcagc tgctgcggca aataaccgat
    21061 ttgcaagcta ctacctaatt tgatggtgcc accgtaaggc ttttcctcac cgagtaataa
    21121 tttgagtaag gttgattttc ctgcaccatt gtcgccgatg atggctaaat gatctccacg
    21181 atagactgca aaactgctgt ctttgaatag tacttgatca gcgtactgct ggtgcaagtt
    21241 ttgaatgatg aaaacttctt tgccagattt tccaccatta gacaagcttt gcagccgatt
    21301 tttcggggga ggtggcggtt tgacgagtgt cagtttcgcc aggcggcgtt ccagttcttt
    21361 ggcttttttg aagaaggact cattgtctcc ttcatgtgcc cactgacgaa aacgacgaat
    21421 catgactttc aaccgctgga cttctttttg ctgcagttcg taattttttg tcagctcagc
    21481 caagcgagct tctttcaaga ctcgaaaacg gctgtagttt ccgggatact caatcaatgc
    21541 accttcttcc agttcccatg tttttgtggt gacttgatcg agaaattgcc gatcatgaga
    21601 aacgaccaga accgattttt ttgtattctg taaatagttt tccaaccagc gaatactgtt
    21661 aagatctaaa tgattggtcg gttcatcgag taaaagtaaa tcggcatcgg ctgctaaaat
    21721 tttggctaaa gcgactttaa ctcgttcgcc tccgctaagt tctgttaacc gtgcttcctg
    21781 acggtgtgga atccctaagc cttgcaagat cgctgcaatc cggtcttcta atacgtaacc
    21841 gcctagttct tcaaagcgat gctgcagctc accgtaacgg gccagacact tctctaagtt
    21901 tgtatctggt tctgtcatca atgcttcgta gcgactcatt tgctgtttga ggtcctgtat
    21961 ctcagcggca gaatggagca agtagtggtt gacggtcgct tcggaaactg taagttcttg
    22021 ttcgaccgtc ccgatcttta agcctttttt gcgactgata acaccgctgt cgacaccttc
    22081 tctgccggtc aagatttgta aaaaggttga tttgccagtt ccgttgatac cgactaaggc
    22141 aattttttca ccagcttcaa tttgacagga taaatcctca aataatggat tcccgccgat
    22201 tgttttttta atagaaattg cttgtatgat catgatctct ctccttgaga ccactcaaaa
    22261 aggccatggt tatccatggc ctgtgttatt taaactcaga ttatcatgag aaaaatacct
    22321 tgagatggcc attgatttta cgtgaattca actgttttgg acaaacttgt cccgtcaaca
    22381 gcaactgtaa aaccaattgc atggctaaat gcgatatggt atcgttggta attttcatta
    22441 cttgttattt tagtcatgcg catcatagta ttttccctcc ttcgtgtagt tgtcttttcc
    22501 agtgtacctg aaagtgtcag aaagttcaac tagcgctgac atttacttaa tatttatcga
    22561 tgtgtaattc tgtcagagag ctttttttat ctgactgagg gtaatgtctc gtggaccaca
    22621 tcattgtatt ctgagctaaa ccagcgttca ggcgaaatca tatggtgttt gataaaaaac
    22681 tttgtctaca tgacttcctt ttgccatttg cttaataccg ttgcattaaa cagctcttct
    22741 ctttggaaat ctcaccaaca tcgcgttcag gagtatcgtt gtggttgcaa tggcaagcgg
    22801 tagcctttca tcaattcttg aatgatttac cgaatgtagc acttgccttc tcgcggtacc
    22861 cgaacccgaa ataaaatttt agtttggcga taaaatcggt atccgccatc gatacttcat
    22921 attttttcgt atcagattca tcggaaactt ccacattgac gaaccaataa gctttggcat
    22981 gcttaggtcg ttttaaacca caccagggcg actaatcgcc ctggtgttca ctttttttta
    23041 ttttacttga actcattgac tgttttccct ttattttaaa cattataaag accgatgagt
    23101 gcttgccgcg tcttttgttt ttatcacggt tttttgtgca aaaaaacctg ccgatagttg
    23161 gcaggtcgtc tacgtgttaa gctttggtgt ggtctttagc tggcaattgg ttttctaaat
    23221 cagttcggac aacaagcaca tcgcaagctg cgtttctaat aacatattca gaaacagaac
    23281 caataaataa acgttctaca gcattcaatc ctgtggctcc taacataatc aaatctactt
    23341 gattatcttc tgggatttct ctggcaataa tttgttttgg tgagccatat tctacgacag
    23401 aggttacatt attcaagcca gctttcttcg cattgctttc ataatctgcc aatgtttgct
    23461 ttgccatttc agtagcttgt tctgcaagca ttccatcaaa ggatgaaacg gtttggaaag
    23521 aacgtgtgtc aatgacatgt gctaatagaa gttctccgtt atttcggata gctacattga
    23581 ccgccttttt aaaagctaat tcagcttcat cagaaccatc tacggcaacc atgatttttt
    23641 tgtattgttg taacataagc attcactcct caagtcaatc gtattgtact cttttattgt
    23701 agaacacttt agggaaaaag agaattattt actgctttgg ttcagcaatt ttttttgcaa
    23761 atcggatact gaaggtggca gaaacaataa ttacgatcag taaaaagacc aaggcaataa
    23821 agcgttgatt gaaaaaagct gttaaaatac ccattacgcc taaaacagca tatgcagctc
    23881 cgtaaaattg taggaatcct tgatttttat catttttgtt gatcaataca aaaaagatat
    23941 cctgtttatt aaataaataa tagctaacga ataataatac taaagtggcg ataatcatta
    24001 aaatcctaat catgaacaaa tcctccaaaa taagcaacaa atagaaaaag caatttgcca
    24061 agagcaaatt gctttattct ttaaaagatg gtaatctccg ttaatgccgt tgtttgtcct
    24121 gtagtattga tcccgcgaat tcaagcaggt gggtcccatg gtcgtagctt cgaactacca
    24181 aatgataagg catgttacca gcagtgacac aagacgggtc ccaagatatc aataaaaatg
    24241 ttcggtcaac acacaaagag gacaattcga acatcacaga tttcccacct ctatagtagc
    24301 atatgaattt aaaaagagca atgagagagc tcgcagaaac agaaccgttt tcttgtctag
    24361 ttttttggag gatgcttttt ccactctttt atacggtaat actgttgacc cagagcctgt
    24421 tcatatttcc ctgtatcttt tggctgataa tactgagcat tcttcagttt atctggtaaa
    24481 tattgctgat tgacccaagc ctgatcaaaa tgatgaggat actgataacc cacgccacgg
    24541 ttgagtgatt tcgcaccttt gtaatggcta tctctcaaat gatcaggaac atctccagct
    24601 ttgccctctc gaatatcagc aagtgctgca tctaatgcca tgtaggcaga attggatttt
    24661 ggcgacaagc aaagatcgac gacgacgtct gctagtggga tacgtgcctc aggcaatccc
    24721 aatttttcag cagctaatac agcgttcact gtacgagccg cagcagcagg attacctaaa
    24781 cctatatctt cataaccgat aaccatcaga cgccggcaaa tacttgccag atcacctgcc
    24841 tcaactaaac gggcgagata atgaagtgca gcatccacat cacttccacg aatcgatttt
    24901 tgaaaagccg aaataacgtc ataatgagca tctccatttt tgtcatgggt aagagctttt
    24961 ctttggacac attcttcaat gatcgacagt gtaagatgaa tccttccttc tttatctgaa
    25021 ggagtcgata gtgtagccag ttccagccca ttcaatgcac tccgcaaatc gccgttcgtt
    25081 gcacgcgaaa ggtgaagaag agcatcttcg tctaactgga ttgcttgttg tccaaggccg
    25141 cgttctttat cccttaaagc atgttcgact gccaactgga tgtcttgttc tgttaatggt
    25201 ttgacttcaa agatctgtgt acggctgcgg atcgctggat tgatggtaat ataaggattc
    25261 tcagtagtcg ctccgatcaa gatgattcgg ccactttcta aatgaggaag cagaaaatcc
    25321 tgttttgttt tatctaatcg gtgtacttca tccaataaga ggatcactgt accactcatt
    25381 tttgcttctt ccgctacaac ttgtagatcc ttttttgaat ctgtagcggc gtttagcatg
    25441 cgaaatgcat aattagtaga gccggcgatc gcacttgcga tactcgtttt tccagtacca
    25501 ggaggtccat atagaatcat ggaagagagc atgcgagcat cgaccatgcg gcgtatgatt
    25561 tttccttccc cgactagatg ctgctgacca acgacttcat cgatcgttcg aggtctcatg
    25621 cgataagcca atggctgttg cataggattt tcctccttct tgtttttacg tcccttaatt
    25681 atatcatatt tagcaagatg cctagaaaga acagccttct gttgttttgt tttcatagct
    25741 tatccaacta atattgtgta tgataaagta ggtgagaaaa atgacggata aacaaaagat
    25801 agatgaattt ttttggaata aaacgacgcc agaagtggca cgggatttat tggggatgta
    25861 tttggagcat gacacaccag aaggaagatt agctggatat attgtagacg cggaagcata
    25921 cctaggtcca gaagacgagg ccgcccatag ctatggttta agaagaacac cgcgtgtgcg
    25981 ggcaatgtat gaaaaaccag gtacgatcta cctttacacg atgcatactc atcggatttt
    26041 gaacatcatt actcagccag aagggattcc tcaaggagta atgatacgtg caatcgaacc
    26101 cgccgcaatg attgatcaaa tgagtaaaaa tcgtggcgga aaaactggtc cagatatcag
    26161 caacggtccg ggaaaattag tggaagcatt agcaattcct caagaacttt atggtcagtc
    26221 tatagcagat agttcgttac gcttagtttt tgagaaaaaa aagacaccaa aaaagatcaa
    26281 tgctttgcct agaatcggta tcccaaacaa aggtgtatgg acagaaaagc cgttgcgttt
    26341 tgttgtgtcg ggaaatcctt atatctcttt acaaagaaaa aaccaaatcg agaaagattg
    26401 gggttggagg aaagaaaatg aaaaagaagg atctattaac atatttagat gaaataattg
    26461 aaaaacaagt gacagactat gatgtagctt tagattggga tacaaaaaat catacgatcg
    26521 agatcgttgt tcgcttgttt gcagaaaata aagcacaatt tgagattgat gatgcagaag
    26581 ggatcgtttc gcaagaacca attatcgaat ttgaagacgg cgtacttctt tttaatcctc
    26641 agaaatctgt ttttgatgaa cgcaattatc tagcagtaat cccttatgaa ggaaaaaaag
    26701 ggttggcaaa atcagtagct gattctttag tggaatatct aaatgaagta ttagctcaag
    26761 ggcaaagcga tttgcttgat tttttggatg aagacgatga cgaagctgta ttcgagcttc
    26821 actgggataa tcagcaacta gcagaattag tagaagtaaa acagcaaaat gaagcagata
    26881 cttatttacc gtacccaagt tattaaggag tgacagatat gaaatggaat gaagtaaaag
    26941 tagaaactga aagtgaagca gtcgaagcag ttgctaatat tttgatggag gcaggggcga
    27001 gtggtgtcgc gattgaagat tctttagatg ttgaacattt tcagtcggat caatatggtg
    27061 agattttaga taaaaatgat tttacatcgc tgaaagaagg cgcactagtc atggcttatt
    27121 ttccggaaac gactttctta ccggaaatct tgccttttat caaagatcgt atcacacaat
    27181 tacctgagtt tggtctagct attggaaaaa ataaagtaac agttagtgaa gtagaggaaa
    27241 gcaactgggc aacagcctgg aagaaatact atcatccggt gcgtattacg cgaatgctga
    27301 cggttgcgcc aagctgggaa aactaccaga cagaagatcc tctagaaaaa attatcacac
    27361 tagatcctgg tatggcattt ggcacaggca ctcatcccac gacttccttg acattgacag
    27421 cactagaaac agtcttgcgt ggtggtgaaa cattgctaga tgtgggaact gggtcgggcg
    27481 tgctaagtat tgcagcaaaa tatcttggtg caaaagatgt ctatgccttt gatttagacg
    27541 aagtagccgt tcgttcggcg aaagaaaata tggatatgaa tgaaatagcc aaagatgtcc
    27601 atgtatcagc taacgatctt ttgacaggaa tcgagattga aagtgatgta atcgttgcga
    27661 acattttagc agatatcatc ttattgatga tcccagatgc ttggcgttta ctgaagcaaa
    27721 caggcacgct gatcgtttca ggaatcattg aagagaagaa gcaaatggtt ctggatgcca
    27781 tgttagaaca agggtttatc gtggatcaaa ttttccagca aaaagactgg tatgcaatta
    27841 ttttgaaaaa accagaggtg gaatagatgc agcggtattt tttaaaagaa tcatatgaat
    27901 caaaagacta ttttgtttta gaaggggaaa actatcacca cattgtacgg gttatgagga
    27961 tggaacccga ggatgaagtt tttttggcat tcaatgatca aatagccatt gttgcagaaa
    28021 tcacggagat tactgaagag gctgtttatc tgaaagaaat taaaaaagaa gaaaatcaaa
    28081 aggaactgcc aagttcgatt accatagcga gtggctatcc taaaggggaa aagctggatt
    28141 ggatcgttca gaaatccact gaattaggag cgcaagcttt tcttggtttc ccggcatcag
    28201 cctctgtcgt taaatgggat gcaaaaaaac gtatgaaacg acaacaacgg cttgaaaaga
    28261 ttgctcaaga ggcagcggaa caatcccatc ggcagatcgt gccatcagta gagttattgg
    28321 aaacgaaaca agatttattt gagcggctag atgattatga cgtggtcttg gttgcttatg
    28381 aggaatcagc aaagcaaggc gaaaaatcaa atgcagccaa aattcttagt gaaacaaaac
    28441 cagatagtcg aatcttagct gtctttggac cagaaggtgg attatcccgc gatgaagtcg
    28501 attattttgt agaacacaaa gggatacttt gtggattagg accaagaatc cttcgtacag
    28561 aaacagcacc tctttattta ttaagtgctg ctagctatca atgggaatta atgaatcctt
    28621 ctttcagcta acgttcttca ttaataaaag agtatcgaca gaaagaattg aaaaaatagt
    28681 caacaatttg tataatagaa acaattattt atacaatgga tacgaaaaat cgtttgaaaa
    28741 agcttttaaa aagcgaacat ttccgtaaaa aaacgtataa ctgcacggat tttgggacaa
    28801 ttatcaaaca gatatttgtc ccgattcccg ttttaccgaa aaaagaaagg gggatcgatt
    28861 cctgtgacaa aagaagaaat tttaacggga cccggtgtca taaagctcgt tagtcaatac
    28921 atgggtcccg aacatgtagc atttgttgag aaagcatgcg aatacgcgac tgctgcacat
    28981 gacggacagt ttagaaaatc aggcgaaccc tacattattc atcctatcca agtcgcaggt
    29041 atattagcag atttaaaaat ggatccccat acagtggcta caggcttctt acatgatgtt
    29101 gttgaagata cagaaatcac tttagaagat ctgagagaag aatttggcga tgacgttgct
    29161 atgttagtgg acggcgtaac caaattaggg aaaataaaat ataaatccca cgaagagcag
    29221 ctagcagaaa accaccgaaa gatgctgcta gcaatggctc aagatttacg agttatcatg
    29281 gtcaaattag ctgatagact acataacatg cgtacgttga agcacctgcg agaagataag
    29341 caaagaagga tcgctcagga aactttagaa atctatgcgc ctcttgcaca tcgtctaggg
    29401 atcagccgga tcaaatggga attagaagat acagcacttc gttatctaaa tccaaaacag
    29461 tattaccgta tcgtccactt gatgcagacg aagagagaag aacgtgaaaa atacgtaagt
    29521 ggtactgttg aagatattcg aatagcgaca gaagagctgg ggatttttgc agaaatctat
    29581 ggacggccaa aacacattta ttcaatctat cgtaaaatga aagatcagaa aaagcagttc
    29641 aacgaaattt atgacttgct agctattcga gtgatcgtag attcaatcaa ggattgttat
    29701 gctgtattag gagcaatcca cacaaaatgg aaaccaatgc ccggcagatt taaggattat
    29761 attgccatgc caaaagctaa tatgtaccaa tctttgcata ctaccgtgat cggtccggca
    29821 ggaaatccgg tagaaattca aatccgaaca caggaaatgc atgaaatcgc tgaattcggg
    29881 gttgctgcac actgggccta taaagaagga aaaaatgaaa aagtagaacc agatggtatg
    29941 acgaaacaat taagctggtt ccatgagata ctcgaacttc aagacgaaag ctatgatgct
    30001 tctgaattta tggaaggcgt aaaaggagat atctttagtg ataaagtcta cgtcttcaca
    30061 ccaaaaggag acgttactga gttaccaaaa ggatccggac cattggactt tgcatacagt
    30121 atccatacag atatcggtaa caaaaccact ggtgcaaaag taaatggcaa aatggtgcag
    30181 cttgattaca aattgaaaaa cggagatatc attgagatca tgacttctcc aaattcattt
    30241 ggcccaagtc gcgactggtt gaaattagtt gctactagca aagcaagaaa taagatcaaa
    30301 cgtttcttca aagcccaaga tcgagaagaa aatgtgatca aaggccacga atccgtggtc
    30361 aaatgtatta cagatctagg atttacgcct aaagatattt tgacgaagaa caaactgcaa
    30421 gaagcactcg atcgttttaa ttatcaaaca gaagatgatc tctatgcagc tgtagggtat
    30481 ggagaagtta gccccttgac gatggccaat cgtctgactg aaaaagaacg taaagaacaa
    30541 aaaatcgagc agcaaaagca agaagcagaa gaaatcatga atcagccgaa aaaagaacct
    30601 gacaaaatga aagtacgtca tgaaggtggc gttgtcattc aaggggtaga aaacttacta
    30661 attcgtatca gtcgctgctg taatccgatt cctggtgatg atatcgttgg ttatatcact
    30721 aaaggcagag ggatatccat tcatcgtcga gattgtccga atgttcagcc tgacaaacca
    30781 aatgtagcag aacgtttgat tgaagtcgaa tgggaagata catcgaatac acgaaaagag
    30841 tatgatgcag atttggaaat ttacggctat aatcgttcag gcttattgaa tgatgtactt
    30901 caaacagtca atgcgctaac gaaaaatctc aacagcgttg aagcacggac gaataaagat
    30961 aaaatggcga cgatccattt gacggttggt atccagaatt tatcccacct aaagagtatc
    31021 gtggataaaa tcaaagcagt acctgatgtc tacagtgtac gccggacgaa tggataggag
    31081 gacagatatg agagcagttg ttcaacgggt aagtaaagct gctgtgtcag tcgatcagca
    31141 agaaattgga aaaattggct acggcctact tgttttatta ggcattcatg aaaccgatac
    31201 gcaaaaagat gtggactatc tggtaaaaaa aattgcacaa atgcgtattt ttgaagatga
    31261 acaaggaaaa atgaatatta gtgtagaaga tgtgggagga caaattttaa gtatctctca
    31321 attcacactg tttgcggata cgaaaaaagg aaatcgacca agctttgtgg aagccgcacg
    31381 accagaaaca gctattcctt tatacgaatc attcaatgaa ggaatcagaa gtcgcggcat
    31441 cacagtcgct accggacaat tcggagcaga tatgtcggtt tctctcgtca atgatggacc
    31501 tgtaacgatc attattgatt ctaaaaacaa ataaagtaat ctggttttca ctagtaaaaa
    31561 ctatgaaaca cgtcgcttaa gttagactga taaactctaa cttaagtggc ttttttgtct
    31621 gcaaaaagcg cttcttttgt cagcagtcgg aaaaaaagtt aagcttaaat tatacaagtt
    31681 attttttata ggaggttgct gaagatgaaa gaagtaccag tagtagatat caaaatcaca
    31741 gatttaaaaa aattgtatca aaaaggatac aacatgttgg aggagttacg ccatgaagcg
    31801 gacgctcccg tcgtcaaagc aaagattttc aataaagaag ctatcacgat ctacggatca
    31861 tcagcagcaa aagtatttta tgatccaagg aatttcaaac gaaaaggtgc tatgccaaaa
    31921 ttagtattga agacactttt tggtcaaggt ggagtacaga ctttggatgg agctgctcat
    31981 caccatcgga aaaatatttt tatggatcta atgacaccgg aaagaatgga agattatcat
    32041 cgtatcttag ataagaatct gacacaagca cttgaagcac agcatggtca atttgaacta
    32101 tttgatttaa gtaagatggt tttctttaca tctatttgcg agtgggcagg tatcaattta
    32161 tcagcgattt ctaaagatga ggtcgaaaaa ttagcagaat atcaaatctc tatgatcagc
    32221 ggaacgttta cttctccgat tgatcacata aaaggtgtcg aaaatcgcaa aaaatcagaa
    32281 aaatgggcgc aaggcttgat tgaagaagct cgacaaaatc ctgtggctgg aaaagaaaat
    32341 gtggcattat atgcttttgc caatgccaca gatttagatg gtcagctttt acctctggaa
    32401 gtggcagctg ttgaattatt gaacatcatc cgtccaacgg ttgctctaac tgtgtgggcg
    32461 gcattgatgg gacatgcact tttcagtaga ccagatttgt atcagcaatt aaaaaatgac
    32521 ttttcgacgt tacaagatcc gtttattcaa gaaatgagac gctattatcc tttcttccca
    32581 atgctacctg cgatttcgct gaaagaagta gaagtagatg gttatcgtat accagaaggc
    32641 agttgggtta ttttagattt atatggaaca gaccatgatg aacgaacagt tgaagcgcca
    32701 gattccttta tgatcaaacg gtatgtaggg aaagcaaaag atatttccta taaagaagaa
    32761 tatgagatga ttgcacaagg cgggggaaat tttcgacaaa tgcatcgctg tgcaggagaa
    32821 tggatcactc ttcatagtct acgtgtgttt tccgatcagc tagtaaataa gtttgagttc
    32881 tctgtacctg aacaagattg gacgattcca ttcaatcagt ttccgactta tccgaatagc
    32941 cgagcgctac tttacaagaa ttagattagc ataaacttat cgaaaaaaag gaagatcaaa
    33001 cagtgctgat cttccttttt tcatattact ataaattgat aaggtcaatt gatcaaaatc
    33061 cacgaaatgc ttcatcaatg gtttgataat cttcattgga taaatgcaaa tctaaagctt
    33121 ggacattgtc agatacttgc tctggacgct tagctccagg tataactaca gacactcgtg
    33181 gattcttcat gtaccaagct aaaacaagtt gcgcaggagt ggcttggtat cttttagcaa
    33241 tggggcgaag tacatcgaca gcggttaaaa tttctctgaa acgttctcct tggaaatctg
    33301 gatttctttt tcgaggatct ccttcaccaa attgtttttc ctcaccaagt tcatattttc
    33361 ctgtcagcaa accggaagca agaggaaaat agggaacaaa actgattttg tttttttcaa
    33421 gataagggaa taattctttt tcagcctgcc gatggatcaa actgtattta tcttctacta
    33481 catcgacata tccatctgca ttcgcttctt tcaattgttc taacgtgaag tttgacacac
    33541 cgactgctcg gatttttcct gcttctttta attcgtgcaa tgtagcaact gattcatttt
    33601 ttggtgtgct ttcatccgga aagtggatat aaaaaatgtc gatgtaatca gtttgcagac
    33661 gttttagtgc atcttccacc gattgtttga gaaactcagg agaattatca aatgttcgcc
    33721 ctttatttgg tacatgagca gcttttgtag cgatgacgac acgtgagcga tcatattctt
    33781 tttccttcag tacctcgcca atcagttctt cggaacggcc gtttccgtaa gcataagcgg
    33841 tatcgatcaa attgatcccg ctattcaaag ctgtacgaac tacttgtttt cctgtctcat
    33901 cttccaaacc gtcaaaaaga ttatgtcctc caacggcatt tgctcctaat ccaagctgtt
    33961 ctgcgtagac ttgtgaatgt ccgattctta tttctgccat agctgattcc tcctttttgt
    34021 ctagtctaaa acaaaatacc aaaaagctga actaaaacgt ttttgtgagg ggaaatagtc
    34081 agatatctct tgactttgag actggttttt agtaggttat aagtaatatc gaatgtcaat
    34141 gaaagagcga gtaagttttt gaaactttac aagagaggat catcgaggct gaaaatgatc
    34201 taaagtttca ttagcctaaa gacactctgg agatggacga gtgaaaagcc gtcccgcgta
    34261 cgagcgttat tcgtaagagg aaagagaaat ctttcaaaat taggtggtac cgtgtatgaa
    34321 tttcattcac ccttgttcat gatgaacaag ggtgattttt ttatttacat agctaagaaa
    34381 gggagagaaa actatgagtt tccaaagacc aaaaggaaca aatgatattt tgccaggcga
    34441 atcagaaaaa tggcagtttg tcgaagaaac agcacgttta ttattcagag attatcagta
    34501 taatgaaatg cgtacaccga tttttgaaca ctatgaagtg atatcccgaa gtgtagggga
    34561 tacaacggat atcgtttcaa aagagatgta tgatttttat gacaaagggg aacgccatgt
    34621 gacgcttcga ccagaaggta cagcaccaat cgttcgttct tttgttgagc ataaattgtt
    34681 cggcccagag tatgcgaaac cgttcaaaac tttttatatg ggaccaatgt ttcgctacga
    34741 acgccctcaa aaaggacggt tacgtcaatt ccatcaaatc ggagtagaag catttggatc
    34801 agaaaaccct gcaactgatg tggagagcat ggtgatggca cttgatttct tcaaacagtt
    34861 ggggatcacg caaatccggc tagtcatcaa ttcattaggt gataaagaaa cgcgtcaagc
    34921 ctatcgtcaa gcattgatcg actatctttt accttttgaa tcagagctga gtgaagactc
    34981 taaacgccgc cttcatgaaa atccattacg cgtattggac agtaaagaca aacgagatca
    35041 aaaatttgtg gcagaagctc catctatctt agattatcta agcgagcctg ctcaaaaaca
    35101 ttttgatacc gttgtttcca tgctggatgc attggctgtt ccttatgaaa tcgacagtaa
    35161 tatggttcgc ggactagatt attacacaca tacgattttt gaaatcatga gtgacgcacc
    35221 aaaaatgggg gcacaagcaa cgatttgcgc aggcggacgt tatgacaatc tagtggaaga
    35281 actaggtggt ccttcaacac ctggcttcgg atttgcaatg ggtatcgagc gattactctt
    35341 gactatggag gcagaggaag tagttatccc tgcatttaat gagttggatg cttacgtggt
    35401 cgcactcgga gacgaaacaa atatcgaagc attgaaagtg gtccaagcga ttcgaaactt
    35461 tggtttttca gctgaccgcg acttcatgaa ccgtaaagca aaagcgcaat ttaagacagc
    35521 agataaagcg aatgccaaat tagtattggt gatcggtgaa gatgagcttg ctagtcaaac
    35581 gattaatgtc aaagcaatgg caagccgaaa agaaaaaagt tttccattag aagagatata
    35641 tgaacatttt gatgaagtct atgatgaaat gactttattc gagtaggagg aaaaaaataa
    35701 atggcacaaa gaacgatcta ttgcggatta gtttccgaac aacaattaga acaaacagtt
    35761 acattaaaag gatgggtaca aaaaagacga gaccttgggg gagtaatctt tatcgaccta
    35821 cgtgatcgtg aaggaatcgt tcaaatcgtc tttaatcctg aaatcaacaa agaagcatgg
    35881 gaaatcgcgg ataaatgtcg cagtgaatac gtgatcgaag tgactgggga agttagaaga
    35941 cgcggagaaa atgcagtaaa tcctaaaatg gccactggtg aattcgaagt gattgcaagt
    36001 gaaatcgtga ttttgaatca agcaaaaacc ccgccatttc aaattgaaga tgatcaagca
    36061 atcagtgacg aaatacgttt gaaatatcgt tatttggatc tgcgtcgtcc aaaaatgact
    36121 aaaaacatca aattaagaaa tgcgacaaca aaagcgattc gtcattattt agatgataat
    36181 gactttctcg atatcgaaac accttaccta gggaaatcta caccagaagg cgcaagagac
    36241 tacctagttc cttcacgtgt ccatgctgga catttctatg cgttgccgca atctcctcaa
    36301 ttgtttaaac aattgctgat gaatgctgga ttcgaccgtt attatcaaat cgttcgttgt
    36361 ttccgcgatg aagatttacg tggagaccgt cagcctgaat ttacgcaagt agatattgaa
    36421 acaacgttct taacagcaga agaaatccaa acttacacag agggattgat tgcgaaggta
    36481 atgaaagaag ttcgcggtat cgaagtcaca ttgccatttc ctcgtatgac ctatgatgaa
    36541 gcaatggctc gctacggcag cgacaaaccg gatacacgtt ttgatatgga attgatcgat
    36601 ctaagcgata cagtcaaaga agtagaattc aaagtcttcc aaatggctct tgaaaacggc
    36661 ggtgtcgtga aagcattgaa tgctaaaggc gctgcagatc gctactcacg aaaagacatg
    36721 gatcagttag gtcaatatgt aggacaattc ggagctaagg ggcttgcatg gctgaaagta
    36781 gaagaagacg gattgaaagg tccaattgct aaattcatgg gagaagcaac agaagcaatc
    36841 attaaagcaa cagatgcaaa accaggtgac ttgctgatgt ttggcgcaga taaaagtgaa
    36901 atcgtcgctg ctgcattagg tgctatccgg acacgtttag gaaaagaatt aggactaatt
    36961 gatgaatcga aattcaattt cttatgggta actgattggc cacaatttga attttcagaa
    37021 gaagaaggtc gatatgtctc tgctcaccat ccattcacga tgccaaaaga agaagatatc
    37081 ccgttattgg ctgaagaccc tgcaaaagtc tatgcagaag cttatgatat cgtcttgaac
    37141 ggttatgaac taggcggagg ttctatccgt attcatactc gtgagcttca agaaaaagta
    37201 ctagaaactc taggctttac aaaagaacaa atggaagaac aatttggttt cttgttaaca
    37261 gctttagatt acggattccc tccacatggc ggtattgcat taggattgga ccgttttgca
    37321 atgttattag ccggagaaga taatattcgt gaagtcattg cctttcctaa aaacggaaaa
    37381 gcagcagatg tgatgagtga tgcaccaagt atggtttcgc ctttacaatt gttcgaattg
    37441 aatattgatg taacgaatat agaagaatag ccgataaaaa ggtaaaaagg atttgtcgaa
    37501 tacgcttctt ttgacaacct tgatttaatt gaaaaacact ttataatgaa gccataacat
    37561 ataaagcggg gcttttccat gaaaaaaaca ttcgaaaatt gggcttatca tgattacacg
    37621 accaagcttt cggtatctat cgtttatgcg ttgatcgcat cagtcgcatt gaatttcttt
    37681 tatcagccag gacatattta ttcaagtggt attactggtc tagctcagat tttgacgact
    37741 ttgtcaaaat cactgatagg attcgaagta ccggtatcaa caactttgta tttactgaat
    37801 atacctttgt ttgtattggc gtggttaaaa atcgggaaga agtttacaat tttcactttt
    37861 atcacagtca ctttgacctc cctttgtatc catattttac cggaaacagt cctatctacc
    37921 gatccaatca tctgtgcgtt gtttgggggg gctgtgatgg gactaggtat tgggctagcg
    37981 ttgagaaacg gcctatcatc gggcggtcta gatatcgtga gtatcacgat tcgtaaaaaa
    38041 acaggaaagt cgattggttc tatttcgatc tacttcaatg cattgatcgt ttttgttgcc
    38101 ggaattctat ttggctggca atatatgttt tacagtacgt tgtctatttt cgtcagtgga
    38161 aaagtaactg atgtcgttta tactaaacaa aagaagatgc aggtaatgat cgtaacgaaa
    38221 catccagaaa aagtagtaaa tgaaatccaa aactgtatgc gtagagggat cacgatcatc
    38281 aatgaagcag aaggtgctta taagcatgat aagcagacag tattgatgac gatcgttaca
    38341 cgatacgaac tgcctctact tagagaagca atgaaagctt ctgatccaca agcttttgta
    38401 agtattgcag aaaacgtcca gatacttggt cgtttctatg aggatggcat ttagatcgag
    38461 tttgacaaaa attcatgaaa tactgctgta gacagacgtt cgtttgtctg cagttttttt
    38521 ctaccatagt agaatcagca aagaaaaact gcttttttat ttgaaatttt cttaaagttg
    38581 aaaaaaagca tgtttatttt tttaaattta tgggatgata gaaaaaaata gtagagaaag
    38641 gacacgattc tacttgctat tttcacttaa tacccgtata ttacgaatga aaaaagttta
    38701 tgaaaagttg gaatattgaa tggaaaaaca aaaaaggtta aaaaacagcc gctacatcac
    38761 tgggtttgat gggctccgtt cattagctgt ggtgggtgtt atcttctatc accttctgcc
    38821 aactagtatg aaaggcggct atttgggcgt tccgattttt ttcgtcgtat ctggttattt
    38881 gatcacggat ctgctgcggc aggaatggga acaaaatgga aaaatcaata tttggcaatt
    38941 ttatgtcaga agaatgaaga gactctatcc ggcacttgtt tttatgcttg tgacagcttc
    39001 ggcttatatc actttgtttc agcgagggct gttaaacaat cttcgaggag ttgtggtcag
    39061 cagcttactg tatgtcaaca actggtggca aatcaataac ggtttatctt atttcgatcg
    39121 atttgctaat gagtcaccgt ttacgcatat ctggtcttta gcagtagaag gtcaaaacta
    39181 tttggtttgg ccgatcttgt ttgtattgtt gatggtattt gttcgtaaaa gaaaatggat
    39241 cttttatact gtgttaggta catccttcct ctccgccatc ttgatgatga tcttgtatac
    39301 accaggaggc gatccaaccc gtgtttatta cggtaccgac actcgtctgt tttctatatg
    39361 gttgggaagt gcgcttgcgt ttgtttggcc aagtacgcgt ttaaagaaaa acatcccgaa
    39421 acaagcgaaa aatattctga atatcgctgg aggaatctcg cttttggcac tgattctttg
    39481 cttcttcttt ttagatgatc attacaattt catctattac ggaggaatgc tcctagtgag
    39541 tctgttatgc gtagtgctag ttgcagtgac agcacacccc ggagcaagtt tgaatcgatg
    39601 gctgacaaat ccagtattta cttggattgg caaacgaagc tatggcattt atctgtatca
    39661 gtttccagtt atgatttttt atgaagcaaa ggtgactgat attgccgatc atgttttgtt
    39721 gcatacttta gtggaaatca cattgattct aatcatcagt gaactttctt atcgatatgt
    39781 ggagcgtccg ctagcacgtt ttgattatgg tcgtacattc caagtgatga aaggatggtt
    39841 cagcaaaccg atcatcagta agagcaaacc atgggttgtt ccaggcacat tacttgtagc
    39901 aattgcactc gttggtttcg ttacggcacc gaaaaacgct gtaacagccg atcaaaaaca
    39961 actgcaggca aaaatcgctg aaagtaaaaa attagcagaa gaaaccagaa acaattcaga
    40021 aaacaccact agttcggttg accaagcgat ccttgataag tacgagttgt ccaaggcaca
    40081 agggaataag gcacaaaaat tagaactaac ggcatttggt gattcagtta tgttggatgc
    40141 tgcaacggat ctacaagaac tttatccaaa agtagtggta gatggagatg tcggacgaca
    40201 attatatgcc agtgtaccgt acattgaaaa attaaaggaa caagatttgt tgaaagacac
    40261 tgttctgatc ggactaggaa cgaatggctc attctcggaa gctcagtttg atagtgtgat
    40321 ggatgcaatc ggtgatcgaa aagtatactg ggtcaatgtc cgagtaccga cgaagcgctg
    40381 gcaaaatgac gtgaatgcga tgcttgaaca gatgacgaaa aaatacgaca atatgacgct
    40441 gattgattgg tacagctaca gtaatgacca tagtgactgg ttttatgatg atcaagtcca
    40501 tccaaatcct gaagggatga cacattacat tcacttagtc agcgaagcct tgctaggagg
    40561 aagttcaagt acgaacagca gtgagacaaa cgtgacagaa tgatagctac aaaaaacttc
    40621 aggcaaaaac atttgttttt gcctgaagtt tttttatatt taccgtgttt ttaacattca
    40681 tatagattca ggaagcaaaa cggttgagtg tgtctgtaaa taacgttctt tttgttttcg
    40741 ggtgagtttt ttgaatgcag cttctgcttt tgttgcttcg cttcttgaag aaaatacttc
    40801 tgcatggatc atcttaacag gtcttctttt ttgaagacga gtatatttag caccagtacc
    40861 attgttatgt tcctctaatc gtctagaaag atcggttgta tatccaccat aaaatgtctg
    40921 atctttacag aataatacgt aaaaataatg ttcatttgcc atagagcatc tcacgaatct
    40981 ctgcagtgta ttctccatcc atattgtaag tgatcaatgg tggagcgact ttgaatccgt
    41041 ctaatttgcc ttctttgatt ccttcaacta acaaaatatt tgcctctttt ccaggttttg
    41101 ggtaaacaaa ttggatcctt ttaggtgcaa ttcgatagtc ttccatgacc tgaatgattt
    41161 ctaagaaccg atcaggacga tggaccatag taaagcgtcc atttgttttt agtagcttac
    41221 ttgaaatatc gatcacttct tctaacgtcg tatgaatctc atgacgggcg attgccaggt
    41281 gtttattagg gttcgtttta tttgttggca gccctttgaa ataaggtgga ttacagacga
    41341 ctaagtcaca agaattatgt cgaacgacag ataagctgtc tttcagatcg atggtgtgga
    41401 cagtcatttg ttcatttaaa tggttaagcg cgatactacg tcttgccatg tctgctagac
    41461 gaggttgaag ttcgatagcg tcgatagccg cctgggttcg tttacttaaa aaaagtccaa
    41521 ctgcgccatt tcctgcacaa aggtcaacaa tcttcccttt tttaggtaca cgggaaaagt
    41581 gagcaagcag cacagcatct aaagaaaaag aaaacacttt ggaactttgg ataatcttga
    41641 tatcttctgc gtataattgg tcgattcgtt cgtcttcgtg aagcatggat tccctccaaa
    41701 atgaaaaaaa tagtcgtctg tattatacta tttttattaa aaagaaccaa ggtggcttgt
    41761 caaacctcta ttttttatgc atactatgac cataagaagg gaaaggaaga gactatgttt
    41821 tatcgattta tgcgcggggt agttcgagta ctattagcct tagttaatgg aaatgcccgc
    41881 tatgagaata aagaagtttt accgcaagat gagaattaca tactagttgc tccccatcgt
    41941 acttggtggg acccattata tctggcggta gctgcagcac ccaaggaatt cagctttatg
    42001 gcaaaagaag aactgttcaa aaatccagtt ctgcgattta tattaactcg atccaatgct
    42061 tttccagtta aaagagaaaa tccaggacca agcgtcatta aaacacctgt aaagattttg
    42121 aaatcgacaa atttgagttt gatcatgttt cccagtggga caagacatgc tacagaactt
    42181 aaaggcggaa tggcattgat ttccagaatg tctaaagcga aaatcgtgcc agctgtatat
    42241 caaggtccgt tgacacttgg ggatctgttc aagcgtcaga gagtgacagt gcgtttcggc
    42301 gaaccaatcg acttatcaga tatcaagaaa acggataaag aaggtatggc ggagatcgaa
    42361 cgacgaacac aagcagcttt tgacaaattg gacaaagaag tgaaccctga tttcaaatat
    42421 gaagtcaaaa aaaaataaaa tgataagttt atgcgtgggc ggtcttttga atctactgtc
    42481 ctgttcagtt cagacttttt caatgaaaac gagggagaga cgtcaagtct gccctctttt
    42541 tgcgttccaa tatgtaaaat agaagacagg tgtcatgtaa tggatcaaag tgttataata
    42601 attagaagga cattttttga ggtgattgaa tgcgtttttt acatacagcc gattggcata
    42661 tcggaaaaaa actacaaggt tatgacttga ttgaagacca gcgtcatgta ctatcttcta
    42721 tactagatat cgcgaaagaa gaaaaagtag aggcaatcgt gattgccgga gacttatatg
    42781 ataggagtgt cccagctgtt gatgccgtag aattatacaa tgaattgatg gtcgattgga
    42841 atttaaagga aaagatcccg atttttgcta tatcaggaaa tcacgatagc agtacgagac
    42901 tttcagcggg tacgccatgg ttcagttatt cgaactattt tttgcgaaca cagctagcag
    42961 aagcatttga accagtcgag tttaaaaacg tacaattttt ctttcttcct tactttgaac
    43021 caattgcagc gagattatat tttgaagatg acaatatccg aacgatcaag caagcggtag
    43081 ccaaggtgat agataaaatg caggagctat ttgattcaga aaaaaaacaa gtattgatta
    43141 gccatttttt tgtaatggga agtgtaaaat ctgattcgga aacgaaaatc gaagtaggcg
    43201 ggttggattc gatccctggt gaactactta caccgtttga ttatgtagca ctaggacatt
    43261 tgcataatca agctgctttg agacaggata atgctcgcta tagcggttcc ccattgaaat
    43321 tctctttatc tgagatcaac caaaaaaaag gcgtatggat cgttgacctg acaacaggcc
    43381 tggagttgaa ttttagggag atcgaacccc tgcatgatat tgaagaaata acagcgagtt
    43441 tcaaagaatt gctggatcct gccttttatc agtccgtcaa tcgggagaat tacatctata
    43501 tctatctcac tgatagaacg atcatcccga atatgatgaa ccagcttcgg caaatatatc
    43561 ctcgtatttt ggggattgaa cgggcaaacg gtcgagcaga acaaacaaag cgcaaacgaa
    43621 aagtactaga aatgaaagat cctcaaaaat tagcagaagc attttttagt gaaatgacgg
    43681 aagagcagct aactgcaaac caagaaaaat ggctcggaga aacgttgcaa gaaatcatgg
    43741 aaatggaatg atcaagaatg aaaccgaaaa aattacaact taaaaatttt ggtcctttta
    43801 tcaatgagac cgtagatttt tcacgtttga cagaagcacc gctttttttg atcagcggga
    43861 agacaggagc tggcaaaacg acgatttttg atgggatcac cttcgcactt tttggtgaaa
    43921 cttccggaag acttcgctct ggaaaagaga tgcgttcttt gtttgctaca ccagacgaag
    43981 aaacaagcgt gactttttct tttgaacatc agcagatgag ctatgaaatc gaacgaaaac
    44041 cagaacaagt tttagcaaaa cgaaaaggaa acggaacaaa aaaacaggca gccaaagtaa
    44101 cgttgaccat ttttgatggg aaaggaaaag aaataaaaca aatcacaaaa cgtacagaag
    44161 cagatcagtt gatcagagaa ctgatgaatc tcgatgcgaa acagttttct caaatcgttt
    44221 tactacccca aggagaattc cgtaattttt tggtttcatc aagcagtgat aaagagactg
    44281 ttttacgtca tttattcggt actcaatttt tccaacagtt caatgagcga ttaaaagaaa
    44341 aagcaaaaca acagcaacaa aaattggatc atttagagca agagctgcat cttctgcaaa
    44401 aaaggtttgt tttagtcaaa gaagaggaac cagcagcagg gtttgaagcc gttttagccc
    44461 aatggacaaa ccatcaggca atactcgaaa aacaaatcac ggaagaaaaa gaagctctaa
    44521 cggaacttca ggaaaaacaa aagcaactag aaaattccta ctatcgtttt gaaagcttga
    44581 aaaaaagtta tgaagaaaaa acgatattaa taaacaagca aaaggaatta gctgctcaaa
    44641 aagacgaaat agaggaaaag aaacgatgga ttgggtatta tgaatttacg caacgattag
    44701 tcgaaccaat ccagcgccta caagaaataa aagttgaaaa aatagaactg tcacaaaaaa
    44761 gtagtgagca aacaaagaaa ctagcgatga ctacgcagaa ttatgaagag tggcaaaaaa
    44821 atgaagcaaa ccgcgtacgc cgacaaacaa aaatcaaaga agctgctcaa aaactgcaaa
    44881 acaaacagat gatggtgcca attgtcgaat ccttacgtag taaaaaacaa gacgcagaac
    44941 aattaacaat ttcattggat aaagaagaat tgaatgccga gaagctgtat caaaatctcg
    45001 ctatctatca ggaaagaact cgaattcttc aagaaaattt actggatcag gaaaaactgc
    45061 aagaagatcg tcttgctttt ggacagttaa aatatctaga tgaaaagcag caagaaatag
    45121 aaaaacaaaa agcaaaagac actgggtcgc tcgcacagat aagagaagaa ctcaaaaaag
    45181 caactgaaga aataacaaaa aatagtcagc tattgaaaga acagacagaa caagcagaac
    45241 agctgaaaag ccaatgggca aagcagcaaa ttgctcgtct tcagcttttt ttgcgtccag
    45301 gggagccatg tcttgtttgt ggatcaacgg aacaccccat acaacaatta aaacacgaac
    45361 agccaaataa ggaagatatc ttaaaagtag aacaacaact ggcagaagct gagtctgctg
    45421 tagaaagaac tcagcaaatc attgccaaaa gtgaagcaca tgaaaataat cttcaacaac
    45481 aattatcaga tttagaacaa aaaatcatgg caacgaatat acaattggct gaacaagaag
    45541 aacacttgca acaggctttg aaaaaggcat ttcctgagat aacagaacaa aaaacaaaaa
    45601 caactcttgt agtaatcgaa caatctttag atagacgaaa aagcaagatg gccaatgcaa
    45661 gaatagagct ggaagaaata agacaacaag cagaaaagct cgaacaacaa ttagctgtct
    45721 acaaacagca gcagacagaa aaaaataatc agctccagca actgcaagga gaaatcaaaa
    45781 gtttagaaca acaattgcaa gatacggata gtaactgttt agaagaggag atacgacgac
    45841 ttgaaaaaca gttagaagaa gactcgaatc aactagctgt tgagcagaaa gcaggagtgc
    45901 aattgttgca agatcttcat acgcttcgga cacagcttga tcttcaacat gaacaaatag
    45961 aaaaaataga tgaaaaaata gaaaaggaac aagaaagaat agctaaaaag ttagaaagcc
    46021 agtcgtattt ttcaacaatt gaagaaatct gtgcatttgc acaacagcaa gcacaatata
    46081 aagaaaacca acgtacagtt acttcttatc atgaagagca attagtgaca gctgaccggc
    46141 tgcgtcaatt agaaaatatc cagctaactg agacattccc agatacagaa gagatcagcc
    46201 aacagttaga agaaataaga cgtatgatcg aaataaagca agaaaagata tacggtttac
    46261 aagaacaaaa aattagtaat caaaaaatct acgatgaatg tctttcgatt tatcacacaa
    46321 gccagacgaa attagatgag cttacgcaat tacagcagct ttcgcaaaca ttcaacggag
    46381 aaaatcctaa gaagactagt ttggaacggt atgtgcttca ggtttatctt caagaagtgt
    46441 tacaagtagc aaatgatcat ctccaacgtt taacgaaaaa tcgttatcaa tttgagctag
    46501 cggataccat tggcagttat cgagggaaaa ccggattaga aatcaatatc tatgatgatc
    46561 aggcaggtat gtctcgaagt gcgcataccc tgtctggcgg tgagagtttt attgcagcac
    46621 tttctttagc attagctctt gccgatgtga tccagacaca agctggtggt gtagcaatcg
    46681 atgcattgtt tattgatgaa ggatttgggt cattagatga agaagctttg gaaatggcaa
    46741 tggaagcttt agaaacgatc gaaagtgaag gaagaatgat cggcatcatt agtcatgtaa
    46801 gagaattgaa agaacgagta ttacaacaaa taagaattga tacagaaggt agcggacaaa
    46861 gcaaaatacg ctatcaactt ggataaaaag ggagattggt aactatgaaa tggagtattc
    46921 cagaaaaagt cattgcacgt ggacgtcaat acttgcaaga aggccgagtg ttatcggttg
    46981 tccctgacca agaagaaaac gtgtggcatg cagaagtctt gggcagtgaa ttgtatatgg
    47041 ttgatttgga tggtacagca aaagagatag attactgcca atgtccctat tgggaggaac
    47101 ataaatattg taagcataca gttgctgtgg aactttattt acggtcgaaa aatctatctc
    47161 gtatcatgaa aaaagaccag ccaatgctag aaccggtaaa agcaacaagt gagggagaaa
    47221 tcattgcaaa aggtttttct cgtctaaaaa cacaaaacaa tcctcaagcg gtgcaacctt
    47281 tgattattga ataccaagta gaaacgattg agactaatca gtatcaccca gagctttcta
    47341 ttttggcact ttacttgcgt atcggttcat tggcatcacc gaaaaaaaca tatatcgtaa
    47401 aaaacatcta tgatttttta caagcttaca cagaaaaaga aacttacact gttaataaac
    47461 agtaccagtt tcgtctagat aaacgggcgt ttcaaaaaga agatcaaaaa atactcacgc
    47521 atcttgcagg aagtgctcag acgcatcaat tattaggtac gaacggctta caagtcaaag
    47581 gaaaactaga taaaagatat ctgcttctcc cagtagaaca agcccgcttc ctgttagagc
    47641 agatgaatca gactacacgt ttgcatctgc agataaatga acaaaacgat caaggaatac
    47701 aattttccga tcaaaacaaa cctttatcat tcaaagtgga aaaatttgga gaagattatt
    47761 tgctgcaagc attgaatgat tttgattttt tctttatgca ttatcagtgg ggagttatcc
    47821 aagggacatt ttattctctg acgaaatatc aacaaacggt ttatcaaact tggaaacaat
    47881 tgattcgccg attggagaaa ccagaagtag tgttcaagaa aaaagaatta ccgtctttgt
    47941 ttaaagagat tatccctctg ctgtcagaga tcggcgacgt agctattgcc cctgcagtag
    48001 aagaggaagt agcagatatc cccgtcgaat ttattttctt tttccgaaaa gcaaaaggaa
    48061 aaatccaagc tcgagtcgat ttcgtctatg gcgaagtcat ctattcgact gacccgaagc
    48121 atgaggtctc gacagaacag gcttttcagg tgttacgtga cacagtagaa gagaaacgag
    48181 tacttgatct attcagaatg tatcgctacc agaaaaatga aactggttat gaacgtccat
    48241 tgccaagcgg ggaagaacta tatgcctttt tccgcacaga actatctgtc ttccgtcagt
    48301 ttggtgaagt cagacttgga agaaaattgc gagagttgta tttagatgcg cataaacatc
    48361 aaccgaaaat cgaagtaacc gagaccggtt catggctcga tattcgattc gatgtgacag
    48421 ggatagagga gcaagaaatc gatcatgtcc tgcaaagctt gctgagaaat gatgcttttt
    48481 atacattaga aaatggtcag gttctttctt ttgattcaga agaatttcaa caaacaagcc
    48541 aagtgttgca acaattacgg gaatcgatac gtacagaaga aggaacgatc catgtaccta
    48601 aaaatcaagg attgatcatt caaaatcaat tggaaaaaag caatgctact tttagtgaat
    48661 cgttccaaac gatggtacaa gatctcattc atccagaaag ataccaggca cagcttccca
    48721 aaggattgaa tgcaacgatg agagattatc aaaagcaagg ttttcgatgg ttgaagatgt
    48781 taggtcatta tcagtttggc ggtattttag ccgatgaaat gggacttggg aaaacactac
    48841 agacaattgc ctttttactt tcggaaaaag aagaacggaa aagcttctct gctttgatcg
    48901 tagcgcctgc gagcttaatt tacaactggc aggcagaggt gagaaaattc gccccttctt
    48961 taagtatcca agtaatcaat gggaataaaa aagaacgtga agaattactg gctaaagaca
    49021 cagatatccg agtgacttct tatgccagct taagacagga tctagctaat tatcagtcgc
    49081 aaaaaattga ttatttgatt cttgatgagg cacaaatggt caaaaatagc agtacgaaaa
    49141 ctgcacaagc attgagagaa ttagctgtac ctcagcggtt tgcactgagt gggacaccaa
    49201 tcgagaataa tttagaagaa ttgtggtcat tgtttgcaac gattatgcca ggatttttcc
    49261 cgactaaaac aaaattcagg gaacttgccg cagaagaaat tgcgcaaatg attcgaccgt
    49321 ttattttacg gcgagataaa caaactgtgt tgaaagactt gccggaaaaa acagagatga
    49381 atctatattc tgcacttaca gaagaacaaa aaactgttta tttagcttac ttgcgtcaaa
    49441 tgcgtgaaga aatcacatca atggattctg aagcattcaa gaaaaaccgg atcgggatac
    49501 ttgctggtct gacaagactg cgacaaattt gctgcgatcc tcgtctgttt attgaagatt
    49561 accaaggcgg ttccggcaag ctcgaacaag taaaagatct actggtagct gccaaagaga
    49621 acaaacgaag agttttgctg ttttctcaat ttacagggat gctgactatc ttgcaagaag
    49681 agttagccga gctagggatc tcgacatttt atttaagagg cagtacgaaa ccacaagatc
    49741 ggttaagtat ggtagacgca tttaatgctg gcgaaaaaga tgtttttctg atttccttaa
    49801 aggctggggg aactggattg aatctcacgg gagcagatac ggtcatcttg tatgaccttt
    49861 ggtggaatcc tgccattgaa gaacaagctg ctggacgtgc acatcggatc ggacaaaaaa
    49921 atgtggtaga agtgtggcgt atgatctctg aaggaacgat tgaggaacgc atggattcac
    49981 tccagcaaga aaaacgcgaa ctgttccaaa aagtgatcca aggtaatgaa gaacagttga
    50041 cgaaactgac tgaagaagac atccgcatga ttttaagtgt aggagaaatc gaggagtaag
    50101 agactcgaaa aagcgttcag taatgggtaa gaaagccttt ctaaagaagc gattgtttat
    50161 ttgatttaaa aaatagcaag gaggctggga ttccatttta tcccagcttc cttgctatca
    50221 tttttttatt tctattttta aaggttatac aaagattgtc ttcattgtct ctaacagctg
    50281 atcaaaagaa gaaatctcga tatcgcaaat tggagtctgt tcaattttgc gttctcgatg
    50341 gttgaaccaa agcgcttgcc agttagcact ttttgcacct agaacatcat tgtcgtaatt
    50401 atcgccaacg tataaggtct cttctggaag catatgaaat tctttctcag ctagctgaaa
    50461 aatctctttt tctggttttt ggaaacctgt tgcttgagaa atgagcatat tgcgggaagg
    50521 aatccaattg ttcaattgaa gttgcttcag tttttttgtc tgatggtcag tcggcccatt
    50581 tgtgataatt cctaatggga cattcttttc cttcaagaaa tcgagggttt ttttgacctc
    50641 ctcatgcaag cagatattat caagttcttc ctcgtaaatt ttttgaaata agaggccatc
    50701 ttcttccgta atatgagggt agtctaaatc ttttagtgat tggctgatcc gatgtgctcg
    50761 catatattct agtgtccaat ctcctgccat tacttttggg aagttttcat cactatgatg
    50821 gcggaaccgg atatatagtg gatgcatatc tgcatctgaa acaagcggaa cgactctttt
    50881 gaccgcgttt cgaaatggct gctgctgatc atacatcgta tcatcaacat caaacacaac
    50941 tgatttaatc aaaattttac acgcctttcg gttttcattg attttttcac aaatccttga
    51001 ctattgtaac agaaaaaatt gtctaaaaaa gctgataaat aaaggttttt cttactatat
    51061 ttctatttcc ttgacagaat aaggttttta tatttcagtt tttttcacta aaaatcgtga
    51121 aacacgtcaa taagtttgat gaacaaatta atcattatgg tagaagtcga ttgatttatt
    51181 ttaatgcaat ctctgtggaa ttttcgaaag atttattttt ttaatacagt ctcaatataa
    51241 ctattcaaac ataaaataac gttatttgat ttatttgttt atagtaaatt ttatttagta
    51301 atcattgctt taaaatacta cgcttatata acagagaaaa taagcgttat aataaagaac
    51361 agtattattt aaaatgacag aaaacattac tattaaagaa ataaaaaaca taaaaaatct
    51421 taagaaatcg gtttcattta gcttttgaga taaaataata gtacagtttt atacgctgtt
    51481 tcatatgttt agaaaatttg aattagattt gaaaactcta atttttaaat gataaaaaaa
    51541 gcgagaatgc tggttttact gtatattaac cttagataac tttcattttt ttaaaaaaat
    51601 tatgaaaaaa aggtagctat ttaaaagttg attatgtata atagaaacag atgggagatt
    51661 attatgatct tctgttacaa aaaagtgatt cttatcacga aaaggagtgg tgcacgttgt
    51721 taacattata tacttcccca agttgtactt cctgcagaaa ggctcgtgcg tggttgcaag
    51781 aacatcagat tccatttgtt gaacgtaata ttttttcaga accattgaac agttctgaat
    51841 taaaagcgat tttacaaatg acagaagacg gaacagaaga aatcatctcg acacgttcca
    51901 aagtattcca aaaactgaac atggatttag atgatctgcc gttacaagaa ttattggaac
    51961 ttgtgcaaaa caatcctgga ttgcttcgcc gtccaatcat gattgatgat aaacgtctgc
    52021 aagttggttt taatgaagat gaaattcgtc ggttcctacc gcgcgatgta cgacaattag
    52081 aattacgtca agcacaattg atggctggat tatagaagga taatacgaaa cttggaaaag
    52141 actattacaa agatagtttt tccaagtttt tttgttttta caaaaagtat tcttgattag
    52201 atgtataaaa aggtagtaga agatgatgat tgcacgaaaa atagagaggg aaaattagct
    52261 gaaaagtcgg ctatatagta ttcgtctgcc aaaaatgtta tagttaaata agatagcttg
    52321 aaaggttgaa aaatccgctg gttttattaa attcgcttaa cagcgagatt ttttttcttt
    52381 acatttaagc tgatttcgct acaatgaatc tatattaaac attgtggcaa agtgaggtgt
    52441 agcaaaatgg aaatggaaca tattaatgaa aatacgatcc gtgtactaat tggtcatgaa
    52501 gatttagagg aacggggcgt ttcatttttg gatttacttg gcaatcacaa agaaatcgaa
    52561 aatttctttt atagtatttt ggaagaagtt gatatcgaag aggagttccg aggaagcgaa
    52621 gctgtcactt tccaagtttt gccaaaagga gacggattag aactgtttat cagtaaaaat
    52681 cttccggatg aagaaatttc tcaatcagaa gattctactg ttgattcaga agatgtgagt
    52741 gactttcttc gtcagcagat tattggcagc gatccggagg aagaattatc tggaagcgcc
    52801 ctagaagaac aggaaagaca agcaactttt gcttttgaag attttgaaca agtgatccaa
    52861 cttgcaacag atgtcgaact agagtctgct tggactgatt tgtatttatt cgaagagcgc
    52921 tattacctag tcgttcactt ctggatggaa aatctcaacc aagcggatgt agagaatcag
    52981 attgctcgaa ttttggagtt tgctgaaaag agcgatcgta caccagaaac attgaatgaa
    53041 tatggacaat gtctgatggc gcgtaatgct atcgagcgaa cgaaatttta ttttgtataa
    53101 atcagcatta tagtaagaga ctgtgacaaa aattgtgtcg cagtcttttt ttcgtataaa
    53161 tgtgttcaaa agcttgcatc tgcggtaaca agcccaacca aacgaaaaat attgggaact
    53221 atttttgttt agctgttctt attacttgat gcagaatagc tttttcacgc cctctttttt
    53281 cgtgtaaata aattcttaga cgtaaataag ttcagaggga gaaaaatgct gcttgcaatg
    53341 aatgaatata ataagtgctg ttttgctaaa catgcagaaa aaggaaagaa atattattgt
    53401 cgtggctgtc gaaaaagagt gattttgaaa aagggaaaga aaaaatgtgc tcattttgcc
    53461 catcaaaaat cagataactg ttcggtcttt agtgaaagag aatcaaaaga gcacttacag
    53521 ttaaaggaat gcttcatgga ttggctggga cagtcagtag aaccagtatt tttggaagcc
    53581 tatttgccga ggttgcggca aaggccggat attttgttgg cgaatctagc aatagaaatc
    53641 caatgttcta gactgtctca ccagagattt attgaaagaa cccaaaatta tttgaataac
    53701 agttaccaag tatggtggat acttggtaat tcttttcttg gacaatcgca attctcattg
    53761 atagaaaaaa gttgctgcta ctataataga aaaagaggag tgcattgctg gaaagctgat
    53821 ctcaagaaac aaaagcttta tttgtatcat catattacag agactgtatc agggcatatt
    53881 tccttttgca gtagctgctg gactttttct agtagggacc ttaaagaaat attcactagt
    53941 aacgaaatta aaatgaacca aatgaaaaaa atagaaaaag tgagtgaaga tgggaagaaa
    54001 tggctgacac gccaacttat tcacaagcaa aagaatacag tatccataca agaacaatgc
    54061 tacttgcgtc ataaacatct tttgcatcta tcatcgtgga tctatcaaaa aagtcggttt
    54121 ttcttttatt tacaagaaca ggtttttctt tatcgaatgt tgtacgaaga agccttggaa
    54181 aaccagaaag ttcctgattt caactcatgg ctttgccaaa taaaagaaca taaaagggaa
    54241 tggctttttc ctatgattga tgaagagatg gtctatcagc agttttttaa cgaatgcata
    54301 cacttgtctt ctttgaaaaa atagtaagta taaaaatagg ctaggaatcg gttttctatg
    54361 taaaacaaga tttagttatg ctaaaattga tggaagcaga cacatgaatg agtagaaaag
    54421 ttagatgctg tgacatgtgg atgttagact atgatctatt ttgatagata gagctaaggg
    54481 aagaaaagga gtggatttca tggaagtaaa gcagttgcca aaacgagaag aattgcctga
    54541 aaatttaact tgggacttga ccaagatctt ttcaagcgac caagagtttg atgagaaata
    54601 tttggaatta tcagaagagt taaaacaatc tgaaaaacac aaaggaacac ttgatcaagg
    54661 cgcttctcaa tttttaaatg cgattgaatt cgtattgagg gtttatcgcc aaactgaagt
    54721 catttatgta tatgcgcacc ttaaaaacga tcaagacact ggaaatacag attaccaagc
    54781 gctttatgca agagcaagca gtctgttttc gaaagttagt gaagccgttt cctggtttga
    54841 accagaaata ttgcaattgt cagatgacca gatttggcaa tatttcaaag aagaaccaaa
    54901 attggaagtc tatcgccatt atatccagca aatagtagat aatcgagccc atgtcttatc
    54961 tgctgagcag gaatctcttc ttgctggagc aggtgaaatc tttgatgctt caagtgatac
    55021 atttgctgtt ttgaataatg cagatctagt ttttccaacg attgaaggag aaaatggtga
    55081 aatagtccaa ttatctcatg gcgtgtatgg tcagttgcta gaaagcacgg atcgaagggt
    55141 gcgcgaagca gcatttaagg ggttgtacag tgtttacgaa caatttagaa atacatttgc
    55201 ttctacttta ggcacacata taaaaggaca taattttaaa gcgaaagtcc gtaattacag
    55261 ctctgccaga gaagcgtctt tgagcaataa tcatattcct gaaagtgtat acgatacttt
    55321 ggtagacgtg gtaaacaagc atttgccttt gttacatcga tacatggaat tacggaaacg
    55381 tttattagaa gtggaaaaac tgcacatgta tgatctttat acaccggtct taggggaagc
    55441 tccaattacc tttacgtacg aagaagcaaa agaaaaagct ttagaagcac tgaaaccaat
    55501 gggtgaagaa tacatggcca tcgtagaaaa agcattctct gaacgttgga tcgatgttgt
    55561 cgaaaataaa gggaaacgaa gcggtgctta ttcttcggga agctatgaca caaatccata
    55621 tattttattg aattggcatg atacgctgga tcagctattt acgcttgtcc acgaaatggg
    55681 acatagtgtt catagttatt tcactcgttc gaaccagcct tatgtgtacg gcgactactc
    55741 catcttttta gcagaaattg cttcgacaac gaatgaaaat atcctaacgg agtatttatt
    55801 ggaaacagaa aaagaccctc gtgtacgggc ttatgtactc aaccattact tggatgggtt
    55861 taaaggaaca gttttccgcc agacacaatt cgctgaattc gagcatttca tgcatacgga
    55921 agatgaaaaa ggtgtgccat tgactagtga atacctaagt gatagttatg gtaaattgaa
    55981 tgcaaaatat tatggtccag cagtcgaaga agacccagaa attaaattcg aatggtcacg
    56041 gataccgcat ttttattata attactatgt tttccaatac tcgactggct tttctgctgc
    56101 ttcagcactg gcgaagaaaa tactaaacca ggaaccagag gcactagaga actacttggc
    56161 ttacctaaaa gcaggtaaca gcgattatcc tgtggaagta atgaaaaaag caggagttga
    56221 tatgacacag gctgcatata ttgaagatgc aatgtcgatg tttgaacaac gtctaaatga
    56281 attagaagaa ttgatcgatc gtttataagg ctttctattt ttgattttct cgaatagaaa
    56341 cgaaaaaaat acgtcggctc tcttgtaagg gagtcgacgt atttttt
//
LOCUS       DAFEKH010000013        54931 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.014, whole genome shotgun sequence.
ACCESSION   DAFEKH010000013
VERSION     DAFEKH010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 54931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54931
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.014"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..243)
                     /locus_tag="LP386_000872"
     CDS             complement(<1..243)
                     /locus_tag="LP386_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HBL1918129.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(358..936)
                     /locus_tag="LP386_000873"
     CDS             complement(358..936)
                     /locus_tag="LP386_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBL1918130.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(1013..1543)
                     /locus_tag="LP386_000874"
     CDS             complement(1013..1543)
                     /locus_tag="LP386_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HBL1918131.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(1547..2407)
                     /gene="rlmB"
                     /locus_tag="LP386_000875"
     CDS             complement(1547..2407)
                     /gene="rlmB"
                     /locus_tag="LP386_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HBL1918132.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(2400..2795)
                     /locus_tag="LP386_000876"
     CDS             complement(2400..2795)
                     /locus_tag="LP386_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HBL1918133.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(2792..4204)
                     /locus_tag="LP386_000877"
     CDS             complement(2792..4204)
                     /locus_tag="LP386_000877"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HBL1918134.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(4201..4737)
                     /gene="cysE"
                     /locus_tag="LP386_000878"
     CDS             complement(4201..4737)
                     /gene="cysE"
                     /locus_tag="LP386_000878"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HBL1918135.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(4823..5062)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(5059..6519)
                     /locus_tag="LP386_000879"
     CDS             complement(5059..6519)
                     /locus_tag="LP386_000879"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HBL1918136.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(6689..7846)
                     /locus_tag="LP386_000880"
     CDS             complement(6689..7846)
                     /locus_tag="LP386_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HBL1918137.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(7880..9250)
                     /gene="radA"
                     /locus_tag="LP386_000881"
     CDS             complement(7880..9250)
                     /gene="radA"
                     /locus_tag="LP386_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HBL1918138.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(9313..9840)
                     /locus_tag="LP386_000882"
     CDS             complement(9313..9840)
                     /locus_tag="LP386_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HBL1918139.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            10070..10876
                     /gene="proB"
                     /locus_tag="LP386_000883"
     CDS             10070..10876
                     /gene="proB"
                     /locus_tag="LP386_000883"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HBL1918140.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            10873..12120
                     /locus_tag="LP386_000884"
     CDS             10873..12120
                     /locus_tag="LP386_000884"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HBL1918141.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            12196..12540
                     /locus_tag="LP386_000885"
     CDS             12196..12540
                     /locus_tag="LP386_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918142.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(12657..12983)
                     /locus_tag="LP386_000886"
     CDS             complement(12657..12983)
                     /locus_tag="LP386_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918143.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(13356..14557)
                     /locus_tag="LP386_000887"
                     /pseudo
     CDS             complement(13356..14557)
                     /locus_tag="LP386_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            14674..15189
                     /locus_tag="LP386_000888"
     CDS             14674..15189
                     /locus_tag="LP386_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBL1918144.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(15388..15834)
                     /locus_tag="LP386_000889"
     CDS             complement(15388..15834)
                     /locus_tag="LP386_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBL1918145.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(15881..17359)
                     /gene="msr(C)"
                     /locus_tag="LP386_000890"
     CDS             complement(15881..17359)
                     /gene="msr(C)"
                     /locus_tag="LP386_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBL1918146.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(17713..18342)
                     /locus_tag="LP386_000891"
     CDS             complement(17713..18342)
                     /locus_tag="LP386_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBL1918147.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(18326..18790)
                     /locus_tag="LP386_000892"
     CDS             complement(18326..18790)
                     /locus_tag="LP386_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL1918148.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(19277..20545)
                     /locus_tag="LP386_000893"
     CDS             complement(19277..20545)
                     /locus_tag="LP386_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBL1918149.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(20776..21513)
                     /locus_tag="LP386_000894"
     CDS             complement(20776..21513)
                     /locus_tag="LP386_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL1918150.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(21580..22149)
                     /locus_tag="LP386_000895"
     CDS             complement(21580..22149)
                     /locus_tag="LP386_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBL1918151.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            22277..23149
                     /locus_tag="LP386_000896"
     CDS             22277..23149
                     /locus_tag="LP386_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL1918152.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            23491..24363
                     /locus_tag="LP386_000897"
     CDS             23491..24363
                     /locus_tag="LP386_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL1918153.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            24360..26318
                     /locus_tag="LP386_000898"
     CDS             24360..26318
                     /locus_tag="LP386_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL1918154.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(26569..27420)
                     /locus_tag="LP386_000899"
     CDS             complement(26569..27420)
                     /locus_tag="LP386_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL1918155.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            27543..28010
                     /locus_tag="LP386_000900"
     CDS             27543..28010
                     /locus_tag="LP386_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBL1918156.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(28273..28755)
                     /locus_tag="LP386_000901"
     CDS             complement(28273..28755)
                     /locus_tag="LP386_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBL1918157.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(28855..29718)
                     /locus_tag="LP386_000902"
     CDS             complement(28855..29718)
                     /locus_tag="LP386_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBL1918158.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            30316..31164
                     /locus_tag="LP386_000903"
     CDS             30316..31164
                     /locus_tag="LP386_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918159.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
     gene            complement(31335..31676)
                     /locus_tag="LP386_000904"
     CDS             complement(31335..31676)
                     /locus_tag="LP386_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HBL1918160.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SMEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAAEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            31762..32469
                     /locus_tag="LP386_000905"
     CDS             31762..32469
                     /locus_tag="LP386_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBL1918161.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            32456..32779
                     /locus_tag="LP386_000906"
     CDS             32456..32779
                     /locus_tag="LP386_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBL1918162.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(32868..33905)
                     /locus_tag="LP386_000907"
     CDS             complement(32868..33905)
                     /locus_tag="LP386_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HBL1918163.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(34352..35335)
                     /locus_tag="LP386_000908"
     CDS             complement(34352..35335)
                     /locus_tag="LP386_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HBL1918164.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
     gene            complement(35751..36521)
                     /locus_tag="LP386_000909"
     CDS             complement(35751..36521)
                     /locus_tag="LP386_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1918165.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(36514..37449)
                     /locus_tag="LP386_000910"
     CDS             complement(36514..37449)
                     /locus_tag="LP386_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1918166.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(38043..39692)
                     /locus_tag="LP386_000911"
     CDS             complement(38043..39692)
                     /locus_tag="LP386_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBL1918167.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            complement(39887..40783)
                     /locus_tag="LP386_000912"
     CDS             complement(39887..40783)
                     /locus_tag="LP386_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL1918168.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(40776..41456)
                     /locus_tag="LP386_000913"
     CDS             complement(40776..41456)
                     /locus_tag="LP386_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1918169.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(41457..42239)
                     /locus_tag="LP386_000914"
     CDS             complement(41457..42239)
                     /locus_tag="LP386_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1918170.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(42232..43149)
                     /locus_tag="LP386_000915"
     CDS             complement(42232..43149)
                     /locus_tag="LP386_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1918171.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(43152..43436)
                     /locus_tag="LP386_000916"
     CDS             complement(43152..43436)
                     /locus_tag="LP386_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918172.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
     gene            complement(44450..44857)
                     /gene="arsC"
                     /locus_tag="LP386_000917"
     CDS             complement(44450..44857)
                     /gene="arsC"
                     /locus_tag="LP386_000917"
                     /EC_number="1.20.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (thioredoxin)"
                     /protein_id="HBL1918173.1"
                     /translation="MRKIYFLCTGNSCRSQIAEGYGKAILPTDEFEIKSAGIEQHGLN
                     PRAVQVMAEEGIDISTQTSDLIDMDYFNQADLIITLCGDAKDKCPVIPKGIKHVHWDL
                     EDPAKATGTEEEIINKFREIRDDIKSRVANLLD"
     gene            45215..45574
                     /locus_tag="LP386_000918"
     CDS             45215..45574
                     /locus_tag="LP386_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBL1918174.1"
                     /translation="MKNEICEISCVHEDKVLLGKEKLQTEDISSLKSVFKILADENRL
                     KIIYALSYEDELCVCDIAATIEATVATTSHHLLSLKKNGIVVSRKVGKLVYYSIKNDK
                     FVQLLNSKLYLEDEVLV"
     gene            45571..47688
                     /gene="cadA"
                     /locus_tag="LP386_000919"
     CDS             45571..47688
                     /gene="cadA"
                     /locus_tag="LP386_000919"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBL1918175.1"
                     /translation="MSEKKQVYRVEGLSCTNCAAKFEKNVSQIPKVTDAKVNFGAGKI
                     SIEGEATIAEIEAAGAFENLKVQSEHDTEPRIETKEPFVKRNWNLLVSLFLIILALGS
                     QVVNGEDALLTEGLFILAIIIGGFSLFKEGFSDLLKLNFSMESLMTIAIIGAAIIGEW
                     TEGSIVVILFAISEALERFSMDKARQSIRSLMDIAPKEALIRRNNVEQMINVSKIEVG
                     DIMIIKPGQKIAMDGQVIKGHSSVNQAAITGESVPIEKNINDDIFAGTINEEGALEVK
                     VTKHVNDTTIAKIIHLVEEAQGERAPAQAFVDKFAKYYTPTIMVIAALIVIVPPLFFN
                     GDWNTWLYQGLSLLVVGCPCSLVISTPVSIVSAIGNSAKNGVLVKGGIYLEEIGGLKA
                     IAFDKTGTLTKGTPTVTDFTTVDSKDEEKYFSIITALESYSQHPLASAILKEADNRAI
                     SYKSVVVDEFTSITGKGIQGNIEGITYLVGSPKLFESILTDNSKIIENYQRLQQQGKT
                     AMLLGTDKQILAVIAVADELRESSKAVIEKLHDLGIEHTIMLTGDNATTAQSIGKQTG
                     VTEIKGDLMPQDKLDYIKSLKETYGKVAMVGDGINDAPALAASTVGIAMGGAGTDTAL
                     ETADVALMGDDLQKLPFIVKLSRQTLRIIKQNITFSLGIKLLALLLVVPGWLTLWIAI
                     LADMGATILVTLNGLRLMKVKSK"
     gene            complement(47909..48721)
                     /locus_tag="LP386_000920"
     CDS             complement(47909..48721)
                     /locus_tag="LP386_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1918176.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGTQENQYILEMLQKKAGKLDPKIEGLIVDELKQ
                     AGLVSEKEMDRMIEFFIINLIPPTEQDQFTYQCIDEKKQLYLGSTKFGKEAQLYLHHD
                     NQNHILHILPFTFSNFSVDRLLVYLANQESYSYFGKHLPKELVEKAILLYSINQLTVD
                     VRIAPLVYSKETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNVAYPSSK"
     gene            48883..50139
                     /locus_tag="LP386_000921"
     CDS             48883..50139
                     /locus_tag="LP386_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBL1918177.1"
                     /translation="MNQVNQHDLGESIRVSREERGWTQRYLAEKVGISRSLLSKVEKG
                     TRQLSAEKLNLILDSLQEEIVPVNRVLIDYLTIHFFSNQHLKLIEAIIGMPIERFEEL
                     DYAPKGYIGQYVWNQVITIRYSIDDTVKGTVMEFSGQGCKHLAMRLKTAKSNWQEFFR
                     KVLDYQGNFTRIDFTLDDFVGSLSIPELKRKVTLGHVWTTFQVSESHGGTDIINNESN
                     GETLYLGSKKSQCRFCFYQKDYEQRKRRGISLEEAEVKNRFELRYRKEKAQSLAKIIS
                     KTHDLTKLFFELLNGAICFYDRAPNDPGAKVDAKWAAFIGNHGATTISLETIPQSFEK
                     SMNWLIHSVSPTLAFIQEVDNHFDSNLINEIISCGELSSRQQKILENLIAEPDYYQEE
                     VEFYIQCLQNMKAAKIHKKSKAQLTH"
     gene            50229..50426
                     /locus_tag="LP386_000922"
     CDS             50229..50426
                     /locus_tag="LP386_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002403995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBL1918178.1"
                     /translation="MKNTITTYELPYLLTREQASHFLGIDPKSFDKFVRANDELERFM
                     IGRQERYTVTSLINFIKTHSI"
     gene            50532..51581
                     /locus_tag="LP386_000923"
     CDS             50532..51581
                     /locus_tag="LP386_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL1918179.1"
                     /translation="MPSIIKRGNSYRAQISLYNHGQHKKLTKSFSSKKEATRWALENE
                     LEKGNGKQLAERTTTFADFFENWIHIIKKNDVKETTFQNYQRTSQVVKKLFGDIQLKD
                     LNDIVVQRKIDKYAETHSRKTTHEVLLKIKTALRDAYARGYLATDFANLVKTRGKVLD
                     KRNRVLSITELKKLRTYVINHRENEFNILVLLALETGMRRGELLGIRPEDLFEYGIHV
                     RRSLSPTSEDTSLKTKNSRRDISINQEVYDILKSVPIKDNGYFFDPDGFQQSAKLARL
                     LKKLDIPKTTFHGLRDTHASFLFSQDIDIAYVSKRLGHINIQTTQNYYLELMPEKKHQ
                     QDADALNLLNSLSNL"
     gene            complement(51879..52499)
                     /locus_tag="LP386_000924"
     CDS             complement(51879..52499)
                     /locus_tag="LP386_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918180.1"
                     /translation="MNINRVIKLIGAKNINKVRSEFIFPEDFFNWFFYQFSECKRLLG
                     ENYYLKGIGGFMGNVADEQNIIKGISEQTSELTVTKAFISNGESLKNVTARIRKENEV
                     DIVFGIDHECNSVIYVTQSANLILFENGCKDDFMVVYLYDILIPKLRSLYMSSESIFV
                     SEQKGSFSKKIGIEVIESIMCHNHITLEELEILIGQKNNNTKIQVS"
     gene            complement(52580..52990)
                     /locus_tag="LP386_000925"
     CDS             complement(52580..52990)
                     /locus_tag="LP386_000925"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918181.1"
                     /translation="MVTLFYRRDFLFSIYTKYFTLSSNIKTSTKLICKLFKLDKISNI
                     DDVKSKILTRKVSEPVKLTAQDKKNGIVLYGDDAKYNYNWDTSSEAEVLSIPTTDTSG
                     EKVTFKINFITAISKLEYGKQKKRDNNDQYLPKK"
     gene            53020..54198
                     /locus_tag="LP386_000926"
                     /pseudo
     CDS             53020..54198
                     /locus_tag="LP386_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
BASE COUNT        16359 a        11265 c         9800 g        17507 t
ORIGIN      
        1 aactgcttca gttaaaaatt cgatctcaac tgtccgagta agtacatctg aatagctgta
       61 agatactcgt tcaaaagaat tttcttcagg atccaaatca acaacgaata ctgaaggata
      121 ggtttctgtt aaaacgccgc ggcgttctgt ttgacgcttt cttcctgtct gagcaaccaa
      181 catgattggg ctgccgatac gaccttctaa atctttcttg attgaagcta aagttgttgg
      241 catacagttc acctctacta tcaactatac cacatatttt taaaattttc aagtttacca
      301 taaaaaaaaa agaaatgcaa taaaaataaa taagaagctc attaagattt ttctaaatta
      361 ttcctcatta taaaatttca agtgtttttt tattttgagt tttactctcc cgtaagcgct
      421 cattacttgc ttgtgatcca ttgctaaaca ttcagccatg tctacaaaat caacgccttg
      481 catataataa tgaaaaattt tagcttctat ttttgaaaac tggatttcgc aattttcgat
      541 tgcttctttt aataaaagat gctgaatcgc taaaggttct tgcaatgtga tctctgctaa
      601 aaagtctggt ccttctgtct ctattttttg gtcgattgag acttcatctt tttgatcacg
      661 acgcttcagc gcgttctgct tcctcaacag agaatagatt tgattgctta taatgctttt
      721 ataataactt ccaaagctaa cacctttgct tttttcgtaa gttctcaatg cctgatataa
      781 agcgatcctt gcttcttgtt cccaatcctc agaaacataa tttcttaaat aataggtgtt
      841 tttcaaacgt agtaaaagtg gaaaatattt ttgatacagg gcagcaaatg cttcttcgtc
      901 accattacgt gcagcgcgca ataactcctc agacataaaa taattcctcc ataaattcgt
      961 ttatggagga atcttatcat caatgattca tcgaactgat tagaacgata tgttatttat
     1021 tttttctcat taaatcgtcc aatttttggg acaatttttt taactgctct tcattccatg
     1081 gagaattacg tcggaaatca ataaaatgca tatctttatt ttcttgggct attgtttttt
     1141 ccgttttttt tatcgtctta tataattcat aagcagaagt tcgtaatgct ccttgggaaa
     1201 agatcatcca ctgttctgct aaatcgcttg tcgccactgt cacttgtgtc aaacggtcat
     1261 tcagctgacc agcgattctc tcgatataac tgtcagccgt ttcgtcttct ttcgtaaaaa
     1321 caacatccaa ctggtatttc ttataatttt gttggatgcc cggaactagt tgggcatcga
     1381 agacaacgat gacttccatt ccttcatatt tcgcataatt tgataaacga tgtaaaagag
     1441 cttctcttgc atccgccatt ttgtcctgct ttttaagctg gacaagttcc ggccacgaac
     1501 caatcatgtt gtagccgtct acaatcaaca gctgtttttt catggtctac tccccctgac
     1561 gttgggaaaa agcctgatac ataagcaaac cagcagcaac actggcattt aagctctgga
     1621 cgtgcccggt catcgggatc gtcagcaatt catccatttc ttttttcaat cctggactca
     1681 ttcctttgcc ttcattacca atgactaaag caattgatcc tttggcattc catttttgga
     1741 agtttgtgcc ggtcatatct gtgccaaata cccaaaatcc tgtttctttg agctgttgca
     1801 cagcttgtac caaattcgtc acgcgtgcaa cagggacatg ttcgactgcc ccagtggaag
     1861 tctttgttac gataggtgtg attccaactg ctcggtgttt tggtatgatc acaccatcga
     1921 cgccacttgc gtctgctgtc cgtaaaatcg acccaaaatt gtgtggatct tcgatgctat
     1981 ccaaaatcaa aaagaagggg tcttcttttt tctcttttgt tcgttcaatc agttggtcaa
     2041 gggataaata ttcataaggt gtaatcgcaa gaacgactcc ttgatgcacg ccgtgatcgc
     2101 tcaaagtttc taatttttgt ttaggaaccc atttgactgg cacagcttgt tcacgtgcga
     2161 tttctttcag ttcttctact ttttctcctc gtgaatcttc ttgaagaaag agtttattcc
     2221 ctcgcccttg ttgtagcgct tctactgcgg catggtgccc aaagacgaaa ttatcttcta
     2281 atgcttcttc attttgatca gaaactgact gatttcgtcc agtttgcttt ttatttgaat
     2341 atctattttg ttttttgtct tcaaatccac gtttcgattg atgtttgttt gttctttctt
     2401 tacccatttt tttcaccaac tttctgaata caccagcgga tcaattcttc catccgctcg
     2461 gtttgttttg tcaaatgcag atagcccatg agcgcttcga accctgttgc gacccgatac
     2521 gtcgtaacat cagcattttt tgcgctcgta tggcttttag catttcttcc tctgcgataa
     2581 taaagttctt cttcttctgt caaaagatgt tcttccagca tttgctgaat caaaaaggct
     2641 tgtgcattcg cagaaacata attcgttgcc gcacgatgca gcttattggg ttttgtttct
     2701 ccttgatcaa tcaggtggtc acgaacatag atttcgtaaa tcgcatctcc aacataagcc
     2761 aaggctaaac cgttcaattg tgtgtaatct ctcatgcttc tcttctccat cgggttcctt
     2821 gcggtgtatc ttctaataag atcccttttt ctttcaacaa atcacgaatt tcgtcgcttc
     2881 ggacaaaatc acgattgctt cttgcttgat ttcgttcttc gatcaattgt tcaatctctt
     2941 catctaataa ctcttctgct gtaaataaaa taccgaagat cgaaagccat tgcgagaata
     3001 aagcttctcc ttgtgccaag acagcggcag aaactttcgg ctggtctaga taagtgttca
     3061 gccacttagc aagctcatag accactgtga tcccatttgc tgcattaaaa tcatcgtcca
     3121 tttcttcgat gaatcgctgt tctaaatttt ctaacaaagc gattttatcc gcatcatctg
     3181 ccaaattctc tgaggcagtt tcttggcgga atttcaaatt gtcaaacgta ttcttcagtc
     3241 gttgtaaatt ggtggctgct tctttcatcg tcgtttcact gtagcggatc ggacgacggt
     3301 attgtgtggt cgccatgaag aaacgcaaga cttgtggatc aacgtttttg atcatttcat
     3361 gtacagtgat gaaattccct agagatttac tcattttttc atcgtcttcg ccaatcgtta
     3421 catagccatt gtgcatccag taattagcga attttttccc tgttttcgct tcactttgtg
     3481 cgatttcatt ttcatgatga ggaaattcta aatcttgccc gccaccatgg atatcgatcg
     3541 tttctcctaa atgttttgtt gccataacgg aacattcaat atgccaaccg ggacgtcctt
     3601 tgccccatgg tgaatcccaa gaaatctcgc caggttttgc ttgtttccat aaagcgaaat
     3661 ctaatgggtc ttctttttgc tgctgttctt cccctgtacg ctgacttgct ccgacttcca
     3721 gttcatcgat ggattggtca cttaatttcc cataattttc aaatttacgg gtacggtaat
     3781 acacatcacc tgaagattca taagcatagc ctttttcaac caacacttga ataaatgcta
     3841 aaatatctgg catatgatcc atgactcttg gatgcagtgt agcaggctcg acattcaacg
     3901 ctttcgtatc ttcttcaaat gctcggatga aacgatcagc aacttctggt gctgtaatac
     3961 ctaattcgtt tgctgtacgg atgattttat cgtctacatc cgtgaaattc gatacgaaat
     4021 cgactttata gcctcgatat tcaaaatagc gtcgaattgt atcgaaagca atggtgctac
     4081 gagcatttcc gatatggata taattataca cagtcggtcc gcagacatac ataccgacat
     4141 gtcccttttg tatagggatg aattcttctt tttttctggt caatgtattg tagattttta
     4201 tcattctgat ctcctcactt tttctccttt gattcgaacg acttttgctg gtactcctac
     4261 cgctgtagcg tcgtctggaa catctttcaa cacaacggca cctgcaccga ttttggcgtt
     4321 ttttccgatc gttaccggtc ctaatatctg cgcattcgca gagagcatgg ctccttgttt
     4381 aacagttggg tgtcttttac ccgtttcttt tcctgtgccg cctaatgtta cgccatggaa
     4441 taaaatcaca tcgtcctcga tttctgcggt ttcgccaatg acgattccca ttccatggtc
     4501 gatgaacacg ccagttccaa tcgttgctcc tggatggatc tcaacaccag ttaggaaacg
     4561 ccagaattga gcattgatct tcgccaataa aaagagccgg tgctgatata aaaaatgaga
     4621 gaaacgatgc caaaacaagg catgaaaacc agggtatgtc aaaacgatct cagctgtcga
     4681 acgtgcagcc ggatcgtttc tctttgctgc atcaatcgct cgggtaaacc aactcatgac
     4741 tttccactcc tttcgtaaga attttatgta ggaaatcatc ttcttataaa gaaaagaagc
     4801 gccttttaaa taagtttcct tatcaaaaga cgctttccgc gtggttccac ttttcttcat
     4861 aatcaatgat tatctctgac agctaacgcc tgttatacgt tcttggctac tttgtttcct
     4921 ataaaacagt ttttcctgtt ttctgtgttt cgccaagacc actcccagag gcatttcggc
     4981 aaccattcat tgataccttg caccacccgg tatctctctt gtaatgatca gctgcttact
     5041 tttttctgtt catcgtgttt agttcagtac ttgatttaaa tgtgctaatg atttttcacg
     5101 accaagcaat tcgatcgttt caggcaattc tggaccatgc atttgtcctg atacagctac
     5161 acggattggc atgaaaagat tttttccttt tacgccagtt tctttttgaa cagctttgat
     5221 ggcagctttg acagttggag catctactac ttccatttgt tctagctgtg ctttgaatgc
     5281 gtggagaaca gtaggaactg tttcaccagc aagtacttct tttgctgctt cattcaatac
     5341 aggatgttca ttgaaaaata gcgtagacag atcaacgatt tctgcagcat agctcatttg
     5401 aggttgatac aggctaacga tcttcttcac ccattcgatt gtcttttcat ctgggttttc
     5461 tgctacacgt ccatcagcga ttagataagg cagacacatg tcagtaaatg catctagatc
     5521 cattgctttg atgtaatggt tgtttaccca ttgcagtttt ttcgcatcga aagctgcggg
     5581 tgatttactt aggcgttttg gatcgaacat tttgatcaat tcttggtgtt cgaagatttc
     5641 gtcttcgccc acaggtgacc agcccaataa tgcaataaag ttgaacattg catctggtag
     5701 atagcctaat tcgcgatatt gttcgataaa ttgcaagatt gattcgtcac gtttgcttag
     5761 ttttttacct gtttcactgt tgatgatcaa tgtcatatgt ccgaaggttg gtggtgtcca
     5821 gccaaatgct tcatagatca tcagttgttt tggtgtattg gcaatatggt catctccacg
     5881 taaaacgtga gtgattttca tcaaatgatc atcgaccgca acagcaaaat tataagttgg
     5941 cataccatcg cgtttttgta tgacaaagtc gccaccgata ttatcggatt cgaacgaaat
     6001 agcgcctttc accatatctg taaatgcgta ttctgtattg cgaggcacac ggaaacgtac
     6061 aacagattct agaccttgtg cttctttttc tgcttgttct tcaggtgtca agttcgcaca
     6121 tgttcctgcg taatgaggca tttctcctct tgcgcgttgt gcttcccgtt ctgcttctaa
     6181 ttcttcttct gtgcaatagc atttgtatgc tcgattgcta gcaagcagct gatcaatcag
     6241 cggttgatag atttctttac gttcagattg acggtaaggg ccgtattctc caggattttc
     6301 aggagattca tcccaattca ttcccaacca agcaaggttt tccaactggc ttttttcgcc
     6361 atcttcgata ttacgttttt ggtcagtatc ctcaatacga ataataaagt ctccatcatt
     6421 gtggcgggca aacaaataat tgaataatgc agttcttgca tttccaatat gcaggtgccc
     6481 agttggactt ggtgcatagc gtacgcgtac tttcgtcatt ttcttcctct tctttcaaac
     6541 tagactttga ctaacagcaa aaattccgtc agttacggct tctcaaatat catttattta
     6601 aagccactca gcacaaattt taccttttct aaggtaaata gtaaagccaa ctggttgaat
     6661 ttccttacca gttggctgaa tttctttttt attttgattg tttagtcttt ttctctgtct
     6721 cttttttatt gtcgattcct cgtcctgcat gtgcaggttt agcaaagatc atgcgtccag
     6781 cagctgtttg aagggcactt gttacaacga cttcgatacg ttcattcatg taatgctgtc
     6841 catcttctac gacaaccatc gtgccgtcat caaggtaggc tactccttgt tggcgttctg
     6901 tcccggcttt tactactaga acattcatcg tttcaccagg gatgacgact ggttttacgg
     6961 catttgccaa cgcattgata ttaagaacag gtacattttg gaattcagag actttattca
     7021 agttatagtc attggttaca atgacaccat ctaaaagctt agccaatttg atcaatttgc
     7081 tgtctacttc actgatatct tcaaagtctc catcgtacat ttcgacagat ataccctctt
     7141 ctttttgcaa ggcatttagg atatctaatc cgcgacgacc acgcacacgt ttcaaactat
     7201 cccctgagtc cgcgatgtat tgtagttcgt aaagaacaaa attagggatc atcaaggttc
     7261 cttctaagaa tccagtcttt gtaatatcat aaatccgacc gtcaatgatc acgcttgtat
     7321 ccaagatttt atatttatgg aaattttctc ctgattttcg ttctaacagt tgactctcaa
     7381 cttgactagc tgtttcttgc tcgatttttt tgcttcgtga accaaaaact ttcttccatt
     7441 cttcgattcg tgtcgttccc attctcaatc ccagatagcc taagatgatc atcagtaaaa
     7501 tcggcaatac actattgacg aatggaattt ccatattgta aagaggggtc gagatcacaa
     7561 cacctaaagt caatccgatg atcgcaccga tcgcaccgaa gagaagataa gtcaagctga
     7621 cctcacttag tttttgttct acttgtttga taatagctga gatatgtttg gccaacagca
     7681 aagataataa aaagaaaata agtgcgccta acaggctgtt ggtaaatgta ttattcagcc
     7741 atccgtttga ctgttgaccg attgcctgcc aagctgaggg taaaaatgaa atacccaagc
     7801 ttgcgccgac aatgatcatc agcaaagtaa tgacacgttt ttgcatcgtt tttcctccgt
     7861 ttcgacaatc atttattagt tagcggaaca cacgcttcaa cgtttcagcc aaagttgcta
     7921 ctccaactat ctcgattcct tttggcgctt cccagttacc taagttgttt ttaggtaggt
     7981 atacttttgt gaagccgagt ttttggactt ctttgactcg ttgttcaata tgactgacac
     8041 gtctgatttc tccagtcagt ccaatttcac cgatgaaaca ttccgttggc tgtgttcctt
     8101 tttctttata gcttgaagca atactgacag cgatagctaa atcaatcgct ggttcattta
     8161 attttacccc acctgcagct tttaagtaag catcttgatt ctgaagaagc aacccagctc
     8221 ttttttccag cactgccatg atcagagata cccgattgaa atcaagacct gttgttgttc
     8281 gtttggcatt tccgaacata gtaggtgtga ctaatgcttg gatctctacc aaaattggac
     8341 gtgtcccttc cattgccaca acgatagcag agccagttgc accgtctagg cgttcttcta
     8401 agaaaatctg tgaaggatta gcgacttctt ccaatccatg ctcatgcatt tcaaaaatcc
     8461 caatctcatt cgttgagcca aatcggtttt ttactgctcg caaaatccga aaactatgat
     8521 gttgttcacc ttcaaaatat aacaccgtat ccaccatatg ttctaacatt cttgggccgg
     8581 cgatcgagcc ttctttggta acatgaccga cgataaaaat ggctatccca tttgttttag
     8641 cgattttgag tagttctgca gtggtttctc ttacttggct gacacttcct gccacacttg
     8701 tgatgtctgg ctgcgtcatc gtttggatgg aatcaatgat aacataatca ggggagatat
     8761 gttcgatggc acgactgatt tcgttcatat ctgtttcagc gtatagataa aattctgtgt
     8821 tgatacttcc gaggcgttcc gcgcgtaatt ttatctgctc tgcgctttct tcgccggata
     8881 catataagac ttttccgcct atggctgcta attgctgaga aacttgtaac agcaaagtgg
     8941 atttcccgat acctggatcg ccaccaatca agaccataga ccctggcacc acacctccgc
     9001 ctaacacacg gttcagttct tctaattttg ttttgatccg aggttctttt ttagggacga
     9061 cgtctgcgat ttttgttggt tttgcttttt ctcctgtcaa acttgtccga gttctgcggt
     9121 ccgttgtatc ttgttcgatt tcttcgacca tcgtattcca ttttccgcaa tttgggcagc
     9181 gtcccaagaa cttaggcgac acatacccgc aattttggca aacaaattgt acttttgatt
     9241 tttttgccat tgtaccgcct ccttttatcc taatcatgag acattaaatc aagcttaagt
     9301 atctttaacg ttttatttac tggaagaacc aaatccgcct tgacgttgag cagtcgtttg
     9361 atcttgatct gcttttaaaa acggcaaaaa gatcccttgg ccgatacgct cgcctttttt
     9421 gatcactaca tccttgaaac caaagttggt gaattggaac atgatatggc cttcatttgc
     9481 ctcattattg taataatcac tgtcaatcac acctactccg tttgtcaaca ctaaaaaccg
     9541 cttcaacgga ttgcttgaac ggttagcaag ctgcaaaaat tcatcttctc ccatgtaagc
     9601 tttgattcca gtaggcacga gggttggttt caattgtttt tcattttctg atacatcttt
     9661 tttcaatcca tctgcgactg tttccaaccc ctttttccag cctgctttcc agatacttgg
     9721 aatcacgacc tcttctgctg cttcaaaatc atagccagca gcatgatgtg tagcgcgctg
     9781 cggtagattg atattttgat ctttatattt agaaataact tcaaatcctc tttttctcac
     9841 cggttttcct ccctaaataa actactccta ttctaacata tccgaggctg taaaagactt
     9901 tctttacaaa ttcttcaaga aattctgcta tcttaaagta aaccattaat tcgttctttt
     9961 tccaaacgac tgcaagttgt acaaaaaaac tattttttac atgactttac tcgtcaaaac
    10021 aagtagaata gaacgaaatt aatgagtgga tatttgattg aggtgtcaca tgcgtaaaga
    10081 aattaaaaat gcaaaacgaa ttattgtcaa agtaggaaca agtacattga tttatcccaa
    10141 tggaaatatc aatcttgcgg caatcgatca gttagctttt gtcctttctg atcttagaaa
    10201 tcggggaaag gaagtgatct tagtctcatc aggagctgta ggcgttggta tgcataaatt
    10261 acatttgtca gaacgtccga ctttgattcc tgaacagcaa gctgcggcgg ctgttggtca
    10321 agccgaactg atgaatatct ataatcaaag attcagtgta tataatcaac agacggcaca
    10381 gatcctcgtg acaagagacg tggtagatta tcctgaaagt cgtaaaaatg tgaggaatac
    10441 attggaacag cttttgatta tggacacgat ccctatcgtg aacgaaaacg atactgtagc
    10501 agtggatgaa ttagatcatc tgacaaaatt tggcgataat gatcagctgt cagccatcat
    10561 ggcaaaactt gtcgcggcag accttttgat cgtcctttct gatatcgacg ggttttattc
    10621 agataatccg actacaaatc ccgaggctca gatgtatcgc tatatcgata aaatcgatga
    10681 aaagattctg gcacaagcag gtggtgctgg tagcacattt ggaacaggcg gtatgcagag
    10741 taaattaaaa gccgcttcta ggatatttga agcaaacagc gcaatgattt tagcaaatgg
    10801 aaaaaatccg gcaattattt ttgatattct tgcaggaaaa gaagtaggta ctttatttaa
    10861 ggaggacttg aaatgactga cttgatgcaa ttaggacaac aggcaaaaga tagcgcgcaa
    10921 caactagcac ttatgcctac aaaccgcaaa aatgagctac ttgttcaaat ggcacaaacc
    10981 atcaaaaaga atcaacaagc gatcattgaa gcaaatcata aagacttaga aaaagcagtc
    11041 gaaaacaata tcagtgaaac gatgcaagac cgcttgcagc tgacacctga gcgaatcaat
    11101 gccatggcta cagagatcga aaaaattgct tcgttagacg atcctattgg aaaagtagat
    11161 gagatgtgga cgaacaccga cggattgaga atcggcaaaa agcgcgtgcc actaggcgtg
    11221 accggcatca tttacgaatc tcgtccaaat gtcacgacag atgcagctag tctagcattc
    11281 aaatcaggga atgccgttat ccttcgcggt ggcaaagaag cattcttctc gaatcaatta
    11341 ttagtccaat tattgcagca agtactggtc agtgctggcg aatctcctta tgccatccag
    11401 tttgtcgatg atacttctca tgaaactgca ggacagttga tgcgattgac agaatactta
    11461 gatgtgctga ttcctcgagg cggagcaaaa ttaatccaac gagtcaaaga acaggcaacg
    11521 gtacctatca ttgaaacagg tacaggaaat aatcacgtat atatcgataa agaagcacag
    11581 ttatctatgg cagtgaacat catcgtcaat gcaaaagctt cccgtccatc tgtctgtaac
    11641 gcggcagaaa cattgctgat ccattctgag atcgcacctt ttttcttgcc agctattgaa
    11701 aaagaactgg tagaacacgg ggtctcttta cgtgcggatg ctcgtgcgtt agaatatcta
    11761 gagacggctg ctttagcaga agacacagat tgggatactg aatatctaga ttatatcctt
    11821 gctgtcaaag tggtcgattc tttggatgaa gcaattgcac atatcaatcg gcataatact
    11881 aaacattcag aaacgatcgt gacagatagt tatgcggcta gtcaacgttt cttaaatgaa
    11941 gtggacgcgg cggctgtcta tgtcaatgcc tccactcgtt ttacagacgg atcggtattt
    12001 ggttttggtg cagagattgg tatctctact caaaagttgc atgcccgtgg tccaatgggg
    12061 ttaaatgaat taacttccac aaaatatatc atttatggcg atggacaaat ccgcgaataa
    12121 tgtttcgtgt gaaacattat tcccgccttt tgcctttttt ctgtaaaggt tctatccaac
    12181 tagaaaggtg tcaatatgtt tgaaatttta atgatttttt ttatttacct tatttctctg
    12241 aatatcgctg cttttctggg agtcggtatt ttatcccttt tctttcaatt caaaaaacga
    12301 agcataggga gtcaacggga aaaatggtcg cagtattttg acaaaatcgg gcaaaaaggg
    12361 ctggttacac gcttgcacat tagttacatg gttgcattat gcttattagc gacaatcaat
    12421 tactattctt ttttcgatca ttcaatcgct tatacgatta cgctactgat tgctgggatt
    12481 tttcacttat cttataaata tcagctgaat aaaaaccact tgaatcggac tttccgctaa
    12541 aaaatatccg tacgataagt agagtgcctt gaagatcggc aaaaaactgc cggacttttt
    12601 agaggctgtg acaaagattt tgtcacagcc tctttttcca tataaacggc gttcgcctac
    12661 cagctgcctg gtaaatctgt ttcctcttcg ttaagaagcg aaaatccgtc aaatgtttcg
    12721 ccatcataat aacgaagcag ctcatccatg gacaagttca tcgttttttc tttttcttct
    12781 tccgctgatt cagccagtag ctgttcccga tacacctgat acataccagc tattttttgc
    12841 tgcatcgctt ttctagtttc accttccgca ttgattattg gcaattcttt gatatagcca
    12901 cgataaatca accgatcatc tgaaaattca atgggtaatt caacgagtgt caacccgact
    12961 tcctgaaaat attcttccag catctattat ccccccattc tttttcttaa atgaatttta
    13021 gcttacctac tgaaaatttt ccagtttcat tattttgaga aaaaaaggga atgtgacaaa
    13081 aatcgtgtca catccccttt ttccgaataa atggtgttct tctgccaact cctcaatcat
    13141 aagtcacaat attcaacaaa catgagaaac tgttttttga aattgttcct tgtgattcag
    13201 agttaaacga cagtctcaca acctcttggt aaacggcgtt caaaagcttg catctgcggt
    13261 aataagccca accaaacgaa aaatatgaga agctattttt gtttggctgt tcttatgact
    13321 tgatgcagga cagctttttc acaacctctg atttcttatt cttcttcatt tgtagcaaaa
    13381 taattacggt gataaatgat acaacataca ctgataagaa caatggcacc tgcaaaataa
    13441 aacgcatagc tttcaccaat atgttcacca atcacacctg caataaatgg tgctaaagct
    13501 ccaccgaaaa agcggacaaa actatagctg gacgaagcaa cgtttcgttg cagacctggt
    13561 atttccatag caatcgtcgt caacagtgta ttgataattc cttggaaaaa tcctgctaac
    13621 acaatgctga tcggtacaag gactggcata gaagttccag ctcctaataa cagcaaacaa
    13681 ataatgaata agacaaatgc tgctaaaatt gtccgataag tcgtaaactt ccgctcaaga
    13741 gccggtgcaa cgaaaatcga agcaatagcc agaagcacac cccagccaaa aaatacaaaa
    13801 ccgacttcta attcagaata gccaatcaat aaaaatggcg catacgcaag taaagtaaag
    13861 aatccgaaat tatataacaa tgcgattagt ccaactgaac gaagtttatg attgcttaac
    13921 gctttgacac cttcccaaag gcctactttt ctctttggtt tctcagtttc aggtaaaagt
    13981 accgctaggg ctataaaacc gcaaaacatc aaaaatgcta ccccaaaaaa tggataacgc
    14041 catgaaccac tgcccaagac cccaccgact agagggccaa cagccattcc gcagccaagt
    14101 gctgcttcat acatcatgat tgctttttct gtgttaccaa ctaaaatact gacgatcgtt
    14161 gctaaagcag tagagacaaa taaagcattc ccgacacccc agccggcacg taacccaatc
    14221 agcattccga tattcccaga taatccgcca agaccagcga atacaacgat gataaacaat
    14281 cctgtcatca atgttttttc aaaccgatcc gactagataa gaaacctgta aatagcatca
    14341 ccacaccagt gactaacatg taactagtaa ataacagggt cgtttcagct ggcgtagcgt
    14401 ttaactgtgc agcaatcgtt tttaagattg ggtctactag acccactccc ataaaagcga
    14461 tcatacaggt agctgctaca actagcgctg aacttttccc ctttgtttct tcatttgttt
    14521 gttcttgtat atctatttga ttctccaata tttccatccc tttctctcta ttagcatcat
    14581 acatgattta ttttacatgt aaatatgcac atgtaaaacg tggaaacttt actgtgatat
    14641 aataaagaaa ataagacgag aggtaggatt tttatgaata ctttagccta tatattatta
    14701 tgcgtgcttt tatccaaacc acgttctggg tatgaattga agcagctgat cacaattttt
    14761 tgggaagccc atcacagtca gatctataca acgcttgcca agttagacca gcagggttat
    14821 gtgaccgttt tggacaaaga cgagcactct caaaaaaaga tctaccactt gactgatgaa
    14881 ggacgtgctc ttgtagagga atggatcaaa gaggaaactc ccgctcctac gcaaaaagat
    14941 gaatttctag caaaaatcta tgctttttcg acgctcgata aaacaacagc tactggactg
    15001 ctattcacta gagaacaaca gctgaacaaa atcatgcaaa aaaatcaaaa aaaattgaat
    15061 gacctctcgc tagacaagaa acaagaattt ggacgttatg ttgtgatcca gcgcagaatt
    15121 atgctttgtc agcaggaact ccaatggtgt cagcaagtaa gagaacaaat gcagcagttt
    15181 tttgagtaag ggataaacag aacctttcta gaaatatcta ttgaagagca aattatcttc
    15241 aataaaagag caatacagtt ggaaaagaaa aagcgatccg aacgacaggc caaaacctat
    15301 cgttcggatc actatttttc tagaactgca ttcaagagac tatgacaaaa agcatgccaa
    15361 ggcctttttt caaataacag tgttccatca ttcattactt tgaattgctt ttagcacact
    15421 tcttgaaagc gggccaacga tgatcaactg caacggtaaa gcggcaatca cattcatttt
    15481 ccaagcattc atataagcag agaataattg atcaggtatt ccttgttcca tgatcacacc
    15541 gaataaagac atacatgtca ccattcctaa aaccatcaag catgaaatag ttaagatcat
    15601 ttggaccttg ctttctggat ttactggtag tttaaaggca atttttttcg ccagcacacc
    15661 gatgatgaag acatccaaaa tgaaagccac cacgaatcca ggcactagac caatcaacaa
    15721 acttgataaa tgaagatctt gatgcagcca taaattatac gcgctcatcc ccaagaccat
    15781 caaaaaacac atcattgttg taaaaattat tccttctttt ttatttgtag gcaatctgta
    15841 ccactccttt aaatttgtca cgaaaatcat cgtagcacat ttaaaaattt ctcgtaagta
    15901 ctttttttat tttctgccct tttatttcat aaacttcatc agccgtacgc tcgacaaagt
    15961 aagaatcatg agaagtaaac aaaatcgttc ccggatatat ttgcattagc ttctctaaag
    16021 cttcgatcgt tgccatatca ataaaattag tcggttcatc taacagcaac acattacttg
    16081 gcttagtaaa aagcaaagca atcgtcagac gggtcgcttc tcccccactt aatgtacata
    16141 acggtttcgt caaagtttcc tgagcaaacc ctaagtgatt cagcaaacta cggacaagcg
    16201 attctgaaaa ctctgtttgt ctcatgacaa aacgaatgat ggattcttca gatgtcattt
    16261 gataaccctt ttgctgatat acttgaaagc ttactttcgg agagagaagg attccttctc
    16321 cttgtttgcg gatatgttct aataaggttg tcttacctga accattttca ccgacaatcg
    16381 cgattttttt acctaaagaa aactgaaaat caccatttac cagtaatgtt ctcccacttc
    16441 tttccaattg gacattttgt cccatgatgg gatagcggct gtggagttca agagattttg
    16501 gtactggaaa acggatttgt ttcatctgct gcggcttggt tgtttctcct attttttgga
    16561 gtcttctctc taatgttttc gcattctttt ggatggcttt ttgtacactg tctttttgtt
    16621 tagaggaaga caaccgatcc ggtctgattt gttgcttttt ctttttactg gacacttttt
    16681 ccaacttttc cgcttgtttt ttcttttctt ggatcgattt ttccaatcgt tttttctctt
    16741 tcatgatcga ctctgcttct cgtagctgag tctttttctc caattccttt tgagtgagat
    16801 aggcactata attccccgaa aactctcgga tttctccgtc ttttacttcc cagattttcg
    16861 atgctagctc atctagaaaa tagcgatcat gactaacaaa aaccagcgta ccataataat
    16921 aacgaagctc ttcaatcagt cgatcaatac tttttctatc tagatgggtt gttggctcgt
    16981 ctagaagcat cccttgttca taagaagaaa gaagacgtat caactcgatc tttcgttctt
    17041 cccctccgct ccatttccgc tctgaagttt cttccagtct taactggaaa tgactggcta
    17101 attccaaatt taggtccttt gcttcagcga gataggttaa ttgaggcagg tagttgaagg
    17161 tgatctctgt ttggattttc ccatgatcgg gaaaaagttc accggctatt agtttgagca
    17221 aagtcgattt accgacacca ttttctccta tgatccctat acgatcttgc tgatagacac
    17281 gaagagaatc aatagatagt tctagctggt tgccaaagct gacttgtaga tttgttatat
    17341 ttactgctaa attttccata tgttttacac tcctatttca tgtaaaacaa caattatcga
    17401 tactaaaaaa gagcagaaaa atctgtttgc aaaaaaactg catcacatct tttcctactc
    17461 tgaacgaaat aactatgact aaatcaccaa atctgtcata gctttcacct attctactgt
    17521 cgttcgaaaa aatggacata ctccatccat gaaattgttg tttatacatg tcttttgaat
    17581 ttatttagtt gttattcaaa agttcgaaac gtaatttcat cgatgcagtc atttttccga
    17641 cctccttttt tattaggtta ccacacacga ttcaaaaaaa gcaatagcta ctgaatagta
    17701 actgaaaacc ttttattcga acgtagtgat cttttctggt gctaaacgaa cagactcgta
    17761 accttcttct accgcttttc ctattgataa aataataact ggaacataac ggtctttatc
    17821 caaaccaaat gcctctgcca actgatctgc ttcgaatcca ccaattggat ttgtttcata
    17881 gccatgatca cgcgcaacta acatgaattg catagccgct aagctagaat cgactttgac
    17941 tacatcgttc atttcttctc ttgaaaaact cttgtaataa ggaatgatcg cagctaattg
    18001 ttgatctctg acttcttttg gcatcttccc tgattcgtaa gcttggttat agatttcttc
    18061 gccatattcg taacattgca tatcgccaaa aatcatgacc attgcagaag aagtatcatt
    18121 ttgtctcgta ttgaaacgga tcaaaggacg caagatttct tttgcttcct cgctttcagc
    18181 gaccacaaag cgccatggtt gcatattgac agaagaaggt gcagtcgtcg cttctttgat
    18241 catttccagc atttcttcgt gtgggatttt gtatgtttca tcatatacgc gaacggatct
    18301 tctaccagtc ataattgttg aaaaatcatt tttttgttcc attattatta acctctttcg
    18361 tttctgttgt tatattgcaa agttgggtat tcaatttatc taaaagtgtt agaaattgtt
    18421 tcatttctac atcgctgaaa gccggggata gcacggaacc tgtatcttta tggtccattt
    18481 cacaatgctc gattttcttc tgggcttttt ctgttagcgc tacatacact tcccggttgt
    18541 tctgaggatt tctctgacgc gaaacatagc catttgcttc caataccttc agatgacgag
    18601 taactgctcc ttgatcaatc tgcaactttt cttgcaaact gctttgtagc aatggatttt
    18661 cttctttcag tctcatcatg atctcgtatc tagtaagact tataccgata ttttcttcaa
    18721 agatctggac gattttttga tcggctaatt tgatttgata taaaaggtga ctaatctctt
    18781 ctaaagacat aatttcctcc tttctaataa ttgactcgtc aacgattgac ttgtcaataa
    18841 tagaataaaa aaagaaaaaa gtcaaagaat cagctgtgta ataaaaaaaa cgctctcaat
    18901 agaaaagtat agagaaaaga aattttttgt agaatgaacg gaaaaaatga taaagaaagc
    18961 acaacgctaa aaccaagatt attgattctt atcaaactat agaagatagc tcttctgcag
    19021 tagaaaattt tacaccgcca aaaatttccg aaatcgcctt ttgcaagaat cccgtcgaat
    19081 attagaaatt ggatcagtat gcttaaacag taataaaaaa gttatgacaa gatgttgtca
    19141 caaccttttt tgagtaaacg gtgttcaaaa acttgcatct gcggtaataa gttcaaccaa
    19201 acaaaaaaca tgaaaatctg tttttgtttg gctgttctta ctacttgatg cagggcagct
    19261 ttttcactac ctctttttaa taaccataaa atcctattcc ttcatatctc cagcccatcg
    19321 gtgttagcca atctctttcc ttagcactca aggtatagtg atgggtacca gttttttcat
    19381 ttggattaaa tagtcgataa attggcttgg aaccaccaga ataaaaactt agaccttcat
    19441 aacgccaacc gatttttgtt aaagagttga tctcagattg tgccattgtg taatgatggt
    19501 ctccactgta aggattgtat aaacggtaga caggttgtcc gctgtttggt gcttgccaag
    19561 caatcccttc atattcccag cctacagttg gcagataatt tttttctccg gcattcaatg
    19621 tatataaatg ttctcctgta tgacggttat acagacgata catcggagaa gttgaagttg
    19681 gtgctgtatc atactgtgtc agattatagg tttcgattac attgttcaat gtagaaccat
    19741 aattaggcgc agtggcataa cgacctgtta gccaagccgt agcatctttg taagagttcg
    19801 tattgctttt ccatgcaccg gaatagtagt aaacgcctgg ctgaaaagaa gtcgtcttca
    19861 ataccgttac gttatcttgc aatgattctt tgtacgaagg atattttcta aaagcggcat
    19921 tcaccgtaat ccattgccca ttcacatatt ccgaagtagg catcgtaaca gattggccat
    19981 tatagcttcc tttaatccca aatagattgt aattaggggc agaagccaaa gtactgttcc
    20041 cccagccact ttcaacgatg gcttgagcaa tcatgactga tgcatataag tcattggcac
    20101 ttgccaaact ttgtgcagtt gaggcaatac tatcaatgaa cgcttgttga gaattagcag
    20161 atgagcgagc ataaaaagca tagccagtat agttttcgaa ttcagacaaa tctgcttgat
    20221 gggtatgtgt caatgtttgc ccatctgtca attggttcgt gatttcttct gcattctctg
    20281 gattgttctg agcttctgct gatgtactgt cttcggtttg tgtttgttct gttgtttcag
    20341 ttgttggttc ttcggttgaa attgtatttt ctgagacagt agctgactgc aaagtactct
    20401 ctgtatcgtt ttcaattcct gtttctgaag aactcgatgt ctgagttgcg acagtttctg
    20461 tcgattcttc agctagcact gttgtgttgg caactgctag atttcctaaa agaataacgc
    20521 taaataataa attctttgct ttcatctttt ttctcctttg aattatgaaa cttttcctaa
    20581 ataacagtgt aactaaaaaa gtaaaagcaa gtcaatgtcc atatttaaat aacatttgtt
    20641 tctttttgat aaatttgctt tttctacata aaaagacgta aatgaagaat attcttctcc
    20701 attcacgcct taaattgatg gtcgtttgaa taactattta acaagtaatt ctctttggat
    20761 attatccgtt atggattata cttcctgtgt cgtcggacgg ataatcatgt tactgacaga
    20821 catccggtct ggcgtttcta tcgcaaatgc tacagcagaa gctatatctt cggaggtcaa
    20881 tccccattct ttttgcgctt catgaagttc aagagcagcc tttttgtcgc tgatggtttg
    20941 atataattca gtttgaacag ctcctggaga gatgatcgta gatttgatgt tattttgccg
    21001 ttgctcttga cgtaatcctt ccatgattgc acggacagca aattttgttc cgcaataaac
    21061 ggcggaatca ggataaacaa catgtcccgc cacagaatca gttgaaatga tatgcccaga
    21121 tttttgtttt tccatgattg gaagtacggc ggaaattcca tttaacacac ccatgatgtt
    21181 gatatcaagc atattttgcc attcatcacg gtgaccttca actaatggag cggttggcat
    21241 gattcctgca ttattgtaca atacatcgat tcgaccgaac ttttccatcg ctaaatcgat
    21301 aactgcttgg acttgtgcaa aatctcttac atctgctgtt tgaatatata gctcagcttc
    21361 tggtaaagat tcttttattg cttttaggcg atcttctcgg cgtgcagcta taactagttt
    21421 agcccctttt tctgctaata gcttcgttgt tgcttcaccg attccgcttg aagcgcccat
    21481 gatgacaatc actttttctg ataaatcatt cattctattc tcctcctgtt ttgaaaaatc
    21541 tcttgcttat actcactatc tcttatttca tcttactgtt caaataatcc gttcgacagg
    21601 tttgacgatt ttggcaggga ttcctgcaac gatggtattg tctgggacat ctttcgtaac
    21661 agttgcattc gctgcaacaa tggcattctc gccaatcgtt acgcctggca gaatagttgc
    21721 tcctgctccg atccaagcat ttttcttgat gtggattggc tttactgaca agcctcttcg
    21781 ttcttttgga tcggttagat ggttcaccgt gatgaggttg acacgaggac caatcaatac
    21841 tgaatcttct aaacagatgc cacctaagtc aacgaacatc acttgacgat tgataaagac
    21901 atttttccct atactaatat gtttgccgaa atctgtataa aaaggcagca gaacagtcac
    21961 cgtatcatct actttgtcac taatgatatt ttctagccgt ttgcggatat ctgctggttc
    22021 atggtaccca gtattcagcg ctgctaaagg ctcttcgttt tcagcttgga tctgatggat
    22081 cacttcaaag agcggatccg ttactcgaat ctctttattg acgatttgtt tttcgatgag
    22141 gcttgtcatt ttgctccctc cttttatcct tactttataa cggacggctt atcatgtcta
    22201 atacttataa aacatactta actattcctt ttaactatac ttagtggtat gcttttttaa
    22261 aaacaggagg gaaaaaatgg atattcgtat actgacgtat tttttagcag tagctagaga
    22321 aaaaaatatc agccgagcag caaaatctct gcatatcacg caacctactc tctcaaaaca
    22381 actgaaagat ttagaagaag aacttggtgt gacacttttc actcggggct cccgagagat
    22441 acagttgacg gattctggtc gatatcttta ttcaaaagga aaagaaatct tgtcgttggt
    22501 agaaaaaacg gcgaacaatt taacaaatga cgcaatcatc tctggagaaa tctacattgg
    22561 cggaggcgaa actaaagcaa tctctttcat ttctgatagc cttcattcgt tgatcaaggc
    22621 gcatcctgat atccagtttc atttatatag cgggaatgca gatgatatca tagacaaact
    22681 ggatagcgga ttacttgatt ttggactcgt aatcgaaccg acaaacaaac aaaaatacca
    22741 gtcatttcga ctgccagccc aagatcgttg gggacttttg atacatcgaa atcatccttt
    22801 agcaaagcaa accgtcatcc atccgcagga actgaaaact gttcctttga tcatttcccg
    22861 gcaaacgtca gtggacagtc aactagctga atggctaggt ttcagcatag atcagttatc
    22921 gatcgtcgga acatataact tattgtacaa tgcttctttg atggtcgata acgggacttt
    22981 tggtgcatta gctctagatg ggatcatcaa tacttatggg acggaaaaaa tattcatccc
    23041 actcgatccg ccattacaag cttcactgaa tctcatttgg aaaaaagacc agcctctttc
    23101 tcctgctgct cgtaaatttt tagatgtcct aacggagaaa tacagttaag tagagttttt
    23161 ttccttcgct ttcagctttt taacaacgaa taagataagc aaaagatcca acgattaaat
    23221 aacataagtt tcttaattta tttcttcctt ttatttctga taattccagt aaattactat
    23281 aattataaaa aaagaattga caaaacataa ctgtctatat aaaattgatt acgttaacaa
    23341 taattcgttt catgtgacta gatcatacta ggcatgaaaa atctctgagg aacatggttt
    23401 ccctaggagg tttttcgtgt ctatttttgt ttggccgcaa tcaactggtc tagcaaacgt
    23461 gaaaaccaaa tcttcaaaaa gggtgcgcgc atgaaaatca aaaagatctt taatcaaaat
    23521 gcagtattgg tagatgacgg tggacaggaa aaagtagcta ttggaaaagg gattggattt
    23581 gacagaaaaa gaaatgattt gatttttgat cgtgatgtcg aacggatatt tgtcatggaa
    23641 ccagaaggtc aaatcaagtt gcaaaattta cttaatcaga ttgatgaacg ctttttattt
    23701 gcagcagaaa cgatcattga tcatgcggaa actgttttga tggaaaagtt gaatgaacat
    23761 gtattgatcg ctttgaccga ccacattgct ttttctgcgg agaacattaa taacggtatc
    23821 gtcatccgca acaaactttt aagagaaatc gaagtgcttt acagtgatga attcagtatt
    23881 gctcaatggg cagtagagta tctgacaaaa gagcttggga ttccatatac ttatgacgaa
    23941 gcaggatata tcgcaatcca tattcacagc ggacgaagcg gtcggaacaa taaccatcgc
    24001 agtatccgtg aagtgacgat tgtatctgac atcatccatt tagtggaatc agaattggaa
    24061 acagatatcc attcagaacc attttcactg aattattcaa gactggtgaa tcatttacga
    24121 ctgcttctac aacgaaccca tgcgcaacaa tatgctgttt tagacacgga aatcgtagaa
    24181 atggtcaaac gaaaataccc agaaagctat aagatttcta aaaaaatccg tgtgttgctg
    24241 accaaagaat accagctcgc gatcacgaaa gaagaactgg gttacttggc catccatatc
    24301 gagcgtttaa gaagcgcaat cgtacaaaca aatgttaaca atcatgagga ggaaaaaaat
    24361 tgaaagcata tctacaacga atgggacgtt cccttcaact tccagttgcg gtcttacctg
    24421 ctgctgcttt actagtaggg atcggaaact ggtgggcatc ttatagtaac gacattgtcg
    24481 ctcatttttt acaagctggc ggtaacgcag ttttaggtca attacctttg ctgtttgccg
    24541 ttgggttagc actagggatg tcagtggaca aatcaggtgc tgctgccttg gcaggtttgg
    24601 tcgcatttga agttccagta aatgttttaa aaactgattc agtagctact ttattgaata
    24661 tcaaaccaga atcagttgat ccatcttttg ctcagatcag taacgtattt attggtatta
    24721 ttgccggatt gattgcggca gctctttata atcgtttcca cgaagcaaaa ttaccgatgg
    24781 ctttatcttt ctttagcggc aagcgtctag tgccaatctt ggctgccttt gtcatgttgc
    24841 tgatcagtgc agtgctactg ctcgtatggc ctccggttta ctctgcttta gtttcttttg
    24901 ctaaattcat tttgagttta ggctggggtg gtgcaggtct ttatggcttc ttcaaccgtt
    24961 tactgatccc tacaggattg catcaagcaa tgaactccgt gttctggttt gacgtagcag
    25021 gaatcaatga tattggtaaa tttttggctt ctgaaggaac aaaaggcgta acaggaatgt
    25081 atcaagctgg atttttccca atcatgatgt tcgggcttcc agcaggagca tatgctattt
    25141 acagaaatgc acgtccagaa aacaaagcaa aaacagcttc cttgatgcta gcagcagctt
    25201 ttgcttcatt ctttactggt gtgacagaac cacttgaatt ttcatttatg ttcgttgctt
    25261 ggccattata tgtcttgcat gcaattttca ctgggatttc tttagcagtg agtgcattct
    25321 tccattggac agcaggattt gcctttagtg ccggatttgt cgattacttc ctatctttga
    25381 aaaatccgat tgcgaatcag ccattgatgt tgatcgtcca aggattagta acagcagtga
    25441 tttactactt tggctttaac tttgctatca aaaaattcca tctgatgact cctggccgcg
    25501 aggaagcaga tctttcagat gacgatactg caacgactaa ttcagacaat aaatatgcgg
    25561 cacaagcaag caaaatctac gctgcattag gcggagccga caatgtaact tcgatcgata
    25621 actgtactac acgccttcgt ttgcaagtca aagatacagg cctgatcgat caaaataaaa
    25681 tcaaagccac tggcgtacct ggtatgaaga tcatcgacgg aaaaaatgcg caagtcatcg
    25741 taggtacaga agtacaattc gttgcagatg agatggcaaa actacatggt ggtgctgcag
    25801 cacgacctgc acaaacaaac accgtggtta aaacagaaac atttgccggt gaaacgatcg
    25861 aacaagatat ttacgctatc gcaaatggga aactgattcc aatcactgaa gtttcagatg
    25921 atgtattcgc ggaaaaaatg atgggtgacg gctatgctgt attaccagaa aatggagaaa
    25981 tcttctctcc aatcgctggt acgatcacaa acattttccc aacgaaacat gctgtcggaa
    26041 tccaaacaga tgctggtatc gaagtcttgc ttcatatggg catcaacact gttgacttaa
    26101 aaggcgaacc attcacttta tatgtagaag aaggtcaaaa agtcgcaaga ggtcaattga
    26161 ttgctttagt tgatcttgcc gctattcaat ctgcaggcaa aaacacggat atggtcgttg
    26221 tattcacaaa tggcgacaaa gtccaaagct tagaaatcga acccgcacgt gatgtaaaag
    26281 caaatgataa aatcggctct gtttccaaca aagcctgagc catcgtcttc cccagacttt
    26341 tttatcgata aacaaacagg agctgagaca aaaatcttgt ctcagctcct ttttccgaat
    26401 aaaaacggcg ttctcctgcc aactccgcgg taataagtcc agctaaacga aacatatgaa
    26461 gagctatttt ttatttgact cttcttatta cttgatgcag aacagctttt tcacaaaatt
    26521 tttcttcata ctcaaaacta atcggctttt tcacaacctc tttatacatt attcctgatc
    26581 caatatttct tttaatgctg cttcaagaga agttaatggt tttcccaata ctttttctaa
    26641 atcatcagag gaaatagcta actgatcctt tttaatatca tgttggatcg ctaaaaacat
    26701 gtcagctgct tcttgaggga atccggcttc ttttagattt tcgacaaacg ctgcatcact
    26761 tgcttcaata atttctaact ctttacctgt cgcacgctct aatgccttgg ctaattcttc
    26821 atagtcagtt agattgccgg ataattctaa gatttctgga gagtcacttt ctactagtac
    26881 ttttgctgca gcttctgcat attcacgttt caatgcccaa cctgtttttc catttcctgc
    26941 agcataaacg aattgaccag tttttaaagc ctgcccaatg ataggtaatt cattctctac
    27001 ataccaatta ttccgtaaaa atgtatggga aatacctgaa tccttaatca ttttttcagt
    27061 gaattggtga tctggcgcta atacactgat cgagtgatcg gcatctgcaa aacttgtata
    27121 agcgatataa gataccccag ctgcttgtgc tgccttcact acattcttat gttcggcttg
    27181 acgatttcct ggaacgccag agacaaaaag caatcgatct attcctttca acgcttcttt
    27241 cattgagtct aaatcatcat aatcaccaat acgtatatta aatccagctt ctttcagtgc
    27301 ttctcctttt tcttcactac gtactagtac atagatttca ttttgtggaa ccatcttttt
    27361 taagaattcc agcgcataac caccaaaacc tccagttgct cctgttacta aataatgcat
    27421 atttgccact ccctattctt tttatttgtt aagatttaca gctgtacatt tataaattac
    27481 acctttatca taaagagtgt ggtaagataa gtcaagcaaa aaaaatgaaa ggatgacaac
    27541 tgatgaagta ttctctgcaa tttagtgatg caatccatgt acttgcctat attgaaatgt
    27601 ttcaagatac ccgatcactt tctagtgaga tgattgccag tagtatcgaa acaaatgcag
    27661 caaatgtacg taaaatcatg agtcagctca aaaaatccgg tttgatcttt acaaaaaccg
    27721 gaaaaccgca gccttccctt gccaaaagtc cagatcagat ttctttacta gatgtctatc
    27781 gcagcatcga aggtaataca cagcttatcc aagtcgatcc aaaaacaaat ccaaattgcg
    27841 tcgttggtgc gaatatccaa gaagctttag aagaaagcta cgctcggctg cagaaaaagg
    27901 cagaagaaga aatggctaag atcacacttg atagtctgat acataaaata gccgttttgg
    27961 aaaaagaaaa aagaccagaa aacacaggcc tcgtagagag atttttataa ttctctctac
    28021 tgtgcctgca tttttctgat cggaatcgtc tacataaatt cttttattct ccgggggaca
    28081 aaagccttgt catgcccctt tttcctctct aatgctcagg tcaaagcgct gaagtcatga
    28141 cgtcttgata aacggtgttc aagtagctga ccctcggcat tagttctgaa aaatgcaaaa
    28201 tatggaaagc tatttcccat ttttcctctc taatgctcag gtcaaagcgc tactttcacg
    28261 acctctatat tatcatggtt tattgactac cggtatccag atttctccca tatatttccc
    28321 gttggtaact cccatttcga ctacagcatt tggaccccca acataggcgt aatcttctac
    28381 ttctcttaaa acatgcccaa aggccgtatt cgtcaaatca tttcttaatt cttcaggcga
    28441 ttctgctaaa gcgcttacaa caagatacgt tccttttggg aatgggatga ttcgcgtagt
    28501 gtttggaaca tcctgactcg tttgaacacc gacatagtac atcattttcc cgttataggg
    28561 ttcgttgact gtaaagaaat aatgattttc agcagcttgt ttcaatgcat ctattgttcc
    28621 attaccgata actttttgct caaatgcttg tttctctgca gccaaaccga caaaatccgt
    28681 attgctactc ttcaattcca caccaatacc cgtcaccgta aaatctggtt tttcttcgat
    28741 cctatacttt gccatttctc ccaccctttc tattatatta agttcatctt acataaaatt
    28801 aaagggaaat gacacgatta cgctcttttt tctagggata tttttatttt ttaactattt
    28861 ttttgctttc actgcaatcc aaatctcact gtaaacatta ctgaaatcct ctccccattt
    28921 tgtaaaagag atctcgggag cttcgactaa cccataatct gaagaaggaa gccattctgc
    28981 atagattttc ccccaagtat cttgtaaagt ttggggaaat ggccctttat taggaaaaat
    29041 ggcccaagtg tgttcttcta tagcaagcat ttctaaatca gcgtacggat tttcttttgt
    29101 cgtagcaaag ccaatcatgt gcatcaaact gcccttttct tccaagcggt ctccatcaaa
    29161 tccataagaa acgttgatta cttgatttgg atataaatct cctaacttat gcatctcttc
    29221 cctttgagtc tccgtgatcg tctgcgctaa cttttgtatt tcttgattga ctccttcaaa
    29281 tttgacagga acttttttcg ccacacctgc cacataaaac tgttctttct tttcgatacg
    29341 aaattccatc gattttcctc ctctgacatc aataaaaaat gtcaagcgtg gaaaagattt
    29401 ttgtatgccg tatctactga tttctgaagg cagatatcct gaccaatcac gaaaagctct
    29461 tgaaaaacct tcgactgttt catatccata tctaaacgcc gtttctgtca ctcttgatcc
    29521 atctagaaga tcgcgattag ccaaagccaa tctacggttt ttgatatagt ccattagcga
    29581 catccctgca ataaacgtaa agatgcgttt taattgatat tcagagattc ctgtattttc
    29641 ggctattatt ttataggaaa gtccttctgt caaatgttct tcgatgtaat cgatcaattg
    29701 gttcagatct ttaagcatat ttatcttcct ccttgattgc ctttttatca tattatcaaa
    29761 gaaagtcaat tacttgatga atcaggaacc aatttagtca gatgtagaaa atgttgtatg
    29821 gatctaaaga aaattctcaa gcagcgtttc gtaacggata attggtatta tctgcctatc
    29881 tatgttttac ctttagaaaa ataaattttg gggaagacag attctaagta aacaaagcgg
    29941 taaaaatatc ttttattccc ttagttaatc cgcttactac ctactgtaca aagcaaattg
    30001 ttgttcaaac tgctgatcag aacgctgctt ggatttttct ttgcgataca tcatacctct
    30061 tttatcaatt ggaacaatta tttatttcta acaaaatcac ttcatttttg tcagataaat
    30121 aaaaaacaaa aaaagttcca tctttaaaac acgctattct tttacttttt ctcacattct
    30181 ctaagaaaag aaaaggagaa tgaatttttg acaattcgag caaaagtgat tatcaaatat
    30241 gtaaaatcag ctactttttt cttaaacgtt tctttatact aaatataaat aagtgtttca
    30301 tgaaaggaga actagatgaa taattggctt gagtattttc ctgaaaacgt tttggaacgc
    30361 ggttacagct atcatctgca cggttttgtc cgtcatttga actatacaag caagtacttg
    30421 tccgcaacag tttctggcac ggaagattat aaggtagtga tcacttggga tgaaaagacc
    30481 aacatgactt gtgattgtct atatgccata gaaggaaaaa aatgcaaaca catggctgct
    30541 gtcttattcg cttacgaaga acgtccaata aaaaaatcca actactcact ttccgaactc
    30601 tcgtcccttg tttcctccgc tagttcctct cttgtacggg agcttttaac agagattctt
    30661 atagaacatc cgcactttat cgaacgcttc aaagttaaga tgccatttca tgcaataaat
    30721 tattcagata aattaacaac tatcatccat aaatacgatc atattatcaa gaaaaacaaa
    30781 aacaggaaaa cagcgaagtt catcatggag atgcgaaagt tcatccaaga agcagttgaa
    30841 tcgcttattc agcaaaatgc ctatcttccc gcattcgaat tgatcaatga agtgattgct
    30901 actctcgaaa cattctattg ggagcctgag gatgaacgaa cccttcttct gatagaggac
    30961 tgttattatt tatggaaaga attattagca gaagcacctc atgcagaaaa aaggcaaatg
    31021 ttctcttggt tcgtctgcca agtcgatcat actgacgcct cttattcaaa acgctactct
    31081 ataaaaatcc tgaaagaaga ctttcgggaa aaagaatttt ctaaccaaaa gaaaaaaata
    31141 gataaaaaac taaagaaacg gtaaagaaag acgatttcaa tgaaaaatag caagtaaacg
    31201 ataacaacca tcctaaatcc acaagaaata cagcagacct tgctttaaaa acacgaatca
    31261 tgcaaaggat gaagtaaaga agacttaacg cgtacccaat attagtcatt tgactattag
    31321 gtacgcgttt tgttttataa gtcatgacaa atttccttcg ttgctggata gattttccgg
    31381 cattgttgat agattttatg atacttttct acattttgta agagaggttc cgctgcatct
    31441 gtatattgga taaaattctg acaacaactt tcaggtgtgt cgaaccaccc taaccctagt
    31501 gcagcaatca ttgttgcgcc taatgcaggt ccttcctcca tacttaaaca atagaccgtt
    31561 gcatcgaaaa tatcagcttg gatttgtagc catgcaagat ttttcgcgcc tcctcccacc
    31621 gaaacaatac gtgtaaatct gcgacccgct agttctttac gtttcaatcc caccattgac
    31681 aaatgctcat taaaaattta gaatattcac aagtttaacg acaattatga aaatttatgt
    31741 cgtgctaaag gagttttgtt attggatgaa aagttagata taaaaactgc gatcaaagac
    31801 acgttaccta ccgttttcgg ttatatcggt attggacttg catttggtat cgttgggaaa
    31861 gctgccggat ttcatccact agtcgtcacg ttgatgtccc tgctggtcta tgctggttct
    31921 gcccaattta tcacagtcag catgcttgct agtcacagcc cattgctttc catcgttttc
    31981 tcgacctttc tagtcaattc ccgaatgatt ctgatgagta tgacgattgc tccttatttc
    32041 aagaaaaatc ggctgcttca aaatctgctg attggcacat tgctgacaga tgaaagtttc
    32101 gcactgggaa tgaataaatt gaactatact ggacaaaagt taaactttcg ttggatgaat
    32161 acagctaatt ggatttctta tttgacgtgg gtgggttctt ctcttgttgg cgcactttta
    32221 gggaatttta ttactgatcc gaaaaagttt ggtttggatt tcgccatcgt cgctatgttt
    32281 atcgggttac tttatcttca agtcatttct gatagaaaca cctctaaacg attacagttg
    32341 atcctgattg gtctcacttt gattctggta tatgtcggac tgatttttat cccaagcaac
    32401 ttagtgattg tagttgtaac actgattggg tgcggattgg gggtgtggat caaacatgcc
    32461 ttcttttgag tttacattgc tgactatttt aggttgtact ttagcaactt ggctttctag
    32521 ggtcctacca tttgtcttac tgaaaaaatt cgatttaccg caaccgttgc ttgagtattt
    32581 aagttttgtc ccgatcgtca ttatgtctgc tttatggttc agcagtctat ttacccaaaa
    32641 tatcggacat ctgccgcaga tcaatctcga aaatgctttg gcttcagttc ctacactttt
    32701 agctgctatt ctttcaaaaa gcttattggt gatcgtcttg gcaggaattc tttccctttc
    32761 gttgattcgc ttattataaa taaaaaaaca agagcttatg gcaaattact gtcatgcgct
    32821 cttgttttta tcaaagtcaa ataagaaaaa aatcggcgta ttcttgctta tccgttgaac
    32881 ggaccactaa caacgacttt tcctaacata tgtcctgttt ctacgtcttt ggttgcttgt
    32941 ttcaagttct tcgcattcat cccatctgaa tagaccttgc tcaatgtact gcggataatc
    33001 ccttcatttg ctaaagcagc aatgtgcgct aaagcttctc cttgcgtttc gatttcatag
    33061 ttatagtctg ttttagcgaa catatactcc cagtcgaagc tgatagattg gtttttccaa
    33121 acacctatat ctaacggctc tttgatccct acgatcgttc ccacatgtcc aaatggtcgg
    33181 acaaggtgct tgatttgatc aaagtagcgg gtaatatcga ataatacagc gacatactct
    33241 acttgatcga ttcctaattc acgaaaactt ttacttaagt cgtgatgata atcgattgga
    33301 tagtctacac ctgttttttt cagccattca aaattcttcg gacttgcagt cgcgtagact
    33361 tctaggccag cccaatgcgc tagttgattc aaaatcgaac cgacgccccc ggatccgttg
    33421 atcactaaga tttttttccc gcgattggca ttttcttctg gagttagacc aaatttttca
    33481 aataacaatt cataagcggt caatgaggtc aacggcaagg ctgcagcttc ttcatctgaa
    33541 agattttttg gtgcaagagc gacaatacgt tcgtcaacta gttggtattc ttgattgctt
    33601 cctgctcttg ttgttgtacc tgcgtaaaaa acgcgatcgc cgacagaaaa tttttgcact
    33661 tcgtcaccta cagcaacaac tttcccgact ccatcaaaac ctaagatacg taaagcattt
    33721 cttatcccgt tatcttggcg aagtttcgta tcgacaggat taacagatac tgcgttgact
    33781 tttaccagaa gatcccgtga actgggtaca ggtatctgtt ctttttcatc aataaagctt
    33841 tttggatcat cgatcggcaa cccttcataa aaaccgacta ccttcattaa ttccttttct
    33901 gacatacgaa ttcctcctta gcttcatcaa gttggagcat ccatacagtg ttcatttcaa
    33961 tatatatagt atgctatttg ttccaccttt tttattcatc ataattattc tcttacttaa
    34021 agtaaactat ttgcactttt ttggttaaaa aagaggttgc gacaagactt ttgtcacaac
    34081 ctcttataaa cggtgttctc ctaccaactc ttcggtcaca agtcaaaata ttcatcaaac
    34141 atgagaagct gttttttgaa attgctcctt gtgactcaga gttaaacggc aggctcacaa
    34201 cctctgatat aaacggtgtt caatcaactg accctcggta ttagctcaaa aaacgacaaa
    34261 atatgaagag ctatttttgt ttggctgttc ttattacttg atacaggaca gctttttcac
    34321 gacctctaat tcacggtgtt caagcaagaa atcattgttc actgaaaagc gttggatgtt
    34381 ctttttcaaa ggtctctaag atctctcgta cttcatcagt agatttcgta ttcatcaact
    34441 gaactcgcaa gtcatttgct cctggaaatc ctttgatata gattttaaag aaacgatgta
    34501 gtcctgtgat ggaacgcggg atgatttctg aataatgatc ttgcagatct agttgcagac
    34561 gaagtagtcc gatcagttct ttttctgtat gttccctcgg gtctttttca aatgcataag
    34621 gattcttgaa aatccctcgg ccaatcatga tgccatcaac gccatatttc tcggccaatt
    34681 cttctcctgt ctggcgatcg gggatatctc cattgatcgt gattagtgtt tgtggagcga
    34741 tttggtcacg taaagcaatg attttaggaa tgacttccca atgtgcatct actttactca
    34801 tctctttacg cgtacgcaaa tggacagaaa gattggctat atcttgatga agtaggtgac
    34861 tgatccattc ttccatctca gacatttccg tatagccgat acgcgtcttg acgctgacag
    34921 gcaaaccgcc agctttagct gcttcaatca attgtgccgc tacttctgga cgaaggatca
    34981 agccactgcc ttttccacgt tctgctacat tagggactgg gcagcccatg ttgatatcga
    35041 ttccttggaa gcccatttct gccatagcaa tgctcatttc tctaaaaaat tctggcttgt
    35101 ctccccaaat atgggcaacc atcggctgtt catcttctgt aaatgttaat cttcctcgta
    35161 cactgtcttt tccatctgga tgacagaaac tgtctgagtt tgtaaactca gtaaagaaga
    35221 catccggtgc tgctgcatgc tttacgacat ggcgaaatac aacatctgtt acatcttcca
    35281 ttggtgctaa aacaaaaaaa ggctttggca gctctttcca aaaattagta gtcatttatt
    35341 tgttactctc cattctatca agcagtgaag tcgcaatctt tctcaaaaac attgtcatta
    35401 tactaggaaa caaaaaaaga agcaaagtga acagcttaaa agatgtttct gattgagcaa
    35461 aaaaaagact gtgacaaaaa tcttatcaca gtccattttc cggaataaat ggtgttcaaa
    35521 agcttgcatt tgcggtaata agtccaacca aacgaaaaat aggaggagct atttttgttt
    35581 ggctgttctt attacttgat gcagaacagc tttttcacaa cctctccact aaacggtgtt
    35641 caatcagctg accctcggta ttcgctcaaa aaacaacaaa atatgaggaa ctattttccc
    35701 gtttgtttct ctaatactca ggtcaaaacg ctgatttcac aacctctttt ctaacttctc
    35761 aatcctcttc ctttattgat caaataccaa gtaacggcgt acaaaacaac gatgaataac
    35821 acaagtacga tcatcgatgt tgctactggc acatcgatcg ttccaaggaa tccgtaacgg
    35881 aaaccggaga tcatataaac gatcggattg acttttgaaa cagcttgcca aaagggcggt
    35941 aacatagaga tggcatagaa aacgccacct agataagtta acggctgcaa gacaaatgta
    36001 ggcacgatcg atacatcatc ataagactga gcaaaaatcc cgttgagcag tcctgctaat
    36061 gaaaacaaga ttgccgtcat caataatgta atgatgacca tgaaccatga atacacatga
    36121 agtggtacaa agaacaagga aatgatcgtt acgagagagc cgacgagaat actgcgaccc
    36181 acaccaccaa tcacaaagcc ccaaataatc acatgcgtag gaacaggtgc taccaagatt
    36241 tcttcgatat ttttctgaaa tttttgagag aagaaggacg aagaaacatt ggcatacgaa
    36301 ctagtgatag cagacatcat aatcaaacca ggaacgatga attccatata tgaaaaacca
    36361 cccatgtcac cgatccgccc accgatcatt tttccgaaaa taacaaaata caaggatgtc
    36421 gtgatcactg gcggaaccag tgtttggacc catatacgca aatagcggtt cgtttccttg
    36481 atagctaaac tttttaatgc agtaaaataa agattaaaca tttttctcct ccgtatgatt
    36541 attttcttct gtgattttca agaacagttc ttctaaacga ttcgacttat tcctcataga
    36601 aagaactttg attccttgtc ttgtaagctg atcgaagatt ccgttcaccc cttgatttcg
    36661 ttcaacttcg acagcgattg tctgctcatc ttcaaatgta caagcatatc cttcaatcac
    36721 aggtttggta tcatatggcg ctaaatcaaa gataaatgtt tcaaattgca gttttgacag
    36781 aagctctttc atacttgtat tctcgatcag ttcacccgat tggatgattc cgatgttgcg
    36841 acaaagcatt tcagcttctt ctagataatg cgtcgtcaaa atgatcgttg taccattttc
    36901 gttcaattct cgtagaaact cccacatctc gcgtctcaac tcgatgtcaa ctcctgctgt
    36961 tggttcatcc aagatcagca aacgtggttc atgcatcaat gccctagcaa tcatcagtct
    37021 tcgcttcatt cccccggaaa gcatacgtgc acggacattt ctcttttccc aaagattgga
    37081 ctgcttcaaa tatttttcgc tgcgtttcat cgcttctttg cgagagacac cgtagtagcc
    37141 tgcttgattc acgacgattt gctggaccgt ttcaaaaggg ttaaaattga actcttgtgg
    37201 aaccaatcca atctgttgct ttgctcgaac tagatccttg tccagatcat aaccgaagac
    37261 attcactttt ccagatgttt tattgactaa agaagtaata atcccgatcg ttgtagactt
    37321 cccagctcca tttggcccta atagcgcata gaaatctcct tctttcaccg aaagatcgat
    37381 tccccgcaat gcttcgaccc cacttccata gatctttttc aaattattta tttcaagcgc
    37441 atttgccatt tatttcctat ctccttatag acatgattct taattgtatc atggaataca
    37501 gcagatgaaa aaacaacttg gcttccacac aaaaacacac ctgctaacaa agaggagatg
    37561 tgttttctag ttcatgatca tcttcgatag aataactatc taaacaactc tggaactttt
    37621 aaaatcataa aagtaccgac agcaactact acgatgacat atagaagatc cttataactg
    37681 aggttcttgt cttttttatt catgttaagc tttcctccgt ccttttatcg aaagcttttt
    37741 tcttttattt taaccgaaat aaataaaatg gaaatagtta ttttcaattt ctgttttcgc
    37801 tgtttgtttt acggagaact ttgccatgga acgtgcgtct cgtcgctgat gctaagtttt
    37861 ttcgataaaa gctgctagaa ggaagacagc gtggtttatt ttgtatcgtc ttttgctaaa
    37921 tcttccaaga tcatctggac agcagactcg ttcccattga attctgccac ttttttggca
    37981 tcaatgtact tcttttgata atcgtctttt tggacccacg catcatgctt cgtttgataa
    38041 agttaatcaa acggatacca ctgacgctgt tcatcgaaca acaaactttc tttttgggcc
    38101 tgttcaacta tggatttagg ataattcaaa actttcagca aggcaatcgc atttcgggtc
    38161 cttgaaggtc cttcttttaa tttgaaatca aaactgattc cttttccttc tgttacttgt
    38221 tcttcaaagt ggacattctc acaataattc tttaaaatct ctgtcaattc gatatcatgt
    38281 gtggcgacaa atgctaaaga tggatactcc gcaagccacc gaacgactga agcggaagaa
    38341 gcaatccgtt cgatcgtatt tgttcctttt aaaatctcat ctacgaagca gtagcagcgt
    38401 tctttggaag ccacttggtc cagcaaacgt ttgatcgatt tgatttctga aacaaaataa
    38461 ctgtcgcctt caaataaatc atcttcgatt gccatggaag tcaacacatg tccaggttgc
    38521 agggtaaact gttctgcaat cgctgtttgg atcgtctgtg ctagaataca gctgatggct
    38581 atacttttga catacgtaga ttttcctgat gcattggaac ccgtgactaa tgtattcttc
    38641 tgccagttga ctggattaac taccgcttct tttaacaatg gatgatagat atctttcgct
    38701 gtcacaccgc cctcagtaaa ctctggtcgg caagtgatcg gcatataggt gcgataattc
    38761 aaaacggctg ctgcaacttc caattctccc agcaattccc acagcttgat ggcttcagtt
    38821 gaatgctttt ctaatttagt gagaacgaaa tgataggaga taaatggcag catgaacatg
    38881 atgttgacat attcaaaaat caattctgct tcactcccgc tcttcattcg aaatgaaaaa
    38941 cctaatttag ggatgtctct taatggttta gtttgctgtt tcagctcttt ttgaagtggt
    39001 gtcgtcattt ttgctaactg attggcggct gaaatcgttg aaaccaaata actcatgcta
    39061 ttcagctctg tttctagtgt ttgtttcttc actagataat agaccgtatt gaatactaag
    39121 ccaccgattg ctagatagat tcctagtact tgccctaaaa gaagcaaacc tacacccacc
    39181 agcggaagca agccaagaaa aataaataaa cctacgcgtc caatcttttt actttttcca
    39241 tccgctagat attgttttgc aaaattatga tctttttttc ctaaacgagc gaattgatat
    39301 tggattcttt ctctcagttg aggattttcc tgataaaaag caattagttt ttctaactga
    39361 taatcttctc caaaatcaaa gctacgtaaa cgctgataca acgcttctga acctacacta
    39421 gaataggtac tgttgatccc ttcaaatact tcgaacatat ccaagtcata ccaagtaaga
    39481 tcgtcgattt cactatccca tgaacggaat tttttctccg tgagccacgc atccttcaaa
    39541 ctttcttctt tatcaaatct cggttgataa ggaatttttc cccaattact acgaactgtt
    39601 tcctttactt tcaaacgtga aaaaatgtct aaaacaacta ataaaataac aactgcaata
    39661 ataattaaaa cgataaattc tctttggccc atatccctct ccgttccttg atttgttagt
    39721 tttagtatag cactgttgcg ctatttgaaa agggggtaca aaaataactg tcttcgttac
    39781 ctaattcgta tcaatcacac caaaataaaa acaccttcca aaaaagaaga tgtctttaaa
    39841 acgagataca attttttgtc attcacttca ggtaaattag agccaattaa accctccgca
    39901 acttgacgga gatggagaag atgcccccgt ctaatctagc ggtcatctct cctcccattc
    39961 cttccaccaa tttttttgac aggtaaagcc cgattccgct agattccgta tttgtgcggc
    40021 tggtattttc ggtataaaaa cgctggaaga ctttttcaac agaggtttgc gctcctggtt
    40081 tgataggatt ggccactgtt aatcgaatga atgaatcctc ttttgaaaat gtcacctttg
    40141 cttgtccatc tgcataacgc aataaattct gtatgatatt ttgcagcact cgcagcaaca
    40201 tgagcggatc tgctaataca gttgtattta tcgagtgttc agcgaacgct acctcgatat
    40261 ttttctcaga aaattgttca taaaaagaga aaaatacttc ttccacctct ttagaaaaag
    40321 aaagcgtatg gagatccatt tctttttgct tcgtctctat tcgagcaaga tcataaaact
    40381 gatccgtcat actgagtaat cttgcaacag attgtttgat gatcgttaaa tacttctccc
    40441 gtttctccgt atcctctacc tgttccagta attgtacata accgttaata gcagtcaaag
    40501 gagttctgag atcatgagaa aggccgacga tcgatagtct gatgttttct tccatttctt
    40561 gaaatgcttg tcctttttgt tcattttcat ccacccatgt attcagtgca tctactaggt
    40621 ccattagatt cttttctcga aattcgactg aaagacgacc accatattct tgtcgttcag
    40681 aaagagtggc gattttctta gttaatctct tgatttccct ttgcaggaag aaaataaaac
    40741 ttcccataaa gataacaacg agaagcaaca gccacttaat caaatctaaa ccccactccc
    40801 cacaccgtat gaatatacac agcatgtgcc tttgctagtt tccctcgaag attggaaata
    40861 tgcatattca ctgttttctc actatcaaaa tatggttctt gccaaactgt ttcataaaga
    40921 tttgctcgcg aaaatacttt tttcggatgt tctaaaaaaa gcttcagcag atcgaattct
    40981 cttcctgtca aatggacagc cacaccattc acatttacat ccctcgactc tttgtccagt
    41041 aagatttcct tgtaatagat gcgttgcgac agatctttta cttggacaga agtctgatga
    41101 cgaagttgga tgccgattcg taacaacagt tcttcgatat caaatggttt cgtcacatag
    41161 tcatccgctc ctgctgccaa caaggaaact ttatctcttt gatcgctttt tgctgaaaga
    41221 acgatgatcg gaacattcga tgtctgtcgg atttctgcta acaatgcttc acctgaaagc
    41281 cctggaagca tgagatctag aaggatcaaa tcgacaggat atgtgcttaa caataatttt
    41341 ccttccgtac ctgaataagc atcaagaagt ttgtatctct gttcaagaac ctcctccagt
    41401 aaagaatgaa cagcttcatc gtcttcgata atcaaaatag tttccagcag gaacacctac
    41461 ttaatgtcag atttttggaa aataaacatt cctagagctg atgataccac gattgttact
    41521 agactgacca gaatcatttt cggtgcttgc gaataagttg cttgttgcgc aaagtccgta
    41581 tacatgagcc acgtttccgt aaaccactcc gttagaaatt ccaagccttt gatttttgcg
    41641 aaaacaccgg gaacgaaggc cgttcccatg atataaagaa aagaaagaag caaactgaca
    41701 ctggtacttc tagtgatgaa tgtcaaagcc actggaacag ataatgtcgc taatatcagc
    41761 agaagcaata caggaaatac ttttagaaca taatttccat agtttttgat tccctcaact
    41821 tcaccaaatc cgaaagcaag tgtgtaagca atcatggcta gccccgtaat caaaaccacg
    41881 ccaagtgttg tgatcaaaag cgtaacgaga agtttcgaca cataataagt cattcgattc
    41941 cgtcctaaag ataacgtatt gcgaatcgta ccgttttgaa attcttcccc aatataaaag
    42001 cacgcaaatg ctgcgaaagc cagaagaatc catgcagcca ttttttccac cattaaaatc
    42061 cctgttgcac cgttgatgac tgtatccgtt gcttggttta attcattgcc gtattttgta
    42121 tgcatatacc attcgttcca agaataaaaa agcggaagta cgaccatcag tcctagtgag
    42181 acccacattt tacggctctt ccatactttt attttttcag cagttaatag attaaacatg
    42241 tggattgcct ccagttaatt gtaagaaata atcttccagt ttttgcccaa ctaggtggat
    42301 accatccaca ggaacttttg cctctaccaa tgcttgattg atggctgcta cttggtcaat
    42361 tccttcaaaa agctggataa cacggctaga ttggacaaaa taatccctat aaccaagaga
    42421 gtcgagaacc gttactgctt gttccgtcgc cgaagtgtca atttttataa attgacgaga
    42481 ttcttgtgcc aattcttctt tcgataattc tttgatcaag tgtccttcat gcaaaatacc
    42541 gtagtgagtg gcgatctgtg acaattcatc tagcaagtgg ctagaaagca agacggtgat
    42601 gccccgttct tttaccaaac gttggatgat ttctcgcatt tctgccatcc ctgctggatc
    42661 catcccattc gtcggttcat ccaaaatcaa aaattctgga ttcgtgatca gtgcatttgc
    42721 aatagctaaa cgctggcgca tacctaaaga gaaattcttt gctttctttt tccctgtatt
    42781 ttccaatcgc atcattttca gcaggtcttc gatttctcta tccgacacac cgccgttcgc
    42841 tgcttggata cgtaggttat ctcttgcagt taattctgga taaagagcag gggtttcaat
    42901 cgattgaccc atacgtcgtc ttgctgcctg caaatccgtc gttccaaata attcgatcga
    42961 accttcatca atcgagatca aacccataat agttctcata aaggtagact tacccgctcc
    43021 attctcccca atcaaaccat agatcattcc acgtttgatt tcgatcgata ctttatctaa
    43081 tgctttggca gcaccgtatt ttttggttat accagttgct ttcaagaccg tttcatttcc
    43141 aaaatccata cttatccttc tttcttattg ataagtgaag tatagttgac gggtataaag
    43201 aaagcagcca gaaatgtata aagaaagtgt aaattttcca attgaatttc aagaaaaatc
    43261 agactgtctc gcagacgtgg ttgagttgtc tgccaatcaa agagcgcacc aaacagtgct
    43321 aatccaagtg gactggccac catggtaatc gttgttatcg ttgacatcag acgtccttgt
    43381 atatgcgttg gaacttctcg ctgaagccag accatataaa aagcaaaaga aaacattaat
    43441 ccttaaaaac ggacttatga aaaataatac atgccgtttg ggatttacaa ttagctacca
    43501 aataagaggt tatgacaaaa gacttttcac aatcccttct tccgaataaa cggtgttctc
    43561 ctgccaactc ctcggtcaca agtcacaata tttatcaaac atgagaagca atttttgtaa
    43621 attccttctt atttcttgaa gctgaccact tctgtcacaa cctcagaagc ggataaataa
    43681 tattgtttga tgatacttta tctttttccc gtttgtttat agatcgaatg atattataga
    43741 ccaagaatcc tacctattaa catagctaaa aacacaaaaa aggcactttc caaattgtgg
    43801 aaagtgccag aaaagttagg attaaggtaa ctgcgctcag cattgcttcg cccagtacga
    43861 ttctcgtaac tcgtgaactc gaacgataat cgcaattaac gttttgagat gtgactcgta
    43921 cttattacaa gtacttctat caatagaaat ccaattatat caacattaca aacatctaaa
    43981 aaacagtttg atatggataa aataggatta atattgatat tacttgaacc aatttgaacc
    44041 aaagatgaat ggtagttgaa tacaattttc ttactagttt atcaatcttt tttagagtta
    44101 ttcctcccct cttatttatt tgagaccgta ttgatggctg gatagctgtc taataggggt
    44161 ttcaaggcca gaattagcta agctactaga ttctcgaata attgtataag ccggtcacac
    44221 ctacttaaat gtgattgaga aggtcaaata tagggtcaaa aaatactcgt cagtatgtca
    44281 gatagataaa tccaatttta cgccaaaagc agatcctttt ctcttaaaat agtaagagcc
    44341 atcgaagatt tatgtttcac ttcgcacggc ttttacttta attttccaat ttatcaaaag
    44401 gacattttac gtctttttat cttttaccga gatagatgac agttgctact taatctagca
    44461 aattcgctac acgacttttt atatcatctc taatttctct gaatttatta atgatttctt
    44521 cttctgttcc agttgctttg gctggatctt ccaaatccca atgaacatgc ttaatccctt
    44581 ttggaattac tggacattta tctttggcat cgccacatag cgtaataatt aggtctgctt
    44641 gattaaaata atccatatcg atcaaatcag atgtttgcgt agagatatct atcccttcct
    44701 cagccattac ttgaacggct ctaggattta acccatgttg ttcaatgccg gcgcttttaa
    44761 tttcaaattc atctgttggc aaaatcgctt tcccatagcc ttctgcaatt tgactacgac
    44821 aagaattgcc tgtacataaa aagtaaattt ttctcattat tatttcctcc gatatcagac
    44881 aattctgatg gattttgaat gaaccaattt ttttgtgcga ttagatattt taactaacag
    44941 taacatgact ggcacttcaa ctaagatgcc aactgccggc gcttatgtaa aaatatagat
    45001 aatcatctat gttttgtcaa atgcttctgt ctttcagttc aaattaatta gtttattatt
    45061 tgcattcgat tcaatctaat ttgaaaatca ctacttatat agatgcatcc atacaatcta
    45121 tataactcct cacatattca aattaaaatt tgattattct attaatctat gatacactac
    45181 attcaaatat ccattagaat aaaggaggag ctgtatgaaa aacgaaattt gtgaaatctc
    45241 atgtgttcat gaagataaag ttttactagg aaaagaaaag ttacaaactg aggatatttc
    45301 gagcttaaaa agtgtcttca aaattttagc tgatgagaat cgcttaaaaa ttatctacgc
    45361 cctaagttat gaggatgaat tatgtgtatg tgatatcgca gcaactatcg aggcaaccgt
    45421 ggcaacaacc tcacaccatt tattatcatt gaaaaaaaat ggaattgttg tgagtcggaa
    45481 agtagggaaa ttggtttatt actctatcaa gaatgataaa tttgtccaac tactaaattc
    45541 caaactgtat ttagaagatg aggtgctagt atgagtgaaa aaaaacaagt ctatcgggtt
    45601 gaaggattga gctgtacgaa ttgtgcggca aaattcgaaa aaaatgtttc tcaaatacca
    45661 aaagttaccg atgcaaaagt aaatttcggt gccggaaaaa tctctatcga aggcgaagcg
    45721 actattgcgg aaattgaagc tgcaggagct tttgagaatc ttaaagttca gtccgaacat
    45781 gatacagaac ctcgcattga aacaaaagag ccttttgtga aaagaaactg gaacctattg
    45841 gtttcactgt ttttaattat tttggcatta ggatctcaag tagttaacgg tgaagatgcg
    45901 ctattaacag aaggattatt tatactagcg attattatcg gcggatttag tttgtttaaa
    45961 gaaggatttt cagacctatt aaaattgaat ttctcaatgg aatctcttat gacaattgca
    46021 atcattggtg ctgcaattat tggcgagtgg actgagggct caatcgttgt tatcttattt
    46081 gcaattagcg aagctttaga acggttttca atggataaag caagacaatc aatacgttcc
    46141 ctaatggata ttgctccgaa agaagcatta attagaagaa ataatgttga acaaatgatt
    46201 aatgtttcaa aaatcgaagt aggcgatatt atgatcatta agcctggaca aaaaattgct
    46261 atggatggtc aagtcattaa aggccattcc tcagtaaatc aggctgcgat taccggtgaa
    46321 tctgtcccta ttgaaaaaaa tattaatgat gatatctttg caggaacgat taatgaagaa
    46381 ggtgcacttg aagtcaaagt tacaaagcat gtgaacgaca cgacaattgc caaaattatt
    46441 cacctagttg aagaagcaca aggtgaacga gcacctgctc aagcatttgt cgataaattt
    46501 gcgaaatatt atacacccac cattatggtg attgccgcat taatcgtcat cgttccccca
    46561 ttatttttta acggagattg gaatacttgg ttgtatcaag ggctctcttt attagttgtt
    46621 ggctgtcctt gttctttagt aatctcaaca cctgtgtcta tcgtttcagc aattggaaac
    46681 tctgctaaaa atggtgtttt ggtaaaaggc ggtatttatc ttgaagaaat tggtggcctc
    46741 aaggcgattg cctttgacaa aacaggaaca ttgactaaag gaacaccaac ggtaacagat
    46801 ttcactacag ttgattcaaa agacgaagag aaatatttct caattattac agcattagaa
    46861 tcatattctc aacaccctct cgcgtcagca atcttaaaag aagctgataa tagagcgatt
    46921 tcttataaat cagtagttgt tgacgagttt acttcaatta ctggaaaagg aatacaagga
    46981 aacattgagg ggattaccta tcttgtaggg agtccaaagc tttttgaatc tatcttaaca
    47041 gataactcaa agattattga aaattaccaa agacttcagc aacaaggaaa aacagcaatg
    47101 ctcttaggaa cagataaaca aattttagca gtcattgcag tagctgatga gttaagagaa
    47161 tcaagtaaag cagtcattga aaaattacat gatttaggaa tcgagcatac gataatgctg
    47221 actggtgata atgctacaac tgctcagtca atcggaaaac aaacaggtgt aactgaaata
    47281 aaaggcgatt tgatgcctca agataaatta gattatatta aatcacttaa ggaaacctat
    47341 ggaaaagtcg ccatggttgg tgatggtatt aatgacgcac cagcattagc tgcctcaaca
    47401 gtcggtatcg caatgggtgg cgctggaaca gatacagctt tagaaacagc tgatgtagct
    47461 ttaatgggtg atgacttaca gaaacttccc tttatagtta aattaagtcg acaaacattg
    47521 agaatcatta agcaaaatat taccttctca ttgggaatca aactattagc attattactt
    47581 gtagttccag gctggttaac gttatggatt gctatcttag ctgatatggg agcaactata
    47641 ttagttacct tgaacggctt acgactgatg aaagttaaat ctaaatagac aagtagtagc
    47701 ataaaaagag gaaagactag cgacggcagc gccgtataag ctagtctttc ctctttttaa
    47761 tgctgttgca ggacggcgta gccggactgc atgggcaagc ccctctttct aacagggggc
    47821 taacaaagaa caggaaactg tgacaactac ccatttggga gtgtcctagc agtgttttct
    47881 ttgtcacatg cttatcaatc ttgtcacctc attttgatga tggatacgct acgtttaaca
    47941 gacgttcttt ctcgacttcc atcacgaatg gtagataaag atattgttgt tctagtagat
    48001 attgattgtc ctctgtgtac tgataagaag ctgtttcttt tgaatagacc aacggggcaa
    48061 ttcgcacatc gacggtcaat tgattgatcg agtatagaag aatggctttt tcaactagtt
    48121 ccttgggcaa atgtttccca aaataggaat aggattcttg atttgctaaa tagacgagta
    48181 agcgatccac actaaagttg gaaaaggtaa agggcagaat gtgcagaatg tgattttgat
    48241 tatcatggtg taaatagagt tgagcttctt taccaaattt agttgaacca aggtaaagct
    48301 gctttttctc atcgatacat tgataagtaa attggtcttg ttccgttggt ggaatgaggt
    48361 ttataataaa aaattcaatc atccgatcca tttctttttc actaacaaga ccggcttgtt
    48421 tcagttcgtc tactattagc ccttcaatct taggatcaag cttacctgcc ttcttttgaa
    48481 gcatttctaa aatgtattgg ttttcttgag taccatacaa aagatattcg ttggtgacat
    48541 ggcctatttc tgcaatttgg tgaagggttt cggtttttgg aaggttaatc ccacgttccc
    48601 agttattgac tgtacttcgt ggtaaatcac caattagttt gccaaatttc tccatactca
    48661 actttaactc ttgacgaatc tgccgaattc gattgcccac tgcttgcttg tctatctcca
    48721 tgaaaactcc tcctcatgat aagttcttaa attcagtata cgcttgtact taaaaaaagt
    48781 caaaatgtat tgacttaaaa taaatacagg cgtacaatcg atttgtactt aaaataagtc
    48841 tgatggttct ttgacaattt aatagcagaa ggaggttttt ctatgaacca agtcaatcaa
    48901 catgatctcg gggaatcgat tcgagtttct cgagaagaaa gggggtggac ccagcgatat
    48961 ttagcagaaa aagtggggat ttcgagatcg ttattatcga aagtagaaaa aggaacgaga
    49021 caattaagtg cagaaaaatt gaatcttata ctggatagtt tgcaagaaga gatcgttcca
    49081 gttaatcgtg ttttgattga ttatctaact attcactttt tctcgaatca acatttaaag
    49141 ttgattgaag caattattgg catgcctatt gaacgctttg aggaactgga ttatgcgcca
    49201 aagggctata ttgggcaata tgtttggaat caagtaatca cgattcggta ttccattgac
    49261 gatacggtaa aaggaaccgt aatggagttt tcaggtcaag gctgtaaaca tcttgccatg
    49321 cgtttgaaga ccgcaaaatc aaactggcaa gagttcttcc gtaaggtatt agattatcag
    49381 ggaaacttta cacggattga ttttacttta gatgattttg tggggagtct cagcattcca
    49441 gaactgaagc gtaaggtaac actaggccat gtgtggacca cttttcaagt gagtgaatct
    49501 catggcggta cggatatcat aaacaatgaa tcaaatggtg agaccttgta tttaggctca
    49561 aagaagagtc agtgtcgctt ttgcttttat cagaaggatt atgaacaacg aaagcgacga
    49621 ggaatttctt tagaagaagc agaagtaaaa aatcgctttg aactacggta tcgaaaagag
    49681 aaagcgcaaa gcttggcaaa gattatttca aaaacccatg atttaaccaa actattcttt
    49741 gagttactta atggagcaat ttgtttttat gaccgtgctc caaatgatcc aggtgcaaaa
    49801 gtcgatgcca aatgggcagc ctttattggc aatcatggcg caaccaccat ttctttagaa
    49861 acaattcctc aaagctttga gaaaagtatg aattggttaa ttcacagcgt ttctcccacc
    49921 ctcgcattta ttcaagaggt agataatcat tttgattcaa atttgattaa cgagattatt
    49981 agctgtgggg aacttagttc aaggcagcaa aaaatattag aaaatttgat tgctgagcct
    50041 gattattatc aggaagaagt agaattttat atccagtgtc ttcaaaatat gaaggcagca
    50101 aaaatacaca aaaaaagcaa agcacagctt acacattaaa atgtataaac gtactccgcc
    50161 ctagacaagt tgagtatagc acatttcctt gtgtcagcca aaaaacattt ttggaaagga
    50221 aataaactat gaaaaataca ataactactt atgaattgcc ctatctactt actagagaac
    50281 aagcttctca ttttttaggg atcgatccaa aatcttttga taaattcgtt cgcgcaaacg
    50341 atgagttaga gcgttttatg ataggaagac aagaacgata cactgtcact tccctcatta
    50401 attttattaa gacgcactct atctagctaa aatatcgtag gatggttgat tagatgcttt
    50461 tcgccatgta gaatgacggt gtattcaact agcatttatc aaccatcttt cagtgaaagg
    50521 atttgttata aatgcctagt ataattaaac gtggtaactc atatagagct cagatctcac
    50581 tttacaatca tggtcaacat aagaaattga caaaatcatt tagctctaaa aaggaagcaa
    50641 ctcgttgggc cttagaaaat gaattggaga aaggaaatgg aaaacaatta gcagagcgta
    50701 caacaacatt tgctgacttc tttgaaaact ggattcatat cataaagaaa aacgatgtaa
    50761 aagaaacgac ttttcaaaat tatcaaagga cttctcaagt ggtgaagaaa ttatttggcg
    50821 atatacagtt aaaggatttg aacgatattg tagtacaacg aaaaatagat aagtatgcag
    50881 aaactcattc tcgtaaaacc actcatgaag tactattgaa aatcaaaacg gcattacgtg
    50941 atgcttatgc tcgtggctat cttgctaccg attttgcaaa tttagtcaaa acacgaggga
    51001 aagttttaga taagagaaac cgtgtacttt ctattaccga attaaagaaa ctgcgtactt
    51061 atgtcattaa tcatcgagaa aatgagttta acattcttgt actccttgcc ttagaaactg
    51121 gcatgagacg cggagagctt ttaggtatac gtcccgaaga cctctttgaa tatggtatcc
    51181 atgtcagacg ttcccttagt ccaacttctg aagatacctc gttaaaaaca aaaaattcaa
    51241 gacgagatat ttccattaat caagaagtct acgatattct aaaatctgtc ccgattaaag
    51301 ataatggata tttttttgat cctgacggct ttcaacaatc tgctaagctc gccagattac
    51361 tgaaaaaact agatattcca aaaactacct tccacggcct aagagatact catgcttctt
    51421 ttctattttc acaagatatt gatattgcct atgtatcaaa acgcttaggt catatcaata
    51481 ttcaaacaac gcagaactat tatcttgaat tgatgccaga aaaaaagcac cagcaagatg
    51541 ctgatgcttt aaacctctta aattctttgt caaatttata atttgaacca acttgaacca
    51601 aaaaattctt gtaaacgttg atacaataag gaattgatta acgttttgag aactgtgaag
    51661 ctttacgggc tttcttaaga cctggttaaa caaaactcta ttttattgca ttttacagga
    51721 atgtatttca tgcgaaatta ataagtcttt gtttatagag ttttactagg gtataaaaag
    51781 ttgtatgtta tcattacctc aaaacattac ctcagcttgg cgagttggtt gattgaagaa
    51841 taaatcattt atctagatat ctcaataaaa aatgatttct aagaaacttg tattttcgtg
    51901 ttattatttt tttgccctat caaaatttct aattcttcta gcgtaatatg attatgacac
    51961 ataatcgatt caattacttc aatacctatt tttttcgaga aagatccctt ttgttcactc
    52021 acaaaaatac tttcagaaga catatataag gaacgaagtt ttggaattag tatatcgtac
    52081 aaatagacca ccataaaatc gtccttgcaa ccattctcaa aaagaattaa atttgctgat
    52141 tgtgttacat atatcactga attacattca tggtcaattc caaaaacaat gtctacttca
    52201 ttttcttttc taattcgcgc agttacattt ttcaaacttt caccattact tataaatgct
    52261 ttagttactg taagctctga tgtttgttca gatattcctt ttataatatt ttgttcatca
    52321 gccacattcc ccataaatcc gccgattcct tttaagtaat aattctcacc taagagtcgc
    52381 ttgcattcac tgaattgata aaaaaaccag ttaaaaaaat cttctggaaa aataaattct
    52441 gatcgaactt tatttatatt tttagctcct attaatttta taactcgatt aatgttcact
    52501 tgctgcgatg aacatataac tgaataaatt gagttgttta attcaaaaaa acaactttaa
    52561 catatgcatc attaattcgt tattttttag gtagatattg atcattgtta tctctctttt
    52621 tttgcttccc atactccaac ttagaaattg ccgttataaa atttatttta aaggtgactt
    52681 tttcccctga agtatcggta gtaggaatac ttaatacctc agcttctgag gaggtatccc
    52741 aattatagtt atactttgca tcatcaccat aaagaacaat tccatttttt ttatcttgtg
    52801 ccgttagctt tactggttcg cttacttttc ttgttaatat cttggacttt acatcatcga
    52861 tattgcttat tttatcaagc ttaaataatt tacaaattaa tttcgtacta gtttttatat
    52921 ttgacgagag tgtaaaatat tttgtgtaaa tagaaaaaag gaagtccctt ctgtagaata
    52981 gagttaccac aacacattca cagaaaagag gacttccata tgaacgattt tactacagaa
    53041 attctaaaga ctctagcgaa caaaggcgat ttgaatgaat tattccgtgt ccatttggaa
    53101 aaagctgtca atacgcttct caaaacggag ttaacggctt tcctcgatta cgaaaagtac
    53161 gatcgcattg gttttaacac ggggaattct cgtaacggct cctatgaccg tacggtcaag
    53221 accgagtacg gggaacttca tctccagatt ccgcgcgacc gcaacggcga gttcaagcaa
    53281 cagactgttc ctgcttatag acggacgaat gataccttag aggagaccgt cattcacctc
    53341 ttccgaaaag gtattaccat gtcggaaatc gcagacttga ttgagaaaat gtatgggcat
    53401 cactacacgc cccaaaccat gtccaacatg actaaagtgc tgactgaaga agtaaatgca
    53461 tttaaagtta gaactctaaa tgataagtat gtcgctattt tcatggatgc tacttatatt
    53521 cctttaaaac ggcaaaccgt ctccaaagaa gcaatctata ttgccattgg tatacgagaa
    53581 gacggcacta aagaagtact aagttatgcg attgctccga ctgaatcgac ctacgtttgg
    53641 aatgagttgt tacaggacat ttactccaga ggggttcatg atgtcttact gtttattacc
    53701 gatggcttaa aaggcatgaa agatacgatt caccagattt atcctaaagc taaataccaa
    53761 cattgctgtg ttcacgtttc ccgtaatatt gctcataaag tacgtgtcaa agatcgaaaa
    53821 gaaatctgtg atgattttaa ggctgtttat caagctagct caaaggaaga ggcaaatacc
    53881 tttttaggga gtatgattga gaagtagcaa aaaacttatc ctaaagtgac gcagtcactg
    53941 ataaaaaatc aagatttatt gactttttat gagtttccgc ctggtatccg ccgaagcatt
    54001 tactcaacta atttaatcga atctttcaag aaacaaatca agaaatacag ccgcagaaaa
    54061 gagcagtttc aaaatgaaga atcactagag cgtttcctag tatccatctt tgatacatac
    54121 aatcaaaaat tcttaaatag aagccataaa ggcttccaac aagtgacgga tacattagct
    54181 tcaatgttta ctgagtaacc cattattttg cagaaggacg agttatttac acaaaattat
    54241 tgacgctccc tccaaattac ttcatcaaaa cattgatata atttttatta tatcagtatt
    54301 tattcttgat acataaatga gaaaataaat actttaaatc tattgactac aagtagtcat
    54361 taagtcttca taagatgtac aatatgacat taaaaaaata aaagcttacg accatccgtt
    54421 aaatctgaca ctaaataatg gactgctttc ttttgtatta gcaggttacg ttgactatga
    54481 atattcacca gattatttgg agaaacctct tcaacacgag aacaatgata ttaattttag
    54541 atttgtctac gagtcaaaaa gtaaaacatg gttagttgat caattaagca cgataaacac
    54601 aagcttccat gaattaccta aacctgaaaa tgaagttgag atggtcatta aaatcttcta
    54661 aaaaagaagc gttgaagggg aaatattcct ttcaacgctc ttttttatat gcttagaaac
    54721 ataaataaat tgtatacttt ctttttagcc cctattactt ttcacgaaaa atatcttttt
    54781 ttcgacgcta gcgtttctct acttctaata ctgtacacag tttttgtatt attgaaaaat
    54841 tactcattat ttagcattaa tccacatcgt tttatcaatc gaccttcata ctaaactact
    54901 ttaaagtcat cttccttctc gtttttcatt a
//
LOCUS       DAFEKH010000014        54448 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.015, whole genome shotgun sequence.
ACCESSION   DAFEKH010000014
VERSION     DAFEKH010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 54448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54448
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.015"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            12..590
                     /locus_tag="LP386_000927"
     CDS             12..590
                     /locus_tag="LP386_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918182.1"
                     /translation="MNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNT
                     MGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGI
                     YLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKE
                     LMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
     gene            complement(830..913)
                     /locus_tag="LP386_000928"
     tRNA            complement(830..913)
                     /locus_tag="LP386_000928"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(877..879),aa:Leu,seq:gag)
     gene            968..1147
                     /locus_tag="LP386_000929"
     CDS             968..1147
                     /locus_tag="LP386_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918183.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            1296..2513
                     /locus_tag="LP386_000930"
     CDS             1296..2513
                     /locus_tag="LP386_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBL1918184.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            2697..3533
                     /locus_tag="LP386_000931"
     CDS             2697..3533
                     /locus_tag="LP386_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1918185.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            3609..4757
                     /gene="nagA"
                     /locus_tag="LP386_000932"
     CDS             3609..4757
                     /gene="nagA"
                     /locus_tag="LP386_000932"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBL1918186.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            4979..6037
                     /locus_tag="LP386_000933"
     CDS             4979..6037
                     /locus_tag="LP386_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBL1918187.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            6041..7075
                     /locus_tag="LP386_000934"
     CDS             6041..7075
                     /locus_tag="LP386_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HBL1918188.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(7177..7893)
                     /locus_tag="LP386_000935"
     CDS             complement(7177..7893)
                     /locus_tag="LP386_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBL1918189.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(7862..8647)
                     /locus_tag="LP386_000936"
     CDS             complement(7862..8647)
                     /locus_tag="LP386_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HBL1918190.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(8638..9387)
                     /locus_tag="LP386_000937"
     CDS             complement(8638..9387)
                     /locus_tag="LP386_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBL1918191.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            9685..10209
                     /locus_tag="LP386_000938"
     CDS             9685..10209
                     /locus_tag="LP386_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HBL1918192.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            10225..11724
                     /locus_tag="LP386_000939"
     CDS             10225..11724
                     /locus_tag="LP386_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HBL1918193.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(11812..12414)
                     /locus_tag="LP386_000940"
     CDS             complement(11812..12414)
                     /locus_tag="LP386_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBL1918194.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            12518..13474
                     /locus_tag="LP386_000941"
     CDS             12518..13474
                     /locus_tag="LP386_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HBL1918195.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(13779..14735)
                     /locus_tag="LP386_000942"
     CDS             complement(13779..14735)
                     /locus_tag="LP386_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL1918196.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            14909..15469
                     /locus_tag="LP386_000943"
     CDS             14909..15469
                     /locus_tag="LP386_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918197.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            15462..16286
                     /locus_tag="LP386_000944"
     CDS             15462..16286
                     /locus_tag="LP386_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBL1918198.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            16296..16913
                     /locus_tag="LP386_000945"
     CDS             16296..16913
                     /locus_tag="LP386_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBL1918199.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            16931..17614
                     /locus_tag="LP386_000946"
     CDS             16931..17614
                     /locus_tag="LP386_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBL1918200.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            18297..19580
                     /locus_tag="LP386_000947"
     CDS             18297..19580
                     /locus_tag="LP386_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL1918201.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            19596..20483
                     /locus_tag="LP386_000948"
     CDS             19596..20483
                     /locus_tag="LP386_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1918202.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            20500..21336
                     /locus_tag="LP386_000949"
     CDS             20500..21336
                     /locus_tag="LP386_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL1918203.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            21339..21962
                     /locus_tag="LP386_000950"
     CDS             21339..21962
                     /locus_tag="LP386_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918204.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            21959..23250
                     /locus_tag="LP386_000951"
                     /pseudo
     CDS             21959..23250
                     /locus_tag="LP386_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
     regulatory      23609..23706
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            23822..24403
                     /locus_tag="LP386_000952"
     CDS             23822..24403
                     /locus_tag="LP386_000952"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBL1918205.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            24406..25713
                     /locus_tag="LP386_000953"
     CDS             24406..25713
                     /locus_tag="LP386_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBL1918206.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            26129..26617
                     /gene="purE"
                     /locus_tag="LP386_000954"
     CDS             26129..26617
                     /gene="purE"
                     /locus_tag="LP386_000954"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HBL1918207.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            26610..27734
                     /gene="purK"
                     /locus_tag="LP386_000955"
     CDS             26610..27734
                     /gene="purK"
                     /locus_tag="LP386_000955"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HBL1918208.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSIEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            27747..29042
                     /gene="purB"
                     /locus_tag="LP386_000956"
     CDS             27747..29042
                     /gene="purB"
                     /locus_tag="LP386_000956"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HBL1918209.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(29222..29599)
                     /locus_tag="LP386_000957"
     CDS             complement(29222..29599)
                     /locus_tag="LP386_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918210.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            29855..30583
                     /locus_tag="LP386_000958"
     CDS             29855..30583
                     /locus_tag="LP386_000958"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBL1918211.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            30583..30837
                     /gene="purS"
                     /locus_tag="LP386_000959"
     CDS             30583..30837
                     /gene="purS"
                     /locus_tag="LP386_000959"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HBL1918212.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            30839..31510
                     /gene="purQ"
                     /locus_tag="LP386_000960"
     CDS             30839..31510
                     /gene="purQ"
                     /locus_tag="LP386_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HBL1918213.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            31511..33733
                     /gene="purL"
                     /locus_tag="LP386_000961"
     CDS             31511..33733
                     /gene="purL"
                     /locus_tag="LP386_000961"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HBL1918214.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            33718..35157
                     /locus_tag="LP386_000962"
     CDS             33718..35157
                     /locus_tag="LP386_000962"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HBL1918215.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            35180..36232
                     /locus_tag="LP386_000963"
     CDS             35180..36232
                     /locus_tag="LP386_000963"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HBL1918216.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            36229..36807
                     /gene="purN"
                     /locus_tag="LP386_000964"
     CDS             36229..36807
                     /gene="purN"
                     /locus_tag="LP386_000964"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HBL1918217.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            36804..38339
                     /gene="purH"
                     /locus_tag="LP386_000965"
     CDS             36804..38339
                     /gene="purH"
                     /locus_tag="LP386_000965"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HBL1918218.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALVFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            38355..39629
                     /gene="purD"
                     /locus_tag="LP386_000966"
     CDS             38355..39629
                     /gene="purD"
                     /locus_tag="LP386_000966"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HBL1918219.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            39751..40665
                     /locus_tag="LP386_000967"
     CDS             39751..40665
                     /locus_tag="LP386_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBL1918220.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(40798..42363)
                     /locus_tag="LP386_000968"
     CDS             complement(40798..42363)
                     /locus_tag="LP386_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBL1918221.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSYFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(42356..43807)
                     /locus_tag="LP386_000969"
     CDS             complement(42356..43807)
                     /locus_tag="LP386_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBL1918222.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(43821..44837)
                     /locus_tag="LP386_000970"
     CDS             complement(43821..44837)
                     /locus_tag="LP386_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL1918223.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            45057..46145
                     /locus_tag="LP386_000971"
     CDS             45057..46145
                     /locus_tag="LP386_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HBL1918224.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            46199..47725
                     /locus_tag="LP386_000972"
     CDS             46199..47725
                     /locus_tag="LP386_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBL1918225.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            47727..48932
                     /locus_tag="LP386_000973"
     CDS             47727..48932
                     /locus_tag="LP386_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1918226.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            49189..50166
                     /gene="guaC"
                     /locus_tag="LP386_000974"
     CDS             49189..50166
                     /gene="guaC"
                     /locus_tag="LP386_000974"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HBL1918227.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFVE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            50430..51854
                     /locus_tag="LP386_000975"
     CDS             50430..51854
                     /locus_tag="LP386_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBL1918228.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            52315..53424
                     /gene="pdhA"
                     /locus_tag="LP386_000976"
     CDS             52315..53424
                     /gene="pdhA"
                     /locus_tag="LP386_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HBL1918229.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            53427..54404
                     /locus_tag="LP386_000977"
     CDS             53427..54404
                     /locus_tag="LP386_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HBL1918230.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
BASE COUNT        17402 a         9316 c        11920 g        15810 t
ORIGIN      
        1 tttttttaga catgaatatc ttatttttat tgctattttt cttaattttc cttctaacat
       61 ataggaaatg tcaaaactat tatgtgcgta tattgactgc attaccgttt ttcttaaacc
      121 tgattattta ttttggtaat acaatgggtc aaagctttac ttacgtcaat ggaaataaaa
      181 gggcaatgat ttggagtagt agtaacctga ataatctctt tacagagtta ggaacgaaac
      241 tgtcactttt ttatccaggt acttggatag ctactttagt agtcttggca ttattactat
      301 gtttaattgt tggaatttat ttaagttttg acaataagaa aacttctatt tttttagtta
      361 ttttgatgat aatgggattt tgttcaaggt taattatggg attttctccc acagtatggg
      421 cttccggaat gcggacgtac tatatacttt atgttgttat cgccatctta gtactaatgg
      481 cagttaaaga gctaatgaaa agcatgagtg tacaaaaaaa tgaatttatg caatttggat
      541 taaccgtgct tggtatttgt acctttataa taacggtgat aaacagataa tatacaaaaa
      601 atccctcgct ttagtattag gtgagggatt ttactcgttt ttcgattaat tgttttaaca
      661 cttgcaagtt tctacgagta gcttgtttcc gaccttcata tactcacctc aggctgttta
      721 catgattgta cgttcttttt gtaaaggata cagtgatatg tatataatgg cataaagaaa
      781 cgttcaaaca aaaaaactcg tgaagcaaaa ttaacttcac gagttgtagt gcagatgatg
      841 ggactcgaac ccacacgagc taacgctcac atgaccctca atcatgcttg tctgccaatt
      901 ccaacacatc tgcgtaataa taacacacta atgatagcga ggttttacat agttgtcaag
      961 ctcaaaaatg ggaggactta ttaagatgga gaaatatgac ggagaatttt caggactggg
     1021 aatgatctta ggtgtattga ttggacttgc attcggacgt tttttgcttg gttttatgct
     1081 aggaatcatt tgtggaattg caatggattg ggcagcgaat ctatggaatg actatcatga
     1141 caattaagtt ctcaacgctt gtttgtgttt ttttaatact tacgtttttc ctaaataagt
     1201 ggcaaaattt tctaggatgg agtatgatat tgaaatagta aataacaaaa aatttggaaa
     1261 gttctaactt tttgaaatga gggattggct aagtgatgag agaatttgaa aaatccaaca
     1321 aattagaagg tgtcagttac gatgttcgcg gtcccgttct agaagaagcg gagcggatgc
     1381 aagaagaggg cattagtatt ttaaaattga acacgggaaa tcccgcacct tttggatttg
     1441 aagcaccaaa cgaagtcatt cgtgatttga tcatgaatgc ccgtgactca gaaggctact
     1501 cagattccaa ggggatcttt tctgctagaa aagcaattga gcaatattgc caactgaaac
     1561 attttccgaa tgtgacgatc aatgatatct acaccggcaa cggagtgagc gaattgatca
     1621 cgatgtgtat gcaggggttg ctggacaatg gagatgaagt actggttcca atgccggact
     1681 atccgttgtg gacggcttct attgcattag ctggaggcac acctgttcat tatatttgcg
     1741 atgaagaggc agaatggtat cctgatattg atgatatcaa atcaaaaata acgagtcgga
     1801 caaaagctat tgttatcatt aatcctaata atcctactgg ggcactttat ccaaaagaat
     1861 tattagaaga aatcgttgaa gtagctcgac aaaataacct gattatttat tccgacgaaa
     1921 tctatgatcg cttagtgatg gatggtctag aacatattcc gattgctaca ttagcgcctg
     1981 atttgttcgt tgttacgctg aacggtctat ccaaatctca tcgtgtagca ggatttcgag
     2041 taggctggat ggtcctaagt ggagataagt cacacgtcaa aggctatata gaagggctga
     2101 atatgttgtc ctccatgcgt ttgtgttcca atgtattgtc tcagcaaatt atccaaaccg
     2161 cgctaggcgg ttatcaaagt gtcgatgagc tgctcctgcc aggcggaagg atctatgaac
     2221 aaagagaata tatctataat gcaatcaatg atattcctgg tctttcagcc gtaaaaccaa
     2281 aagctgcttt ttatatattc ccaaaaattg atacaaagcg attcaatatt ttggatgatg
     2341 aaaaattcgt tttggacttt ttacatgaac atcatattct acttgtacat ggtggtggat
     2401 ttaattggaa ccagccagat cattttcgaa tcgtttatct tcctaaaatg gatgatttga
     2461 aacaaacagc taagaaaatg agagaattcc tagcaaccta tcgccaaaaa tgattttaaa
     2521 aaccaaattt ttcagtagga gggccacaga caaacacact gaggctctct ttctagtgga
     2581 gttttcttaa ataactaaag tatattattt agttgcaagt cttttcttga agtttgcgac
     2641 ttcctaaagt aaaatacgaa tagaatgcga atacgcatat tttggggagg atacttatgg
     2701 aaacgttaat cgagtccttt ggaacgatca ttaaagagat tcgaaaagaa caaaaaatga
     2761 cgcaaaaaat gctttcgcat gatatttgtt cacaaagtgt attaagtcgg atcgaaaata
     2821 atgaggaact gccgaatgta ttggtgatga tgcagatttg tcaacggcta ggggtaacga
     2881 ttgatcatgt gatgaatctc tctcgaaaaa ctactcggac aaacgataaa ttatttgaac
     2941 tgttggatag ttgtttccaa aaacgtgatt atcggaagtt agaacaagta ctaaaatctt
     3001 ctgatatttc tgaaaatctg tatcaagcaa ctgactttca acgctattat tattatctcg
     3061 gtgtttgcga attcacgttg cgtcaaaata tctctcagtc cctttattat ttgaaagaag
     3121 cattaagcta ctctagccaa aaagaaagaa tccatgtttc tgacacagaa atacaactga
     3181 ttagttgtat cggaaaaata tatggtgtgg caggaaaaac ggctgaagca cgctactatt
     3241 tgagtcgaag catccaactg ctgcatcaat cagctgatga acgatcaaaa agtgaatttt
     3301 cgcaaatttt ttataattat ggaaatttct tattccatca aaatgaaatc gacgaagcgt
     3361 tagaacaggt gaatcaagga atctattggg ctcaagagaa gaatagctac tattacctca
     3421 atgatttatt tgtgcttaaa agcttaatat acaagcgtaa agaagaacca gaaagagcag
     3481 cattctatga aggcttagca caagctgtga aacaaatttc aaaaaatttg taaatggtgt
     3541 agaccattct tgacttcttc tctaaataag agtactttag aggtagaaaa acaaagggag
     3601 agaatagaat gagaactttt atctatgctg acaaattctt tttagcgtca ggtgtcaaac
     3661 atgcaggcta tcttgaaatt accgatggac tttttggtga atacaccaaa gaactacctg
     3721 agggagaagt caacatcatt gaccaaagcg gcaaatggat tgctcctggt ttggtagata
     3781 cacatattca cggctatatg aatcatgatg taatggataa tgatgcagaa ggcatcaaag
     3841 tgatgtctga aggtctgtta tcttgtggag tgacttcatt tttaccaaca acattgacgt
     3901 caagcaaaga acgtttaaaa gatgtagctg agacaatcgg caaaatgtat caggaagcac
     3961 caggagctaa aatcaaagga atctattttg aaggtccttt cttcacagaa gaacacaaag
     4021 gggcacaaaa cccaagttat ttcggggatc ctgatttgga tactttccat gaatggcaag
     4081 aagcttcagg tggtttaatc aaaaaaattg ctttagcacc ggaacgtcaa ggtgtagaag
     4141 agtttgtcaa acaagtgact gaagaaggag tagttgtttc tctaggacac agtaatgcta
     4201 cactagaaga agcgcaaaaa gctgttgaag caggcgcaag tgtatttgtc catgctttca
     4261 atggtatgcg tggattgaat catcgcgaac caggtatggt gggtgcgtta ttatctttag
     4321 aacatgtctt ttctgaattg atttgtgatg gccatcatgt acatccaaat gctgcgggaa
     4381 tcctaatgga aaaagcagga catgatcatg tcgcattaat tacagactgt atgatggccg
     4441 gtgggatgcc tgatggaaat tacaatttag gcgaatttcc agtagtagta aaagaaggaa
     4501 cagcacgtct agaatctggc aacttagctg gaagtatatt gaaattgaaa gaagcaatta
     4561 aaaatgttgt agactgggga ttagcaacac cagaacaagc agtcatgatg gctagtctga
     4621 ttccagcaat cagctgtaaa atcgatgata catgtggaaa aatcgctcaa ggacgcgatg
     4681 cagactttat cgtattgaac cctgatatga cattggaagc aacttatcta gatggcgtgg
     4741 aacgtttcca cgcataatat aatttaagtt aaccttaaaa ctaaacttct taagtttggt
     4801 tttaaggttt tttttgtgtt ctagtaaaaa tcactttaca taagtttcaa aagtttcttt
     4861 aatttcctat tgttcaataa gtaacaatgt aaagataaaa ttaaaaatgt taatacgtat
     4921 tagcaaaata aaagcttttt tttattgtga ataaatgaac ataattagga ggagaaagat
     4981 gaacttattt gacatttttc gatcgacttt gacagatatg tcgattgtca gtgcaatcac
     5041 ttcaacagtt tttattatat tattagggtt tgtttgtaga aaaaagggga ttttttctga
     5101 atctgttgga aaaattctat cgaaagtcgt cttaacagtg gctttgccag cactggcatt
     5161 tcgagctttc atgcaagata tcaatacaga attactgatg caaggaatca atgtcttgat
     5221 ttggggatta gttatttata ttattcttat tctagtttca aaaccttttt tcttaagcta
     5281 taaaggggat aagcaaacaa cgttgcgtgt cctgacgatc tttggttcta cgaccttttt
     5341 cggaacgcct atcgtcagtg cgatttatgg tcctgtcggc gtgatgtatt cctcaatttt
     5401 caatattggc taccgaatct ttttgtattc ttatggatac ataaaaatga gtggcttgaa
     5461 gatggaagct aaaaatatca aagcgatgtt cgtcaatcca atcattatcg ctacttttgc
     5521 cggccttttc atttggctgt tccaagggta tctgccacaa gtgtcagtta caggtgcaga
     5581 aggagagata agccaagtag cgtttttgcg aattgaccag actgcaccgt ggctatttca
     5641 gccgatggat tatttagctg gtttaagttc accattggcg tggctagcaa tcggcgcaac
     5701 attaggtgaa gtaagcttca aaaaagctgc atctgaaaaa acttcatggt attacagtct
     5761 agtcaaagtg gtatttgtac ctgcattgaa tatcgtgatt ctagcagttt tgacggcaac
     5821 gaatattcta ccagtcaatt ttgaagcact ggcaacaatc gttatcatga tggctacacc
     5881 agctgcaaca gtggcagcag cctatgctat cagttttgat agggaggcac ttttagcctc
     5941 caatgcatcc ttactgtcaa ctatttttgc tgtggtactg acacctgtat ggatcgttgt
     6001 attacaaatg attcatggca taggtttatt ttcataagaa atggaggaag aaagtatgag
     6061 aatcgcatgt tacggtgttc gtccgaacga gatagatttt tttgaaaaat tgaatattta
     6121 ccattatgat ctcagtcttt atgaagaact gttgacacat gacaatatcg tgtcagcaaa
     6181 ggaccatgat gctgtattgt tgaggggaaa ttgtatagca gatgagacca atcttgcaaa
     6241 aatgcaggaa tatgggattc gttatgtttt tacacggact gtgggagtca atcatatcga
     6301 tctacaagcg gcagctgatt ttggtatgac agtagcccgt gtaccatcgt attcgccaaa
     6361 tgcgatagca gagttatctt tgacttttgc catgatgctt ttgagaaata ctgcgtatac
     6421 gacgatccga acatctttca aagattttcg agtggatgag caaatgttta gtcgtgaaat
     6481 cagaaattgc acagtaggga tcataggaac aggcaggata gggttgacgg aagctgtttt
     6541 gtttaaggga ctaggagcca aagtgatcgg ctacgatatt catcagacag aagctgctaa
     6601 aaaagtattg acgttccact cgcttgaaga gttattagcc aaaagcgata ttgtcagtat
     6661 tcatgtacct catatcccag gtgaaaacga tcaaatgatc aatgaaggat ttttagctca
     6721 aatgaaaaaa ggtagcatct tgattaatac agcccgtgga gagcttcaag ataatgaagc
     6781 tattttaaga gctttgaaaa gcaatcattt agctggtttt gcaaccgatg tttttgcaaa
     6841 tgaaacagag gtttttttcc gatccttcaa gccatgggag acgattccag accctgctat
     6901 ccagcaatta gtagaaatgt accctagagt tcttgtaacc ccgcatgtag gttcaaatac
     6961 agatgaggca ttatcaaata tgatttcgac aagtttcgag aactttcgtg aaataataga
     7021 aactggaaaa acgaaaaatg aggtatctct tcctaaagcc cgtcaattaa gataagaaaa
     7081 catggatatt cgtcaataaa atgtttaaaa atagtccaag taaacagttg ttacttctgt
     7141 atacttggac tattttgtat gggataattc gatgactcaa cagtaatctg tgagcttttt
     7201 ccgcccattc tttgtcaatt cataacaggt tagcggccgg ccgatttcca aatatttgat
     7261 tctttcgttc aatatatctt gttctactaa aaaattcaaa tatttcttga cggatatacg
     7321 tgacagtgag cttttttgag ccagttcttt tgttgaaaaa atagtatctt cttttagaat
     7381 aaatgcactt atttttttta aagtcagttt tgacagacct ttaggcaaat cgatgaatga
     7441 tggtatttcg tgaatgggag tggtgtggtt gaatacttga tcgatcaatt tctgatcggc
     7501 tttttcagtc gtttggattg tctgagagaa agcaagatac ttttcgatcg ccagctgaaa
     7561 acgttgcaaa gtgaacggtt tgatcaaata atctaaggca ccgtagcgga tcacattctt
     7621 tatggtttcg atatcatctg cagcagtgat caaaatcact gggatatcat ttccttgctg
     7681 tctaagccaa gataaaaaat ggataccact ttcgccaggc atgtatacat caagcagcag
     7741 cagatctgcg tttttttgtc tgaaatattt ttttccttct tctacatttc tgaaactttc
     7801 gattacgttc atattaggga tgctttccac aaaagtacga ttcaattctg caaccattgg
     7861 atcatcttcg attatcagga catttgtcat cattttgatc ttcctttttt ggtaattcta
     7921 gatagacgat tgtaccgcca tttgtttgtt tggaaaattc taaaaatcca ccgtggcgtt
     7981 tgacgattga atggatgaga ttcaatccaa acccacgatt gattcccttc gtcgaaaaac
     8041 ctagcgtaaa tattttttct gagatttctt ctgatatccc gacaccgtca tcgcagacgg
     8101 tcacgatgaa tacttcagct tctgtgtcat agtttaaatg aatccggacc tgtccgtttc
     8161 tttcatgttt ttgtagcacg gcttcttttg cattatcaag taagttccct aacacttgca
     8221 aaagtgaatg gatggagtca tccatctcca ttttagggat aaaagaatcg ctttctaaca
     8281 gcatttcaac agattgttct ttggcttcgt ttattttgcc taataaaaaa ccggcaattg
     8341 caggtacttt gatcagactt gagacttggc caatctcttt tttataattt tgatttagct
     8401 gctggataaa atgggtgact tcttcatact tcttcaaatc aatcaaacca gaaatgacat
     8461 gaagtttatt catgaattca tgggtttgag ctctcatgga gtttatatat tgtttcgtcc
     8521 ccccaagctc ctccattaat ttcattactt ctgatcgatt tcgtaaagtt gcgactgctc
     8581 ctaaaaaacg gtcattgcta aaaagaggtg taacgctaga aatagtttct atcccattta
     8641 aatacatgga ttgagtccga acggtcgttt gatgctcaat cgtctcttta aacaaaacgt
     8701 catatagatt atcactgatt tttttcctac ttcgaaatcc aatagctgct ctgtttggta
     8761 gaaaatgttt tttgcaggtg tattgatcaa gaggatagtt ttatcagaag agatggctaa
     8821 gattccttca tctacttcat tttcgataat cgttttttca cttaactgtt ctgctatttc
     8881 ttgtggttca agtccaagca gtactttttt cattttttgg gcaagaaaaa cggcgcctat
     8941 gatgcctacg ctaagtccaa taatcaatga aaaaacaatc attttttgtc catctttgac
     9001 ttgattgtca atcgtgttgt ttgttaagcc aacacaaact gcaccaataa tctcttgatc
     9061 ataataaata gggacgaaat agcggaagcc gaaccctaac attccttctt tttcagagaa
     9121 aaattcttgt cctccaatca cttttttcac atcttcatga cttgagaaag gaagaccgat
     9181 gtaacttggg tctgcgtgag aatatcgaat gccttcaggg tccatgacaa cgataaaatc
     9241 taaattcgat gcaatcatga tttcatttgt tattccttga atcgcatgtg tcgggtcacc
     9301 agtctgcagc tttttttgga tgagtttatc attggcaacg attttagcaa tgctagagat
     9361 tttatctgac acactagatc ggttcatcga aagaataaaa ttcctgatca atatggcaga
     9421 aacaatcaaa gaaacgaatg tggagaaaca aacgacaagg atgatcgtgt tctggagctt
     9481 taatggtttt ttcttaaaaa aaggaaacat aggctacctc gaaagaattt attgtgaaaa
     9541 ttttaacatg aaaacaaaaa tttaacaaat tgtcaacgat aaacacaacc ttcctataaa
     9601 aaacaccact gagtcggtaa aagaagctat acagaatttt caaacattgg tatgatagac
     9661 gtagaaatgg aaggaggcgt gtatatgata gggggaatcg cacttgagac gatttattgg
     9721 tatacattgc tgatttgtgc aggattggca gtcctattga ttatttttgg agatgtattc
     9781 gattttgatg gcccgcttga tccgatgctt attatccctt ggttaacttt cacaagctta
     9841 tttggttttc taggtgagcg tttaacagat caatcatctt tatttttatt tattgctagt
     9901 ggaggcatat cgatagtgtt ggtatttttg cttaatttct atatattgat gccgatgaaa
     9961 catgccgaat caacgatgtc gtcttctgaa aaaactctgg aaggacaagt agctgttgtg
    10021 atcacaccga tccctgtacg aggtatggga gaaattcagt tgaaaagtgt taccggttcc
    10081 attagtcgtc cagcttgttt ttacagcccc caagaacaga cagctgagcg gggaacgaaa
    10141 gtattgatca ttgagatcaa ggaaagaatc tgttatgtca tgccttatga aagcatgata
    10201 aaagcttaaa ggagcgtgtg ttaaatggaa ataccagttg tttttatcgc gatcgcaatc
    10261 gcagctttga ttttactgat gttgctgatc gtctttgtag cgaagtacca gacagcaaaa
    10321 ccggatgaag cgttgatcat cagtggaagt tatttaggaa gcaaaaatgt gcacattgat
    10381 gaaagcaata acaaaatcaa aattgtgcgt ggaggtggcg cattcgtctt gccagttttt
    10441 caacgttcga atcggatcag tctattatcg agtaaattgg acgtctccac ccctgaagtg
    10501 tatacggaac aaggcgtacc ggtgatgtgt gatggtactt cgatcatcaa aatcggttca
    10561 tctgtagaag agattgctac agcagcagaa cagtttttag gcaagacaag agaagaactg
    10621 gaaaatgaag caagagaagt attagaagga cacttgcgct cgattcttgg ttctatgact
    10681 gtagaagaaa tctatcaaaa tcgcgataag ttcagtcaaa gcgtacaaga agtcgcttct
    10741 gtagaccttg caaaaatggg gttgatcatc gtttctttca ctatcaaaga ggtcagagac
    10801 aaaaacggtt atcttgactc tttagggaaa ccaagaatcg cccaagtcaa aagagatgca
    10861 gatatagcag aagcggaagc tctaaaagaa acgcgtatca aaaaagctca agcagaaaaa
    10921 gaatcacaag cagctgaatt acagcgacaa acagagatcg cagaatcatt aaaagaaaaa
    10981 gaactgaaat tagcaaccta caaacaagaa caagatgttg ctaaagcaaa agcagaccaa
    11041 gcctacaatt tagaaagtgc ccgagcacaa caacaagtaa tcgaacagga aatgcagatt
    11101 aaaatcgtag aacgtcaaaa acaaatcgaa ctggaagaaa aagaaatcac acgtcgtgaa
    11161 aagcaatatg attcggaagt gaagaaaaaa gcagatgccg atcggtacgc taaagaacaa
    11221 gaagcacaag ctcaaaaagt caaagaagtg actgaagccg aagcagaacg attccgtgtg
    11281 gaagcactgg cagaagcgga agccaataag acacgtttag ctggacaagc agaagccgaa
    11341 gcagcactag caaaaggaaa agcagaagcc gaagcaaaac aaaagatcgc caatgccttc
    11401 aaggaatatg gcgaagcagc tgtcttgagt atggttatcg atatgctacc gcaattgatg
    11461 cgcgaagcag cacagccgct aggaaatatc gaaaaaatct ctgttgtcga tacaggaagc
    11521 agttcaggag aaaccagtgg agcgaaccga gtgacaaatt atgccacaaa tttgctttct
    11581 tctactcaag aaacactaaa agcgacaaca ggacttgact tgaaggaaat cgtagagaat
    11641 ttgtcgacac gtgggactac tagccaagta aatatgtatg aagcgccaaa agaggcagaa
    11701 caaaactcga tgaaggaaga ataaagtagt acacttcacc gttcaatcaa aaatggagga
    11761 agacttttta aagttcttct ctccattttt ttattttatt gcaaaagaaa attagtcctc
    11821 gctatttttc ttttgttttt ggatcttagc ttctatctct tgtaaatttg ttcttagcaa
    11881 tcgttctttc ttttggagtt cgaccaaatc ttctgatagt tcttccttct tttctgtttc
    11941 aggaggacga agaaagaaat tgataccgat tgcaatgaat gtccctataa aagtatctag
    12001 tacacgttgg atagcataca aagcggattc gccttgaggg atgctcaacg caatcagcaa
    12061 caacgtagct attgcggaaa tgataccgga attattgtta ataccatctg acacgacgat
    12121 cacaataata actagaatag gaagcaagat caattctacc aaaaaatcat tgtgaaaata
    12181 gcttttgaca aaaaaataaa tgatagctaa tgtaccacct aatgtattgc cgatgatcct
    12241 agactttcca aaagaaacgg ttgtagtcaa gtcctgacgc aaagaaaaaa cagcagataa
    12301 tgcagcaatc atcgggattc ctcgttgagt caaatgaaaa aacaagatac ataaaaaaac
    12361 agctaaggca cttttgatcg tacgcatacc tagtcgaaaa cggccaaatt gcatagagat
    12421 tctccttttt ggtcttttta ctatcatacc taaacttttg tctgatagct agtttttcat
    12481 tattcaagta taattaaaat aaaaaagggg gaagtaaatg cgtataggaa tgcgaacagt
    12541 caaaacagtg atcagtgtct tcttttcgat ggtcacagcg ggtagcttat cgctgttgta
    12601 ttggccagct gcagggatca ttgcattatt aagtgtagga aataccaagc gctctacatt
    12661 gcgtacgggc atgaatcgaa tcgcagcctt tatattagct acggcaacag cactgttcag
    12721 tttttttgct gttgggtata ctatttttgg cttcagtctt tttttattcc tgttcatccc
    12781 gcttgcctct cgcttcaaat taaccgaagg gatagtagta aattcggttt tggtcactca
    12841 ttatttagtg gaggaaaaca tgtcttggca gctgatcggc aatgaagcgg gattaatggc
    12901 gattggatta gtatttgctt tgcttgcaaa tgtttacatg ccagatcgta cgaagcagct
    12961 gaaggaaaac caaatacaga tcgaaaaaga atttcgaaat attttgagac aaatggcaga
    13021 atttctttta tcagaaaata aagaagatgt gcagatcaaa tgcgaacatt tactgacatt
    13081 cattcgcgaa agccaagaag atgccagaga acatcaagaa aactactggc tcagacagcc
    13141 gctatactac gaaacttact tctctatgag aagagcacag gccaatgtga ttaaagacat
    13201 gctggaaaat ctagagagaa tccagcaacc agcttattat ggaaaacata tctatggttt
    13261 attgatttat actgcagaaa cattttcaga gtcaaatgat ggcagacaaa ttttaacacg
    13321 tattgaagaa gtttatgtat tgtatcggca aatgcctctg ccgactagtc gccctgaatt
    13381 cgaggatcga gcagaattgt tccagttttt gcagtctttt aaaagtttta ttgaaatcaa
    13441 ggcagaattc tcccaacaaa aaatccaaaa atagaggttg tgaattcagc taatattcag
    13501 gtcaaaaagc tgatttcaca acctcttctt taaacggtgt tctcctgtca actcctcggt
    13561 cacaagtcac aatattcaac aaacatgaga agctgttttt tgaaattgct ccttgtgact
    13621 cggagctgaa cggtaggctc acaacctctt tcttaaacgg tgttcaaaag ctttcctctg
    13681 cggtaataag tccagccaaa cgaaaaatag gaggagctat ttttgtttgg ctgttcttat
    13741 tacttgatgc agaacagctt tttcacaacc ttttaaaatt acatattttt ccatagaact
    13801 tgcatttgat ccaagatttc gatgacatct tttgtcaaga agagagagcg attgggcaag
    13861 tcaccttcaa tcatgtgtac catattcttt atttcgtaat tcattgcttc agatgtattc
    13921 ccgctttcga tgaattcctt tgtaccatct gtaaataaga tctccgcacg atcagcacgc
    13981 gggtaatcag caatcgtcac ataaccgttc tcaaaggcaa cgataccgac ttttggcatt
    14041 tttgcctgaa aagtcaagct gacagcagca agttcatttt ctttgttacg caagatagtg
    14101 acggattgtt cgtccacgcc tgtttcaaaa ggaaccattg tagaggcaac tacttcaggt
    14161 tgagagctca aaaagaaacg agcgaaagat acagcatacg taccgatatc caacagagct
    14221 cctccagcta attctggatt gaagaaccgg tttttagggt ctggttcttt gtaactgccg
    14281 aaaggtgctt ggatcatttt taaagccccc agttttcctg tatccattat tgagcgtaac
    14341 tgctgataaa gtggcatgtt gaagattgtc atcgcttctg ctaagatcaa attcttttct
    14401 tctgctaagc gcatagcgtc agccagttct tttttattca tcgtgatggc tttttcacat
    14461 agaacgtgtt tgcctgcttc caatgctgcc aagatatggt cgatatgctg tctatttggt
    14521 acagcaatgt acacgatgtc gatttcagca tcgtctaaca tttcttgata gcttccgtaa
    14581 gcttttggaa tattgtaacg gtgagcgaag ttttccgctt tttctgaagt tctggaagca
    14641 actgctgtta gttcgctcgt ctcttgattg aagctttcgg caaactcatg tgcgatggta
    14701 ccaagaccaa cgattcccca ttgatatttt ttcatctgaa aacgctcctt catagttgga
    14761 ttgagtttct tgtctgtcta ttattataac aaaaatcacg aagaataaag aggagaggac
    14821 ttgaaacatt aaaaaaaatg aaagcagcga tttaagaggt gctttttgat caaaacttaa
    14881 gtagaatagt taaaaggagg ggataaacgt gcatcaagta tatattgatc ttattatgag
    14941 tgtattatta gaacagtttg aaactgaaaa aaatttttta gatgaatact tgctgatcag
    15001 tccagaacaa tggcaaaaat ggaaagatgg cgagaaaaat ctgccatctg aagcgatgca
    15061 gaaagtaaaa aatcttttca ctgattatga atggatgcta acgcaaaaga ttttgcgtca
    15121 aacgattatt tttcccgaaa aacgaaacgt tgccgttgca gagtacaagc aaatcaaaac
    15181 acgcatcgcg caaaaatggc ttagcagcaa agcagcaaaa gtcgagctga tccctttgaa
    15241 aaataatcag caggctggta gataccttga cttgaaagta agtattcaat atgatgaatg
    15301 gggctatgat gatattttga attttcgtct gccagcagat gttcaaaaac agatcgaagg
    15361 agaaaaaatc gaacttctcg attgggtgaa tgaaaatctg gaagaaactt acgttcatga
    15421 ggcgaatggg gaacgtgaag aacaacgaaa ggatttttca agtgaataaa tttttaggat
    15481 ttggagcagt tgtgattatg atcgcagcaa tgggctatgt tatttttagc gatgatgatt
    15541 cgcatgttca agccggcaat caagcagtcg aacgaacaag caccaaaaca actgctagta
    15601 aagaaaagaa cagtcaaaca accagcagca aggtaaagga caaagaaaca aaagatcgta
    15661 cgtccaaaca attgccagat gttaaaacag acgattggaa gctagttttg gttggtccag
    15721 atcacaaatt agaaaaagaa attgatgagt ctactcaatt ggcatcatta agtaacggat
    15781 acttgatcga caaacgcatt gctccagaat atgaagcatt tgccaaggct gctgaagcag
    15841 ctggatttcc attagtgatg gtctcagctt accggtctgt atcatcccaa caacaagttt
    15901 tcgaacaaaa tgtccaagat gtgatgagtc gtcaaggtgt atcagaagag gaggcgacaa
    15961 agattactaa agaaacgatt acggagccag gatacagcga acaccacaca ggtctggcag
    16021 tcgatgtcgt cgatcaaaac tggtacaaca gttatccttc tactgtattg gatgcaagtt
    16081 acggagatca gcctggagct aaatggatcg cagataatgc tgcgcagtat ggatttatcg
    16141 ttcgttatcc aaaaggacac gaagatataa ctaagatcac atatgaacct tggcacttac
    16201 gttatgtcgg taaagaaaac gctgagtata tcaccaaaca ccaattgacg ctagaagaat
    16261 atctgaatga attaaatgaa aagtaggaat tgatcatggc gaaaaaaaag tggaaaaagc
    16321 aaaagcgcaa gaatatccgt tggccagcag tggttgccgg tgtagcagtg atactcttag
    16381 cctttgtttt ttccttgaag aatctgtctt ctccttttac tgataatcag caagaaaatg
    16441 aagcgcaatc ccatcagcaa tttattgaac ggcttgttcc gcatgcccaa gaactacaag
    16501 atggttatgg agtgcttcct agtatcattt taggacaagc tatattagaa tcaaattggg
    16561 gaaaaagtac cttggctagc aaatacaata atcttttcgg gatcaaggct tatggggatc
    16621 agaagaaagt aagcctggaa acaaaggaat ttgttaacga agaatggata actatccaag
    16681 gagacttcaa agtgtatgat tcatgggaac agtccatgga tgaccataca caactgttcg
    16741 tccaaggagt agattggaat cctgcgctgt atgaaaaagt gattacggcc accaactatc
    16801 aggaagccgc acaagcattg caagatgcag gttatgcgac agaccccggt tatgcgcaaa
    16861 aaatcatcca ggtcatcgag acgtatcaat tgaatcagta tgaccggaga tagcaaagga
    16921 gaagtggctg atggcagaac aatttacgcc agaaatcatg acggaattga gaaaagatat
    16981 cgtaagagta ccggaaatca ttttagaagc aagcgggatc aagatatttg gaaaattgat
    17041 ccgttcgatc atctttacta cggatattgc gatcatacgt aatacaaatg cgaatgcagt
    17101 aattgctgtg tatcctttta cacctcatcc agcgattact aaaagcatta ttgaggcagc
    17161 tgacattcca gttttctccg gtgtaggtgg tggtttgaca caaggtgctc gttcttccta
    17221 catgagcatg ttcgcagaag cgcaaggttc gttaggggtc gttttgaacg gtcctacgcc
    17281 tttagagaca gtaaaagaag tttgtcgagt agttgatatt ccagttatca gtacggtaac
    17341 gtcgaaatat acagaaatag atgaaaagtt agcagctggt atttcgatta tcaatatcag
    17401 tgcaggtaaa gaaactgcag aagcagtacg ccattttcgt aaaaaatatc ctgaacttcc
    17461 tatcattgcg acaggtggtc caacggaaga aagtattgct gagaccattc aagcaggagc
    17521 aaatgccatc acatatacgc caccaagtag cggagagctt tttagtcgta aaatggaaaa
    17581 atatcgggaa actgagaaaa agaatcatga ataacaggtg agaatcaaaa gacgaggaag
    17641 agcagatagt ggctcttcct cgtcttttgt actccagtac tatttgttca gaattcaaaa
    17701 aaaagagaaa tttttttgtt tttttacctg taatgtacat aagaagagtt aaaacctttt
    17761 gttattatta gcattctaac aaaaaaatgt cttgatttat tgaagcgctt tctatagaat
    17821 gaaaaacgaa taaaaactaa aaaaggcacc cgacaattta gtagcagcta aattgtcggg
    17881 gcttgaaaag tcagcgggaa ctgaccaatc aagttgccat agtcaatgct tgtgcatcga
    17941 cgtgtatatt gtacctaatt tcatacagaa ttactagtta tttttctgtt ttttagggaa
    18001 gagcgcacac gaagaagcat gcttatttag ctatgtcaag gatattgggc agttgtctga
    18061 tatccttttt tctttgcgta attatcctcc catcattgaa gcaagaagtg tttttagcga
    18121 tgaaagaaga atcagcacta tctaattttt cttgaaagta ttgagttgtt catcctaggc
    18181 agaacgataa ggcaagtctt ggtttttatt ccccttgaaa aagatcgttt aataaatatg
    18241 ttctgtataa aaatacagta tattgaaaaa taacaatgga agtagaggtg cagagaatga
    18301 agaaaagaat gagaatcatc ttagctttaa gtgttatgtt attcttcttg acggcttgtg
    18361 ggcaagaaga tgacaaaaaa atcacgctga acatggcttg gtggggttcg caagtccgac
    18421 acgatgcaac agtaaaagta atcgagcttt atgaagaaaa aaatccccat gtgacgatcg
    18481 attatgaatt ttatgattat gaaggatatt acacaaaatt aggtacacta gcagcatcag
    18541 atgatatctg ggacattttc caactgaaca atcaatttcc tcaatacatc aatcagattg
    18601 aaccattaga tgaatatgtg gagcaaggga taattgatat ttctaatgca gatgaatcct
    18661 atttagcaac gacgacttac gacgggcaat tagttggact gtctaacggg gtgaattcgt
    18721 ttgcgattgc ttacaataaa aatatatttg aacaattaaa tatccctgaa ccagcttcaa
    18781 attggacatg ggatgaattt gaacaaatca gctatcaaat cactgaagaa ttaggaatct
    18841 atgctatttc aagattcgaa gattttatag ctggctgtat tattcaaata ccacaagttg
    18901 agaaaggatt gaatttttat aatcgggaag atctatctaa cagcttggga tttgaaaatc
    18961 cagactatct aacagatttt ttccagctgc gtaaaaatct ggtagacaaa ggggcccatc
    19021 cagaaccagg tggtggagct gcaagtacga cggatctgtc ttttcaggcg gttagggata
    19081 gagaagcggc aatggtgttt ctatcaagta accagttgac agaaatattg tcaggggctc
    19141 ctgaagatat ggagattcag ttgattaatc cacctcgcag aaaagcagat ggagaatctg
    19201 gtatcccttt acgttcttcg caaatgctga gtatggcaaa aagctcagcc cataaagaag
    19261 aagctgctaa gtttattgat ttctttcaaa acagtgaaga agccaatgaa attttaaaag
    19321 gagaacgtgg tgtaccaatc atgtcgaata ttcgagaaca gctcgctcgt gcagatgatg
    19381 caactttgca agcgacattt gattatttag aaatgatttc cgatatggac aacggcgaag
    19441 tgaatgtctt tgatagtgct ttgaatccgg aaattcaaga ccaatacaat cttttagttg
    19501 aaaaagtcat ttatgaagaa gtaacagcag aagaagcagc agagagtctt tatgagtttg
    19561 cgtcaaacat tctaggatag cagcaggagg aaggcatgaa aaaagaaaaa ctaaaacggt
    19621 tcttggatca agacaatgtg gtcggttacg tatttgcttc tccattcatc ctaggatttc
    19681 tattgataac agtgataccg atgatcttgt cactttatta ttcgttcacc gattatcgtt
    19741 tgggaaatcc agtctcatgg atcggcttgg ataattatat aaagatgctg agtgatgccc
    19801 gttttttgaa ctccatccga gtcacttttc tctatgtatt tgcatctgta cctgtgaaac
    19861 tgatctttgg tctattgatt gcttatcttt taacgaggaa tatcaaagga acgactttct
    19921 ttcgttcttt gtattatgtg cctagtttga tcggtggcag tatttctatc gctctagttt
    19981 ggcgggagtt gttttctaaa aacgggttag tgaatatttt cctggaacga ttaggcgcac
    20041 ctgcgctttc ctggtttagc gatcaaaaac tggtcatgat ccctcttgtt ttgatgtctg
    20101 cttggcaatt cggttcggca atgatcatct ttgctgcagg tatcaaagag atcccaggct
    20161 cgtattatga agcggcagag atcgatggag cgaacaaatg gcagacgttt tacaagatca
    20221 cgttacctct tctttcgccg atcattttgt ataacttggt tatgcagaca atcgcggcgt
    20281 ttatgacttt tacgcaggca tttatcatta cccaaggtgg tccgaatgat gccacgaact
    20341 tttatgctct ttatgtgtat aaccaagctt tttcttttaa ttctatgggg tatgctagtg
    20401 ctatttcgtg gatcatgctg ttgattatgg gagctgtcac ctttctgatt ttcaaatcat
    20461 caaaaaaatg ggtcgttgtg tgaatgagag gaggaagaaa tgaataatac agtaacgaaa
    20521 tggtttcaat acggttttat tttgctatta ggtctagtca tgatttatcc ggtcttatgg
    20581 atgatcgcag gttcttttaa aacggatcaa gagattatga gtggttcgct gaatttgatt
    20641 ccagagactt ttcaatggga aaattacgca aaaggatggg cggggtttgc tggaatttca
    20701 ttttttactt tctttaggaa ttcgtttgtc atctctgcag tttcgacgat agggacagtt
    20761 ctgagctcga cttgtattgc ttacgcatta tcgagaatcg atttcaaagg aaaaagattc
    20821 tggttcgtcg tcatgttagt aacgatgatg attcctgcac aagtgatttt gattccgcag
    20881 tttattattt acaatcggct gaatttggtt gggacgtatg tgccgctgat tttaccacat
    20941 ttttttggac aagcattttt catttaccag atcatgcaat tcatggtcag catccccaaa
    21001 gagttagatg aatcagcgat tattgacgga tgcagcaagt atagtgtctt taccaaaatt
    21061 atttttcctt tgctgaaacc ttcgatcatc acgacgatca tcatccagtt ttattggaaa
    21121 tgggacgact tcatgggacc attgatttat ttaaacaagc cgagatctta cacggtatcg
    21181 attgccatca aattatttgc agacgctgga tctagtacga cttacgcgag tatgtttgcg
    21241 atgtctacgt tgtcgctgct accggttttt ctgattttct tattcttcaa taaatatctt
    21301 gtccagggga tcagtacaag cggtctgaag ggctgaatat gaaaaagcca atagaagaga
    21361 tgtttcttta caagctcaac tactatgtct gtcggatttt tttaaccagt cttatcagta
    21421 atgctctttt cgctttagtt ctaggatgtt tgttcacttt aggattagtg ctgtctgctc
    21481 gtgttgtcta tctgatttat tttttgatga tgtatccttc ttattatcta tctgtccatt
    21541 acttggcaga aaaaaaggta tgttggagga aaggaaaaat caaacggatg tgtttcatca
    21601 ttacgttgtt tcagctgttt gtcattattt ttgcagttga ttggtattta ttagtgggaa
    21661 agattggagc ttggtatctg attccttttc tattgtgtct gttgcttttt gtatcccata
    21721 gtttttttag tacgctaatt gatatctgca aagaagataa agcagatagt cttgtttatt
    21781 tgatcaaaag gaatatctgg ctgttgtcaa aaaacgtcaa ggggtttctg tggtatttat
    21841 gccttttgta tggactgttc tggtgtatac agcatgattt tttactcact gcattactgt
    21901 atccagggct gccatttgtc acagtatttt gcttaaaaga aaaggagaat gactttaaat
    21961 gaagaaaaaa tatgtacaag tcggacttgg tgggagagcg cgtttttttt atgaggcaat
    22021 tgcctctacg tatcatcaaa cttgtgaact agtcggtttt tgtgatgtat ctcaaacaag
    22081 gatggattat gcaaatcgga tacttgtgaa caagtatgga cagaaaaaag taaagacatg
    22141 tatgccatca caatttgagc aactactgga tgacgtacgg ccggctgaag tcattattac
    22201 gtcagtagat cgaacgcatc atgattatat cattcgtgca atgaaaaaag gatatgatgt
    22261 tatttgcgaa aaacctctga ctatcgatga ggaaaaagct caagaaataa taacggtcca
    22321 aaaacagacg ggaagaagcc tgcgagtcac ttttaattat cgttatgcac cgtatcacac
    22381 gaagataaag gaactgatag aaagtgatgt gattggtgat gtgttttcta tccacttcga
    22441 atggctgtta aatacgcaac acggggcaga ttatttcaga agatgcatcg aaataagcac
    22501 aatagcggcg ggcttcttgt tcataaatct acccatcatt ttgatctagt gaatttttgg
    22561 ttgaacagcc gtccccaaaa ggtatttgca ttcggtggat taaactttta tgggatgcat
    22621 aatgcggaga aacgcggagt agaaatattt tacagtcgat gctatggaag cgaactagct
    22681 aaagctgatc catttgctat agacctgtca gccaatgagg aattgcgaga aatgtattta
    22741 gaagcagaaa aagacagtgg atatattcgt gaccgcagtg tattttccga tgatatctct
    22801 attgaagata cactaggcgt aacggtcaaa tatgaaactg gtgcgatttt gacgtattcg
    22861 ctaaacgcgt atatgccgtg ggaaggattc aatgtttctt tcaatggcag caaaggacgg
    22921 atcgaaatga aagtgatcga aaagtcttac atcaatgcag gtggagataa aaaggatgaa
    22981 ggagcagccg ttcttcagtc catccatgtc tatccgatgt tcggtgagcc atatgaggta
    23041 atcgtcgaac aagaagcggg cggacatggc ggaggagatc cgcgtttatt agatgatcta
    23101 tttggtgaag aaaaagaaga agatccgtgg aatcgggcag caactcacgt agatggtatt
    23161 ttgtcgattt tgacaggaat cgcagcaaat cattctattg cttcaggaaa agcagtagtg
    23221 attgacgagc ttgtcagctt aaaagaataa gaatagattt acggaaatta cttcccgtag
    23281 tttataaaat cttgccttat tgccgatagg ctgtcttttg aacactattt attcggaaaa
    23341 aggggctatg acatgctttt tgtcatgcct tctttttatg tgggctgctt ttttagatag
    23401 gagaaaataa aaataactat ttaaacccga acaaaaagga ataatgcatt aaaaatcatt
    23461 agattttaca aaaaaataag taaaccacgt tgtcagtttc agaaagtagt gttagactgt
    23521 tttcaatatt tgaaacaaca ttttttattc aaatatggca aactgccttc acgtgcaaaa
    23581 cagttgcaag aaaatgaatt tacactatta ttagttttac atacctactt atatatcgtc
    23641 ataatatgga tgacagtttc tagccagtac cgtaaatgct ggactataag taaaagattg
    23701 gctatttcac ccttcttttc ttatgataaa gtggagggtg tttttcttta acagaaacat
    23761 agtaggtttt tgcacaaaag cggttatttc ggtattaata aatgataaag gagcaaataa
    23821 agtgaaagaa ttagttgaac gtattcaaaa agacggacgt atattaggcg agggcgtatt
    23881 aaaagtcgac agcttcgtca ctcaccaagt agaccctgta ttgatggaac aaatgggaaa
    23941 acggtttgca gaagtattta aagaacaagg aatcacgaaa gttgtgacca ttgaagcttc
    24001 tgggatcgca ccagctttat ttgctgcaag agaattagat gttccaatga tcttcgctag
    24061 aaaagcaaaa agtttgacga tggatgaaga attattgaca gcttctgttt attcttttac
    24121 gaaacaagtg acaagtacga tttctatttc tcgtaaattt ttatcttcag aagacaaagt
    24181 attgattatc gacgatttct tggcaaacgg acaagcggca aaaggattga tcgaattatg
    24241 ccagcaagct ggagcgcaag tagaaggaat cgggatcgtc atcgaaaagt ctttccaaga
    24301 tggacgtcag ttacttgaag aaatgggatt gagagtcgtt tctcttgcgc gtattgcttc
    24361 cttgacgaat ggacaagttg agtttcttga ggaggacgca taatcgtgga aaaagaaaca
    24421 caaaatggaa aagctgcggt tttagggctg cagcatctgc tagcgatgta tgcaggagca
    24481 gtagcggtgc ctcttttgat cggtacagga ctaggcttta atcaagaaca gatgacttat
    24541 ttgatttcaa ttgatatctt tatgtgtgga ttagcgacat tattgcaatt gacagttaac
    24601 cgatttttcg gaattggctt gcctgtcgtt ttaggatgtg cgatccaagc agtagctcca
    24661 ctgatcttga tcggaaccaa tgaaggagta ggagctatct acggatctat tatcgcttct
    24721 gggatctttg ttgtgttagt ttctggtgtc ttttctaaaa ttaaaaaact attccctcct
    24781 atagtaacag gaacggttat caccgttatt ggtttgactt tgattcctgt agcaatcgag
    24841 aaaatgggtg gaggtaatgc aacagcagct gattttggtg acaaaacaaa tctgctactt
    24901 gcatttgtga cgattctcct aattgtaggc gtgcaaatgc tggcaaaagg gttcattcgt
    24961 tcaatcgcgg tattgattgg tttagtcgga ggaagcatct tagctgcttt catgggaatg
    25021 attgatctga gcgcgattgg agatgcgccg ttgttccatg ttccacaacc cttttatttt
    25081 ggtaaaccaa ctttcgacgt atggtcgatt ttactaatga tcatcatttc catggtcagc
    25141 atggtagaat caacaggtgt atattttgca cttggtgaca ttactgggaa aaatgttgga
    25201 gaagaagaat tgaaaaaggg atatcgtgca gaaggacttg ccgttatctt aggcggtatt
    25261 ttcaatacat tcccttatac tggcttttct caaaatgtcg gattggttca actttcggga
    25321 atcaaaacaa gaaaacccat ctatttctct gcattcttct tgattgtttt aggattattc
    25381 cctaaaatcg gtgcgttagc acaaatcatc cctgagccgg tacttggtgg aggaatgtta
    25441 gtcatgttcg ggatggtggc agtccaagga atccgtatgc tgttggaagt tgatttcagc
    25501 aatgataaaa atctattgat tgttgctgtt tctgttggat ttgggctggg tttcaatgtt
    25561 acgccgacat tattcagtca aatgccgcaa acattgcaaa tgttcactgg aaatggcatc
    25621 gtaatgagta gcattacggc tatcatattg aatttgatct ttaatggatt gaaaaaagat
    25681 gaagaaatat tggaagaagc cttcaagaag taatagagca aaagaaaggt tgtgaaatca
    25741 gcgttttgac ctgattgtta gagaaacaaa cggaaaaata gttcctcgta ttttgccgtt
    25801 tgtttgagct aataccgagg gtcagctgat tgaacaccgt tgaaggaaga ggtcgtgagc
    25861 ctgccgttca tctccgagtc acaaggaaca atttcaaaaa aaagcttctc atgtttgttg
    25921 aatattgttc cttgtgaccg aggagttggc aggagaacac cgtttatcca taaaaaggaa
    25981 tgtgacctaa cttttgtcac attccttttt tttatcttta ataaacacga acaataaaat
    26041 gtttttcttt gttaacattc gaaatttctt tgacatcaaa aaaagtgatt gttaaaatat
    26101 gaatgtagaa aaactgggag gaaaaacaat gacagcaaaa atctctgtga ttatggggag
    26161 tacttcagat tgggaaacaa tgaaagaagc atgtcaaata ttggatgaat tcggtgtgtc
    26221 ttatgaaaaa aaggtcgttt ctgctcatcg aaccccagat ttgatgtttg aatatgcaca
    26281 aaacgctcga aaaaaaggaa tcaaaatcat tattgcagga gcagggggag ccgcgcatct
    26341 gccgggtatg gtcgcatcaa aaacaacttt gccggttatc ggtgtaccgg tccaatcacg
    26401 aacattaaat ggtttggatt cgcttctttc gattgtccaa atgcctggag gagtacctgt
    26461 agctactaca gcaatcggaa aagcgggagc aattaatgct ggactacttg cgatacagat
    26521 gctttccatg tatgatttag aattggaggc taaattggct gaaagacgtt caatgttggc
    26581 taaaactgtt atagaaagta gtgatcaact tggttaaacc tttgttgcct ggttcaacga
    26641 tcgggatcgt cggtggcggt caattaggtc gtatgatggc gattagtgca aaagaaatgg
    26701 gctttaaagt aggtgtgctg gatcctgtga gcgattgtcc agccgcacaa gttgcagatt
    26761 ggcacattga aagtgtctat gatgacacct ttgcgctgaa agagcttgcc agaagaacag
    26821 atgtcattac ctatgaattc gaaaacgtca gtatagaggc gttaaatgcg attttaccca
    26881 tgtcatttat tcctcaaggg acagacttgc ttgcgattac gcaagaccgc ctgttagaaa
    26941 aatctttttt ggaaacgaat aacatcgtga ttgctcctta tgcaacgatc gtcagtccga
    27001 cggatatcca agatgcgatt gacgggatcg gctatccttg tgttttgaaa accactcgag
    27061 gcggctatga tggcaagggg cagtatgttt tgaaaagtcg ggcggatcta gctcctgcca
    27121 tggacctttt aagagaagga acctgtgttt tagaagcatg gatcccgttt gaaaaagaga
    27181 tttcgatcat ggtggcagga aatggtcaag gagatttcac gacttttccg gtcgtggaaa
    27241 acatccacca caacaatatt cttcatgaaa cgattgctcc agccgcgatt gatcaggatg
    27301 tgatcgagga ggctgagcgt attgcccgtg tgattgcaga agcagtgagc ctttcaggtg
    27361 ttttaggggt agaaatgttt ttaacaaaaa caggcgggct atatgtgaat gaattagctc
    27421 ctcgtcctca caattctgga cattattcta ttgaagcttg ttctatgagt cagttcgatg
    27481 cccatattcg aggtatttgt ggttggccat taggagaaaa agtacgtttg ataagcaatg
    27541 cagtaatggt caatgttttg ggagaacaac tgctggaaag ctatcgcttg attgagaata
    27601 agccagactg gcaattccat ttctatggaa aaaaacaagc aaaaaaaggt cgcaagatgg
    27661 gacatatcac tatcttgaca gaagacatcc agcaaacgct ggaagaaatc aaacaaacga
    27721 atatttggga ttagaggaga aaaaacatgt tagaacgtta tacacgccct gaaatgggga
    27781 atatctggac ggaagagaac aaataccgtg cgtggctcga agtcgagatt ttagcagatg
    27841 aagcttgggc agaacttggt gaaatcccgc aagaagatgt gaaaaaaatt cgtgagcatg
    27901 catcatttga tatcgatcgg atcttggaaa tcgaaaaatt aacacgccat gatgtcgttg
    27961 cgtttacacg agcggtttct gaaacattgg gagaagaaag aaaatgggtc cattatggtc
    28021 taacaagtac ggatgtcgta gatactgctt atggctatct catcaagcaa gcaaatgata
    28081 ttttacggga agacttgaaa cgttttacgg aaatcattgg cgaaaaagca aaagaacaca
    28141 aatatacagt gatgatgggt cggacacacg gtgtccatgc tgaaccaact acttttggat
    28201 tgaaacttgc cacatggtat tcagaaatga aacggaacat cgaacgattt gaacatgcgg
    28261 caaaaggagt agaagcagga aaaatctcag gagcagtggg aacgttcgca aatatcccgc
    28321 catttattga agagtatgta tgtaaacaat tggggatccg tccacaagaa atttctactc
    28381 aagttctccc tcgggatcta catgctgaat atttctcagc gatggcgctt attgctacaa
    28441 gtattgaacg ttttgcaaca gagatacgcg gattgcaaaa atccgaaaca cgtgaagtag
    28501 aagaattttt tgcgaaaggt caaaaaggtt cttctgctat gccgcacaaa aggaatccga
    28561 tcggttcaga aaatatggct ggtctagcca gagtggtgcg cggacacatg gtcactgcct
    28621 atgaaaatgt cacattatgg catgaaagag atatttctca ttcttcagca gaacgaatca
    28681 tcttgcctga taccacgatt ttattgaatt acatgttaaa tcgttttggc aatatcgtta
    28741 aaaatctaac ggtctttcct gaaaacatga agcggaatat gtctgcaaca tttggtttga
    28801 tttatagcca gcgcgttatg ctgaaattga tcgataaggg aatgacaaga gaagaagctt
    28861 atgatcttgt tcagccaaaa actgcgtacg cttgggacaa ccaagtgcag ttccgcccgc
    28921 tgttagaaga agatccaacc atcacatcgg tattatctaa agaagaaata gacgatgcct
    28981 ttgattatca tcatcatttg aaaaacgttg acgtgatatt caaacgagta ggtttggaat
    29041 aaagaagagt gagttgcaaa attcaattaa aatagaatag caaaaataac caaaaaagaa
    29101 gcagatccgt tagcggttct gcttctttta gtttattata ttttcttatc aataatagga
    29161 acctgatttt aaaagcggct acctctttac cgtgcctctt tacatacaaa aaatagagga
    29221 attaagcgta aatggcttgg ctattataac taaaatgctg gttatggaga tgttgcagca
    29281 agttttcgag aaaagcgtat tccatctctt gtccattgaa taagatctgg atacgataat
    29341 gatttttgaa acgcttctgt tcatgaatct gactgattga aagttcgcct ttgtgttctg
    29401 tctgataaag aaaagtcctt ttacggcatt cagcacagcg cttggttgct cggcggattt
    29461 ttcggaatgt ataaaaacta gtatctttat tgcataaata aacgtctttg atcgacagca
    29521 aatcattata tagacaggaa cgttcttcag ctgttaattc tgataaaaaa agctgacctt
    29581 gttttattgc atcttccatc ggcaagtgcc tcctcgaacc cattatccaa atttttagtt
    29641 aattctaata taccatcatt aagtataaat gtaaacgctt gttgatggta taagattttc
    29701 gtttctgata aaacacgaac attaaaagaa tctaatgcct taaatgtaca tatttttgtt
    29761 gatttataaa aagatgattg ctaaaattta aagtgaaaaa acgaacaaaa aacgatgtat
    29821 ttgcttttaa tgtaaataaa aaggagagac gtacatggag aagaaagaac ttttgtatga
    29881 aggaaaagcc aaaaaaatat atcttacttc tgatgagaac ttgatttgga tagaatattt
    29941 agatcaagca actgcgttga atggcgcgag gaaagaccag ataagtggaa aaggagaatt
    30001 gaataatcaa atcacaagtg caattttccg ttatctgact caaagaggaa taaaaaatca
    30061 ttttattgaa caattgtcta aaaccgaaca attagcaaaa aaagtacaaa ttatccctct
    30121 ggaagtggtt atccgaaata ttgcagcagg aagtttctca aaacgtctag gtgttcccga
    30181 aggtaaagaa ttcatcaaac caatcattga attctactat aaggatgacc agttggatga
    30241 tccatttatc aatgaagagc atatctattt cttacaactt gcaaagccgg aagaaatcag
    30301 tgagctgaaa gcccaagcgt tggctattaa tgaaattttg accgaattat ttgctaaggt
    30361 cggtttggtt ttagtagatt tcaagctaga atttggccgg tcgaatggac aaattttgct
    30421 tgcggatgaa gtaacaccgg atacttgccg attatgggat gaacgtacga atgaacatat
    30481 ggacaaagac gtttaccgca gagatctagg tgatttgatc ccagtctatc aagaagtata
    30541 taaccgtcta tcggaactaa ctgaagaaaa ggagcgagta tgatgtattt cgtaaaagta
    30601 tatgtaacct ataaagattc agtgttagat cctcaagggg aggcagtaaa aaaagcagtc
    30661 catcgtatgg gatatgaaac aatcgaagat atccgaatag gaaaatactt tgagatacaa
    30721 cttgctgatg cagaagaacc aatcgataca gtgattgaaa cgatttgtga caagctgctt
    30781 gcaaatgtaa atatggaaac ataccgatat gaaatcaaaa aaatggagga agtataacat
    30841 gaaatttgcg gtcatcgttt ttccaggttc aaattgtgac gcagatatgt tatgggcagt
    30901 tcgcgagatc atgggcgctg atgccgaatt tgtacggcat gatgagtcct ctttagaagg
    30961 atttgatggg gttttactgc cgggaggatt ctcctatggt gactatttga gatgcggtgc
    31021 gattgctcgg ttttctacaa tcatggaaga agtgattcgt tttgctgaag aagggaaacc
    31081 agtattcggt acatgcaatg gattccagat attgacagaa gcaggacttt tgccaggtgt
    31141 actgagacga aatgagtctt tgcattttat ttgcaaaact gtaccattga aagtcaaccc
    31201 caagacggcc tttacttcag agtatgaagc cgacgaaata atctatcttc cagttgctca
    31261 tggggaagga aattatttct gtgacgaaga aacacttcaa gaactaaaaa aaaataatca
    31321 gattgccttt acttataatg acaacatcaa cggcagcgtg gaaaacattg cagggattac
    31381 gaacaaagca gggaatgtgt taggaatgat gcctcatcca gaacgtgcag tagaagactt
    31441 gctaggatca gaagatggga aacggttctt tgcttccatt ttaaaaaact tcggaaaggt
    31501 gaccgtatag atgaaaacat tgaaagaacc gacagctgaa gagatcaaga aaaaaagaat
    31561 ctatgccgaa tggggattga ctgatgaaga atatcgaatg atcgaagaag atatcttagg
    31621 aagaatgcct aattatacgg aaactggact gttttctgtt atgtggagcg aacattgttc
    31681 ctataaaaat tctaaaccgg ttctacgcaa atttcctact agtggacctc atgtgttgca
    31741 aggccctgga gaaggcgcag gcatcgtcga catcggtgat ggactagcag ttgtcttcaa
    31801 agcagaaagt cacaatcatc cttcagccgt ggagccttat gaaggagctg cgacaggagt
    31861 tggcggaatc atcagagata ttttcagcat gggggctcgt ccaattgcgt tgctagattc
    31921 attgaggttc ggcgaattag ataatccaag aacgaaatat ttactagaag aagtagttgc
    31981 aggtatcggc ggatacggca attgtatcgg cataccgact gtaggcggcg aaattgcatt
    32041 tgatccttgt tatgaaggaa acccattagt caatgcaatg tgcgtaggtt tgattgaaca
    32101 caaacatatc cagaaagggc aagccgctgg cgtcggtaat tcgatcatgt atgtaggtgc
    32161 aaaaacaggt cgcgacggta tccacggagc aacttttgcc tcagaagaat ttaatcaaga
    32221 agaagaacag caacgttctg ctgtacaagt aggcgatcct tttatggaaa agctgctgct
    32281 tgaagcgtgt ttggaattaa tcttgcatca ttcggattct ctaataggta tacaggatat
    32341 gggagcagca ggacttgttt catctagtgc ggaaatggct tcaaaagctg gctcaggact
    32401 tatattgaca ttagatgaag tcccacaaag agaaactggg atgacacctt atgaaatgat
    32461 gttatcggaa tcacaagaac ggatgttgat ttgtgttaaa tcaggagagg aagaaaaaat
    32521 ccaagaacta tttcagaagt atgatctaga tgcagtcact atcggtaaag taacagacga
    32581 cgggcaatat cggctatatc atcaaggaga agaagtagca aatctgccag tcgatgcatt
    32641 agctgaagat gcaccagttt atcataaaga aatgaaagaa ccagctcgaa tcgtagaatt
    32701 tcagcagtta gctccttatc agccagttat cgaagaacct ggacaagtat tgcttgatct
    32761 gctgcagcaa ccgacgattg cttcaaaacg ttcaatctac gaaacttatg attcacaagt
    32821 acaaaccaat acagttgtcc gtccaggaag cgatgctgct gtgatgaggg ttagagggac
    32881 gaataaagcg ttagctatga ccacagactg caacgcgcgc tatctgtatt tggatccaaa
    32941 aatcggagga caaatagcag tggcagaagc tgctagaaat attattgcta gcggtggtaa
    33001 gcccttggcg atcaccgact gcctgaacta tggttctcct gataaaccag aagttttttg
    33061 ggaattatcg acttcagctg acggaattgc tgctgcgtgt gaaacgttag gaactcctgt
    33121 tatttcagga aatgtctctt tatataatga aacggatggt caagcaatct atccaacacc
    33181 aatgattggt atggtcggat tgattgagga tcataaacat atcactactc aggaattcaa
    33241 aaaatcaggg gatctaatct atatattagg taagacgttt gcagattttg atggcagtga
    33301 attacaaaag atgcagcttg gaagaatcga aggtgtgatc cgaaactttg atctatccat
    33361 tgaaaagaga aaccaagagt tagtattgac agccatccaa aacggattga ttgaaagtgc
    33421 tcatgactgt tcagaaggtg gcttggcaat tgcactggca gaatcagctt tcaaacatca
    33481 gctagggata tctgtacagt ttgaattgtc ctctgctcaa ttatttgcag aaactcaatc
    33541 aagatttgtg ttgacagtcg caccggaaaa taagacacga ttcgaagaaa tgatgggaga
    33601 tgctgctgtt ttagcaggta aggtgacgga tgaagcgata atcgaaattt cagcaactga
    33661 cggtcagatc aaaatagaaa ctgcagtagc aagaaagtgc tgggaggatg caatcgtatg
    33721 tcttatgaag tgaagagttt aaatgaagaa tgcgggatct tcggtgtttg gggtcatcca
    33781 gacgccgcta gtgtggcata cttcgggctc catagtcttc agcatcgagg acaagaaggt
    33841 gcaggtatcg tgtccaatga tcgaggaaag cttaaggggc atcgagattt ggggctgctt
    33901 tctgaggtat tcaaagatca aagaaaattg cagcagttaa caggagaagc tgcaatcgga
    33961 catgtacgtt atgcaacagc aggcaatgga agtgtggaca atattcagcc ttttctattc
    34021 aaatttcatg atcagtcgat cggcttagcg cataatggta acttgatcaa tgctcgttcc
    34081 cttagaaaag agttagagga aaatggggcg atcttccatt ctaactccga tacggagata
    34141 ttgatgcatt tgatccgacg aagtgaagaa acagattttt taaataaatt aaaaagtgct
    34201 ttgaatgaag tcaaaggtgg ctttgcctat ttattaatga cagaaacggc aatgattgcc
    34261 gctttggacc caaatggttt tcgtccatta gcaatcggac aaatgaaaaa cggagcatac
    34321 gtgattgcct cggaaacttg tgcattagaa gttattgggg cacgttttat aagagatgtc
    34381 cagcctggtg agatagtgat catcaatgac gaaggaatcc agattgattg ctttacgaag
    34441 gacacgcagc tttctatttg ttcgatggaa tatatctatt ttgccagacc agattcaaac
    34501 atcgcaggga tcaatgtgca tactgcacgg aaaaatatgg gacggaattt agcgaaagaa
    34561 tcgccagtaa aagcagatat ggtcgttggc gtacctaatt cttctttgtc agccgcaagc
    34621 ggttatgcgg aagctagtgg aatcccttat gaaatcggat tagtaaaaaa tcaatacatt
    34681 gcccgaacat ttatccagcc aacgcctgag ctaagagagc aaggtgttcg aatgaaatta
    34741 tctgctgtac gaggagtagt ggaaggtaaa aaggtgatta tggtcgatga ttcaattgtt
    34801 cggggtacga caagcagacg gatcgtccat cttttgaaag aagcaggggc aaaagaagtc
    34861 catgtgagga ttgcttctcc tcctttgaaa tatccatgtt tttacgggat tgatattcaa
    34921 acgcgtaaag aactcattgc ggcaaatcac acgattgatg aaatcaaaga atgtatcggt
    34981 gcagattctt taggtttttt aagtgaagag ggtctgatcg aatcgatcgg tctggaaaaa
    35041 gatgctccgt attcaggatt gtgtatggct tatttcaacg gagattatcc gacgccgtta
    35101 tatgactatg aagaaaaata tcaggaatca ctaaaagaaa aagtatcgtt cttttaaaag
    35161 cagaccaaga agggagtata tgaattcaat ggcaaatgca tacgcaaaag ctggcgtaga
    35221 tgtcgaagct ggatatgaag tagtagaacg gatcaagaag catgtcaaaa aaacggaacg
    35281 tttaggtatg atgggcgcta taggaggatt cggcggttgt tttgatttat cggtctttca
    35341 attaaaagag ccagtccttg tctcggggac cgatggcgtg gggacgaaat tagcagtggc
    35401 aatcgaagca gacaaacacg atacaatcgg gatcgactgc gtagcgatgt gtgtcaatga
    35461 tatcttagca caaggcgcag agccgttata tttcttagac tacttagcaa cggggaaaaa
    35521 tgatccgtta cgtttggaaa atgtagtaaa aggtgtagca gatggatgtg ttcaaggaaa
    35581 tatggcgctg attggcggag aaacagctga aatgcctggt atgtactcag gtaatgatta
    35641 tgatctagcc ggatttgctg tagggatagc tgaaaaatct caattattga caggagaaac
    35701 gatcaaccca ggagatgtgt tgcttggaat agcatctagc gggattcatt caaatgggta
    35761 ctctcttgtt cgcaaaattt tctttgagca gcagcagttt tctttatcat caaaactgcc
    35821 agaattgaaa aaaacacttg gcgaagaatt gcttgagcca acgaaaatct atgtttcttc
    35881 cttgcttccg ctgatcaaag aaaagaaaat aaaaggagct gcacatatca ctggtggagg
    35941 gtttgtagaa aatatcccgc gaatgttacc agaatctatg gctgcacaaa tcaaacttgg
    36001 ctcatggccg attcttccaa tattcggctg tttacaaaaa tatggtgaaa ttcctgagat
    36061 ggagatgtat gaaatcttca atatgggcat cggtatggtc ctggcagtcg aagaatcgaa
    36121 agtaaaagaa atagtacacg aaattgagca agctggcgaa aaagtttatg aaatcgggaa
    36181 agtgatcgcc aaagaaaaac atcgtgtggt gtttatagga gaagaacgat gagaatcgct
    36241 gtttttgctt ctggaaacgg aagcaacttt caagcgctag ccgattatct atcgaaaaaa
    36301 ggattggaat cttcgattga ctggttgttt tgtgatcagc ctgaagcata tgttttgaaa
    36361 cgtgcaactg cgttgagtgt accggcagat tgtttttcac ctaaagaatt tgattcaaaa
    36421 aaagagtatg aagaagcaat tttgcataaa ttgaaagaaa aaaagatcga tttgatcgta
    36481 ttagctggat atatgcgaat cattggaccg gtattgctga aaaattatga taaaagaatc
    36541 atcaatatcc atccgtctct tttacctgcc ttccctggtt tgcatggcat acgtgatgcc
    36601 tttgaagctg gagtaaaaga aacgggtgtc acaattcatt atatcgacca aggtgtagat
    36661 actggaccaa tcatccggca ggaaaaagtg agaattgaac aggaggacac gttcgattct
    36721 ttagaagaaa aaatccatag agtagagcat cgaatctatc cagaagtgat tagtgaaatt
    36781 attgaaaatg gaggctatct gaaatgacaa gagcattgat cagtgtatca gataaaactg
    36841 ggattgtagc attcgcccaa ggtttgattg aacaaggagt agaaatcatt tcaacaggag
    36901 gaacaaagca tgcgttggat aaagctggga tcaaaacgct ttcgatcgaa gaagtgacag
    36961 ggtttcctga aatgatggat ggccgtgtca aaacacttca tcctaaaatc catggtggtc
    37021 ttttaggaag acgcgatctc cctagccata tggaggcaat ggaaacggaa aatatccaac
    37081 caatcgactt tgtttgtgtc aatttatatc ctttcaaaga aacgattatg aaaccagatg
    37141 tcgaaatagc agaagctatt gaaaacattg atatcggtgg tcctagtatg ctccgtagtg
    37201 cagcaaaaaa ccatgaattt gtcacctctg ttgttgatcc atctgactat gaagaagtac
    37261 tttcagaatt acgtcagtat gggcatactt cactttcttt cagacaaaaa ctagcggcaa
    37321 aagtctttcg tcatactgcg gcatatgatg cactgatcgc tcaatactta acggattggg
    37381 tggaagaaaa agaaccggaa aaattgacac ttacgtatga acgaaaacaa acgcttcgtt
    37441 acggtgaaaa tagccatcaa gccgctgcct tttatcagtc cgctcttctg gaaaaatatt
    37501 cgatcgcagc agcaaaacaa ctccatggga aagaactttc ttataataat atccgagatg
    37561 cagatgctgc gctacggatc atgaaggaat atgacgagcc aacggtagtc gccttgaaac
    37621 acatgaatcc ttgtggtatt gggacagcat ctacgatttt agaagcgtgg gaagcagcgt
    37681 atgaagcaga tcctgtttca atctttggtg ggatcatcgt tttgaatcga gaagtagatc
    37741 tgccaacagc agaacagatg cataagctgt ttctagaaat catcattgcc ccttcttata
    37801 cacaagaagc tttggaatta ctgcaaaaaa agaaaaacat ccgattactg acagtagact
    37861 ttgcgcagga agaaaatcaa aatcgagaag aaacggtctc agtcttaggt ggacttcttg
    37921 tacaagatca agatctggca atagaaaatg aagaagagtg gaaagtcgtg acaaaacgta
    37981 agccgactcc agcagaagca aaagcattag tgtttgcttg gagagctgtc aaacatgtga
    38041 aatctaatgc gatcgtactg gcaaacgaac gtcagacagt aggaatcgga gccgggcaga
    38101 tgaatcgagt cggttcagta aaaattgcga ttgaacaagc gcaagagaaa atggaaggtg
    38161 cagttttagc tagcgatgct tattttccaa tggatgattc ggttgaatat gcagccaaac
    38221 atggtataaa agcaatcatt cagccaggag gaagcatcaa agaccaagat tctattgata
    38281 tggcgaataa atacgatcta gcaatggtct ttactgatgt tcggcatttt agacattaga
    38341 gaggagtcgg ataaatgaac attttggtga tcggtgcagg tggtcgtgaa catgcaataa
    38401 gtaaaaaact tttagccagt ccgaaggtgg atacggtgta ttgtgcgcca ggaaatccgg
    38461 ggatgacaaa agatggtatc aattgtgtcg ctatcagtga gcgagatcat tcagcgttaa
    38521 tccattttgt taagaaagag gctattgatt ggagtatcgt tggtcctgaa gttcctttgt
    38581 taaatgggat cgtcgatgat tttatggcgg aaggattgaa aatcttcggt ccgacaaaag
    38641 cagcagctct gatcgaaggt tcgaaaagtt ttgctaaaca attaatggat acttatcaaa
    38701 tcccgacagc taaatccaga agttttgaat gttacgaaaa agcagcagcg tatatcaaag
    38761 aaaatggtgc gccaatcgta gtgaaagcgg acggcttagc agctgggaaa ggtgtagtcg
    38821 tggctaccac agtgaaggaa gcgctggatg cggcagaaca aatgttgaac cagcatcgat
    38881 ttggggatag tagcaaaaaa atcgtcgtag aagagttttt ggcaggagaa gaattctccc
    38941 ttttggcgtt tgtccgtaat accaaggtgt atccgatggt catttcgcaa gatcataagc
    39001 gggcatttga taacgataaa gggccaaata caggcggaat gggtgcttat tcaccagtac
    39061 cgcaaatttc aaaaaagatg attgaaaaag ctgtggaaga agttttaaaa ccagcggctt
    39121 tgggaatgaa agaactagga cgctctttca cgggtgtttt atatgcgggt ttgattgcta
    39181 cgaaggaagg accaaaagtg atcgaattca atgcgcgttt cggtgatcct gaaacgcaag
    39241 tcgttctttc tcggttgaag agtgactttg cgcaagtaat cgatgattta ttagagaatc
    39301 gtacagtaga gttaaagtgg cagcaagaag gatacaatgt aggcgttgtg gttgcagctg
    39361 ccggttaccc cgaagaatat gagacaggaa tggttctacc agattttctg gaagaagagc
    39421 tttctgttta ctatgctgga gtttcctcaa ataacggcaa actagttgga gcaggaggac
    39481 gtctttattt agtagaagca tacggtgaga cgatcaaaga agcacagaaa aaaatttaca
    39541 ccgcgttaat ggataaaacg acagatggaa cattttatcg tacagatatt ggagaaaaag
    39601 ctgccaatag cgaactgatc gtgaagtaaa tcagctgctt ccatttataa aaaatacaac
    39661 aaacataatc ggaagcgccg attttagtga agccttttca taaagagtgt ggtacacttt
    39721 tgttgtgtat ataaataagg aggagttcag atgaaaaaaa ttcaattagg tacttctgat
    39781 cagaaagcag ctgcagtgat cttaggctgt atgcgtatca acaatgcgga agatccagta
    39841 aaagtgattg agacagctta tgaaaacggc attgattttt ttgaccatgc agatatttat
    39901 ggaaacggtg aatgtgaaga aatctttgca gatgctctag caaaaacatc aatcaaacga
    39961 gaagatcttt ttattcaaac aaaatgtgga atcgttccag gtgtgatgtt tgatttttct
    40021 aaaaaacata tcattgaatc tgtagaaaaa agtttgaccc gtctgaaaat ggattatgtg
    40081 gatgctttac ttcttcatcg tccagataca ttggtagaac cagaggaagt agctgaagcg
    40141 tttgatgaat tggaacggtc aggaaaagtt cgttattttg gcgtcagcaa tcaaaaacca
    40201 atgcaaatcg aattgctgaa aaaatatgtt cgtcaaccat tagtagctaa tcagctgcaa
    40261 tttggcttga aacatactgg aatgatcgat caagggattc atgtcaatat gacagatgaa
    40321 gcaagtatcg atcatgacgg tagtgtactt gattattccc gattgcatga tatgacgatc
    40381 caagcatggt caccatacca gtatggattt tttgaaggtg tatttatcgg gaacgaaaaa
    40441 ttccctgaat taaaccaaac attagaagaa ctagcagcta aatatcaaac gacaccaact
    40501 ggcttggctt ctgcttggat tttacgccat ccagccaata tgcaagtgat cgccggtacg
    40561 atgaacgtag ggcgaatcaa ggaaatcgct caagcttcag aaattaatat gtctcgggaa
    40621 gattggtacg aattgtaccg tgctgctgga aacattttac cttaaagatt gtcataagca
    40681 ggtcaaaagg gctataaatt aaaaagacag aataacttga aagctgtttt cagcttcgag
    40741 atattctgtc tttttttatt gcaaatggaa agagtatcat tgtacggatt tcgtttatta
    40801 gttatttttg tttttaagga aaagctgtgt ccgatattct tttggagaaa tcccttgttt
    40861 tttcttaaat aaataactga aatagttagg gtcattataa ccaatttcaa aagcaatatc
    40921 tgaaatacga tagtctgatt gctgcaataa tttttttgct aattcgattc tttgttctgt
    40981 cagataatcg atgaatgttt ggttaaacga ttgagaaaaa atcgtactga aataagaggg
    41041 acttaatgca acttgttgag cgacccaagt taaggacata tctggatcgg taaaattttc
    41101 tttgataaaa tccaatgcat ggttcaaaat tggctgatat ttgttccttg aaggctgtga
    41161 gggcagagca gttaagaaag aaatgaacat ataaactgtc gaacggtaaa gcgagtcgtc
    41221 ggcgctgatt gctaagcgtt gactggtgga tgtgcaatga accatttctt gcgggatttt
    41281 cttttctttc aggcagacat gctggagtag cttagtcaag acaaataaac gatataatcg
    41341 tgttcgagtt ggtgtgcctt gtggtttcgt caagtgttcg atgtacttag atacttcgtt
    41401 tttcgataat gaagacaaat caagtgagag gtcaaagtaa aagacagaat caactggaag
    41461 tttcgcttct tgaatcaaat cctcatagct gataatttgt tctttaaggg aactggcggt
    41521 ttcaagtatc atctgcgtga tctcaaaaga tgcaggtaat tcgctgattc tttctgcgac
    41581 aggaccaatg gcgacagaaa aattattttt ttgtcccttt tctaattcat ggaccaacgt
    41641 ttgggctacc tgataactgg tctcgatcac attttcttca agagaatcaa ctattaaaaa
    41701 tttgatgaat cgagaggaaa cagcagagaa gatcacttgt tgattctccc taaataaaaa
    41761 cttcaaataa tcactgagat gagcgtaatc ttcaaagtct gtactgactt ggtttgctgc
    41821 taataatacg gtcatttttt tccctgctaa agagcgattg aaagattcag caagtttcaa
    41881 tgtttcactg atcgtaagtg agcctttgaa caaaccgttc aagaaatgat tttttttcaa
    41941 ttcgaaaaca agatcagaag aagtgtgcgt ttctttttgc tgcaaatcta aagcagttac
    42001 tgctttttct attgcttgtt tcaattcgct acttttaatc ggtttaagca gataatcatc
    42061 tgcctgtacc tggattgctc ctttcatata atcgaaatcg tcgaatccac taataaatat
    42121 gagacgagtc caaggaagta gtttccttgc ttcttttgaa aaagtcaacc cgtccatgaa
    42181 aggcatttgg atatcagtca gaatgatgtc gggctgtaag tcgataattg aagacagtgc
    42241 catctcacca tctccagctt cgccgacata agtgattgga taataagaac caaggacagt
    42301 tatttgttcc cgcaagttat tgcgaatgag gtattcgtct tcgatgataa aaactttata
    42361 catgtttgtt tcctccaatt gttttgggag atagagggat catcagtgtg acagttgttc
    42421 cttctcggta tttgctgtca atcgtgatag gtttttgatc atttccgtaa taaagaagga
    42481 gacgcttgtt tacgttgtaa agtccgtagc cgatactgaa atctgaatcg atccctttgg
    42541 ctaactcttt acgtatttct gccagttttt ctgcagggat gccaatcccg ttgtctataa
    42601 ctttgaattg gatcatctca tcaattttgc atgtggtaat acgaataaat cctttgtgac
    42661 ggacgtactt cgttccatgg tatacagcat tttcaatcaa tggctgcaag atcattttta
    42721 aaatagaaac aggaaaaagt gtttctggta tatcgatctt atagtcaagc atatggccgt
    42781 atcttatttt taagatgact agataatcat tgatatggct aatttctttt tcaagaggaa
    42841 tccagtcttg tcctttgctt aaagacgtac gaaaaaagcc ggaaagtgca tgggtcatag
    42901 tcagagcttc ttcaaagcag tcttgttcga tcaaagaaat aatggcatcc aaactgttat
    42961 aaataaaatg gggagtaatc tgagcttgca atacacgaac ttcactttgt gctaaatggt
    43021 attgtttcaa agcgttctcc cgtaaagact ggtttagatc ttccgccatt ttattcatgc
    43081 tagcggtaag tgtttgtaat tccagtgttt ccggcagggt taaacgaaag ccaaggttcc
    43141 ctgaagaaag ttgttctgac atctcgatca gctgattgat cggttcttgg acctttctct
    43201 ctaaaaagcg acgattcttt ttcgcataga aaaaaatggt actaagaact ccaagttcca
    43261 ctattgttaa tagaatgagc gagcggacaa gtgtcgtatt ttttttgctt gctaagtcga
    43321 tctccacacg aacaaaatct tgtaagatat ctgacagcag ttgagtgaca gaatctacct
    43381 gattgatgat ctcttcattg gtatccataa aatcttttgc caagatatta ttgatcagct
    43441 cgttttgata atcttccagt gtatcgatcg tacgtagcga tacatctaac gtactaattt
    43501 ctttaagtgt atttgtatta tttttgatct ctcgaatatc attcctaagt tcttctagga
    43561 tattttcctc attgaactca tctacggtta cttggccaga aatcaagtcc cacatacttt
    43621 ccaaaacttt ttgatcaacc ttcaaagcaa ttgcatctgc tttttggata tttgcgatcg
    43681 tctgttgata aatcaaaagc tgttgcgaat ataacagtat gctcagtagc aaagggataa
    43741 cagcaaatag aagcatggct ttgtttgctt gggcaaaaat ctgttttatg cttaaatttt
    43801 ttgtcatgat acttctccag tcaataattt ctggttggga tgttagctat attctgctgg
    43861 gaaaagacag tctcggaaat aaaaatatct ttaggtaatg tttttcctgt ttgaatattt
    43921 ccaaaataac gagtaacggt attggctaca taccagccga catcaggttt acactcgact
    43981 acacaattga cgattcctga gcgtagcttc tcgatcatat cttcttgtcc atcaatagtt
    44041 acaatgatca aatcttctcc aggtttgatt gatgtttctt ttatcgcagc taaagcaccg
    44101 tgagtcattt catcactatg gctgtataat acatcgattt cggataaatc atttgtttct
    44161 aaatatcgtt tcatctggtc ttttcctttc atccgaataa aatcaccgac aattcggtga
    44221 acaatagtca tcggaggttt atggtcgatg gttccatctt tttttagggt tggtttacga
    44281 ttgattgatt ccaaaaatcc ttcggagcgt agcttggtcg gtgtggagtt ctctgaacca
    44341 gcaagttcta ggattctgat ttcctgtttc tttgaatttg tgaagtgatt gctgacaaat
    44401 aaacccgccc gatttccttc tgctttgaaa ctggggccaa tgtgggtgac gaaaagctcg
    44461 ggatcattcg tttgaatatg tctgtcgaca agtatgacag ggatccctgc tcgctttgct
    44521 tcttttaata cagagtccca cccggattct tgcaaaggag taaaaatgat catatccact
    44581 ttataggcaa tgaacgtccg tatatcttgg atttgccgtt cctgattcat gtagccattt
    44641 cggtagagaa cttggtaatc ttctttttca agcgcagtga taattgattc agtatgcttt
    44701 ttccgccagc tactctccgt tcctgattgc gaaaaaccaa cgactagtgg gtcaggtgct
    44761 tcctttgtat taggtgtaca ccccatcatt tggtaagcga ttacaacaag ggctaaaaaa
    44821 aataaaacac gtttcacttt aaatcactcc atctggattt gttagtacta tcttatcaga
    44881 taaaagggaa aatcaaagtc aaaaggaatc aatcgaaaaa aatccaagaa acttaaaaaa
    44941 atccaagaca aaaaaagtac acctaaaaaa tttaaagtaa atcccataaa aaaatcaatg
    45001 ttaacgcttt ctttattagc tatactcggt gtatcaattg aaatggggga taaaaaatga
    45061 aaaacaaatt tagaaagatt gttgggacta tcgctatttt gaccgcaagc attctattaa
    45121 gtgcgtgtgg caattcagga tctgcagatg atagtacggg gtatgtagga atcgctatgc
    45181 cgaccaaatc agcagaaaga tggatcgctg atgggaacaa catggtctcg gaattagaaa
    45241 aactgggtta taaaacagat cttcaatatg gagaagataa agtagaaaat caagtagcac
    45301 aaatagaaaa tatgattaca aaaggggtag atacacttgt gattgcttct atcgatggtt
    45361 cggctttaac tgatgtgtta gctaaagcaa aagaagcaga tatcaaggtg atcgcctatg
    45421 atcgtttact gatgaattca gaaaatgtcg attattacgc gacttttgat aattttggag
    45481 taggtgtatc gcaagcagct tatattgaag agcacttagg attgaaagaa ggaaaaggac
    45541 cattcacgat tgaattattt ggtggctcgc ctgacgacaa caacgcacta atcaattaca
    45601 acggagtgat gtctgtttta caaccatata tggacaacgg tcagttggtc gtgccatctg
    45661 gacagacgag tttcagtcaa atcgctacgc ttcgctggga tggttctacg gcgcaagcaa
    45721 ggatggataa tctgttaagc gcaaattata ctgaccaaac attggatgct gttttgtcgc
    45781 catatgatcc aataagttta ggaatcattt cgtcattaaa aggcgtgggg tatgggagtg
    45841 aaagtaaacc tttacctgtg attactggac aagatgcgac agttgctggc gttaaatcga
    45901 tcattgccgg ggaacaaaca caaacgatct ttaaagacac acgtatctta gcaaaaaata
    45961 cgattgaaat gatcaaagca atcagtgatg gagaagaggt tccggtcaat gatactgaaa
    46021 cttatgataa tggggtgaaa actgtcccta cgtatttagc aaatacagta tctgtcgata
    46081 aagataatta tcaagcagag ctgatcgaca ccgattatta taaagaatcc gatctgaaaa
    46141 attaagagga accaaacaag gaactaaaga gatctaagtc agagagagga taagaattat
    46201 ggcggattgt attttaaaaa tggcagatat caccaaaaaa ttttctggaa tccgagcgtt
    46261 agattgcgtg aatctgatga ttgaacgtgg ggaaatccat gcattgtgcg gagaaaacgg
    46321 agcgggaaaa tcaacattga tgaatgtctt gagcggcttg tatccatatg gctcctatga
    46381 cggggaaatc ttttatgatg gaaagctgtg tcaatttaaa gatttgaaag atagtgaaga
    46441 aaaaggcatc gtcatcattc atcaagaatt agcactaagt ccttatcttt caataaaaga
    46501 gaatattttt ctcggaaatg aacaagcaga aagaggcgtg attgattggg aactgacaga
    46561 aaagaaaaca tatgaactgc tgaataaagt cggtttgtct atcgacccga atcttctagt
    46621 atcccagatt ggcgtagggc aacagcaact agttgaaata gctaaagcat tatcaaaatc
    46681 cgtccgtctg ttgattttgg atgagcctac cgctgcattg aatgaagaag aaagcgcgaa
    46741 tttgctgaga ttgatccgag agttgaaaga gcaaggtgta acctccatca ttatttcaca
    46801 taagctgaat gaaatcgtgg atatcgcaga tcgaatcacc attttacggg atggacagac
    46861 gattgagaca ctagaaaatg aaatgatcag cgaagagcat attattcgcg gaatggtggg
    46921 cagagattta gttgatcgtt atcctgaaag aaaaccggat attggagaag tttattttaa
    46981 agtagaagac tggacggtct atcaccctct tgatcacgag cgaatcataa acgaccacat
    47041 caacttgcat ttgaaaaaag gagagattgt aggaatagct ggactgatgg gagcgggcag
    47101 aactgaattc gctatgagtc tatttggaca ttcttatgga agcaagatat ccggacgtat
    47161 attaaaggaa ggggcagaga tatcagttaa gaccgttcct tcagccattg caaacggact
    47221 cgcttatgtc tcggaggacc gaaaatcttt aggactgaat ctgctgatgg atattcggga
    47281 aaacgtgacg ctgagcagtt tggataaaat aagtcaaaaa ggagtattag ataaagaaaa
    47341 agaagtaact gaggcagaaa atttccggaa aaagatgcgt ataaaaacaa actccatcca
    47401 tcaaattgtc agtagtctta gtggtgggaa tcaacaaaaa gtcgttttat ccaagtggct
    47461 gatgacacaa cccgatattc tttttttgga tgagccaacc cgtgggatag atgttggggc
    47521 aaaatatgag atctacacga ttatcgaaga aatggcagca aatggcaaag ctgtctgtct
    47581 tatctcttct gaacttcctg aaatattagg gatgtgtgat cgaatctata cgatgaacga
    47641 aggacgtatt acaggagaag tctcgcgaga agatgcagat caggaagtct tgatgaaatt
    47701 aatgacgaaa gaagaggtgg gttaagttgg aacaggcaaa aaatcttacg gataaaaaag
    47761 agaaaaaact aaatttgaaa agtagagcag ctgatctttt tggtcgctac agcatggtga
    47821 tcattttagc gggactactt attgcgtttc aattgatgac ggatggtatt ttctggcgtc
    47881 cattgaatat aactaacctt gttctgcaaa atagccatat attagtacta gctgcaggga
    47941 tgttattagt tgtgctctta ggtcatgtgg atttgtcggt agggtcagtg atggcgtttg
    48001 ttggtgcaat tgcgggcatg atgatggtca atcgccaaat gaacccgtgg atgacagtta
    48061 tcgcatgtct tgcagtaggc gggctgatcg gcgcatggca aggtttttgg gtagcttatg
    48121 cagggatacc ggcgtttatc gtgactttag caggattgct gatgtttcgt ggactgacac
    48181 aagttgttct aggaggccaa tctctagcac cttttccagc tgttttccaa aaaatgtcta
    48241 cgggttattt accagactta agcgaaggaa gcagccttca cttcttgaca ttgattttag
    48301 gaatgatcat cacgatcgtg ttagttgttg gtcaatggcg aacaagaaat cgtcggaaaa
    48361 atcatttatt tgaagtggaa tctccaacag ctttcttggt aaaggcggta tttacagcag
    48421 tcgttgtact aggaataact tatatctttg cctcttatca agggtatccg attattttga
    48481 tcattcttgg tttgatcgtt gcagcatatg ggtttttgac aaataaaaca gtagcaggtc
    48541 gacagattta tgcgacgggc ggaaatcgaa aagcggctga actatcaggg atcaaaacaa
    48601 agcgaatcac gttctgggta ttcgtcaaca tgggagtcat ggcagcttta gctggattag
    48661 ttttagctgc tcgattgaat gcggcaacac ctcaagcagg tacatcgatg gaactggatg
    48721 caatggcggc agtatatttt ggtggtgctt cgacttccgg cggcattgga acaatcatgg
    48781 gtgcgattgt cggtggcttg gtcatgggtg tattgaacaa tggcatgtcg attttaggcg
    48841 tcggggtaga ctggcagcag gcaatcaaag gattgatctt gcttttagcc gttgtgctag
    48901 acttgtataa taagaaaaaa cgaacaacgt aggagaacgc cggttattca gaaaaaagac
    48961 tgtgacaaga catttgtcac agtctttttt tcgctaaaag cgaacattca ttgtttcgtt
    49021 tgtatagact aaaaataata tatgtttttt taccattcgt ataaattctc tttttgctct
    49081 tgattttttt gcttaattga gttaaattac atagggcgct aaaaaaagcc ttgattaaat
    49141 taataatgtt cgtgttttgc tggatgtgaa catcaggagg ataatgtaat gaaagtattt
    49201 gattacgaag atattcaatt aattcctaat aaatgtatcg taaatagccg ttctgaatgt
    49261 gatacaacgg tcacattagg taaacataca ttcaaaatgc cagtagtgcc tgccaacatg
    49321 cagacgatta ttgatgaaac aatcgcagaa ttcttagcgg aaaatggtta tttctatatc
    49381 atgcatcggt ttgatgaagc agctcgaatt ccgtttatca aaaaaatgaa aaagcgtgga
    49441 ttgattacct cgatcagtgt tggcgtcaag aaagaggaat attcctttgt agagaagttg
    49501 gcagaagaat cgctaaatcc tgattatatc actatcgaca tcgcgcatgg acatgctaac
    49561 tcagttattg atatgattca gcatattaaa aaatatttgc ctgaaacttt tgtgattgcc
    49621 ggtaatgttg gtacaccgga agccgtccgt gaattggaaa atgcgggcgc agatgcaaca
    49681 aaagtcggga ttggtccagg aaaagtatgt attacaaaaa tcaagacagg ctttgggact
    49741 ggaggctggc aactggcagc tcttagatgg tgtgcgaaag cagctcgcaa gccgatcatc
    49801 gctgacggtg ggatcagaac acatggcgat attgcaaaat ctgtccgttt tggtgcgaca
    49861 atggtcatga ttggttcatt gtttgccggt cacgaggaat ctcctggcga aacaaaagtc
    49921 gaaaatggaa tcgtgtataa agaatacttt ggttctgctt cagaattcca aaaaggcgaa
    49981 aaacgaaatg ttgaaggaaa gaaaatctgg atccaacaca aaggatcttt gaaagataca
    50041 ctagtggaaa tgcaacaaga ccttcaatca tctatttctt atgctggagg aagagatctg
    50101 gaagccattc gaaaagttga ctatgtcatc gtgaaaaatt cgatttttaa tggagacaca
    50161 atctaaaaaa taaataaaat attaggatgt tgtgaaaaag ttgtcctgca ttaagtaata
    50221 agaacagcca aacaaaaata gttctttata tgttttgttt ggctggaatt attatcgcag
    50281 atacaagctt ttgaacatca ttattcagaa taagggactg tgataagatt tttgtcacag
    50341 tcccttatgt tttgcaaaaa aagtttttct tttttctcgt aaattcggta aaatcaaaag
    50401 aaaaaataga caatagaaaa gagaagctta tgtgggaaaa agtagagaaa aaacaaggac
    50461 cgatttatcg tcaaattatg gaacagatta tgagagaaat cgaaaacgga aggatcaatc
    50521 ctggaagtca acttgaatca gaacgaaaac tagggcaact ttttggtgtg aatcgttcca
    50581 ccgttgtcca tgcattggaa gagcttaggg agcttggggt actaacgagc aaacgtggca
    50641 gcggatggtt tgttaatcag actgaatggg ggaaattcgc tgttccaaga atcgattggc
    50701 ggcaaatgat ctctcctcgt tatgagcaga cggactggta tgagcaaaaa ataagagaag
    50761 caaagcagat ccaaaaaaca tcgtttcttg atttatacgc tagcgagatg ccagatgagc
    50821 ttttgccgaa ttttgagttt ccttcttatt ctcttgaaga aatcttagcg gaagaaaaag
    50881 aaatggatct tttaggctat actccgttac gtaacaaaat caaacggtat ttggaaagta
    50941 aatttgaatt ggcattttcc cccaaccagc ttcttgtgac tggtggcggt cagcaagcaa
    51001 tctttttgat tttacaaacg attctttcag ctggagaggg gatagctgta gagtcacctt
    51061 ctttttttta ccgattacct cttttcaaag cttcaggaac gcgtttattt gggataccga
    51121 tggatgaaga agggatcgac ttagaaaaac tgaaagaatc gatccataaa aataaattga
    51181 aagcagtgct tatcaacccg aattttcaaa accctacagg aaaagtgatg agtcaaaaac
    51241 gacgagaaaa gctagtagaa ttgtgtcgac agtatcggct tccaattatt gaagacgatg
    51301 tatttacgga tctttcattt ctaaaccaag aagaagtcct tcctatacga acgattgatc
    51361 cggataatgt gttatacgtc ggttcgttat ctagggtttt aggaaaaaca acgaaaatcg
    51421 gttgggtgat aggacctgag acttttatct cgcaactagc tcaagcgcaa gaaatgatgg
    51481 agttttcgat gaatatcctt acacaaatca cagtggctaa tgtatttaat gaagcaattg
    51541 atttgaaaat gcaagatgta agaaaaaagt tgaaagaaaa aagccgactg ataagcgctt
    51601 ggggagattc acaatcgttt ttcaagcttc attcaatttt aggtggttac tatgcctgga
    51661 ttacttggga tgggaaaaaa ctagaccccg aactagcaga aaaagtagta gatatgggtc
    51721 ttggaattgc accaagtcta ctttttgggc aagatataaa tggaatcaga atcaattaca
    51781 gtaggctgga tgaaaaccaa ataccgttgt tttattcaaa gatgaaaatt ctagaaaagt
    51841 ggttaacaga ataatttcac aaagtaaata gattaaagaa tataacagct tggatttaaa
    51901 tttcaagctg tttctttttt ttcggaaaaa gaatacgata taaagaaact aagaaaaaac
    51961 cattatttgt acgtccgttc acgatgtgta aataaaataa atgtttgcaa caaaactgta
    52021 taacaccaac gtttttaaat agaaacagat ggttgtaagt ttgattagaa aatagaaaaa
    52081 atgcagatga aatataaaac gctttcctta ttgtgatttt attcactaat gctgttaata
    52141 tgcggattgg cataatttcc tttcatcgtg aaaatttgtg cttttagctt gtatttctca
    52201 taaatccatg ataatttatt aatgaagacg gttaaatagt gatacagttt tattcactgt
    52261 ttcaatcgca gaatgaagag attttcttat agatgagaga ggaatgtgtg acaaatggca
    52321 aacaaaaaag caccgatcga cttccaagca ctgctagatg aagtcaatgc agatttccca
    52381 gtatatcaag cacttgatca agatggaaac gtagttaaca aagatttagt acctgattta
    52441 tccgatgatg aactcgttga attaatgact catatggtat ggtctcgtgt attagaccaa
    52501 cgttcaacag cgctgaaccg ccaaggacgc ctaggctttt ttgcaccaac tgctggacaa
    52561 gaggcaagtc agctggctag tgcttacgca tttgataaag aagatgttct tcttccaggt
    52621 tatcgggatg tacctcaact agtaaaacat ggtttacctt tatctcaagc ttttttatgg
    52681 tctcgaggac atgctgcagg taattcttat ccggaagaat tgaaagctct accaccacaa
    52741 attatcatcg gtgcacaata tgtacaagca gccggtgttg cattaggttt gaagaaacga
    52801 aacaagaaaa atgtcgtctt cacttatact ggtgatggcg gttcatcaca aggtgatttt
    52861 tacgaagcaa tcaatttcgc tggcgcttac catgcaaatg ccgtatttta tatccaaaac
    52921 aacgggtatg cgatctctac acctcgtgaa aaacaaactg cagcaaaaac acttgcacaa
    52981 aaagctgtcg cagctgggat tcctggtatt caagtcgatg gaatggatcc gcttgcagta
    53041 tatactgtat ctaaaatggc acgggaatgg gcgatcagtg gaaatggacc agtcctaatc
    53101 gaaacactga cttatcgtta tggaccacat acactatctg gtgacgatcc aacccgctac
    53161 cgtacaaaag acacagatga cgattggcag aaaaaagatc cattgatccg cttccgtaaa
    53221 tatttgacgg aaaaaggact ttggtctgaa gaaaaagaag aacaagtcat cgaagcaact
    53281 aaagaagaaa tcaaagcagc tattgctgaa gccgacaaag taccaaaaca aaaggtttca
    53341 gatttcttga aaaacatgtt cgaagtatct ccacaatcaa tcaaagaaca aattgcaatt
    53401 tatgaagcga aggagtcgaa ataatcatgg cacaaaaaac aatgatccaa gcaatcacag
    53461 atgccttagc acttgaacta gaaaatgacg agaatgtcgt tgtttttggt gaagatgttg
    53521 ggaaaaacgg aggagttttc cgggcaactg aaggattgca ggaaaagttc ggagaagacc
    53581 gagtattcga tactccttta gctgaatctg gaatcgcagg attgagtttc ggtcttgcgt
    53641 tagaaggatt tcgtccagtt cctgaaatcc aattctttgg ttttattttc gaagcaatgg
    53701 acgaagtagt agctcaaatg gctcgtacaa gatatcgaat gagcggcact agaaatctac
    53761 ccatcacaat tcgttcgcca tttggtggcg gtgttcatac accagaattg cattcggata
    53821 atttagaagg tttgatcgct cagtctcctg gtattcgagt agtgattcct tccaaccctt
    53881 atgatgcaaa aggactattg atttcttcta ttagaagtaa cgatccggtt gttttcctag
    53941 aacacatgaa actatatcgc tcattccgag aagaagtgcc ggatgaagct tacgaagttc
    54001 ctttggataa agcagcagtt actcgtgagg gaacagatgt atctattatc acatacggag
    54061 caatggtgcg tgaagcaatc aaagcagcag acaatcttgc aaaagaaaat atatctgttg
    54121 aaatcattga tcttcgtaca gttgcgccat tagatgtaga aacgatcatt caatccgtgg
    54181 aaaaaactgg tcgcgtagtt gttgtccaag aagcacaacg acaagcgggc gttgccgcgc
    54241 aagtagtttc tgagatctca gaacgcgcta tcctttcatt agaagcccca atcggacgag
    54301 tttctgcacc tgatacagtc ttcccatttg gacaagcaga aaatgtctgg ttgccaaatg
    54361 caaaagatat cgaagacaaa gtaaaagaaa tcgcggaatt ttaagaaaag aagggacgaa
    54421 acaaagtcat ggcttatcaa tttaaatt
//
LOCUS       DAFEKH010000015        53717 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.016, whole genome shotgun sequence.
ACCESSION   DAFEKH010000015
VERSION     DAFEKH010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 53717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53717
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.016"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            160..840
                     /locus_tag="LP386_000978"
     CDS             160..840
                     /locus_tag="LP386_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBL1918231.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            930..1964
                     /locus_tag="LP386_000979"
     CDS             930..1964
                     /locus_tag="LP386_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBL1918232.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            1978..2313
                     /locus_tag="LP386_000980"
     CDS             1978..2313
                     /locus_tag="LP386_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918233.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            2297..4777
                     /locus_tag="LP386_000981"
     CDS             2297..4777
                     /locus_tag="LP386_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918234.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            4833..6392
                     /locus_tag="LP386_000982"
     CDS             4833..6392
                     /locus_tag="LP386_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1918235.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            6389..7753
                     /locus_tag="LP386_000983"
     CDS             6389..7753
                     /locus_tag="LP386_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBL1918236.1"
                     /translation="MKIVIIGASHEGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            7924..8994
                     /locus_tag="LP386_000984"
     CDS             7924..8994
                     /locus_tag="LP386_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1918237.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            9009..9677
                     /locus_tag="LP386_000985"
     CDS             9009..9677
                     /locus_tag="LP386_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1918238.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            9697..10275
                     /locus_tag="LP386_000986"
     CDS             9697..10275
                     /locus_tag="LP386_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL1918239.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            10676..11587
                     /locus_tag="LP386_000987"
     CDS             10676..11587
                     /locus_tag="LP386_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBL1918240.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(11965..12882)
                     /locus_tag="LP386_000988"
     CDS             complement(11965..12882)
                     /locus_tag="LP386_000988"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HBL1918241.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELDKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            13084..13521
                     /gene="zapA"
                     /locus_tag="LP386_000989"
     CDS             13084..13521
                     /gene="zapA"
                     /locus_tag="LP386_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HBL1918242.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            13579..14127
                     /locus_tag="LP386_000990"
     CDS             13579..14127
                     /locus_tag="LP386_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HBL1918243.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            14242..16602
                     /locus_tag="LP386_000991"
     CDS             14242..16602
                     /locus_tag="LP386_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBL1918244.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKIENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNTYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            16689..17003
                     /gene="trxA"
                     /locus_tag="LP386_000992"
     CDS             16689..17003
                     /gene="trxA"
                     /locus_tag="LP386_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBL1918245.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            17185..18963
                     /gene="uvrC"
                     /locus_tag="LP386_000993"
     CDS             17185..18963
                     /gene="uvrC"
                     /locus_tag="LP386_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HBL1918246.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMVKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            19108..20007
                     /locus_tag="LP386_000994"
     CDS             19108..20007
                     /locus_tag="LP386_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1918247.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            20000..21262
                     /locus_tag="LP386_000995"
     CDS             20000..21262
                     /locus_tag="LP386_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1918248.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPIRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            21423..23321
                     /locus_tag="LP386_000996"
     CDS             21423..23321
                     /locus_tag="LP386_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HBL1918249.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(23651..24370)
                     /locus_tag="LP386_000997"
     CDS             complement(23651..24370)
                     /locus_tag="LP386_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBL1918250.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLVEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     gene            24707..25039
                     /locus_tag="LP386_000998"
     CDS             24707..25039
                     /locus_tag="LP386_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918251.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            25026..27029
                     /locus_tag="LP386_000999"
     CDS             25026..27029
                     /locus_tag="LP386_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HBL1918252.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            27048..27518
                     /locus_tag="LP386_001000"
     CDS             27048..27518
                     /locus_tag="LP386_001000"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HBL1918253.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            27539..28123
                     /locus_tag="LP386_001001"
     CDS             27539..28123
                     /locus_tag="LP386_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HBL1918254.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            28138..29124
                     /locus_tag="LP386_001002"
     CDS             28138..29124
                     /locus_tag="LP386_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HBL1918255.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            29114..29425
                     /locus_tag="LP386_001003"
     CDS             29114..29425
                     /locus_tag="LP386_001003"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HBL1918256.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            29447..31228
                     /locus_tag="LP386_001004"
     CDS             29447..31228
                     /locus_tag="LP386_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HBL1918257.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            31221..32597
                     /locus_tag="LP386_001005"
     CDS             31221..32597
                     /locus_tag="LP386_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HBL1918258.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            32604..33239
                     /locus_tag="LP386_001006"
     CDS             32604..33239
                     /locus_tag="LP386_001006"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HBL1918259.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            33269..34624
                     /locus_tag="LP386_001007"
     CDS             33269..34624
                     /locus_tag="LP386_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HBL1918260.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(34816..36210)
                     /locus_tag="LP386_001008"
     CDS             complement(34816..36210)
                     /locus_tag="LP386_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBL1918261.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            36302..37273
                     /locus_tag="LP386_001009"
     CDS             36302..37273
                     /locus_tag="LP386_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HBL1918262.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            37270..38052
                     /locus_tag="LP386_001010"
     CDS             37270..38052
                     /locus_tag="LP386_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBL1918263.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(38221..38592)
                     /locus_tag="LP386_001011"
     CDS             complement(38221..38592)
                     /locus_tag="LP386_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL1918264.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            38726..39169
                     /locus_tag="LP386_001012"
     CDS             38726..39169
                     /locus_tag="LP386_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HBL1918265.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(39212..40021)
                     /gene="yidA"
                     /locus_tag="LP386_001013"
     CDS             complement(39212..40021)
                     /gene="yidA"
                     /locus_tag="LP386_001013"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HBL1918266.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(40040..41407)
                     /locus_tag="LP386_001014"
     CDS             complement(40040..41407)
                     /locus_tag="LP386_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBL1918267.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(41391..42221)
                     /locus_tag="LP386_001015"
     CDS             complement(41391..42221)
                     /locus_tag="LP386_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HBL1918268.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLEDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            42384..42821
                     /locus_tag="LP386_001016"
     CDS             42384..42821
                     /locus_tag="LP386_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HBL1918269.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            42897..43517
                     /locus_tag="LP386_001017"
     CDS             42897..43517
                     /locus_tag="LP386_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HBL1918270.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            43706..44212
                     /locus_tag="LP386_001018"
     CDS             43706..44212
                     /locus_tag="LP386_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HBL1918271.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            44229..45128
                     /locus_tag="LP386_001019"
     CDS             44229..45128
                     /locus_tag="LP386_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBL1918272.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            45215..46099
                     /locus_tag="LP386_001020"
     CDS             45215..46099
                     /locus_tag="LP386_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBL1918273.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(46291..46362)
                     /locus_tag="LP386_001021"
     tRNA            complement(46291..46362)
                     /locus_tag="LP386_001021"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(46327..46329),aa:Arg,seq:ccg)
     gene            46422..47756
                     /gene="rpoN"
                     /locus_tag="LP386_001022"
     CDS             46422..47756
                     /gene="rpoN"
                     /locus_tag="LP386_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HBL1918274.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            47905..48996
                     /locus_tag="LP386_001023"
     CDS             47905..48996
                     /locus_tag="LP386_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HBL1918275.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            49037..50038
                     /gene="gap"
                     /locus_tag="LP386_001024"
     CDS             49037..50038
                     /gene="gap"
                     /locus_tag="LP386_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBL1918276.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            50148..51338
                     /locus_tag="LP386_001025"
     CDS             50148..51338
                     /locus_tag="LP386_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HBL1918277.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            51442..52197
                     /locus_tag="LP386_001026"
     CDS             51442..52197
                     /locus_tag="LP386_001026"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HBL1918278.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYETGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            52313..53611
                     /gene="eno"
                     /locus_tag="LP386_001027"
     CDS             52313..53611
                     /gene="eno"
                     /locus_tag="LP386_001027"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HBL1918279.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
BASE COUNT        17827 a         9356 c        11350 g        15184 t
ORIGIN      
        1 ttaataaaaa aggaagaata ttcatgtaaa cgattttatt gtttttttct cttttataca
       61 aaaagggtca taatttcaag taagcggatg aattcatgag gattttttgc atactgtctc
      121 tactatactt aggtcactaa gaaaaaggag tgatttatta tgaaaaagaa catgattggg
      181 acattattac tttcaacact tcttctaggc ggcttggcaa caccagcttt tgctgagggt
      241 caagcgactt caaaaggaga tattaccttt actgaaccaa caaataccgt ggagcctctt
      301 aaccctactg atccttcaaa accagtagag ccagcagatc cggaaaatcc agcaactggc
      361 cagacaggtc ctttaacact ggatgtagtt cccgaattgc catttggtac acacgagatt
      421 gaaagcggaa caaaaacgta tcaagtagac gcttcaaaaa acgatacacc ttatctccaa
      481 gtatcagatc gtcgaggtgt aggtgcagat ggccaagcac aagggtggaa cgtgacagtt
      541 tcggtttcag attttgtaaa cggttcacaa gttttgcaag gcgctgaatt agattttgga
      601 acatccactg ttaaaagtac gtcagataac gaatccactg gaccaactag tcaaactgta
      661 actgggttga gtaaagcaag tgcagcgaca ccaatattta cagcagcaaa agatcaaggt
      721 ctgggaacat ggctttctgt ttatgatcca gcaaatatca cactgaaagt gccgaaagca
      781 gcagctggaa cattcacggc tgatttgact tggaacctcg tggctggccc agtagcatag
      841 agtatgaaat aaattcaaca aactgcggtg aaaatactat aggtgaagga ttttttaccg
      901 cagttgttgt tgaaaggatg tggtggacaa tgaatcaaag taaacgactg tttgtttcgt
      961 ttttttctat tttaagtcta tttttcattt ttccgtcaat cagccaagca aaggattcag
     1021 caggagactt tggaatcaaa ccggtatttc cagagaacca aatagataaa gcaatcggtt
     1081 attttgattt attagtggca ccggaacaaa atcagacact agaagtaatt atcagcaatt
     1141 cttcagatga agaacgaaca tttgaggtct ctgtcaatcc ggcggtaacg agtgatggtg
     1201 gaacgatcga ttatagtcaa aaaaacccaa cgttagatga gacattgccg tttgatgtcc
     1261 gtgacgtttt gctcattgcg aaaaaggaaa tcaatgtatc agcacatgca gaaacaactg
     1321 tacctataga agtgaaaatc ccagcaaaaa gctttaaggg acgtgtatta gcgggtattc
     1381 atgtttcacc taaagaagaa gctgaaacag aaaatgctac agaaggagca caaatcaaaa
     1441 atcgtattgc ttataatctc gcagtcgttt tacaagaaag tcaagagacg atagaaccgg
     1501 atctgaaact tttatcagga gatttggacg aggtcaacgc aaagccaact gttcagcttc
     1561 gtttccaaaa tcctcagcct aggattatca gcaatttgat atttacgagc aagatctttt
     1621 atgaaaatca gctttatatt gaaaatacgt ctaatgcatt tttagttgca ccaaattcga
     1681 attttcactt gaatcttgat ttagctggtg ataaagcaaa agccggcgat taccgcgcag
     1741 aaatcatagc aaaatcaggc gacagtaatg aatggcgatt tacacaaaac tttacgatca
     1801 aaaaagaaaa agcacaaaaa gtaaatgaaa attccgtttt tgcagtacaa gaacaatctt
     1861 tcccatggct ttatgcagga ttggttgctg cagttctagt gttatggttg attttgctgt
     1921 ttttgtgggt ccacaagaaa aagaaaaaag gagaaacaac atgatgaggt gatttcgttg
     1981 aaaacatcga tcttattggg agggattatt gcaagtttgc tgttcttcag ctggcaagag
     2041 ccagtccaag cagataccaa aagttcaggt acgattacat tttatgatct aagtccaatt
     2101 ccgcatccaa gtggttcagt caatggcgca tcaaaacagc agacacagct accgatttat
     2161 aaagaatcta atcaacatgg cgtattcccg gagacgaatg aacaaaagat ccgttttctt
     2221 tatttgatca ttggtataga attatggctt cttgcgtggt tgttgttatg gagaagaaag
     2281 gaaaaggagg atgaacatgt tgctacaaaa taaattttca ttttttcgct ccttcttttt
     2341 tacttcgctt tttgttttaa gtatatttat cttttcacct tcggcagaag ctgttggagc
     2401 aacgcctcct gccatttctt atgatccata cacgtatgaa aatatcgtac ctccaaatgg
     2461 tggacgtagt gcagtcaatg gcgggaagct tgtccaacta actggggcta accaattgcc
     2521 taaattgact gctacttatt tgaacgatgg ttcaaatgat ccttggaaag gtggcacggt
     2581 ccgttttcat tgggaaagcc atgtgaaact aacaaatgta cttgatttgg tgaatatcac
     2641 tgcacaagga tttgcatttg tggcgatcat caatttgccg gaacatgtat caagcagtga
     2701 tgtattaaaa gcaattgact ggaacaacgc ctacttgtat attgccggtg cccccatcaa
     2761 ggttactagc ggaagtttat tatcagcagg aagccatacc ttgcgttttg ggatggggtc
     2821 gtgggataca aatactctat tgacagatat tattgctatt attacgcgag gcgaattcaa
     2881 cgtggacgat atcccgcttc aatttgatgt tacagctaat gtcgcgaaga tgacagaaaa
     2941 cggagataaa tatgatacga gtccaaacaa aattttgacc aagggtaaat tacaaccttc
     3001 tatgtctaaa aaggccgttt tttctgttga tttttatgat tcgaataata ttatccaaga
     3061 tcgtatgttc aattcgattt tagctccagc tgcaggtaga ttttatccta aattaactgg
     3121 cggaaacttg aatccaggag catatgcatt ttctgcaagt gcagagataa atacgtggaa
     3181 tagttacatc tcaccaagtg attcaacagg aaaatataat acatttgctg ataccacaga
     3241 atacgtggat ggaaataacc agaaccttcc aggctctacc aatagtcgga cattgacgat
     3301 ggggctgact gaaggacgtt ttgatcagtt gccatttagt cgctttgatc gcgtagtcaa
     3361 ctattttaca ggaaaaaacg ttacacaagg agcaatactg actcatactc cagcaagcac
     3421 aagtggattg aatcagacag ccaatatcgt gtacagtggg aaagatgcgc aaggcggatt
     3481 gctttctcct gttgctttaa aggtattgga gcagtacaag ctagacggaa cggttttacc
     3541 aacaaactta acagccgata gtcagtgggg aaagctcctt tcttctgcat cgtaccaagt
     3601 cacggccaat tggtcagcaa ctgaactaaa aaagggttcg atccattaca ggctttattc
     3661 gaaaggaacc caaaaattag cgacaggatg gacagatcaa cttttccaaa cgatccaatc
     3721 aaataacggg ggtgtaaata cagctacttc tacactacct gcattggctt cagggcaata
     3781 ttattttgat tatcgcttgg tggacgatgt acttactaac atgtatccgt cttttgcgta
     3841 caaatggcag tctgaacaag ctggaatcac cactcttcct caaataacag tggctaattt
     3901 tccatctgtg agtgcagata gtcagctaaa aaaccttagc agacaacctg agacaggaga
     3961 tcccctgtct gctctatcag gagatacgat tcaagaaaat gtgacattca cgttaacaaa
     4021 atctggggat gcgataaccg acaaaaaaat cacgatctca cttcctgaaa atactactta
     4081 tatcaatggt tccttaaaat taaatggtac aactatcgca gataccggca ttcaacaagg
     4141 agtttctgtc ccagcagatc tattgagcaa aataggagat accattcatc ttacttacaa
     4201 ctatcaatta aatactgtag atacttcttt acaatccgtc agcatactga caaaggcagc
     4261 tgtactttcc agcaatatta cattagcaga tggtgctaag cttcctaacc cagttgtcca
     4321 aacatctgct aaaacaattc ttgtccccaa acaagaatta acattagtta atgtaccaga
     4381 tgattttaca tttggtaacg atctccccaa accgttgaag acaagttatt atgaatcaaa
     4441 aggcgatttt tcttttgatg tgcgggatac tcggcttcca agcacgtctc cttggcaact
     4501 gacaggtaca ttgacttctt tatttaagaa tgatcaaggt caagaattaa gcggaacaaa
     4561 attatacttc aatcattctg gatcaaagca attgattcag caaggtcaaa acacgttgat
     4621 ttatgagagt gatggaacag ctaaaggaga ggttctcgtt gactttcccg ataccgatgg
     4681 tttactctta gaggtaaata gcagtacgaa tgctcaacct ggcgcaacgt atcaaggcat
     4741 ggtcacatgg gaactgacag ctgggccaac cagctaagtg attagaattt gtatggatct
     4801 gtgataactg tcacagatcc tctttttcaa ggatgagaag gaaacttctg ctgttaaaat
     4861 cagaaatgct tgaaggagtg gacttggaac ttttcagttt gcttgaaaaa aatgaacaac
     4921 ggcaaatcaa acttttccaa cttttattag aggaaaaagg agaggtttcc gttaataacg
     4981 tacttacccg cttatcagtt gatcgggcta ccttgaaaga agatctgttt tatttacaag
     5041 ctaacttgga aaatatcaaa caattggaaa ttgttatcca agaagggaat attttattaa
     5101 tcagacatgg aaatatagca gcagtcgatg tttattatca ttgttacttg cgctattcta
     5161 caaaatatca gatacttctt tatctgttgg aaaatggctc atttgatcgg cagaaacttg
     5221 tcatggaact taatatcagt tcggctactt tgtctcgcag agtgaaggaa ttaaatgatt
     5281 ctttaaatga gtttcatctg aaaataaaaa gcgggcggct gaccggtcca gaaagtcaaa
     5341 ttcgttattt ttatttccaa ttattttggt ttggacgtcc ctatcttgaa aacaaaaaag
     5401 aatacagtga tttatcagga aacacttttt tagatctgct gcaaaaagag tttagttttg
     5461 ctattacaga agaaggacga ttgaaatttg aaatatggct ttccattatg aagaagcgaa
     5521 tgcgctgtac gaaaaaatcc aaaccagatt atagcaatct tcctgttgga ttgtttcaaa
     5581 cgacacaatt tttattggac ctccatacat ttttgacccg ttacttcttt caatatgcct
     5641 ttccttggaa tcaaaatgaa acgttggttt tttatctttt catgatcagt aactttacat
     5701 tagatacaca taactcgcat gtccaggagt ttttgataag cgaaaaatac aaagacgacg
     5761 tagtagctca attgaatcga acgtttaaac aatcgataga agaatatttc tctttttatg
     5821 tttttccaga agagatttcg caaaagattg cgttgacagt gatgcaaaat cacgctcatt
     5881 ttgcctattt tagaggatgg atgaatattt ttggccaaga aggattaaaa cagcggttaa
     5941 ctgaagtaga agataaacaa ttcctggttt tatgtgaaag attggtcaga caaacatttg
     6001 ctattgttga ttttactgaa gtagacgagg aaaatgcccg ctttgaatta tttgctcgct
     6061 atgcatctat tttacggacg ctgatcaagc agttagaatt acgtctgcaa attgcttatg
     6121 atcttcctta tgaaaggcta atggcggata tcgtgaaaga aatcatccag gaacaattgc
     6181 tgaatacgat caaatatgat ttagtcgaat acgagaaaga aaagcagtat gatatcattt
     6241 tgactagcca attgaaagag tacccgtcac agaagtccgc taaagttttt gtattcacta
     6301 gcaacgaata taattatgat ttcccctatt tgaaccaatt tttaaaagaa tgttatttag
     6361 aaaaattgaa tttaaggatg aataaaacat gaaaatcgtg atcattggtg cttcccatga
     6421 aggcatcaca gctgccctaa atctaagaaa acttcaaccg aaagcagaag ttttactgat
     6481 cgatgaagat cataaagatg gactaggcta tgtttcaaat ggaatcaacc tttatttaaa
     6541 aggaaagata cgtagtttag ctgaagttgc ccataacatg cggactcttc aagaaagtgg
     6601 ggcaaaactg atcaccgaat ggagagtaac tgaacttgat ccagacaaac atcagctcat
     6661 cctcgcatcc aaagaaggaa aaaacgagac cataacctat gataaattaa tcgtagcgac
     6721 aggttcctct cctgtcacct tgtataaaca aattgaagct gaaaatgtct acacctataa
     6781 aaatctagtg caatctaagc aagtacttgc cgctttaaaa gaagcaaaag aagtagtgat
     6841 cttcggtgct ggttacattg gattggaatt agcagatgct ttgagaaata aaggatacat
     6901 tattcatcta gttgattata tgccgaatgt tttatcaaga tatttcgata aggatatgat
     6961 caacagtttt caaaatcagc tgcaaactaa gcaaataaat ttttatccaa atgaattctt
     7021 gatcgattgg aaaaaatcag aagagaaagt agtatccgta caacttctgt ctcaaacaat
     7081 aaaggcagat atggtcattt tttctgccca aactcgtcct aatacgacat tgttaaaaga
     7141 aaaagtggct ttgtatgagg atgagactgt gatagtcaat gaatatctgc agacaagtga
     7201 tccggacatc tatgcgattg gagatatcgt cccagtcagt tttgacaaaa ataaacggca
     7261 tctcttttta cctttagtta ctcgagctgt acatatggca agagcagtag cgctaacttt
     7321 gagtggtcag ccaaccgctt acgacctcag acaaaagata acagcagcag tcattataga
     7381 ctacttttta ggaactgtag ggctgacaga agatgaagcg ccattcttgg aacaaaatac
     7441 cggttcgtgt tcaggagaat ttgatctatt tccacaatac gacgaagaaa acaaaacagt
     7501 aaatgcaaag ctgatctacc atccggatac attagaaata attggcggac agctgataag
     7561 ccaagaattc ttattatcag atttgaacct gcttgcggat atcgtgaaac acaaaactac
     7621 gattccacag ctagcagttg aggattttgg atttctgtct gaatacacct ctcgttttca
     7681 ctacctcaat gagttagctt ttaaagtact agctaagaga gcaaatagca atagagtaga
     7741 taaaagactg tgagaaatat cacggtcttt tattgtgtgg ggatataata aatattaatc
     7801 aatcgagaat aaaaaattca tataatgaaa tagcggaaga attttttgag cataatattc
     7861 gccaaaaatt tatcaagtga taaaattgtt gtataaaatg attatttcag gaggaggagt
     7921 taaatgtttt tagcattaaa tgaaattatg cattcaaagt tacgttatgc gttagttgca
     7981 ggggtgatgt ttttgatcgc ctacctggta ttttttttga ctgggttagc ttatggctta
     8041 gctcaagata atcgaacagc agtcgacaag tgggaggcag attcgattgt gctttcgaaa
     8101 gatgcaaatt caaatctagg gatgtccatg attactaaga agatagcaga agaagtcgaa
     8161 ggtgggaaag tggcgtatct tgcccaaaca cctggagtcg tgactagtaa agacagtaca
     8221 gaagaaggaa aaatcaatgt tagcttcttc ggtatcgata aaaatcaatt catcatgccc
     8281 aatcttgttg aaggaaaagc ttttgataac gatgatgagg cagtaggcga tattagtttg
     8341 aaagaagaat atggtctagc cataggagat acagttaagt tatctggtag tgacaagacg
     8401 tttaaactaa ctggctttac ggatcatgcc aaattcaatg tctcaccagt tctctataca
     8461 accatcaatg cttaccaaga aatccgcttc gaaaaagaag atacaagtga aaatgcacgg
     8521 attaacgcaa tagttgtcag aggtaaaatc agtaatttac ctgaagattt agaacagatc
     8581 aaaatttcta aattcatcaa tgaattacct ggatataatg cgcaagtatt gacttttgga
     8641 tttatgatcg gatttttgat cgttattgcg gctattgtga tcgggatttt catttatgta
     8701 ctgacgatgc aaaagattaa tatctttggt gtaatgaaag cacaagggat cacaggagga
     8761 tttattgcgc gttctgtagt ggcacaaaca ttcattttat catttgttgg tattcttctt
     8821 ggtctattag gaacagtggg aacatccctt gttctacctg atgcggttcc attccaaagc
     8881 aattggctgt tttttggcgt cattagcttg ttgatgttag tagtagctgt gttaggcgca
     8941 ctattttctg ttcggacaat cgtaaaaatc gatccgttga aggcaattgg ataagaagga
     9001 ggaagaacat gaaagcaata gaatttaaag aagtagaaaa aagtttccaa gatggcgacc
     9061 aagtagttaa agcattgaaa gaaacaacca tgagtatcga taaaggggaa tttgttgcaa
     9121 tcatcggtcc ttctggttca ggtaaaagta cttttttgac tttggcaggc ggattgcaga
     9181 cgcctagcag tggctctgta tttatcaatg atcaagaatt cagtaatcaa aaagaaagcg
     9241 aacgcgttaa actacgtttt aaagaaattg gctttatttt gcaagcttcc aatctggttc
     9301 cttttctgac agtaaaaaag cagttattat tagtagataa gattaaacat gaacatcgtc
     9361 aaaaagaagc aaacgaatta tttgagcagc ttggcgtgga taagttgatc aacaagtatc
     9421 cagaagaact atctggtgga gaacggcaaa gggtcgcaat cgctcgtgca ttgtacaatg
     9481 atccgtccat tattctagca gatgaaccaa ctgctagttt ggattcagaa aaggcacgag
     9541 aagtagtcga tatcttggca aaagaatcaa aagacaaaaa taaagcaacg atcatggtta
     9601 ctcacgatac acggctgatt gacaaatgcg atagaatatt tatgatggaa gatggtgtat
     9661 tgaaagaaaa agaataacca aaaagcaggt ggaaaaatgg tccatcgata caacaaagat
     9721 acacagcaaa aaattttgaa agaagcgact gacttgttta tgtccaaggg atatctcggc
     9781 acttcaacaa gagaaatcgc acaaaaagtt gggatcaccc agcccaatct ctatcattat
     9841 ttcggtgata aagaaaaact atatacggca gttttagaaa accacttaaa agatgttgga
     9901 aaagctttga gagaaatcgt tcaaacaagc gaaacgggat ttcaagtaac cttgacaaaa
     9961 atggcgcagt ttttgattga gacacatctg gtcgatttgt ttctgatgct tcacgatctt
    10021 gaaagcaatc tttcaaagga aacaagagat catcttttct ttctatggaa gaaaaattat
    10081 cgtgaacctt ttgaagaaat cttttcagca aaccaatctg tgctaagaaa tgggatttca
    10141 aaagaaatcg cagcaaggca ttttttctta gtgttagcac cttacatcac tcggtcgaaa
    10201 agacctgtgg aagaaccgct aaatgtggcg caattgatcg atttatattt gaatggtgta
    10261 ttaggagaag cgtaaagctg ttatataggg agaaaatagt taggtgaaga agcaagatat
    10321 gacgaagatc gttatatctt gcttctttat ataggtagtt tttcataaat acaaatttgt
    10381 tattctctca tgattatcag ggtatatttt tatttattat gtcggtgttc caggaagtgt
    10441 tttaatttaa taacgaagaa attaattgtt tgtagaatga aggaaactat ttattgggta
    10501 gatgaatcac cacgaatagt caaaaggaga tttcaggata tgccaaaaat gaaaaaaatc
    10561 attttagcag taatgttatt ttctacggtt atatctttta cagccccttt tttgcttact
    10621 taagctgatt ttaagttttg gcccttagtc tggatctacg aggtgagagt caagaatgaa
    10681 aaaaataatt ggagcttttg tatttgcaat cattatcatt attatctgtt ttcaaataga
    10741 tgtttttggt caaaaaaaga tagttggaca aacggtcagc agtacgaaca gtacggttac
    10801 aaagacaaag gaatcatttg atgatacaga acaagagaca ttaatcaaaa tcggaaaaaa
    10861 tgaccgtaca ctatatacag atgactcgct aactacccca cttgcaacta taaacggcgg
    10921 agagctggcg gagtttcttt ctgaaacaaa aaatgcttat cagatcaaga caaatgatgg
    10981 ctatactgga tatttagccc tcgaagatgg aaccaaagtc acaaagaata tacaaacaaa
    11041 accggaagag ctatctgatg cagtgattgt attagatcct gggcatggcg gaaatgatac
    11101 tggggcatta agcaatgatg aacaaacaga agaaaaagat ataacattaa gtacagccat
    11161 aaaagtaaaa aaggcgctag aggatgctgg agcaacggtt tatttgaccc atactacaga
    11221 tgaattagta cagcttggag atatatgcga ctacagtgaa gaaaaaaagg cagatgtctt
    11281 tatcagttta cacgcagact ctacggaata tgcgaatgaa gcaactggaa tcacgacata
    11341 ttattactat ggacaagagg aaacattagc acagacaatt gctgactcct tcactgatct
    11401 gcctctggat tcaagaggaa tctccactgg gaactatcaa gttcttcgag aaaatcttca
    11461 accttctatt ttaatcgaga tgggttatat gaataatgat agtgatttaa aggaattagt
    11521 aacagacagt tatcagcagc agattgctgc aagtttgaca caagcattga ccacttattt
    11581 tcagtaataa ataagcccag ccaaacaaaa atagctcctc atatttttcg tttggccggg
    11641 cttattatcg cagatgcaag cttttaaaca ccgtttaagg aagaggtcgt gagcctgccg
    11701 ttcaactctg agtcacaagg agcaatttca aaaaacagct tctcatgttt gatgactatt
    11761 gtgacttgtg accgaggagt tggcatgaga acaccgttta agaaaaaggt tgtgaaatca
    11821 acgttttgtt ctgagtatta gagaaacaaa cggaaaaata gttcctcata ttttgccgtt
    11881 tgttgagcta ataccgagga tcagatgatt gaacaccgtt tattcggaac aagggactgt
    11941 gacatgactt ttgtcacagt tccattattt ttttagtagc ttcaaagctt tttctgtatt
    12001 ggcaaaatga agtttggcat atttttcaag cataggcatg ccgcctttct ccaatagttt
    12061 tgccgctact tggtcagatt tcgttccagc tcctgacgga agggtgattc cagcttcagc
    12121 tgatgctttg tctaactctt ccaaaaagct ggcacgactg atgatagaag cagcagcaac
    12181 agctaaatga tattgttctc ctttagtaac gaagtacagt ttttcttgta attgattttt
    12241 ttctaaacgc gcatattttt taaaatttgc ttccggcgta aactgatcga tcaaaatcgc
    12301 ttctggtttt tctggctcga ttttttttag cagcaaatgg atcgcttgat tgtgcaaagc
    12361 gactttcatc cgaacggcat tgtattttgg ttggatctca ttgtattttt ctggagataa
    12421 gacaagcagt ttatagggga tggttttttt taagatgtca gcaagctgga tgatttggct
    12481 atcttttaac tcttttgaat ctctaacacc aagtttacgt aattctgcaa gctgatcacg
    12541 tttcacataa gcagcacata ctgttagcgg accgaaatag ctgccatttc cgacctcatc
    12601 actacctaaa acggataatt gactgatatt ttttggcaaa gaagaggctg tttttgctgg
    12661 cttggcttgt ttatcctgtg cctcccccca tttatcagct tctattgctg cattcgtacc
    12721 ttgaaacatc acttttccgg atgtataagc ggtaatggtc gtcccgtctt tttttgcagc
    12781 aaagctagta taaggaatct gtttatttaa caaataagag cgatagtatg ctttcatttg
    12841 actaagttgg tcgtttgttg ctttgataat gacgttgctc ataaaattct cctcgttttt
    12901 atacataaaa ctataccgca actcacgact tttcgttttc taagagattg cgagacatag
    12961 cattttttta aagtttatca tataatagtt aagtatgtga aaaatatttg tggagaacgg
    13021 tgaaagaacc aacttcatgg tacactaaat aaaactttca tcaaatagga ggaaatgatt
    13081 cgtatggcgc acgaaaaaac acgctacaaa gcggtgattg ccaaccaaac atatactatt
    13141 atcggacggg aaaccaagca tcatatggat atcgtaacga agctgatcaa tgaacagtta
    13201 gcagaattga aacaattatc accacaaatg gataatgaac aagcagcaat cttgatggct
    13261 gtcaatgcgc tttcggatca attgaagaaa caagaaagaa tattggagct ggaagaagaa
    13321 acagcagaat taaagaaaaa aatgatcaaa tttacagagc ttgaaaatcg tgtgaaacgc
    13381 attgaagcaa tcgagaacga agctcgggaa gtattgaaag aaaatggtca agcagatcat
    13441 accattaaaa atcatgtgga agcacaacag attttaaacg agaaacgaaa aggacaaatt
    13501 aaacaaaaat cttctaatta agatcctttt atcaaaataa gaaaaattta aaaaagttag
    13561 aagagaaagg aacgtagcat gctgagtttg ctgattttat ttttattgct aattgcgttt
    13621 ttttctggag cacgtcgcgg gtttgctttg caaatcatat tcgcgattgg atatgtattg
    13681 tcatttattg ctgcccagca tttttacaaa ccattagcaa gtcatttgga attatacatt
    13741 ccatacccag ctgtcacccc aacatcaaag ttagcatttt ttgatcaggt atttgccttt
    13801 cacctagatg aagcttttta tgcaggaact gcttttctga ttattttgct aattggctgg
    13861 ctgcttaccc gatttgtggg ggtttttgtc catggattga cgtatgtgcc gatcttgaga
    13921 caggtagact ggattgcagg aggcatcctg tcactaatca tggcttacgt tactatattt
    13981 ttgattttgc agttacttgc ctttgttcca ttagatgtgg tccaaaatca attcggcgag
    14041 catagtttcg ctcgttttat cgttgagaga acgccatttc ttaccaacaa gatgtatgag
    14101 ctttgggtaa cgaatatttt gaattaagga aaatagtgct ggaaaatatt tcgttttttg
    14161 tacagagtag tttatttaag aaggctgcgt agcgtatgtc cggcacagct cttttttcat
    14221 agtgaaagat aaggtgataa aatgaataac cgaatccttg aaacattgga atttgaaaaa
    14281 gtcaaacaga tggtcagaca atttgtagtg actgcacaag gaaaagaaga actggcagaa
    14341 ttggtaccag tgagtgagaa acaaacgatc acaaactggc ttcaagaaac tgaggatgga
    14401 ttgaaagtgc aacgtctgcg aggcgggatc cctataccta aaattgaaaa tatccgtccc
    14461 catatgaaac ggattgagat cggagcagac ttgaatggag tggagcttgc acaagtttcc
    14521 agagtattgt ctacgacaag cgaattgaat cgtttcattg atgatctttc tgacagtgaa
    14581 atcgaatttg cacgtttgta tatgtgggca gatcagttag tcacgatccc tgttttgagc
    14641 cgccgtttaa aggaagcaat cgatgaagac ggacgcgtga ctgatgacgc ttctcctgag
    14701 ttaaagagca taagacagaa cattcggcga agtgaacaag ctgttcgtga acagttagat
    14761 gggatcgtcc gtgggaaaaa tgcaaagtat ttaagtgatg cgatcatcac catgcgaaat
    14821 gaccgctacg ttatcccagt caaacaagaa taccgcggtg tatttggcgg tgtagtccac
    14881 gatcaaagtg cttcaggtca gactttattt attgaaccaa aacaagtggt ggatttgaat
    14941 aatcgtttgc gtcaatacca aatcgctgaa cgaaatgaga ttcaacgtat tttaagtgaa
    15001 ctttctgctg aacttgttcc ccatcgtcaa gaaatcatcc acaatactta tgtgattggt
    15061 aaaatggatc tgatgaatgc aaaagcacga tttggtaaag aagtaaaagc catcgtgccg
    15121 ggaatcagtg aagacaatca tgtcgtcttg aaacaagcaa gacatccact gatcgatcag
    15181 gaaaaagtag tttctaatga catcacaatc ggaaaagact atcaagccat cgtcattaca
    15241 ggacctaaca caggtgggaa aacgatcacg ttgaagactt taggtctgtt acaactgatg
    15301 gggcaagcag gattaccgat tcctgcaggt gaagaaagtc aaatcggtat ttttgaggaa
    15361 gtatttgcgg atataggaga cgaacagtcg attgagcaaa gtctatcgac cttttcttct
    15421 catatgacga acactgtaga tattttatca aaagtcaatg aaaaaagtct ggtattattt
    15481 gacgagctcg gtgcaggaac agatccgcaa gaaggtgctg ctctagcaat cgcaatctta
    15541 gatgatcttg gtaaaaagtc tgcttatgtg atggcaacaa cgcattatcc tgaattgaaa
    15601 gtttatggat ataatcgggc aaatacgatt aatgccagca tggagtttga tgtggataca
    15661 ttaagtccaa cgtatcgttt gctgattggc gttcctggac gaagcaatgc gtttgaaatc
    15721 tctagccgat taggtcttga tacagaagtt attgatgaag cgaagcagtt gatgaatgat
    15781 gagagccaag atttaaacga aatgatcaca gatttagaga atcgccggaa aatggcagag
    15841 accgaatatc tggaaatgcg tcattttgtt tctgaggcac aagaacttca cgatgatttg
    15901 aaagaagctt acagctattt ctttgaagaa cgtgaaaaag aaatggaaaa agcaaagaaa
    15961 aaagcaaatg aagtcgtgtc agaggcggaa gaaaaagcag aaaaaatcat tgctgatatt
    16021 cgtaaaatgc aacagcagat tgggcaagga aatgtgaaag agcatcagtt gatcgatgca
    16081 aagacccaat tagcaaatct acatcaagaa gaaactttga agaaaaataa agtattgaag
    16141 aaggcgaaag aacaaaaaac gttgaaaccg ggagacgaag tgttggttac gacttacggc
    16201 caaagaggga cgcttttacg taaaaacggg aatcagtggc aagtagaaat cggtatatta
    16261 aaaatgaatg tgtccgaaga cgagctgacg cctgttgctc ctcaaaaaga gccgacacaa
    16321 cgagttatcc atgctgtacg atctgaatct agtagtcacg tgccgaatca attggacctt
    16381 cgaggaaaac gatacgaaga agcgctaagt gaggtagatc aatatttgga ttctgccatt
    16441 ctagctggtt atcctcaagt gactattgtc cacggaaaag gaacaggcgc acttcgcaag
    16501 ggaattactg attatcttaa aaaccatcgg agcgtcaaaa gctttgagtt tgcaccggca
    16561 aaccaaggcg gaaatggtgc gacaattgtt aaatttaagt aaagcttact aaaggtaagc
    16621 agatggttcg ctatccaagt atagaaatgc tatactagtc atagatttta aaaatggagg
    16681 tctttgatat gtcacaagta attacagata agacatttaa tgaagaaaca gataaaggac
    16741 ttgtattgat tgatttttgg gcaacttggt gtggtccatg tcgtatgcaa gcaccgattt
    16801 tggatcagtt ggaacaagaa tatgatgaag aagaattcag aattgctaaa atggatgtgg
    16861 atgaaaatcc agaaactcct caacaattcg gtatcatgag cattccaaca ttaatgttga
    16921 aaaaagatgg tcaagtagta gaaaaagctg ttggtgttca ttcaaaagaa caactacgtc
    16981 aaatgataga tcaatattta taaaaactta cagcaaaaat aagctgaggg tgggactgaa
    17041 tccagttccg tcctcggttt ttttgcggtt gagttaaggt tattcaaatt aatatttttt
    17101 gagtataatt acgttgtcag gctggattgt ttttttgaca gacatgctat aataacttta
    17161 attgaatatg aaggggagta ccagatgaac gaacgaatca aaaacaaatt agctttactt
    17221 cctgatcagc ccggctgtta cttgatgaaa gataaaaatg gaacgatcat ttatgtcggc
    17281 aaagccaaaa tattaaaaaa tcgtgtccgc tcatatttta ctggtagcca taatacgaaa
    17341 acggaacggc ttgttagtga aatcgaagac tttgaataca tcgttacaga atcgaatatc
    17401 gaagcattgc tcttagagat caatctgata aagaaaaatg atcctaaata caacattatg
    17461 ttaaaggatg ataaaaccta tcctttcctt aagataacga atgaaaaata tccccgtttg
    17521 gtgattactc gtaaggtact aaaagacaaa gcactgtatt ttggaccata tcccgatgtc
    17581 ggtgcggcga atgagacaaa gaagatcctc gatcgattat ttcctctgag aaaatgcaaa
    17641 cctagtcaga cgaaggagcc ttgtctttac tatcatttgg gacaatgcct gtgtccttat
    17701 tatttcgacg tagatccgaa agtctatacg aaaatcgttg atgaagtgaa aaacttttta
    17761 aacggaggac acgaaaaaat cgagtcagag atccatcaga aaatggaaaa agctgctgaa
    17821 aacatggagt ttgaaaaagc tgcagaatac cgagaccaga tccgtgccat tgagacaatc
    17881 atgactcgcc aaaaaatgac aaatactgat ttactggatc gagatgtatt tggttatgcg
    17941 attgataaag gatggatgtg tgtccaagtg tttttcgtaa gacaaggaaa gctaattgaa
    18001 cgagatgttt caatgtttcc tttctataac gaagcagaag aagatttctt gacttacctc
    18061 ggtcagtttt atcaggaaaa tgagcatttc attcctaaag aagtcttgat tcctgatacg
    18121 atcgacaagc ccagtgtaga agctttgtta gctacgaaag tgctgcaacc aaaacgagga
    18181 gaaaagaaaa aattagttga attggcgagt aagaatgcct cagttgcttt gaatgaacgg
    18241 tttgatctga ttgccagaaa acaggaacgg acgatcggag cagttgaacg tttaggaaac
    18301 gcgatgaata tcccgacccc aatacgtatc gagtcttttg ataactctaa tatcatgggg
    18361 acgaatcctg tggctgcgat ggtcgtattc attgatggaa aaccggcaag aaaagaatat
    18421 cggaaatata aaataaaaac agtcaacgga ccggatgatt atgcatcaat gagagaagtc
    18481 atctatcgca gatattcgcg agtgattcgc gaagggttgc ctttacctga tttgatcttg
    18541 atcgatggag gaaaaggaca agtagatgtg gcaaaagatg tcttagaaaa tcaattagga
    18601 atcgatattc ctattgctgg catggtaaaa aacgataaac ataaaacaaa tgagttgcta
    18661 ttcggtacag atttggctgt agtaccgctt gagcgaaatt caccagagtt tttcttactc
    18721 cagcgaatcc aagatgaagt ccatcgattc gcaatcactt tccatcggca gctacgcagt
    18781 aaaaacagtt ttgcttcccg attagatgaa attgaagggt taggaccaaa acgaaaaaaa
    18841 atgctgctta aagagttcaa atcgttgaaa aatatcacag cagccacgac agaagaatta
    18901 caagaaatcg gactgccgaa aaatgtcgca caaaacgtat ttgataaatt acatcaggaa
    18961 tgaggaaagg gcactttaca aagaaagtaa agtgtcctat cattttatgt acaacaaaaa
    19021 gagcgtttac gttttgttgg taaataataa atcgcttacg tctggtgtct aaggatatat
    19081 gtgatttctt gaagaaggag tgaagaaatg ttagaagtca aggatcttgt taaaactttt
    19141 gggaactaca cagctgtcga tcatgtctct ttccaaatcc ccgatggaaa aatcatgggg
    19201 ctaattggcc aaaacggggc tgggaagaca acgacttttc gtttgatctt ggattttttg
    19261 acacaagacc aaggagaagt gttatggaat ggccatcatc ttggggagaa agattatgat
    19321 gtcatcggtt atcttccgga ggaacgggga ctttatccga aagtaacgat tcaagaccaa
    19381 ctgctttatt ttgcagaact tagagggaaa tcaagaaaag agattgaacc aaaaatcgac
    19441 ttttggatgg aaaaatttca ggtaaaaggg aaaaagacgg ataaagtaaa atctttgtct
    19501 aaaggaaatc agcaaaaagt ccagctgatc gccacgttaa tccatgaacc taaattgatc
    19561 attttggatg agccattcag cgggttagat ccggtaaatg ctgaattgct aaaagatgga
    19621 atattggaat tgaaaaaaca tggttcatgt gtcatttttt ctagccacaa tatggataat
    19681 gtagaaaaaa tctgcgatca tttgatcatg ttgcgaaacg gaaaaatggt tttgaatgga
    19741 aaagtacatg agattcgtga atcatttggc cgtacgaagt tattcttgga atctggttta
    19801 agccaacagg aagtagaaga aatcgaaggc gtgaaaaaag tgatccttca tgaagacaat
    19861 acgttagaga ttaccttaga agatcctgaa gctgggaaag aaatctttac tcgtgcgact
    19921 cagttcggct acattcctat gtttaaccag caaccgccaa ctttggaaga gattttcaaa
    19981 ttgaaagcag gtgaaatcga tgcgtaagtt ttggattatt accaaagatg tctatttaaa
    20041 aaatgttaag tcgatttctt tcttgatcat gatattagtc ccttttatca tgctgggtat
    20101 catttatgta gcaggaaact ttgctcaaca aaatagtgat gtcaataaaa tcggcgtatt
    20161 ggctgataat gagcaaatca gtcagcaaat gagccaagtc aaaacagatg attttgagtt
    20221 caaagcagtt gattctgaag aaaaagcaca aaaagagctt tcggaagaaa aaatcgatgc
    20281 gtatttagta gtctcaactg agaatgataa gataaatggg atgctttata gcgaaaattc
    20341 attaggacaa agtacacaac tactgataca acaacaactg actggcttgc aatcgatgct
    20401 tcgagcgagt caattaggca tttcaccaga agaagtagct agcttgagcc aacaagcaag
    20461 tttgactcga caaaaagtca attttgattc aaaaggaaaa atgacagtcg gagaagataa
    20521 ctcgacagtc caatacgtcg taagttatgt agcaacgatt gtcttgttca ttattatttt
    20581 gacgtatgcg cagatcattg cacaagagat cgcttctgaa aaaggcacgc ggatcatgga
    20641 agtgatcctg tccagtacga ctgcacaaaa gcatttttac ggaaaattaa caggtgtttt
    20701 acttgttgca ttaacgcaaa tggcattata cggtattatt tttggtatag gatacagtca
    20761 attcaaagat atggaaatgg tcaaaaatat attagacggt atctcattgg ataacttgat
    20821 tggaccattc ttgtggtatt ctcttctatt catgatcttt ggcattttga ttttttctgt
    20881 tttagcagct ttatgtggct ctttggtcaa caaagcagaa gatacagcaa aagcaatttt
    20941 gccagtgact tatctatctc taggcggata catgcttgga ttgatactag gagcttcaga
    21001 tccaaacaat atcgttattc ggatcacttc gtatattcca ttcttatctt catatattat
    21061 gccgattcgc ttagcaaatg agacagtcgg tatgggtgga gcattgattt ccttgttggt
    21121 acttgtagcc gtaacattct tattgatgat cttgtctgca aacatgtaca aatcgaatgt
    21181 actcgtttat agcgaaggcg gattatggag ttcattgaaa caatcgattt caattatgag
    21241 gaatgaacga aaaaaagcat aaaacaatcc taaaatacag aaggaagctg gacatctatt
    21301 gttcccagct tctttttgta tagacctatt ttatttattt tactatattg gatatatatt
    21361 cattgaaaat agtgtataac aactttataa tattgagtat accaattttt ggaggcgttt
    21421 taatggaccg ttatttagat ttactttcag aaaaattccc ctcaacggag gatgtcatca
    21481 cggaaatcat caatctcgaa gcaattttgc agcttccaaa aggaacagag ttatttttga
    21541 gtgatataca tggcgaattt cctgcttttg atcatattct gcgtatcggt tcaggaaatc
    21601 ttaaagaaaa gatcaaagac cttttttctg aacaaatgac ggaaacggat atcagccaat
    21661 tcactatttt tacggcttat ccagaatatg cattaacgac tgattggtac aaagaacaag
    21721 ataaatcgca gctgatccat catttgatcg atcttttacg gtttacgaca gtcaaatata
    21781 cccggtcaaa agttcgaaaa ggattgccga aagaatatag ctatatcatt gaggaactct
    21841 tgtatatcga tgaccgtatc aatggaaaaa aagactatgt aaaaaaaatc attgaacaac
    21901 ttgttttgat gaaggaagaa gaaaaatttt taacgaaact tgcacagacg atccaaaaat
    21961 ctgtcatcga tcatttgcat atcgttggag atatttttga ccgaggaact caagcagcca
    22021 aagtgatgga tcgaatcatg gatttttctt ctgtagatat ccaatgggga aatcatgata
    22081 ttttgtggat tggtgcgtat tgcggctctg aggcatgttt actgacactt ttacggattg
    22141 cagcacgcta taattattta tttgaattag agaaagaata tgggttgaat ttacgtccat
    22201 tgttttcttt tgctcatcaa acttatcaga agaatccagt atttgcgcct aaaaacagta
    22261 aaaatctatc cgaaagagag caagaagaat tagaaaaaat ccatcaggca ctttctatcc
    22321 ttcaattcaa atcagaacat cagttattgg atcgtcgacc tgaatttaaa atggacgatc
    22381 gtaaattgct ggaaaaaatc gactatgaag catcaacgat tgatttagaa ggtcagctct
    22441 atgagttgaa aggaacttgt tttcaaacga tccagccaga tgatccaaaa aaattcttgg
    22501 aagaggaaca aaaagtgatt gatagtttga tgtattcatt ccagcactct ttgagaatgc
    22561 aaaaacatat gacgtttttg atcgaaaaag ggggaatgta tctcacgaac aatcagcatg
    22621 tgctgtttca tggctgtata cctgtagacg agaagggaca gctcttagca tttgaattag
    22681 accaatctta tcgcggaaaa gaactgctgg gcttttttga aaaacagata actgaaagcg
    22741 caaaagatct gactgcaaaa gaagatttag caaccgattt gatttggtat gcgtggagtg
    22801 ggccattttc gcctttattc ggcaagagta aaatggcgac ttttgaacgt tattttctca
    22861 cagagcctca tacgcacgtc gagaaaagca atccttatta tcacttgcga gatgaagagt
    22921 ggttcagtga aaaaatttta gcagaattcg acacaaaaga agaagggtca gcaatcatta
    22981 atgggcacac gccagtaaaa gtaaaaaaag gggagtcacc gatcaaagca aatggaaaag
    23041 tatttgtcat tgacggaggt ttatccaaag cttatcaaaa aacgacagga attgccggtt
    23101 attcactatt atgcaattct tatggtttcc aaatcgtgac acattatccg tttttgccta
    23161 ttgaacaaca atttgcaaaa aaatccgacc aaacaaatgt gaaaaaagta atcgaacagc
    23221 aactaccacg caaactcaat cgtgatacaa caaaaggtat ggaactgcag cagcagatta
    23281 cccagctcaa aaggctgttg gactatcgaa aggacgattg agaagaattc cagtgaacat
    23341 tgttccatag actggagact gagacaaaag tcgtgtcgca gtctcttttt ccggataaac
    23401 ggtgttcttc tgccaactcc tcggtcacaa gtcacactat tcaacaaaca tgaaaagctg
    23461 ttttttgaaa ttgctccttg tgactcagag ttgaacggca ggctcacgac ctcttggtat
    23521 aaacggtgtt caaaagccag tttctcggta ttaagccaaa tttatgcaaa aatgtgaaaa
    23581 gccattttca caaaattttt cttaatactc gaaactaaac agctttttca caaccccctc
    23641 agaaagtcta ttaaaattca ttcacaaaga aatcgaataa gcgctgttca gatggatgta
    23701 cacggtgggt aagttccgga tgccattgaa caccgaggat tttatgcata tcatctttgc
    23761 tttgaaccgc ttcaacgagt ccatcgttag aaaaagcgat ggcttttaat aaaggtgaaa
    23821 gatctttgac tgcctgatga tggtaagaat tcacaaaata tggatcgggg agaaggttgc
    23881 ttaacaaact gtctgaaaca atcttgactt cgtgagtcgt aaattgcggg gcagtgggct
    23941 gttgttcatg ttttactgac cactttggat ataatgaaag atcttgataa agtgtacctt
    24001 ccaaaacgac attcaatagt tggagtcccc ggcagactgc aaaaattggt tttctttgtt
    24061 tcaatgcttc caagatcagt gcctgttcaa attggtctcg ttgaatattt gtttccgtta
    24121 gctttggatg aggatcttcc atgtaaagtt gtggactgac atcttgacca cctgcaagaa
    24181 taagtttgtc gatttgtcca atcagttgag gagctgaatc tggagacatg actggcagaa
    24241 taagaggcaa tccttgagca tctaaaactg catccacgaa tccttgcggt gtatagctca
    24301 cttgatttcc ttggaaagta tctgttgctc gaatcagttg atttccggca atgccgatga
    24361 ttggtttcat ttgtattccc cctaaagtag acttattgta acaaggattt aaaaaaaatt
    24421 aaactatgta agacttgccc ctatacttat ctgttcttgc tgtgttacta tctgtaaaga
    24481 gaaatttcgt gtgaaattca tgacgatagt tgaaaatatt gcttaatttg ttataataaa
    24541 aagtaagcag aaataaaaag gttgggcgta agcttcaagg atctagttct tcaaggggtg
    24601 agaaggacat tttattgaag gggcctgcct atactaagtt atctttagag gtacatactt
    24661 tcaatgaaaa aagaaagcat gtacctcttt ttttaaacga aaggaagtga agcaagtgtt
    24721 agaagctttg gaacaaatcc gaaaagcaga agaagaaaat gaaaagcgtg ctcaaacact
    24781 gcggcagcag ctgaagatct atgcaacaga aaaagagcag gaattggaaa cgatccaaac
    24841 aaactatcga caacaactaa aacagttggt ggaagaaaaa gaacaatttg aaatacaaga
    24901 attagaaaaa gaaaaaatga aattgaaagc agaagcagac aaggtgcaag caactttgaa
    24961 agatcaatat caaaagcatc agagtcaagc gatcggtgcg atcattgaaa gggtgaaaga
    25021 aacttatggc cgtcactaag atggaaaaag tgaccctcat ttcagataaa agaaatcagg
    25081 agaggatttt acaagcagta caaggaatcc aaaacgttga aatccgggat ctgtatcaaa
    25141 atagaacaaa caaccagtgg gtggagaagt attttccaga taccacgatt attgataaag
    25201 aagcaaaatt aagcgcttta ggtaatcggt tgaaagacat ccaagaagct atccaattca
    25261 tacaacacca cggcgatagc cgtcaaaaga aactccattt gaaacgtcaa gaactttcct
    25321 tacaagattt ggaagccaat tattccgaag aaaatttcat aaataaattg aaagaagtcc
    25381 ttgatttaaa agaaaagtgg gaacaactaa ctgaagaacg tgatcgttta gaagaagagg
    25441 aagaatggct tcttcattgg caacagctgg atattgctcc aagtatgtat gcaagtaaga
    25501 cgaccatttt tgagatgggg actgtgagtg cagcaaattt tgaaagtttc aaggaagaac
    25561 tgagtaagct tgatgacgtt tatatggaag aaatagatta tacgccaaaa caagtttatc
    25621 tttcgtatgt tgctttaaaa aaatcagttg ctgttataga agaaattgct gggaaatacg
    25681 ggttcaataa agaaacgtat ccttatgaac aaaatcctaa agaaaaactg caagagacca
    25741 agcagcaatt atccattgtt cacgagcagc aaaagaagat aacgacagcg ttaggtcagt
    25801 gcagtggcta tatccaagaa tttgaatggg tagaagaagt cacacttgcc gttgcagaac
    25861 gagaaaaaat aaaagaacgg tttatccatg cgacttatct gatcgttttg caaggttggg
    25921 tagatgcaga agaaaaacag aatttgctgc atgtgttaaa cgaaaccgta tcagaagaag
    25981 atatatacgt cagtttcgaa acaccaaact cagaagagat tcagcaggaa gtccctacta
    26041 aattgaaaaa ccatccgctt gtcgaacctt ttgaattgct gactgaaatg tacagtctgc
    26101 caaaatatga agaagtagat ccaacacctt ggatgacacc attttatctt gtcttcttcg
    26161 ggatgatggt cgcagatgtt ggttatggtt tgctgatgct cattgggaca atactagctc
    26221 aaaaactact tgttctacca cgcgggatga aacgtttcgt aaaattcttt gagattctct
    26281 cgataccatc gatcatctgg ggattgatct acagttcatt tttcggacag tcattaccaa
    26341 aagaactgtt tggcatccgc ttgcctttcc caatcctatc tacgacggat gacgtcaata
    26401 cgattttgat tttatccgtg attttcggtc tgatacagat tttggttgga ttatttgtgg
    26461 cagcaaagga aaatatcagg agaaaagatt acttgagtgc tgtcagtgat ggatttgcct
    26521 ggcaagggat cctaattggg atcgttattg cgttggttgg tgccatgttg ataaaaaata
    26581 cagcatttgt ttaccttggc gctgggctat cgatcattgc tgccttatgt atcttgatcg
    26641 ttccgattat ccaaacgccg tctaaagtca aaggtgctgc caaaggtgcg tataatcttt
    26701 acggactgac cggctatatc ggtgatttag tcagttatac acgtttgatg gcattgggta
    26761 tttcaggcgg aagtattgga gcggcattca atatgctagt tgctttcatg ccgccagctg
    26821 ctcgattcag tgtagggatc cttttgatca tcgctttaca cgcactgaat atgtttttga
    26881 cactgctaag tgcctatgtc catggcgcac gattgcagta tgtcgaattt tttgggaagt
    26941 tttatacagg aggcggacgt gcctttgatc cgctgaaaac ggcggaaaaa tacgtcaaca
    27001 tcaatcacaa gaaaaaaaac aataaataat tggaggattt ttatataatg atggattact
    27061 taattagtca aaatggtgga atggtatttg cggtattagc gatggcaaca gcgacgattt
    27121 tttcagggat cggttcagct aaaggtgttg gaatgacagg tgaggcagca gcagcattga
    27181 caacaagtca acccgaaaaa ttcgggcagg ctctgattct gcaattgctt ccaggcacgc
    27241 aaggtttgta tggattcgtt attgcctttt tgatttttat caacttagga aatgacatgt
    27301 cagttgtaca aggactgaac tttctaggtg cttctctgcc gattgctttt acaggcttgt
    27361 tttcaggtat tgcccaagga aaagtcgcag cggcaggtat tcaaatttta gcgaaaaaac
    27421 ctgaacatgc tacaaaagga atcatttttg ctgcgatggt tgaaacatac gcgattttag
    27481 gtttcgttat ttccttccta ttagtgttga atgcctaagc ataaaggagg aaaagcagat
    27541 gaacgccatt gaaaaaatca tctctcagat gaacgaagca gcagagcagg aaagagcggc
    27601 gttagaacaa gaagagcgaa tgaagatcga tcaaaacttt gaacaaaaac gtacgcaagt
    27661 tgaaacagaa catcaaaaac aaaaagaaaa acaaatcgaa ttactcgaaa aaaaataccg
    27721 tcagctaagg aatcgccagc aagtagaagt acgacaagaa aatttgaatg cgaagcagga
    27781 atttttaaga cgattgtttg cagatgcggt aactgaaatg gaaaattggg atgaatctga
    27841 acaaatccag tttatcaaaa atgcattgta ttcattacct ttgacaggaa aagtagcatt
    27901 cattgctgga gaaaaatcag cagcctatct ttctcagacg ttgttggatg aatggaacaa
    27961 tgaacttccc tttatgatgg ttttaagtga tgaaactgtt gctgatcaag cgggttttct
    28021 gataaacgat caaggagttc agtataattt tcttttcagc agccttgtac aagatatcca
    28081 aggaacgatg agttttgaga ttgccaatca attattcgaa taaggaggga tcagtgtatg
    28141 gaataccacg aactaaatcc cttgattcgc ggaagagagc ttgaactttt gtccaatgag
    28201 acatttgaac ggatgattca aacaaattct gtcgaagcac ttggtgaaat attgaaatcc
    28261 acgatttaca gtccatatat ttatgacgga tatgaatatg acttcgaaca gaatctttta
    28321 aaggagcaga gccgtctatt tcgctggtta aaggaatcag caccggagcc tgaaatcgtt
    28381 tggatctata cgatgcgtta tactttccat aatctgaagg ttttgacaaa agctgagatg
    28441 acaaatcaaa atctggacca tttgtatatc gacgatggat tttattcatt agaaaccttg
    28501 aaggatgcca ttcatacgca agtttcaaat gaacttcctg aaagcattat ggacagtata
    28561 cgagaagtac gtgattattt tgaagagtct accattcttc agggaattga cgtgatttat
    28621 gatcgacagt ttttgacaga gcagcgacgg cttgccgata agctaggata tcaagaattg
    28681 ctgacagaag tcattgcttt tattgacttg accaatatca caacgatggc tcgaggaata
    28741 ttgcagaaaa gaacatatgg gttcatgacg acggtacttt ccagctcggg aagtatcgaa
    28801 aaagaagtat ttttgaactt tgtagataaa gatatggaag attacacgaa ttttctatta
    28861 gagacagatt atgctgattt tctgcgccct gtcatccgtg agggaaatat tgatctcgta
    28921 aagcttgaac agttgaaaga tgattatcta agttcattgt atcaagaagc acaaacccag
    28981 gctttcggac cactgccact actagccttt ttgaacgcaa aagaggtaga aagcaaaaac
    29041 cttcgtttac tggttatcgg caaaagaagc catttcgaat cagaaacaat cagaaagcgg
    29101 gtgagacaag tctatgacgc ataagatcgg tgtagttggc gacaaagatt ctgttttgcc
    29161 attcaaattg tttggctttg atgttcgtta tggtacaacc aagcaaaccg ttcgtcaggc
    29221 aattgaagaa atggcaaaga atgagtatgg cgtgatttat gtcacagagc aatgtgcagc
    29281 attgagccca gaaacgatcg aacgttacaa ggaacaaatg atacctgcta tcgtattgat
    29341 tcccaatcat caaggatcat tagggatagg gctggaagaa attcaaaaaa acgtagaaaa
    29401 agcagtaggt caaaatatct tatagtatga aaaggagata gaaattttgc aaattggaaa
    29461 aatcataaaa gtctccggac ctcttgtaat ggctgagaac atgtctgatg ccagtatcca
    29521 agacatgtgt ctagtgggag atctaggagt tatcggagaa attatcgaga tgcgtggcga
    29581 tgtggcgtct attcaagtat atgaagagac ttctggaatt ggtccaggcg aaccggttcg
    29641 ctctactggt gaagctttat ctgttgaatt aggaccaggg atcatttcac aaatgtttga
    29701 cggaatccaa cggccattag atacctttat ggaaatcaca caaagtaatt tcttagggcg
    29761 cggagttcaa ttgcccgcat tggaccatga gaaaaaatgg tggttcgaac caacagtaga
    29821 agccggagaa acggtgagtg ctggagatgt tatcgggatc gtagaagaaa caaaagttat
    29881 aaaacataaa atcatggtgc caaatgggat aaaaggaacg atcaaaacaa tcgaaaaagg
    29941 ttcattcact attgatgaaa cagtatgtgt cattgaaacc gaaaatggtg acaaaaattt
    30001 gacgatgctt caaaaatggc cagtaagacg tagtcggcca atcaaagaaa aattaaaccc
    30061 ggatgcaccc atgatcactg gacagcgagt gattgataca ttcttcccag tgacaaaagg
    30121 aggagcagca gctgtacctg gtccttttgg tgcagggaaa acagtcgttc agcatcaaat
    30181 tgcaaaatgg gccgatgtgg acatggttgt ctatgtggga tgtggcgagc gtggaaatga
    30241 gatgacggat gttttaaatg aattccctga attgattgac cctaatacag gagaatcgtt
    30301 gatggaacgt acggtattga ttgctaatac atcaaacatg ccagtagcag ctcgagaagc
    30361 ttctatctat acgggaatca caattgcgga atatttccgt gacatgggtt atgacgttgc
    30421 tatcatggca gactccactt cacgatgggc agaagcactt cgtgagatga gcggacgttt
    30481 ggaagaaatg cctggtgatg aaggttatcc agcttatctt ggttcacggc ttgcggaata
    30541 ctatgaacga tctggaagag tcattgcatt aggatcagaa ggtcgcgaag gaagtataac
    30601 cgcaatcagt gctgtatccc cgtctggagg ggatatttcg gaaccagtca cacaaaatac
    30661 attgcgggtc gtaaaagtat tctggggtct tgattccagt ttagcccaaa aaagacattt
    30721 tccttcgatc gattggatac aaagctattc tctttattca acagaagtag ggaagtatat
    30781 ggatcatatc cttcaagctg actgggcatc catggtcacc gagggcatgc gtattttgca
    30841 ggaagaacag cagctgaatg aaatcgtgcg tttggtaggg attgattccc tttcagataa
    30901 tgaccgtctg acattagaag tggcaaaatc cattcgtgaa gattatttgc agcaaaatgc
    30961 ttttgatgat gtcgatacat tcacttcaag agagaaacaa ttcaaaatgt tgaagatgat
    31021 cttgaccttt ggtgaagaag gacgccgtgc gttgtcgtta ggtgcttatt taagtgagat
    31081 catggacggt accgtatcga ttcgtgaaag gatcggacga agcaaatata tcccggaaac
    31141 agaattagaa aaactagatc aaattattgg tgaaatcaag caaacgatgc aaacgatcgt
    31201 ttcagaagga ggcatgagca atgattaaag aatatcgtac gatcggtgaa gtcgtcggtc
    31261 cattgatggc ggttgaaaaa gttgctggtg tcaaatatga agaattaatc gaagtccgta
    31321 tgcaaaatgg cgagattcgt cgtggacaag tattggaagt ccaagaagat aaagcaatgg
    31381 tccaaatatt cgaaggaaca agtggtatca atttacgtga ctcttctgta cgatttttag
    31441 gccatccttt agaactaggt gtatcggaag acatgatcgg tcgagtattc gatggtttgg
    31501 gacgaccgaa agataacgga ccagagatcc tgcctgaaaa gcatttggat attaacggag
    31561 aagtaatcaa tccagtagct cgggattatc cagatgagtt tatccaaaca ggtatctctg
    31621 caatcgatca tttgaataca ttagttcgtg ggcaaaaatt accagtattt tctggctctg
    31681 gtcttcctca taaagaatta gctgctcaga tcgcgcgaca agcaacggta ctcgattcat
    31741 cagatgattt cgccgtagtc tttgctgcta ttggaatcac ttttgaagaa gctgaatttt
    31801 tcatggaaga ttttcgtcaa acgggcgcaa tcgaccgttc tgtcatgttt atgaatttag
    31861 caaacgaccc tgcaatcgaa cgtatcgcta ctcctcgtat ggctttgact gctgcagaat
    31921 atcttgctta tgaaaaggga atgcatgttt tggttatcat gacagacatg accaactatg
    31981 cagaggcatt gcgagagatt tctgcagcac ggcgagaagt tccaggaaga agaggatatc
    32041 ctgggtatct ttacacgaac ttagctactt tattcgaacg agcaggaaga atccgcggac
    32101 taaaaggatc ggttactcaa attccgattc taacaatgcc agaagacgat aaaactcatc
    32161 caatccctga cttgactggt tatattacag aaggacagat catcttgact agagagcttt
    32221 acaagagtgg gattcagcca ccaattgatg tactcccgtc tctttcgcgg ttaaaagata
    32281 agggaactgg acccggaaag acaagagaag accatgcagc tacgatgaat cagctttttg
    32341 cagcctatgc acaaggaaaa caggcaaaag aattagccgt agttttaggt gaatctgctt
    32401 tatctgatgt agacaagatc tatgcgaagt ttgctgagcg gtttgaaaaa gaatatgtca
    32461 atcaaggatt ctacacgaac cgttcgatta ctgaaacact tgatctaggg tgggaactgc
    32521 tatcgatgtt gccaagaacc gaattaaaac gaatcaaaga cgacatgctg gacaaatatc
    32581 tgccagaagg gaagtgagtt ctgatggcac gattgaatgt gaatccgacc cgcatggaat
    32641 tgactcgatt gaaaaaacag ttgacaactg ccacaagagg gcataaatta ttaaaagata
    32701 agcaagatga actgatgcgt caattcatcc tgttgattcg aaagaacaac cagctgcgtc
    32761 aagaaatgga agagtctatg acagaagcaa tgtctgattt tgtattggca aatgcttcga
    32821 tcacggaacc tttcatcgaa gaattatttg ttttgccggc ggaaaacgtt gatttgtcta
    32881 tcgtagacaa aaatatcatg agtgtaaaag tacctgtgat gaattttgaa tatgatgaac
    32941 agctgacaga cacacctttg gaatacgggt atttgaattc cagtgccgaa ctggatcggt
    33001 caatcgatcg gtttactacc ctgcttccaa aacttttgga actgacagaa atcgaaaaaa
    33061 cttgtcaact gatggcgagt gaaatcgaaa agacacgtcg gcgagtcaat gcattagaat
    33121 atatgacgat ccctcaatta gaagaaacga tctattatat tcgtatgaag ctggaagaaa
    33181 acgagcgcgc agaagtaaca aggttgatca aagtaaaaaa tatgggtacc actgactaag
    33241 tggtatcttt ttttaaaaga ggaaaacgat gattaaacaa agcaaacaaa taaagaaacg
    33301 tttgccggct gttcagcttc tcgcattagg attttttctc ctgattttag ttggcggcgg
    33361 cctacttacc ctaccatttt ttagtaatag tgggcatggg acaaatttta tcgatgcgct
    33421 tttcactgca acttctgctg tctgtgtaac gggattgaca acattgaata cagcagagca
    33481 ttggaacagt gctggtcaat ttttgatcat gcttttgatt gagatcggcg gtcttggttt
    33541 tatgatggtt ccgattctat gctttgcatt gataaagaag aaagtcagtc tcagcacacg
    33601 tattatatta aaagaagcgc tgaatctaga agaagtatca ggtgtgatga agctcatgct
    33661 ttacatccta aaattggcct ttgtgatcca attgattggt acggttgctt tatcttttgt
    33721 atttgtgcct gaatttggct ggttgaaagg tatctggtac agtttgttcc atgcaatctc
    33781 tagtttttgt aatgcagggt ttgatttgtt aggagacagt ttagccaatc accagcaaaa
    33841 tgtttatttg atcatggtgg tatctgcttt gatcatttct ggtgggttag gcttcatcgt
    33901 atggcgtgat ttactggaat atcatcagaa aaagaagatg acgattcatt caaaaatcgc
    33961 attaaccgtt acaggtaccc ttttattagg cggattcgtt gtgttctttt tcacagagcg
    34021 caatggggca acgctagtgg aagggaatat gtttcaacga ttggcaaaca ccttttttat
    34081 gagtgtgaca cctagaacgg ctggatatta ttcagttgat tacctccata tgagccatgc
    34141 aggtctgatt ttaacgatgt ttttgatgta catcggcgga acatctgggt cgacggccgg
    34201 cggattgaaa acaactacgt taggtgtgtt gctgatccag atgcgttcga tgttgaaagg
    34261 acgtacgaga gcggaagcat ttggccgtac catccgacaa ggcgcagtgt tgcgggcact
    34321 tactttattt tttgttacgt tgacgttgtg tgtagtcgcc atcatgattt tatcggtgac
    34381 tgaaacgata cctaaaactt ctggcatcga atatattgct tttgaggtct tctctgcgtt
    34441 tggtacagta ggtcttacga tgggattgac gccagacttg actgcaatag ggaaattgat
    34501 cattatagcg cttatgtaca ttggacgagt tggtgtattg actgtggtct tctctctgat
    34561 gacaaaagca caaagaacac aatcaaaata caaatatcca gaagaaagtg tcatgattgg
    34621 ataatttcat cttctgacag aaacctagtg atttagtaaa ataagaaaat aaaataattt
    34681 ttcttgcttc ttggatactt taagtgcaaa atgttcgttt attttttgag gcactacccg
    34741 ttgttgaacc tcgggtagtg cctctttttt attgaaagga atcaataaga tttgattcct
    34801 ttatttatca ataggttata attcatattt ttttattttt tcttttacga tacttagtcc
    34861 agaagctaaa atttcaaggt tattagagga tagggaaatt cgaacgaatg catctggttg
    34921 cgcacgtgta gtaaagcgtc tggaatgata aagtcggata ccgttagcaa gaaagtcatt
    34981 ctcaattatc ttagggtcaa tctcaggatc aactggaaga attcgatagt aagggacacg
    35041 attcgttggt ttttctactt tgaaaagaga atcaaaaagc tgattggctc tttttgtaag
    35101 acttaattta gtttctaaga tcctatttgc ttcatttgaa tggaggattt gagtgatgac
    35161 ttccacatct aatccagaag ttttcacatt tatattaaaa attgcttgtt ctatcttgct
    35221 ttggacatgt actggaacta caagataagc aactcgcaat ccagaacaaa taaattttgt
    35281 cattccagct aagtagattg tttggttagg taataaattt tggaaaggag gaatgatcgt
    35341 atgttgatag taagttgtta aaaatgaatg gatatcatct tcaataaccc atagaccttc
    35401 tttttcaatc acttcggcta attgctctcg tcttttgtga gagatttgaa accctatagg
    35461 attattacaa gaaggcataa gaaagacacc atgaatcttc ttttttctac attcctgaat
    35521 caatatatca ggtcgcattc cttgctcgtc aaaatcaatt ggaacgatct ctaaatgata
    35581 taactgagcc aattcaatga aattagcgta tgtatatcgg tctgttgcta ttctatcacc
    35641 tggagagaaa agtgcagaaa gtgtgatagc caatccattt tgaacaccgg aaacaataga
    35701 tagagattct aaggacggaa tgactccttg agtttttaac caatttgctg cagtagtcaa
    35761 ttgaaaattt gtgcctttgg gatcttggta attaagcaaa ccaacaagat ttgggttatt
    35821 actagttgat tgaataaacg ggacaacgaa tttattacat tcttcaaaag aactaaccag
    35881 accaaaatca atgatatgtt cggttacttc attggtagag atggtgatgg actcaaagac
    35941 attgggagaa ataaatgtgc cacttccaat attcgtatac agcaaacctt tctcaattcc
    36001 atatttataa gccttgccaa cggtagtaaa atttaaatct aaataatcag ctagctctct
    36061 ttgggagggt aactgagtgt ttttctgtaa tttattcttt aaaatatctt gttctaattg
    36121 ttgaatcaac gatcgataat aaggacgctt caatttttgt ttgtctggtc gccaagttaa
    36181 cgggtaattg tcataagaat taataggcat tttctccact ccttaaaatt gtataccata
    36241 caattttacc attgattgta ttgattttag aagttaatct tttgtgagga gggaattgtc
    36301 tatgaaaatt attaattttg aggaagtagt agcttctttt agttttgaag aagcgattca
    36361 agtaatgaaa aaatgttttt ttgattatga aagtggtaaa atcagccaaa atcctcgatt
    36421 ggtggaaatt ttacctgacg gaaaaggcaa aaatatgttt gcgatgatgc ctgcttattt
    36481 gggggagaac agatattttg gcacaaaagt cattaccgct tttccggata atcatcagta
    36541 tcatttacct tctcatttag gagagatttt cttgtttgat gctcaaaacg gactacccaa
    36601 agcattgata aacgcaaatg cagtcacctg gattcgaaca gctgctgtat ctgcgctggc
    36661 aacagattac ttagcaaatc cgcatgcaga aacacttgct ttaattggag ctggtcaaca
    36721 agcattgtcg catttgactg cgatttctac cattcgtccc atcactacag tgtttgttta
    36781 cgatatttta gaagaaagac gaaatacttt tatcgctaaa gctaaaaaac agtatcctaa
    36841 aataacgttt ataaatgcaa tatcagtaga agatgcagta cgtccagcgg aaatcatttg
    36901 tacgttgacc tctagtaaag aggcatttct tcaaaaagag tgggtaaggg aagacgcaca
    36961 tatcaatgct gtgggcacat ttactcctga tacaagagag ataagtacat cgttgatgga
    37021 aacttctcaa atctatgtag atgattactc agctgcctta acagaaagcg gggacctgct
    37081 tatagccatg gcagaaggag atttagagga atcttgtatt gttggtacat taggcgaatt
    37141 agtttctgag aaaaaaacat tttataaagg agaatcgagg ccgacgattt tcgacgcagt
    37201 tggtctagct attgaagatc tttgttgtgc agaatatatt tataacaaat tagagaaagg
    37261 ggctttaaaa tgaacttaga ttattacgta gttgatgcat ttgcagatga ggtgttcaaa
    37321 ggaaatccag cagcggttta tgtgctagaa gaatggctgc cagaaggtac gatgcaaaaa
    37381 attgccattg aaaacaattt atctgaaaca gcatttacag tgaagaaaaa ccaagaattt
    37441 gagcttagat ggtttacgcc agatcgagaa atcgatcttt gtggtcacgc gacattagca
    37501 acagcatttg ttttatttaa ctattacaaa atacctgatg aaacgattaa attttctact
    37561 caaagcggta atctatttgt gacaagaatt aaagattatt attacatgga ttttcctagt
    37621 attatgccga aaaaagtgcc gatattgtct gaatatgaag aagcgattgg ggctaagatt
    37681 aaagaagcct acttagcacg tgatttattt ttcgtattag aagatgaaaa aacggtggct
    37741 aaattgcagc cagattttac agctatcaaa aattttgaat taggaatagg agtcatcgtg
    37801 acagcagaaa gtgtgcaaaa agactttgtt tctagaacct tctttccaaa attaacaatc
    37861 aatgaagatc cagtatgtgg atcagcacat tctaatctta ttccttattg ggcagaaaga
    37921 atgaataaaa caaaattgtc agcttatcaa atgtcatcaa ggggcgggga tctagaatgt
    37981 gaattaaaag aagatcgtgt gataatagga ggaaaagcag ttttgttttc taaaggtacc
    38041 tcgtttattt gatttctttc aaatgaatta aaaataaatt ggtggagagt ggcaacctta
    38101 tagctacaat ggttgttaaa aaaagacgca aactttttca atttaatgaa aagtttgcgt
    38161 ctcattttaa ttattggtgt ttgtttttta ttcaatcaag agtaaaatgc cccatactaa
    38221 ctatcctcgg atgacttcga ttttataacc atcagggtca atgacaaagt agtaagaagg
    38281 cgcagtgcca ggtaatcctt ttaagtcagt aatctcaaga ccagcagctt tatgttgctc
    38341 gtgtaatttt tctagatcat cagctgctat agcgatatga ccatagccgt ctcctagatc
    38401 atacgcacca tgatcatagt tgtaagtcaa ctctaattca tagtcatccc caggaagtgt
    38461 caaataaaca agtgtaaatt tgttttctgg aaaatcacgg cggcggcttt cttcaaaacc
    38521 aaatgccttt tgataaaatt cgattgatgc ttcaagatct ttcactcgaa cacatgtgtg
    38581 agccattttc atagattcat ctctcctttt ccttttactc aatcataaca aaaagaagta
    38641 aggaaatagt tgatttgtgc ttgttcatga gaaatttctc atgtaaaatg gatagaaaat
    38701 aaaactgtta aggtggaaac tattcatgga taaaccaatt tttggtgaaa aaaagcaatt
    38761 tgctgattat caaacccgtt atgcagcata tattgtcata gaaagagatc agcagattgc
    38821 agtaatcgag gctccaaatg gtgctttttt tcttcctggc ggggaaattg aaggagaaga
    38881 gacgaaagaa gaagcgattg tccgtgagct gatagaagaa atgggaattg tggcagaaat
    38941 ttcttcttat ctgggagaag ctgatgagta tttttactcg aattatcgtg caacttatta
    39001 ttataatcca ggatatttct ttgttgctga ttcttggaag cgtataggag aaccaactga
    39061 aaagaccaat aaaatttggt gggtgagccc tcaagaagcg cttgtgaaat tgaaacgtgg
    39121 tagccaccga tgggcagtcg agagatggat cgaaaaaaat aaaaactgaa agaaagcgag
    39181 tagatcagct ttctctcagt ttttttattt attacagtac atattttttg attgcttcag
    39241 ctacaccgtg ctcgtcgttt gatgaagtga tgacatttgc tgcttctttg acaagagaaa
    39301 cggcatttcc cattgctact cctagaccag catattcaat catggataag tcgttctcgt
    39361 tatctccgat agccatgatt tcatcttgat caataccaag gtgctgtgcg agattcgcaa
    39421 ctgccgcacc tttacttgct tctttattta gtacttcgaa gtaatagggc gcacttttga
    39481 ccgttgtgta tttatcacgg aaagtttgcg gtaaacgcgc aattgctgca tctaaaattt
    39541 ctggttcgtc gatcatcatc attttgacga tgttcatgtc tggtgtcatt tcttcaggtg
    39601 ttcgatattt tagcggcatc ttgactaaac ttgcttcgtg gatcgtataa gcgctgatat
    39661 ctcgattagg cgtgtagatc gctttgtcat cgatcgaatg gagatgactg ccgacacggc
    39721 gtgccattac ttcgatctct aggaaatctt catgtgtcag tccgtgacgg gcgatgattt
    39781 tacctgattt cgtttgttgt acgagtgccc cgttataagt aataacgtaa tcattatctt
    39841 gaaaaaggtt caactcgttt aactgttcct ggacacctgg taagggacgg ccagtgcata
    39901 aaacgatcga aacacctttt gcaacagcag cggcaatcgc ttcttttact tcttttgtta
    39961 cttctctttt ctcatttaat aaagtaccat cgatgtcgat agcgactagt ttgatagaca
    40021 taatttcctc caatatattt taatttattt caatcaatgc gccattacgg atatggctgg
    40081 caaattcttg ataagtttcg tcaaataaat cataatgatc acgcaaggac ggatcaacca
    40141 tttcttttgg aaagaaaaat cgctcatctc cttgttcttg tcccgctaat gcagcaacaa
    40201 gctgactaac ctgtgataat tctatcaaag ttccgtcatt tcgcaaaatc tcgatttgtg
    40261 tgcgatgtct gccttgttct gggcgataaa aatcataagg tagatcgtag ctagaattca
    40321 cagcagtgta ataaacagga ttatatccga ccttttctac taacaaagtg agttcttgga
    40381 ctaattttga atcccggttg ccagaaaaag tagcagattt cagtggttta cgattcaaaa
    40441 aacgtttagc taaatcattt aaaataggat cagcagattc agaccattga gtaaagtaag
    40501 tgcccaagac cccatcatca agtttgaggt attcttctaa agtaaagctt ccgtcaagaa
    40561 atggcagaag taattgagaa tggagttcaa aactgctggc atcttcttga tacaactcgt
    40621 gtgcgcgatg aagcagatgc tccaaaatta cttccatacc acgggaaaca ggatggaagt
    40681 acacttgcac atacatttga tatcggctaa cgatataatc ttccactgca tgcatgccac
    40741 tcatggaaaa agcgatcccg ccttcataag gacgaatcac acgtaatatt cgggtaagat
    40801 caaatgttcc atattctgtt ccagtgaaat aagcatcccg aagcaaatag tccattcgat
    40861 ctgcatcgat ctgactagaa atcatttgga caacttgtgg gttggggtaa gttttttgga
    40921 tcacactagc taccttttca ggaaaacctt cttctactcg gttaagaatc tgatacactt
    40981 ctgtttctgg agaagtgatg atctctacag tgatggcttc atgattcgta tggaagatat
    41041 gttcaaatgt atgagagtaa ggaccatgac cgacatcatg caacagtgcc gcacataaag
    41101 tcaccagccg ttcctgatca tcccagcctc cgttgcctat tttttctttt gaaaaatttc
    41161 gagaaaagat atcgcagatt cgtcttgaaa tctcataaac gcctaatgaa tgagtaaaac
    41221 ggctgtgttc tgctccgtga aaagtgaaag aagaagtgcc taattgttta atgcgtcgta
    41281 gacgttggac ttctttcgaa ttgatcaaat ctaagattac ttgatgctgg acatggatat
    41341 agttatggac tggatcacga aaaacttttt ccataggcag catttgatat ttataagggg
    41401 ttgtcataat gtagctcctt tatgttatta cgttgttcca ttctctggat ttggttgttc
    41461 cattgctcca gctggatttc tttttttagc cagtcggtag aatcctgtaa atcacttgca
    41521 gaatacagct tttcaaaagc ttttgcaaat gcttctttga cttcttttac aaaaaggggt
    41581 tggtcaagca gttcttcaag tgttgccatt gtagcaggat ccactgcagg atagccattt
    41641 gtaccaaagt cttcttttaa agcagattga taaaatcgct tcatgacttg cccacgtttt
    41701 tcctgattac cgttgacact taagtacatc ataacagaaa tcccattttt gatccgacgc
    41761 tgagcgatac cggcaaattt tttgccatgg atgcttaaat cataagttcc aggacaataa
    41821 gaatgggtga tttcgaatgc ttgtatcggt gcctttggaa aagcgtattt agtcaatagg
    41881 agcatttgct cgtaagcgtc atctatggtt attttttttg tgtcactttg ggggaaaatc
    41941 aaagaaatat tcaaaattcc ttcatctgat acgatcccta atccacctga atttctgatc
    42001 actggagcgt aacctgcatc ttccagtgtt tggatcccgt cacttagaaa aggagttcga
    42061 acatccttca tacctaagat gactgtgcag tcatattgcc agaaatgtaa aaagatttgc
    42121 tggtgttctt tagaatattc cgttaatata tctgttaatg caaaagggga aaagtcgttt
    42181 ttttgataaa tgtgctgatc tagtcgaatc gcagggttca ttcaaccggc tcctttgtat
    42241 aaattcatat tttctacaat attatactct aaaatcaaag agttgttttg gaaaaaaggt
    42301 tttctgtaaa aatggacaag ttggttgaca aaacaaaaga aactaggaac aatgtagcta
    42361 tgagaagtaa aggagaatga ataatggaat tatcacaagg aacaccgatt tcaatcaaat
    42421 tgcgtacaaa agtaaaacag caaggggaag tgcaagattt ttattttgat ttgaaagggc
    42481 aaatggtgac aattggcgat acgctgtaca tacgttataa agagattcag gaggagacgg
    42541 gcgatgagat tcctgtaacg atcaaattag ttccagatgg tcatgtacag ctgatccgtg
    42601 caggagaaat gcggatgcgt ttgaaatttg gctataaaga acggttagaa acatcctatc
    42661 gaacaccata cggtatgatc cagattgcta cttttacgaa agaactgcat gttagtttga
    42721 aagaccgtcc cacagcaggg aaggttcgaa tcgattatga tctgttcatg ggaccggaaa
    42781 aaatcggcga atattatttg accttggatt ttacagcgta aatataaaag aaaagtttga
    42841 ttttttgtgt ctgattttgt atgataagga gtagactgtg aaaggacgtg tcctgattgg
    42901 aaattagtgt atttgaaggt gcaaacaaaa gcgaattatc aatgatcgaa gtagcacacg
    42961 cgatcttaga acaacgtggc gatgtcatgg atttttctga tttagctaac cagatccaaa
    43021 actatcttgg gaaatcagac agtgaaattc gtgattcact cgcacaattt tatactgact
    43081 tgaatattga cggcagcttt atctcattag gggataatcg ttggggcttg cgttcatggt
    43141 atgctatcga ttcgatcgat gaagaagtaa accatggaat ggacgaagag gatgaagata
    43201 ctccacgtcg ccgtaaacgc aagaaagtca acgcctttat caatgatgat gaagacgcga
    43261 tcgattacaa tgacgatgac ccagaagata cagatctgac agaagaagat gacgatgatc
    43321 tgtttgatga cgatgatgat gaagatgaag aaatcgctgc ttataattct gacttgcaag
    43381 aaatcggagc agatgacccg acagatgatg aagaagactt gccaggaaat atcgaagaag
    43441 atttaagtat catagacgaa gacgatgatg atgaagatta tgaagaggaa gaattttctg
    43501 actctgaaaa agaataaaca ttattttctt acgagaggtt gtgacagaga cgatcagcct
    43561 atcagaataa ggaggtgtga cacgattttt gtcacacctt cttttttgta tataaaaatc
    43621 ccaagtaaat acataaaaaa taaaaaaatt gaaactttta gcgcaccttg tacgtcatat
    43681 taagtgaggc agaaaggagt ggagaatgat ttttactgga tataagaaaa aacggcagat
    43741 cgaaaaatac cgtcacctgc tgaatggact catcgaaact gattatcaaa aaatgttccg
    43801 tatcacgatg aattacgtac atgataaaga agaggcctta gatgtgatgc aagatagttt
    43861 tcataaagcc ctgaactatt ttgaaaaaga aaaagagatc gagcatttta gtgcatggtt
    43921 ttatcggata ttgatccgca cggcattaga tagttggcgc agacaaaaaa ggacgcctgt
    43981 ggacttattt gaaattcaag atatccccca acagttacct ttagaaactt ccgttgcaga
    44041 gctccatatg attttagata aaatagacag tccggaaaaa gagattctga tcctctactt
    44101 ttttgaagga tttcgtttga aagaaattgc gactatcttg gatatgaatg aaaacacagt
    44161 taaaacgaaa atgtaccgct cattgaatgc tttacgtcaa atcctagaat gaaggagaga
    44221 agagtgccat gtattcccaa aaagaaaatt taaaaaaact aaagaaaact tataaagaac
    44281 aagcaattcc caaagggctt aaagaggaga tccgccagcg ttttattatc gaagagcaat
    44341 catttataaa agcaaagcgg agaaagagac gtctccaagg gttcggagta tctttggcta
    44401 tcgtaatgat tacaacaagt agccttcttt ttaatagtca agttcgaagc tttgcagaag
    44461 atttacccat cttaggatca gtcattgaat tgatcttagg cgaacgcttt actgatcgat
    44521 ctgaaaaaat cgatattcag gtaccgaaga tcaatacaca aaatgagaaa gaaaataaaa
    44581 caattcatgg attaaatcaa aaatactttc gcgaaggaca agcagatttt gaaaaagctg
    44641 aaaaagaata tggaaatttt gaaacggatc attaccaagt tttgggagat tatcagaaaa
    44701 tcgtagacga taaccggttt ctcgtgattg aaaggcagat cacccaaaca gcagcagata
    44761 gccatgttga aaaaagatac gacacaatcg acaagaaaaa cagtgtccag ctctcacttc
    44821 cacttttatt caaagatgac acctatctat ctgttttgac aaaagaagtc aaacggcaga
    44881 tggccgaaca agtcaaggaa gatccatcta agtactattg gactgagcaa gatattcaag
    44941 aagggacgat agaaaaacca acacttgtta cgcctacacg aagtttttat ttgaacaaag
    45001 agcatcaatt agttttgact ttttctcaat acgaaattgc tcctggttat atgggtacac
    45061 cagaatttgt cattcctaag tccgtgacaa aaacgatttt ggcatcggaa gattatttgg
    45121 atcattagac gagaagtagt tgcgactagc agtttcaatt ttcaagtaag tacaagtaaa
    45181 taataagaag agaaaaagag aaagaagaga tatagtgaaa agaaattatt tagttatcag
    45241 tattattgct ttatccgtgc ttttgttttt cgaaattact tcggtggcct ccttgatcac
    45301 cgaagtaaaa ggacaaacac actcttcgga gcattcgtca caatctttca aacaatcaga
    45361 acaatcaacc attaaaagcc aatcaactga aacagctaac gtcaaagaag ccattcaaga
    45421 atcagcggaa aaggtacaaa gtcagtcatc acaatcaaca caagacagta caaaaacgag
    45481 ccgagatccg gctgtcaaaa gcgtcgcaat cagctttgat gatggaccag gagcgaccac
    45541 aacaccgcag cttctgcgaa tcttaaaaga aaaaaacgtg catgccactt ttttcgtctt
    45601 aggagaaaat acggcgcagc atcctgaaat cgtgaagcag acagctgaag cagggcacga
    45661 gattggcaat cacacatacg atcatcagaa tctggccact ctttctgccc agtcgatgac
    45721 ggaggaagtg acgaaagcag acactgagat caaaaaagtc actggcaaaa cccccacttt
    45781 tgttcgtccg ccctatggtt ctgtcacgaa tgtaggagca acgatcatcc agcgaccgat
    45841 catcgaatgg tctgttgatt cagaagattg gaagacaaga aatcctgatt tgattttgca
    45901 gaagatccaa gcaacagtat acgatggggc aattatttta ttccatgata tctatcctga
    45961 aacgattcgt gccgttcctc aagtgatcga ttatctgaaa gagcaagggt atcgcatcac
    46021 gacagttggg gatttattag ggcatccaac ggctgtcgag aactattatg gcagaaacga
    46081 tcatcggcca gttcagtaag tgagacaagt atctttaata aataacacat tttaataagt
    46141 agttgaacac ataactacct tacttgcaaa ggcttaacaa tatctataca ggtacaacaa
    46201 aaaactgtcc accaattttc tttggcggac agttttcact taaaaataaa gaagcaacta
    46261 ttcgtaaatt atgctaaaat agcagtagaa cgcgtcctga gggaatcgaa cccccgtctc
    46321 aagaaccgga atcttacgtg atatccacta cactaaggac gcaagcactg ggataattgt
    46381 aactaaacag ataaaaaatt acaaggggat tggacaaaaa aatgaaattt gagcaaaatt
    46441 tttcacaaaa acagcagcag acacagaaac tagccatgac gcaacagttg caacagtcca
    46501 tccaagtttt acaatataac agtgaggagc tgttggcatt cgttgagaat caagcaatgg
    46561 aaaatccatt ggtggaagtt gttgagccgg aatggcagcc agattacata aaagcttctt
    46621 catcttctta tgaaggagaa gagacaaatt acctaaatca gattcctgat acaaaagggt
    46681 ctttatttga ttcattgatc gaacaagtcc atttgaatta ccgagatact tttttgagga
    46741 aaatcgttct ttatcttgta gaatacatcg atttgaacgg atttttgacg attagtttag
    46801 aagaagccgg aaaagagatt ggagctacgc ctatccaaat gctcgatgcg ttgactctga
    46861 ttcagcaatt agaaccagct ggagtaggtg cacgtagttt gcaagaatgt ctcatgcttc
    46921 aaacagaacg agatgattat gcgccggaat tagcttatat cgtgttggaa gaatgttttg
    46981 aggaactggt ggagcgaaaa tggaaagaaa tcgcacaacg tttttctgtt gatctacatg
    47041 ctgttcagca gatattcgac tatttacaaa cgttgagtcc aagccctggc cggattttcg
    47101 accgtagcag cgaattgtac attattcctg atgtccgggt attagtggac gacgataaaa
    47161 atgtacaagt tatctcaaac cgaaaaaatc agccaaatat acgctttcaa gagagttact
    47221 tcaaacaaat gtcacaacaa gcagataaag aaactgaaaa ttatttaaaa gaacggaaac
    47281 aggaattcga atggttgaag aaaacgatcc tacaacgtgg ggatacaatt ttgcgggttg
    47341 ctcaagtcat tgtttcccgg caaaaagctt tctttatcga caaggaacgt ccaatcaagc
    47401 ctcttacgtt aaaggaagtt gcaactgaga tagatgtgca tgaatccacg gtcagtcgtg
    47461 cagtcaacgg gaaatatttg gaaacagact tcggtgtatt tgaattaaaa aaatttttca
    47521 ctacacgaat tcctacgaat agtacagaac agacagaaga cctttcagca gatacagcga
    47581 agaaaaagct gcaggaatta gtcgatcaag aagacaaaaa caagccgttg tctgaccaga
    47641 aattggttga attgctgaaa aaagatgaga tagcgatctc aagacgaaca gtagcaaaat
    47701 atcgtgattt attaggaatc ccgagttcat caaaaagaaa acgttatgat aactaatcag
    47761 tcaaaagact agaaaaagta tttcactttt tctagtcttt ttagttgaaa aacgagagca
    47821 aaactgttag acttacagtc gtgaggttga gatttccctt tattgatgtg aaattcgaat
    47881 agttaatttc tttttttatc gtatatgggt cgttttaagt ctacattgga cgtaaagtgt
    47941 ccaactaagg agatcgctat gctggatgaa ataaaaatga ttgaatctgt tgcaccagat
    48001 attatcgaag tgttgcaaga acgctataaa attttacgaa atatctattg gatgcagccg
    48061 attggacgtc gaagtttatc ggaaagtatg gggatcacag aacgagtatt gcgaacagaa
    48121 acagatcttt tgaaaaatct gaatttgatc gacacctcaa aaagcggtat gacgctgaca
    48181 actaagggcg aagaagttta tcaaagcctt gaaaacttca tggatcagct tttaggtacg
    48241 catcaaaccg aacaacagtt ggcagaatat tttggtaacc aacgctgtat cgttgtttca
    48301 ggaaacagcg aagagcagac caaagtggct gatgcattcg gcgaagcgct gagcgaagcc
    48361 ctagaccgac tacttccaga aggcgagaat atcatcgctg tgatgggagg aactactatg
    48421 gctgtggtag ccgaacaatt gtctaatctg gaaaataaga aacggcataa cctgtttgtc
    48481 cctgcaagag gcgggattgg tgaagcgata actgtacagg caaattctgt cagtgcaaga
    48541 atggctgcta aagcaaacgg taaccaccgt gcactttatg ttccggaaca attaagtctg
    48601 gcaacttaca attctttact caatgagcca tctatccaag aagtcttaaa cttgattagt
    48661 gaagcgaatt gtgttattca tagtattggg cgtgcattac acatggcagc acgtcgtaag
    48721 atgactgaaa aagaattagt catgctgaaa caagcaaatg ctgttgcgga atcttttggc
    48781 tactttttca atgaaaaagg tgaagtcgtt tataaggtcc ctagaatcgg catagaattg
    48841 caagatttgg aaaaagtccc gatcatcatg gcaatcgcgg gcggaaaatc aaaagctaaa
    48901 gcaattcgag cttatatgaa aaatgcacca aaacaaacgt ggctcatcac tgatgaagct
    48961 gctgcaaatg agattttaaa aggggtaacc ctttaaaata aatatttttt tgattttcat
    49021 aaggaggaaa tcttaaatga cagttaaagt aggtattaat ggttttggac gtattggacg
    49081 tctagcattc cgtcgtatcc aagatgtaga tggaatcgaa gtagtagcaa tcaacgactt
    49141 gacagatgct aaaatgttgg cacacttgtt aaaatacgac acaactcaag gacgtttcaa
    49201 cggaacagtt gaagttcatg aaggttcatt caacgtaaac ggaaaagaag ttaaagtatt
    49261 agctaaccgc aacccagaag aattaccatg gggcgaacta ggcgtagata tcgttctaga
    49321 atgtactggt ttcttcactt ctaaatcagc agctgaaaaa catttaacag ctggtgctaa
    49381 acgcgttgtt atctctgctc ctggcggaaa cgatgttcca acaatcgttt ataacacaaa
    49441 ccacgaaaca ttaactggta aagaaacagt tatctcaggt gcttcatgta ctactaactg
    49501 tttagctcct atggctaaaa cattgaacga caaatttggt gttgttgaag gattaatgac
    49561 aactatccac gcttacacag gtgaccaaat gactctagac ggacctcatc ctaaaggtga
    49621 cttccgccgt gcacgcgctg ctgctgcaaa catcgttcct aactcaacag gtgctgctaa
    49681 agctatcggt ttagtaattc ctgaattgaa cggtaaatta gacggagctg ctcaacgtgt
    49741 tcctgtacca acaggttcat taacagaatt agtaacagtt cttgaaaaag aagtaactgt
    49801 tgacgaaatc aatgcagcaa tgaaagaagc ttcaaacgaa tcttacggat acaacacaga
    49861 cgaaatcgtt tcttcagata tcgttggtat gacttacggt tcattatttg atgctacaca
    49921 aactaaagta atgacagttg gcgacaaaca attagttaaa actgttgctt ggtacgacaa
    49981 cgaaatgtca tacactgcac aattagtacg tactttagaa tacttcgcta acttataaga
    50041 tagacaaacg tacaagtgta aattatagac atgtacattt aaaagcgggg aagcaatcgc
    50101 gcttcttccg ctttttttga taataagttt attcaggagg aaataaaatg gctaagaaaa
    50161 cagtgaaaga tatcgattta aaagacaaaa aagttcttgt ccgtgttgac ttcaacgttc
    50221 ctttgaaaga cggcgtgatc actgacgaca ctcgtatcaa agcagcattg ccaacaatca
    50281 actacgttct agaacaaggc ggaaaagcaa tccttttctc tcaccttgga cgtgtaaaaa
    50341 cagaagaaga taaagaagga aaatctttag ctccagttgc aaaacgtcta ggcgaattat
    50401 taggtaaaga agtaacattc gtacctgaaa ctcgcggaga acaattagaa gaagcaatcc
    50461 gcaacatgaa tgacggcgac gttgtcgtat tcgaaaatac acgatttgaa gatattgacg
    50521 gtaaaaaaga aagcaaaaat gatacagaac taggtaaata ctgggcttca ttaggcgatg
    50581 tatttgttaa cgatgctttc ggtacagctc accgtgcaca tgcttctaac gtaggtatcg
    50641 cttcaactgg tatcccaaca gttgctggat tcttgatgga aaaagaaatc aagttcatcg
    50701 gtgaagcagt agaagaacca aaacgaccaa tgattgcaat ccttggtggc gcaaaagttt
    50761 ctgataaaat cggcgtaatc gaaaacttga ttcctaaagc agataaaatc ttgatcggtg
    50821 gcggaatgac ttacacattc tacgaagcaa aaggaatcaa gatcggtaac tctctagtag
    50881 aagctgataa agtggaacta gcaaaagaat taatcgaaaa agcaggcgac aaacttgtct
    50941 tgccaatcga caatgtctgt gcaccagaat tttcaaatga tgttgaaaca caagtaatcg
    51001 aaggagacat tcctgatggt ttgatggctt tagacatcgg cccagcatca gtaaaattat
    51061 ttgctgatac attacaaggt gcaaaaacag ttgtttggaa cggacctatg ggtgtatttg
    51121 aaatgagtaa ctttgctaaa ggtacaatcg gtgtttgtga agcaatcgct aacttagaag
    51181 gcgcaacaac aatcatcggt ggcggagact cagctgcagc agcagaacaa ttaggatttg
    51241 ctgacaaatt cacacacatc tcaacaggtg gtggcgcaag cttggaattg cttgaaggta
    51301 aagaattacc aggactagca gcaatcaacg ataaataaac gaccaagttt gctcaattct
    51361 gacgagtaat cgatcaaaag gtgaagggag ttttcatgac tccctagcca tttttcaata
    51421 aattaaggag tgtgttcctc aatgcgtaaa cctattatcg caggtaactg gaaaatgaac
    51481 aaaactgcat cagaagcaaa agaatttgct gaagcagtaa aaaacaaaat cccttcaaat
    51541 gacaaagttg attcagtcat cggatctcct gcattattct tacaagaatt aatgacatca
    51601 gctgaaggta cagaactaaa aatctcagca caaaactgct actgggaaaa ctcaggtgcg
    51661 ttcactggtg aaacttcacc agcagctctt gctgatctag gtgttcatta tgtgatcatc
    51721 ggacattcag aacgtcgtga atatttccat gaaacagacg aagacatcaa taaaaaagca
    51781 aaagctatct ttgcaaatgg tatgacacca atcctatgct gcggcgaatc tttagaaacc
    51841 tatgaaacag gcaaaactgc tgaatggatc gaaggacaaa ttacagctgg tttagctgat
    51901 ctttcagctg aacaagtgtc aaacatggtt attgcttatg aaccaatctg ggcaatcggt
    51961 actggtaaat cagctgacgc acaaatcgct gacgaaattt gtggagttgt acgtcaaaca
    52021 gttgaaaaac tttatggaaa agaagtatca gaagcagttc gtatccaata cggcggttct
    52081 gtaaaaccag aaaatattgc tgaatacatg gcaaaagaaa atgttgacgg tgctttagtc
    52141 ggtggcgcaa gcttgcaagc agattcattt ttgtcattgt tagacgctgt aaaataattg
    52201 ttgaaaattt gcgaaaaatg caagaaatgt ttgcactaat gagcaaaatt aactaaaatc
    52261 gtatatgagg gaaatccctt aggaaaaaac aaactcaaag gagagacaaa acatgtcaat
    52321 tattactgat gtttacgctc gcgagatctt agactcacgt ggtaacccaa caatcgaagt
    52381 agaagtatac acagaaagcg gagcttttgg ccgcggaatg gttccttcag gtgcttcaac
    52441 tggtgaatac gaagcagttg aattacgtga cggagacaaa gctcgttatg gcggtaaagg
    52501 tgtaactaaa gctgtcgaca acgtaaacaa catcattgct gaagcaatca ttggctacga
    52561 tgttcgtgac caaatggcta tcgacaaagc tatgatcgct ttagacggaa ctcctaacaa
    52621 aggtaaatta ggtgcgaacg ctattttagg tgtttctatc gctgttgcac gtgcagctgc
    52681 tgactaccta gaagtacctt tataccacta cctaggcgga ttcaacacaa aagtattgcc
    52741 aacaccaatg atgaacatca tcaacggcgg atcacatgct gataactcaa tcgacttcca
    52801 agaattcatg atcatgcctg ttggcgctcc aacattcaaa gaagctctac gtatgggtgc
    52861 tgaagtattc cacgcattag cttcaatctt gaaagctcgc ggattagcaa cttctgttgg
    52921 tgacgaaggt ggatttgctc caaaccttgg ttcaaacgaa gaaggttttg aagtaatcat
    52981 cgaagcaatc gaaaaagctg gctatgtacc tggtaaagac gttgttcttg ctatggatgc
    53041 tgcttcttca gaattctacg acaaagaaaa aggtgtttac gtactagctg actcaggcga
    53101 aggcgaaaaa acaactgacg aaatgatcaa attctacgaa gaattagttt ctaaatatcc
    53161 aatcatctca atcgaagatg gattagacga aaacgactgg gacggattca agaaattaac
    53221 tgacgtatta ggcgacaaag ttcaattagt tggtgacgac ttgttcgtaa caaacactca
    53281 aaaattatct gaaggtatcg aaaaaggaat tgctaactca atccttatca aagtgaacca
    53341 aatcggtaca ttaacagaaa ctttcgaagc tatcgaaatg gctaaagaag ctggctacac
    53401 agcagttgta tctcaccgtt ctggtgaaac agaagattca acaatctctg atatcgctgt
    53461 tgcaacaaat gctggccaaa tcaaaactgg ttctctatca cgtactgacc gtattgctaa
    53521 atacaaccaa ttactacgta tcgaagacca acttggtgaa gttgcagaat acaaaggttt
    53581 gaaatctttc tacaacttaa aaaacaaata attcttttct aatgaagata catgatcgac
    53641 tattgaaaga tagtcgagta tgatcactta gttaagtaat cgaactctct acttgctgaa
    53701 atatcagcag gtagaga
//
LOCUS       DAFEKH010000016        53371 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.017, whole genome shotgun sequence.
ACCESSION   DAFEKH010000016
VERSION     DAFEKH010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 53371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53371
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.017"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(438..601)
                     /locus_tag="LP386_001028"
                     /pseudo
     CDS             complement(438..601)
                     /locus_tag="LP386_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390190.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
     gene            complement(954..1643)
                     /locus_tag="LP386_001029"
     CDS             complement(954..1643)
                     /locus_tag="LP386_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBL1918280.1"
                     /translation="MESEDLLSRISEVHPNQVWLDKEKVEKRYIYLFFKRMIDIVGSI
                     IGLILASPLMFYVAYRIRKEEPGSPIFFSHTRVGKNGKTFKMHKFRSMCLDAEEKLEE
                     LLDQNEIEGAMFKMKEDPRVTKIGKIIRAKSIDELPQLWNVLKGDMSLIGPRPPLERE
                     VAEYTRYDLQRLYVKPGCSGLWQVSDRNNVSFHKMVELDLEYIGHRSLMYDLRLILKT
                     FYVIVKPNGAY"
     gene            complement(1706..2470)
                     /locus_tag="LP386_001030"
     CDS             complement(1706..2470)
                     /locus_tag="LP386_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HBL1918281.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEWLFFELLELGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQITAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIVKDFG
                     KEKVVQMKQVAKDLINGDEISYPIYEEVKKKKFGLF"
     gene            complement(2498..3196)
                     /locus_tag="LP386_001031"
     CDS             complement(2498..3196)
                     /locus_tag="LP386_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HBL1918282.1"
                     /translation="MARTQKQKAAQTHVVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTIAANIAVVFAKSGQRVLLVDADLRKPVVYETFQLNNAS
                     GLSTALSSSGSVADEIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLTKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYRN"
     gene            complement(3208..3987)
                     /locus_tag="LP386_001032"
     CDS             complement(3208..3987)
                     /locus_tag="LP386_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HBL1918283.1"
                     /translation="MEETISLKEIFGTLRKHLATIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSENSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGSAPARPKATNDKTAPSRRSRSRV"
     gene            complement(4003..4947)
                     /locus_tag="LP386_001033"
     CDS             complement(4003..4947)
                     /locus_tag="LP386_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBL1918284.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFTIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            complement(4993..5772)
                     /locus_tag="LP386_001034"
     CDS             complement(4993..5772)
                     /locus_tag="LP386_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918285.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKIFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVIIKERVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKISVAYATKAQTVAQQMGYSNINY"
     gene            complement(6157..8232)
                     /locus_tag="LP386_001035"
     CDS             complement(6157..8232)
                     /locus_tag="LP386_001035"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBL1918286.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKESKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDYEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTYHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDADRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(8234..9151)
                     /gene="glyQ"
                     /locus_tag="LP386_001036"
     CDS             complement(8234..9151)
                     /gene="glyQ"
                     /locus_tag="LP386_001036"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HBL1918287.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPETVKEAE"
     gene            complement(9537..10349)
                     /gene="recO"
                     /locus_tag="LP386_001037"
     CDS             complement(9537..10349)
                     /gene="recO"
                     /locus_tag="LP386_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HBL1918288.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICERHWSMDDHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRELIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKDMSEKDLPKKEE"
     gene            complement(10492..11391)
                     /gene="era"
                     /locus_tag="LP386_001038"
     CDS             complement(10492..11391)
                     /gene="era"
                     /locus_tag="LP386_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HBL1918289.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(11406..11801)
                     /locus_tag="LP386_001039"
     CDS             complement(11406..11801)
                     /locus_tag="LP386_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HBL1918290.1"
                     /translation="MDLKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIVGLILFVPKIYHLLFN"
     gene            complement(11785..12261)
                     /gene="ybeY"
                     /locus_tag="LP386_001040"
     CDS             complement(11785..12261)
                     /gene="ybeY"
                     /locus_tag="LP386_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HBL1918291.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLELPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISTER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(12290..14482)
                     /locus_tag="LP386_001041"
     CDS             complement(12290..14482)
                     /locus_tag="LP386_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HBL1918292.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIVCGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNDKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSVV
                     LMKFFQLFQTEQAAYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTVILMSYVFSGLMATIVRRKRISEQGLFAAMWVIIFPVMMDVILIIYQGMSFGD
                     ATTWLTLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICRQHHGTTLMRYFYVKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKSEVEKIKEEQEE"
     gene            complement(14506..15477)
                     /locus_tag="LP386_001042"
     CDS             complement(14506..15477)
                     /locus_tag="LP386_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HBL1918293.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            16183..17562
                     /gene="brnQ"
                     /locus_tag="LP386_001043"
     CDS             16183..17562
                     /gene="brnQ"
                     /locus_tag="LP386_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBL1918294.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGTNWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            complement(17718..18164)
                     /locus_tag="LP386_001044"
     CDS             complement(17718..18164)
                     /locus_tag="LP386_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HBL1918295.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(18191..18367)
                     /locus_tag="LP386_001045"
     CDS             complement(18191..18367)
                     /locus_tag="LP386_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HBL1918296.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            complement(18529..18957)
                     /locus_tag="LP386_001046"
     CDS             complement(18529..18957)
                     /locus_tag="LP386_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBL1918297.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            19049..19909
                     /locus_tag="LP386_001047"
     CDS             19049..19909
                     /locus_tag="LP386_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HBL1918298.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPSVEFNLFRRT
                     FVTDEKTLMQALQDALEEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            complement(20004..20354)
                     /locus_tag="LP386_001048"
     CDS             complement(20004..20354)
                     /locus_tag="LP386_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBL1918299.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKTKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(20370..22097)
                     /locus_tag="LP386_001049"
     CDS             complement(20370..22097)
                     /locus_tag="LP386_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBL1918300.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     AIIQKMTEE"
     gene            complement(22311..23237)
                     /gene="trxB"
                     /locus_tag="LP386_001050"
     CDS             complement(22311..23237)
                     /gene="trxB"
                     /locus_tag="LP386_001050"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBL1918301.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            complement(23382..24818)
                     /locus_tag="LP386_001051"
     CDS             complement(23382..24818)
                     /locus_tag="LP386_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBL1918302.1"
                     /translation="MMGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFP
                     VITGKKKMFEFDENHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGD
                     EKEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENL
                     CRVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASA
                     IATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPA
                     YALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFAS
                     VKNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDY
                     RIDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGN
                     GTLARSKKKSFNWYKKVIDSNGENLSND"
     gene            complement(24815..26218)
                     /locus_tag="LP386_001052"
     CDS             complement(24815..26218)
                     /locus_tag="LP386_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBL1918303.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPTMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            26448..27350
                     /locus_tag="LP386_001053"
     CDS             26448..27350
                     /locus_tag="LP386_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL1918304.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            complement(27391..29277)
                     /locus_tag="LP386_001054"
     CDS             complement(27391..29277)
                     /locus_tag="LP386_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL1918305.1"
                     /translation="MGKYQELASKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGVVTVMRAGGQYQVVIGNHVPVVFEEVIRAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTALLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPAFTFATDILMAGFETLLALSPVIYGAIVGFFWQILMMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGNLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEADETDDRQKTSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSEAGLELLIHVGLDTVQLEGKYFKSL
                     VQQGERVKQGDLLLRFDKKKIEEEGYSLETPVIVTNYTDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(29373..30224)
                     /locus_tag="LP386_001055"
     CDS             complement(29373..30224)
                     /locus_tag="LP386_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL1918306.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSEQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGEKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELYQVIQKKYKDTFGCVEKIADFLAEIFNYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            complement(30681..32465)
                     /locus_tag="LP386_001056"
     CDS             complement(30681..32465)
                     /locus_tag="LP386_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1918307.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEKYAPQQNPGADQTITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPTITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLTKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            complement(32465..34216)
                     /locus_tag="LP386_001057"
     CDS             complement(32465..34216)
                     /locus_tag="LP386_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1918308.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAALLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFVIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQQLEAKIEGGEA"
     gene            complement(34358..34582)
                     /locus_tag="LP386_001058"
     CDS             complement(34358..34582)
                     /locus_tag="LP386_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HBL1918309.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            34833..36419
                     /locus_tag="LP386_001059"
     CDS             34833..36419
                     /locus_tag="LP386_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HBL1918310.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFVVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADQIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETIEEIE"
     gene            complement(36729..38504)
                     /locus_tag="LP386_001060"
     CDS             complement(36729..38504)
                     /locus_tag="LP386_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HBL1918311.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIAVLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIHYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     ILASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYSSRRKLLPWFLGLAVSFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEAKKLKERPFLLSKQEWLKLSLFLLPLVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALDASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYQKGT
                     IKKKKEFYLMGSGDGKTMNDLPIVFAFLKSGYAYAWRYKDFHQGGNYSFGTQEQVEQA
                     QELLNLPLMDNWIDSSDPRTPDFQLTKTAKVANVMIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(38715..39617)
                     /locus_tag="LP386_001061"
     CDS             complement(38715..39617)
                     /locus_tag="LP386_001061"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HBL1918312.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAFMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGAEGGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKVIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQAFDPEVFPELLAEEVTL"
     gene            39896..42241
                     /locus_tag="LP386_001062"
     CDS             39896..42241
                     /locus_tag="LP386_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBL1918313.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKVIFRVFQSLTVFITVLLLLFAA
                     LGIGIGAGYFAYLVEDTQLPTKKELQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIVLSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSEAYYQKAQQTIQNKGYTIHSTIDKDIYAALQTGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLVGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINEKITTPFKDVISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSQARIRSANYLANLINQAY
                     QANPEIFGTDEKFDLSSDVMKKKVSGFTGQTAGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANPETKESDDKDD"
     gene            complement(42404..42670)
                     /locus_tag="LP386_001063"
     CDS             complement(42404..42670)
                     /locus_tag="LP386_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918314.1"
                     /translation="MNEFLMQLLKELEKNLHRSNVRSVGMGISQQIWAEKRLTDQNHQ
                     MTAEEAAQEFSNRHVHLKESVKGQFAEKLTELFQRQEKKLKQFR"
     gene            complement(42663..42986)
                     /locus_tag="LP386_001064"
     CDS             complement(42663..42986)
                     /locus_tag="LP386_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918315.1"
                     /translation="MKLEELERDYRSERRQLEAQEDELIHFKNQGLRLMEQEEQRLHH
                     VLKNLALDNEPLFQARRSYSNYQEHYQQALQVERRKLYQQQDELERSYRQKIRQITME
                     KSSYE"
     gene            complement(42998..43204)
                     /locus_tag="LP386_001065"
     CDS             complement(42998..43204)
                     /locus_tag="LP386_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918316.1"
                     /translation="MTEQEIIEALASVVATKENLVDSAKEVYLLRINKARRMGEAFDT
                     LVKEIQDKINEIVTRDRELAQQFN"
     gene            complement(43201..44256)
                     /locus_tag="LP386_001066"
     CDS             complement(43201..44256)
                     /locus_tag="LP386_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HBL1918317.1"
                     /translation="MMADKQYSVISEAVYWLDPKHRDYDHTYKENSIKKIDSYNFKIL
                     KIKDSLDGMQAMGVAPIKNGKVDLSQVVIAFAGTNLSDWKDLETDARSIMNLYGNRPG
                     ASFSEKATTNKILSVSGLKTAGQINSAIAFANEVKKEYGEAAISTTGHSLGGFLALYV
                     AAEKQWKNVGLNGPDPYDLLSPEAKKWVEENPGMLTNYRNHADFIGNFGGNGTGAEVR
                     ISMETAFLNLLASHSLTSWKFDENGKLIIPENENNVKARKQQKENQATQLFSYQLQEL
                     NNIRKKLRLSGGRLTVNEQIYLDDTQARLVVEKLSAKMKSAMEEVIRINQRGIFELEK
                     KWHGKKACGKHVLSPLR"
     gene            complement(44256..44651)
                     /locus_tag="LP386_001067"
     CDS             complement(44256..44651)
                     /locus_tag="LP386_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918318.1"
                     /translation="MSRKIRKLSLAILLIVILGIGGKVYMDKREAQRQKDLLAVEKQS
                     VKVLKNTFADIKEVKIEKSARNEMTGAYRMFVTMINNHDESVYFTFGFWKERNELGDY
                     GVENKSIQKEGITVNKIRVIFSNNKEEYI"
     gene            complement(44694..44948)
                     /locus_tag="LP386_001068"
     CDS             complement(44694..44948)
                     /locus_tag="LP386_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918319.1"
                     /translation="MTVKDEEYRYISEHVYWLDPKHPQYSKSYKEGAIKNFGETKFQI
                     LKIKDSLDGMQAMAAAPIVHSKLEKNFKNKKIPTNFRVLK"
     gene            complement(44945..45340)
                     /locus_tag="LP386_001069"
     CDS             complement(44945..45340)
                     /locus_tag="LP386_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918320.1"
                     /translation="MPKKRRKTIVIILTILAIGIGGKFYMDKREAQRQKDLLAVEKQS
                     VKVLKNTFADIREVKVEEFKKNPVTGCYGALVTMTNNEGKSVYFDYFFSKQMNEISSY
                     GVENEEIQNEGVTTPKIRVIYSNGEAEEV"
     gene            complement(45694..46695)
                     /gene="ccpA"
                     /locus_tag="LP386_001070"
     CDS             complement(45694..46695)
                     /gene="ccpA"
                     /locus_tag="LP386_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HBL1918321.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            46905..48008
                     /locus_tag="LP386_001071"
     CDS             46905..48008
                     /locus_tag="LP386_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBL1918322.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVDRFDAISDILTGADSYTDLTSIIQRLQLIKTVEEKDKLIEAGKWADVAF
                     EIGFKTVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGSTKVSP
                     NELVLFDLGVVWNGYCSDATRTVAYQKPTEFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLE"
     gene            complement(48070..48672)
                     /locus_tag="LP386_001072"
     CDS             complement(48070..48672)
                     /locus_tag="LP386_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBL1918323.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSAELTGIAKEKAQDLSQQAGDLAGNVKQKVSESAEEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDLKKPADELGSIAKDTSEDIMIDVKDAADKAGETVNEG
                     MSEAKPVADDTKEMLKMAKEDAKEAKKEMKDTMTDSTTNH"
     gene            complement(48675..49115)
                     /locus_tag="LP386_001073"
     CDS             complement(48675..49115)
                     /locus_tag="LP386_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HBL1918324.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIIRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIVTKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            complement(49241..50179)
                     /gene="galU"
                     /locus_tag="LP386_001074"
     CDS             complement(49241..50179)
                     /gene="galU"
                     /locus_tag="LP386_001074"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBL1918325.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKIELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYIMSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            complement(50194..51219)
                     /locus_tag="LP386_001075"
     CDS             complement(50194..51219)
                     /locus_tag="LP386_001075"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBL1918326.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHHLPDSIRAFTDMEDAVKDADAVLFVIPTKAIRSVAKELVAKLNTKPVI
                     IHASKGLEQGTHKRISEILLEEIPTEKRKAVAVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNHYFRIYTNPDVVGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            complement(51263..52093)
                     /locus_tag="LP386_001076"
     CDS             complement(51263..52093)
                     /locus_tag="LP386_001076"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBL1918327.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLVLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLLVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            complement(52108..53046)
                     /locus_tag="LP386_001077"
     CDS             complement(52108..53046)
                     /locus_tag="LP386_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HBL1918328.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            complement(53183..>53371)
                     /locus_tag="LP386_001078"
     CDS             complement(53183..>53371)
                     /locus_tag="LP386_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL1918329.1"
                     /translation="NSNGILRRNGLPKSMDFREVNQTFISSVSNQRNYIPRKSLNYRT
                     PIEIFLSYVQEAFYSSLI"
BASE COUNT        14870 a        11316 c         9454 g        17731 t
ORIGIN      
        1 tatcttaatt atctatccat ttcatcctac gcattcttgc gtaaatacaa ttcactctgt
       61 tgagctgata taaatcattg gtggtacaaa gataaaatga taactgtttc tatacctcca
      121 aaaattccag taaatatatc tatagatagt ttcaaaaaaa attgtcttag tttcataata
      181 tttaagatag tggtacatac tttataacaa cgtacttttc caaatattat tttccgttat
      241 gaacatccaa tatattacaa agtttaaaag tttagatgaa ctataatctt catttctgca
      301 cagtggataa taaattctta tagataaaaa atagcctctt ctaaagtcac aaatacctta
      361 ctcccacatt ttaagtaaac actctgcagc attctctttg ttataaaatg atagatattc
      421 ctcaatttta tctcttatta tgttattatc agttgatacc attccattaa tgtttcagaa
      481 taattacaat attttgggac cggataactc ccttttgctc gtaaccactc atatccgtta
      541 ggattcacta aaagtttacc gtttattttt cgattctttt tttgaaccgt cccatgaaca
      601 taccgattca acaagctaaa ttataaaaat tggtgtgctg tcattatttt ttggaaaatt
      661 tattaatggc tatcaatata cttttgtatc atactaaata gctcgtcagt tcctatatcg
      721 gatataccaa tattaaagca tttagatcat tatatttaag agtggtatca tcccaaaatt
      781 tcgaatattt tcttttatat aagaataatg atactgaatt gccccattca cctttctttt
      841 tttagatttt ctacaagtga ttcaaaccct ccataattac agttattact tttgaaacga
      901 taatatgaac atgtgtaatc ttttttatta acaatccatc attctatccc taactaatat
      961 gctccattgg gcttgacaat aacataaaac gtttttaaaa tcaacctcaa gtcgtacatt
     1021 aaacttcgat gaccgatata ctctaaatcc aactcaacca ttttatggaa actaacatta
     1081 tttctatcac taacttgcca caaacctgaa caaccaggtt ttacatacaa gcgttgaaga
     1141 tcatatctcg tgtactcagc tacttccctc tccaaaggtg gccgtggacc aattagactc
     1201 atatcgcctt ttaaaacatt ccatagctgt ggcaattcat caatgctttt ggcacggata
     1261 attttaccta ttttagtgac acgcggatct tctttcatct tgaacattgc accttctatt
     1321 tcattttgat caagtaattc ttccaatttt tcttcagcat ctaaacacat cgaacggaat
     1381 ttatgcattt tgaatgtttt tccattttta ccaacacgtg tatggctaaa aaatattgga
     1441 cttcctggct cttcttttct gattcgataa gctacataga acatcaaagg agaagctaaa
     1501 atcaaaccaa taatgcttcc tacaatatca atcattcttt taaaaaataa atagatatat
     1561 cgtttttcaa ctttttcttt atccaaccaa acttgattag gatgtacttc actaatacga
     1621 gataataaat cttcactttc catactttca gtccctttca ctatcttcac tctctcctca
     1681 tttgttttta tctacgaata aagaactaaa ataaaccaaa cttcttcttt tttacctctt
     1741 catagattgg ataactgatc tcatccccgt tgatcagatc ctttgcgact tgtttcatct
     1801 gtactacttt ttccttacca aagtccttga caatctgctc atagcactct tttaagtaaa
     1861 aggtgcgctt agagaccccg tgtgcatcag aagcagccat ctgcacgaga ttatgtttga
     1921 ccattgtttt ggctgttttc tggatgtctt tgccaaatac accaacataa cttggcgcag
     1981 taatttgggc caaacatccc atatctagga acggaagcaa atgatttggg tcttctcgaa
     2041 aatgcgcgtt gcgttctgga tggacgatca ctggtgtctt tcctagttct aacaactcaa
     2101 aaaaaagcca ttctgcatat aacggcactt ccagtgtcgg aaattcgatc agaagatatg
     2161 tatcatctaa atctgtaaat aaaatttcat ctcggtggat gtcttcgatg agcgttccgg
     2221 taatacgtac ttcttgtcct tccaataacg tcaaaggcaa ctgtcttttc tctaattcgg
     2281 cttgtaacga agcgactaga gaaatgactt gtgatttttc attgctgtat tttccattat
     2341 tgtggtgtgg tgtgcataaa atatgcgtga tgccttgctg aatcgctttt tcagccattg
     2401 caatacttgc ttctaagttt tctgccccgt catcgattcc tggtaggata tggcaatgta
     2461 gatcgatcat ttctcttgtc tcctctcttc ttattcctta atttctgtag taataaccag
     2521 catctttgct atgttctgct ccgttgtata caacacctaa gactcgtgct tgtaccatct
     2581 ctagcagttc ttttgcttta gtcaaggatt ctttacgtga tgtattttca cgtacgacca
     2641 ataaagtgcc atccgttttt gaagacatga tctgtgcatc tgttacggct actactggtg
     2701 gcatgtcgaa gatcactaca tcaaatagtt gtcttgcttc tgctaaaatc tgatccattc
     2761 ttggcgagct taataactct gatggatttg gtggtttagg tccacttggc agaatcgaca
     2821 aattctcgac tggtgttcgt tggatctcat ctgctacact tcctgatgaa ctaagtgctg
     2881 tacttaatcc actggcattg ttcagctgga atgtctcata gacgacgggt ttacgtaaat
     2941 ctgcatcgac tagtagaact cgttgaccgg atttagcaaa aacgactgca atgtttgctg
     3001 caatggtgga ttttccttct ccaggacctg atgaagtcac gacaatcgtt ttgatttgct
     3061 gaccagctgc ggaggcaaac tggatattcg tccggatcgt acgatattgt tcggcgattg
     3121 gtgaagatgg gtttgttaat gtgatcaaac tgactacatg agtttgtgct gctttttgtt
     3181 tctgtgttcg tgccattttt cttcctccta gactcttgag cggcttctgc gtgatggagc
     3241 tgttttatcg tttgtagctt ttggtcgtgc aggagctgat ccttttttac ggataccagc
     3301 gttcaattct ttcgctgaca tttctggaac tgttcctaag attgggaatc ctaatgtatc
     3361 cgtcacatat ttttcatctt tcactgtccg atcaagtaat tcgaataaga atgccaaacc
     3421 tacgcctacc atcattccta atactaagcc aatcactaga ttcaatttat tatttggcga
     3481 aacaggtgtc gtattggcaa ctgcacctga gatgatcgag attttatcga cattcatcac
     3541 gtcttttgcg ttctcttgga aaacttgtga agttgtatta gcgatctgtt gagcagtcac
     3601 tgcattcgtg cttattgcct ggatcgagaa catttgtgag ttttctgact gattgacgga
     3661 gatcgcatct ttgatttgtc cagcggtcat tttcacattg tcttctgttt ctagacgatc
     3721 tttgacttca tttaatacta gatcactaac gatcatatct ttatacgtat tgatcatttg
     3781 caggttcgta ttgacatcat tgacattcgc tgtgtctgat tgcggcagtg tcacgatcaa
     3841 ttgtgcttgt gaactgtatt ttggtgtcaa gatgaaaaat gttacgattc ctgagatggc
     3901 caagccagca aacattgaga tgatgattgt tgccaagtgt ttgcgtaatg ttccaaaaat
     3961 ttctttcaag ctgattgtct cttccatttt ttctccactt tcctatttat tctctagatt
     4021 catttgatct tttaattctt ttttcacacg atcaagttct tgatcgctga ctttttgata
     4081 ggagatatta tcttgcatga agccttctcc ttgcagctga tcttgcttga tcgtaccaaa
     4141 tgcctcccga taatctaaag cgattttttt catttcatca aagctcatgt ctgttttcat
     4201 attcgattct agagcattca aaacggattg atagttgctg acaccgttta gactcaatac
     4261 ttttttcgct acaccttcta cgatctttct ttgacgctct tgtctaccat agtcaccatt
     4321 tggatcttca taacgcatac gagaataaga taatgcctga tccccgttca atgtgatttt
     4381 accgattgta aagtcatagc catcttgtga gaaagtgagg tcattattga cttcgatacc
     4441 accaactgca tcaacaagtt cttttagccc tttcatattg atagagacat agtgatcgat
     4501 tgggatgtct acatattttt gtacggtatc catcgccatg gcagctccgc cgaatgcgta
     4561 agcgtggttg atcttgtctt ttgtgtcacg acctacgatg tcgacatacg tatctcgagg
     4621 aatgctgacg atcgttgtct gtttgtcttc aggactgact gtggcaacca tcatcgtatc
     4681 tgatcttcct tgatcgaccc gacctaaatc tccagtatca atccccatca atagaacaga
     4741 gaaagattct tgtttgtcca gatcaactgg tttcgttcgt tctccttggg ttcgttccac
     4801 tgattcgtaa gttttctcaa tagaatgtga gagatccaga tataattttg ctcctactcc
     4861 tacaattgct aatactaata cgataagaac tgctaaaata atcagaaata tttttttccc
     4921 tcttgatttt cttcttcgtc ttgccatagt ttcctccgtt tgctaacctt gcttgaatca
     4981 tcgctttaac tgtcaatagt ttatattgct atagcccatt tgctgagcaa cagtttgtgc
     5041 ttttgttgcg tatgctacgc ttattttttc attccggatc tgctctattt gactgagcgc
     5101 cgtcaaatat tgatcgtaag tagcggtggc agtcacttga ccatccttta acatcgtatc
     5161 gaataactga tctagttgcg tgacttgcgc gatctgggta tcagcgaatc ctagatattg
     5221 cataacaacc gttttccaag gactatcttt aaaaaagctc atattttcac gtacacgagc
     5281 gacatctgca cttgtcaccc tttctttgat gatgacatcg tctacagctt gctgccagtt
     5341 tgatacattt ttagtaaata aatcgttgac agctgtctgg atcttcagtt ttgattctgc
     5401 actatctaac tgtgtcacga ttgctttctt ctcatcttgg attgcaacag cttctttagg
     5461 caattctgat tctttgatgt cgtaatcatc tgctgaaagt ttgacagagg atagcttatt
     5521 tgacaaactt gtgattgttt cttctgttat ttcagggttt agaaaaattt tttcttttgt
     5581 actatacagc ttgtctactt cttttgataa agaagtcaag gtgtcttttt gattggtgat
     5641 ggcagattct gcataattga tccgttgctg atgttgccgc tgattattga tatggtatcc
     5701 aaacaaacag atcgcaatag cacctgcacc taccgccaca gcagtcaatg acttgacgaa
     5761 tggcttttcc atagattcgc tcctaagtat tgatgataga taaattaaga tataattcac
     5821 ttacataaaa atgacagttt tttatttaaa aaaacataat taaactaata tattcacaga
     5881 aatatttgta aacaagtttt ccctatataa tcataccaca aactgctttc ttgactaggg
     5941 aaatttacga tttaaaagta aataaaacat taataagata acaattaatc gattttactt
     6001 ttatttcctt aattttcata ggtgttttta aaagttacac aaaaaataaa ataacaaaaa
     6061 aaattaacat tgaattaata atagttattt ataacaaata aaccagagaa atagcctatt
     6121 ttgtgcctgt tctctggttt atttacatat tagaaattat tttgtgatga tttgatctaa
     6181 acttgctagt gacaaagcca tggcagcaat ttgacttaat tgcgttaatc ggttcttacg
     6241 tactgctggt tcttctgcca tgaccatcgt ctgatcaaaa taattttcga tcagtgggcg
     6301 aaggcttaca agctgatcat aattttcgtt gatcgtttgg tcagcaaagc ttgttttcat
     6361 tgcctctact gctttgtgca gttctttctc cgcttcgttt tcgaacagtt cagggtctac
     6421 ttctgattgt ttttcaagct ccgctttttt cgctaagttc acgacacgtg tcaaagcttc
     6481 catcgatggt ttgaagtctt catctgcaag atgctgcttg aacaattgtg ctgctgcaaa
     6541 tacttttgtc agatcttttt gttctgcatt caaaacagct tcgatgacat catgacgaat
     6601 attcttcgtt gtcaataatt ggcgcagacg gcctttgata aagtcgatca cctgttgttg
     6661 tcccgctgac aagccaatgc caaaacgatc cgcatcttta ctgataactt cactaatcgt
     6721 ttcttgcaga acagataaag gaaaggccca ttttttcgat tcgatgattc gaacgacacc
     6781 atatgcttga cggcgcaaag catatggatc gtttgagcca cttgggatca tcccaactgc
     6841 aaagaaagaa aagatactat ctaatttatc agcaatcgct aaaacagaac ctactgtagt
     6901 ctcaggtaga tctccttcac tggatatagg catgtaatgt tcacggattg ctgttgctac
     6961 ggctggtttc tcgcctttaa gcagagcata tttttctccc atgatccctt gtagttcagg
     7021 gaattctcct accatgttgg ttactagatc aaatttatag atttcagcag cgcgttgcag
     7081 atccatcaat tcttcctcag atagtcctac ttgctcgcct atgatgcggg cgatgacttg
     7141 tacccgttgc attttctcgt agatgctacc gattttttca tggtaagtaa cagtttttaa
     7201 tttttcaacg tattggtcga ttgaagcttt cttgtcttca ttataaaaga attccgcatc
     7261 ttctaaacga gcagtcaata ctttttgatt gcctcgaacc acattttcca attttacccg
     7321 atcaccatta cgagcagaaa taaaatgagg aagcagcata ccttgatcat tccgtacctc
     7381 gaaataacgt tgatgttctt tcatagaagt gactagtact tcttcaggaa cagaaagata
     7441 tttttcttcg tagtcgccag aaaagacagt tggatattcg actaaattgt tgacttcttc
     7501 tagtaaatct tcgtctagat caataaccca gtgatttttt tctgctaatt cgtttgcttg
     7561 tgtaacgatc atttcttgtc ttttttgcgg agacgcaatg acgaattgtt cattcaattt
     7621 ttcttcatat tcttttgcat gcgcaaatgt cacatcttcg cctaagaaac gatgacctcg
     7681 agaggctctg cctgttttga catccaagat ttcgaatggg attacttcat catctaacaa
     7741 tgccacgatc cagtgaatag ggcggatata ttcaaaatcg tattctgccc aatgcatcgt
     7801 tacagggaaa gtcaggcttt taatgacatc tgctaaacct gtcaatactt ctttggattc
     7861 cttaccatga gtgtatttcg ttacatagac atattccaca ccttttaatt ctctaaaagt
     7921 gatagcgtct gtcgtcagac cttgtccgcg gacaaatcct tccgctgctt tcgtccagtt
     7981 tccatctgcg tccaaagcaa tttttttggc tggtcctttg acttcttctt cactgtccgc
     8041 ttgtcgttct ggaatatttg ttactttgat tgctaaacgg cgcggtgtgg aaaatgtttc
     8101 gatcgtatca taagtcaatt ggttttcatc taaaaatttt gctgtttttt cttctaattg
     8161 tttcatgctt ggtgtgacaa catgggcagg catttcttcc agcccgattt caagtaataa
     8221 gtcttttgcc atcttattca gcctccttca cggtttctgg atttgctgtg tttttattca
     8281 acaaagggaa tcctaatttt tcgcgttctg ccacaaagat tttggctaca gcacgagcca
     8341 tgttgcggat acgggaaaga taaccggcac gctctgttac ggatactgca ccgcgagcat
     8401 ctaataaatt gaatgtatgg ctgcatttca aaatataatc atacgctgga tgaacaagat
     8461 tttcatcgat acagcgttta gcttcttttt caaaacgatc aaagttgctt agtagcaagt
     8521 cttgatcgct tacttcaaaa gaatatttgg aatgttcata ttctggttgt ttgaagatct
     8581 cgccatattt cacgccatca gcccattcta aatcatagac actttcaact tcttggatat
     8641 aagaagcaag acgttctagt ccataagtga tctcagaagt gactggttta caaggcagtc
     8701 caccaacttg ctggaagtac gtgaattgtg tgatttccat tccgtcaagc catacttccc
     8761 aacccacacc ggcacagccc atggatgggt tctcccagtt gtcttcaaca aaacggatgt
     8821 cgtgttctaa tggatcgatt cctaaaaggc gcaagctttc taaataaagc tcttggatat
     8881 tctcaggtga aggtttcatc acgacttgga attgatgatg ctgatacaaa cggtttgggt
     8941 tttcaccata acgtccatca gctggtcggc gagatggttc tacgtaagca gcattccatg
     9001 gttctggtcc gattgcccgt aaaaaggtat atgggctcat cgtacctgct cctttttctg
     9061 tgtcatacgc ttgcatcagc atgcagccgt ttgatgacca aaatttttgt aatgttaaaa
     9121 tcatatcttg gacggtcaat tttttactca tctgttttgc ccctttcaat tttaaagcgt
     9181 tgctgtcaaa taagaataca ggaaagaaaa cgacaaaaaa tccctatgtc tgattacaga
     9241 catagggacg aataattcgc ggttccaccc tacttccgaa taaagattcg gcagcttcat
     9301 ttatcgtact cgcaagtgcc tcttcaaaaa tcgtttgggt ccggctccca ctctcccgaa
     9361 ctcgctaaac cacgtgtttt ttactgatct tggtcaatgt acgtattcat tttgcagttt
     9421 tcttgtttct ataatagatc ctctcactga acgatctatt tgatctacgg ttaataatag
     9481 acggaactcc ctgtgtttgt caaatggttt tgattttttg ttgtatgttt catttactat
     9541 tcttcttttt taggtagatc tttttcagac atgtctttct ctggcgtctt taatacgtgt
     9601 gcccaagact tcatttgatc gatgaacttt ttgcttttca aatgaatacc gacatattca
     9661 tcatacagct ggtcgatgag ttcacggatt gcttgtttgg tttcttcttt cagatggatt
     9721 ccactgattt tatcataaga aatagctgaa aacatccgaa cgaaataaac agctcgagga
     9781 tctgcatgat aacggtgatc gtccatcgac caatgtcttt cgcatatcac accaccatat
     9841 ttggaagaat agtcaaattt tccttttgtt tccccacata cgacgcagtg tgtccagatt
     9901 ggtgcaattc cgaagcgttg cagtatttga acttcaaaga tattcgtgat gatttctgca
     9961 tcatctcctt gatccatccg ctgcagagct tgttgcgtaa attggaataa atgcgggtca
    10021 tattgatgat cttcgattgc tgcatctact agatttagca aataggtacc ataaccgctc
    10081 aaaaagatat cttcttggat gttccgaaac gcatggacgt ctttgacact gcttaaaaac
    10141 gacaaacctt cacttcgaaa attaccgata tagactgctt cggtaaaggg gagcaaagcc
    10201 ggagctaatg gctgattttg ccgatggatt cctttgatat aaaacatcat tttgccagaa
    10261 gattccgtaa agattttgac taatttatct ttttctttgt aattacggct agataaaatc
    10321 aagcctttcg attctgcaag ctggctcata ttctccctcc taaaaaataa atctggaaaa
    10381 gcagattctg ccgatccaga ttatttatgt ttcgatcttc cgccgttttt ctcaacgtgc
    10441 ggatttttat ccagtttatt tctatactta acctataaga agttcagaat atcagtattc
    10501 atcttttcgg tagccgaagt cttgcagata gacttttttg tctcgccagt ctttttggac
    10561 tttgacccaa agttctagaa atactttgtc tcctaaaaga ttttcgatat cctttcttgc
    10621 tttcgttcct acttgcttca gcatttttcc gcctttgccg ataatgattc ctttttggct
    10681 atctctttcg acgatgatcg tggcctggat atggatttta tcattctcgt ttcgcttcat
    10741 cgaatcaaca acgactgcga cagaatgagg cacttcgtct cgtgttaaaa acaagacttt
    10801 ctcacggatc aattcagaaa cgatgaagta ttcaggatga tcagtcactt gatcatctgg
    10861 aaaatattgt gggccctctg gcatttcact gactaataca tccatcaaac gttcgacgtt
    10921 gtttccttct gtagcagaaa ttggaatcac ttgtgcaaag ggcatctgcg ttgaataatc
    10981 ttcgatgatt cccaacaact cgtctggatg gattttatcg attttattga taatcagata
    11041 aacaggagaa tgcacgtttt ttagacgttc aataataaaa tcgtctcccc ggccgcgttt
    11101 ttgatcagcg ctgatcataa ataagaccgc gtccacttct ttcaacgcac tgtaagctgc
    11161 ttctaccata aaatctccta aacgatgctt tggtttatgg attcctggtg tgtcaataaa
    11221 aatcaactga gcttctggtg tagtatatac tccttggatt ttatttctag ttgtctgcgc
    11281 cttatcactc atgatggcaa ttttttgacc cacgattcga ttcaataatg tggattttcc
    11341 tacattcggg cggccgacga ttgcgacaaa ccctgattta tgttctggca tatacgttct
    11401 cctttttaat taaacaacaa atgatatatt ttagggacaa ataaaatcaa cccaacgatg
    11461 acggcaaaac aagcggtcac taaaactgct ccagctgcca tatctttgat ttttttccca
    11521 atcggatgaa aatgaaaatc cgtaaacatg tctacgacat tttcaaaaac agtattgatg
    11581 atctctacta tccatacgag aaaaacagct aaaagcagcc ataaccattc tatccgatca
    11641 agttggaaaa tcacgcccat aaacaaagcg aggattccga acgcaacatg tttcctcatg
    11701 ttgcgttctt cctcaaaaac agttttgact ccttggacgg caaattccac ggacatcagg
    11761 aaatgtttgt ttttctctac gtttttatct tttaagtcca taggcatcta agatctcttt
    11821 ctgtaaacca aacatttctt tctcatcctc tggtgtcata tggtcatacc cgttgatatg
    11881 caagaatcca tgaaccgcta aaaagccaag ttcccgatca tacgaatggc cgtaagcttc
    11941 tgcttgctct gcagcacgtt cagtagagat catgatgtct cccagtacac gaggcaatgg
    12001 attctctcca tcttcaaaaa tcactgggat ttcgtcttca ccctcttctt ccaaggcaaa
    12061 actgatgacg tctgtcggtg catcttttcc acggtaatca cgattgatta cttggatcgc
    12121 tgcgttgtcc atgaaagtaa cagacatttc tgtttcttct ggcaactcta aatatgatgc
    12181 tgcaaattgc aacaagtcgt cgatttcttt cattttctct tctgagactt ggtttgtttc
    12241 atccatgaag gtaatatcca ttatacatcg cttctttcta ttcttcttgc tattcttctt
    12301 gttcttcttt tatcttctca acttccgatt tcattttagg atatttgatc cgagaatgga
    12361 aggtactgct taaaccgctg atcaatgatt tttctacttt acggatttct tttaacgtca
    12421 atccactgtc atccaattgt ccatcggaaa tacgctcttc tataagatta tggacaaaac
    12481 tttcgatttt ttcgcttgtt ggatggtcca ttgcccgtac tgccgcttca caactgtcag
    12541 ctatattgac gattcctgct tcacggcttt gaggttttgg tccaggataa cggaattgct
    12601 cttccgtgac ttccgggttg cgttcctttg ccttaacgta gaaataacgc atcagcgtgg
    12661 ttccatgatg ctgtctgcaa atatcgatca ccatttgcgg catattataa tcttccaata
    12721 ttttggcacc atctgtcaca tgtccaaaga taatatgttt actgtcttct ggcaataaga
    12781 aattgtgcgg attttccgct cctgaaggca agttctcaac gaaaaagctg gcgtgtttga
    12841 tcttgccgat atcatgataa tagcaagcta ctcgagttag taaagaacgt ccaccgattt
    12901 ctgctacagc attagcactt agattggcta ccatcatgct atgatgatac gtacctggtg
    12961 cttcttctaa caactgtttc aataaagggt gattaggatt gctgagttca tttaatacga
    13021 tcacactatc atcattgacc atcaattcaa tataggggtg cagacctatc gtcagcaaga
    13081 atgagaacaa tgcacctgtg aatccgcaga ctagcgttaa ccaagtcgtt gcatccccaa
    13141 agctcattcc ttggtagata atcaaaatga catccatcat cacagggaaa ataatgaccc
    13201 acatagcagc gaataaccct tgttctgaga tccgtttgcg tctgacgatc gttgccatga
    13261 gaccagaaaa tacataggac atcaaaataa ctgtcagaaa gttcgtgcca atcgaatcat
    13321 aaaaaatgaa aagtgcggat actgcttgga aaataccagc catgatccct gctcttcgat
    13381 tcaagaaaaa gcttaaaaca agtggagcaa aagccgcggg gtaaaacagc ggaatataag
    13441 cagcttgttc tgtttggaag agttggaaaa atttcattag tactacgctg actgacattg
    13501 ctgtcacgta gaaaagtacg tattttgttc tttctcctgc attttgaaat tgaagtgaat
    13561 tataaatcag tacaccgatt tgaagcaaaa cagctaaaac catggcaatg agtgggaaaa
    13621 tcgaagtcgt ttgattcgtc aatcctagta attccaattt tttcatcgct gaagcatcaa
    13681 tttgatttcc ttcgcgaaca atgatttctc cttggaagat catcactggt tgtacagctt
    13741 ctcgtgcaga ttgttttaat tcttctgtct ttttctcatt caatacatca ttgactacaa
    13801 tgccttgatc cactaagtag cggatcattt gttgctgctc tgttgtgaca ttcaaatact
    13861 gaatctgatc ttctgcttct tgtttaaaag cttccaattc gctttcacga acttgtttac
    13921 tcatctgttc gtcaatgagc ttcaaacttt catccctaac cgtgtgaatt tccgtttcag
    13981 tcatttcaaa tatcgtcgaa taaaaattgt tcggcagttt ttggtaaaac gcaacgtttt
    14041 ctgcattcac gttttcaaaa tttttcttca gtgtagcaat ccgctcttct gtagtaggtt
    14101 tcgggatatt ttcatcttcc ttcgccttat ctaccttgtc attataagat ttgttgatgg
    14161 tatcattcgt cttatcgatc aattcgaata attgcttgat ccgattgttc tggtcatctg
    14221 ccagatcttt ttgataagta tattctggag tcactgcttc tgctgctagt tttcttcttt
    14281 gttcggtttc ttccgtgttc tcgatcgttt tattcgcacg gatactctct tctgctactt
    14341 ggccttctct aaaatcattg gccttttgtt tgacactact aaatgtaacg ccgcaaacaa
    14401 tgataaaaaa caagaacaga aggaaaggca atgctgcctt tccgagtttt tcttgtagtt
    14461 tctgcagtgt tttattcaac atgtgcttat cctcctaagc aaagcttatt cttgatgaag
    14521 atccgccttt tcataagctt tgatgatttc ggcaactaca gggtgccgaa caacgtcact
    14581 tgcttcaaaa ttaacaaaat cgattttttt gatttgcttt agtgttcgtt ctgcatgaac
    14641 aagaccactt gtcgtccctc gaggcaagtc tatctgactt gtatccccat tgacaatcat
    14701 ttttgattga taaccgagac gggtcaagaa cattttcatc tgagcgactg tcgtgttttg
    14761 tgcttcgtcc aagataacga atgcatcatc caatgtccgc ccccgcatgt aagctaatgg
    14821 tgcgatttcg attacgcctc gttccatcaa tcggttcgta tgatccaatc caaaaatttg
    14881 gtataaagca tcataaacag gccgcagata aggatccact ttttctttca gatcccctgg
    14941 tagaaagcct aggttttccc ctgcctctac agcgggccgc gtcaaaatga ttttttgcac
    15001 ttcgcctttt tttaaggcag caattgctaa tactacggca agaaacgttt tccctgttcc
    15061 ggctggccct acaccaaata cgatgtcatg tttggctacc gattcaacat atttcttttg
    15121 accgctgttt tttacccgta taggttttcc attacggtct ttgacgatct cttcctcata
    15181 catctcaaca aaataatcta atgtaccttt ttgccccatt ttcaatgccg tcacaacatc
    15241 gggcgtactt acgtggattc ctcgtttgat caattcctgt aatgtccgaa tgactgaggc
    15301 agccaaggaa atctgggatt gttcaccaat gatctgaatg atttctccac gtgtatggat
    15361 ggttgtttcc gttgtttcct cgatcagttt tatatgcttg tcgtgtgcac ctaaaagcat
    15421 gctgacatca tcagcagctg tcaatctaat ctctaaagaa ctagactctt ccgtcaaaaa
    15481 tagacatccc ctttttttcg attcattctt tcctatttta ccatactcag aagaaactat
    15541 atagcaaata agaaaaggtt gtaaaagagt cgtttaacca tacgtaccaa gaaacgttaa
    15601 aaaatagccg tttccattcg ctaaaggtct cgttttgata aaaagaatct gagaatgtaa
    15661 gttatatgaa agtggagaac aaaatattcc gtttcattca gcaggtattc tctaggtatt
    15721 tttcttgttt caaaaaaaga aaacaaaata gttaaaatat tcttgcattt caaaaaaaac
    15781 aggtgtatta ttacgtcaac aaataaacat acagcaaagc gtcgaggaaa acagtaggct
    15841 attcaacgat ttattcccag tgagtcatgt aagtgagaaa tgacaataaa tcgaatagac
    15901 gaacatcatt tccgagtcaa tgtcgaaaac gtagatcatt gtggctgcct ccattatcag
    15961 gctagcggat aactttatca aaaagcgtcc gtgaatgaag aagctttttt aagcgaaaaa
    16021 aggtggtacc gttctagaat ctagagccct tttcccaagt ggaaaagggc tttttttata
    16081 ttttaaggtg gtggttttca tggaatctga tattaatggc attactaatt gctgcaacgt
    16141 ttatatcgtc aatcaaaatg ataattattg gaggaaaaat ttatggaaga aacaaaaact
    16201 tattcatgga aacaactatt gatggtcagt tcacttatct tcgggatgtt cttcgggtca
    16261 ggtaatctaa tctttcctgt ccacttaggt caaatggctg gcacaaactg ggtcagtgct
    16321 ggcgtaggat ttgccatctc aggcgctctt ttcccattac tagctatctt agctgtagta
    16381 gtgacaaaaa gtgatggtct gtatgactta gctaaacctg tcggaaaatg gtatgctgcc
    16441 ttgttcttaa tccttgttca tttgacgatc ggaccatttt tcggtacacc acggacagct
    16501 gctactgctt ttgaaatggc tgctaaacca tttttgcctg aaaaatataa ttcattaggt
    16561 atgtttttat tctctgctct tttcttttta cttgcttatt tccttactgt ccatcccaca
    16621 cggttggtca aatacgtcgg aaagtatcta aactccttgt ttcttgcatt attagcaatc
    16681 atttttgtcg tttctttatt ccacccaatg ggaaatctaa atcaatctgc tgcagatact
    16741 taccaaacaa acgctttaac aaatggtgtc ctagaaggtt ataacacggt tgatgcagta
    16801 gctttgcttg ccttaagtgt cacttttgtc catgcagtcc gtgaccttgg tttcaaagat
    16861 aaaaaagtca cagaattaac agcaaaagct ggtagcctga gcgttgcgct agaagtcatg
    16921 atctattttg gacttgttct tctcggtgcg atgagtttga ataagatgtc tttatcagaa
    16981 aatggcggaa ctgcactttc tcagattact aatttttatt taggtaactt cggcgctagc
    17041 ttcttaggag tgatggtcac attaggtgtc ttcactaccg ctatgggact cgttgtttct
    17101 tttgcacaag atttccataa actgttccct aaagtcagtt atatgacatg gctgcggtta
    17161 acgactttcg tctcttttgt cgttgcaaat gctggtttgg acaatatcat ccaatggtct
    17221 ttaccagtat tgatgctttt gtacccattg tcgcttgcgt tgatcttgct ttccttaaca
    17281 gcaaaatttt tccaaaagac accatttgtc tatcaagtaa cgatgttgtt tgctgctgtt
    17341 cccgccgtat tggatatgct ggcaaattcg cctgctttag tgagtcaaca aagagttgta
    17401 gcaagcatgc tcgaatttta tcatcatcac gttccttttg ctgcattagg acttggctgg
    17461 atggtcccaa cgttacttgg ttacgctggc agcttactct tctattacgc ctatcgccta
    17521 tcagggtaca aacaagaagc aaatgaacta ccagaagaat aaccagatca aacacaattt
    17581 aacataagaa atattaaaca ggaaaaaacc agctagatga aagaatccta ttctttcgtc
    17641 tagctatttt ttagatttct tttttacgag cacaaaaaaa ctgcggacaa tgattgtccg
    17701 cagtttaaat gataaaatta agattgtaat agttctttca caatggcatt tacttggttt
    17761 ccatctgctt ttcctttgac tttaggcatg atcgcaccca tgactttgcc aaattctttc
    17821 attgatgaag caccagtttg tgtgattgct tcttgaacaa gttgtcgaat ttcttcgtcg
    17881 gaaagttgtt ccggcatgta tttttcgact atcacaattt cactttttac tttttcagct
    17941 aaatcgtcac gtcctgcttc ttcaaactca tgcaaagaat cacgtcgctg tttcatttcg
    18001 cgagacaaca ccgttaattc ttcttcttct gtcaagtcgt gaccttcttt aatctgctcg
    18061 ttttgtatag atgacttgat cattcggatg acttgtaaag attccttatc tttcgctttc
    18121 atcgctgttt tcatgtcatc gtttaatcta cttagtagtg acacactacc aactccaatt
    18181 catcacagaa ctagaatttt ttgcgttttc tagctgcttc agattttttc ttgcgtctta
    18241 cacttggttt ttcgtagaat tcacgtttac gagattcttg taaagtaccc gcttttgaca
    18301 cggaacgttt gaagcgacga agagcatcgt caagtgattc gtttttgcga acgactgttt
    18361 ttgacatgtt aattccctcc ctccgagctt aaaaagtaac cgtaattgtt attgaaatat
    18421 atctcaaaaa acaagactgt cctgtaaaca ttatatctaa tgctgttttg accgtcaagg
    18481 aaatcttgct tttttttaaa attatcaaat gttattttat ttaaatcctt attgacaatt
    18541 ttcacatctt ccgaaaatct cgaatctatg cccttcgatc gtacatccac cgagctgttc
    18601 ttcgaaataa ttcattggac acatatggat ttctttcgtt gttccgcaca ccgtacagat
    18661 aaagtgatgg tgatggccga tttccccttg acagcaatga aaacgaaact tcatctctcc
    18721 atttaaatcg gtttcttcca gtaaatcgat ttctgcaaaa tcatggagat ttcgataaat
    18781 cgtatcgtaa cttactcctt tgaattcctg attcatatag tcaaaaactt ctttagcgga
    18841 tacgtagcga ttgcgcttca ctaaataagt taacaatgct tctctttttt tagtatattt
    18901 aaaaccgtta tttttcaatg tttctagtga ttgttcgatc aatgtctgtt ttttcatgac
    18961 ttattcctcc aaatcaaaat gattacgaag tacacattct agagtatggt ataataaaca
    19021 taaaaaaaat gcaagtgagg ttttatccat gtcttccgat tctacagaaa tcgttacttt
    19081 ttttgtcatc tccgactctg ctggagaaac tgcgacaaaa ttagcgcaag ccactatggc
    19141 ccaatatcct agcgttgagt tcaatttatt ccgcagaaca tttgtgacag atgagaaaac
    19201 attgatgcag gcactgcaag atgcactaga agaaaaagct cttgtcttac acacattgat
    19261 caatcaagaa ttgatcgaga tgacgcgttc tttttgtgaa gaacatcaat tatttagttt
    19321 tgatgtgatg actccgccga tatcagaaat cgagcgctta actggtatca agcccattcg
    19381 gcaacctggc gcccttcatt tattgaatga gaactatttc aaacggatta aagcaatgga
    19441 atttgctgta aaatacgatg acgggaaaga tcctcgtggg tttctagaag cagatgtcgt
    19501 tttgctaggc gtatcccgaa cttccaaaac gcctttgagc ttgtttttag ctaacaaaaa
    19561 tttaaaagtt gccaatcttc ctttgatccc acaagcacat attcccaaac agctttggga
    19621 gattgatcct aaaaaaatcg tgggattgac gaataaccca gatattttaa acaatatccg
    19681 taaagaacgg atgcgctctt acggattaaa tcctgatact gcttattctg atatcgaaaa
    19741 aatacgagct gaactcgatt ttgcaaatga tctttatgaa aaactgggct gcgtagtaat
    19801 caatgtcgct tctttatcta ttgaagaaac agcttcgctt attttgaatg ctttagacct
    19861 agaagatcat agttattatg gaactgaaac caccgaagaa acagactaac agtttttctt
    19921 gtctttttct taaaaaaaac tggactgtgt cagcgaagaa gattcgttga cacagtccag
    19981 tttgtctcta tttgcaccta tcgttattga tgttccacat gtttgagtgt ctggttcaaa
    20041 atatccagta cgtgagaatc atcaagacta tacaaaatcg cttttccctc acgatgggac
    20101 ttgacgacat ggttttctct taataaacgc agttgatgcg atacagcaga ttgttccatt
    20161 tccactgctt gggtgattgc tgtcacattt tgttccccgt ctttcagata cagcagaatt
    20221 ttgagacgag tggggtcact caacattttg aatagttggc tgactttctc tacttttgtt
    20281 ttttgcgtgt ctggcaatcc attcacctcc aacttgaaaa aagactgact tctaaagttt
    20341 accacttttt ccatcagtct caagtttttt tattcttctg tcatcttttg gataatcgct
    20401 tcataagcgg ctactttttc agctgcgtct tctgaagagt ttccttttac accgatgtaa
    20461 aatttgattt tcggctcagt tcctgaagga cggatagcga tccagccatt ttcttccagc
    20521 gtatacttca atacatcaga tggcggtgtc gttagttttt ctacgtttcc ttcacggtct
    20581 gttctcgtca actctttgaa gtcttctgtt tggatgactt ttgctccggc aaattctgtt
    20641 ggtgcttctt cacggaattt ttccatcaaa gcagagattt tcgcagaacc ttcttgtccg
    20701 ctcattgtca cagaaatcgt tttttctgcg tagtagccat aggtttcaaa aatcgtttgc
    20761 aagccgtcat acaacgtttt gccttgtttt ttatagtaag ctgctacttc tgctaataag
    20821 agcaatgctt ggatcgcgtc tttgtcgcga acgaaaggtt taactaaata accgtaactt
    20881 tcttcgaatc cgaacataaa agtatgggaa tgatcttctt caaattgttg aattttttca
    20941 gcaatgaatt tgaatcctgt caatacattg aacatggtag ccccatagtg ttccgcaatt
    21001 gctgtaggta attcgctaga aacgatcgat ttcaataccg ctgcgttttc aggtaaagtg
    21061 cctcgcgatt ggtgtgcttc caaaatatat tgagcaaaca gtgctccgat ttggtttccg
    21121 gtcaatactt cataggagcc atttggcaaa cgaacggctg cacctaaacg gtctgcatca
    21181 ggatctgttg caatcagcaa atcagcgcct tctttctcgc caagtcgtat cgcatactca
    21241 aaagcagagt gttcttctgg atttggtgat ttgactgtag tgaaatctgg gtctgcgaca
    21301 gcttgttctg gaactagtac gaattgttcg aatccagctt gtttcaacgc acgttcgccc
    21361 aacatttttc ctgttccgtg aagtggtgtg tacacaagtt tcaaatcttt ccccattgtt
    21421 tccaccaatt catgatcaat cgttactgct ttgatttctt ctagataagc ggcatccact
    21481 tcttctccga tgatcgtgat caatccgcta tgttcagctt cttcgtcaga taatacttca
    21541 acttttaacg gattgctgac ttcacggaca tatttcgtca atgcatctgc gtctgcagga
    21601 ggcatttgtc ccccatcttc gccgtagact ttatatccgt tgtaagctgc tggattgtgg
    21661 gatgcagtta ccatgattcc cgcaaacgtc ttcaaatgac ggactgcaaa agaaagctct
    21721 ggtgttggac gtagactttc gaatacataa gatgggatat tgtgatgtgc taatgttttg
    21781 gctgcttcca tggcaaattc tggtgattga tggcgtgagt cataagcgat agcgacacct
    21841 cggcgttttg tttcttcgcc ttgtgtatcc atgaaacgtg caagtccttc tgttgcttgt
    21901 cttaccgtat agatgttcat tcgattgatc ccaggcccta agattccccg catgcctgca
    21961 gtaccgaatt ccaacggtgc ataaaaagca tcttcaagtt tttcaggatc ttcacccaga
    22021 tcatttaatt gtttttttaa gttttcttct aaattttctt catgtaccca ttgttcatac
    22081 acttgttccc aagacatgaa aataacacct ctttctgaaa tatggttctt aataagtata
    22141 gcattcactt attagatata aaagtatgag gaccaaaaaa cgcttaaatc aagaaaggat
    22201 tcttttatca agcacggttg caagtattcg cataaatcgg attcagtaga tttcacgcga
    22261 aaaaaaagag taaaagaaca attgaaaccg ttcttccact ctttttaaac ttatgcagtt
    22321 gtttcttcta aagattccaa gtatttatac acttgttgtc cagcgatccc accatcacca
    22381 acagcagtag tgatttgtcg caaatctttt tcacgaacat ctccgatggc aaaaacgcct
    22441 ggtatattcg tcttcatttc gttgtctgtt ggaatccagc cagcttcgtt cgtcaaccct
    22501 gcttctctaa atggtgcagt taatggatcc agtccaacat agatgaatac tccgtctgct
    22561 gccaaatcaa actcattgcc ggttttgaca ttacgtgctt tcacacctgt cactaccatt
    22621 tcattcccaa cgatttcgtc aacgactgta tcccacataa aggaaatttt ttcattcgca
    22681 aatgcacggt cttggatgat cttttgtgca cgtaattcat ctctacggtg gacgatgact
    22741 acttcagaag caaattgtgt caaatagatg gcttcttcta ctgctgagtc tcctcctccg
    22801 atcactacta gacgtttgtt acggaaaaac gcaccatcac aaactgcaca gtaagaaacg
    22861 ccacgtccag caaattcttc ctcgccaggt acgcctaatt tacggtggat acagcctgtt
    22921 gcgataatga ctgtttttcc ttcgtaagtt ttatcttcac aaataacttc tttgtggctg
    22981 ccgtgatcct tgatatcttg cacgattcca taagcatttt ctgtcccaaa tcttgaaaca
    23041 ccttcataca tcttataagc tagatcagga cccatgattg aatcgaaacc aggatagttt
    23101 tcgatttctg ccgtattgtt catttggccg ccaggggcgc cttgttcgat catcaatacg
    23161 gataagtttg aacgtgaagc atataaagca gcagtcatcc cagcaggacc tgcgccaata
    23221 acgattacat catacatatg tagattctcc tttacttaat caagtaagca tactttacag
    23281 ccaatgcgaa aaaaagtcta ttgttctgct tgcgtttctc gaatagcttt attatactcg
    23341 aaaaatccgc tgaaaaacaa tagactttta taaatcattg atcaatcatt cgaaagattt
    23401 tctccatttg aatcaattac ttttttatac cagttgaatg atttcttctt cgaacgggct
    23461 aatgtgccat ttccctcgtt gtcacgatcg acataaatga atccgtacct tttcttcatc
    23521 tcacctgtac cagctgatac taaatcaata catccccaag tcgtatagcc taatagatcg
    23581 actccatcta attctactgc atctttcatt gcttggatat gtgctgccag atagtcgatt
    23641 cgataatcat cttccacata accattctca tcgggcgtat cgactgcacc taagccgttt
    23701 tctacaataa atagtggttt ttgataacga tcataaatat cattcatcgt tattctcaag
    23761 cctaatggat caatttgcca accccattca cttgcttcca gatatggatt tttgacagaa
    23821 gcaaagatat ttcctgcagt ctgttccaag agttcgttgt cagtagtcga aactcgagaa
    23881 gaataataag aaaaggagat aaaatcaaca gtatgttctt tcagcaatgc ggcatcccca
    23941 ggttccattt cgatctgaat gccatttcgt tccatttctt tcaatgcata agcgggatat
    24001 tctcctcgtg actggacatc aatgaagaaa taattttctc gatctgattt tctagaagcc
    24061 caaacatctt caggattgca agtgtatgga taatatgctc ctgctgccag catacagcct
    24121 actttgttct ccggatctac ttcatgagca atcttcgttg cgatggcact tgcaaccaac
    24181 tcatgatgtg ccgcttgata tttgatttgt tcttcatttt ctccttcttc aaaatacagc
    24241 cctgcgccca tgaatggtgc atgaaggatc atattgatct cattgaatgt caaccaatat
    24301 ttgacaagtc ctttatagcg attgaagatg actcggcaca gattttcata aaaaccaacg
    24361 agttctctgg aacgccacgc accatattct ttgatcaaat gcatcggaca atcaaaatgt
    24421 gtaatcgtca caagcggctc gatcccgtac ttttgacatt ctttaaagac atcctcataa
    24481 aatttcaacc cagattcatt tggctctttt tcatcgccca ttggaaaaat acgactccaa
    24541 gcaatggaca tccgataagt cttgaacccc atttctgcaa ataaagcaat atcttcctta
    24601 taatgatgat acatatcgat cgcaattttt gctggataaa aatgattttc atcaaattca
    24661 aacattttct tttttccagt aatgacagga aaacggtctt ctccgattgg cacaacgtct
    24721 acgttcgcta acccacgtcc gccttcatca taaccgccct cgcattgatt ggctgctgta
    24781 gctccgcccc ataaaaaatc ttttctgaat cccatcatac ttcctccatt acatgtgtat
    24841 tgcttgataa ttctcttgcc agttcatctt ggacttcgat tccttctgct tttaaccggc
    24901 tgattgtttc cttgaattgc ggtaaatact gctgatgtgc aataaacaac tcatccatta
    24961 tccgttttgc tgtctttcct gatcgtataa gcggattgat cgtaaacgct tgcaaagctg
    25021 ttccataatc accagtcacg gctgcttcga tcgtcagcaa ttccatattc ttcattactt
    25081 gcaaccagcc tctttcagca gcaggaaggg aaccaaacgc tacatttcgt gcgccttgtg
    25141 cgccaacata ggcagtgact tctactacac aatctgccgg cagatcagga acagctccat
    25201 cattctttgt agataccacg atctgtgttt ctttatttcc atagatcgaa gcaatcgttt
    25261 cacaggcagc atctgaataa taagcaccac ctcgtttttg caattgttca ggtttatgat
    25321 ccaattctgg atctttgtat aattcaaaca gctctgcttc tgtttctttc acttgctgcg
    25381 ctcttgtacc aatcgtttga tattcttcta aagcatgttc cagcatttct tcttcacggt
    25441 agtaatagcg gtggtagcca caaggaatca tgttcatttg ttttaattgt tctttgaaaa
    25501 acgggatatc aaagatattt ttcggcaatc cattgtcttc atcgtataaa cgatcaatca
    25561 attctgccgt gcggtcattt cctttattat ctgctacttt gtgccaatgg aagtgattta
    25621 gaccggcaaa cttgtagatc agctcttctt ttttcttgcc aagcattgtt ggttctgtca
    25681 tcatcgccat tactggcaca ttgcataatc cgatcacttt atcccatttg ccatatctga
    25741 taactgcttc tgtcaccatc ccgcttgggt tcgcgaaatt gatcagccaa gcatttggac
    25801 ataaacgctt catgtcttca acgattgcca aaaccactgg aacggtacga aaagctttga
    25861 atatcccgcc agcaccattt gtttcttgcc caatcatccc ataataacta gggatccgct
    25921 catctttgat tcgtgcatct aattgaccga cacgaaactg agtcgtaaca aaatccgcat
    25981 ctttcaatgc ttcttcccga tccagagttg catagatttt gacttcatac ggagaagcat
    26041 cccacatacg ctgagacatc tgactgacga tctcaagctt ttcttttcct tcttctacat
    26101 ctacgagcca gatttctcgt atcggtaatt cctcatatct tttgataaat ccttccatca
    26161 actcgggggt gtaactgctg cctccaccaa tcgtagcgat tttgattcct tttgccatgt
    26221 tctcactcct ttacttttta cacttttatt atcttttttg taaacaaaac aaacaataga
    26281 aattcgtttc tttccagtaa catttacaaa agttagtgtt ttcttctgga tttttgtaaa
    26341 tatcttgtca aaaaatgtct ttattaagct atataacata aatccgttta caaatcattt
    26401 tcaaaaaagt tataatttac gtaaaaaaac aagaagaagg tatctacatg ttattacgtg
    26461 aaaaaatcaa agaaatctcc ttttctcctt cagaaaatga agtgattcag tttctcttaa
    26521 gcgattctcc agcacttggc gaaatgacca tccaagagat tgctgagcga tgttatgtcc
    26581 acccgtccac actcatccgt gtagcaaaaa aaatgggttt tgatggctgg gtcagttttc
    26641 gtaatgcttt tttagctgaa acagcctatc ttgaagggaa ttttcaagac gtagatgcga
    26701 atcttccttt ttccaccaca gacggtatta tgacgatcgc aaataaaatg gcttctttag
    26761 aacagatgac gattcaagat acactttctc tcattcatca tgaccaactg caaaaagcca
    26821 aacaactaat gcttcaagca aaaaaaatcg tgattttcgc cagtaactcg aatactttga
    26881 tttctcaaga tttcatgctg aaaatgaagc gcatcaaaat ggatgtcacg attgtcacca
    26941 cttttggtga atcgttctat gaagcgtaca attgcacgag tgatatgtgc gggattctga
    27001 tttcttatac gggtgaaaac aatgtgatcc ttcgtaccgc agaaatattg aaacaaaatc
    27061 atgtgccaat tttagctttg accagtatcg gtgattcaac gctatcttca atgagtacag
    27121 ccgctttgcg acttacgaca cgcgaacgac tgtattcgaa aattggtaat tttacgatca
    27181 atacatcgat ttgttatctt ctagacgtgt tatatagttg tgtttttgca gaaaattatc
    27241 aacagaattt agtccatcta atttctgtag gacaaaaatt tgataaacgc cctatcagct
    27301 cagccatcat gaaagagcct ttcaattttg aaaataaaga agtggactaa aaagaataat
    27361 taagcctagt ccattctttc acctaaccgt tcaggtcagt gcggtgataa gtgcatcgtc
    27421 tggcccgacc gtctcccctt gattttccaa aatatccaaa taatccgtgt aattggtgac
    27481 gatcacaggt gtttctaaac tgtatccttc ctcttcgatt ttcttcttgt cgaagcggag
    27541 caacagatcg ccttgtttca ctctttctcc ttgctgcacc aagcttttaa aatattttcc
    27601 ttctaactga acagtatcca atccgacatg aatcagcaat tccagacctg cttcagaaac
    27661 cattccgatt gcatgtttcg tcgggaacag ggtcatgact gttccgtcaa aaggggcacg
    27721 tacttctcct ttttcagggt agatcaagat tcctcgacct aatgttcctt gtgcaaaagc
    27781 tgcatccttt gctgcattca gtggagcgat ttgtccttgt atcggtgttt ttacaatttc
    27841 tttacctgat gttttctgtc tatcatctgt ttcatctgct tcctccttcc aaaagaaaaa
    27901 agtcagcgca aaggatacca ccatcgcaat ggcgatccca atcaatacat taatcacatc
    27961 tgttaaatta ccatctggtc taatatagtt gggaattgta aagatgccta gtccaccttg
    28021 attccaagaa gttaaattca ttaacccact atacgcgccc cctaacgcac caccgacaca
    28081 ggtaaaaata aatatttttt tacgtggcaa tgtaaaccca taaatagctg gctctgtaat
    28141 ccccacaata ccagaaacaa tggctggtat tgcaattgct ttgtcttttg gatttctaag
    28201 cttaaagtag agtgcagtaa gtgctgcagt ttgtccaaaa gacactactg caacaggtgt
    28261 catgatattt tgccagccat tcacagaaaa ttgcatcaat cccattggta cgattgccca
    28321 atggagacca aacatcatta gaatttgcca gaagaagcct acgattgctc cataaataac
    28381 tggcgaaagt gctaaaagtg tttcaaatcc agccattaaa atatcagttg cgaatgtgaa
    28441 tgctggtcca acgagtaaaa aacctaaggg cattgtaata agaacggtga agaatggaac
    28501 gaagaaattc gcgatcatct caggtactaa ctttttaatt ggtttctgaa tttggctagc
    28561 taacaacaca ataaagataa tgggaatgac agaagaagcg tagttacgcg caatccaggg
    28621 aatgccgaat actgtttgat aaataggtgc ttcaaaaata gtgccagaaa atatggtcgt
    28681 cagtggtgct tctgctgcac cactcaaagc ttccagcgac aagctaggat tcattaatgc
    28741 tgccccaagc aacatcccta cgaattcatt tactttaaat ttacgggcag ctgttaaacc
    28801 gataataaca ggcataaatt ggaatacaga atcaccgata ttatcaaaca taacaaatgt
    28861 gccagaaccg cggtcaaatg cgcctaagaa gacaagtaat gctgtcagtc cacgaatcat
    28921 cccaccagca gctagaatag caaggaatgg ctggaaacag cccgatattc catcaataag
    28981 catatcaaac ggtctcattt tttctgttga aacagcctca tcaaaagtaa ggtttcctgc
    29041 tcttataacc tcttcaaaca cgactggcac atgattcccg atgacaactt ggtactgtcc
    29101 tcccgctcgc attaccgtca caacaccgtc catatttttc aagatctcat catttgcttt
    29161 ttcttcgttt tttaatttga aacgaagcct tgtgatacaa tgtgtcaaac cattgatatt
    29221 ttccttcccg ccgacatttt ctacaatttt gctcgctaat tcttgatatt ttcccatttc
    29281 tattccctcc aatttattag tggaaggttt agccaactga atgtcactac ccttatttca
    29341 tgcgttcttg ttaatttatc ctcctttttt atttatttac aacgattctc atgcactaaa
    29401 cgcgcagtat ggatcgttaa atacattttt tcgtccgtgg acatctggta gttgaatatc
    29461 tcggctaaaa agtctgctat tttctcaacg caaccaaacg tatccttata ttttttttga
    29521 ataacttggt acaattcctc agaaacttct cccacttctg atttttctcc atctaggacg
    29581 cgtgtcagaa aaaaacgtag gtgtgtgacg aatcgaaaaa aatggactga atcttcatca
    29641 aatgtaatct tatagtaata gcggacgata tttagaatat cctgtattgt tgtagtaaac
    29701 aggtaggtat tgtcttgttg gctttgaatg ccttgtgcat tgactaaatg caatgcgata
    29761 aatccggctt catcttctga taacttgatg tggtatttat ccgagatttt cttcactgtt
    29821 ttttccccga tggcatactc tttaggaaat agttgtttga tatcatacag caatacattt
    29881 ggtacaaata ttcccatttt gtgacgttcg atagccgtat acaaatgatc cgtcaatgca
    29941 atatacactg aatcattcaa ctggacttgt agagcctctt ttgtatattc aatgatttca
    30001 caagaaattt ctaagtactc aagaggaatc gcttgtgcca attcttggaa ctgttctgaa
    30061 agtccgtcat ttgtcaactg aaattttttg tcgatgcatg agtcaaaaat cgggtcaccc
    30121 actttctttt tgaatgccaa accttttccc atcacgatca tttcctgatt tctttcatct
    30181 ctggttatta cgacgttgtt attcagtact ttctcaatca gcatgtttta ctcctttcca
    30241 tgatatatag ggctgtatcc aaaacaaaaa gaaaaaccca aaaagccgtc catggaacca
    30301 tgggagactc atcaggttta gcttgcatca ggcaatcact atccaagttg tatcgttttc
    30361 tttatattat cgaaagcaag cgcttttgtc aacgctttct tagtggctat taggcacttc
    30421 tgactagctg tcgaatcttt tttaaatctg gtgactacga cactaccgct cacagatgaa
    30481 gaatctggga agctctgttt tattttcact ctagcgctta ggtcaaaatg ctactatgct
    30541 actgtcccaa cttctaatat acggtgttcc agtatcagct tatcggtgat aagccaaatt
    30601 tatgcaaaaa tctggaaagc cttttttaca atttttttct tatcacctaa agctgaacgg
    30661 agccctgtca caaccacttt ttacacacca ctgctttgca gtttgtacat atctgcatac
    30721 aaaccatttt gcgctagaag tgtttcatga ttcccgcgtt ctactatatg acctttgtct
    30781 aaaactaaaa tcaattctgc atcccgaatc gtggacagcc gatgggcaat cgcaatcgtt
    30841 gtccgtcctt gtcgcatttt tgtcaatcct tcttggatca atccttctgt ttcagtatcg
    30901 atatttgctg tcgcttcatc caatactagt attttaggat ctgtcacgat tgttcgcgca
    30961 aaagtgatca gctgtcgttg tccgctagaa tagctggcac cgtgttcgat cacttttgag
    31021 tgatatcctt ttggtaattc atcgatgaac ttgtttgctt gaacaaactc agctgcatgg
    31081 cgaatctgtt cgtctgtgat agttggattc atcatccgga tatttcctgc gatatctcca
    31141 taaaacaaga aggcatcttg caagaccaat cccattttct tacgtaactc ttccattgga
    31201 tattctcgaa tgtcatgatc atcaatcaag atctggcctt cataaaattc gtaaaaccgc
    31261 atcaatacgt tgatgatcga gctttttccg cttccggtgt gccccactaa tgcaacggtc
    31321 tctcccggat tagcgacaaa agagatattg ttcaatacat tgtgctctcc atcataagaa
    31381 aagcttacat tgcgaaactc gatcttacct gaagtaatcg tttgatctgc tccaggattt
    31441 tgttgcggtg catatttttc tgtatccatg attttcaaaa tacgactacc ggcaaccatt
    31501 ccatctgtaa aggtgctcaa aaagtccatc atttgagaca ttggattaaa aaatccctgg
    31561 acataggtcg taaatgcata gatcagtcca acttctacgg gagaatgcag cgcatcgatc
    31621 ccaaacaaag tcaacgccaa cgcaatcgcc aatgcatata gaaaattgat gatcggactt
    31681 aacagaatcg aattcgtttt gatcatcgca tagcgcgtgt ctaaatactc gttgttcact
    31741 tgttcaaatt ctttagctaa acgagcttct tggcgaaact gctggataat acgcatgccg
    31801 gaaatcgatt cattcaattt cgtgttcagc tgacttaatt tttcccgcat attccggtaa
    31861 atacgagaac tgaatttctg gtaataccag atgacgattc ctaaaatcgg caagaacacc
    31921 aaagtccaca aggcaatttc tccattgatt tgaaacatgg caatgaagga agaaacgact
    31981 gcaaagatcc cagtcaatac catcaaaaag acataccaaa attcaaatag cgtttctgtg
    32041 tcatttgtca ctcgagaaac ggtcgatcct gccggtgtct gatcaaaata acgcatacct
    32101 agtgtatgca gcttttcaaa taatcttacc cgaacatact gataggtctt caatgaagcc
    32161 atggaataca aataccattg gaaaaaccaa atgatacttt tgactatgac tccaaacaag
    32221 tacataccag caaaaaacaa aataacttgt gtcgtagccg actgtttagc cagatgatca
    32281 tccataaaag tttggatgat ccttggcaat aggacattga tcacagacag agcaaacgca
    32341 aataagatag caacgatgaa cgttcttcta aaaggtttgg cgaacttcat cagtcgtttg
    32401 atgatcttct tctgttcttt aagtggaatc gattttgtcc attccgattg ataattttca
    32461 tccatcaggc ctcgcctcct tctatcttcg cttctaattg ctgtttctcc cacattcgtt
    32521 cataccagcc gcctaatgca agcagctcat gatgggttcc tcgttcaatg attttccctt
    32581 gatcgacaac aatgatttct tttgcatgca tcacgctgct taaacggtga gctgcaatga
    32641 tggttgtttt ctcttttctt atttctttta aattatgcaa gatagcttct tctgttttgg
    32701 catctactgc agaaagtgca tcatctaaga tcagcaattc aggatttttg atcaatgctc
    32761 gagcaatcga aatcctttgt ttctgtccgc cagataaaga gactccacgt tctccaacta
    32821 aggtatcata accttttggc aattccttga tttcattgtt gataaatgct aaagaagccg
    32881 catgctctac ttcttcttct gaaagttttg gattagaaaa acggatatta tctcgaatgg
    32941 tcatcgaaaa caagaagtga tcttgaggca catagccgat tgatcctaat aaagcattca
    33001 atgaatattc tttgatcgaa cgtccgccaa attggatttt tccttgataa tcatcgtatt
    33061 cacgcatcag taatttgatg atcgtcgttt ttcccgcacc agttttccca acaataccta
    33121 atgtttctcc ttcttggatc acaaatttga tttgttctaa tgctggtgat tcttctttcg
    33181 gatagttaaa agaggaaata gctacattca gctcgccttt tgccggggtc tgcactgcac
    33241 ccagttgttc cacgatatgc gtcttttcat gcaaaagttc attgacgcga tcataagaag
    33301 catttcctct ttccaatacg ttgaacaatc gaccaatcgc aaacatcggc caaacaagca
    33361 taccgatata gctaataaat gagaccatct gcccgatcga gatcgtgcct tccaagacat
    33421 actttccacc taaaataatt gttgcaacat aagacagacc gataatcaag gtaatgaatg
    33481 gatcaaataa ggagtctaaa aaattgactc gtttgttttt aataattgca tcttcaatct
    33541 tttcttcaaa atccgcgaga tcttcttttt cttgtccaaa tgttttaatg actttgattc
    33601 cagtaatact ttcttgtgtc ttatcattga tactagaaaa agcttcttgc gaatcacgaa
    33661 aagcatcgtg gagttttgac cccagcactc gtgaagtaac ggctagtaaa ggcagaggaa
    33721 tcagcgcaat cagtgttaag cgccaatcaa taaacaaaat catcgcaatg atcgttgttc
    33781 cgcccgtgat cactgaatct gcaaaggtca agataccagc tcctgctaca ttttggattg
    33841 cattcaaatc attcgttgca tgagccatca aatctccagt ccgatatttt tggtaaaaga
    33901 gattgtccat ttctgtaaaa tgtttgaata gctgctgccg aagttctttc tccaaccgag
    33961 ctgcacttcc ccaaatattc gtccgccaga tataacgaaa aagatattgt aagagagctg
    34021 caaggatcaa taataagatc caccaggaaa tgatctttat tgataaattt ttatcggcaa
    34081 tctcatcaat gatgatccca atcacctttg gaggaactaa ctgtaccaag gccactgcga
    34141 atagggagaa aatcccaatt aaataatgtt tcttttcctg tcgaaaaaac caacctaatt
    34201 ttctaaaaat cgacatttta ctcctccttt gtctttatca agagcatagg attgtctgtg
    34261 cttgtctttt ttgctgaata gtctgaatag tctaacaaat tacgaaataa aaaacggact
    34321 gaaaaaatca gcccgcaaaa agtctttggg tcagaaccta ttttttccct tggttcttca
    34381 tttgctgcat catctggcga attttcttct cagatggttt ttgccccatt gacatcatca
    34441 ttgatcgcaa catgtcctca ttaacgggag gatttttttc taaatagtct ttcatatatt
    34501 tacgcgctag gaaaaagcca cctactgcgc cgattagcaa agcaataata gcaataagta
    34561 cgacaatacc tgttgatacc atataaatct ctcctttcta tttccgaatt gctctcaatg
    34621 atttatttta ctaaagttta ttgaaaaaag aaaggcgtat tctttagttt catgcaaaaa
    34681 atagtggttt ttttagagaa gaacaaaatt tctttcatta accagcaaga cacgccacga
    34741 aaaaaaatta ggcataccga atatttttct ttaatttttt ctttctgagg tgtagaatgt
    34801 aatcgtagat aaataggaaa ggtggttttt tcttgaataa tcaatccaac aaacaatttc
    34861 ataagcatcg acttattgaa catacaaatg gtttatcttt agctgaagta aatggaacag
    34921 tggatgtacc caagggaaaa agttttttta aaacacttct tgcttactct ggaccaggtg
    34981 cattagtagc agtgggttat atggatccag gtaactggtc cacttcgatc actggtggac
    35041 aaaatttcca atatttattg atgtcagtta ttttgatgtc tagtctgatt gctatgcttt
    35101 tacaatatat ggcagcaaaa ttaggaatcg tgacccaaat ggatttggcc caagcaatcc
    35161 gagcacggac aagtaagaca ttgggtgtca ttttatggat cttgactgaa ttagccatta
    35221 tggcaacaga catcgcagaa gtcattggtg cagcaatcgc cctctacctg ctttttgata
    35281 ttccattagt gattgccgta tttatcactg tgttagatgt tttcgtcctc ttattgctga
    35341 caaaagtcgg gtttcgtaaa atcgaagctt tggttgtctg cttgattttc gtcattttat
    35401 tcgttttcgt ctatcaagtt ggcttgtcta accctgattg gcacagtttg tttgccggct
    35461 ttatccctaa cagtcataca ttctcagact caccggtcat cggcggtgaa actccgctga
    35521 ctggagcttt agggattatt ggtgcaacag tcatgccgca taacttatat cttcattcag
    35581 cagtttctca aactcggaag atcgatcacc aagatgaaga agatgtagca caagcggtac
    35641 gcttttctac ttgggattct aatatccagt tgtcaatggc ttttctagtc aatgcactgc
    35701 tattgatcat gggtgtcgct gtattcaaaa ccggttctgt ccaagatcct tccttttttg
    35761 gtctgtatga agctttatct gatccatcag ctatgagcaa tggtatcttg attgctgtcg
    35821 caaaatctgg tatcttgtcc actttatttg ctgtagcact tcttgcttct ggccagaact
    35881 ctactattac tggtacgttg accggtcaag tcatcatgga aggcttcatc catatgcgta
    35941 tcccgatttg gctaagaaga ctagtcacac gattgctttc tgtgattcct gtattgattt
    36001 gtgttttgtt tacaagtaca aaaggaacga tcgaagaaca taccgctttg aataacttga
    36061 tgaatgaatc ccaagttttt ctggcttttg cattgccatt ctcgatgatt cctttactga
    36121 tgatgaccaa tagccaagcg gagatgggga gccgattcaa aaattcattt gttgtaaaac
    36181 tacttggctg gttctctgtg attagtctga cttacttgaa cttacgagga ttaccaggtc
    36241 aaatcgaaag tttcttcggc gagcaagcca cctcagctca actagcattg gctgatcaaa
    36301 tcgcttatgt aatcattgtt cttgtccttc tcctgttggc atggacgatt ggtgatttat
    36361 ataaaggaaa caaaaaatat gaacagcgtt tgcaagaaac gatagaagaa atcgaataga
    36421 aactgattct tttacacaaa ggaggttgtg acagaagtgg gcagcttcaa gaaataagaa
    36481 ggaatttaag aaaattgctt ttcaaatttt tgtgaaattt cggcttattt ttcgaagaag
    36541 ttacttctgg aacaccgtgt atcagaggtt gtgaaaaagc tgtcctgcat caagtaataa
    36601 gaacagccaa acaaaaatag ttcctcatat tttacgtttg gttgagctta ttaccgcaga
    36661 tgcaagcttt tgaacaccgt ttattcggaa aaaggaactg cgacaagact tttgtcacag
    36721 ttcccttttt atttagaaga taaagctttt ttcagattca atttactgaa aactagcatg
    36781 cttgttacta cgatgaattg tgttaatggc acgcctgcgc cagtgtagac acttaaaaaa
    36841 taatcctttt tttctggcgc ataagaacaa aaccacgaga caccgaaaag aaaaaccaat
    36901 tgtgtcagta ttaatccggt gactacaatc aaagaggaac tataataggc acgatcagct
    36961 tttgcaaata cggttcctag tatcataagt aatatccctg ctattgaagc aatcagcacg
    37021 ggaatggcca gaacttggta aatttttatc atgacattcg cgacttttgc tgtttttgtc
    37081 aactggaaat caggtgttct cggatcactg ctatcgatcc aattatccat tagtggaaga
    37141 ttcaataatt cttgggcctg ttcgacttgt tcttgcgtcc cgaaactata attccctcct
    37201 tgatggaaat ctttgtatcg ccatgcatag gcatatcctg atttcagaaa agcaaatacg
    37261 attggcagat cattcatcgt ctttccatcc cctgatccca tcagatagaa ttcttttttc
    37321 tttttgatag ttcccttttg ataggcttct tctaattctt gattgacttt tttccaaaaa
    37381 tcattggttt cttttgcatt gttttggtaa taaccagatt cgcttaccac atctcgcaat
    37441 gcccaaaaaa tgatatctcc tggtaattct tttacttttc cgccttgggt ccacgcatga
    37501 gtcgtataca attcgtcaat acgagtagaa acagtatgaa atgtaggaga tgcgtctaat
    37561 gctttattta atgcagcatg cgagacccat atctcactgt tttctttatt taagttcgtt
    37621 tcgtcatcta ttcggatcag ctgtttcatc aaacgtccaa attcaccact cgaacggtca
    37681 ttgatggtgg caataccata tgttgtctcg tttttatatt cgatccactg atagacgatg
    37741 gagaaaccga ctagagggag taaaaacaat gaaagtttca gccattcttg tttcgaaagg
    37801 agaaatggtc gttcttttaa cttctttgct tctttgaaag aaaagtcttg tcctagcaag
    37861 atctgaacga aactgatgcc taacgcgact acagtaaaag gaagaagcca gatggaatct
    37921 tcgcgaatga accaaaagaa aggaaaagaa acagctaacc ctaaaaacca cggcagcaat
    37981 tttctgcggg aactatattt acggtaataa atagctagta aacaagcgat aatgatctca
    38041 acagccggga tcacgagagc attacgatac gttcgagtgg aatactcatg tgtaaaacta
    38101 atcggagaaa acaaaaaata aaaatagata cttaaaagaa gatacttgtt cttcacgatc
    38161 ggtttaaacg ctagtgcaac caatatgctg gcaagaatac tgaacatgcc gaacaaaact
    38221 gcataagaaa gatgcagttt atgtgcaagt actaaaaaca agctgtagga gatccctttt
    38281 gaaagtgtcg tagtcgtgta ctcccctagc catttaccat ccaaaatatt ttgagcatag
    38341 tgaatcagca gctgatcatc ataggttgcc gacatatctg ttccatagat tgctttacta
    38401 tataaataca accgaataat tgtaaataat acggctatgc caagaataaa gtatgtatgt
    38461 ttctttttta gttggttgat caagggtttt aaagtgttca gcatcttttc gtcctttcaa
    38521 tcacgttttg ctacttgctt gtgaatcttt tcgtttttta cttttctatc agtataccct
    38581 gtttgtctga atttaaaaag agggggcgaa aggagcatgg cgaaaacgac tgcaaaaagc
    38641 actcctttgt ttcttaaaca aaaaaggaca aggcagactg cccaatcctt ttttgttgct
    38701 gtcagataga aaacttaaag tgtgacttct tctgctaata actcaggaaa cacttcggga
    38761 tcgaatgctt gcgctttgaa catggcaatt tcttttccat atggtgcgta agctttcttt
    38821 ttatctttac cgacatatgg agtttctaag attttcgaaa tgttgtcaaa cattggatca
    38881 tggacgattt tgttcaatgt gtcaaatcca attgttccaa aaccgatatt ggcatgccga
    38941 tctttatgag aaccttgtgg atttttagaa tcgttgatat ggagtacttt aagccgatct
    39001 aatccgatga ccttatcaaa ctcttccatc acacctgaga aatcttcttt tatattatat
    39061 ccggcatcat tcgtatgaca tgtatcaaaa gtaacggata atttttcatt caattttact
    39121 ccatcgatga tttgcgctag ttcctcaaat gttcgaccga tttccgtacc tttccctgcc
    39181 atcgtctcca aagcgatctg tgccgtctgt tcttttgtca aaacttcatt caaaccctca
    39241 ataattctag caatcccacc ttctgcccct gctcctacat gagcgcctgg gtgaagggtg
    39301 atttgagtag cacctaaagc ttccgcacga acaatctctt ctctcagaaa ttgtacagca
    39361 aatggaaaca tttctggttt gatcgtattt cccaaattaa tgatataggg cgcatgaacg
    39421 acgatatttg ttagtccgtt ttctgccata aatgcttttc cggcatcaat attcatctct
    39481 tcgatagctt ttcttctagt attttgagga gcgcctgtat agatcataaa ggtcgaagat
    39541 ccgtaactgg ctgcttcttc tgccgcgcct aacagcattt tctttccgct catgctgacg
    39601 tgtgagccta ataacatgga tggattcctc cttgaaaggc aattgtttcg aacaattcct
    39661 atatattggt aagatgatgt acaaagaaaa tggtttgttt ttctttgccc tgttctccat
    39721 agtaactgaa actttctcta aagaaaagct taagaactct ttcataaaaa agatcatttc
    39781 ctcacgtttt atctcattcg aaaaagaaat tcctgtcaaa aacagccttg tctgtttttt
    39841 tgtcttatta tttgctataa ttagcgaaat aaaaccatta gttgaggtga cccttttgcc
    39901 acgcaaaaat actcgaaaaa aacagaatag aagaaaaaaa gaaaaatggt ttgttcctaa
    39961 ggttattttt agagtgtttc aatcattgac tgtttttatt actgttcttc ttttgttgtt
    40021 cgcagctcta ggtatcggaa taggtgctgg ctactttgcc tatcttgtcg aagacacaca
    40081 attgccgact aaaaaagaac tgcagacaga actaggaaac attacggaaa cgtcaaagat
    40141 tgtttatgca gataatacag agatatcaaa aatccagaca gatctgatgc ggacgactat
    40201 ttcatctgat aagatttcgc ctttattgaa aaccgcgatt atcagtacag aagatgaata
    40261 cttcgataaa caccaaggtt atgtccctaa agctgtttta cgagcattag tttcagaagc
    40321 tactggcatc ggctcgtctg gaggatccac tttgacacag caattagtca aacagcagat
    40381 cctaaccgat gaaacaacat tcaaacgtaa agcaaacgag atcgttcttt ctgcacaagt
    40441 agaaaaatac ttttcaaaag atgagatcat tgctacgtat ttgaatgtct cgccatttgg
    40501 tcggaataat aaggggcaaa atattgctgg agtccaggaa gctgcaagag gaatctttgg
    40561 tgtagatgca aaagatgtga ctctgccaca agctgcttat atcgctggtt tgcctcaaag
    40621 ccctatcacg tatagtccct acacgaatac aggcgcgcta aaagaagatc tttctgccgg
    40681 tcttgccaga aaagattttg ttttattcag tatgtaccgt gaaggacaaa ttacgaaaga
    40741 acaatacgaa gaagcgaaag cctatgatct tacaaaagac tttctcccac aacaaatcgc
    40801 ggaacagact gacagagaat tcttgtatta taccgtgatg aacgaagcaa caaggattat
    40861 tgcacaacaa ttggcagaaa aagataatgc tgatatgtca gattcatcgg tcagtgaagc
    40921 ttattatcaa aaagcacagc aaacgatcca aaacaaagga tatacgatcc attcgacgat
    40981 cgataaagat atctatgctg cattgcaaac cggcgtagaa aattacggct atatgttaga
    41041 tgatggtgct ggtagccaag tggagactgg aaatgtattg atggacaata ggactggacg
    41101 tatctatgga ttcgtgggtg gccggaatta cagccagaat caaaataacc acgcctttga
    41161 tacagaacgt caagctggtt catccatcaa accggttctt gtttacggtc ctgcaatcga
    41221 tatgggactt gtcggatcag aatcccgtgt atcagattat gcaacgactt ggcaagaagg
    41281 agaaaatgct ggcgagaaaa tcgtcaatgc gaccaatgaa gggtcgaaca ccttccaaac
    41341 cgtccgtgag tcactggaat ggtccaacaa tatcccagct tatcacttat accaagacgt
    41401 attgaattcg ggtggatcga aacaatatgc ttacgagcac tacttggcga agatgaacta
    41461 cccagcaaat gataattggg gcgttgaatc tgctccttta gggacagtag atgtaacgac
    41521 gcttcaacag acaaatggat tccaggcctt agctaatggt ggcgtctacg aagaaggcta
    41581 tatcattgat tccatcacag ataatgcagg taatgtgatt tataaacatg aaagtaattc
    41641 tgtccgtatt tattccgaag caacggcctc gatcatgaat gacatgatgc gcagtgtgat
    41701 caatgaaaaa atcactacac cattcaaaga tgtcatttca agcttaaacg gaaatctagg
    41761 aaaagcagat tgggtcggaa aaactggttc taccaacgaa tacagagatt catggctgat
    41821 cgtctctact ccgtctatca ctatcagtag ctgggcagga cacgatgaca atactggaat
    41881 ggacagccaa gcaaggatac gttcggctaa ttatcttgcc aatctaatca atcaagctta
    41941 ccaagcaaac cctgagattt tcggcactga tgagaaattt gacttatcat ctgatgtgat
    42001 gaagaaaaaa gtatctgggt tcacaggaca aacagctgga aaagttactg tcaataaaaa
    42061 atctatccaa acgccaggaa aaacagtgga atcactttgg gcaaaaaatg gtccgaagaa
    42121 aagcgccttt aaattcggcg ttggcggtac tgatgaaaac tatacagatt actggaacac
    42181 cgcttcagct tatgctagag cgaatccaga gaccaaagaa tcagacgata aagatgattg
    42241 atctaataga ttaatcagaa ttaaagggag ctgcgacaaa aatcttgtca cagctccctt
    42301 tttccgaata aatggtgttc aaaagcttgc atctacgata ttaagacaaa tttatgtaaa
    42361 aatgtgaaaa gccattttca caaaattttt ctatataact ttactaacga aactgtttta
    42421 atttcttttc ttgtctttgg aataattcgg ttagtttttc tgcaaattgc ccttttactg
    42481 attctttcaa gtgtacatgt cggttagaaa attcttgagc agcttcttct gcagtcattt
    42541 ggtggttttg atctgtcaat cgtttttctg cccaaatttg ctgagatatc cccataccaa
    42601 ctgaacgtac atttgatcga tgtagatttt tctctaattc ttttagtaat tgcattaaaa
    42661 attcattcat aagatgattt ctccatagtt atttgtctga ttttttgacg ataggaacgt
    42721 tctagttcgt cttgctgctg atagagtttt cgtcgttcta cttgtagggc ttgttgataa
    42781 tgctcctgat aattcgaata acttcgtctt gcttgaaaca gaggctcatt atctaaagct
    42841 aagttcttta atacatgatg cagtcgctgc tcctcttgct ccatcaatcg taatccttga
    42901 ttcttaaagt ggatcaattc atcttcttga gcttctaatt gtcttcgttc acttcgataa
    42961 tctctttcca attcttctag tttcatctac ttctccttta attgaattgc tgtgctaatt
    43021 ctcgatctcg tgtcacgatt tcattgattt tgtcttggat ctccttcacc aatgtatcaa
    43081 aggcctcccc catacgtctt gccttattga ttcgcagcag atagacttct ttcgcagaat
    43141 cgactaagtt ctcttttgtg gcgacaacac tagctaatgc ttctatgatt tcctgttcag
    43201 tcaacgaagg ggcgacaaca cgtgcttgcc gcaagccttc ttgccatgcc attttttctc
    43261 tagctcaaaa attcctcttt gattgatgcg gataacttct tccatagcgc ttttcatttt
    43321 tgctgataac ttttccacta ctaacctagc ttgtgtgtca tctaagtaaa tttgttcatt
    43381 aactgtcagc cggccgccac ttaatcgtag ttttttacgt atgttgttca gttcttgcaa
    43441 ctgataggaa aacaactggg tcgcttggtt ttctttctgt tgttttcgag ctttaacatt
    43501 attttcattt tcaggaataa tcagctttcc attttcatca aacttccaag aggttaaact
    43561 gtgggaagca agcagattca agaatgctgt ttccatactg atccgaactt cagcacctgt
    43621 gccattacca ccaaaattac cgataaaatc ggcgtgattt cggtaattgg tgagcatacc
    43681 gggattttct tccacccatt tttttgcttc tggtgataag agatcatacg ggtccggccc
    43741 gtttaagccg acatttttcc attgtttctc tgctgctaca tataatgcta agaatccacc
    43801 taatgaatgg ccggtagtag aaatagcagc ttctccatat tcctttttta cttcattagc
    43861 aaatgcaatc gctgaattga tttgccccgc tgttttcaat ccactaacgg ataaaatctt
    43921 gtttgttgtt gctttttcag aaaaacttgc tcctggtcta ttcccataga gattcatgat
    43981 actccttgca tccgtttcca aatctttcca atcacttaag ttcgttcctg caaaagcaat
    44041 cactacttga gaaagatcca ctttaccgtt cttgattggc gctacaccca tcgcctgcat
    44101 gccgtccaat gagtctttga tttttaggat tttaaaatta taactatcaa tttttttaat
    44161 agaattttct ttataagtat gatcatagtc tctgtgttta ggatctagcc agtaaacagc
    44221 ctcactaata acactgtatt gtttgtctgc catcattaaa tatattcctc cttattatta
    44281 gaaaaaatta ctctgatttt atttactgta atcccctctt tttgtatact tttattttct
    44341 acgccataat ctcctaattc atttcgttct ttccaaaatc caaacgtaaa ataaacagac
    44401 tcatcgtgat tatttatcat tgtcacaaac atacgatatg ctcccgtcat ttcatttcga
    44461 gcagattttt caatcttcac ttccttgata tccgcaaaag tatttttcaa aactttgact
    44521 gactgttttt ctactgcgag taaatctttc tgtctttgtg cttctctttt gtccatatag
    44581 actttccctc cgattcctaa tatgacgatt aataaaatgg ctaagctgag ttttcttatt
    44641 ttccgagaca agaacgtgcc tcctttcttt ttatgtaagt attgatacct tcattattta
    44701 agtacgcgaa agtttgtagg aattttttta tttttgaaat ttttctccaa tttgctatgg
    44761 acgattggcg ctgcagccat cgcctgcatg ccatccaatg agtctttgat ttttaggatt
    44821 tggaattttg tttctccaaa gtttttaatg gcgccttctt tgtaactttt actatattga
    44881 ggatgttttg gatctagcca ataaacatgt tcacttatat atctatactc ttcgtctttt
    44941 actgtcacac ttcctccgcc tctccattag aataaataac tcttatttta ggagtagtaa
    45001 ccccttcgtt ttgtatttct tcattttcta caccataact gctaatttca ttcatttgtt
    45061 ttgaaaaaaa ataatcaaaa taaacagatt tcccttcatt atttgtcatt gtcacaagtg
    45121 caccataaca tccagtaaca gggttttttt taaattcttc taccttcact tccctgatat
    45181 ctgcaaaggt atttttcaga actttgacgg attgtttttc tactgcgagt aaatctttct
    45241 gtctttgtgc ttctcttttg tccatgtaaa attttcctcc gattcctata gcaagaatgg
    45301 tcaaaatgat gactatggtc tttcgtcttt tcttaggcaa atagaagtct cctttcgggt
    45361 tatgtatgat ggattgtttc tcctttaaga taagtacgca atcgagcctg gatttttttg
    45421 gattttttag agttactttt ctacttttct actttctttt ttatcacgtt ttcattttaa
    45481 agtaattttg atagtagtga acaaaatgta gcatctacgc acagattgtg tcgtatacga
    45541 tggacgtaag gtttgtttcc gccattttct ctttttttaa agtcacaaaa aaaaggggtt
    45601 atgacaaaat tttgtcataa ccccttttct cgaataaacg ttgttccaga agttggccac
    45661 ttttggaaca acctctaaat gattgatctt ttattattta gttgatcctt tttcttcgat
    45721 tccataaggc aagataatcg ttttttcttc gacttcttct ttattcatca ttttcgtcaa
    45781 taggcgcatg gataccgctc ctaaatcgta taatggttgt gtgatacttg tcaaacgagg
    45841 acgagctact tctgtcagta aagaattgtt gcttgtgatg atttcgaatt cttctggtac
    45901 ttttacgcca cggtctaata aaccatccaa gataccaatg gctaattcat cgtctgaaac
    45961 atagacagct gttgcaccgc tattatggat ccggtcaact agagacagac catctttaaa
    46021 gttgtattgt gcctcaaaga ttaatccttc gctatatggt agattgtttt cgcttaatgc
    46081 ttctttatag ccttttagac ggttttgacc attgatagga tcaatcagcg caccgctgac
    46141 aaaagcaatt tttttattgc cgctttttgc taatttattt actgcatctt ttgttgctga
    46201 tacataatca atgtttacgc tacctacttg ttcatctgga tcaatggaac cagctagtac
    46261 aacaggtgtt tttgaacgtg aaaattctcc acggatttcg tctgtgatat ggtgacccat
    46321 aaagatcacg ccgtccactt gcttagccaa taaattattc aatacattga cttctttttg
    46381 atcgttgcca tctgagtttg ctaagatgat attgtatttg tacattgttg ctacatcgtc
    46441 gataccacgt gctaaagagg caaagaacat attgctgaca tcaggaatga ttaccccaac
    46501 agttgttgtt ttcttacttg ccaagccacg tgcgactgca tttggacgat aatccaagcg
    46561 atcgataact tccaagactt tttttcttgt tgctggtttg acgtttggat tgccatttac
    46621 gacacgtgaa acagtagcca tcgaaacatt tgcctctctc gctacatcat agatagtgat
    46681 tgtttgcttt tccatttgtg ttctcctatt catattttat atgttttctg aaaatacgtc
    46741 ttacatttct aaaataggat atcaaataat ctcaacaatt gcaaccgttt tatctctgtt
    46801 ttcatgaaaa tttttacttt tttcagtttt aagaacgttg gtcttttaat caatcagtgg
    46861 tacaattatt gaatacaaaa ttaatttaga aagtaggttg ccaaatgaat aacgtaaaaa
    46921 tcaatgaact acgtcaatgg atggcacaac accaagtaga attggcttat atcagcgacc
    46981 ctggccacat cgcttacttt tccggatatg aaagtgatcc tcacgagcgt gtactagctc
    47041 tttttatccc tcttgaacaa gatcctttcc ttttcactcc tgctctggaa gttgaagatg
    47101 ctcaaaacag cagctgggcg tacgatgtac gtggctactt agacagcgaa aacccttggg
    47161 agatcatcgg aaaagagctt cgcgcacgct atgggcaacc tggtaatgta gggattgaaa
    47221 agaatgctct gactgtcgat cgcttcgatg ctatctctga tatcttgaca ggtgcagatt
    47281 cttacactga tctaacttct attatccagc gtctgcaact gatcaagacg gtagaagaaa
    47341 aagacaaact gatcgaagct ggtaaatggg ccgatgttgc ctttgaaatt ggcttcaaaa
    47401 cagtaaaaga aggcgtgact gaacaagcaa ttatcgcaga aatcgaatac caattaaaaa
    47461 aacaaggtgt ttcacaaatg tctttcgaca ccttagtcct tgcaggagca aatgctgcaa
    47521 gccctcatgg tacaccagga agcacgaagg tttcaccaaa tgaactagtg ttattcgatc
    47581 ttggcgttgt ttggaatggc tattgcagtg atgctactcg tacagttgct tatcaaaaac
    47641 caacagaatt ccaagaaaaa atctacaaca tcactcttga agcacagctt gccgcacaag
    47701 aggcagttcg cccaggtgtg acagcaggtg aacttgatca aatcgcacga aacgtaatca
    47761 acagctatgg ctacggcgaa tatttcaatc accgtttagg tcacggaatt gggacaaccg
    47821 tccacgaatt cccttctctt gtagaaggaa acgacttagt gatcgaagaa gggatgtgct
    47881 tctctcttga accaggaatc tatattcctg aaaaagtagg ggtacgtatc gaagattgtg
    47941 tgtatgtgac aagtgatggt tgtgtgccat tcacgactac accaaaagaa ttacttgttt
    48001 tagagtaatg aaaataaaaa aggtgggagc tggtccgctc tcaccttttt attctagaaa
    48061 tgagtattct tagtgattgg tagtcgaatc tgtcattgta tctttcattt cttttttagc
    48121 ttcttttgca tcttcttttg ccattttcaa catttctttt gtgtcatctg caactggttt
    48181 tgcttctgac attccttcat tgaccgtctc tcctgcttta tctgcagcat cttttacatc
    48241 gatcatgata tcttctgaag tatctttagc aatactacct aattcgtctg ctggtttttt
    48301 cagatcttct gctgtttttt tgaaacgatt agataaatca gctgattgtt ctttgaggtt
    48361 taacaagata tcatctgatt cacttcctgc ttcctctgct gattcactta ccttttgctt
    48421 aacattacct gctagatccc ctgcttgttg agaaagatct tgcgcttttt cttttgcaat
    48481 gcctgttaac tcagctgatt tttcttttgc catatctgtg taatctgaag ccatgtccat
    48541 caaatcatct gcttgagcag ccaattcatc ccgaagttct ttaccagatt tgggtgctaa
    48601 caataatgcg gcgattgctg cggctgtacc tccaactact gcacctaata aaaatccacc
    48661 ttttttagcc attcttattt tcctcctgtc gtttcagtat gttttttgtt tttaaaaaat
    48721 ttcatcgctg ttccaccgac ttttccggca acagtcgctt tagctgtcgt ttttccgatt
    48781 ccgccgactt tcgtcacgat gtttttacta gaatgattaa gttccgatac actttcactt
    48841 aaatcagcaa ctgctgtgaa caatggatcg atcgttgcga cttttccatt gatatccaag
    48901 agcagctcat tacttttgac cagcaagcct tctacttgtc tagataaaag atctacgtct
    48961 tttgtgacga tctcaattgt cgtatttgct tctgcgacag tctggtctac tttttctaaa
    49021 gttttggaaa cttgcaacaa tacgcgaatg atgaaaacga caagtatcgc aaaggcgatt
    49081 gctgcgatca atcctgcaat ttctcctcct gacatgatca aactcccttc ttgtctctct
    49141 tttctataag gatagcattt tcgtgttttt taaacaaata aaaacgagct tcaactactt
    49201 tttattcaat tagcagctga agctcgttag aaaaaaatga ttattttttc ttttcttctt
    49261 tgatttctgt tattcctttt ggattatgat cgatcttgct tccttctgct tctaatgttt
    49321 tacctaaaga catgatgtat tcacgcaaag gtgcccctac ttctggatgt gtcagaccat
    49381 attcaatact tgttttcata aaaccaaatt tgtcaccaac gtcataacgt ttacctgtga
    49441 atttacgggc aaatacgcgt tgtgttttat tcaacgtatc gattgcgtca gttagttgga
    49501 tctcatttcc agcacctggt tgttgttctg ataatacatc aaagatttct ggagtcaata
    49561 agtaacgccc aataatagct aaatcacttg gtgctttgct tggatctggt ttttcaacaa
    49621 agtttttgac attgtataac ccatcttcca gtacttcccc tgggttgata attccgtatt
    49681 ttgaagtttc atcgtgagga acttgcataa cggcaatcgt agaagcgtgt gtacgttcat
    49741 agtcatcgat caattgctgt gtcaatggta cttcgtcttc catgatatca tcgcctagca
    49801 taacgacaaa cggttcattt ccaataaagg ctcttgcttg aagaacggcg tgtcctaacc
    49861 cctttggatg agattgacgg atgaaatgca agttgacatc tgtcgtttct tctactaatt
    49921 tcaataattc gatttttcct ttttcactta ggtttgtttc taattcgata tttgaatcaa
    49981 agtgatcttc gattggtcgt ttagcttttc ctgtaacgat caagatgtct tcgattcctg
    50041 atttcaacgc ttcttcaacg atgaattgga tcgttggttt gtccacgatt ggcaacattt
    50101 cctttgccat cgcctttgtt gctggtaaaa atcttgttcc taatcctgct gctggaataa
    50161 ctgctttttt tactttcata tacattcgct ccttcaaaaa attgttaatg agaattcatt
    50221 ttcttttttc ccatcacgta acatgatttc ttttgcggct gttttgattt ctttttgttc
    50281 atacagcact tcatagattg tttgagtgat gggcatttcg atttccatca tttgggctag
    50341 ttccatcgct gcttgagtag tattcacacc ttcaacgacc attcccatat tggctagcac
    50401 ctcttctaga ggctgtcctt gtcctaacaa gttgcctgcg cgccagtttc tggaatgaac
    50461 acttgtgcaa gtaacgacta gatcgcctac tccgcttaag ccaataaagg tcagcgggtt
    50521 ggcacccatt gctacaccta aacggctgat ctcagctaat ccgcgcgtca tgattgccgc
    50581 ttttgcatta tcgccaaacc ctaagccgtg aatagcacca gctccaatgg caataatatt
    50641 tttcaaagct gcccccatct ctacaccaac cacatcaggg ttagtataga ttcgaaaata
    50701 atggttcatg aacagctctt gtacatattt tgctgctttt gcatctgtgc ttgccgctgt
    50761 gatcgtcgta atgtcatgct ttgctacttc ttccgcatgg cttggcccag aaagaacagc
    50821 aacagctttt cttttttctg tcgggatttc ctctaacaag atttcagaga ttcttttatg
    50881 cgttccctgt tctaatccct tacttgcgtg gatgatcact ggcttcgtat tcaatttggc
    50941 aactagttct tttgcaacag aacgtatcgc tttcgtcggg ataacgaata gtaccgcatc
    51001 tgcatctttt actgcatctt ccatatcggt gaatgctcgg atggaatcgg gtagatgatg
    51061 atctggtaaa taacgttgat tggtgtgttg ggtgttgatt tcttctactt gtgaagcacg
    51121 atgtccccaa atccgaacgt catgtccgtt ttcagcgagg acttgtgcta aagcagtccc
    51181 ccaagagcct ggtcctaaaa ccgctactct ataattcatt ttaccactcc tgaaattttt
    51241 ttcattttta acgctctaaa aatcaaataa tttgttgatt ttttcctaat gagcggtcat
    51301 aatccggtaa atttcctttt tttctacgcc aaataaacag aatcaatgtg ccgacaagta
    51361 aaacagcaga caataattga gaaatgcgga tcacacctaa aaagtaaagg ctgtctgtgc
    51421 gtaatccttc gataaagaaa cgtccgaaac tataccacat tagataacat aaaaggactt
    51481 ctcctttttt caaaagatgc ggtttcttcc gcaaaaccaa aagcagaata aatccaatca
    51541 aactccaaag tgattcataa agaaaggttg gttgtcgata gatcccttcg atatacatgt
    51601 tatcaatgat gaattgcggt aaatgcagac tttctaagaa acttcgtgtc gtgtctggac
    51661 catacgcttc gtggttcatg aaatttcccc atcgtccgat tgcctgcgcc agtaatacac
    51721 ttggtgcagc gatatctaaa aaggtccaca aagaaataaa atgatatttg gtaaaaaagt
    51781 acagtgtgat tgcacctgca atcaatcccc cgtaaatcgc taatcctcct gaacggatat
    51841 tgaatatttg gattggatca gctatatatt ggggaagatc gaataaaaca taatacaaac
    51901 gggcaccaat aatggaaatc ggcaatcccc acaacataaa atctgtcacg tcatctgctt
    51961 ttaatcctac ccgaacagct tctctgctgc tgagccacat ggcaataatg attcctgata
    52021 cgataatcaa tgcataccag tagataggaa ttcctacaag ctcaaaagca actcgattga
    52081 tttgtgctaa catattgtca ctccttgcta gtcattgcct gagttttctt caatcaagcg
    52141 acttaatctt tcttcaaatg ttttcgttgc gtcaaagccc attgtacgcg cgcggaaatt
    52201 catcgcggct acttcaatga tgattgcaac gtttcgtcct gttttgacag ggatttttat
    52261 ttgtggaatg cccacttccg cgatttcaac ggtcgtgtct tcagaaccca aacggtcgta
    52321 tttcttatct ttcgcccatg cttctagata aacagctaac tggacttgca tagagcctcg
    52381 taccgcactc gcaccgaaaa gattcattac atctatgatc ccgatccctc gaatctcaat
    52441 cagatgttcc aggattttag gaggttctcc gattaccgtc agttcatctt gctgatagac
    52501 atctactcga tcgtctgcga tcaatcgatg tccgcgctta atcagttcca acgccgtttc
    52561 acttttccct atcccactgt ccccttgaat tagtacacct aatccgtaga catcgactaa
    52621 cacaccgtgg acacttgttc gaggggctaa gcgcccatct aaataactag ataattcacc
    52681 tagcagccga gacgttgaga taggcgaacg cagcacagct atcccatttt cattggctgc
    52741 ttggatcatt tcttccggag ccggcaatcc tcttgaaata ataaatgcgg gcatatcttc
    52801 actacataat cttctcatga tgatcaaacg ctcttctggg atcatccgtt ccgcaaaact
    52861 gatttcttta ctgccaaata gctgtaaacg attatgagaa taataattaa aataaccggt
    52921 caactctagt cctgggcgtg agatgtcccc agtcacgatg acgcggtcta aacttttctc
    52981 gtcgcctgtg acgatttcca aagataattt ttttactaat tggctaactt ttacaacttc
    53041 tgacattcat gctacctcat ttctattaga gtgttctcta ccattttatc attgtctagc
    53101 caaaagtact accaattaaa aaaaacgttt ttatttaatt accaatgtaa tagaaaacgc
    53161 attcttaatt atatatgatt tgtcaaatta agctagaata aaatgcttct tgtacatagc
    53221 tcaaaaatat ttcgattggt gttctgtaat tcaatgattt tcttggaata taattacgtt
    53281 gattgctgac actggaaata aatgtctgat tcacttctct aaaatccatt gatttcggca
    53341 gtccattacg acgcagaatc ccgttagaat t
//
LOCUS       DAFEKH010000017        52629 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.018, whole genome shotgun sequence.
ACCESSION   DAFEKH010000017
VERSION     DAFEKH010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 52629)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52629)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52629
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.018"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            85..972
                     /locus_tag="LP386_001079"
     CDS             85..972
                     /locus_tag="LP386_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBL1918330.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTITSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1112..2038
                     /gene="cysK"
                     /locus_tag="LP386_001080"
     CDS             1112..2038
                     /gene="cysK"
                     /locus_tag="LP386_001080"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HBL1918331.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2274..2720
                     /locus_tag="LP386_001081"
     CDS             2274..2720
                     /locus_tag="LP386_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBL1918332.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2993..4345
                     /locus_tag="LP386_001082"
     CDS             2993..4345
                     /locus_tag="LP386_001082"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HBL1918333.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4516..4803
                     /locus_tag="LP386_001083"
     CDS             4516..4803
                     /locus_tag="LP386_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918334.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            5029..5472
                     /locus_tag="LP386_001084"
     CDS             5029..5472
                     /locus_tag="LP386_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL1918335.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(5478..6662)
                     /locus_tag="LP386_001085"
     CDS             complement(5478..6662)
                     /locus_tag="LP386_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HBL1918336.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            6930..7628
                     /locus_tag="LP386_001086"
     CDS             6930..7628
                     /locus_tag="LP386_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBL1918337.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            7635..8312
                     /gene="nth"
                     /locus_tag="LP386_001087"
     CDS             7635..8312
                     /gene="nth"
                     /locus_tag="LP386_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HBL1918338.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(8438..8971)
                     /locus_tag="LP386_001088"
     CDS             complement(8438..8971)
                     /locus_tag="LP386_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918339.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(9268..11649)
                     /locus_tag="LP386_001089"
     CDS             complement(9268..11649)
                     /locus_tag="LP386_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBL1918340.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(11639..12286)
                     /gene="recU"
                     /locus_tag="LP386_001090"
     CDS             complement(11639..12286)
                     /gene="recU"
                     /locus_tag="LP386_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HBL1918341.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            12350..12889
                     /locus_tag="LP386_001091"
     CDS             12350..12889
                     /locus_tag="LP386_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HBL1918342.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            12979..13398
                     /gene="gpsB"
                     /locus_tag="LP386_001092"
     CDS             12979..13398
                     /gene="gpsB"
                     /locus_tag="LP386_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HBL1918343.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            13420..13787
                     /gene="rnpB"
                     /locus_tag="LP386_001093"
     ncRNA           13420..13787
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="LP386_001093"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            13996..15162
                     /locus_tag="LP386_001094"
     CDS             13996..15162
                     /locus_tag="LP386_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HBL1918344.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            15208..16704
                     /locus_tag="LP386_001095"
     CDS             15208..16704
                     /locus_tag="LP386_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HBL1918345.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            16785..17468
                     /locus_tag="LP386_001096"
     CDS             16785..17468
                     /locus_tag="LP386_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBL1918346.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            18113..19303
                     /locus_tag="LP386_001097"
     CDS             18113..19303
                     /locus_tag="LP386_001097"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HBL1918347.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            19405..20358
                     /locus_tag="LP386_001098"
     CDS             19405..20358
                     /locus_tag="LP386_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HBL1918348.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            20427..21776
                     /locus_tag="LP386_001099"
     CDS             20427..21776
                     /locus_tag="LP386_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1918349.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(21959..22282)
                     /locus_tag="LP386_001100"
     CDS             complement(21959..22282)
                     /locus_tag="LP386_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918350.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            22411..23574
                     /locus_tag="LP386_001101"
     CDS             22411..23574
                     /locus_tag="LP386_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBL1918351.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            23644..24993
                     /locus_tag="LP386_001102"
     CDS             23644..24993
                     /locus_tag="LP386_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBL1918352.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(25038..25469)
                     /locus_tag="LP386_001103"
     CDS             complement(25038..25469)
                     /locus_tag="LP386_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1918353.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            25857..28499
                     /gene="alaS"
                     /locus_tag="LP386_001104"
     CDS             25857..28499
                     /gene="alaS"
                     /locus_tag="LP386_001104"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HBL1918354.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            28699..29295
                     /locus_tag="LP386_001105"
     CDS             28699..29295
                     /locus_tag="LP386_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBL1918355.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            29417..30565
                     /locus_tag="LP386_001106"
     CDS             29417..30565
                     /locus_tag="LP386_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBL1918356.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(30603..31016)
                     /locus_tag="LP386_001107"
     CDS             complement(30603..31016)
                     /locus_tag="LP386_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HBL1918357.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            31095..31526
                     /locus_tag="LP386_001108"
     CDS             31095..31526
                     /locus_tag="LP386_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HBL1918358.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(31625..31858)
                     /locus_tag="LP386_001109"
     CDS             complement(31625..31858)
                     /locus_tag="LP386_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HBL1918359.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            32041..33711
                     /locus_tag="LP386_001110"
     CDS             32041..33711
                     /locus_tag="LP386_001110"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HBL1918360.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            33858..34244
                     /locus_tag="LP386_001111"
     CDS             33858..34244
                     /locus_tag="LP386_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918361.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            34231..34929
                     /locus_tag="LP386_001112"
     CDS             34231..34929
                     /locus_tag="LP386_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBL1918362.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            34934..35398
                     /locus_tag="LP386_001113"
     CDS             34934..35398
                     /locus_tag="LP386_001113"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBL1918363.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            35395..36306
                     /locus_tag="LP386_001114"
     CDS             35395..36306
                     /locus_tag="LP386_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBL1918364.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            36541..37080
                     /gene="pyrR"
                     /locus_tag="LP386_001115"
     CDS             36541..37080
                     /gene="pyrR"
                     /locus_tag="LP386_001115"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HBL1918365.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            37094..38377
                     /locus_tag="LP386_001116"
     CDS             37094..38377
                     /locus_tag="LP386_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HBL1918366.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            38390..39316
                     /locus_tag="LP386_001117"
     CDS             38390..39316
                     /locus_tag="LP386_001117"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HBL1918367.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            39335..40615
                     /locus_tag="LP386_001118"
     CDS             39335..40615
                     /locus_tag="LP386_001118"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HBL1918368.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            40620..41696
                     /gene="carA"
                     /locus_tag="LP386_001119"
     CDS             40620..41696
                     /gene="carA"
                     /locus_tag="LP386_001119"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBL1918369.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            41701..44886
                     /gene="carB"
                     /locus_tag="LP386_001120"
     CDS             41701..44886
                     /gene="carB"
                     /locus_tag="LP386_001120"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBL1918370.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVYVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            44940..45716
                     /locus_tag="LP386_001121"
     CDS             44940..45716
                     /locus_tag="LP386_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HBL1918371.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            45713..46645
                     /locus_tag="LP386_001122"
     CDS             45713..46645
                     /locus_tag="LP386_001122"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBL1918372.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            46642..47358
                     /gene="pyrF"
                     /locus_tag="LP386_001123"
     CDS             46642..47358
                     /gene="pyrF"
                     /locus_tag="LP386_001123"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HBL1918373.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            47365..47994
                     /locus_tag="LP386_001124"
     CDS             47365..47994
                     /locus_tag="LP386_001124"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HBL1918374.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            47982..48296
                     /locus_tag="LP386_001125"
     CDS             47982..48296
                     /locus_tag="LP386_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918375.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            48334..48975
                     /locus_tag="LP386_001126"
     CDS             48334..48975
                     /locus_tag="LP386_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBL1918376.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            49018..49710
                     /locus_tag="LP386_001127"
     CDS             49018..49710
                     /locus_tag="LP386_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HBL1918377.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            49707..50609
                     /locus_tag="LP386_001128"
     CDS             49707..50609
                     /locus_tag="LP386_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL1918378.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(50767..52473)
                     /gene="efbA"
                     /locus_tag="LP386_001129"
     CDS             complement(50767..52473)
                     /gene="efbA"
                     /locus_tag="LP386_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HBL1918379.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
BASE COUNT        17219 a         9160 c        11300 g        14950 t
ORIGIN      
        1 aattaaaagt ataatttaat taattaagtt tgttttaaga agagaacttt ttattaagtt
       61 tttttatttt gaggaggaat ttgaatgcaa gagctgaaga cccgcagtgc ccggcaccat
      121 agacctaaaa gaaaaatggt gatcaataaa aaagcgattg ctcctttaat tggaacgagt
      181 cttttagttg ggccgatgat ggttacagcg gtaccgcaac atgttcatgc agatgaacaa
      241 ggatctcaaa cagtcgctga tcctcaagcg tttatcgatc aaatcggctg gtctgcgtca
      301 gaagttgctg caagtaatga cttgtatgct tcagtcatga tcgctcaagc gttgttggaa
      361 agtgcatatg gcacttccgg attagctagt gcgccaaatt ataatctatt cggtgtgaaa
      421 ggaagctata acggacaggt cgtttatatg gcaaccaaag aatatgtaaa cggacaatgg
      481 gtaacgatga atgagccatt ccgaaaatat tcttcttatt gggaatcctt ccaagaccat
      541 gcgaatgttc ttcgttcaac cagtttttcc acgggcgatt atcattatgc tggcgtgtgg
      601 aaaagcaata caacaagttt ttatgatgca acagcgtact tgacaggtcg ttatgctacc
      661 gatccaaatt atggggccaa attgaactca ttgattaata cttataattt aacccgtttt
      721 gatacgccat caacaggttc ggctacaaca atcacaagta caacaacaac gactactacg
      781 acgacttcaa cgtcatcatc ttcaacaaca gatgtaaata caaataatgg tcagacatat
      841 acagtcgtgt caggtgatac gctatgggat attgcacaaa aatttggcat gtctgttgat
      901 gatctaatgg cgaaaaatgg catgtctatg tccagttatt ctttattagt tggtcaagaa
      961 ctaaacgttt gatttagata aaaaggcaaa gaaattacca tatatggtat atctttgtct
     1021 tttttttgct agtcaaagac gaatcactcg ccataaatga acagattgta ttatgataag
     1081 taagaagagc aaagacaagg aggaattgaa gatgacagct atctataact cagtcaccga
     1141 attgattggc aaaacgccaa tcgtcaaatt aaataaaatc gtaccagaag attcagcaga
     1201 tgtttttgta aagcttgagt tttttaatcc aggaggaagt gtaaaagatc gtattgcttt
     1261 aagtatgata gaaaaagcag aacacgatgg tctactgaaa ccaggtgata ctatcattga
     1321 acctacttct ggaaatacag gaatcggatt gtcgatggta ggagttgcaa aaggatataa
     1381 agtaatcatc gtgatgcctg agacgatgag tatcgaaaga cgtttattga tgaaagggta
     1441 cggcgcagag ttgattttga ctcctggtgc ggatggtatt tctggatcaa tcagagaagc
     1501 agaacgtttg gcaaaagaaa acggctactt tttaccatta caatttgaaa atgaagcaaa
     1561 tcctcttgtg catgagaaga cgactggtcc tgagatacat caagcatttg gagtaaatgg
     1621 cttggacgcg tttgttgcag gtatcggtac aggaggaacg atcactggcg ctggccgaga
     1681 attaaaacgt gtgtatccga aaatcgaatt aatcggggta gaaccagcag aatctgctat
     1741 tttagaaggg aaagaagcgg gacctcacaa aatccaagga atcggtacag gttttgttcc
     1801 taaaacactg gatacttctg tgtatgataa agtcctttct attagtggag acgaagcgat
     1861 ggaaacagct agagaagttg ggcgaaaaga agggatttta gtaggcatct catctggcgc
     1921 tgcaattgct gccgcgctaa aagtcgcaaa agaattagga aaaggcaaga aggtattagc
     1981 tgtggttccc gacaatggtg aacgttattt atctacagcc ctttaccaag agatataagg
     2041 cacttggttt ttctccagat aggtttatgt aaaaaacttt taaagatgaa aagaacacac
     2101 aaaaatttat gatgagaaaa attatttgaa tagagacgta gaatagtgaa cgcgactgtt
     2161 ttacgtcttt tttcattaaa atacaataaa attgaatttt cttttcatgt taagtggatt
     2221 ttaaaatgta aaaatagtat gataagacga gaataacaac gtggggtgtt tacatggaaa
     2281 ataagttagt cgaagaggtt atcgaaaagt taaaaaaaga gaacattcga atcacacctc
     2341 aacggtacgc ggttttagaa tatttgattg aacatcattc ccatccaacg gctgatgaga
     2401 tttataaagc acttgaacat cggtttccaa atatgagtgt tgcgactgtt tacaataacc
     2461 ttcgcttatt tacttcgatt ggatttgttc aagaaatgaa gtacggcgat gcttctagcc
     2521 gatttgattt cagttcaaag cgtcattatc atgtaatttg tgaaaactgc ggtaagattg
     2581 ttgattttca ttacccaggg cttgaagata tagaaatggc tgcaagcaga ctgactgatt
     2641 ttgagattaa tgaacatcgg ttggaattgt atggactctg tccggattgt aaagagtcag
     2701 caaaaaaggc gcaaatgtaa aaacagtttc tacaagtgtt atacctaaaa aaagctagct
     2761 gtgtaaaaaa aacgctagct tttttatttt tttgtctttt attcacaatc ttagatataa
     2821 aagtgaatat tattaaaata agaatcttgt agatattggg ttcttatgct tgaaaaggaa
     2881 tgaaactaca aacaaacctt tgtgaattca caagcattaa actgttgtat ccgttttatt
     2941 tctgttatag tagttttgtc gaaggacaaa atgttaatcg gagggaccat aaatgaaagt
     3001 agtagtaatt ggctgtactc atgcaggtac tgcagctgta aaaagtattt taaaaaatca
     3061 tccagaagca gaagtgacag tatatgaaag aaatgacaat atttctttct tatcttgcgg
     3121 tatcgcactt tatgtcggcg gagtagtaaa ggacccagca ggcttgttct actcaaatcc
     3181 tgaagaatta tcttcattag gagcaacagt taaaatggaa cacgatgtaa cagacgtcga
     3241 tacagaaaat aaaacagtaa cggcaaaaga tctgaaaaca ggagaaacag aaacggtttc
     3301 ttatgataaa ttagtgatga caactggttc atggcctatt atcccaccga ttagtggaat
     3361 cgatgcgaaa aatgtactcc tatgcaaaaa ctacaatcaa gcaaatgaaa ttattgcaca
     3421 agcgaaagaa gcaaaacgtg tagtaattgt tggtggtgga tatatcggta ttgaattagt
     3481 agaagctttt gtcgaatctg gaaaacaagt gacattgatt gatggattag atcgcatctt
     3541 gaataaatat ctagataaac cattcacaga tatcttagaa aaagaattga cagaccgcgg
     3601 tgttactctt gcgctaggcg aaaatgttac tgaatttatc acagatgaag aaggaaaagt
     3661 gaaacaagta gctacaccaa cagatacatt tgatacagat atggtcattt tatgtgtggg
     3721 cttccgtcca aatacaaaac tgatcgaagg aaaagtagat acactgccaa acggggcaat
     3781 caaagtgaat gaatacatgc agacaagtaa tccagacatt tttgcagctg gagactctgc
     3841 agtagtcaac tacaatccaa gtggcacgca aaactatatt cctttggcaa caaatgccgt
     3901 tcgtcaaggt ttgcttgtgg gaaataactt gacagatcat aaaatggcgt atcgtggtac
     3961 tcaaggaact tcaggacttt acctatttgg ctggacgatc ggttcgacag gtgtgaccaa
     4021 agaaagcgca actttgaacg atctagaagt ccaagcgact gtatttgaag ataattatcg
     4081 tccagagttc atgccaacta ctgaaaaagt aatgatggag ctagtctatg aaaaaggaac
     4141 gaatcgtatc gtaggtgctc agttcatgtc caaatacgac attacacaat cagcaaatac
     4201 catgtcttta gctgttcaaa ataaaatgac tgtagaagat ctcgcacttt cagatttctt
     4261 cttccaacca cattttgacc gcccatggaa ttacttgaac ctacttgcac aagcagcgct
     4321 aggcgaaatc gaaactgcac aataaagaaa aagggttgtg acacaatttt gtcacgaccc
     4381 tctgtctttt tttgtgaaaa gtacaattag ttgtctttct tcgaattttt tgtcacaata
     4441 agcagcaaag ataaagctgt tacataaaag aacaagcagc tttatttgat tttgaaaaga
     4501 aaggtgagaa agaagatgaa taaagaatat tttgtccaac aagatgcatt tttagaagat
     4561 tataaaagtg cttcgaagaa attaacgatc aatattgatg agttggcaga tcaagtactc
     4621 tctcagttga atgaaacgca agaggaatat tacacgatgc cagcaaatga cgccaaagat
     4681 aatgtttctc atcgttttcc tttcagtaga cgcatctact cagatgaaaa tgacggcaca
     4741 ttgaatacag agtacacata tgaaggtcag ccatatgtgc tagaaactga tgatgatctt
     4801 taaagacagt ttttgaaaag gccgctcatc cttaagtgat gacaaaaaat catcacaatt
     4861 accgatgact gtctctttac tatcttttaa tcagaaaaag gggttatgac aagctttgtc
     4921 aacccctttt tttcttggtt tcagattggg ttttcctaca aaatattttt atctttgttg
     4981 aataggaaac aaaaaaacaa tataatgaaa gaaaaagaag gtgtagaaat ggataaaaga
     5041 caactgctaa tagaagaata tctggattta gctaatgaga ttattcatcg taataaacca
     5101 gaaatggaaa aagaatttgc aggatttact ctaaatgaac tagaagtgat tgaacatatc
     5161 gggaaaatcc ctgatcctaa cgtgacaaaa ttagcgaatg ctagttacat gactagagga
     5221 gccatcagta agctaacaaa aaaactgata gctagaggga tcataaacac ttatcaaagc
     5281 gaagagaata aaaaagaaat ctattttcaa ttgacgccaa tcggacaaaa aataaggaat
     5341 agacacgagc aactccatca aaaatgggta cagcgagatg ctactgtatt tgaaaatatg
     5401 tcaaaagaag aatttgacac agtatttcgt tttatcggtc gatacagaga atttatacga
     5461 agtagcaaat gaagctacta ttttttattg tagtgataat aggcaaaaat cataagcaaa
     5521 aatccgaata ccgtcggaag aaatggtgct gcagcataaa gctgtcctgc gattagcggg
     5581 ccgatgacgc gcgatagaga ttgtatactt tgggtaccgc ccattacaag accttgctgg
     5641 ttatctgaga cagaattgga tagttggcca ttgaatacag gagtaaaaat agaatcaccg
     5701 aaaccataac agataatccc aaataaaaac aaaatcggca gtagaagaat tccagataat
     5761 gtgatgaata gataggcgag gatttcactg aacatcccta ttcttgtgat ctgctgttct
     5821 gaaaattttt tgagcaatcg aggcataatg aacaattgcg agacagtatc caagattcca
     5881 atcaaagaga agcttaaacc aaccaaccca gccttccact gaaaggcgtc aatcgaaaat
     5941 tgagaaaaga tagattgaag agagccagct gccaaccaaa cagcaaaacc tgctgtcaat
     6001 aaaggaataa cggatgaaat cttgaataat tgttgtaatt ggtgaaaagg tcttacatgg
     6061 gagaaactta aatctactga acgttttttt attggaaggc tttctagcat aaatgtgtag
     6121 ccataaacgg catttaagaa agtaaagagt gctccaataa atataggaac agaattcccc
     6181 aactcagcta atagaccccc tataatagga cccagcgttg ttcctatacc gactaaagca
     6241 cccatccatc caaaaacttt ggttctttca ttaggttccg tgatgtcggc aaagtaagca
     6301 tataaggtgg agatttctcc tgccgtcaat ccttcaatga tacgaccaag gaacaacatc
     6361 catatcgaat ttcctaaacc aaaaagcaaa tatccgatac ttgatcctaa taaactgata
     6421 ataaggatcg gatgacgccc aaaatgatca cttaagctac cgagaatggg ggcagataag
     6481 aaggcagcta gagcataaac agacatgagc aaagtgatat agaaagcttg ctgatgtatg
     6541 gagtgagaat aaggcagcgt taaaaacgga agtacaggac tgacgatagt aaatcctaat
     6601 ccagtgaata agacagagac gtatccaaaa actttagaat gtttatttgt gaaactgtac
     6661 atgtaaaaac tcctttatgc aataatgtta acttggaaac aaaaatagtg tatagtaatt
     6721 ttgtttcctt gtcaacattc taaggaacag cgaaatctac ttaatttatt tattccgaaa
     6781 agtgaagata cgcatcaaaa acatgaacaa acaaaaatca agtagacgac attgtaaatc
     6841 tgaccgatca gtgaagtaaa tagaaaagaa acctgttctt gcttcccatg ttttttttac
     6901 gtatactgtg attgagcgga ggagaaatca tgttgaattt agaaaattac ttaagcgctg
     6961 gacaaacagt catatctaat cttttactta aaaattatca taggatcggt ctacaatctg
     7021 aagaattttt atttgttcta cagttgcata tggcacagct tgaaggagat actttccctg
     7081 atttgcagat gattgctatg gatatgggaa tcaaacaaga tcagattttt caaatactgg
     7141 atcgtctcgt aacaaatgga tttatcaaga tagaaacgac gattgtcaac ggtaaaaaag
     7201 cagatcgata taatctttac cccatctatg atctattagg tgagtattta aaaacacaag
     7261 aaaaaaaata cgaagaaaaa acacaagaaa aagaaatcca gtcagtgtat caattatttg
     7321 aacaagaatt tggacgcccg ctttcttcga tcgagttcca gcggatcgga caatggctag
     7381 aagaagacca ttatcagccg gaaattttga agctagcact gcgggaagcc gtattaaatc
     7441 aggcttatag ttttaattac gttgaccgca ttttgctatc gtgggaaaga aaaaatctac
     7501 gtacaaaaca acaagtggaa gaagaccaaa aacgaagaaa acagcagctt cttcaaagag
     7561 aagtagaaca gtcagctcaa caagaagaat tgccgaaagt ctcactgaaa aattggttgg
     7621 aggagtagcg gaatatgtta agcaaacaaa aaacaatgga agctctagaa acgatgtatg
     7681 gaatgtttcc cgaagcacat ggagaactca agcacaataa tccatttgag ttattgattg
     7741 cagtgatctt aagtgcccag gcgacagatg tatcagtgaa taaagcaacg ccagatttgt
     7801 ttgcctcttt tccgacaccc gatgcgttag cagaagcttc aatcgatgaa atcattctta
     7861 aaataaaaac gattggtttg tatcgaaata aagcaaaaaa catcaaagcg tgtgcacagc
     7921 agctgattga acgtttcgat gggcaagtgc caacgtcaag agaagaattg atgtctcttc
     7981 ctggtgtagg cagaaagaca gcaaatgtcg tattggggga tgcattcggg ataccagcaa
     8041 tcgcagtaga tacccacgtg gaacgtgtct caaaacgcct gaggatctgc aaactagatg
     8101 ctacggtcat ggaagtagaa gaaacactga tgcggaaagt accacaagaa ttatgggtaa
     8161 agacacatca tacactgatt ttttttggta gatatcattg cacggcaaga aatcccaagt
     8221 gcgaggtatg tcctttgcta tcaatatgtc aagatgggaa aaatcggatg cgtctaaaag
     8281 aaaaggcgct aaaaaagaaa ccacgcctgt agacgtggtt tctttaattg caaataaatg
     8341 tatgaattat cttgttatta tggagaaaag ctgtttcgtt tatctttttt gcatgaaaaa
     8401 gtaaatgtac atactcagta gctaggatgg taacttatta caatttattg cgataaaaat
     8461 aaaagttgtt atttttattg ggaaaatacc cgatgtagaa aataatgcct tccaatatac
     8521 ctataaaata agtccagtat tccaaaggat tatataaata agtgacgtat ctatctaaag
     8581 gtgtaataaa aatgataagt gataataaaa aaataccatt tataactaaa cataaactaa
     8641 tggatttggg cggtttcagg ctcatcagaa aaatatagat tctggtgaac aacaaccata
     8701 aaaaagtgag aatcattgca tgagagcttc tttccataaa ttttccttta agagtagtgc
     8761 ttaaaagtac agaaaaaata ataaatgcaa ggataggagc aattaaagta aatttattta
     8821 ataataaaca aaatttttca gcttttttat tcttggaata acgaggtatt gttttcgata
     8881 aaaaaagatg gtgcagacaa attatgataa ttaagcatac tatcagataa ctcaaaatga
     8941 agccttcttt caaaaaatta ttcaaaacca tatattgtat tttttatttg ataataacaa
     9001 tgggattatt aagaagtggc actaaataaa agactagtgt gtatttagcc gatttaatta
     9061 taaacaagta aatggataaa gtatatgtaa tgataaaaga aaaatggatt ttctaatttt
     9121 taagctaaat gttagatcac acatgtatat gctggatagt cttataaaaa atcatgtaat
     9181 acagcttggt acatgatttt tatttgtagc tgttttttac atagacacaa aaaagaaacc
     9241 acgcttgtag acgtggtttc ttttttacta tctgtttcca gaagctgagg tgctgctgga
     9301 tggtgtatgg tcatttgcag catccgctcc gctagttgct ggctcactgg aagaagcagg
     9361 aggagcagat gaagacggtg tcgagctttc ttcggatgaa gaagaaggaa ccgttgttga
     9421 agacgctggc tcgcttgttt ctgctgtcgt gctttctttt gaggactcag cagttgattc
     9481 gctttgacta gtagagctag agctttgagt cgttgtctct gttgttgagc ttccaggagt
     9541 ctggacatag ctggaagatg gaatagttgt tgatggtgta attgcattcg atctagctgt
     9601 atattgatct ttgtagtaca gttcaccgcc cacacgaatt aatccgcttg gcatctccca
     9661 gtctgtattt gtcacgttag ctgaaacata ctgcataagc tcgcgataaa catcagaggc
     9721 tacgtgtgac gattctgaag tgacaggtgt cattttttta ttgtaacctg tccacacgga
     9781 aatcgaataa tttggcgtat agcccgcaaa taggatatct ggatacaccc cagaagaaat
     9841 accaagtttt gcatactcgt catctgtgta attggatgtt ccggtcttac cggcttgata
     9901 taacccagcg atttgcgcat tcgtaccagt tccttcagtg atcgtatctt ttaaaatgtc
     9961 tgtgatcata taagctgttt ctggagacat ggctgttttt ccatctggct cataagtttc
    10021 ttctgttccg tcttggaaga cgattttatt aacatattga ggtttgtaat aagtccctcc
    10081 attggcgaaa gccgcatagg ctgctgccat ttttaaggaa gaagctccgt attttgtccc
    10141 atcttgttct tccgtattac tagagatcgc attcgattga tggatcgtac tgtattcgat
    10201 cccaagattt tttaagaaag aagccacttt atctgaaccg acttcattga ataatttgac
    10261 tgctggaaca ttacgggata agtaaagtgc ttggcgtaaa gtaatggtgc ccatatattg
    10321 attatcccag tttcctacag gagtcgaagt cccttcatag ttatacggtg cgtcagtaat
    10381 agtttttcca gtagaatatt tcaaatattc aaaagctggt ccgtaatctg tgacaggttt
    10441 catcgtagaa ccaaaatcac gggaagtatt cactgctaag ttgttgccta aagttacgtc
    10501 ttctgcgatg tgacgtccgc caatctgggc ttttactttc ccggtattgg tgtcgataag
    10561 ggtggaggca acttgcatct cgtcgtctgg gtaagagaca tactgatccg tgttgacgat
    10621 atcatatagt ttcttttggg cgtccagatc caaattcgta taaatctcta aaccgtctgt
    10681 gtagacattc ttatctgttt tttcttgtac ttcattgatg acttctttga cataattatc
    10741 gacgatctta gtattgtcat cggattgagt tagttcttgc agaccatccg ttaccggtac
    10801 attaacagct tgatcatatt ctgtttgaga gattttttcg ttttgaagca tcgtatacaa
    10861 aacagtatct cgtcttttct tcgcctgatc tggataaaca taaggatcat aggcggaagg
    10921 ggcttgaggc atcccagcaa gcaatgctgt ttgcggtaaa gaaagttctg ataatttctt
    10981 accaaagtac atctcagaag ctgtctccat cccgtacaag ccgtttgaca tatacacttt
    11041 atttacgtag taggtcaaga tctcttgttt cgattttttt tgttccaatc ttacagccat
    11101 ccacgcttct tgggccttgc gtttcagagt ctgatcctcg gcactggtgg agaagaagga
    11161 aagtttgatc aattgctgtg tcaaagtact tccgccttgc agtccgccag aggtaaagtt
    11221 agagagggca gaaccgatga tccgaatagg gtcaaccccg atgtgtttat aaaaacggcg
    11281 atcttctacc gacacgatcg catcttctaa tgttttcggt aattcattcg cagaaatttt
    11341 ttcacgcttt tctgcgccta aatcttcgaa tagttcgcca tcttgtgtat atagtttgga
    11401 agatacggta gcgtctaatt ttttatccgt caattcgggc gcatcttttg cgtaatacca
    11461 gaaaagtcct acacctgcta aaaagaggat acagaaaaat gagagtattc ctaaaaggat
    11521 cttgataaat aatccttttt tatgtgttcc agaggacttt ccagaacctt tgccagaatt
    11581 cttcttcaca ctctttttag gagtaggctg tttctgtcgt ctagagcttc tagtttgttc
    11641 atttgccatt cttgctttct ccttcaatag ataatgttga taaatagaag tcaaccgcgt
    11701 ccaaataagg aatccgcgga gaaataccag ttttgatctc tattcctagt tcttcgatca
    11761 aagataaagg tagtgatttg cgtccttttt ccttttgggc gtcccagtaa gcaatcaaat
    11821 gaacactatt caaataaaaa cagcgcttca aagacgaaaa ccataacaag acaaagcaga
    11881 ccccattttg ttcgaggcat gctttcatat gttcgatttg atgggcatgg aagtttttaa
    11941 agggaaaaga tgttttgttc ttggtttctt ttgcttcaaa gtccaagtaa aagcctcgat
    12001 agacgccatt atagtctgta gttgaggctt gggtaaagta ggcttccttg atcacagcag
    12061 cacttctctt aggatagtct actttcacga tttggatagg ggtaggcttt ttatggataa
    12121 ccgccaaccc gcgggaaaga taatatttat tactttcatt gattgcttct tcaaagcgca
    12181 tcccccgatt gccgaattca gtgatctgat ttcttttttc ttgaattttt tcgacgggag
    12241 aggcattctt ataataaggt tggccatttg gatagcgcaa taccatcttt aatcacactc
    12301 ctaggccaca ttatagcaaa aaagcggata gaaagaaaag gaatctgaga tggataagtc
    12361 aaaagtaatc tatgtgtctg ggtatcgaag tttcgaactc ggtgttttta aagaaaatga
    12421 tcctaaaatc caagttgtta aaaatgtttt aaaaaaagaa ctccatcagt tagcagaaga
    12481 agggctggaa tgggtacttg tcagtgggaa tttgggcgtc gaactatggg ctgtgcaaat
    12541 agtagcggaa ttgaaagaag aatatccgga actatctctt ggtattttgt atcctttttc
    12601 tgattttggt aataactgga atgaagggaa ccaagaaaaa aaacaattag cagaacaatt
    12661 agcagattat gtcgaagctg ttagccatca accctaccaa tcacctagtc agctaaagaa
    12721 tcacactcgt tttatacttg agcatacagt gggctgtctg ctgatctatg atgaagaatt
    12781 ccctggaaaa acgaagtatt tttttgaaga tgcacagaat taccaagcag atcatcccta
    12841 cgaaattcgg ctgatcagta tggacgatct tcaaaatttt agtgaataat cgatattgtg
    12901 tttgatttat caactttttt cctatacaat gaaaaaggta gaaatgttat tacgtaaatg
    12961 aaaactagag gtgtaaatat ggcgaatttg gtttatagtc ctaaagacat tttacaacaa
    13021 gaattcaaaa caaaaatgcg cggctatgat cccgttgaag ttgatgaatt cttagacaat
    13081 atcatcaaag attatgaaac ttacagcaaa gaactccttg ctttacaaga agaaaacgat
    13141 cgattgagtg caaaagtagc tcaattatct aaaactcaag gagcagctca aacacgcgtg
    13201 caacaaacag aggcaccaaa gagcgcagca gtgaccaatt ttgatatctt aaaacgcttg
    13261 tcaaatcttg aacgtgaagt atttggtaaa aagcttgatc aacaagcaag tgcagtcaaa
    13321 ccagcacaac ctaatccaaa taactacaca aatgcagaca caagcttaga tgataatgaa
    13381 aaaacacgtc aattttaatt tttgattaat gaatttgcgg ttttcgggta atcgcggtct
    13441 gacttgatca ggctgaggaa agtccatgct cgcacaggct gtgatgcctg tagtgttcgt
    13501 gcttagcgaa accataagct aaggtactct ttggagtaac ggcaggaaaa caagctaagg
    13561 cttcggctat gcttaagtat ccttgaaagt gccacagtga cgaagcggct ggggaaaccc
    13621 atccggtgga acgcggtaaa cccctcgagc gagcaaccca aacaatggta ggggcgcttt
    13681 ttgtctggaa gaagaacagg acaaaaaggc agtataactg cagatagatg gttaccgctt
    13741 tgttttttct ccctggaaaa gcaaagtaca gaacatggct tatagaaaac cgcaaacatc
    13801 agggaattag gtcgtgacaa aagtaatgcg ttataagaaa caagaaaaac atttgaaagc
    13861 tatttttcaa tacttcagat gaatcgttct tattacaaaa caaacttttg tatcaccggt
    13921 tattcggaat ttgagtaaaa gtgtggggta ggactgatgt cccacctcct ttttttataa
    13981 ataaggagat tatgtatgga aaaaaacagg aagttcaacc tcgtcgcaac tgcggcaagc
    14041 gggctagaag cactggttgg taaagaatta agagatcttg gaatcgaatg ccaagttgag
    14101 aacggacgtg cacgttttga aggaacaatg gaaacgatcg ctacagctaa tttatggtta
    14161 cgtacagcag atcgagtaaa aatcgtggtt ggggaattcg atgcgtatac gtttgatgaa
    14221 ttgtttgaaa acgtaaaagc attgccttgg gaagattttc ttccactaga tgcagctttt
    14281 cctgtagctg gaaaatcgat caagtcgaaa ctatatagca cacctgattg ccaagcgatc
    14341 acaaaaaaag caatcgttga acgtctccgt acctattatc accgtccagc ttctgtacca
    14401 ctgacggaaa ctggcgcaca ttttcagttg gaagtagctt tgctgaaaga ccatgtgatg
    14461 gtaactctgg atacgacagg accaagttta ttcaaacgtg gttatcgctt agaaaaaggt
    14521 ggagcaccat tgaaagaaaa catggcagca gcacttatta tgttgacaaa ttggcgaaaa
    14581 gaccgtccat tttatgatcc tgtatgtggt tcaggtacgc tttgtattga agcagcctta
    14641 ataggccata atatcgcacc aggattcaat cgtgagtttg cttgcgaatc ttgggattgg
    14701 ttcagtcaag aaatcatgga aaatgttcga tcagcagccg aagaaaaagc agattatgat
    14761 attgaattag atattactgg ttcagatatc aatggacgga tgattgaaat tgccaaagcc
    14821 aatgcagaag aaatcggatt aggctcttcg attaccttta agcaacaagc agtcaaagac
    14881 ttcaaaacgg ataaagaata cggggtcatc gtggctaatc cgccttacgg agaacgtcta
    14941 ggagaagaag aaactgttcg gaaattatat aaagaaatgg gcgatgtatt ccgtccatta
    15001 aaaacatgga gtaaatatat cttgactagc gacttagcgt ttgaggaatt ttacggacaa
    15061 aaagcaacca aaaaaagaaa attgtacaat ggtgcattgc gtacggatct attccagtat
    15121 tggggaactc gtccgcctag aaaaaaagag aaagacgaat aatcttacta attgattcat
    15181 tcaattggat gtttggagga atagggaatg aaagaaaaag agtttttaca agaagtaaaa
    15241 gaaatcaatc ttctacaaca agctttagga atcctcgatt gggatacaca aacaggtatg
    15301 cctgaaaaag ctagtgcata ccgaagtgaa gtagacagct atctttacag catttatttt
    15361 tcaaaaaaaa tcggtccaaa aatcaaagaa gccattcgct atttttctga acatccggaa
    15421 gaattgtcgg aagttggaac tgccgttttt gccaaagtaa aagaagagta tgatttggaa
    15481 catcgcgtac cggaagatct tatgagaaaa tatacagctg ccgtttcttc agcacacgga
    15541 caatggcaaa aagctagaga aacacaacaa ttttctgatt ttcaacacgc attgaatcaa
    15601 aatattgaat taacaaaaca gttgatacct tactggagaa aagatgaaaa gacgaattat
    15661 gatgttttgc tgaatcaata cgaacccggg atgactgtcg aaatccttga taaggtattt
    15721 gatcagctta aagaaggaat tctttcgatc cgccgtacgc tccaagaaaa agggactgaa
    15781 cctgaaacag actttttaaa tcggagaatg acgaaaaaac aacagaagag atttgtagtg
    15841 aaagtaatcg aacaacttgg ttatgatttt agtcgtggtc gtttagatga cactgtccac
    15901 ccatttatga ctggaattaa tccgaatgat gcacgaatca cgacacgatg gaacgaaaca
    15961 gatttcaaaa tggctgtttt tggagtgatc cacgaggctg gtcatggtat gtatgaacaa
    16021 gacatcgatg ataaatatgc gtatacaccg gtttatgaag gtacatcaat gggtatccat
    16081 gaatcacaat cgttgtttaa cgagatcatt attggaagta gtcgcagctt ctggaaaaag
    16141 caatatcctt tctttcaaga atgtgcagaa ggaacattcg atgatattcc ttttgacaaa
    16201 ttttatcgtt cattgaacca tacaaaatca agtttggttc gtatcgaggc agacagtttg
    16261 acttaccctc tccatatcat cattcgttat gaaatcgaaa aaatgatttt caatgaaggg
    16321 gtagatgttg ctgaactacc tgaaatatgg aatcaaaaat atgaagagta tctgggaata
    16381 cgaccaacaa atgatgtgga aggcatccta caagacgttc attggtcagg tgcaagcttt
    16441 ggttattttc cctcttatgc attagggtac atgtatgcgg cacaattact tcattctttg
    16501 cagcaagaaa tagatgtgga aaatgttcta gcgtcagacg attattctcc aatcaaaaac
    16561 tggatgtcag agcatatcca tcaatatggt gcatctagaa aaccaaatca attaatcatg
    16621 gatgcaacac atgaaccgct taatccgcaa tacctgatcg actatatgaa agacctgtat
    16681 tttaatgtat atcaggtaaa ataaaataca atttacaaag atagctgaaa ttcatctaat
    16741 ctatagatgt tttcagctat ttacttaaga aagaagtgga acgaatggat aaattacaag
    16801 tgatcgctga ttatagtatg gaccaattag cgcatgatca aacaggacat gggagcgatc
    16861 ataccaaaag agttgtcaag ttagctgaaa aaattttgga gacggaaccg caggcagacc
    16921 gctttgtgac gcttgcagca gcttacctac atgatacgat tgatgataaa gtcgttaaaa
    16981 atgagaacga ggcaaagcaa cagcttcgtg tattccttcg ctctttgcca atagtagagg
    17041 aacagatctc gatgattttt tccattatcg aaaatatgtc cttttctaaa aatctctctg
    17101 aagcggccga actatctctg gaaggtaaga tcgttcaaga cgctgatcgt atcgaagcat
    17161 taggagcaat cggcattttg cgtactgctt atttcggcgg tggacatggg cacccgattt
    17221 ttgatcctga actgtatccg caaacattca aggacaaaga aaattaccga aaaggcacga
    17281 cagtgatcaa tcatttttat gaaaaactgt tcttgctgtc tgataaaatg aatactgatt
    17341 acggatatga agaagccaaa cgaagagaaa ccttcatgcg tgaattctta gaagaatttt
    17401 ttctggaatg gtctattgac gatgaaaatt ttactccaga caattggatc aaaaataaca
    17461 aaaaatgatg gaggttgtga cagaagtggt cagctccaag atatttcgga tcattttccg
    17521 taaaagttac ttctggaaca ctgtttacca agaggtcgtg agcctgccgt tcagctccga
    17581 gtcacaagga acaatttcaa aaaatagctt ctcgtgtttg atgaatattg taacttgtga
    17641 ttcggaattg gcaggagaac accgtttatt cggaagaata ggactgtgac aagacttttg
    17701 tcacagtcct tttttcgaat tcaacaagta aaacttttaa gaaatattca gagagtaaaa
    17761 ttaaaaattg ctgataaacg aagatggaaa ttttatgtat ttttattggt ctatgcaata
    17821 aataaattaa atattcagaa tacaattgat tttaacgaaa gggcttctat caatggttgt
    17881 gttgtattta tctgcccagg tagagtaaaa tagatcatta tctaaaaggt aattgttcat
    17941 actatataag tcatttgaaa gtaaaaagat actgtaaata aaaaatgtgg ttaaataatt
    18001 ctcataatca gtgtaagcgt tatcaaaaat atagcatact tgctttgtag atgaatgaca
    18061 cgatatatgt ttggtatgtt ctgcaagaca gatgaatatg gaggtggaga caatgtcttc
    18121 caaagaacta acaatgtatt tagagaaaga attggatcaa ctgaaagaaa aggggttata
    18181 caatacgatc gacatactag aaagtgaaaa tggtgcttgt atcatcgtag acggaaaaaa
    18241 gatgatcaat ctagcatcca acaattatct tggatttgcc aatcgcgaag aattgaaaaa
    18301 agcatgtatt gaagcaaccg aaacttatgg tgtaggagca ggagcagtcc gaacgatcaa
    18361 tggttcgctg aaaatccatc agcaattaga agaaaaaatc gcagaattca aagggacaga
    18421 agcagcaatc gcctttcaat ctggattcaa ctgcaatatg ggcgctatct ctgcagtaat
    18481 gacaaaagaa gatgctatct tatcggatga attaaaccat gcatctatta ttgacggttg
    18541 ccgcttatcc ggagcaaaaa tcatccgaat taaacatcaa gatatgaaag accttgagaa
    18601 aaaagcaaag gaagcgatag aaagtaagaa atataaaaaa atcatgtata tcacagatgg
    18661 tgttttctcc atggatggag acattgcacg attgccggaa attattccga ttgttgaaaa
    18721 atatggactg atcacctacg tcgatgatgc gcacggctca ggcgtaactg gaaaaggtgc
    18781 aggaaccgtc aagcattttg gattaagcga caaaatcgat atgcaaatgg gcacgttatc
    18841 gaaagctata ggtgttgttg ggggttatgt agctggatcg aaaacactaa tcgactggtt
    18901 gaaagctaga agtcggccat tcctattttc tacttcgcta actccaggtg cagctgcagc
    18961 tgcattggct tcgattactt tgatgcaaga acatccggaa cttgtcgaaa aagtttggga
    19021 aaatgctaat tattttaaag aagaattgaa aaaagtaggc tataacatcg gtatgtctga
    19081 aacacctatt actccagtca ttttgggaga cgaaaaagtg actcagactt tctctaagaa
    19141 gctgatcgaa catgggattt atgctaaacc aatcgtttat ccaactgtgc ctcttgggac
    19201 aggcaggatc agaaatatgc cgactgcgga acatacgagg gaaatgcttg atgaagcagt
    19261 agcagtttat caaaaaatag gaaaagaaat ggaaattatt taactaaatt tagttttttc
    19321 gtctatttaa aattagagaa catgttcacg catatattgt taatcatctg aagatagtag
    19381 taaaaaagat cagggaggat catcatgaaa aaagtattgg tgacaggatg tttaggacaa
    19441 attggttcag agttgatcac acggctacgt caagaactag gcagtgaaaa tgtcattgcg
    19501 acagatatac gcatgcctga agtcattgag aaaaacgata tctttgagat cctagatgta
    19561 atggattacg aaaaaatgcg cagcatagca gaacaatatc aagtggacac attgattcat
    19621 ttggctgctc ttttgtcagc tgttgcagaa gcaaaaccac aattagcctg gaatttgaac
    19681 gtgactgggc tggtcaatgc attggaagtc gctagagaat tccagctgaa attttttacg
    19741 ccaagttcaa tcggcgcgtt tggtccaaat actccaaaag atcatacccc acaagatact
    19801 cttcagcgtc ctacaaccat gtatggggta acgaaggtag ctggagaact actatgtgat
    19861 tattattatg tgaaatatgg cgtagatact cgtggtgtcc gtttccctgg attgatttct
    19921 tatgcaacct tgccaggagg cggtacgaca gactacgcag tcgatattta ttattcagca
    19981 atcaaagaag gaaagtacac tagtttcatt gatcaaggta catcaatgga tatgatgtat
    20041 atgccagatg cgatcgatgc cattataaaa ctcatgaatg cagatcctga tcgattggtt
    20101 catcgaaatg ccttcaatat atcggcgatg tcttttgacc cggaagagat caaagcatct
    20161 attcaaaaaa tcataccaga ttttgaaatg gattatgatg tggatcctgt acgtcagtca
    20221 atagcagaat cttggccaaa ttcactagat gtttcttgtg cgcaagagga atggggcttt
    20281 tcgccgaaat acgacttaga tgtgatgaca aaggatatgt tggaaaaact gaaagaaaaa
    20341 ttggtagaga cggtataaaa caagaaccac atccaaaaag ttttttatac ttttgggatt
    20401 ggctatggta tgaaagggga caagggatgg aagaatatca agccacgcca gtaaaagaag
    20461 taaaaataga aaatgaatta aaacgtacga tgggattttt tactgcttta tcgactgtta
    20521 tgggcacagt gatcggtgca ggggtatttt ttaaagccgc aagcgtagca gaagttacag
    20581 gatccgccag tttgcatatg ttttcttggt ttctcggtgg tatgatttct gtctgtgcag
    20641 gactaacagg agctgaactg gcagctgcta ttccagaaac aggagggatg attaaatata
    20701 tcgaacggat ttacggaaat acagcagctt ttttattggg ctgggcgcaa gtcgtgattt
    20761 attttccagc aaatgtagca gccttgtcga tcattttcgg tacacagttc gtcaatctat
    20821 ttggtctttc ccagtcaatg attgttcccg tagctgttac agctgctgta tcgatcctgt
    20881 tgatcaattt tttaggttct aaagctggag gggcttttca gtcgattacg cttgtctgca
    20941 agcttattcc tttgtttgtg atcgtcattt tcggtttgtt ccgacaagaa ggagtagact
    21001 tccaactgtt tccgatccaa gcaggagaaa atctttcatt tttctcagcc ttgggagcgg
    21061 gcttgctagc aacgatgttc gcatacgacg gttggataca cgtaggaaat atttcgggag
    21121 aattgaaaaa gccggcgaaa gatttgccaa aagcaatttc tttaggaatc atcggaatca
    21181 tgatcgttta tttattagta aatgcggtgt tcttaagaac cgcatctatc gacggagtcg
    21241 caggaaacag caatgcggca agtgacgttg caaaaatgat ttttggcggc ttcggtggaa
    21301 gactggtcac agttggtatc ttgatttctg tttatggaac catcaatggc tataccctta
    21361 ctggaatgcg tctcccttat gttatggcaa aagaaaacaa cctgcctttt agcaagctct
    21421 ttgctaaact tcatgataaa actaaagttc ctgtagccgc aggtatctta gagctagtca
    21481 tcgctattgg catgatgatg atcggtggtt ttgatacact aacggatatg ctgatctttg
    21541 tcatttggat tttttatacg atggtctttg ttggtgtcat tcttcttcgt aaaaaagaac
    21601 ctgatttgtt tcgaccatac aaagttccaa tgtatccgtt tattccacta gtagcaatca
    21661 ttggagggac ttttatcgta tcaagcacgc ttatcactca gaccttttta gcttcgatgg
    21721 ggatagtatt gacacttgct ggtatcccga tttatctcta tttaaaacgt agatagctaa
    21781 aacattcgaa ttttattaga actgcacttc tctgccaaac aaaatatttt atttaaatga
    21841 ggagtacgtg gaagaaatgt caaaagtact cgttaatttt gatcacgtaa atgtcgtttt
    21901 gtctacgatg aaatagcaaa gtaaaagaca gaaatcgggc tcaaccgatt tctgtctttt
    21961 actttgattt gcgtaactga actattcggc gtacgccgcg ataaatattt aataaaacca
    22021 agcaaccaga aatgaaaatg ggaagccaaa tcagatagac agggtagcca agcactttag
    22081 acaaagcatg tggagtcatt ttatccattt caagaagtgc ttgctgccaa gtctgaagat
    22141 tgaagactag catgaaaccc gaaataatca ggagaataaa tcctaaataa tgaattgtag
    22201 ttctttttct tacataagcg atcgtagcat aaaggaacag taaaaaaata ggtacgccaa
    22261 aaacaaagta catattcagc atctcgacac cccctttgtg tttatcttac tttactttga
    22321 aagaaatgag aaataatagc ctcgttactt gcttgaaaca gcaaaggact gctaagataa
    22381 gagagataca aagaatcaag gaggagtcat atggcaagtt atatcgaacc gattcgtttt
    22441 gcgctgattg tttttccatt tttagcctta gcgatctcat ctgttttttt tatttatgaa
    22501 tatcgaaagt atggaacatt tctagtaaca agggcagtta ttttgtattc tttcgttttt
    22561 tatttattgt gtgcgtattt tttggtgatc ttaccacttc cggcaaagga gacggttgcc
    22621 caaatgacag ggccaaagat ggagctgcat ttatttgctt catggcaaca tttcagagac
    22681 aacacggtat tggtcttgtc tgaacctagt acctacctgc cggcaatgaa gcagagtgta
    22741 tttttggaac cagcttttaa tgttttatta ctcataccat ttggcattta tttaagatat
    22801 tatttccggc tttcttttat gaaaacgatg attgctagtt tctgcctttc tctatttttt
    22861 gaattgacgc agctaagtgg actttatttt atctacccaa gaccataccg cttatttgat
    22921 gtgaatgatt tagtgacaaa tacattgggt ggaatcattg gttttgtcgt tacgccgtta
    22981 tttacattta tgcttcctac aagaagacga atggatgaac tttcttatga aaaaggaaag
    23041 actgtctcat tgactcgacg cttggtcgct tatttgatcg actggacatt tttatctctt
    23101 attaatttgg tagcggcgat tttctttaaa attgcgttcg attcaggggc agttacttct
    23161 catatctggt ggcttttatt agaagtaggg gtatacttta tgattgtacc gtttataacc
    23221 aatggatgga cacttggcaa aaaaattgtg cgtatccgtt tggtggaaga agaccgcgaa
    23281 cgaatttctt taaaagcatt gatgatccgc tacgggtatc tgtactttct tttttatggt
    23341 ttaagctggt tggggcagtt gcttcagcaa atcatgaatt cgacaacgaa tacggtgttg
    23401 cagatgagtg cagtattcat ttctctcggt gtcttgttac tacaaggtat ttttatttta
    23461 aatatcttgc tatcattttt gagaaaaaaa cggattctgt tttatgaaaa agctagtcac
    23521 acatatactg ttagcacgat tggccaaaca aaggatgatg attctcgaaa ttagctgagc
    23581 aaaaacgctt tgtctgtgtt ataatgccaa agtcgtgata atttaaagag aagaggtgca
    23641 cgaatgaata attttgatat attccgcttc aaaccgttta tcaatgaagc gttaaccgca
    23701 aagggcttca aacagcccac agaggtccag gaacgtttga ttcctttaat tgcaaaagga
    23761 aaaaatatca ttgggcaatc tcaaactggt acaggaaaaa cacatacgtt tttgttgcct
    23821 ttgtttgaaa aaatcaatgc agaaaaagag gaagtacaag ttgttattac agctccaagt
    23881 agggaactag ctgcacagat ctatgaagca gctacacaaa tcgctaaatt ttctacaccg
    23941 gagatccgtg tctcgaattt tgtcggcggt acagacaaac agcgtcaatt aaatcgtctg
    24001 catcaccaac agccacaggt tgtagtaggc acgcctggta gaatattaga catgatgaat
    24061 gaacaagcgc tgaagattca caccgcattt gcatttgttg tcgatgaagc ggatatgaca
    24121 ttggatatgg gttttttaaa tgaagtagac caaattgcaa gtcgattacc agaaaagctg
    24181 cagtttttag ttttttctgc cactattcca gaaaaacttc gtccattctt acgaaaatac
    24241 atggaaaatc caatcattga agaaatcaaa ccaaaagcag ttatttctga agacattgaa
    24301 aattggctga tttcaacaaa aggtaaagat gagaatcaaa tgatttatca actgctgaca
    24361 attggtcatc cttatttagc aatcgtattt gccaatacaa aacagcatgt ggatgaaatt
    24421 gccgattact tgaaaaacca aggcttgaaa gtagcaaaga ttcatggaga catcacccca
    24481 agagagagaa aacgagtgat gcgacaagta cagaatctgg agtatcaata tgttgtagcg
    24541 actgatttag ctgctagagg gatcgatatc gaaggtgtct ctcatgttat taatgcagaa
    24601 attccagaag atctagactt ctttatccat cgtgtcggac gtactggacg taatggctta
    24661 aaaggaacgg ccattacgtt atattcgcca aatgatgagc aagccattga tgcgatagaa
    24721 aaattgggcg tctcatttga accaaaagaa atcaaaaacg gggaaatcgt caaaacatac
    24781 gatcgtaata gacgtgccaa acgagaaaaa tcaaaagatg tattagatcc cacgctgatt
    24841 ggtcttgtga agaagaaaaa gaaaaagatc aagcctggtt ataagaaaaa aatcgattgg
    24901 gcaattgcag aaaaaaataa aaaagaacgc aaaatcgaac gcagacagca aagccgtact
    24961 gctcgtaaaa ataagaaaaa ttcacataaa taaaaaacaa gaggttgtga caaaaggcgt
    25021 gtcacaatct cttgttttta agctagactt tttttcattc cgatacaaag tacttcatct
    25081 tcaataaaag gttctgtgca agtatgatac ccttgttttt cataaaaatc tacagccgtc
    25141 atttcagcta ctacataact agtctgacaa ccttctgaaa ccgcccgttt ttcagcagct
    25201 tcaagcaact gaccgcctaa cccttttcct cggtattctt ttgctacgca aaatcgttcc
    25261 ggcttgaagc aagtaggtgt tttcttttca taacgcaaag tagctactgg tcttttttga
    25321 tcaagaaata gataataggt ttgttgcggg atatcttttc cgtcgaattc tagttctgca
    25381 ggaatccctt gttctaatac aaaaacttga tatctcaaaa agcagctagc tgcgcgtatc
    25441 cattcatccg ctccaactat ttttttcatc atattcctcc ttgtcatgaa tagcagagat
    25501 gtattgattc ctttattctt atcgtaccaa aaatcgtgga gtatgaccaa aaggaaatga
    25561 aaataaaaat tgagatattg acagtgatca atagaatgcg tatactaaat aagtacgaaa
    25621 aggatatgat ttgtttttta agactcacag aaaattcttt cttggctgaa aaaagaatag
    25681 tcactaatca aattgctccc tttttctatt ttggtagaaa taccgacgca gctcagcgtt
    25741 atcgagttta agaggtaatg attacacatc attgcaatca aggtggtacc gcgagttttc
    25801 gtccttggct gtgatggtgt ttttttgtat ttaatttata gaaagcaggt aatgacatga
    25861 aacaattaag tagtgcacaa gttcgacaaa tgtttcttga tttcttccaa tctaaaggac
    25921 atacgattga acctagtgcg tctttgatcc ccgtgaacga tccaacctta ttgtggatca
    25981 actctggtgt tgcaacattg aaaaaatatt ttgatggttc agttgtgcca gaaaatccaa
    26041 gaatcacaaa tgcccaaaaa tctattcgaa caaatgatat cgaaaatgtc ggtaaaacag
    26101 cacggcacca tacgatgttt gagatgctgg gtaatttttc gattggtgac tatttcaaaa
    26161 atgaagccat ccactgggca tgggaatttt tgactgatcc aaaatggatg gcattcgatc
    26221 cagaaaaact ttatgtaaca gtttatccaa aagatacaga agcaaaacgc atctggcatg
    26281 aagaagttgg cctgccacta gatcacatta ttgatgtaga agacaacttc tgggatatcg
    26341 gtgcaggccc atgtggtccg gatacggaaa ttttctatga ccgtggagaa gcttataacg
    26401 atttagcaga agacgatcct gaaaactatc caggaggaga aaatgaacgt tatttagaaa
    26461 tctggaactt agtattttca gaattcaacc ataagcctga taacacattt gaaccacttc
    26521 ctcataaaaa cattgatacg gggatgggat tggaacgcat ggtctcaatc gttcaagatg
    26581 cgtcaacgaa ctttgagaca gacttgttta tgcctattat ccacgccgta gaaaagctaa
    26641 gcaaacaagt aaaatatggt gaaaacccag taacagatat ttcttacaaa gtaatcgcag
    26701 atcatattcg cgccctttca tttgctattg gcgacggtgc attgccatcg aatgaaggga
    26761 gagggtatgt cttacgccgt ttgcttcgtc gtgctgtcat gcatgggaaa aaattaggta
    26821 ttgaacaagc attcttatat cgtttagtcc ctgttgttgg ggaaatcatg gtaagttatt
    26881 atcctgaagt acttcaacaa aaagaattta ttgaaaaagt tatccgtaca gaagaagaac
    26941 gtttcaatga aacaatcaat gaaggtttgg aaatcttaaa tcaagtgatc caagaagtaa
    27001 aaaacgaaaa cgggacgact ctagcaggaa aagacatctt caaactatac gacacatatg
    27061 gcttcccggt agaattaacg gaagaggtgg cagaagatga aggactgaaa gttgatcatg
    27121 ctggttttga aaaagaaatg gatgcacaac gcgaacgtgc tcgctctgcc cgcagtactg
    27181 aaaaatcaat gggggtacaa tctgctttat tgacagatat caaagtagaa agtaaattca
    27241 ttggatacac agaacaagaa tcagatagtc aattattggt catcgttaaa ggtgagtctc
    27301 ttttgaatga agtcgcagaa ggtgaagctc aaatgatctt tgatcaaaca cctttctatg
    27361 cagaaatggg tgggcaagta gcggatcaag gatggatcat gaatgaagta ggcgaaatcg
    27421 tagcagttgt tacagatgtt caaaaagcgc ctaatggtca atttatgcac accgtagaag
    27481 taaaagcacc aatgagtgaa ggacaaacct atcatctatt gatcgatcaa tcgatgcgca
    27541 atcggatcat caaaaaccat acagcaaccc atctactgca caaggcattg aaagaagtac
    27601 ttggcgagca tgcaaatcaa gctggttctt tagtcgctcc tggacattta cgattcgact
    27661 ttacccactt tggtcaaatc acttcagatg aattagctga aatggaaaga atcgtcaacg
    27721 aaaaaatctg ggaagctatc ccagttgaaa caattgaaac agatatcgat acagccaaaa
    27781 acatgggtgc aatggctttg tttggtgaaa aatacggaca tgacgttcga gtagtaaata
    27841 ttggcggctg gtcaatcgaa ctgtgcggag gcacacatgt agcaaataca gaaaacatcg
    27901 gaatcttcaa aatcgtttct gaatcaggaa ttggtgcagg cgtgcgacga atcgaggctg
    27961 taacaagtaa agaagcgtac gaactacttg aagaagaaga aaaacaacta aaacaagtag
    28021 caacaattgt taaatcacct caattgaaag aagttgtttc aaaagcggaa caattgcaac
    28081 agcaagtaag agagctacaa aaggaaaatg aacaattagc tagcaagtta gcgaatcaac
    28141 aagctggtga tgtattcaaa gatccagaaa cgatcaatgg aaaaacaatc attgcagcac
    28201 aagtaaaagt gaaagatatg aatcagctgc gtcaattagc tgaccaatgg aaacaaaaaa
    28261 atatttcaga tattcttgtt ttagcaaacg aacaagaagg aaaagtcagt ctgctagcgg
    28321 caatgacgaa agaatcaaat gaagctggac taaaagctgg cgacttgatt aaagcaatcg
    28381 caccgaaagt aggcggtggc ggtggtggac gtccagacat ggcacaagct ggcgggaaaa
    28441 atcctgctgg tattccagat gcacttaaag ctgcgaaaga atgggttgcg caacaatagg
    28501 gcgtttacgt ttgacagaaa aacaaaagtt caaacattga acgaaacatg attatggggg
    28561 cgaagacaaa caagtcttgc cctcatactt ttttcaattg gatggcgcat ctaatcaaat
    28621 ggtcggattc ggatggtctt tagttgacga aagtgacaga aatttttacg attagtataa
    28681 ataaaaaggg gtgaaaaaat gaatagtaga aataagacct ttcgactagt cttacgtgcg
    28741 atcttgttag caatcatcat cgtacaagcg atggttcctt ggctggggtt tattccatta
    28801 ggattcatta gtttaacaat tatccatatc acagtaatta ttgctgcagt agtattaggc
    28861 ccaaaagatg gcatggtgat tggcttgttt tggggaatcg ctacaattgt tcgtgcctat
    28921 gccatgccaa caacgccatt tgatacatta gtgttcacga atccgattat ctcggtagtt
    28981 cccagagtac ttgttggctt agtagcaggc ttggttttcc actggattta tcaaaaaaat
    29041 aaatcaataa cgatcagctc agcctttgca ggggtactgg gttcattggt caatacagtc
    29101 ttagtgttag gattcatggg attattttat acaggtgcaa cggcagatgc ctatggtgta
    29161 gactctgctc ttttatttaa aaccttagca ggggttgcag caatcaatgg gataccagaa
    29221 gcaataggtg cgggaatcat aacaccatta ctagcaaaag cgttatttgc agcaacaccg
    29281 ttgaaaccag aataatgacc atcttttaat agtaatagga cgcacgatag atagaaaaag
    29341 gaagagagga gaggaaaaca atcgtcctct ccatcttttt acctgagcaa caagcaaact
    29401 agaaggggta aaaaacttgg ctaagaaaca agaagaaaaa aagaaacaaa taccgcaaca
    29461 gcggacaaaa aaaggagtac tagcgggtat cttaggattg gttacgaatc tgatcttgtt
    29521 tgtctctaag ctaatgatcg ggcttttttc aggaagtgtc tccattatgg ctgatgcagt
    29581 gaacagtcta tcagatactg cttcatccat attgactttg atcggattta aaattgctgc
    29641 aaagccagca gatcaggaac atccttatgg acacgaacgc ttcgaatata tcagtgggtt
    29701 atttgtttcg atcatcatta cttatgtagg atttcaattt ttagagtctt ctgctgaaaa
    29761 aatcatccat ccagaaaatg tctctttaac acccatcgtc ttttttgtcc taatcatttc
    29821 catctttttg aaatttgcac aaggcaaaat gtatcaggtt attgcgcaat ccattgattc
    29881 tgaaacattg agagctacag caacagatag ttataatgat gtctttacta cactggctgt
    29941 attgctttca gcagcaatcg aatgggtaac tggatggcgt attgatggat atataggttt
    30001 tgctttagca ttatatatcc tttatagtgg attgacgatg cttcgaaatt ttgtatacga
    30061 actattagga agtcgcccaa cgccagcaga gattgaagaa atggaagagc atttaaatgc
    30121 ttgcgatgat atacttggct atcatgattt attggtgcat aactatggac ccaataaacg
    30181 ctttgcatca gtccacatcg aagtagatga atcaatgaat ttgaatgtgg ctcataagat
    30241 tattgatctg atagaaaaag actttaaaaa gtctttggat gtggaacttg tctgtcactt
    30301 ggatccaatg cctgttgata acgaaaaata ctataatatc ttgcggcagt taaagcaaat
    30361 tcttcttgaa acaggtacag ggcttaatat tcatgatttt agagtaattc atcaaggaaa
    30421 aacgctgcaa tttgatgtag tggtccctga gaaattccag tttgttgata cagaactaga
    30481 aagaatctta cgtagtcaaa tagaagaaaa aatcggagat taccaattgg aaattacgtt
    30541 tgatcacaat tatcttttat attaaatgag aaactataaa aagactcctt aaagttttta
    30601 atttaaagag tctttttttc ttttaattgt ttatggagag cctgacgtgc aagattatct
    30661 gctcctttat ttttgttttc gggcaaccat tgcaggatca ataaagaaaa ttcggataga
    30721 agttcttgga ttctttgaag gtagggaagg aagagctcgt tcttcgttgc gtttttgtcg
    30781 accgtagaaa ctagtgtttt gctgtctgaa aaacagaaaa tcgtttcatt ctgtaagtcg
    30841 tttttcttta gaaattctaa agtttttaaa aagacttcga actctgcttg atggtttgtc
    30901 cctatagaaa gcgggataga tagctgttct tgtttacctt gatagacaat caagattcca
    30961 cctccactag gaccagggtt gccttttgta gaggcatcaa tgtatacttt taacataaaa
    31021 agagattctc ctttttgttc aaactaatgt tatggtaaga ttatatcatt actgaatcgg
    31081 tgagaggtta gagaatgaaa aaaaatattc gatggcagcc tgaactggca catacgatca
    31141 tctattggtc attgaccttg atcattctgt tttttagtct gattctttct ttagaaaaca
    31201 caggtcctta ttggaaaagc aattttgttt taggtatttt tcttgttttt ctatttctag
    31261 gtttgcggcg ttcttttatt ttaaaatcaa actctgtgat tatacgttat gctgcttttt
    31321 ggaaagaccg agaaatatct gtcggacaga ttcgatcttt gacgccaact aatactgggg
    31381 tgcaaatgat gttgcaagat gagaaagccc catctgtttt catgatgcga aaaaaagatc
    31441 aagtagtcct ttttgatcat tttgaaaaaa acggacccaa atcagaatca attccttatc
    31501 cttatacgaa aaaaagaaaa agctaatttt aaaaatcaga acctaaaaaa acgaattttt
    31561 acaggaaaag aaaagagtga gacgtacggt tcatcccgtt tagcgtctca ctctatttgt
    31621 ttatctattc atgcatacta gtatcggtag tctgaacgtt gcctttcttg acatgggcag
    31681 cttgtgttcc tcgattccct tcgatgatct caaattcgac cacttgattt tcttccaaag
    31741 ttttgaatcc ctcttcttca atcgcagtaa aatgtacaaa aatttcttct gtgtcatcat
    31801 aactgataaa gccgtatcct tttttgttgt caaaccattt tacaattcct gtggtcaaag
    31861 cactcacgac ctttctaaag tctgatcata gccttcatta taaagagtat ttataagtac
    31921 gtcaaataaa ttaaaaacct gtaattttat gttttttttc tgaataaaaa aaggtataat
    31981 tggcatatct taacaaagaa gatattttgt tgaataaagt tcgtgaaaag gggtaatcaa
    32041 atgaagaatg atctgcaaat ttcacaagaa acagagctag aaccgattgt tgaagtggct
    32101 agtaaattag atcttaagga agacgatttg gaactgtatg ggaaatataa ggcgaaaatc
    32161 aatttttctg gaatcaatcg atcaaaggat aacgctgagg ggcatttgat cttagttact
    32221 tccatcaatc caacaccagc tggcgaagga aagtcaacga tcactgtagg gttaggagac
    32281 gcgctcaata aaatcaataa aaaatctgtt attgcattgc gagaaccctc acttggtcct
    32341 gtgatgggaa tcaaaggtgg tgctgcaggc ggaggatatg cacaggtatt gcctatggaa
    32401 gatatcaact tgcattttac tggtgacatg catgctatca caacagctaa taatgcatta
    32461 tctgctcttt tagataatca tattcatcaa ggaaatgaat tgaacatcga tgcccgccga
    32521 gtgatttgga aacgggtagt cgatctcaat gatcgtgaac tgcgtaaagt aattgttggc
    32581 ttgggtgggc caatccaagg tgttccaaga gaagatgggt ttgatatcac agttgccagc
    32641 gaaatcatgg ctatcttgtg tcttgcggca gaccttgaag atttaaaggc tcgtcttgca
    32701 aggatcgttg tcggctatac atttgaccgt cagcctgtga ctgctggaga cttgaaagca
    32761 gaaggcgctc tggcattact gctgaaagat gcaatcaagc cgaatcttgt acaaacaatt
    32821 tacggaacac cagcttttgt ccacggggga ccgtttgcca atatcgctca tggctgcaat
    32881 agtattttag ctaccaagac agcattgaga ttagcagatt acgttgtcac agaggcagga
    32941 tttggtgcag atcttggcgg agagaaattt ttagatatca aagtacctaa cttgaaaaaa
    33001 gcgccggatg ctgtggtgat tgtcgccact gtccgtgcat tgaaaatgca tggcggaatg
    33061 aaaaaagatg aacttaaaaa tgagaatctt gatgctttga aagtaggttt tgcaaattta
    33121 aagcgccata tacgtaatat ggaacaatat cagctacctg tgatcgtcgc aatcaatgaa
    33181 ttcgtaacag atacagacaa tgaactcaca ctgttggagc acttgtgtga aaatcagggg
    33241 attcttgcca agagagcgag tgtatgggca gatggagcag aaggcggcgt tgatttagca
    33301 aaagctgtag tacgattgat tgatagaaaa gaagctaatt acaagccatt ataccgccta
    33361 gaagaaacga tacaagaaaa gacagaaaca atcgtcaaga aaatttacgg aggaaatggt
    33421 gttgttttca gcaaaaaagc gcaaaaacaa atagaagagt ttacgaagaa tggatgggac
    33481 aaactgccga tttgtatggc aaaaacacag tattcatttt ctgatgatcc ttcactgcta
    33541 ggtgcaccgg aagatttcac catcacgatc cgcgaaatca tcccaaaatt aggggcagga
    33601 tttttagtag ccttgactgg agatgttatg acgatgcctg gtttgcctaa aaaacctgct
    33661 gcattgaata tggacgtgac aaatgacgga gaagtgttgg gattgtttta agcttgatta
    33721 taatctacca tcgaaggagc tgtattttga ctacagcttc tttttttaga cgatagggaa
    33781 ttaattttgt ttacactagg atcattcttt ttctttattg tattttgagc tatactaaag
    33841 cataatagga gggtatgatg aaaacgacat ttataagaaa aaccggtttt tacggtatgg
    33901 gtagctcgat tcagctaaga atcaacaatg aaaaacgcag tgttctcagt catgaacaaa
    33961 agataacgct tgatctggaa gtgcccttta cgatgcaggt caccttttat tggctaaaaa
    34021 gccccgttta tacagtgaaa gaagcaaagc ctgcttatgt gatcacaatg aattacttga
    34081 ttcttcaaat ctatccgttt ttatttctag caactgggtt gggggccgtt ttcctacaaa
    34141 atttattttt cagttttttt gcagttattg tgttgattgc gttctttttc tatataaaaa
    34201 accgggcata tttgatcaag gaggaaaatt atggcaaact ctgatctttt tttaatcagt
    34261 ttcaatcgaa tcgaaaaatg gatgagagac gagatgggaa atgcacgaaa tatgggattt
    34321 accgaacttg tcagacgcct agctcaaaga aaacaattaa tgatcagaaa atacgaagat
    34381 gatcttttac agcttgctca gttaaggaat gcgatcgtcc atgatcggat cgcagtcgat
    34441 tttgtcattg cagagccaaa tgattggaca gtcaagcgaa tccagctgat cgaacaagaa
    34501 ctgattcagc ctgaaaccgt gctgcctcga tttgcaaaac gtgtaacagg ttttgaacaa
    34561 gatcttccgt tacttgaact gttaaagata gtagcagaaa aaaggtattc acaatttccg
    34621 ttatacaata aaggaaaatt tgtagcattg attactttac gtaatatcgg gttttggcta
    34681 gcaaaagaaa gccaaaaagg tccggttgat ttaacaaata aacgagcgtt ggatttgatc
    34741 atccaaaacg gaaagtacac aaattatcat tttgttccag ctaaaacaca tatttacgag
    34801 gttgaagcga tgtttcgtga gcaagggact ttggaagccg tacttatcac taaagatggg
    34861 aatcccgatg gtaatctgct cgggatcgta cgacctcgtg atatttataa acaaatagaa
    34921 aaggattgat tttttgttaa ttatttattg gatattcagc gctttgctag taggagtgga
    34981 tcagttggtc aaatggtgga tcactgataa tctagcgctt ggagagacga aaaatcttat
    35041 accaggtatt ttgtcactga atcatattcg aaacactgga gccgcatgga gtatgctaga
    35101 agggaagatg tggttcttta ctatagtgac actcattgca gtcgttgtga ttctcacatt
    35161 gatgattaaa aatcgtgaaa aaggtaatcg ctggttcatg attggattga gtttgattct
    35221 agctggtgcg attggcaatt ttatcgaccg tattcgtctt ggctatgtag tagatatgtt
    35281 ccagacagat tttatgagct ttccgatttt taacgtagca gatgtgacac ttgtatgtgg
    35341 agtgatttgt atgttaattt atattatttt agatgaaaag gatcaaagaa aaaaatgaca
    35401 gaacttaaaa cgacgattca ccatgaatct ggtaggatcg ataaagtatt gactaattta
    35461 ttcaccgatt acagtcgttc gcaaattcag ctgtggctga aaaatggagc ggtttctgtc
    35521 aatggacagc cagtcaaagc aaattacaaa gtaaaacaag gagacgagat tactgtcttg
    35581 atccccgaac cagaaacatt agatgtggtc ccagaaaata tcccgttgac gatcgtttac
    35641 gaagatgaag atgtagcggt gataaacaaa cctcaaggaa tggtcgttca tccttcagca
    35701 ggtcatacgc atggcacaat ggtcaatgcg ctgatgtacc atatcaagga tctttctacg
    35761 atcaacggcg ttattcgtcc aggtattgtt caccgaatcg acaaagatac ttccggactg
    35821 ctaatggttg ccaaaaatga ccaggcacac gaatcattag ctcagcaatt aaaagataag
    35881 acctctttgc gcaaatatgt tgctttagtc catggagaga ttcctcacga aaaaggaacc
    35941 atcaatgcgc caatcggccg ttcgaaggaa aaccggaaaa tgcaggcgat aagagaagat
    36001 gggaagtcgg ctgtcacaca ttttactgta ttggaacgtt tcgaaggatt tactctggtt
    36061 gaattaaaac tagaaaccgg aagaacacac cagatccgtg tgcatatgaa gtatatcggt
    36121 tatccgttag ctggagatcc agtatacgga ccgaagaaaa ctttgaaagg caatggtcag
    36181 tttctccatg cgcaaatgtt aggttttacg cacccgacta caaacgaaaa gatgatcttt
    36241 gaagcacctc ttccagaagt ttttgaaaaa actttagaaa aattaagaaa aaacattgca
    36301 ttttaattta gataacggta tagtaattaa caacgaaagc ataaaactta atagaattcc
    36361 tttaagttta gtcccgtgag gctaagaagg gtgggagcaa ggatacgtat ggtgcgccat
    36421 aagtagattg ctcattgaca tagtatagct atcagtgtat cagtatacgc tcagtctaaa
    36481 cattcctcct gtcctcttag ggcaggagtt tttttatgca aaaaagtagg gggaatgaaa
    36541 atgcaagcaa aagaagtagt agatcaggta accatgaagc gagcattgac tcgaattact
    36601 tatgagatta tcgagagaaa ccatagtatc caagatatcg tattggtagg tatcaaaaca
    36661 cgaggaatct acattgcatc aagaattgcc gaacgcctga agcagctaga ggatatcgat
    36721 attcctgtag gagaactgga tatcacttta taccgagatg acaaaaaaga aaatccagaa
    36781 gaaccggaac ttcattcttc tgacatccca gtttccttag aaggaaaaga agttattttg
    36841 attgatgatg ttttgtatac aggacgaacg attcgagcag caatggacgc agtaatggat
    36901 tttggcagac caagaaaaat ttcattagca gtcctggtcg atcgtgggca tcgagaattg
    36961 ccaatccgtg cagattatgt tgggaagaac attccaacat ctcgggcgga agagatttta
    37021 gtagagatgc aagagcttga tggacaagat cgcatcatga ttttgaaaga ggaagattag
    37081 aggagagaga aacatgtcgg agaaaaaagg atttcataat gatgacgtgg tgttagatat
    37141 ccacgatcgc ccaaccccag gacattgggt aggattaagt ttacaacact tgttcacgat
    37201 gttcggagca accgtgttag tccccatctt agtaggtatc gatccaggta ttgcgctagt
    37261 cagttcagga ctaggtacat tggtgtactt atttactact aaaggaaaga tacctgcgta
    37321 cttaggaagc agcttcgctt tcattgcagc gatgcagctt ttgatgaaaa cagatggtta
    37381 tccagcgatt gcacaaggag cagtcacaac tggattagtc tatttgattg ttgcgctgat
    37441 catcaaaaag atcggttcag catggctgga taaaatcttg cctccaatcg tcgtcggtcc
    37501 agtcatcatg gttatcgggt tgggacttgc ggcaaatgca gcaacaaatg ctatgtataa
    37561 tcagggcacg tatgatttca agtatattgc tgtagcgctg atcacattag gattaacaat
    37621 tttcttcaac atgtggctaa gaggttttct cggattgatt ccgattttac taggtattat
    37681 tagcggatac atcgtagcct tgctgtttgg aatcgtggat actaagccaa tcgtagacgc
    37741 tgcctggttt gctgttccta actttgagat tccctttgta caatatgaac caaagctata
    37801 tcttggagca atcacaacaa tggcacccat cgcttttgtg acgatgacag agcatatcgg
    37861 ccatcttatg gtattgaata aactaactaa acgtaatttc tttgaagaac cgggtcttca
    37921 taagacgttg acaggtgatg gattagcaca aatcgtggca gcctttgtcg gaggtcctcc
    37981 tgtaacaagt tacggtgaaa acattggtgt tctggctatc acacgtgtcc atagcgtgtt
    38041 tgtgatcggt ggagctgcag tatttgcagt cattttagga ttcgtaggaa aattaagcgc
    38101 tttgatttta agtatccctg gaccagtcat ctcaggaatc agttttatct tatttggagt
    38161 aattgccgca agtggaatga agattttaat cgagaacaaa atcgattttg ataaaaagaa
    38221 aaatctgttg attgcttcag ttatcttagt agtaggaatt ggcggactcg tctttgaagt
    38281 aggcacattt acattgtcgg caatggcatt agcaactgta cttggcatca ttttaaatct
    38341 tatcttacca gaaacttcac gaagcgaaga aaactaagga ggaaacatta tgatcatcaa
    38401 atcagaacgt atcagcttaa agcatttatt gaccgttgag gcacttactg atcaagaagt
    38461 tatgggcttg atccgcagag ggcaggaatt caagcaaggt gctaattgga ctccgcaaaa
    38521 gcgccagtac tttgctacaa acctcttttt cgaaaatagt actcgcacac ataaaagctt
    38581 cgatgtagcg gagaaaaaac tagggctaga agtgattgaa tttgaagcaa gcacaagctc
    38641 tgtccaaaaa ggggaaacac tatacgatac agtactgacg atgtcagcat taggcgtaga
    38701 cgtagcggtt atccgtcatg gtgatgagaa ctattatgac gaactgatac aaagtaaaac
    38761 aatccagtgt tcgattatca atggaggaga cggaagcgga cagcatccaa cccaatgctt
    38821 gcttgatttg atgaccattt atgaagaatt tggtcatttt gaaggtctga aagttgccat
    38881 cgtaggtgat atcactcact ctcgcgtagc taaatccaat atgcagatgt taaaacgtct
    38941 aggcgcacaa gtattcttct caggtcctag agaatggtac gacgatgaat tcgaagtgta
    39001 cggacattat atgccattgg atgaactact agatcaagtt gatgtcatga tgatgcttcg
    39061 ggtgcaacac gaacgccatg atggaaaaga aagtttctca aaagaaggct accatcagga
    39121 acatgggtta acagttgagc gtgcgaagaa gttgcaaaaa catgcaatca ttatgcaccc
    39181 agcaccagtt aaccgtgatg tagaattagc tgattcatta gtggaaggat tacagtcgcg
    39241 gatcgttcag caaatgagca atggagtatt cgtcagaatg gcaatcttag aagcagtgct
    39301 aaatggaaaa gcgtaattat aggaggatga aaaaatgaaa acactcatta aaaacggtca
    39361 gatcaataca cgaaaaaata tgacgacacc agcagaaatt tggatagaag atgggcgaat
    39421 caaagcaatc ggtacaggat tctcagaagc cgaatttgat gaagtgtttg atgcaaaggg
    39481 acaattgatc acacctggtt tagtggacgt ccatgttcat ttgagagagc caggatttac
    39541 atacaaggag acgatcgaag ctgggactcg ctcagctgct cgtggcggtt tcactactgt
    39601 atgcgcgatg ccgaatttaa atcctgtacc tgatacggca gaaaagctga gacaagtata
    39661 tgacatcatt agaaaagatg cagttgtgaa ggtattgcag tatgcgccaa tcacagaaaa
    39721 tctgcgaagt gagaaattag ttgatcaaga agcactgatt gaagaaggtg cttttgcttt
    39781 cacaaatgac ggtgtaggtg tccaaacagc tgggacgatg tatctggcta tgaaagaagc
    39841 tgcaaaaaac aataaagccc tagtagccca tacagaagat gaatctttat tatttggcgg
    39901 cgttatgcac gctggcaaga aggcagaaga acttggtctt cccgggatct taagcgtaac
    39961 cgagtcttct caaattgcta gagatctgtt gctagctgaa gcaactggtg ttcattacca
    40021 tgtttgccat gtttctacta aagaaagtgt ccgtgtaatc agagacgcaa aaaaagcagg
    40081 aatccacgta acagcagaag tttcacccca tcatcttatt ttgatcgacg aagatattcc
    40141 cgaagatttc ggcttttgga aaatgaaccc gccgctaaga ggacgggagg acagagaagc
    40201 tttgatcgaa ggcttgcttg acggtacgat cgattgcatc gctacagacc atgcccccca
    40261 tggattagaa gaaaaaagcc aaagtttcat gaaatcacca tttggtatcg taggaagcga
    40321 aacagcgttt caactgatct atactcattt tgtagaaact ggtcgattca cgttggaaca
    40381 agtgatcaat tggttggcag ttaaaccggc tgagattttt ggtttgaatg caggaacgct
    40441 aacggttggt gcccccgctg atgtagcagt ttttgatatt acacaaactt gcacgatcga
    40501 taaagaagac tttttatcaa aaggggagaa tacacctttt atcggctgga aagtaaaagg
    40561 cgaaacacaa atgacttttg tcaacggaaa acttgtgtgg cagaagggag aataaaagta
    40621 tggaacgttt gcttatatta gaagatggaa cagttttcga aggaaaggct tttggtgcag
    40681 atgctagtgt cttcggagaa atcgttttta caacaagtat gactggttat caagaaacta
    40741 tcactgatca aagttttaac ggtcaaatca ttacatttac ctatcctatg gtgggtaatt
    40801 atggggtaaa tagagatgat tatgaatcga tttctccaac atgcaaagga gtagtagtaa
    40861 aagaacatgc acgtgtagct tcaaactggc gaaaccaaat gacgctagat tcatttttga
    40921 aacaaaaagg aattcctgga atatcaggta tcgatacgcg cgcccttact cgcaaaatcc
    40981 gtgaagtcgg aacgatgaaa gctagtatag ttgatgctgg agattccttc gaacatgcat
    41041 ttgatcagct gaaagcaacc gttctagcaa ccaatcaagt gcagcaagtc tcaactaaca
    41101 aaccttatcc aagtccagga acaggtcgga aagtcattgt cattgacttc ggcttgaaac
    41161 atagtatttt acgagaattg agtaaaagaa actgtaacct cacagtactt ccctataaca
    41221 cagatgccga gacgatttta gcgctatcac cagacggagt catgctgacg aatggacctg
    41281 gtgatccaaa agatgtgcca gaagcaatcg aaatgatcaa aaaaatccaa ggaaaagtac
    41341 cgatttttgg tatttgtctc ggtcaccagt tatttgcttt agccaacggt gcagatacct
    41401 ataaaatgaa attcggacat cgaggattaa atcacccggt acgagaagta gcgaccggaa
    41461 gaattgattt tacttctcaa aatcatggct atgcagtcga tgaagccacg attgatccag
    41521 aaaaactcat cgtaactcat gtagaagtaa atgacggaac agtagaagga gtcaaacaca
    41581 gagattatcc cgctttcagt gtgcagtttc atccagatgc tgcccctggt ccgcatgatg
    41641 cactacattt atttgatgaa tttatggaaa tgatggacgc aggaaaggag cagtaaacag
    41701 atgccgaaac gtacagatat caagaaaatt atggtgattg gatctggtcc gatcatcatt
    41761 ggtcaagccg cagaatttga ctacgcagga acacaagcct gccttgcctt aaaagaagaa
    41821 ggatatgaag tggttttagt aaattctaat cctgcgacga tcatgacgga taaagaagtg
    41881 gcagatcaag tatatatcga accgatcaca cttgaatttg tatcaaggat tcttcgaaaa
    41941 gagcgtccag atgctctcct tccaacttta ggcggacaga caggcctcaa tatggcaatg
    42001 gagctggcag catcaggtat tttagaagaa ttgaacatag aacttctagg aacaaagctt
    42061 tctgcgatcg atcaagcaga agatcgtgat ctattcaaac agttgatgaa agaattgaat
    42121 cagccaatcc ccgagtctga aatcgtcaat acagtagaag aagctgtaga ttttgcaaat
    42181 aaaatcggct atcctgtcat cgttcgtcca gcctttactt taggcggaac tggtggaggt
    42241 atgtgtgaaa atgaagaaga attacgtatc gtatcagaaa atggattaag tctttccccc
    42301 gctacccaat gtttgattga acgaagtatt gcaggtttta aagaaattga atatgaagtg
    42361 atgagagatt cggctgataa tgcaatcgtt gtctgcaata tggaaaattt tgacccggtg
    42421 ggtatccata caggtgattc tatcgtattt gcccctagtc aaacattgtc tgaccatgaa
    42481 tatcaaatgc ttcgtgatgc ttctctttcg attattcgag cacttaagat cgagggaggc
    42541 tgtaatgtcc aactcgctct tgatccacat agttttaatt attatgtgat tgaagtcaat
    42601 ccgcgtgttt ctcgttcatc tgcgttagca agtaaggcga ctggctatcc gatcgctaag
    42661 ctagctgcta aaatagcgct tggattaaca ttagacgaaa tgaaaaatcc tgttacagga
    42721 acgacttttg cagaatttga acctgcatta gattatgttg tagctaaaat tcctcgctgg
    42781 ccgtttgata agtttgaaaa cggagaacgg cttttaggca cgcagatgaa agcaactggt
    42841 gaagtgatgg ctatcggtcg gaatatcgaa gagtctttat tgaaagctgt gcgttcttta
    42901 gaaatcggta cacaccatat cgaacttcct gagttggcag acatcacgga cgatgaccta
    42961 atccaaaaag tggttcgagc acaagatgat cgcctgtttt atgtagctga agctattaga
    43021 agagggtaca ccatagaaga attagcggat ttgacaaaaa tcgatttatt ctttttagat
    43081 aaactgttgc atatcgtaga aatcgaacag cagttgaaac agcagccgtt ggatgacaag
    43141 atattgaaaa cagcgaaaca aaacggtttt acagacaaaa aagtggcgga gctgtgggaa
    43201 ataaacgaag aagccgttcg ccagatgaga aaagaaaatg atttgattcc tgtatataag
    43261 atggttgaca cttgtgcagc ggaattcgaa tcaaaaacac cttattttta tagttcctat
    43321 gaatatgaaa atgaaagttc acgatcagaa aagccctcaa ttctagtact gggatctggt
    43381 cctatccgta tcggacaagg ggttgaattt gactatgcga ctgtgcattc tgtcaaagca
    43441 atccagcagg caggatacga agcaatcatc atgaacagca atcctgaaac agtttcgact
    43501 gacttttcta tttcggataa attatatttt gagccattga ccttcgaaga tgtgatgaat
    43561 gtgatcgagc tagaacagcc gataggagta atcgttcaat ttggtggtca gacagcaatc
    43621 aacttagccg aacctttgac tgctgctggt gtaaaaatct tagggacaac gatcgaagac
    43681 ttggatcgtg cggaaaatcg tgatttattc gagcaagcgc tgaaagagtt ggatattcct
    43741 caacctttag gggatactgc tacaagtaaa gaagaagccg tggttatcgc ttcgagaatt
    43801 ggttatccag ttcttgttcg tccaagctat gtattaggcg gacgtgcgat ggaaatcgtt
    43861 gaaaaccagc gagatttaga agattacatg gaacatgctg tgaaagcatc tccagaacat
    43921 ccagtactag tggaccgtta cttgcttggt ggtgaatgcg aagtggatgc gatttgtgac
    43981 ggtgaaacag tactcatccc agggatcatg gagcatattg agcgtgctgg tgtccattca
    44041 ggggattcaa tggctgtgta tccacctcaa acattatctg aatcgatcaa gaaaacgatc
    44101 gaagattaca cgatccgctt agcattaggt ttgaattgtg tcgggatgat gaatatccag
    44161 tttgtcatcc atgaaaatga ggtttatgta atcgaagtca atcctcgagc aagtcggact
    44221 gttccattct taagtaaggt gacaggaatt ccaatggcac aaattgcgac gaaagctatt
    44281 ttgggagaga aactaaagac acttggttat gaaaacggac tttatccaga aacaaaagaa
    44341 gtttatgtta aagcacctgt cttttctttt acgaaattgc agaaagttga tacttactta
    44401 gggcctgaaa tgaaatcgac tggagaagta atgggatctg acagacaatt agacaaagct
    44461 ttgtacaagg cattcgaagc ttctggatta cacttgcctg aatatggagc cgtattattt
    44521 acgattgcgg acgaaacaaa agaagaagca ctagaattag ctaaacgttt tacagaaatt
    44581 ggctatagtc tgataggaac gaaacataca gctgcttatt tcgaaaaaaa tggtctggtc
    44641 gttgaaacag tagcgaaaat ttctgaggaa gcagcagaaa aaaatgtagt cgacttaata
    44701 agagatggta aaacacaagt ggttgtcaat acgattgata aagatcgggg aaatgcttct
    44761 aaagacggtt tcatcatccg aagagaagca gttgaacatg gtattccatt gtttacttct
    44821 ttagacacag cagatgcgat cgttcgagtg atggaatccc gtgctttttc aactaaccct
    44881 atttaacggc gagcacatgt taagacaaaa agacgaaaaa ccgttgcagg aggggacaga
    44941 tgaaacaaga aatgatggaa atcgttcagc aaaaacagct ggcaccaaag atttttgaaa
    45001 tgacattgaa aggtgatcta gtaaaagaaa tgcagcaacc aggacagttc ttgcatattc
    45061 tcgtgccgcg tgcagacttg ctattacgcc gaccgattag cttgaatcat atcgaccacg
    45121 aaacaaatac ttgccgtatc atttatcggg tggaaggtga ggggactaga gtcttctcta
    45181 ctctttctgc cggagaccat ttagatgtca tgggtccttt aggcaatggt tttgatttgt
    45241 ccaatcttca tacaggagac gaagtattta taatcggtgg aggaatcggt gtccctcctc
    45301 tatatgagtt atcaaaacag ttagtcgaaa aaggaattaa gccaacgcat tttttaggtt
    45361 ttgccacaca tgaagtcgtt tattatgaaa aagaatttaa tcgtctagga gaaacaagaa
    45421 tcgctactga cgatggaaca tacggtatgc acggaaatgt cggtaattta ttgttaggaa
    45481 cgaagacgga acctacagct gtttttgcat gtggttcaaa cgggttattg aagacagtgg
    45541 aacagctgtt ttcttcgcat caaaatgtcc agttatcatt agaatcccgc atggcatgtg
    45601 ggataggggc ttgctatgct tgcgtttgtc atacgccgga agatgaaaca ggaacaaaaa
    45661 gtgtgaaagt ttgtgacgaa ggaccgattt ttaaaatagg agaggtaatt atatgaatga
    45721 gaatccttta gcggtcaaac ttcctggcct agaattaaaa aatcctatca tgccggcaag
    45781 cggctgtttc ggttttggca aagaatacgg aaaatactat gatttgaatc agcttggatc
    45841 gatcatggtc aaggcaacga ctccaaatgc ccgctttggc aatcccacgc caagagtggc
    45901 ggaaacacca tctggcatgt tgaatgcaat tggtttgcaa aatcctggtc tagacgttgt
    45961 tatgcataaa cttcttccag aattagagga gtacaatgag ttacccatca tcgcaaatgt
    46021 tgctggtgct tgtgaagaag actatgtaga agtttgtagc aaaattggcg aagcaccaaa
    46081 tgtgaaagca atcgagctga acatttcttg cccaaatgtc aaacatggcg gaattgcttt
    46141 tggaacagat tctgatgttg cttttcaatt aacacaagca gtaaagaaag tttcttctgt
    46201 tcctgtctat gtcaaattgt ccccaaatgt aacagacatc gttccaatcg ctcaggcaat
    46261 cgaagctgga ggggcagatg ggtttacgat gatcaatact cttcttggta tgcggattga
    46321 ccttaagaca agaaaaccga ttttagccaa tcaaacaggt ggactctccg gaccagcaat
    46381 caagcctgtc gctattcgtt tgattcacca agtagcaagt atatccagcc ttccaatcat
    46441 tgggatgggc ggcgtgcaga cagtggatga tgttcttgag atgtttatgg ctggagcaag
    46501 tgctgtagct atagggaccg cgaatttcac cgatccgtat atctgtccta aactaattaa
    46561 agagctccct gtgcgaatga gcgaactagg catcgaatcg ctggaaagat taatcaaaga
    46621 agtgagagag gaacgtgaac gatgaatcaa ctagaccaac gaccaattat tgcattagat
    46681 ttttcaacta ggcaagaggt agaagacttt cttcgatttt tcccgaaaga agaaaaattg
    46741 tttgtgaaaa tcggaatgga attgttctac caagaaggac ctgaaatcgt acgttatcta
    46801 aaagaggctg gtcataatgt atttttagat ctgaaacttc acgatattcc gaatacggtc
    46861 gaaaaagcaa tgcggggatt ggcaaagctt ggtgttgatc tcacctgtgt tcatgccgct
    46921 ggcggtattc gtatgatgga ggcggcaatg cgaggattag aagaggggac tccagaaggt
    46981 ggaaaacgtc cgctacttct agctatcact cagcttactt ctacaagtga agaagaaatg
    47041 catgccgatc aactaatcga agtttcttta gaaaaaagtg tgatccatta tgctagctgt
    47101 gccaaaaaag caggattaga tggtgtggtt tcttctgctt gggaagtaga agcgatcaaa
    47161 gaaatggcag gagacgaatt tgtttgctta actccgggta taagaccaga aggaacagtc
    47221 gcaggagatc agacaagagt agtcacacct tctcaggcaa aaaagatcgg ctcaactttt
    47281 atcgttatag gtcgaccaat cactcagtca actaatcctt ataaagcata tcaaacgatt
    47341 caaacagaat ggagctaacc taaaatgaat gttgaacaaa gtatcgcaaa agacttatta
    47401 gaaattgaag cagtattttt aaatccaagt aatcctttta catgggcaag tggaatcaaa
    47461 agcccaattt actgtgataa ccgaatcacg atgagctatc caaaagtccg aaaagagatc
    47521 gcaaaaggat tagcaagcaa aatcaaagaa gcttaccctg aagtacaagt gattgctgga
    47581 actgcaacag caggaatccc tcatgccgca tgggtagcgg aaatactgga tttgccaatg
    47641 gtctatattc gaagtaaggc gaaagatcat gggaaaggta accaaatcga aggacgtata
    47701 tttgaaggtc agaagatggt tgtgatcgag gatttgattt ctacaggcgg aagtgtcttg
    47761 gaagcagctg aagcagcaaa aagagaaggt gcggatatcc ttggtgttgc ggctatcttt
    47821 acgtatgagt tgccaaaagg aaaagcaaat ttcgaaaaag ccgaaatccc tcttatgacg
    47881 ttgaccaatt attctgtatt gattgaagca gctttagaag atcgttatat cgatgagcaa
    47941 gaattaactc tgctaaaaga atggaaaaaa gatcctgaaa attggcagat ttaagcgcgc
    48001 ttgatgaaga tagagaaatc cgatttgtgt ctccagaatc atcaattgga atagcaaaaa
    48061 tccaaaaact gattgcgaga agcatctttt catcaggtat gaaaagaaac ttctatcgtg
    48121 atcagttttt gattttttta aaattcattt ttctaagact ggttagcaga aagaagagaa
    48181 taatctcttc tcttttttct attatatata gattttctct attttttggt aagggagctg
    48241 tttcaaaaat ggtaaagagc ggaaatgttg cgaatatcag ttatttaatg atatgatatt
    48301 cggaaaaaga aatctcaaag ggaggtaact tttatggggt tgaatgaatt tattttagga
    48361 ttgaacaatt tagagacgat cacaagggca cctggatttt ttaaatatac agagcataca
    48421 gttgcagcac attcgtatcg tgtagcatct attgcgcaag ttctaggaga cattgaagaa
    48481 gcgaatggac aaccgatcga ttggaaactg ctctatgaaa aatcattgaa tcatgactac
    48541 acagagcgtt ttattggtga tatcaaaacg ccggtgaaat acgcaagcaa agagttaaga
    48601 gggatgctgc aaacagttga agaaaagatg acggacgaat tcatcaacca agagattcca
    48661 gctgagttcc aagaagttta tcgccgtcgg ttgttcgaag gaaaagatga aaccgtagaa
    48721 ggagaactat tagccatttc agataaggtt gaccttcttt atgaatcttt tgatgaaatc
    48781 atcaaaaata acccggaaaa agtttataag gagatgttca ttgaggcagt gactacgatt
    48841 aaaagctttg aacatcggcc ttctgttcag tatttcttta aagagatatt tccggaacta
    48901 ttgaaccagg aattttatgg aaaagaggcg tttttagaaa ccgtctcaac gattgtaaag
    48961 aaagaagaaa aataaaaatg atatgagatg cagggggaag tatagttgaa aaagaatatg
    49021 gatgtcgaat ggggctattc tggagacaaa ggtccggaaa attgggcgag tttatgtgat
    49081 tggtttgcga gaggtgcgga atttccattg cagtcgccta ttcatttgac caagggggaa
    49141 gaaaccaaaa tagaaggaga cacgctttcc tttcattatc aaaagcaacg gtttactgac
    49201 aaggaattca aaaacacgat tcatttagta ccttttgacc aactcagtta tgtagagttc
    49261 aagaaagaac gctattattt gacagatatt catttccact tgccttctga acatatcatc
    49321 aacggaaaac aggaagatat tgaatttcat tttgttcata tgaacagcaa aaaagagaat
    49381 ctagttgtgg gtgtcatgta ccagctaatg gtacaggaag gttggctgta taatcaagaa
    49441 aatggggaaa gttggaactt agaaaaacat gagcattggg taaatccgga tgtgttcttt
    49501 ccggagcaaa aaagccattt ccattatatt ggctcattga caactccgcc taccagcggg
    49561 ccaatccaat ggtttgtaat ggatcatgta ggaaaactga accaagagtt tcttctcccc
    49621 ttcgatggtc agtatgctcg accgaacaac cgaccaatcc agcccttgaa tggaagagaa
    49681 atttattatt tcgaggagtt tgagcaatga atattcagca gatgaaatac gtggtcgctg
    49741 tagcaaacaa tggtagtttc agagaagcgg caaagaaaat gtttgtctcc cagccaagtc
    49801 tttcagctgg tatcaaagaa ttagaaaccg agttagggat cacgctgttt actcgaacga
    49861 atcgaggggc atatttaaca gaagaagggc aagacttctt aaatcgtgcc gagaaaatat
    49921 tggtccagct tgatacatta gaaactcact atctaacgag tgaaaagaga gacaattttt
    49981 cgatcgctgc ccagcattat gatttcttag gtcctttgac cgcacagcta ctcgaggaat
    50041 tcaaagacga gatcaaacaa tttcggatca tggagacgac aacagcgaga gtgatcgaag
    50101 aagtcaaaga gcagcacagt gagatcggca ttatttatat gaatgagcat aatcaagctg
    50161 gtatcagaag atatttacaa caaggagagc taagtggccg cagcattgga aaattcaaaa
    50221 cgcatatttt tttaaggcaa ggacatccat tagctgaaca cgcagagatc accaaagaag
    50281 aattgttatc ttatcctcaa gttcgtttta cacaggatgg aaataatttc ccgtattttt
    50341 atgaagacct tatcgagatc cctgatcaag aaacagtgat ttatacgagt gatcgaggta
    50401 ctttgatgaa tatcgttctt gaaactgatg cttacgcttc aggatctggt attgtgattg
    50461 gagggattcg cgagcacttg cggttaatcc ctttggcaga aggcgaacta aatgaatttt
    50521 atatcattta ttcggcgaaa cgtccgctca gtgaaatcgc tcaaagattt atcaaagagc
    50581 ttactcggtt actggaccag cagagctaag aaaagcagat gagaacgctg tttattgaac
    50641 accgttgatc aaaaaagagg ggttgtgaca gaattttgtc acaactcctc tttttgtagc
    50701 aaacaattta taactaattg ctgttgtggg aaagtacgca aatatgattc tagaaacact
    50761 cattgattac ctgttttgtt tcatagctgt aattttttct tcttctggtg tcacgataat
    50821 cgtcttttgg ttttcataaa taacataacc aggcttggcg ccatttggtt ttcggatatg
    50881 ctttacctgt acaagatcaa ccggcacttg ggcagagtat cggtattttg aaaaataggc
    50941 agctaactcg gcagcttctg taattgtttc atctgagggc ttgtcacttt taatgatgac
    51001 gtgcgaaccg ggtatatttt ttgcatgaag ccaatagtcg gtttttttag ctgtcttcat
    51061 tgtcagctgg tcattttgaa gattgttttt accaacaaga atgagcgttc cgtcagaaga
    51121 aaagtattga tcaggctgag atggtttctt acgtttttgt ttttttaagt tcttcttttt
    51181 caggtatcct tctgaagtca attcttcttt aattgcttcg atatccattg ggccggcaat
    51241 ttccagttga gataagacag attcaagata ttggatttca tctttggctt cttggatttg
    51301 ttcgccaatc agcttaacag cgttcttcag cttttggtat cgatggaaat atttctgtgc
    51361 attttgattt ggtgtcaatg ccggatctag tgctattttg attggccgat cttcttcata
    51421 ataattaggt aaaacaactt cttttgcgcc gcgtggtact tgtgtcagaa aagtagtaag
    51481 tagttcgcca tttctacggt aattctcagc gttttcggat tctttgagtg tttgttcacg
    51541 ttttttcaat ttatttttat ttcgttttag ttcattttcg atttttcgaa tcagttctcc
    51601 gccttgttgt tttgcccgat ctttctctgc tttttcgtga taatagctat ctaataattg
    51661 actgagtgtt ggataagctg ttacagcaga tgcctgttcg gacaatacct gataagcaat
    51721 cggtgtgaaa aaatctttat tttccgtttc gtaaaaagta ggaataggct gatggctgat
    51781 ggctgagaaa aattcgtccc atacaaccat cttttcatta ggacgttcca gtaatctttt
    51841 ggtcagctct tgagcgatat cgaaaccgat tccctgaaac tgacgttgga ttgcttttgg
    51901 atctagttca gtttgggaaa gccgctgaaa gattttttct ttctcggagc taaatgggtt
    51961 caagacctct tgttttggcg gagcaacata ttctacacca ggaagcaaag aacgataagt
    52021 gttttgagag cttccaatgt gtttgatcgc atccagtatt tttccagttt ctcgattaac
    52081 taagacgatc gtactatgac gtcccattaa ttcaacgatc aatatgatat tttgtagatc
    52141 acccaactcg tttcgtttag caaagtggaa atggatcact cgatcatttt cgatttgttc
    52201 gatgtcttct aaaatagcgc catccaaata ttttcgaagc atcatcacga agttaggcgg
    52261 attatcagga ttctgataat cgatttgggt aatctgtaca cgagcataac ttgggtgcgc
    52321 agataataat aatcgatggt ttttgccgcg tgaacgaatc accagcacga tttcattttc
    52381 ataaggctga tggattttcg agatccggcc agatagtaac gtttcacgca attcgttgac
    52441 catcgcgtgg gtaaatacac catcaaagga catggttcat tcctcatttc ttttcataag
    52501 tatattcatt ataacgaaaa aaagaagaaa aaccaatttg gccgaatagt aaagcaaaag
    52561 tctagaaaaa tcttggacta attacataaa aaacagtgtt tctatcgttg aaatccaaat
    52621 ttttaggta
//
LOCUS       DAFEKH010000018        52433 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.019, whole genome shotgun sequence.
ACCESSION   DAFEKH010000018
VERSION     DAFEKH010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 52433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52433
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.019"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..705)
                     /locus_tag="LP386_001130"
     CDS             complement(<1..705)
                     /locus_tag="LP386_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBL1918380.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKELKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFI"
     gene            1393..1551
                     /locus_tag="LP386_001131"
     CDS             1393..1551
                     /locus_tag="LP386_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1918381.1"
                     /translation="MNKKQTCEFLGIDNNTLDKWIRIYNFPVIRIDGIVRFDIEDIKD
                     FMNTFKTI"
     gene            1623..2843
                     /locus_tag="LP386_001132"
     CDS             1623..2843
                     /locus_tag="LP386_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL1918382.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFREITGITSEKYQKVFPTRQLAIKA
                     ENAMKRKIETVLREENANSLELKGKIKFKEFYESKWLPRYELGQTTRSKRAPSYVTIS
                     NTKDIFRLHILPMFGEYAMNYLNSNTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQCITAPKKIALEERRIREGNQALSSEELIAWIEAVNTDLNNHLL
                     TLHDYTLFMLTLYLGDRKSETYALQWKYIDFEKQTVRLKHALDKYQKKKFTKGRKDTV
                     IQVPEIVMALLSKWKSVQAEQLLRLKINQTPDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPELAHLSPHKLRHTYATIARQGGANMNQISNALTHSDISTTKIYVNTPDVV
                     DKTVFEAFQKGLKN"
     gene            complement(2936..3328)
                     /gene="rpsI"
                     /locus_tag="LP386_001133"
     CDS             complement(2936..3328)
                     /gene="rpsI"
                     /locus_tag="LP386_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBL1918383.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(3344..3787)
                     /gene="rplM"
                     /locus_tag="LP386_001134"
     CDS             complement(3344..3787)
                     /gene="rplM"
                     /locus_tag="LP386_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HBL1918384.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(4306..4773)
                     /locus_tag="LP386_001135"
     CDS             complement(4306..4773)
                     /locus_tag="LP386_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HBL1918385.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(4893..6431)
                     /locus_tag="LP386_001136"
     CDS             complement(4893..6431)
                     /locus_tag="LP386_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HBL1918386.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            6511..7197
                     /locus_tag="LP386_001137"
     CDS             6511..7197
                     /locus_tag="LP386_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBL1918387.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(7398..7925)
                     /gene="msrA"
                     /locus_tag="LP386_001138"
     CDS             complement(7398..7925)
                     /gene="msrA"
                     /locus_tag="LP386_001138"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBL1918388.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(8009..8686)
                     /gene="pgmB"
                     /locus_tag="LP386_001139"
     CDS             complement(8009..8686)
                     /gene="pgmB"
                     /locus_tag="LP386_001139"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBL1918389.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(8683..9813)
                     /locus_tag="LP386_001140"
     CDS             complement(8683..9813)
                     /locus_tag="LP386_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBL1918390.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(9813..11996)
                     /locus_tag="LP386_001141"
     CDS             complement(9813..11996)
                     /locus_tag="LP386_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBL1918391.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIAPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(11993..13018)
                     /locus_tag="LP386_001142"
     CDS             complement(11993..13018)
                     /locus_tag="LP386_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL1918392.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(13063..13890)
                     /locus_tag="LP386_001143"
     CDS             complement(13063..13890)
                     /locus_tag="LP386_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBL1918393.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(13887..14954)
                     /locus_tag="LP386_001144"
     CDS             complement(13887..14954)
                     /locus_tag="LP386_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HBL1918394.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKHGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLIGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(14980..15816)
                     /locus_tag="LP386_001145"
     CDS             complement(14980..15816)
                     /locus_tag="LP386_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL1918395.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(15813..16682)
                     /locus_tag="LP386_001146"
     CDS             complement(15813..16682)
                     /locus_tag="LP386_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1918396.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(16752..18035)
                     /locus_tag="LP386_001147"
     CDS             complement(16752..18035)
                     /locus_tag="LP386_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBL1918397.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(18049..19734)
                     /locus_tag="LP386_001148"
     CDS             complement(18049..19734)
                     /locus_tag="LP386_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HBL1918398.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            20009..21034
                     /locus_tag="LP386_001149"
     CDS             20009..21034
                     /locus_tag="LP386_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1918399.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(21629..25303)
                     /gene="rpoC"
                     /locus_tag="LP386_001150"
     CDS             complement(21629..25303)
                     /gene="rpoC"
                     /locus_tag="LP386_001150"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HBL1918400.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAEMKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(25361..28978)
                     /gene="rpoB"
                     /locus_tag="LP386_001151"
     CDS             complement(25361..28978)
                     /gene="rpoB"
                     /locus_tag="LP386_001151"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBL1918401.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            29706..30674
                     /locus_tag="LP386_001152"
     CDS             29706..30674
                     /locus_tag="LP386_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL1918402.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            30692..31597
                     /locus_tag="LP386_001153"
     CDS             30692..31597
                     /locus_tag="LP386_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1918403.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            31594..32400
                     /locus_tag="LP386_001154"
     CDS             31594..32400
                     /locus_tag="LP386_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1918404.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            32536..33525
                     /locus_tag="LP386_001155"
     CDS             32536..33525
                     /locus_tag="LP386_001155"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HBL1918405.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(33842..34366)
                     /locus_tag="LP386_001156"
     CDS             complement(33842..34366)
                     /locus_tag="LP386_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HBL1918406.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            34653..36464
                     /gene="scm"
                     /locus_tag="LP386_001157"
     CDS             34653..36464
                     /gene="scm"
                     /locus_tag="LP386_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HBL1918407.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDT
                     SASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTS
                     ASSDSTDTSTTTSDSTDTSASSDSTDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSS
                     TTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKR
                     ALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
     gene            complement(36619..37605)
                     /locus_tag="LP386_001158"
     CDS             complement(36619..37605)
                     /locus_tag="LP386_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBL1918408.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(37628..38194)
                     /locus_tag="LP386_001159"
     CDS             complement(37628..38194)
                     /locus_tag="LP386_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HBL1918409.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(38208..38624)
                     /locus_tag="LP386_001160"
     CDS             complement(38208..38624)
                     /locus_tag="LP386_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBL1918410.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(39081..41015)
                     /locus_tag="LP386_001161"
     CDS             complement(39081..41015)
                     /locus_tag="LP386_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBL1918411.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            41296..42252
                     /locus_tag="LP386_001162"
     CDS             41296..42252
                     /locus_tag="LP386_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HBL1918412.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            42342..43445
                     /locus_tag="LP386_001163"
     CDS             42342..43445
                     /locus_tag="LP386_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBL1918413.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            43458..44411
                     /gene="menA"
                     /locus_tag="LP386_001164"
     CDS             43458..44411
                     /gene="menA"
                     /locus_tag="LP386_001164"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HBL1918414.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFDLVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(45225..46571)
                     /gene="gor"
                     /locus_tag="LP386_001165"
     CDS             complement(45225..46571)
                     /gene="gor"
                     /locus_tag="LP386_001165"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HBL1918415.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(46705..47958)
                     /locus_tag="LP386_001166"
     CDS             complement(46705..47958)
                     /locus_tag="LP386_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBL1918416.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(47964..48887)
                     /locus_tag="LP386_001167"
     CDS             complement(47964..48887)
                     /locus_tag="LP386_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBL1918417.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(49108..51600)
                     /locus_tag="LP386_001168"
     CDS             complement(49108..51600)
                     /locus_tag="LP386_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBL1918418.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(51607..52074)
                     /locus_tag="LP386_001169"
     CDS             complement(51607..52074)
                     /locus_tag="LP386_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HBL1918419.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(52210..52283)
                     /locus_tag="LP386_001170"
     tRNA            complement(52210..52283)
                     /locus_tag="LP386_001170"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(52247..52249),aa:Arg,seq:acg)
     gene            complement(52341..52414)
                     /locus_tag="LP386_001171"
     tRNA            complement(52341..52414)
                     /locus_tag="LP386_001171"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(52378..52380),aa:Pro,seq:tgg)
BASE COUNT        15219 a        11063 c         9585 g        16566 t
ORIGIN      
        1 aataaatata gtatctccat aggctttttt taaattctct tcattaaata cagattctac
       61 acttccgtga gcaattagat ttcgattcaa aagaataata ttatcaaaat acttctttac
      121 cttgcttaaa tcatgatgca caattagcac tgtttttccc tgatgtttca attcttttaa
      181 cgtatccata attattcgtt cactaactaa gtctatccct acaaatggtt catctaaaaa
      241 tatgaaatcc gcattttgag caagacatct tgctaaaagt acacgttgaa attgtcctcc
      301 agataattct cctatttgat gattagaata ttttcccata tcgacctttt ccaaagcctt
      361 tgaaactctt tgccattctg catttttaat tctttgaaaa actttcattc cggcatatgt
      421 tcccatagat acacattctt ttacttttat tggaaaagta aaatcaatat cagctttttg
      481 ctctacatat gcaatcttca ccagtttttt attgatatct tcattattaa tggagacctc
      541 tccctgatga gggataatat ttaacattgc tttaagcaat gtagattttc cagcaccatt
      601 tggaccaata atacctgtta aagcaccttc ttgtattttt aaagaaatct cgttcaatgc
      661 taaaaaatcg ttataacaaa cattaagctt tttcacttct aacataactt tctccttcta
      721 aatgataatg attatcacga tcatatggta tacaaaaatt atattttagt caaccctaaa
      781 ttttataatt tagatttttt tctgttgctg aagattagaa tgacaaaact atttgaaact
      841 acgcgtatag taagtagctt tcaaaatata taaaaaagga gcgttctcaa atgagaacat
      901 gctcctaaaa ctactttatt ggcgtatgga aaaattatac ttaaagtgga tagcgggttg
      961 aataagttga taagcatcaa aacatttata aaaattattc aagactatgt ctgttccata
     1021 tacaaatatg aaaatcagta aactccattt aacttttttc gtagtgtgtc tttttataca
     1081 tgtttatcgt tattaatagt gaataggaaa aaacctattt ttgatcattg acaattaaat
     1141 acaatttttg aataacgatc cctgctattc gagctagaaa ctcaagtacg ccatgacctg
     1201 attagcgaca aatacttaga gatttctttt tgttctggga aaacaaaatg ccatgacaat
     1261 agcagcaaat aatgatactt ccgtaaggct cgccgtaaac tggggagagg tgaaattcct
     1321 atgtgcttac ccaaagcaat tcaaaaattc taatcttttt taggagatga ttttataaaa
     1381 ttgagagtct acttgaataa aaaacaaacc tgtgagtttc taggaattga taataatact
     1441 ttagataagt ggattcgtat atataatttt ccagtaatca gaattgacgg tatagttcgc
     1501 tttgacatag aggatatcaa agattttatg aatacattta aaacaatttg aaaatttctt
     1561 ctcgccgcat atactaagaa tagcgaaata tactgcctta ctttttaagg gagtgaggaa
     1621 ttttgcctac aaaactttca aatgggaaat ataaaactaa tctgaggtat ccaaaaaaat
     1681 tcagagaaat cactggaatt acatcagaaa agtatcaaaa agtatttcca actaggcaat
     1741 tggctattaa agccgaaaat gcaatgaaaa ggaaaattga aacagtttta agagaggaga
     1801 atgcaaattc actagaatta aaaggaaaaa taaaatttaa ggaattctat gaatcaaaat
     1861 ggcttcctag atatgaacta ggtcagacta ctagatcaaa aagagctcca agttacgtaa
     1921 caattagtaa tactaaagat atattccgat tgcacatcct tccaatgttt ggtgagtatg
     1981 caatgaacta tctaaattca aatactgaga taatatcaga tgaattaaca aaaaaatcga
     2041 aagaatacgc aaatataaaa attatcaaag gatatgtccg ttctatgttt gatattgcag
     2101 aaatactaaa ttatattgaa tttaaccgaa ctaccaaaat tattcaatgt atcactgcac
     2161 ctaaaaaaat tgctttagaa gaaagaagga tacgggaagg taatcaagca ttatcgtcag
     2221 aagagcttat tgcttggata gaagcagtaa acactgactt gaataatcac ttgcttactc
     2281 ttcatgacta tactcttttc atgcttaccc tatatcttgg tgatagaaaa agtgagacgt
     2341 atgctttgca atggaaatat atcgactttg agaaacaaac ggttcgcctt aaacatgctt
     2401 tggataaata tcaaaaaaag aaatttacaa aaggtcgaaa ggataccgta attcaagtac
     2461 ccgaaattgt aatggcatta ctaagcaaat ggaaatcagt gcaagctgag caattgttga
     2521 gattaaaaat taatcaaaca ccagatcagt atctctttac ctatactaaa ccatccggag
     2581 aagtaaattg ccctgttcac gctgattacc taaactatcg aatcaattca attaaaagac
     2641 gacatcctga attggctcat ttatctccac ataagcttcg tcatacctat gcaactatag
     2701 ctagacaagg cggagcaaat atgaatcaaa tatctaatgc tttaacacac tcagatattt
     2761 ctactacaaa gatatacgta aacacaccag atgtagttga taagactgtt ttcgaagcat
     2821 ttcaaaaagg attaaagaac taggatgaat gtgttctcga atgtgttctt aaactaaaaa
     2881 aagacacttt ccaaataatt gaaaagtgtc ttgaaacatt gatatacaaa gaatattaac
     2941 gttttgaaaa ctgtgaagct ttacgagctt ttttaagacc tggtttttta cgttcgacca
     3001 tacgtgcgtc acgagtaagt aagccagcac gtttaagagc taaacggaag tcaggatcaa
     3061 cttctagcaa tgcacgagcg ataccatgac ggatagctcc tgattgtcca gcgtatcctc
     3121 cgccgtttac gttaacaaat acgtcatatg cgccttttgt ttcagtaaca gcgaaaggtt
     3181 gattgattac ttcacgcaag tcagcatgtg gaatgtattc ttcaacatct tttttattta
     3241 cagtaatttt gccagttcct ggtactagac gtacgcgagc aactgcgttt ttacgacggc
     3301 ctgtgccgat atattgaact tgtgccaatg aaattccctc ctattagatt aagtttgtga
     3361 tgtctaaaac ttctggttgt tgtgctgcat gtggatgttc tgctccaccg tatacgttca
     3421 attttgtaaa ttgtttgcgg cctaaagtgt ttttaggaag catacctttt acagaagttt
     3481 cgatcaaacg acgagaattt ttagcacgca attcgccagc agtgattgat ttcaatcctc
     3541 ctgggtagtt gctgtgacgg taataaattt tgtcagtcgc ttttttacct gttaatttca
     3601 ctttgtctgc attgatgacg atgacgaaat cgccagtatc caaatgaggt gtgaaagttg
     3661 gtttattttt accacgtagt acagatgcaa caactgttga aagacgtccc aatggaacat
     3721 cagttgcgtc tactacatac catttacgtt ctacttcgcc tggtttggcc atatatgttg
     3781 tacgcacgtt attttcctcc aatttaagtt ctgatgtttg acatacactt cgagtttccg
     3841 gggctctttg tggggcaaac aataccattt aacatattac ccgctaatct agtcaatgtc
     3901 aacgtttttc tgcttgattg aaaaatttat atgaaacttt acttcttttc tttcttttat
     3961 ataaaagggt cgtttcctgt caaaatgaaa aacaaaaaga ggctgtgaca aaagtcttgt
     4021 cacaacccct tattttgaat aaacggtgtt ctcctgccaa ctcctcggtc acaagtcaca
     4081 atatccataa aacataagaa gctgtttttt aaaattgttt cttgtgactc ggagctgaac
     4141 ggcaggctta caacctcttg gtaaacggtg ttcaatcagc tgaccctcgg tattagctca
     4201 aaaaacggca aaatatgagg aactattttg acgtttgttt ctctaatact caggtcaaaa
     4261 cgctgatttc acaacctctt tttcggtcaa gttcaacaac agtttttacg cgtcgatctc
     4321 tggcgctttg cccaaatgag cttggatcat ccagatacgt ttttctgtgg ctgttttgaa
     4381 ttcgataaag atatcttgtg ttggatcgtc gccttcttct ccagaaactt cgattccttt
     4441 ttggtaaaga tctgctagat aacgatagcc tgcaacaagt gtttccaaac gttctggaat
     4501 agtacgatcc cagcggccaa tttcatcagg gatttttgtg ttatctgcaa attcacgcaa
     4561 tgtagaataa ggtgaaccgt ctaatgtgat caagcgttcg gatacttcat ctaactgagc
     4621 gttcaaatca tccatgaact catccatcat tgggtgcaat gtaaggaaac ctggtcctct
     4681 catgtaccaa tgtgtttggt gaacaacaac agacatttgg cttagatctg caactaattg
     4741 atttaatact tctttggttt gttggaattt catctttctt gcctcctaac attttcttac
     4801 acttaaaata atagtagact ttcaatgaaa agtacaacaa aatcatttac ctgagaacga
     4861 ttttcagttc gcttttttat ccgtaaagcc aatcattttt cagaatcagc taattcttct
     4921 cgcagttgag caaattgctg ataagtctgt gctaaatgct tttgtgtcga aacaaataat
     4981 ggatagattt tctgatattt tttatgatca gtttcttgta ctccaacttg ctctttcaat
     5041 tctatcaatt cctgtgcttc actgatactt tggatctttc cgatgcttct ccagcctaaa
     5101 atcacagctc ctaatgcgga tgcttctgtg acagtaggga aaacaagcgg gtaacccagt
     5161 acatcagcca tcatctgacg aaaaatcgga gattgagcaa acccgcctgt agcacggatc
     5221 tctgtgagct gattttcctg gcaaactcct tttaaaatcc gataaaggtt gagacagatc
     5281 ccttctagaa tcgccttcat catttctttt tctgtatgtt gccgctgtaa accgataaaa
     5341 ctgccaaacg catctgcgtc ccaaagcggt gctcgctcac caagtaaata gggatgaaaa
     5401 atcagaccat tggcacccgc tggcacaaaa gcgatagccg aaagcagtgc atcatatgga
     5461 ttttctcctt tttctttagc agattgaacg acttcctgta aaaatgtatg ccctgcccaa
     5521 tcaaagatgc cagcaccatt gctagtcgct cctcccacta cccaatgttt ctgatccaga
     5581 acataacaaa acgtctccat ttctggatgg aactgaggct gagtagtaat aaaacgaagt
     5641 gctccgctcg ttcctacggt caaagcggcg atcgtatcac caaaagcacc taaccctaga
     5701 ttagaaagcg gcccgtctgc ccctcccaaa acaaatgata tatcatttgg caaacctagt
     5761 tctgctgctg tttttgatgg tagacctgtt acttgatagg tggaaggaaa gacttgcggc
     5821 aattgctcta ttcgaatgtt caagtagtca agcacttctt ctgcccattg gaattcatgg
     5881 atatcaaaat atccagttcc tgaagctgtt ccgtagtcgc tgatcagttc gccaaacaat
     5941 ctataaaaga tatagtcttt gataccgaca aaataagcag tttttttgaa taattcaggt
     6001 tggctgtttt gcagccactt gattttgttc aatggtgtca ttggatgaat cggcgtccca
     6061 gtctgccgat aaaattcttt gccaagcacg gtatatttca gtttttctgc ttcgtccgct
     6121 gctcggttat ctgcccaagt gatcattcga gataacggtg ttttctcttc atccaacaat
     6181 atcaggccat gcatcgcaga ggagaaggag acaaattgaa tgattgtgtc tgaaggcaac
     6241 tgtttaatta cttcttttat aacggtgcag acaccttgaa agatcaattc ctgatcttgt
     6301 tctgccatcc cttgtgtttc ttggatcaaa gggtagcgaa aataagcgga tgctgcttct
     6361 tgggcttcat ctgtgaaagc aactgctttg gtttgtgtgg ttccgatatc taatccgatt
     6421 gaaacgttca ttttttcacc tcaaatttta tgtatgtaca aaaatttagt ttaagcttgc
     6481 gtatcttggt tttgaaaagg gggagatggc gtgttacttt attttatcat tggttgctgt
     6541 atcggatcat ttttatgttt aaccgcccag cggattccgt taggtcactc tattatttat
     6601 cctagatctc attgtgtcaa atgctgtcgt tcgctttctt ggtatgaatt gattccgatt
     6661 ctctcgatca tcgtccaacg atttcgctgc cgctattgca ggtgtcggtt gcccttctac
     6721 tatttgttgg cagaagcctt atgtggtggt ctttttgcct ggttctttac tttttcttcc
     6781 gcaagaaatt tttcgacgtt catatggatg ctttcggctt tgctattttc gttgatggat
     6841 ttattttact tcatggtcca ttctcacacg ctattctgtt cttgggcaat tttatggatt
     6901 ttttggttgc aggccggcgt cttccaatgg caaagtgtgc tgttaacgtt tatcgtaggc
     6961 ggtgtgtgcc ttcgctatgg tcaatcctat ctcggagctg gcgatactct gttgatgctt
     7021 tcttggagtg gtggcttgtc tctagaagag ttgcttcaga tcttgtttct tgctagtctg
     7081 tttggaatat ccgttttttc tgtttacttt atctgtcata aaaaaaagtt ggaaaagctg
     7141 cctttcattc cttttttgag cagtgcgttg ctgattgtcc ttcatcttag gtattgaaaa
     7201 aaggttgtga caaacgactt gtcacaacct ctgatatata gtgttctctt accaaatcct
     7261 tgtgacttgg agctaggcga caggttcaca acctctccac taaatggtgt tcaatcagct
     7321 gaccctcagt attagctcaa aatgctggtt ttacaacctc tgatatacgg tgttccataa
     7381 gtagcttttt cggcttctta tttcttgacg ccccaatgtc gacgaaggaa acctgcacgt
     7441 ccagaacctt ctcgataaag attgtaatgg agcttgtttt tcttgtaata atcctgatgg
     7501 taatcttctg caggataaaa ttcgcttctt ggttcgattt ttgtcacgat tggcttatcg
     7561 aatcgcccgc tgtcttgcaa tgcttgtttt gaacgctctg caatatttcg ttcttcttca
     7621 tcattatagt agatcactgg acgataagaa tcaccgcgat cagcgaactg tcctaatgcg
     7681 tcagtcggat cggtttgctg ccaatagatt tccaccaact gatcataaga aataacttct
     7741 ggatcatatt cgatctctac tgcttctgta tgccctgttg tgcctgttgt tacttgttca
     7801 taagttggat ttggtacatg cccgccagta taaccggatg tcacagaaat gatccctggc
     7861 tgctcttcaa atggtttgac catacaccaa aagcatccgc ctgcgaaaac tgcttttttt
     7921 gtcatataaa atcccccttt tttctcatca taccttgatt tccaaaagga ggataacgtt
     7981 ttgcttgtga cagaaaaaac ggaaactatt atatacgtga tacggcttct gataaatgcc
     8041 aaaacgaacg tacttgatca aaaacggtta aatcaggaat cacatattca gcagaaggaa
     8101 gatttatgtt ttcacctatt cccaatacat gcatgttacc agccaaagct gcttgacaac
     8161 cagcttctga atcttcaatg accaagcatg catttggcgg tacattcaat tgctgtgctc
     8221 ctttgagaaa aacttctgga tcaggttttg cttttgatac ttgcgtgccg tcaataagga
     8281 catcaaaata acttgtcaaa ttcgtttttt ctaaaatgag gcgtgcattt ttgcttgctg
     8341 atcccaatcc gatcttgatg tttgtttttt tcaagtactc aagaacagct attgcaccag
     8401 gcaaaacgga tgtttcatcc attttttgaa tcgcttgaag atatagattg tttttttgct
     8461 cagcaaaggc tgatttctct ttttctgaga atttctgttc catttttcca aatgacagca
     8521 atcgctctag tgactcggtt ctggatattc ctttcagttg ctcgttttct ttctcagtga
     8581 atggaatgga cagctggtta gctaaaacca gccacgcttc gtaatgataa cgagctgtgt
     8641 ctacaagaac gccatctaaa tcgaatagtg ctgctttgat tttcatcgat tacctccttg
     8701 aaaatgaacg acttgaagta aagatgcgat gtttttagct gtgcgatgaa gattatcagt
     8761 ggcttgctgt aaagcttctt gtaaaggcac agctgcagga aggatcggaa aaacggccga
     8821 aatgccaaca tctgctgctt tttcgcttcc tttaccaaca cttccgcaaa tagctatcac
     8881 aggaacgccc tctggtactc ttctagcaat cccaactggc gcttttcctt ttagactttg
     8941 tccatctaga cgtccttcgc ctacgattac gaggtctgct tgctgtaccc gtttatcgaa
     9001 ctccagtaaa tccaatacgt agtcgatgcc agagactatt ttccctgaag caaatgctaa
     9061 cagtcctgca cccattccac caccagcact actgcccgat gcctcgatta cttgaggggc
     9121 aaatctcata taaaaatcat gcatggcttg gtcagccact gctaattcat tttctttcaa
     9181 gcctttttgt ggtccgaaaa caaaagaagc gccttctttt ccgcataaaa gattagtaac
     9241 atcagtaatg acagtgattt tggctttaat cagctcaata ggcacgttcg ttttatcaac
     9301 tgtagcaatt ttacctagat tttctcccag tgcttctact ttttgattat cttgatcgta
     9361 aaaagcataa cctagacctt ctgccatgcc gatgccgcca tcgttggtac tacttccgcc
     9421 aacgccgatg atgatgtgtc gaacaccttg ttgcaacaat tgtcgtatca gttctcctac
     9481 tcctcgcgtg gataacctaa gtggctgttg ttggtttagt gggacatctt tcaatccgac
     9541 gatttctgcc atttcaaaaa tcgcagtttg accgtctgaa gcgtactgga tttctttgtt
     9601 tttgccaaat gcattagtaa cgactgctgt ttgccgcttc aaccttaaac tgtctgctaa
     9661 tgatgaaacc gttccttctc ctccatcgcc tataggtagc agatcatatt cagcctgaac
     9721 aaaaacttct tgaaaacctg attgaatggc ttgtgctgcc tctaaggctg tcagactttc
     9781 tttgaaagaa tctggcgcaa tcagaatacg cattattttc ccctccgttc caagatcagt
     9841 tctttttcca gctggtattg gtctccattg acaaaaatag gtaatgtttc tttcgtctct
     9901 ttttttatta ctatttgttt ttttgtcaaa acaaatagca acctgtgatt tttccaaata
     9961 aaaggaaaag aaattttttc ccatgctgaa ggaagtcttg gagaaataga aagagttcca
    10021 ttcgttactg taatacctga aaaaccaaat ataactgcta gccatagtgc tcctaatgaa
    10081 gcagcatgaa ttccgtcatc tgatgaatgc ggatctggtc ctaaatcaat caggcacgct
    10141 tcttggaata aatgatacgc ccattccatt tcttggatac ggcaagcctc tatggcgtga
    10201 atcgctttac tcaacgatga gtcgtggatt gttttgtttt catagtaatg caaattctta
    10261 gaaacgattg gttgagaaaa atactcaggt aataagtata acagcatgac aagatctgct
    10321 tgcttgctga cttggagttc atttacttcg ctacgggcat aatcaagtaa aatagactgg
    10381 ctgccaggac gttctttgta agtggtcaaa tcaataactg gcttactgag atacgtgtca
    10441 tcttgcggaa tcagctgttc tttgttaggc actggcaaat ataacttatc taaaaaattt
    10501 tgacattctt tcaaaaaaag cggatcgcca gcttgatatt taacagctaa ggccacatta
    10561 taatgcgcca gatagttcgt atatgcatta ttgtcgatat attctgtgta ttcatctgga
    10621 gcaatgactc tgtgtatctc taaatgatca tcgactttta cagctctgct cagccaaaaa
    10681 gctgctgttt catgaatgag cgtttttccc tttgtttcta aaaacgattg atcctctgtt
    10741 gcttggacat actcttgaac ggcataagca aggtctgcac tgatatgatg ttctgcggca
    10801 gctgaagcaa cttcttgtct tgttccggtt ttgatattca atgcagcaaa tttgggtgtc
    10861 tcttcctgac cagtgtgtgc gctttcccat gggaaaagtg caccttgata gtgataatct
    10921 cttgcttttt gccgtgcgcc ttctaatcga tcataacggt acagcagcaa attctttgct
    10981 acttcaggaa actgatataa aaagaaaggc aggataaaaa tttccgtatc ccagaaaaca
    11041 tgccctttat aaccttcgcc agttagtccc ttcgccccta cactaacact tggatcattg
    11101 cggggagtca taatctgtaa atggtaagca gcgaagtcca tcgctaactg atcgaaagaa
    11161 gaatcgcctt ggatcgttat ccgatgctga tgccaaaaat ctgtccaata agacatcgac
    11221 tgctctaaaa tttctgtata actaacgctt ttctgggctt gggcaatact tttcttaaac
    11281 gggtctgttt gctgaagaga ggtagagagc acgatgatct tctccagcgt aaaggacgta
    11341 ttttttctga tcttttctga aaaggaagcg gtgatccggc gattttttgc ttggaataca
    11401 cctgctttat tgaatttagc tgcaatccca atatcaattt tactttctgt tgtctggtag
    11461 gatgcactga tcaaatcgtc accaaatact cgcagttctt tttcaaccaa ctgctgtgta
    11521 ccaaaattgg tttgctgtcc atcgataccc gttttcacat ctacttggca gtcttcggtc
    11581 aacggcttga tgaccacttt cagggctgcc tgatggagat tattttgatc agcaacacga
    11641 caagtaatga cttccacttt ttttccttga gcagtttcaa tgagcgcata gcgtttaagc
    11701 tctcccattt ctaaatctag tgcccgctcg tatgcaagaa ctttcatcgt ctcaagagaa
    11761 aaatgttcac cgtcgatttt tatttcccat ctgatgacat ctgggagatt cactaactcg
    11821 gctgattctg ctcctaaagg tcggttatat acaccagctg caaacattcc ccttacttga
    11881 ttccgatagt cttcctcctg gcttcctctg ataccaaaaa atccatttcc aatggtcatc
    11941 tgactcgcat acttattgat atactctaaa tcaaactgtt tttcttctac tttcataagg
    12001 taataacttc tcctgtttct gccgaacgat ataaattttc caccagattc tggatgacat
    12061 atccttgcca gccatctgca atcatctgag tctggtcacc gagcgcccga ttcacaaaat
    12121 gagccatact tagttcatgt gggtcattaa ctggcgtggt cttttgtaag gaaaccagct
    12181 ttccatctac atcttcgaat agttcgcctg gatacagatt agcacctgcc tgatcgccac
    12241 aaaaagccac attcagtttg tcttctctga tattcaaagc aaacgaagta ttcagttgga
    12301 tgatcttgcc gttttctaat tccagtgtgc caaaaattgc atcttctact gtgaatttgc
    12361 ttggatccca tttcccgaat ttccctgaat tttttttcgt accaattttt tggaagctgt
    12421 acgcccgaac gctttttact ttaggaaatc cagtaatata catcgctgta tcaagcatgt
    12481 gaatgccata atcgatcaaa ggcccgcctc cttgaagttc tttgtcgata aacgttcccc
    12541 agcctggaac accagaccga cgaagcgcat tcgcttctac gtaataaata tccccgagaa
    12601 catcaagatg attcttgatc attgttgctt cgtcagaaaa acgatgctgg aatccataag
    12661 ccaaaatctg cccgttttta tcggctgtct ctgccatctt tcttgcttga tcagctgtca
    12721 tagctggtgg tttctcgcac atcactgaag cattagcttc gagggcagcc aatacatgtt
    12781 cgaagtgaaa gcgattgggt gtacagacac tcacgatatc gggagaaatc tcattcagca
    12841 tttgtgtaac tgatgtatac gcatgagaaa atcctgtacg tcggcaaaag tcttctgctc
    12901 gctggctgac tggatcaacc acagcggcca attctaagac atctgatctt ttttgataat
    12961 aagcagcatg tactttttct gctacttgtc cagcgcctat gattgctact ttcttcattt
    13021 atttctctct cctttgctta tttacttatt gttattcttt ctctattctt tctctaaatc
    13081 atttaaatga cgcgctgttt ccagacagtt tttcaagtat tgcaatgatt cctgataaat
    13141 tttcacttca ttttctcctc gcaaacgaca ttcatatacc atataacctt catactcatt
    13201 ttgaagtagc gtttgaaaat ggcgagtaaa atcaattgcg ccagatcctg gttggtagcg
    13261 atgattatct gctaaatgga tatgacccac atactctttt tgcgtagtca atgcttttga
    13321 aatatcatct tcttcaatat tcatatgata aaaatcagcg atgatctgca catgtttcaa
    13381 ttgattagag tcaatgtaat gacgcgcatc cgctaacaaa ttgatcatat ggtcttggta
    13441 tcggttcaaa ggctccaaat aaataaccgt acctgtttct tcggctactt tatctaaata
    13501 acgaagtgat tcgctgactg ctttatagtc tccttctttg cttcggggtg aaaccatcgg
    13561 cggtaatcga taagtgaaca ttccccaagc tgctgggata acgattcctt tgcctccaac
    13621 ctcgcttagt gcacgcaaaa tctcagcaat ttgacgtaca ccattaagac gccgttcttc
    13681 gataaagtca ccgatccacc catcgtagcc gttacaagct gtcactactg ggatccctgt
    13741 ttctttgatt gcctgtttga ctgtgtcgat attttctatt aacaacttac cgtcgatttc
    13801 gtattcttca aatccacagt ctttgataaa tctaaatttt tctaaaatgt ctcttgggaa
    13861 aaatgcttga tcttgcgtac cgaatttcat tgttctcctc ctcggacttg aacgcccatt
    13921 ttgatacttt cttctgggtg ctggtctaca taacgcatgt aagcttctgc gctttctgca
    13981 aatggcacaa ctggatcaat gatttcttca caatccaagt aaccgttcat caataattcc
    14041 caacatgtgt cctcgattcg tttacggttc catcttgggt aatctgggtt tggttcacta
    14101 gatgctcgag caaagacgat ttttgcatta ttgaaatgtg cttcgcgacc aagattaaac
    14161 ccagctggaa aaggtttagc aaaggcaaca taagaaatga tcccgccata gccgatccct
    14221 attaaagaag cttgtaatgc ggcagcactg ccactcgttt caataactga atctactcca
    14281 cgtttatctg tcaattcctt tagacgaaaa ccgacatctg ctttcatagg atctagcgtg
    14341 taatcggcac cgtgtttttc tgctaattct ctacgctgcg ctatgggatc gatcccaacg
    14401 atggtagtag cacctgcttt tttagctaat tgaatcgcaa tttgcccgat agcgcctaaa
    14461 ccgaagattg ctacagcatc acctgctcga acatgtgctt cccggatacc acctaaagcg
    14521 aattgagcag gatcgtaaca tactgcattt ttccattgat ccaaccgatc aagtttacgt
    14581 agtttataat tatcaacacc gtttgtaatc agcgtttcac gaatgggtcc ataagtgcag
    14641 actaactctc ctttttgata ctctgtcacc aaactgcccg tttcttcgat cgtaccgaca
    14701 atcatatttc ctaattgaaa ttcgccaaat accacaccgc gttggcttcc ttcttctctt
    14761 ggcaagaata ggcgccattc ttctgaaaat tcttcatcga taaatggact taatcctcta
    14821 aagtcgacaa tttctgttcc tggttttgga gtagcgaaaa ttactcggat acgtacttcg
    14881 ttcttttcga tctcacggtc ttcgtaatct ttgaatccgg ctattcttgg ttctaatgca
    14941 actaattttt tcatcttttc tttcctcttt cttttctttt tatcctttta cgccgccttc
    15001 gactaaatca cctttaataa atcgttcaga taacgcatac ataatgatga ctggtaaagc
    15061 ggtcaccaat gaagcggcca tcattcgtcc ccaaatgtag tctggtgtac tgaataatgt
    15121 gttcaaaccg attggtaaag taaatttttc ggaggtcgac aggaaaatcg aagcaaataa
    15181 ataatcattc cacgaaacca taaagcaata aacgaagaca gaaatgattc cagaaatagc
    15241 caatggtata atgatccgaa taatgatctg gatccggcta agaccatcga tcattgctgc
    15301 ttcttcaata tcagtcggaa tcgtgtcaaa ataacttttt agcatgaata tcgcagtagg
    15361 aagtgtttga acgaccatcg tgataatcag tgctgtattg gtatcataca aacctagacc
    15421 ggaaatgatt ttaaataatg gaacaacgat caaaataccg gaaaacatat aaacggtgta
    15481 aaagctagca ttgattttcg agcgagcttt gaagcgtagt tttgacaaag cgtatgcccc
    15541 gctgatccca atcactactg cagttacgga ggctatcaag gagatcacta aactattttt
    15601 gaaatacatg atgaatggaa aaatctcagc attgaaaata tcctgataat gttcaaaagt
    15661 ccattctttc ggaaaaatag tttgtgtcgt tgcaattgct tcttgtgaat ccttgaatga
    15721 tgtcatcagc atgatcaaaa atggaaacaa attgacagct aatagcaaca aaatcgtcgc
    15781 gtaaaataag attttcctgc tctttttatt tttcatttca agtccacctt ctttcgtgag
    15841 agcaagacga ccgctgcaat aatgatgaac aatagaatcg atatagctgc tgcttttcca
    15901 agatcattga acgcaaaggc tgtctgatac aaataaacgc ctaagatatt gactttattc
    15961 gtcagtagat agacatctgt aaacatatag aacatccaga tagatcgtaa aacaatcaca
    16021 gttgctagta ctggtttgat tgccggcagt gtcacgatct tgaacttctg ccaagcattt
    16081 gcaccgtcca tttcagctgc ttcataaagc gttttgtcga ctgtttgcaa aatagccaaa
    16141 aatgaaataa acgcatacgg atagtatctc cagatagcaa acaaaacgac cataaagaag
    16201 ctagcaactg gctggtcgaa ccacagcggt gcttcgttga aaagctgcaa cctatctact
    16261 aacagatcat tgacgattcc ataactatta ttgaacatat atttccaagc aaaaatcaaa
    16321 gaaatagatg gcgtaacata acttaataaa atcagtgaac gcaccgtttt cctaaatctg
    16381 aacttgcggt taagcaaaat agctacggct aatcctaaag ctgtactgcc tgctacaact
    16441 aagaatgtgt aagcaactgt taaacctaaa gaacgataaa attcactatc acttaaaatt
    16501 tcaagataat tgcttaatcc gataaaaacg gcgtctgagt taggattcag cggcatatcg
    16561 aaaaaactga tctgaatatt ggaaagcatt ggaatcagca ctaaaacagc taataaaagc
    16621 atgcttggtg ctaaaagtcc catggctaat tttaagtcag aatgtttcct tggacgattc
    16681 attgaaacct ccccctgata atctgccaat agctatctac ttttttcgaa caccattggc
    16741 agaacttctt gttatttcgt atttttttgt gcgtcagcta aagcttgatc gacatcttcg
    16801 tttccgacag ttacttggtt cactgctttt ccgatcacac ctgagcttgt gatatctccc
    16861 attttcgtga aattcttttc cccgactagt ccaaagactt gtacttcatc aaaagcacta
    16921 gcaatctcag atggcagctc gccaaaagac ttgatgactt cattttcttt gtaaccatcc
    16981 agttcgacta cttgtttatt cactggttga gcaccaccag gagacatcaa gacccacttt
    17041 tccatgtttt tcggttgaga taagaaagct gtgaatgctt cagcagcctc tttttgtttc
    17101 tcgtctagac cagaagaaat cgtcaatcca gatactgtgc catagacagc ttgatctttt
    17161 tgtgttggga tagcaaaacc gatattttct gagttccccg cttcataaac agaaggcaaa
    17221 atgtaagttg aatagattgc cattggtgct gttccattca tgaaagcatc tttgatttct
    17281 gtcacatcat tagagcctgg catcgtgtat tgggataagt tttgataaaa cgacaatgct
    17341 tctctcatct tttccgtatc gatcgttacc tcgccttcat catccaaaac atttgctcca
    17401 tttgacaaag caaattgaga gaacgcttgc tcactcattg ttccttcagc agtaggcata
    17461 gcaattccat attgtttatt ctctttatct gtgaaatgtt gagcaatttt taaaatatca
    17521 tcccaatttt ctggttctga aaaaccagct tctgataatt tttctttgtc ataccaaata
    17581 ccttgaaccc agccgctaat tggtgcagca atatagcttt ttccatcttc tgaacgaaca
    17641 aggtttttgg ctccgtcata ataattatct tctccagctt cctcgataac gttttggact
    17701 gccgtctgat caatcagttc atctttatcc atcactttag caaaatcctg actgacttcc
    17761 attacttctg gtaatttacc ggaacgagct aacgtaacga tttttgtatt gaacgctgat
    17821 tcttctaccg gcacttgctt gattttgatg tctggatttt ctttttcaaa atcagcaacc
    17881 agttcattga tcacacttaa tcgttcctgt tcgacagaag agtgcatgaa ttgaatcgtt
    17941 gtctgttgtg attcgttaga gctttgactt tcaccacaag cagtaagaag aaatccagta
    18001 gctagcagac aggtagtaac aataattttt ttcatttttt tccacctctt attttattat
    18061 tttcagccac atatattcat acggctggaa tatcaacttt cgttcttgac tgcaatggat
    18121 aatttgtcca gaaaacaggt ctaggtaatc tccttttggt aaaagataac ctgctgattg
    18181 attggaaaaa ttatggataa ctaagacttt ctcttccttc gcttcgcgaa taaaactgat
    18241 aaaagaatct gctgagtcca gtaagtaaat caaactattc ggatggaagg ctttttcttt
    18301 ttttcgaata gatagcatct gggtcaattc accatatact gctgttctta atggatctgt
    18361 ctgcaactct ttctcaatat ctgctaacaa aaatttttgc cgattgattt ttcgattctc
    18421 tcctgttttt tctacgcctt tgtaatcatt tcgacttccc agcacacttt gaatataaat
    18481 tgccggcacg cctggtaacg ttaccaaaaa tgaatgagca gctaaaaagc gtttgcttct
    18541 ccattccgtc gtatctgttg gagaacttaa cgcatctaga tacgtagcgt ttatctcata
    18601 tggactggtc gttccatctg ggtttttctt gtagtttact cgggcaccct ctttcttcag
    18661 ctgttccact aattcaagga tcgttttttc cggcagaata cctcgtaccg gattcaatcc
    18721 gataccgtca tgggaggcta aaaaattaaa aaaagttgtt tttttcgatg cgaaatcgat
    18781 ggtttttaac cattctttca acttacttgt attacccgaa cgaatcgctt gaagggtcaa
    18841 aggtggtagc gaaaactgat agaccatctg tgcttcattc tcgccattcc caaaataact
    18901 gatattatct ttgtgtggca catttgtctc agtgatcaat accgttcctg gagctgcttc
    18961 atcagcgatt gcacggaata attggatgat tttatgcgtt tctggcaggt gtatacaaga
    19021 agttcctagt tctttccata aaaatcccac agcgtccaag cgaataaatg aagcgccttt
    19081 ttctaagtaa aacaaaagaa tatcgatcat tttcaataaa acttctggat ttttaaaatt
    19141 caagtctact tgatcttcgc taaaagtcgt ccatacgtgt ttttctttcc cgtttttgtc
    19201 aatgaacgtt gtaagtaacg ggctggtcct tggtctagtc acgctgcttg tatctgtatc
    19261 cagtggcaaa tcaataaaaa aatctttgta cgtatcattc aagtttaaat attcctgaaa
    19321 ccaagtactt tcggcagaca tatgattgca gacaaagtcg aacattaacc gtgtttcgct
    19381 tctcatttct tctatatctt cccatgtgcc caaacggtcg ttgattgcct gataatttac
    19441 aacggagaaa ccatcatcag atgtatatgg gaaaaatggc aagaaatgta caactctaaa
    19501 tgtatctgcc aaatactttt gataaaattt cttaaatgta cgcaaagttg gttgctgctc
    19561 ttcaaaaaat tgatccccat aagtaatcaa gaaaatatct tcttcgtccc aatgcagttt
    19621 gcctgcctgg cctttcttct gctgataaac actgactttt tgttcaatca tagaggcggt
    19681 tttctcagac aaatctgagt cgcgataaat cgcttgtaaa agttttgtat acatcggatt
    19741 cccctttctt ttttgggagc gttcccaacg atttgatcat attatggaaa acgcttactg
    19801 tcaatagcat ttttttaaat aattttgata tacacaaaaa tacaaataag aaagcttatg
    19861 tatcaataat taatagcttc ttaaaaaaat atggtctctc atgatcatgc aagctattcc
    19921 taaattttca aaatcataga caaaaaagaa tgtctattgt actatggaat tattctaaaa
    19981 cgctcccaaa aaggaggtgc atataaaatt gaaacctact atttatgaca ttgcgaaaaa
    20041 agctaatgtc tcaaaatcaa ctgtctccag agtattaaat aaccagccaa atatctctga
    20101 taaagcaaaa gcaagtgtac ttcaagcaat caaagaattg aattatgaac cgagcaaaat
    20161 tgcaagagga ctgtcaggaa atggttttga cgcgattcta gcattatctc atcgtacttc
    20221 tcatacgacc tatggcaatc cttttttttc agatgttatt caatccattt ctgccgtttc
    20281 tgaacaaaat aacttcgact tgattctaca aacggcaaaa acaccagaag aagagctaga
    20341 aaaatgcgcg aaaaagatcc aagaaaaaat gatccgagga attattattt taagctctac
    20401 gatggatgaa acacttcttt ttgaattgga tcaatacaat attcctattg tggtaatcgg
    20461 aaaagtcgga aacgactaca cgaacatcta ctcagtggac acggataatt tccaggatag
    20521 ttacgatttg gtggaaacac tgatcaagaa tggacaccgt catatcggct gtctccatgc
    20581 tccgacagaa gtttatgtat ccaatgatcg tctcaatggt taccgtcaat gcttatttga
    20641 tcaccaccta gatatccgta atgaatggat tatagacggc ggctttcgct tagaagatag
    20701 catggcagca atgaatgatt taatgaagct acgagaaaga ccaactgcga ttttttctac
    20761 cgatgcatta aaatcattga gtatttacaa agtggcagaa caatctggaa agcagatacc
    20821 tgatgatctt tcgatcgcag gattcagtga tcccttattg tcctccctat tttcgccaca
    20881 gttgactcgg atagacattc cgacaaatca gttaggaatc aaagccacag aacttttatt
    20941 ccaactaatc caccaccaat accctgaaga aaaaagaatc attctttcaa ccgagattac
    21001 tctcacagat tcgatccaac aacaagaaat gtagaacaga attataaaag aacagaaaca
    21061 ctgaggataa gtcagttact ctgttctttt ttcaatcact catccctcgt taccccctcc
    21121 cggtatttta gcgaattttt cttattttcc atctgtttta gatagctgtg gataactata
    21181 atgtttgtgt taaactattt tttccacagg gaagaaaaaa ctatttttaa ccacgttgtg
    21241 tataagtttt tatagttcgt ttttttaaac acatttaccc ttatttcaat ccatgttatt
    21301 tggggatact tatctctaaa acataaatag aataacagac atgtctactg gttttgtttt
    21361 attcgaggaa ttattcaata atagctagca aaatattaaa aataaccgct ctatcttccc
    21421 atcaatttat tttgcattca aaaaatgatc tatctttact tttgttgatt gacttctctt
    21481 ggaagatgat cgttccgata ccttaattgg atacgaaccg atgttgttaa gatcctttcc
    21541 cacttttctt ctagttagac aaattatttt agacaaacca aaaaagaggt tgtgacaata
    21601 atttgtcaca acctcttttt taaaatatct attttgtttg attgttcatt gcgtcttctg
    21661 cagccatttg cgcttcaata tctgaaatac tgtagacatt ttcgcttgct acaccgactt
    21721 cttttggttc catgtcacga taacgttgca taccagtacc agctgggatg atcttaccta
    21781 taataacatt ttctttcaaa ccaagaagag gatctttctt accgcggatc gcagcatccg
    21841 tcaagacacg agttgtttct tggaatgatg cagcagataa gaaactattt gtttctaatg
    21901 atgcttttgt gatacctagt aagacaggtc gagaagttgc aggaacgcct cctgagacta
    21961 gcgtattgta gttttgatct ttaaagtctg cgatgtctaa taatgtacct ggtaagatat
    22021 ctgtatcacc tggatccatt acacgaactt tacgcagcat ttgacgaacc attacttcga
    22081 tatgcttgtc gccgatttct accccttgca tacggtaaac acgttgtact tcacgaagca
    22141 agtagttttc aacagataat acatcgcgaa cttgcaacaa ttgttttgga tcgattgatc
    22201 cttctgtcaa tggtgcacca cggtggatca tatcgccttc tgctactttc atacgtgctg
    22261 tataaggaac agtatacgta cgtgtatctg tttttccttt gattgttact tctttggtac
    22321 gtgttgcagg atcttctgag atatcgatga catcccctgt tacttctgtg atcactgctt
    22381 gccctttcgg attacgtgct tcaaagattt cttggacacg aggaagacct tgagtgatat
    22441 cgtctccggc aaccccacct gtatggaatg tacgcatcgt caactgagta ccaggttcac
    22501 cgattgattg agcggcgatc gtaccaactg cttctccgac ttcaacgtca gagccagttg
    22561 caaggttgcg tccgtaacaa tgtttgcaga caccatgttt tgtattacat gtgaagacag
    22621 aacggattgt cactgtttcg acacctgcat caacgatttg ttttgcgatg tcttcggaaa
    22681 tcaattggtt tcctgcaatg atcaattcat ttgtttcagg atgacgtact tctttacggg
    22741 tgtaacgtcc cactaaacga tcttctaatg attcgatgat ttcatttccc tcgcggatgg
    22801 cttggatttc aagacctcgg tcagtaccgc aatcttcttc acggatgatt acatcttggg
    22861 ccacgtcaac cagacgacga gtcaagtaac ctgaatcggc agtcttcaag gctgtatcgg
    22921 tcatcccttt acgagccccg tgagttgaga taaacatttc caagacggat agtccttcac
    22981 ggaagttcga aatgattggc aattccatga ttcgaccatt aggagcggcc atcaaaccac
    23041 gcattccggc aagctgtgta aagttggaaa tgttaccacg agctccagaa tcagacatca
    23101 tgaagattgg atttttcgct tccaaacctt ccatcagttt ttgttggatg ctgtcttttg
    23161 cagcattcca aacagcaatg acacgttcat aacgttcgtc atctgtgatc agaccacgac
    23221 ggaattgttt tgtaatagtt tcaacttgtt tatgggcatt ttcaatgatt tcttgttttt
    23281 cattcagtac actgatgtca gcgatcccta ctgtgatacc ggcatgtgtc gaatgtttgt
    23341 accctaagtc tttcatacgg tcaagcatct tagaagtttc tgttactttg aatcgtttga
    23401 agacttctgc gatgatgttt cctaagtttt tcttcttgaa cggtaatact aattcttgct
    23461 ctttgatatg tgcaggaata tcagtaccag cttcaacaaa gtatttgtcc ggtgtttgga
    23521 cggtcaagtt gaagtctgtt ggttcattca gataagggaa ttcaggaggc atgatctcgt
    23581 tgaagatgat cttaccaact gttgtgatca tcgtacgttc tttttgccat tcagtaaatg
    23641 gtttttcacc taatgagtta gggttcacac cgatacgtga atgtaaatga acatatccgt
    23701 tgcgccatgc gataacggct tcgttttgat ctctgaagac cattccttcg ccttcgcgtc
    23761 cttcttcttc cattgtcaag tagtagttac ctagaaccat atcttgagaa ggagtaacaa
    23821 ctggtttacc atctttaggg ttcaagatgt tttgagcagc taacatcaac atacgtgctt
    23881 ctgcttgtgc ttcttcattc aatggaacgt ggacagccat ttggtctcca tcgaaatcgg
    23941 cattataagc ttcacataca agtggatgca aacggattgc gcgtccttgt actaaaactg
    24001 gttcgaatgc ttggatacca agtcggtgaa gcgtaggtgc ccggttcagc aatactgggt
    24061 gttccttgat tacgtcttct aaaacatccc atacttcgtc ttcttgacgt tcgattttac
    24121 gtttcgcatt tttgatgttt gaagctagtt cgcgttgaac aagctcacgc atcacgaatg
    24181 gtttgaataa ttcaatggcc atttcttttg gaagtccaca ttggtacatc ttcaagaaag
    24241 gtccaacaac gataacggaa cgacctgagt agtcgacacg tttacctagc aagttttgac
    24301 ggaaacgacc ttgtttccct ttcaacatat gagaaagaga tttcaatggg cggttacctg
    24361 gtccagtaac tggacgtccg cgacgaccgt tatcgatcaa tgcatctact gcttcttgca
    24421 gcatacgttt ttcattttga acgatgattc caggtgcatt caagtctaac aaacgtttca
    24481 aacggttatt acggttgatt acacgacggt aaagatcatt caagtcactt gttgcaaaac
    24541 gtccaccttc taattgaacc attgggcgta aatctggtgg aataacaggg ataacgtcca
    24601 taaccatcca gcttggttga tttcctgaag cgcggaatgc ttctaaaata tccaaacggc
    24661 ggattgcacg tgtacgtttt tgtccttgtg cagatttcaa ttcttctttc atttcggctg
    24721 cttctgcatc tagatcaaca ttatcaagta attgtttaat cgcttctgca cccatagcag
    24781 cttggaattc ttgtccatat tgttcacgtt tttcgcgata ttcgcgttct gtcaacaatt
    24841 gttttttctc taaattcgta tttcctggtt cgatgactac atatgaagca aaataaatga
    24901 tttcttccaa agcgcgtggg ctcatgtcta atacaagacc catacgtgaa ggaatccctt
    24961 taaagtacca gatatgtgaa acaggagctg ctaattcaat atgtcccatg cgttcacggc
    25021 gaactttcga acgagtaact tccactccgc atcgatcaca aacgattcct ttataacgga
    25081 tacgtttgta ttttccgcag gcacattccc agtcttttgt aggaccaaaa atccgctcac
    25141 agaacaaccc ttcgcgttca ggttttaagg tacgatagtt aatcgtctca ggttttttta
    25201 cttcaccgta agaccagctt ctgatttttt cgggagaagc caaacctatt tgcatacttt
    25261 cgaatttatt tacatcgatc aaaaggggtt ccctccattt catttaatgg caaaccgcaa
    25321 gacggctgat cttcgaccgc cttgcagctc atagaccgga ttagtctaaa ttatcttctg
    25381 cggtttcaaa gttttggatg acatcgtctt tttcatcttc cacttgttca gcagctttct
    25441 tttctaattc tttggcagtt tgctgttcgg caaattttgt caaagcatca acagtgatca
    25501 aatcgtcgtc ttcatcgtcc atgtcgcgaa gttcgatctc tgtttcttcg atatccaaga
    25561 cacgcatgtc cagacctagt gattgcaatt ctttcaccaa tacgcggaat gattccggta
    25621 cacctggttt tggaattggt tcacccttga cgattgcttc gtatgttttc acacgtccga
    25681 ctacgtcatc tgatttgtat gtcaagattt cttgtaaagt ataagccgca ccgtaagctt
    25741 ccagtgccca tacttccatt tcaccaaaac gttgtccacc aaattgagct ttacctccca
    25801 atggttgttg tgtaaccaat gagtaaggtc cgattgaacg tgcatgcaat ttgtcatcga
    25861 ccatgtgagc aagtttgatc atgtacatca caccgacaga cacacgtcca tcaaatggtt
    25921 cacctgtacg tccgtcgtac agaacagttt tcgcatcgct ggccataccg gcttcacgaa
    25981 ctgtttccca tacgtcttca tcacttgcac catcaaatac tggcgttgct acgtggatac
    26041 ctaactgacg tgcagccata cccaagtgta attccaatac ttgcccgatg ttcatacgtg
    26101 aaggcacccc taaaggattc agcatgatat cgattggtgt tccatcaggt aggaatggca
    26161 tatcttcttc cggcataata cgggatacaa cccctttatt tccgtgacga ccggccattt
    26221 tatccccttc atggatttta cgtttttgaa cgatataaac acgaactaac atgtttacgc
    26281 ctggtgacaa ttcatctcca gcttcacgag taaagatttt cacatcgtga acgataccgc
    26341 cgccgccatg tggtacacgt aatgatgtat cgcggacttc acgagctttt tcgccaaaga
    26401 tcgcatgcaa tagacgttct tctgcagata attctgttac cccttttggc gtgactttcc
    26461 ctacaagcaa atcgccatct tggacttctg caccaatacg gatgataccc atttcgtcta
    26521 aatcttttaa tgcgtcttcc ccgacattag ggatttcgcg tgtgatttct tcaggtccta
    26581 attttgtatc gcgggcttct gattcatatt cttcaatatg gatagaagtg tatacgtcat
    26641 cttttaccaa acgacggctc atgatgatcg catcttcata gttgtaccct tcccaagtca
    26701 tgaaaccaac taaaacgttt tggcctagag ccatttcgcc ttgttccata gatggtccgt
    26761 ctgccagagt atcccctttt tcgactttct cacccaaatg aacgattgga cgttggttgt
    26821 agcttgttcc ggagtttgaa cgacggaatt ttgttacatc gtatttatct aatgcaccgt
    26881 tgtcgcggcg tacgcggatt tcagaagcat caacgtattc aacgacaccg tcatgtttac
    26941 ataacaaagc agctcctgag tcatgcgctg atttgtattc cataccagta ccaacccatg
    27001 gtgcttgagg attgatcaac ggcactgctt gacgctgcat gttggcaccc atcaaggcac
    27061 ggttggagtc atcgttttcc aagaaaggaa tacatgctgt cgcaacggca actacttgtt
    27121 taggtgatac gtccatgtag tctactttat caatagatac ttctaagttt tcactttgag
    27181 cacgagccat aacaacgtct tgagcaaatg ttccatcttc attcaatggg ctgtttgctt
    27241 gggctacgat gtaatggtct tcgatatcag ctgtcaagta gtcgatttgg tcagtaacac
    27301 gacctgtttc acggtctaca cgacgataag gtgtttcgat aaatccgaat ttatttactt
    27361 tcgcataact ggacaaacta ttgatcaacc cgatgtttgg gccttcagga gtttcgatcg
    27421 gacacatacg gccatagtgg gagtagtgaa cgtcacgaac ttcataaccg gcgcggtcac
    27481 gagtcaatcc gccaggtcct aaggctgaaa gacgacgttt gtgtgtcaat tcgccaagag
    27541 ggtttgtttg atccatgaac tgtgacaact gagaagaacc aaagaattct ttgatacttg
    27601 ccacaactgg acggatattg atcaattgtt gaggtgtcaa tgtttcagta tcttggatcg
    27661 acattctttc acgaaccaca cgttccatac gtgctagccc gatacggaat tggttttgta
    27721 aaagttcacc gactgaacgg atacgacgat ttcctaagtg gtcgatatca tcgacattgc
    27781 cgataccttc catcaagttc aagaaatagc tcattgaagc aatgatgtcg gctggacgaa
    27841 ccgtttttac agctgcttct ggatagccgt ttccgatcac gtttacttca cgttcagggt
    27901 ctcttggtga aaatactttg atgacttgga cagtcattgg atctgtgacc acaccgtctt
    27961 ctgatggata gtaagtcact gaatttaggc cattatcaat gaaaggagct agtgtttcca
    28021 tgacttggtg agtcagaact gttccttttt caacgatgat ctcgcctgtt tctggatcaa
    28081 ctaatgtttc agctaatgtc agattcaata gacgtgtttt caaatctaat tttttgttta
    28141 ctttgtaacg accaacgttt gctaagtcgt aacgttttgg atcgaagaaa cgagcattca
    28201 gcaagttacg tgagctgtct gctgtttttg gttcgcctgg acgcaaacgt tcgtaaacgt
    28261 ctttcaaacc ttcttctgtt cttgagtcgc ttgcgttttt atgcaagtct ttttcgactg
    28321 tattgcgtaa tgtttcgctg tcgccgaaga tttcaaagat cgtatcatcg gaaccaaatc
    28381 ctaacgcacg aactaatacg gttaaaggaa tcttacgtgt acggtcgata cgtacataag
    28441 agatgtcttt tgcatcagtt tccatttcta gccaagctcc acggttaggg ataacagtag
    28501 aaccgaatcc ttcttttccg tttttgtcga cttttccatg gaaatagaca cctggtgaac
    28561 ggactaactg agaaacgatt actcgctctg ccccgttgat gatgaatgtt ccttgttctg
    28621 tcattaatgg gaaatcaccg aagaatactt cttgtgcttt gatttcgcca gtctcgcggt
    28681 ttgtcaaacg caatgttaca tgtaatggtg cagagtagtt tgcatcatgc gcacgagctt
    28741 ctgctactgt atactttggt tctttcaatt cataatctac aaattccaaa gatagattgc
    28801 cattgaagtc atcgattggc aaaatgtctt caaacatttc tctaagtccc tcatctaaga
    28861 accattggta agagtctgtt tgaatttcga tcaaatttgg taattccaac acttcactga
    28921 ttcttgcgaa acttctacgt tcgcgatgtt ttccgtattt tactacgtgt ccagccaagc
    28981 tcttcacccc tctaaaatgt cattcaaaaa gactacccga tcaattgtta caataatatt
    29041 tcaaatatta tttttaggta acaacagaca ttttttgcgg cttttaggca aaaaaaaacc
    29101 aaaaatagaa cattctcttg aaaccttact tcgtgagctt ctacttttgt ttccttatat
    29161 taaagccgaa acggacaata tttcgtttct gccttttctt catcagatag tttttgcaac
    29221 ttcatatact acacttattt tctataaaag tcaacacttc ctggcgtttc ttctgctttt
    29281 tcgcaacatt ttcttaatgt tttcaatttt atgttttcaa ttatctgaca attcttaatt
    29341 gacagacctt tttatctcgg ttatacttta gaaaattcat tttgtggagg aacttctatg
    29401 cgaaccaaca tcaaccaaat cgcaccaaca caactgaata acttttactt tagctacttt
    29461 agataggttt gtattcatca tgatggatac aaacgttaaa cgacagtttg tatctatgat
    29521 ggctaaagaa ctttgtattg cagcaaaaag ccacgtagac aaaatgctaa gtggctgagc
    29581 agtgaaaata caaagtaaaa gtatcaagca ttctactttt tcaatttatt ttccgacttt
    29641 tcaatccatt tggacatttt gtctgaatgg attttttgtt tcccaaaatt aaggaggaaa
    29701 aagaaatgaa aaaaaatata atcatcggat taggcgctgc cctgctacta gctttaggag
    29761 gttgcgcaca aaaagacaat tccgcagagg catcagatgg acaaaaaaca attggcgtat
    29821 tgcaacttgt acaacataac tcgttagatg ctgcctataa aggattcaaa gaaggattag
    29881 cagaagaagg gtataaagaa ggcgataatc taacaatcga ttatcaaaat gcccaaaaca
    29941 atcaagacaa cctgaaaagt atgagtgaga aactcgtcaa agaagatcct gatttgctac
    30001 ttggaatcgc cactccagca gcacaatctt tattaaatga aacaaccact atcccgatga
    30061 ctgtcacagc ggtcacagac ttggaacaag cccatttagt cacatccaat gaaaaacctg
    30121 gcggcaatgt gactggcacg acagatatgg tgccaatcga aaaacaaatc ggcttactgt
    30181 taaatatcgt gccagacgcc aaaacaatcg gcatcatgta taacaacggt gaagcaaact
    30241 ctaagatcca agctgatttg gcagaaaaag aattgaaaaa agcgggcgtc aaagtcaaag
    30301 tactgacagc aaattccaca aatgatgtcc aacaagtgac gaaaagtcta gctaaagatg
    30361 tagatggaat ctatattcct actgataaca cgttcgcaag tgcggcaagt gttgtcggtg
    30421 aagtcgcaaa agaaacaaaa acacctgtcg ttgctggcgc agttgatcaa gtcaaagacg
    30481 gcggtctagc aacagtagga atcgactacg aaagcttggg caaacaaaca gggatcatgg
    30541 cagcaaaaat cttagacggc aagaatccaa gtgaacttcc tgtcgaaaca gcgaatgatt
    30601 tggaactgta tgtcaataaa gacatggcca aagcattagg catcaatcca gacagcatca
    30661 aagaagctga ataaaacaca ggaggattct catgacaaat ttgctctctc ttttcttatc
    30721 atctgcatcg caaggggtct tatgggccct acttgcgatt ggtgtatacg tcactttccg
    30781 tatcttggac attgccgact tgactgctga aggaagcttt cctttaggtg cagggatcgc
    30841 ggcagtaagt attacaaatg gctatcatcc attgacagct tgtcttctag gctttttagg
    30901 gggtgcggca gcagggcttg tttccggact gcttcacaca aaattgaaaa ttcccgccct
    30961 tcttgcaggg atcatcacca tgactggttt atattctgtc acatcccgtg tgatgggtgc
    31021 gccgaacatc tctttattgg gtcagccaac gatctttcat tgggtcgagt cattcggcat
    31081 aacaaaagac aacgctgtac tgatcgtcgg tctgcttttt gctttgatcg ttgtatgttt
    31141 acttgttttg ttcttacgta cagaaacagg acttgctatt cgtgcaactg gcgataatct
    31201 ggcaatgagc gaagcaaacg ggatcaacac agataatatg aagatcatcg gttatatgat
    31261 ttctaatgga tgcattgctc tttctggctc cttacttgcg caaaacaacg gctttgctga
    31321 tttaaattct ggtattggaa cgatcgtaat tggacttgct tctattatca tcgcagaagt
    31381 tttgttacgt aaccagccac tatttctccg tctcttgact gtcgttttag gtgcggtcat
    31441 ttatcgtttt attttagcgt tagtcttcga actgaatgtt gaaccaagtg attcgaaact
    31501 tgcttctgct ttcgtgctag tgatctgtct ttctttcccg cagatccagc aaaaattcca
    31561 tttacctcaa aaaaagaaag gcggtagtgt caaatgaatg acgtcttaac attggaaaat
    31621 ctccatcata cctttgaaaa aggaacgatc aacgaaaatc atgtcctgaa aggcattaat
    31681 ctttccttag atcccggcga cttcgtgacg atcatcggtg gaaatggggc tggtaaatct
    31741 actttgctga acagcatcgc cggtacattt tctgtcgatc agggtcaaat tttattgaat
    31801 ggaaaaaata tcacgaaaaa atctgttgtc gaacgttcga aatccatcag tcgcgtattc
    31861 caagatccta aactagggac agccgttcgt ttaacggtag aagaaaatct tgctcttgct
    31921 atgaaacgag gaaaaaaacg cggcttcttc cgtggtgtca aaccacaaga ccgaacattt
    31981 ttcaaagacc agctggttcg gctaaatttg gggttggaaa atcgtttatc ctcagaaatc
    32041 ggtttgctgt ctggaggaca acgtcaagct attacgttat tgatggccac attacagcgt
    32101 ccagaactga tcttattaga tgaacacact gcagcgcttg accctgctac ttccaaaacg
    32161 gtgatggaat tgacagaaaa gctgatcact gagcagaatc tcactgcttt tatggtcact
    32221 catgacatgg aagacgcgat ccgctatggg agtcgactga tcatgctgca tcaaggaagg
    32281 atcgtcgtag atatccagca agaggaaaaa cagcagctca cagtgcccca attattagcg
    32341 ttgttcaaac aaaacagcgg cacggcatta aaagacgatc aagtactttt atcttcataa
    32401 tcagaaagag gatgggacaa aaaatgaacg cccaccctct tcttttttct ctttccttct
    32461 ttcgtttttg ctttatgtat caaccgttgt ttcttcgaaa actattttgt tctctccttc
    32521 ttcctgatag aatggatggg aaaggagctt gatgccatga caacgaaaga caaggtactt
    32581 caattattga aaaagacacc agattttctt tccggagaaa agttggcaca gcaactggaa
    32641 gtttcccgga caagtatttg gaaagccatc aaagaattgg aaaaggcagg ctatcgtttt
    32701 gagcacgggc ctacagggta tcgttacctg ccctctgacg tactagatgc aaaagaaatc
    32761 cagcaagagc tacggtcgtt tattcctgat ttgaaagtac aaacgatgtt gacttctgaa
    32821 tctacgatga aagatgccaa actggcagca gctcaaggag attctgtttc gaagttattt
    32881 gttgctgata cacaagaaca agctcgtgga cgttttggac ggcctttttt cgctgaacct
    32941 ggacgaggaa tctacatgag tctcttgctc catccagaca aacggtttga tgaattgcct
    33001 caatatacga tcatcgcagc cagtgcctgt gtgaaagcca ttgaatctgt aaccggtcgt
    33061 tctgcttcga tcaaatgggt caatgatatc tacatggatg gaaaaaaagt ctgtgggatt
    33121 ttatctgaag cagtcagtga tatggaaagc ggcaggatca gtcatatcat cattgggatc
    33181 gggcttaatt tttctgttcc tcaaaatcat tttccagctg atctccaaga aaaagccatc
    33241 tctgtctttc ccgacggaca agctagtgtc acaaggaatc agctaatcag caaaatctgg
    33301 caagaattgt tcacttatct ttctcaccca gaaaaagcgt tggacttcta taaagaaaaa
    33361 tcattcgtat tgggaaaaac cgtgtcgttc aatcaaaaag gaacgactta tgtcggtctt
    33421 gcaaaagaaa tcggtgatca tggcgaactg atcgtccaaa caaatgaaca gaagatgagt
    33481 ttgtcttctg gcgaaatcag tctcacatct atccgtacgc aataattatc agatttcaca
    33541 aaaggacacc tgatctcata cagtgtcctt ttttctgaat tctcttcaaa agactctcct
    33601 tattctatca gctgacagtt tctctatcct ctagaaaaag gtattctaaa aatatctata
    33661 aagcatggta cactttcttt aaatgaatca atgcaaaaaa caagagagtc atcagtttac
    33721 acgatcaaaa gagatagcag gccgcttcct ttttcaatct tatagataga ccatgggtaa
    33781 cgataaaaac aaaaaagaac ttgcgactta ttttgccgta agttcttttt tagctagtgc
    33841 cttaatctct taatcccaac aaacgtctcg catagatcac ctgaccagag tgcatagcag
    33901 catcatcaat aatagaaacg agacgcattc ctcgtgtgac tggtggtgtc cagttctcgt
    33961 caattacttc atctagctcg gaaggttcca gccttcttaa gtaagaaata gcaaaatcag
    34021 cagctcctcg caagtatcct agcagatctt ctatttgatt agcttggatc tgctttgctt
    34081 gttccagact atgcttccaa tcttgttcgt tatctgctat cgtcatcgga aaccggcttt
    34141 cccagtcttg actatgccaa attggagaag ttcctgctaa atcagcaatc tggaaatcta
    34201 attctcgagc ggtatgccaa gccagccaag tcattgattt gatctgcggg gctctatctt
    34261 ccactggaaa acgattggcc tcctcaatag agacgccttc aaacaaacgt tcaaaccgat
    34321 cgtatgcccg atccacactc tcgcatagca tatctaaata atccatttat tttcctcctt
    34381 tttatttatc ctacttactt tttcctaatt ctaggatacc tacttatatg ttactacaca
    34441 cccttatttt ttacacttta acagtcacca tcatcaatag tttggagatt gaaagaaaaa
    34501 gatagtgtcg aactatcaat tgaacaagaa gcaacaatat gaacgtttca ttaatattct
    34561 ttaaataaac aatgattttt caaacgaaca gtttaagact aggagaaaaa gagtataata
    34621 ggaaaatgtt tgaaaggaaa ggaaggggaa aaatgaaaaa aagggcaagt ttactagtcc
    34681 tagttgcttt gttgttcaat atcttttcgt atggtgtggc cgtttcagcg gaaacataca
    34741 ttcctaaaga ccctgggaat atttataatg atctaactgg taactatggc ttgttaggaa
    34801 ttgctagtca attccacgta tttgctaaaa ataagacaac tgtgaatgca catacagacg
    34861 gaaatatagc aacacatgaa cttgatgcaa aaaataattt tggtacagag cttcatgaag
    34921 gtttattgaa ccaagaaata aattatatac aaaaaactga ttctttcgct aattcttcag
    34981 gcatacctac aggtagcaca agaatgaata aatttgtcgt tggcagtaac gtggatgtag
    35041 cacttcaaga tggtcatcct acagtcaatg gatccaggct tgatcactta actccagatg
    35101 atttttataa agatcgtgct gggcatgaat atattgattt cgagcaggaa tttgctaaat
    35161 tgaatgtagc agcaaatgat cttgcaacga tcactccagc taaaacatat actgctgcag
    35221 attttccaga catgaacaat cggacaatcg atttaactga tttatcagat accgggtttt
    35281 tattggtaaa tatcgatgca gaagtgttaa cgatgaatac gccacttcaa atcattaatc
    35341 caaatgatca agtagttgta tttaatgtca tcaacagttc ttctgcattg aacgtacagt
    35401 caccaatcaa atacaatgat cgttcaaatc atgaaacaga agatttttcg gatgcgaata
    35461 tctcttggaa ttttggaaat gagatgactg atttgacaat cagtgctcct tttcaaggaa
    35521 caatccttgc gcctaatgct actatccgca ttactcaaaa ccaagacgga acgattatag
    35581 gaacaaatgt gattttagat gcagctacca atcgttggga tcctaacgaa atatttatca
    35641 gcgacaatgg tacagatacg acagacacaa gcgacagtac agatacatct accacaagtg
    35701 atagctcaga ttcatcaact tcaagcgaca gtacagatac tacctctacc acaagtgata
    35761 gcacggatac atcagcttca agcgacagta cagatactac ctctaccaca agtgatagca
    35821 cggacacatc agcttcaagt gacagtacag atactacctc taccacaagt gacagcacgg
    35881 acacgtcagc ttcaagcgac agtacagata ctacctctac cacaagtgat agcacggaca
    35941 catcagcttc aagtgacagt acagatacta cctctaccac aagtgatagc acggacacgt
    36001 cagcttcaag cgacagtacg gatacatcta ccacaacaag tgatagcacg gacacgtcag
    36061 cttcaagtga cagtacagat actacctcta ccacaagtga tagctcagat tcatctacca
    36121 ctacaagtga tagcacggac acgtcagctt caagtgacag tacagataca tcctctacca
    36181 caagtgatag ctcagattca tcaacttcaa gcgatagtac agacacgtcg tctaccacaa
    36241 gcgatacacg tcatgcaagt gtctccttct caaaaacaag ttcggataac aggacgaact
    36301 ttaacttaac taataaaaca agcaatgaca atggaaacaa atcaaaaaga gcacttccta
    36361 aaactggaag tcaatcgaat aattggataa cactcgcagg cgttatatta cttgtaatcg
    36421 gtttaagaat cacttttatg agttataaga aatcgaaaag gtaaaaaaat attcaagata
    36481 aaaaagagca acgtcgctaa cggacgttgc tctttatttt tgctttttat cataaataca
    36541 agaactacaa ttcaatttgt caaaaaacac gtagatttcc ttctgagaaa tttatttacg
    36601 tatcgaacct ttccctattc agtctttgcg atccaaaatc agttgggtaa gggaaaagag
    36661 attctctttt gttcgaagag aggtggcagg taatttcttt atttccttca aagccttttc
    36721 tgtgtaagag gccgctaact tcctagcttc ttccacgcct cctgtatgtt caacgatttt
    36781 gcgtacggcg tcgacatctt cttctgtcat tgccgctttc ttctctaaat aaggtagtag
    36841 ctttggtttg tttttttgca aagagtagat caacggtaaa gaatagaccc cttgacgcat
    36901 gtcttctagt acaggtttgc cgatttcctg gctctctttt gtataatcta aaatatcatc
    36961 gataatctga aaggccatcc cgatagaaag tccgatatct cctgcttttt ttgcgaagcg
    37021 ctcgcttgtt ccactttcaa aagcgccaac agaacaactt aattggaaca gttcagctgt
    37081 cttacctgaa atattttcca aatattcttt tacagaaagt tcataattat agcgatcatc
    37141 catctgccct aattcgccat tcaatacttt ttccatactg cgagaattca attggagact
    37201 tttcaaggaa gtggagtaat cagacaatag tttaaaacag cagacaaata aatagtctcc
    37261 tgcatagaca gaaacgacat taccaaactg actacggata ttaggctgac cacgtcgcag
    37321 atccgcttca tcaacgatat catcatggat cagtgtggcc gtatggagca tttcgataga
    37381 agctgccaaa gcgatggctt tgtctcgatc ttgctctggt ccaaattgtg agaacaatag
    37441 ctgataggca ggacgcaaca gctttccgcc ggcatggatc gtttctttga tggcttgttc
    37501 gacaggtttg tttttcaggc ggacagtttc ttccatccgt tttagtgttt ctgtcaattc
    37561 tttacttaaa gcaggatagt tttcccacat tggatgtagc ttcataaaaa aactccttgt
    37621 gtgacgatta ttttttggta aacattgggc tccatttttg tttggttccc tgctcataat
    37681 ctttttggaa tcgttgaagt gtctgcacat gtcgtaaaag ataattcgct gcgatcccga
    37741 ttgcaatccc tgataaaatc cctaaaactg aaaggactgg caagtacaac atgactgtcc
    37801 atgattgtgc aatgaaagaa gccatcaaaa gctgtccgac attatgcatg aaaccgccgg
    37861 ccgcactaat tccgatgata ctgacacgtt ttggtcctaa ttgcttgacc aataacattc
    37921 caaaataact aagcaaagca ccactcatac tataaaggaa tgtggaaatc gttccgccta
    37981 gcaaagtagt caggaatagt cgtagccaaa gtagtaagaa gctgtcttgt tttttcatgg
    38041 taaaaatggc aacgatcgtg attagattgg ctaagcctag ttttgcacca ggcgcaaaag
    38101 aaaaaggata agggatcata ttttccaata aaccaatgat cactccttgt gcaacaagta
    38161 gcgaaatata aatcattttt tgtaatttac tcatggtgtg tgaaggtcta ataaatcaga
    38221 ctgtcttcgt cacctccatc tgttgaacgg acttcgatca ctaatttatg tggcaaacag
    38281 acgatggttt cgccattttt cgttgcccag cctcgacgta cgcagatctg gtcatcgcaa
    38341 tctgcttctt ttatccgtac tcgatcgcca tctatctcga tcaagttata atctccgtgt
    38401 tcatctttgt aagtatatgt gttgctctct tctccagcca tcaaagggaa tgttttgatt
    38461 tctgtgccat ccacacgcag taccgcttct ttttctgctg ttgcggtgtt ttgctgaaga
    38521 ccaaaaatca tgactggtaa aaaagaaaga acagtcaaaa gcaaaataat aaaaacatcc
    38581 caaggtttga gcagactttt ttcagcaaat tctttaaggc tcatttttgt tctccttttt
    38641 ccagattaac tcacccaatt ttagcataaa aacaagaggt tgtgacacct gtgtcttgct
    38701 ttgagtaata agaacgaaga atagaaaaca gctttccatg ttttctaatt ctttgggctt
    38761 attaccgaga agcagcaggt ggaacaccgt ttataacaag aggttgtgac agaagtgggc
    38821 aacttcaaga aataagaagg aatttacgaa aattactttt caagtttttg tgaaatttcg
    38881 gcttattttt cgaagaagct acttctggaa caccgtttat aacaagaggt tgtaacagag
    38941 gttgtgacac ctgtgtcttg ctcatggagg cttatctcgg gcatcttatt cctttaattt
    39001 tacataaaaa ggaggctgtg acggtttgtc tcagcccctt tctattgaaa tcttgcattc
    39061 aaataacgtt ctttatctat ttatttcttg ccgtactggg aacttggtct accgtaccac
    39121 caattaccta gtgtacgttg tagccatgga attacccagc gatccaaccc aatcgcacgt
    39181 ccggaaccgt tcatcaatgc gaaagcaaca aaaatgaacc aaatgtttac ccagtaaaac
    39241 atgcctgata agcagaacgt gatcaccaat acaatcgttg tcgcactgca tagccatgtg
    39301 aataatccag caatcaatgc taatgccaag gcaatttcaa agaataccat gaatttttgg
    39361 aagaacattg ctacatcatt gtttggcatg atcacttgca tgatctttgt gaaccagtct
    39421 ggtgacttct caatcacagc cattggttct tcaccgtatg cataactcaa accaaaatgt
    39481 gcagcttgag tcgctgcttc tccggcactt gcccctgctc cgctggcagc tgtggttgca
    39541 tcaccagcag cagaagcacc actggcaaca tctgttacat tgtattccca tgtccaaggg
    39601 aacacactgt ttccagtgaa ccatgatcct tcaccaaacc aagtacttgg tttgaacact
    39661 tcaccattcc caatgatttt tttggaagct tcaacgaacc aaactaaacc atagaaaata
    39721 cgaagtggca cactccataa gacattgccg taacgagaag aatgtcctcg agtcacgttg
    39781 cgatcatctt tgatatggaa aaactcatgc attaaatatt ggaacatata ataaccagaa
    39841 cgaatatcaa agaagtattt caaattcacg atatgtttca ttacgatagc taaaaatccg
    39901 cttaaatgga tcttatcaaa taggttagct accccccatt tggcaccaat agaaaccata
    39961 aatccttgat agtttccttt aaatttatgc ttttctccgc ctttgatcga agccacgata
    40021 ttcgctgcgg ctgtgtgtcc tgtttgttca gcagcttgaa cgatctgcgg tgtcggtgtt
    40081 cctgggaatt cttcataaaa gactaaatca ccaatgatat agatgttttt atcttcgtag
    40141 ccttttgcct gcatatattc attggcgatc aaccgctgtc cgcgtgctga ttctaatcca
    40201 aagtcagcag cgtcagaagt tcctttgaca ccagctgtcc aaatcagtgt gtgagtcgga
    40261 atgttgcgtc cgtctttcaa tttgatatga tcagcagcca cttctacgat tggtgcattc
    40321 aataataatt ccacgttgtg cttacgcaaa tagcgttcag cttttgcagc atcatttcga
    40381 tccaacatat tcaagatcgt cggcattgcc tctacgacca tcagtgtgat ttcgtttgga
    40441 tctaatttat aatctttggc taggcgattt ttccagtcga tcagttcccc aatcatttca
    40501 ataccggtaa atccagaacc acagacaacg aaagtcagca tggctttacg cagttcatca
    40561 tctggttcca atgcagcttt tgctactgtc ttctcaatat gttcccgaat ccttacagaa
    40621 tcttcaaatg accaaagggt gaatccgtgt gctttgacac caggtgtacc aaagtcattc
    40681 ggctctccgc ccattccaag gatcagctga tcaaaaggat aggaacctaa tttggtcttg
    40741 acgatttttc gttctttatc gataccgatt acagtgtctg tgacaagttg tacattcttt
    40801 tgacgagcaa acaaatgctg cagatcgtat tggattgctt ctggttctac acgtccgcca
    40861 gctacttcat gcaactcggt catcatagta tggtacgaat gacgatcgat cagagtaatt
    40921 gctacatctt cttttttcag tttctttgcc aagtattttg tagctgaaac accggcatat
    40981 cctgctccta caacgacaat attttgcttt gccattgatc atccgctcct tatagactat
    41041 ctatataatg aatatatgat aattctttta gtttgatact tattacacaa tctccatata
    41101 ttatatagat gttctgttct tttgtctaac tccttttgga tttttttcaa attttaaaat
    41161 aaagcgtttt ttcacgaaat ttgctgaaag aaaacgtttg aaatattaca tgggttattt
    41221 atcaaaaata gttgacttat aggctaaaaa gattagaatg tataatgaat cacaaagaaa
    41281 aattgtggac tagaaatgga atggtggggt attaaaatga agaaaaaacg ttttgtaact
    41341 ggatttgccg tattagcatt ttcagctcta gtgttaggcg cttgcggcgc agatgacaac
    41401 ggaagctcaa actcttcttc tgaatcatct acagcacaat cttcgactgc aaaaagcaca
    41461 acagaatcat ctgcaaaagt tgtagctggc ggagatttgc aagacggcac atataaatta
    41521 gaagaaaaaa attattcaaa tggttaccgt gcagtctttg aaatggttgt aaaagacggc
    41581 aaaatcactg aatcaaaata tgataacgtc aatgaaaacg gcgaatcaaa aacaaaagat
    41641 gcagaataca acaaaaacat ggaagcaaaa tctggcacaa acccagaaaa atacattcct
    41701 gagttgaatg accaattctt aaaagcacaa agcgcaagcg gtgtggaagt cgtaactgga
    41761 gctactcact catctgaaag cttccaaaac tacgcacaac aattgatcca agctgctcaa
    41821 gctggtaaca cagatacaat cgaaatcgac aatggtgctg atttgaaaga cggcacttac
    41881 aagcttgaag aaaagaacta ctctaacggc taccgtgtgc aattcgaaat gacagttgct
    41941 ggcggcaaag taactgaatc aaactttgat tatatcgaca aagacggtaa atcaaaacaa
    42001 gatgatacag aatataatga aaatatgaaa gcaaaaagcg gtacagaacc aaaaacttac
    42061 atccctactc tgaacgacga attcgtcaaa gcaatgggcg aagaagatgg ctcacctgct
    42121 aatgtagaag ttgttacagg tgctacacac agctcacatt cattcatcat gtacgcacaa
    42181 caattagtga atgcagctga aaaaggcgac actcaaacaa tcgaagtaga taatatcgta
    42241 acagaaaaat aatcacataa tcatactaat aaaagttgga gggtgggacg atagccagat
    42301 taggcagtcg tctcaccttt caaaatgaag agaggaaaaa gatgcggaaa aaactactat
    42361 tttccttaat cacactgggc atctctttta tggtgctaac tggctgcagc aactcagcaa
    42421 ataaaacaac cactgaaagt tcagcagcta ccaagatatt gaaagatcca tattctgatg
    42481 aacagttctt gttagggact tacgttcgta tccgtgtgta tgatgaaggc aaagaatcag
    42541 cattgaaacc tgccttcgat cgagtaaaag aacttggtga taaaatcacg atcaatcaaa
    42601 aaggttctga gatcgatgaa gtgaatgagc aagctgggat caaaccagta aaagtttctg
    42661 atgacgtcta cacgttagtc aagcgggcct acgaatatag ccaagattct caaggcggat
    42721 tcgatatggc gattggtgca atcacacaat tatggcgaat cggttttgat gacgccagaa
    42781 aaccttccca agaagaaatc gatcaggcat tgaaattagt ggattatcat aagatcgaac
    42841 taaatgacaa agaaaaaact gtttatctaa aagaaaaagg aatgatcatc gatttaggtg
    42901 caatcgccaa aggttacatt acggacgaag tagtgaaagt cttgaaaaaa caaggagtga
    42961 ccactgccat cgttgacttg ggcggtaatg tctatgtctt aggccacagc ccaagaggcg
    43021 aaaaccaaga ctggacagtc ggcatccaag atccgaacat ggctcgcgga tctgttttag
    43081 gttctattaa agaacggaac aaaacattag ttacctctgg aatttacgag cgttatttag
    43141 aagtagatgg caaaaaatac catcatttgt ttgatccaaa aacgggttat ccgttcgaca
    43201 atgatatcgc aagtgtcacg atcataacag ataaatcaat tgatggtgac gggttgtcta
    43261 cagcagtctt ttcaatgggt gtgaaaaaag gactggaata cgtcgaaagc gaattgaata
    43321 acgggacgga agcgatcttc gtgacaaaag acgataaagt atatgtgacc gatccaatca
    43381 aagacacctt caaattatcg gaggactccc attacacgat gggtgaccgt tctgaactaa
    43441 aataaggagt acgaaccatg acactaaaaa tctttttaga agtagttgaa atacgaacaa
    43501 aggtggctag tgtatttcct tttgcggtag gggtattatt ctctatcgct ttttttcatg
    43561 agatacattg gctaaacact tttttatttt ttattggaat gctagttttt gatttagcga
    43621 ctaccgctat caataattac atggattatg aaaaggctca ttctgaagta tataagtatg
    43681 aagaaaatgt cattggccgc agaaatctat ctcctgtatt gattcgaaac atgattttag
    43741 ctatgattgc atttgttttt gttatcggcg ttattctaac gatcaatacg ggttggcttt
    43801 tacttttgat gggatttatc tgttgtttta ttggagtatt ctatacattc ggaccgattc
    43861 ctttatctcg aatgccttta ggggaaattt tcagtggggt gactatgggc cttggaattt
    43921 ttgccatggt cgtttatgtc aatacattcg gttcagatgt ctatgatctg acagtcaact
    43981 tttcatctgg acaatttgat ttggtaggaa atctttgggc tatagcagca atcgtattag
    44041 cttccttacc cttggtgttt acgattgcca atatcatgtt ggctaataat ttgcgggatc
    44101 ttgaccgtga tattgaaaat catcgctata cactagtttt ttatatcgga cgtcctgcgg
    44161 gaacagtctt attccagcta ttgatgtatg cttgctattt cgtgatttta atggggttgt
    44221 tgagcggtat ctatgaatgg ccgatcttgg tcaccttctt gaccttgcca attgtgaaga
    44281 agcatttgga tcaattcaag caaacgttac cccagcctat cagtttcagc tattccatca
    44341 aaaatatggt cttattcaat gccagttatg tattggggct attactaaca atcattatgc
    44401 aagccattta acagcatgaa gaggttgtga aaaaactgcc ctgcatcaag taataagaac
    44461 agccaaataa aaatagctcc ttatattttt cgtttggttg ggcttattac cgcagatgca
    44521 agcttttgaa caccgtttat caggaggttg tgaaaaagtc gcttagtttc gagtattaag
    44581 aaaaattttg tgaaaatggc tttccacatt tttgcataaa tttggcttaa taccgagaaa
    44641 ctggcttttg aacaccgttt atcagaggtt gtaaaatcag tgttttgtcc tgagtattag
    44701 agaaacaaat ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgaagga
    44761 cagctgattg aacactattt gttcggaaaa agtgactaac tatgacacaa tttttttcac
    44821 agtccctttt ttcacttgat ttgattcgta ccagcgaact tgacgagaac tttcttggtt
    44881 tggtaactat atggtattct tttaacatcc tcgtttgctt cttctaattt atttatacaa
    44941 agtcacactt ttttaaacat ctgttcttcg atacatttct atttctttta aacatcgata
    45001 ccaatatttt gaacttaaga gtgcatacca aatggattca tttactcttc gtcagttacg
    45061 aagataatca aaatctccaa cttccctact tatttcgttt tgagaattat cgaagcaatc
    45121 ttacataaat aactaaaaaa caaaaaacca gaaaatcagt atactgattt tctggtttta
    45181 catggtttgt tcaataaaaa gctgttggaa ctgttaatat taaattatcg catcgttacg
    45241 aattcttccg ctcctgttgg atggatggct actgtattgt caaagtcttc tttagttgca
    45301 cccatcttga tagccacggc aaaaccttgc agcatctcat cgacaccaac accaatagca
    45361 tgtaagccga cgattctttc ttcttttccg acacagatca atttcatttc gcatttttgg
    45421 cgataatcat ttaatgcaaa gtacattggg gtaaagcgtg aacgataaac tttcaattca
    45481 ttttcgccat atttttccaa tgcttcttct tctgtcaaac caattgttgc aattggtgga
    45541 tgcgtaaaga cgactgtcgg aacaagttta tagtcaagat aagaatcttt ctttccatta
    45601 aataaacgtt ctgataaacg tctaccagct gcgattgcaa caggagtcag atctaattta
    45661 ccgatcacat caccaacagc aaaaatatgt tcatccgttg tattttggta tttatctact
    45721 ttgataaacc cttttttgtc caattccaca tttgtatttt ccagacctaa tttttcggta
    45781 ttcggtacac gtccaccggc aaaaagtaca caatcaccag ttaaggtttc accattttca
    45841 aatagcaccg tatattcgtc attgttttta gtaatttctt tagcaatatg atgtgcgtaa
    45901 gtttttattc cagcttcttg gtacatttgg atcaaattgt ccgaaagcat tttatcaaac
    45961 gttctaagtg gtcgttcttt tcgatatgcc cacatgactt cactacctaa accacgaaat
    46021 acacctgaaa gttcagccgc aatgtatcca gcacctaaaa cgattgctct cttaggtaac
    46081 tctgttaatt caaaaaatcc atttgaatca attgcgtatt ctccaccagg aatggtcatt
    46141 ttacttgcac ggcctccagt agcgatcaag attttaggag cacgataggt ttcaccgttt
    46201 acttcgatcg tttgactatc gataaaagta gcgtaacctt ttatagcctc gacatgattg
    46261 ctatctaatc ctctttgata agcaccgtgt agaaaatcaa tatatttttc tcgtctttct
    46321 actagaccgg cgaaatcaac attttttaaa tctgcttgga taccgtaact tgaggcatct
    46381 cgttcaattg tttccaaaat cgtacttgct tgccacataa cttttttagg tacacaaccg
    46441 acgttgacac atgttccgcc caattcattc gcttcaatca gcaaaacttt tgcgccatgc
    46501 atccctgctc tgtttgctga agcaataccg ccagagccgc caccaattac gatgtaatca
    46561 tatatttgca ttttgttcct ccttattgaa gagatcaatc aaaaccttta tttaacgatc
    46621 ctttttctac agaaaacaag tgtaacactt ttcttgaatt ttgtatgcga agatgcttaa
    46681 aacagggata tatcagcttt ttccttattt acgttttcgg atcatatctc caggtttcac
    46741 cggctgtgcg actggcatag ttaaaatcat cattggattt ggtgctcggt caatggattc
    46801 gccttcttca ttatgcataa cttcaacggt ttgactgaaa tgactgaatc ctggaccata
    46861 aaattcgatt tcatctccta cagaaaacaa gtttctctga cgtatcgtag caatctgtgt
    46921 tgcctcatca taagataata cttcaccgac aaatttatat actgggattt tacgacgttc
    46981 accgaataat tgttcgtttt cagttggtgt attgtagtaa aaacctgtag ctaattctcg
    47041 ttgtgctact ttccataact cgtcgatcca ttcttgcttg cagacatagt tttcaggatc
    47101 ttccatataa ctgtctacag ccgctttata gacatttgac accgtagata cataatggat
    47161 cgatttcatt cttccttcga tcttgaagct gtctacgccg ttttcaatca attctggaat
    47221 atgttcgatc attgacatat ccactgcact catcgagaat tcttcttcca cttcgcctgt
    47281 atcagttaaa ctgtttcgtt cttgaccaaa aggcatatcg aacaatccat acttccagcg
    47341 acaagattga gaacatccgc cacggtttgc atcccgcatc gacatatggt tggacaatgt
    47401 gcatcgacca gaataagaga tacacatggc accatggata aatgcttcga tttcggtatc
    47461 cgtattttta cgaatctctg ccacttcctc cattgaaact tcacgagcta aaacgacacg
    47521 ttccaaccct tcttctttcc agaattccaa tgtctcaaaa ttagttgctg aagcttgagt
    47581 ggataaatgg atcggcagac ctggggcttc tgtcgcacaa atttcgatca aagctggatc
    47641 agaaacaatc actgcagaaa taccgacatc acgcaaactg cggaaaaatt cccctgctcc
    47701 atcttcattt ccttcatggg tgaccatatt agcagcaacg tataccttcg catcatgttc
    47761 ttttgcaaaa gcaactcctt cagccatttc ttcataagta aaattacctg cacggcttct
    47821 taaaccatat gcattcccgc caatatatac tgcatctgct ccataatgga tcgcggtttt
    47881 taacttttcc agtgttcctg ctggcgctag gatttctggt cgtttcaatt ttctttttac
    47941 tgtcatttct ttcatcatac tccttatttg atagcagaag gatcaatata aaagaatcct
    48001 gtatctaatt cacggttttc aggatgcaat ttactgattt cgctagtcat tttttccgct
    48061 ttttcttgat cccagctacc ttctaaaatt tgtttttttg cttcggcgaa tagtcgagtg
    48121 atgtttacga atttttcgcc tggagtaaat aatccgtcca atttccatgt acagtaatga
    48181 tgctgataaa gttcattcaa ttcattcgag agattcagat cattgctggc aaaaatatgt
    48241 gtgccatgac tatcttcata aatagaataa tgtgtctctt cttttttagg ttccgagata
    48301 aaaagacctc tttcacgatc tttttgttcg tcttgtttcg tatagttata gtaattctgt
    48361 agcagtggac gtttggattg atggatgcat gtagcaccat acacaagggt ttctacagga
    48421 atatcgagtt tttcttccat cgccttcatc tcttcaaaag gaacttcacg agcaagtact
    48481 gctccaactg cgcctttttt cgcccagaaa ttgatttgac gtgcgctcgt tactaatgtt
    48541 tcagcatcat aaatatacgg tatacgcaat tcaggatttt ttttcatcgt ataaataata
    48601 cctgtatcac caactgtgat cacatctacg tttatttctt ttaaaaaagc caaatattca
    48661 ggtacatttt tcattttttc aggatgaatg atcccattta cagcaatatt cgctttttta
    48721 ccatacttgt gtgctaattc taccaattgt cgctgttctt ctcgtgtaaa tgaagcaggc
    48781 agacgcaatc caaattgctc ttcaccgaaa tatagtgtat ctgcacctgc agcaagcaac
    48841 tgttctgctt gttcaatagt ttctactgtg gttatgagtt cgatcataat tttctcctcc
    48901 tacaacttca taatagtagc atagctctaa aaactttcca atacttcttc tatttaaagt
    48961 cggatttttg aaaattattt cacaaaaaat caaaataaag ttcgatatat tctgtccaaa
    49021 tataaaaaga gattgtgaca aaaatcttgt cacaacctct taatcaagtc ttactattat
    49081 aaaaattcag ctacacaggc caagtaacta tagggaacct actgtttcct ttttaggtcc
    49141 gcgaacattc aatgtgatct taccttttga agcacctact gttacgtggt cacctaaacg
    49201 aatttctccg ccaagcaaag cctcgctcaa tcgatcttca atttcttttt gaagtgcgcg
    49261 acggattgga cgtgcaccat attcaggatc aaatccagct ttcccgatca catcgattgc
    49321 agatggtgtg attttcactt gaatatcttg ttctttcaat cgtttgataa tcgctttgct
    49381 catgatttgg acgattgtat ggatttcatc tttactcaat gaatggaaga cgacagtctc
    49441 atcgattcga ttcaagaatt caggtcggaa agctttcttt aactcttcta agatacgttt
    49501 ttgcatggct ttgtgatctt tagtaacatc ttggacattg aatccgacat ttttttcttc
    49561 tcgaatttgt gtcgctccga tatttgaagt cataatcatg attgtatttc taaagtccac
    49621 ttttctacct ttagaatctg ttaaatgacc atcatccaat acttgcagaa gtaaattgaa
    49681 aacgtctgga tgtgctttct ccacttcatc taagagaatc actgaatatg gtttttgacg
    49741 aattttttct gtcaactgtc caccttcatc ataccctacg tatcctggag gagacccgat
    49801 taatcggctt gtactgtatt tttccataaa ttctgacata tcaacacgga tcagggcatc
    49861 ttcacttcca aacatgactt ctgaaagtgc tttggccaat tctgtttttc cgacaccagt
    49921 tggtccaagg aacatgaatg aaccaattgg acgatcagga tctttcaatc cgcttcgtgc
    49981 acggcggatc gcacgtgaaa ctgctttgac agcctcatct tgaccaacga cacgttcatg
    50041 cagaagtcct tccagttcta acaagcgttc gctttctttt ttctccaact gctgtagagg
    50101 gacaccagtc cactccgata caactgtagc aacatcttct tctgttacac gatcagaata
    50161 accttgctcc tgttttgctt caattgcaga aactttttgc agctttttac gtagtgcttt
    50221 ttcttgtctg cgtaattgag cagcattttc aaagtcttgt ttttggatcg ctgcttcctt
    50281 ttcttgtact agttcatcga tttctagttt gatcacagtt gattttgtta agtgatcggt
    50341 ttgatccaaa cggactttcg ctgctgattc atcgatcaaa tcaattgctt tatcgggtag
    50401 ttgacgagaa gtgatataac gaacagaaag attgactgct gctcgtacag cttcatctgt
    50461 gatctccact ccatggtgct cttcatatct tgtacgtaat ccttgaagaa tcacttctgc
    50521 ttcttcagga gttggctcat ctacttgaat gcgagcaaaa cgtcgctcta atgcagaatc
    50581 tttttcgata tatttttgat attcatctag ggtcgttgct ccgatcgttt gtaattctcc
    50641 tcgagctaac gccggtttca agatattcga agcatcaatt gctccttctg ctccacctgc
    50701 accaattaag gtatgcaatt catcaatgaa taagattact tgaccatcat tatagatttc
    50761 gtcgatgacc tttttcattc gatcttcaaa ttcaccgcga tatttcgtac cagcaaccaa
    50821 agatcccata tcaagcatca tcaggcgctt ttcttgcatg tcttctggca cttcacctaa
    50881 aatgattttt tgagctaacc cttcagcaat ggctgttttg cctacaccag gttcacccac
    50941 cagtacaggg ttattctttg tccgtcggct aagaatctgg ataagccgtt tcacttctct
    51001 cgaacgacca acaactgggt ccagcttgtt ttcttttgct aatttcgtca aatcacgtgc
    51061 taatgaatct agcgtaggtg ttccttgcgg tgtttgccgt ttatcttgta catttacatt
    51121 tctacgacga ttcattcctt ttccagcaga atcaccagct agccccattt tttgtttcag
    51181 aacttgacgg gcttttgaaa ggctgatacc taagttgatc atgattcgag tagccatgat
    51241 actttcatct tttaataagc tcatcaaaat atgttctgtt ccaacttttt gagaaccagt
    51301 tttcttcact tcgctgctag ctaaagcaaa aacttgtttc attcttggtg aatatggaag
    51361 aaagactcct ttagggtaag aacggatacc accataacca atcagatgtt caatttcttc
    51421 ataaatttcc gtttcattca aatccatttc acgtaatact tttccagcaa ttccattttg
    51481 ctcgaccact aaggctagta aaacatgttc tgaactaact gattgatgtt tcaaccgttt
    51541 tgcttcttct tgtgcaattt ctaatactgc ttgggctctt tcagtaaaaa gttcttccat
    51601 ctaatctcac ttcccatctt cataacttaa acgttccaga aatgctcgga gaatccgagc
    51661 acgtgtatga tcttcatatt cattgaaatt caatgtgttt tttgcaattg cactcaacat
    51721 caagtttcct tctttttttg taattatttg gtcttcataa agtttttgaa taatagcaaa
    51781 agcatttttc tcactgattg tatcatcaaa taactgattt atctgctcaa gtaattgttt
    51841 tttatctgaa atccttactt ttgcaattcg tatataacca ccaccaccac gtttgctttc
    51901 tactagataa ccacgttgga tggtaaaacg ggtattaatc acatagttga tttgtgaagg
    51961 aacacagtta aagaggtctg ccatttcaat ccttcgaatc tcgatcattt cactattttc
    52021 cagaattttc tttatatatg attcaattaa atccgaggta ttctgatgtg ccatcttatt
    52081 cattcccttt gactaatatt gaccttaatt ataacgaatt tgataataga aagaaagaag
    52141 aacgcttttt gttaaataaa tcctttagaa tcaacaaaaa aaaatacgga atatactatt
    52201 ccgtatcgac gcgcccaaga ggagtcgaac ccctaacctt ttgatccgta gtcaaacact
    52261 ctatccagtt gagctatggg cgcatattca atttaaaaaa attataaatc atttgaaaac
    52321 aaaaagcaag ataaaaaaaa tcgggaagac aggattcgaa cctgcgaccc cttggtccca
    52381 aaccaagtgc tctaccaagc tgagctactt cccgtttaaa aaataaaaaa gac
//
LOCUS       DAFEKH010000019        49887 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.020, whole genome shotgun sequence.
ACCESSION   DAFEKH010000019
VERSION     DAFEKH010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 49887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49887
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.020"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(85..264)
                     /gene="rpmF"
                     /locus_tag="LP386_001172"
     CDS             complement(85..264)
                     /gene="rpmF"
                     /locus_tag="LP386_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBL1918420.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(322..891)
                     /locus_tag="LP386_001173"
     CDS             complement(322..891)
                     /locus_tag="LP386_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HBL1918421.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1077..1979
                     /locus_tag="LP386_001174"
     CDS             1077..1979
                     /locus_tag="LP386_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL1918422.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="LP386_001175"
     CDS             complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="LP386_001175"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HBL1918423.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="LP386_001176"
     CDS             complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="LP386_001176"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBL1918424.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="LP386_001177"
     CDS             complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="LP386_001177"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HBL1918425.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8547..8732
                     /locus_tag="LP386_001178"
     CDS             8547..8732
                     /locus_tag="LP386_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HBL1918426.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8794..9990)
                     /locus_tag="LP386_001179"
     CDS             complement(8794..9990)
                     /locus_tag="LP386_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBL1918427.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10160..11596)
                     /locus_tag="LP386_001180"
     CDS             complement(10160..11596)
                     /locus_tag="LP386_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBL1918428.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11889..12698
                     /locus_tag="LP386_001181"
     CDS             11889..12698
                     /locus_tag="LP386_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL1918429.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
     gene            complement(12884..15037)
                     /locus_tag="LP386_001182"
     CDS             complement(12884..15037)
                     /locus_tag="LP386_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HBL1918430.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(15331..16179)
                     /locus_tag="LP386_001183"
     CDS             complement(15331..16179)
                     /locus_tag="LP386_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL1918431.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(16403..18343)
                     /gene="thrS"
                     /locus_tag="LP386_001184"
     CDS             complement(16403..18343)
                     /gene="thrS"
                     /locus_tag="LP386_001184"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HBL1918432.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(18680..18859)
                     /locus_tag="LP386_001185"
     CDS             complement(18680..18859)
                     /locus_tag="LP386_001185"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HBL1918433.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(18906..20729)
                     /gene="cadA"
                     /locus_tag="LP386_001186"
     CDS             complement(18906..20729)
                     /gene="cadA"
                     /locus_tag="LP386_001186"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBL1918434.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQFVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            21007..23286
                     /locus_tag="LP386_001187"
     CDS             21007..23286
                     /locus_tag="LP386_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL1918435.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(23379..24026)
                     /locus_tag="LP386_001188"
     CDS             complement(23379..24026)
                     /locus_tag="LP386_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918436.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(24205..24924)
                     /locus_tag="LP386_001189"
     CDS             complement(24205..24924)
                     /locus_tag="LP386_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1918437.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(25055..26206)
                     /locus_tag="LP386_001190"
     CDS             complement(25055..26206)
                     /locus_tag="LP386_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HBL1918438.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(26423..27163)
                     /locus_tag="LP386_001191"
     CDS             complement(26423..27163)
                     /locus_tag="LP386_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL1918439.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(27167..27490)
                     /gene="rsfS"
                     /locus_tag="LP386_001192"
     CDS             complement(27167..27490)
                     /gene="rsfS"
                     /locus_tag="LP386_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HBL1918440.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(27547..28140)
                     /gene="yqeK"
                     /locus_tag="LP386_001193"
     CDS             complement(27547..28140)
                     /gene="yqeK"
                     /locus_tag="LP386_001193"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HBL1918441.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(28124..28774)
                     /locus_tag="LP386_001194"
     CDS             complement(28124..28774)
                     /locus_tag="LP386_001194"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HBL1918442.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(28784..29095)
                     /gene="yhbY"
                     /locus_tag="LP386_001195"
     CDS             complement(28784..29095)
                     /gene="yhbY"
                     /locus_tag="LP386_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HBL1918443.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(29111..30220)
                     /gene="yqeH"
                     /locus_tag="LP386_001196"
     CDS             complement(29111..30220)
                     /gene="yqeH"
                     /locus_tag="LP386_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HBL1918444.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(30217..30744)
                     /locus_tag="LP386_001197"
     CDS             complement(30217..30744)
                     /locus_tag="LP386_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HBL1918445.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(30924..31709)
                     /locus_tag="LP386_001198"
     CDS             complement(30924..31709)
                     /locus_tag="LP386_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HBL1918446.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(31702..32571)
                     /locus_tag="LP386_001199"
     CDS             complement(31702..32571)
                     /locus_tag="LP386_001199"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HBL1918447.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(32572..33951)
                     /locus_tag="LP386_001200"
     CDS             complement(32572..33951)
                     /locus_tag="LP386_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HBL1918448.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(33959..34378)
                     /gene="fabZ"
                     /locus_tag="LP386_001201"
     CDS             complement(33959..34378)
                     /gene="fabZ"
                     /locus_tag="LP386_001201"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBL1918449.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKTSAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(34403..34879)
                     /gene="accB"
                     /locus_tag="LP386_001202"
     CDS             complement(34403..34879)
                     /gene="accB"
                     /locus_tag="LP386_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HBL1918450.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(34882..36117)
                     /gene="fabF"
                     /locus_tag="LP386_001203"
     CDS             complement(34882..36117)
                     /gene="fabF"
                     /locus_tag="LP386_001203"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HBL1918451.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(36136..36873)
                     /gene="fabG"
                     /locus_tag="LP386_001204"
     CDS             complement(36136..36873)
                     /gene="fabG"
                     /locus_tag="LP386_001204"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HBL1918452.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(36885..37802)
                     /gene="fabD"
                     /locus_tag="LP386_001205"
     CDS             complement(36885..37802)
                     /gene="fabD"
                     /locus_tag="LP386_001205"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBL1918453.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(37909..38133)
                     /locus_tag="LP386_001206"
     CDS             complement(37909..38133)
                     /locus_tag="LP386_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBL1918454.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(38186..39148)
                     /locus_tag="LP386_001207"
     CDS             complement(38186..39148)
                     /locus_tag="LP386_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HBL1918455.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(39158..39598)
                     /locus_tag="LP386_001208"
     CDS             complement(39158..39598)
                     /locus_tag="LP386_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL1918456.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            39904..40869
                     /locus_tag="LP386_001209"
     CDS             39904..40869
                     /locus_tag="LP386_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBL1918457.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(40926..41156)
                     /locus_tag="LP386_001210"
     CDS             complement(40926..41156)
                     /locus_tag="LP386_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HBL1918458.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(41242..42129)
                     /locus_tag="LP386_001211"
     CDS             complement(41242..42129)
                     /locus_tag="LP386_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HBL1918459.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(42218..43441)
                     /locus_tag="LP386_001212"
     CDS             complement(42218..43441)
                     /locus_tag="LP386_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBL1918460.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(43458..44504)
                     /locus_tag="LP386_001213"
     CDS             complement(43458..44504)
                     /locus_tag="LP386_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBL1918461.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(44668..46395)
                     /gene="ptsP"
                     /locus_tag="LP386_001214"
     CDS             complement(44668..46395)
                     /gene="ptsP"
                     /locus_tag="LP386_001214"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBL1918462.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIDMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDTMEEV
                     VELVHEYVK"
     gene            complement(46395..46661)
                     /locus_tag="LP386_001215"
     CDS             complement(46395..46661)
                     /locus_tag="LP386_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HBL1918463.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            47140..49374
                     /locus_tag="LP386_001216"
     CDS             47140..49374
                     /locus_tag="LP386_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL1918464.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            49522..49842
                     /locus_tag="LP386_001217"
     CDS             49522..49842
                     /locus_tag="LP386_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBL1918465.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
BASE COUNT        14254 a        10708 c         8729 g        16196 t
ORIGIN      
        1 attttttatt taccgactac aaaaaaataa acctcaaggc tccatggtta gccttgaggt
       61 tttacatttt ctaattaaaa tgtattaagc ttcttttgac attacgtcct taccatcata
      121 gtaaccacaa tttgcacata cgtgatggct ttttttcatt tcaccacagt ttggacattc
      181 gtttaaccct ttgattgtca atttgtagtg tgtacgacgt tttgcttttt tagcttttga
      241 tgttcttcta gctggtactg ccattttgct acacctcctt gtaaagtctt gtatctaaat
      301 tagacacaat atattccaat cttacttgtt atcgtcgtct tttgatttag aatcaaaaag
      361 ttcagatagt tttgcaagac gaggatcaat tttattctcg gcttcttcca tttttctgcg
      421 ctggtattct tcttcggaaa caacttccca atcattgcct tttggaagtt ctgttgctgc
      481 ttcctcttct tttgtcaata cccgcattgg aatcgccaat aagatgttgt cttcaatcga
      541 ctctgctaaa ttcaataatg gaccttcaat tagcaaaatc tcatctgcag acatttgttc
      601 atctctactt tggaattgtt cttctgtcat gaatacttcg tctacagaaa aatccatggg
      661 cagttcaaca ggttctagtg aacgtgttga aggaactgtc aaagtcgtct gcacagtgta
      721 atgaacgata tagcctttct tatcaactga gaccaaacct tcgacttcca ctggcgcaac
      781 atcaagtatt aaattgtctc gcttcatgag agcggctttc aagtcgagcg tctcatgaaa
      841 agttaacggt gtctcctggt attttctcaa ttccaataaa gaccatttca tttttcatca
      901 ctcctaagca acaaaagcaa ttatacaggg caaaaagcat gttgtcaatg aaattttctt
      961 gacaccttgc agttcataaa aaaacagaaa aatctttatt agaaagcctc tgtttgctat
     1021 catcctcaga atcatttaca ataatcatta ttccattaaa ggagcggatg atcttcatga
     1081 acacgaaaga tatcgaatac tatgtccaaa tcgtcaaaca aaaaaatttt acgaaagtgg
     1141 ctaattattt ccgtgtgagc caacctacta ttacatatgc attacaacgt cttgaaaaag
     1201 agtttgacac cgtacttatt acaagagatc gatcgcatca cgaattaatc gtcacgcctt
     1261 ctggaaagca gctgtttctc catgcacaaa ccattctcca agagatttct actgcaagag
     1321 ctgaaatcac tcagttgcaa aagaaaaagc ttcgttttgg catgcctcct attatcggca
     1381 atgaatactt tcctaaactg tcaagttact ttatcaagca tgaattgatg aatcaaattg
     1441 agattaccga tggaggctct cgggacttat acgggatgat ccgacaaggg aggatcgatt
     1501 tagctgtatt aggctcaaca cagccaatcg tggatcaata tttagaaaca gagttacttt
     1561 tggacaaacg tttcatgatc gtcgtgccac ctacacatcc tctttccaag caggatactg
     1621 tctctttcaa agatatagca gatgaacagt ttgtactatt gaacgaacat tatgtccacc
     1681 ccgcagcatt cactaagctt tctaaacaaa cacatactca tccaaaagtt gtttatcaaa
     1741 gcaatgactt gacgatttta aagagtatgg tccgagaaaa tgtgggtatc ggttttttgg
     1801 cagagattgc tgtccatcct gaagatcatt tagtttgcct ccctctttca gatgaagttc
     1861 agcctcgctt cttgatttca ttggcaaaac gaacacagca gatcgtcacg cctcttcaag
     1921 aacaagtagt ccaagttatc catgaattcg ttacagcaca aaaaaacagc tcttcgtaaa
     1981 agaagagctg tttttatttt ttattaagct aaattagata gctgttgttt cgccacggta
     2041 aacgatgccg cgacgtgaat caacggtaat caattcacct tctgtaattg ttgttgttgc
     2101 gcctttagca ccaacgatta caggaatatc ttgtgcaatt cctacaactg cagcgtgaga
     2161 agtcaatccg ccttcttcaa cgataacagc agctgctttt tcgattgcag gcatatattc
     2221 tttgtcagtt gatggtacaa ctagaaccat tccgtctttt gcttttttta cagcttcttc
     2281 agcagatgaa gcaataactg catttgcaac gacagatttt tgtccaacgc cttgagcttc
     2341 taataattta gaaccaatca tttgaatttt catcacgtta gttgttccgc gttcaccaac
     2401 tggtacacca gcagtgatca agattaaatc gccttctgat gcgaaaccta attcaacagc
     2461 ttttttagct gctagttcaa acatttcatc agttgttgat ggtttttcag caactgttgg
     2521 gtaaacgccc cagtttaaca tcaaaccacg ttttgtgcgt tcgtcaaaag taacagccaa
     2581 gatatctgca tctggacgat attttgaaat catttttgca gtgtatcctg attcagttgc
     2641 agcaacgatt gttttcacgc ctagattttt tgcagcacga gctacagata aaccgattgt
     2701 ttcagttaca tctgttttat cgaattcgtt caattggaat gtacctaatt ctgataatgc
     2761 attttcagct tcttggtcga tacgtgccat tgttgaaaca gcttcaactg ggtagtcccc
     2821 gtttgcagat tcaccagata gcattgttgc atctgtgcca tcaaatacag cgttagcaac
     2881 gtcagaagct tccgcacgtg ttggacgtgg gttttcttgc attgattcta acatttgtgt
     2941 agcagtgata actgggatac cagcagcatt acattttttg ataatgcgtt tttgaaccat
     3001 tggtactagt tcagctggga tttcaacacc catatctccg cgggcaatca taacaccgtc
     3061 agaaactttg atgatttcgt caatgttgtc gataccttct tgagattcga ttttagggaa
     3121 gatttgaaca tgagtcatgt ctttttcttc taagatttcg cggatatcta gaacgtcttg
     3181 tgctttacgt acaaaacttg cagcgataaa gtcgatatcg ttgtctaaac caaaacgaat
     3241 atcgtcagca tcttttggag taatacctgg caaactaata gaaacgcctg gtgcatttac
     3301 ccctttacgt gatcctagca tacctgcatt tttaacttct acgactaatt cacggtttgc
     3361 ttcgtctttt tcaatgattt gcatatcgat caaaccatca tcaaataaaa tgtgtccgcc
     3421 aacgtgaaca tcgtcaaata atcctgggta agtaaccgcg attttttctt ttgaacctac
     3481 atgttcagga tccatagaga tgcgtgtttg atctcctact tcaaatttga tgtatcctgc
     3541 acgaccaaaa tcagcttctg ttgtgccttg aacagttgta cggatttcag ctccttttgt
     3601 atctaaaaga ataccgacat cttttcctgt ctttttaact gcttcacgga ccatagtcat
     3661 acgtgataat tgttcttcat ggtcaccatg agaaaaatta aagcggaaga catttgcccc
     3721 agattcaatc aattgagaaa taatttctac tgagttactt gctggtccta atgtactaac
     3781 gattttggtt tttttcattt aaaaaactct cccattcaat tttgtttatt taaagctgta
     3841 cacagcttaa atagcttggt ttctttcact cttaaaatga aagtgaatta tttagatcat
     3901 atagtgataa gtctggttta tgtttgttgt tttcaagtgt atcaatgatg tcagacgcaa
     3961 cgatttcgtt gtcatggata ccgacacata atccaccttt tccttcttga agcaattcga
     4021 cagcgtaagc accgaattta cttgccaaca cgcggtcgcg tgcgcttggt gctccaccac
     4081 ggacaacgtg tcccaagata gatacacgtg tatgatagtc accaaattct gaaagtttct
     4141 cagcgaattc atttccgccc attacacctt cagccaagat gatcaagcaa tgtttcttcc
     4201 cgcgatcgcg gccttcttgg atttttttag caactgaagc catatcaaaa tcatgttctg
     4261 ggatgatgat ttcatccgct ccgccagcca cacctgacca taaagcgatg tctcctgcat
     4321 tgcgtcccat tacttcgata acgaatgtac gaacatgaga agtcgctgtg tcacgaatac
     4381 ggtcaattga ttctagtact gtattgattg ctgtatcaaa accgattgtg aaatcagtcc
     4441 caggaatatc attatcgatt gttccaggaa tacctactgc tgggaaaccg cgttttgtca
     4501 aagccattgc gccatgataa gagccgtctc ctccgataac cactagacct tcgattccga
     4561 attttttcaa ttgttcgatt ccttttaatt gaccttcttc agttgcaaat tctggataac
     4621 gtgcagaata caagaatgta ccaccacgtt ggatcttgtc acctacatct gccacatcaa
     4681 gacgacgaat atctccagca actaaaccgg caaaaccata attgatcccg tatacttcca
     4741 gtccttcgta aataccttta cgaacaacgg cacgaacagc tgcattcatt ccaggtgcgt
     4801 ctccgccact ggtcaaaatt ccgatgcgtt tcataataaa cattcacctc attaaaatac
     4861 tttatcctaa gtatgactta ggtttacaac catttttgcg ttaaccacga ctaacattct
     4921 aacattattt ttctcacttg tcttgattta cggataaaaa aatgaaaaaa aatgaaagca
     4981 agtagtattt tttaccgtaa gttatttgaa aaccacatta tcttcgccaa gcagataaat
     5041 aagttgcccc tttatactct tgctgtcatc cacccaataa gcatctgaca gaactacttt
     5101 tcgttgcgtt ttttcgtgat acataactac tggtatatat cctgggtgtt tctgaaaaat
     5161 cacttgtaat tgtttcatta tctcgggatc ttcccgttct tctgtaatac gcaaatagca
     5221 agtttgtgaa ggatactggg cttctaactg gttaggatca gcaaagcttt ctccaattag
     5281 ttgcagttcc tgattatatt tgctgatttc gctccgccct tgaacaaaga tcactcgatc
     5341 aacggcaaac aaattacgat atttacgata aagagttgga aaaactgtga cagaaatttc
     5401 tccactactg tcggttcctt caacaaaggc catcagttct cctttttttg tccgaatttc
     5461 tctaacttcc ttgatcatca ctaataaatt gactggttga ttagggacga tatctgtaat
     5521 cagctgaact tgtttagcta aacgaagacg atcaaaccct tctgcaggat gacctgacaa
     5581 ataaatacct aagtactcct cttccagctt caagcgttct tctagtgtat agtcagcgac
     5641 ttcttcttct tttaatgcca tgattcccag caagtcaaga cttccaccac tgtaaacgat
     5701 attttggatt tttccttcga gatcaagcat caattgtttc ctgttaggag ataattcatc
     5761 aaaaactcct actgctgtca gtgattgcag taactctaat ttcagccaac gcttatcgat
     5821 ccgtatgagg aattgatcca ctgactggaa cgggccattt tgttttcttt cgtttaatat
     5881 atcttctaca aaatcacgcc gaataccttt tatcgctgtc agtccgaatc tgatttcttc
     5941 cttattgacc aactcaaaac tggaattact ttgattaatg gacggcgagg aaagtttgag
     6001 tttattttta cgtgcttctg caatatattc tttcaatttt gatgtgttat gccgaacaga
     6061 attcatcagg ctggtaaaga aagcacctgg atgatgggct tttagatacg ccatttggaa
     6121 tcccacgaat gaataagcaa atgcatgtga ccgattgaat ccatagtttg caaatttttc
     6181 gatatattca tatacggtcg ctgctgtttt ttccgaatat ccctgttgta atgctcctga
     6241 tacaaaatgc gacttttctt catctaatac gtcttttttc tttttactca ctgcccgtcg
     6301 cagaatatct gactgcccta atgtaaatcc agccatagtc gaggcgatct gcatgatttg
     6361 ttcctgatag acgatcactc catatgtgtt tttcaaaatc gggatcagtg aatcatctgg
     6421 gtagcgaatg gcttcttttc ctttcttcct ggcaatgaag gtatctatat tttgcatagg
     6481 gcctggtcga tacaatgcat tgactgcggc aatatcttcg atgttttctg gatctaatct
     6541 tcgtaaaacg ttccggatac cagcagattc aaattgaaat actcctgagg tttcgcctcg
     6601 ttgaaacaag agcagcgttt ttgcatcatt tagcgggatc tcttttaatc ggatctcata
     6661 cccttctact cgcttaacag ctttcaaagt aaaatcaata atcgataagt tgcgtagtcc
     6721 taaaaagtcc attttcaaaa gaccgattgc ttctacctca ttcatcgtat actgggtcag
     6781 aaaagcttca tcagaaccgc gttggagcgg aactagttca agtagattct tatcgctgat
     6841 aactacacct gctgcgtgag tcgaaacatg tcttggcaat ccttctaaaa tcactgcagt
     6901 tttgaataaa agttggtttt tttcgcttgc ctgaactaat tctactaatt gatgcgaagt
     6961 tttataagct tgggtcaatg tgattttcaa ttgattgggt attgcttttg accagcggtt
     7021 tgcttcactt tgcgataaac caaacactct agctgcatct ctaagaacca tttttgctgc
     7081 cattgtgcca aatgttgcga tttgtgccat atgatattgt ccatactttt ctcgaacata
     7141 attcaatact tcttcacgtc gattgtcagg aatatccaaa tcgatatctg gcatcgtaaa
     7201 gcgttcgggg tttaaaaagc gttcgaacag caaatcatat tctaatggat ccacatctgt
     7261 gatttctaac acataggcta ctaatgaacc cgcagcagaa ccacgacctg caccggtaac
     7321 gattttgttt ctatgagcaa aagccattac atcccatacg atcaagaaat aatcatcgaa
     7381 tcccatttga tggatgacag ataactcgta gtccaaacgt tcttggtatt cctttgtata
     7441 gtcagtgatt cggcgttcca cttgcgaata gcataactct cttaaatatt ctccagcttg
     7501 ttttccatta ggaactggat aatgcggaag taatttctga tggaactgga attcaaatga
     7561 aatcgattca gctaaacgct gggcgcctat tacagcttgg gaaagacccg ctttttcgaa
     7621 tcgtttgatc atttcttgtt ctgaaagaag atagacattt gctgttagtg gtaaagatgc
     7681 agataaattt tctaaaggta tttggcttcc ctctttgata tgtttcatca cttcaagtgc
     7741 aaaaagttct tcttgttgta aactagcgat gggatgtaat gcacaaagcg aataattttc
     7801 ttttatcaca tactgatacc attcaggcaa ttgatcaggc gtgttttctg tcaagccgat
     7861 ataaaaattt ctagtaaaaa cattttcaag taaaaactgc caatgaccga aaaagttatc
     7921 ctctttattg aaagcctcag aaacagaatg atttgccgga acaacaaacg ctagatggtc
     7981 ggtttctgtc atttctgcaa gttccaattt ttcttggatc atttttcggc tggaaagttt
     8041 catcagctgc tgataaccta tttcatcttt tgcgtacgca agcaagccat aatttttttc
     8101 ttcataagta taactaagat gtaatccaat gattggctgt actccttctt ctacacaaat
     8161 acgatagaat tcaggtgcac cgtataagac atctttatcc gttatggcta atgaagtgta
     8221 gccttgtttt tttgcttctt gtacatattc tcgaatacgt atcgtacttt gtaaaagaga
     8281 ataagaagta attgtataaa gttgtgggaa aaacatcttg cattccgcct tttttttcgt
     8341 taaaattcac tagcgttaaa aggtttgatc cttttacttt cattaagata gcaggcgctg
     8401 aagttgatta ttccacttca tttgcttgct tgtaatctgt aggaatgagt tctttcgcaa
     8461 gaactcaaat tttattgaga tttggtctcg tttctttaca ttcaaagaaa atctggtaaa
     8521 attaagatag aaaagaggtg ttctttatgc gatatatcgt tacattattc tgggctgtcg
     8581 ttctaggtca agtagtcggt tatattggtg ctgcattaac aagcggaaca tatgatttta
     8641 ctttgacaac aatcatttca ttcattgcgg gtgtcattat ccttttgatt ggtgcagttg
     8701 cgccaagaaa agaaacctct gcccattcgt aaaaaaacag ccaagagctt gagatttctc
     8761 aagctctttt ttattttcta ctcctcacca ccattataat ctgctgcgaa gaactttacg
     8821 aaagttgaat aaagaaagaa gaatatttga cagaacaaac aaacttgtca caataaaaac
     8881 agcactgtaa ttataagcat gcgcgactgt cgatcctagc atgggaccta aaacttgtcc
     8941 aaagttgcta aacatctgat tgtagctata gattcggctg actccttctt gaggcgtaat
     9001 cttactgatc agtgtattga cagaaggcat caaagcgcca gttgaaaagc ctaaaataaa
     9061 gcgaagtata cctaattgga gcggtgtagt gacgaatgcc ataggtaaat aacagcaaaa
     9121 tgataaaatg agtcctccaa ttagaacttt ttgattccca atcttatccc ctagttttcc
     9181 tagtttcggt gaagaaaaga cagcggaaac accagctatc gaaacaatca agccgctgac
     9241 aaaaaggata ttttctgtac ttccgctcaa ttcacgaata tataaggtca aaatagggct
     9301 gatcgtagtg attcctatct gtaaaatcaa ggtcgtaatg aagagaccga tcaaaataga
     9361 gagatgatcc atttttgaaa aaatttcttt ggtgcttatc agatcttttt tctcgattgg
     9421 atggaaatct tctttgacta agaaaatggt caataccgtt gtgatcatca acaaagcccc
     9481 tgtgatcaag aatacatttt ccataccaaa ccactgagcc agtgcaccgc ccattgaagg
     9541 tccgatcaga tttccagcaa tcgctccggt agacaatgtt cctaacgccc atccgctctt
     9601 ttctctaggt gcctgtgaag caatcatcgc tgtggcattt ggaatatatc cagacaaaat
     9661 cccattccaa aaccgcatga tcaaaagcca atacgcgttt ggtacaaaag ccaaagatcc
     9721 cattgttaat gtcatccctg ctgctgcacg gatcatcatg agttttcggc cttttcgatc
     9781 agctagattt ccccagattg gtgcaaccac ggcagatgca aaagcagtca cagagattgc
     9841 tagtcccgaa aacaattcga tttgatcttt tggtgttcct agttgctcaa cataaactgg
     9901 tatgaatggc ataactaaac taatacttgc accagtgaaa aaacagccaa tccacgcaat
     9961 cactaaattt tttctccaat taatctccat ctatcatccc tctttcgtct cttttatcat
    10021 acctattttc gaataaacaa gcaacgatct cgccagtaaa aagagaaaaa tcccgcaaag
    10081 gtcattttat atgtaacgtt ctttttatgt aaaacaaaaa gagatcagaa caaatactgt
    10141 tccaatccct tctctttagt taaattgttg ctagaatgat gaagttgata atgaataaaa
    10201 tatcaacgat ccacaaagca acagaaactt gattgtattt tcctttgatt actttcacaa
    10261 ttgtatagaa aataaatcct gctgcaatcc cataggaaat gctatagcac aatcccataa
    10321 agatcgatgc aaagaaggcc ggtaaagctt cttccatatc tagccatttg atgtctgcaa
    10381 aagaagccat catcattact ccaactaaaa tcaatgctgg cgcagttgct tgatttggta
    10441 caatggcgat cagtggagag aataaactac ttaatgcgaa tagcactgcc actactactg
    10501 aagtcaaacc agtacgtcca ccggccccga tcccagctgc agattcgaca taagttgttg
    10561 tattcgatgt accaaagata gcccccacag aagtagcgat cgcatcggca aatagtgctt
    10621 tatccatttt tgttttgaac ccacgaccat cttccaacgc gatctcgtct tcttttgaga
    10681 aaatacctgt gcggcgtcct gtaccgataa atgttccgat cgtatcgaaa gtatcagata
    10741 aactgaatgc gatgatcgtc atcaatactt gaggaatctt ggaagaatca ctgaataaag
    10801 attgcatgcc ttcagaacca aatgctgcac cgaaagttgt tcctaattct ttaaatgaat
    10861 tacctaacga attcgtttgc caatcaatgg aacttaaatc aacaacaccc ataaaaatac
    10921 caaggactgt ggtcgctacg ataccgataa gaatagcccc acggacattt tttacaacta
    10981 aaatggctgt cagtaccaaa ccaatcacag ccaataagat aggagcgttg tcaaagttgg
    11041 ctaacgcagg gacgattcca ccatttatcg taacatttgt cgcttttccg ccttcaacga
    11101 cagagctcga aatagctgac tggtctgctg aaaaagataa gaatcctgca tttttgattc
    11161 cgacatacgc aacgaaaata ccgatcccgc caccaatcgc atgttgaaga ctttcgggaa
    11221 tcgcccgaat aatcattttt cgaatatttg tgacagtaat aaaaatattg attaatccgc
    11281 aaataaacac cattgccaag gcttgttgcc aagaataacc aagcccaaaa acgaccgtaa
    11341 aagtgaaaaa tgcgttcaat cccataccag gtgcctgagc atatggtaca tttgcgaaca
    11401 atcccattac cagcgtacca ataatcgatg caatgattgt cgctagaaat actgcttgga
    11461 agggcatacc tgatgctgac aaaatcgtcg gatttacgaa taagatataa ctcatggcaa
    11521 agaatgtcgt tactcccgcc attatttcag ttgatacatt tgtattgttt ttctttaaac
    11581 cgaaaaactt ttccataaaa agttccactc cctgaatttt tttctgatgg aaaactataa
    11641 taataaaaaa taagtaaaat agggcaaatc catcgaacaa tttcaaatta tatagacgtt
    11701 tcattcgctt ttcaacgttt ttttaacaaa aaaagcgaaa ataatactta acgttcgtgt
    11761 ttagcttatg tttagctatt tatatagcca taactgtagt ttttgttagg aatagctgat
    11821 tgctcttgtt aattacctaa aatatgctag actaaaacaa atgctagttg aggaaggaag
    11881 gacccttatt gaataaaaaa ttaattgcca tcgatctgga cggaactacc ctcaatcaag
    11941 attcgatgat tacatctaaa acaaaagaga ctctaaaaaa agcaatcaat gccggtcatc
    12001 atgtcagtat tgctacagga cgcccattcc gaatgagcca tcagttttac caacaattag
    12061 aattaacaac accgatggtt aattttaacg gcgcattagt acacatccct aatcagcact
    12121 gggatggtga aagagaaacg ttgatcaatc gtgaaatcgc ttttgaaatc ttatcgcaaa
    12181 aaaagcagct aaatttagat tttatcgctg ctgaaaatcg tgatactttt tttattgaca
    12241 gttttgattt ctttgatgaa aaaatttttg cttcttctcg tccaggagag aagaatttgc
    12301 tttctcctaa aaatttgacg acaaatccta catctttgct tgtccgaaca gacaaacgtt
    12361 ttgcaggagc tgtatctgct gaattaacac gtcaatttgg cagttatgtc gatgttcgga
    12421 catggggtgg acctactgcc atcttagaga ttgtttcaaa aggaatccaa aaagcaaaag
    12481 gcgtgcaaga gattgctaac tacctgtcta tcgatcaaaa agacgtcatt gcctttggtg
    12541 acgagcataa tgatttggaa ttgttggatt atgcaggttg gggagtagct atggctaacg
    12601 gtactgacca actcaaaggc attgcaaatg atgtcactcc tttgagcaat caggaagacg
    12661 gtttagctgt ttatctggaa aaactactta aactataata gagaattaga ttccacaaaa
    12721 aagaggttgt gacaattttt gtcacaacct tttttgccga gtaaacggtg ttcaaaagcc
    12781 agtttctcgg tatgaagtca aatttaagca aaaatgtgag aagctatttt cacaaaattt
    12841 ttcttcatac tcgaaactaa gcggcttttt cacgacctct tttttatttt gccatgaaca
    12901 tatcataata cgcgtccatt atttctttag caatcgtcaa gtttatgtgg tcttgttcgt
    12961 ctaataagtt cggcaagaca acactgatgg caatttccgg attgtctgtt ggtccgtatg
    13021 ccacgatatt actattgact gtcgcaatat ctggatgacc ttccgcaacc gtttctgcag
    13081 tccctgtttt tgcggaaagg tccattttcg cactggctaa tggtttggct gttgtgtaag
    13141 gatcggtacc atggacaact tggtggaatc cttcacggag gatcgccata ttttctgcag
    13201 aaatattgac cgtattttct actgttgtgc caatttcttt cttcacttca cccaagtttc
    13261 cattttcgtc attgccatag atcgctttga ctaggtgcgg ctgtactcgt ttcccgccat
    13321 tagcgactgt tgaagcatat tgagctaatt ggattggtgt atatgtgtca aactgtccaa
    13381 atgccaaatc ggtaaagtta cctggagcat accattcttt gccattatcc gcattgaact
    13441 tcttcatata atcaacagaa cgtgagatcc caggagattc attcggcaaa tcgatcccag
    13501 tcgttgtacc aagaccaaac tctttgaaag agtctctcaa ttgctgataa gctttagctt
    13561 cttcatctaa actaggtagt cccattccag gtgtatagtc tagtcctaac atctttaacg
    13621 ccactttgat catatacgta ttagaagaca attccgatgc tttgactgca tcaagagcaa
    13681 cttgtccgct tcgattaaag acagagcttt tttctgaagc accttgcaga cgaatcggct
    13741 catcaatcaa aacttgattt ccgctgatcg cgttacttgc ccagcctgct gtcaaagtac
    13801 cagccttgac tacagaccct ggatcaaagg cgctagtaat cgtgcctaaa gcattctcgg
    13861 tgatttcttt ggaaccttgt tcatgactga aaccagtcat tgctagcact tctcctgtct
    13921 gaggattcat agccactgca taagcaccag gcgaatactg tgctttgccg ttgttgatca
    13981 atgtttgata attccttttc aaaatttctt ctacttttga ttggaattct gcattcatag
    14041 ataacattaa attagaacct ttttccccag agaagatttc tttttgattc gaaacatttc
    14101 cttcattatc aagggaaact tcatattggg ttttggttcc ttgcaggaca tcttcatatt
    14161 gtttttccaa ataactttgt cctacacggt cattccgaga ataacctttt gctaggtatt
    14221 tctctgcttc atctgctgga agtccttgct tttcagtcgt cacactgcca agaatacttt
    14281 tcagtgaact tgctgcatta tattctcgtg tccagtctgt gccagtcgaa actcctggaa
    14341 gttcagaagc gcgttctgcc acaacagcta actcttgatc agtaacacca gagtttttga
    14401 tatagacagt gtttaattca tatgcactat tcatccgttt aaagatggta gcaattttta
    14461 attgctcctc gtttaaatta atctcatcag ctgtgacttt attgaccatc gcactatatt
    14521 gttcgctgtt ccctaattgc ttttcttttg ccgaaagtct ttttgtggct tctttcaaat
    14581 gtttgggatc agccagccaa aaatcttttt tatctctatc tgtcagattt tcatctaccg
    14641 gaacatcgat cagcgagttc agcttcgttg cgatttcaag caaatcttta gccgtaactt
    14701 gtgttcctct cgtatatgtg atggcctgat tcgctttatt cgtaactaaa gcttttcctg
    14761 tggagtcgta gatcattccg cgaggagtac tttcttggac cgtaatcgta gaagtagact
    14821 tcactcgcgc ctccatctct tcgccgttca cgatctgcaa ataacccaat ctagcaatca
    14881 acgcaacaaa taacgtaaat ataatgaaaa aaagaaaatt taagcgaaaa ggaacatggg
    14941 accggcgaaa cgttttgttc ttaggttctt gtgcaccttt tcttattttt tctaaccaag
    15001 aagtatttaa tatttttttc ataaaatctt tcatcatttc ctatccttcc gcctatttac
    15061 attcatgctt cattgtaccc aaaaacttct taataaaaaa gaaaaaatgg gcggagcaag
    15121 aaattcttta cctaatttca agataaaatc aactttttgt ttcacagcaa tcacttaaag
    15181 ttacatatcc aactattttt ttcattaaaa aataaactta tttttgaaaa ttatgttttc
    15241 ttaagtcgtg aaacactttg atggatcatt tatttgtgga aaactacgtt ttgttattct
    15301 aaaaaactta tataaaaaat agtaaggttt ttatttcgaa tccataaaat attcttggat
    15361 tgcttctcgt gtttttttca ctttttcgct aagcttttcg tttttagcca tatagaaata
    15421 aaaaatgata tcgatcgtag caaattgggc caaaagtgaa ttagttgccg cacttcgatt
    15481 cgtgatttct tttggtctag atgtttgtac gagtacatcg gctatcttgc taagcgggtt
    15541 atttccaaat tgcgtcaacg caatgatttc gatattcatg cttttcgcca gctcggctaa
    15601 tgcgactaca tctgcacttc tacctgagtt tgaaacaagc caaagcactt tctttttctc
    15661 attgctgaca agttgcggga gcaagacgtg gatatctttt tcaaaaatga ttggcttacc
    15721 gacacgagac catttttgca gaatatcttc tactactaaa gaagaggcgc caaccccata
    15781 taaaaaaaca gtctctgccg attccaaaca ctctacgact ttttggatcg tttcttcttc
    15841 tagaatatct actgtttctt ttatcgctac ttgtgcattg ttaccaagtt tgtttttgat
    15901 agagtaaaag gactcatttg cttctatatc actaaaacct tcatcgattc cagtctgtag
    15961 ttctgttgaa atcgtgattt tgaagtccgt cagactttga aaaccgattt ttttggaaaa
    16021 acgtacaact gtcggcgcac tcaacccgga agcttctgct aattcattag ctgtcattgt
    16081 agggaccttc tcaatattac cgataatgta gttggccaac tttttttctg ctgaagaata
    16141 atcttccatc atactttcaa tacgactaat tacgctcata agttcctcca cccttttaat
    16201 gatagtctat gtaagtatac catatcagac ccttattcac ggtcgtatac tggataaaaa
    16261 acaaaaaaac aatccgccca acagaatatc ttatcccatc aatcccacag attctattga
    16321 gcatctgtgt ctttgaggaa tacctgttat ctattgttcg gattgctttc tatctactac
    16381 ttttttacag gaaatttacc tattagtttt ctctgctgta atttttgact tctgcttcca
    16441 tagcatcaat aaagatattc aaatcttcta cagctgtttc tttacttcca taacgacgta
    16501 cgttcactgt tgcatcttcc aattccttgt ctccaacaac taattggtaa gggatctttt
    16561 gtgtttgaga ggcacgtatc ttatagccca ttttttcatt acgatcatca acttctacac
    16621 gcaacccctt catttgcaaa cgttctttga tttcataagc ataatcgcca tgtgcatcaa
    16681 cagaaacagg gatgattgtt gcttgtatag gtgccaacca tgttggaaaa gcgcctttgt
    16741 atacttctgt taaataagcg acaaaacgtt ccattgtaga aacaattccg cggtggataa
    16801 ctactggacg atgcgtattt tccccgtctt ctccaacata tgtcaaatca aagcgctctg
    16861 gcaataagaa gtctaattgt atagttgata atgtttcttc tgtaccaaga gctgttttga
    16921 cttgaacatc tagttttggt ccgtaaaagg ctgcctcgcc ttctgcttca aagtaatcta
    16981 gttctaattc atccatagcg gctttcagca ttgcttgggc tttttcccac attgcgtcat
    17041 catcaaaata tttatctgta ttgtttggat cgcgatagct caagcggaaa cgataatctg
    17101 taatattgaa gtcagcatat actgccacca tcaattcaag cgtacgttta aattcatctt
    17161 tgatttgatc aggacgaaca aatgtatgac catcattcaa cgtcatttct cgtacacgtt
    17221 gtaaacctga caaagcacct gatttttcat agcgatgcat cattcctaat tcagcgatac
    17281 gaattggtaa ttcacgataa gaatggatcg tgtttttgta gaccatcatg tgatgagggc
    17341 agttcattgg gcgaagaaca agcatttcgc catctcccat atccattggc gggaacatgt
    17401 cttcttgata atgatcccag tgtccagatg ttttgtacaa ctcaacatct cccattattg
    17461 gtgtatatac atgttggtaa cctagactaa cttctttgtc tacgatataa cgttcgatcg
    17521 tgcgtcggat tgttgcccct tttggaagcc agaatggcaa accagaacct acttctgggg
    17581 aaaccatgaa caagtcaagt tcttttccta gtttacgatg gtctctttct tttgcttctt
    17641 cacggagacg gatatattct ttcaaagctt tcttgtcaaa aaaggctgtc ccgtatacac
    17701 gttgcatcat ttgattgttt gagtttccac gccaataagc acctgccact gataataatt
    17761 taaatacttg tatacggcca gtggatggaa catgtggtcc acgacacaaa tcgatgaatt
    17821 cgccttgttg ataagcagta atcacttctt cttctggcaa ttcactaatc agttctactt
    17881 tgtacggatc acttgcaaaa atttctaatg cttcctgttt tgaaagaaca cggcgttcga
    17941 tcggcagatt ttctttgacg attttcatca tttctgcttc gattgccggc aaatcttctg
    18001 cagttacttg gttttgtcca ttatctgtat cgtagtaaaa ccctgaatcg atagctggtc
    18061 caacgccaaa gtggatattt ggatagaggc gacgcatggc ttgggccatc aaatgagctg
    18121 ctgaatgacg gactaagcca agtgcatctt catggtctgg tgtgatgatc tcaatacttg
    18181 catcttcctc gattggacga gtcaaatcaa cgagttttcc gttcacttta ccagctaaag
    18241 ctttttttgc taagcttttt gaaatgcttt cagcaattgc caatgttgtt gttccagact
    18301 caaattcttt gactgcacca tctggaaaag taatttttat cataatagtt tcctccttga
    18361 aatgttttga ttgatcagat catcaagctg aaaaacaaaa aaatcctagc atctcttgaa
    18421 aagagatact aggacgaaaa gttcgtggtt ccacctaatg ttcaaacgca aatgcgttcc
    18481 tcaagcgttg taacggtccg accgcccttg cttcaacaag ggtttcgaaa gtggtcatcc
    18541 tttggttttc tcctggaaaa gtttcagcct agcttttcct ctcttatcga agactctcaa
    18601 attcagttgg ctttctcatc aatcaattat gtgtttattt aaccactaat aaatagaaaa
    18661 atcaagtggg aaactaaact tattttttcc attccccatt tacaccgtat gttccttttt
    18721 tcatctcatt gatgatgaca tggatgtgtt cttttggtgc ctgcgtgttt ttatgaacag
    18781 cttccgtgat atctttcatc atattttcta attgttccgg actgcgacct tctactaatt
    18841 cgacatgtac gaatggcata atgctctctc ctctttctga tcgttctttt ttcaactcga
    18901 ttctatcata ctatgtttgt cttgggtact gaatcaggaa aaatggctgg atcttttttt
    18961 gctctcaagg cactcaaaat agagaccgta tccacgactt cttgcaaaac agctccgaat
    19021 aatgcgggga ttagtcccgt acttgcaatt aacatcaaaa aaatacaaat aaagatgcca
    19081 atcagtacaa actgtttcgc tattctcatc gtatctcttg aaatcactac tgcttttgct
    19141 acacgcaaga gatcatcttt caagatgacc gcatctgcac tttcactagc agctgtagaa
    19201 ccatgagccc ccattgcaat accgatatct gcagcagcaa gtgctggtgc gtcattcacg
    19261 ccgtctccta ccatcgcaac aggtctttga tctttaggga tactttctaa aatggtcagt
    19321 ttatcttgag gcaagctacg ggcatgtaca gaatctaatt ggactttttc tgcaatcgtt
    19381 tgagcaatgg cagatccatc cccggtgatc atcatcaaat ttttcacatc aagttttctt
    19441 agctccttga ttgtctttgc tgcttctggg cgaatctgat ccgaaaatag gatcgttcct
    19501 gcaaaagatc gatcaattgt tacatagatt gctgtattgg acgtttctat ttcttcagct
    19561 gaaacaaaag aggcacgtcc aatctttact tcatgattat tgactactgc ttggattcct
    19621 tgaccggtca cttctttcag ttgactaaca ggatacagtt ggctgttttt cacgttgttc
    19681 actaacgaac gagctaagat atggctagat tcctgttctg cactagctgc atacagaagt
    19741 agctcttctt tttttattcc attgactggc tgaatcgcct ctacttccaa tatccctttg
    19801 gtaagcgttc ctgttttatc aaaagcaatc gtttttgtac gtgcgagctt ttcaatcgtt
    19861 gttccagttt ttacaacgat cccgttttta cttgaacggc tcattcctgc aactaaagca
    19921 atgggcgcag ctagaatcag tggacaaggt gatgccacta ccagtacctc agcaaatcgt
    19981 aaagggtctt ttgagaacca ccaagaaata ccaccgatca aataagcaat caacgtgaaa
    20041 gggactgcat aacgatcagc taaacggaca aatcgggcag gcttttcttt tgattcttcg
    20101 actagtttaa taatcatttg atactggctg tctgcggcac gtttttcagc gatcatttgg
    20161 atcgatccgt ctccatttaa agaccctgac ataatctgat ctccaggttt cttggtttcc
    20221 gggcgggact cacctgtcaa agaagattca tcgaccgaag attctccttt ggtcactcga
    20281 ccatctgcgg gtacaagttc gccaggcttg actagtaact ggtcatcaat atttatttca
    20341 tcgattacta tatcctgcaa ttttccttct ttgaatcgat gggcaattct tggggtgtta
    20401 tctaacaaag actgcagttc tttacccgct cgtttattcg cgtaatcctc tagactatct
    20461 ccgcccgtaa gcatgatcaa tatcatcaaa ctagcccagt attctttgac ggctaatgtt
    20521 gcaaggattg cggtaatcgc taatacatct acgccatatc ttcctgaacg taacgtcttg
    20581 atcatttcca aaaacatcaa gaaggcgaga atccctccag taaatgcgac aatcgcaaat
    20641 gcaagggccg gctggtgaaa aacaaattca cttaataaag ctatcccacc aataagcaaa
    20701 gtaagtaaaa attttttgaa atgtgtcatt gttttttctc ctcttttatg tgacttagag
    20761 aggttagtaa taaatttcca gctgcctctt tcatcttaag catagtcctt gactagcact
    20821 ttttaaaaca ataggcctta attgaaaaca actatcacta tcagcgtttc caaaattcat
    20881 cagttctaca aacaaaaata ttcagcaagg attacttttt cgattcatca gttaaaaagt
    20941 accttttttc gaaaaactat gctatacttt taattcgtta tttacggcgg aaggagcaaa
    21001 catgcgatga atgagaaaca actagaacaa acgcacgtgg atgaaacgat cgaactaatc
    21061 cagatcgaac aaaatatgct ggatacaaaa caacaagaat tgactcagga aatgaatcat
    21121 tcgacaaaag acacagctaa tcacaagatt cgagctggtt ccaatgaagc tttttatgaa
    21181 tctgctgttg aatatcgcca acatgagcag gaattgcttt tgaaatacca tactcttgaa
    21241 gcacagcaaa aacgcctgca aacgttgtct gtcatgaaag atagtcctta ttttgcccgt
    21301 atcgacttta aagaagaccg tgaaacagaa acattatatc taggtatcgc ttctttaaga
    21361 gatctggcag aagaaacaat cgttattgac tggcgcgcac caattgccaa tctttattat
    21421 gaaggtgaga ttggtcccgc attttatgaa actgaaacag atagaataga tgtcgatctg
    21481 cagttgaaac gacaatttaa aatccaagaa ggacgtattt tatctatggt agatacgtcg
    21541 gaagtaatca atgatgactt tttgctagag atattggatg aatcatcaag caaccatatg
    21601 aaaaacatcg tctctacgat acaaaaagca caaaatgcaa tcattcggga cacaacaagt
    21661 aaagtaatgc tgattgaagg aatcgccgga agtggaaaga catccgcttt gcttcaacgt
    21721 attgcttttc tgttgtatca taatcgcaag tggctcgagg ctgaaaacgt tcttctattt
    21781 tcacccaacc atttgttttc tgattacatc tcgactgtat tgccttcatt aggtgaaagc
    21841 ggcgtgccta cacagacatt caaaaattat ttggtgcagc tgctgccaga gttttcttta
    21901 ctagatgaac agcaacaaga aagtggtttt ttgctagggg aaaaagatcc gatacaagtg
    21961 atgaaaagcg gattgacctt agtcgatcag attgatcgct atatccaagg catcacaaac
    22021 tacggtccct tgttccgtga tatgaaaata aatggccgta cgatcctatc aaaggaatcg
    22081 attcgccaat ggtataaaga aacaaatgaa caattacctt tacatcatag actttctcta
    22141 ttacaaacga agctcctgaa aaaattaggc ggtctgcaaa aagacgaaac acgtcagcaa
    22201 tgggtcaaag atctggcgga agaacagctc caagaactat acgcaacaga tccaaatctt
    22261 gaatatacag aacaaaagga gcgttcatta cgtaaaaaac tggccaacca aatcgtacgt
    22321 aaaagattcc gtcgaatcca tcgagggatc atgaattatc aatttgtcaa tataacgaaa
    22381 caatatctcc actttctaca aactgtgcca ctttctcttc taacacgaca taaaatcagc
    22441 gagaccaggt ggcaggaaca tttgacaact gttcgtacac acttgcgtca aagagaattg
    22501 cgtcaagagg atgctgtact attcttttta ctgatgcgcc gaacatatcc agtgacggtt
    22561 acacacaaag ctcgctatat ctttattgat gaaatgcagg atttcgcacc atcacaagtg
    22621 gcattgctgc aagccttgtt cccaaaagca aatttgactt tctgtggaga tctaaatcaa
    22681 aatgtctttg gaaatgaaac gatcgttgga tcattggaag accttttcgt ggaccgtgaa
    22741 gtcactcgtt tccaattaac gacaagctat cgctccacaa aagaaatcac tgattttgct
    22801 aatcatttta ttgtgaaaga acatcaagta gaaacaacag caagaaaagg agaccttcct
    22861 ttgctcatcc aaggaacaac agatgatatc aaattgaatt ggttagcaga taccattcga
    22921 acgactcagg gaaaagcccg gtattggcgt acagcaatca tagctaaaac acaagaagaa
    22981 tgcgaagctc tttatgctca actgccagac gagttgaaac aacaagtcca gctgatttta
    23041 aatgagagtg actttatgaa gcgttccatt attttacttc cagccttttt agcaaaaggt
    23101 ctggagtttg accgagtttt cttgtgggat gtagatgcag aacatttttc ttctcagcaa
    23161 gacaaattga tcctttacac catgtgtaca cgtgcgatgc atgaattgac cctttttacc
    23221 tccaataatg aaagtccttt gttaaacaat atggatattt catcttatga gaaaaaagta
    23281 ctgtaagtaa aaagacaact gctatcatta atgttagcag ttgtcttttt atttacaata
    23341 ataattgcag aaaaagtaat tcaatcattt aaggtcattt attctatata taaatccaaa
    23401 tctgtttcag gatattttaa tttgacaagc gaaataatca ttttcagttc ttccatgttt
    23461 tctggatatt ctgggtcaaa taccttgcta tgacggccaa tcccgccatt gtcgatcaat
    23521 cggtaaattc gattccattc aatgaattgg tcaattgatt ggaaattgct gattggatag
    23581 ccgccacaat ccaaaatctc tgatacacga aatgctaggt atgcactatc gatcacttta
    23641 ttttttttcg tgtctatctt ctcatttctt tcgataagaa ttttttcagg acgatgtttc
    23701 aagctccact ctaatagtag aaagaaagcc tccatccgat actcttcttc aaataaccga
    23761 aaggctgaat cagaacgacg aaaaagcagc ggaatcagat aattttgtct ataaatcagc
    23821 attggtgcgc ggtccaccat acactctaaa taacggttca gataccctgt accgacatag
    23881 tttcctaatc gatagccttc aacgccgaat cttgcgtatt tttgcgctaa ttttgaacaa
    23941 tcagttacgt tcacagctaa ctcttctact ttgcggtaac cgcttaagat acgttcaaaa
    24001 ggttctaaag tgatttttgc ttccatattc ttccccgtcc atcttccaca tacttcatat
    24061 catttcacat gatacttatg ctctcatcat accacaggtt gaattagaaa agaaaataaa
    24121 tcacacaaaa aagcaagaca atctgttagt gagattgtct tgcttttcga aaaagactga
    24181 atacttttcg ttaaaactgg ttgcttagtc ttctaatgcc acattatgga acacatgctg
    24241 tacatcttct agatcttcca gtgcatcaat cattttttca aatgtttctt gatcttctgg
    24301 agatagtgtt acctcgtttt gagggatcat ttggatctca gcgattgaaa aatcagtgat
    24361 tcctttttct tttaatgctt cttgtatact atggaaatcc gctacttcac cgtaaacgat
    24421 gatttgtcct tcttcttcca ttacatcgcg aacatcgatg tctttttcca ttaggtattc
    24481 aaggatctcg tcagcgtctt ctcctgcaaa agcaaagatt gctgtattgt caaacatgta
    24541 agaaaccgct ccggaaacac ccatgttccc gccatttttc ccaaatgctg cccgtacgtc
    24601 tgctgctgtt cgattcacat tgttcgtcaa tgtatcaaca atcaccattg agccgcttgg
    24661 tccaaatcct tcatagcgca attcagagta tgtttcatct cctgcacctt ttgctttttc
    24721 gattgctcgg tcaataatat gttttggtac attataagtt ttagcgcgat caatgacgaa
    24781 acgtagtttt tggtttgcat gcggatcagg atcacctgat tttgctgccg cgtagatttc
    24841 aatcccaaat tttgcataaa tccggctatt attagcatct ttagcagttt tctttgctac
    24901 gatatttgcc catttacgtc ccatattttc acttcgcttt ctgatttgat agtttcataa
    24961 cgcaaaaacg tcctgttcca ttatacttgt gaatcacgat tctgtgaagc tttttttctt
    25021 tcttccttca ttcttctcat ttttagtcaa ttatctatac tcggattggg atttgcccga
    25081 aattctgttc cggaatattg cctcccaatt gatagatttg atcacttcta actaacagtt
    25141 ccgcttcttg tgcctctttt tttccgattc gggaataaat agaaatctct tttttttctt
    25201 ttaagaatct tcttccagca tcggtaaatc caagtagtcg aagataattt ttattttgtt
    25261 ggacaggaat ctcttgcttt ttgatattca gcaagacata acaagataat cgttggatcc
    25321 gtgtccatgt atatcttttt gtttttacct ttgacacaaa atcctcaaaa ctatcagcag
    25381 ttgcagctgc tgttttcatg cgcgattcta ttccttcggt catctgatag atatctgtca
    25441 gttccagcaa agtagaagat aacaaccgat aacgcaaata cggccaataa gattcccaag
    25501 tctgcagcga acaagttgaa agatcttctt ctgtctgagg cggcacaagt ccagctattc
    25561 tttttccttc ttctaacgca tggcgaatgg ctgttgcact ggctatcctc tgatctgtga
    25621 tgattttttc atgatagcct gcacttttac gtcggatcgg atgtaattcc atagggtgga
    25681 catacttggc attttccttt gcataactta atcccaagat atgatttggc gaagaaaaat
    25741 caagcgtaat atcgggatac agactgcgaa aaacctcagt cattttttgc ggataactat
    25801 acgtttgatc agacagttct tgaaatgcct cttctatcct atcttgattc tcttggacaa
    25861 agcgtccgaa actgctgtaa tcaaacgaag tctcttcttc tgttccaaaa cacaaactgt
    25921 cacagtccag tgtttgcaag atttttactg cacctttagc aaaatagtca gctgactgaa
    25981 ccgcccattc gacgggaagc tccactacta aatccacacc attttgtaaa gcttcattcg
    26041 cgcgatgcca tttatcgatg atagccggtt cgcctctttg caaaaaattc ccgctcatta
    26101 cagcaatgac gacctctgct cctgttattt ttcgtgccat ttccacatga tagcgatgtc
    26161 cattgtgaaa aggattgtac tctacgataa tcccgcagct tttcatgcgc atcctccttc
    26221 atagttatcg ataaaaaaga aatagagaca agtaaaaaaa ggcaaaaatc ggaaaaaata
    26281 cccgaactat ataaactatt ctcgcaaaca caatacttct gcgacgaaaa gctgcactgc
    26341 aagagcaatg cctatatcgt tcggatatat aatttatgtt gaagatttat tcttttcttg
    26401 ttaactcgag caggcaaaac cgctagtctt tgtatgctac aaagaaccag cgctttgatt
    26461 tctctgatgc tgcttcgtct gtaaaatcag aaaatgcttc gactttcgaa aagccgctgt
    26521 tttccagcat tcttaaataa ctttccaatg gataggtacg ctcttgatgt agttcatctt
    26581 cacgaataaa tcgaccagac ccttcttgtt cttcaacgaa aaaggtaaga aaatgttcga
    26641 tgctgtgttt ctcgcttcct ggataactat cccacaaaaa agcaaaatta tccccttgat
    26701 aatgatagct atattctgga aaaacctcat ctacttgata ggtggagtgt acgtcaaata
    26761 aaaatcggcc attttcttct aacgcttgat agacttcatc aaacacttgc tgtacctctt
    26821 gtctattttt catatagcac agcgaatcag aaaaacaggt aattgcctga tattgtccga
    26881 tttctgataa atcgagcata ttgccttcca caaattggat cgatgcgtct tcttcatatg
    26941 ctcgctggct ggcaatcatc aacatctctt ctgaaaggtc taaccctgtc actttatatc
    27001 catcttttgc aaaggcaacc gctaatgctc cagtaccgca tgccagttcc aaaatatttt
    27061 ttgtgtcttc ttgtaaatga cgtttcgaaa aagctaacca ttgctgataa agtgtttcgt
    27121 ccatcacttc atcgtaaatg aaagcaaatg tttcataagc catatgttaa tccaaccatt
    27181 cactaagatc gactagcgga gcatctgacc atagtttttc cagattatag aaatttcgtt
    27241 ctggcgcatg gaaaacatgt acgatcacat ctccaagatc gatcaatacc cattttccgc
    27301 cttcttttcc ttcaatacgt tttacttcat atttgttttc ttcttcttta tcaatgattt
    27361 cttctgtaat tgcgttgatt tgacgttcgc tatttgctga acagatcatg aaataatctg
    27421 ccaacaagga aacatttcga acgtctaaag cgataatgtc ttctgcccgt tttgaatctg
    27481 ctgcttcaat cgcaattttt aattgttctt tactatctat gatgatttcc tcctaatatg
    27541 agcagcttat ttttttgcta cccagtaatt atatgtttcg attgtttttg gataaatctg
    27601 ttgttcttgc gcaagcaaat gggccaatgt atgttttgtt tcaaatgcta cagcttcgtc
    27661 tagatcagcc catgcaatgg ctcgtgcatc ttgtacccca ggaaaatctc gacctggttc
    27721 aatatagtct gctacataaa tgattttgtc aaggagactc atcttagcag ccccagtcgt
    27781 atgcacccgg attgcatgaa gaatctctgc atcggtgatt cctaattccc gctctacaaa
    27841 cgaagcgcca acaagaccat gccagattgc attattataa ttcaataact ccggatcaaa
    27901 accgtctctt acgattacca ttttgaactc ctcatctggt cgttcttttg cataatcatg
    27961 tgtcaatgca gcaatactag ctttttcagg agaagcaccg tattttttgg caagagccac
    28021 ggctgtttct tctactccaa gcacatgctt gaagcgttgt tcgctcattc tcatctgtat
    28081 tttttgcatc aggttttctc tagaataagc agtatattca ttactatagt ccatattcat
    28141 acaacccttc attttgaata taatcaatta ctttatctgg aacaaggtag cggatagaac
    28201 agccttcttt gatcttttga cgtattttcg tggaactgat gtcgatctca ggtacatcta
    28261 cccaaattac aggatatgga gtatccgttg tgtatcctgg tcgacgtata cccacaaagt
    28321 tgaccataga agtcagctca tcgattttat accattttgg caaatattct accatatccc
    28381 caccgataat aaagtaataa tctgtatccg gattgttttg cgtcaattcc ttcatagtat
    28441 cataggtgta acttttccca ccacgagcta attcaatcgt ttcaatctgc aaaaaaggat
    28501 tgtcttccac cgctaattcc aacatgttga gtcgatgttt tgcatcaatc gtctgtttct
    28561 catcaacatg aggtggctga taagaaggca tcaaaaatac gcggtcaaga cctaaattcc
    28621 ggccagcttg ttcagccatc actaaatgtg caaggtgaac gggattgaat gttccgccca
    28681 agatccctac ttgctttttc ttctctaaga attgaggcat ttcttcagga aataattgtg
    28741 aacgaacaaa tgtcttagct tgcgtattca tcatggtcac tccttatatt gcttttactt
    28801 cttttgatag cctttgatac ttttcttttg tggaaggttt gtataataca ataacacgtc
    28861 caatgatttg gacgatttcg caatctattt ctttttctaa tacttgagct gcttcttctg
    28921 caatctcatc tgtattttga agtaacgata ctttgatcag ttctcttttt tctaaagctt
    28981 cttcaatttg aacgatcatt gctgaattga tcccaccttt tccgatttga aaaatcggct
    29041 gaagatgatg cgctttgcta cgtaaaaaac gcttttgttt tcctcttaaa ctcataattt
    29101 tccttcttcc ttaaatcaat gctttgcgtt tcaatacatc tacacccttt ggcgcccagc
    29161 ccgcaattac tactggcgct gttacagtga tccagcctag accggcaaaa acgatgtctg
    29221 ttttttcttt cacagaaaac tcaaaacgaa caagctccgg aaatgcctcg acttcatcag
    29281 gacgaggagg ctgtaataat ccacctacat gtttttgata aaattcgtct gctttttcca
    29341 gtttcgttcg atgaatattt acatcatttg acacataagc aataaatgaa gcacgattgc
    29401 cgctgataaa atcaaatctt gcaagtccgc ccaagaaaag tgtttgccct tcattcagct
    29461 gataaacttt aggtttgatt tcttttaacg gtgcaatgat ccgcaaatct tttttaccta
    29521 agtagtgcgc catttgatgg cgatggataa ttcccggtgt atcaatcaaa aaatgcccgt
    29581 catctaaagg aatctcgatt ttatccaagg tcgttcctgg aaactgcgaa gttgtgatta
    29641 catcttgtac tcccgctgta tttttgatga tttgattgat aagcgtcgat tttccgacat
    29701 ttgttactcc gacgatatag acatcccgtc catcgcggta ttcttcgatt ttttctaata
    29761 gttccgtcat ctcatgagat ttcttagcac tagttaataa tacatctact ggacgaattc
    29821 ctgcttcgta agcacgttcc ttcatccatt gtgttaattt agtttttttc aatgatttag
    29881 gtaatatatc cactttgttc ccaactaaaa gtactggatt gtcaccgaca aaacggtgta
    29941 gtcctgggat tagtgaacca ttgaagtcaa aaatatccac cacattgacg atcaatgcat
    30001 ctttttgccc taattcattc agtaagcgca aaaagtcgtc atccgtcaat gagacatctt
    30061 gggtctcatt ataatggcgt aatctgaaac aacgctgaca atagacttcc ccggaagcta
    30121 aacctttttc caaagccgtt tgcggcgtgt atcctaattc accgggtttg tttgtttgta
    30181 taacggcacc acagccgata cattgtaatt cttctgtcat tcgattccac ctcgccagcc
    30241 catatcaggg tgttttgcta atagataggc cataattctt ttttcccaaa aacgattaaa
    30301 ttgtgtcttc caactatctg ttgcgataat gggttttaca aggatgctac gtatccctgc
    30361 acgattggct ccacgtatat cagtcataat ctgatcgcct accattacta tctcatcatc
    30421 tgctaaatcc aattgtttct ttgctatgtt gatccctctt gctaaaggtt tcattgctcg
    30481 tgcaacatac aaaagatcaa atttttcaat cgctcgcgcg acacgttttg aattattgtt
    30541 tgaaacaaca acaacaggga ttcctgcatt tttcatttct aaaatccaag taagcaactc
    30601 ttctgttcca tctggattat tccatgcaat caacgtattg tctaaatcgg tcaatactgc
    30661 tttgatgcct agattcttta attgggcagg tgtaatctga tagatggctt ctaccatcca
    30721 tgttggtttg taatttgaaa acatgctgtc tcctcatctg caaaaaatga aggagcacat
    30781 aaagtactcc tcaaccccgt attatactgc atatcagcaa aaaaaactac ctctatactc
    30841 gttcgtcttt cagaaaaagc atttctttac aaaatgacca aaaataaaga ttgatcacag
    30901 aaaaatttag aaacaaaaaa caactaatat tggcggaacc tcttgtatcg tttttccagt
    30961 aatttatgct gatctaatcg aacaagttcc gtcaatcttt caatcaacgc ttttttcata
    31021 atgtgtgcga ctttatatcg tggcaactgc tcgccgttga acgtttcagg aataactcga
    31081 tcaacgattc ctaactcgcg tagttctggc gcagtaattt tcatcaactc agctgcttct
    31141 gcggcgcgac taccgtcttt ccacaaaatc gacgcaaatc cttctggaga aagcacagca
    31201 taaatcgttt cttccagcat ccagacttca tccgctaaac ctagagcaag ggcaccgcca
    31261 cttccacctt caccaatgat gatggcgatg atcggtacct ttaaatcaga catttcgagc
    31321 agatttctgg caatagcctc tccttcgccg cgctcttctg ctcctacacc gcaatatgca
    31381 cctgctgtat tgatcaaggt aatcaccggt ctattgaact tttccgcttg tttcatcagt
    31441 cgtaaagctt ttcgatagcc ttcaggatgg ggagaaccaa aatttctgcg gatattttcc
    31501 tgcagatccc gtcctttttg aataccgatc actgttaccg gtttgccatc taatcgagcg
    31561 attccaccaa caatcgcttc gtcatctgca aataaacgat caccatggca ttcctcgaaa
    31621 gaatcgaaga tctcttcaaa aaaatccaag cttgtccatc gttctttagc tcttgctaac
    31681 tgaacgacat catgtgctgt cttatccacg atctatccat cctttctgtg tatgcaattc
    31741 aagaagcgta tggattttct gtttcaattc catgcgggga acaatctgat cgacaaaacc
    31801 atgagataat aagaattcag ccttttggaa atcttctgga agttcctgct tgatcgtctg
    31861 ttcgatgacg cgtcttccag caaaaccgat caagctttgg ggttctgcta gaataatatc
    31921 gccttccatt gcaaaactgg cagttactcc tccggtcgtc gggtccgtta aaacagttag
    31981 ataaaaaaga ccttcattgc tatgccgttt gacagcagca gagatttttg ccatctgcat
    32041 tagagaaaag attccttctt gcatccgtgc gccacctgaa gctgtgaaca agacgactgg
    32101 aagactttcc tttgttgctc gttcgaataa tctggtgatc ttttctccga caatcgttcc
    32161 catacttccc atgataaaat taggatccat cactccaata atgaagggaa tcccctgaat
    32221 ggttgcttta ccagtgagga ctgcttcatg aagtcctgtt ttatcttgca tttttttaat
    32281 tttttccgta tattcgggaa atgctagcgg atctttggtt acaagatccg tatcccattc
    32341 ttcaaaactt ttttcatcaa taatcaaagc tagacgctgc catgcaccga ttcgaaaagc
    32401 gtatccgcaa tgagggcata ctttttcttc accgatgtct ttcgtataaa ggatatgttt
    32461 gcaatttgga cactttgccc acatgttatc aggaacagat ggcgagttag caggtttgct
    32521 ctctctatta ggattgatcc gaatatattt ctttttctta aacagagcca tctatgcgcc
    32581 tcctatctcc gtttctggtg tccaattcgg taaaaattct tcttgtaaaa atgctgtgct
    32641 gtaatcacct gctatgactg caggatgact aatcaaatcc atctgaaatt ctgcgttcgt
    32701 gatgattcct tctgtgataa attcacttaa ggctcgctgc atcttcatta atgcttcaaa
    32761 acgcgtattt ccatggacga ttatttttgc aatcattgaa tcataatatg gcgggatcgt
    32821 atatcccggg taaactgcac tgtctactcg cagtcccatc ccacctgctg gaagcagtaa
    32881 gttttggatc ttccctggag aaggagcaaa atggaaagca ggattttctg cattaatccg
    32941 gcattcgatt gcgtgtcctt ggaatactac ttcttcttga cacacattca aaggctcacc
    33001 ggctgctatc tccacctgtt tttttactaa atcgattcct gtgaccattt ctgttactgg
    33061 atgttccact tggattcgag tattcatttc catgaaataa aaatcgcctt cttcatccat
    33121 cagaaactcg atcgttccgg cattttcata attgactgct ttagctgctc gaacagcagc
    33181 gtctcctagt gcttctcttt ttgtttgtga gatcactaca gaaggagatt cttccagtac
    33241 tttttgattg ttgcgttgta aagaacaatc tcgctcgcct aaatgaatga catgaccaaa
    33301 tcgatcacct aagatctgaa cttctatatg gcgagcagga taaatgattt tttccaaata
    33361 catatcatca tttccaaatg ccgctgctgc ttcttgctga gctgaagaaa aatgctgtgg
    33421 gagctcttct tttgattgaa ctttccgaat gcctttcccg ccaccacctg cagctgcttt
    33481 cagcatcact ggataaccaa ttctgtctgc tatttccaat gcttcttcta ctgtagataa
    33541 tacaccagta cttcctggaa tgactgggac atttgcttct tgcatcaatt gacgcgcatt
    33601 gatcttattt cccattgcat cgatcgttgc acttttagga ccaataaatg tgatattgca
    33661 ctcttcacac atggaggcaa atcggctatt ttcagataaa aaaccaaatc ctggatgaat
    33721 tgcttcggct tttgtcacga ttgcagcgct cagtacttcc tgaacattca gatatgaatc
    33781 aacggctttt gccgggccaa tgcagattgc ttcatctgct aactgtgtat gaagtgcttc
    33841 ggcatctgct tctgaatata tcgctacggt ttggatccct agttcgcggc atgcacgaat
    33901 gatacgtaca gcgatttcac cgcggttagc tatcaatact ttagaaaaca tatttcacct
    33961 atccaatcat aaaggttaat tccgcttcgg ctactttttt accgtctact ttagcgattc
    34021 ctttgcctat tccggctgaa gttttcactt tcaatatctc aacttcaagg tataaggtat
    34081 ctcccggtgt aactttctta cggaattttg ctttgtccaa tccgccgaaa taagccgtct
    34141 ttcccttgaa ttgttcaaga gaaagtaatg caactgctcc tgcttgagcc attgcttcaa
    34201 caatcaatac ccctggcata acaggttctt ctggaaaatg tccttgaaaa aagggctcat
    34261 tgatcgttac atttttctta gcaacgatcc gttctccttc aaccatttct tccactcgat
    34321 caatcaaaag cattggataa cgatgtggaa tgatttcttt tatttcttgt atgttcattg
    34381 ttttccctct ttcctgcttt gcttattttt gctgaatcct aaagagtggc tgtccatatt
    34441 cgacaactga ctcgttttct acaaggattt ctgtgatcac tccgtcggcc tcactagtta
    34501 tctcattcat cagtttcatc gcttcaataa tgcagataac ttctcctttg gcaacttgat
    34561 cacctacttt tttgaaagct ggtttgtcgg gcgctggttg cagataaacg attcccacga
    34621 ttggcgaaac aacctcgatt ccatcaaata ctgccgattc tttttctttc attatttctg
    34681 gagcagttgt tgcttgttca ggtatgacat tgactggctc cgaaactggc aacgtttcgt
    34741 ttgtttgaac catattcatg cctcgacttg ttttattttt attcatatac aattcaaatt
    34801 gaccttcacg caaatcgaat tccgttagcg aggattgatc aaattgactg actaattctc
    34861 tgatttcatt gatatccaaa attattcctc ccagcgtttc atgcacagaa ccgcattatg
    34921 tccgccaaac cctaatgaat tactcattgc ataagtaaaa cttgcaggtt tgctttcgtt
    34981 tttgacaact gtcaagtcaa tctcaggatc ttgtttttct acattgatcg taggtgggat
    35041 aaattgatgt tctaatgcca gcaaagttgc caaggcttcg atcccgccgg ctgctcccaa
    35101 taaatgtcca gtcatcgatt tcgtgctgct gacgtaagta tctctgaaat tttcacctaa
    35161 tgcgatttgg attgcttttg cttctgcctg gtcattggct ggtgtacttg ttccgtgagc
    35221 attgatatat ccgacttgtt ccggctgtac accagcttct tccatcgcaa gcttcattgc
    35281 tttagatgca ccagaaccat ctggagtagg agctgtcata tggtaagcgt cacagtttgc
    35341 accgtatcca acgatttctc catagatttt ggcaccgcga gcttgtgcat gttctaaaga
    35401 ttcaagaact agaacgcctg ctccttcacc catcacaaaa ccattccgat tttcgtcaaa
    35461 cggaatcgaa ccacgattag gatcagttga ttctgagagt gctgttaaag ctgcaaatcc
    35521 agcaatcccc atctcacaaa tcgttgcttc tgttcctcca gcaagaatga catcagaata
    35581 gccatgtttg atgttacgga atgcttcccc aattgaattc gttccgctag cacaagctgt
    35641 tacgatagct gtacaaatac cttttgcacc tacacgcaaa gcaatatttc cagctgccat
    35701 gttggcaatc gccattggta cgaacattgg agaaactcgt tttgcacctt tttcatgtag
    35761 acgaataact tggttttcga ttgttggaag accaccgatc ccagatccga tgatgacgcc
    35821 aaaccggtct tgattcattt tttctttatc taaaccgctc atctccattg cttctaaagc
    35881 agcgtagatt ccatagatcg aaaacatatc cattcgtttg ctatcttttt taataaaata
    35941 tttatcgtaa gggaaatctt tgacttcacc cgctaaggta atccctgttt ctgaagcatc
    36001 aaatttagtg atcggtgcga tgccattcgt cccctctttt aagctattca aaaagctgtc
    36061 tgcgtcattt ccaataggtg aagtgactcc atagccagta attaccactc gattcatttg
    36121 tttgctctcc ttttcttatc cgtgcatgac caatccgcca tcgacattga tgacttgtcc
    36181 ggtgatatat ggattttgtg ctaagaaaac tgctgtttgt gcaatatctt ctacttgtcc
    36241 gaaacgctgc atcggaattt gcttttccgc ttgttccttg actttgtctg ctaaaacttc
    36301 cgtcatatca gttgtgatga atcctggcgc aatggcatta catgtaatgc ctctagttgc
    36361 agcttctcgt gccacagatt ttgttaatcc tactacgcca gctttactag ctgcataatt
    36421 tgcttgacca atatttccaa tcaacccaga tacactagag agattaatga tggccccttc
    36481 tcgctgcttc atcatttttt tcaatacgtg ctgcgtcata ttgaaggttc caatcaaatt
    36541 gatatccaga cattttttga aatcttctgc atccattcgc atcacaagtt tgtcatttgt
    36601 gattccggca ttgtttacta acacatggat cgatccaagc ttttcttctg cttctttgat
    36661 catttgtccc gctttctcat aatcagagat gtcaccggaa actcctacgc attttacacc
    36721 gaatgcttcg atttcttcta tcttttcttt tggaatctct ccgcgaccat tcaaaatgat
    36781 atttgctcca gcttttgcaa aagctaaggc catcgctttg ccgattcctc ttgtactacc
    36841 tgtgataaat acattttttc cttttacatc cataacgttc ctccttatag tattgctatt
    36901 gtttcatcaa atgtctgctt attctcaaca cgcagaactg gtattgtttt atcgattttt
    36961 ttcataaatc cgcttaatac ttttccgggg ccgacttcga tgacttgttc gatgccgatt
    37021 gtttttaact tatggatact ctcatagaaa cgaacaggtt gcatgacttg ctgttcaagt
    37081 agtcccgcga ttgtttcttt cttcattatt tccgttgttg tgttgcttat gataggaaaa
    37141 gaaggttcag agaattgaat ctgacttagg tccttcgcca gtttttttgc tgccggttct
    37201 aaaatagctg tatgaaaagg cccgctgaca tttagaggga tcattctttt gaaccctttt
    37261 tcttttaata gtaaaacagc ttcgtctact gctttttctt cgccaccaat cacgatctgc
    37321 tgaggtgtat tataatttgc aggagatacg atgccgtact tgctagcttc atgacagctt
    37381 tcctcgatcg tttcaatcgg cgcattcatc actgcaacca ttttcccgct tccagctggg
    37441 gcagcttctg tcatataagc gcctcttttt gctactaacg caactgcttc agtgaaggat
    37501 agcgcattac tagctactaa tgccgaatat tctcctaaac tcagtcctaa agctgcatct
    37561 gggatgattc catgctcctt caataagcga taatacgcga tgctgactgt tagaatagct
    37621 ggctgtgtat attgcgtctg atccaaacgt tcattttctg taaagcaaag ttcagccata
    37681 tcgtagccga gaatctcact tgcttcatca aatgtctgct ttacaacggc ttcttcatat
    37741 aaatcttttc ccataccttg atattgtgca ccttggccac taaataagaa tgctgttttc
    37801 atgtttttct ccaatatatc cagaatatat gtttgattct tcctattcaa aaaggccgag
    37861 acattcctat ttcaggaaat gtcccagccc ccaacctaat tttaatgatt atgcagtttg
    37921 tttttctacg taagtcacta aatcttgaac cgttttgatt ccgtcttctg tttcgatttt
    37981 cacgtcaaat tcatcttcaa tttcattgat gatttggaat aaatccaagc tgtcagcttc
    38041 taagtcttct tggatgtcag tagtcaattt gatttcttca gtttcttttc ctaattcttc
    38101 tgcgatgatt tcttgaattt tttcgaatac cataataata tattcctccg atattgtttg
    38161 ctttttattt ttataattta acagtctaca actccatgag aatacttccc catgttaaac
    38221 ctccgccata gcctgtaaat attactttct gctgttttcc taaggtgatc tttccactag
    38281 aaactgcttc atccaataag atagggatgc ttgcagcaga tgtattccca tatttatcca
    38341 tattggtcag gaacttttct tgcggcatct ttacttttcg ggcaattttc tcaataattc
    38401 tgaggtttgc ctgatgcaaa agcagataat caactggttt gtctttcatg acttcttgga
    38461 tattgtttgc aacgtctcgt acggcaaaat caaaaatatc tctgccagtc atttgcaaat
    38521 aatacgaacc ttctgaatct tctgaataga acggattttt attttgctgg tagccagcgg
    38581 tcaatgagct acttctggta ccgtcagctg ctaatttttc tttcagcaat tttttctgtg
    38641 gattcgcttc taagagaatc ccacctgctc catcgccaaa caacacagca gtcgtacgat
    38701 cagaccaatc gattagctta gatagtgttt caccaccaat caccagtccc ttagttgagc
    38761 cgcagcggat cattttttca gccatgctta acgcataaac aaatcctgag cacgcagcac
    38821 tgatatcaaa agcgatagca tgagttgctc ccaatttccc ttgtacttgt gctgctacag
    38881 atggtgtcgt gtaatcgggc gacattgttg ctactaaaat aaaatccaaa tctttagggt
    38941 ttagattttt ctgttttatc aatttttccg ccactaaaat gcataaatca gaagtctcct
    39001 gatttgttac acatcttcgt tcacgaatac ccgtccttga cgaaatccat tcatcagagg
    39061 tatccatcat cttggaaaga tcattattag taataatctt ttcaggaagg acgctggctg
    39121 ttgcagtaat cattccaaat tgttccatta aatatcctca cttatagtct tgcaagaagt
    39181 cgtgcaagtt tttcagtgca tccagcaagg catgctgttc ctccgtagcc attccgtcta
    39241 agatgttctt gaccatttca cgatgaaaat gctgatggac ccgaaatagt aactttcctt
    39301 ttttcgttag tcccaacttt acaacgcggc ggtcatcttc actgcggata cgttcgacat
    39361 agcctttttt tactaacttg ttaatagcag tggtcaaggt cccaacagta attgatagtt
    39421 ctttggctac ttctgaagtt gtttttttct tgtacatccc gattgcctcg atcgtgtgca
    39481 tctctgtgat tgacagatct ttgaattgag attttttcag ctcagactct tcgattgtca
    39541 aaatatcatt gaagacacta acaagataat catttactgt ttttaaatct ggttccatgt
    39601 tccaccgtcc actaattagt ttgattatca aatcttttga tgttcaaact atatcttaac
    39661 ttttttcaaa atgcaacctt aaaagatcat ttttttacta tatgagcttt ttttaagatt
    39721 ttactcattt aaaacaactg ataaatcagc atttataatt tcttttatta gaaaaatcat
    39781 ctatctcaca tattttgatt atcaaagtat tttctgtgaa cagaactata gaattcccta
    39841 aaacttgtcc attatttcaa aatttgttat agtcttttta ttcaaagcgt aaaaggagat
    39901 cctatgttaa aagaaaaaat gaaaactctc cccatgctgc cgggtgtcta tcttatgaaa
    39961 gaccgagatg gtaaggtcat ctatgttggt aaagcaaaac ggctcaaaaa tagagtaagc
    40021 agctattttc atcagaataa acagcattca aaaaaagtat tacgtatgat tcatcatata
    40081 acagattttg atttcgtcgt agtagacacg gaattagatg ctttattgct cgagtgtcaa
    40141 ttgatccaac attaccgtcc tttttataac cgacaaatga attatttcag taattataat
    40201 tatgtacata ttaccaataa gggatttgta ttaacagata ctcctacggc tcgaacatac
    40261 gggccttttc gtctctataa aaaaatgccg tctattttgc gtataatgga agaaacttat
    40321 caaatgcctt ggttgtctga aattagtttg ttagctttgc gagtccagct tcctgaccta
    40381 caggaaatga cttttgaaca gaaaaaaaag gaactccaag ggctgtttca aggccgaaat
    40441 aaaaagctac tgacttactt gaaaaaaaga caacaacatt tcatctatca gttgaatttc
    40501 gaaaaagccg gtatgcttca aaaagatatc gaattagtta cttattttat tagacggatc
    40561 caggaacaaa agcagttttt aagaacacca tcgctcacct tcagcatgcc attagcagca
    40621 gatgagagtc agaaaaagca ctacctcgtt tgttatggtc aacttgcaga aacaatgatt
    40681 acctctggtg acgtttctcc tgacttctat tatgaaaaga aagaagctca tttatctttg
    40741 aaacgtcaat tgtcaaaaga agaaatcgat cctgtacaaa tcttgatcag ttaccgcaaa
    40801 aaattagaaa aagaacagtt tgaaattgaa ctgttaaaca aaaaagaagc tgaaaagcaa
    40861 ctaaattagt tgcttctcgg cttcttttag gcatcttcaa cttcaaatgt caattatcct
    40921 aaaatttatt ggattaagtc atagatttcc atcgctacga tatcgatatt atcaaattcg
    40981 tattgctgat gagtatctgt ttcagttaat tcaaatgtat cggtcgcttt atcataagtt
    41041 actgtacact tctctacgcc ttctttttca aaacggcgaa cttgcagttc attatctgct
    41101 gactcgacca tagcctccag tcgttttatg attgcgacta attgtgaatg tgtcatcgga
    41161 ggtcctcctt ttcttatttc tgttatattg tatcaaaagc atagcctact tgcattgatt
    41221 ttctctaaaa aaactcgttt tttatgattt tttttctggt atttttcctt caggccacca
    41281 aagtttgatc aaagcttggg ttccgtcatt ctcaaaacct ttatctgcca actcttcata
    41341 tagtttcaat gcttgggtag ttgctggcaa tacaagatcc attttttctg cttcttctaa
    41401 tgcaatcttt aaatctttga taaaatgttt gacaaaaaaa ccaggtgtgt aatcttcttt
    41461 taaaatacga ggagaataat tgcttaaaga ccagttagct gcacttccac ctgaaagcgt
    41521 ctcaatcact ttctttaaat caagtccgtt tttttgtgca tagacaagca tttccgtcat
    41581 tcctgtcatc gtacctgcaa tcatgatctg attagccatt tttgtatgct gacctttccc
    41641 agcagaacca tgcaatgtaa atgtcgtacc aaattctttg aataaaggca gtacttgatc
    41701 ataaacggct tcttctccac cgaccatgat cgtcagtgta ccattctttg ctcctaagtc
    41761 accaccggat accggtgcat ctaacgcatc tgcgcctttt tcttttgctg tttttgcaat
    41821 tttttctgcc aggcttggtg tacttgtagt caaatcaact aaaatatgtc ctgagatatc
    41881 tgcagaaaaa atccccgact gtccatagta gatttcttct acatctttgg ggtaacctac
    41941 cattgtaaag agaatattac tttgttctgc taccgctttt ggtgtatctg cccagatagc
    42001 tccttctgtt actaaaggat cagcttttgc ttttgtccga ttatagacag ctacttcgtg
    42061 tcctgcttct agtagatggc gtgcgacagc acttcccatg acgcctgttc cgataaaacc
    42121 aagtttcatt ttttcgacct cctaaaaatc aaaaatcctt gcttctatgc tagtatacgc
    42181 tagaaacaag gattttttca taaaaaatgt ttgaatttta tcttttaaat gaatttaatt
    42241 ttattttgat tcgttcaatc gagtcttctt cttcttttct tcgcatctct tcttcatgat
    42301 aaacaaccat gtcttgataa aattcgatca tagcttcgcc gaaatgtgta gatgaaatat
    42361 cataaagttt agcttctaaa acttttggat ctttaggaac ttcactggaa atataatcaa
    42421 taagtgctgg tgcaaagtct tcgtcggttt caaaagtttt ccctaatgaa ggatgatcga
    42481 acaatcggtt caaataagca tttccttcca cgacacaagg tgttccggct gccatcgctt
    42541 ctgtataagt aagcccttgt gtttctgaag tagaagcact gacaaaataa tctgccgctt
    42601 tataataaag tgctacatca ttgttgtcca cttctcctgt gaactgcaca aattcttcta
    42661 actgcagttc tgagatcaat tcctctaact cttctacata aggtcctttt cctacgataa
    42721 ctaatctggc gttaggataa gcggagatga cctgaggaaa cccattaatc aaggcttgga
    42781 tatttttctc ataagaaatc ctgcttaaag aaagaatcat caaatggttt tcctgaagac
    42841 ctagtgactc ccttaatttg ctgatatcct gctgagtgat atcagaacgt ttgaattttt
    42901 caatgtcgat accagtagga atcacgcgaa gcggtgctat tacaccatag ctgcgtaatg
    42961 tatcaataac acgttcactt ggacaaacta cacctgtcgt atgatttgca aataatctag
    43021 acaagtattt tacatgggat tgcctgatca cttttccttt accgatataa tgaaggtagt
    43081 cttcatacat cgtatggtaa gtatggatca gaggtatttt caacttctta gctaccatct
    43141 tcccaagtat ccctgctccg aattctgtat gggtatgaat aagatctagt tctagttctt
    43201 tggcaaccaa ataagcatac cacatgcctc taacaacaac tcttcgatcc ttgaaagaaa
    43261 taaatggtac acttggcatt cgaatcacat ctttttccaa cttatccgca ttaggatcgg
    43321 tcgttgtaaa aatatagact tcatgcccat gtctttctaa ttcttgtttt aatgttttga
    43381 tcgatgtagc aactccgctg acttgcggaa agtaggtatc ggtaaaaaag ccgattttca
    43441 tgtttttcgc ctccaaacta gtccttgacc tgatttactt tttttaattt gctagagact
    43501 ttttcattca gtacactttc gtatacattt ttaagttctt caccgatttt attgatactt
    43561 cgctcttttg ctgtttgata accggcttgt gtcgtactcg gtagttcttg attggtaatc
    43621 tgttggatca gtcggataaa ttcttcgttt gtcttcccca tatagcagtt cttgctatct
    43681 tctaaccagc cattatacac tggaatatct cgaacaagta cgttttgttt gcttgctaaa
    43741 gcttctaaaa caacgatccc ttctgtctct tcataagaag ggaaaaagaa tagatctgca
    43801 cctgaatacg caccttctat gatctctcca cgaatgtaac caggaaacag gacattttca
    43861 ggatgatctt cttttacaat tttccggatg ttccgaggaa tcgagtacat gggaacatga
    43921 ccaaaccaaa taaatgtgta ttcgggcatc ttcttagcaa tttctacgaa atcaatgatt
    43981 cctttacgtt cgaaaaacaa accgacacaa atgattactt tttgatccgg agacagtttg
    44041 aaatattctc tgaacttttg ttctttcatt ggatcagggt gatatttctc taagtcgatc
    44101 ccattggaaa tagcttgaat cggcacacgg ataccatagc tttccaacaa ctgttttgaa
    44161 taaggtgttg gcgtgatcag atagtccgct ttttggtaca atcctaccag atattttttt
    44221 acgataggag aaagctggtt cgatccgata aaggaatttc ggaaatcttc ctctgtagaa
    44281 tgcgcatgat agacaacttt ttttccttct cttctggctt tattgaccat attatgacta
    44341 ttgattccgt atgtattgat gtgcaggatg tcataatctt ctttttcatc tagtgtataa
    44401 gagataccga cttccgtcag agcacgtttt tgatgatcaa gcgcacgccc gattccagat
    44461 tttgcaagca tcttttcact ttcaaaatat aataatacct tcaccttacg tcccccttca
    44521 cttatatagt ataacatagc ctacaaactg tcactcaaac ttaagcccta tttttgtcta
    44581 ttcttactga caaaaacgtt ttcttaaaaa agaacaaaaa aactggcgta gctcttttac
    44641 aagccacacc agcttttgat acgttgttta ttttacatat tcatgaacaa gttcaacgac
    44701 ttcttccatc gtatcgcatt ctttcaatgc acgatcagca agttcagcca ttttcgctgt
    44761 gtccaagcgt ttcattaaac tacgcgtttt aagaatagat gtcgcactca ttgagaactc
    44821 atctagaccc atacctacta gcaatggaac agctgtttga tctccagcca tttctccaca
    44881 catacctgcc cattttcctt cagcgtgtgc tgcatcaatt acatttttga tcaaacgtaa
    44941 aattgatggg ttatatggtt ggtacaagta agaaacgcgt tcgttcatac ggtctgctgc
    45001 cattgtgtat tgaatcaaat cgttcgtacc tacagagaag aaatctactt cttttgcaaa
    45061 cttgtctgct aagactgctg ctgctggaat ctcgatcatg atgccgactt ggatcgtatc
    45121 agatacttcc ttgccttcac ttatcaattt ttgtttttct tcttcaaaga tcgcttttgc
    45181 tgcgcggaat tctttgagtg tagctaccat agggaacatg atacgtaaat taccatgaac
    45241 agatgcacga agcaatgcac gcatttgtgt acggaacatt tcgtcgcctt gttcagataa
    45301 actgatacgc aatgcacgat atcctaagaa tggattcatt tcatgaggta attgcagata
    45361 tggtagttct ttatctccac cgatgtccat tgtacgaaca actacaggtt ttccttccat
    45421 accttctaat acagctttgt aagcttcata ttggtcatct tctgttggga agtctggaga
    45481 atccatatac aggaattcag tacggtacag accaactgct tctccaccat tattatggac
    45541 accaactaga tcttttggtg ttccgatgtt tgcagctaat tcaaaatgct tgccgtcagc
    45601 tgtgacagtt tctgcatttt ttaatttttc ccattctgct ttttgtgctg cgtaatctgc
    45661 acctgctttt tcaaattcag ctttttgttc atctgtagga tcgatgatta catcgccttc
    45721 gatcccgttg acagccaaaa tatcgccttc tttgacttta gcagtaattt cttttgtccc
    45781 aacgattgct ggaatttcta aagaacgtgc catgatagca gaatgtgaag tacgtccacc
    45841 aatgtctgtt acaaacgctt ttacaaaatt gcgatctaat tgtgctgtat cacttggagt
    45901 caagtcatgt gcaacaacga ccacttcttc gttgatcatt gatggatttg gtaaagtaac
    45961 gcctaataag tgcgctaaaa tacgtttagc aacgtcacga atatctgcag cacgctcttg
    46021 catataagca ttatcttcca ttgcttcgaa catatcgata tacatatccg ttacttcttt
    46081 tagcgctgat tcagcattta cgctgttgtc tttaatattt tgcttgattt gacctaccat
    46141 ttctggatct gaaagaacca tcaaatgggc atcaaatact tgcgcttctg cttcacctaa
    46201 gctttgcgct gctttttcac gaatttgctg caattcttca gtagatttag ctaatgcagc
    46261 atccaaacga gcttcttcag ccgcagtatc ttctactgtt gccttactga atgttaaatc
    46321 cggttgaact agcaggtaag cttttgcaac ggctacaccg tcactagcgg caatcccttt
    46381 tagcatttca accattattc agataagcct tctttcttca ttgtttcaac gattgctgcc
    46441 attgcatcag cttcgtcagc accttctgca gtaatagtaa catcagaacc ttgacctaca
    46501 cctaaagaca taacgcccat gattgatttc aagtttactg atttaccttt atactctaag
    46561 tttacatcag agttaaattt gcttgctgtt tgtactaata gtgtagctgg acgagcgtgg
    46621 atcccagttt ctgctactac gtgaaattct ttcttttcca tattaatcgg tctcctttaa
    46681 gtgagtgttg tttttatgtg agggttttct tttttagtaa ttcagagaat cctaacaaat
    46741 gccacccttt catctgtaaa gattaacatt ttttttcgtt agatacaaca gttttcattc
    46801 aatttcagat aaaagtattc aaattattcc ggattctttt tcatcctttt cttcacattt
    46861 tataacaaac gtgtttattt cctttttctt gtcgctttct cttctcctga cgtttatcat
    46921 tctttccttt gaccctcttt gttttcatat gaaacgaatt acttgcttcc ctttttattt
    46981 ttagtataat aagagtcaaa ggtcaggaat ggtcaataga gatttcacct tttctacctc
    47041 ataaatctct taaaaaacta ggggttattc ttttacctca tgaaaaacga gatgtaaaat
    47101 atggatgtac ccatttttgt gaaaggacgt gaatgattca tgctttgtca aaactgcggc
    47161 aagaatgagg caacgattca cttgtatgcc actgtcaatg gtcagcggac acaactcgat
    47221 tactgtcaga gctgttatca aaaaatcaaa aatcaacaaa atggaggtct gactaatatg
    47281 gcccaaaatg atccatttgg atttggcagt ttggacgatc ttttccgttc catgtctcgc
    47341 caaatgcaac agcaaggaaa ttatgagcaa acaccaccaa cacaatttgg cggaaacaac
    47401 aacttcaatg gtggtcagcc acctcaaggc aatacagaag gtttattggg agaatacgga
    47461 atcaatatca cagaacaagc acgacaaggt gatatcgatc ctgtgatcgg acgcgatgac
    47521 gaaatcaaac gagtcattga aattttaaat cgccgaacca agaacaatcc tgtcttgatt
    47581 ggagaaccag gtgttggtaa aacagcagtt gttgaaggtt tagcacaaaa aatcgtagat
    47641 ggtgatgtac cgcaaaaatt aatggacaaa gaagtcattc gtttagatgt cgtatcttta
    47701 gtccaaggta ctggtatacg aggacaattt gaagaacgta tgcaaaaatt gattgaagag
    47761 atccgtcaag cagaaaatgt gatcctattc atagatgaag ttcacgaaat agtcggtgct
    47821 ggttctgctg gtgatggaaa tatggatgct ggtaatattt taaaaccagc tttagctcga
    47881 ggagaattgc aaatggttgg tgctactacc ttaaatgagt accgcatcat cgaaaaagac
    47941 gctgctttag aacgtcgtat gcaacctgta cgggtagatg aaccaactgt cgaagaaacg
    48001 atcagtattt tgaaaggttt gcaaaaacgt tatgaagact atcatcatgt aaaatatact
    48061 gatgaggcca tcgaagcagc cgcaacttta tccaatcgtt acgtccaaga tcgcttcttg
    48121 ccggataaag ccatcgattt gctagatgaa acaggttcta agaaaaactt gacgatccaa
    48181 atcgttgatc ctaaaacaat cgagaaaaaa ctgcaagaag cagaagaaca aaaagtttta
    48241 gcttctcgag aagaagattt cgaaaaagca gcttattatc gcgatcagat caataaactt
    48301 caaaaaatga aagaacgtca gctcactgaa gaggaaacac ctgtgattac cgaaaaagat
    48361 atggaaaaaa tcgttgaaca acggacaggt attccagtgg gtgaattaaa agaaaaagaa
    48421 cagacacaac tgaaaaactt agcagatgac ttgaaagctc atgtcatcgg acaagataac
    48481 gctgtagatc gagtagcgaa agcgattcgc cgaaaccgtg ttggattaaa caaacagaat
    48541 cgtccaatcg gctccttctt atttgttgga ccaactggtg taggtaaaac agagcttgcg
    48601 aaacaacttg cctacgaact attcggttca caagattcaa tgattcgttt cgatatgtct
    48661 gaatatatgg aaaaacatag tgtctctaaa ttgattggtt ctcctccagg ttatgtcgga
    48721 tacgaagaag ctggtcaatt aacagaaaaa gtacggagaa atccttacag tcttgtcttg
    48781 ttagatgaag tagaaaaagc tcatccagat gttttgcata tgttcttgca aatcttagat
    48841 gatggtcgat tgacagatgc acaaggaaga acggtcagct ttaaagatac gatcatcatt
    48901 atgacaagta atgccggaac tggtaaagta gaagcaaacg ttggttttgg tgcggcacgc
    48961 gaaggtgtta ctcgttctgt attgaaccaa ttaaacaact actttacacc agaatttctg
    49021 aaccgttttg acgggatcat cgaattcagt gcattatcaa aagaaaactt gatgacaatc
    49081 gtcacactaa tgctagacga tgtcaaccaa atgctggcag cacagcaact tcacatcgaa
    49141 gttcctacga atgtcaaaga aaaattagtt gacttaggct atgatccatc tatgggtgct
    49201 cgtcctcttc gacgcacgat ccaagaacaa atcgaagatg gtatcgctga attttatctt
    49261 gatcaccctt ctatccatga gttgaaagca aaactggata aagatggaaa aatcatcgtt
    49321 acttctaaac cagaacgttt ggctaaagaa tcagccgaag aaacggctga ataaatccag
    49381 ttttatagcg tgagacggta tttctttgag aaatgccgtc tcattctttt ttcagaaaag
    49441 tcaaaatact gttcatttta taaaaaagaa attataataa gagaaacaag caattaaaaa
    49501 tacataaaag aggtgagcgc catgaaattg gtaaatgtaa caaacagcca ttcccgtctt
    49561 gtattaaacc agcttgaaaa cactgatgcc catctagtca aggtctacac agccggaaat
    49621 accactattg tctacactga agcccctgaa cataatgaaa ttctgctgat caatgacaaa
    49681 cgtaaaatcc agccgaaaga aatcgaagat gctaaaaatt atttcttaga taaaatcaaa
    49741 gacgccgttt accacgagga tgaaatcaaa gtaatcgaat tggcaggcct tgttgaaatc
    49801 tcgattccaa aacatgaatt aggcgctaca ttagccgtgt aaacaaattt tgaacataat
    49861 aattaaagag cgtgggacaa aagtaaa
//
LOCUS       DAFEKH010000020        47854 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.021, whole genome shotgun sequence.
ACCESSION   DAFEKH010000020
VERSION     DAFEKH010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 47854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47854
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.021"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(38..1189)
                     /locus_tag="LP386_001218"
     CDS             complement(38..1189)
                     /locus_tag="LP386_001218"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBL1918466.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(1202..1639)
                     /locus_tag="LP386_001219"
     CDS             complement(1202..1639)
                     /locus_tag="LP386_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL1918467.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            complement(1654..3420)
                     /locus_tag="LP386_001220"
     CDS             complement(1654..3420)
                     /locus_tag="LP386_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HBL1918468.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEALATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            3684..4361
                     /locus_tag="LP386_001221"
     CDS             3684..4361
                     /locus_tag="LP386_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1918469.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            4364..5491
                     /locus_tag="LP386_001222"
     CDS             4364..5491
                     /locus_tag="LP386_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1918470.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLPLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(5691..6131)
                     /locus_tag="LP386_001223"
     CDS             complement(5691..6131)
                     /locus_tag="LP386_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL1918471.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAKTIEEVQMIFEHGHI"
     gene            complement(6142..8175)
                     /locus_tag="LP386_001224"
     CDS             complement(6142..8175)
                     /locus_tag="LP386_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBL1918472.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            complement(8177..9880)
                     /locus_tag="LP386_001225"
     CDS             complement(8177..9880)
                     /locus_tag="LP386_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL1918473.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKKSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            complement(9974..10924)
                     /gene="manA"
                     /locus_tag="LP386_001226"
     CDS             complement(9974..10924)
                     /gene="manA"
                     /locus_tag="LP386_001226"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HBL1918474.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIATEPGK"
     gene            complement(10963..11988)
                     /locus_tag="LP386_001227"
     CDS             complement(10963..11988)
                     /locus_tag="LP386_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBL1918475.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            complement(12197..13066)
                     /locus_tag="LP386_001228"
     CDS             complement(12197..13066)
                     /locus_tag="LP386_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HBL1918476.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            complement(13525..15417)
                     /locus_tag="LP386_001229"
     CDS             complement(13525..15417)
                     /locus_tag="LP386_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1918477.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(15414..17141)
                     /locus_tag="LP386_001230"
     CDS             complement(15414..17141)
                     /locus_tag="LP386_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1918478.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(17157..17807)
                     /locus_tag="LP386_001231"
     CDS             complement(17157..17807)
                     /locus_tag="LP386_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBL1918479.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            18011..18307
                     /locus_tag="LP386_001232"
                     /pseudo
     CDS             18011..18307
                     /locus_tag="LP386_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            18479..19099
                     /locus_tag="LP386_001233"
     CDS             18479..19099
                     /locus_tag="LP386_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HBL1918480.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(19191..20357)
                     /locus_tag="LP386_001234"
     CDS             complement(19191..20357)
                     /locus_tag="LP386_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL1918481.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(20369..20722)
                     /locus_tag="LP386_001235"
     CDS             complement(20369..20722)
                     /locus_tag="LP386_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBL1918482.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLETVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            20850..21872
                     /locus_tag="LP386_001236"
     CDS             20850..21872
                     /locus_tag="LP386_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HBL1918483.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            21891..22052
                     /locus_tag="LP386_001237"
     CDS             21891..22052
                     /locus_tag="LP386_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918484.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(22311..22745)
                     /locus_tag="LP386_001238"
     CDS             complement(22311..22745)
                     /locus_tag="LP386_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918485.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLKKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(22855..24714)
                     /locus_tag="LP386_001239"
     CDS             complement(22855..24714)
                     /locus_tag="LP386_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBL1918486.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(24832..25992)
                     /locus_tag="LP386_001240"
     CDS             complement(24832..25992)
                     /locus_tag="LP386_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HBL1918487.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(26299..27723)
                     /gene="araA"
                     /locus_tag="LP386_001241"
     CDS             complement(26299..27723)
                     /gene="araA"
                     /locus_tag="LP386_001241"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HBL1918488.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(27739..28437)
                     /locus_tag="LP386_001242"
     CDS             complement(27739..28437)
                     /locus_tag="LP386_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBL1918489.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(28394..30055)
                     /locus_tag="LP386_001243"
     CDS             complement(28394..30055)
                     /locus_tag="LP386_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HBL1918490.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKR
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            30273..31673
                     /locus_tag="LP386_001244"
     CDS             30273..31673
                     /locus_tag="LP386_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HBL1918491.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKVLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIIGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(31925..33004)
                     /locus_tag="LP386_001245"
     CDS             complement(31925..33004)
                     /locus_tag="LP386_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL1918492.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(33090..34049)
                     /locus_tag="LP386_001246"
     CDS             complement(33090..34049)
                     /locus_tag="LP386_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBL1918493.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(34061..35572)
                     /locus_tag="LP386_001247"
     CDS             complement(34061..35572)
                     /locus_tag="LP386_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBL1918494.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(35594..36157)
                     /locus_tag="LP386_001248"
     CDS             complement(35594..36157)
                     /locus_tag="LP386_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBL1918495.1"
                     /translation="MKIVETKFYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(36163..37026)
                     /locus_tag="LP386_001249"
     CDS             complement(36163..37026)
                     /locus_tag="LP386_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL1918496.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(37040..37936)
                     /locus_tag="LP386_001250"
     CDS             complement(37040..37936)
                     /locus_tag="LP386_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1918497.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(38111..39400)
                     /locus_tag="LP386_001251"
     CDS             complement(38111..39400)
                     /locus_tag="LP386_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL1918498.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(39372..40889)
                     /locus_tag="LP386_001252"
     CDS             complement(39372..40889)
                     /locus_tag="LP386_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBL1918499.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            41087..41977
                     /locus_tag="LP386_001253"
     CDS             41087..41977
                     /locus_tag="LP386_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HBL1918500.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(42050..42874)
                     /gene="nadE"
                     /locus_tag="LP386_001254"
     CDS             complement(42050..42874)
                     /gene="nadE"
                     /locus_tag="LP386_001254"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HBL1918501.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(42886..44358)
                     /locus_tag="LP386_001255"
     CDS             complement(42886..44358)
                     /locus_tag="LP386_001255"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HBL1918502.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(44995..45357)
                     /locus_tag="LP386_001256"
     CDS             complement(44995..45357)
                     /locus_tag="LP386_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBL1918503.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            45580..46332
                     /locus_tag="LP386_001257"
     CDS             45580..46332
                     /locus_tag="LP386_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBL1918504.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(46472..47395)
                     /locus_tag="LP386_001258"
     CDS             complement(46472..47395)
                     /locus_tag="LP386_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1918505.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(47410..47682)
                     /locus_tag="LP386_001259"
     CDS             complement(47410..47682)
                     /locus_tag="LP386_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918506.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        13932 a         9944 c         8258 g        15720 t
ORIGIN      
        1 aaaaatttcg tcacattccc ctttttcgta tcctatttta agcgacttgc ttggcataac
       61 ggttcacgtt ttgcttgata ttcccgattg ttttcggatc attgattcct gtgacttctt
      121 gaatcaattg ttccaagttt tcatggatct tcatttcatg caattgacgg ctttgttcat
      181 cttcaggatc atagtaatta aaaataatcc ccattgttgc cgtcaaatgt gggcaagtca
      241 agttatgttc ttgtagttct ctcactggac gtgtaaatct ttcttgataa cctaacttac
      301 gtaatggtgt ccgagcgaca cgtgtgatcg catcagagat atttttgttt tggaagcgat
      361 gaatgatttt ttcaatatac gcatgatgct gctctgcatc aaacccccat ttggcaatca
      421 gcaaacttcc tgtttcctgc aaaactgatt ttaattgtgc cacaactaac gcatcttgca
      481 ttgcttcatc aatggtctgg taacctaaca aggcacctgt ataagcgaca gtcgcatgac
      541 cagtattgac actaaatagt ttgcgttcga tatatggttc tagatcatct acatataaaa
      601 ccccttttaa ttggattttt ttattttttc tttggctatc gtcaatgacc cattctttga
      661 aaggttccac ttggacgaat aaaggatctt catggtgttg taatgggacg attcgatcga
      721 ctgctgcatt tggaaagccg atatatttgt cagtaaatga tgtttccgga agatatttat
      781 acacttcttt ttctagaaat gctgaaccgc caatcatatt ttcacaggca atgatatcta
      841 aagatgttgt gcttccttcc ttttctcttt cttggatacc ttttgcaatc aactcagcaa
      901 taaaaggtaa gatattcggg ccaatggcgg tagtaactaa atctgcttca gcgatttctt
      961 ggattacttt ttctggattt gtttgattgt tgattccttt gacatttttt acagtgattt
     1021 tttcttttga ttcatctgct aattcgattt cgtattcttt tctttcattt aaagcatcaa
     1081 tgatcgtgtg attcacatct acgaaagtaa tctcaaatcc attagctgcc aaaacctctc
     1141 caataaatcc tcgaccgata tttcctgcac caaaatgtac tgctctcatt tttctctctc
     1201 cttaagcaat tgctagattt tccgttactt cttctttgct gagcgcgtct gctagctgga
     1261 caacattgtc catatcactg caataaagtg cgatttgctg tacaagttgc aaatgctcat
     1321 ctccgactcc tgcaataccg aacaaaacag tcgcaatctt ttcttcttct tcggtaccaa
     1381 aatctacacc atctggtact tgaacgacac agatgccgga ttttttcaca tatttttttg
     1441 cttcatctgt tccatgagga atcgcgataa aattccccat ataaacagat aacattttgt
     1501 ctctatctac catggcatcg atatattcct catcaacgca ccctgcttct acaagcatct
     1561 gaccgcaata gcggatcgct tcttctttgg ttttaaaaga tcgattgagc tcgatcatgt
     1621 cgaatggcaa actttgcatg ctgttttcct cccttaagct gtctgtttca aatattgtgc
     1681 aatcgattcg tatttttgcg gattgaccat gctgttgact gataaatgaa tggattgagg
     1741 tgcagccatc tgtacttttt ccgctaaact ttctttggct acgatcagtg aatcaggttc
     1801 atcttttaaa tcttggatat tgacttttct taacgggata gttaaatggt tcttgtctaa
     1861 tatatctttg agcacggtca tccccattgt tgctgatccg gaacgatcat cgtggacaag
     1921 tagaatctct ttgatttgtt tgatgtttgc tgaaagaaac tcttctgctg gctcattctc
     1981 aatttcagaa actgatgttt tctgcttgct gcttaattct tgaatgattt catcatatcg
     2041 aggtgaattc aaaaagtttt ctactgagac aaaacgcgcg ctcggtgctt tttgttttgc
     2101 tctttcttgt agttcgacct gagtaacgat caatgtattc gagtcatctg tcagttggct
     2161 gattgcttga ttggtcaccg tttgaggcaa gtctgcttcc tgtacttttt ttctcaagat
     2221 cgaagcgccc atcgcacttg atcccattcc tgcatcacaa gcaaaaatga ttttttgtac
     2281 gccagagaat gtagctcctt gaggaatacc ttgggcacct ttggaagctt gcttagctgc
     2341 ctttgtctct tgaacagatt tttcgaagtc ttcatttgta tctttcgcat ccgctttcaa
     2401 aattactgca gaaataccaa acgaaacagc tgcggcaaca atcacgccca aaataacagg
     2461 aaggtaagaa ttgaacggtg tcatcgctag aatcgcaatg atcgaccctg gagaagctgg
     2521 cgctcttagt ccagcatcca tcaattggaa aatgaaactt cctgacattc ctccgcctat
     2581 aactgataag aataataacg gtttcatcat aacgtaagga aaatagattt catggatccc
     2641 gcctaaaaag tgaatgatca tggctcctgg tgctgaagat tttgctgctc ctttgccaaa
     2701 caaagtaaaa gcaagtaata cgccaagtcc tggaccagga tttgcttcaa gcaagaatag
     2761 aatagatttt ccagcctctg ctacttgttc agttcccaat ggtgtcaaaa tcccatgatt
     2821 gattgcatta ttcaaaaata agatttttgc tggttcaata aaaatacttg tcaatggaat
     2881 caaatgggca gataaaatga tctctacacc ttttgccatt gcttgagtca atgcatcgac
     2941 aactggacca atcgcagaaa aacctaataa cgctaatcca aaaccgataa gacctgctga
     3001 aaaattattg actagcattt caaaaccgga tttgatccgt ttttggaata gctgatcaaa
     3061 tttcttgatg gcatatccac caagaggtcc catgatcatc gcgcctagca tcattggaat
     3121 atctgttccg acaatcacac ccatcgttgc aattgcccca acaactgatc cgcggtcacc
     3181 agcaattact tttccgccag tataaccgat caataaagga atcagataag ttagcattgg
     3241 gcttaccatg gtagccaaag cctcatttgg taaataacca tctgggataa atagagccgt
     3301 taatacaccc caggcaatca gtgctccaat atttggcatg accatgcttg ataaagtact
     3361 gcctaatttt tgtaccctcg cttttagcga aatgttgttt ttgggaatcg tccgttccat
     3421 tttgtctctc cctctctcct tttgatactc taattgtatc cgcttactaa aaagagaaat
     3481 agtcgtactt tggcacgaaa ctttgtgcca aaggtttgag tatgtcagca aaataaaaag
     3541 atttcggtat cagaaaactt caattttaaa taaaactgtt attttaattt ttttataata
     3601 tgcaaacaat aacttttgtt agcatttaat ttagatgttt tccattctat tatgttatta
     3661 aattttatat tggaggccta tctatgacat tactgatcaa aaacatgaac atgaaacgtg
     3721 gtaaaaaacg tgtgattcga caattgaatc ttttagtaga atcaggagaa gtagctgctt
     3781 tgattgcccc gaacggattt ggcaaaacaa ctttgctgaa tggcattgcc caactgctgc
     3841 caacaactta tgatcaattg tcccttcaca acatctctcc tactgcttat acagattatc
     3901 gccggtcttt cttttttcta gaatcaacga atcagttatc cgactatcta tcggctgttg
     3961 attatttgac tttgatcaaa tactattggc agagcaaagt agaatgccaa actgttttcc
     4021 aacgattgaa gatgactgag taccttactt tgccgattgg aaaaatgtct ctaggaatga
     4081 aacaacatgt cttgcttgct gcttacttga tcagtgattc atctgtcatg ttattcgatg
     4141 aaccgttgaa cggattagac ccaggaagta ttgatatctt gaatagcctc atcagacaat
     4201 ggcagaaaga ggggaagacg attcttcttt cttcccacgc tatcgcgaat atccaatcga
     4261 tttgttctaa agcatgtttt ctaaaaaatg gagaaatcgt cacagaatcc tcaaatatgg
     4321 aagagatttt agctatttat cgtaaattat atgaggtgta actatgtctt tacttacatt
     4381 tgaacgcaat ctcttactaa aaaacaaagt aaacttttta tttcctctat tgttggtcgt
     4441 gctctttgca ttcccacttt tttttgatca taaacttgct tatacagaat tcgatgaact
     4501 gaatcataac tatgaagaga tgcaacgttt gattgaaacg ttgaaagaag atgagaatga
     4561 gaaagaattt gtggaaagtt tagagaaaag caacaaactg atcgaagcaa tcttacatgc
     4621 aaaaaacaca gggaatgtcc agcaaatggt cgaagcaact tatcattatg aaaaagatat
     4681 actggatcga ctgatttctg gtcaaagaca aggaattcca atcattgaac aacaaaaacg
     4741 tgtcgagttg ctccgttata tgaaagaaca tcagatccaa agatattcta tttttgactt
     4801 gccagcgcat ctccctttag caaattacta cgaaaatatt ttttcaggaa tgatttctag
     4861 ttttttgatt ttatgtataa ccgccttgtt tctttcttcc atcatctctt atgaaaaaag
     4921 aaagcaggta atctctctag tcaatctatt accggatagt atggtaaaga aacatagcat
     4981 ccgttttacc atttattatg gtgcagctat gctaagtctc gtgatgccat ttttgatcgt
     5041 ctctatacta gtaataatca aaaatggttt gggagacttc cgttatcctg taggaacgat
     5101 cattggtcag gagatacgaa tccttccgat gtatgagtat cttttccaga gctttctgtt
     5161 cctgttgttg tgggtgctct ttttaagtac aatcagtttt cttctatctg ctttatttga
     5221 acattctcta gtcaatcttt taggtacact tctttgtctt ttcttagcag agtatcgctt
     5281 gttttcttcg attggatgga tagaatcaat cagtcattac ttgccaactt cttatgttga
     5341 ttttcaaaat gtgatcatag gaggagatat tttctcgcca ctagcttcag aacaggttac
     5401 tttcatgaat ggtatcttga cacttggtat atggagtatc gttttattat tcataggtat
     5461 gggcactatc tatataaaaa agagctatta aaacacaaaa ataatagggg cggtgacaaa
     5521 aaccttgtca ccgtccccta tttcaaataa acggttttct agaataaata gttttcaaaa
     5581 gcttgcatcc gcagtaataa gaacctccca acaaaaatag ctcctcttat ttttatcttg
     5641 gttgaagtta ttacttgatg caaggcagct ttttttactg tgaacattgg ttatatatgt
     5701 ccatgttcaa aaatcatttg gacttcttca atggttttcg catcactgag cgccattact
     5761 tggtcgatgt ctgaacagaa aaaggctaaa tcttggagca ccgctaactg atgttctttt
     5821 tttaaagcca ctacaaataa gagtgtcgcg atttttggtt cctcttttgt tccaaagtcc
     5881 acaccatcag gcacttggac taaatagatt ccttcttcta ctacttcttc atctttgtca
     5941 gtcccatgtg gcaaggctac gaaattcccg atatagacac tcgctttttc ttgtctttcg
     6001 atcattgatt ggatatatgc cggtttgatt cccccttgtt gggtcatcca ctggccgatc
     6061 tcggtcaacg cttctttcca attttgatag gattgatcga gcaatatttt ttctgctggt
     6121 agctgtatca tcttttcacc ttcatttctt tatttcttca atcaggattt tcgctaacaa
     6181 ctgataaacg atttctttat ttcctgagcg gaagatctcg gtgttcaagt cattcatgat
     6241 gattgctcca ctgatctttc ctaaaagaat cccgtctttt tcttggattg gcgaaggcgc
     6301 cagcataact aacatacggg acaaatcgac tggctgtcta tccatccctt caatggtcaa
     6361 cggatgtttc aaattgaaaa tacaaaagat cggtttagaa atcaatgagc tggatgtatg
     6421 gaataacccc atatttgtat gaggaatacc gataggtgct tgttcatatc gcttaagcag
     6481 ccggcgatga accacctctt catccgttac tagtccttca ggaaaataag gaaataagct
     6541 gcgaatcgtt tcggaaatcg tctcaggatt atccagttct tggataaaaa aacgaccgag
     6601 taattgattg atttgatcca tgaaatgcat tgtttcctca taagtatctt ctatcatcca
     6661 ctcgttattg ctgttatacg taattttttg cctttttttc ttctcaatat gcgaaaaagc
     6721 ttcttttagc tgcttgactt catcttctag cagtagcggg gagactaaaa tatattttcc
     6781 accgtatcct ggtaaaatag atgtagaaat aacaacatca tattcttctt gtaaatcgat
     6841 tttttttaaa tcagcaatcc gatagaaatg aatttgttgg atgaagggaa aatacctttt
     6901 caatcgtagt tccaacatgc tagtagaagc taatccactt ggcgaaaatc ctgcaatact
     6961 gatattgctt tctttcggac ttcgttccaa tgaattcgca aaatgaagga ccatataagc
     7021 gatctcttct tcggataatt ttttttcttg aaaaatccgc tctactgctt tacggattgc
     7081 attcgcaact tcctcgtatt gaaccatgat tttttctaaa atcggattgg tcagtgtctc
     7141 ttcttgtaaa acggctcttg aaaacacacc agataaatga gtcaacagca ttttgtacaa
     7201 agtttcatct tcataaaaat ggacattcgt ctcttcactt acttcttgaa tcagttgttt
     7261 tactaaataa gcaagctgtg tatcgaacgt ctcttcaaag aaattctgat caaatgagtt
     7321 cgtgaagtca tttaataatc ctgcaaaaaa gacgatctca tttactggat aaagttgttt
     7381 tgtctcagaa gcgatccgtg aaaacaatcg tttagctgtc tgtagtaatt ctttgtttgc
     7441 cagactatta tatgtctcat ttgtcagtaa atgattttta gtcacacgct ccatcgtcaa
     7501 tgtcagcatc aaaaccaaat gttcaagctt tctatcactt agattggtct ttttttggat
     7561 caattcttcc ccgattactt tgcgtgcaag agatagatgt tgcggatcaa cgaatcgaaa
     7621 aaaataattc agtgatgcat cgaaagaaat actatgaaaa agttcatatt cattgatttc
     7681 taattctaat acattcgctg tcagaagccg gcggtatttt tccggtcctt cgatctcgta
     7741 tccctggttc cgaatgattt ccaaaggcag ttggcgaata ctttcttcca actgtttgat
     7801 atctgcataa aaagtggtat tactgatgcg atatgattcc atgaaatgag caagactcaa
     7861 cggctctgtc gtcagtaaca actcggctaa aatcgcgtgt tgtcgtttag cagtggataa
     7921 gtcattactt ttcccatctg tattttcttt taattgctct aatacttctt ctgatgcctc
     7981 aatgacaaat gagcctctag ctgctttttt caaagaagca tttaccgatt tcaatgagac
     8041 ttcaagatta tctaattcgc ggtaaatagt ccgtttactg accttcaata aattcatcat
     8101 tttttggata gatacaggtg acgggctact gagaaattct gctaataatt gtttttctct
     8161 gggcgataaa tacatcttat atttctccct tcacgagttt ttcgtattca ttcgtagcta
     8221 cccaatgttc aactagaact agccgaggga tcttttcttc tagctgttca gttacagcta
     8281 gttctctttg tgcgatataa atcgtttctt cttggatttt gattttttct attgattctt
     8341 ttgagataac aaactgtttt ttcgcttttt ttgctaattg acttaaaatc gtcatgccca
     8401 tagtttgtga gccgcgtctg ttgtttttat acaaaaatac aatattagca ggcgactttt
     8461 tttgttctgt gatatctgct atctcttttt tttcttcccg ctttggaaat tggatcgctt
     8521 cttttattcg tgacagcaag atatctgttt ccaaaaagtg atccagtaca tagatttgac
     8581 tttgaggtac tttttctctt gcaagacccg ctagttcatg ttgcacgata accagctgat
     8641 ttacttggtt attcaattca tagatagagc tgtatccgac agaaagatcg attttttctg
     8701 ctgctaattt ctttttcagc agggcggctc ccatagcact tgatcccata cctgagtcgc
     8761 aagcaaaaat gacggaatga atgatagatg gttccaagat ttctcccctt tctttgaccg
     8821 ttttgttctc tttttcttta tttggtaatt tcaatagtat cgctgcacaa atgaaggtca
     8881 caaatgtact gattgctatc cctatactta ccccagctag ttgtggataa ggcgcattgg
     8941 caaaaatcac gagtagtgac ccaggcgata caggtgcagc taatcccgta tctaaccatt
     9001 gaaatatcaa cgtgccgctt gccccaccag ccattacagc taaaaataga tacggtcgca
     9061 gcaagacaaa tggaaaatag atttcgtgaa tcccgccaat cgcatggatc atcaatgctc
     9121 cactcgcatt tactttttcc tgtttttctg caaaacaaag gatagaaagt aagatcccta
     9181 aaccaggtcc aggatttgcc tccatcaaaa ataaggaaga gtacccgact gtttgtgaga
     9241 attcgattcc taaaggtgtc aatacaccat gattgattgc attattgaaa aatagtactt
     9301 ttagaggttc taagatcaga ctgacaagtg gtaacagatt cattgtgact agccaagaca
     9361 caacggaggc gagcaacaag tgaacactat ttaaaactgg ttcaataaaa acgattccaa
     9421 ttatacaaat aacgctacca gtcagtccta ctagtaggtt gctgacaagc atttcatatc
     9481 cagccttgaa tttcacgtgg aatctagaaa caaattgttc atatacgatg ccggcaagcg
     9541 gcccgataat catcgctcct acgatttgtg gagcattgga acgagcgatc aaccctaaag
     9601 aagcaattgc accggcgact gccccttttt gtccccctac cgatttcccg cctgaataac
     9661 tgatcaagat gggtaaaagc agctggatca tccaatggca tacctcttct aatgtggtgt
     9721 gcaaatcgcc agacacacct tttgttgcta atgacaagat tccccaagcg ataaacagac
     9781 ttagatttgg catgatcatt tcatttaagt gatgtccagc ttttctcagt tgtttcatag
     9841 acacgcgact gctgttgttt gctttccatt tgtattccat ctttttcacc atacttctat
     9901 ttattgatgg acggatttta tgtagaaaaa gcagcaaacg aaaaaccgtc tgctgctttc
     9961 agctatctgg gaactatttg cctggttcag tcgcaatgat tgctagttca ccttggaccg
    10021 cccactcaga aacgccattt ggaataatac agcttgttcc tttttctaat ggatatgttt
    10081 ttccgtcaac gacaaggtct cctgctcctt cgattaccgt catcaatgta taaggggctt
    10141 gttttttgaa agatgtgatt cctttaatat cccactcata tacattgaaa aactcagttt
    10201 ctaaataagt gacgatcgat gaattccctt ttcggacttc tttgatttgt aattctggtg
    10261 ttttcgcagg gacagttgtt acatcgatcg attgttggat atgcagctct cttgtttgtc
    10321 cttgcgcatc ttttctgtcg tagtcataca cgcggtaagt cgtgtcagaa ctttgctgtg
    10381 tttctaaaat catgattcct ttaccaatag catggatcgt tccgcttggt acataaaaga
    10441 aatcaccttt tttaactggt actttcttca aaaggtcatc ccagcgccca tctttgatca
    10501 tctcagctag ttcttctctt gtctttgcat gatgaccata gatgatttct gcaccaggtt
    10561 cagcatcgat gatataccag cattcagttt ttcctaattc accttcatgt ttcatcccat
    10621 aggcatcatc tggatgtact tgtacagata gatcatcttc tgcgtctaag atcttgatca
    10681 ataatggaaa cactggttct gaaggatggc caaacaattc cttgtgttct gaccatagtt
    10741 catctaatct tttccctttg aattcgccat tttctactac actgacacca tgaggatgcg
    10801 cactgatcgc ccaatcttct ccgattttat cgttagggat atcaaaacca aagactgaac
    10861 gtaaacgact tcctccccaa attttttctt gaaaaactgg ttttaaaaac ataggttcct
    10921 gcataattca aactcctctc atttttcata gctattatag cattatttcg gtaataccgc
    10981 tttctctttc aaaaagtttt caacaatttc atctcgacat atgagatact ccgcacgatg
    11041 atcgacagga tgtacgcgat ttgacaaaaa tatcaacgct tcttgtgttt ttatatcaat
    11101 caagaaaaac gtacctgtat aaccagtatg aaaaagaatc gcatgaccgt cttctacatc
    11161 cttttttaag tcccatccta aagaacgata gccatttttt ttcggtgttt gatcttgcag
    11221 taaagaatca atcgtctctt cttctaaaaa acgaccatta cggatttttc ccttgttcaa
    11281 atacatttgg acaaaagtaa tgctgtcttt caaatcaata aagagacccg cgttacctgc
    11341 atgttcagcc aaaactcttg ctttcggatc atgagtttgt ccacgcaaaa cctcacccga
    11401 aggcagttgt tctgtgggaa cgattttttt ggaaggaaaa ggaagaaata agctgttcat
    11461 cattcctaat ggttccaata cttgttcttg aaagatttcc actgcagttt cttggtaaat
    11521 ttcctctagc atcaacccaa gaagaatcgt accggcatct gtatatttta cttcttttcc
    11581 tagttgctca cctggttcta gcttcaaata agcggcgatc aattcttcct gagatagctt
    11641 atctctgttt ggtatccatg ttttgatatc agaagtatgt gtcagtaaat gacgcaaagt
    11701 gattgtctga ttttcaaatt caggaagata tttatgaagc ggttgatcga gttctatctt
    11761 tccatcttct aatagacgta aaactaatga agtggttgca acgactttcg tcagtgaggc
    11821 tgcatcaaac aacagatctt ctgtcatcag ctgcttttca ggaacgactt gggcaaagcc
    11881 ggctgtaaat gtttctactt gattttcttt tatgaaggcg actgctacac ctggataaaa
    11941 tccttcttcc atctttttca aaataagctg tttcgtgtgt ggatacatct ttttctcctg
    12001 cttttctatc agattcttac agtccaagct taaagcttaa tctatgagga atcaaccttt
    12061 tttacacaaa aaaactgcgc gaaaaaccgc gcagtttccc ccggtatact attttctctt
    12121 tctatctcta gaataagcga tagtatgacc gttcataaaa tgacgagaca tgcgacaatc
    12181 gttaagaaag aaaaagttaa gcgtcgcatc gaatgtcagt tttattcttt tcttttggct
    12241 cactgacgaa ccaccattcg attcctatag catcatagat tgtgagtact gtgtgctttt
    12301 tgtctaagaa gaaatcaact gatagttgct gcaagtgagc aatcagtcct tccatgcttt
    12361 cagtatcgat catgaatttc agaaaatcaa gtccaatcac ttcatctgta ggcaaatcaa
    12421 ttgcgcctcc gctagcttct gtcaaaccaa catggaaatc tccttcattc aatacatgga
    12481 tgccctcttc ttcattatgt accttcaaac caagtacatg attaagaaat tggcgttctt
    12541 ttgttaagtt agtaacattt aaatggattt tttcaaaata agaacctgtt gatagtttac
    12601 tgaatttttc ttcagatttt cttaataatg cttcttgatc cattgtttct ggaatttctc
    12661 tttggtcgtt cttattctct tcatggtaaa tttccaattc attctcttct gggtctacga
    12721 gcaaaatccc catacgtcca tgatcttcta aagcttcttt gattggataa ttcattttac
    12781 ggatacgaca aaggatatct gccatttctt ctgtgctagg gataatcaat gaaaaacggt
    12841 tcagcttttt gatcaccccc atgtgatcat tcgctctagg actttcttcc agcagcaaca
    12901 tttcacttcc agcttcttct gttcctaaaa tggctaattc gttttcttct cttttcaaat
    12961 caaagccaac aacgttcttg taaaaatcaa tcattttatc tcggtctttc acccgaatgg
    13021 ctacactttt taaataggtg gcagccccca attgaaaatc tttcatattt cttgctcccc
    13081 tctacgtcaa gctttatttt aacgatggat tcttcttctt tcaagcaata actttgattt
    13141 tgttaaaaaa aatgtgagaa aattcgcatt ttgcttgttt tttgtaaatt aatgagtaaa
    13201 aactcttata aaaagaggtt gtgaaaaagc tgttctgcat caagtaataa gaacagccaa
    13261 acaaaaatag ctcctcctat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt
    13321 tgaacaccgt ttaaggaaga ggttgtaaaa tcagcggttt gacctgagta ttagagatac
    13381 aaaacggaaa aatagcttct catattttgc cgttttttga gctaataccg aaggacagct
    13441 gattgaacac cgtttattcg gaaaaaggga ctgtgacacg acttttgtca cagcccctaa
    13501 aaaaaataat aaatttgtac tattctatga agcttcttct tcagaaaact gactgttata
    13561 aagatctgca tagaatccgt ctttttccat caatgtatcg tggtttcctg tttctacgat
    13621 cgaaccatga ttcatcacaa taatgttgtc tgcatcgcgt attgtagaca agcggtgagc
    13681 aacaacgaaa cttgtccggt tttccaatag acggttcatc gctttttgaa tcagtatttc
    13741 tgttcgtgta tctacactag atgttgcttc atcaaggatc aggacatctg gatttgctaa
    13801 gaatgcccgc gcaattgtga ttagctgacg ctgcccttgc gaaatattgc ttgcatcctc
    13861 gtttaataca gtgttatatc cttctggcaa tttacgaaca aaatcgtcta cgtgagcagc
    13921 tttagcagcc tcaatgattt gttcgtctgt tgcatcgtcg ttcccatatt tgatattgtc
    13981 atagatactt cctgtaaaca gccaagtatc ttgcagtacc attgaaaact gtgcgcgcaa
    14041 ttcatcacgt gaaagatcac gggtatctac accatcgtaa cgaatactac ctccagaaac
    14101 atcgtagaac cgttcaagaa ggttgatcag tgtcgtcttc cctgcaccag tcggacctac
    14161 aatagcgacc atctcaccag gtttgacatc caagttaaaa tcagtcatta gcaagttatc
    14221 tggtgtgtag ccgaattgaa cattttcaaa acgaactttg tatggtgtat ctttttcttc
    14281 tggaaggcca gatttttcat tggacatctc ttcttcatcc aacacttcaa atacccgttc
    14341 ggctgaagca actgttgatt ggatagtgtt catcaaactt gcaagttgag tgattggttg
    14401 agagaactgt gttgtatatt gcaagaacgc ttgaacatcc cctaatgtca tgttcccatt
    14461 tgcaactttt actccgccta gtacagcgac gaacacatag cctagatttt taacgaaatt
    14521 catcaacggc atgatgattg ccgaaataaa ttgagctttc caaccagcgg catacagatt
    14581 ctgattttct ttttcaaata cttcctggtc tttttcagta tgattgaatg ttttaacaat
    14641 ggtatgacca ccatatgttt cttctacttg gttattcaat aaacctaaac ttttttgctg
    14701 atctgcgaaa aacacttgtg atttcggcgc tacgatcatc acgatgatca agcttaaagg
    14761 gatcatcaat aacgcgacta acgtcaattg ccagctgatt gaaagcatca tcacgatgac
    14821 cccaatcaat gtgactgcac tagttacaaa ttgagtcaaa ttttgctgca gcgtgcttgc
    14881 gatgttatcc atatcattga ttgctcgaga catgatatcc ccatttgtat gtgtatcata
    14941 ataggaaatc ggtacacgat tcattttggc ttccaaatca tgacgtaatt cataaactgt
    15001 tcgttgggaa acacgtgtca taataaattg ctgtaaaaag ttgaatacag cagaaatcaa
    15061 atacatcacg attactgtcg caatgatctg cgcgatttta tcaaagtcta tcggaaattt
    15121 tgttacttgt tggccttgtt gcatctgttg agcgccagcc attacacctt tgaatatttc
    15181 tgtggttgct ttccccaaga cctttggtgt ttggatttgg aagatcacgg ctgctattgc
    15241 tagtacaaat acagcgatga tcgcaaccat acgtttagac atatagccaa acaatcggcg
    15301 taccgttccc cagaaatttt taggcttttc accttttaca ccgagatttc tgccaggtcc
    15361 accatgtcct ggaccgcctg ctggtccatg agagggacgt gtgtttgttt tactcatgct
    15421 aagtcctcct ctcttagttg tgaatgaacg atttcttgat aagtttcgtt tgttgctaat
    15481 agttcttcat gtgttccttt gccaaccagt tttccttcat ctagcacaag gatcatatct
    15541 gcatccatta ctgtacttac tcgttgagca actaaaacgg tgatactttc tttcatattc
    15601 gttttcaatg cttggcgaag attggcatcc gttttgaaat ccaacgctga gaaggaatca
    15661 tcaaacacat agatatctgc tgttttgact aatgcccgtg caattgccag acgctgtctt
    15721 tgtccaccag agaagtttcc tcctccttgt tccacatggc tatctaagcc atcttccatc
    15781 tctgaaacaa aatctttagc ttgtgcgatt tctaatgctt tccaaatcat ttcatctgtt
    15841 gcatccggct taccatactg catattgtct cggatcgttc cagagaacag aactgctttt
    15901 tgaggaacaa agcccattaa ttctcgcaaa ttatattgag tcatgtcact aatgtccgtt
    15961 ccatttattt ggatcgaacc agattcgatg tcatataatc gagggatcaa attgactaag
    16021 gtcgttttac ctgaaccagt cccccctatg attgcgacga tctcgcccga cttggcttgg
    16081 aaatcaatat cttccaatgc aagtttttct gctccatgat atcgataatt gacatgattg
    16141 aaggccaatg ttgcgttttt tccagcaaaa gaaactgttt taggattttc agggtcatgg
    16201 ataccgattt tttcatccaa cacttcatta atacggtcag ctgaagcttg tgcacgaggc
    16261 accatgataa aaatagcgga aagcatcata aagctgatca agatctgcat cgcataagtc
    16321 ataaatgcaa tcagattacc gacttccaaa gtcatatctg ctatgtagtg tccaccaaac
    16381 caagtgattg ctacgtttgt accgctcatg atcaatgtca tcattggcat catcaatgcg
    16441 acgatcgtat taactttgat tgccgtattt gtataatctt tattcgctaa atcaaaacga
    16501 ttttcttcaa agcgtgtctt atcgaatgct cgaatcactc tgacccctgt caatccttct
    16561 cgaaatacca ggtttaaacg gtcagttttc ttttgcatac ttttgaataa tggaacagca
    16621 aagtacatga ttccgccgat caaaataatc attactggga tgacaactaa gaagattttt
    16681 gtcaactgat gatctttttg ataagcaagt atgctcgcgc caatcaacgt gattggtgca
    16741 ttgatcatca tacgtaaaaa catttgtgta accatttgga tttgagtcac atcattggtc
    16801 gttcttgtga tcaaagaggc cgttccatat ttatcaaacg catcttttgt cagactctct
    16861 gattttttat agacatccgt acgcaattgc ttacccagtt tctgtgattc acgagtagca
    16921 aaaaatgtat ttgcgatagc agctaagata ctgatcaaag aaaagccgat catcacaaaa
    16981 cctgtatgcc aaatataatc gacatctcct tgcgctaccc ctttatcaat aatattggag
    17041 gtaagtgtcg gcaaatataa atctgccagt acttggatca ccatgaaaac tgcagctgca
    17101 attgctgaag tcaaggagat ccgttttacg atttttagca tctagttccc ttctttctat
    17161 ttatatactc cgtttttcag ccaagaaagt ttcaaattga attcactgat tgcttgctct
    17221 actgagtaat cttcagatgt tgaaaataag cgatacgaat gcgcaattgt tgtaaataca
    17281 gtattcatca ctaattggat cagtaattcc aattcatgat cattttttac tttcagcttc
    17341 gtccgatcga tcaattcaag caactctttt gcatcttgtt tgtgttcttt atgtggatcg
    17401 tgaggcgttt tttggcgact cgtatgagga gcgacttttc ttgaggcacg gtaatccatg
    17461 ttcataaaca agttacgata aaaagaagca ttctcgcctt ccaaaatctc ataaatcatt
    17521 ttagaaaaat aggattcgaa tcctttgaat agatcaccat cggattcttt cattagttgt
    17581 aacatatctt tagagctgtc acgtctcatt gtctcaaagt aataaaaata aagatcctct
    17641 ttatcttcaa aatactgata gaaactgcct ctagggatat ccgctaattt gacgatatta
    17701 gcaatcgaag cttcttttaa gggtactcta gaaaactcga ttctcgcagc ctcgattagt
    17761 cttttttgtt tttctttagg caaatggaaa aatgtctgtg tcggcatatg gatcctcctt
    17821 tctttcaaga tgacacattg tcatatgacg ctgtgtcatt ataacacctc ctacctgttt
    17881 tgcaagacat ttgcatagtt tttttcatta tcatccgata cattaaaaaa gtgataagag
    17941 gaatccttcc atttgaatta atgagagttg cccattaaaa tagccacata ctaaacaaag
    18001 gatgagataa atggcccaat caattagtgt ccaagacttc aataaattgc ctctcgatgc
    18061 tgacagcatc gttttagata caagaaatac cttagattac acaaaaaacc acttaagcca
    18121 ctcgctttct atccccgctg ctatcttgcc aagacaatta aaaaatctag atccaaagaa
    18181 actttaatat attctaagct atacaggcag gcgatcagaa gcattagccg atcaacttac
    18241 tgctaatggt tttcgtgctg tttatatcat tggtgggatg gaagctcttc agtcgagtgt
    18301 tgcttgaata ttgcttgtta gattcaaaag aggctgtgac aaaaaatcgt gtcacagcct
    18361 cttttatacc ctgtcttttt ttagttattt attcttcaac cttatcaata tgacttgata
    18421 gccttttctt tttctcatag ttataacaat catagcaata aaaggagaag gtaagcatat
    18481 ggcatctgtt ttagtagtca aaggtcatcc cctaactgca gaagaatcgc gcacagttaa
    18541 ggcattgacg tcttttttaa caagttataa agaaaatcat ccagatgatg aagtgactgt
    18601 tttggaactt tatcgcgatg atattccgga aatcgatgaa gaattattat caggttggga
    18661 agcattacgt gctggtgcag aattcacttc cttatcagaa agtcaacaac aaaaaattgc
    18721 tcgtttcaat gaattgactg atcagttcct tgctgctgat aaaatcgtta tcgcaaacgc
    18781 cttatggaat ctaaatatcc caacaaaatt aaaagcttgg ttcgataccg tcaatgtagc
    18841 tggaaaaacg ttccgctata cagaaaacgg gccagaagga ttagtgacag gtaaaaaagc
    18901 actgcacatc caatctaatg gcggtgtata caacggacaa gactttgcct ctcaatatgt
    18961 aaaaggtatt ttaaactttg taggcatcga tcaagtagat cagctattca tcgaaggaat
    19021 cgattatgac cctgaccgtg cagatgagtt gatgcaaaat gcattagata aagctgctgc
    19081 tttaggtaaa tcattttaaa aattgagata aatgcataca aaagagacag aggaaaaaat
    19141 cttcaaagca gcatttgtac cttggatatt ttcccatctg tctctttttg ttattctttc
    19201 tgctttttca acggattttc ttcataaaga gaagagattg ttgtgtacca ttcaaaaaca
    19261 tgagtaatca ctactttagc tgctgcataa acaggaatcc ccaagatcac accgatgatt
    19321 ccgaacaatt tcccagaagt cagcagaact aataaaatcg ttactggatg gattgctaac
    19381 tgattcccta gtactaatgg agagatcaag cgtccttcta ttgtctgctc tactgcaaaa
    19441 acgatcagta ctttgatgat catgaatgga cctgctacaa tggctaaaaa gatagccgga
    19501 atcatcgcta aaaatgatcc taagtaaggg atcaggttca aaaaacccgc aataatcccc
    19561 aacgtgacag catactctaa accaatgacc gcaaaaccaa tcataaacat gattgccaca
    19621 gcaaaagcca cagttagttg tcctcttata taagaagaaa cttgactatt catttcactc
    19681 agcacattca acgtcggttt ttgcatgcgt gtcggtaaaa atttgacaaa ataaggtgct
    19741 aattgtttac cgtctttcaa tagataaaat aagataaacg gcatcgtcag cagagccact
    19801 aaaatagtcg ctaccgcgcc gacaaaactt ccaagactct gaactgtact cttagatata
    19861 tcttggatca tatcgcctgc cgaattcatg aacttatcac ctgctgtttc caactgttcg
    19921 cgaaattggt tgaacagcgg gtcccgcaaa atctcggtta atttattatc aatcgtatct
    19981 acatattgag ggaagttact gatgaagctc actgtttgtt cctgaatctt agggatgatc
    20041 actacgctcc cccatgcgat tagtgcaaca accaaaacaa acagcccaat gatactgtaa
    20101 agccttggta cttttcgctt ttcaaagtaa tcaactaccg gattcatcaa gtaatacaag
    20161 attcctgcta aaatgatagg cagacctacg attgctaaaa attgccagat tggtgcaaac
    20221 aaatatgaaa cttttgtaaa taaaaagacg atcagcaata ttaacaatac aacaagtaag
    20281 gctgtgacta cttgattatt taaaaaccag cgccaaaacc acgataccgg tctgttcttc
    20341 ttattttttc cttccataat tcctcctgtt agttataaaa aatttggctt cccaaaccaa
    20401 tagcaggcag tctatgcgga tgaagataga ttccatttgc aatttgtcct tcttctggac
    20461 aagcatcaaa aatcaatgat acgtgagcta ctgtctctaa attcccattg gccatcggac
    20521 cgacataatc gatcgtatat acctgatcat caaaagcaat tgttccgcct gctttcaaag
    20581 aaaaaggttc gtcttttgat acttcttgaa tcaccgaata ttttcgtaag gcagctgttg
    20641 ctgttttatc gaacaaaatc agcatgggtt cttccttgtt tattgcttct gtcccaattt
    20701 ctgtaatctt tgcctgaatc attgcactct ctcctttaat tgctttcaaa aacagtataa
    20761 cacattctca ttctttagcc gtgtggaata attatgtgat agaataaaaa cgaaaactat
    20821 ttcattacaa ttaggaggaa tcagctcata tgatcgaaaa gataatttta ggaacctata
    20881 cgcgtcgcga aagtaaagga atctatacga tcgaccttga tacagaaaaa gaagaattag
    20941 ccaacctttc attagctgtt gaagaaaata gccctaccta tgtagcaaaa agtaaagctg
    21001 gcaatcttta cacagttact agtgtggatg gattaggtgg tgccggtgcg tacgataagg
    21061 attttcattt tttgaatgcg gtaacagagt ctggcgctcc tttgtgttat gtagcggttg
    21121 atgaagcacg tcaattacta tacggggcga actatcataa aggtgaagta aatgtctacc
    21181 atatattagg agatggcgaa ctgaaagcag cagattcaat attccatcaa gaagcgacag
    21241 gtcctcataa aaaccaagat catgcgcatg tccactatac ggatctgact cctgaccaac
    21301 gattagtcgt atgtgatctt ggtacagatc gtgtgtatac ttatgatgtg tccgaaaacg
    21361 gcaaattgaa tcttgtaact accttcactg cagagccagg aacaggccct cgccatcttg
    21421 tctttcatcc aaatggacaa ttcgcttatt tatttggtga attagacagc acagtccgcg
    21481 tgctttctta taataaagaa acaggtgctt ttgaagaatt acagaaaata tcgaccttgc
    21541 cagaagaatt cgacggtgaa aatggagggg cagctatccg catttcaaat gatggcaagt
    21601 tcctttatgc ttctaaccga ggacataact cgattgctgt attcgcagtt tttgaagatg
    21661 gttcccacat tcaaaacaag caaatcatct caacagaagg ggattttccc cgcgatttcg
    21721 cactagatcc aagcaataat tttgtcgtgt gtgccaatca gaacaccgat aatctgacat
    21781 tatatcgccg tcatcctgaa acaggattac tggaattact gaaaaaagat gtctatgtac
    21841 cagaatgtgt ctgtgtttat tttgatcgtt agtaagaaaa ggagaatgaa atgaatcagc
    21901 aagacgtatt agacagacta cgggaagaac taaatattcc tttctttgat gggaaaatcg
    21961 aagataaaga gtatagcgaa gaggaatatc agaaactcaa agccgattta cagaactact
    22021 ttgaacaata tgtacagaat gtagaaaact aatcagcttt ccatactatc tgaaaagaac
    22081 atcaggacaa gacttttccg tctatcctga tgttcttttc tacaaataaa aaaccgccga
    22141 gatggttaga ctcgacggaa aaggagtatt tactcgattt tgagtaagta caaggttgtt
    22201 gttggttata ggtatgtcat tatcataaag gattttgatc actctatcat aaaggtaata
    22261 ttacatttat attagataac tctagttttt attgttatca aagatttctt ttattttttc
    22321 aacaacaaat tagtcatttt ttggatggca gctgtcaatt ggtctgtcgc ttggtcttgt
    22381 tttgcttcag atgtattgaa tagatcttca tctacccctg attcaagatc gatactttgg
    22441 atcatttctt cacagcctgc tacatatgaa agataagctt tttcaaaatt tttatgaatg
    22501 cccattgctt ttgctggtgg acgcaaagta ctgactttct taagcattgc ccgatatttt
    22561 tttgttcctt cttcaaataa caggatgatc tcttcaagag tcgatttgtc cagttcactt
    22621 gtttttcctt catcaattgc gtttctgatc acttcatatt tcggatgcat tccttctccg
    22681 attgcttctg tttccttgac gatttgatcg atggactgca cataatagcc aatattcggt
    22741 aacatgttcg ttttcctact ttctccattg ttgttattat ttattctact tgtttttatc
    22801 ctcaaatgac aagtacttga aaaaatttaa tggtttctat acagctcgcc attcttattc
    22861 gtgctcaaag aaaccatctg ctaaactata ttgtttccct gcgacaatgt catattggat
    22921 caattgatat tcgtcgtaaa tctcttgttg cgagcgattg aattgcgctt ctttatacca
    22981 ctgtccgttt tgatagtaca gttctcgttc aaacgccgga agttcctgtt ctaatgataa
    23041 aagcagctga taaaagccat ttgttgtctg attcgtctgt tccattagat tcgctgcaaa
    23101 ataaaacgga ctggtgattg catcgtgagt cgtttgcttt tctaattctc ctttactgtc
    23161 gaacataaga aattgtgttt catgcaatgt ttgtttgtca ttttttgctt ggatcgtatc
    23221 tgaatagatc cctggaagat gatcccccca aaaaacaact aaagtccttc tagaaagatt
    23281 cttcaattct tccgtgaact gcttcagtgc cgtgctgcta taggaaatat cttgcagata
    23341 attctctaag tcaagtgtcc cacttccatc tgaagttttt gcaggatagt ctagattatc
    23401 atactttcca tcgtagggca tatgtgtctg catcgtgact aaatgaatga actgaggtgt
    23461 tttttcttcc ttgagaagtg tcattacttc tttgtaagct gactcatcag aaatatatgg
    23521 attattctct atcgtatccg tataggtcat cgtacgctcg ctgatgaact ggtcaaatcc
    23581 taatgtctga taaacatcct ctcttttata catcgaagta ttgtatggat ggatcgctgt
    23641 cgtctggtat gattgtgcgt ttaacgctga aacgatagaa ggaagctgat ccatttttgg
    23701 tacaagcatc gtgtaagggg tggtgagttg cgcattaaat aacgccatag aaaaaccagt
    23761 caatgcttca aattcgatat ttgctgttcc accgccatag ttttgagaaa gcatattgcc
    23821 actatatgtt tgatcagcta cttcataata atctgccaat ggctcaccag atacttctac
    23881 gccgtttaat cgactaggat ctgagaaact ttcactcatc acgaacacga tgttcggcga
    23941 ctcttcctct acagttttat ttttttcatc ggctagcttc tggtattttt cagtgatttc
    24001 tttgatcttt tctttcgaat atccttcagg ttcatccatt ggttctacct tcagattgta
    24061 caaaaaccca ccgataaaac cagtgttata gtagttcatt ttctggctgt aaggtatcca
    24121 tagtgccgtt ttattatatg cttttcgcaa caaattatcg ggattgttga aattactgat
    24181 ataccctagc agtccaattg ccacaagcag tgtcgttaat cggatcaatt ggaatcgcct
    24241 tccttttttc aggcttcgaa acatgtacca gcaaaacaat cctatcacgg ttcctgcggc
    24301 agctaagatc actgtaaaca gcatagtgcc ggtcatatct ttcagcaatc cgatttcagt
    24361 gatcatcttc aaatcgtctg gataaatcgg ttcttgccga taactcattt tcatataatt
    24421 tgcaaaacct aatacaccga tggctacgac atacgtaagg gaacctaaag ggacagatcc
    24481 tgctagtgca atcagaaaaa taagaataat cagcaagacg agacaggcta agaagaattt
    24541 ttccgtatgc caagaaaaag caaatttcaa cgcaaggtct acggatagat cattttgaca
    24601 ccactgcaaa aataaattac taaaaacaac aagaaaaaag atactgatga ttgctgctgt
    24661 tccttttaaa atctttttct gtttggtcga aagtctgctt atatatcttt tcaaatgctt
    24721 gctccttcat ttctatcaat aaaagaatgt tgcttctctt attttagttg tacgaaattc
    24781 gaaagtaaag aacggaaaga agaattaatg aaatccaaat attctctttc tttatggcct
    24841 ttctggtttc tttaataagc ggacctttcg tactccagaa attttttcta gctgttgttt
    24901 cacttgattg agctgttcaa aatcagtact gtctatgtca atcaatatgt agacatgctc
    24961 attcttatgg ttacgcgata tatctgcgat cgctagctcg ttctcattca gcagagaaaa
    25021 tatctctgct aatatattgg ttttcttttg ataaaatata gtgaatcgaa acggcgcttg
    25081 gaaaaacatt cgtgcggatg gataattgac cgcttctcta accgtaccga acaaaagata
    25141 atcttttaag gcttcaactg ccaaacgtcc gctgtctgcc aaagcttcct gagtcgatcc
    25201 ccctagatga ggcaacataa gtatacggtc attttctaag aactcttctt ctggaaaatc
    25261 agtcaagtat ttagccagat gttgtttttc caatgcttgc ataacagcat atttatcaac
    25321 aatttcactt cttcctacat tgataagtac agcatctttt ttcatttttt ctatattcgc
    25381 ctgatcgatc aatccttttg tatcttctgt caacggcagc atgactacga tgtaatccga
    25441 ggtagaaaga actgtttcta aatctgcttg ccgaacataa tccaactggg catcgcggat
    25501 agaataaccc aagacatcca tccctaagct atagcaactt agcgctactt ttgtgcctat
    25561 cgctccaaga ccaagaagac cgatggtttt gccttgcaat tctcgtccca cataagcact
    25621 tcttttgttt tctgcctgtt ctaaaatatt aggacctgtt agtgtttgta ccatacgact
    25681 tgcttcgatt atcggacggg aagataagag caaacagcac aaaacaagct cttttactgc
    25741 attagcattt acacctggtg tattcatgac gatcgtcccg ttttcagaag ctttttcaac
    25801 gttgatcgtg ttcaccccaa caccagctct tgaaattgct agcaaatctg gtgtaagcca
    25861 ttcatctttc actttcgtac tacgaataac tattccttcg gctggcaaat catctattat
    25921 tttgaaatat tccccttgta acttttctat ctcttgttct ggaatagcat caatcaaatg
    25981 aacgtgatac ataaaacccc ctccttacta acaagtatct cgaaatttct gcaattagac
    26041 aactgtttac catttgactt cctagaagca aaaagagcag ttagagcaga gtaggctgag
    26101 tgataaaaat aaggctatga caagttactg ccataagcct tattttcgag agcaaaatat
    26161 tgagggtgag atatcttgat aaatggtgtt ccgttagctg acattgataa taagactaaa
    26221 tttcaaaaaa gttgaaaagc aaatttcgtc aatctcttct tatttcttaa aactaagtgg
    26281 ctttttcaca acctcttttt atctaataac cactgtttcc aactcaacta attttgccca
    26341 cgtttcaatt tgatctgttg ttagatttag cgagacaacg gtatgatgac cgccacctgc
    26401 ctgaatccat gaatggacac cttcatggaa attcggttta gttttccata acacacgtgc
    26461 aacaggtaaa ttaggtgctt cagtcgttgg ttcaaaggct tctacttcat tgatcagcag
    26521 tttataatgc gtaccgaaat ctgccatcga tacgactacc ccttctcctg ctttcccatc
    26581 aaatacaaga cgcgccggat cttctctatc tcccattgat aaaggagaaa caacgattct
    26641 tggtttcgtc gcagcaagcg tcggatctac ttccatcata tgggattcca agattgcttc
    26701 ttggccacta gctagctcgt aagtataatc ttccatgaat cctgtatctt tccctcgagc
    26761 catgattttc agcaaccgat caatcgctgc agttttccag tcgccttccc cagcaaaacc
    26821 gtatccttct gccatcaaac gttgtacagc tagtccaggt agttgtttca ttccatacag
    26881 gtcttcaaaa ttagtcgtaa aagcgttata gcctccttct tctaagaaac ggcgaatacc
    26941 gatttcctgc tgagcttgta cttttacatg ttcctcccat gtcttttctt cataatcacc
    27001 atagtcgaag gtatacaatt ccttgtactc ttcaaataat tgatcgactt cttcgtctga
    27061 tacgcgatcg attacttgta caagatctcc gataccaaaa taatcaacag tccaaccaaa
    27121 ttgaatctgt gcttccactt tgtctccttc tgtgacaccc acgtttctca tgttgtcacc
    27181 aaaacgagcc acttttattc caaaactttc attataggct actgcaacat ccatccaatc
    27241 agcaatctct ttttggatct caggtcgttt ccagtagcca acgacgattt tattttgttt
    27301 atttaatcga gcattgatga acccatattc gcggtcacca tgagcggatt gatttaaatt
    27361 catgaaatcc atatcgatcg ttttccaagg aatgctttcg ttatattgcg tagctaaatg
    27421 aagcaatggt ttttgtagaa gctttgtccc gcggatccac atttttgctg gtgagaaagt
    27481 atgcatccaa gtgatcacac ctgctacttc ttctcgataa ttgacctctt tcatgatttt
    27541 tgtgatcgta tcagcagtaa ctgctaattc ttgaaggcgg attggataag gcaattggcc
    27601 attttcattc agttcatcga ccatttcttg tgcatgtttc tttacttctc gcagtgcttc
    27661 ttccccatat aaatgctgtg atcctacaac aaaccaaaat tctttttctc caatattcaa
    27721 cataattagc cactcctttt atttgttttg tccgtaatac gcattttttc cgtgttttcg
    27781 taaataatgt ttatctaaaa tccgttgagg cagctcttct gaaaatgaat tgagctgtct
    27841 ggtaaataaa ttcatcttgc atacttcatc tagtacgact gcgttcatta ccgcactttg
    27901 cgcatctttc ccccaagtaa atggaccgtg tccgtgtaaa agtacccctg gaattgctaa
    27961 gggatcaatt ttgcgttctt tgaatgtttc tatgataact tttcctgttt catattcgta
    28021 cccgctgtcg atttcctgtt gtgtcaaaaa tcgagcacaa ggtaccgatc cataaaaagt
    28081 atctgcatgc gtcgtcccca tcgcaggaac atccaatcct gcttgtgccc agatcgtcgc
    28141 ccatgtcgag tgagtatgga cgattcctcc gatttgagga aatgaacgat ataaaacagc
    28201 atgagtaggc gtatccgaag agggattgag tttaccttca atgatatgat tgtccaagtc
    28261 cacaacgacc atgtcgtctg ctgtcatctc ttcataactg actccgctag gtttgataac
    28321 gaaatatcgt gtttcaggat caaaagcgct cacatttccc catgtatatt tgacgagtcc
    28381 gtgtttaggc aagtcaagat ttgcttggta tacttcttct ttcagttgtt ccagcatttt
    28441 ctatcactcc tttttcttgc aattgatgaa tcgctgtttt ttcaatgtcg atcccctcac
    28501 ggtaacgtct cataaatatc tgatagcctg ctatttcttc tgctgaaggt gtgatggtga
    28561 ttccttggtc ttgtccaaac acgtcttctg ccaagaagtt ttctaaagac ttcccatgtc
    28621 gatccatcat ataggctgct aataacgcga ttccccacgc tccaccttct ccggctgtgt
    28681 ccatcactgt aactggtgcc tccatagcag atgctagaat ccgctgtcca acttctggtg
    28741 ttttaaaaat ccccccatgc cccactaaac gatcaatttg gacattctca gatttcaata
    28801 tatccattcc gattctcatt gcaccaaaag cactggctaa atggatccgc atgaaattcg
    28861 ctaaatcaaa acggctacct ggtgtacgta caaataatgg ccttccttca tttactcctg
    28921 taatgttttc accggaaaaa taaccataag aaagtaatcc cccgcaatcc gtatcgcctt
    28981 ctagcgcttt gttgaataat accgtgaata atttatctct gcttatctcc atacccaaag
    29041 aattggtaaa ttcttcaaaa atactgaccc aagcattgat atccgaagag cagttattcg
    29101 tatgaaccat gcctactagt tctcctgaag gtgtagtgac catgtcgatt tccggatgga
    29161 cattttctag ttctttttct aatacgatca tagcgaaggc ggaagtacca gccgaaatgt
    29221 tccctgtccg tttggctaca ctgttcgtag cgaccatacc ggttcctgca tccccttctg
    29281 gcggacaaac cgggattcct ggtctcaaat ttcccgtagg gtcgatcaga taagcccctg
    29341 attcgcttaa cttgccagct tcttctcctg ctactagaac tttaggcaaa atgtgatcca
    29401 agtcaatcgc tacgtgcgct ttttcgatta actgaccaaa aatatttttc atttcttgat
    29461 ggtaggtttt cgttgaagga tcgataggaa acatgcctga tgcatctcct acgcctagta
    29521 ctttctcacc agtaagctgc caatggacat aacctgcaag cgttgtcaaa aaattaattt
    29581 ctttcacatg ttcttcttta ttcaaaatag attgatacaa atgagcgata ctccatctct
    29641 gcggaatatt gtattgaaat ttttccgtta atattcgttc tgcttcttca gtgattgtat
    29701 ttcgccaagt acgaaatggt actagtaact gttccttgct atcaaatgct agataaccgt
    29761 gcatcattgc actgaaccca atcgacccga ttgtcgtaag attctcgcca tagatttcga
    29821 atacttctgc tgccattttt cggtaactga cgcgcagtcc tttccaaata tcttctaatg
    29881 aataggtcca gataccattt tctagtttgt tttcccactc ataactacca gcggcaatag
    29941 gagtaaaaga tgaatcaatc aatacagctt tgatcctagt tgatccaaac tcaatcccta
    30001 aagatgtacg accatctatg acatctaaca tactttgcgc atttacttcc ttcataatga
    30061 tttaactccc tccttctcgt caaacctgat caaaccgtct ttttagtagc gcttacaatg
    30121 attattgtat acttttgtac gtacatgtca agcggttatt tacaagaata caataaaaaa
    30181 cacttgtttt gtacgtacat aagttataaa atgaaattgc ttacaaaatc tgatcaaccg
    30241 ccttctcgaa attctagaag gagagaatac ttatgaaaaa agaaaaaaaa gtttcctcat
    30301 cgtttattta tttttttggc gcatttggcg gcattctatt tggatatgat attggtgtta
    30361 tgaccggcgc cttacctttt ttacagcatg attggggttt ggcaggtaaa gcttctttga
    30421 taggatggat cacgtcttcg gtcatgttag gtgcgatcct tggcggctct ttatctggtc
    30481 ttctttctga taagcttgga cgacgaaaaa tgattcttct ttctgcactt atttttatgg
    30541 ctggttctgt cctttctgca tctgcccctc acaatggttc ttattttctg attgcagcaa
    30601 ggattcttct aggtttagct gttggcgctg catctgccct agttcctgct tatatgtctg
    30661 aaatggctcc tgctagacta aggggaagat tgtcagggat caatcaagtg atgattgctt
    30721 ctggcatgct cctttcctat gttgcagatt atttgctaaa agtgttgcct gaaacgatgg
    30781 cttggcgcgt gatgttaggg ctcgctgctg tccccgcgct gattttattt ttcggtgttt
    30841 tagctctacc agagtcaccg cgttttctta tgcaatctgg ccgcttggaa gaggcaaaaa
    30901 gagtattgaa ctatattcgg acaccaaaag aagctgaaca ggaattcgaa caaatccagc
    30961 tgaatgtcaa acaagaaaag acaaccggaa cttcttggca tactttgttt ttagaaaaat
    31021 atcgttcctt agtcattgcc ggtattggtg tagcagtatt ccagcaattt caaggagcta
    31081 atgctatttt ttactatatt ccgctgatcg tagaaaaagc gactgggcat gcagcgagcg
    31141 atgcattgat gtggccgatc atccaaggaa tcattttagt tgctggttct ttgctctttt
    31201 tggttattgc agacaagttc aatcggcgaa ctttattgaa aataggcggt agcgtgatgg
    31261 gactttcatt catcctacca gctgttttag gaactgtact ggatgctcat acaaattcgt
    31321 tgttgattct cttgttttta tgtatttatg tcgcatttta ttcttgcaca tgggctccac
    31381 tgacatgggt aatcataggc gaaatattcc cactagctgt ccgcgggcga gcatctggcc
    31441 tagcctcttc ttttaattgg attggttctt tcctagttgg cttgcttttt cctgtgatga
    31501 ctgcttctat gtctcaagaa atcgttttcg gcatttttgg gatcatctgc tttttagggg
    31561 ttttatttat tcaagagatc gtaccagaaa ctcgtgggaa atctttagag gaaatcgaac
    31621 aaagtgcatc taaaaaaact tatcctaaac gtatttctat ccatcattct taaagaggtt
    31681 gtgacagaag tggtcagctt caagaaataa gaaggaaccg cttagtttcc agtcacaagg
    31741 aacaatttca aaaaacagct tctcatgttt gatgaatatt gtgacttgtg accagttggt
    31801 aggagaacac cgtttagtgg agaggtggtg aaagaaacgt tcagccttga gcgatgacaa
    31861 aagctctcac aaacattgcg acgagtaacc gtaggagcaa taagaggcgg taaaaacccg
    31921 tctcttattt ttcgttttct ttcactgttt cccgttcaac tagtacaggt tcatagagaa
    31981 tatttggctg tgcctgtcct ttttcaatcg ttgtgacgat ccaccgtgcg gcatcttgtc
    32041 ccaacttttc ttttggatgc gtcaatgttg tcaatttttt attccctaaa tggcttaaag
    32101 aagaatcgtc tgttcctacg atcgataggt catctggaat atgatagcca ttttctgtca
    32161 acttatctag cattaaacta gctatttgat cgttatagca aatgatgcca tctaaagctt
    32221 gttcttcttt caaccgttgt actgtttttt cagcgattgt ttctcgtgtt tccgtggtga
    32281 aagtaatgat atcttccgtc aaaaaacgca cattatactg ttcacacgcg ctgataaaac
    32341 ctttcatcct gtattttcct tgaagatcgt cgatttttgt gatgaacaac agacgctgat
    32401 gtcctttttt tatcaaatat tctgctgcca taaaaccgac tttcacatca tctaaacaaa
    32461 tataagaggc atttaactct tcataagcag cattgatcat caccatcgga atgccttgtt
    32521 ctctcaaagc aacataaagt gctaagtttg ggttatactg attacttttc gtaggctcaa
    32581 cgatcaaacc atctacccca taagcaatca ttttcttcaa acactctttc tccaattcgt
    32641 gatcgttatt cgtactggct aaaagcaatg aatacccaga ttctcgtaat tcattttcga
    32701 ttcctcggat aatcgacgga aaaatataat cagagagata tgtggtgatg acaccgatcg
    32761 tttttgttct gttcaatggt gttttttctt tcttatagct gtcatctaca tatgtgcccg
    32821 accctttttc tttacgcaga tagccctcat ttaccaacac agcgattgct tgccgaatcg
    32881 tatgtctgct gacgtcatat atttcttgca gcttgaattc tgagggaatg gttgtattta
    32941 cttcgtattc ctcacgaagg atcttttgtt ttatctcttc tgcaatatct tgatattttg
    33001 ccatttgcct tgcccctttt tatttgtacg tacatatatc ataacgagtc tgcaaggttt
    33061 attcaagcaa aaatcaaggt ttcttgtgct cataaggcat acggaacagg ttcaccaaat
    33121 tctggaaatc cttgctcatt ccacgtaaag cattgcgcgt tcgcgtgccg attaggattg
    33181 tctaacggat cccctttttg gttcttctct ggtcgagcat gatagatcaa aatatcaaag
    33241 cacccgtctt ctgaaaccgt aaacgagttg tgaccaggac caaattgctt atttttttca
    33301 gaagaaacga atactggctc cgataattta tgccatgatt cttttaataa aagattcttg
    33361 tgctcatcag cccacagcag gcccatggca tagttttcat ctgttgcact accagaatac
    33421 gtaatgaata ttttcccatt gcgagtaagg actgctggac cttcatttac tgaaaaaccc
    33481 cgtttttccc attcatactc aggtatagaa aggaggatct gcttcccctt taacgtccaa
    33541 ggattatcca tttcggatag ataaagatta gaattcccag taatttcagg atcttgttgg
    33601 gcccacacat aatatagctt tccttgagaa gagaaagttg ttccgtctaa actgaaagtt
    33661 tcccttttcg tttttatttg tcccttttct atccaatctg tattcattgg atctatatgc
    33721 tgattttcaa gtacgaacat gcggtgatga tgagattcat cacgtatagt tttatgattg
    33781 cttgcagcaa agtaaatata ccattttcca ttgatataat ggacttcagg tgcccagatc
    33841 aattcactca tcggtccttc ttcatgagcc tgccatacaa tcaggcttgc agcatgttct
    33901 aattcattca gtgactttgc ccttcttaat tcaatcactt ggtagcctgg aaccgatcct
    33961 gtaaaataat aataaccatc tgtatgttta tatacccaag gatctgcccg ttgccgaacg
    34021 ataggattat tataaagtgt cttcatcata acaaatttcc tcacattttc tttattctaa
    34081 ttacattcca agagtatttt tctatcccta catttaattc gtcatgtttt tctattgaaa
    34141 aatagtttat ttcaggtttt attttttctg gttcttcacg tgtatttttg tccaacagat
    34201 cgctactggt taatgtgtag tgctctcctt gatctagcaa attgaaatca tgttcaatcg
    34261 ttatcttttg ttgttcattt gtgcgattga tcaagaaaat agtcagctga ttgccgttat
    34321 ctacgatcac actgtccaca taaggaacat tttttatctt ttcacaatca taaacagggc
    34381 aaatgatttg ttgtttcaat acttgacctt tagcatattt cgataagtgt tgcatcacat
    34441 aataagttgg attcctccat gcttgtcctt tagcatctgt cagtattaaa ggtattgtgt
    34501 ttactaacaa tgattgacaa ctaatcttta cgcgatctgc gtgtcgtaaa atagccagcc
    34561 ctaatgaacc aaataataat gtatcttcca tagtaaagta acaccaatcg atgggactac
    34621 cgacttcaaa atccctatgt cttttttccg gttgggcatg tacattccat tcatcaaacg
    34681 ctagatacat tgttttctca cttctcaaat atccttttac ataatcacaa gtagcaacga
    34741 tttcttcaat ttgacgatcg aatcgataag cttttgcaag gtatgtcgct gtatcatcac
    34801 gctcattttt aggaggttta gtcaagtctt cttcatcata cttatcaata tagttatgca
    34861 aagctaaata atctacattc tcataagctt cttctaatgc gatacgatcc cattcagggt
    34921 acgatggtaa acgtggcgta gagcttccaa ctaagattgt ttcaattgaa tcatccacta
    34981 acttcatgac ttttgaggct tcatttgcta acctaccata ttcataagca ctcttagccc
    35041 ccacttgcca tggaccgtct agctcattcc ctaaacacca taatttaacg ccaaaaggct
    35101 ttttttgccc attttttatt cttaaatcac tccagaaggt tccttttgga aaattacaat
    35161 attctactaa attttttgct tcatcaattc cttttgttcc taaattcacc gtgaatatcg
    35221 gtttcgcttg tacatgactg atccatttaa aaaattcgtg gagtccaaaa gaatttggtt
    35281 ctatacctcg ccatgctaaa tcaatttttt ttggtcgttg ttctttccta cctacagtat
    35341 ccacccaatc ataaccagat gtaaagtttc ctccaggata gcgaatgaca cctaattcta
    35401 attcctttac ataagagagg acatcttgtc taaacccgtc accatcagct gtttcatggc
    35461 ccggttcata aatccctgta tagacgacac ttcccatatg ctcaacaaat gagccaaaca
    35521 gccgagaact gatctctcct accgtaaaat cctctctgat ttttactttc acttcttcgt
    35581 ccaacagctt tccctacctt tcatttccta tagtcaagat aatagataca agtttccata
    35641 cgccaccagc aaagataaaa ataaaaggag ggaaaagaaa tatgagcagt acaaatccta
    35701 ataacaatac gcaacaaaga atatttctca aaaaatcaaa aaatactttc catgcacttt
    35761 gttcaaaaat ttgtaaaaat gtgatatctt tgttttcaga aatcacatat atccaggata
    35821 aaagaaacat ggaataaata agtaaaacta catatccact aattgaaagt acgattgtct
    35881 gttcttctaa taattgatta acaagaaaat aaataatgat cgttaacaga ctaaggaaca
    35941 agttcttacc aaaatgttgc tttattcctt gaaagaaaaa ataaatgata tttcctgatc
    36001 cctcaccttt ccattgcgcc attacataaa aaacagcaca tgtagcaggc acgatagtaa
    36061 taacaggcaa acacacgatt acccagagaa tacctaataa gatgtaatca gaaaccacaa
    36121 tcaactgtcc ataaaattta gtctcaacta ttttcatctt cctcactctt tcattccaga
    36181 catagctgtt ccttgaacaa aatatttctg tgcaaaaata taaaccacta gtaatggcag
    36241 cattgaaata accgttccag ccattacagg tccataaaaa gaaatgttct gccctgtaaa
    36301 taaagctaac cctgctggta aagttctcat ttttgaacta cttgtcaata tcaatggata
    36361 aagcaagtca ttccaactat tcatcagcgt gaaaatccct aatgataaaa gagtaggttt
    36421 gctcaatggc aacatgattt tcaaaaaaat attaaactca cttaatccat caatgcgtgc
    36481 tgcctcttcc aaagaatctg gtaaagtaat aaaaaaggaa cgcatcatga agataccaaa
    36541 tgcagttgtc atacgaggaa tgatcaaacc tgcataagta tcaagcatgc caagcaaatt
    36601 gacttcaata aatagaggaa tcatgaagac ttggaatggg atcatcattg tcagcaaaac
    36661 gaaatagaac aaaactgatt ttcctttgaa acgcatacga gcaaatgcat accccgcaag
    36721 agaatcaaag aatacagaag tgatcactgt ccctccagca aaaatcactg tatttttgat
    36781 gtaatctaat aaagggatcg ttgtccaaac cttaatatag ttatctaggg tatagctatc
    36841 tgcaaatatt ctaggcggaa atgagataat gtctttttcg tgtttaaaag aagaaataat
    36901 cagccacaaa aaaggaaacg caataaccaa caatataact agcatactaa tcgttcgaat
    36961 gattttttta ccactaactg cttttcgact attcacagta actgtaatcg agctttctgg
    37021 tgccatacag gtttccctcc tatttcattt gtttttcttt ccgtgacatg tacacattag
    37081 tggagatagc tatagttgca acaatgataa acaaaaccga agacagtgct gatgcatagc
    37141 ccaattcata aggtgctgta aatcctcgac tgtaaatata ttgaacagct gtttctgtct
    37201 taaattgtgg gccaccagcg gttgcaacat atacttggtc aaacacttgc atcgaaccaa
    37261 tcagattcgt taaaatacaa aaacctaagg agggaacgat ctgaggtagc gtaatgttaa
    37321 aaaactgctg tcgatttgtt gcaccatcca tttgagcaga ttcatacaaa gagggagaga
    37381 ttccctgaat agcagtcaag agaatcgtca tagtaacacc aaaattcttc caaacagtca
    37441 tgatggctac cgtcggcata gcaagggttg gatcgcgaaa aaattgaggg atcggcaagc
    37501 cgacttgtga aaacaagtaa ggaatcgccc ctacattcgg atcaagcaac atagaaaaaa
    37561 taatcgcaat tgacgtcaat gaacaaataa ctggaatgta aaatgtcgaa cgacaaaaac
    37621 gattgaatct ggtattttta gataatgcta ctgctgctaa taaaccaacg ataatttgtg
    37681 ttggcgtttc gagtacggtg aaatataaag aatgaatcaa cgaattaact gctcgttcat
    37741 cactaaatat acgtgtgaaa ttttcaaaac ttacaaaatt tcttgatgta aagaaaatat
    37801 tcaaatctgt aaaactaata gcaaatgttc ctaaaagcgg tatgacagta aataataata
    37861 aaactaaaaa agatggagtt aaaaacaaat acgcagcacg atcaggacga ttccaatatt
    37921 tggtgaatcc gttcatatag tccacctcat ctttcatttt gataaaatat acaatcttgg
    37981 tttaaacgaa tctgaataag atatccgaac aatcgctgtg atttttgcaa taacacctat
    38041 ctgcaaatac taggtcgatc attcagatat ctgtatcttg ccaacagtct atcctgtata
    38101 aagttctgta ctatttttgc agtaattgat tgatggcatc atctgcatcg ttcatgagtg
    38161 tctcaggatc ttctcctgct aataattttt caatcagtgg attgatgata tcgttattga
    38221 tcgcagagat ttgggtaaaa cctggtaaat atggctctgc atagtccatt tgtttcgata
    38281 attcagatac aataggatca ttttttactt cttcatcttt tgctactgaa tccaagtagg
    38341 caggaaaacc attttcgata ctccattttt taccaatttc agttgtattc caatatttca
    38401 aaaactcata gacagcttct tttttattat tatctgtact tgccggaatg gcatatccta
    38461 cgccatctaa aatagctgtt tttttgtctg aatcactccc ttgtggtaag gtagtcacat
    38521 tataatcaat ctcgtttgct ttcaatccgt tatttaacca tggcccattg atttcaatgg
    38581 ctagttgacc agcattcatt aaattgtcca tttcggcgcc agaaatcgat tctggaccag
    38641 tcttgtctac atggatcatt ttttggatcg cttttaacgt tttaaggttc tcaggagacg
    38701 caaattcaga cttagtataa tcatcgttca ctaatttacc gccatttgct aacatccagt
    38761 tatataacgg tgcagttcca tccttattga agacaaaacc tgatacattt ttactactat
    38821 cagttaattt tggtgccatt tctgtcaatt cttcccaagt agtaggtggt tgttcagtat
    38881 ctaatccagc ttgtttaaac aaatcattat tccaatacat atacatgcct tgtacctgca
    38941 tggggacaaa atactgttta ccttctactt cacctaattc aatagccgtt tctttaaaat
    39001 cagatttatc tactccatca tattcccaga aatcgtctaa tggttgtacc gctccgtttt
    39061 ctacatactg tgcaaaatct ggataattta atgcaataaa gtcaggtgct tttttagaag
    39121 aaatcgctgt aggaagtttt tcattcaaat tggcccaagt catgatatcc atttcaattt
    39181 tgatgttttt atcatttgtt ttattaaatt cattaacgat ttcttgcaat atttcaccat
    39241 cagatgcagt aaacccattc caaaaagtca aagtcacttc tttatcagaa tcagattctg
    39301 ctgaacttcc gccaccgcaa gctcctaaaa tacctgttgc agctaccaac aaagagccaa
    39361 ttaaccattt tttacctttc attttttgtt cctccttcat ctgataaacg acatctgacc
    39421 acattccaag atagcggttt caataaacaa ttgattttcc catcttcagc ttttacattt
    39481 gttgaatgac ttggttttac ttgttcactt ttaggaagat tagttgcttt tgtatcaaat
    39541 ccactcattt cagaaaaatc aatcactccc tctaatgata attcagacaa gtgaacagtt
    39601 agattcattt cttcttctcc acggttaact gcaaatatga caagttcttt gtcatttatt
    39661 acggctatac tttctaaata cggcacttct tcaaaatctt ccgtcgcata gtttgctgaa
    39721 cgaatttgtg ggcttaacac ctctccttgt ccatacacag cagcttgcat aaatggataa
    39781 tagatcgtct gtctccaagc ttctccgttt gtttctgtcc tgattggtgc aataacattt
    39841 accaattgag caagacaagc aatctttact ctatctgcat gtttcaataa agtgattaat
    39901 agacagccta atagtaatgc atcttcaaaa ttatagttat cttctagtaa aggaggagca
    39961 atctgccaag gcgctgcttg ctcatcttgt tccgctgaat gataccaaat attccattca
    40021 tcaaaggaca ggttgatctg cttcttacta tgtttcttcg ccttgactgt atcgcacatc
    40081 gctgtcactt cagaaatgaa ccgatccatg tctaaggaac gtgcaagata atgagaaaga
    40141 tcattttttt ggttgccata atattgatgc agagacaaat aatctatttg atcgtacgct
    40201 tgatcaagaa ctgttaactc ccaatcacca aatgtaggca tttgccgatt cgaacttccg
    40261 cataaaacca cctcaattga atcatctacg agtttcatcg ccttagccgt ttcctctgct
    40321 aaccgtccat attcttccgc tgttttatgt ccaatctgcc aaggaccgtc catttcattc
    40381 cctaaacacc atgtcttaat tccaaaaggg ctctcttgac cattcgaacg ccttaaatca
    40441 ctccaataag ttcctttagg aaaattacaa tattcgacta aattacgagc tgcatctact
    40501 ccacgagtac ccagattgac agccatattg atttcggccc ccacatgctg acaccagtta
    40561 taaaattcat gaatcccaac ttcattcgtt tcaattgtcc gccaagctaa atccaacctt
    40621 ctaggtctat ttgctatggg cccaatactg tcttcccaac gaaatcctga cacaaaattt
    40681 ccaccaggat atctaatcat gggaatgttc aattctttta ccaagtgaat gacgtcttgg
    40741 cgaaatccac ttttattagc tgatggatga tctggctgat aaatcccttc atatactgct
    40801 cgtcccatat gttcaataaa tgaactgtac aaccgcggat caactttgcc tacacgcttg
    40861 acactactaa tcaacattgt ggcttccata actgacctcc tttaatttat acatgaataa
    40921 tacacctcgt tgaaagcgtt gtcaataata taaatgttaa acttacttat tttttatcga
    40981 ttttaattaa ccaaaatatt aataatgatt aaaacaaata atttaatata acttttatta
    41041 acaaatatgt taatatataa gaaaaacctt ttaagaggtg atatatatgc aactacaaat
    41101 aaacgaagaa tccttaccgg tatatgaagc attagctagt aaaacaagga tcaagatcat
    41161 ccagctactt tccaaaaaaa agatgaatgt caaagatttg gcaaaagaac ttggagtgag
    41221 cagtgctatc acgacgatgc acgtgaaaaa gctagaggaa gcaaacatca tcaaaacaga
    41281 aaaagtagga caacaaaaaa tttcgagcct tcgtgtcgat aaaatcgata tcagttttcc
    41341 agaaaaaata ttcaatgctt ttgatacgaa agaaacatcg atacctattg gtcactatac
    41401 aaattatgca attgaaccaa catgcggttt agctacgatc catgatttta tcgggaaagt
    41461 ggatgaacca cgctatttta tggatcctcg aaggatggat gcccgcattc tctggtttac
    41521 cagcggattt gtcgagtatc aggcacctaa ttttttaaat acagaggata cattggagat
    41581 gttggaagtt tctgtggaaa tttcttctga atttcctttt tcaaatgaca attggccttc
    41641 agatatcact ttcagcctaa atggtgtgga gctaggaaca tggacgagcc ctggagattt
    41701 tgctgatatc cgcggtaaat atacgcctga ttggtatcca gataatctta atcaatacgg
    41761 cttgctgaag acgatccgaa ttaccaaaca cttgacgaat atgaatggag aacccttgtc
    41821 aaacatcacg atcaacgaca tccctaaaga gcaagacact tggcatttgc gaatcgaagt
    41881 gaaagacgat gccaaacatg tggggggctg tactttattt ggtaaaggat tcggtaatta
    41941 cgatcaggat atcaaattaa aagtttacta cagctgatat ttttcttttc tattttataa
    42001 aacaaaaaca gccaatccct atgaagggac ggctgttttt gctttattgt tatttccaga
    42061 aatcatccaa aacggaaatt ggcaaatgtc gtttatgttg tgtcttgttc caccatgctt
    42121 cgattttttc ttgtgcttga gcgggaactt cttttccttc tagataatca tcaatttcat
    42181 tatatgtgac acctagtgcg acttcatctg caatcattgg tttcccatct tcaagatctg
    42241 cagtcggaat ttttgtgtat aatttttccg gtgcattcaa tgcttgaagc aattgtttcc
    42301 cttgtcgttt gtccaaacgg aataatggca aaatgtcggc tccaccatca ccaaatttcg
    42361 tgaagaatcc agtaatgttt tctgcagcat gatctgtccc taatacggct cctgctcttt
    42421 ctccagctac ggcatattgc gtaatcatac gttgacgtgc tttgatattt cctttgttaa
    42481 aatcgctgat tcccacacct gcttcgctta atacttgtac ttgtgcatca acagctggtt
    42541 tgatatttac tcgcagacta acatcgggct ggataaagtc aagagcagct tttgcatctt
    42601 cttcatctgc ttgttcacca taaggaagac gaacagcgat aaattgatag ttttcatctt
    42661 ttgtttcttc acgcatttct tccatcgtta gttgcgccaa acggcctgct aaagtagaat
    42721 cttggccgcc gctgatacct agtacaaaag ttttaagaaa cggatatttt ttcaaatatg
    42781 ctttcataaa gtcaatactt ttacgtattt cttcttttgg atcaattgtt ggtttgacac
    42841 ctaattcatt gataatttct gtctgcaggc tcatttattc tcctcctatg cttctgtatg
    42901 aagttctgct acgctttttt tcattcgttc catgatagcc attttatggt tccagcattc
    42961 agtagacaga tcgactgggt atttttgcgg attcaagtct cgtttatact cttcccatag
    43021 tgaatctaga ttttcttttg tatattcttt gatttcgttt agtgcaggta attcgtaaac
    43081 tctttttcct tcgataaaga tatcttgtaa aactgggcga gctgtaaagt ctcgaacagt
    43141 tttattgata aacgtatgca ctggatggaa catgaagata gcttcttctt ctcgagggtc
    43201 ttcatcccat aatgtcacgt agtctccttc agatttccca tcaaaatttc gagtgatgcg
    43261 ccacacttgt tttttccctg gagtagttac tttttctgca ttgcttgata acttgatcgt
    43321 atccatcatt tttccttcat catcttcgat cgatactagc ttgaatactg caccaagggc
    43381 tggctgatca taggctgtga tcaattttgt cccaacaccc catacatcaa ttttagcttt
    43441 ttgcatcttt aaattcaaaa tcgttgcttc atccaagtca ttcgaagcat agatttttgc
    43501 ttccgtaaat ccggctgcat ctaattgttc ccgaacacgc ttagatatat aggccatatc
    43561 tccactgtcg atgcgtacgc cttggaagtt gattttgtca cctaattctt tcgccacgcg
    43621 aatcgcactt ggcacacctg atttcaacgt atcataagtg tcgactaaga acacgcagtc
    43681 tttatgggtt ttagcgtagg ccataaatgc ttcataatca tttccataag attggactaa
    43741 cgaatgagca tgggtcccgc tagctggtat cccaaatatc ttcccagcac gtacattgct
    43801 tgttgcatct gctccgccga tatatgccgc tctagttccc cagactgctg catccagttc
    43861 ttgtgcccgt ctagttccaa attccaatag tggatcttct ccgatgacag atttgatacg
    43921 agctgctttt gtcgcgatca acgtttggaa attgaccata ttcaacagtg ctgtttctac
    43981 taattggcag tgcgctaaag gcccttccac ttggattaat ggttcatttg caaaaactag
    44041 ttctccttca cgagcagaac gaactgttgc tttaaattca aaattttgta aatactccaa
    44101 aaaaccttca ggatagactt ctaatccacg caagtaagca atatcggaat cattgaacgt
    44161 cagattctct aaataattga ctaaccgttc caatcctgca aaaaccgcgt atccgtggtt
    44221 aaaaggcatt tctcgaaagt aacattcaaa aacagcatgt aaatcagctc gacctaattc
    44281 ccagtatgtc tgcatcatat tgatttgata tagatccgta tgcagcgtca aactgtcgtc
    44341 tgggtaagta ttattcatct tgtattactc ctcttggcaa gttttcattt cctacccatt
    44401 ataacaaaaa aaattaatag gaaaagaaat cttccatttt ttctgaaaaa gcacatgttt
    44461 tacggatatt tcttgctaaa aatgaactcc atctgctaaa actatccttt cttattggta
    44521 tttaacctaa acgagaaaga atacttattt tattcaatgt atccgagaca cgaagaaatt
    44581 agcgttttct atttttctta cttgataaaa taagtagatt ttcctactac aatcgtagcc
    44641 gttaagatac cgatgattga acaaatataa ccaaatgtct ctacaacata atcaatggca
    44701 aaagtttttg aagcaataat acgtctttcc ttttttgctt cttatcccca aagaaacgga
    44761 tataacttat tatgtattga atttttttgg aaaggcgaat tatgacaaga tataccttgc
    44821 gttgaaaaaa ctcgcggaaa aaatatcaca cgtttttaaa aagatacaaa gtaagaaagc
    44881 agctgtcaat agaatggaaa caaaaatggc gagacatcaa tcagtctcgc cttgtttttt
    44941 attgtataca ttagatatgg agcaggttac cataaagatg attattagtc gttattaaat
    45001 agaatccttc gtattttttt gttctatcac tacaatatct ttatttggac gtttgaattg
    45061 tattccggca cgttctagct cctgtttcac tcctacatgg actttgacat cttctcgtgt
    45121 catttttaaa acgtgatgaa tcgcatagtc gatttcttgc cttgtgattt ttttcttcgt
    45181 attgatcatc acgacttgct ttttatcata tgtgtctacc aatagcagtt gtgttcgatc
    45241 taacgaaaat aatttgtaat aattaatagc cgtattccca aaaaagaatt ccactacttt
    45301 aggataaaat gtcttaatat ttaaattact attcacaggt gtttcgatta gcttcatctc
    45361 attcctcttt tctatatagt cgatttagat ccaatcttaa gttatgttac catctttcct
    45421 agcattaagg aatcggttac aattgaacct ttaaagacaa aaggatttac cttttatcac
    45481 ttaatagtat aacataattt cgtgagaaaa aaatacaatt ttttcttgac catctcgtta
    45541 cgtaaaggat tatgcttaca tttgtcagga ggaaaaataa tggagtacac aataaagaaa
    45601 atgtcagaga tatcaggagt cagtccgaga accttgcgct tttatgatga gattggactg
    45661 ctaaaaccag ctaggatcaa ttcttcaggt tatcggattt atggcaaaaa agaagtcgat
    45721 cgtctgcaac acatcttatt ttatcgaaca atggcattca agttggatga tatccaagag
    45781 gtcttagaca atccatcttt tgaccaccag aaagctttaa tcaagcatca gcaaatgttg
    45841 ctggaaaaac gggcacaaat cgataccctc ttgacaactg tccaacagac acttgatatg
    45901 tacgaaggag gaagaaaaat gagtgacaaa gaaaaatttg aagggtttaa acaacaaaag
    45961 ttgaaagaaa atgaagaatc ctatggacaa gagattcgac aaaaatacgg aaaaaaaaag
    46021 gttacagcat ccaatgaaaa atggatgaat atggataaag aaacgtatga agaaatgcaa
    46081 actgttgaaa agcagatgtt atttgatctc actctttact taaaagaacc agaagatgaa
    46141 agcttagcag accgtatctt ccaagctcat aagaagtggt tctcttacag ctggcctgaa
    46201 tatcagccaa aagcgcataa aggactagga atgatgtacg aagccgatga acggttcact
    46261 gcatattatg acgagcgaag tggtcatggt gcagcaaaag ctttaaatga aattatccaa
    46321 aaaaaggcgt aatcttttac atgatccaac aaaaaagtac acgtaaaatg acctaataac
    46381 aaaacagcag acacccaagt tagattttta tgctaacttt tggtgtctgc tccattcttt
    46441 cacaagtttt ttcatcctac tttaaatata ttcatcgttg aataaacgta taaggtattt
    46501 tcactttatc ctttttttct gtaagaaaca attgaaatgc catttctccg caagcttcca
    46561 gatggtggtc gatggttggg aaaccaagaa gctcgctgat cagcaaatta tcgcgtccaa
    46621 tcaccactgg tgtcttatct tgcagatagc tttgcaagat gcctgctgca accatatccg
    46681 aatttgtaaa gacaccatca actccaagct ctttaaaaaa gaagcctgct tgttttcctt
    46741 tctctgcatc tatacaatcc caaaaaacaa gtgattcatc aaaagatgga aaaagttgat
    46801 gacatagctg caaagtgatt tttgagttat aacttagcct gccacttcgc cccaacgtga
    46861 tgcccaattg ctttatacct tgctgcttca aataagtaag accttctgta attgattgtt
    46921 ctcgatcaat aaagacacag cttgcctgtt ttcccttgat ttcttcacaa aaaactagag
    46981 gtccatattt ttgatatgcc aataaatcat ctagtgtatt ggcacgagac gtaatgatca
    47041 atccatcgaa agctttagct gcaaattctt caagatacct tcgctctttt tctttatgat
    47101 agcccgtcgg taaaagtgtc actttgtaat cataatcaaa cgctgcttca atgatcccac
    47161 tgatcaactg atcaaaatac ggatgattgg tataaggcag aatcactcca atgcttttcg
    47221 tttttccata acttaactgt ctggcatttg cattagggat ataatcgact tctttcatga
    47281 ccgcaagtat ttctttcctt ttttcctcat ctacatatgg atgtccattg attacacgtg
    47341 aaatagtaga aactgaataa cctgtgagct ttgcgatatc tcgaatgttt gccactgctg
    47401 cttcgccacc tatacaaaaa gattttcttg taaatagtct accacagctg gaccgcattc
    47461 aaaaaactga tacatttttc cttcatgcga aaaactgatc cgctgcccgc cccaatatat
    47521 atcttttgtc aaattttcga tttcattcat tggtatttct tttactatat tcctattcaa
    47581 cccttgaaaa ctgtacaacg ttaatacgga tcccttgaac tcgacaaacg cataaaaata
    47641 attgttcgtt gtgccatctg ttatctctac ataagtattc attgcaagcc ctccttttga
    47701 tactttgagt atagtgtatg aaacgcgtct catagcaagg agtttgtttt gccaaagaaa
    47761 agttttattc ctctttcatt attaccaaag tctcttattt taaattgaat acattataat
    47821 gatactgtaa atatatcttt attattagtg aatg
//
LOCUS       DAFEKH010000021        44491 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.022, whole genome shotgun sequence.
ACCESSION   DAFEKH010000021
VERSION     DAFEKH010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44491
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.022"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(45..1511)
                     /locus_tag="LP386_001260"
     CDS             complement(45..1511)
                     /locus_tag="LP386_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBL1918507.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
     gene            1898..2494
                     /locus_tag="LP386_001261"
     CDS             1898..2494
                     /locus_tag="LP386_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBL1918508.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
     gene            complement(2552..3034)
                     /locus_tag="LP386_001262"
     CDS             complement(2552..3034)
                     /locus_tag="LP386_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918509.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(3140..3337)
                     /locus_tag="LP386_001263"
     CDS             complement(3140..3337)
                     /locus_tag="LP386_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918510.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            3632..4390
                     /locus_tag="LP386_001264"
     CDS             3632..4390
                     /locus_tag="LP386_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HBL1918511.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            4450..4878
                     /locus_tag="LP386_001265"
     CDS             4450..4878
                     /locus_tag="LP386_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918512.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            4924..4996
                     /locus_tag="LP386_001266"
     tRNA            4924..4996
                     /locus_tag="LP386_001266"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4957..4959,aa:Gln,seq:ctg)
     gene            complement(5146..5517)
                     /locus_tag="LP386_001267"
     CDS             complement(5146..5517)
                     /locus_tag="LP386_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBL1918513.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            5732..5917
                     /locus_tag="LP386_001268"
     CDS             5732..5917
                     /locus_tag="LP386_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918514.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(6000..6188)
                     /locus_tag="LP386_001269"
     CDS             complement(6000..6188)
                     /locus_tag="LP386_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918515.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(6212..6475)
                     /locus_tag="LP386_001270"
     CDS             complement(6212..6475)
                     /locus_tag="LP386_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918516.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            6633..6890
                     /locus_tag="LP386_001271"
     CDS             6633..6890
                     /locus_tag="LP386_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HBL1918517.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(6961..7152)
                     /locus_tag="LP386_001272"
     CDS             complement(6961..7152)
                     /locus_tag="LP386_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918518.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(7293..7615)
                     /locus_tag="LP386_001273"
                     /pseudo
     CDS             complement(7293..7615)
                     /locus_tag="LP386_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7638..8072)
                     /locus_tag="LP386_001274"
     CDS             complement(7638..8072)
                     /locus_tag="LP386_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBL1918519.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            8407..9045
                     /locus_tag="LP386_001275"
     CDS             8407..9045
                     /locus_tag="LP386_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL1918520.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPV
                     QAEQPVVQETVQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTAT
                     NGRYIGRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(9369..9452)
                     /locus_tag="LP386_001276"
     tRNA            complement(9369..9452)
                     /locus_tag="LP386_001276"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9416..9418),aa:Leu,seq:cag)
     gene            9980..10480
                     /locus_tag="LP386_001277"
     CDS             9980..10480
                     /locus_tag="LP386_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1918521.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            complement(10670..11014)
                     /locus_tag="LP386_001278"
     CDS             complement(10670..11014)
                     /locus_tag="LP386_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HBL1918522.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(11168..12088)
                     /locus_tag="LP386_001279"
     CDS             complement(11168..12088)
                     /locus_tag="LP386_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL1918523.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            12275..12766
                     /locus_tag="LP386_001280"
     CDS             12275..12766
                     /locus_tag="LP386_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HBL1918524.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            complement(12790..15165)
                     /locus_tag="LP386_001281"
     CDS             complement(12790..15165)
                     /locus_tag="LP386_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HBL1918525.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            15491..16117
                     /locus_tag="LP386_001282"
     CDS             15491..16117
                     /locus_tag="LP386_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBL1918526.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            16140..16844
                     /locus_tag="LP386_001283"
     CDS             16140..16844
                     /locus_tag="LP386_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBL1918527.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            17036..17869
                     /locus_tag="LP386_001284"
     CDS             17036..17869
                     /locus_tag="LP386_001284"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBL1918528.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            18066..19994
                     /locus_tag="LP386_001285"
     CDS             18066..19994
                     /locus_tag="LP386_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBL1918529.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            20132..20587
                     /locus_tag="LP386_001286"
     CDS             20132..20587
                     /locus_tag="LP386_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HBL1918530.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            21057..21326
                     /locus_tag="LP386_001287"
     CDS             21057..21326
                     /locus_tag="LP386_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918531.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            21726..21980
                     /locus_tag="LP386_001288"
     CDS             21726..21980
                     /locus_tag="LP386_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HBL1918532.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(22069..23115)
                     /gene="holA"
                     /locus_tag="LP386_001289"
     CDS             complement(22069..23115)
                     /gene="holA"
                     /locus_tag="LP386_001289"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HBL1918533.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(23153..25426)
                     /locus_tag="LP386_001290"
     CDS             complement(23153..25426)
                     /locus_tag="LP386_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HBL1918534.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            complement(25419..25958)
                     /locus_tag="LP386_001291"
     CDS             complement(25419..25958)
                     /locus_tag="LP386_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HBL1918535.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            complement(26094..26312)
                     /locus_tag="LP386_001292"
     CDS             complement(26094..26312)
                     /locus_tag="LP386_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HBL1918536.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            complement(26309..26554)
                     /locus_tag="LP386_001293"
     CDS             complement(26309..26554)
                     /locus_tag="LP386_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBL1918537.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            complement(26670..27398)
                     /locus_tag="LP386_001294"
     CDS             complement(26670..27398)
                     /locus_tag="LP386_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HBL1918538.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            complement(27557..28600)
                     /locus_tag="LP386_001295"
     CDS             complement(27557..28600)
                     /locus_tag="LP386_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HBL1918539.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            complement(28590..29081)
                     /gene="coaD"
                     /locus_tag="LP386_001296"
     CDS             complement(28590..29081)
                     /gene="coaD"
                     /locus_tag="LP386_001296"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HBL1918540.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            complement(29078..29638)
                     /gene="rsmD"
                     /locus_tag="LP386_001297"
     CDS             complement(29078..29638)
                     /gene="rsmD"
                     /locus_tag="LP386_001297"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HBL1918541.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            complement(29757..30095)
                     /locus_tag="LP386_001298"
     CDS             complement(29757..30095)
                     /locus_tag="LP386_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HBL1918542.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            complement(30079..30516)
                     /locus_tag="LP386_001299"
     CDS             complement(30079..30516)
                     /locus_tag="LP386_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBL1918543.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            complement(30506..31630)
                     /locus_tag="LP386_001300"
     CDS             complement(30506..31630)
                     /locus_tag="LP386_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918544.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            complement(31651..35079)
                     /locus_tag="LP386_001301"
     CDS             complement(31651..35079)
                     /locus_tag="LP386_001301"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HBL1918545.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            complement(35105..36268)
                     /locus_tag="LP386_001302"
     CDS             complement(35105..36268)
                     /locus_tag="LP386_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBL1918546.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            complement(36271..36573)
                     /locus_tag="LP386_001303"
     CDS             complement(36271..36573)
                     /locus_tag="LP386_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HBL1918547.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            complement(36687..38459)
                     /gene="recQ"
                     /locus_tag="LP386_001304"
     CDS             complement(36687..38459)
                     /gene="recQ"
                     /locus_tag="LP386_001304"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HBL1918548.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            complement(38720..40549)
                     /gene="typA"
                     /locus_tag="LP386_001305"
     CDS             complement(38720..40549)
                     /gene="typA"
                     /locus_tag="LP386_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HBL1918549.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            complement(40717..41484)
                     /locus_tag="LP386_001306"
     CDS             complement(40717..41484)
                     /locus_tag="LP386_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HBL1918550.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            complement(41490..41764)
                     /locus_tag="LP386_001307"
                     /pseudo
     CDS             complement(41490..41764)
                     /locus_tag="LP386_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
     gene            complement(41926..43332)
                     /gene="lpdA"
                     /locus_tag="LP386_001308"
     CDS             complement(41926..43332)
                     /gene="lpdA"
                     /locus_tag="LP386_001308"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBL1918551.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            complement(43340..>44491)
                     /locus_tag="LP386_001309"
     CDS             complement(43340..>44491)
                     /locus_tag="LP386_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HBL1918552.1"
                     /translation="PSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSA
                     EAPKEKVETSGSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKED
                     IENFLAGGPSSAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPT
                     RKAIAKAMVNSKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALT
                     ATVKKYPVLNASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEI
                     NEKAKLAHDGKLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIV
                     NAEGEIVVGRVMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
BASE COUNT        13073 a         9104 c         7625 g        14689 t
ORIGIN      
        1 aggaactgct gcaaataagc aattcctgtt tttatgttca ttgattaatg aatagagccc
       61 attagttttt tgattggttc tttcacagta aatagcaaga taccaccgac gattgctact
      121 gcaccgataa taccgaagta agcagattct gttcccggtg tgtagaagcg tgcaatttgt
      181 gcattgattg cttgtgaaga agcatcagct aagaaccaaa tagcgattgt ttgtgattca
      241 aatgctcgtg gtgctaattt tgttgtcaca gacaaaccaa ctggtgaaag acacaattca
      301 gcaataacca cgatgaagaa acttcccaac aaccacaatg gacttacttt tccacttgta
      361 ccataaagca tacccggcaa catcaatagc aagtacgata atcctgcaaa taaaagtcca
      421 agagagaatt tcactactgt agatggttga cgttcaccaa gtttcgtcca catcgttacg
      481 aatactggtg tcagaataaa gatgaaaatt ggattcaatg attgatacca gcttgcttgg
      541 atcgttacac caaatagcgt agattgtgta cgttcactag caaataaagc taagatagat
      601 gaaccttgtt cttgtaatga ccagaaaatg attgctgcaa ggaataatgg gatataagcc
      661 catactcttg gtttttcttc agcagttaca tcttttgaag tcagcatttt gataaagtaa
      721 tacaacggta agataatccc caatacactg attgtattga caaaaaagtc aattgtcaga
      781 tgaccagtta gttgtgcccc gccgaatact gcagcgataa caacaagtgc gatgatcaag
      841 ttacggatga atcctttacg ttcttcagtt gtcaaaggat tcggcggtgt tgtacccact
      901 ccgtctaatg tcttgcgtcc ttggatgatg tattgtaata atccaaagaa catcccaata
      961 gcagctaaag agaaccctaa atgatagtta tattcttgac cgattgtacc aacgattagt
     1021 ggtgctaata atgcccctaa gttgacaccc atgtaaaaaa tcgaaaatcc tgcatctctt
     1081 cgcaagtcag tctttgaata aagatgtccg accatgccag aaacatttgg tttcaaaaag
     1141 gcggttccga taataatcaa tgccatcgaa acaaacaatg tacttacacc aaatggtaaa
     1201 gccaagacga tgtggccaag cataatgaaa actccaccga agaatacagt gcgttttgct
     1261 cctaacactc ggtcagatac ccatccgccg acgatactag acatgtagat caaagatccg
     1321 tagatcgaca tgatagctaa tgctgttgct cgtggtaatc caagtccccc gttggcaact
     1381 gtatcgtaca tataatagat aagtaatgca cgcataccgt aataactaaa tcgttcccac
     1441 atctcagtga agaacaaagt tgacaatccc ttcggctgcc cgaagaagcc cttgtcttgc
     1501 tgtttttcca taatctatac cccaattctt taaattttca gaaaatatta tacatcttta
     1561 ccgaaaaatt taactaaaaa acttatttaa gaaatataaa ctaattttct ataaaagcaa
     1621 gtaattttta atggcaatat cataaaaaaa agaagataga gatttaataa ttatatatca
     1681 gctgtttttt tcaaataagc aaaaattcct aaaacacaac aatgaaagcg ataactaaga
     1741 aaatccttac ataacgattt ttcttattaa aattgttttt tgaacttcgc ttattttttg
     1801 tgagcatatc tgtttactta ctttttgtaa ggtgctatac ttcatttcgt aatcaattaa
     1861 aaaaatgcaa aacgcaaatc aaaggagaaa ttttattatg acaactttta ctgacacttt
     1921 gaaaaaccgc cgttcaatct atcatctagg acgtaatgtt tcactttcta atgaagaatt
     1981 aacaactttg atcaaagaag caattaaaga aagcccaact gctttcaatg ctcaatcaac
     2041 acgcgcagtt atccttttcg gagatgcaca tgaaaaactt tgggaaatca ctgaagaagc
     2101 acttcgccca ttgactccag cagaagcttt cccaaataca caaaacaaat tagctggttt
     2161 caaaaatggt tatggtacag tattattctt caaagatact gacgtggtaa aaggtctaca
     2221 agaacaattt gaattatatg cagacaactt cccagattgg tcagaacaat caaacggaat
     2281 cgcaacagct aatacttggg tagcattagt tgataaagga ttgggcgcaa acttgcaaca
     2341 ttacaaccca gttattgacg aagcagttgc aaaagaatgg aatatccctt caaactggaa
     2401 actacgttcg caattagtat tcggttcacc agaaacaccg gctggggaaa aagaatacat
     2461 gaacgatgcc gatcgcttcc gcgtatttgg ataattttat ttgaaataaa aaacagaggt
     2521 tgtgacaaac atcttgtcgc aacctctgtt tttattctgg atcaatcata atatcaatct
     2581 ctgcctcatc gtttaagcgt tgggacaaaa atggaactaa ttcttctaat gatgcagaaa
     2641 atttcagcat cggtcctcgc catccgtttc ggaaaaaatt catttttacg attttagaac
     2701 cttttggctg atataataca attttattga tctcagaaaa aggaacacct tttttgtcaa
     2761 agctattcaa aacaagtcct tcttctgtga ttcctctact gtccaacaaa aaactaataa
     2821 aaatcattgc tgacaagatc ccttttgcca attcatctgc tgtaggatga ctgatgagtg
     2881 tataccaaat gactagtgac actaagaagg gtatcaccaa gtagacccat cgatttcgca
     2941 cagtccgata aataatttct tttcgaacca gccaaagaaa taaaaacatc acaacaacga
     3001 ataaaaacaa tagaaccgta aagaatgtta ccatgacaac tcgcctcgct ttttcttctc
     3061 cagaaaatag gaaaagaata ctgatttacc ttctcaaaga aattggactt gcagcacgcc
     3121 gcacgtccaa ttgttttctt tattcaaatg tatcatattt tgcaacaacc atgcttgctt
     3181 tttcatctaa taattcttgg tcctctgcag cacattgggc aactttgacc acggcgcagt
     3241 ttgtcatttt tgatacaact tcaccaatga ccgtttttgt aaaaccaatt ggtttgcatg
     3301 catattgttc tcctaaatta atcatttctt ccgtcatcaa aatcctccta aactgctgga
     3361 acttttctcc acattaccac tgctatttct ttggagattt aactcattga tttttattta
     3421 cagttaaaaa tcaaccttac aggcattata gcgtactgtt ttcgttttca caattaaaac
     3481 agctgttgta tttagaagaa tttttttcaa aaaattaaaa catattcctt aaaaactaat
     3541 tatttcctac atattaaaat ataatacttc catttccaat aaaaatacat ttataatagg
     3601 aaagataaac agctgaaaag ggagatttca aatgaagaaa aaaacgttca aaaaactatt
     3661 gtttctaggg ggcacagctg ctcttttatt aagcggtaca agttattacc tacatatcca
     3721 ttctccagaa catacaatga acactgcaca aaaaagttca acacaaaaaa cgaaaaagac
     3781 aaaagagaaa gcagaagttt tactagatgt tccattagag agccagtttg attctccttc
     3841 tttagaaaat ggctgtgaag tcacttcgct ttctatgctt ttatcttttt atggttatga
     3901 aacaactaaa aaccagttag ctgagcaatt ggattacgtc cctgttttca atgcagatgg
     3961 gactcatggc gatcctaatg aaggatttgt tggtgatatc agtggcggag actgggctat
     4021 ggtcgtctat gttcccccag ttgcctccct tgctcagcaa atcgtccaaa cggattatca
     4081 cacttttcca aaaaccgatg ctcaactcga tgatatcaaa aaagcactat ctaaaggaaa
     4141 tcctgtctgg acttctgtga ctatcaattt tgaagtccca gatgaaactg attttatgac
     4201 ttggaccaca aataatggag aagtaagagt cactcctctt gttcatgctt gtgtagtcac
     4261 tggatatgac aaagaaaata tttatgtcaa cgatccctat ggtgtaaaaa atcgagcagt
     4321 accgatcaac gatttttcgg cgattttcac tgcaatgggt ggacagatgc taactttgga
     4381 gaaaagctag taattcaaac aaaaatccct tatactcaag ataccaaacc tttgaaggga
     4441 gcgtagataa tggaaaaatt cacacataaa aaaatggatc caaatgaaat tccgattatt
     4501 tttgtccgtg actgcaaggg aaatgttcaa ggtaaagtct ctattaatga gtggaacgag
     4561 cgtcgcagac ctgctaccct caatgaactg gaaatcaaat tgtatcgtca atctcttgtt
     4621 tattacgcag atcaagagta cgagaaagcc accgatttat tgaaatttct aattgctcga
     4681 acagagtata ctcgctttga atatattgaa cgtttagcaa acatctatca tattatgaat
     4741 gaacctgtca aagaatatca gttattggac accgtcttgt cagtagcaga actgattgcc
     4801 cttcctgctg gattagaaaa gaaactagta cgccgccttt tacgagtaaa gcaacaacta
     4861 tccgatcaag aaaaataact tgcgtttttt taggaaagtg ctatgattat tttgttgaat
     4921 aaatgggatg tagccaaact ggtaaggcac ttgactctga atcaagcaat tgtaggttcg
     4981 aaccctgcca tcccaatttg atgtgcttgc tgaaaaaatg aaccccctgt aaaagaacaa
     5041 tctttttgca gggggattat tgtattattt ttactacttg tatttagttt acataattaa
     5101 attatgaata ataaaatcgg gcgtattctt aatacaaaaa ctgatttacc caataattgc
     5161 taatgctttc tccggaactt tttctctagg aacttcctca tacgtttcta tgtgtgctcc
     5221 tttattgcta attttcaaat aatgattttc ttttaacaca gaaagaccat taaattcaac
     5281 cgttcgttct ttcccattgg catcagcagc tttctgcaca taccttgctg taccatattc
     5341 atttacttcc tctggttttt gtgtctttac atagacctct cctttttcaa ctaatggatt
     5401 tagctgatca agtataccag ggatttctcc ataacttcct tcagtataat atttcagtcc
     5461 aaatagcaaa ataccactaa tcgccgccag tccaatcaaa tatttaatca ctttcatctt
     5521 tctacctcct tgttatatat tcagtatatg ggtcagttaa agaaattcca tccgtcccaa
     5581 gttggagatt tttctcctac tttagaagcg agaatcgagt gtttttttag taaaaatgat
     5641 cgttatttga tattattgac gtgtggataa atcagttttt ctcgttttgt ccatgtaaaa
     5701 aatcatgttg atagcaaagg atgtgttcaa aatgaatcaa gaagaattat ttcaaaaagt
     5761 caaggaaatg attaagaacg gcaatttcga tggcgcaaaa cgatttatcg aagaacataa
     5821 agaacaatta ggaccttata aagagaaagc ccaaaatctt ttaaaagatg taaatatcga
     5881 cagtgtcaaa aacaaattta aaaatctatt caaataagta aaactttcac ttttgtaaaa
     5941 tcaaaggagg acaatgctgc tgcatcgtcc tcctttggtt cttttctgaa tacttcatac
     6001 taaaataaac gtgtcggatc gtaatgataa gtcacattgc cgttcagtga ggcttttccc
     6061 accacatatt tacgattctc caacttcagc cacgcttctc gaaaagccat taattcttct
     6121 ctttttacat caatcttttc gatttttcca tcgatcaaat cttgaataag ttgttcatat
     6181 ggattcattt ttttcctcca tctgctgtca atcaataagt tgtaaaaata ggttcatatg
     6241 cttttttggt atctagatct tctctgactt tgactgtcgt ataaataatt ttttctactg
     6301 ggatactata ataacttcct tcaccattat tgaatcggtg aacgtctttc tttgctaaaa
     6361 taccatttat tttattcgtc agtacacgtt gttcgacact gttacttaca acatagtaaa
     6421 tcacccgaat attattgatc aaatgcaaat cgatttctaa cactacatga tccatgaaaa
     6481 tcccactcct tctttcactt tgattatagc aagtttctcc tctaatttca aaatcgatac
     6541 agattttacc ggataaatcc acaaaactgc ttgcgccatt tcgcacaaag tgttattttg
     6601 tatcatggac tttatttatc ggaggcaata gtatgatcgc gatcggtcaa tttgtttttt
     6661 atattccttt ttttattatg ataagcattc ttttctatta cataaaatgg acaaaaaaga
     6721 agttttcagt tttactggcc tctttacctg ctgtatattt tacttatcaa attttttctt
     6781 ttaggcattg ggaaacaacg tctgtattaa taacacacat catcgaattg acgctttcag
     6841 taatttttct tattatttgg atctattttt tatataagaa tcagaattga atccctcgca
     6901 tgtttaaaaa gaaaacgatt aaagatgcag caaatttctg ccgatcttta atcgtttttt
     6961 ctattctgtt ataccaaaaa aatgtttgaa tcggtgaagg atcgttcctt gttttaattc
     7021 tataaattct tgtgcgatcg ggtacttttc ttccaaattt tctttgttct tttcgatcag
     7081 gcttttcgct tcttcatatt ttttatctgc acatagtgct tttacttcct gtaatacttt
     7141 tcctgcttcc atttgcctca ccctcttgcc attttattgc tttaagtttt atttaagtta
     7201 tacgcattat tctagtttca tcccaaataa ccttttttca tttttactcc tcgaactaat
     7261 cagttttcta aaggctgatt ggttcgtctt ttttattttt cctccatttc attctgctct
     7321 tctgttaatt tatctaatgc tttgattgat gctgcggctc ttgcataatc atagctctgt
     7381 ataattccat aaatttatca ggcagaacaa accacgctgg atgataaccg ttagctgtga
     7441 cagggaatcc tttatcttgt tggttatctc catcccatct cagagcaaca cctttttttc
     7501 ctttccactt tactaaagcg atcgagtatc ccttctttgt ttgtgtgccg tcttcaataa
     7561 ttgctaaaat ttctattttt tcttttggcg cacggacttc ttgaggacga accattttct
     7621 attcctccct tatctcatta cttcacgacc aacacactgc aaggggcatg tgatacgaca
     7681 taagaagcgg tcgatccaac taatgcttgt tgtatagcac cttttcctgt cgctcccata
     7741 acgatcaaat caatattttc ttgtccaggg atgacattgg caatcaaatt tcttggatct
     7801 ccagtttcaa ctattgcgtg gatctcagca atgccgtact ctttggcatc attgattttt
     7861 ttcagcatgg ctacttctgt tctttgtttt tcatctgcat agatttttga aaaggcatag
     7921 gcactatggg tcagctcaac tttgttgatg attgacacga taaataagtg ggcttcattg
     7981 tcctttgcta agtcaagggc ttcagcgaac gctttgatcg attgtcttga tccgtcaact
     8041 gctaccatga tgttctggta tcttttactc attggaaccg cctccttttt cttttattgt
     8101 aacatctcaa gcaaaaatac aaaaaatata cgcaatatgt aaataaaatg atgaacaaaa
     8161 gcaatttctt tcaagttatt tatacatttc ttttctcatc agaacacctg ttctaatccc
     8221 attatttctg cattatgtga aattcctcat catttttcac atcgagcgaa catcattctg
     8281 ttacaaaaaa cgtggatttg tcataaattg tcatgcttct tttacctatg aaatattttc
     8341 acgtgttaaa gtattcctcg ttgaacacaa caaataaaac tttttaacga ataaaggaga
     8401 tttttcatga catcacttaa aactttactt tttggaacaa ctttggctgc cggcgctgca
     8461 ttcttcatgg gaacgactgc tcatgcggac gaagcttata ccgttcaatc aggtgatact
     8521 ctatcaacga tttctcaaaa atacgttggt gataactcct tgatcaatgc cattgcagaa
     8581 tcaaattcaa tttctgatat taacctgatc tactcaggac aacaattaac aatcccaaca
     8641 gaaggctctg cacaagcagc tgctgaacct caagcagccg ttcaagaagc accagtccaa
     8701 gctgaacctg ttcaagctga acaacctgtt gtacaagaaa cggttcaaac ggaaacacaa
     8761 gcagcgcctg ttgctgaaac acaacctgct cctgctgtaa cagaaactgc tgctactcca
     8821 gcaagtacaa gctctgcaaa agaatggatc gcacaaaaag aatcaagcgg ttcttacaca
     8881 gcaacgaacg gacgttacat cggccgttac caattagatt cttcttactt aaatggtgac
     8941 tactctgctg caaaccaaga aagagtagca gaacaatatg ttacttcacg ttatggttct
     9001 tgggaagcgg cgaaagcatt ctgggaagca aacggttggt actaagattc attatttgaa
     9061 cgtttaaaca cattcaaaat atagtaagag gtcatgcgat ttattctttc gcatgacctc
     9121 tttttgagtt taagtttagt ctttattcct taactatcgt ttgccagtat ttcttgtatc
     9181 agaatctata aatctactat ttgaatcaat ctattaggtt ttaaactgtc ccaccttcac
     9241 acaaattttt tttgatttat ttgaatctgg ttccgttgtt taaaattttt cctatattct
     9301 tttagataat atgttatttt ctttctcatc gctccaggtg taccttctct ttataaaaaa
     9361 acaaattatg cggctaagaa gactcgaact tccacgaggt caccctcact agcgcctgaa
     9421 gctagcgcgt ctgccaattc cgccatagcc gcatcacatc ttttagttta ggattacatg
     9481 tgttttttgt caagaacata tttttgttct ttttcatttc tgtacgccct cccttatgcc
     9541 atctacacaa ataattcatc cgagcaactc catcatctat tgagggttgg tgaaaaaatc
     9601 tgttttatcc atatgatcga tttcaatgtt aaacgaacga ctctgggatt agtaactatt
     9661 ttattttttt cttcatttct tttttcctct ttttctcgat tcagctatct tctttcattt
     9721 ggatattgat tatttcttct gttgattact atccttctgg aattctagac gctgaagtaa
     9781 ttcacgtttt ctttcttcta gagatcataa gtaacgaatg aacgaacttc aaataatttt
     9841 tttattgtaa ttcatatttg tattgttcga tgattcttaa tacgatatga cacaataaat
     9901 aaaaataggc atggctattt acaacaatag tgctatagta gaaaacaaat gaataaggtt
     9961 acttaaagag gtgaatacga tgaaactgat caaactatgg gaagcagatt taaagaaagc
    10021 ttatcagcta caaactagct ttggaccaaa tgagagtgga tttatcaaca atgcttatgg
    10081 ctatacattt gctgaatttt tagattatgt aaaaaaatgc gaaaaaacgt ctttaggaat
    10141 cgatcttcct gagagttacg ttcccgcaac cgtctttatt ttagaaagtg atgaacatga
    10201 gtatgtagga atttttaatt tgcgccataa actgaacgaa acattaagaa acggcgctgg
    10261 ccatattggt tacggcatct cccctaatta tcgtaaaaaa ggatatgcca cacaaggatt
    10321 agcattagta ctacaagagg caaaaaaaat cggcattgat gaggcacttt tgtctgtaaa
    10381 taaaaaaaat cttggcagtc ttaaagcaca acaaaaaaat ggggctgcga tttatcgtga
    10441 agatgagaaa gaatactata cgaaaatcaa actgatgtaa aaaagaagga ttccaaaagg
    10501 aaagggattt gaatgtcctt tatcaataga acacatttat ttaattaact tataatatag
    10561 cagacaaaat tttataaaca aagaaacctt ttatctcttt tcttctagaa aggataaaag
    10621 gcttttttgt ttttcctatt tgcttctcat agctagtcag ccaagatttc tatcgtatcc
    10681 ccaacgcaat ccgtgcataa cggctcatct tatctgtcgt ccatgctgga taccagacta
    10741 gtttgacttc tgctttcgtt acttctggca cttcttttaa tgcgtcatgg atagattctg
    10801 ttaaaatatc tgctaatgga cagcccatag ttgttagagt catcttaatg actgtttctc
    10861 cattttcagg attgaattct atatcataaa tcaagcctaa attgacgatg tcgattccta
    10921 attcaggatc aatcaccatt tccaaggcag caagaatacg ttctttgatt agttctattt
    10981 cttgtccaga ccgttcttgg tttgcttcgc tcatcgtacg acactcctta acacgatttt
    11041 tatttatcat actctttttt tagctgcttg taaatgagaa tttagaagta agattctcgt
    11101 ttaaatttat aaaaatgttc ttattagatg taatagatta aatttattct aaaataaacc
    11161 tgattcctca ttttttttgt gaacgatttt ttatttctgg caatacgcca gttgttcgat
    11221 acattttttg ttcgttttca tttgcaaacc ggccaaatac tgaatgagtt ggtaaaatat
    11281 tgataaatgc atcgtcgtcg atttcatgaa cgatctgatc aagatcatac atttcgtagc
    11341 gggtgatgac catcatgatc atgttccctt gtttttttga atagccaccg acagacggca
    11401 gtaatgtcat tccacgtacc atccgttttg ctagttcttc tgttacctct tctggcttga
    11461 cggtaacgat cattgctgtt actttttgat gactcgtgtg gatggcatca attacttgag
    11521 tcattgcata aatggaaata atcgtataca aggcactttc ccagttaaag aagaagcctg
    11581 cgatgactac aatgatacca tttagaatca gcatgtagtt tccgactgtt tttccagttg
    11641 tttgtgaaag tacaagagag atgatatcca tcccaccagt tgtaaagccc atttttaaag
    11701 ataatcctac gccaagacct aataaaacac cgcctactag ggcattcatc aaaatattat
    11761 cagtgatctg tccgactgga agcagcatcg tcatcaccga tacacataca acattcacaa
    11821 aactaaggat cgttgctcgt tttcctactt tgagaaaccc taatacaaac acagggatat
    11881 tcaaaagaaa aataaatgtt cctgtgtcta tcttgatatg aaaccattca tataaaagcg
    11941 aggaaatgat ttgagcgatc ccattcatcc ctgcagaaaa gacattggct ggaatcaaaa
    12001 aataatttaa agcgaccgca gcggtcaatc cggttatcaa aataaccact attttcttta
    12061 atctttcatt tttatgatac gcagtcataa ttttactcac aagcacctct cccctacttt
    12121 ggtattccaa atgtaagaat aacagtttat ctattaaaat aaaatacttc gaactcaaat
    12181 gagaagaatt ttagcaaaca ggtaagaatc tgccctaatc ctatgataag atagatgtat
    12241 ggtaaatatt tatatgtata tcaggagggt tcctatggca aaagatgcta gcttcgacat
    12301 tgtatcagaa gtcaatacag aagaagtaaa aaatgcgatt cagcaaacaa caaaagaatt
    12361 gtccaatcgc tttgacttca aggattctac agtagaaatc aaattagaga acagcaatct
    12421 agttgtattg agcgatgatg atttcaaaat cgaacagatc aaagatgtat tatttggtaa
    12481 gctgatcaaa agaaatgtgc caatcaaaaa tatccatttt tccgaatcag aacacgctct
    12541 aggtggcaaa gctcgacaaa ctgccgattt ggtcaacgga atcgatcgtg aaaacgcgaa
    12601 gaaaatcact acagctatca aaaatgaaaa actgaaagta aaagcacaaa tccaagaaga
    12661 tcagattaga gtgacaggta agaaccgtga tgatctacaa gctgtgattg ctttattacg
    12721 taaacttgac ttaccaatcg agttgcaatt cactaactat cgttaatcaa aaaacgaggc
    12781 tgacgtctgt cattcctcgt ttttttgatt tactgcttct tttgataacc aaaaacgctg
    12841 tattccttct tccaattccc caacacttcg tacttctctt gctgtttgcc aatgttgtgg
    12901 gaataaacgt cgataagaaa aactagaaaa tcgttgatct gccaatacaa cgattccttg
    12961 atccgccatg ccacgaatca ctcgaccacc agcttgcaag actttgttca ttccaggaag
    13021 ctgataagcg taagcaaatc caaggtgttc cttctcatca taatatgatt tgatcagttc
    13081 ctgctcatga ttcatctgcg gcaaacctac acctacgatc atactgccga tcaatcggtc
    13141 ccctctcaaa tcgattcctt ctgaaaaaat cccgccaagt acgcaaaatc caatcaatgt
    13201 ttcagcggga tttgtttgaa attttgttaa aaatcgttcg cgttcttcct cattcatgtc
    13261 cgtttcttgg attagcacat tgctgtcggg atattgctgt ctgaatgctt ccaccgcaag
    13321 atctaaatat tgataagaag gaaagaaaac gaaataattc ccgacctttc catcagcaaa
    13381 agcatgaatc gtctctacta attttgccag actgtgttcc ctttttcgat aagtcgtctc
    13441 taggtaattt gcgatgaaaa cttgctggtt tccttctggg aaaggactcg gcagtttgta
    13501 agccagactt ttttgtcccc ccagtgtttc ctgataataa gagagtggtg aaaaactagc
    13561 agaaaaaaga atactgcttt ttcctttatc caacgactgc tcaagaaaca agcttggatc
    13621 aatacaaaac tcttttacta tcagatcgcg atacgttttt tcgactgttg tttcgtagtg
    13681 atcatcataa aattcactga ccttcaaaaa atgaagcaaa tcaaaataat aaggaagcaa
    13741 ttgttcttgt gatgggtgct caggaaattc tgccagccat tctttaattt tttcgcttaa
    13801 ttgataacct gcctttacta aagattcagc cggtgctttt tgatgatgat aatcccaatg
    13861 atcttctttt gctatttctc ggatcgaatc aaattctttt aatagtttgt tgaaacggcg
    13921 atgaagtttt ttgaattcct ttggtatagc ttccttactt cgtttcgttt tttcataaga
    13981 tagttctgcc gaatacatct ctcgggaacg attcaccaaa ttatgtgctt cgtcaatcaa
    14041 aaacagatag tcctcgtttt tttcatcttc aaaaaaacgt cttaaataaa cagttggatc
    14101 aaataaataa ttgtaatccc caatgattac gtcacaccag atactgacat ctaatgatag
    14161 ttcgaaagga caaagtgtat gctttcttgc ataagtttcg atgacttcac gagtgatctg
    14221 attctcatga ttcaaaagat cccataaacc ttcattaatc cgattgtaat aaccattggc
    14281 atatgggcac tgatctggat tacaggtcgt ctcatctaaa aagcagatct tgtctttcgc
    14341 cgtcaaagtg acacttttta cttcagctcc tgtatctttt aatgctgtca tagcatcttc
    14401 agctacttgt ctagttattg ttttagccgt tagataaaag atcttttctc cctcttcttc
    14461 ccctacagct ttcaaagcgg ggaataacgt agagattgtt tttcctgttc cggtaggtgc
    14521 ttctacaaac aatttctgtt tcgtacggat cgttttataa gcagctaccg ctagttcacg
    14581 ctgacctttc ctatactcat catgggggaa tttcaaagcc atcaaagagg cattgcgtac
    14641 agtgcgccag ttttcttgaa aaacaagcca ttctttataa tcttcagtca gctttttaaa
    14701 aaaagtttct aactgctctc ttgtctgatg ttcaaccttt ctcgtgatca cttcttctgc
    14761 cgtctggaag taagtcaatt gcagatttat ttcttgtaaa tcatgttctt gactatagat
    14821 ataggcatac acccttgctt gatgaaagaa aagttccact tgttctggtt ctaaatcttc
    14881 aaatcgtggt tcggaggttt tgatttcatc tatataataa ataccgtctc ttttgaaaat
    14941 accgtctgca cggccttcaa cgatcaggta atattcatct aattgaactg ttgtttttaa
    15001 aaagacttct ttttcatagt tttctcccgc atctttttgg agcttgcggt ggattctcgc
    15061 tccttctaat gcagtatggt tacttttttt acgattgtcg atacttccac gtcgcaaaat
    15121 aaattctact aagtgccgca cagatatttt tgactgtttg atcatttcca ccacctcttt
    15181 ctctctaaga ttacctgaaa aaacctagtt tagcaaaaag agctctcttt ccaaacataa
    15241 aaaaacaccc tgctgattag gcagggatat aggatataga atttggattt ttggatgaat
    15301 ctaatgtaac aaggacatat taaaatgcta tgaaaactta ctttccttct ctttagaata
    15361 tccaaatact tttcatatag tctgataatt cagataagta aagagaaata agtacctgtt
    15421 tttgtttcct agcaatgaat gcgttatact aatggatgaa agaagttttg gctatcaagg
    15481 aggaatgcac atgcatatcg aaagattaaa aacaggaatg attgaagaaa actgttattt
    15541 ggtctacaac gaagaagcac ttttgatcat tgaccctgga gaagatgcgg aacgaatcaa
    15601 acaagaaatc aaaaaaacaa accaacagcc ggtagcgatt ttgcttaccc atactcacta
    15661 cgatcatatc ggtgcagtgg aacctttacg cgcgtattat caaatcccag tttatgtcag
    15721 cccactagag caaaaatggc taggtgatcc gattttgaat ctttctggac tcggtagaca
    15781 tgatgatatt gctgatgtta ttgtctcgcc tgcagaatat gaatttgaaa tgaaaactta
    15841 tactttagga aacatgtctt ttcgcgtcgt ccctacccca gggcattcta taggaagcgt
    15901 cagctttatt tttgatgatt ttgtcgtttc tggcgacgcc ctgtttagag gaagtatcgg
    15961 tagaaccgat ctgtatacag ggaatttaga acaattactt catagtattc ggacccagct
    16021 gtttgtatta cctgatgaat ttgcagtcta tccaggacat ggcgatgcaa cgacgattga
    16081 acaggaaaaa aggacaaatc cttttttcaa tcgttaaaac gacttaggag gagaataaaa
    16141 tgacagaaac tacactttat atcgtacgac acggaaaaac gatgttcaat acaattgaac
    16201 gagtacaagg ctggtgtgat acacccctca caaagcaagg acaagaaggc attcattatt
    16261 taggtcgcgg gttaaaaaat gtcgactttt catttgctta ttctagtgac agtggtcgtg
    16321 caatcgaaac tgcccgtatt attctaggag aacattctaa gggaaaagaa attccttatt
    16381 ttattgaaaa aaggattaga gaatggtgtt tcgggtctct tgaaggtgga tatgacatgg
    16441 aaatgtgggg tgtgatccct cgtgtattga attttaaaac atatgatgaa atgtttacca
    16501 cagaagtttc ttttgaacaa attgctaatg ctgtatacaa cttagatacc gctgggtggg
    16561 cggaaactta tgaaacattg cgagaccgtg tatggacagg atttgaagat atcgcccatc
    16621 actgcgaaaa aaatggtggt ggaaatgttt tagtcgtatc tcatggtttg acgatcgcct
    16681 ttttgcttaa tctgatcgat cctaaacagc ctgttcgtgc tgggctttta aatggcagcg
    16741 taacaaaggt cacttatgca aacggtcgat tttctatcca cggcatcaat gatacgtctt
    16801 atatcgataa cgggaaaaca catagtcgcg actcgtttct ataatgggga tattttaatt
    16861 tttaccagag aatcataaaa ggcaaagtct gaacgagggc tttgtcttct tttttctctt
    16921 cgtgtactta tctgctttat ttctcaagtt tttcttaata ttaaaaaaca gattgggttt
    16981 ctcaaaaaat aacggtatac tataagatgt atcttaattg ggaaggaagg aatttatgtt
    17041 ttttgcaaat attatcaaag cagtgattct cggtattatt gaaggaataa cggaatggct
    17101 gcccatcagt agtactggtc atttgatcct agcagatgaa ttcatcaaac tggatgccag
    17161 ttcacaattt atgtcgatgt tcaatgtcgt tatccaatta ggggcgatct tggctgtcgt
    17221 cgttctttat tttcacaagt taaacccatt ttctccaagt aaatcaacgg tagaaaaaaa
    17281 agatacgtgg acactttggt ttaaagtgat cgttgcttgc ataccagcca tcatcattgg
    17341 tttgcctttg gatgattggt tagaagcaaa tttccacaag ttcttaccag ttgccattgt
    17401 tttgatcgtt tacggtattg cctttattat tgtcgaaaaa cgcaacaaaa acaaaacacc
    17461 tcgttggact tctctgaatg actttacgta ccaagcagct cttcttgttg ggttattcca
    17521 agtcttggca cttgttcccg gaacatcccg ttctggcgca acgatcctag gatctatctt
    17581 gattggtgct tcgcgttttg tcgctacaga gttttcattt ttcttaggga ttcctgtcat
    17641 gtttggcgca agcggcttga agatcgtcaa atatttagct gaagggaatt cattcaaaat
    17701 ggaagaaact gttgttcttc ttgtaggaac attcgtatct tttgtggttt ccgtcttagc
    17761 tatcaaattc ttactaagct atttgaagaa aaacgacttt accgcttttg gctggtatcg
    17821 tattatcctt ggtatcattt tgattggtta ttggtttatt gcaatgtaga aaaaaccaga
    17881 acacttctct tatttgagaa atgttctggt tttttatttt ctttaataat aatcattata
    17941 aataataaaa acaacatcaa gcttaatcac caaatgataa ccattatcgt tctcatttag
    18001 ctgttattat tatcaattac atttttatta tgctatcctt gttttgacaa ggaggtctaa
    18061 taacgatgac taatcagaaa aaagcttttg cagcaacaat cggctgcctt ttatttatga
    18121 tcttcggttt tatcttcgac cgattctctc ttaccatcac cccacttttt tatatcagtg
    18181 ccattatcat cggtggatat aaacaaacat cggaaggctt gaaagaattg tggaatgatc
    18241 ggacactgaa tgtggattta ttgatggctt tagctgctat tggtgcctgt ttgatcggta
    18301 attactttga aggagcaatg ttgacattca tcttttgttt aagcggtgca ttagaggaat
    18361 acacaactaa taaaagtcaa aaagaaatta ctgctttgat gaatcttcaa ccacaaaaag
    18421 cccaattatt aaaagaaaat ggacaaatgc aagaagtaga tgtttctcaa ctaaaggtgg
    18481 ataacttggt atttgtcgct aaaggagcag ctgttccgat agatggcttt ttagaaagca
    18541 cacaggcaac gatcgatgag tctgcattaa gcggtgaatc tgtgcctgta gaaaaatatt
    18601 taggcgatga gatgtatgca ggaacgctga atcaaggaaa tcccatcacg attcgagtaa
    18661 caaaaacgag ttccgaaact gtctttgcta agattatcca attagtagaa gaagcgcaga
    18721 atacgccaac tcaaacagct tcatttatcg aacgaatcga aaataattat gtaaaattga
    18781 ttttgcttgc tgttcctcta atgatccttc tcccccactt tttcctaggt tggagttggg
    18841 atgaaagctt ttatcgagga atggtattat tagttgtggc ttctccttgt gcgcttgtcg
    18901 catctgctac accagcttct ctagctgctc tttcaaattc tgcaaaaaat gggattttaa
    18961 tcaaaggcgg tatccattta gaaaagcttt ctgaattaaa agcgattgcc tttgataaaa
    19021 caggaacgct cactaaagga aaaccagttg taactgacag ctttttcttt gatgaaaagg
    19081 atttggcaca acaacttctt gttgctatgg aacaaaaaac gacgcatcca cttgctcatg
    19141 cgattttgca atatttcgat tgcacaatac ctgaagaaat ccaatactta ccaatagaag
    19201 aaattactgg ttttggatta caaactacct atttaggtgc gcaatggaaa gttggcaagc
    19261 acgcatatga tcctgagacg atgataatca gcaaagagat tgcggaaatg atcgaacgtt
    19321 tggaaaatca aggcaaaacc gtgatttatc tttctaaaga tcagcagtta attgctgttt
    19381 taggtctgct agatattcca aaagcaaata cccaacaagt aatttcctac tttaaatccc
    19441 aaaacatcca tacaagtatg ataaccggcg accattctgg cacagcaaag gccattgctg
    19501 aacaagtagg gattgaacat tactatgcaa gctgtactcc ggaagaaaaa acacaactag
    19561 tcaaaaaaga gaatgaactt taccaagtaa atgcgatggt tggtgatgga gtcaatgatg
    19621 cgcctgcttt agcagccgct tctttaggtg tcgctatggg gcaagggaca gatgccgcta
    19681 tggatatcgc agacatcgtc ttaatgaaaa gcgacttaaa taaatttgtc tacagtcatc
    19741 ggctatcttt aaaaatgcgg cggatcatca aacaaaatat tattttttcg attcttgtta
    19801 ttctcttgtt gattgcttct aacttcctgc aatttttaaa tctacctctt ggagttgtag
    19861 gacacgaagg aagcacaata ttggttattc tgaatggctt gcgtttacta agacctttac
    19921 ctgatctttc tgattcttca aaaaaatgta agtcttgtcc actatacaaa gcgcggctgt
    19981 cttctgtcaa ataagcaaag tgttttttta tgattttgtt tattttatga aaaaaacagc
    20041 ttatgaatag gtcttgaagg atgaattcct acttttgtaa ctttctaaaa acatgttatg
    20101 attgtttcga agaaagtgag gaatatattt catggaaagt tggctttttt taggaattat
    20161 tttacttgta gcaattttag ctaaaaatca aagtctgatg atagcggcag cttttgtttt
    20221 gattatgaag ctcataccag cctcccgttc ctttttccct tggcttcaag gcaaaggaat
    20281 caatattggg gtgacgatca tcacagcggc tattctaatc cctatcgcaa caggagaaat
    20341 cggtctacgt gatctattag aagcctttaa atcccctatt ggctgggtag ctgttttttg
    20401 cggtgggcta gtggctgtct tatcttccaa gggtgtagga ttgattgctt ctgatccaca
    20461 aatcactgtt gcacttgttt tcggcacgat tttaggtgtt gtcttcttaa gaggaatcgc
    20521 cgccggaccg gtcattgctt ctggtatcac ttactgtatc ttacaagtat ttgctttagg
    20581 aaaatagaac aaattttgtc tattttagga gattcttaac acccccaatt tactgatccg
    20641 tgatatactg acaacgaggt gatacaatgt tcgaaaaatt aaagtatttc ataggaacaa
    20701 tcggctggtt tcttctagcg gtacttttga ttctgggctt agcttatcta ttatttcctg
    20761 atttgataca aaatgtgttt gatactgctt tttgattgac ctattaaaac gatatagggg
    20821 atgctcctgc gatgcagggg ctttttttaa tcaatgtttt gtaataattt aggccgtgcc
    20881 aatgagactt cctatagaat tcgatgctct tttttctttt tggctcttct gctctttttt
    20941 gttatactag attacagtgg acaaaagaaa gaatgatcgc atccacttca acgaatatca
    21001 aaatggaaga attagtgcct gttttcaggt tactttgaaa agaaaggaag acgcttgtgg
    21061 aaacttttga aggtctttta attgatacgt acgttttaca agaacagcca atgatgctga
    21121 ctgggatcaa cttgcagctt gaggaccgtg tgatcaatgg cctgcttaaa gatcgctatt
    21181 tggcaaaata tatcttacgt ttgcccctaa ataaatatgt gctggaagta agtggcaaat
    21241 ggaaccgtcg gaaccagttg gtcataaaaa aaatgttgat aaaaaatatc gatgaataca
    21301 ttaaaataat cggtacacca gaatagcctt tactgatcaa aggatactgg ttataaaata
    21361 actgcagttt cttaatagaa aaacaaagaa caacagggaa tcgtatccct tttcaaaaaa
    21421 aactttgcaa acggttctct ttgttatata ataacttagt accaaacatt cccattcaaa
    21481 ctttgtttaa atagataaat aaaaatctag tttggtttga cgctattgcc tcccacaata
    21541 gcgtcttttt gatttttttc agcttgtact atccgttttt actgaaaaaa aatcctaata
    21601 aaagactgtt aaggaaaaaa acttgtcatg ttcatattgc aaagcacgct gcctttaggt
    21661 ataataatga atgttgaatt atgcggtaac acgcgtaaga acttaagtta tcggaggtga
    21721 aactaatgcc aaacattgaa tctgcaatca aacgtgttcg tacaagcgaa aacgctaatg
    21781 tgaaaaattc atctcaaaca agcgctatgc gtactgcaat caaaaaattt gaagatgctg
    21841 tagcttcagg tgctgacaac gtagatgcgt tatataaaga agctgttaaa gctattgata
    21901 tggctgaatc aaaaggtcta atccacaaaa acaaagctaa ccgcgacaaa tctcgtttaa
    21961 gcaaaaaaat cgctaaataa aagaatcggc ttcggccgat ttttttattt gtcaaaaaaa
    22021 ggacaaaaac aaacgacctt cccgcatgct ttgccctcgt ctttcttctt atcgatttct
    22081 taacaactgc cctgtgcgca aaacgaatag ttgaaaactt aattcttttt cgatttgtcc
    22141 cgttttgatt tgataatcca tctcaactaa ttgatcaaac aactgtacca gcaaatgttc
    22201 atcgaatttt tttacttcct gcatggcaag ttttacacga tatggatgga ttttcaatgt
    22261 ttcagcaata tttgcctgct gataaccaat ctttacaaga aattttgtct gtaaaaataa
    22321 acgtaattga gaaagcaaaa tcgcattaat tttgattgtt tcttcccctt gcataactaa
    22381 atcttcgtat aaacgcaaag cttgttccgt cttccctttt aaaatatatt gggtcatgtc
    22441 aaaaatatta tgttctaacg ttttaggaac taattcttct acttctctta ccgtgatttg
    22501 ctgttgattt tgtccataaa ggaccaattt ctgtaactct ctcatcattt tggataaatc
    22561 taagtcggtc aacctcaaga ataaatcaat tgcacttcgt tccattttga ttgaggaatt
    22621 ctctaaggta ttcatcagat attgacgtac ttctttttca ttcaactgtt ggacattgat
    22681 gataattgct gtttttttca attgtttcgt tacttttttc cgttcatcca acttttcata
    22741 tggcgcaaag aatactaata cagtcgattc taatggttct ttcaaataag ccgtcaataa
    22801 atcagtattt tgttcgattc cattgtttac tttttcacct gttaaaaaat aaggattctc
    22861 tacgaatact aaccgttgat ctccgaaaaa cggcaacgtc tctgcttcag ctactacctc
    22921 atctaaactt gcattttcca tgtcaaaact taaaaaattt aagtcatctt cgccctctaa
    22981 ttggattttt ttgacaattt ctgtccgaac ttgatcttgg agaaactttt ctgttcctaa
    23041 aatcaagtaa caagatgcaa gtttttcttt acgtattttt tgtaactctg cttgtatact
    23101 caaattactc accactttca aaaattatcc taccatgagc agatgagaat tactagtcta
    23161 tcattgtttc cactagccca tgaggatgaa aaactggatg ccagcgatag gtgatcattc
    23221 cttgttgatc cgttcgccat gtttttatct gattttcttc tagtgtctcc aatacttcgc
    23281 tgtgcgggtg accataacga ttatttacgc cgcaggatat aatcccatgt tttgcttcaa
    23341 tatgggaaag aaaatctgtg ttacttgacg tacggctacc gtgatgacct aatttgacta
    23401 catcggcttt cagattagga taaatcaaaa gcaattgttt ttccattgct tgattcaaat
    23461 ctcctaaaaa taaaaagcgc ctattgttat attccatcca tagaccaatc gaatcttcat
    23521 ttcttccctc tcccttttca aaaggagtca atacataaag atcataataa ccgctgatcc
    23581 tgtccccatg tttgatttca atgatctcag taccattttt ttgagcttca gataaatgcc
    23641 tttgtaatgg ctcatttcgt ccagcgcccc aaccgatata aatttttttg atagtaaaat
    23701 gctgagataa cgtgggtaat tctcccacat gatccgtatc gtcgtgtgtc aagatgagtt
    23761 tatcgattac acttatcccc tgacctttta gatatggaac gatatttctt tcagcaggag
    23821 gacgtatcat accttgcgcc cacttttctc tttcaaagtg taactgacct ccagtatcga
    23881 tcaaaatcgt ttcttttcga aaaggacttt gcaaaaagat actgtctcct tgaccgacat
    23941 cgataaaagc gatcgttgaa gaaaagcgta aaaatggcaa agtcaaaaaa ataaaagaaa
    24001 aaagaccaac ataaaacaag tgtttcacag gttgttcttt caacctatcc atacaaatca
    24061 gtaatccgaa aatatacatc ccagatagca caaggggcaa acgtcctata atgagagacg
    24121 accctgaaga aaaatcgatt attcgctcaa ataagattaa tccctcttct atcaacaaaa
    24181 gtaaagtttc cggcagccag cgattgaaga gtgtgagaaa taacacacca ggaagaaaaa
    24241 gaaacttgaa taccggtgca atcagtaatg taaaaagact acctaaaata ggccactcat
    24301 aaaaatgcca tacaatcaac ggcatcgtga tcatagtaaa caggacgtga gaggccgttt
    24361 ttttcaacca atctccatca aaagaaatca ggataaacaa aaaactcatg aaaaaactaa
    24421 gctgtccacc cgcatgaaaa agaaatcgag gatcaaatag taaaagaagc caaaagacaa
    24481 ctgcaaataa gtccatggtg gaataatgct tattcagcaa tttgactagc aatcgcaata
    24541 aaaacagcaa actagcacgc aaaacagaaa tagaacttcc tgcaatagaa acataacaga
    24601 tagttagtag actcaacgga ataatactga cgtgtagtgg ccatccgata cgtcgaaata
    24661 aataatacag ccaccctaaa taaaattgga tgtgtagacc cgatagactg aacagatgca
    24721 gcaaaccact ctccctaaaa atttcttctg gttctctgaa tcctgcatct ttatagcccc
    24781 ataataaaga attaatatat acacttgttt tttgcggaaa ttcagattgg acaaaggaga
    24841 taaaagatcc tctttttctc tgaagccagt ttcgccagtg attttgcatg gtgatctgtt
    24901 caatcttttg aatttggaac cgtccagaaa ttctatggtt cctgaagtaa gcttcttggt
    24961 caaaattata aagattccgc ttttttgctg gagagatgaa ctcgccttca gcagtcaatt
    25021 ctattccctt tcctcggaag ttaagccatg ttttcaattc tgcttctgtg tttacttgat
    25081 aagaaagctg gagcttttgt ttattctctg ataaccttcc ttccattgtc aaaaaattac
    25141 catttgcacg aatcgtatct gtaaatacag taatttgcgc agatgttgtt ttttcctcta
    25201 aaaatgaata ctcttgtagc ctataagaaa tggataccgt tatgctacac aaaatacaca
    25261 agtacgcgat aaaacgtcct tcttttagcg aaaaccataa aaaaattccg gcaagaagca
    25321 aacgataacc ccaattgtca gtgtaataca acaaacagat aatcatcgac gtaattgccg
    25381 gaaaaatcaa ccgatttcga acatgccttt ctaaaacgct agacatgttt tcctgttaat
    25441 tcattttgaa gttttgaaaa atgctgtgag tctaaagcaa cttggtgtac agatacacct
    25501 aattgttcga tcaacgcttg ggcataagga tcatttcgat agtcatggag ataattgatc
    25561 cctttcacac cagcttgcaa caaagccttt gtacaggcca aacatggaaa atgtgtgaca
    25621 tagatttctg aaccttccgt cgggatacca agttttgcac actgtaggag tgcattcatc
    25681 tctgcatgga tcgttcgcaa gcagtgtcca tccacgacgt aacacccttc atctatgcag
    25741 tggacatctc cactgactgc tccattatag ccgccagcaa tgatcctttt ttctcgaacg
    25801 agtgtcgctc ctacttctaa acgtgtacac gtactacgta aagataacag tactgcctga
    25861 gccataaagt actggtccca aggaatgcgt tcattatgtg acttatcagt aactttttct
    25921 ttattcgtat cgcatgcttt tgaagatttt tctaacatgt tttatattcc tccgtttttt
    25981 caagttgatt aaaaagtact cattgcttaa acaaaatatt ctttaaatat aacgaatcat
    26041 cctgtctgac aaaagatcct acccttcact gccgaaatga agtccgtcat ccattagccc
    26101 attataaaaa ttcttcgaat ccatttgttc aagaaattcc gtataaaaat cgatacttca
    26161 caatcatggc gttttgctac ttctgtgaga acagagatat attctttgat caacttgtta
    26221 ttccgatatt tttgttttgt ctcatcgact gctggtggcg tgataaagaa agcatgatca
    26281 gaactatagt cttttttcag ctgaactatc atccactgca gattttttgg tacgtttctt
    26341 tagaaagttg tttatgctct gctagatcat tcgtcccaat gagaataaat actttatctg
    26401 ctgtatagct aagtacatct ttggcaaagc gttctcgtag agcttgactg ttattgccgc
    26461 tgacagccgt attcataata tgaatcccag atattttatt ttggagatag acattcagca
    26521 ttggtttttt taatgtttct ttgcgaacaa tcaagctatt tcctatccaa aaatactacc
    26581 tcctcgtcct gccaagctct tagaattgga ttattcttag tatccattag cgtccattta
    26641 ttgctcgtgc cagtcgattt tgaatcattc tatttaattg taacgaagtt ttttagtttt
    26701 tcaactgtct tttcaccgat accagaaatc tcctgcaggt cttccacttt ctggaaggat
    26761 ccgttttctt ctctaaatcg aatgatttct tgcgctttga ctgatccgat cccaggaatc
    26821 tgctgaagtt ctgatggagt ggctgtattg atatttattt tgggaggctc ggaatctgct
    26881 gtaggctgtt ttccttccga ggatgccaac tgatcaagat gttctggcag ctcttcacct
    26941 acagcaggga tatataggac ttgctgatct tctatcttcg cagaaaagtt gattcgatcg
    27001 ctatccgctt cttctaataa tccacctgca cgctttagta catcatagac ccgttcttct
    27061 gaagaaaagg aatagatacc aggctccttc acacttcctt tgatatcggt gtacatgacc
    27121 tttggacgag catcctcttc tacatcgttt ccttcagctg atggatcttc tccactggaa
    27181 ctaaacgaag aaagtatttc ttttgcagca gtctcttctg tttctctata aaatagcaaa
    27241 tttgataata aaaaaccact tgcgatacaa aagataagaa ctatcataga catccaaatg
    27301 atcaatttgg gtgaagctag tattttcttg ctgatttttt ctatcattgt tcttttttca
    27361 aagaatgacc agtaaaaatc attcattact cctttcattt aaaattgaag aaacagtgag
    27421 ctctggcaaa atcgtccctt caacatctaa ttacgtcaat tttttctttt gtttttattt
    27481 ttatcgtgaa gatttttgac gaaaaagagg ggttgtgaca gaactcgtgt cacaacccct
    27541 ctttaattat ttagtttcat ttcattttct ctagatagtc aagcgcttct tgtactgttt
    27601 ttactggtac gattttcatt gaggaattca attttttagc ggcagctttt gcttcttcgt
    27661 agttggtttt tatttcagga tattctttct taacatcgtc tgaaatcgta tcatctggtg
    27721 caaagaaaat ctctacgcca gctttatccg cacttgccac ttttttatcg attcctccga
    27781 ttcggccaac ttctccttca ctgttgatcg ttccagttcc tgcaatttgc ttaccatgtc
    27841 gcaagttttt accagtgact tgttcataga tttctaaagt gaacatcaat cccgctgatg
    27901 gcccaccgat agagccagaa ttaatacgaa catctgtatc tgattcgatc tcggtatggt
    27961 cagtaagcgt gatacctatt cctgcctttt tatctgttgg taactcgatc agatcaccag
    28021 aagctgtttt ttcttcacca ttatgcaaat aactgatttc gattgtttgt ccaacttttt
    28081 ggctttttac ataatccata aatgcttctg tactttgaaa gcttttcccg tctacttttg
    28141 ttactgtatc tccaactgaa agcttgccaa agaaattcga tgttttctct acactcatga
    28201 catatacgcc tttgaattcc attttataag gcttgtctgc aagttttaac gcttgttcga
    28261 ttgctgcatt ttgggaagaa tccatataat actgttgcat ttgattatat tcttcatttg
    28321 tcgccccacc agtcaattct tcttcactga tcaattcttc aaaaggggtc attttagctt
    28381 ttaaagctaa gaaacctgta gcttgcctga taccaacaga ggtaagagag aaagacccag
    28441 aacctttatc ttccttatca ttgaccgtaa ttagttcttt cagatcgatc gtggctcccg
    28501 gtgattctac ataatacggc aagggaacta ctacaaatcc aatgatcaac attccaaata
    28561 tgataatcag tactgttttc aaccattgtt tagctttcat ttgattcacg ctttccagct
    28621 aaagcttcgt tgatcactgg cggtaagtag ctgctcacat ctccgccaaa gtgcagtact
    28681 tcttttaaaa tactggaact cacgtgacta tattctggtt ttgctaataa gaagacagtt
    28741 tccaattcat catatagatg atgattcatc tgagcaatct ctcgttcata ttcaaagtct
    28801 ttgatacttc gtatgcctct gatcaacgca tctgcaccaa tctcttttgc tgtttctacc
    28861 gtcaattgat tttcttgatg catgactttt acattaggaa gatgagaaac agcttttgtg
    28921 atcaatgtca ttctttcttc tgggggaaac aaacttttct ttgaagtatt gataaaaaca
    28981 ccaattacta cctcatcgaa taatttagcc gcacgttcca ccgtatctaa gtgacctttt
    29041 gtaaaaggat caaaacttcc tgggaataat gcacgtttca ttgatttccc tcttttctat
    29101 agatagttac ggccgttatg ccataaatct gttttcttat ttgatggaat ccagccacag
    29161 tttctggcaa ttcgactgtt ttatccgttt cgcatacgat aactgcggtt ttagaaaaaa
    29221 gtcccagttc ttccatttta tggatttgat cgattatttt ttgttttgca tatggcggat
    29281 caagaaacaa gtagtcgaat tgttgtttct ccgctgctag ccgttcgatt gctttgtccg
    29341 catcaagttt tattgtggta aatttctctg gttctttcgt aatttcgatg ttttctttga
    29401 tgatttttag cgcttggtaa tttttgtcta cgcataccgc atgactgcag cctctagata
    29461 ctgcttcgat agctaaacca ccgcttcctg caaacagatc caatactgtc tctccatcaa
    29521 aatatggtcc aatcatattg aatatggatt cttttacttt atctgtagtt ggtctggtgt
    29581 tcgcccctgc taaacttttt aaacggcgcc cgccataatt tcctgatatt atccgcatct
    29641 actcactcct tagaaatggt actggtacta gtataccaaa aaaatacttg gacaatgatc
    29701 aaaaatcgat cgttatccaa gttatttttt atttaaaaac tgctcataag agatttttaa
    29761 agatgttcag ctaatcggat ttctgtattt agctcttcaa tttcgaaacc ttcgtctttt
    29821 aatactgttt tgtttcctat tttttcggca aaattcattt cgatatccgg tcggtaagaa
    29881 cgttctacgt ttcgaacaaa atgtaattta cggattcgtt cttctgtttc ttccaatgtc
    29941 tcttcattta agtaaagcac gacatatttc attcttcttg agacataatg caacaagccg
    30001 aactttttca gattctttaa ttgttttaag ctgtagaccc atacgatcag cccgcgtcgt
    30061 tttgttattt caaattcact attgtctaat tgcatgacaa ttacctccgc atccaaagtg
    30121 ttttttcgtt tcaaaaaacg ggctacctgc atctactttg atttcattag aaacttcttc
    30181 ggcaagtact tggacaattt gatccaacag actttgcagc tgtgtttcac tatatcggaa
    30241 agctgcaaca tgctcatcca tatcaagctg tctttttgct tttcgaacag ctcgtttttt
    30301 ttcacgataa tcaggtgcat actcaccata tgccgctaca ttttcaaatg cttctttctt
    30361 agacaagaac gcttctttca actggcaaac ttttgcagat tcttccattg actgtttatg
    30421 ttcaagataa gaagccatcg ttttactctt ttttatcatt tcagcgactt ggaggcattg
    30481 atcctccagt tgaaacagct cttcgttaac gatcactgct atcactactt tctccgtttt
    30541 cttcttgcaa taagactaac atattttctt tagaaaaagc aatgcctaca gaatccgttc
    30601 ccgggtccat gaaacggtca tggttgtaag gatcgctgta ccaatataaa aacgaaaaag
    30661 tagcgtcaat cgccggatga ataaatagcc cactagtatt ttctaatttt tgtttactga
    30721 ttaacttctc caattcatca ttcgtcagtg agaatttcac tgtcgtttga gcactgccta
    30781 gcgatttttg ccaatcagcc atacgttcct ctgacaatat ttcctcaggc cttgtcaaaa
    30841 aatcatgtag tagcagctga ctgtggtttt gaaaggcaag tgtttgattg tatatgggaa
    30901 gttcgtcttc tcttctaagc atatttaata aagtcgtact ttttcgttct ttaacgcgat
    30961 tgattgattc ccaatcagcc gatttatctg cttgataatg tggaaggcct tcaccaaaca
    31021 cttgatatgg caatagtttc aaaagactat ctttatctaa atacacaact gaaaataggc
    31081 cgtttgttgt ttgatcaaaa aataaaatag caaaagtgtc gttatcaaaa gcaattagcg
    31141 gacgataatt catatcctct tccattagtt cgattccaac ttctgtatca tggtactcaa
    31201 aagtgaaatt agtatagata gtagtgattt tcgtaagatc ttgcatcgtc atccctaaat
    31261 aaaacggcgc gatatcagca ggccctgttt gcagtacttt aacagttgtg actctgctgt
    31321 cttggatgtt cgcttcaaat gtgagatgac tagctttatt ttcataatat cttgtttcaa
    31381 aaccaaatcc gctagttaat cgatcatagg cttggccaaa atccttttcc agctgatcga
    31441 tcggttttcc gatataagta gaaaaaccag ttgctttaag ctcctggtat ttccacgttg
    31501 tcatttggtt tgatatttgt tgatcagagt tttccttcac ttcaagtttt ggcggaaaca
    31561 agactggttc catgtagaat gccacaataa ctaatagcag aatcagccaa aacaaaccca
    31621 gtcttttcat gtttccccac ctttcgctta ttatttctca gtcacttcaa tcaaaaggtc
    31681 accagacgaa atagtgtctc ctgaagacac atatacatgt gcgacttctc cgtcaaaacg
    31741 tgcttcgatg gccgtttcca ttttcatcgc ttcagtaatc atcaacgtat cacctttttt
    31801 aacgttatcg ccttttttca ctaatacatc caaaacagaa ccagacatcg ttgctccaat
    31861 ttgttctcgg tttgtcggtt cagctttcaa tcgggtttgg accgtactga tgatcgaatt
    31921 atctttgata gtgatttcac gtctttgtcc attcaaattg aagaacagta cgcgattccc
    31981 ttcgatatcg ggttctccga tttcatctaa acgaatgata agcgtttttc cgcgttcgat
    32041 ttgtacattg attgtttcac ccaaacgtat accttggaaa aatgttggtg tgtccagtaa
    32101 tgtaacatcg ccaaattgat tatatgcttt ttgatagtcc aaaaagactt gcggatacat
    32161 caaatagctt aatacttcgt cttgttttgg ttcatagcca attttttctg ccaattcttt
    32221 ttttacttcg ttgaagtcga ctgattcagc caaaagacct ggacgttcat tcaatgcagg
    32281 tctgccttta agaataatct tttgcaattt tttaggaaat ccgccaacgg gttgccctag
    32341 ttctccttgg aagaaagtca caacagattc agggaaactt agtgtttcgc ctttttcata
    32401 aatatcttct tctgtaagat cattttggac cataaatagt gccatatctc caactacttt
    32461 agatgatgga gttactttaa cgatatcgcc aaacatcaag ttgacagtat gatacatttg
    32521 tttgatttca tcccagcgat gacctaatcc gacagctttt gcctgttgct gtagattcga
    32581 atactgtcct cctggcattt catgcatata tacttctgtt tcaggagcat tcaagccgtt
    32641 ttcaaacggt ttgtaataca tgcgcacatc ttcccaataa tggtttaatt tctgtgcatt
    32701 ttcaatcgtg atttctggca gccgtggacc attgaccagt gcataataca agctgctcat
    32761 gctaggctga ctagtattcc cactcattgc actcattgcc acgtcaacga tgtctactcc
    32821 tgcttttgaa gcagcagaat aagtgatgat tccattcccg ctggtatcat gagtatgcag
    32881 atggattggc agatctgtcg tttctttcaa ttcactaatc aaacgataag ctgcctgcgg
    32941 tttaagcagc ccagccatat ctttgattgc aatgatatgc gcacccagtt gttctagttc
    33001 ctttgccatg tctttataat actgaacatt gtattttgcc cgacttggat cgttgatatc
    33061 gccagtatag caaatagctg cctctgcgat tttaccagta tcccgtacag cttggatact
    33121 tttttccatt tgtggagtcc agttcaaact atcaaagatt cgaaatacat cgattccttg
    33181 cgctgctgct tctttgacaa attccaccaa tacattgtca ggataattag aatacccaac
    33241 ggcatttgaa cctctgaaaa gcatttgcag caacgtatta ggcattaaag aacgaatttt
    33301 tctcaaccgt tgccaaggat cttcattcaa aaagcggtaa gccacatcaa atgttgctcc
    33361 cccccacatc tcacttgaaa agagttcagg aagaccttct ccagtcaaac gtgcaatctg
    33421 cttgaaatcc tttgtccgaa cacgagttgc tagcagactt tgatgggcgt ctctaaatgt
    33481 cgtatccgtc aacaacaaat tttcctgtcc tttgatccat tcgaccaaag catcggcacc
    33541 cttcgcatct aatacattct tagccgttac gtaatcagtt cttgtgatta gatctttagg
    33601 catacgtggt tcttcataaa atggtttttc gccactttcg atacctggaa aaccattcac
    33661 agtaatttca ccgatatatt tcatcgtttt gtttccgcgg tctcgtagtc gaggaaattc
    33721 aaataatgtt gctgtactat caatgaaggt tgtttttgca tttcctgatt ggaattcagg
    33781 atgtgtgatg acattgagca taaatggaat gtttgttttc actccacgga ttctaaattc
    33841 tttcaagcaa cgttccattt tctgaatggc tgtttcaaag gtagcaccat gcgtacatac
    33901 ttttactagc aatgaatcaa aatacggtgt cactacatag cccgcgtaag catttccgac
    33961 atccagacgt acgccaaaac caccaggtga acgatacgta tcgattttcc ctgtgtctgg
    34021 taaaaagtta ttcaacgggt cttctgtagt gattcggcat tgaatggctg aaccatttaa
    34081 tttaattcct tcttgctgag gcaatccgat ttctttatgc agatccaaac cttgagcaat
    34141 caacagttgc gttgttacga tatcaatatc tgtaatcatt tctgtgatcg tatgttccac
    34201 ttggacgcga gggttgactt cgataaagta aaaatcatct ccttcaacaa gaaattctac
    34261 tgtacctgcg ttgacatacc cgacatattt catcaattgg acagctgcct ggcagatttt
    34321 ttgacgttgc tgttcattca tagagacaca aggcgctact tctactactt tttggtgacg
    34381 gcgctgaaca gaacaatctc tttcaaaaag atggatgacg tttccatgcg tatccccgag
    34441 aatctgtact tcgatatgct taggattagc gatgtatttt tcaacataca cttcatcact
    34501 accaaaggct gcttttgctt cgcttttcgc acgttcgtag ccctctcttg cactcttttc
    34561 atcgtgagct acacgcatgc cgcgtccgcc gccgcctaga gctgccttga tcataatcgg
    34621 ataaccgtat tgtttcgcaa actccaaggc atcgtctata gaagcgattg gtccatctgt
    34681 gcctggaatc gaagcaatcc ccgcttcgat agctgcagct tttgctttga ttttatctcc
    34741 aaaaatatct aaatgatgca gtttgggtcc aacaaaaatg atgccttctt cttcgcaccg
    34801 ttgcgcaaaa ttcaagtttt ccgacaaaag accgtaaccc ggatgaatag cgtcagctcc
    34861 gcattctttc gcgatagaaa tgatcccttc aatatctaga tacgcatcaa tcggtttttt
    34921 tccttgtcct actaaatatg cttcatccgc tttgaaacgg tgtacggaat attcatcttc
    34981 ttctgcatag attccaacag ttttaattcc taattctgta caagcacgaa atacacgtac
    35041 agcgatttca cccctgttag caactaaaac ttttttcatc gaaccactcc tacatctttt
    35101 tttattataa acctaagctc ttgcgttttt catccgcact gatgttgagg acaaagccga
    35161 cacaaatcga aagcatcagc aaactggagc ctccttgact taaaaatggg aacgtgatcc
    35221 ctgtcaaagg aataacgcca gtaattcctc caagattgac aaatacttgg atcaaaaaca
    35281 ttgcgccgat cccaatgcac aaaagcgaat tgaacggatc ttttgaacgg atacctacaa
    35341 ggacaatgcg cacaatcata aagaatagca acgctaatat caaaatcccc ataatcactc
    35401 ccagttcttc cactacgatt gcataaataa aatcggtttg tgcttcttgt aaaaatcctt
    35461 ttttctggat actgttacct aatcccctgc caaatagtcc tccgttgaac atggcatagt
    35521 agccgttgac tagttgatgc cctttattta attcgtctga gaaaggattt tggtaaatag
    35581 caaatcgatt atagatatac tgtaaacgtc cgggtaagat ctttccgttt gtgatattga
    35641 tcagccagat cgtaaaagta cttagacaaa agcctcctac tcctacaatc aaagtataca
    35701 cataattgac tccgctggct aaaagcagaa ccaaaataat caaaaagata actgccgcat
    35761 taccaaaatc gggaagaata gcgactaatg cagtaagtcc gataaccatt gcaagtggac
    35821 gtttcacagt cccaagaaaa tctttttgta cactgttttg tcttttagat aaagtcagag
    35881 acaggtacca gatagaaatg atttttaggt attcggcagg ttggatcgag aatcctgcaa
    35941 tttgcagcca acctttcgcc ccattgatct ccttaccaaa aaacacaaca atcagcagca
    36001 aaatcgtcaa aactgcgatg gctgccatga tcaaacgctg gtttttcaaa acatctgttt
    36061 tcattttata aagtagtgcg atagcaatca agctaagcac ccaaaaaata ctctggttaa
    36121 tgactgatgc ggacggattt tgtccgtttt ctaataatag atacgacgta gaactatata
    36181 ccatgatcaa tcccaataca cataaaatta aatagggaat caagatgcta tagtctaata
    36241 gatgcctttt tttcactttc ttaggcaagt ctattcctcc ttgccaactt cttttttatc
    36301 ataaatttct tggtaaacct cactatataa ctgattcaat tctcgttcta gctcacttaa
    36361 catcagctgg ccctcgttct ttccgattac tcctatacgg acagcaaaac cgacttgccg
    36421 ggaaaagccg tacatctgtg tatctaccac ttcttcgaag gctttgcatt gtgagataca
    36481 gagactgttg ttttgatttc ggattaatcg tttgatccgt tctgcttcat catttaatac
    36541 ttggatcgca agttttttcg acaaagaatc catctgtgct tacctcccat tctaattcct
    36601 taattataac atatttgatt ttcataagga gcaaaaaaaa cagatttaac cagttgtttt
    36661 tattcatttt tacgtattcg ttctttctac ttatccagaa cgttagagtc cgcatttttt
    36721 atccgagata aaaaggcttc gccatattta tcaagcttgc tttggccaac tccttttatc
    36781 tgaagcatct ccaatctgct tgatggacgt attcggctca tttctttcaa tgtggaatct
    36841 gaaaatacga catacggggg aacgcctgct tctgatgcta gatccgttcg cagttcccgc
    36901 agcacttcaa atagtgtatc ggtttcttca tccgatagct gctggacttt cttgggttcc
    36961 tttcgataaa cagattcttg tcctttcaat acttgtatcc ctctttctgt tactttcaaa
    37021 acaggatact caccattgat ggtcagaaga tagccattcg atatcaaata ttcaattaac
    37081 tgcatcgttt ctttttgcga ttggtttttc atcagtccat aggtagataa atgtccaaaa
    37141 cctaaagctt gcagcttttg ttctttcgat cctgctaaga ctttcatcag catttgttta
    37201 ccatagttct cacccatacg ttttaagcaa gaaagaacca tctgtgcttc tgtcgttact
    37261 tctactattt ctctgtcatc taaacagtta ccacaacggt tgcacggact gcttgtctcg
    37321 ccaaaatagt ttaggatgta ttgctgaaga caggactcaa tatacacgta ttctgtcatc
    37381 gcttttaatt tttcatattc tttttgcttt tgcccttctt ctctttggga ctgctggata
    37441 aaaaactttt ggacttggat atcttgagga gagaaaagca ggatggcttc actggaaaga
    37501 ccatctcttc ccgcccgacc agcttcctga tagtatgctt ctagagagcc aggaatttga
    37561 taatggataa caaaacggac attgctttta tttataccca taccaaatgc atttgtcgct
    37621 acaatcagct gcaagcgatc gtataaaaag gcttcttgca tttctgttcg ctcattctca
    37681 tttagaccac catgatatct acccacggaa aaatcgaatt ttttaagcaa atgatagaga
    37741 cggtctactt cttttctcgt tgctgcataa atgataccag attgattttt gttgatcttt
    37801 aaatattcga ttagatattg ttcttttttt tgatctttaa ttacttgaaa tcgtagattt
    37861 tctcgttcaa aaccagtctg aatatggttg ttttctggaa tttttaaaag tctttttatg
    37921 tcagcagcta cttgcacagt cgctgtagct gtcaaagcaa caattacagg acgatttggc
    37981 agttgatcta gctggttcgc catctgtaaa taacttgggc ggaaatcatg cccccactga
    38041 gagatacaat gtgcctcgtc aatagcgatc atacggacgt tccatcgctt cattgcttgg
    38101 ataaaatccg gcatgataaa acgttcagga gcgatataaa gtaaacggta ctgctgtcta
    38161 tcgatttctt ggaagcgtct agctgtttcg taaccatcta acgagctatt gataaaagtg
    38221 gcgggtatac ctaattgatt cgccgcgtcc acctgatcct tcatcaaaga gattaaaggg
    38281 gacacaacca cagtaagccc atctaatagt aaagctggaa gctggtaaca gattgatttc
    38341 ccacttccgg taggcatgat tcctaataca ttttcctgat caatgacttt ctggataatt
    38401 tctttttgac caggtctaaa ctcatcatag ccaaagtatt gttttaataa gtcgttcatc
    38461 ttcccgctcc tttctcttgc cattttactt cgattttctt cgaaggacaa gttgatctcc
    38521 tttcgtgaaa cattatctta ttatgaaaca aaaactctct agaaataagt tttttaaaag
    38581 tcttttaaac gcctttcggc gtattttctg aatttatgtc cattgacaaa gatgacttct
    38641 ccacagaaaa gagttggaca aaaaaagaaa ccagctattt tttataacaa gctggtttct
    38701 ctcttcatcc ttttacagat tattttttct ttttagatgc tttttcacga gcatttttct
    38761 ctaaaatttg ttttctcaag cgaatgcttt ctggtgttac ttcgcaatat tcatcatcat
    38821 tcaagaattc caaagattct tccaacgtca attgttttgg ttttttgatg acagatgttt
    38881 ggtctttagt agcagaccgt acgtttgtca tttgttttgc tttcgtgatg ttgacagtca
    38941 aatcattatc acggctgttt tccccgataa tcattccttc atatacttct gtacctggtt
    39001 ctacgaagac tgtaccgcgt tcttcgatac tcatgataga ataagtcgtt gcttttcctg
    39061 tatcgatcga aacaagcgcc ccttggtgac gtccgccaat ttgaccagga agcattggca
    39121 gatattggtc aaaagtatgg ttcatgattc cgtaaccacg tgtcattgaa aggaattcag
    39181 ttgaataacc aatcaaaccg cgggcaggtg ttaagaatgt caaacggatt tgtccgtttc
    39241 ctgtatggac catatcttgc atttcacctt tacgtaagct caaggactcg ataacactac
    39301 ccatatattc ttctggtgta tcgatttgca cgcgttcaaa cggttcgcat tttacaccgt
    39361 cgatttcttt ttcaataact tctggacgag atacttgcaa ttcgtatccc tcacggcgca
    39421 tgttttcaat caagatagac aaatgcaatt ctccacgacc agaaactgtc catgcatctg
    39481 gagagtttgt tggttcaact cgtaaggata catctgtttg aagttctgcc atcaaacgtt
    39541 cttcaatctt acgagcggtt acgaatttac cttctcgacc ggcaaatggt gaattattaa
    39601 ctaagaaagt catttgcaat gttggttcgt caatgtgaag gataggtaac gcatcttgat
    39661 gatccacagg agtaactgtt tcaccgacaa agatatcttc catacctgag acagcaatca
    39721 agtctccagc ttttgcttct tgaatctcta gacgttttag tccaaagaaa ccaaataatt
    39781 tcgttacacg gaatttctta actgttccgt ctaatttaat taatgctact tggtctccta
    39841 ctttgattgt tcctctaaat acacgtccga ttccgatacg acctacataa tcgttgtagt
    39901 caagtaatga aacttggaat tgtaatggtt cgtcgctgtt atcgacagga gcagggattt
    39961 tttcaataat tgtatcaaaa ataggtgcca tggttggttc ttgatctgct ggatcatctg
    40021 acaagcttga cgtaccattt agtgcagatg cataaatcac aggaaagtct aactgatcat
    40081 catctgctcc taattcgatg aatagttcaa gaacttcatc tacgacatgc tcaggacgag
    40141 cagaaggttt gtcaatcttg tttacgacaa cgattggtgt gatatgttgt tccagtgctt
    40201 ttttcaatac aaaacgtgtt tgaggcattg ttccttcata cgcatctacg accaacacaa
    40261 cgccgtcaac cattttcatg atccgttcta cttcgccacc gaagtccgcg tgtcctggag
    40321 tatccatgat gtttacgcga atacctttat agtctacagc tgtgtttttg gctaaaatcg
    40381 tgataccacg ttctttttct agcgcatttg agtccatcgc acgttcttgc aattgcgtat
    40441 gtgcgtctaa tgtatctgat tgttttaata gttcatcaac taatgttgtt tttccgtggt
    40501 caacgtgggc aataattgcg acgttacgga tatcgtttct ataattcaat gtaactaact
    40561 ccttttttat tggttcttta tgacagggca aattttactc gactgctaat tatagcagac
    40621 ttttttcatg aaatatagta aaatgttttc attttttcga gaaaattaat cttttgctcg
    40681 tttttatcat ttttgtgaat gatttctacc tttttttcag ccttcttttt tcaaaaggtc
    40741 tgcgatttct gcatatgcac aagaagtccc tgctaaatag tattcccttt tttcaaatgt
    40801 caaaggagta ccaaaaagac cgcttgttac cataccaaac tcttccaata agacatttcc
    40861 cgctgcataa tcccaagggc taaggtttga aatataagca atgtggtttc ctttcaagat
    40921 tgccactagt tcaagaccag cgcatccgta catacgtgtc cccatgctgc tttccgcaat
    40981 ttctcggatt ccatatttat tatgaccgaa aagataacta ttcacaccaa gtaagccttc
    41041 cgataaggat ttatttgctg gtctaggcaa tggctcatca tttttataca cgcctattcc
    41101 ttttccaccc caaaaaagtt catttctcat cacgtcataa atgaaaccaa gctttccaac
    41161 gccggattca taaacagcga gcataataca aaaattttcc ccttcaatca caaaattcaa
    41221 ggtgccatca ataggatcga tgataaagac tcttccatcg agatccgata attgattaca
    41281 cccttcttct tctgccaata ttttcgcctc tggatcaaag gaatggattt tttcgattag
    41341 aaaattctgg atgtttcgat cgacatttgt tactagatcc gttcgatttg atttttgcga
    41401 gattgttaat gtttgttgag aagatttgat tttctcacca gcttcttcaa gccaggactt
    41461 gatatgatca atcatctgtt ccatttatct cacccgttca ttctcaaagt tttgtttgga
    41521 ttttttttgc ttgctgcact gtacgatata aagaataacc ggaagctttt tcaaattccc
    41581 gtcccaatcg tttttcctca ccaatggatt tgacaacagt tttaaactgc tgataagtct
    41641 tcaaaaaagc ttcattgttt atcccttttt cattcgcacg ttccagatct tcccacatct
    41701 tcattacaat gaccatttcg tctgttgtcc aatctaaatc aagtggatac tgatattctt
    41761 gcatcttcaa ctctcctatt tcatattcct cttcagtgta gcataggaag tggtaataaa
    41821 ccaagaagtt gtcatatttt taagtttaca taataatatt attgataatt ctaaaaaaca
    41881 aaacgcaact gatttttcag ttgcgtttcg cctgtattat tcaaatcaaa tatggattgg
    41941 taaacctaat gctaattccg aagcatccat gacgatttcg ccaagagatg gatgaggatg
    42001 aatcgtcaag gcgatatctt cagcattcat tcctgattcg attgctaaag ctaattcaga
    42061 gaccatatca cttgcgccga ctccaccgat ttgcgcgcca ataagcacgt tatcttcgat
    42121 cgtcgtaact agacggatga atccttctgt tttaccaagc gataatgccc gaccgttccc
    42181 tgaaaatggg aatttatatg cttttgcttc gataccagca tcttttgctt ctttgatcgt
    42241 catacctaca gaagccaatt caggatcagt gaaggctact gccggcattg ctttataatc
    42301 tacagctact tttttgccag agattgcttc agcagcgatt tttgcttcat aactggcttt
    42361 gtgtgctaat gccgcccctg gaacgatatc accgatggca tagatgttag gtacgttcgt
    42421 acgtccttgt ttatccaccg tgatcaatcc tcgttctcct acttcgacac ccgcttgttc
    42481 taagcccata tcatctgtat tcggacgacg acctacagtg accatcacat aatcagcagt
    42541 aacggattct tctttcccgt ccactgcata tttcactgtc acgctgtcac cgttatcgac
    42601 tgcttctttc gccattgcat tcgttacgac tgttacgcct tttttcttga aatcatcttc
    42661 tactaatttt actagatctt tttcgtaagt tggtaaaatt tgtggtgagc cttcaagaat
    42721 cgttacttct gctcctaagt ttgcgtacgc tccgcccaat tcggcaccaa tcacaccgcc
    42781 accgatgatc acaaatttct taggtacttc tttcaatgct aatccgccag tagaatctaa
    42841 cacacgtcct ccgaatttaa atcctggaat ctcgattgga cgggaacctg ttgcgatgat
    42901 tgcgttattg aacgaataag tttgagctga atctggatga atgacgcgta gtgtgtgatc
    42961 atctacgaag aacgcttctc cttcgattgt ttcaacctta tgttttttta ataggaaacc
    43021 aacaccagaa gtcaacgtat ggacaacttt gttttctttc cattcttgtg tttttgcaaa
    43081 atctagtttg acgttttcac tagttactcc aaacatttca gaatctagtg actcttgata
    43141 atggtgtcct gcagctatca gtgcttttga aggaatacag ccgacattca aacaaacacc
    43201 gccaatatac tctctttcaa tgattgctac tttttgtccc atttcagcag cgcggatggc
    43261 agctacatag ccaccaggtc ccgcaccaat tacaactgta tctaattcta cagcaaaatc
    43321 tccaactacc atttgtttat catccttcca tcattaatag ctctggatca gctaaaagac
    43381 gtttgatatt attcattgct tgttgcgcag ttgctccatc tacgatacgg tgatcgaaac
    43441 ttaatgacag tttcatcaca cgaccgacaa cgatttcgcc ttcagcattt acgattggtt
    43501 gttgtgcaat cgttcctaca cctaaaatag ctacttctgg atagttgatg actggtgtaa
    43561 accaaccgcc acctacagat ccgatattgc tgatcgtaat tgttccattg cgcatatctt
    43621 ctgcagatag tttgccgtca tgagctaatt ttgctttctc attgatttcg tctgcaatag
    43681 caaacattcc tttgcggtct gcatctttca catttggtac atatagtccg tgatccgtat
    43741 cagttgcaat accgatattg tagtaatgtt tataaacgat ttcttggttt gcatcgtcga
    43801 tagatgcatt caatactggg tatttcttaa cagtcgctgt taaagctttc acgacatatg
    43861 gcaagaaagt aagtttcgta ccatttgcag cagcaacttc tttaaatcgt ttccgattat
    43921 cccatagttt agacacttct acttcatcat gcaatgtcac gtgtggagct gtatgcttac
    43981 tgttgaccat tgctttagcg atagctttac gtgttggcgt cattgctaca cgttcttcca
    44041 agtctcctaa gttggacttg aatggttttg ctggtgcagc tggtttgctt tctgctgcag
    44101 gagctgcttc tttcggtgct gccgcttctg gcgcttctga tttcgctggt gcactgcttg
    44161 gaccacctgc caagaagttt tcgatgtcct cttttgttac tctgccacct tttccagttg
    44221 cagttacttg tgagatatct acatcttttt cacgggcaaa ttgacgaaca gatggcatag
    44281 ccaatacacg tttatttgga tcggcagctt caacgacact tgctgaacct gatgtttcca
    44341 ctttttcttt tggtgcttca gctgatggcg cactagttga cggtgcacta ttgtgtccag
    44401 gagcatcgat ttctactaat acatccccaa catttgctac agtgccttct ggaacaatca
    44461 cgtttttaac tgtccctgtg acaggtgacg g
//
LOCUS       DAFEKH010000022        40827 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.023, whole genome shotgun sequence.
ACCESSION   DAFEKH010000022
VERSION     DAFEKH010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40827
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.023"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            35..658
                     /locus_tag="LP386_001310"
     CDS             35..658
                     /locus_tag="LP386_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918553.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1108..2157
                     /locus_tag="LP386_001311"
     CDS             1108..2157
                     /locus_tag="LP386_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL1918554.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2154..3035
                     /locus_tag="LP386_001312"
     CDS             2154..3035
                     /locus_tag="LP386_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1918555.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3038..3808
                     /locus_tag="LP386_001313"
     CDS             3038..3808
                     /locus_tag="LP386_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1918556.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4087..4941
                     /gene="aroE"
                     /locus_tag="LP386_001314"
     CDS             4087..4941
                     /gene="aroE"
                     /locus_tag="LP386_001314"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBL1918557.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5119..6282
                     /locus_tag="LP386_001315"
     CDS             5119..6282
                     /locus_tag="LP386_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBL1918558.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGGQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6399..6809
                     /locus_tag="LP386_001316"
     CDS             6399..6809
                     /locus_tag="LP386_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL1918559.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6983..9211
                     /gene="topB"
                     /locus_tag="LP386_001317"
     CDS             6983..9211
                     /gene="topB"
                     /locus_tag="LP386_001317"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBL1918560.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9382..9666
                     /locus_tag="LP386_001318"
     CDS             9382..9666
                     /locus_tag="LP386_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918561.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9826..10062
                     /locus_tag="LP386_001319"
     CDS             9826..10062
                     /locus_tag="LP386_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL1918562.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10059..10457
                     /locus_tag="LP386_001320"
     CDS             10059..10457
                     /locus_tag="LP386_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HBL1918563.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
     gene            complement(11124..12068)
                     /locus_tag="LP386_001321"
     CDS             complement(11124..12068)
                     /locus_tag="LP386_001321"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBL1918564.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(12364..13308)
                     /locus_tag="LP386_001322"
     CDS             complement(12364..13308)
                     /locus_tag="LP386_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1918565.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            13529..14743
                     /locus_tag="LP386_001323"
     CDS             13529..14743
                     /locus_tag="LP386_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL1918566.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            14765..16780
                     /locus_tag="LP386_001324"
     CDS             14765..16780
                     /locus_tag="LP386_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HBL1918567.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(16863..18236)
                     /locus_tag="LP386_001325"
     CDS             complement(16863..18236)
                     /locus_tag="LP386_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBL1918568.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(18262..18546)
                     /locus_tag="LP386_001326"
     CDS             complement(18262..18546)
                     /locus_tag="LP386_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1918569.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(18548..20563)
                     /locus_tag="LP386_001327"
     CDS             complement(18548..20563)
                     /locus_tag="LP386_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBL1918570.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(20742..21047)
                     /locus_tag="LP386_001328"
     CDS             complement(20742..21047)
                     /locus_tag="LP386_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HBL1918571.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(21136..22167)
                     /locus_tag="LP386_001329"
     CDS             complement(21136..22167)
                     /locus_tag="LP386_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL1918572.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            22374..23249
                     /locus_tag="LP386_001330"
     CDS             22374..23249
                     /locus_tag="LP386_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL1918573.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(23401..24243)
                     /locus_tag="LP386_001331"
     CDS             complement(23401..24243)
                     /locus_tag="LP386_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL1918574.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(24335..26212)
                     /locus_tag="LP386_001332"
     CDS             complement(24335..26212)
                     /locus_tag="LP386_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBL1918575.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(26209..27630)
                     /locus_tag="LP386_001333"
     CDS             complement(26209..27630)
                     /locus_tag="LP386_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBL1918576.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(27633..31022)
                     /locus_tag="LP386_001334"
     CDS             complement(27633..31022)
                     /locus_tag="LP386_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBL1918577.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            31279..32670
                     /locus_tag="LP386_001335"
     CDS             31279..32670
                     /locus_tag="LP386_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1918578.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSDYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(32743..33390)
                     /locus_tag="LP386_001336"
     CDS             complement(32743..33390)
                     /locus_tag="LP386_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBL1918579.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(33398..34084)
                     /locus_tag="LP386_001337"
     CDS             complement(33398..34084)
                     /locus_tag="LP386_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1918580.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(34090..35163)
                     /locus_tag="LP386_001338"
     CDS             complement(34090..35163)
                     /locus_tag="LP386_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1918581.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            35385..36059
                     /locus_tag="LP386_001339"
     CDS             35385..36059
                     /locus_tag="LP386_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1918582.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            36064..37404
                     /locus_tag="LP386_001340"
     CDS             36064..37404
                     /locus_tag="LP386_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL1918583.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(37553..38539)
                     /locus_tag="LP386_001341"
     CDS             complement(37553..38539)
                     /locus_tag="LP386_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HBL1918584.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            39263..40294
                     /locus_tag="LP386_001342"
     CDS             39263..40294
                     /locus_tag="LP386_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL1918585.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            40403..>40827
                     /locus_tag="LP386_001343"
     CDS             40403..>40827
                     /locus_tag="LP386_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HBL1918586.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIP"
BASE COUNT        12679 a         7414 c         7664 g        13070 t
ORIGIN      
        1 ataataaaaa ataggagaaa aagtagaaaa gaaggtgttt gttatttggg aagtagttaa
       61 atcgagagta caagaaatga atgaacattt ctcagtgtca ttcgcagaaa atccaagtaa
      121 gtattttcga cgtcttgttt ttctgctcat cttatcattg ctgttaacag ttgcaatgtt
      181 tttattgccg gaaaaaatcc gagaagagca agtaaatagt ctcgtttatt cgtccatacc
      241 aaccagcaaa ttgaaacctt ttgattacag caaagctgat cagaaaatca aacaaagccg
      301 ggcgatatcg gtgatgttca gcaaaccgaa cgggaaaacc tatcaggaca tgcttgatgt
      361 ttttaatgat cctgagctta tggaagaatt gaatcgaccg atcttttatt atccgatcgt
      421 ttatgatgta catgaactgg aacaaaaata taacatacga acggatgaag tgacatttat
      481 tttctttgat ggaggaaaag aagcaaatcg gataactgcg ggtaagggag gaataactga
      541 ttttgataag gagttgatcc ctgaactgaa tcgacttccg ttagccaata tcaaacaatt
      601 agaagaagaa ttggatagaa cgggagtaac ttcccaaaat tccgagattg ctaattgaga
      661 cattggcgcg atgaaacggt gggtctatat agcgctattt ttaattatca gaacaagtga
      721 tgtttgatct tcaaaataac aaataaaaaa ttaaaaaata tagttgacga aattcaaaaa
      781 ttcgattaga cttaaatcaa ttcttaagga aagggtgacc tgtaatgaac ttatcaaaac
      841 gtatttcagc agaaaacaaa aaaaattggc gcagctggcg tagataagtt gtattaatgg
      901 tgagactttc ccatagatac aactttttag agtgcatttc taaagcttgt atctatgcta
      961 gacatgaaca ttgactgccg catagattag aatctatgcg gttttttgtg taaagacaat
     1021 gaccgctttg gccattgtct ttttttgtag actggatact tgcctgatta taataaataa
     1081 aaagattgac tttgcaggag gaaaaaaatg aaaaacaaac gattaataac agttgtagta
     1141 attattttag tttatttagc aggtgcattt atttatggaa aagcctcagg cgaaaaagaa
     1201 agtacttcga cgaaccagac aaaaaaaaca acagttgttg gggtattgca atacgtgagc
     1261 catccggcat tagatgagat ttatcgagga atcaaagatg gtctgaaaga agaaggatta
     1321 aaagaaggag aaaatcttga gatcaaattt caaaatggac aagccgatca gagcaagcta
     1381 gccacaatga gtcaacagct agtacaatct gatccagatg ccttgattgg aatcgcaaca
     1441 cctgccgctc aatcattagc aaacacgact tcatcgatcc cagttgtgtt aggtgctgta
     1501 acggatcctg tgggggctgg attagtcgct tctttagaga aacctggtgg taatgtaaca
     1561 ggtgtttctg atcagccgcc tgttacttca caaatcaagc ttgcttctga tttgttgcca
     1621 aatgcaaaaa aagtcggaat cttgtatgct tcttcagagg ataattcaaa ataccaagta
     1681 gcacaagcag aagaagctgc aaaaaaagaa gggttagaat cagtaaaata tgcggtgcct
     1741 tccactaatg agattgcaca aacggttcaa gtgatgagcc gacaagtcga ttttatctat
     1801 gttccattag ataataccat tgccaatgcg atgcaaacag tggtaaaaga agcaaacaaa
     1861 gcaaatatcc ccgtcattcc atctgtggat acaatggtgg aacaaggtgg actagcaaca
     1921 atcgggatca atcaatatca attagggctt caaagcggta agatggcggc agaacttgcg
     1981 agtggaaaag aaaaaccgga aacgacgcct gtttatacat ttgatcaagg ggatacagtg
     2041 atcaatcaat ctcaagctga tcgcttagga atcattgttc cccaatcgat gaaggaaaaa
     2101 gccaaaatca ttacagatga ctcgcagcaa gaaacatcta aggaggatga caaatgatcg
     2161 tatcagctat ttcacaaggc atgctttggg caatattagg attagggatt ttcatgactt
     2221 atcggatctt agactttcct gatatgacga cagaagggtc cttcccatta ggtgctgctg
     2281 tctgtgtgac agctattact catggggtag cgccgattgt agctacatta ttaggcgtag
     2341 gtgctggcat gatagcagga ctcgttacgg ggttacttta tacaaaagga aagataccgg
     2401 ttattttagc agggatttta gtgatgtcag gattgaactc agttattttg tttgtgatgc
     2461 gaacaccaaa tctttcttta ttgaatcatc cgattctaca agacagcttc catcgctttg
     2521 ggttacctga ttactttgac acagtccttc ttggcttcat ctctttgggc atcttgattg
     2581 ctgtactgct attcttcttc aatacagatt tgggtcaagg ctatattgcg acaggagaca
     2641 acgaaacgat ggctcggtcg ttagggataa aaaccgatcg tatgaaaatt ttaggtttaa
     2701 ctttgtcgaa cggtgtcatt gcattatccg gtgcgctgat tgcccagaac gacggatatg
     2761 cagatgtaaa taaagggatt ggcgtaatcg tcatcggtct tgcttccatc atcatcggtg
     2821 aagtgatctt ccaagaattg acgctagcag aaagattgat tgctattgtt gtcggcagta
     2881 tcatttatca gctattgatt ttagtagtaa tcaaactagg gtttgacacg acttatctga
     2941 agttgttctc cgctatcatc ttagctattt gtctgatgat cccgcaattg aagaaagcac
     3001 tgaacttaaa aacgggtttt gagaaggagg catagtaatg actgatatat tgacaatcaa
     3061 aaatggcaga aaagtcgtaa acaatggaat gaatgaagag aaagtactat tggatgaaat
     3121 taaccttaca atcagagaag gggacttcat cactgtcctt ggcgggaatg gtgctggaaa
     3181 aagcacactg ttcaatacga tcgctggtac gcttcaactc agtcaaggat cgatctcttt
     3241 taaagatcag ctgatcacaa aagattcaga agaaaaaaga gcacgattcc tttctcgagt
     3301 tttccaagac cccaagatgg gaacggctcc tcggatgaca gtagcagaaa atttgctact
     3361 tgcacaaaaa agaggtcaaa aacggaaatt ccgtttacgt aacttgaaaa atcaaaaaga
     3421 agattttttc agactatgtc aagaagtcgg taatggccta gagcaacact tggatactcc
     3481 agcgggtgaa ttatctggtg gtcaacgcca agcattaagc ttgctgatgg cgacgatcac
     3541 agctcctgag ttactattat tagatgaaca tactgcagct ttagatccta aaacagctaa
     3601 agcattaatg cgattaacaa atcagcggat caatgaacaa aaattgactt gtctcatgat
     3661 cacgcatcga atggaagacg ccttgaaata cggaaatcgt ctgatcgtac tccaaaaagg
     3721 gaaaatcgtt caagatattt ctgaaaaaga aaagcaacat ttgacaatgg gcgacctttt
     3781 gcagttcttt gaagaagtag tggattgatt tcgacagaaa aattcctttc agtagaagga
     3841 cttgaaaact cattgacatc ttcctttgat tcatcctata cttaaaacaa taaacaatta
     3901 aacatatttg ggtgttttgt aggatcacgt agtcaatgat tttaacaatt aaatagaata
     3961 ttctttgctc tgacaagtaa acgatgagaa aagaatttgc tactttgcca cctagacgtt
     4021 tcgtactttt tcgtatcaaa cgctaagtgg ctttttttat tgaagtaaga acaaaggagg
     4081 aataagatga tttctggaca aaccaaatta gctgggctct ttgctgatcc ggcttctcac
     4141 agtttatccc cattgatgca caatactgct tttgaagcaa acaacatcga tgcggtgtat
     4201 ttagctttcc aagtaaatcc aatgaatttg aagcaagcag tcgaaagtat tcgaactttt
     4261 gatatgttag gtgtaaatct ttcgatgccg aataaaacag cggttattcc ttatctggat
     4321 gaggtaagcc aggaagcgca attgatcgga gcagtgaata cgatcgtgca cgaaaagggt
     4381 cgtttgattg gctataatac tgatggtgcg ggcttcatgc aatccgtgca agaagctggg
     4441 atttcgatca aaaagaaaaa aatgactcta ctgggagctg gaggtgcagc aaaggcagtc
     4501 actgttcaag cagcgttaga cggcgctgag gaaatcgtag tttataaacg aaacaaccaa
     4561 acattcgctc aagtaaaaga aacattcgaa caactcagct atcgaacttc ttgtaagata
     4621 aaagttcgtg actttgccga tacgcatcaa ttaagaaaag acttgaaaga aagctgtctt
     4681 ctagtcaatg caacagatat cgggatggga aagaaaatca atcagtcacc gctcttagat
     4741 ataagcatga tgcatgagaa tctagcggtt tttgatttga tttatgcacc tagagaaaca
     4801 cgtttattaa aagaagcaaa aaaagtagga gcaaaaggat acaatggact tggcatgttg
     4861 atctaccaag gagcaatcgc gtttgaatta tggacaaagg aaaagatgcc gatccatgtg
     4921 attgaaaagc tgtttgatta aaaaaggata atagataaag atcttttatt ctcgcataaa
     4981 cggtctcaag aaaagtaatc ctttatgtat cgaagcattt atttcgttat tttttattaa
     5041 attatcaaaa aatgataggc ttttgtcgat tggttatcgt atcctttatt tatcagtaag
     5101 aaacgaggag gaaccacaat gagtcggatg gatcgctata aggacatcca taagaaggcg
     5161 aaacctctga agcgggatac ggggagtatt tttgctagaa gagaacgaaa acgaacgcgt
     5221 atggaaaatg aggaagatgc tacccgtatt tatgaaagag agcagcattc atttgaacat
     5281 ttgaaccaat acgagcaaca gatatacaga gatgcaccaa gagcagaaga acaacaaaaa
     5341 aataaaaaat ttttcaatcg gcaaaagaag aacaaaccgt taaaacctcg aagaaagcga
     5401 tcgtggaaaa aaatcattct atcgattttg cttgttttga tcctttattc aggtatctca
     5461 ttttttattg gtaaatatgt agctgaacat gacacaagct tagaggcagc gacttcagaa
     5521 acctttcatg ggcaaaaagc gacgaatggt gcgcataata ttttgatcct tggaagtgat
     5581 acacgcggag aagatgccgg gcgagccgat acgatcatgg tcttacagtt ggatggtcct
     5641 tcccataagc cgaaactgat ttcttttatg cgtgacagct tcgttacgat cccaggggta
     5701 ggacaaaata agatcaattc agcttatgca tacggaggag ccgatctagt gcgtcaaact
     5761 ttagtagaaa attttggaat cgattgtcaa tactatgcga aagtcgattt caaatcgttt
     5821 gaaaaagtga tcgatgcctt attcatgaac ggagtgaaga tcgatgcaga aaaagatctg
     5881 aatctggatg gtgtagatat taaaaaaggg ggccagaaga tggatggaca tgttcttttg
     5941 cagtacgcac gtttccgaat ggatgaacaa ggagactttg gccgtgtcag acgccaacag
     6001 caagtaatga acgctatttt cagccaattg aagaatccat tgaatctgat ccgtgcacct
     6061 tatgcagctg gtaaagcttt aggatataca tccacagatg tcactgcttg gttcttgacg
     6121 aaaaacctct tttcgattgc acgaggagct ggtggcattg atcgaataag tgtgccagta
     6181 gacggttcgt ggaattatgg gcaaagtgat tatgctggca gtattcttga aattgataat
     6241 caaatgaatc aatctgctat tacagatttt ttgaataaat gatcataaaa aagatcaaga
     6301 agaagctgcg caaggctttt gtcatgaatc aatcaaacga ttcactcgta aaaaacgctt
     6361 tcttatggta gatttaacca agagaggagc tgtttacatt ggatatctat ctgaacttca
     6421 aaaatgagtc gcgtgaagcc atcgcttttt atgaaaaagt ttttcagact gaagcatcag
     6481 gtatcaccac atacggtgaa atgcctggaa tagaacaaat gaacttgcca gaagaagcaa
     6541 aaaatctaat cacgaatgca cggctgaaca tttatgatac attagttatg tttgcagata
     6601 cgccagaagg aattggtcct gaattagttg tgggaaataa tgtttcttta gtcatccaga
     6661 caagaaatga agaagaaacg aagcgcctat ttgaaagctt agctgagggt ggtaagattg
     6721 agatgccact ggatgctgtt ccgtgggctc agttgtatgg gatggtaact gatcgatttg
     6781 gcatcaactg gcagattaac caagagtgac agctaaagat gaatattttc tggaaacatc
     6841 aagcagcaaa cggatcatcg tttgtttgct tgatgttttt gtgtctattt cgactatacg
     6901 gtatcttttt tttattgcca gatgcgaaaa tatgttccat aatagagaag tccgcaaaaa
     6961 attaagtaac ggaggtcaga agatgaagac ggtgatacta gctgaaaaac cttcacaagc
     7021 aaaagcctat gccgaaacct tccaacagca aaagcggcat gaagggtatt atgaaatcag
     7081 cgatccattg tttgctggtg aagtaaccat cacttatggt tttggacatt tggtagatat
     7141 ggttgctcca ggagcttatg aagagcgttg ggcaaaatgg tctttagaaa atttgcctat
     7201 tttcccagaa accttccgtt acgaagttcc aatggacaaa cgtgcacaat tttcgatcgt
     7261 aaaacgagaa ttgcagtcag ccgataccat cattattgca acagatggtg atcgagaagg
     7321 tgaagccatc gcgtggtcga ttattcgaca agcaaacgca ttttctaagg aaaagaacta
     7381 tttacgttta tggatcaatt ctcttgaaaa agaagcaatc tatgaaggtt ttaagaatct
     7441 ccaacctgga aagaactatt ttccaaaata taaagaagcg caagcaaggc agaacgctga
     7501 ttggctgatt ggaatgaatg gaagtccatt atatagcttg ctacttcaac gaaaagggat
     7561 tgatggcagt ttttctcttg gtcgtgtaca aacaccgaca ctctatatga tttatcagct
     7621 gcaagaagaa atcaaacact tcaaaaaaga aacgtacttt gaaggagaag gtttaattac
     7681 gacaaacaaa gggcagtttt ctggaaaaat cgtaccaaaa aaagcattta aaacccaaga
     7741 agagttaacg aaggaaatag aaaaacttgg agcgcattta ggtaagcaaa acggacggat
     7801 tcttgaagtt acgaaaaagg aaaagaggtt gcatagtcca cgtttatttt cgctatctag
     7861 tttgcagaca aagatgaatc agctaatgaa agcaagtgcc aaagctacac ttgatgctgc
     7921 tcaaggattg tacgaaagca agtttctaag ctatccaaga acggattcct tttacattac
     7981 agaaaatgag catcagtatc tggttaaaca tctgcaaaat tataaaaaat ttttaggaat
     8041 agaagaagta cagacaactg agatcaaagc aaagaaacga tatgtcgatg cgaaaaaagt
     8101 tcaagaacat catgcaatta ttccgacaaa gacgattccg actcctgcac gctttgcgaa
     8161 gctttccaaa ttacagcaag caatctattt gcaagttttg cgcactactg tggctatgtt
     8221 tgctgcagat tatatctacg aagagacgac cgtaatgacg ggcgtacagc aattaaagct
     8281 aaaaagcatc ggaaagatcc cattacagca aggttggcag gaaatcttac gcatcaagtc
     8341 aaaaaagaaa gaagctcaga ctcttcctcc tatcgtagaa aatgaagaag cagaagtaga
     8401 actgaaaagt atggagaaag aaacacaacc tccaaaaccc tataccgaag gaacgttgat
     8461 cacagcaatg aaaactgcgg gaaaaacgct ggataatgat gaagcgcaag aaattctcaa
     8521 agaagtagaa ggaataggga cagaagctac acgagccaat atcattgaaa atcttaagca
     8581 gaagcattac atcgaagtca ataaaaacga aataactgtt acgccaaaag gaatcactct
     8641 ttgtaaggca gtagccaatg aaccattact gacgagcgca gaaatgactg cgcgctggga
     8701 agggtacttg agaaaaattg gtaaacaaga ggggacacca tctgtttttt tagagaatat
     8761 caaaaaattc atcctacatt tattggcaga agttcctaat caaatcgaca aggtagactt
     8821 ttcagatgag attagcggga cacgtcagat aaaagcgatg gagaagaaaa acgatcaatt
     8881 aggaagatgt ccaaaatgta aaaagggaat agtcatgctt tatcctaaaa tcgctacatg
     8941 cttgaatccg gaatgcgact tcaaattgtg gccaacagta gctaaaaaga agctgactaa
     9001 aacgaatctc agagatttgc tttcaaaagg aaagacaagt aaagttgtca aaggttttac
     9061 tggtaaaaaa gggaaattcg atgcagtttt agtattaaaa gaagatatga caatcggttt
     9121 ttcttttcca tggatcgaaa acagtggaac aaaagcagtt gatggaaaca aagaaacatc
     9181 aagaaaaaat aatgaaaacg aagtagagta aatgaaaaca atgaaatagc ggaatattta
     9241 ttccgaaaag tgagaatata aataccaata aaactaaaaa atatcagtga atcaagcaaa
     9301 aacgttgggg taggctgatt ttatatagat agcaaggagt ttttttattt gaaaaaagtg
     9361 cattcatttt taaattatct tatgggagca atcacgattg tggctgtgta ccaagcattt
     9421 ctaaagtatc ctgattacgg gacgaagttg ttgtcattga cgcacaatca aacagcatat
     9481 tcaccaacgt tgattttatc gactttgact gcaggagcta aaagcgctac ttattttttt
     9541 cataaaacga caagcatgct aaagcgaaag aaacagcgaa aacaattgtt ggtggtggta
     9601 gcggctatga tcattattta ttttctacca gttattacac aagtatttca tcaatatttt
     9661 ggttaagaat acgagagttt gtgacaaaag tcatgtcaca aacttttttc tttgtcattt
     9721 tttcgtaaga aaaagcaaaa taaaagtata tacattgatt aaaagtatat acttggatat
     9781 aatgtactta ctatagaatg agaatggtat agagggtggc gaaatatgaa aaaaatgaaa
     9841 aagtataaaa ttagaaaatc tggcaatagc gatgtaacaa ctatcccacc agaagtaaaa
     9901 gaattcatgg gtgtgcagac aggtgacgca atcagttatg tttttcaatc tgatggttct
     9961 gtacgaatga tcaaagcaca agaagaacct gatattgatt cattagttga ttcgatcatg
    10021 aatcaatatg aagacgcgtt aaaagatttg gttgatttat gaggtatctt tcgactaaag
    10081 aaattatcaa aatcaacgcg aaagttattt tacgtcactc gccaggcgaa atgatcggtg
    10141 taaaagatgc aaatgcatta gatatggccg tcaaacagcc ttcacaagca gtattcaatc
    10201 aagaactcta tcctgaaatc tatgaaaaag cggcgatttt agcaattaat ttagctaaaa
    10261 aacatccttt tcataatggc aataaacgaa ctgctcttgt tgccatgttg ttgtttcttc
    10321 aattgaataa ttgtccagtt gctttttctc gtcaagaagc tgttgatttt atcataatga
    10381 ttaccactag ttcattggat ttcgattcac taaagtccaa gataaccagt tatttacgac
    10441 aaaccgcaat aaaatgaacg aattaaaaac tttatttctc aattagatca gcatgtcatt
    10501 aaggaatatg ctgatttttt tatgtttaat catacaaaat agttttttca taaaaatatg
    10561 gaaaatatgg attaattttg aaataattga tttaaaagga atacaaaaga gtgaatagta
    10621 ggaaatagtg gtttagaact agtgggctga ttttttatat attttagttt acataatata
    10681 tattatacaa agtagattta aaaaatgata aacctctctc gaacggtttt ttatcaaaaa
    10741 tcgtcatttt tccatcaaaa tctgcttatg caaaattata aaaaaatttt gcagtttttc
    10801 ttactttttt tgtcgtttaa ttgaatgata aaaaccagtt tctttattca gttaatcaaa
    10861 tatgaacgaa ttagatatga atcattgtat ttgccgttgc ggaaggattt tttaattaac
    10921 cacagataaa cattgataac gattcgctta ttgtaatcaa cagattaaat ttcatatgtt
    10981 catatgtacg gatacatttt cggaccgatt aattttaacc attctgttta tttgcttacc
    11041 tattagatat caataaaaaa ctgcttaaca gctatttcag ctgttaagca gttttaggat
    11101 ttttagttca tattcattgt ttcttataat acagtgttca atacttctct taaagcactt
    11161 gttgatttgc tgaacattgc tttttcttct tcgttgattg ataattcaac aacttcacga
    11221 acaccatttt cgtcaacgat tgatggcaca cctgtaaaga tatctttttc gtcgtattca
    11281 ccagttaaat aagcagatac aggcaataca gcttgttcgt tattcaagat agcttttacg
    11341 atacgtgcag tactcatacc aataccatag taagttgctt ttttacgatc aatgatctca
    11401 taagcagcat tacggacttt atcagcaatc acatctaatt catcttgggc aatacgatgg
    11461 tctttttcta caatttcaaa cactggttta ccaccgacag ttgtatgtga ccatgcagca
    11521 acttctgaat caccatgttc acctaagata tagccgtgga cgctgcgtgg gtcaactttt
    11581 aatttcaatg cgatttcttt acggaaacga gttgtatcca atgttgttcc agtaccgata
    11641 acacgtgatg ttggcagacc agattcgttc caagcgatat atgtcaaaat atctactggg
    11701 tttgaagcaa caacgataat accgtcgaat cctgatccca tgatttcttt tacgatttgg
    11761 cgcatgattg acgcatttgt tttaactaaa tctaaacgag attgaccagg tttttggttg
    11821 ataccagctg tgataacaac gatatcagca tctttacatt cttcatagcc acctgaccat
    11881 acagccacat tttcatcgcc ccaagccata ccatctaaaa ggtccaatgc ttccccttct
    11941 gctttttctt gattcacatc gatcaatact aattcattag agattccttg gttgatcatt
    12001 gcataagcga tacttgttcc aacaaaacct gtaccgacga ttactacttt acgacttgtt
    12061 tttttcatga ataaacagct ccttttcata actatttgtt actttcatga aaagtatagt
    12121 cttgtttatt cattttatca acatgttaat tataatagtt gttattataa tttttgatgg
    12181 aaacgaattc ctgaatacgc ataacagata aatgacaaat gtttacacct atatcccctg
    12241 ataatacaac caaaagttta gaactgaaaa taaatccaaa aaaattcgct gcaacgatat
    12301 aataagacag caatcgcacc taaaacaatt ttccttcata tgctttagtg aaagattttc
    12361 ttcttaatgt ttatttctcc attcattggg agtacatgtt gaatacttct tgaataattt
    12421 gaataaagaa gtcgtttgtt tatatccgat acgattagcg atttcttcca acgaaaaact
    12481 cgtttcttga atcagttcca acgcaaagtc gaattttttc tttagaacca gttcttgaaa
    12541 ggaagcatca aaatacattt tcaatttatt actaagatag accggattgt agccaaaatg
    12601 agctgctgtt tcttttaacg tacaagaagt aaaatgctta tcgatataat ctaatactct
    12661 aagcatctca ttttctgcgc atccatctgc tgatgaaaag ctttgttgtt ctaataaatg
    12721 agtcaattcg atcagtaata gtgatgtata gagatttaac gaacggatct tatgactgta
    12781 tgtatcaaaa taaatcaaca gcatattttc aatcaaatgc gtcaaacgac ttgtttttcc
    12841 gccgcgaaaa tgaatgaatt gtgtatgttc ccctttttct tttgatgcat ttatcaaaaa
    12901 agaagaaagt agattatttg tgcttgccaa atgattcaat atctctgtag ataaggtttc
    12961 ttcttttaat aagatgttga ttaaaatatc ctcttgccct gtgtattcga ttctttgagt
    13021 agcttcttta tcaatgatca ccacgtcact ttcttccatc tctatccttt ctccattaat
    13081 aatttgtaaa catgtaccgc tatacatata attgatttca acaaaatcat gtgtatgctc
    13141 gggaacttcc gcatatcgac ggtgtttact gatatgaata tttccctgtt gaaatagatc
    13201 ccctcggtgg atttttggcg gtgtctgaag atggtaagct aagtttaaat cattgatatt
    13261 cattccttgt tcacgctgca gagtttcgat tgattcttcg ttacgcaaaa aaaatgtcta
    13321 attcagctag ttccaattga ctccctcctt tttgtaagcg gtttctttcg cttattagtt
    13381 cacgctgtac tgctattata tgcaaagcta tttttggttt cataaagact ttctatggtt
    13441 gggacatgaa cttcctgtga ttccgctatt gagagaataa ccacttcata ctatattttt
    13501 gataagcgct tacaaaaatg aaaggaacat gcttatgaat aaaaagatga tgaaattttc
    13561 tctgctgtca gtctctctta ttttgacttc tgctggtgca gtcacgtctg caattcccag
    13621 tatgtcagct acttatgcca cgcgttcttt atctgctgtt gaattattaa cgactgctcc
    13681 ctcttttatg gtcactattt ttgttttgat tagtagtttt attgctagga aaatcggaca
    13741 aaaacaaact gtgatcatcg gattagtgat tgcatcgatt tgtggtatcc tccccctctt
    13801 ctcacaaagt tacagtattg tcttagcttc aagagctgga ctaggtattg gctttggatt
    13861 gatcaattct ttggcagtca gcatgattgc tgccttttat cacggagatg aacgagcctc
    13921 tatgattggt tttcaaagtg catttcaagg atttggtgca gctttaatga catttgttgc
    13981 aggacagcta gtacagttcg gttggcaata taccttttta gtctacgcca tcagcttacc
    14041 tattcttgtc ttgtttgttt tgtttgttcc tacacctgaa acaactgaac ttcaatcgca
    14101 tggcacagcc ccaacaagac aagtaatcaa aacgaatcct aaaatgatta gttatggtat
    14161 ttttctcttg ctggtcatcg tggtatataa tgctgtatcg attaaattag ccacagtcct
    14221 gacgacttat tctctaggaa acgaaactaa tgcagcgaat atcttaacaa tcatgcaatt
    14281 ggcaagtatg gctgccggag tttgttttgg ctggcttcag acaaaagcac atcgctatat
    14341 gcttacactt tctttactac tgatgggaat cggctttgta ttgattgcca ctgtgataaa
    14401 cctgtatgtg attgggtttg gtgcgatcct aacaggaatt tctttttcgt tattcattcc
    14461 ttacttattc aaccaagtaa gtatccaagc gcccaagtac gcggagagtt tcaatacttc
    14521 aatcttattg gttggcgcta atttaggtac tttcattgca ccatatggtt tgctctttct
    14581 ctcttttgct tctcttggga gtaaaacact tgctgttttc gtcaatggca gtatcttgct
    14641 gttgattagc gcgcttatta gccttctagt agtacacagg acgaatagaa agacagtgat
    14701 aagagtagat gaagaaataa aagaacaatt gacaacaaaa taaatttgat ggaggtcgtg
    14761 taaaatgaca aatgaaaaac ataaagatag atggctttgg tatcctggag actttgagat
    14821 ccgccatgga ctgctacaaa atttccaacg ggaagaacga ggttttgact ggccagcgta
    14881 ctggtacatg gatgattgcc atcggaacgt caagtttaag agatattact ttcttgatca
    14941 accttccatg tttaaagtga cgatccaagg agttgggtat gtagaaatta atggacaaaa
    15001 acatccatgt ggaaaatggc tgacttgtcc agctggtaaa gcaaaaattc gtatctttgt
    15061 aggacataca tcagggctac cagcgatgtt tatcgaggga gacgaagtaa aatcagatat
    15121 tggctggaca gcaagtaatt ttattgaaga atatccagct ggctggagtc cgctttatgt
    15181 cgatatcgca aaagatccaa atcaaatcta ttatcaaaaa gaatgcgtcc atccagtcac
    15241 tgaaacggag attggcggag gaatcttatt cgattttggg cgagcagtga atggctgtgt
    15301 agaactaata tctctggatg accatatcga atctatcact ctatgttatg gagagtccga
    15361 tgtagaagct atggatatcg attattgcta ctataagcaa ataggaatga caagaaaaat
    15421 gaaagctcgt aaacgcgctt ttcgctattt gtttatacca gaggtttcta ctggaatggt
    15481 tcaacttcaa gtttttcatg aatttttatc tctttcgaaa caagctgctt tttcaagcga
    15541 ttcttcttta ctgaatcaga tctggtcagt atcagaagaa gccttcaagt tatgtagtga
    15601 tttgtttttt atcgacggta tcaaacgaga tcgctggatt tggtctggag atgcgtatca
    15661 atcattcatg atcaatcaat atcttttttt tgacgaggaa atcaataaac gaacgatatt
    15721 agcattaaga ggacaaaatg aaatcaagca gcatatgaat actatcgttg actattcgat
    15781 cttgtggttg attggtatcg aaaaccacta tatgatgacg aaagactatg aatttttacg
    15841 catcgtctac cctaagatgc aatcattaat gagatacttg atggagcaaa cgaatgaatt
    15901 agggtttatt tatgggagag caaaagattg gatatttatt gattggtctg aaatggataa
    15961 agaaggaacg cttgctgcag aacaagtctt attactgaaa gcctatcatt ccatgatcac
    16021 ttgcggagat atcttagctg aaacatatgg agagaacgaa aattatcata ctcatctcta
    16081 tcaagaaaaa tatcaactat tgaaacaaaa cctatttgac tacttttggg atgaagaact
    16141 tggcgctttt atcgattgct atgaatctgg gagaagaaat gtgacgcgtc atgcgaatat
    16201 tttcgctgtt ttattcgatt ttgctaacaa agaccaacag caatcgatct taaagaatgt
    16261 cttattgaat gacactatca cacagattac tactccatat ttcaaattct atgaacaaga
    16321 tgctttatgc aaactcggac agacgaatat cgtctaccaa acgattcttg attattgggg
    16381 agggatgtta tctcatgatg cggtaacttt ctgggaagaa tacgacccta ctcaaacagg
    16441 aaatgaaaag tacagtatgt atggagatcc ttatggaaaa agcttatgcc atgcatgggg
    16501 agcaagccca atctatcttt taggacgcta ttttatcggt ttgtatccaa caaagccagg
    16561 ttatgaagaa tttatgatac aacctaatct agattcattt gaaacactga attgtacgct
    16621 acctatcaaa gatggaaaga tttcgcttga aaaaacaaaa gataagatcg tgattacttc
    16681 tgatagaaca ggcggaacag tgaaaatgaa tggtaaaagt tatcctcttc tagcaaaaca
    16741 gccacttgtc ttaacaagct attcaaaaat aaatgcataa aacaaaaaac tgcttgcgac
    16801 atatcagaag actttaaatc ttcttctgat attgtccaag caatttttat tttgaagttt
    16861 gcttaattct gttctttaga aacaatgttt gttctttttc cggcaaaaag aaagctagat
    16921 aatacgacaa gtaaaaagaa agcgatgatt ccaactgtca aggctatttg accgtattct
    16981 cctagtttcc caagtacaag tcctggtact agataatcag tatcggcaaa tgtagaagaa
    17041 gcgattttaa gatctcctaa tactggaagg ataaataatg gcagccaact aatcaataag
    17101 ctattgaaag cagaacctaa taccgcccct cttctaccgc cagtcgagtt gccgaagaca
    17161 ccagaagcag ctccgcagaa gaaatgtcct actaccccag gaatgataac tgtagtttgc
    17221 aagcctatca tagcaaacat ggatagtgtt cctacaaaga agctaacaaa aaagccaatt
    17281 aatacagcat taggtgcata tggaaaaacg ataggaacat ctaatgctgg tttagaatcg
    17341 ggtacgagtt ttttagcaat cccttggaat gctggaacga tttctgccaa caccattcga
    17401 accccttgaa ggacgataac aaacccagct gtgaatgttc cagcttggat cagtgcaaag
    17461 attacagcgt tgtctccatt gcttagttct ctttcaacaa atccaggacc agctaacaaa
    17521 gcaagtgcga catatacgat cgacatcaag agcatgatcg atacagtaga atctcgcaaa
    17581 aagctgaaac ttttaggaat ctttatgtcc tctgtagaac ggtctttgtt tccaaaaaac
    17641 tttccgatcc atccactaga agcataaccg atatttccgg tatgccctaa cgcaacttga
    17701 ttgtttccag tgatgttctt cataaacggt tgacaaagag caggcgtaat agttaatagt
    17761 gttccttcga agaccccgcc taataagatc atccacaaat ttgcagtaaa ccccgcgctt
    17821 actaaaatga ctgctgttag acaagaaaca taaagcattg cttgacctgt aagaaaaatg
    17881 aatttatatc ttgtgaatct agcaagtaaa atattcacga tcatccctac tagcatgatc
    17941 aaagcagtag gtgtaccgta ttgttgcaaa gcaatcgcca ctactgcttc attgctagga
    18001 actactcctt gagtatgcag agctgtttgg aacatcgaag caaaaggggt tagtgaatta
    18061 ctgattaaac cagcaccgcc gatcagtact aggaatccga caaatgtttt gatagttcct
    18121 tggatcactt ctgaaaattt cttcttctga agaacgagac caagcagtgc aatcaaagaa
    18181 acgaggatgg agggctgact gacgattgac acaaacaaat tcaacaattt atccattgat
    18241 agttcctccc ttgaatcatt tttattcttt tgacaagatc ttcgttactt tttcttttac
    18301 ttcttcgctg tcaatgatcg attgcaaagg tacgagcttt tcatcaggta tagaagttag
    18361 cgtatctttc aaagaatgct caatgaagaa ataatcagcc atatcgctag atacacttcc
    18421 aacatccgta tgacttactt caaactcgtc cacatctgct ccaagatctg caagtgcttg
    18481 tttgatgttc atctctacca taaaacttgt tcctaatcca ctttgacata ctgcaaaaat
    18541 tttcatatca ttcgtctcct tttcttatga tcgctaatat ttcttctttt gttgatgcgt
    18601 gtaataaatc ttgaagattt tgtttattag aaagtagctt tgttaaattt gccaaagccc
    18661 gaagatgtgc ctcattatcg atagcagcta aacagatgaa caaactaatg ggatgggctg
    18721 gattatcaag cagatccaca ggttgttgaa gtttcagcaa agacatccct acttcgttta
    18781 cgccatcttc tggacgagca tgaggtaatg cgatgtgatc gccaatatgg ataaacgcac
    18841 catactgctc cacgcgctcg atcatagctt tgatataact ttcttctatt ttattttctg
    18901 ataatagcgg ctgtgcggca aatgtgattg cttcttgcca gttttttggt tgatccgata
    18961 attggatcat ttcttctgtt aataattcag atagcatagg acgttgatcc tccttctttt
    19021 ctaaaagttt gttcatttta cgatttaata cttgatagag cttttcttcg tctacgcctt
    19081 cttttaattc gatataaggc agtagcgccg acaacaattc ttgggcagaa ggcattgaaa
    19141 atcctggtat cagccaatct ctttgtactt gattgatcag ctgatttttt tccaagtcag
    19201 tcatgattgg atgcagaaca tagagagact ttttcttatc agtaagtgtg agaggtacag
    19261 tagaaaaaat aatatcgtaa gaagtttcgt caacctcgtg taagcggtca gctgaattag
    19321 tctctgtaaa aaagatcatc gggaataatt gctgaagttc actttttaag atcaatgaag
    19381 agctaatgcc acttggacag acgatcacgg ctcttatttt tctatttctt tcttctgcgt
    19441 ccgcttttct gatctctccg ccaaatagta tagtgaaaaa accaatctct tcttcaggga
    19501 tgctcttccc tattcgtctt tctaacggaa gtaatgcttt tcttgtcatt tcgtagatgg
    19561 aagcatattg atgcttaatt tgatcgatca tcacattagg taaataaaaa gaataggaaa
    19621 tacgaaaata ggcagggacc aagtgataaa agacattcat caataattca cgaaacgaag
    19681 caaattctac ggccatcagg aattccatgc gatggatgac ttctgaagaa cattccagca
    19741 aaaaatcaag tgcaggctcc tggacatctc cttcaacgat cgatgctaag caaagagaga
    19801 aaaatataat ctccgaattt tgatgttcgg aatagccaag gccagtcaat acttgtcgac
    19861 taatgtcagt gactgcaaga gaagccaaca gttcagcatc ttttaccagt tccatggatg
    19921 tttttccaat tcgaatggtt gtcaaactca aataataagc taattcatcc attcgatttg
    19981 gtgcgaatcg aagatctgat agtgaaatcg ttttatctag caaatctcta actttggcgt
    20041 aataatcaat ggaaagggtt gcggttaaat acgtgagccc aaatcttcca gcaagtgact
    20101 gcatcaaacg agcagtgcga ttttttgctt ctcttcttaa tattgcttct gaccctagca
    20161 gcctaaaacc agttttccta gtatacgaca gctgacaatc ttccacttct aattcatttc
    20221 ttatcttttt gatatctgac aggactgtcc ctttagaaac ctgaagaaaa tcttgaaaat
    20281 gaaaaacaga aacagacgtt gcagtcgaat aaaccatcaa ataaagaaga tctcttcgct
    20341 cttgttcggt atacacagct tcaaatcgag taatatccaa aaatttttct gcccagtcga
    20401 ttgctcggaa tttctttata cggatacggg tatcatccac atattcggca aaaggagtta
    20461 attgtttgat cgcctcgctt gtatttactt cgatgatctc tgctgctttt tctagactga
    20521 tttctcttgg tgttttcagg agataactaa ttttgtagtt cacagcgctg ttcacctcct
    20581 acttatattc tagtatggta gcgcttttaa atcgaggggt gtttggtaca acttacagtt
    20641 ggattttttt tacgactgta ccgaacgatt tctatcgaat ggatacagaa aaaaagcagg
    20701 tgaccaaatg tctcctgctt ttatgaattg atttcgtccg atcaatgatg atcatgttta
    20761 ttttttgagg tcagttcttc aaatttttct ttgacatctt caaccgcttt ttcgatatct
    20821 ttttcaaagt gattgggctc attaggcttt gtttcctctt ctacagaatt tgaaccagat
    20881 aaagctgttt ctttattttc tgtttcacca gagtttgtgc cagctaatga ttcttctttg
    20941 tcttctgttt caccagaatt agttcctgct aaagccactt cttcttctgt tttaggggcc
    21001 attgaacctc ttaatcgttt gtgtttttca ccgtcataat ttgtcatgtt ggttcctcct
    21061 agtagttcta tactttttca tcgtacaata agacagttta tgcgtcaaaa aacaaacccg
    21121 attcttacaa atatgtcata tttttccttc tgattcttga atgcttttga ttccttcttc
    21181 caaaattttc atttgtaaga ttgtttcttc atctttgatg actttttctg cgccattaac
    21241 taatgtctcg taaatccctt cgtagacacg gctgtaatca ccaacctcgg aaattacttt
    21301 ttcttcatga taactccctt gttcatctat ataggtcaat acaccataat gttcgggcaa
    21361 atcgatacca aagtcttcat gatcaggcat gtaaaacatt ttcagatgtt cttcttgtcg
    21421 atcttttgtt tgtttcacga acatcccttt ttttccgtaa acgacgaaac ttggacgttc
    21481 tttgatgcgg aaataactgg attttatcga aattttcata tttccataga aaaaatccag
    21541 atcgaagtaa tcattcattc gtcctttccc taaaagttga cgtacatcat agctgatatc
    21601 atctggttcg ccgaaataag aaagaacttg atctactgta tgacaagcat gtccatataa
    21661 atagctgttc gcagtagaaa attcatgcgt attttctggt acttccggtc tgaaataatc
    21721 ataatgcatt tctacttcta aaatatcccc taattttccg ctttcgatta ctttttggac
    21781 tgtcaagaag tcagaatcga accgtctgtt ttggtaacat tggataaata gacctttttc
    21841 ttttgctaat gcaaataact cttctgcttc ctttgacgtt tctgcaaaag gtttctctac
    21901 tagtacattc ttaccatgtt cgagtgccat ttttccatat tcataatgaa attgactagg
    21961 tgtagtgatg acaactaatt ggatctcagg atcatcccaa agatcagaca gctgatcagt
    22021 atattcgatg tcttcgaatg ttttccacac tggttcagat ggggaaaaaa tttttttgat
    22081 attgattttg ttcgtaagtt ttcttgaaaa aggcaaatga tagcgatttg tactctttcc
    22141 attgccaaga taagcgattg taagcatgag tggtgcctcc ttttattgat gttttcagta
    22201 tatcctagaa aagcgcagaa agtatttata atagctattc tggtaaaaaa gttcagaaaa
    22261 acacttgtta tcattcggtt tggtgaaatt aatgttcaaa gtaaggataa aaatcaaaaa
    22321 gatagtagcg gaaccaagtg tttatcagta agatagaatt tggaggtcag atcatgctta
    22381 ttgaagaaaa actaacaaaa caagagttgt ttaccacgac agagaaacgg attgtcgatt
    22441 acatccgtag gaatatcgaa gctgcagtct acatgacgat tgaagaatta gcaaaagcta
    22501 cgtatacttc ccattcagct atcattcgtt tatgcaaaaa aatgggattc agcggattta
    22561 aagaattccg tttcgagctg gggcgggaag ttcatcaatt gattgctcag ttcaatcaaa
    22621 cgattgatcc taattttcct ttttcaagtg aagatagcac tcagcaaatt gcaaagaaaa
    22681 tggcggattt atcgatccag tcaataaaaa aagcacaatt gcagattgaa catgaagatt
    22741 tagatcaaat cggtaaagta ttgaacaagg cacagcgaat ctttcttttt gcaaaaggtg
    22801 attctcaaat cacggcaagg aaattccaga ataaaatggt caagttgaat aagtttttga
    22861 tcatggctga agaatacagt gattcttctt ggaatgcagc caatttgact agcgaggatt
    22921 gcgccatttt tattagctac agcggtcgca tccatcatta tgaacgaata atgacctatt
    22981 tgaagcatgt agaggcccct accttgctga ttaccggaaa tcagcattca gaaatggcca
    23041 aacaggctga tatgtgtctt gttatatcgc aggaggaata tgattttgct aaagtagcga
    23101 ctttctcctc tcaaattgcc ttcgattacg tattaaatac gttattctca gtgatatatt
    23161 ctcaaaattt tgaagagaat atccgcaact tgaaaaacaa acaagaattg atgcaaaaag
    23221 gccttcttaa agaatatcgg aaaacttaag aaaagatcct catttagtaa taagaaagat
    23281 agtgtttgat aggctctctt tgatatcatc ataaaaacag gctgaagttt tctttttcaa
    23341 acctcagcct gtttgtttac ggaacgattc gaatagatat attatagaaa tgaggaatag
    23401 ctaacttctg tttcttattt tgaacgattg acgaaaaaga tatataagaa ggaggaaaat
    23461 cagtatacat gcagctaaca atccatacag gaaaaatcgt ttgttctcgg atactttctg
    23521 tacttctttt tgaacttctt ttgcatgata aggaacccgg tgccctctga caagtaagcg
    23581 atgactgttg accatataag gtgtacaagt taggagtgtc acgaaatcct gccctttttc
    23641 gattctcaga tcttttgtat cagtcggttc taccgtcttg atctgatcga cttgataagc
    23701 gagtgtccgt ccattgattt cgatatagaa agaatcacct aaagtcagtt tcggtaagtc
    23761 tgtgaacaac tttgcttgag gcagtcctcg atggctggaa ataacggcat gtgtattttc
    23821 tccccccgta ggataagacg ttccttccaa taatgaggca cctttttcta gcagcacagt
    23881 attcgtttca tcaaaaattg gcaaatggac attgatctca gggatcgtca aaataccgat
    23941 cgtatgtttc tcaaaatagg ttctatcctt tttcgcaggt tcttttttct tagtaaaggg
    24001 atctgcacct ggatttccac cttcttttgc taattgctgg tttttctttg tcatgttttc
    24061 ttggatttta gccatgactt cttcattttc tttgaccgct tgttgctgat aatgagagat
    24121 gatctgctga tccagataat tattcagcgc gtcgctaaca aatggataag ctagtatccc
    24181 tattcctgag agaagcaaga aaagcatcag cagatctaga agtttccttt tctttggttt
    24241 catttgtgtt ctccttgtga tgactgtttg ataataaaag aaaaaggagc atttgcgtaa
    24301 tccgctgctc ctttttccaa ttcttgcaaa aagactaaat ctgactgtgc ttgcgtctag
    24361 caaagtacag tccagcaatc agtagaagga ctactcctgc accgatatac acatagattc
    24421 ccttaccgcc tgttgaagga agtgtacctt tgtgtttatt tggtattttt tcaggagaaa
    24481 tcaactgtcc tgctgttaca taagattgtt catcgatagt aaatgctaca cggtttgtta
    24541 atggaacata tttttctggc gctttcgttt cttccagata gtacgtgcca tattttagac
    24601 ctgtcacatc gattaaaccg ttacttgtgg ttgtaaaaac cgttgctgat tctttcgccg
    24661 atacccagct gacggctttt gtggatgggt cgatcgataa atatttcgct gtgtcactat
    24721 cttgatcacg aacgacgaat tctgctccag caagtgtttg gtctgatgta acgtcaccat
    24781 ctactttaac aaatcgtttg cccccagtaa cgacatcgac tgacggtggt gtttgatcat
    24841 ttgtatgccc gttatcgaca tttgcttggt tagaaaatcc tttggttgga tctgcttttt
    24901 cgttcaaatg catatagtaa acgaatttca atgtaccgcc aggagttaat gaaggaatat
    24961 aattcggatc aactgaaacc gtgaatccgt ctgtttgctc agtgacagaa taatttactg
    25021 ggtcgatttc tttatttcca tcatataagg cataagcata cgttcctgaa gaatcattat
    25081 caaatgttaa agcagcgtca tgagtatcga taagtttgaa tgttgtgtac ttgttttgcg
    25141 ttccttcttt atcagcgata cctaatggga tattgacaga aatctcatat tgaatttttt
    25201 caccgattgc gacatctttt ccattcaatt gaggtgttgt tttatcaact ttagacgtat
    25261 catttttgat ggtcttttct actggtgttt ggctatttgc caggatctca aaaggcgtga
    25321 ttgtttgctt ttcaatcatt tccgcattat caggagcttt tacttcttct aaattatatt
    25381 ttccaacttc taaatgatta acgatcaact ggcctttttc aatagatgcc tcggcaaagt
    25441 cattgttgcc gatgtcataa gaatgaccag taatgaaatg tttggctttg gtttgatcag
    25501 ttgtccaagt gtacaatcca tctgtgacac tttggatgta ttttttgacg cttggtgttc
    25561 cttcttcttt agaaataata aattctgctc catttagtgc ttcgttttcg gcagtaccga
    25621 tttttgtaac tttcaacgtt ccatcattac cgactgtatt tttagggtag agatggatag
    25681 tatctagttc ttctgtcccg tatttataag agccatctgc ttgtttgatc atctcatata
    25741 cagggaaagc taaaaccatg tttgcggcag ctgacactcc gtcttttggt tcttctttga
    25801 tcgtgtagac tgcatctttc ccattttgtt ttttaggtaa agataaagtg acatttccat
    25861 cagcatctgt cgttcctgaa gcaactggtg taccaggagt caaagactgg actgcttgtt
    25921 ttgctgcatc cacggacgct cctttatctc gttgcgcata aaattcttga gtgacgttat
    25981 aaactgaaaa tgaaatatcg gctaatcctt ggtattgatc gaattcgctc atttctttcc
    26041 cgctgttttg gattaaagga tcgggtaaat cagtcatttt ctttttatga aggatgactt
    26101 gagctgctgt ctcctctgca aacacttttt ttgcgccgaa gctgtttgtg agtaatggta
    26161 aaataaggaa aaggactcct aacataacgt ttattttttt atgatttttc attttttcac
    26221 tcctgttctt tttttgataa acaaccagat tgcaaagctt gcgaatacca taccaacaac
    26281 gcctaaaagt gtatttttcg tttcgtttgt ttttggaaga aatggacggc tattttcttt
    26341 tttattgact actttcaata tactgtccgc ctctttatcc tcagaaagaa aagttgaaat
    26401 ggtaaacgga atttctgttt cacttaaaat ataaccagaa ggtgcttcga tctcttttaa
    26461 tcgataactt cctgttttca acccggaaat tgaaaaagcg ccatttttat cggaaatcag
    26521 gtgaagcgca tctgattcgt tctttgtcca cttgtatccg ttggctgttt gctggaggta
    26581 atttcctgct ttgtttttaa taaggaatac tgcgccagct aatcgtttat ctggtttatt
    26641 tgtctcgatt ttgacaaatt gcttactccc tgtatataca gagactttct ttgtactgac
    26701 accaaaacca aaatccagtg ttccgttgtt gttgatttcc ttgttcgcct gtgctgtact
    26761 gcttagctgc atctgataag aaatggtcag tttttttcca gcatattttt ccaacgaagg
    26821 gatcgaaaat aaaacatcaa atccgtgagg tttcttgtgt atgacaaagc cttctgtcag
    26881 cttttctcca ttcgatgaaa tcgttaaact attaggtaaa aacgttaatg cttcatccgc
    26941 actatctgac aattcgaact tttgatagtc aaggatattt acaggaattg tcgtatgcaa
    27001 ggaataagtg attttttcac caatcgtaaa atcatttcta ggctcttcta ataccttctc
    27061 aaaaggtgga tcagggtagt cgttttcttc atttttagga tacaaatgga tagttgaaag
    27121 tttttgattg ttttgtccat gtacaggaag aacaactacc atattctctg ccttttcttt
    27181 gacgacttct ggtactttgg attcaatgaa aagatacgct ttatctcttt tttcttgatc
    27241 tttagcggcc agagaaaaag aagcgatacc atcttcgttg ttaagagttg tagttgttgc
    27301 ttctgcggta aacataccgg aagacgcacc gttttttgcg atctctgctt gtgcttcttc
    27361 taccgttttg cccttttccc gtagatggta aaaagaatct gtgacatcat aaacttggaa
    27421 tgtgacacca tttaatcctc gatacgtttg taataaagct ttttcttgtc cgtcatttgg
    27481 atgatttttc ggcagttgcc cgtttgggaa aagcaatttg tgtaaagtaa tctgaaccat
    27541 ttctgtttct gtttctgttg ctacctgagt aaaagctggt ttaaatagta acaagaagag
    27601 acacatacta agccaaccaa gttttttcat atttagctgc cccctctttc ttttttcaaa
    27661 aaaagatacc aaatagaaaa cgcacaacca atcatcccta ctagatagat tcctaaacgg
    27721 ccaattcctc ccgtttcagg taatggtact tttgcctgat tcgtgatgtc taaagaaatc
    27781 tggttgtttt tggctcctgg tgacagaaca gattcatgat cttgtccatc cacttgaatt
    27841 gacccatctt cgtgtataac tatagtaact ggctctttta gaccttggta tccttctggt
    27901 gtaaaagttt cggtcagcgt ataagttcca ggttttaaat tttcgaatag aaaggtatct
    27961 gtttcttgtc catcttttgg cgattctaag tccatttctg gtccctgcag tctgaatttt
    28021 gctcctttta atgtctgtcc gttgtcttct tttttgtgta ccgttagatc aaacgctttt
    28081 agtcgatttt gatgagtgag cgtccataca ttatttgtca tctcggtatt ttttcccgtg
    28141 taaatgattt ttccatattt atcgatttgg aattcataat ttcccggcga agtatcatat
    28201 ccggcaggac cagctgtttc aacgactcga tatttaccag gtgtgagtga atcaaaactg
    28261 gcaagacctt tttcattcgt tgtttggctg tcaattggct gataagtacc atttgcttct
    28321 tttttctgta gggaaaatgc tgctccttta agatttatct ctttgtccgt cccttgcatc
    28381 gcatacttac gtactgctac aggaacttca acaaaaggat tttcaatagt caactggatc
    28441 gtatcatcgg aagtagtgac tgtttttcca tcaatggtta ccgtaccatc agaagcgatc
    28501 ttgatttccc aagtagtctt tttgcttaat ccatgccctt ctggagcttt tgtttctgtc
    28561 agcgtatagg tcatttcttt ttgcaatttg acattttctg gaagagaata ggttccgtcg
    28621 ccatgatctg ttagtaaagt atcaatagaa tctcctgtta atttgaaaac agcgccaata
    28681 agatcctttt cacctgtaga ggaatttttc gttattttca agtttaacgg tgtgaattgt
    28741 ttagtatttt tccatgtcat tgcatctatt tgttgagaat cgtatcctgg tacaggtaat
    28801 tctttgattg tttggtaact gaatgcttga ccttgattat tgtattgagg tagtgataat
    28861 atctcttgat aactttctcc gctatttgca gataatttgt caatgtctgc acgttcccac
    28921 gtatttgttg tatctttagc tggtttaatg attcgaatat atccgttttt ccaagctgca
    28981 gcatttgtcg tatgttcccg ttgaatctca aaagtaactt gatctggacg atcagctaga
    29041 ttgttgtcaa attcttccca taactttttg atgtgaagac tgactccggg agctttagca
    29101 gatggtatac cgaattcagc taattcattg gtatcaatgt ttggctggaa agttgtcctg
    29161 ccgttcattt gataccagaa atttggatgg aagtcctcat tttctgtttg gattctcact
    29221 tggtaatgga tttggatttc ttggtctttt cctaaataga tctgattgct cttgatggta
    29281 tttccttcta tggaaataga tggagtgacc gttgtaggac ttgtccccac actcttgact
    29341 gaaagtgtac caggctgata aatgaatggt tctgcgattg gatcatttat ttgtccattg
    29401 cttacagttg ctgagatctg tacagctttt ttggctaggt attcagagat atctgttgca
    29461 tgatcagctg attcatagta aagatcgcct ttttcatctg atgaaaccat ttgtcgcata
    29521 cgagactcta cttctgcttt tgagagacca gctgccggat cgctttgaag ttggatgcca
    29581 agaccatgta tttcgattcc tcgttctttg agtgccatcg cttctccgat ggttgcgata
    29641 aacgtactgt cgattcttct ggatagattg ttttggtcag gtgcatcata gattcttgag
    29701 attagagaag tatttcccgg ccgatcttgc gtattagaaa actgagttcc gtaataattg
    29761 ctgcttgatt gtgcgtgtac ccgctgtact ttataggaaa atgttggtac accatccgtc
    29821 agcaaaacga tcactttttt atgtccattt ggaacggata gcatgcttcc tgcatctctt
    29881 agtgcttttt gtgtaaaagt accaccattt gtccgtgaag gtgtaatgga ttttacttga
    29941 tttttcactg aatcaaatga acccatctgt actgcaccgt tactgtagct atatccttcg
    30001 cttgagtagc cgacatatcc catattgatt ttgtctgtga taccgctatc tgctaaagta
    30061 tcgacaaaac gatcgacacc aatctttact tcaccgatcc gattattgtc gttcatactt
    30121 cctgaccagt ctacgaccaa tacgagatca agaggcgtga tatctttttg tacatttcca
    30181 cgagcattca aataaacatc aaacaatccg ggtgtacttg tttcctttgc atactttcgt
    30241 atcgcatagt ctgcttgatt accggttcct ccatattcga tatacgaatg ggtccgatca
    30301 ttaggatctc cattccaaga atttatacca tcccattgat ttgttccgtt tttattgcct
    30361 tgatgatcaa gaacatttgt atttcctgta ggttgccaac tggctttagg ataagtgccc
    30421 tgatcatctg ttgtatattc tgtaggaatc gtttgattag atggcacact cacagctggc
    30481 aaggataatg taggcaatgt aaatgggctg acagaatttt cgttttcttt tgatgattct
    30541 tcttctattt cgtctggctt tggtactgac acatctgtat ctttcttatt ttctgtctca
    30601 tcaataatgt catattcttt attatcgacg atcagcttgt ttgcctggct gtggtaaagt
    30661 gctggatcga ttggaaaact cagatcgata gtttgtttag tgtttgatga gatttccaac
    30721 gtaattttcc cgctatttac ctgataagca tagccatctc cttcttttct ttccacatca
    30781 cttaagtaat tttcgactag accaatttct ttttctatct tttcagcact ggtgttattc
    30841 gcatttagct tgatgttcag tgcttttttt ccagactgat ccgaaatgac ttcagctgaa
    30901 attgtttcta aaactgttgg atcatctgta gtgtctgcta ttgcagataa tggcacaaag
    30961 tttgataaac tcaatattat cagcatgaaa ataactttca gtttcttccc tgtggtcgtc
    31021 atttttcccc tcctttttct ttttttctgt tttgacgtga atagtgaaaa ttattaaaat
    31081 aaacaggcgt tacataattt tatttatttt aatatgataa ttattatacg aagggcgcta
    31141 aagggaatca caccaatttt cataccaatt ggtttcattt atgaagttga ttccttcgat
    31201 taatgagcgt ttcattgaaa gaaaagggtt gagggagaaa aacatatgat caggttgttg
    31261 gaacgaaact atagaaagat ggaaaaaatc attcgaattc tgtccatttc tgacaagtgg
    31321 atgactaaaa aagaacttgc caaacgaatt ggtagttcag aatctacatt tgtaaggtat
    31381 atcgaagaga tcaaaatccg ctggggaacg gatgtaacga ttcaatcttc acaaaaattg
    31441 gggtatcgtc ttgaacattt gaatgtacca gcttatttaa atgttctgat ggaaatgtcg
    31501 caaagttcta caaacagtcg tttattaaat gagattattg tcaatccggg taaaacgatt
    31561 gagtattatt gtgaaaaaat ttccatcagc cggtcttctt ttacacgtaa gttgaaacaa
    31621 tgcaatcaaa ttttagaaag ctatttatta aaagtgatcg ttgaccaagg ttttcagtta
    31681 actagcctta aaagtgagct ccagttgcgt atctttgtta cctttttctt tttaagtgac
    31741 tacggaagac gcacgttgcc atttccaatc gaaaaaaaga agatcaaaga aattatggtc
    31801 aagaataatt gtcagatgaa tttgtttcag gaagaaagcc catatgagca atctttcttt
    31861 attatgtatt ttgttgtgca tctcatgaga gaatcccaag gaactccatt tgaatggaaa
    31921 gctggagact cttatgtaca gttgataaat atcgataaaa aagacttctt aatcttgaaa
    31981 aatctcttag gaaaattgaa gtacagcagc tatataaaag tagtgaacta ttttgtcaat
    32041 acgatttttt cagaattttc ggagaaagaa aaaaatgaaa tcagtgagca gatacgaaaa
    32101 aatatgtcct actgttcgtt ttcatccgct gattgcaaag aaaaaaacga agaatatgtt
    32161 gttcaattat taacgcaaat ttattttttc tcccgtattt tcccatacga tacgactcat
    32221 ttgacgatcc gtgcaactta ctttgcacag cagatgcaac accgccagat acgtctatat
    32281 gctggatttc gtgcagaact tcaattttat tccactctac tgaatcagaa tctgatttat
    32341 tatttatcta gctatatctt ttggatgctt atcggtaatc ctgaaattca ccattatact
    32401 tctgataaaa aaatactgat tatcagcgac ttaagtcttc gacatagtca atatattgaa
    32461 gaatatatca gtgatattct tgctgtgcat aaaattcact ctgagacaac tgctattact
    32521 gaagatcagc tgtcgaaata caatcttctc gagtatgatc tgatcgttac gaatcaaccc
    32581 attttgaatg cccatgttcc tcatatattg attgatgata gtgtgtcatt cgcaaatgaa
    32641 gaagaactca tccgcttatt cgagttatga ataatcaaaa aacagctatg tataaaccac
    32701 cctgataaaa atttcaggac aaatacacat agctgtttct ttttattgta ttccttcagc
    32761 aatccaacga gatttatagc gaaagtcttt taacaactct tcttttgtcc aattatttgc
    32821 aatgagatcc gtcaaagtgt tcattacgag ggtcatggaa aagtatagga aactaactgc
    32881 ttcttccgac gattgaatgg agaaatgatt gattcttaat aattccagcc atttttcgtt
    32941 cattggagaa tcagccgata gttctctacg tttggttgtc tgctgatcat ttcgctgggt
    33001 taacaagtat aacctttgcc aatagatact ttcgtgatct aagtcgcagc accactctaa
    33061 atatttttcg atccccaaaa agaaatgttg tttgttttcg ctaatgaatt ttaagatatc
    33121 ttgatggact atgtgagaac tgcttttgat cgtatacaaa taagcatctt ccaaatcttg
    33181 aaaatattta taaaaagcac cgcgcgacat ccccatcttg tcaacgattt ctgagacttt
    33241 gacttggctg atgtgctgtg agcaaaatat ctccagtaat aggtcatcga ttctctgttt
    33301 ctttgcgttc gataaattga aaaaagtttc ttttggcatc cacatctctc ctttatctct
    33361 gattatacgt ggatagccct tcattgtcat gaaggattca ttccttcttt ttctcttctt
    33421 ctgtcaagta cccatcttcc attcgataaa cgcgatcact ccattgaatc atacggacat
    33481 catgagtaac cataatagtc gctttttgtt tctcatgagc ttctttaact agtaatttga
    33541 cgacttcata tgcatgatct gtatccaaac tagctgttgg ttcgtctgct aagatcaagc
    33601 ttggctcatt atataaagcg cgagcaattg ccactctctg tctttctcca ccagaaaggt
    33661 ctttaggata actattttta agtgactgga tatctaaaga ttgcagcaag gaatcgattt
    33721 ttgttgaatc ttcttttttt gaagtaactt ggtcaactag ttcaaattgt tcctttaccg
    33781 ttaaaaaagg aatcaaatta gagctttgga gaataaatcc tatttcttta aagcgtaaat
    33841 ctgctcgttt tttttctgga agctcagtta gtgagtgacc gttgatcact atttctccgg
    33901 aagtcggtgt ttgcaatcct cctgaaatgg taaggaaagt acttttacct gaaccagaag
    33961 gaccaatgat gctgacgaat tctccttcct ttacataaaa atcaattgct ttcaaagctg
    34021 agacctttgt atgaccagaa ccaaatgttt tggtaacttt tttcatcgtt aatatttttt
    34081 tcatttttat taacctccta ttgctgtaat tgggtctact ttggttatcg tacgtatcga
    34141 aaacaatccg cctagcattg cgacaatgat caaaatccca ctatatagca accattgtga
    34201 ccaaaaaaca gcaaaaggca tcgcgcttgg taaaatcaga ctagtcaaat aagcaaacaa
    34261 aagagcaagc agaacgccta ccaccccaac aataaaggac tgtgctacta aagatttagc
    34321 gatgaagaaa tttttgatcc cttgtgcttt cattactcca aaaatagcag tcttctgaag
    34381 tgtcatcacg tacatgaaaa taccgaccac ggcagcaacc actaagaaca aaaagtatat
    34441 catcgcattt aaggtcatat tttgggcaga atagccagga atactttcaa tgaatgtccc
    34501 aatagttaat aactgtagac ccttcgatgc tttttctttc gaaattttag ctgaatcctt
    34561 tattacgatc ccattgatcg gctgttcttc ttcagaagca aacggctgtt gtccatactt
    34621 caaagcagtc cacgtatcta gggacgcata gatgacggga gaaactgtgt aataagtttc
    34681 aggaaagata ccgacaatcg tcaaaggatc gtcgtaactg ccaattttga tcgtatctcc
    34741 aattttatag cctgaatcag ccagattttg agagatgatg atttcattct ttgttttaaa
    34801 ttcatgccct ttcgtgagtt ttggtaataa aaatgcttct ttcgttgtgc cgaaaactgt
    34861 aacattttct ttgttttttc ctttgattgc tccgctgtac aatccgattg gtgctttctc
    34921 tcctccttca atgtatttca gatctcctct tgttaattgt gaagctgcaa atacttgatt
    34981 tgcatcctcc gacaaaacaa tctcttgtgc gtcccaatca tcgattgctt ttttaaactc
    35041 ttctgaaagt ccattcgcta gtcctgacaa catgaatacg acatacgcaa tcaagaacat
    35101 aataccgacg atcaagccat atcgtaattt agaatagcga atttctttga tagctagaaa
    35161 catttgtttt tcctccctat gatagattga tagtgacaaa atgtcacttg ttgaatagtg
    35221 taactctaaa gtgacaattt gtcacttgtg ttgttttttt cttatcaata aattgtctaa
    35281 gacatctttc gataaaacct taacatgagt cataaaaaat ttatttaagc cttatttatg
    35341 ctttccatga taaactaaag tgaccaaatc aatgaggtgg gaaaatgatt aaactattag
    35401 tagtagaaga cgataaagta ttatccaata atataaaaga aatactcgct gcaatcggcg
    35461 agataacaca agtttatgat ggtagtgaag gactgttcga gttggaaagt ggagtttatg
    35521 atcttgcaat cttggatttg atgatgccgg aaatgaatgg atatgaagtg ttagcaaaaa
    35581 tacggaaaga aaaaatacag actccagtat tgattttgac tgcaaaagat agtttggaag
    35641 ataagattga aggatttgaa cgaggtgcag atgattatct aacaaaacct ttctatcgag
    35701 aagaactgat catgcgcgtg aaagcattat tgaaacgctc gctaggtctc tttgatgaaa
    35761 atgttctgaa gtataaggat atcagttgtg atttaaaaag caatgaagtc ttgtataaag
    35821 aacaagtttt gcccatacaa ggaaaagagt ttgaattgct cgtttatttt ttacaaaata
    35881 agggaatcat tttgacaaaa gagcagatat ttgaccggat ctggggattt gattctgata
    35941 cgacgattac agttattgaa gtttatatga gcaacttacg aaaacatctg cgaagtactg
    36001 gattggataa agaaatcaaa accttacgta atgtcggtta tatactgcaa agggtgtgat
    36061 gcaatgaatg gagatattac acgaaagcaa cgtagtcgct tttttgcgac aaatgtagca
    36121 gcatttgctt ttatcttttt tcttttggga ttcattactt tacagatatt aaaccaatct
    36181 gcatacagag aaacagatct gtcattagag aaaataaatt ttgattctcg aacagtacaa
    36241 ttagagatac aaagatatca gcaaggcgat ccctttttaa acccgactca aacggaacaa
    36301 aacagaacaa acatggaaca gccattaatg gaaccatcaa atgaccgttt taacactcaa
    36361 gtgatcttgt ggtctaaaaa tggtgagata ttgaataaag cagctattgg tgggcgtttc
    36421 aaccaaatca aagaattaaa aatggatacg aaaaatctga ataccatcca aaatattgaa
    36481 ttaaatgaag acagtggctc atctgccctc tctttccgtt cgattacgaa aaaagcggag
    36541 acgaatcaag atggcgttgc ctacatccaa attttagaaa atacaaatca aatcaagaat
    36601 tcattagcga cttttcgcac gattatgatt ttgtgtatga ttgttttttg gattctctct
    36661 attggtatca gttattactt gtctagtcta agcatgcgcc ctattattct ttcttggaga
    36721 agacaaaaag aatttgttga gaatgcttct catgaattgc gcacaccgtt aacgattatt
    36781 caaaatagtt tggaacatct ttttaccaag cctaatcata ctattattga agaatccgaa
    36841 agcatcgctc aagcattgtc agagacgagg cgcctcactg gattgacttc ggatttgctg
    36901 acaatcgctc ggaatgattc tgatcagcag ctgctttcaa agcaaatgat caatacacaa
    36961 gaatatatcg aacaacttgt taaaccattt caagagatgg ccatcataga tggaaaagag
    37021 tttattctcc ataacgatgc aacattagaa gtaccaattg atgaaaaaaa aatccatcaa
    37081 gttttggtta ttttgctgga taatgcatta aaatatacga atccagaaga taagatcatt
    37141 ttggattcat ctgttaacca taaagaatgg ctgattcacg taaagaatac tggcccttct
    37201 atcagtgaag aagatcaagc aaggattttt gatcgatttt atcgggaaga tcaatctcgg
    37261 gcgaaagaga ctggcggata cgggcttggc ttggcaattg caaaacaggt aatcgaacag
    37321 catcatggac agatttctgt atccaattat cttccacaag gagtcgattt taaagtccaa
    37381 ttgccgttga agcctaaaaa ataatgctta tccctaaaaa agggctgtga caaaaatctt
    37441 gtcacagccc ttttttgttg cgaataaacg gtgttccaga agtagcttct tcggaaataa
    37501 gccgaaattt ctttaagctg accacttctg tcacaacctc tttagcttac gcttacgatt
    37561 ttttattgcg gtcttcaatg tgtacatcac cgcttgtgtc aatatccaat tcttctcggc
    37621 taacatcttc tgtcactttt tcaacatctt catgttcttc tttatgaatc ccaacttctt
    37681 cacgaataac tgtatgtttg cttacatcta cttgctcttc tttgattggg atagtaatcg
    37741 tgtcatcttc caatttttcg tctgttccct gtgaagattg atctgttact ggtttgcgtt
    37801 cgatgacgat ttcttcacgt ttgaccggta cttctaccgt ttcagtatcg ttgaccacat
    37861 gtttgtggat gtcgacttct ccagttgtca catcatgtgt atttacatct aatttttctt
    37921 cttttagttg aattgtatca tcatctagat ttggtttgcg atcgatgtct tcagtcttgc
    37981 ttgtacccat tgtatcagtc tcgccaggta cgtccatcgg atcagttcct ggtgtcatat
    38041 tcaatggatc cgttgtattt tgaaagcctg tcgtgccacc tacgtccatt ggatctgttc
    38101 cagtgccagt ttctaatcca gtccccattg tgcttgctgg gctaacagta tcttgtgtat
    38161 ccattgtatc ttctgttgtt tctggctgac gatagccttt tactgtgatg acaaattttc
    38221 catcagaaat atctcctcta tattgatata aaggatcatt ttctggtgta gccgtctcag
    38281 aatcataggt atcaaaagaa aaagtatctt ttattttttc ccataaagaa cggtcttctt
    38341 caccatccat ccgattttca tctgtttcaa catctatacc agacaatccg tcaaatccta
    38401 gtctagatgc tgcttcatca gtagtataaa taacgatatc atctcgttca tacccttcgt
    38461 tacgcaaccg ttcaattact gataatgctt cttccctcgt actatagctt ccgatgaccg
    38521 ttaaattttt ctcttccatg taaattcctc ctagcaaata gatttatgat tggtatattg
    38581 ttacttataa atttattcta taggagacga ttgttttcta caaatattta gattggaatt
    38641 tgattaaaac aatttaattg aaatttgaaa acatttatgt taatgaaagt catattctaa
    38701 taaaatgtca tttgtttcta tatgaatttt tatgaaaaat ttcatataat ttccactcgt
    38761 tgtgatggtt taatttatcc aatccatcaa taagcaaaca acttatataa aaaaggatta
    38821 attctcaata taattgctcc taccatagaa taaatcttca tgtaaagtaa tgaagtacca
    38881 actatttcta atacttcttt aagaattatc ccaacaatat cgttagacaa accattattg
    38941 aataaatgga gagccaatcg attctgaaaa aatgttttct aatttttcgg aaataaaaga
    39001 aagagcctcc tgccattaga acgaaccaaa tccatttcat tgctcatgaa gtaaccacat
    39061 agctaaaaag aggataaatc aattaaaaga tcaaaagaat gactgcacta ataaaataac
    39121 taaaaatgta tcttcttact tcatatcttt tagctagtac ttagttaaaa atttgcttcc
    39181 taagatcaag acaaactgtc tatcttcatt tgatgaaatg cggtaaaata tagaaaatga
    39241 acactattgg agggaatttg taatggacag caaaactaga aaacaactgc aagaaaagtt
    39301 aaagcaacgt acacacttgc tcccttccgt ctttcaacag tttttagaag aaaatcgttc
    39361 ttccctttca ttaggcagtc gctatgaata cgcaaaagat tttcatctgt ttactgatta
    39421 tttgagaaaa gtattttctg aagaagtgga tgatcagctg attatccatt tagaaaaaca
    39481 agattatcag aatttcttag ctaaaatcta tcgacatact cgttcgttcc aaactacagc
    39541 gaaccaagaa acggagcaat tgtttgaaaa tagctattac gggatttcaa ggaagcaata
    39601 ttcattaaat cattttttac gatttttgta tcaaaaagga ctgattgaag aagagatttc
    39661 tcttttgggt acaagtttac cggaaacaac caaagcagct ccgcgatata tcgatgcaga
    39721 acttttcaaa gattttgagc atttgtttat cccgattgaa ggctttcaaa caagcagaga
    39781 agctagcttt gaagaaaaga atagaccgag gaaccttgca attactgcca ttcttctgta
    39841 ttgcggatta aagatccatg aagtagtaga acttaaacgt aaagatgtat ctttgaccaa
    39901 gcagattctt aatctgaata gaaaagaaaa cagactgaat aaagtaccaa taccaaaaga
    39961 agcgatgcca tttctggaga actattttaa gttaacagca caaaatacgg acgaaaattc
    40021 ttttgttttt cgttcctcac atgatcagca aatttctcct cggactattc gccaaatttt
    40081 gagcaaaatt acagtatata aaaacgtatc gccagaacta tgcagaaaaa catatcgtta
    40141 ttatgcagaa ctatatttag atgatgctga cgcggtaaat tatttatgtg gtaatcgata
    40201 cctctcatcc cattcttttc aagatatctg ggaaaagatg gttgattttt cttatcacga
    40261 attagcggca ttcgttcggg tttcttccat ataaaacaaa tgtatgatct ttttttcaca
    40321 ataaactatg ttattatata aaggattatg ttacgattat cttgaatttg tatattactt
    40381 aacaaaagat aatggagtgt gaatgatgga gaccataacg tattcccctt tgaacttatt
    40441 tacgaatttt caagaagctg cagctaactt ttccgagacc ccgattatct ttgatgagcc
    40501 actttcagct ttcccagaat taggacttga aacaacttac aaaaaatgct gcgaaagtgt
    40561 gttgaaacgg gcttatcaat tggctcatct tggagtgaaa tccggagaca aagttattat
    40621 ttataagagt tccgcttttg acacatacct tctagctgtt tctgtgtctt accttggtgc
    40681 agtgcctgtc atgacttctt atcatctacc aacaacaaca atggaagtat ttatcgatcg
    40741 tttagaagac cctttcattt tatttgatga tgagacaaaa aagcgagtga gagaaatttc
    40801 aaatggaaca aaatcaaaac agattcc
//
LOCUS       DAFEKH010000023        39890 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.024, whole genome shotgun sequence.
ACCESSION   DAFEKH010000023
VERSION     DAFEKH010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39890
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.024"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(28..726)
                     /locus_tag="LP386_001344"
     CDS             complement(28..726)
                     /locus_tag="LP386_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HBL1918587.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(719..2071)
                     /locus_tag="LP386_001345"
     CDS             complement(719..2071)
                     /locus_tag="LP386_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HBL1918588.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(2294..3694)
                     /locus_tag="LP386_001346"
     CDS             complement(2294..3694)
                     /locus_tag="LP386_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HBL1918589.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            3855..4592
                     /locus_tag="LP386_001347"
     CDS             3855..4592
                     /locus_tag="LP386_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HBL1918590.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            4717..5196
                     /locus_tag="LP386_001348"
     CDS             4717..5196
                     /locus_tag="LP386_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HBL1918591.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            5193..5960
                     /locus_tag="LP386_001349"
     CDS             5193..5960
                     /locus_tag="LP386_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918592.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            6190..6759
                     /gene="lepB"
                     /locus_tag="LP386_001350"
     CDS             6190..6759
                     /gene="lepB"
                     /locus_tag="LP386_001350"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBL1918593.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(6863..7465)
                     /locus_tag="LP386_001351"
     CDS             complement(6863..7465)
                     /locus_tag="LP386_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBL1918594.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            7571..8040
                     /locus_tag="LP386_001352"
                     /pseudo
     CDS             7571..8040
                     /locus_tag="LP386_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            8146..8730
                     /locus_tag="LP386_001353"
     CDS             8146..8730
                     /locus_tag="LP386_001353"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HBL1918595.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            8733..9806
                     /gene="prfA"
                     /locus_tag="LP386_001354"
     CDS             8733..9806
                     /gene="prfA"
                     /locus_tag="LP386_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HBL1918596.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            9799..10638
                     /gene="prmC"
                     /locus_tag="LP386_001355"
     CDS             9799..10638
                     /gene="prmC"
                     /locus_tag="LP386_001355"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBL1918597.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            10631..10810
                     /locus_tag="LP386_001356"
     CDS             10631..10810
                     /locus_tag="LP386_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918598.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            10832..11857
                     /locus_tag="LP386_001357"
     CDS             10832..11857
                     /locus_tag="LP386_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HBL1918599.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            12032..13276
                     /locus_tag="LP386_001358"
     CDS             12032..13276
                     /locus_tag="LP386_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBL1918600.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            13429..14376
                     /locus_tag="LP386_001359"
     CDS             13429..14376
                     /locus_tag="LP386_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL1918601.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            14510..15139
                     /gene="upp"
                     /locus_tag="LP386_001360"
     CDS             14510..15139
                     /gene="upp"
                     /locus_tag="LP386_001360"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HBL1918602.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(15278..15520)
                     /locus_tag="LP386_001361"
     CDS             complement(15278..15520)
                     /locus_tag="LP386_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918603.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            15641..15713
                     /locus_tag="LP386_001362"
     tRNA            15641..15713
                     /locus_tag="LP386_001362"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:15674..15676,aa:Thr,seq:cgt)
     gene            complement(15832..16470)
                     /locus_tag="LP386_001363"
     CDS             complement(15832..16470)
                     /locus_tag="LP386_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBL1918604.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(16593..17225)
                     /locus_tag="LP386_001364"
     CDS             complement(16593..17225)
                     /locus_tag="LP386_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBL1918605.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            17576..17875
                     /locus_tag="LP386_001365"
     CDS             17576..17875
                     /locus_tag="LP386_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBL1918606.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            18370..20535
                     /gene="acm"
                     /locus_tag="LP386_001366"
     CDS             18370..20535
                     /gene="acm"
                     /locus_tag="LP386_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HBL1918607.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(20807..21292)
                     /locus_tag="LP386_001367"
     CDS             complement(20807..21292)
                     /locus_tag="LP386_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBL1918608.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    21382..21727
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            21772..22413
                     /locus_tag="LP386_001368"
     CDS             21772..22413
                     /locus_tag="LP386_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBL1918609.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIIMKQVEGKLNYYR"
     gene            22432..23067
                     /locus_tag="LP386_001369"
     CDS             22432..23067
                     /locus_tag="LP386_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBL1918610.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            23085..23900
                     /locus_tag="LP386_001370"
     CDS             23085..23900
                     /locus_tag="LP386_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL1918611.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            24219..25655
                     /locus_tag="LP386_001371"
     CDS             24219..25655
                     /locus_tag="LP386_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL1918612.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            25844..28291
                     /locus_tag="LP386_001372"
     CDS             25844..28291
                     /locus_tag="LP386_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBL1918613.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            28521..29588
                     /gene="rlmN"
                     /locus_tag="LP386_001373"
     CDS             28521..29588
                     /gene="rlmN"
                     /locus_tag="LP386_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBL1918614.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(29781..30884)
                     /locus_tag="LP386_001374"
     CDS             complement(29781..30884)
                     /locus_tag="LP386_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBL1918615.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            31437..31985
                     /gene="aac(6')"
                     /locus_tag="LP386_001375"
     CDS             31437..31985
                     /gene="aac(6')"
                     /locus_tag="LP386_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBL1918616.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            32531..34192
                     /locus_tag="LP386_001376"
     CDS             32531..34192
                     /locus_tag="LP386_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL1918617.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(34262..34609)
                     /locus_tag="LP386_001377"
     CDS             complement(34262..34609)
                     /locus_tag="LP386_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HBL1918618.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            34693..35634
                     /locus_tag="LP386_001378"
     CDS             34693..35634
                     /locus_tag="LP386_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1918619.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            35635..36678
                     /locus_tag="LP386_001379"
     CDS             35635..36678
                     /locus_tag="LP386_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1918620.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            36684..37754
                     /locus_tag="LP386_001380"
     CDS             36684..37754
                     /locus_tag="LP386_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1918621.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            37744..38697
                     /locus_tag="LP386_001381"
     CDS             37744..38697
                     /locus_tag="LP386_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1918622.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            38709..39719
                     /locus_tag="LP386_001382"
     CDS             38709..39719
                     /locus_tag="LP386_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1918623.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
BASE COUNT        13605 a         6869 c         8129 g        11287 t
ORIGIN      
        1 tttgtcacat tccccttttt cgaataacta ggctgtttgt ccttcaagat agggcagatc
       61 caattcttta ccgtaacgtt gttctaaagc taggcggatc aaacgagctg ccaggttctc
      121 atttcttgca aggataggtc catggaaata agaaccgaag acatttcggt aaatgacacc
      181 ttcagattgg tcttcaccat tatttccttg accttgtacc actttcccca aaggtcgttc
      241 accttcacct aagaaagtcc gaccattgtg gttttcaaat ccataataag tttcattgaa
      301 ttcttcgtta tggataacga tatcaccgat aaaccggtta ttttcctgac ttaacgtgta
      361 gtgatccagt gcactgattc cttggatctt ttctccatta gctcccatgt agtagtgacc
      421 tagcaattgg tagccaccac aaatggctaa catgacgcca tcattttcga tatagttgat
      481 caaagaatct ttctttttct ggatgtcttt tgaaatgatt aattgctcaa agtcttgacc
      541 accgccaaag aaaaccaagt catatttatc agcatcaaaa ggttcatgta tactaacgat
      601 ctccgtatgg caagaaaccc ccattttttc tgctatatat ttcaacatca aaaggtttcc
      661 gttatcacca tatgtgttca tcaaatttcc ataaaggtgg gcgatattga gttcataatt
      721 agccacggtt cattcctcct ttgataaatc cttgagcagc tagttcttta cgaagctgca
      781 atacagcagt gtaagtagct aaaatataga catgctcagt tggcaattct ttgatttttt
      841 cgattacttc tggtaattct tttgtttctg tcaatttatt ttctggaatc ccggcaactt
      901 ttagacgtaa agtcatatct gtatgacggt ctcctccaga aataacagct gggatatcca
      961 tatcggcaaa gttttcaaaa ttaccatccc aaatccagct gacatcgatt ccgtctgcgt
     1021 aattggcatt taataaagcc actaaagaaa atggataagg agctagacca atcatatcga
     1081 ttacttgatt gatacctaca ggatttttga caagtactaa tgtacatttt ttcccattga
     1141 tattgatgac ttcttgtcgg ccgaatactt tctcgtcata tcctaaacct tgtttgattt
     1201 tatcaggatc gacattgaag tactctgcca ctgcagtagc tgctaaagca ttgtagacat
     1261 tatacatacc gccaacttcg attccgtatt catgaccatc gatcacgaaa tctgctgaca
     1321 cattgtccat ccgtaccata tcagttaatc gataatccaa ttcaggacgt ttgaagtcac
     1381 aatttggaca gtaatatttc cctaagtttg cataagtgat cattttataa tgcaagatgt
     1441 gatgacaatt tggacataag acaccgtctg tattgtaatg agccatttgt tcacgatctt
     1501 cttcatggtc aaagccataa tattttctag gattgactgt ttcgatagaa ttgaagattg
     1561 gtgaatcacc gttactgata atcgttgcat ttggtgactt tgcggcaccg tctacaatca
     1621 ttttataggt cgtatagatt tctccatacc gatccatttg atcacggaaa atatttgtaa
     1681 ataagaacag ttctggtttc atatattctg tgactttgct caaacttgct tcatctattt
     1741 ctaggacagc aaactttttc tgtccttttt ttggttttgc ctgcaagaaa gtcgatacaa
     1801 ttccctgtac catattcgca ccagtagggt tggttagaac ttcatcgaat tgctggcgca
     1861 aaatattgac tgttaaagcg gtagtcaatg ttttaccgtt tgttccggtg acaacgacga
     1921 cttggtagtc ttttgccaaa ctatctagta tatgtggatc gactttcagc gctagtttac
     1981 ctggtaaact tgatccgcct ttaaaaaaag tttttaatgc ccattgcgac gtttttccaa
     2041 ctgcaatcgc aaaatgactg cgtattccca ttatgtaacc tccaaaaacg atttgctgac
     2101 gaataaattc aactaatcat accatatgtt gaaaaaaagg ttaaattgct tttcttattc
     2161 ttaagaaaag gttacggctg aaagtgcatg aaatcggaca aaatcgcatg atttaacaaa
     2221 aaaacagctt gaaacaaaat gattgtttca agctgctgtg attttattat tccctcttac
     2281 ctatattccc attttaaccg ataataattt tctcgcttgg atattcatag cctagatctc
     2341 gtgtttcttt tggcacgaat aacatcaatg tatatagcat tccgatccgc ccaataaaca
     2401 tcagtgtagc aatcgtgatt ttgcccacaa cagacaagtc tccggtaatc cctaaagata
     2461 aaccagttgt tccaaacgca gaagttactt cgatgatgat cgagatcagc gtttgttctt
     2521 ctgtagcaga taaaaaaacg atacaaaaga aacacatacc aagagaaagc ataaagacaa
     2581 cgactgattt tcgcacatca tcttgatcga ttctccgtcc aaaaatattg atgttatctt
     2641 cacttttgag gaaggaatat agatacaaac cgatgattgc tacagtagtt gttcgaatcc
     2701 cgccgcctac agaactagga ctgcatccga taaacatcag taaagaaaaa atgatcagtg
     2761 ttgtgatttg aaaatcaccc aaatcgtgaa tctgcagacc agcattacga gtcgtaatcg
     2821 aataaaacat cgaattgatc catttgacac tcatattgga atcttggaat aaatggtcct
     2881 tttccaatag ataaatcaag acagttcccg aaacaaacaa gataacaaaa gctaacacag
     2941 ctaatttggt aaacaaggaa aaacgaaacg gaagcttcgc attggaacgt ttgtataata
     3001 gccattcccg gcactccatc aatacaggaa aaccaattcc tccgacaaaa atcaaaaaca
     3061 tgatcaggat caagaaaaaa tagtcatgtg caaagggctt gatggaatcc ccagtgacgt
     3121 caaacccaga gttcgtgaca gccgatatcg cctgataaaa accgtaaaaa acggcatcac
     3181 gccaacgatc aaaatagcct ctgtaataaa aataaataga aaagaatgtc ccaaaaagta
     3241 attgaaacca gattaaaata gcaaaagtga tccgaatcag tcggacgata ccagacaaac
     3301 gcggttgatt catatccgtc atgatcagct gtcgctgttt cagtgtgatc cgtcgtttag
     3361 aaaaaatgac aaaagcagta gaaatcatca tgatccccaa accaccaact tgaaataata
     3421 tttccagcag tataataccg ttatcattga acacagaatt gatatcaaaa gtcgatagtc
     3481 cagtcacact cactgtactg attgccatga acagcatgtc cacaaaagaa acatggctat
     3541 ctggttcgcg aaaaatcggc atataaaata gaacgagtga taagaccgtc atcaatatat
     3601 aataaaaaac gatgatttgg atcgatgaga aatgattggc agcaaacttc tgtcctcgcc
     3661 gctgcagcct tcgaaagaat aaatcaacat gcacagtact atcctcctga caatagtcgt
     3721 ttctaccagt atacaagggg aattaggaat actcaaagaa attatcaaac agataacaat
     3781 acagctttcg attaaaatag aaatggctta taataaggaa aatcctagaa aaaagaagga
     3841 ggaggaataa caaattgatt aatgctcaac aaatcgtaga aaaaatgaaa aatcaaaaaa
     3901 taaattatga tacagttctg aaaaaaatga tcatgcaatg ggagaaagaa gaagtaaagc
     3961 ctaagatatt aatacataca tgctgtgctc cttgcagtac gcacacattg gaattcatgt
     4021 ctcaatatgc agagatcacg ttattttttt caaattcgaa tattcatcct aaaagtgagt
     4081 atttgcgaag attacatgaa caaaaacgat ttgtagacca atttaatgag aaaactgacc
     4141 atcatgttgc gctaatcgtt gatgaatacc gtccaaatga attcaccaaa atggttttaa
     4201 caaaccatct tgaaaacgaa aaagaaggtg gtgctcgctg cagtgcatgc ttcaatatgc
     4261 gattagatct tgttgcgcaa aaagcgcaag aactaggata cgattacttt ggaagtgccc
     4321 tgaccatctc gccaaagaaa aatgcagctt tgatcaatca gatcggaatg gatatccaaa
     4381 agatttacgg gacacaatac ttgccaagtg atttcaagaa aaacaaaggc tatgaacgct
     4441 ctttgcaaat gtgcaaagag tatgatattt atcgccaatg ttattgtggt tgcgtgttcg
     4501 ctgccaagca gcaaggatgc gatctgaaag aaatcaatcg ggaagcaaaa gcttacttaa
     4561 aaacatcaac cgtagttttt gaggaaaatt aaagaaatct ttcggaaaaa cgtaagaaaa
     4621 aaataaagaa tttatggtag aaataaggta gactgtataa tttgtccgta gtaaagtaag
     4681 gaaacaagaa taaatttcaa tgaaggaaga gataagatgc gaaaagtagc acctattttg
     4741 aagccaatcg ctgtattaac aatctcgacg attgtcgcga ctactacagg tattgtgaat
     4801 agttccagct accgtgcacc aagttcaagt tctagtactg tagaagaaac aacaccaact
     4861 acttcagtct cgacatctga accaacaaca acggaaagtt tgaatgaaac cactacgaca
     4921 agtacatggg acgatacaac aactagttcg tcgtatgatg agacatatac aactgacagc
     4981 tcaagcgaaa caagtaatac ggtaccagat ggcactccat cggattcaac caatccaagt
     5041 acaagtccgg atacaagtgc tagctccgaa acgataccaa gcagtacgac tgtagatgat
     5101 aacacgcaaa atgatgatgc agcacgtaca gcacagcaaa accaagattc aggaaatacc
     5161 caaacgtata accagcaagc aggtgattct caatgacatt tttactagac cttatcaacg
     5221 gggtgcataa attccttggc tatttagaca tcagtcctaa atatcttaac cgtggatata
     5281 cgattttaag tgtgattccc acgctttatt tattgagaat tgtttatgga ctttggcaaa
     5341 accaaaacta tcttcaattt ttcttatatg gacttgcatt tctagtgctt gtttatttta
     5401 ctgttttaaa tgtattttat tactttttag ataaaaacac gaaagccgat gtcactcagc
     5461 tttttgtgaa gtatttacct gatgaagcgt tcaacatcca gacagaagaa tcgatagata
     5521 atggaaattc gatcgataaa gtgaatacac aagaggtcat ggtttcttat gacgaagatt
     5581 atcaattgaa attagccgag aatatgcggt atttgattgg aaatggtgag atcaaaacaa
     5641 atgaactcgg tcgcatggat ggatttctgg tcgatagaaa tacattgtat ccttattact
     5701 atgtcaagaa aacaggagag aaagagtatg ttctaaatat tggacgaagc tactcggaca
     5761 tggaaaaagt agggaccatt cgacttgact caacagaaga cacattggaa cctgtcggat
     5821 tgttcatcgt cggcggtgat tttgtcaaag acgggttacg ctatcatgag ccttatcgtc
     5881 tgaaattgat tgcaaaaaag gcacagtcgc aggaagaacc agtggtttat agtcgtagcc
     5941 aaagaagaag acattcataa tgtgatgaaa cgccgtgtat cagtggttgc gataaaaacg
     6001 tttattcgga ataaggggga tgtgacacgt cttttgtcac gttccttttt tatataacga
     6061 gaaagataag acgaacacat cacttattct ttcctttcat ttataaacat tgtagaataa
     6121 agaaagtaca acgaagtatt gtgaaaaaac gtaataaata acgaggaaaa tacaagtagg
     6181 aggtaagctg tgaaagaatt tttgaaaaat tgggggattt tgatccttgt attagcggct
     6241 attttattag ctagagtgta cgtgtttaca ccagttactg taaacgggca ttcgatggac
     6301 cctacattaa gtgatggaca acgattgatt tcatctaaga tctcaaacta tgaacgaatg
     6361 gatattatta ctacaaagga accgggggat gaagaacgga tgattgttaa acggatcatc
     6421 ggtatgcctg gagatacagt caagatggaa aatgaccagt tgaccattaa tggcaaaaag
     6481 tatgatgaac cttatctgga tgagttcaaa aaagaatttt cagaagataa gttacaagga
     6541 gaatatgctt atagctcagg attccaagca caagcagaaa gttcatccac ctttacgagt
     6601 gactttgaat atactgtgcc aaaaggaaag tatcttgttc taggcgataa ccgcttgatt
     6661 tcaaaagaca gccgaatgtt tgggttagtc gacaaagata tgatccaagg aaaagttgtt
     6721 ttccgttatt ggcctctttc agaaattaaa atcatgtgat gaaaaaataa aaagaagctg
     6781 tgacatgttt tttgtcacag cttctttttc cgaaaattcc ttcttatttc ttggagttgc
     6841 tcactttttt tgcaatctca ttttaagctt tttggctgat ggataagaaa agcgaagcgt
     6901 ttttgttcat aaatagcttt tccccacgat ggaaggtatg actagtagca gagacaaagc
     6961 ccgttttttc caatcgatta ttcaattctt cttggctaaa gccattatgg actttcggat
     7021 gactaatttg ttcattcttg tcaaagtcta cgatgatcaa ttgaccgcca ggagctaaaa
     7081 tttcataaag ttttgtaaga atattctccg tatcaggaat gtgtaaaagt acaagtgata
     7141 gaaggatgag attagcttgg acagcaggaa attcgacaga agcatcagcg tggatcgttc
     7201 ggacattttt cagatctgct gcttggatct tttcttctgc cattttcagc atagtttctg
     7261 aagcatcggc aatgatcagt tctttgaatc tttccgcaag cggtaaacta acaagcccag
     7321 ttccgcctcc gtaatccagc aggacttttt ggtggctgtc gcgcggtaga taagtagtta
     7381 gttcttcgcg aataatcttg gctaatgctt gacggtcagg ggaatcataa tggttagcga
     7441 tggaatcaaa aatatttttt gtcatcaaat agctccttac gtaaaacttt gaaattttaa
     7501 cttattatag cacgtgaaaa gaaagaaagc atgctatact caattcaaaa agggagaatc
     7561 tagaaagaat atgccgatat cgtttgtaaa agatagagag gaaaaaggaa agtgtgtccg
     7621 agaaatatta ctagacttgc ctgagtggtt tgggcttcct gaatcaacgg aaaaatatat
     7681 cgaggaatca agtaaactac ctttatggtg tgaaaaaaga aaagaagaat atttaggctt
     7741 tatcactctt tcacagacaa gtgaagatac tgccgaaatc tattctattg tatgggaata
     7801 aaaaaagact atcatcacca aggattagga acaaaacttt ttaaagaagc agaaggttac
     7861 gcagcaaaac attacaaata tttgcaagtg aagactgtag acgaggggca ctactctata
     7921 tatgatcaaa ctatttgttt ctacgaatca ttaggatttt caaggttgga agtttttcca
     7981 aatttatggg atgaatggaa cccatgttta gttcttgtca aaaaattgga acaaaagtga
     8041 gcaatagatt taatactaat ctgtgcttga tgaaaattct cactgtaaaa aatgctgaaa
     8101 atcaagtata ataccatagg aacaaactgg aaggtgaaaa agagcatggc acaactattt
     8161 tttaagtatg gcgcaatgaa tagcggcaag acgatcgaga tcctaaaagt cgcacataat
     8221 tatgaagaac aaaataagcc agttgtctta atgacaagcg gtattgatac aagagatggt
     8281 ttaggcgttg tttcaagccg aatcggactg aaacgtaatg cgatgccgat atttgaagaa
     8341 acagacgtat ttgacgtaat tcagaaaatg gaaagcaaac cctattgtgt gctgatcgat
     8401 gaagcgcaat tcttaaaaaa gaaacatgtc attgctttta cgagaattgt ggacgaattg
     8461 gatattccgg ttatggcatt tggtttgaaa aatgattttc gaaacgagtt atttgaagga
     8521 tcaaaatatt tattgcttta tgcagacaaa atcgaagaaa tgaaaacaat ctgttggttc
     8581 tgccacaaaa aagcaatcat gaatttacat tatattgatg gaaaccctgt ttatgaaggc
     8641 gatcaagtgc aaattggcgg aaatgaagct tattaccccg tttgtcgaaa acattacttt
     8701 cacccatcaa tgattacaga aggagaataa gcatgtacga tcaattacaa gcaattgaag
     8761 accgttatga agagcttgga gaacttttaa gtgacccaga agtgatttct gatacaaagc
     8821 gttttatgca gctttcaaaa gaagaagcaa acacgcgcga aacagtcgaa gtttatcgtc
     8881 gttataaaga agtagtacaa ggaatcaccg atacagaaga actgcttggt gaaaaactgg
     8941 atgatgaaat ggctgaacta gcaaaagaag aattatctga attaaaaaaa gaaaaagaag
     9001 tcttagaaga aaaaatcaag atcttgcttt taccaaaaga tccaaatgac gataaaaata
     9061 tcatcatgga aatccgtgga gcagcaggcg gagacgaagc agcattattc gctggcgatc
     9121 ttttcaatat gtaccaaaag tatgctgaag cacaaggctg gaaaacagaa gtgatggaag
     9181 ctaacgttac cggaatcggt ggatataaag aagtgatcat gatgatcacc ggagacaacg
     9241 tatattcgaa attaaaatat gaaagtggtg cgcaccgcgt ccagcgtgtt ccttcaactg
     9301 aatcgcaagg gcgtatccat acttccaccg caacagttgt cgtgatgcca gaagctgaag
     9361 aagtagagat cgatattgaa gacaaagata tccgtacaga tatctatcat gcttcaggtg
     9421 ctggcggaca gcacgtcaat aaaacagcat ctgctgtacg tttgactcac ttaccaacag
     9481 ggatcgttgt tgctatgcaa gatgaacgtt ctcaaatcaa gaaccgtgaa aaagcaatga
     9541 aaatcttgcg tgctcgtgtg tacgataaga tccagcaaga agcacaaagc gagtatgatg
     9601 ccaatcgaaa atcagcagtc ggaactgggg atcgttcaga acggatccgg acgtataatt
     9661 tcccgcaaaa tcgtgtgact gatcatcgta tcggattaac tatccaaaaa ttagatcaga
     9721 ttttagcagg gaaattagat gagatcgttg atgcattgat catgtatgat caaacatcaa
     9781 aactggaagc tatgcaaaat gggtaaaatg acctatcgag aagtcctgtc acgggcttct
     9841 tcttttttag aggatcatgg gaaagaagca tatagtatcc aatttttatt tttggaacga
     9901 aaacaatgga aaaaacttga ttggctcctt catatgaacg aagagatttc agaagaagaa
     9961 cagcggttga tcgaaaccga tctgcgactt ctgcttgcag atcatccacc tcagtatttg
    10021 ctaggatatg cagattttta tgatcatcgg ttaaaggtaa ctgaagcaac actgatccct
    10081 cgaccagaaa cagaggagtt agtcgaatgg tgtttagacg agacgcctgg tgtaccgtta
    10141 gaagtgatag atattgggac agggactgga gcaattgcta ttagtttgaa agcagcaaga
    10201 aaaaattggc atatatctgc tgtggatctt tcagaagaag cattagaagt agcgaaagaa
    10261 aatgctcaga aagaaggaac gaaaatcagt ttttatcatg gagatacatt aggaccagta
    10321 atggatcagc aatttgatgt gattatttct aatccgccgt acatcagtcg gaatgaatgg
    10381 gaactgatgg atgaaagtgt ccggtcattc gaacctaaaa tggccctttt tgctgagaac
    10441 gatggattag ctatttatga aaaaatagca gttgaagcac caagcgtact aaaatcaaat
    10501 ggaaagattt ttttagaaat cggatttcgc caaggtgaag cagtaaaaaa aatatttcag
    10561 caagcatttc cagataaaaa agtggcgata aaaaaggatc tttttggcaa tgaacgaatg
    10621 atccaagttt atggttgaag ttgtggatga aaaatttttt atttgttttt ttattataaa
    10681 aaaacactta tttgacaagg atgtaaacga ctttttggtt tatcaacaag tttatccact
    10741 attgacaaat agattatcca caaacagtgg aaaacttgag gataaactca gacaaaataa
    10801 gaatgtatga aaaaggggtt gtggataaac tgtggaaacg aaacgatatg atgaaacaga
    10861 attgcaagag gcagccgaag cactgaaaga aggagaactt gttgcttttc ctaccgaaac
    10921 agtatacgga ttgggcgcca acgctctttt accaaacgct gtcaagaaag tgttttctgt
    10981 aaaagggaga ccgcaagata atccattaat cgtccatgtc gcctcttttg aacaagtaaa
    11041 agagtatgtg gacaactttc atccggcagc agagaagatt gtgaagaact tctggcctgg
    11101 accattaact ttgatattta agatcaaaaa agacactttg ccctcagttg tgacgggagg
    11161 attatccaca gctgcatttc gtataccgga taacaaaaaa acactagaag taatcgaact
    11221 ttccggtgtt ccgcttgtcg gtccaagtgc aaatacgtcg ggaaaaccaa gtccaacgac
    11281 tgcagatcat gtatatcatg atctacaagg aaaaattacc gggattattg atgatggagc
    11341 tacgcgaatt ggtgtagaat ccactgttct tgatttaagt gatccaacag ccatgcctat
    11401 gattttacga ccaggtgcag taacgaaaga acaaatcgaa gcagtcatcg aatctcctgt
    11461 tgctattgat cagcatcttg taaaagaaaa tgaaacacca aaagcccctg ggatgaaata
    11521 caaacactac tcacccgata cacgtgttct gatggtcaga gatggcgatt ggtcaactgc
    11581 agttcaatgg gcaaaaaata agaagatccg tgcaggtgtc atagcaagcc ccgaaattgc
    11641 ggatcaagtg cggacagata ctgcagctgt ttatatgtat aacgacaact cagtagaagc
    11701 ggcggctaaa ggattgtttg caggtctaag aggattagat gaaccaacac ttggattaga
    11761 tttgattttt gtacaagtgt atccagaaac tggattgggg aatgcttaca tgaatcgctt
    11821 gaaaaaagca gcaggacaaa attattttga aaaatgatca attggttatt gtcgcattct
    11881 tttagtatga tacaatgcta tcaagtaaat cttctatcag tgaacgaaaa actaagcgta
    11941 actaatcgta atagaagaga tacgaatatt tggcaatttg tttttgatgg gaaaaataaa
    12001 attgtaggaa aataaaaagg agctgttgtt tgtggtagat tacaaaacgt ttgaccctga
    12061 tctttgggct gcgatcgcca aagaagaaga aagacaagaa cataatttgg agctgattgc
    12121 ctctgaaaac tttgtctccg aagcagtgat ggctgcacaa ggaagtatct tgacaaataa
    12181 atacgcagaa ggttatccag ggcatcgcta ttatggtggg tgtgaatttg tcgatatcgt
    12241 tgaaaattta gcgattgacc gtgcaaaaga attattcgga gcgaaatttg cgaacgtcca
    12301 gcctcactcc ggctctcaag ccaacacggc tgcttatctc gctttggtag aaccagggga
    12361 cacgatctta ggaatggatc tttccgcagg cggacatcta acacatggat caccagtcaa
    12421 cttcagtggc aaaacctatc actttgttgc ttacggtgtt gatccgacaa cagaagttat
    12481 tgattataat gtggtacgta ttttagctag aaaacatcaa ccaaaattga tcgtagcagg
    12541 tgccagtgct tacggacgaa cgatcgactt tgcgaaattc agagaaatcg cagatgaagt
    12601 aggcgcaaaa ctgatggtag atatggcaca tatcgcagga ttagtagcag caggacttca
    12661 tcctaatcca gttccttatg cagatatcac aacgactacc actcataaaa cattgcgtgg
    12721 ccctcgaggc ggcatgattt tgacaaacga tgaagcatta gcaaaaaaaa taaatagtgc
    12781 ggtatttcct ggtattcaag gcggccctct agagcatgtg attgcgggta aagcagtagc
    12841 attcaaagaa gcattagatc ctgcatttaa agaatatagt gaacaaatca tcgccaatgc
    12901 aaaagcaatg gtcaaagttt tcaatcaagc aattggaacc agagtcattt caggggcgac
    12961 agataatcat ctgatgttga tcgatgttcg cgagttaggt ataaatggaa aagaagcaga
    13021 gagcattttg gacagtgtga atatcactgt aaataaaaac tcgattcctt ttgaaacact
    13081 aagtccattc aaaacaagcg gtattcgaat cggcacgcca gcaatcacta ctcgcgggtt
    13141 caaagaagaa gatgctgtaa aagtggctga actagttgtc aaagcattac aagcaaaaga
    13201 tgataacgct caactagacg aagtcaaaac aggtgtacgc gaattaactg aaaaatttcc
    13261 gttgcataaa aaataaaaat ttaaattcca ttagtaaaca gaaaagttca atgttgggct
    13321 tttctgttta ttttttggga aaacggattc tttgacaata tcggtgatgc tctctagtat
    13381 atgaggtgta attttagtct tcacactaaa tctcagggag gaaaagtcat gactgatcgt
    13441 atctcgttag aaaaggaagc agtagcattc agtgatgcaa atgcgcctca tccgcgtatc
    13501 tatgaactag caccggaaga aggaagagtt ttactagaag aagtacaaga atcacctgtg
    13561 aacaaatatt ccgtcgatat tgaagacttg atggtggata ctggcgaatg gggaaaactc
    13621 aatattcgtc tcgtacgacc agaagggaat atggataaat taccagttat tttttatatt
    13681 catggagcag gctgggtttt tggcagtgct caaacccatg ataaattgat cagagaactt
    13741 gcggttcgta cgaattccgt cgttgtcttt ccagaatata gtcgatcacc agaagcaaaa
    13801 tatccaacag caattgaaca aaattatgct gtgttgcaac agctgaataa attagccaag
    13861 tcaaaaaatc tggatctcga gaatctaatc gttgcaggag attcagtagg tggtaacatg
    13921 gctacagtca tgacgatctt aacaaaagaa cgaaagggcc tcccaatatc caagcaattg
    13981 ctgtattatc cagtcacaaa cgctgatttt gatacagatt cctatcatga attcggagaa
    14041 aactattttt tgacaagaga aggaatgatg tggttttggg accaatatac gacgaatgaa
    14101 gaagagcgtg ctgaaatcac agcttcgcct ttgagagcaa atataaatga actaaatgat
    14161 cttccttcag caatgatttt aacgggagaa gcggatgtat taagagatga aggtgaggct
    14221 tatgcgcgca aacttcgtga tgcaggggtt cctgttacac aagtacgctt ccaaggaatc
    14281 atccatgatt ttgtcatggt aaatgctatg gatcagacaa aggcaacgcg tgcagcaatg
    14341 gcattatcta cttcttggat caagaaaaaa gaataagctt tgcttgtccg caggaaaact
    14401 tcttttcaaa aacggatttt cttaggaaaa atggcgagtt tgactagtca atcacttgat
    14461 tttgttttac aattaaaaag aaacgacaga acaaaggaga gcttaaaaaa tgggcaaatt
    14521 tcaagtgatc gatcatccat tgattcaaca caaactaact attattcggg acaaaaactg
    14581 cggaacaaag gtttttcgtg aagtagtcga tgaaatcgct atgttgatgg catatgaagt
    14641 atcacgggat atgccattgg aagacatcgt gatcgaaaca ccgatcactg aaacaacaca
    14701 aaaaacgttg tctggtaaaa aagtagcgat tattccaatc ttgcgcgcag gtattggaat
    14761 ggttgacggt atcttggaat tgattccagc tgctaaagtg ggacatatcg gtctttatcg
    14821 agatgaagaa acattggaac cacatgaata tttcgtcaaa cttccagaag acattgatgc
    14881 acgtcagttg tttgtagtag atccaatgtt ggcaacaggc ggatcagcaa tcatggcaat
    14941 cgatgcattg aaagaacgtg gcgcgtcgaa cattaaattt gtttgtttgg tagcagcacc
    15001 tgagggagta aaagctttgc aagaagcgca tcctgatatt gacatctata cagcttctct
    15061 agatgaaaaa ttgaatgaac atggttatat cgttcctgga ctaggggatg cgggtgaccg
    15121 tttgtttggt acaaaataag taaatacgaa aaagggtgtg acacaacttt tgtcacatcc
    15181 ttttttggtc atttttaacg tttgatgcag aacagctttt tcacagcttt cgtttgcata
    15241 taaaaaaacc atcccaaaaa tgcagagatg gtcaaattca aatctttttt agttctttgt
    15301 agttaacgat tactacaccc ttactttgcg tcatcaagtt cgcattttct gcagtttcat
    15361 caatctcaac aacagcggaa tttttcaatt gctttgaaat cgttccagtt tgcgacttgc
    15421 cgtgaattgt gaacattacg tgagtattga tcttgaattt ttcaccaatt tccgatggta
    15481 cgatagttgt atcaaatttt ccaaaagttg ccattttcat aaaacctgcc tttcacatca
    15541 attataccac gttttatgaa aaatatcatg aaattaaact aattttccat cggactcttt
    15601 acaatcagcc aaatagagta tataatttct tttggataag gccagcttag ctcagttggt
    15661 agagcaacgc actcgtaacg cgtaggtcgt aggttcgatc cctatagctg gcattaaaag
    15721 agaagacaga tatatcaagg atttttaatc cattgataca tctgtctttt tgtttaaagg
    15781 aaataaagta tgctttctta gcaatagagc atgtattatt tctataaaaa tttaggagaa
    15841 taaaacgact agcaatatag ctgtgaaatc aaatatcaca tgaactgccc aacttgtaat
    15901 gatcgagttg cttttaatgg cagcttggtt gaataacaat cttgccaccc cttgtatcaa
    15961 aaggatgtgt gctacagtgt gtaaaatatt tccattatca taagtactgt aatggataaa
    16021 tccaaagatg attgctgaca agaaactagc gacaggaatg ctgaacttac tagaaaaaat
    16081 agcgagaaaa tacactgaga acaattcttc tccaagtatc atgataggca aaataataaa
    16141 taataacggg ctgaaagcct catttattgg attgcctgtt aaaccccatt tcaaaatttg
    16201 ttgcaaaaat accgagactg cggcactgat tactacattg ataaaaaaat atttggctat
    16261 atttttgaca ggagcgacag gtttcgagaa catttttttc gtatcttttt taccaaaaac
    16321 aagtgtaaat gctataaatc cagtgatagt taaagaaaaa atgctaataa tggatggcgc
    16381 aaatagcaac cctaacaaac cgagtacaac gacaatagtg cccaatatcc cttttttaag
    16441 ttctattttt tttcctaaaa tgttattcat gataataact cctactattc agtttttgaa
    16501 gatagagtca gtatacatga agagttaaaa taggcaatgt ttttttatgg atatttgtat
    16561 tgctaaaaat ttatcttata tattcatttt gattatacta cttttatttg taaaaatttt
    16621 ctagcaaaac caagtgcttg caactgatta agcgtacaat tttttagatg ttccgagcgt
    16681 acttcaatca tttcaaagga gttgctactt aaatcgatat tttttaaatc agtatcaaaa
    16741 aagctagcat tttctaaatc attagtagaa aacattattt tagtgaggga acagtctaca
    16801 aaatctgcgc ttgataagac agagtgctca aaggtacttt cttttatgtt tgaaccagat
    16861 aaatttacat agtccatttt acaattctcg aataacgtgt tcccaatata actttccatc
    16921 aatttagtac ctgttaattt acaattgaca aatttcacgc gatgcaacat gctttttgtc
    16981 aatatacagc ctgaaaaatc acagttttcg aatatacagt cggtaatctc cattctttga
    17041 aaatcattgg aagcaaaaaa tgcatacttg aaaatagatt tgtaaataat tggatggcag
    17101 attatttggt tttcgatgac ctctttttgt gaaaggatat tatacagttc aaaatcttcg
    17161 ttttcataga tatgaaaaaa ggatccttta ttcaagcttg cttcattaac tttaggaaaa
    17221 atcatattta attacctcca ttttcataaa gtcatattaa caaaagctaa accaacttac
    17281 attagcagaa aatgagatag gttttcgcct ttttcgataa cgatagtgtc gctatctctt
    17341 gaaacgttct tagaattgcc ctgagagaca caaattaggc gtaattctaa taaaaatctt
    17401 agaataaaaa tttttactga tttaatttag aatgttttta aaataaaaat cgttgccata
    17461 acagtgtatt gaaaggtttt aacaatccag taatgattta aaaaaatcta gatgtagcgt
    17521 atactttgtt tatagaatgt agtgggaaga aatatatttt tgggaggaaa tcgtgatgtc
    17581 taaaagtgaa gaaatagaaa acatggtact aaaattatat gatctcgttt taaatccaga
    17641 gatcaaagaa aaggaacgta tacttttgat agacgcaaag acaggcttag aaaaaggtca
    17701 gtattatcct aaagtcataa ataatttgga acgtagttta cgtccgttag caatcagggg
    17761 agaattgtct aaaccagtat caccgtttta tatggagata tcaacaatag gaaaatttga
    17821 aaaagaatta ggtcgaggaa tggcttcggc accgattact tttgggcatt tataaaaacg
    17881 agttattcat ctcaatgaat taaaaagtat agtcaatctc ataatgcagg ctaggttcat
    17941 ttatttgaac agagtctgta tttttttatt ctaaataaag aaacagatgt ttctttatat
    18001 tgtattttat cctttaatta acacaaaaac agctagtata aactaataat gttaattaaa
    18061 agtgtatttt atgaaactat cgttatttat taatgttgca tttttgtaag ttaaaaattg
    18121 gaaatataga ttgaaaaaat gaaagcaata agtaaaataa aatgaatata tgcgaaaaaa
    18181 taatttacat taggaaaaac cttgtaaaaa cagttttttg gcatatttat tttttataaa
    18241 tatttgtaaa ataactatca attttttagt taaaagattg gaaatgagtg ggggaggaat
    18301 tgaagaaagg atttttgaga gatgatatag taggttttat ttttagttaa aataggggag
    18361 atagaaaaaa tgaaaaagtg tagaaatatt attttatcaa tgttatttat tattactaat
    18421 ataacatcac tgattcctgt tcatgtctat gcggatgcag gcagagatat cagcagtaat
    18481 gtcacttcgt tgaccgtgga cccaacgaat attacagatg gaggaaacat aaaagtaaaa
    18541 ttctcgtttg acgaaaaaaa acaaaatatc caaccaggtg attatctttg gatcaattgg
    18601 ccaagtgaag gaaatattcg cggtgaagga ttccaaaaag aaatcccatt aatgattgaa
    18661 aataaaaatg ttggaacttt aacggtcaga aaagattctg cgcaggttgt gtttaatgaa
    18721 aatattaaaa acctagactc agtagaaggt tgggggcaat ttgagataca ggccagaaac
    18781 gtaaccgata ccggtgaaga aaatacggga ccattcaccg tgacgagcgg tgataaaaca
    18841 gctactgtaa atgtgacaaa gccagcttct ggttcttctt ctagcgtttt ttattataaa
    18901 acaggagaca tgctacctga agatactaag cacattcgat ggtttttgaa tattaacaat
    18961 aacggcactt atgttgaaca accagttaaa atcagtgatg aaatccaaag tggacaaaga
    19021 ttagatccaa gtacgtttga aattaatcaa atacacttag gtgaacagaa ggtttataga
    19081 ggagaagagg gaatccaaca atttttacaa gatttcccca gcgctacatt taatttttca
    19141 gtaactgata attacattga aataactata ccaaaaaact ttgtcaatct taggaaaata
    19201 atggtgagtt ataagacgat catagaaaac ccagaacaaa taaattttga gaatcattcg
    19261 gaagcttggt ttaaagaatt taataaacct gctgttgatg gagaaagttt caatcataca
    19321 gttaaaaata tttcagcttc tggtggagtc aacggtacag ttagaggcga attgaagatt
    19381 ttcaaatata tcaatgacac agagattggt atcccaaatg tgactttcga attaagacga
    19441 gcagatgaac agcctattca aggacagtct agtatcctgt tgacttcgaa tgaacaggga
    19501 gaagctagta tcaaaggcct gcaagtagga gactatgttg taaaagaaaa agaagcaccc
    19561 aattggattg attttgatcc actaagttca aatgaactca aattctccat aaacgaaaat
    19621 gatacagagg gagtcagttt acctatttat aacaagaaaa aggttacgaa catcacagca
    19681 actaaaattt ggaacggtgg aaccactcca agaccgagta tttattttaa attattcaga
    19741 gcaagtacaa acaattggga accagttcct gatgcagaaa caaaacgatt agacaatgga
    19801 ataacttcag tgacttggga agatatccaa cagtatgatg atagtggaaa cgaatatacg
    19861 tttaaagtgc aagaagtaga tcaaaacgga aatgattatg tcccttcagg ttatcaaaaa
    19921 attgaaaacg ggctagtcgt tacaaatgag aataaagaag tcatttcagt ctcaggacaa
    19981 aaaacatggg aagacaatga gaaccaagac ggcaaacgac cgacgacgat cacagtaaat
    20041 ctattagccg acggtcaacc gatccaacac aaagaagtaa gtgaaaaaga tgattggcgc
    20101 tatcgtttca caaatctgcc aaaatacaga gacgggcaag aaatcatcta tactgtaacg
    20161 gaagacaacg tgcccgaata cagtacgacg attgacgggt ataacatcaa aaacagttat
    20221 acaccggaaa aaacaaatat atctatacca ggtagccata taacaccgtg gaaaaatttt
    20281 ccagagaaga cagagagaga gaaaattaga aatctattct ctcaaaaatt gcaaatattt
    20341 gctcatacag gagaatccag cgaacaaaga agcaattata ttagtaagag agctgtacct
    20401 aaacagataa caaataaatc aaaaagcatt cttcctaaaa caagtagtaa aaaatctagt
    20461 tttgctgtaa tcattggttt attgatagta actatctgtg ctgggatatt cttacaaaaa
    20521 tataaaaaag tttagttaga atataatatt ttttgttaaa tatgactgaa atcaaaagaa
    20581 taaaattccg atttataatc gaaaaaagaa gcatttttat atatgcttct tttttcgtag
    20641 aatcaataaa tatggatttg gctaactatg gaagaatact cgtattagtt ttcagcgttc
    20701 atactagttg ttacattgtt tgattggcca aaagaatttc tgatatattt tgtgctaaat
    20761 aaagaaaaag acgcttgaat tgggaaataa gaaaactact ctatcattac aaattttcat
    20821 aaactggcag atgttctaag taaacaagta tcttttcaaa gtcggaaaaa tccataatca
    20881 acgtagtggt attgatattt ggatgaaagc ctacggtatc ttgacgatca atagcagcat
    20941 cgatcacgac ttggattttt ttctctttgt cgtgcatcaa tgctaatgga gtcactgtac
    21001 ctgctggaac gcctaggagg tcaggaagct gttcttcaga aacaaaagat aagcgctttt
    21061 cttttaattg ttcagctagt tgttttaaat cggcgtgctt ttcatcaggc aagatgacaa
    21121 gatagatttg ttttcctttt cttgatttca ataatagatt ttttacttgc ggaccaggta
    21181 gggaaaaagg gacatttttg actgacgtaa tcgcaggatg atcgactttt tgaaaagaga
    21241 tacccagttt ttttagtagt tcataagctt cttgttcggt tgcacgactc atcgcgcatc
    21301 accctccttt ttttattagt gtatcataaa aaagagttga caaatgaaaa ataatcatgt
    21361 aaattacacg taaagttaaa acaaatgaca tcgaaaagaa gagtagccgt taggtgtttt
    21421 tagagagtct ctggttggtg gaaagaggca gcagttaacc gtgaaacaca tcttggagtc
    21481 gattttctga agcgtatagt aggaaaatcc ggggagcccg ttacagctgc ggtcgttgct
    21541 agatgaccag ataaggctgg cttttccgtg aggagtcggt aaaaaaaggt ggaaccacgt
    21601 gattaacgtc ctttgatctt cggatcaaag gactttttgt tttcatctga acggcaacga
    21661 ctgtgtgagg ttttttctgc aaggaaaaaa taaacagagg tggaaccacg tataatacgt
    21721 cctcttggca tttgccaaga ggattttttt attttaaagg aggaaaagaa gatggagtat
    21781 ttgattgaag ttatgccgca attattagta ggagcactca caacattgaa attattttta
    21841 tttaccttga ttggctcatt accattaggg attgttttag cattaggatt gtctttgcat
    21901 tttaagccgc tacgctactt gcttcaaaca tatgtatggg ttatgcgggg aacaccgctg
    21961 ttgttgcaac tgatttttat tttttatggg ttgccgacga ttgggatcgt ttttgatcgt
    22021 ttcgaagcag cactcattgc ctttatctta aactatgcag cttattttgc agagatcttt
    22081 cgtggaggga tacaatcgat tcctcaaggt caatatgaag cagcgcaagt tttgcaatta
    22141 agtccctttc aaacggtgac gaaaatcgtc atcccacaag tgacaaagat tgttttacct
    22201 tctgtaggga atgaagttat caacttggtc aaagattctt ccttgatcta tatattaggt
    22261 ttaggtgacg taatgcgtgc tgggaaaatc gcgatggaac gcgacgcgac tttactgcct
    22321 ttgctaggcg tggcaatcat ctatcttaca ttgactggta ttctaacaat cataatgaaa
    22381 caagttgaag gaaaattaaa ttattaccgc taactgatag gaggaagaaa tatgattgaa
    22441 ttgaagaaag tgaacaaagc atttggtgaa aaaaaaataa tcaaagattt gaatctaatc
    22501 attccagatg ggaaaacatt agctatcgta ggtccttccg gtggcggtaa aaccacgctt
    22561 ttacgtatct tggctggctt agaaagttct gacagcggag aattttattt agacggtgta
    22621 ccgttcaacc cattcgagct taaaatgaaa gaacaagttg taggagtcgt attccaagac
    22681 ttccagctat ttccacatct gaatattttt gaaaacatta ccttagcacc aaaaatggta
    22741 ttgaaacaga caaaagaaga atacaccaaa aaagcagaag aattagcggc ttcattaggg
    22801 attagtgatt tattgaatat ctatccttat cagctttctg gcggacaaaa acagcgggta
    22861 gcgattgcca gagcattggc tatgaatcca cgggtattgg cttatgatga accaacaagt
    22921 gctttagatc ctgaattacg ccagcaagtc gagcgtttga tcctatcatt gaaagaagat
    22981 ggggtaaccc aaattattgt cacccatgat ttagtatttg cagaaaatgt cggtgatcaa
    23041 ttactaaaag tttccccaat tcattaagaa aggagaagat agagatgaaa aaaaccagtt
    23101 ttctattcgc tttgatcgca ggtcttcttc tttttgcagg ctgttcgaac aaaaaaactt
    23161 cagcagataa ttgggcgact atcaacgaag agaaaaaaat cgttataggt ttagacgata
    23221 catttgttcc tatgggattt agagataaag acgggaagct cacaggattt gatattgatt
    23281 tagccaaagc agtctttgaa caatatggga ttacggtaga ctttcagccc attgactggt
    23341 caatgaagga atttgaactg aacaatggaa cgatcgattt gatatggaac ggctattcca
    23401 aaacgccggc aagagaaaag aaagtgcaat ttacaaaacc ttatatggaa aacgatcaag
    23461 tgctgatcac acctaaagaa tcaggaatca caaactttgg acaaatgaat aataagagat
    23521 taggtgcgca aaatgggtca tctggttatg atgtatttac gaaacaacca gaagtattaa
    23581 aagagatagt caaaaaccaa gatgctgttt tgtatgatag ttttaatgaa gcattgatcg
    23641 atctgaaaag cagacgggtc gatggtctgc tgatggataa agtatacgca gactattatt
    23701 tgaaacaaag aaacgaacta gaagacttca acataacaaa aggttcttat gagagtgagg
    23761 attttgcagt tggtgcacgc aagtcagata gtacattagt gaaaaaaatc aatgaagccc
    23821 tagatcaact agagaaaaca ggtgaattcc aaaaaatatc cgataaatgg tttggcgaag
    23881 atgttacgcc gagaaattaa caaatagggg actgtgacaa aagacgtgtc acagtccctt
    23941 tttccgaata aacagtgttc tcctgccaac tccttgtgac tcggagctga atggcaggct
    24001 cacaacctct tggtaaacgg tgttcaaaag ccagtttttc ggtattaagc caaatttatg
    24061 caaaaatgta gaaagccatt ttcacaaaat ttttcttact actcgaaact aagcgacttt
    24121 ttcacaacct cctttacata attttatttt gttgtggaag gggtttcgtg ttattctaaa
    24181 agaggaacga ttgaaggtta taggaaagga agagatgaat ggaacacaaa gaacttacct
    24241 catttccaaa agattttctg tggggctctg cttctgcagc gtatcaagta gaaggagctt
    24301 ggcaagaaga tgggaaagga gaatcagtct gggatcgatt tgtacggata cctggaaaga
    24361 catttaaagg aacgaacggt gatttggcag tagaccacta tcatcgttat aaagaagata
    24421 ttgctttaat gaaagaacaa ggtctgaaag cttaccgctt ctctgtagct tggacacgga
    24481 tttttcctaa tggacgagga gaagtcaatc aagctgggct cgctttttat gagagattga
    24541 tcgacgaatt gattgaaaac gatattgaac ctatgttgac tttatatcat tgggatcttc
    24601 cacaagcatt gcaagatgaa tataatggtt gggaatcacg tcagatcatt gaagatttca
    24661 ctcattatgc agaaacatta tttgaggcat tccgcgggaa agtccattac tggattagtt
    24721 tgaatgaaca aaatatcttc acttcattag gttatttgtt agcagcacat ccgccaggtg
    24781 tgacagaccc gaaacgaatg tatgaagtta accatattgc taatttagca aatgcatctg
    24841 tcatcaataa atttcacgag ttagaaatgc ctggaaaaat cggaccaagc tttgcgtata
    24901 cgccaaatta tccaattgac agtaatcctg aaaatgttct ggctgctgaa aatgcagaag
    24961 acctgatggc caattattgg atggatgtct atatgtgggg aaaatatccg attgctgcca
    25021 tgaggttctt agaagaaaaa ggatgggcac caacgattga agctggcgat gcagaattgc
    25081 tagaatctgc taaaccagat tttcttggga tcaattacta tcaaacggcg acgaatgcat
    25141 tcaatccatt aaacggagtt ggtgctggaa aaatgaatac gacaggaaaa aaaggttcat
    25201 cagaagaaac tggagttcct ggaatgtata aaaaagttga gaatccattt gtcgaacgaa
    25261 caaattggga ctgggagatt gacccagaag gattaaggat cggactgcgt cgtatcacaa
    25321 gccgttaccg catgccggta ctgattacgg aaaatggctt aggagagtat gacaagttga
    25381 cagaagataa acaaatccat gacgactatc gaatcaatta cttacaaagc cacgtcaaag
    25441 ccatcaaaga agcaatttcg gatggagcag aagtcctagg ctattgcacc tggtcttata
    25501 cagatttgct tagctggctg aacggttatc aaaagcgata tggatttgta tatgttgatc
    25561 aagacgaaac acaagaagga tctttggaac gatataagaa agacagttat tactggtacc
    25621 aaaaactgat tgaagaaaat ggagagaacc tttagttcac atacttaaaa caagaaggta
    25681 cggctggata tggccgtgcc ttttcttgat aaaatcattt agaaattaag aaaaactgta
    25741 aaataagctg aaaaatgaaa gaaagcgtca gttctttcaa acaaaacttt agttccctta
    25801 cttttttttg tataatgaaa cttgatgaaa tgagggataa taaatggcac aaaagaaacg
    25861 gcctactaaa aaaaggaaaa agacgaaaaa aacgaaaaag caaaaacagc agcaggaaca
    25921 aatgctgacg attggtgttg ggtttgcctt gattttattt gctgtcttcg gctttttaaa
    25981 attaggtttt ttaggaatat tgattgcaaa cggctttcgg atcattgcag gaaatactta
    26041 ccaaatcctc tgtcttttat tagccgtatt aggattttgg attgtcatta agaatacaga
    26101 gttttcaatt ggtaaaaacc gacgctggtt tggcggcata ctcttttatt tcggtatctt
    26161 attattgtta catgcccatt tatttggcaa actccatact ggggaaccaa atatcatggg
    26221 gacgacatgg gatttgttag ccagtgatat aaaacaaagt caagtagaca ataacgttgg
    26281 tggtgggatg attggagcaa tcctttatca ttttacttac ttcttgattg cacagcctgg
    26341 aagttattta gcagcagtgc tattactggc aggaggagca ttcctgttca gtaatctgga
    26401 aggctatcag ctgttaaatg gtatccaatc aattggagaa cgagtacagg aattattgga
    26461 aggtgatcct gccaagcaag ctcgaaagca agcggcaaag gaagagagaa tgaaacagcg
    26521 cgcagaagcg aaagaagcaa ggcgcttagc tgcaaaagaa gctgcagaaa aagaagctgc
    26581 agaatatgag aagaaaaaag cggtgagcca gcaaagggaa aatactgctg atgaatggca
    26641 ggaaccagaa aatacagagc cggagcagct aagttttgtt ccaatcgaca gttttcaaga
    26701 aaatatccat cctgcgaatc tagagaaacc agtaccagat acaccaaaac agaccaatac
    26761 agcagaaggt ttttcagatg agttgccaga ggatgacggt acctcattag aatttgagat
    26821 tgaagcagaa caggaaaatc aagactatga attaccgaca gttgatttgc ttgattctat
    26881 accaactgtg gatcaaagtg atgagtataa aaaaattgaa aaaaatatcg gcgtattaga
    26941 acaaactttc caaagtttcg gtgtcgatgc caaggtcgtc aaagccagct taggaccatc
    27001 cgtcacaaaa ttcgaagtcc agccggctgt aggggtaaaa gtaagtaaaa ttgtgaactt
    27061 aacagatgat atcgcgcttg ctttagcggc gaaagatgtc cggatggaag caccgattcc
    27121 aggtaaatca ctgattggta ttgaagtacc aaatggaaag atcagtatgg tttcctttag
    27181 agaaatcatc gaagcacaac caaaccaccc agataaatta ctagaagtac ctttaggacg
    27241 tgatgtttct ggacgggtac aaacggctga tctttcgaag atgcctcact tactcgtggc
    27301 tggttcgact ggtagtggga agtcagtagc aattaatggg attatcacaa gtatattaat
    27361 gcgtgctaag ccccatgaag taaaactgat gatgatcgat ccgaaaatgg ttgaattgaa
    27421 tatgtacaac ggcatacctc atctgttgac gccggtcgtg acgaacccta gaaaagcagc
    27481 gcaagcctta caaaaagtag tacaagaaat ggaagaacga tatgaaaaat tcgcggcaac
    27541 cggagtaaga aatatttctg gttacaatga atttgttcaa cagaaaaact tggaaaacgg
    27601 aacgaaacat ccaaccttac cattcatcgt agtgatcgta gatgaattag ctgatttgat
    27661 gatggtagcc agcaatgaag ttgaagatgc gattattcgt ttagcgcaaa tggctcgggc
    27721 agcggggatt catatgatcc tagctactca acgtccaagt gtggatgtta tcacaggaat
    27781 catcaaagca aatgtacctt ccagaatggc atttgcggta tcaagcggta cagattctcg
    27841 gacgatcatt gattctaatg gggcagaaaa gctcttaggg cgaggagata tgctattctt
    27901 gccaatgggt gagaataaac cgatccgtgt gcaaggagca ttcatttctg accacgaagt
    27961 agaacgggtc gttcaatttg ttacagatca gcaagaagct cattatgaag agaaaatgat
    28021 gccgacagat gaagttgaaa cgacaggtgc tccagaacag ccacaagatg agctgtttga
    28081 agaagcaaaa gcacttgtcg ttgaaatgca aacggcaagt atttcccttc tccaaagaag
    28141 atttcggatc ggttacaacc gagcagcacg tttagtagat gaactggaag ctcatggagt
    28201 tgttggcccg tcagaaggaa gcaagcctcg gaaagtattc attgagcagg aagaaacatc
    28261 agaaacgttg ccggacgata atgacatgta aaacttgtgt gatgaagggt tgaaaaacga
    28321 ataaccaata aaaagacaag gcatgatgat accaaaagaa aaaatggttt ttttccatct
    28381 tttctaatac ggtatgatgt cttgtctttt tagtttttgt gagattaaag ttctattcga
    28441 tttatttgtg aagtattgca ttaaggaaat gaatcatgta tagtatgtag cgaaactttg
    28501 agaaaaagag ggaaaatact ttggaaaaac agtccattta tggcttgacg aatgaagaat
    28561 taatcaattg gtttatagaa aacggcgaga aaaaattccg agctgcccaa gtttgggaat
    28621 ggttgtatca aaaacgtgta agtaatttca cagaaatgac gaatctatcg aaacaattga
    28681 tcgaaaaatt atcggagcat tttatcatca atcctctaaa acagatggtc gtccaagaag
    28741 cttcggatgg tacagtaaaa tatttgtttg aactccctga taaaaacatg attgagactg
    28801 tactgatgag acaagaatat ggcttgtcag tttgtgtgac gacacaagta ggatgtaata
    28861 tcggctgtac gttttgtgca agcgggctgc tcaaaaagaa ccgtgatctg actgctggag
    28921 aaattgttgc acagatcatg atggtccaac attattttga tgagcgcaat cttggcgaac
    28981 gcgtttcaca tgtcgttgta atggggatcg gtgagccatt tgataattac gacaatgtaa
    29041 tggacttttt gcatatcatc aatgatgcca aaggattggc aattggtgct cggcacatta
    29101 cagtttccac tagtggatta gcacacaaaa tcaaggaatt cgctaataac ggcttgcaag
    29161 tcaatctggc tatttccttg cacgcgccga ataatgaggt gcgaacatcg atcatgcgga
    29221 tcaaccgaag tttcccaatt gagaaattga tggaagctgt ggatgagtat ttagagaaaa
    29281 caaaccgtcg aatcacgttt gaatatatca tgttgaatca agtaaatgat agaccagagc
    29341 atgcgcaaca attagcagat ctattaaaag ataagaaaaa attagcatat gtcaacttga
    29401 ttccatataa tccagtcagt gaacatgatc aatattctcg cagtccaaaa gctgatgtat
    29461 tgagatttta tgatgtattg aagaaaaacg gcgtaaactg tgtgatacgt aaagaacatg
    29521 gtacagatat tgatgcagct tgcggacaat tgcgaagcaa gcaaatgaaa aaaacagttg
    29581 ccaaataatc gtatcctact cgttttttca attaccataa aaggagcagt tttcttaatt
    29641 aaggaactgt tcaacttaaa taagagaaaa gattctatag cgaaagctat aaagcttttt
    29701 ttgacaagaa aaaccctcat caagcaaaga aatgtcctca atttgatgac agcctgcttg
    29761 atgggggttt tagcaattat ttaactgatt ttcttatatc cttgctggct ttcttgtgta
    29821 gcatgataag tttctacgtc aagaatggcc tgtttaaatt tttctcgggt gatttcataa
    29881 ggcacatgtt taatatcatt tgttgccatg gctttatcta agattgcttc taaatcggtc
    29941 gtgacattga gattcatgtc ggttaacgat actggaagtt ggttcttttt cataaacaca
    30001 tagattttat caaacaaatc gaactgctga tccatcatca ataaggtcag tacaccataa
    30061 ctgacagatg ctccgtgaag gtatccctcc attttttcta gaacagtcgt accgtaatag
    30121 aatgagtgtg ccatagcaga attatagtta ttgttaacta aaacagaaac caatccggta
    30181 gtaacaatga tatccgaaac gacttgttca attgcatatg agggacgatc gtcggcacta
    30241 tctttcaatg cttgcgtacc ataagtcaag agacgatcaa tgcacatttt tccgatttgg
    30301 attcctaatc tatccgtgta gcctagatca tcgccacgag cagaaaaagt agattcgact
    30361 tctttggata aagcatcgcc aatacctgcc cataagtatt tatcaggtgc ttcggcaata
    30421 attgctgtat caatgaaggt gtgtacaggt ggttttgaag gaaagaagag tccgtccatt
    30481 acgccttctt cgttatagat gacacatacc gcagtgacgg gcgaacagtt cgaaccaata
    30541 gtgggaaagg tgaagactgg tttagctagt ttttcaccaa tgacttttac agtatcgcaa
    30601 gcacggccac caccgactgc aaacaggacg tctgcttttt ggacactttc atgctggatc
    30661 aactgttcaa tatttccata agttgaatta cccccgtacc agagactggc gacaacctct
    30721 atttcctgtg tcaaagctac ttttattttg ttttctgcct ttgaaagtgc agtcttccct
    30781 ccaatcagca ctacttttgt cccatattct ttgacgattc catttgcttt ttcatacgca
    30841 tctgttccaa tggtataatt tggtaagaaa acactttgac tcatattcat ttccttcttt
    30901 cttcgttgaa acgggttaaa attttaaaga gtgatcgatc tgactgcggc tgtagatgga
    30961 gtagaggtga acctaagaca ggataagtga tgaataaggt ggcatgaaca ccttgaaatc
    31021 atcaataagt atcctaaaaa cgaacaagta caaaaacatt gaaaacgaca ataatgaatt
    31081 tttgttcctc ttagtatttc taccgattcc ctttgctttt ttgtaattat ctaaaaattc
    31141 taaaaattaa gattattata tgaaaacagg ttttatttgt caattcataa ttggtttttt
    31201 ttaaagcaaa agataatcta tatcatgatg aacaaacaga gttttttcct ccaattgatg
    31261 gctttcctga tctttcctat tttgaataaa gtgtttctgt ataatttttt tattttataa
    31321 gtaagataaa taatgaaaga atagagatac tgattggtag ctaaagattt ttgagcgaga
    31381 acatttcgtt ttttcaaaag gactgttaga ataagcaaga acaaggggga agacgtatga
    31441 taatcagtga atttgaccgt aataatccag tattgaaaga tcagctttct gatttactga
    31501 gactgacttg gccggaagaa tatggagaca gctcggcaga agaagtagaa gaaatgatga
    31561 atccagaacg aatcgcggta gcagcggtag accaagatga gttagtagga tttattggtg
    31621 caatccctca atacggtatc acaggttggg aattgcatcc attagttgta gaaagctccc
    31681 gacgaaagaa ccaaataggt actcgattag tcaattactt agaaaaagaa gtagcttcca
    31741 gaggaggaat cacgatttat ttaggtacgg atgatttaga ccatggaaca acgttaagtc
    31801 aaacggacct gtatgagcat acatttgata aagtggcttc catccagaac cttcgtgaac
    31861 atccgtatga attctatgaa aaattaggtt ataaaatcgt aggtgtctta ccaaatgcaa
    31921 atggctggga caaaccggat atttggatgg caaaaacgat tattcctcga ccaaattctc
    31981 aataataaaa agaggttgtg acagaagtaa tcagcttcaa gaaataagaa ggaatttacg
    32041 aaaattactt cttgaatttt tgtgaaattc caacttattt ccgaagaagc tacttttgga
    32101 acaccgtgta ccagaggttg tgaaaaagtc gcttagtttc gagtagtaag aaaaattttg
    32161 tgaaaatggc tttctacatt tttgcataaa tttggcttaa taccgagaaa ctggcttttg
    32221 aacaccgttt attcagataa gggactgtga caagactttt gtcacagttt ctttttgttt
    32281 attctttttt atctttgtat ggcaataata gacaatataa cgaaaattat ttaatggctt
    32341 ttggaagacc atggaaaacc ttgtacaaag ctattttttc tgaaaaattc cttgaaacct
    32401 cacgaaaaaa tcattatttt atgaaaaaga caaaaaaaag tgttgatttt ttaataatta
    32461 ttcattaaac tcttaaacaa cttcagaaaa tattaattat tctgaaaatt ccaataaagg
    32521 ggtacgtaaa atgaaaaaga aatttacatt tggtttggtt gcggtatgcg gccttgtact
    32581 tgctggatgt tatggcggca gttcagccac aagcagtagt tcagcaaaaa gcggttcagc
    32641 agatggagga ggcgtattta acttagtcgt gcctcaagaa atgcctacag ctgacttatc
    32701 agttgcaaca gatacaatca gttttacagc attgaataac gtttatgaag gaatttaccg
    32761 tcttgatgaa gacagcaaac cacagccggc aggagctagc gagttggcag aagtcagtga
    32821 agacggatta acttacaaaa tcaaattacg agaagacgca aaatggtcaa atggtgatcc
    32881 tgttacagca gcggattacg tttatggctg gcaacgaaca gtagacccag ctacagcttc
    32941 tgaatatgct tacctgtatg cgccagttga aaatgcagaa gacattacag ctggaaagaa
    33001 agataaatca gaactaggga tcaaagcagt tggtgactat gaattagaaa tcaaattgac
    33061 gaaacaaaca ccatatttcc aatatctgct tgctttccca tcatttttcc cacaaaaaca
    33121 atccgtagtg gaagaaaatg gggatgccta tgcatctgca agtgataaag ctgtttataa
    33181 tggaccattc acattagaag attttgatgg accaggaaca gatacagaat ggacttataa
    33241 gaaaaatgat cattactggg acaaagatac agtaaaactt tctgaaatca aagtcagtgt
    33301 agtaaaagaa tcttctactg cattgaactt attcaaagat ggccaagcag atgacgtgat
    33361 cttgtctggt gagttagcac agcaaaacgc aaacgatcca gcttatactt ctgttaaaga
    33421 agcgcggaca agctatatcg aattcaatca acgtgaaaag aattcaccat tcaacaatgt
    33481 gaacctaaga aaagctattt cttattctat cgatcgtgaa gctttagtaa aacaagtact
    33541 aggtgacgga tcagttgtct ctacaggatt gatcccatca gatatggtaa aaagtccaac
    33601 aacgaacgaa gactttgcaa aagaagctgg aaaattagtt tcttatgaca aagataaagc
    33661 aaaagaatat tgggaaaaag cgaaaaaaga attgggcgtt gattctttag aatttgattt
    33721 gatggcttct gatgatgatt catcgaaaaa agtaatcgaa tatgttcaaa actcaatcca
    33781 agaaaacttg gatggcgtaa cagtcaaacc aacacctgtt ccattctctg tacgtcttga
    33841 ccgctcaact tcgggtgatt ttgacgcagt actaggcgga tgggctgctg actatgcaga
    33901 cccaagcagc tttactgatt tgtttgtcac aggtaattca tacaaccgtg gtcgctggag
    33961 caatgcagaa tatgacgaag cagttaaagc agcttcatca acagacgctg gcgatgaaca
    34021 agcccgttgg gatgatttcc aaaaagcaat caagatcatc tctgatgata tgggtgtcgt
    34081 tccggtgtac caaaaagcag aaggtcacct agtgaatgaa aaaatcaaag gtatcgttca
    34141 ccatgcggca ggcgcttcat gggattacaa atggacatac gttgaagaat aatcgttaat
    34201 accgtgagca tgagaaaaaa cgaggctgcg gcaaatgtcg caacctcgtt ctcatattca
    34261 cttatcctaa caaagaaaaa agcatgaaaa tagcagaaag agcaattagt attccggcaa
    34321 tgatcagcca aaagctgtac ataccgtagc tggcagacga gagcgaggaa aattctggtt
    34381 ttttctttcg gttccttgtt cgtgcaagat ggaccgatcg ctgaaaatga tcgaagaaac
    34441 ccgaagaaaa gacccataaa aaaccgccga taatcagaaa cggcaatgac cataagaata
    34501 gatcattaga taattgaatg agtgtaaagg aatggttgat gagatttttt attaaaataa
    34561 ccagaatcag tagaaaagct actgcgtagg ggatagattt ttttttcatt tgattgctcc
    34621 tttatttttg gttcattatc taataatgta gcgaaacatc tgtcagaagt caaaagctag
    34681 ggggaaacat tagtgaatag ttatatcaaa tatgtattaa aacgtgtctt tttcatgatc
    34741 atcacgcttt ggttaattgc aacaatcacc tttttcttga tgcaattgct gccgggcacg
    34801 ccatatacga atcaggaacg tttgagtcct gaaacaatcg agatgctaaa taaacaagtc
    34861 ggtttggata aaccagttat cgtacaatat gggatttatc tttctaattt gcttcaagga
    34921 gattttggaa tttccttcca atttaaaaac cagccagtcg cacatttgtt agctggaaga
    34981 atcggaccat ccttgcagtt agggttacag gcaattatct ttggaacagt cctagggacg
    35041 attttaggaa cgatctctgc catgaagcaa aatacatggg cagatacatc ttctacactc
    35101 gtagcgatat taggtcgttc cattccaaac tttgtatttg ctgttttatt acaatatatc
    35161 tttgcaatca aattacaagt tttgccaatc gcaaaatggg atggctttgt gtacacaatc
    35221 ttaccaacaa ttgcgttggc catgtcgccg cttgctgact ctgctcggtt tatccgtacg
    35281 gaaatggtgg aagtactgca tagtgattat gtggaattag caaaagcaaa aggattgagc
    35341 cgttgggaaa tcgcctttaa acatggtctt cgaaatagtt tgattccatt gatgacttta
    35401 ttaggaccgt tagctgtagc attgatgacc ggatcactgg tggtagaaaa tatctttgct
    35461 attcctggta tcggggaaca attcgttaag tcaatcacaa caaatgatta tcctacgatc
    35521 atggctgtaa cgatccttta ctcatttatg ctgatttttg ttattttgat cgtggatcta
    35581 ttgtacggtc tagttgatcc aagaattcgt gtttcagaag ggagccgagg ataaatggaa
    35641 atgataccaa agcgttatga aacagttgca gatatccctg cggatgaatt tcttccatta
    35701 caaaaaaata ccgaagaaga acgtgaacag attactgcac cttctttgaa ttttatccaa
    35761 gattcatggc gccgtttaaa gaaaaacaaa gctgccgtta tttcaatggt tttactattg
    35821 gtcatcattt tgatctctgt gatcacaatc tttgtttctc ctcatgatcc aactgcccaa
    35881 aacgtggctt atatcaattt gcctcctcgt attccgggaa tcaatatcga tggattgaat
    35941 ggaaaagcaa tggttggtgg tgaacttgtt gataaatatg ctcaagcaaa cgtcccttca
    36001 aacgtaaatt tctttttagg aacagacggt ttgggacgtg atgtattaag ccgcttattt
    36061 atgggaatga gaatctcgtt gctgatcgca tttattgctg cattactaga tgtaacgatt
    36121 ggtgtagctt acgggttggt ttctggtttg ttaggcggac gtgtcgataa cgtgatgcaa
    36181 cgttttttgg aaatcttatc aggaattcca aacctcgttg tcatgatttt gatgttggtc
    36241 gtttttgaac caggaatttt ttcaatcgtg gctgctatgg ccatcacaaa ctggatacca
    36301 atggcacgta tcgttcgtgc acaaacaatg aaattaaaag atcaagaata tgttttagct
    36361 ggattgacat taggtgaatc aagaatgaaa attgcattca aacatatttt gccgaatatc
    36421 tctagtgtca ttattattca aatgatgttt agtattccat ctgctatttt cttcgaagcc
    36481 tttttaagct ttatcggttt aggtcttacg cctccgtcag cttcattagg aacgatgttg
    36541 agcgaagggt acaagacatt cctgtatctg ccttatctat tatggattcc ggcagtaact
    36601 ttatcggtta tcatgattgg ctttaactta cttgctgatg gattgcgtga tgcctttgat
    36661 cctaaaatga aagagtgaag acgatgacga aaattttaga agtgaaagac ttagaaatct
    36721 cttttgatac gtatgctgga aaggtacgag cgattcgcgg tgtcaatttt catttgaata
    36781 aaggagaaac attggcgatc gttggggaat ctggaagtgg aaaatcagtg acgaccagaa
    36841 gcatcatgcg cttgctgtca agcaacgcca atatagatgc tggtcaaatc ctctttaaag
    36901 gtaacgatat cgttggaaaa tcagaaagag agatgcaaaa aatccgtggt aaagaaatag
    36961 cgatgatttt ccaagatcca atgacctctt tagatccgac gatgcccatt gggaagcaag
    37021 tcgctgagtc ccttagaaag cataataaag tttcaaaaaa agagggacaa aaagctgcat
    37081 tagaattgct taaattagtt ggaatacccg aagctgagaa acgtatcaac agttatccgc
    37141 atcagttctc aggaggtcag cgtcaacgga tcgtgatcgc gattgcactg gtatgttatc
    37201 cggaaatcct gattgctgat gaacctacaa cagcgcttga tgtgactatt caagcacaga
    37261 ttttggagct gctgaaagaa attcagacaa aaatcgatac atcaattatc tttatcactc
    37321 atgaccttgg tgtagtagcg aatgtcgctg atcgtgtcgc tgtcatgtat ggaggaagaa
    37381 tcgttgaagt tggaacatcg gaagaaattt tctacaaccc gcaacatccc tatacttggg
    37441 gactgcttgg ttcaatgccg acattagata gtgcgaacga tcgattgtat gctattcctg
    37501 gttctccacc ggatttattg aacccgccaa aaggagacgc attctatcca agaaatgaat
    37561 tcgcgatgaa aatcgatgca gaacaagaac caccattttt tgaactatca aaaacacaca
    37621 aggcagcaac ttggctactt gctccgcagg cacccaaagt gacaccgcca gaagaaatcc
    37681 aacgtcgctg ggctatcttt aaagagaaac aaaaacatac ttacggtcaa ggaggaattg
    37741 ctgatgccaa ataaactact tgaagttaaa ggattgaaac agtatttcaa tgtaggaaaa
    37801 aagaatgaag tacatgctgt aaatgacatc agctttcaca tttatgaagg agaaacattc
    37861 ggtttagttg gagaatctgg aagcggaaaa tccactactg gccgtacgat cattcgcttg
    37921 aatgaaccta ctgatggtga gatattattc gacggtcaag atataacgaa gatcaaagat
    37981 aaaaaaggtt tgacgaaatt ccggcatgat gttcagatga tctttcaaga tccatacgct
    38041 tcgttgaatc ctcgtatgaa agtcagagat atcattgccg aaggaattga tgttaatgga
    38101 ctagctaaat catctgaaga gcgtgcaaaa aaagtcgatg atctattgag aactgttgga
    38161 ttgaatccaa gccacggtac tcgttatcct catgaatttt caggtgggca acgccagcgt
    38221 attggtattg cacgagcatt ggcagtaaaa ccgcgtttta tcatttgtga tgaaccaatt
    38281 tctgcactag atgtgtcgat ccaagcccaa gtggtcaatt tgttgcaaga tctccaaaaa
    38341 gaacatcaat tgacctatct atttattgca catgatttgt cgatggttaa acatattagt
    38401 gaccgaatcg gtgtaatgca taacggcttg ttattagaga tgggaacaag tgatgaaatc
    38461 tataatcacg gtgttcatcc ttatacagaa agtttgttat ctgctattcc tctaccagat
    38521 ccagaccatg agagaaaacg cagaagaatc aaatatcaac ctgaaccaga tgacggacaa
    38581 gtacgtcaac ttcgtgaaat cgcaccagaa cattttgtct atgcaactga gcaggaagtc
    38641 ccatattacg caaaaaaact aaaacgacaa aaggaatctc ttctggttgc taactaggag
    38701 ggacatagat gctaaaagct tttaaattcc gtatgtatcc gacagaagaa caaaaacagc
    38761 aattgattcg tacttttgga tgtgctcgat ttacctataa ccatttgctg aaaaagcggc
    38821 agaaaagttg gcaacaaaca ggagtagcca atttttcgct cacacccgct acattaaaaa
    38881 aagaataccc attcttaaaa gaagtagaca gtcttgcttt agcaaatgca cagcttaatt
    38941 tggatcgggc ttttcgcaat tatttcaagg gacgtgccag cttcccaaag cttaaaacga
    39001 aaaaaagtat gtggcaatct tatacgacca acaaccaaac ccgtacgatc tatctggaaa
    39061 atggctactt aaagttacca aaacaaaaag aactaatcaa gataaatcag catcggccag
    39121 ttgaaggatc gattcgctcc gctacgattt ctgctcgata taatgaagaa ttttatgtcg
    39181 cactactttg tgatgtttcg ccagtaaaaa aagaatcttt agctaaatgg atcgggatcg
    39241 cctatcatcc gaagacattg atccaaacat ctcgacctct agaagtaact ttaccaaaat
    39301 ttcaccagac agaagaaaag ctgcaacatg cacagcggaa attgaatgtg aaagtccgct
    39361 ccgctcacca tagaaagatc aggttagatc aggcaagcaa ttatcagaaa caaaagagaa
    39421 aagtaatgga tctttatctg aaacaaaaga accagcgaga agattatctt gaacaattat
    39481 ctgggaaatt ggtcaaacaa tatgactact tatttgtaga atcttttcca aaagaagagg
    39541 cacatgctga tttttctatt cacgactggc ataaattaat aacaaaattg cgttataagt
    39601 cccaatggta taataaaaaa tttcttttga tcaataccga cggagcagaa gaaagcaatt
    39661 ccgtaagaaa gagccaagta gtagaaaaaa tgggcagaca ttcggttatc aagggataaa
    39721 aaatgaatga aactgatagg agcgttaggg ttagccttgt taataaaaag tcttaatgac
    39781 ttttgtttct aggaattttt cttttgaaga aaagctcact aattatgaca aaccaataaa
    39841 acaatagcag aaaaagttcg tacgagcttt ttctgctatt gttaattttt
//
LOCUS       DAFEKH010000024        39074 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.025, whole genome shotgun sequence.
ACCESSION   DAFEKH010000024
VERSION     DAFEKH010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39074
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.025"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            6..305
                     /locus_tag="LP386_001383"
     CDS             6..305
                     /locus_tag="LP386_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1918624.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="LP386_001384"
     CDS             378..1739
                     /locus_tag="LP386_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBL1918625.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="LP386_001385"
     CDS             1761..2021
                     /locus_tag="LP386_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918626.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="LP386_001386"
     CDS             2035..2787
                     /locus_tag="LP386_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBL1918627.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="LP386_001387"
     CDS             complement(2881..3486)
                     /locus_tag="LP386_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL1918628.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="LP386_001388"
     CDS             complement(3539..4513)
                     /locus_tag="LP386_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HBL1918629.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5610)
                     /locus_tag="LP386_001389"
     CDS             complement(4891..5610)
                     /locus_tag="LP386_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL1918630.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="LP386_001390"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="LP386_001390"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBL1918631.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="LP386_001391"
     CDS             7161..8558
                     /locus_tag="LP386_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL1918632.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="LP386_001392"
     CDS             8639..9079
                     /locus_tag="LP386_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBL1918633.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="LP386_001393"
     CDS             9227..9553
                     /locus_tag="LP386_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBL1918634.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="LP386_001394"
     CDS             9554..10303
                     /locus_tag="LP386_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918635.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="LP386_001395"
     CDS             complement(10383..10838)
                     /locus_tag="LP386_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBL1918636.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="LP386_001396"
     CDS             complement(11265..11540)
                     /locus_tag="LP386_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918637.1"
                     /translation="MKLEDKKVILKKIKRLPEQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="LP386_001397"
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="LP386_001397"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HBL1918638.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(12978..14429)
                     /gene="cls"
                     /locus_tag="LP386_001398"
     CDS             complement(12978..14429)
                     /gene="cls"
                     /locus_tag="LP386_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBL1918639.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            14770..17436
                     /locus_tag="LP386_001399"
     CDS             14770..17436
                     /locus_tag="LP386_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBL1918640.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            17800..18552
                     /locus_tag="LP386_001400"
     CDS             17800..18552
                     /locus_tag="LP386_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL1918641.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(18574..19728)
                     /locus_tag="LP386_001401"
     CDS             complement(18574..19728)
                     /locus_tag="LP386_001401"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HBL1918642.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            19913..22354
                     /locus_tag="LP386_001402"
     CDS             19913..22354
                     /locus_tag="LP386_001402"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HBL1918643.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(22684..23388)
                     /locus_tag="LP386_001403"
     CDS             complement(22684..23388)
                     /locus_tag="LP386_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918644.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(23575..23820)
                     /locus_tag="LP386_001404"
     CDS             complement(23575..23820)
                     /locus_tag="LP386_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918645.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(23837..24688)
                     /locus_tag="LP386_001405"
     CDS             complement(23837..24688)
                     /locus_tag="LP386_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBL1918646.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            24854..25858
                     /locus_tag="LP386_001406"
     CDS             24854..25858
                     /locus_tag="LP386_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBL1918647.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            complement(26099..26455)
                     /locus_tag="LP386_001407"
     CDS             complement(26099..26455)
                     /locus_tag="LP386_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBL1918648.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            26823..28010
                     /gene="tuf"
                     /locus_tag="LP386_001408"
     CDS             26823..28010
                     /gene="tuf"
                     /locus_tag="LP386_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBL1918649.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            complement(28198..30789)
                     /gene="mprF"
                     /locus_tag="LP386_001409"
     CDS             complement(28198..30789)
                     /gene="mprF"
                     /locus_tag="LP386_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBL1918650.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(30815..31576)
                     /locus_tag="LP386_001410"
     CDS             complement(30815..31576)
                     /locus_tag="LP386_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL1918651.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            31854..32375
                     /locus_tag="LP386_001411"
     CDS             31854..32375
                     /locus_tag="LP386_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HBL1918652.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            32434..33294
                     /locus_tag="LP386_001412"
     CDS             32434..33294
                     /locus_tag="LP386_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HBL1918653.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            33479..35794
                     /locus_tag="LP386_001413"
     CDS             33479..35794
                     /locus_tag="LP386_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBL1918654.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            35976..37817
                     /locus_tag="LP386_001414"
     CDS             35976..37817
                     /locus_tag="LP386_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBL1918655.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            37841..38950
                     /gene="rpoD"
                     /locus_tag="LP386_001415"
     CDS             37841..38950
                     /gene="rpoD"
                     /locus_tag="LP386_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HBL1918656.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
BASE COUNT        12571 a         6876 c         8095 g        11532 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaaa
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttgctct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaagaact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattcg ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag ttgccctgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg
    12721 tttttaactt ggttggactt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    12781 aggtcgtgag cctgccgtcc agctccgagt cacaaggaac aagttcaaaa aacagcttct
    12841 catgtttgtt gaatattgtg acttgtgacc gaggagttgg caggagaaca ccgtttgttc
    12901 ggaagaaggg actgtgacaa gatttttgtc acagtccctt taatcttagt atatttttct
    12961 ctacttgaat aaaaaaatta taggattgga gaaaataatc gagaaatttg ttgcttgaat
    13021 aatagccagt tagacatttc cttgactgtt tcagttgtca tggatgaaca atgtgtctca
    13081 tcttctttga actgagtagc aagttcttct aaaaactcag gatcgtaaat gacagcactt
    13141 gtttcaaaat tcaatcggta gctacgaata tcttgatttg ctgaacctac catgcagatt
    13201 tcatcatcca ttatcaatgt ttttgcatgg aggaagccgt tctcatagac aaggatttgt
    13261 acattttcct tgatcagctg ccgagcataa tattgtgttg ctcgataaat aaaaggatga
    13321 tccggtttgt tgggaatcat gattttcaca tctacaccag aggcagttgc gatttttaaa
    13381 gcagcaatga cactttcatc aggaacaagg taaggtgtct gtatccaaac acgtttttta
    13441 gcagaagtaa tcaatttgat aaatgaaagc ttgatttgtt ccctttcgtt attcggtccg
    13501 cttgaaacaa gctggatgga tgtatcagca agcttagatt catctcgatc tgctttttta
    13561 aagaaataat tcaaatgata gccgaccttt ttttcttcag gtaccgagac gttccagtct
    13621 gttaagaagc gaagctggag caaagaagaa gcggcaccga aaatccgtat atgcgtatcg
    13681 cgccaatagc cgaatttttt tgttgtattt acatattgat tggcaatatt gaaaccaccg
    13741 gtataactaa tctttccatc gatcacaacg atttttcggt gatcatggta attcaatcgg
    13801 aaacgaagta atgccctttg tgaggtaaca aatgtatgga catgtccacc atttttgatt
    13861 agacgattga aatcttttgc ttttgtgcca tgagagccaa atgcatcata taatattcga
    13921 acttccacgc cttctgcggc tttttcttct aaaacatgta agacttgctg gccgatatta
    13981 tctgtcacaa atgcgtaata ttcgatatgg atcgaatgtt tggctttttt tagatcttga
    14041 agcagtgaat ccaatttctc ttgtccgtct gtgagaagag tgacagaatt cattcttgtc
    14101 agcggcatac gatttaatga agagaagaag tcaacaaatt gctgtttgtc tttatcgccc
    14161 atgtcaggat cgtaatgttc aatggtatct cctctaaaag actgaaagtt ttctaattct
    14221 ttcaagtcac tttgtcggag atagaatttt ttcttatccg ttaatccacg tccgaaaaat
    14281 aaatataata caaagcccac cccaggaagg gcaaacaata ctaagagcca tgcccaaatg
    14341 gctgctacat ctcggggttt gatcaaaata gccaccaaag caataagtgc atttaataga
    14401 taaagggcgg ttataatact agataccaca aaaatgttcc tccttacata caataacatt
    14461 agtatagcat gatagaagaa agaagcctac caaggtgaat atacttttca ctcctttcat
    14521 gaaaatgtag gtaaatcggg ctaaagtagt tgctttttgt aggttaataa ggtaggatat
    14581 tagtacagtt gaatatctcc ttaggggagt aaccggcaac gtttgttgcg ataatatcaa
    14641 cagtaagtta accaaatggt tttctggtat tgtatgaaat ggtgagacct aagacaaatg
    14701 cgtatttgtc ttaggtctct tttttttcag acaggactag ggccaagatc aaaaaatggg
    14761 ggatgaaatt tggaaaacaa ggaacaagca caacaagcgg tctataaaga aacgatcgac
    14821 tcgttgatgc agcaaacgca gagctcaacc gatggattga gcaccacgca agcgaaggaa
    14881 aaattagaaa gagatggctt gaaccagcta aaagaaaagc cgaagaagcc aacttggaaa
    14941 ttgttcttag aaactttcaa agatgcaatg gttatcgtat tgctgattgt cgcactgatt
    15001 cagatggtca tgggtgacta catcgaattc ttagttattt ttgcagtatt gatgttgaat
    15061 tctataatca gtgttgtcca aacaaaaaaa gcagaaggtt ctttagaagc gttgaaaaac
    15121 ctttcagcgc ccgatgctcg agtgattcgt gatggtaagg aaaaaacgat tccggcaaac
    15181 gaacttgtgg taggagatat cgtgttgtta gacgcaggcg attatgtacc tgctgatgga
    15241 cgtttactag atgcgggatc attaaaagta gatgaaggta tgctgacagg agagtcgact
    15301 tctgcagaaa aagaagtaac ggatatcaca agtacggtac caatcggaga tcgtacaaat
    15361 atggtattca gtggaacgat cgtaacttac ggacgcggta aattcttagt gacttcaact
    15421 gggaataata cggagatcgg acaagttgct ggccttttgg aatcaacaac tgagcaagtc
    15481 actccgttac aacgaggtct ggataaattc agtaaaaaac taagtttggc tattttggca
    15541 ttgtctttat tgattttagg tatccaactg tttcgtattt atcttggaga aggtacagga
    15601 gatatgactg cagatatcgt cagcgcagtg atgtttgccg tagccgtagc cgtagctgct
    15661 attccagaag cattacagtc tatcgtaaca atcgtgttat ctttgggaac gaataaaatg
    15721 gcaaaacgtc atgccattat tcggaagctt ccagcagttg aaacacttgg ttcgacaagt
    15781 atcatctgta cagataagac tggtacattg acacaaaaca aaatgacagt tgttgactac
    15841 tttttaggta atggcgatac tggggatttc acaaatgacc cttcaaaatg gacagctgac
    15901 gaacgtcgct tgatcgaaat cagtgtttta gcgaatgatg catcgatcag tgaagacggt
    15961 actaaattgg gcgaccctac ggaagtagcg tttatcgact ttagtgaaaa attaaaccag
    16021 ccttatcagg aaatccgaaa caactaccca agacaagcag aacttccttt tgactcagat
    16081 cgaaaattaa tgtctactgg acacacaatt gataacaaaa attacttgtt tgttaaaggc
    16141 ggaccagata tcgtcttcca acgcagtaaa aaagtattgc taaatggtga agtcgttccg
    16201 atgacggatg aattgatgaa aaaattccaa gagcaaaatg aagctttttc aacacgcgca
    16261 ttacgtgtac tagcttttgc ttaccgtcca cttgataatt ttgatttatc atttgaagat
    16321 gaagacgatt tgatccttgt tggtttgctt gctatgatcg atcctccacg tgctgaagtg
    16381 actcaggcgg taacagaagc aagaagtgca ggaatcaaaa caatcatgat tactggtgac
    16441 cacaaaacaa cagctgttgc tatcgcaaaa caaatcggga tttttgaaga aggaaacctg
    16501 gctttgaccg ggacggaact agatgaattg acagaagatc aactaaacga agttttagaa
    16561 aaagtcactg tttatgcacg tgtttcacct gagaataaaa ttcgtatcgt tcgtgcttgg
    16621 caaaataaag gtcatatctc agctatgaca ggtgatggtg taaatgacgc accagcattg
    16681 aaacaagcag acatcggaat tgctatggga acgggtacag atgtggcaaa agatgcagca
    16741 gcgatggtat tgacggatga taactttgct tctattgtca gcgcagtaga agtaggacgt
    16801 aatgtgtttg ataatatcaa gaaagctatt tcttatctat ttgcaggaaa tttaggtgcg
    16861 atcattgcga tcatctttgc cttagttgct gactggtcca atccatttac agcattacaa
    16921 ctgttgttca tcaatttagt caatgattca ctgccagcaa ttgcattagg tacagaaaaa
    16981 gctgaacctg ctacgatgaa ccgcccgcca agagatccaa attcaggaat ctttacggac
    17041 aaaacattga tttctgtaac gtatcgtggt gtgctgattg ggattgctgt tatctttgct
    17101 caatggcttg gcatgcagca ttcacctgaa ttcggtgtag ccatgtcatt ttcaacattg
    17161 atttggtgtc ggacattgca aacattccca gcacgttcaa acacacaaac agctatccaa
    17221 gcagggttct tctctaacag aagtgtctta ctagctgtag ttgtatgtag cgcgctttac
    17281 tgcttaacaa tgatcccagg actgaaagaa gtcttctcta tcccatcagc atttggattg
    17341 acagaagtct ttacatgtat gggaatcgca cttgtgacaa ttgttttgat ggaaatcact
    17401 aaattgatca ttgtacgagt acaaggaaat aaataaaacg aatcaacgag gttgtgagcc
    17461 tgccgtttaa ttctgagtca caaggtgcaa tttcaacaaa cagcttctca tgtttgttga
    17521 atattgtgac ttgtgaccga agagttggca ggagaacacc gtttaaggaa gaagttgtaa
    17581 aatcagcatt ttgagctaat actgagggtc atctgattgg acactgttta ttcggaaaga
    17641 gggactttga cacgactttg gtcacagtcc ctttttttat ttatgataga cggaaagcca
    17701 atcattttat tattcatcaa aagagataga atagataaaa gaggagaatg atttattccg
    17761 aaaagtgaaa acatataaca aaaaattaga ggaaatcaaa tgaatgaaaa agaatgggat
    17821 gaatttgctg aagaatatta tgaaatccag caagaatcgc aagtaactat tgctgaagat
    17881 gtaaaaaatt atctgaaaac ggagaaagtc ctgcctgctg aaacagcagc agacgttgct
    17941 ggaggatctg gcagatttct ttccttagca aaagaaatta atcgctatga tttgatcgat
    18001 ttttcttcag gaatgctaga aaatgcaaaa aaagaagcag aaaaaaatga gttgccaaat
    18061 gtttccttta tcaaacagtc gttagaagaa tttatccaat caaatgagac atatgaaatg
    18121 gtttttacag cagcaaatcc agcattggta catcttattc aattagaaaa attgatgaaa
    18181 aagtcaagca aatggtgcgt gataatcaga gtagtggaat caatcgatga tgttttttat
    18241 cctatcgaaa agcaactagg aatgatagaa gaagatccta atacatcgcc agttgtaatg
    18301 gatcaatttg aaacatactt aattgatgaa ggattcaaag tgaagaaaaa agattttact
    18361 tattttacac aggaatcaat tactgaagaa ttgatgaagc tatactatga cgcgtacgca
    18421 aaagatcctg ttgtgaccag gtacattcgc aaactattca gtgaaaaacg agaaatcctt
    18481 agtacgacta agctgaccta tagactgctc ctttggtccg cagataaaaa aagaaccttt
    18541 cacgactcgt gaagggttct ttttatgatt ttattatatt ttgtagtaac gaatatcatt
    18601 ttcgatcttt gtaatcgaaa aaggtacatc tgaagtatat tctgcacatt ctccgtgttc
    18661 aggaagcgtc tcactgaaaa tcgtttcata ttcgtcaaca gtgatccgtg ttcgagaatc
    18721 tagcatctct tgatgagatt gtgcgaagag atattcttga tagttttctt ccagataacc
    18781 tgtaaaaaat tcacttactg caccagaacc gtagctgaat agaccgatgc gatctcctgg
    18841 ctgtagtgat ttcgaatttt ccagtagaga agttagcccc aggtataatg aaccagtgta
    18901 aagattaccg attcgtcggc tgtaacggat gctttcttca tagcgagcca taagacgttc
    18961 ctgattttct tcgtctgttt ggtctaatac gctttgcaat gccttttttc ccatcttagt
    19021 atacggaata tggaaagcaa tcgcctgata atcttcgagt cctcgacccg acaattcttt
    19081 atgtcgattc caaacttttt ggaatgattc gatatacgta gaattagata aaggaccatc
    19141 aacaacagga aattcgctat aatctggacg ccagaaatca tagatatctt ctgtcagaaa
    19201 tacgctgtcg tcttcaatcg ataaaatacg cgggttttga gtgatcatca tcgcaacagc
    19261 accgacacct tgcgtcactt caccaccgct tgccaagccg taacgagcaa tatcacttgc
    19321 tatgactagt acttttcgtt ctggatgatt tttgacatat tctttcgcca tgtgcaaagc
    19381 tgcggtgcca ccgtagcaag cctcttttac ttcaaaagaa cgagcaaaag attggatttt
    19441 cagtaaatgg tggataatta ccgcactcgc ttttgaatga tcaatcccgg attctgttcc
    19501 gacgatgacc atgtcgatta gctcacggtc tttttctgtt acgattttgc tggcagcatt
    19561 tgctcctagt gtaatgatgt cttcatttgc acgattgact gccatttggt cttgaccaat
    19621 ccctatatgg tattttgcag gatcatcccc acggctttct gccaactctg tcatatctaa
    19681 atataaatta ggaataaaaa aggaaagacg atcaatccct attttcattt caacacctct
    19741 ttacttatga taaaaaactt actttactaa ggtatcataa aaagattaaa agaaatataa
    19801 aaaagagaat atttaaggat tgttaaaatt taatcttaga aaaaaataac tggaacaaga
    19861 gctatttgtt tttacagcaa agaatggtat atttttgtag gaggtggctt acttgaaaga
    19921 agtcgttatg atagatgctg caagaacgcc gataggaaag tatcgcggaa gtttaagtcc
    19981 atttactgca gttgaattag gcacacttgt gactaaagga ttattagata aaacaaaact
    20041 gaaaaaagat aaaatcgatc aagtaatatt tggaaatgtc ctgcaagctg gtaatggtca
    20101 aaatgttgcc agacagattg ctttgaacag cggtctccct gtagatgtcc cagcaatgac
    20161 gatcaatgaa gtttgcggat ctggtatgaa agcagtgatc ttagcacgcc agctgatcca
    20221 attaggtgaa gcagaacttg tgatagccgg cggaacagag agtatgtctc aagcacctat
    20281 gctgaaacag tatcagtcag aaacaaatga atatggtgaa ccaatttcca gtatggtcaa
    20341 cgacggattg actgacgcat tttcaaatgc acatatggga ttaaccgcag agaatgttgc
    20401 aacacaattt tctgtgagca gagaagagca ggatcgctat gccttgtcgt cccagttgaa
    20461 agcagcacat gctgtcgaag ccggtgtatt ttctgaggag atcatcccag tcaagatttc
    20521 tgatgaagac gtgttatctg aggatgaagc agttcgtgga aatagtacat tggaaaaact
    20581 gggcacgtta cgtacagtat tctcagaaga aggaactgta acagcaggaa atgcttcccc
    20641 gttgaatgac ggtgcctctg tggtgatcct tgcatccaaa gaatacgcag aaaataataa
    20701 tctgccttat ttagcaacca tcaaagaagt agcggaggtc ggtattgacc caagtatcat
    20761 gggaatcgct ccaatcaaag ccattcaaaa attgacagat agatcaggaa tgaatttatc
    20821 aacaatcgat ctttttgaga tcaatgaagc atttgcagct tcttctatcg tagttagcca
    20881 agaactgcag ttagatgaag aaaaggtcaa tatatatgga ggagcaatcg cattaggcca
    20941 tccaattggt gcaagcggtg cacgtatctt gactacatta gcttacggat tgcttcgtga
    21001 acagaagaga tacggtattg cttcattatg tattggtgga ggtttaggct tggcagtctt
    21061 gttagaagcg aatatggagc aaacacataa ggatgtgcaa aaaaaaaagt tttatcagct
    21121 tacgccatct gaacggcgca gtcaattaat agaaaaaaat gtattgacac aagaaactgc
    21181 gttgattttt caggaacaaa cactttctga agagctctcc gatcacatga tcgaaaacca
    21241 agtgagtgaa gtggaaatcc caatggggat cgcgcagaat tttcaaatca atggcaagaa
    21301 aaaatggatt ccgatggcaa cagaggaacc atctgtcatt gcagctgcaa gtaatggtgc
    21361 aaaaatctgt ggaaatatct gcgcagaaac acctcagcgg ctgatgcgag ggcaaatcgt
    21421 tctatcagga aaatcggagt atcaagcagt gatcaatgca gttaatcatc gaaaagaaga
    21481 gctgattctt tgtgcaaatg aaagttatcc ttcaatcgtg aaacgcgggg gcggtgttca
    21541 agatatctct actcgggaat tcatggggag tttccatgca tacttatcta ttgatttttt
    21601 agtggatgta aaagatgcaa tgggcgctaa catgatcaac tcgattcttg agagtgtggc
    21661 aaacaagtta cgggagtggt tccctgaaga agagattcta ttcagtattt taagtaattt
    21721 tgctacagaa tcattggctt ctgcctgttg tgaaatccca ttcgaacgct tagggagaaa
    21781 caaagaaatc ggtgaacaaa ttgccaaaaa aatccaacag gcaggggaat atgcgaagct
    21841 tgacccttac cgtgcagcaa cgcacaacaa agggatcatg aatggtatag aagctgtagt
    21901 ggcagctaca ggaaatgata cacgtgcggt tagcgcttcg atccacgcct acgcggcaag
    21961 aaatggatta taccaaggat taacagactg gcagatcaaa ggggataaac tagttggaaa
    22021 actaacggtg cctttggctg ttgccacagt aggcggagct tccaatatcc tgccaaaagc
    22081 aaaagcatct ttagctatgt tagatattga ttcagccaag gaactagcac aagtaattgc
    22141 tgcagtaggg ttagctcaaa acctggctgc tttgcgtgca ttagttacag aaggaatcca
    22201 aaaaggccac atgggacttc aagctcgttc attagcgatc tcaattgggg ctattggtga
    22261 ggaaatcgag caagttgcga aaaaattacg tgaagcagaa aagatgaacc agcagacagc
    22321 tatacaaata ttggaaaaaa tccgggaaaa ataaaaaagc aatatcttta gaagaataaa
    22381 gcaagattta cagttatttt atttactgca gatcttgctt ttttctctat cagaaaatat
    22441 gtttattatt agaatttttt atagttaagg ttaggcatct taagaaatca ggcaactcca
    22501 agatatcttc aggtagaaga gaagtcgcct aacattgtag gatcataggt gatttgttgg
    22561 acaggtcaag ctgatatttg agcctgatgt tagaaggaat ttctttttac ttgctgtaga
    22621 aattattata tgactaaaaa ggctgggatt ttaaatccca gccttttatg acaaatagaa
    22681 tttttatcga tcagtaatcg ctgtcgctgc aaattgttcg atcaaaggaa tcaaagtcaa
    22741 tttgactttg tatttccgtt cgagtgcttt ttcgataacg aactcatttt cagtagtcat
    22801 agaaatagtt gctaatttac gaggttcatc agcatttttt tcattaataa ctacttcatg
    22861 ttcattttgt tctgtgtaaa atttaggata ctcagcaacg gcttttgaaa aatcagcaaa
    22921 acttaaagcg gcattcgtat cagttgagcg tgtattttca gttgtgtccg cttttggttt
    22981 ttccgttttt tcttctggca cactgactgt ttcttctgta actggtgtcg caacagcttg
    23041 cgcagttggt tcatcgtttt tcaatcgttg atcattccag taagacacga tttcaataag
    23101 aagattgtca cggaatcgtt cgaaaatccc gttttctcct gaacgaattc tctttaatac
    23161 agtattgaag ttgtcatcga ttggcacgtt gatccgtgta tcttcatttg ttttcccagc
    23221 taatccgatc gttaagattt gacggttttt gggatcaagc atgacttgta acggcaaacc
    23281 ataacgtcgc aagctctctt cttctagaga acggaataat tgtcctctta caccatccaa
    23341 tgaaggacgg aattgattta ataatttttg tttctgtttt ttcttcatat gttctctcct
    23401 tcgctcatac cctttcgatt ataagaaaaa aacagccaaa tgaaaaggag taatgcaaaa
    23461 aaacttgcgt atacgcaaat tacaacagaa aaatttgcgt attttcccgt tttttgaaag
    23521 aaaaataaaa aatggaacgg attatgtata tatacataat ccgttccatt ctttctattt
    23581 tttcggtatc aaggcaaaaa caggtagttc aggtgaataa atgacttcat gttcgtgcca
    23641 gggtttgacc attagcgaat gatcgaaccg ttttttcagt tcttcgatga tttgatcatg
    23701 tgtccagttt cttgcaggaa aatgttggat tttctctgca tcgatcaaaa agacaaaatc
    23761 ggaatgaaaa gtctgggtaa cttcttccga gagagaattc aagcgttcga ttggatccat
    23821 aaaatcacct ttcgacttaa aattgggtag tatctgggtc ttttgctttg ccgactacac
    23881 catctaactg atcgatttgt ttcatttctt cttctgttaa ttcaaaatca aataattcag
    23941 tattttcttt gattctgctt ggtgtcactg acttaggaag aggaaggaat tcgtgttgca
    24001 gcgaccaacg caaagcaact tgtgcaatcg tcttgtcatg tgcttcagcg atttgtttca
    24061 tttcaggcac atcgaagatt ttaccagtgc ctaatggact atatgcttcg aggatcatat
    24121 catgtttttt tgcatactca actacagttg tctgtaattc gcctggtgca aggaaaactt
    24181 gattgaccat cggcataatt tttgctgttt ttgctagtgt atctagatgg tggggtaaga
    24241 aattgctcac accgattgct ttgattttac ctgcttcata cagttcttca aatgctcgcc
    24301 atgtatctgc atttgcttgt tcccaattat cacgaaaagc aacagggttt ggccagtgga
    24361 tcaaaaacag atctaaataa tctgtttgga gcttcttcaa tgattcttca aaagaagaca
    24421 tcacaagttc atagctgtgg tttgcattcc ataattttgt tgtcaagaat atctcttctc
    24481 taggaattcc actttcctta atcgcttggc cgacgctttc ttcattcttg tatccttggg
    24541 cagtatcgat atggcgataa cctgcagcca gcgcttcttt aacagaggaa acagcgacat
    24601 ccccatcagg tgtttgccat gtgccgaatc ctactaccgg gatttcgtaa ccatttgata
    24661 gacgataagt gcttgttaat gaattcatac tttcagctcc ttttttattc gttcaactat
    24721 aagtgtagcg catttttcga aaaaaagaat ccattttgtt tctactcttg aaatttttgt
    24781 ttaaaagaaa atgattttga ttctggtatt tttgattttt tttccgtaaa ctaagacaga
    24841 agggaatgag aaaatggata tctatttaaa aaaagcaatt ctgcatatta ttgacagaga
    24901 aactggttct ccagtctttt cacaaaaaga gctggatctg acaaaagaat atattcgtga
    24961 ttttcttcaa aagaagatcc aaaaaatctc ttctgctcaa acaaaaactg gacaactagc
    25021 agaagaaagc atgatcgttg aatcacttaa aatcgctcaa gaaaattttg tggaagcaag
    25081 tgaagcaatc gttcagcggt ggttcgatat ctaccaagaa agtgaagaag cacctagtgc
    25141 agatgtattt gttgtcttgt atgaattaga tacagtgatg tacttatctt tattgaaagt
    25201 caattatcgt gaggcttaca ctcactttgt tgaagcagac gaagcaggga tcgacaaccg
    25261 cttgattttg aatcgagcaa ttctaggggc gaaaacacaa aaagcagatg aagcattcgc
    25321 tgtgaatttg actgattgga cctacgaatt aattgaaaaa aaatatgagt tttctggcaa
    25381 aaaagagctt tatttttctg gaagagtgat cgaaagtgtt cctgcacctt ctttagaaga
    25441 aaatgtaaaa gtgatccaaa aagtagccaa gcatcttgga aaaaaatttg agacagaaga
    25501 atttgatatc atggctgatt tgaaagaagc tgtctatgat acgatagaag aaaaaggtcg
    25561 gttggatcat gagatgattg cggaaaaagt cttcaaggaa aacatcacgg caaaaatggc
    25621 ttttaaagaa gaagtacaag agcaaggatt tgtcccagaa gcacctcctg taaaagaagt
    25681 acaagaaatt tctgagaaaa aatttggaaa acaaaaattc aagctatcaa acgggatcga
    25741 actgatcgta ccagtagatg tatatcgcaa cccagatttg attgaatttg tgaataatcc
    25801 ggatggtacg atatccgtga tgatcaaaaa tgtggatgaa gtattgaatc gtttataaaa
    25861 atgactagaa tattaggtgt tcaagtacca gtgatcagtt aaatgaattg tgtcaagaga
    25921 aggatcggaa aagacgaata taacaaaaaa agagcgtgag acaaaagtaa agaacacttt
    25981 tgtctcacgc tctaaacacg tataaacggc ggaagcagaa gcaactcctt cttatttctt
    26041 ggagttaaac gcttctgtcc cagcctcttt ttatctaata aaattttaag accatttact
    26101 aattatcgat tttttctgcc gcatttttag gcacttcaga agcctttatt tcttcccagc
    26161 ttaatacacc tttacgagga ttgactttga gtttaagata cgcattcatc tttaatggat
    26221 gttctctttc ttcgcgaagc gtcacctgtt ttttttcacc atctttatta taagccgctt
    26281 gcttgtaggt ataagtcgtg aatttctctc cgttatctgc ttgggtagct gacatttcgc
    26341 cattcgtcgt gatttttgta taataagctt cgccgccgta aaaataatga taagctgcaa
    26401 aacttccgcc gagaaatatg cctaaaacga caagtacgcc aattaatttt ttcatgtact
    26461 tcacctcttt ccttattatt aacgaaatag aagatttcgt ctattgaaag ttgttggcaa
    26521 cagctgaatt ttaaactttt cctcattttg ttcttattgc ttcaaaagaa agttaaggac
    26581 tatcttgaag tttttctcaa aaaacacatt tttttattta taaaaggtac ttttttcgcg
    26641 tataagacag acgagtgctc ttagttgact ttgaccaata ttgacgtata ataagcttag
    26701 ttcgaatctt acaaaaagta agtcggacgt attctttttg atttagtcaa aaaaagacta
    26761 taataaaaag gtgagagctg aaatttttca gtgatctata ttatttagga ggtttgtaaa
    26821 ttatggcaaa agaacattat gacagaagta aaccacacgt taacattggt acgattggac
    26881 acgttgacca tgggaaaact actttaactg ctgcgatcac tacagtatta ggcaaaaaag
    26941 gcctagcaaa tcctcaagac tatgctagta ttgatgcagc tccagaagaa cgtgaacgtg
    27001 ggattacgat caataccgca cacgtagaat atgaaacaga aaaacgccac tacgcgcata
    27061 ttgatgcacc aggacacgcg gactatgtga aaaacatgat tacaggggca gcacaaatgg
    27121 atggtgcaat cttagttgtt tctgcaactg acggtccgat gcctcaaaca cgtgaacaca
    27181 ttttattgtc acgccaagtt ggtgtaaaat acctgattgt tttcttgaac aaagttgatt
    27241 tagtcgatga tgaagaattg atcgatttgg tagaaatgga agttcgcgag ttattgagcg
    27301 aatatggttt cccaggcgat gacactcctg tgatcaaagg ttccgcatta aaagcattgc
    27361 aaggcgatcc agatgctgaa gctgctatta tggaattgat ggatacagta gatgaatata
    27421 tcccaacacc agaacgtgat acagataaac cattactatt gccagtggaa gacgtcttct
    27481 caattacagg tcgaggaact gttgcctcag gtcgtattga tcgtggtgct gttcgtgtcg
    27541 gtgatgaggt agagatcgta gggatcaaac ctgaaacaca aaaagcagtt gtaacaggtg
    27601 tagaaatgtt ccgtaaaacg ttagattacg gggaagctgg ggataacgta ggcgtgttgt
    27661 tacgggggat ccaacgtgac gatatcgaac gtggacaagt acttgctaaa ccaggttcca
    27721 ttactccaca tacaaaattc aaagcagaag tgtacgtgtt gacaaaagaa gaaggtggac
    27781 gtcatactcc attcttcaac aactatcgtc cacagttcta cttccgcaca actgatgtta
    27841 caggaacaat cacattgcca gaagatacag aaatggtcat gcctggtgac aacgtgacga
    27901 ttgatgttga cttgatccat ccaatcgctg ttgaaaacgg aacgacattc tcaattcgtg
    27961 aaggcggacg gacagtaggt tcaggtatcg ttacagagat cgaagcataa gaaacgcgac
    28021 tcgaatattt tggtaatgaa aaatgtttaa aataaaagag cggtccaaac aggatttctg
    28081 tttggaccgc tctttgttct tcaattgtat aagaagagat tgtagaagca tgaactttcg
    28141 ttttacttca gtctctttta ttcatcatga gagtgttcat ctatcggtat gcagttttta
    28201 atactttctt cgtatccatt ttttcaaacc acttattcta ccttgtgtct gctcaactgg
    28261 cgcattatca ataatcagca aagcaatcat aacatatgca atccaactat ctctagaata
    28321 tagagtataa cgtgagaccc agtttgtagc gtacttgctt ttatattctc ttaatccatg
    28381 gaaagaataa aaatgagaac caaactcgta aaccaagtat gcaatccttt cctgtaaaaa
    28441 actctttctg gaagttccga catttgaaag aggggccatc cctaaattga accattggat
    28501 atgttcttct ttcatatagg caaacaaatg caagaacaag aaatccatac tgccagaagg
    28561 tgctttttta gaatcatatc gcatcagatc aatcgttcct actttattgt tcgtgtaagt
    28621 aggcatgatc gttgcaaaag cgacaatttc ttcttgggta tttttgacaa ctgcaatagg
    28681 cgctctttgt agataatctt cagagaaaaa gcctaaagaa aacccttttt cctttcgtga
    28741 acccaaccaa ttatcagaga tatttttgaa agtactcatt tgctcagtag aaaatggtgg
    28801 ttgtaagaca tcaaatgtaa atccttctcg ttcgatccga ttcaagacag cacgagtgcc
    28861 cttcattttt ttccctgaag ttgtaaaact attcaggtct acataagctt cttcccccat
    28921 cttaatgaaa tcgtagccga attcatgcaa aatcataaca atctcttcgc ttgtttcgta
    28981 gaaaactggt aaatagcata gtcgatctgt ttcttcgata aaagcttcga ttgcttctgg
    29041 aaaatcttct ttcttaccag aaggatcacc cattacaata catttattat tgaagcaagc
    29101 gaattggaga agaacagttg gttcaccgtc tttttcatag gcaaacatcc gcttatcttt
    29161 taagaagatc aattgactat cggagtttcc tccataagtt gtaaggatct tcagggcctt
    29221 ttcttcatta aaggcttcgc caatctgttt cttttctcct tgaaggaaat gaacaaatag
    29281 aacgatcatg aaactaacag cgatgatggc caacaatccc gaaaaccaaa tcttttcaga
    29341 aggaaataag aaaaaggaaa taaaatggtg acgccgatga gggaaatccg gcagattgta
    29401 taccccaata acgatgtaaa gcaaggacag tgcaccaata atgattccat cgatcgtacg
    29461 ccactcccat gaatagatca attgttcccg aaataattcg tttttagaag caagaatgat
    29521 cagaagcaga atagacaaga aaaccaccgg tgtgaaacta aaatcactta ataaaacata
    29581 aagtaaagct agaacaatca agaagattgt aggcaaatat gctcgtttca cacgtgctgc
    29641 gatccctctg cccataatga ttaaaagaaa tcccaatagt atactaggaa attggataat
    29701 aaaatgaaat ttcaatgggt tcaaactatg aagccagcga aactctgtaa aagcttgcgg
    29761 gatagtggca gaaagtacta gcatgattcc agaaaagtat aataagacaa ccacgatttt
    29821 atgcgcaatt tctgttgcta attgtttagg gataccagaa taacgctgat caaaagtgga
    29881 accgatattt ttgaagaaaa agacgattcc aatcaaaaac ggaatgatgt agtagaacag
    29941 gcgatagagc aagatccaca caacgactat ttctcttggc acaccaatag cggacaaccc
    30001 gataatcatc attacatcga aactcccaat ttctcctgga atcatagaca cgattcctat
    30061 cactgaagca gcaatgaata atggaattgt ttgccacaga tcaatccgga tttccattaa
    30121 ataaccaaca gaaaggaaac taaacaggac accggtccat tccaacaatg aaactagcaa
    30181 tagctgtcct tgagttttaa gtgaggtacc accaaggaat cctttctttt tgaaagtagt
    30241 aaataaaaag acgacaggaa aatatagacc gccgccgatc aaccatatcc aatattgctt
    30301 caaaaaagga gcaactggcg tgaagactac aagtaaaaaa gaaagcagac tgtaaataga
    30361 aagtccagcc atcaaaaaca agaaaacttt cgataatgct tggatcacgt ttctgctctc
    30421 tttcttttgt ccatatagtt cagagcgaag ccccacacta acaaacccgc cgaaaccggc
    30481 aatattgttg atcgtattga tcagccagct tgtctcaaac aggtaacgag gattctgctt
    30541 ttgttcaagc atccgattca aaataatatc ataaccaacc ataggtaaca cagagataag
    30601 accaatcaat agcattagtc cgcttttcca tacaggtata gtggcaaacg tttctcctaa
    30661 ttgctggata gatagagttt taccgatgga catcaattca ccgacaataa tgacaatgac
    30721 agaaatcaaa aagattgttt tgaacagtcc taggtggttt ttcagccatt gtatggtatt
    30781 ttttaacaaa taaatcacct tctattccta atagttatgt ttcagaaaga aattgaagaa
    30841 cttctcgatt gaagcgttca ggatcttttc tagctaattc atgtccttgt tctttcacaa
    30901 gcacaaagga agcttttggt atagttttag ctatatacaa agaatgtttt agcttgatta
    30961 catctttttt tcccacgatg atcaaagtgg gggagttgat tttttttaaa tcattttctg
    31021 taagcccgat gtcatgcagc aaaagtttga taactaaaag atttttgcga agacttgggc
    31081 gaaataaaga gagtaaccat acccatgcat aatgaatatt actgatgact ctggcagaaa
    31141 aacgaacgcc tttaacaagc gtgtttccag aatttaaaat caatcgatga acttttttag
    31201 ggaagctgct ggcaaatacc agtgctagat ttgctccatc actaaatcca agaaaatctg
    31261 cctgatcgat tttttccagc aacatgatcg tattcagatc ctcggccatt aactgaaaat
    31321 tcaacataga tgcttcgttt gtcgaacgac catgtcctcg gctatctact agatacacgg
    31381 tatagtagcg ttcgagtaca gggacctgtt ctgaaaaaaa gcggccgctg ccgtcattgc
    31441 catgcagtaa aaagagaggg aagccttgac cgctcttttc atagtaaatt tcgctcccat
    31501 ctggcatttt tgcatatttc ttttcttttt tcacataatc acctactgtg taaagtataa
    31561 cgattatatc agtcattggg caattgtttt tactgaaaaa caacgatcat tttcgtaaga
    31621 tgtcaaaaaa tacaggaaaa ttcatttttt cttaaggcgt acacagaaat caaggaagaa
    31681 atagccaaga agataaagaa atagtaagat aaaaaaagat gtcaaaataa ctaggtgatg
    31741 aaatgaagcg aaaacgatta tctattatcc gtattctttt ttacatgatc attctgacgg
    31801 ttattggtgc ggtgttgttt ttatgaggaa gaacttatcg ttcggtaaaa cgagtggaaa
    31861 gctatcaaat agaaataaca acagctgcaa aaaattatca tatggaaaac tacgagaatt
    31921 tgatcaaggc gataatattg accgaatcaa aaggaaaagg gacagatctc atgcagagct
    31981 cggaaagtct gcatggagaa gctgagatca ttgataatcc agctgacagt attgatcaag
    32041 gtgtcaaata tttggcggaa atgatagtag aagcaaagaa acaaggatgc gatttatgga
    32101 cagctgtcca agcatataat tttgggaaag attatattgc ctatgtaaaa aatcatggcg
    32161 gagaaaacac agtagaatta gcagaagcgt attctaaaga tgtgctgagc ccacttttag
    32221 gaaatgagga agggaaacaa taccgatatt ggcggatcca gtccttgctt tacaatggcg
    32281 gctatctcta tcataatgga ggtaacatgt tttatcctga tattgtcaaa atgaatgaaa
    32341 aaataataga gacctatgaa aaagtcttta agtaaaatag caggaaatgt tcaatcatga
    32401 ataaaattaa atgaaagaag gagtgcgcaa atagtggaaa aaaggcaaaa aatggaaaat
    32461 caagaagtgg ggtacacaac caaagactgg atgttacggt ttgtgaaggg aatgtttatc
    32521 ggttcaggat ttatcttgcc aggagtcagc ggtggtgcat tagcagctgt ctttggcatg
    32581 tatgagcggc tgatttcttt tttagcccac cttacaaaaa atttcaaaga aaatgttttg
    32641 ttttttctgc ctgttggtct aggcggagtg acaggcatct ttctactttc ttttttagtc
    32701 agttttttat taggtgcgta tgaaacaacg atattatggt tttttgtcgg atgtatcgct
    32761 ggaactgttc ctgcgttatg gaaagaagca gggaaaaaag gaagagatac ttctgatgtg
    32821 atcatcatgg ttgttacttt tgttctggct tatttgtttt tattatacgg cgctcaatta
    32881 tttgacgggc aagtcgatca gaattttgga acatggctga ttgccggcgg attgattggt
    32941 ttgggtatga tcgtcccagg attgagccct tctaattttt tggtgtatat gggattgtat
    33001 aaagcgatgg ctgacggatt taaagaagta cgacttgaag tgattgtgcc gatcggaatt
    33061 ggtgggattc tttgtgttct tggattgtca aaaatcatgg attacatttt ctcaaaggca
    33121 tatagcaagc tattccattt cattttaggt gtagtttttg cttcaacgat tatgatcatt
    33181 cctaccgatt acgcgggatt gggagttgct ggggtactag cttgtcctgt tctttttata
    33241 gccggtacag cactaggttg gtggatgagc cgtttggagg aacaatataa gtaaagatag
    33301 attgataata aaaacagcac acgggtgatt caaacaaaaa ggttggcatc ttttttgtaa
    33361 aatcattcgt gtgtttttct ataaatttta taaaaacaag ttgtttttaa tcttggaaca
    33421 cgctagactt aaacacgtga ttatttttga aagttggcgg aaaatggaga aaaagaaaat
    33481 gaatggactt acacagcaag aggtagttca gaaaatggct tctggccagc aaaatgacta
    33541 ccaggaagat gcatcaaaaa gtacaaaaca aatattcagc gataatatat tgacgttatt
    33601 caattttctg aactttggta ttgggatttg tctgttattt gtaggtgcgt attccaacat
    33661 ggcgtattta gcaattattg tcgtcaatat cgttattgga atttatcaag aaatacatgc
    33721 aagaaatctt gtacggaaat tatcgattgt ttcccaatca gaagtactag tgatccggga
    33781 cggtaaagaa caatcgattt ctactaaaga gctggtatta ggagatttgg taaaaatcgg
    33841 agcaggagaa cagataccag ccgatttaca ggttatatct ggacgggcag aagcaaatga
    33901 agctcttttg acaggcgaat ctgatttgat tgtcaaagaa actggagctg aattgctttc
    33961 tggaagcttt ttgacaagcg gttctgtcat ggctgaagtt atccgagtag gtgcagataa
    34021 ttatgctgtc cgcttgacta gcgaggcaaa gactcacaaa gctattcgtt ctgaacttgt
    34081 agattcgatt cgcaaagtat ccaaattcac tagtttcgtg attattcctt tggggatcat
    34141 actatttttg gaagcactgt tcatccgcga tgcttctatc aaaatttctg ttattgcatc
    34201 tgcagcagct ttgttaggca tgcttccaaa gggtttggta ttgctaataa gtattgcatt
    34261 aacgacaggg gtaaccaaac tggcaaaaaa acgaatcctt gttcaagaca tgtattcaat
    34321 tgaaacgctg gcccatgtcg atacattatg cttggataaa acagggacca ttactgaagg
    34381 gaaaatgagt atccagcggg tagaagcact acatccgctg tacgagaaag ccatcccaga
    34441 aattatgggg acgtatctgg cagaaagcag tgataacaac atcactatgc gggctatgag
    34501 agattatttt gagctttcta atcggtatga tgtgacaaac aaagtcgcat tttcttctga
    34561 tcgcaaatgg ggcgcgatgg aatttccaga actgggagtc gtgtacgtag gagcgcctga
    34621 acgtttggtg gaagaagatc ggcttccgga cagtctaaaa acagcccaag cgaatggcta
    34681 tcgcgtactt atgttgggga tcgctccaaa tcagcaattg aacgaagaaa aaccagcatt
    34741 tgttgagccg gttgctctgt ttgaaatcga tgatccaatc cgaaaaaacg ctcaagaaac
    34801 actagcttat cttcatgagg aaggtgtgga tctgaaagtg atttctggag acaatccttt
    34861 tactgtctcc aatatcgcta gacgtgcagg attaccgaat tatgatgcgt atgtcgatct
    34921 ttctcaaatt actgaagaaa tggaagtgcg agaagctgct catcgctata cggtttttgg
    34981 acgagtgagt ccgcagcaaa agaaattgct ggtaaatgaa ttgaaagaaa gcggcagaac
    35041 ggttgcaatg acaggcgacg gtgtgaatga tgttttggcg ttaagagaag cagattgcag
    35101 cattgctatg gcagaaggtg atggagcaac acgtcagatt gcgaatctgg tattgttgga
    35161 ctctgatttt actacattgc cagaagtcct gtttgaagga cgccgagtgg tcaacaatgt
    35221 gacgaaagtc tcaggcatct tttttatcaa aacgatttat tcatttattt tatcgattat
    35281 atgtgccgtt acagcaattg gatttccgtt tatccctatc caaatcacgc tgattgattt
    35341 agcgattgaa gggtatcctt ccttcttttt atcttttgaa caagataaaa gaaaaatcac
    35401 ttaccgttat ttgcctacag cacttattaa tgctttacca aatgccttgc ttgtagtagt
    35461 gaatatcatt gcggtgtatc tacttggaaa aacattcgca tggggaaatg ctgaaactac
    35521 tactttgatg tattacttgc tgattgggat cagttgcatg gcagttgtaa aagcttgtta
    35581 tcccttcaac ccattgcgca tcttcctagc agtaacgacg atcgtaggga tatatgtagc
    35641 tgcaatgctg ttccatggaa ttttggaagt aaacttaggg ttgggagaga gcgtaggata
    35701 cttctttgta ttcatgctcg taaatattgt tcttcgagta ttgtactgga aggctgatat
    35761 tcaaaatcag ttactgaaaa gagtagcaaa ttgatgctta atgagataga aatgtgttat
    35821 acttgaaaaa gcaatgaaat atgatacaat caaacatgta taattgtgtc ctttaaaatc
    35881 gcactgattt cagttagtgc gattttttac cggttattct cctgaaatat cttctgttaa
    35941 acccaaaaga tatcaataga gcagggggtg aaaaaatggc tcaacggatt cctcaagagg
    36001 ttatcgaaac agtacgcagt caaacgaata tcgttgaggt gattggacaa tatgtccagt
    36061 tgaaaaagtc tggtaaaaat tacttggggc tgtgtccttt tcatgaagaa cgtacaccgt
    36121 ctttttctgt tgcagaagac aagcagattt ttcattgctt tggttgtggt aaaggcggaa
    36181 acgtgtttac ttttcttcaa gaactagaag gtctaagttt tccagaagca gtggtaaaag
    36241 tggcagactt cgaacagata ccgttagaag atcaatggcg tcagcgtact atagctgtcc
    36301 aaaatcctga atctgctacg gggaaactga ttgctgctca tgaaaaagca gcggaaatct
    36361 atcatcacat gctattgcat acaaaagctg gacagccagc tttagaatat ttgcaaagtc
    36421 gtgggttgtc tttagaatta attgaagaat tcaacatagg ttttgcacct aatgagcgtt
    36481 cttttcttca gcaagtattc aagaatgaat caatttcaaa tgaattgtta gaacgctctg
    36541 gattgtttgt cacgcatgat gatggccgta tgtctgatcg tttttatcaa agagtgatgt
    36601 ttccacttcg taattctcaa ggccagacga tcggtttttc aggacgctgg cttgcacctg
    36661 aaaaagggca ggaaaaagat cagcccaaat acttgaatag tccagaaaca gaactgttca
    36721 ataaaagaca agttttattt aatcttgata aagcaagaag cgatatccgg aaaaacggag
    36781 aaattttgtt gttcgaaggg tttatggatg tgattgctgc atggcaggct ggtatcaaaa
    36841 ctggattagc ttctatgggg acaagtctaa cagctcaaca gatccaacaa atggaaaagc
    36901 tgacgaaaga attggtcttt tgctatgacg gagacaacgc aggttttgaa gcaaccaatc
    36961 gagggattga attgcttcgg caaaacagtc gattagcact ttctgtcgta gtcgttccag
    37021 aaaagcttga tcctgatgaa tatctccgta agtatggaga agcatctttc caagaattag
    37081 tggctcatgg gcgcgaaaca gtctttactt ttaaatcacg ttatttaaaa caagggaaaa
    37141 atttagataa tgaaaaagac aagatcgaat acctcgaaga attactagtt gaacttagcc
    37201 gagttgtttc accaatcgaa caagatatgt atctatctca actgtcaaca gagtttcaga
    37261 tcggcagaga gacgatacaa aaacaactgc gcgatcttcg aaggacaaat cagcaaaatc
    37321 gtcaagaacc tcaggaaagt caacacactc aggttacgag acaagaaact gcacggaaaa
    37381 agagaccttt gacgcaagta gaaaaggcag agcagattct attatatcgt gcatttaaag
    37441 aagtttctgt ccgtaatatt ttaaaagaac gagaatttca gtttattcat gatgcatatg
    37501 cagaagttta ttttttattc gatgcatatg tctcacaaca ttatgaattc aaccttgcag
    37561 agtttttaga ctttttgcaa gatgaaaatt taaggcggtt ggtggtggaa atcgaatatt
    37621 taccggtggc agaagaaagt tcgccacgag aaatccaaga cttgctagat gtgatcagca
    37681 aatctggctt agctgatgaa ataacattaa aaaaacaaat gcagcaagaa gccagacgaa
    37741 ctggaaacaa acagcttgag cttgaattga cgattgaaat catcaattta acgaaacagt
    37801 taaaacaagc caaatagcta ctcaaggggg gccttctttt atggcaaatg gaacagataa
    37861 aaaaacgtat gaagcagcag tagcagcttt catcaaagaa aacaaaccca aacgacaagt
    37921 tgtatatgat gatttatcca atcagcttgc tacaccattc actttgaatg cagatgaaat
    37981 ggacaaattg atccaaaaga ttgaagacgc aggtatcagt gtggtggatg aaaatggtga
    38041 tccatcaatt cacagcttga agagtgctga gaaaaaagct gaacaagcaa aaacagaaga
    38101 tctttctgcg ccaaccggtg taaaaatcaa tgacccggtt cgtatgtatc tgaaagaaat
    38161 tggccgtgtc tcccttttaa ctgcggaaga agaagtagcg ttagcattga aaatcgaaga
    38221 aggcgaccaa gaagcgaaac agcgtctggc agaagcaaac cttcgtttag tagtaagtat
    38281 cgctaaacgt tatgtaggac gaggcatgca gttccttgac ttgatccaag aaggaaacat
    38341 gggactgatg aaggcagttg aaaaatttga ctaccgcaaa ggatttaagt tttcaaccta
    38401 tgctacatgg tggattcgtc aagccatcac tcgagcaatc gctgaccaag cacgtacgat
    38461 ccgtattcca gttcatatgg ttgaaacaat taataaattg atacgtatcc aacgtcaatt
    38521 gctgcaagac cttggaagag aacctacgcc agaagaaatc ggtgcggaaa tggatcttcc
    38581 aacagaaaaa gtccgagaaa tcttgaaaat cgcgcaagaa cctgtttccc ttgaaacgcc
    38641 aatcggtgaa gaagatgact ctcacttagg tgatttcata gaagaccagg aagcaacaag
    38701 tccagcagaa cacgcagctt atgagttact aaaagaacaa ttggaagatg tactagatac
    38761 attgactgat cgggaagaga atgtccttcg cttacgtttt ggtttagatg atggccggac
    38821 gagaacattg gaagaagtag ggaaagtatt tggtgttact cgggaacgta ttcgtcagat
    38881 cgaggctaaa gcattaagaa aattgcgcca tccttctcgt tcaaaacaat taaaagattt
    38941 cttagaataa gcgtggacta ttgaccagaa gagaaatcag taaaactgtt tggtttattt
    39001 taaaagaaaa aaagcttgag actacgcagt ctcaagcttt tttttctata ggaaggaaat
    39061 tcattcatta tttt
//
LOCUS       DAFEKH010000025        36887 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.026, whole genome shotgun sequence.
ACCESSION   DAFEKH010000025
VERSION     DAFEKH010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36887
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.026"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..222
                     /locus_tag="LP386_001416"
     CDS             <1..222
                     /locus_tag="LP386_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HBL1918657.1"
                     /translation="EQFCELYAYPQGTVASWITRQRRIKSLPASFVYDLSLASSMNMT
                     DVYEKLLILENEYDQFNSNQQRKVKKQID"
     gene            448..1266
                     /locus_tag="LP386_001417"
     CDS             448..1266
                     /locus_tag="LP386_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBL1918658.1"
                     /translation="MDTFQGTTFTVGNFKGGVGKTKIVSMLAYDNAMIRNRKTLIIDL
                     DPQANLTQVIARTFGITDIKTTITNGVANGELASSIIKVNENLDLLACDTSFRSFSAF
                     ANKHENELDQVTVLKKLLLPIKNNYQEIFIDVPPTISEFSDNAMAASDYSIISFQTAE
                     ESLEGVNKYVNYQKFMVDRYDLDLQIIDIVPCMVEPNDDFDEEILEEAIEKYGTVVSK
                     NLIHYQKRLRRYSKIGIHLRKYKNGNFDQWDYKAHQVFINILAELDARQEFLNK"
     gene            1285..1692
                     /locus_tag="LP386_001418"
     CDS             1285..1692
                     /locus_tag="LP386_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918659.1"
                     /translation="MPKDFDIPKMMENGEFEPLLPNNKRQDVKISGEYNFSNSALSNT
                     RNITLKKRGRPVSIPDKRNKVSVPKKISPALNSKLSILQDYMTELQSEKGRISFEKIV
                     NTLADSYIQHRLGVAKEEHIREEIQEEFEKLPK"
     gene            2012..3097
                     /locus_tag="LP386_001419"
     CDS             2012..3097
                     /locus_tag="LP386_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBL1918660.1"
                     /translation="MSTENQSQKMIIKNWGYKATNVYIEKYYKFPSFLIQNSKYSKMK
                     DSSKIAYMLFKNEFRRALHEKWIDDDGLLYLEFTQADLMDKLNCYQGKVKTILNELET
                     YNLISVVKGEFNPKTKKNEKNKYYLLQPEISADDLFIQNSFDDDLSETIVKSTSSRNA
                     EIARREETAKTLDNTGNAEIARREKTAETLDNTGNAEIAQDYYINKSLDTKRHLKDTE
                     TDQLQNQVLLDNFVEIMKEDSINTFVPEKVLSLIKTFSNTYEEAQQTVTTIHKAKHKA
                     EELEKTVVVYEELESYGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFIEK
                     AIAAKLANEQRETFNELPTVSTENWLE"
     gene            3934..4266
                     /locus_tag="LP386_001420"
     CDS             3934..4266
                     /locus_tag="LP386_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HBL1918661.1"
                     /translation="MSYTGILSLEDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            4857..5186
                     /locus_tag="LP386_001421"
     CDS             4857..5186
                     /locus_tag="LP386_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918662.1"
                     /translation="MIQKFAKMSKTAWIEKLENDLSVMRLAPKKFKREIAEKEAILSV
                     LNAVDDKCPVKISFSDIATIIEGIYYGEVDEEISSTKDLLDFLDKNKDTFIVLTDYEE
                     VTTNEKL"
     gene            5173..5514
                     /locus_tag="LP386_001422"
     CDS             5173..5514
                     /locus_tag="LP386_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HBL1918663.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLTDDNGDELSVEDTWSYLSDYIVSV
                     EIIEFVADKEE"
     gene            5628..5867
                     /locus_tag="LP386_001423"
     CDS             5628..5867
                     /locus_tag="LP386_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918664.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKDVFKSLSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            5934..6173
                     /locus_tag="LP386_001424"
     CDS             5934..6173
                     /locus_tag="LP386_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918665.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKMMKQKHLKRLSVMQYINDMKIT
                     GKEKACLLGSMKNFEQLRRTYVKTGSNCQLLLEVS"
     gene            6300..6989
                     /locus_tag="LP386_001425"
     CDS             6300..6989
                     /locus_tag="LP386_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HBL1918666.1"
                     /translation="MNKNNKTLFNPYVGVIIVFLLFSYFAYQGYQKDKIAEKVDGVTK
                     TIHIQEQAKTYQDNLTSLTDISKRQLITNQKQALEKDLKGEIAGKLVFSSTGFILPVF
                     QGANSDTLSLGVASTYYLDTEMGNGNYILAGYNVDTPSVLLSDMTDLSEGEEIDLIDA
                     HYKYQYEVSKRGKISDYSQVVQSKENNSFLSLPKAGKKPLLTLLAFQANNMKKCDVIQ
                     CELVNVEKINK"
     gene            6995..8161
                     /locus_tag="LP386_001426"
     CDS             6995..8161
                     /locus_tag="LP386_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HBL1918667.1"
                     /translation="MSHIQELVEKLINKMSAIFLLLLVSILYLIWTVGLNPPTILFIY
                     DNAAQLVTFFVGCLFLLNLYKVKRNDLFFIAAGILFYLFFSFFRSYRGDTFYGDLIVP
                     TIIAIILIVKWTKFTVIDRSLYLVVFYVFLLVTVYRVFTEIPVPEGQSIWNPSNKLSD
                     IWINTNTIGSSLMTLALLITGFASSFGKWYMRLLSLPALILAGATIWVCQSKAALYAL
                     VIFIILEILPKKVFRNTHLSFWMYAAVSVLALPISYFAAMSDKVHLFTGREEIWRKFY
                     ETLGEKTGQIFVGMKPFFFHRGNQILGNHNTYHALVNHYGLIGFVLSIILLLSFLWLL
                     VRKRELTNGQLTFLWAFLAIMCQSFMEETLTTISWVPIVFLMLAMATHQYKTTR"
     gene            8243..8914
                     /locus_tag="LP386_001427"
     CDS             8243..8914
                     /locus_tag="LP386_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HBL1918668.1"
                     /translation="MKKWLFGFLGVALIVVCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            8967..10943
                     /locus_tag="LP386_001428"
     CDS             8967..10943
                     /locus_tag="LP386_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBL1918669.1"
                     /translation="MAINRYVKKAGMIVGMLGIIAGCFQGYRAYAEDVTQKTPPERVN
                     ITVHKLMYDQSTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PTEDSDLTNAKVDEIVKDVEDKGSNSEYVKNATNKITSAVDENGEITFADQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDNTGSGFLKDIHLYPKNIVSKLSFELTK
                     FGDDGTAQSKQTPLKGAKFELYKGEPGKGTKLGELVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGEEHSFQIGDAVNYQGTIHIPTDIAGGTDGITVNGVKSETSPYSVFKWGDTA
                     GKGLSYVAEKADIKVTNNDGSVVLKENTDYKIENSDSGFVIDFIVNNGQVSDTVANLH
                     GQDLKMTYNMFVNDSAEIANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLTDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGDYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQSYVLISCLLLGAGAISAVVYFKKKA"
     gene            10956..11708
                     /locus_tag="LP386_001429"
     CDS             10956..11708
                     /locus_tag="LP386_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL1918670.1"
                     /translation="MIIRHPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQ
                     QIAAIDRTGTAAETDSSLDVAKIELGDPVGILTIPSISLKLPIYDGTSDKILENGVGI
                     TEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIE
                     EVQKDELQRNFVTYLEPNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEEN
                     KKQKLSWKWLLGSTVFLSVMIIGSLFVYKKKK"
     gene            11724..12485
                     /locus_tag="LP386_001430"
     CDS             11724..12485
                     /locus_tag="LP386_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918671.1"
                     /translation="MRNRKWLFVCAAALFSFTAYTQLTFADRQESTDSTEQTIQTSDS
                     STIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGQKLEKQEGV
                     NGAKFSVYDVSDILQKMDVKDLTTDQIESQLKDRVKKLSSDQLKLISNGETKTIDQQT
                     GVFEFSVEVQANQKQAYYIVNESSPENISNSEDILLLTPVSDKNGEFLKDVWIYPKSE
                     ASQPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            12498..12758
                     /locus_tag="LP386_001431"
     CDS             12498..12758
                     /locus_tag="LP386_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918672.1"
                     /translation="MKLIKLLLFNFSCLTAVFLYCGLLFSKLSILPSYQLYLMRILNI
                     PAASMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG"
     gene            12755..14845
                     /locus_tag="LP386_001432"
     CDS             12755..14845
                     /locus_tag="LP386_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBL1918673.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKTNITVNGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYP
                     SFQKEYGETNLVLEGVTTNTKVNIDYGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNLL
                     DNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATYEDG
                     SPVQFSGDTFISFNSLNPAGGKSTDLKGEYAHYDKMNTTDWYVRKDTVLSEFKSFYNN
                     LNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQT
                     WFTLSSATIFSVVPDQPEKTGVDKNGNNVNDKMLQVGDTIQYRIKQKVNRLGVDLLAV
                     YDRFELIDNLPKEVNYVDAHVESGTNKKFDVSGEVTYDKTKHQVKYAAKADTLKNRMK
                     YNGETYELVINVKVNELANQNSVAKNQGTSIINKVEKDTNIITVYFPKIPVKEVQQNG
                     KDVNGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDPIEARLT
                     YKEGSAQVIDKSKGKDITSEGTLTYDSNSRTLKWEASADFLNNNLLDGREIQLIFTAK
                     TPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTILAVSLLL
                     LVLATFGYAVLKFN"
     gene            complement(14881..16938)
                     /locus_tag="LP386_001433"
     CDS             complement(14881..16938)
                     /locus_tag="LP386_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HBL1918674.1"
                     /translation="MKLLNPKTVIAIGTFAATVALAGSADAASTNVMYRLYNPNNHEH
                     FYTSSTKERDHLVKIKWGNYEGPAWEAPTSGGHLVYRLYNKGLRDHHYTASWDEVKWL
                     TKNYGWTYEGPAWRSAEKNNKPIYRLFLPGVTSGSHHYTASWKEVQWLTKDYGWKYEG
                     IGWYGADTSKPKVNKSALEALYTSVKGTKKGDYTDNTWNAFQTALNNAKKVLNDSKAT
                     QKQVDSAKNTLDSAYKGLKKKPAPTVNKTELQALYNQVKSTAKGDFTEGSWNNFQTAL
                     SNAKKVLDDSKASQTQVNNAKNSLDSAFKGLQHKPKPSEYAVTVRHMNRQTGTLLKEE
                     HVSVKAGTSYTAKARTDLTNFEAPQYQVNGNETQTQTINTNTTFTFYYDEVFLVEVKA
                     RPNKVSDTDPNIQELYNYSKSYPVVYGQSITIEAPMFTNFVLDPRESSSNTVTLNNVT
                     SNQGINFAYTHQYNVTVNHINVDTNAVLSTETQTVYEGDSFSTSWKNMTDQNYFLCRN
                     DDSSVTVDKNGQRVINNVDQNRTITFKYKNISLSDLNNYVRQKELAWLNSYRQQNGVA
                     PMQFNDIVQQAADIRAKELQVSFSHYRPGGGTFQDLLESLGCYGAKGENINSFYLYVD
                     EILSDTGAVNAMVMWKDSAAHNANLLYNNQSIVGLSHAYEVSADGSLSSDNVFISANP
                     IFK"
     gene            complement(17083..17274)
                     /locus_tag="LP386_001434"
     CDS             complement(17083..17274)
                     /locus_tag="LP386_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918675.1"
                     /translation="MYADKEKIEWLLFETGKTAYEISKHSSVAESTIADLIKKKSAIE
                     KMRFDNAAKLTKYAESISS"
     gene            17462..17917
                     /locus_tag="LP386_001435"
     CDS             17462..17917
                     /locus_tag="LP386_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918676.1"
                     /translation="MKKLIMVFTSLIAMIVILGGCGSEKNKQDSQDNGVLKPGTVWKE
                     EVGGLVHNLKIIDDTTWEYSESVWHPEQVQITVEKLKDYKGLERYKVIDSGGVDLFIG
                     KTALIVPYNKDGLETFKFIPTNEKEHRDKSEILKEYSTKSGYKLQKTSE"
     gene            17914..18156
                     /locus_tag="LP386_001436"
     CDS             17914..18156
                     /locus_tag="LP386_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HBL1918677.1"
                     /translation="MIASLFIYPEGGIAVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            18174..18476
                     /locus_tag="LP386_001437"
     CDS             18174..18476
                     /locus_tag="LP386_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918678.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQGAATSLKNNLMIFAAVAA
                     VASIVLGGIFFFFGRRGAENGKMHVGYVLMGVGVILAAASIVVSLFGMFGQTPQGL"
     gene            18545..20599
                     /locus_tag="LP386_001438"
     CDS             18545..20599
                     /locus_tag="LP386_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918679.1"
                     /translation="MYFTISGNTKKDKELIKKATKKVGKRTAFLPKTIKYSVIETEEQ
                     LHVLGQVLEQENQSSVKLTLTLHDKEGKIEKAGTEYVFGPLDYQISEGFYPTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVSQVSEVEVNDEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETAEVEVDLVEA
                     NEEPTWTEGDSQEYIEPLISEEVEKNETEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWERTKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCIE
                     KINNFTKTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMERHGQIQQELQAQIPKWKKEYEIQQQELKEQEEKQRQEEKEREQLELKKREQH
                     LAEQKVAIEKQRLEQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPVAAVQTPVNNQ
                     ANLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTASIKEEAQE
                     QARKEYEQQLEELLNRTNQSTAESSMENSKESDPSKAKEGSSDSTVHSNTSESSESNE
                     VK"
     gene            20599..23211
                     /locus_tag="LP386_001439"
     CDS             20599..23211
                     /locus_tag="LP386_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBL1918680.1"
                     /translation="MRIRETTRRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     QKIFYSGLAYLPLNYVVTRIPEAFHRFEIIPGSLQGVNIFQLQEMPQLFHFDSTGFWN
                     PLTPTTSLGTRLVVSTICVVPAVLMGLKMDMWFRPLADGQKGDNRLKTLKEIQQIYPQ
                     IPESKGSFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     RQSSMVVNDPKTELYVASKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPENEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSIGFPKYLDLKLHESLLNQRIVVEFYHKGK
                     KFHEERVKVGYRGFCEINFDCHLEQGDHVCLKYNHQGKQYVAWYEFSQKVLKDEEGKI
                     VYRKKRGETHLPELEKEAVLTLDEKKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNML
                     WDLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENS
                     TINSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNH
                     GETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGL
                     HDQLEEKNEENMFYKIVQSFENETAKKLLIQFYEEQATDRLQEYVEKLIKNEEISEMI
                     RKRLLLEAEKAVKE"
     gene            23208..25586
                     /locus_tag="LP386_001440"
     CDS             23208..25586
                     /locus_tag="LP386_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918681.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDADPKTVTKVLQDYGNYLQYQDV
                     FSWICNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNELFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKNFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PDQAKKMSESSDISTVQKDRLKALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYRRY
                     ISSPGIILAGESSLSVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSAIE
                     DISQSFLLLAFTILELRIYTLMLSGIGDLHAVGKINGFLYVVALIVLTIALFKGSQSV
                     TKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGFGH
                     RKDITHDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGTVE
                     DLTEKAKDTLEEKLDGTRAKEFAEAVKNPSEALEKQKEKASAVKEGLKDAYGEGQVNA
                     AVKANTTSEKENQEGAAIPSAKDHQDELHSNENSIGEKDSEEGQHGQLPKTDPEQYRY
                     KSNINSENEKRISDLPKRNQEVQTDEDSIDLPNDNGIEVGTEKSTKIGLPKTQNLPMK
                     DSRLNQFKENDQSFVHQSPAGTVQMKSSRLPENGNLTTVSYNLAESGETENASVQNIV
                     TKEAAPKPINKVHNGYRPANVAFTAPTKINVTRETKNRNNELKEQLLKDIKP"
     gene            25647..26189
                     /locus_tag="LP386_001441"
     CDS             25647..26189
                     /locus_tag="LP386_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918682.1"
                     /translation="MEDILIATFITALGAFLTIFVVTIKGFKDTDSLQKDHQSILDGQ
                     KTHTESIIVHLSEGFTYLKDAMPTFTVKLTEIFHSVEQISSELKEQRQQKDRQLGSLN
                     FRQETIQESLENVNRLNDEMQRVHLENEELRAQNYDLIQKKRNLEQKIVELKEENRQL
                     NYQLRRGKNRSRDLGNELEL"
     gene            26267..26599
                     /locus_tag="LP386_001442"
     CDS             26267..26599
                     /locus_tag="LP386_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918683.1"
                     /translation="MDKYIHMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKIVNNLV
                     HLPLFFALLNYGLWLAIALVIVWRPYNNPGQRQIFAIIESIFFTDKNHYHALDPNRNY
                     HGTYKEDE"
     gene            26600..27193
                     /locus_tag="LP386_001443"
     CDS             26600..27193
                     /locus_tag="LP386_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918684.1"
                     /translation="MRVKGQNSVDKKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLRKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            27215..29239
                     /locus_tag="LP386_001444"
     CDS             27215..29239
                     /locus_tag="LP386_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HBL1918685.1"
                     /translation="MLDVIKTAFSTQSNQKVIDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLAFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNAINPDFIETVNYVTNFQ
                     REMRKVEAMTVLATQSPQEMVPENMSSDNFSKLKKVFEFSSTKIFMRMDESILRHIEG
                     LVGKSMTNSELESIPQQNQGDAVINFGSKETIRVHFSPNKRQLKLFDGGK"
     gene            29239..30438
                     /locus_tag="LP386_001445"
     CDS             29239..30438
                     /locus_tag="LP386_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBL1918686.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWVFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYKLL
                     PSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKFPN
                     SKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSAYYKNCMSII
                     NTNKLMEYDEFAIKHWREGGGTGGTITGSWGNPFPGSSLDKNSFSGGQLFGKNPGGEF
                     RPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVYQE
                     FANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDPLP
                     FLNSSKK"
     gene            30454..31098
                     /locus_tag="LP386_001446"
     CDS             30454..31098
                     /locus_tag="LP386_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918687.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQETNTYKIEEVAK
                     NASDKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPVDDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVTDFSYFTR"
     gene            31109..31915
                     /locus_tag="LP386_001447"
     CDS             31109..31915
                     /locus_tag="LP386_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918688.1"
                     /translation="MSKKKGARQRFKKRKSYLRWLGIFMILGFLILASPIYTHKKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIKAKVIKVSDDYFVVKLAHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIFYIH
                     EDKVKDHVKDEDYEQHAINYKVKGYKKEQKAAQKQIESFQATIDLNEELVKKLKDQLP
                     YQVAEDQENTENKINSYQQEIETSKTQMKDQEESIQKLQEKIDRMTKENI"
     gene            31938..32167
                     /locus_tag="LP386_001448"
                     /pseudo
     CDS             31938..32167
                     /locus_tag="LP386_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            32188..33261
                     /locus_tag="LP386_001449"
     CDS             32188..33261
                     /locus_tag="LP386_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4199 domain-containing protein"
                     /protein_id="HBL1918689.1"
                     /translation="MKKTYQKFLWISYIVLFIVGFLVSVSVIVGTLFLLFSDEDLVLK
                     GLMSTLSCVMLLYLCIQINEIMPPHWQEKKKEFKEEIEIKSNDWIEYTWLPLKRNSKR
                     KEFWALQLWPIGKLFIYMASLMVTLIGYLVVVYGVAYYLLSEPKQIAASNIFTAVMTL
                     MCVMCFSIFSYLLVQFIRQNLTMSKLFKSLLDLLILGSMLTTLTDRFEQSEKTVEGIK
                     NFLTTIDQFINGYMYLFEVGFILTLFGCVFIKLIKRSIEKEMVIDLIPTLSGYEYYVD
                     FGKYEELIHTDIVHTSIHEVTVKGIRSTLKDGQETKTIDRRKEVYNFYKVEASLRYGI
                     GKLRLDGSNIQQNKPYVLGKVVI"
     gene            33305..33574
                     /locus_tag="LP386_001450"
     CDS             33305..33574
                     /locus_tag="LP386_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918690.1"
                     /translation="MILLYRIVLIVGTELKILKKEQLFKVKEHHNQLLCIKTGTMNIQ
                     YRTEYLELTNQTDFLSIREQHKQEKLMATYSQLIDEWEQFKESKT"
     gene            33850..34125
                     /locus_tag="LP386_001451"
     CDS             33850..34125
                     /locus_tag="LP386_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918691.1"
                     /translation="MEVKIRDIDEKTIQRIDRRCIELSERTGTKWSRNRYLKVLIEND
                     FDHELMDHRKDQFDRLLEKFVDIQTYNTKILEEYIATNNQLIALLIE"
     gene            34167..34589
                     /locus_tag="LP386_001452"
     CDS             34167..34589
                     /locus_tag="LP386_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918692.1"
                     /translation="MAKATRKHVYLYDMHIEVLDEIISTHEDISNYSEAVRHLCMMYD
                     PKIEEKINPIQIKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKPINESVHARVDPFDPTKFLKR"
     gene            34609..36201
                     /locus_tag="LP386_001453"
     CDS             34609..36201
                     /locus_tag="LP386_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918693.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEKERRTPDE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMEHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQREQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKMGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEVENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPDKRSEWHYGDEKRTKLSPYTREKLDELTKYVLTKEPEYQEYIQ
                     ISKSLKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKKQDSQIKPLIESMD
                     QMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            36222..36557
                     /locus_tag="LP386_001454"
     CDS             36222..36557
                     /locus_tag="LP386_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918694.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLRNEQF
                     DPNQFLVVEYSATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKSI
                     EESISLTEC"
     gene            36703..>36887
                     /locus_tag="LP386_001455"
     CDS             36703..>36887
                     /locus_tag="LP386_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918695.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQSGDI
                     LTLNLTTKTFVDAAEDYP"
BASE COUNT        13398 a         5627 c         7367 g        10495 t
ORIGIN      
        1 gaacaatttt gtgagttata tgcctaccca caaggaacgg ttgcaagctg gataacccga
       61 caacgtagaa taaaatcatt acctgcttca tttgtatatg atctaagtct tgcttctagt
      121 atgaatatga ccgatgtata cgaaaagtta ttaatactag aaaatgaata tgatcaattc
      181 aattcaaatc agcagcgaaa agtaaagaaa cagatagact agaatagcta ttttcgaaaa
      241 gcaatattta aggtataagt tataccttta ataataaaag tataagttat accataaata
      301 tatatggtat aacttatact tttattatta aaaaccgcta tatccaaacg tttttagata
      361 ttattattta agttatactt ttaatgttga ccatttccga tatataagtt atactttaat
      421 tatcaattaa agattgggag gatttacatg gatacttttc aagggactac atttacagtt
      481 ggcaatttta aaggaggagt aggtaaaact aagatagtca gcatgcttgc ttatgacaat
      541 gcaatgataa gaaatagaaa aacgcttatt attgatttag accctcaagc gaacttaaca
      601 caagtcatag caagaacttt cggtataacc gatatcaaaa ccactataac aaatggtgtc
      661 gcaaatggag aattagcaag tagtattatt aaggtaaatg aaaatcttga ccttctggca
      721 tgtgacacta gttttcgatc attctccgct tttgctaata aacatgaaaa tgaattagac
      781 caagttactg tcttgaaaaa attacttctt ccaataaaga acaattatca agaaatattt
      841 attgatgtac caccaaccat tagcgaattt tccgataatg ctatggcagc ttcagactat
      901 tcgataattt catttcaaac agctgaagaa tccttagagg gagtcaacaa atatgtaaat
      961 tatcaaaaat tcatggtcga tagatacgat cttgatttgc aaattataga tattgtacct
     1021 tgtatggtag aaccaaatga tgattttgat gaagaaatcc tagaagaagc aattgaaaaa
     1081 tacggaaccg tggtatccaa aaatctcatt cattatcaaa aaagattgag aaggtattct
     1141 aaaattggta tacatttaag aaaatacaaa aatggaaatt ttgatcaatg ggattataaa
     1201 gcacaccaag tatttataaa tattttggca gaactagatg ctagacaaga gtttttaaat
     1261 aaataataag gagttgcata agtaatgcct aaagattttg atattcctaa aatgatggag
     1321 aatggtgaat ttgagccatt attacccaat aacaaacgcc aagatgtgaa aataagcggt
     1381 gaatataact ttagcaatag tgcattgagt aacacaagaa atattacatt gaaaaaaaga
     1441 ggccgaccag tttcaattcc tgataaaaga aacaaggtat cagttcctaa aaagatctct
     1501 ccggcattaa atagcaaact ctcaatttta caagactata tgacggagtt acaaagtgaa
     1561 aaagggagaa tttctttcga aaaaattgtt aatacattag cagactcata tatccagcat
     1621 agactaggag tagcaaaaga agaacacata agagaagaaa tacaagaaga gtttgaaaaa
     1681 ttaccaaaat aatttttttt catgcggtat tcaattaaag tataagttat actagataaa
     1741 tgaatattaa agtataagtt atacattaaa tatttaaggt ataacttaat aaacaacgtg
     1801 taaatttgcg attaaatcaa cattataaaa ttattattta aagtataagt tatacattat
     1861 ttgtatttaa agtataactt atacttattt ttttaatata taacttatac cttaaatact
     1921 gaaagtgttt tattcaccct taatacatgg tatagttcac ttgttgaaaa tcctgaatat
     1981 atacaagttt ctaagaagaa ggagaaattt aatgtctaca gaaaatcaat ctcaaaaaat
     2041 gataattaaa aattggggat ataaagcaac gaatgtttat attgaaaaat attataaatt
     2101 tcctagtttt ttaattcaga attctaaata ctctaaaatg aaagacagct caaaaatagc
     2161 ctatatgctt tttaaaaatg aatttcgtag agccttacat gaaaaatgga tcgacgatga
     2221 tggtctatta tatttggaat ttacacaagc agacctaatg gacaaattaa attgctacca
     2281 aggcaaagta aaaaccattt taaacgagtt agaaacatat aatttgattt cagtcgtaaa
     2341 aggagaattt aacccaaaaa cgaaaaaaaa tgaaaaaaat aaatactatt tacttcaacc
     2401 tgaaataagt gccgatgatc tttttattca aaattctttc gatgacgatt taagcgaaac
     2461 tattgttaaa tcaacctctt ctcggaatgc ggaaatcgca cgtcgagagg aaactgctaa
     2521 aacccttgat aacactggaa atgcggaaat cgcacgtcga gaaaaaacag ctgaaaccct
     2581 tgataacact ggaaatgcgg aaatcgcaca agattattat attaataaat ctttagacac
     2641 taaaagacac ttaaaagaca ctgaaacaga ccaattacaa aatcaagttt tgctagataa
     2701 cttcgttgaa atcatgaaag aagacagcat aaacacattt gtaccagaaa aggtattaag
     2761 cttgataaaa acattttcta acacttacga agaagcccaa caaaccgtca ccacaataca
     2821 caaagcaaaa cataaagccg aggaacttga gaagacggta gttgtgtatg aagaacttga
     2881 atcttacgga attgatgcgg ataaaggatt atatatgacg ttgctgaaag cttatcaaaa
     2941 acaaaagact gagaaagtaa ataatttgca gaatttgatt tttgtgtatg taaaaaactg
     3001 gtttattgaa aaagctattg cggcaaagct tgcaaacgaa caaagagaaa catttaacga
     3061 attaccaaca gttagtacgg aaaattggct agagtagttg ataaaaagcg aacactataa
     3121 aaatgatcaa ttttaaatta gaactttttt acaattttaa ttttattaca aatgttacaa
     3181 ataaatagtt attattccgg agtttttaga ttaaaagttt atgaaaacaa tcacaaacgt
     3241 aggttttaat gtcataatcg ttagatattt tagttatttt tcattcaaaa aaacagggaa
     3301 ctagtgtttg catatgtatt tttttgagtt ataataattc atgaagagag gtaattcact
     3361 tatttaccca agctgaaaag cctgatatta cttcttttca ggcagtgctg ctaatattca
     3421 attacacttt tttgtataaa tttagttgtt ttaaatttaa ttgtctgcta tgcttgtgat
     3481 gaattgattt tcgttctgca cttttggacg ataaatttgg acaattgaaa atacaaaaaa
     3541 aagaaaggcc ctgtgagact cggaaggcta ccaaccttcg tcgacgtcca caggtggcat
     3601 taagtctata ccccttaatg cgtttacctt tcagtgttac ggtattaccc gtaacggatt
     3661 tagtataaca gatattcaaa agtgatacca ctttttttgg ctgtgttaag gttaaaaata
     3721 cgtgatatta cgatgaatct atgcctaagc ataatgttat aaaaatgtcc gtggggctct
     3781 ttgccgtatg acgaacgctg aaattagagg gaacgcatgt ttgaatgcgt tccctctttt
     3841 ttgtttgtca tgaacgaaaa tcaattctct atttttgaaa aataacaaga aaaacttgtt
     3901 aaaaatattt aaagtaagtg ggtggattat tttatgtcat atacaggaat tttgagtctc
     3961 gaagatattt gtcactacgg taaacggtgt accgctacag aaaagatcac gaagaaacta
     4021 tcaactggtc aaagtaaaac cgttgtgcag tgtaagaaat atataatcca gaaagacaaa
     4081 gtctcagaag aaatgattta ttacattggg aaacaaaaac aaataatttt aaaagatcct
     4141 atccctttaa aagagctata tccaacaatc aaacatgttt atgaccaaaa cggtgtactg
     4201 attggtcgaa gaaaaaatgg agtcttgcgt tgtaccgcaa aagggatggg gcgtttaatc
     4261 agctgaattg atcattctca taacttgtat tttatcgttt ttcgcttgct tgaaaatatt
     4321 gtcgagactt ctaaaggaac ttagaatcac tagaaaaata aggagtagac ttgatctatc
     4381 aacaattccc ttcggggagt gacggggtag gtttttacga ttggtaacgt aaaaaattgg
     4441 tcaatcgagt aaatgccctt gtttggatag tggtgaaatg aatttgtgta aataatatgc
     4501 acagagtaaa caagagggaa tttagaagtt agacaagtta gaatagcgcc tagattaatc
     4561 atgagcagct actaagggat ctaggctttg acgcaaactc atggaataag gagtaggtct
     4621 tctcgtaatg gggaggacgc acaagaaatt gtgtcgtgtg ctgcagtaca tgtagatact
     4681 tgcgaggacg ttgatcattg gatcaatcga gcatttaccg ctgtctacta gggtttctcg
     4741 tttcggacgc cataaacgag tcgatttatt ttatatattt ttgagtgaac gaaaaacgat
     4801 aaagatattc gttatgaagt aaaactaatt tagtagatag caaaggtggt agaggaatga
     4861 ttcaaaaatt tgcgaaaatg agtaaaactg catggattga aaagcttgaa aatgacttga
     4921 gtgtcatgcg attagctcca aagaaattca aacgagagat tgcagaaaaa gaagcaattt
     4981 tgtcggtatt gaatgcggta gacgataaat gtccagtaaa aattagtttt tcagatatag
     5041 caacaattat cgaaggtatt tattatggtg aagttgatga agagatatct tctacaaaag
     5101 atttattaga ttttttggat aaaaacaaag atacctttat agtactaact gattatgagg
     5161 aggttacaac aaatgaaaaa ttatgatccg aatatacgat tgggcacaca tacgattaag
     5221 gtttctttcc aacgttggga ttacaaagga tttgtgacgt ttagaagagg cggaaattgt
     5281 aaaggattag atgttttagc attagacgag gatgatttat acgatcaaac attgactgat
     5341 aatccaattg gattcggctt gctacctgaa gatgatgaag gtaatgaatg gtttaaaatg
     5401 acgcttacgg atgataatgg agacgaatta tctgttgaag atacttggtc atatttgagt
     5461 gattatattg tcagcgttga aatcattgaa tttgtagcgg ataaagaaga ataaaaactg
     5521 gaggaataaa ttttacagat aaaggcttag aaggagtcac gacgaataat aaaaaggtag
     5581 tattacctta ggcattgagt aaggaattta tttaggagga aaattagatg gcgcgaccag
     5641 ttttagaggc gatggatatg gatactttga caaaaggaag gtatgtacag ctgttagctc
     5701 gtggttattc acctaaagat gtattcaaat ccctgtctaa aggaacagat atggaaaaag
     5761 aaagattacg aaaagaattc gattattgga gaacccataa tggaatcaag gatttgaaac
     5821 cagcacggcc agtaattaaa cgaaagaaaa agataaccca agactgaagt gtagagcgta
     5881 tgtgatcata ggctttttta tttttgcaaa aaacaagaaa ggtaggaaaa ctcatgaatt
     5941 atgaagaaat cgaaaacaga aaaaaagtgt cgaaagaaat ggaagaaaag ttgctaaaaa
     6001 tgatgaaaca aaaacacctt aaaagattat ctgtcatgca atatatcaat gatatgaaga
     6061 taacaggaaa agagaaagct tgtttgttag gttcaatgaa aaactttgaa cagttgaggc
     6121 gaacttatgt aaaaacaggt tccaattgcc aactattatt agaagtttct tgacgattat
     6181 gatatgaaaa tgatcaatta tgatgtggca ttgttattga ataaaaagaa tagtaaaatt
     6241 taacatggtt tatcttggtt agatgtaggt aaattaattc atatatagaa ggtagataga
     6301 tgaataaaaa caataaaact ttatttaatc cttacgtggg cgtaatcatt gtttttcttc
     6361 tttttagtta ttttgcttat caaggttatc aaaaggacaa aatcgctgaa aaagtagatg
     6421 gtgtaacaaa aacaatccat attcaggaac aggctaaaac ctatcaagat aatttaacca
     6481 gtttaacgga tatttctaag agacaactga ttactaatca aaaacaggca ttagaaaagg
     6541 atctcaaagg tgaaattgct ggaaaacttg ttttttcttc tacaggattt attctccctg
     6601 tttttcaagg agcgaatagc gacacgctta gtttaggagt agcttctact tattatctag
     6661 atactgaaat gggaaatgga aattatattc ttgctggtta taacgtagat acaccaagcg
     6721 ttttattatc cgatatgact gatttatctg aaggagaaga aattgatcta atcgatgctc
     6781 attacaagta tcagtatgaa gtctccaaaa gaggaaaaat ttctgattac agccaggtag
     6841 ttcaatctaa ggaaaacaat tcctttttat ccttgccaaa agcaggtaaa aaaccactac
     6901 tcacactgtt agcctttcaa gcaaataata tgaaaaagtg cgatgtgatc cagtgtgaat
     6961 tagtcaatgt agaaaaaatc aataaataag ggaagtgagt cacattcaag aacttgtaga
     7021 aaaattgatc aataaaatga gtgccatttt tctgttactg ttggtatcca ttctatattt
     7081 aatatggacg gtggggttaa atcctcctac gatattattt atttatgata atgctgcaca
     7141 gttagtgacg tttttcgtag gctgtttgtt tcttttgaat ctgtacaagg taaagagaaa
     7201 cgatctattc ttcattgcag caggcattct tttttacctt ttcttttctt tttttagaag
     7261 ctaccgagga gatactttct atggtgatct gatcgttccg acaattattg ctattatttt
     7321 gattgtaaaa tggacgaaat ttactgtaat tgatcgtagc ttgtatcttg tagtattcta
     7381 tgtcttttta ctcgtaacgg tttatcgagt atttactgag ataccagtac cagaaggaca
     7441 aagtatttgg aatccatcga acaaattatc agatatttgg atcaatacaa atacgatagg
     7501 tagttcttta atgacattag cccttcttat cacaggattt gctagttcat ttggaaaatg
     7561 gtacatgcga ttgctatcat taccagcgtt gattcttgct ggggcaacga tttgggtttg
     7621 ccaatcgaaa gcagcattat atgcgcttgt tatcttcatt atcttagaaa ttttacctaa
     7681 gaaggttttt cgaaatacac acttgtcctt ttggatgtat gcagcagttt cggttctagc
     7741 tttaccgatt tcttattttg ctgcaatgtc agacaaagtt cacttattta caggacgaga
     7801 agaaatttgg cgcaaattct atgaaacatt aggcgaaaaa acaggacaaa tatttgtagg
     7861 gatgaaacct ttctttttcc atagaggaaa tcagattcta ggtaatcata atacgtatca
     7921 cgcactcgtc aatcactatg gattgattgg ttttgttcta tcgattattc ttttgcttag
     7981 tttcttatgg ttgctcgtaa gaaaacgtga gctgacaaat ggacaactaa cattcttgtg
     8041 ggctttttta gcgatcatgt gtcaatcgtt catggaagaa acattaacga caatcagttg
     8101 ggtgccaatt gtattcttaa tgttagcaat ggctacacac caatataaaa ccaccagata
     8161 aatgaaatag aatagtaata agagaaaaca ctttttcgtt gtgaaaaagt gttttttgtt
     8221 ttgtctgaaa ggaggcagat ggatgaaaaa atggttattt ggttttttag gagtcgcttt
     8281 aatcgtcgtt tgcagtgtgt ttggctatgt tagctaccaa aaacatgaag gagaggtgtt
     8341 taagcaaaat atagaaaaaa agatgcccgt agatcaaatc aatgcacacg caaagagtta
     8401 taaggaggat gcaacgaacg tcaataatga tatgtctttg gggcaaatgt tgtccataca
     8461 aaaagaagca atcgaaatgg gcgtcaataa acaagtattt gcacaaattc agattcctgc
     8521 acttggttta gcattgccaa tttttaaagg ggcaaatcaa tacactttga gtcttggagc
     8581 ggctacttat ttttatgaag atgccgaaat gggtaaagga aactatgtcc tagcaggtca
     8641 taacatggaa atgccaggtg ttttattttc tgatattcaa aagttgtcat taggggaggt
     8701 gatggactta gttagtaacg atggcgtcta tcgttacaag gtaacgcgta aatttatcgt
     8761 acctgagtac tttaaattaa tcgatggcgt tcctgaagag aactctttct tgtctttacc
     8821 aaagaaagga gagaaaccct tattaacgtt gtttacttgt gtttatacgt cacaaggaaa
     8881 agaaagatac gtggtacagg gagagctaca ataacaagaa tttaatcaac gcgagtcgtt
     8941 gaaatatgaa atgaggagag taaaaaatgg caataaatcg gtatgtaaaa aaagctggaa
     9001 tgattgttgg aatgttagga atcattgcag gctgctttca ggggtatcga gcttatgcag
     9061 aagatgtcac gcaaaaaacg ccaccagaaa gggtcaatat cacggttcat aaattaatgt
     9121 acgatcaaag tacgcaattg aacgttgata ttgacggaat caaaaatgat ggttatacgc
     9181 acgatcaata tcctacaggt gtaacgaaat acaacaaggc agattatggt gatgttgagt
     9241 ttacgttagg aaatattacg gatcaagtat taccgactga agattctgat ctaaccaacg
     9301 cgaaagtgga cgaaatcgtt aaagatgtag aagacaaggg atctaacagt gagtacgtta
     9361 agaatgcaac caataaaatt acttcagctg tagatgaaaa tggtgagatc acttttgctg
     9421 atcaaccagc ctatgtcaat tccaaaggga atgtatatgt ggtttatgaa agtaaatccg
     9481 ctgctggatt agtcacacaa aaagcaaaac caatggttgt gattgcgcca atgacagaca
     9541 acacaggatc aggattttta aaagatattc atttgtatcc aaagaacatt gtttctaagt
     9601 tgagttttga attaacgaaa tttggtgacg atggcacagc tcaaagcaaa caaacacctt
     9661 taaaaggggc aaaatttgag ttatacaagg gcgaacctgg aaaaggaaca aaattaggag
     9721 agcttgtatc ggatgatcaa ggaaagctga ctgcaactga tttgacgtta ggaaaatact
     9781 actttgtgga agttccttca gaagttgtag ttggatcaga tcaagaacca acagcagacc
     9841 aatatttgtt aggcgcagac gctcgcaacg atgcgcacaa taagttaacc tttgaaatta
     9901 cgaatgacgg cgtgacaagt gatttaaaag cttcctacgt gaactataaa gcaccagtga
     9961 tcgataaaac agtgacaaat ggaacaggag aagaacattc tttccaaatt ggtgacgcag
    10021 tgaattatca aggtacaatt catatcccta cagatatcgc aggtggaaca gatgggatta
    10081 cagtaaatgg tgtaaaaagt gaaacttctc cttacagtgt atttaaatgg ggcgacacag
    10141 caggtaaagg actttcttat gttgctgaaa aagcagatat taaagtaaca aataatgatg
    10201 gttcagtcgt attaaaagaa aatactgact ataaaatcga aaattctgat agtggttttg
    10261 tgatcgattt tatcgtaaat aatggacaag taagtgatac agttgcgaat ttacatggtc
    10321 aagatctaaa aatgacttat aacatgtttg tgaatgatag tgctgaaatc gcaaatccat
    10381 taacaaatag cgtggatttc gtttataaca ataatccatt taatcaggaa gaacaccacg
    10441 aaaaaacgaa agctgacgtt gtgacttatg gcgcaaaatt cttaaaagtc gatagcggcc
    10501 tatttggaac aggtatcaaa gcaacaccgc ttgaaggcgc agaatttgca gctaagaatg
    10561 cagaaggtaa gtactacggt ggacttactg atacagataa agatggtgtc aaagaagcag
    10621 tttgggtaga cgatgtagca aatgcagcaa tcctaaaatc agataaagag ggtcattttg
    10681 aaatcactgg tttaactgaa ggagattact cactggaaga aacaaaagct cctgaaaact
    10741 atcaaaaatt aacaaaagag atctctttca aagtagacaa agattcatac aaagaagaaa
    10801 accgaatcac gatcaaaaat aatcaaaaag cttccgtacc aatgactggt agcaacggtt
    10861 tccaatctta cgtattgatc tcttgcttgt tgcttggggc aggcgcaatt tctgcagttg
    10921 tttactttaa gaagaaagcc tagaaggatc agctaatgat tatcagacac cctaagaaaa
    10981 agcgaatcat gggtaaatgg atcattgctt tctggttact ttcagctgtt ggtgtcttac
    11041 ttttgatgcc tgctgaagcg agcgtggcga aataccaaca aaatcagcag attgccgcaa
    11101 tcgatcgaac aggaacggca gcagaaacgg attcttcttt ggatgttgct aagattgagt
    11161 taggcgatcc tgttggtatt cttacaattc caagtatttc tttaaaacta ccaatttatg
    11221 acggaacttc cgacaaaatt ttagagaatg gtgtagggat tacggaagga actggcgata
    11281 ttacaggagg aaacggtaaa aatcctttaa tcgcagggca cagtggactt tataaagata
    11341 atcttttcga tgatttgcct tcagttaaaa agggagaaaa gttttatatc aaagttgatg
    11401 gtgagcagca cgcttatcaa atcgatcgga ttgaggaagt gcaaaaagac gaactacaaa
    11461 gaaactttgt cacttactta gaaccaaatc ccaatgaaga tcgagtaacg ctaatgacat
    11521 gtacgcctaa ggggatcaac acacaccgtt tcctagtgta tgggaagcga gtaaccttta
    11581 caaaatcaga attaaaagat gaagaaaata agaaacaaaa attatcttgg aaatggcttt
    11641 taggaagtac tgtttttctt tcagtcatga tcattggttc gctatttgtt tataaaaaga
    11701 aaaaataaag gagggtaacc aacatgagaa atagaaaatg gctatttgtt tgtgcagccg
    11761 ctcttttttc tttcactgcc tacacacagt tgacgtttgc agacagacaa gaaagcacgg
    11821 atagcacaga acaaacaatc caaacgtcag atagcagcac gattcaaagc agcgatgaaa
    11881 ccgtcgattc gtcaacagtt gattcttcag aagaacctaa aattgctgaa gacgatcaaa
    11941 tagtcaaaca gaccattcac gttcaaaaaa ttatttcttc cgaacaatta gacaaccagg
    12001 ggcaaaagct tgaaaaacaa gaaggagtaa atggcgcgaa gttttctgtt tatgatgtat
    12061 cggacatttt acaaaagatg gatgttaagg atctcactac tgaccaaatt gaatcccaat
    12121 taaaagatcg agtgaaaaaa ctatccagtg atcaactgaa gctaatttct aatggagaaa
    12181 caaagacaat tgatcaacaa acaggtgtct ttgaattctc ggtagaagta caggcaaatc
    12241 agaaacaagc ttattatatt gtcaatgaat caagtcctga aaacatttct aatagcgagg
    12301 atattttgct attaacacct gtttctgata aaaatggtga attcttaaag gatgtgtgga
    12361 tttatcctaa atcagaagct tcgcaaccta aagaagaagt aaaaaaaatc gtatctactg
    12421 gcgtaaagaa aaacttcttt gagaattgtt gggattttgt tactcacttg ttttctagag
    12481 attaaggaag aaataaaatg aaactgatca aattattatt attcaatttt tcttgtttaa
    12541 ccgcagtctt tttgtactgc ggtttattat tttctaaact atctattttg ccaagctacc
    12601 aactatacct aatgaggatt ttaaacatac cagctgcttc catgccgcta gatattatgg
    12661 aaaagctcat taggaatcca ttatttacta cgatcaattt gatcgttatt gtcggaattt
    12721 cactagtcat ttataaaaaa gaggggatga agggatgaat tttaaacact cgtggacaag
    12781 acggttaaaa tatgtttttc ccataatgat gatgttaggt acattgtttg ggttaaaaac
    12841 agccaatgtc tttgctgaaa aagttattgt cgatccgtca aatccaatcc agaacgtaaa
    12901 gaataatttt attattccaa aagatgttcc taatgcaaaa acaaatatta ctgtaaacgg
    12961 agcgtcaaaa gtttacaaat atcatgttga tgccaacaaa ggtggtttta cagacgacta
    13021 cgtaggatta gtggagggaa acaaaaatat acgctatcct tctttccaaa aagaatacgg
    13081 tgaaacaaac cttgttttag aaggcgtaac aaccaacacc aaagtcaata ttgactatgg
    13141 aaaaatcggt acgtataacg ggaaaaaagt caatatcaag ctagttctat ctaatattca
    13201 cttatactcg gatacgttgc cgtggaatct actagataac aactatacaa aaactcattt
    13261 tcgagacgat ggctataaaa atacgaatgg tgcaatgagt aaatctaaaa aaagaacagt
    13321 actttggatc tcagacaatc ttttctcagg aattgtttac cattcaacac aaatgaatgt
    13381 gcagctagta gccacatatg aggacggtag ccccgttcaa ttttcaggag atacatttat
    13441 cagttttaac tctttgaacc ctgcaggagg aaaaagcacg gatcttaaag gagaatatgc
    13501 ccactatgac aaaatgaata cgacagattg gtatgtcaga aaagatacgg ttctttcaga
    13561 atttaaatct ttctacaaca atctgaacgt ggtaggtggc cacccaggag gaagctctaa
    13621 gctgacacaa gcggataatg atttcaataa tttgcatgat aaattaggag atccgaagtt
    13681 tggtcaaggt actgtgtcct ttaaaatatc tgaagcaaat ccgacgtttg tgattggttc
    13741 ttctaatgtt caaacctggt ttactttatc ttctgcgaca atctttagtg ttgttcctga
    13801 tcaacctgaa aaaacagggg ttgataaaaa tggaaataac gtgaacgata aaatgttgca
    13861 agtaggagac acgattcaat atcgaatcaa acagaaggtg aatcgattag gagtggattt
    13921 actagcggtt tacgatcgat ttgagttaat cgataattta ccaaaagaag taaattacgt
    13981 cgatgcacac gttgaaagtg gtacaaataa aaaattcgat gtatctggtg aagtgaccta
    14041 tgacaaaaca aaacaccagg taaaatatgc agcgaaagct gatacattaa aaaatcgaat
    14101 gaagtataac ggcgaaactt acgaattagt gatcaatgta aaagtcaatg aattggccaa
    14161 tcaaaatagt gtagccaaaa atcagggaac gtcgatcatt aataaagtag aaaaggatac
    14221 aaatatcatt accgtttatt tccctaaaat tccagtgaaa gaagtacaac aaaatggaaa
    14281 agatgtaaac ggacgaaatg acggtaagaa gggtacgccg acagctcctt taaacgcagg
    14341 atctgaagta caatatctag tcacacaaaa atggcacaca aaaggcgtag acgctgcgtc
    14401 agatcactac aaacaattta gtattcaaga tccaattgaa gctcgtttga catataaaga
    14461 aggttctgcg caagtaatag ataagagtaa aggaaaagat attacttctg aaggcacact
    14521 aacctatgat agcaattcaa gaacgctgaa gtgggaagct tccgctgact tcttaaataa
    14581 caatctttta gatggacgag aaattcagct gatatttaca gctaaaactc cattacaatc
    14641 agaaaaaaat attgataacc aagccgtagt agcagtagat aatgtttcta ataaaacaaa
    14701 tgttgtgaca attggggttg atcctaactt gccacaagtt attgttccta aaacaggttc
    14761 tacacattta gtaacgattt tagcggtcag cttactatta cttgtgttag caacttttgg
    14821 ctacgcagtt ctgaagttca attaaacaaa aaaacaaggc tgaaaatcag ccttgttttt
    14881 ctatttgaaa atgggattgg cactaataaa tacgttgtct gaagaaagtg atccgtctgc
    14941 agaaacttca taagcatggg ataaaccaac gatactttga ttgttgtaaa gcaagtttgc
    15001 gttatgagca gcgctatctt tccacataac catagcattt actgctcctg tatctgaaag
    15061 gatctcgtca acgtaaaggt agaaactatt gatattttct cctttagcac cgtagcagcc
    15121 taagctttct aagagatctt ggaaagtacc gccgccaggt cggtaatgac tgaagcttac
    15181 ttgtaattct tttgcacgaa tatctgcagc ttgttgaacg atatcattga attgcattgg
    15241 ggcaacgcca ttttgttgac ggtagctatt taaccaagca agttcttttt gacgcacata
    15301 gttgtttaaa tcacttagtg agatattttt gtatttgaaa gtgatcgttc gattttggtc
    15361 aacattattg attacacgtt gtccattttt atcaacggta acagatgaat cgtcatttct
    15421 acacaagaag tagttttgat cggtcatatt tttccaagaa gtagagaaac tatctccctc
    15481 gtaaaccgtt tgtgtttcag tagataaaac agcgtttgtg tcaacgttta tatggttcac
    15541 agtgacgttg tattgatgag tataggcaaa attgattcct tgattacttg taacgttgtt
    15601 taaagtcaca gtgttgctag agctttctct aggatcaaga acaaaattag tgaacatagg
    15661 tgcttcaatt gtgatgcttt gtccataaac gacgggataa ctcttactgt aattatagag
    15721 ttcttggata tttggatcag tatccgagac tttatttgga cgagctttca cttcaactag
    15781 aaagacttca tcatagtaaa aagtaaatgt ggtatttgtg ttaatcgttt gtgtttgtgt
    15841 ttcattccca tttacttgat actgtggtgc ttcaaagtta gtcaagtcgg ttctagcttt
    15901 tgcagtgtaa cttgtaccag cttttactga gacatgttct tcttttagca gcgttccagt
    15961 ttgtcgattc atatgacgga cagttaccgc atattctgaa ggtttaggtt tgtgttgtaa
    16021 ccctttaaat gcagaatcaa gactattttt agcattattt acttgggttt gagaagcttt
    16081 agaatcgtct agtacttttt tagcattgga taaagcagtc tgaaaattat tccaagatcc
    16141 ttctgtaaaa tctcctttag cagttgattt tacttggttg tacaaggctt gtaattccgt
    16201 tttgttcaca gtaggagctg gttttttctt taatcccttg taagcagaat ctaatgtgtt
    16261 tttggcacta tccacttgtt tttgagtcgc ttttgagtca tttaacactt ttttagcatt
    16321 gtttaaagcg gtttggaatg cgttccaggt attgtcggta tagtcacctt ttttagttcc
    16381 cttaacgctc gtataaagag cttctaaagc tgatttattc actttgggtt tagaggtgtc
    16441 agcaccatac caaccaatac cttcgtattt ccagccatag tctttggtta accattgtac
    16501 ttctttccaa cttgcagtgt agtgatgcga accagaggta acacctggaa ggaaaaggcg
    16561 gtagatcggt ttattatttt tttcggcaga acgccaggca ggcccttcat aagtccaacc
    16621 gtaatttttg gtcaaccatt tcacttcatc ccaactagct gtgtaatggt gatcacgaag
    16681 gcctttattg tataaacgat agacaaggtg gccaccgcta gtcggtgctt cccaagcggg
    16741 gccttcataa ttaccccact taattttcac taggtgatca cgttcttttg tgctagaggt
    16801 gtaaaaatgt tcatggttat ttggattata aaggcgatac atgacgttag ttgaagcagc
    16861 gtcagcagat ccagcaagag caactgtggc agcaaatgtt ccaatagcta taacagtttt
    16921 tgggtttaat aatttcatgt tttcaactcc ctattaaatg attaaatatt ttgtttacat
    16981 tcataatata ccacggtata ccgaggtagt caacggtata ccgtggaaat tttgaaataa
    17041 aaaagccgcc ctatgaagag tgtaaggatg gctgtttata tgctatgaag aaatggattc
    17101 ggcgtatttg gttagtttgg cagcattatc aaatcgcatt ttttcaatcg cacttttttt
    17161 ctttattaaa tccgcaattg ttgattctgc gactgaagaa tgtttgctaa tttcatatgc
    17221 tgtcttgcca gtttcaaata gtaaccattc gattttctct ttatcagcgt acattgcaat
    17281 gctccctctt gattttttct ttattatagc tcttttttgt aataaatcac aatatcaaga
    17341 ggaaaagttt ctatagaaag gtgggaaatt atgagtatcc gttccccgtg tatcaaaatg
    17401 aggtttgttg ctactttcgt tatttaatat actaaaataa aacaacgaaa gaaggaatag
    17461 aatgaaaaag ttaataatgg tatttacttc gttgattgcc atgattgtta ttttaggtgg
    17521 atgtggtagt gaaaaaaata agcaagatag tcaagataat ggcgtgttaa aaccaggaac
    17581 agtgtggaaa gaagaagtag gcggacttgt tcataattta aaaattatag atgatacaac
    17641 atgggaatat tccgaaagtg tttggcatcc tgaacaagta caaataacag ttgagaagct
    17701 aaaagactat aaaggattag aaagatataa ggtaatcgat tcaggtggag tagatttatt
    17761 cataggtaaa acagccttaa tagttcccta taacaaagac ggtttagaaa cgtttaaatt
    17821 tattccaaca aacgaaaaag aacatcgaga taaaagtgaa atattaaaag aatacagtac
    17881 taaatctgga tacaagttac aaaagactag cgagtgattg ctagtctttt tatttatcct
    17941 gaaggaggaa tcgcagtggc aaaagctaaa acgccatttg aaaaagccgc gtctaaaatc
    18001 ttagaacgtc gcggtgtatc tgaaacacag tggaaacaag aagtccttga aaaagcacaa
    18061 tttgacctat tacggggaaa agacaaggac ttagaaggat atatctatca acgtgaacgt
    18121 gaaaagcttg ttttcgatga aattattaaa cactaaaagg agcgaacaat tttatgtttg
    18181 aatcaattac aatgaatttt ttaacacaac cgaaagtagt agctgcggtt gatattttta
    18241 gagcattaca aggtgcagca actagtttaa aaaacaatct gatgattttt gcggctgtag
    18301 ctgccgttgc ctccattgtt cttgggggga ttttcttctt ctttggccga agaggagctg
    18361 aaaacgggaa gatgcacgta ggttatgtat tgatgggggt aggagttata ttagctgccg
    18421 cctctattgt ggtttcgtta tttggaatgt ttggacaaac cccacaggga ctataaaaaa
    18481 taaatagaag gagtaaaaag tacgtggcta ctttttactc cttttttatg aaaggagaat
    18541 actcatgtac tttacgattt caggcaatac caaaaaagat aaagagttaa taaaaaaagc
    18601 aacgaagaaa gtgggaaagc gtactgcctt tttaccgaaa acaattaaat attctgtcat
    18661 tgaaacggaa gaacagctac atgtgttagg acaagtgtta gaacaagaga atcaatcttc
    18721 tgttaaattg actctcacgt tacatgataa agaaggaaaa atagaaaagg ctggcacaga
    18781 atacgttttt ggcccactgg attatcaaat ttcagaaggt ttttatccta cattgatgga
    18841 tttgatccgc cttgatgtgt ttaaggaaac ggatgaaacc atgagtgtgg aagagtctta
    18901 tcgaaacgaa aaactgctac aagttttaga agaagagtta gagagcgacc aaagaaaagt
    18961 gagtcaagtg agtgaagtcg aagtaaatga tgaagtacca tgggaacgac caatctttcc
    19021 aaagaaggag tcaaaagaaa aagagacagt ctatgttgac gaacaagctg atattccgac
    19081 tcagaaatcg atatttgagg aagagaacga tgtaatgggt caattggagg tagatccctt
    19141 tgaagaaaca atggaggatg aagagacggc cgaagtagaa gttgatctag ttgaagctaa
    19201 tgaagagcca acatggactg aaggggattc tcaggaatat attgaaccac ttatcagtga
    19261 agaagtagag aaaaacgaaa cagagataca aaaggcaact gtatttgatt atattttgga
    19321 tcaatatccg ccagagcatg aatggatgaa agaaaaaaat aaattatttt taaatgagct
    19381 ttattcgaaa tatcaattac cccaaaccta tcaagcattt ttagagagta aagaagaatt
    19441 aatctcacag ggtaaaggca cacttttaga acagttagag tctgttcaat caacaaattg
    19501 gcatgagctt gcacaagaag atttattagc cacttttgaa gaacgtcaac aagaaacaga
    19561 tcaagaaata aatgagtatg cgacggaaca gtcatctaat tgggagagaa caaaagagga
    19621 actaaataaa gaagaacaac gagtgattga agaagaagta caaaaaatta aagagcgata
    19681 cgaaaagaaa cgcgacaatg cgtattcctt gtgtatagag aaaattaata actttactaa
    19741 aactaatcaa gaagctttat cgaaagaaaa agaaaacttg ttaaaagaac gtataaaaga
    19801 acgaaaagaa gagttctacc gaggtttacg tacagataag ctaaagatta gcaaagaatt
    19861 aaatgaacaa ctgaataaac tttatcaaac aacgactgaa gttcttatgg aaagacacgg
    19921 gcagatccag caagaattac aagcacaaat tccaaaatgg aaaaaagagt atgaaattca
    19981 acaacaagaa ttgaaagaac aagaagaaaa acaacgacaa gaagaaaaag agcgcgaaca
    20041 attagaacta aaaaaacgtg agcagcatct tgcagaacaa aaagtggcga tagaaaaaca
    20101 acggttagag caagaaaagg aaaaagaagc agctgctcgt aaggaacgtc aagaacaaat
    20161 ggatacattg cgacaagcac agttgaatta tctagcacaa cctcaaccag tagctgctgt
    20221 tcaaacgcca gtgaacaacc aagcaaattt aactccttca ccacagcgtt cctttaacgg
    20281 atggatggtg ggatgtattg caagtttaag cttgcttcta ggtggaggaa cagtatttgc
    20341 ttttaatcat atcaatcaat cttcacaggc agattctgta gccacaacgg cgtcaatcaa
    20401 ggaagaagcc caggaacaag caagaaaaga gtatgaacaa caattggaag aattattgaa
    20461 tcgtaccaat cagtcaacag cagagtcaag tatggaaaat agcaaagaga gtgatcctag
    20521 taaggctaaa gaaggatcaa gcgattcaac tgtacactca aacacttccg aaagttcaga
    20581 atcaaatgag gtgaaataat gcgtattaga gaaacaacga gacgaaaaga caaacgattc
    20641 aatttagaaa agaataggta tctttctcat ttctatcgct atactccttc aggagaagag
    20701 ctaccagaaa aacatgacaa acgtatttct caaaagattt tttatagtgg cttagcttat
    20761 cttcctttaa actatgttgt tacaagaata ccagaagcat ttcatcgatt tgagattatt
    20821 ccaggaagtt tacaaggagt gaatattttt cagttacaag aaatgccgca gttattccat
    20881 tttgattcaa ctggtttttg gaatcctttg accccaacaa caagtttagg cacacgttta
    20941 gttgtttcta cgatttgtgt tgttccagct gtacttatgg gattgaaaat ggacatgtgg
    21001 tttcgtccgc tagcagatgg gcaaaaagga gataaccgat taaaaacgtt aaaggaaatc
    21061 caacaaattt atccgcaaat accagaatca aagggaagtt ttcctggtta tggcggaata
    21121 ccaattactc attataaaaa atactggtat attcagacgg atacagtaaa tacttgtatt
    21181 gttggtactt cccgctcagg gaaaggccag atagaagttt tagcaaccat tgacaatttg
    21241 tcgcgtgcag aaagacaaag ttcaatggtt gttaatgatc caaaaacaga attatatgtt
    21301 gctagtaaag atgaactaga agctagaggg tatgatgtgt atgcctttaa tatcaccgat
    21361 ccactgcaat caatgagtga taatccattg gcactcattg tgaaatactg gaagcgagga
    21421 gacatagaca ccgcaacaca gttaaccaat acttttacga atacgattta ttatgatgca
    21481 aatgcttcag acaataaata ctttaacgaa aatgcgcaga aagctgtcaa tgcgcttatt
    21541 tttgcgttat tggaacaagc ggatcaaaca ggggattact ccaaattaac accaaataat
    21601 ctcgttgaac tactttcaga aattggcggt tttaattatt atccagatcc tgagaatgaa
    21661 ttcaagcagc tcaatgcctt agatgagttc atgaatcagt taccccctgg aaatatagca
    21721 aaaaaacaat atggggcaac aaaaattgga tctgataaag cgaaagggaa tatcttgtct
    21781 acggcaatta caggattgaa tccatttacc ctaacgaaaa ttgcgaagat gacttctcaa
    21841 tcgaccattg attacaagtc cattggtttt ccgaagtatt tggatctcaa attacatgaa
    21901 agcctattaa atcaacgcat tgtcgtggaa ttttatcata agggaaagaa atttcacgag
    21961 gaacgagtca aagttggcta tcgtggtttt tgtgaaatca actttgattg tcatttagag
    22021 cagggagatc atgtttgctt aaaatacaat catcaaggaa aacaatatgt tgcttggtat
    22081 gagttttctc aaaaagtatt gaaagacgaa gagggaaaaa tcgtttatcg aaaaaaacga
    22141 ggagaaactc atttgccaga actagaaaaa gaagccgttc taacattaga tgagaagaaa
    22201 agtaacctat tagtagagtc tattcggatg cactataccg ataaaccaat ggctattttt
    22261 atgttaacgc ctgattatga tccatctaac catatcattg ttagcatctt tcttagtcag
    22321 ttgtataaag aattatctac gcaatgtgtt aagactaaag gagataaatg tcaccgtagg
    22381 attcatttta ttttagatga atttggaaat atgccaccga tggacaacat ggaaggaatc
    22441 atgacggtta cggcaggtcg taatatgtta tgggatctgt ttattcaatc ttatcagcaa
    22501 ctttatgcga agtatggaga acaaaacgca gcgattatca aagaaaattg tcagacacat
    22561 atttatatta tgtcgacaga tgataatacc atcgaagaat tttctaaaaa agtggggaat
    22621 aagacggttg aacaagagaa cagtaccatc aattcattag gtatgaatac tcatatcaat
    22681 cgcaatgttg attcagatcg tatcttaact cctgaaagaa tttctacttt tttagaaggt
    22741 gaaacgattg tactcgctcc tttaaaacga caagatttga aaggtcataa aatacggccg
    22801 tatcctattt ttaatcatgg ggaaacgaat cttccttatg cttatcaata tattgaagat
    22861 ttcaatccat cgtgggatat caatgatata gacatacatt gtacacatgc ggacttggat
    22921 cttaaggctt tacaaattga ttatgattat ttcctaccag atgaatatgc tagaaatctc
    22981 tatcatggac tgcatgatca attagaagaa aaaaacgaag aaaatatgtt ttataaaatc
    23041 gttcaatctt ttgagaatga gacggctaaa aaattgttaa ttcaatttta cgaagaacaa
    23101 gcaacggatc gtcttcaaga atatgttgaa aagttgatca aaaatgaaga aatttctgaa
    23161 atgattagga aacggctgtt attggaagct gaaaaggcgg tgaaagaatg atcattggag
    23221 gaattttctc tggcatagcc gactggtggt caggtttatt cggagaaggg gatgcagatc
    23281 ccaaaaccgt aacgaaagtc ttacaagatt atggtaatta tctgcagtat caagatgtat
    23341 tcagttggat ttgtaatact tttttatggg gattgatcaa agggttatat aatctcaata
    23401 ctttattaga aaaaacaatt tatcaaagct ttgatttaaa agacttattg aacgccgctg
    23461 gtgttaatga actatttcaa agtttgatta gtaaggtatt ggctcttttt tgtgtcgtca
    23521 cattaattta tttaggcttg aaatttttta tgagtaaaca cccaccgaaa gtcaaaaata
    23581 tcttggttaa tttatttatg gccatgatct tgatttttgg tggtagttct ttaatcgatg
    23641 aagggttaaa tatcagtaaa aacttttatg gagacgtcac tgcagcaaat aaagcagata
    23701 aaacgggttc acctgctttt caaattattc aaaataatgt gattgatgtc agtacattac
    23761 tagcgactga cccgaataaa gtagaatcct taccaacaga taaaagaaat gctttaacag
    23821 cgaaaaattt caaaacagcg aatatcaatg ggattattac acctgatcaa gctaagaaaa
    23881 tgtctgaatc aagtgatatt agtacagtac aaaaagatcg gttaaaggca ttacagtatc
    23941 gactagagtt agacgataat gggaaagaaa tccctgttca aattagtgat gaaggtttag
    24001 caaaatatgt gtatacgtca ggctatcgtc gatacattag tagtccaggg attattttgg
    24061 ctggggaatc ttctttgtcg gtagcctatt tatttatttt gtttacaatc gttacttgca
    24121 ttattgagct agtatttaaa aaattctatt tagtaattgc cgcgtcaacg gactttgaga
    24181 caggacaacg gatgaaaagt gcgatagaag atatttctca atccttcttg ttattggcgt
    24241 ttacgatttt agaattacga atctatacat taatgctttc aggtatcggt gatttgcatg
    24301 cggtaggaaa gatcaatgga ttcttgtatg ttgttgcttt aattgtgcta actattgcgc
    24361 tattcaaagg ctctcaatcg gttacgaaga ttttcggtgt tgatacgagt ctgaaaaacg
    24421 gcagcaattc tcttcttagc atgtttgcct taggaaatat tgcgaaaaat gtgggtagcg
    24481 gagctaaaaa ccttgcaagt gctggtaaga gtggtttaag ccatttaaat gatattcgta
    24541 agaatggatt tggccatcga aaagatatta cccatgataa cggggaagaa caatcagacg
    24601 ataaagctac aactgtacct aatagtaaga agacagtttc cgaaatgttc gggaaagcga
    24661 aaaatggtgt ttctaaagcc gcagaaggtc ttggttacgt caatgaacgt gggttaaaag
    24721 gaacagttga agatcttaca gaaaaagcca aagacacctt agaagagaaa ttagacggca
    24781 cgagagctaa agaatttgct gaagctgtga agaatccatc cgaagcacta gaaaaacaaa
    24841 aagaaaaagc ttcagcagtc aaagaaggac taaaagatgc gtatggtgaa ggacaagtca
    24901 atgcagcagt gaaggcaaat acaacaagtg aaaaagaaaa tcaagaaggt gcagcgattc
    24961 cttcagccaa agatcaccaa gatgagttac attctaacga aaattcgatc ggagaaaaag
    25021 attcagaaga aggacaacat ggtcagttac caaaaaccga tccagaacaa tatcgttata
    25081 aatctaacat taattctgaa aacgaaaaac gcatttcaga tttaccaaaa cgaaatcaag
    25141 aagtacaaac ggatgaggat tccatcgatc tgccaaatga taatggcatc gaagttggaa
    25201 ctgaaaaatc aacgaaaatt ggtttgccta agacacaaaa tttaccaatg aaagatagtc
    25261 gtttgaatca attcaaagag aatgatcaaa gctttgttca tcaatcacct gcaggtactg
    25321 ttcaaatgaa atcaagtcgt ttgcctgaaa atggaaatct gacaactgtt tcttacaatt
    25381 tagctgaaag tggtgaaaca gagaatgcgt ccgttcaaaa tattgtgaca aaagaagctg
    25441 cacctaagcc aatcaataaa gttcataatg gatacagacc agcaaacgta gcatttactg
    25501 caccgacaaa aataaatgtg acaagagaaa ctaaaaacag gaacaatgaa ttgaaagaac
    25561 aactattgaa ggatatcaaa ccataaaagg cctatttaag ggcctttttc tttataaaac
    25621 aagtttaaaa tggaaaggag aaaattgtgg aggatatttt aatagctacg tttataactg
    25681 cactgggagc atttttaacg atatttgtgg tgactattaa aggatttaaa gatacggata
    25741 gtttacaaaa agatcatcag tctattttag atggtcaaaa aacacatacc gaaagcatta
    25801 ttgtacacct ttcagaagga ttcacttatt tgaaagatgc tatgcccaca ttcacagtaa
    25861 aattaacgga aatatttcat tctgttgagc aaatatcgtc agaattgaaa gagcaaagac
    25921 aacaaaaaga tcgtcaactt ggctcactta attttaggca agaaacgata caagaatcat
    25981 tggagaatgt aaatcgatta aacgatgaaa tgcaacgagt tcatttggaa aatgaagaat
    26041 tacgcgcaca aaattatgat ttaattcaaa agaaaagaaa tctggaacaa aaaattgttg
    26101 aattaaaaga agaaaatcgt caattgaatt atcaattacg acgaggaaaa aatcgttctc
    26161 gtgatttagg aaatgaatta gagttgtaat atttagaaaa acgctgtgag aaatcacagt
    26221 gttttttatt tctaaaaata caaaatataa ggggtatggt tatattatgg ataaatacat
    26281 tcatatgaaa aatcctccaa gatttagtgg ggaatggaag tttttcgcct ttttcttttt
    26341 agatctatta acgcttggtg gctgcttttt ttgggcgaaa atagtcaata atcttgtcca
    26401 cttaccactc ttttttgcac tcttgaatta tggattatgg cttgcgatag cgttagtgat
    26461 tgtttggcga ccctataata accctggtca acgccaaatt tttgcgatta tcgaatctat
    26521 tttctttacg gataagaacc actatcatgc gttagatcct aaccgaaatt atcatggtac
    26581 gtataaggag gatgaataaa tgcgagtcaa aggacaaaat tcagttgata agaaatccat
    26641 tttgcagttt ggaaaaccag aagagcgctc tatcttggac ttatttccat ataaatcctg
    26701 tacagaagag ggagtcttaa ttactagaga agatcatttt cagcgttatt atcgtgtcgt
    26761 ttccactgac gtggagggat taaatgaaca agagaaacta gaacgaatga atcagttgac
    26821 caccgtcatg cgtacgtatg tgccaacaat taagttagtt agtttgacca cagagacgga
    26881 tctaacggaa caaatcgtgc aaaagcggca gttattagat aaaaatcgta tggaacagtc
    26941 actaggaaga aatctacagc gattaagaaa atatgaaaag aaattagtag aggagatcca
    27001 ggaattaaaa cgggcagaac aagaacgtcc tgacttaagc ttctttttcg ttattgaagg
    27061 aaagacaatc aaggatttac aaactagaaa tcgtcagtta atgcgatcta gtggcatttt
    27121 agggttaaaa ccactctaca aaaaagaatt gattaagatt ctttatcgaa tgaacaacat
    27181 gaatgacgaa taaaaaagat ggaggaaatg attcatgcta gatgtgataa aaacagcttt
    27241 ttcaacgcaa agtaatcaaa aggtgattga tccattaaaa caacttggta atcgtgaaat
    27301 agagatttta aaatcaaaag gttatgattt agatttctta aaacaagtga tgccacaagg
    27361 tgggttgaat tttgatgaag aatatgtgac ctatggaaat ggttattcac gatgtgtgac
    27421 agtttatcat tacacaaaaa atcctactct tttttggttg gccaatctca tgaacaatcc
    27481 tcatacagtg gccacactag atgttagcac agatgaaaag caaaaagtga ttgatcaaat
    27541 caaccgcgca ttagatgaat taaatgatcg atcagataat gaacgaaaag cgactgaccg
    27601 aaataaaagt gcggaagaat acctggaact agcggaatat gcccgaaaat tgacttctaa
    27661 tggggaaatt tctaaacaag tcaaagtgag agtacatgtt tacggaaata cgatccaaga
    27721 agtggatgaa cgggcgcagg aactgatcga aaatctaaaa gggatggatt atcgtgcggt
    27781 gacttatctg cataaaacca aacgagattg gcaatcgatg tttaccatgt tcgatgaaca
    27841 agctgaatgg tttggaaata tcaaagggca atcacttcca tcgttaaaca ttggcggagg
    27901 attcccgttc caccaccaaa cgctaaaaga tccaggaggc acacaatatg gggaaaccat
    27961 gacaggcggc ccatttgtct ggaatgccac gtataaaaat agtgtacgtt tatctaccaa
    28021 taccttgctt ctaggaatga tgggagctgg taaatcgacc gttcttaaaa tgatcgcgga
    28081 agcccattta gctgcaggag actttatttg gggctttgaa aagggaaaag actttattcc
    28141 tttcttaaag gaatataacg gtattatggt gcgtttagac ggatctgacg ggatgatcaa
    28201 tcctttagag atctttgcca cacggacgta tgatgaagca tccagtttat atgacgatgg
    28261 ttcagtcaaa gatttgaaga tcaatgaagc agcgtcctat caaacgcact tagacaaagt
    28321 agtctatcag gtacagttag tgagtcctca gctaaaagga acgatgaaag cagaattcaa
    28381 gacctacttg aatcgttttt atgaagagta tggaacagta ccacgcggtt ttacttcctc
    28441 aaattcgcgt tcaaatactg atacgcaagt cacagggaaa gatccagaag cttatccgac
    28501 gttcaaagaa tttttagcct ttttaggaca actggaacta ccaggggctt cccaagagaa
    28561 aaagaatcgg aaagaagaaa tggagtctat cgtggaatcc ttatgtgaga cttatggcat
    28621 gatttttgat ggtcatagta cgattcgaca ccttgaccaa caacagttgg tcttttttga
    28681 cattgactct attacaggcc tagatcgagg ggtacaacaa tgtcagatgt acatggccat
    28741 gacgttgatt tggaatcagg cattgattca aggacgaaga caacgacgct taattaaaga
    28801 aaaacaaatg gaagaacaag acttcaaacg cttcttggcg atgattgatg agtgccataa
    28861 tgcgattaat ccagatttca ttgaaacggt aaattatgtc acaaacttcc aacgagaaat
    28921 gcgtaaagta gaagcaatga ctgttttagc tacacaatcc ccacaagaaa tggtgccaga
    28981 aaatatgtct tctgataact tctcgaaact gaagaaagtc tttgaatttt cttctacgaa
    29041 gatctttatg cgtatggatg aatctatttt acgtcatata gaaggattag ttggtaaatc
    29101 aatgacgaac tcagaattag aatccattcc tcaacaaaat caaggagacg ctgtgatcaa
    29161 ttttggctca aaagaaacca ttcgtgttca ttttagtccg aacaaacgtc aattaaaatt
    29221 gtttgatgga ggaaaataat ggaaaaccaa aatgaaagtt taatcaaaca gtatgttaag
    29281 cgtcgtgcaa agcggcgctt atttttgtgg gtgtttggta cttctgcagg tttgattact
    29341 atattgatca ctgtgtttgt gacccttttt ctaatacttg cggcaggttc tattgataat
    29401 tctgattcaa gtagtggtgg cgaagctttt acaggagaat attcggaagg cttacccatt
    29461 tataaagaaa tcaaaggaag aggccctttt tctgatgaga ttgcgcaata tgctgtaggt
    29521 gcagcagtga agtataaatt attaccaagt gtgatccttt cgcaatacgg ttatgaatca
    29581 gcgtttggta cgtcggcgtc cgcaagaaat gatctcaatt attttgggat tacgtggttt
    29641 gatgggtgtc tgtttcctaa aggaactgcg cgtggaattg gtggcattga aggtggctgg
    29701 tacatgaagt ttcccaactc aaaagctgcc ttctcctatt acggctttat ggtagccaca
    29761 caatcaaatt ttaatgcttg tgtcggaaat aaaagccctg gcgcaagctt attgatctta
    29821 ggacgaggag ggtatgccgc cgcaggaatt actgaagaca gtgcctatta taaaaattgt
    29881 atgtctatta ttaatacaaa taaattgatg gagtacgatg agtttgcgat taaacactgg
    29941 agagaaggcg gcggaactgg tggtacgatt acaggaagct ggggcaatcc attcccagga
    30001 agtagcttag ataaaaattc gttcagtgga ggacaacttt ttgggaaaaa tccaggagga
    30061 gaattccgac ctaacgggtt ccatgatgga ctagactttg gttcagtcga tcatccagga
    30121 agtgagattc atgcggttca tggcggaaaa gtcgtgtacg ttggcaatcc tggtatttca
    30181 ggtttgggtg cgtgtgtgat cgtgattaat tacgatggct tgaatatggt gtatcaagaa
    30241 tttgcaaata gtacaggaaa ttctcgagtg aaagtaggcg atcaagtgaa agttggtcaa
    30301 gtaattggga tacgagatac agcacacttg catttaggat ttactcgaat ggattggcgt
    30361 caagcacaag gacatgcatt cattgatgat ggtacatgga tcgatccgtt accatttttg
    30421 aatagcagca aaaaatagat caggagaaaa aatatggaaa ataaaacctt aaaaatcgtc
    30481 ttaacagctg caattagcgt tagtttaatc ggcaatattg cgttgttttg gcagcttaaa
    30541 gaagaacaag agacaaatac ctataaaatt gaagaagtgg ctaaaaacgc gtctgataag
    30601 ctcaaaaaaa attcttctga agcacaggcg aagattgaca agttaaatca aaccatcaat
    30661 gagaaaaacc aagaaatcga tcagctgaag caacaagatg gcacaaaagc aaaagaggaa
    30721 gtaactgaag cacaaagaaa gacggcagaa gagttcggtc aattggccat tgataaatca
    30781 ttaagcagaa atgaattaac ggaaaaacta aaagatgtcg caacccaaga agtgatcgac
    30841 aaattaagtc ctgtagacga tgatcaccaa catgatgatt acggaagtta ctcttttaca
    30901 ttaggtgacg tgcaaactta cgctcaaaca agcagtgtaa aagaggaaca aaattttgtc
    30961 gtatttgttg attatacaat cggcaatcct caattcaaag atgtcaaacc acaaaaaata
    31021 aaaggtggat taactgtcac tgaaaaacaa gtagatggtc aatggaaagt cacagacttt
    31081 agttatttca ctcgttagga ggaagaaaat gagtaagaaa aaaggagcaa gacaacgttt
    31141 taaaaaacga aaaagttatc ttagatggct ggggatcttt atgattctcg gctttttgat
    31201 tcttgctagt ccgatttaca cacataaaaa ggtagacata ccagatgaag taagcacgaa
    31261 cgcattttta aacacgaagg aactgacgat ggtttcaaaa gaaaaaggag cgaaccagca
    31321 attagttttt gaatttgcga tcgacgatga agatcagagc ttattaaaag aactagctaa
    31381 tcttaattat cgtgtagaag taaagacagc taaaggggat tatcaagcaa taaaagccaa
    31441 agtgatcaag gtgtctgatg attattttgt agtgaagtta gcacatgtac cagaagaata
    31501 tattgctatg cgattaacta ttattcctga aaaaattgat ccaaaggtgg atatgcaaga
    31561 accgcaagat ctgatttttt atattcacga agataaggtc aaagatcacg tgaaagacga
    31621 agattatgaa caacatgcga tcaattacaa agtgaaagga tacaagaaag aacaaaaagc
    31681 agcacaaaaa caaattgaat ccttccaagc aaccattgat ttgaatgaag aattagtgaa
    31741 gaaactaaaa gatcaattgc cttatcaagt cgcagaagat caggaaaata ctgaaaataa
    31801 gattaatagt taccagcaag aaattgaaac atcgaaaacg caaatgaaag atcaagaaga
    31861 gagcattcaa aaacttcaag aaaaaattga tcgtatgaca aaagaaaata tttagaagaa
    31921 taggtggagt aaaagaaatg aagcgagcga acttggtcgg caaagatact ttcgctgagc
    31981 agaaagtatt gattaaagcc tatctcaaag ttgtaaaagc taaagaaata tgtcaagaag
    32041 tgaattatct aacacaacaa tatctgagtt gaagaatggt agaaagagtt tagatacctt
    32101 aaaattcaga tcatttgaag ctctatatat agctgctaaa aaatatttta cagctgataa
    32161 taaataaaaa attaaggtgg gttctatgtg aaaaaaacgt atcaaaagtt tttatggatt
    32221 agctatatcg tcctatttat cgttgggttt ctcgtcagtg tgtccgtgat cgtcggaacg
    32281 ctttttcttt tgttctctga cgaagatctg gtacttaagg ggttaatgag tacgttatcg
    32341 tgtgtcatgt tactttattt atgtatacag atcaacgaaa ttatgccccc tcattggcaa
    32401 gaaaagaaga aagaatttaa ggaagaaatc gaaataaaat ccaatgactg gattgaatac
    32461 acatggcttc ctctgaaaag aaatagcaaa cgaaaggaat tttgggcatt gcaattatgg
    32521 ccaataggaa aactttttat ttatatggct tcacttatgg ttactttaat cggttatttg
    32581 gtggtggtct atggggtggc ctattacttg ttaagtgagc caaaacagat cgcggcgtca
    32641 aatattttca cggcagtaat gacattaatg tgtgtcatgt gcttttctat ttttagttac
    32701 ttactcgtcc aatttatcag gcaaaattta acaatgagta aacttttcaa aagtttattg
    32761 gacttactta tcttaggcag tatgttaacg actctaacag atcggttcga acaatctgaa
    32821 aaaacggtag aggggataaa gaacttctta acgacgattg atcaatttat aaatggatat
    32881 atgtatttgt ttgaagtagg ctttattctc actttgtttg gttgtgtatt tataaaactc
    32941 attaaaagat caatcgaaaa agaaatggtt attgatctaa ttccgacgct gagcggctat
    33001 gagtattacg ttgattttgg aaagtatgag gagttgatcc atacggatat cgttcacacg
    33061 agtatccatg aagtaaccgt taagggcatc agatctactt taaaagatgg acaggagacg
    33121 aaaacaatcg accgaagaaa agaggtctac aatttttata aagttgaagc aagtctacga
    33181 tatggcattg ggaaattgag gttagatggg agtaatattc aacaaaacaa accatatgtt
    33241 ttaggaaaag tggtgattta gaacttccta tgaaagatga ataaataagg agaatctttt
    33301 gaaaatgatt cttctttaca gaattgtgct tatagttggc acggagttaa aaatcttaaa
    33361 gaaggagcag ttattcaaag tgaaagaaca tcataatcag ttactatgta ttaaaacggg
    33421 tacgatgaac attcaatacc gaacagaata tttagaatta acgaatcaaa ctgatttttt
    33481 gtcgattcga gagcaacata agcaagaaaa attaatggct acttatagcc aattgattga
    33541 tgagtgggaa caattcaagg aatctaaaac ataaaattcc atttaaacac cttatttttt
    33601 aaagagcata aggaaacgtg tacccacttt caaaataaag tgggtagata ggctgtgcct
    33661 atcacgtttc tgaaaaaaat aaatgacccc aaaattttca atttatgtgt aggtttatgg
    33721 gtagcaaaaa tatgaatgtg ggcagcaaaa agttcatttg tgggtagtaa aattcaaatg
    33781 tgtgtagcaa tgtgtgtagc tacacacatt gctacacacg ctataacata tagtgaaaag
    33841 gagatattta tggaagtaaa aataagagat attgatgaaa aaacgattca aagaattgac
    33901 cgaagatgta ttgaattaag tgaacgcacc gggactaaat ggagccgaaa tcgataccta
    33961 aaagttttga ttgaaaatga ttttgaccat gaacttatgg atcatagaaa agatcaattt
    34021 gatcggttgt tagaaaaatt tgtggatatt caaacttata atacgaaaat tttagaagaa
    34081 tatattgcaa caaataatca attaatcgcc ttgttaattg aataataaaa atagtattgt
    34141 gaatttataa aaggaggaaa tcaattttgg caaaagcaac aagaaaacat gtatatcttt
    34201 acgatatgca tatcgaagta cttgatgaaa taatttctac tcatgaagat atatctaatt
    34261 atagtgaagc agtcagacat ttgtgtatga tgtatgatcc aaaaatcgaa gaaaaaataa
    34321 atccaattca aattaaattg aatgcaatgg gaaaagaaat ttctatatta accgaaatgg
    34381 tttcagagtt tgcggatctt catttgaaag atacaggaat actaattggt acaaattcaa
    34441 ctgtctatca agaagcaaaa gagcgtgtgg aagggaaaat aaaagcgaat caaacgaaaa
    34501 agtattctcc taagatcaag aaaccaataa atgaatctgt tcatgccaga gtagacccgt
    34561 ttgatccaac aaagttttta aaaagataaa aagtagaagg ggaacatgat gaataaatcg
    34621 cctgcagtca ttctcacttg tcaatttacc ttgcccaata aaaaatcttt ttcaacatac
    34681 attgattata tgacaagaga aaaagcgctg gaagaaaagg aacgacgcac gccggacgaa
    34741 gaacaggaac tgcaacgaat caagaatgct ttagaggatt tttatattcc tgaaggagaa
    34801 actttttcgg agagtaagac agataaagaa ttcagtgaaa cgtcgaatga agctcaatcg
    34861 ttgatggaac atggaatcaa ttttgacaag ttagaggaac aagattttac caaatatctt
    34921 tcttatatga cccgtcacta tgcgttagaa caaaagaaag aactgacgca aagggaacaa
    34981 aaagaatacc aacggttgaa ccaagcaatg aaaaaatatc aaacagagcc acataaaaaa
    35041 gcttcaggaa atcttcctgg agttttttct atggcttcag acgaagtgaa aggaagtgat
    35101 ctgaaggaga tcaaacaaat cttccaaaga gggcaacaaa aaggctcaat catttatcaa
    35161 gatgttgtct ctcacgacaa ttcgtatctt gaaaaaatgg gcttgtacga tcccaaaaca
    35221 gataccttag atgaagaagg attaaaagca gctggaagaa aaatgatgga gacattattc
    35281 gagaaagaac aattgaatga aacaggttac tggatggcaa cgattcaccg taacactaag
    35341 catatccata ttcattttgc agttgttgaa aaagaaaata cgcgtaaacc ttacacggag
    35401 gttgaaaatg gtgtgagtta tatcgtaccg aaaggtaaga gaagacaagc aacattagac
    35461 gcaatgaaga ccaattatgt acatgagtta gaacgttttt cttatgaaaa ggatcgaatg
    35521 attggtatgg agaaacgaaa tttattgacg cggaaaagtg atttgcgtaa caccttaaca
    35581 aaagtggtaa aagagccagc gcgttacgat cgacacgcaa tgaacttatt aaatgaagta
    35641 tataaaaccc tacctgacaa acgttcggaa tggcattatg gggatgaaaa acgaaccaaa
    35701 ctttcaccat acacaagaga gaaactcgat gagttaacca aatatgtgtt aacaaaagaa
    35761 cctgaatatc aagaatatat acagatttca aaatcattga aagaagaagc aaaaagtctt
    35821 tatggggaaa gcaagagaga atcaaaggat gcagaaaaaa atgctctctt tgatttgaag
    35881 aagcgcacag gaaatgccat tctaacagaa ctgaagaaac aggatagtca aataaaacct
    35941 ttaatagaaa gtatggatca gatgcaatct atttacaatg aacgatcctt tcgaacgctt
    36001 aaacagttac caacgaatga atacaaatat agttacgaag aattcatgaa gcgcaggaaa
    36061 caattccaac aaagagttgt cacgcaacgg agtttgcgtc aattaaatcg aacgattaat
    36121 gcccatgaag aaaaatacca cgcaagtaaa gcctacgaag agcaacaacg aagaattcaa
    36181 atggaacaag aaagacagta aagacagtag gaggaatagc aatgaaacaa tatttagatc
    36241 aatggaaagt tatagaagga tcattaagag aagaacgaat cgaacaactt cccgattgtt
    36301 tagaaaaaga gcatttgttt cagataagag aaatgttgag aaacgaacag tttgatccaa
    36361 atcaattttt agtcgttgag tactcagcta ctggtgtgta ctgttgtaat catgtgaagg
    36421 gtgaaaaata ttttatcatt caagaatatg agggcaagtt agcgccttat tatactactt
    36481 gggaaatgaa tgaagagggg atcaataact tcccgtgtaa aagcattgaa gagtctattt
    36541 cactcacaga atgttagttg ttaagtgaat aaaagaagta aaagagtcct gaacgtaatt
    36601 gtccaggact ctttttttca atgaattgtt ttccgccaat tcaatgagtg gtgcgatttg
    36661 cgactacatt atatcaaaag aaagagaagg gaggaagaag aaatggctta ttcaacgatt
    36721 ggagttgttg ttgaaaaaag cagagacaat ctcgtttttg tgacagaaat tcaaacgggc
    36781 agagcttttg tcgtcacaga caaagcggca aaagcgtatc aaagtggcga tattttaacg
    36841 ttaaatctga ctacgaagac gttcgtcgat gcggcagaag attatcc
//
LOCUS       DAFEKH010000026        36853 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.027, whole genome shotgun sequence.
ACCESSION   DAFEKH010000026
VERSION     DAFEKH010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36853
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.027"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(324..893)
                     /locus_tag="LP386_001456"
     CDS             complement(324..893)
                     /locus_tag="LP386_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBL1918696.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(967..2256)
                     /locus_tag="LP386_001457"
     CDS             complement(967..2256)
                     /locus_tag="LP386_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918697.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESENKSKLTKVLYQEWLRYVI
                     GIHDRLIEEVRYYQETLEKFPNSKDKLYQFRLAIQQAFAHPAVEWGMLLLKTLQERGY
                     LDVHPPEVKIVFFFRYEHQEARRLAGVLNKTLRHRKRISIHVCTRNKPPRYADLVITD
                     HFFPLDHNEDQKTYLYHPSFGIERLLTDINYWLGKNR"
     gene            2610..3458
                     /locus_tag="LP386_001458"
     CDS             2610..3458
                     /locus_tag="LP386_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HBL1918698.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPVPVR"
     gene            3472..4545
                     /locus_tag="LP386_001459"
     CDS             3472..4545
                     /locus_tag="LP386_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HBL1918699.1"
                     /translation="MEKIKDYFINFVLFLVYFIIVLFALVFNNSLGWFLLAFFTLYVS
                     WSLISLSSFLKKLSVTCTLQPLVYRKKSMQVIFSIAKKRTFSLPLPRLQIGFPAIFAE
                     KKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFRKSAKREISFPVTVL
                     PAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNRIDWKLSAHTQEWLY
                     REYDYQEEECSPLFCFWGSHSPKFEPLLDLYFSLWHLRKEKQPELLILGNRAFHGKDP
                     GHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIETLSKDRTVYLVYFV
                     EKQLMVQEKDKICSLPGGEWIDD"
     gene            4535..6706
                     /locus_tag="LP386_001460"
     CDS             4535..6706
                     /locus_tag="LP386_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HBL1918700.1"
                     /translation="MTIKWEKWLCGVYSFVILSVGAPIFVVANQLQNSYLLILTIGVL
                     CLIVCCIPKKWVRLLLSLPVMIGCLFLYFPSKTFSLLWILQFFSSVTEEFFHLSQGKL
                     YYLPEKTAFFLIMLLIYLFITLTVDYDYLYAPFLSLMAYFMMLTVFREKDLLYEMIAV
                     VTVLFVYLAARQFFSMRLLSGNTRFQSLTTVLLICFLTISAILPLYLPKVHQSLEETS
                     EPIREYLNDEGLYDTLHEYQLTGSARTGFSENDEQLGGPLYDNGEVVFTANQKGNGYW
                     KIENKNHYTGSGWIEDQDAPIQPIQEFPVDITSYQTVMEDKENITLTLKKQAFLPYPY
                     GNTTLTDFSLASGQTLYYLPESQRFIPVPNESTRSATLQTERLVFTREELKSSQLKAD
                     DLENQQTNLQLPKSLPKRIEDLAVELTKNEATLIRKVEAVEQYLKTSGNFRYSKTDTG
                     HTPKEHDYVDYFLFDSKVGYCDNFSTSMVVLLRTLGIPARWTKGFTNGLRTGTDNQGN
                     EEYSILNSHAHSWPEVYFPGFGWLPFEPTPSFANPMGSQPVAETTETVQPAIEQPNES
                     ENMAETISSERSEVIPSEETTLTPAYKIVLFSLGVCLYVLLFFLLLFRKSLRWTSYLI
                     YLHFFASTNTIAYQKLLNHLETLVPRKPAESLQEYSLRIEQEFKLDLRFIRLTTQYEA
                     EIYGRQADPVNFDKKTYLEITHIIRKTVYKKVLTKGSRFKK"
     gene            complement(6818..8989)
                     /gene="copB"
                     /locus_tag="LP386_001461"
     CDS             complement(6818..8989)
                     /gene="copB"
                     /locus_tag="LP386_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HBL1918701.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHDHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKNQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
     gene            complement(9009..11195)
                     /locus_tag="LP386_001462"
     CDS             complement(9009..11195)
                     /locus_tag="LP386_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HBL1918702.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKSKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGLIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMSSSLASIAQTIELSRVTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            complement(11195..11404)
                     /gene="copZ"
                     /locus_tag="LP386_001463"
     CDS             complement(11195..11404)
                     /gene="copZ"
                     /locus_tag="LP386_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HBL1918703.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(11417..11857)
                     /locus_tag="LP386_001464"
     CDS             complement(11417..11857)
                     /locus_tag="LP386_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HBL1918704.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(11931..12404)
                     /locus_tag="LP386_001465"
     CDS             complement(11931..12404)
                     /locus_tag="LP386_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation family protein"
                     /protein_id="HBL1918705.1"
                     /translation="MGRENRPSQGRSKKSPAFRIQAKKWFLQEQQSFMVSNPSWIVEG
                     NYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLKRKINKKSRPDMPESFSEKLNRK
                     YLEFLSFIWHFEGNNEPKIQQLIQVANARNKLIILKTRREKQEFLTKLKIESKNN"
     gene            complement(12714..14180)
                     /locus_tag="LP386_001466"
     CDS             complement(12714..14180)
                     /locus_tag="LP386_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1918706.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(14491..16575)
                     /gene="cadA"
                     /locus_tag="LP386_001467"
     CDS             complement(14491..16575)
                     /gene="cadA"
                     /locus_tag="LP386_001467"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBL1918707.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKKRNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTAEGLMTVNPEDVLIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     RAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDPTGIDPKKFMQYVASAEQFSTHPIAQSVLEGYAGPLL
                     PTANIQEFAGEGILAEVDGKQVLVGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGY
                     LVIADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDK
                     VQRLEEILQSNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQP
                     SKIAEAIHLAKKTLKIVKQNIVFAIGIKILVLSLGAFGFASMGDAVFADVGVTVLAVL
                     NAMRSLHVKNKR"
     gene            complement(17099..17458)
                     /locus_tag="LP386_001468"
     CDS             complement(17099..17458)
                     /locus_tag="LP386_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HBL1918708.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(17488..17829)
                     /locus_tag="LP386_001469"
     CDS             complement(17488..17829)
                     /locus_tag="LP386_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918709.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AITKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            complement(17826..18500)
                     /locus_tag="LP386_001470"
     CDS             complement(17826..18500)
                     /locus_tag="LP386_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBL1918710.1"
                     /translation="MKKRILFIGDSITDAGRYRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIVAVDFFSGDKNE
                     RKKSEK"
     gene            complement(19295..20593)
                     /gene="asnS"
                     /locus_tag="LP386_001471"
     CDS             complement(19295..20593)
                     /gene="asnS"
                     /locus_tag="LP386_001471"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HBL1918711.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKITFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(20633..21823)
                     /locus_tag="LP386_001472"
     CDS             complement(20633..21823)
                     /locus_tag="LP386_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBL1918712.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNSEIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(21844..22371)
                     /locus_tag="LP386_001473"
     CDS             complement(21844..22371)
                     /locus_tag="LP386_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HBL1918713.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEETDHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(22418..25207)
                     /locus_tag="LP386_001474"
     CDS             complement(22418..25207)
                     /locus_tag="LP386_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBL1918714.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDSSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAIYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKEIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHAFFADIAHRGTGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLVQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(25354..25554)
                     /locus_tag="LP386_001475"
     CDS             complement(25354..25554)
                     /locus_tag="LP386_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL1918715.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(26006..26326)
                     /locus_tag="LP386_001476"
     CDS             complement(26006..26326)
                     /locus_tag="LP386_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918716.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(26627..27745)
                     /locus_tag="LP386_001477"
     CDS             complement(26627..27745)
                     /locus_tag="LP386_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918717.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            28216..29523
                     /locus_tag="LP386_001478"
     CDS             28216..29523
                     /locus_tag="LP386_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBL1918718.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFDNLF"
     gene            29642..30841
                     /locus_tag="LP386_001479"
     CDS             29642..30841
                     /locus_tag="LP386_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBL1918719.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYAWQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(30868..32136)
                     /locus_tag="LP386_001480"
     CDS             complement(30868..32136)
                     /locus_tag="LP386_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HBL1918720.1"
                     /translation="MEKQLPSPMRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLITLTL
                     FGTITTHLFGGSVGREGTAVQMGGSLADNTARLFRLDKAEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
     gene            complement(32299..32946)
                     /locus_tag="LP386_001481"
     CDS             complement(32299..32946)
                     /locus_tag="LP386_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HBL1918721.1"
                     /translation="MEQTIKPYQYFFIKREVEQLLNAYSSVNDPKTVQTVQALAAEKI
                     RDILNHELPEIDTFLTTVLDVKLTKAQAERALEKLKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQEHTYIGWNDPGTQKKFMVYYEDEKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     gene            complement(33354..33857)
                     /locus_tag="LP386_001482"
     CDS             complement(33354..33857)
                     /locus_tag="LP386_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBL1918722.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(33980..34744)
                     /locus_tag="LP386_001483"
     CDS             complement(33980..34744)
                     /locus_tag="LP386_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HBL1918723.1"
                     /translation="MKEIQSVKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLAEVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSSADQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            34851..35126
                     /locus_tag="LP386_001484"
     CDS             34851..35126
                     /locus_tag="LP386_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HBL1918724.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            35842..36792
                     /gene="yidC"
                     /locus_tag="LP386_001485"
     CDS             35842..36792
                     /gene="yidC"
                     /locus_tag="LP386_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBL1918725.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVIMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPADNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
BASE COUNT        10593 a         7758 c         6535 g        11967 t
ORIGIN      
        1 gtcaaggaca atcggaatag catacggaaa gaagttctgc accttataaa atttgtcaaa
       61 aaaactgttg ccattccaag tgaaaaaaag atcaatgaat caactagaaa actatataga
      121 agagcaaata aaaaagcact caaattgagt gcttttttaa gctcactatc actaaaacta
      181 tcactaattt tatttataag cgaacatgtt tctatcactg attttttaaa tctagcgaaa
      241 aacccttatc ttaaaggcgt tcgttcaatt ctttggcaag gtcttcaaag cctggcttgc
      301 ctagaagtgc gaacatggtt ttcttatagc tcatgtagaa aaattttctt gatgatgatt
      361 ttatccatca attgagattg actgttttgc tctcctatga tttcagctat gattgtccga
      421 ttttgcggtt ttcttcttaa ctggtagttg attttcccag tttccatcaa ctcgctaagc
      481 atatccacga ctccgccaaa tccggtcttt ttcgtaataa aacctagtgc taccattcgt
      541 tcatctagat tttttgctgt aatcgtcaca ccagtaatga gcgagtgctg taatgtttgg
      601 gccagctctt ccatcccttc agcattggat acgacggaag ctgttttgtt aataggttct
      661 tcgtttattt cttttggttc tttcctctcc actttcactg tttgacgaag gacatctagt
      721 tcttgcaaga gcgtttcgta ttgttcttgg gtcagcatca cgccagctac tttttcacga
      781 ttaaatatat atacgccagt tcccgcgtct cgcgcttgag caaatacatc catcggcgat
      841 cgtttcactt ctgtgatcga agatgtggga acttctaatt tctttaattc caatggattt
      901 cctcctttac taatcgcttt ttattatagc acagactgac ttgttttgat cttttttcca
      961 aaggttttat cggtttttgc ctaaccagta attgatatcg gtaagaagtc tttcgatacc
     1021 aaatgaagga tggtacagat acgttttttg atcttcgtta tggtctagtg gaaaaaaatg
     1081 atcggtgatc actagatctg cataccgagg cggcttattt cgagtacata catgtataga
     1141 gatccgtttt cgatgtctta gcgttttgtt cagtacccca gcaagtcttc ttgcttcttg
     1201 gtgttcatag cgaaaaaaaa agacgatttt cacttcagga gggtggacat ctaaataccc
     1261 tcgttcctgg agtgttttca gtaaaagcat cccccactct actgcggggt gtgcaaatgc
     1321 ttgttggatc gctagccgaa attgatatag tttatctttg gaattgggaa atttttctaa
     1381 tgtttcctga taataacgaa cttcttctat cagccggtca tggataccaa ttacgtaacg
     1441 aagccattct tggtaaagta cttttgtcag ctttgatttg ttttcgctct caaattcgct
     1501 attcagccaa aacagcgaat caagcttttc agtcacaatc gtcaatttcc gatagtcttg
     1561 tgtctcttct atccgtttcc accgcttttc agtaatctgg ttacagctca agcgcaaaat
     1621 tgctagataa tttttttctt ttattggcaa aatctgctct tctctaaata gcaattcagg
     1681 aaacaattca aagaatagtg ttcgactgtc tcctaaaatc tcgatttctg ccggatcctt
     1741 tctttgcttc aataattgga tgaacatctc agaaaaggac tgctctccat catctgcaaa
     1801 aaaatgcgga aaatctttca aaaagcaaaa cagcagatat cttacttttc tttctgaacc
     1861 aaagatctgt gcttttttat aagaaaaaga aaggtggtac tcgccaaacc actttctcaa
     1921 tcgctcttgc gtagaacgat cgtacttctg ctcgtaaggt tcattcaata gcagattttt
     1981 cagtaaacaa aacgggggtg attggatcag aaaaacaaac aagagataag gttcgctata
     2041 tccttgatca taaactaact gaacggtttt cttatgaaga atcagctgga tgggacagtc
     2101 gctttccgcc aaacgtttca gatgccgatc cactgtttta acatcgattt tcagttcttc
     2161 agctaaatca gcttttcgcc agatcaaatc tttcattaga ttgattagtg aaaataaatt
     2221 ctgtgcattt tttgataata gtttttgcca tctcatcgat catttctcac ctgatttcta
     2281 aacatattgt ttgatcaaaa tgggttcact cctaaaaaga taaaaaactc cctttctatt
     2341 tatttaaata cgcaaatttt cctcattatt tttaatttta ctcaatttaa tcgtattctc
     2401 atttcaaaac gaatgtactt taaaaaaaca taataaaatc actttgcttg taggatgtat
     2461 tcccttccat tacaatgaaa taaatagcaa ttttatgaga aggtgatgtg aaaatggaag
     2521 aaaaaatcga agaatccaaa caaaaaatcg atcagttgat acaagaatta gaaaaagcgg
     2581 tcatcggcaa acgttcaact atccaattga tgatcgtggc cctattagca ggtggtcatg
     2641 tcttattcga agatattccc ggtgtaggta aaacgttact ggtcaaagca ctagcaaaag
     2701 ctgtacaggg aaccttcagc agagtccaat gtactcctga tctgctgcct agtgatattc
     2761 ttggtttttc cgtatacaat tcacaatcaa aagagtttga atttcgtccg ggaccgatct
     2821 ttaccacgat cttgttggca gatgagatca atcgcacgac tcctcgtact cagtcagcac
     2881 ttttagaagc aatggccgag aatcatgcaa cgatcgacaa caatacatac cctctagaca
     2941 atcatttttt tgtcttagct acgcaaaatc caatcgagta tgaaggaaca tatcctttgc
     3001 cggaagcaca gctcgatcgt tttttattcc gactacaaat cggttatcct tcttttgatg
     3061 acgaactttt gctactttta gataaattcg aaaaagtgtt ggataactta aatgaagtat
     3121 tgaacagtta tgaaatagaa gaaataaaaa caaatgtggc gaatgtcttt gtcagtcccg
     3181 aagtggcatc ttatgccttg cagttagtgt cagcaacaag aagccatgct gccatccagc
     3241 ttggcatcag tccacgagga agcctttcct ttattcaggc agcaaaagct tatgctttaa
     3301 tccatgggag aaattacgtc acgcccaaag atttgcagga tttagttcct tacgtgtttt
     3361 cccatcgcct gattttttac gatcgttcat tgaaggaaga cgaaaaaaaa caaatcattc
     3421 atactcttgt tgcacaaatt cctgttcctg tgaggtagat tgaggtagat aatggaaaaa
     3481 atcaaagatt atttcattaa ttttgtgtta tttctggtat atttcatcat tgtgcttttt
     3541 gctcttgtat tcaacaattc tttaggctgg ttcttgttgg ccttttttac tctttatgta
     3601 tcatggagct tgatttcatt aagcagcttt ctaaagaaac tttcggttac ttgtacattg
     3661 cagccactcg tttatcgcaa aaaaagtatg caggttattt tttccatagc aaaaaagaga
     3721 actttttctt tacctctccc tcgtttacaa atcggcttcc cagcaatctt tgcagaaaaa
     3781 aaacaagaga ttttgattct tacaaataaa ccgcaagaag tccaattgct ttggcagcca
     3841 aaagaaagag gatgccatga aacattaact gtcattttta cagcctatga tagtctagga
     3901 cttttcagaa aaagtgcaaa aagagagatc tcttttcctg tgactgttct gcctgctttt
     3961 tgtaagattc aagcagaaaa attacagaga gttctggaaa aaaaacagca gctgaacgcg
     4021 taccaaagag gtcttgattt tcgggaacat cgcgcttatc gtccaggtga ttctttcaac
     4081 cgaatcgatt ggaaattgtc tgctcatact caagagtggt tataccgtga atacgattat
     4141 caagaagaag aatgttctcc tcttttttgc ttttggggtt cgcacagtcc aaaatttgaa
     4201 cctctgctag acttgtattt ttctttatgg catttgagaa aagaaaagca gccggaactt
     4261 ctgatattag gcaaccgcgc ctttcatggc aaagaccccg gtcataccta ttttgcttct
     4321 ttggaagctg gcgatgagaa agcttttttc gcacacctaa aaaaatatgc aaaaaaacaa
     4381 atcgtcctct ttgttcctga gaattctcct gaagtctcag aagctattga aacattgtca
     4441 aaagatcgaa cggtttatct tgtttatttc gtagaaaaac aactcatggt ccaagaaaaa
     4501 gacaagatat gttcattgcc aggaggtgaa tggattgacg attaaatggg aaaaatggct
     4561 gtgtggcgtt tactcctttg tgatactaag tgtaggtgct ccgatatttg tagtagctaa
     4621 tcaattgcaa aacagctacc ttcttatcct aactattggt gtcctatgcc ttattgtctg
     4681 ctgtattcct aaaaaatggg tacgtttgct gctttctttg ccagtaatga taggttgttt
     4741 gtttttgtat tttccttcga agacattttc cttattatgg atcttacagt ttttttcgtc
     4801 agtcacagag gaattcttcc atctatccca aggtaaactt tattatttgc cagaaaagac
     4861 agcttttttt ctcataatgt tgctgatcta tttatttatt acattgaccg tggattacga
     4921 ctatttgtac gcaccctttc tttctttgat ggcttacttc atgatgctta ccgtttttcg
     4981 ggaaaaagat ttactgtacg aaatgattgc ggtagtaact gttttgttcg tgtatctggc
     5041 agcaaggcaa tttttctcca tgcggttgtt gtcgggaaac actcgattcc agtcattgac
     5101 tacagttctg cttatttgtt tcttaactat tagcgctatc ttgcctttat atcttccgaa
     5161 agtacaccaa tctctcgagg aaacgagtga accgatccga gaatatctta atgatgaagg
     5221 gctttatgat acactccatg agtatcaatt aaccggaagt gcaagaacag gcttcagtga
     5281 gaatgatgaa cagcttggtg gacctttata tgataatggc gaagttgttt ttacagcgaa
     5341 ccaaaaagga aatggctatt ggaagatcga aaataaaaat cattacaccg gttctggatg
     5401 gatagaagat caggacgcac ccatccaacc aatccaagaa ttccctgttg acatcacgag
     5461 ctaccaaacc gttatggaag acaaagaaaa cattacattg accctaaaaa aacaagcttt
     5521 cttaccttat ccttatggaa atactacctt gactgatttt tcattagcta gtggacaaac
     5581 gctttactat ttgcctgaaa gccagcgatt cattcctgtc ccgaatgaat cgacacgttc
     5641 tgcaacttta caaacagaaa ggttagtttt tacgagagaa gaattaaaaa gcagtcagtt
     5701 aaaagctgat gatttagaaa atcagcagac aaatcttcaa ttgccaaaaa gtttgcctaa
     5761 acgtattgag gacttggcgg tcgaattgac caaaaatgaa gcaactttaa ttcgtaaagt
     5821 cgaagctgtc gaacagtatt taaaaacaag cggaaatttc cgctattcca aaacggatac
     5881 cggacatact ccgaaagaac acgattatgt ggattatttc ctctttgatt caaaagtcgg
     5941 ctattgtgac aacttttcaa cttctatggt cgtccttctt cgaacacttg gtatcccagc
     6001 tcgctggaca aaaggtttta caaatgggct cagaacaggc acagataatc aagggaatga
     6061 ggaatacagc attctcaata gtcatgctca ttcttggcca gaggtatact ttcctggatt
     6121 tggctggctt ccatttgaac caaccccttc atttgccaat ccaatgggtt cacaaccagt
     6181 tgctgaaaca accgaaaccg tccagcctgc tatcgaacaa ccaaatgaaa gcgaaaatat
     6241 ggcagaaact atttccagtg agagatctga ggtcattcca tcagaagaaa caacactcac
     6301 accagcttat aaaatcgtct tattcagcct tggggtgtgt ttatacgtct tgttgttctt
     6361 tctattgtta ttcagaaaat ctctgcgctg gacaagttat cttatctatc ttcatttttt
     6421 tgcttctact aatacgattg catatcaaaa acttcttaac catttggaaa cattggtacc
     6481 gcgcaaaccc gcagaatctt tgcaggaata tagcctgcga atagaacaag aattcaagct
     6541 agatctgcgt ttcattcgat taactactca atatgaagca gaaatatatg gacgacaagc
     6601 agatccggta aatttcgata aaaaaaccta tttagaaatt acgcatataa taagaaaaac
     6661 ggtatacaaa aaagttctga caaaagggag ccgcttcaaa aaataagata aaatttctgg
     6721 agaatctact tctggaatgc cgagaaccag ctgcttgagt atcgattatt cgaaaaaaag
     6781 gttgtgacac gttttttgtc acaacctttt ttcattatta tttgattttc aatgtcaaag
     6841 catttagagc tacaactacc gtacttaacg acatcaagac agcaccaact gctggactta
     6901 atatgatacc aattggcgca agaattccgg ctgctagcgg aattgcaaga atattgtaac
     6961 ctgcccccca ccagaggttc tggatcattt tctttcgcgt ttgcttggct agatcaagaa
     7021 aatgcaaaat atcttttgga tcgctgtttg tcaatacgac atccgcagaa tcgattgcga
     7081 tatctgtccc tgcaccgatt gccatcccga ttgaagcacg ggctaaactt ggcgcatcat
     7141 tgatcccatc acccaccatg attacttttt tcccttggtc aaggtatttc tggacaacag
     7201 cttctttatc atctggtaat aaaccgccat aatattcttc gatccctaaa taatctgcta
     7261 ctgcttgggc agcgttttta ttgtcaccag taagcatgac aggagtgatt tttctttctt
     7321 tcaatgttcg gataaattct tttgcttctg tttttactac gtcacctaaa gcaacgattg
     7381 cagctagatg attttctaaa atcaggaagc tgatggtatt tccttgttct tggtaaggtt
     7441 tcaataatgc ttgttctacg tttaatccga gacgctcaac ttctttttca ttaactattt
     7501 tcacttgttg gtttttgact gttgcctcta gcccaactcc tgaaagattt tttagatttt
     7561 cggcttgata aggcttgatt tcatgttctt tcaaataatt cataatacca acagccaatg
     7621 gatgattggc attcgcttcc aatgctccta aatattgaag gatttcattt ttattgaacg
     7681 catcatcaag tacttcgaca cccgttacag taaattttcc ttctgttagt gttcctgttt
     7741 tgtccagcat gatcacatct agatcattgg cttgctccag tgcattgcgg tttttcaaaa
     7801 gtaatccgtt tttagctgct attgatgtag agcgagcaac aactaatggg atagctaaac
     7861 ctagagcatg aggacaggcg atgataaaga ctgttaccat acgttctaat gcattaggaa
     7921 gatctgtcaa gaacaaccag gcgatgaatg ccaggatacc cacaattaat gcgacataaa
     7981 acagccattt tgccactttg tcagataatg actctagctt ggatttttct ccttgtgctt
     8041 ttcgcaccat ttccataacc ttcgctagat aaccattttc accagttcca gttacttcga
     8101 tttcgatcgt tccatcccca ttgatagaac cgccaatcac tttgtcattg gcttgttttt
     8161 tgattcctct tgattcgcca gtcacagctg attcgtcaac aattgtttca cctttcaaga
     8221 ttacaccatc tgttggcatt ttatcaccag accggacgat caaacgatca ccttcgttta
     8281 cttctttcaa tgaaactgtc tcttcttttc catctttcgt caagcgtttt actgattctg
     8341 gcagtaattc tgctagtttt tgtaaagcat tgctggcatt cgacacagca ttcatttcaa
     8401 tccagtgacc tagtagcata ataacgatca aagtagccaa ttcccagaag aaatccatga
     8461 cgtgtgtatg tggattgagc agatttgcga taaacgaata gacactataa atatatgcaa
     8521 ctgtaatccc catcgcgatc agtgtcatca tagcaggact tttttgtttc aattccatct
     8581 tagctccact taaaaatggc tgaccgccat agataaatag tatagttgct aagatcaata
     8641 cgagccaatc agaaccagga aacgttactt gaaatggaaa ttccattccc atcattggtg
     8701 aaaaaagaat gattgggata gctaggataa gcgatagcca aaatttttgt ttgaaatttc
     8761 ccatgtgcat ggaatgatcc atgccgccat gatcgtgatc catgtgcatc gaatggtcca
     8821 tttgtttgct gtttgctata tctccatggt tatgtcccat gtgcatggaa tggtccatct
     8881 ggctatggtc atgtttcatc tccatctgtt tttcatgaga ttctgtactt tctttgttta
     8941 ctacttcttt tttatgttca tgttttttct ccatatcgtt cccattcatt tttactccat
     9001 cccttctctt actttttcat gtgccgattt aagctcaggg agttcaacaa tacactgacg
     9061 gaactaaacg ccatcgctcc tcctgcaatg attggattca aaaagcctag tgcggcaaaa
     9121 ggaataccaa tcgtattata gacaaaagcc cagaaaagat tttgtttgat ttttctcaat
     9181 gtcaccctag acaactcgat tgtttgtgca atggatgcca aactgctact catcagcgtc
     9241 acatcggctg tttccatcgc gatatccgtt ccacttccca ttgccatacc aacatcagct
     9301 aatgctaaag ccggtgcatc attgattcca tcgcctgcca taccgacttt tttgccatct
     9361 ttctgaagtt tttctacgta ggctgcttta tcctctggaa gtacttcagc aaagatatgc
     9421 tttggatcaa taccaacttg tttaccaatc gtttcggctg ccagtttgtt gtctcctgtc
     9481 agcataaaaa catctaatcc tttattctgg agctgcttga ttgcttgttt ggcttctagt
     9541 ttgatttgat cagccacggc aatcaacccg atcacttgct tttcatcagc taaaaacatg
     9601 actgtttttc cctgctgttc taattctaac gcgtgttctt ggtattcatc aaatgatagg
     9661 ttcaattcaa ttaatcgttt acgtgtaccc gcaaaatagc gtactccgtt aatcgtaccg
     9721 ctgattccag cacctgggtg agctgtaaaa tcaatcatat cgtatgttgc tgcttcttgc
     9781 agttttccgt attccacgat tgctttacct agtggatgtt cagaagcttg ttctaaagta
     9841 taaaaaatag ataggacttc tttagaaccg actagatctg taactttggg ctttccttct
     9901 gtaatcgtcc cagttttatc caaaacaatg ctgtctaagt gagcagctgc ttctaatgct
     9961 tctccgcctt taattaaaat tccatttcgt gcaccaacac ccgttcctac cataatagct
    10021 gttggagtcg ctaaacctaa tgcacatgga cacgcaatga ctaatacaga gacactatgg
    10081 atcaatgcga gttgccaatc accagtgatc aaacctgtag ctatgagcgt gataaacgcg
    10141 atgactaata cgatcggaac aaaaatccct gagatccgat ctgcgatttt ttggattggg
    10201 gctttgctcc cttgagcatc ttccaccatt tgaatgattt gcgctaatac tgtctgcttg
    10261 ccgacttgtg tgacttccat gtgtagcaga ccattcgtat tgattgtccc gccaaaaagc
    10321 gtgtcatccg gattcttttc tacaggaaga ttttcaccag taagcatact ttcatctatc
    10381 gcactgcttc ctgaaataat tcgaccatct gctggaatct gctcaccagg acggatgact
    10441 agttgatcac caacgactac ttcttcaatc gctaacgttt cttctttccc gtttcttatc
    10501 acttgggcgg tttttgtttg aagagacatc aattgtttga ttgcattacc tgttttcgtt
    10561 tttgctgtat gttccaaata tttgccgagc aaaatcagcg tgatgatcat actgctgctt
    10621 tcaaaataaa gatcttgggg gtgtccacgg aaaaatccgt tgtaaatgct caatgcaaag
    10681 gcagccgatg ttccaattgc taccaataca tccatatttg gtgctttcga cttgattgca
    10741 tggtacgcac ctttataaaa acgagcaccg acataaaatt ggacaggagc agacagcact
    10801 aactggacga ttggaaaatg aaaaaagtga acaatcgccg catggcttcc taacatcata
    10861 gcaatcattg acaacatcaa cggcaaagtc aaaaccgtac tcaatataag atcgaatagc
    10921 atttttttca aatacgcttg cttttcttct gcaatttttt gtttgtgggc ttcatcgtac
    10981 aaaattgcac catagccgat gttttctacg ctttggatta atttttcagt ggtcgtccct
    11041 tcatatttga cacttgcttt ttcagtggcc aagttgactg tggcattgac cacaccaggt
    11101 tgtccgttca gctctttttc gatcctagca gaacaatttg cacaagtcat acctgtaatg
    11161 acgaacgtat ccattttggt ttctgctgtt gccatcaaat cacctctgct ttataaccca
    11221 atccattgat tgcttgacaa atcttttcgg attgaacttt tgtttcatca aacttgaccg
    11281 taccgtttgc ttttttcaaa tttactttca ctttttgcac gccgtcaagt gcgcttactg
    11341 tttcttctac tcttgctgca caatgattgc agctcatacc ttcgattgaa aattgttgtt
    11401 tcattttttc ttcctcctat tgatgttgtt tacattcaca ttgacctggg atacagttac
    11461 attcgatcgt atctactggt tgcttttgtt ccagttgttt caaaatctca ttgatatctt
    11521 cttgagtcaa agtggcttct tctactagat ccgcaatcgt ctctccaatc ctttttgcac
    11581 agatatggga aaaaagattt tccgtcgcac tgcgaactgt ttccatctcc gagacagctg
    11641 gatgataaat gaattttttt ccttcttgtt ctgtccagat cacttctttt tttaccaaac
    11701 gacccagcaa agttttgatc gttgctggtt tccaatccat cgaatcagct aagatctgcg
    11761 tgatttcttg ggctgtcgtc tgtccaagtg tccaaataac acgcatgatc tcccactctg
    11821 aatcactaat ctttactggc gttttgactt tttccattta tttcacacct ttcgtttaca
    11881 aatgtaatca ttaacttatg aatacagatt acacttgtaa acaaaaactg tcaattattt
    11941 ttgctctcta ttttcaattt agttaaaaat tcttgtttct ctcgtcttgt tttaaggatg
    12001 atcagtttat ttcttgcatt agctacttgg atcagctgct gtatttttgg ttcattgttt
    12061 ccttcaaaat gccagataaa agataaaaat tctaagtatt tcctgtttag tttctccgaa
    12121 aatgattcag gcatatctgg ccgagatttt ttgtttatct ttctttttag agaacgccaa
    12181 actactcggt agatggcgag ataacgcggc actttaagcc aaatgatctt atctgcttct
    12241 ttaatccttt cctctaacgt agaagtataa tttccttcaa cgatccatga cggattagat
    12301 accataaacg attgctgttc ttgcaaaaac cacttttttg cctgaatgcg gaaagccggt
    12361 gatttctttg atcttccttg cgagggacga ttttcccgac ccactttgtc caatcacgat
    12421 gatcttcatt cttctccctc acttctcttt ggaatttggt tcgatcatac cacttataac
    12481 gccgcaaaaa aacaagggac tgtgacaaaa gtcgtgtcaa agtcccttgt ttcgaataaa
    12541 tggtgttcaa tcagctgacc ttcagcatta gctcaaaaaa cggcaaaata tgaggagcta
    12601 tttttgtttg gctgttctta ttacttgatg caggacagct ttttcacaac ctctgattca
    12661 cggtgttcca gaagtagctt ctgtcacaac ctcttgtaac aagtatttct attttaaggc
    12721 tgaaccactg tttctggttc agtaatttct ttgtttttgt ctcgacgagc aattgctggc
    12781 aagatcatac ctaataagat caagacaatt ggtgtgatga tattcgtgaa taattggaac
    12841 caccatgctt taggatcagc agtataatct acttttggca ccattcctag gatacatgca
    12901 aacgcagtga aggcaaagca ccaagcacca aagataaaac cgatttttgg atttttaaca
    12961 aatttatatt cagaattgaa tttcttataa gctttattca acatcatata tgccaagaac
    13021 acccataggt aacgcattgg catgacaact gagttcaagt tcgtcaacca ttttactaat
    13081 tcattcatat ctttgatacc aaagatcggc aacaaaataa tgattcctac tagtatacct
    13141 gtcagaagat aaccattcac caatgtacct ttacgattac gtttacgtag ccagtttggt
    13201 acaaattctg gatccgcatc tgctaacaag atttttagtg gtgcatcaat tgaaaaggct
    13261 aatgcggaga tttgtccaat catgtttgtc aatgcgtaaa tgatcatcaa tgagttaccg
    13321 ataccatagt aattacctaa aatttgaaaa gcactgtatg ccccatttgc catcaagtct
    13381 ttagggatat tatcgctagc aaacagcata cccattgcga ctgagcctaa tacagcacaa
    13441 atccctacca ttgctgctaa gaagatcatc cctttaggaa attcctttgc aggatttctt
    13501 gtagagttga cataagggga tattttttcc gcccctccaa ctgcaaatac tagcatcgaa
    13561 acggttgtga aataactgaa atcaaatgtt ggaatatatg ttttcacttg attcatatgt
    13621 ggtgtggcaa attccatcgt tggattgatg aacggtgccg ttacagctaa aagaataaat
    13681 aagatcgaca tgacgaacat cgctgttccg gccagtccgc caatcacttt caaagtagaa
    13741 agtccttttg ttgataaata taaaaaggca agaaatataa taagtgaaat aactgctacc
    13801 atttgtactg acatcgtatt tacgatattt ccatttcctt ggactgccca accaccagca
    13861 atcagaattg cttgaggctt ttgtgccaaa taaggaatat ggacgaccca gtaagtccaa
    13921 gcggcatagt atgccagtcg tttattagat gtcgtatttt cgacccatga actgacgcct
    13981 cctttactat ccttgaaggc tgatcctaat tgtccaacga tcaatgcgta tggaataaaa
    14041 taaatggcca aaatcaatag ccaagaggtg acaactgata ctccttgctg agcatagtta
    14101 ttaactacat tccccatgcc ccaaaccatg ttaaatgcaa ttaacgcaac agtaaaccag
    14161 cgtaattgtt tgttgttcat tcgttctctc ctttatgata aaaatttgtt atccagatgt
    14221 aatcatattc aatttttaac aaacttacaa gacagtgtta ttttatgtgt gtattctttt
    14281 atttaataca catcgttttt tcatattttt tccatcaaaa aaataagtta ttttctttta
    14341 tttcattgac cttattgaat ttcaagctat tttgaatttt ctgcaaaatt aaaaacatta
    14401 gttattttat aatcctatct attttcttta catttttcat taagaaaagg atataaaaaa
    14461 aagaggacgt tcattcgtcc tcttcattga tcaacgttta ttttttacat gcaagcttcg
    14521 catggcattc aaaacagcta atactgtcac cccaacatct gcaaatactg catctcccat
    14581 tgatgcaaaa ccaaaagcac ctaaggaaag taccaaaatt tttatcccaa tagcaaagac
    14641 aatgttctgt ttgacgattt tcaatgtttt ctttgctaaa tggattgctt ctgcaatctt
    14701 cgatggttga tcattcatga tgactacatc tgctgcttca attgcagcat cgcttcccaa
    14761 tccacccatt gcgattccta catctgctct tgctagcacc ggtgcatcgt tgattccatc
    14821 tccgacaaat gcggtctttt tattgttact ttgtaagatt tcctctaacc gctgcacttt
    14881 atcttctgga agcaattcgc tatatatctt gtccacgcct acttgcttcc cgatatgatc
    14941 agcaattttt ttcgagtcgc ccgtcaacat gactgtgttt ttcacaccag cctgttttaa
    15001 ttgaaccaat gcgtctacgg catcttcttt caaggtatct gcaataacaa gataaccact
    15061 gtaactttga tcgatcgcta gataaagcaa tgtaccgatt tcttgacttg aaggaaaaga
    15121 gatttcaaat ctttccatca atttgtgatt acctactaat acttgtttgc catcaacttc
    15181 agctaagatc ccttcacctg caaattcctg gatattagct gttggtaaaa gcggacctgc
    15241 gtagccttct aaaacagatt gagcaatcgg atgtgtagaa aactgttctg cacttgcaac
    15301 atattgcata aatttctttg gatcaattcc tgttggatcg atcgtctgga tcgaaaagtc
    15361 acctttcgtt aatgtgccag ttttatcgaa taccactgtc tcagtttgtg caagcaactc
    15421 caagtaattt gaacctttta ctaatacacc gattttactt gctcctccga taccgccaaa
    15481 gaaactaagt ggcacggaaa tcactaatgc acatggacat gagatcacta aaaatgtcaa
    15541 tgctcgatag atccattcag aaaacgccgc tctagaaaca acaagtggag gtaaaacagc
    15601 taataaaacg gccaatccta caacgactgg tgtgtaatag cgcgcgaatt tagtaatgaa
    15661 attttcagct ggtgcttttt tactgctggc attttctact aattctaata atttgctgat
    15721 agtagaattt tcataagatt tttctacttg aactaaaaat ggtttatttt tattgataaa
    15781 tccgcttaat actgtttcac caacatatac agatttaggg actgattctc ctgtaagtgc
    15841 tgacgtatcg actaatgatt ctccttcgat gatcgttcca tctaacggta cacgttcacc
    15901 aggcttcaca agtacaaact gaccgatcag cacgtcttca gggttcacgg tcatcaatcc
    15961 ttccgccgtc tgcacgtgag ctgtttctgg acggatcgcc atcaattcgc gaatcgattt
    16021 tcttgaatga ctgactgcca atccttggaa atactcgccg atttgataaa atagcatcac
    16081 tgctacggct tctggatatt caccgatcaa catagcgcca atcgtagcaa cagacataag
    16141 aaaattctca tcaaagattt ttcctttgac gatattcatc actgccttct tcactacatc
    16201 atatcctatc agcagataaa tcaataaata ccctatcaag cgaattggtt cattaaaatc
    16261 aaataatagc aataaagcga tacctgcaag ggaaaataaa atccggaaca gcgtatttct
    16321 ctttttttca tttccatgtt cagatacttt ttccttatct atttctgtta ctttgacatc
    16381 tggttctaat tccttcacta ctttttttgt ttcttgttca atcgtagcca aatgatcttc
    16441 ctctgcgtca atcgttagtt ttccagaagt gaagtttacc gttgcttcct tgactccatt
    16501 gattttctga actccttttt cgattttcat tgcacagttc gcacaatcta aaccttctaa
    16561 tctgtaactt ttcattttaa tgacctcctc gcctcaacat atgaatatct cttcataact
    16621 aattataaat gaatggttat tcatatgtca aggtatccga aagaaaaaat gaaaaacatc
    16681 tgcatcggaa aatttcttcc atacagatgt tttggcttat tctttctttt tctcttcgat
    16741 cattgccact gctcttatcc aacccgcact tgccttcttg atcttgacag gatagcaact
    16801 aagtttgaag cctgttgctg gcaatttgtc taaattcatt aatttttcga taggacaata
    16861 tcttttttca atccctgcaa aatgtccttc ccagatatac gaagctccac tacgctttca
    16921 aaaatataga aagagttctt taatgaaaat tatttcaact ttccataaac agtaacccca
    16981 tataaataaa agacgtaaaa gtcacataga agaacttata caggaaaacg catagagtca
    17041 ggtgaaatac atgtatccca cctggctcta tgctttatct aacctttatt attctctttt
    17101 atacaatttc tgcaccgaat ggcatcaacg ccaatcgagc aagtttgaaa gattgcttgg
    17161 caaaaggtat ccctatgatc gtgatacata gaaggatgcc gctgacgaca tgtgcgagag
    17221 caattggtag gcctgaaacg atcagccaga tgatattaac gatcaatgac atgccagact
    17281 ggtgataaat tacttctttg ccaaaaggcg caaaagaaag ggaggcgatc ttaaaacatt
    17341 gcataccgat tgggatacct atgatcgtga tacaccaaag tatccccgct gctaaccagc
    17401 taagaccacc gattagtccg ccgaatataa accagatgac atttcctaaa caactcattg
    17461 tatttctcct tctattactg tttttgatta aaactgggca aaaattgatt ttattcttct
    17521 ttttttagct tccagcatca agtattctgc aaattttttt tggatttctt ccgtattttc
    17581 ttttgttact aatgtgtgtt ggattagttt tcctgatggt cgctgatcca atcgttcttc
    17641 tgactgttgc acgtccgctt gcgcaaatcc gataatccgt ttttcttttg ttatagcaac
    17701 gagcaatagt ttattcttat catttaggtc agctgccgtt tttgctttta cgaatgattc
    17761 tggatgatca gtaatcagct gattgatttg aggtaaatct tcttttactg cccaccttat
    17821 ttccatcatt tttcactttt ctttcgctca tttttatctc cactaaaaaa atcgactgcg
    17881 acaattgcat ctatccagct ttgtgcaatg atctcatgtc cgccaatcgt tgggtggacc
    17941 ccatcttctc ttgtatattt cgaaaaacca taagcaatcc ctaaagcatt gaatatacca
    18001 tctaaaggaa ccagcaatgc gccatattcc ttagcaagtt tacgaacaat ttggatttta
    18061 gggtctaagt ctttacgcca gccatgacgg tcgtcggtta taggaagtac aaacggctcc
    18121 atcaagatga tgttgcagat ttccgctgtt tgaagttcat ttagtaattt tcgataaacg
    18181 gattcaaatt gctgagcaga tttctcagtt ccgaatatag cctgatcgct agtattatgc
    18241 caggtatcat tgattccgat caaaatcgat acatagtcag gttgtaaagc taaacaatct
    18301 tcttgccagc gtacttgcag atctgcaatt ttgtctcctc ctatcccacg gttcatgcat
    18361 tcaaattcca tcgttggata ttgggagatt agttttccgg caatcaaaag tggataacct
    18421 ttacctagat cagttgcttc tgctcggtat cttcctgcgt ctgtaatgct atcaccgata
    18481 aataatatac gttttttcat ttgtcaaaaa ctcctttttg aataaaacga tgattttctt
    18541 ccttatatta tcccataagc cctatcaaga cgaaagagaa aatatatgta taaaaaatga
    18601 caccagccta gttccttcaa acaattgaat gaacgctcat caagtgtcta gttttttatg
    18661 ctattttttt cttaacgtgc cggattcccc ttgattcctt cgttgtttgg tccagagaga
    18721 tcgatcacac ccaagcttcc gtcaatcaga ccactgatga cgccatcgaa acatatattt
    18781 ataggctcat ctaagacttc tagtaaatgt ccctttacta atatctcttc tagattgctt
    18841 gggatagatt ggtcataact ttatctggtc cgatgatttc aagggtgaat tgaacttaca
    18901 tatggattat tgcatgctga aaatacggac ctactccatc ttcgaatgtt actattagtt
    18961 tgttttcagg tgctagatgc tgctttattt caacagcaga agcatcatca aatcagattt
    19021 ccatttgaat taccttcttt gtaaatgttt gattgattgc gatttcgtta tagaaccttg
    19081 tgaatcaaat agcaatttct tttgctttct tctcttgtct gctggaaact tccattatcc
    19141 cgtatttaaa aaaaagaact gcgagagttc gcagttcttt tttttaaata aacgttgctc
    19201 tccggccaca agtcacaata gtcatcaaac atgaaaaact gttttttgaa attactcctt
    19261 gtgactcgga gctgaacggc aggcgcacaa cctcttatgg ataaattcgg ttcaacaaac
    19321 gtgggaatgg aatagcttca cgtacatggt cgataccagc aatccaagtg actgttcgtt
    19381 caagacctag accaaaacca gagtgcggaa cagaaccgta tttacgtaga tcaagatacc
    19441 atgaatattc tttttcatcc aaaccgtgat tacggatttg ttctagcaag aaatcatagt
    19501 ccgttgcccg ttcgcttccg ccaataattt caccgtaacc ttctggtgcg atcatatctg
    19561 cacaaattac cacgtcttct cttgttggat gtggtttcat gtagaatggc ttgatggctt
    19621 ttggatagtt taggataaag acaggctgtt cgaatgaatt cgcaatgaac gtttcatgag
    19681 gtgaaccaaa gtcttcgccc cattcgatgt catcaaatcc atttttcttc agtaattcga
    19741 ttgcatcatc gtaagtaata cgagggaatg gcaattttgt ataagttttt aagacttctt
    19801 tgtctcgtcc tagtacatct aatgcgtatt cgcaatgatc taaaacattt tgtactaaga
    19861 atgctacata ttgttcctgt acttctaaac tttcttcttg atgagtgaaa gccatttctg
    19921 gttcgatcat ccagaattcg atcaaatgac gtcgtgtttt tgatttttca gcacggaaag
    19981 tcggaccgaa tgaaaagact tttccgaaag ccatagcagc agcttccatg tataattggc
    20041 cactttgaga taaataagct ttttgatcaa agtaatttgt ttcgaataga tccgtagtgc
    20101 cttctggtgc agaaccagtc aagatcggcg gatcaatttt gacaaaatga tgttgattaa
    20161 agaattcata cgttgcacga atgatttcat ttctgatctg cataatcgca tgttgtcttg
    20221 aagaacgcag ccataaatga cgatgatcca tcaagaagtc tgttccgtgt tcttttggtg
    20281 tgatcggata atcgtggctc tcgcttacca cttccacatt tgtaattccg atttcataac
    20341 caaattttga acgactgtct tcacggattt ctccagttac taacacggat gtttcttggt
    20401 gtagattttt agctgtttgg aaaacttctt ccgacacttc gctttttaca actacacctt
    20461 ggaaaaaggc tgttccgtct cttaattgta aaaatgtgat ttttccgctt gatcgcttat
    20521 ttgcgaccca agcgccgatt gttactgttt ctcccacatg gtttttcgaa tcgatgattt
    20581 gaatttgttc cacgtatgac tctcctttta tattccttga atttcttcag gattaatttt
    20641 gacttttact ctcaataaat tgcttgattc tgcgtaccgc ttcttctaac gtagcgcgat
    20701 cagtagcata actcatgcgg acattttctg gtgccccaaa gccttcgcca gtcacaagcg
    20761 ctacccctgt ttcttctaaa agatcttcta cccattgtgt gacattttca tatttacaca
    20821 tgcgtagcgt ttcttttaca ttaggaaaaa gatagaaagc tccttgcggc ttttcaagag
    20881 aaacacctgg cagttctgcc acaagcggat ataacgtatt caggcgttct tcaaaggcgt
    20941 tccgcatttc ttctactgta tcttgctcac ctttcaatgc ttcaacagct gcatattgac
    21001 tgactgctgt cggattactg gttgactggg aagcaacagc aatcattcca ttgatgatct
    21061 cagaattccc caccgcataa ccaatgcgcc agcctgtcat cgcatatgtt ttagacacgc
    21121 cattgatgat gatggtctga tttttgattg cttctgaaat cgttgcaatt ggagtaaact
    21181 cattgccatt ataaactaaa cgaccataaa tatcatcagc aactatcaaa atatcatttt
    21241 ttactgccca ttcaccgatt gcctgaagtt cattcttgct ataaatcatt ccagtcggat
    21301 tcgatggaga attgatgatt acggcttttg ttttttctga acgtgcttgt tctagctgtt
    21361 caacagtaac tttccagcta ttggattctt cccctttcac aaagacagga agtccttctg
    21421 ccagttttac ttgctcaccg taactgaccc agtaaggcac aggaatgatg acttcatctt
    21481 gcgggtcaag gatcgtttgg aaaagggtat acaaagcaaa tttcgctccg tctgttacga
    21541 ctgtttgtga aggttcatag acaagtccat agtttttctt cagataatca acgattgcct
    21601 gtcgaagctc tgggattcct gctgttggtg tataatagct agctttccca ttgcggattg
    21661 cttcgattgc tgcttcttgg atgttttctg gtgtcgcaaa atccggttct cccacagtca
    21721 aactcagcac atctctgcct tttgctttta atgccttggc ctttgccgca gctgccaaag
    21781 tgacagacgg ttctaatcgt tttgttcttt ttgataactc catcccattc attcctttac
    21841 cttttaaatt cccttgattg tcttgacttc atctccagat tcaaagccaa tcaggtaata
    21901 attcagtttc ccatttgttt cttttcctac tacttcccac acaggctgat catcatacat
    21961 ccctaaagca gctttttcga tttggatttc aggatgggcc gcagcaattg tctgttttgc
    22021 ttcgttttca gtcagtccct ttgtttgatc caatactttt actttttcac cagatttagg
    22081 aatgataacg gcgatttctt ttcctttatc atttgtacct gtcagtgaaa agtatgtctt
    22141 ctttcgagta aaccaataaa aatgatcggt ttcctcaaga tttgcatatt tctttgcgat
    22201 ttctactgct tctttcttcg cctgcaccgc cggacgactg gaacgcaagt aaaaaatcga
    22261 gctgatcacg atgaccgcta ataaaaatac gatcaagcca agtaacacgc gattaatcgt
    22321 tttttccttt gtctgttttt tcttcaaggg tcgtcgctcc tttatcttca ttccttttca
    22381 ttatagcaga ttttaattat gaaaaaagac agctcctcta acttccttct tcatttttct
    22441 ttaagaattc atggatatcc tgatagattt cctccatagc tagctctttg atcggtactt
    22501 ttttcggtaa tgcatggatg atccgtgcgc catattttgc agtgactagt cttcgatcca
    22561 aaataagcaa tacgccacga tctgtctccg tccttatcaa gcgacctaat gcttggcgta
    22621 acttcaaagc tgctttaggt acggattcct ggtaaaaagg attgatcccc tctgattcta
    22681 aataagcgtt cctagctttg accatcgggc gaagcggatt atcgaagggt aaacgtgtga
    22741 ctacaacgat ctgcaaagca tctccaggca aatctacacc ttcccaaaag ctgtcagcgc
    22801 caaacaatac gcttttttct gacaaaatga agcgtttcaa aagcttctcc cggcttccac
    22861 caaacccttg agctagtatt tctcgtcctt tttctagcat agacagatgc attttctgat
    22921 agaccttctg caaaacatca tgagaagtga ataacacaag tattggccga tcttcttgtt
    22981 cgatcagacc tgtaagtgct gtctctaaat aatcgatgta tgcttgattg ctgacttgat
    23041 ggacggcagg tgcctctttt ggcacataga tccttgcctg tttctcataa tcataaggag
    23101 aggcaatcac tttaagaggt gctgcttcaa tgccaagcct cttagagaga tagtgtcgat
    23161 tagggccgat cttcagcgtt cctccaatat aaagaatacg atcatatcga ggataccaaa
    23221 cagtcgacgg caacatagcc gcttggaaat catggagatg aaaaatcatc tgctgcgctg
    23281 tgttcccagg aacgaaccaa tggatcaaat gatctcgcca gtcttccagc cattgatcca
    23341 tcagcaagta ctgcttgtct aattgatcaa ataagctata taaacttgct aaatcgatcc
    23401 gcatctggtt tgtccagctt tcttggataa tctcaaaagt cagacgcatt tgtgactgta
    23461 gctgctgaat ctcctgataa aaaagctgca ggtgatcaat ggctgtccca gattccagtg
    23521 gcagctgatc cagcatctct tttgtcatca tgacttcttc tggatactgt ccgttgggtt
    23581 gcttgccgct cactaaactc attaatcctt ctgccataca aatctgtgct tcgcatagcg
    23641 cagaaagttc ttctcgataa atcgataacc agcgtaaggc ttcatgttct ttcggtaaat
    23701 agctttgtat tcggtcaaac agctgatttg gttcttctaa ttgctggatt tgtttatgga
    23761 aatagttaat acttaatcgt ttgtcattta ctttttcagc gatttccggc aaatgatgta
    23821 cttcatcgat caacaaaaat ggactagctg gaagcaatgg ttcttttcgc tgtgtttctt
    23881 gtactaaaaa cgcatgattg acaatcaaaa aattactttg cctgattttc ttttgcaaga
    23941 aacgaacaaa gtcttgttcg taaaacgact gatttcttgc taaaaaccca gtacctctgt
    24001 gcgcgatatc tgcaaagaat gcatggttca agtttgttaa atgtaattca tccaaatcac
    24061 cggtcttcgt ttgcgtcagc caaactaaga ccgccatttg atacaaagca tattgttttt
    24121 gttctggtgg ttccacaagt gttcctttaa atcgttgcag gtcgatatag tggcgataac
    24181 ttttgataat tacaggttgt atgggctgat ctagcaattg attcagcaat ggaatttctt
    24241 tttctatgat ctgctgctgc aaaactagcg aaacggtact gatgacagcg ggtttttcag
    24301 gtgtagccaa ataactcaat ggcaacagat aaccgattgt tttacccatt cctgtagctg
    24361 cttcgatcat caaatctttt gattcatctt ttgtgaaatg gtcgtagatc gcattcatca
    24421 gtctgttctg ttcttttcga tacatcagtg ttttaccaaa catcttttct tttgcttgtt
    24481 tttttcttgg atatgtccgc tcgccgtaat ggacggatgt gaatagttcc acttcttttt
    24541 tctgcaaagc tagcccatcg acgatttcta atgaggaatc aagtggctct ggtttttctt
    24601 tcatttcttc aatcacatga taaatgaaac gactcgtatc catacctgtg tgtctactta
    24661 atcgcgcaat ctgctctaac gtgatgattg gcaattttct catccgttct tcgatcagca
    24721 aaagaagttg acctgtcact tcggcatcac tatctgcctg atgaggattc tcatgaataa
    24781 atccaaggct ttctgacaaa tcagctaagc gaaagcttgg ttccgtcggc aagaaaattt
    24841 gtgcaagttc tactgtatcg atgcctggta tcttcaaact aggaagtccg catcgcatga
    24901 gttcatggtt caaaaaatta taatcaaaat aaatattatg cgcgacaaat atggtgtctg
    24961 ccaaaagatt gtaaatcgtt tgggcgacat cttcgaaata aggcgctttt tggacgcgtt
    25021 gattcgtgat ccctgttaaa tgctggattt gttttgaaat cttccgccct ggatgaatat
    25081 cgatcgaaaa acgtgaagtg atccgacctg attcaatcat gacgcagcca aattggatga
    25141 tccgatcttc ttttggattc gtcccagtcg tttcgatatc aacgactgca taagttcttg
    25201 gtttcaaaat atcttcctct tctcctgcct ctaatgttct tttgaaatta tactacaaag
    25261 tgcagaaaaa tactctcatc gctttttaaa gaaaatagac aaaaacgccc agacacgcaa
    25321 atgtctgggc gtttattttt tagtataggt taattaagct ttagtaacgt ttgttgcttg
    25381 aggtccgcgt tggccttctt caacatcgaa agttactgct tggccttctt ctaaagtttt
    25441 gaatccgtcg ccttggatag ctgagaaatg aacgaataca tcgtttccgt tttctgcagt
    25501 gatgaatcca aatccttttt ctgagttaaa ccattttact gtacctgttt ccataataaa
    25561 aatcctcctt gtgtatcaac acatattttg caattacttg aatggtgtat atctggaaga
    25621 tgtttatttg aaacaagcta ccacagatta ccgaacaaaa actactccta tagtatatca
    25681 taccgtttac aaaaaagcta gagtttttcg acttttttta ttaaaaaaag ttttctcagc
    25741 gattacataa agtgaaaaaa cgaacttttt ttaaaataaa cgacatattg ttcagttggt
    25801 gtttttttgc tctgatgttc ttctttaaac taaaaaaatt attctttctg actacttatc
    25861 ggttctgttt caacggtcga ggctggggaa gattctttag taggtctgat gttctcatgg
    25921 tatttctgat agcctatgac agtgaccaga agaacaaggc aaaccaatac gatcaacgag
    25981 attagttttt cttttttgct catatctata cctcataaat aacaggatga tgtccatcat
    26041 atttctgagt atgagtaaaa gcaaaagctg cagctgtaga atgtaagaaa tgccagcaac
    26101 tttcataatc acaggtcgga cagtaccaaa agtaaccaaa tcttggctgc aaagaccgtt
    26161 cttctgtttc aggaatcgca gaatcaagat ctgttgtctg tacataaaca tttttgtaca
    26221 gacgtgtgcc tgtaatagga gaccgctgtg tttcttcagc aaaaactggc tgacttgtta
    26281 aacttaggga tagaaacagc aaacaccata acagtctttt tttcataaag acctccttat
    26341 cgataagttt ttcccaatta aaatcatatc tcaagaacgc ccgttattca cattttgttc
    26401 ataaatgatg ttttttgtat cataatcgtc aaaaagaggt cgtgaccacg tcacaacctc
    26461 ttttttaaac ggtgttccag aagtagcttc ttcggaaata agccgaaatt tcacaaaaat
    26521 ttgagaaata atttttgtca atctcttctt atttcttgaa gctgaccact tctgtcacaa
    26581 cctcttcctt aatactcagg tcaaaacact gatttcacaa cctcttttaa taacgaagaa
    26641 tcgctgtcag actcttttca tctggcgcat ctttttgatc caaaataaac actttcccgc
    26701 cattaatgat cacatcatct gctaatgcat tcaacacttg acgccgatca tattctgttt
    26761 caggatcttc accgaaacca tcagctaagt ttgacgtagc gataaataaa tgtgacactt
    26821 ttccttcttt cgcagctgga acgatatcaa ctaactgatc gatgaatttc ttatctaaga
    26881 gtttattgta ttcttttgat tcttgagctg cgagttcact tgacagcttc ttcgcccctt
    26941 cttcgatatc tctaaaggat agctgcgcag gagaagcaga aatcgcaacg tctgcacaat
    27001 aatagggatt tttagcaatt tttttgaaca tcgtctgatt ttctggtaat gcaaataaat
    27061 aaatcggcca ttgttcagga ttttcgaaag aatcctttaa gtacgtatca acagcttggt
    27121 aatagttgac ccaatcgatc tctacttctt catcttttgg atttacgcca tggaaagtta
    27181 ctccatctcg ggctccgcct cctccattag aagagaagtt caaaccgcca cctgtcagtt
    27241 cagatcccaa tgcagtaacg acatcaaccg gtgccccttc tggtagagat acttctttta
    27301 cttgtttgtt gctgacctca tacaatttca tggagtcgcg gttcaatccc aataaataat
    27361 aagaatagtt gaactgccca tttttgataa tagccagtaa ataaggaaga tcacttacat
    27421 agtattgatc gtctaccggg atactcaaac gatggatata ggtctggtca gcagttataa
    27481 tgaccgctac actcgtagtt gcactacgcc aaaacgaagg atctcctaac aaattttcaa
    27541 ttttttcttg gaacggagac cagtcatgtt cggaatattt tttctcaaaa cgtttctttg
    27601 cttctttcgc aaaatttttg aatttgatct gatctttttc cacatcttga tgggcgacat
    27661 gcgtattcag catgatcgtg acgaatggtc ctttagcgcc ttctgaagtc aattgtgtca
    27721 ataattcttt atcctttttt gccataaacg tacccctcct aaaaaaatca ttcctttgtt
    27781 tctatctaaa gtctaccaca acactatttt tccatacaat aaaacgtatc taaaaaaata
    27841 aaacggtttc tacggtttta aatttagcta tttttttaag ttatcttcat aatttcctca
    27901 attatttagc cccagtcttc aactattctt catgaaatgc tgataaacta agaaaaagaa
    27961 taaaagaggt ggatcttatg catttaatta tgattttcag tttattaagt attatcagtt
    28021 tatttgcttt cagcgcttcc cgcttattag atgcggaaac acggcctatt cctgtaaaag
    28081 tacgtaaaaa cgaccgctaa acttccataa cgcgcgttct tatcctaaag ttttttcaga
    28141 aacattgaaa ctctctcccc tctctgataa aattttaatt tgtagcgaaa caaattaatt
    28201 acaaggagat cggatatgtc cataaaaaaa acacgtctag tcctattatt ggctagtctc
    28261 attctttgcc ttgcttcttt tctaccagct gttgctgtgc aagctgaaga tacgttcaaa
    28321 gtaaatgcaa aagcagcttt tgctgtagat gcgcaaagcg gtaagattct ttatgatcaa
    28381 gatggagaaa aaaccatggg gatcgcttca atcacaaaaa tcatcggtct ttacatcgtc
    28441 cttgatcaag taaaagaagg aaaactgtca tgggatgata aagtttcgat ttcagattat
    28501 gcagaaaatt tgagtatcac cccagattta tcgaatgttc ctttgcataa agaaaacacc
    28561 tacactgtca aagaattatt cgactctgca atcatccagt cagccaatgc ttcaatggtg
    28621 gccttggcag aaaaaatctc tggcagcgaa gctaaattca ctgaacgaat gaaagaacaa
    28681 ttgaaagatt ggggaatcaa agatgcaaca atcgttaatg catcaggatt gaacaactct
    28741 tatcttggcg aaaaccgacc agaaggcact ggagaaaacg acgaaaatca aatgtctgct
    28801 caagatgtgg ccatcgttgc ccgccatttg atcttggatt tcccagaaat actggatgta
    28861 tcaagtacta cgacccaaat gtttggcgaa aatacgcaat caccagtgga aatggtcaac
    28921 tggaactgga tgctcccagg attcgttaat tacaaggaag gcgtggacgg attaaaaact
    28981 ggtacgactg agcttgcagg tgcttgtttc gttggtacga tcactaaaaa cgatcaacgg
    29041 atcatcactg tcgtattgaa tgcggacggc catgcggaaa acccgagtgc ccgcttcaat
    29101 gaaacagacc gtttgatgga ctactgctat gacaattggt cagaaaaaga gctcggaaaa
    29161 gctaacgcaa gtattcctag tctaaaaacc attgatgtaa aagacggaaa agaatcaaca
    29221 gttcctgttg tgcttaaaag ccctgtaaaa gtatgggtac gaaacgatat ggatactggc
    29281 aaattaacga tcacgccaac acttgacaag aagcaagtca ctgacaatga gatccaagca
    29341 cctatggata aaggtacaaa aatcggtacc gctacgatca ccttggcaga cgataaatta
    29401 ggctatttag aagacaacaa tgcaccatca acagagatca ttacggataa aacagtggaa
    29461 aaagcgaata tattcgtgat tggctggcga cgcgtcgcag aatttttcga caacttgttt
    29521 taattgaaca ataagaaaaa catctttcca tcggaaagat gtttttttgc tttttctagt
    29581 ttaaataaca gcttttttca tctattttcg ttatactgta taagaaaaag gagttgaatt
    29641 tatgaatcta accagagatc tgatcttttt agttctctat cttattgggg tattctctat
    29701 cgtttattgg cgaaaacaga agaaggatcc ttccttgttc ttttacggca gtacgtggac
    29761 atttacggta atcttaactt attttgtcgt gttggaaatt ttttattcga ccttttattt
    29821 tttgattcca ttgttgttct ttagtatctt tgctttttct tatttcacag aaaaacgaag
    29881 gctgctgaat ggtcttttat tcaatgtttt cctcatcagt ttcggcatct acttgtttgt
    29941 cttgctgtat gaaacgcaaa atattttcct tggcggactg atcgccttga tcacgattcc
    30001 attgctactt gtccttttat ttggtattta tggattgatt gtttttcttt tttggaacgg
    30061 ggtcacagtt ttacgtagag aatcgcattc attagctaat cttttaacgt tgatactagc
    30121 catttttctt acactgtttc ttgtttttga ctttttcttg ttaaaatatt tgccgcaatg
    30181 gataaatgct ttgtttttct gcgttcccct gatcttgatc tatctattta tcgtattcta
    30241 caactttttg actgtctcat tcttgtatca gttcaaccgg cctcgataca atcaagactt
    30301 catcgttgtg ttaggcgctg ggttgatcaa tggagaaaca gtttctcctc ttctagccaa
    30361 gcgaatcaat aaggcaattg ctttttatcg ggctcaaagc cgtgctacat taaatccgcc
    30421 catcttattg atgtctggcg ggcaaggagc agacgaaaaa gtaccagagg ccattgcgat
    30481 gaaacaatat gccatggaac aaggaatccc tgaaagagac attcttgtcg aaaccaattc
    30541 gacaaccact ttggagaaca tgctctattc aaaggaaatc atggatcagc aaatgaaagg
    30601 gccataccgc gcgatcttta gttccaacaa ttaccacatt tttagagccg gtctttatgc
    30661 gtggcaagcc aaattgaaag caaatggtat tggtgcaaaa acagctttct actacttgcc
    30721 taatgcgttt ttaagagaat acatcgccat cttgatgatg aacaaaaaaa gacatatgat
    30781 catttgcgga ttgcttttcg caggctccgc attcttatcg ctgattactt tacttttcta
    30841 aaaaaacaag gtgtgacaaa acatatgtca caccttgttt ttttctttca ttctcttaac
    30901 tattggcaaa aagagtatcc cttttttgac cgctacttgc tgggcagaat aaataccgct
    30961 gttgcctgaa cacataaagc tgatcaagca gatcataaag aagtatactg ccgcttgtga
    31021 accgaacaat tcgatcccca tcacaaagca ggcaatcggt gtatttgtcg caccagaaaa
    31081 tactccgata aagcccaatc ctgcaagaaa aggaacagaa acatgaagca aaggcgctag
    31141 tgctgcacca agcgttgcac caatttcaaa caatggtgtc acttctcccc cttgatatcc
    31201 cgcgcctaaa gacaaaactg tgaagaataa cttcccaata aaatcataga catgtgcctg
    31261 tccattaaat gattcttgaa gtaacggaag actcaatccg agataacgtt gtgtttgcaa
    31321 aatcaatgct gctgccacaa ctacagctcc acctatcgta tttcgccaaa caggatgagg
    31381 aatccattgt gcatatcgcg cttttaaaaa gacgatcgaa cggctgaata cccaaccaat
    31441 caaaccaaaa gcaatcccag caacaaaaac tttgaagaac agcaacatac tccattcagg
    31501 aatcacaccc atttggtaat gtagatgaga aacaccatag ctttctgtca tgaaatttgc
    31561 aaacagtgca gcaaagaagc tagggaagat cgcttctgtt cggactttcc cgattgccaa
    31621 cacttctaat ccaaataatg ttccagctaa aggtgtgcca aatacagaac taaaacccgc
    31681 actgattcca ctgataatca agatttcccg ttctgcttta tccaatcgga acaaacgtgc
    31741 tgtattatct gctaacgatc cccccatttg gactgctgtt ccttcacggc caacagaccc
    31801 cccaaataaa tgggtagtta tggttccaaa cagtgtaagt gtaataagcc gcaacgggat
    31861 tttttcttct ccaccatttc cttgatcgat cactaagttg tttccacgac tagaaagacc
    31921 gccgtgatac gcatagagat aagcaaaaag cgcaccacta actggtagta gataaaggag
    31981 ccaaggatgt gatagtcgga tatctgtcac aactgtcagg ctatttaaga aaaaagcaga
    32041 caagctcccc atgaatatac cgagaatcgc tgtgatcacc agccacttca gcatgtacac
    32101 taaaatgcgc attggactcg gtaattgttt ttccataaaa aattcctcct caataaaaaa
    32161 acgcctacta aagaaagggg ctgtccccag actttagtag gcgtcattag ctatctttcg
    32221 ttagcattta aaggcgaaca ccatcaccta ttcacttcca ttaaaagata gcatattttt
    32281 ctgtaaaaaa caataaaatt atcgttcttt ctttacacgt tcagcaaatt catagaaagg
    32341 agccaatttc gttaactgtt gattacattg gtcactatca tgacaaatat aattcccctt
    32401 tttcgtatac gtgccatcag aacctgcttt cgttgtagaa agaaaaagcg acacattcga
    32461 tgttttctga cagattgcac agattccctt atttatcgtt ggtgataaag taccgctaat
    32521 cccttttaat ttttcatctt cgtaatagac catgaatttt ttctgcgtac ctggatcatt
    32581 ccagccgatg tacgtatgtt cttgcaagtc gatttcattc caagctggtt gtttgagttt
    32641 ttttactttt cggaataatt tctcgatttg tggtttgcta ggctgcataa acggctgaac
    32701 gatttgcttc agcttctcca atgctctttc tgcttgcgct tttgtcagtt ttacgtctaa
    32761 aactgtcgtt aaaaatgtat cgatttctgg cagttcgtga tttaatatgt ctcgaatctt
    32821 ttcagctgct agtgcctgaa ctgtttgtac cgtttttgga tcattgacag atgagtacgc
    32881 atttaataac tgttctactt ctctttttat aaaaaaatat tggtatggtt ttattgtttg
    32941 ttccatgatt ttaaagtcct ttcttctaac caaagtgcat actttgtaga aaaaagtgat
    33001 cttctgcaaa gtatgtgtta cctgaagatc ccggactctt ttaaataaga tacgttttgc
    33061 atcttatcat cacccccttt aatgcttatt cttctatgta catgattcat tcgataaata
    33121 aaagtaaacc gtatcttgaa cagatagtca actgcaaaca gaaaaaagga ctgtgacaaa
    33181 agtcgtgtca aagtcccttg tttcgaatga atggtgttca aaagcttgca tctgcggtaa
    33241 taagccgaaa cttcacaaaa atttgagaag caattttcgt aaattccttc ttatttcttg
    33301 aagctgacca cttctgtcac aacctcaata tggtctatta ttggttttac ctgttaaatc
    33361 gaggattctt tcccaaagta acgttgccat ctcttacgca tacttgcaga catgggctga
    33421 gccgcttctt tgactgcgca gtatttgtcc acgaatgtca caatatatcc ttctttatac
    33481 ttaggcggtg cgatcgttgc accccacatg tgcttcaaaa tgatatctcg ctcaagatcc
    33541 gacaaatcgg tgattttttc tgcattcttt acagcaattc ttggatggat atacgcatgt
    33601 gtcccctcgt caaatttcgt cgtacgccaa tcatagtaga acagatcatg caaaagtcca
    33661 gcacgcgctg ttgctttagc attgccaccc catttttttg cgagcagata actatagtaa
    33721 gaaacactga tggaatgctc caaacgagtg gaatgaacat gctgtgtgta attcgctaat
    33781 tttttcactg cttctgtttc taaaagatct tgtacataag acatatattc ttcgtcttca
    33841 cgccattttt ctgtcataat tatcgatctg ccaccttttt gaatttcatt ttcttctgaa
    33901 attgatctaa gtataccacc agtgttcgga ttattctagt cgctctagat aaaatagcta
    33961 aagcttaata gttccttaat cataaagaaa aatgataaag aacgatccct gctgcgactc
    34021 cgacattcaa tgattccgca tttcctttca ttgggatata tacgttctga tcagccgaag
    34081 acaagatttc ctgacttact ccctgacctt cgtttcccat gattatagcg aaatcctctg
    34141 ttttttctac tttgtctaat gcatgtgctt cttcatttaa ttctgtaccg tacaccgtaa
    34201 accctttgcc tttcattaca gggatcactt ctgccaaatc tttttgtaac acaggcaaat
    34261 gataattgct tccctgcatg cttcgcagca cctttgtact ataaatatct gccgttcctt
    34321 tacctaataa aacaccagcc ataccaaacg catctgccgt acggatcatc gttcccacat
    34381 ttccaggatc ctgtacatta tctagtaaaa gccagcctcc tgaaaaatct ggcgtatctt
    34441 cagatgttaa cgtcatcact gctaagatcc cttgcggtgt aggtagatct gacatagcgg
    34501 tcatgacctc atctgaaact agaaaagtag aaatctcttt gtttacagcc agccagtctc
    34561 cccattcttt catacctctc tgtgtcacaa aaagttcttt tatttctgca tcagacgacg
    34621 cagcttcttc gatcagatgg aacccttcca aaagatattc tgccttttct tctctgtatt
    34681 tctttttatg tagttttttt aattctttga ttcttggatt ttttactgat tggatctctt
    34741 tcacattcct cacctcaact gattatatca tggaataggt gcttgagctt gtttcatcct
    34801 aaaaaaatcg gtatcattga tttataaaac aggaaagaaa ggtgacgaac atgcgcaaag
    34861 ttaaaatgaa tgtccaagga cgtgtccagg gcgtgggatt tcgctatatg accaagatgg
    34921 ttgctgatca gttaggcgtg accggaacgg taaaaaacga agacgacggc tcagtcacaa
    34981 tcgaagcaat cggaaatgac gacatcatcc aaaaatttat cgaagaagtc aagaagtctc
    35041 cgagcccaag tggacgagtg cagtatgtgg atgtccaaga agatccgatg attgaggaac
    35101 gaaagaaatt tgatgtggtg ggataaggtt gtttttgaag cgctttgcct cgagtattaa
    35161 ggagaaacat tttccaaata gcttctcata ttttgaaatg taatgactta ataccgagag
    35221 gcagctgata aaacaccgtc aataaggttg tgaaaaagct ggtctgcatc aagcattaag
    35281 gactggttgt gaaaaatagc tctccatatt tttcaacagg ctggacttaa tgccgtagat
    35341 gcaagctttt gaacaccgtc gataaggttg cgaaaaagct gatctgcatc aagcattaag
    35401 gactagttgt gaaaaagtcg cttagttttg agtattaagg aaaattttgt gaaaatggct
    35461 ttccacattt ttgcataaat ttgacttaat accaagaaac tgacttttga acatcgtcga
    35521 taaggttgtt tttgaggcac tttgcctcaa gtattaaaga caggtagtaa aaaagctgat
    35581 ctataacttg caataaattt gcttaaccca tattttccag acagaacaaa aaagttttta
    35641 gttttttaaa taagaaagaa acacttggaa tcactctttt ctttctaagt atttctttct
    35701 tgattttttg tcttttttca aaatttttcg ctacgaaaaa gaacgaatat ttatatgaaa
    35761 tttctatgaa gttgattgaa ttccatgcgc ttttttagta tagttaagtt tgtgtaaaaa
    35821 ttatagaaga ggaagtattc tatgaataaa tggaaaaact ggttattggg atccggactt
    35881 gtcagtatcc tgctcttttt atctggctgt gtgcggatgg attcaaacgg aaaccctgac
    35941 acttcaggaa tcgtttatcg agtactcgtc catcctatgg gccaagcgat tacatatcta
    36001 gttgagaatt tcaattggtc ttacggctgg gcagttattg caatgactgt gatcgttcgt
    36061 atcatcatct tgccactagg tatcagtcaa tcgaaaaaaa caatgatcca atctgaaaaa
    36121 atgcaagcgt taaaaccaca agttgaagca gcacaacaaa agctaaaagc tgcaacaaca
    36181 cgtgaagaac aaatggcagc acaagcagaa atgcagcaag tatatcgcga aaatggattg
    36241 agtatgaccg gcggaatcgg ctgtctgcct ctattgatcc aaatgccgat cttctctgcc
    36301 ttgtatttta cggctcgcta cacagaaggt atccgtgaat catcttttta cggcatcgat
    36361 ctaggctcac caagtatggt gcttgtggcc atcgcagggg tcgcttatct gcttcaagga
    36421 tatatttcaa caatcggtat tcctgaagaa cagaaaaaga cgatgcgtac gatgctgatc
    36481 gtctctcctg ctatgatcgt cttcatgtcg atcagtgcgc cagccggtgt tacactttac
    36541 tgggtagtcg gtggtgtgtt cagctgtctg caaacattca tcacaaacgt tataatgaaa
    36601 ccgcgtttga aagcacaagt ggcagaagag ttgaaacaaa acccgccaaa acaagtcgtt
    36661 actccaagaa aagacgtgac agaatcagca aagccagctg acaacaaaca agcaacaaaa
    36721 caaatcaaac aaccaaaaaa cagtacaaac aacaaaggcc gcaacgcagg aaagcagcag
    36781 aagcggaaat aaaaatatat gacaaaaaac tgtagacaaa taaaaaaatt tctttgttct
    36841 acagtttttt tgt
//
LOCUS       DAFEKH010000027        36569 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.028, whole genome shotgun sequence.
ACCESSION   DAFEKH010000027
VERSION     DAFEKH010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36569
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.028"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(26..1522)
                     /gene="lysS"
                     /locus_tag="LP386_001486"
     CDS             complement(26..1522)
                     /gene="lysS"
                     /locus_tag="LP386_001486"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HBL1918726.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="LP386_001487"
     CDS             complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="LP386_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HBL1918727.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="LP386_001488"
     CDS             complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="LP386_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HBL1918728.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3742..5853)
                     /gene="ftsH"
                     /locus_tag="LP386_001489"
     CDS             complement(3742..5853)
                     /gene="ftsH"
                     /locus_tag="LP386_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBL1918729.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="LP386_001490"
     CDS             complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="LP386_001490"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBL1918730.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="LP386_001491"
     CDS             complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="LP386_001491"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HBL1918731.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8053..8523)
                     /locus_tag="LP386_001492"
     CDS             complement(8053..8523)
                     /locus_tag="LP386_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HBL1918732.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8569..8994)
                     /locus_tag="LP386_001493"
     CDS             complement(8569..8994)
                     /locus_tag="LP386_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HBL1918733.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9061..9330)
                     /locus_tag="LP386_001494"
     CDS             complement(9061..9330)
                     /locus_tag="LP386_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HBL1918734.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9341..10936)
                     /locus_tag="LP386_001495"
     CDS             complement(9341..10936)
                     /locus_tag="LP386_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBL1918735.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="LP386_001496"
     CDS             complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="LP386_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HBL1918736.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14489..15049)
                     /locus_tag="LP386_001497"
     CDS             complement(14489..15049)
                     /locus_tag="LP386_001497"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBL1918737.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15402..16376
                     /locus_tag="LP386_001498"
     CDS             15402..16376
                     /locus_tag="LP386_001498"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBL1918738.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16546..17946
                     /locus_tag="LP386_001499"
     CDS             16546..17946
                     /locus_tag="LP386_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HBL1918739.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18024..18746)
                     /locus_tag="LP386_001500"
     CDS             complement(18024..18746)
                     /locus_tag="LP386_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1918740.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18825..19331)
                     /locus_tag="LP386_001501"
     CDS             complement(18825..19331)
                     /locus_tag="LP386_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBL1918741.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19454..21253
                     /locus_tag="LP386_001502"
     CDS             19454..21253
                     /locus_tag="LP386_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HBL1918742.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21321..22895)
                     /locus_tag="LP386_001503"
     CDS             complement(21321..22895)
                     /locus_tag="LP386_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBL1918743.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23150..23659)
                     /gene="mreD"
                     /locus_tag="LP386_001504"
     CDS             complement(23150..23659)
                     /gene="mreD"
                     /locus_tag="LP386_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HBL1918744.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23663..24517)
                     /gene="mreC"
                     /locus_tag="LP386_001505"
     CDS             complement(23663..24517)
                     /gene="mreC"
                     /locus_tag="LP386_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HBL1918745.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24672..25310)
                     /locus_tag="LP386_001506"
     CDS             complement(24672..25310)
                     /locus_tag="LP386_001506"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HBL1918746.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25311..25961)
                     /locus_tag="LP386_001507"
     CDS             complement(25311..25961)
                     /locus_tag="LP386_001507"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBL1918747.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(25974..26873)
                     /gene="rsgA"
                     /locus_tag="LP386_001508"
     CDS             complement(25974..26873)
                     /gene="rsgA"
                     /locus_tag="LP386_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBL1918748.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27038..29107)
                     /gene="pknB"
                     /locus_tag="LP386_001509"
     CDS             complement(27038..29107)
                     /gene="pknB"
                     /locus_tag="LP386_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HBL1918749.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29104..29844)
                     /locus_tag="LP386_001510"
     CDS             complement(29104..29844)
                     /locus_tag="LP386_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HBL1918750.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(29857..31215)
                     /gene="rsmB"
                     /locus_tag="LP386_001511"
     CDS             complement(29857..31215)
                     /gene="rsmB"
                     /locus_tag="LP386_001511"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HBL1918751.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31215..32153)
                     /locus_tag="LP386_001512"
     CDS             complement(31215..32153)
                     /locus_tag="LP386_001512"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HBL1918752.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32146..32637)
                     /gene="def"
                     /locus_tag="LP386_001513"
     CDS             complement(32146..32637)
                     /gene="def"
                     /locus_tag="LP386_001513"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBL1918753.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32652..35060)
                     /gene="priA"
                     /locus_tag="LP386_001514"
     CDS             complement(32652..35060)
                     /gene="priA"
                     /locus_tag="LP386_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HBL1918754.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35313..35618)
                     /locus_tag="LP386_001515"
     CDS             complement(35313..35618)
                     /locus_tag="LP386_001515"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBL1918755.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35623..36237)
                     /gene="gmk"
                     /locus_tag="LP386_001516"
     CDS             complement(35623..36237)
                     /gene="gmk"
                     /locus_tag="LP386_001516"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBL1918756.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYINKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
BASE COUNT         9886 a         7989 c         6706 g        11988 t
ORIGIN      
        1 aattccttag acagctttta ttcgattatc tcattgttgg gaatagcaaa acatcccgaa
       61 ttgattgtgc atcagttagc aacattacta atctgtcgat cccgatgcct agaccaccag
      121 ttggcggcat accgtattct aaggcttcca agaagtcttc gtctacaccg tgagcttcgt
      181 catttcctag ttcacgttct ttttcttgcg cttcgaatct ttctctttga tcaattggat
      241 cgttcagttc tgtaaaggca ttagcaaatt cgcgccccac tatgaatagt tcgaatcgat
      301 ctgtgaatcg aggatcttct ggatttttct tcgctaaagg cgaaacttcg actggatgtc
      361 cgtatacaaa cgtcggttgt gtcaatgttt cttcaacaaa tgtttcaaag aattcattga
      421 taacatgtcc gacacccata gcttcggtta cttctacatt gtgtttttcg gctaaagcta
      481 atgcttcttc caatgtcatt tcttgccaga agtctacacc agtttgttct ttgattgcat
      541 ctaccatatg gatgcgttta aagtcacttt ctaagtcgac agcttgtcca tcatatgtga
      601 tttttgctgt tcctagtact ttttcagctg cgttacggat aataccttct gtcagattca
      661 ttacatcatt gaaatcagta tatgctgtgt atgcttctaa catcgtaaat tctggattat
      721 gtgtagtatc aattccttca ttacggaaaa cgcggccgat ttcataaact ttttccattc
      781 cgccaacaat tagtcgtttt aaatgaagtt ctagcgcaat acgcaaatat aaatcaatgt
      841 ccagtgcatt atgatgcgtg ataaatgggc gtgcggcagc tccacctgcc tcattgtgca
      901 atactggtgt ttctacttca atatagccat tgccatctaa atagcgacgg atttcgctga
      961 taatttggct tcgtttcata aatcggtcaa agctttcgcg attactgatt aaatccaagt
     1021 agcgttgtct gtagcgttgt tcaatattcg ttaagccatg gtatttatct ggcagtggac
     1081 gaagtgcttt tgacaaaatc gtgatttctg aagctttgat agaaacttcg cctgtgtctg
     1141 ttttcatgat ttgtccagtt acaccaaaga aatctccaag gtctgcatgt ttgaatactt
     1201 cataggcctc atcacctact tggtcttttc ttacataaat ttgaatttgg ccttcacgat
     1261 cttgtagatg cgcaaatcca gttttccctt ttcctcggcg agtcatcata cgaccagcta
     1321 cactagcggt caatcccatt tctgctagtt cttcttttgt tcttggatca aatagttcat
     1381 gcaattcttc tgagttgtgc gtgcgttcaa atcgttttcc aaatggatcg attccatctt
     1441 cacgcaattg ttccattttt tgacgacgta caagcatttg atcatttaaa tcttctactt
     1501 gatgttgttg ttcctgtgtc acaaaagttc ctccattctc atgttaatct ctttcctata
     1561 atgccaatga aacacaaaaa aagcaagccg aacttggaat ttcggcttga aaattcacga
     1621 aaaacttaga aatcacaacg tttgtttcaa tagtactttt tccgcttttt ctacaaattg
     1681 atccagcagg tcattgattt cttgctgttt ttctgtctga ttgattgcta ctttcacttt
     1741 cgctgctcga ggaatccctt ttaaataata agccgcatgt gttctgaatt ctctacaagc
     1801 tactttttct cctttgagat ctgctaagcg ttgtaaatga agtttagctg tagcaatttt
     1861 ttcggctggt gttggttcag gaatcagttc tcctgtttcg agataatgct gtgtgcggtg
     1921 aatcatccat ggattgccca gcgctgcacg accaatcatc acaccgtctg caccgacata
     1981 gtcaagcatc cattttgcat cttctggcgt tttgacatcc ccgttcccca taaatgggat
     2041 cgtcaaatgt tttttcactt ctttcaatac ttcccagtcc gcttttcctt catacatctg
     2101 aacccgtgta cgtccatgca tagcgatggc acttgctcca gctgattgtg ctgctaatgc
     2161 attttctaca gcaaagacgt gctcttcatc ccaaccaata cgcatcttga ttgttactgg
     2221 gatatttact gctgaagaaa cagcttggac catttcgtat actttctcag gatctaaaag
     2281 ccattttgct cctgcttctg ctttgattac tttatttact ggacagccca tattgatatc
     2341 tattatatcg gcagctgtgt tttcttcgac aaattgagca gcttcaacta gactatcttt
     2401 atttccgcca aatatctgta aacttaatgg atgttctgtt tcttcaatgt ggagcatctc
     2461 taaagttttt ttgtttctga aatgaatacc ttggtcactg atcatttcac atacgactaa
     2521 gcccgcacca aattctttga cagtgactcg aaatgctgaa tttgttattc cagccatcgg
     2581 tgcaacaacg acacgattag ggatttccac attgccaatt ttccatgtgt gttccactta
     2641 aatccctcct aaggcttctt tcttcaatcc atctaattct tcttcgctat acttgtattt
     2701 gttattacag aaagaacaaa ccgcttctgc accgtgatct tcgtctatca ttgcttggat
     2761 ttcttctgca cctaacgcga taattgcttc tgcaaatttt tcttttgaac agtcacattt
     2821 gaattgaaca ggcatttttt ccaaaatgtt caattcttct gtaccaagca atcctttcaa
     2881 tatttcttct ggtgtctgtc cttcatctaa gagggtagag attcttggtg tcgtttttaa
     2941 ttgttcttcg atcttgctga ttgtttcttc atcggcacct ggcatgattt ggatcatgaa
     3001 tcctcccgcc gtcttgatgc tgtcgtcagt attgaccaat acactcagtc caacagctga
     3061 agggatttgt tctgagatag caagatagta agtaaaatct tcagcgattt ctccagaaac
     3121 aatcggcgtt tgcccagaaa aaggttcttt taatcctaag tcttttgtga cagtaaacat
     3181 tccttgtgtt ccaactgctc cccgcacatc gattttacct tcactattta gaggaagact
     3241 gagatgcgga tttttgatgt aacctttcac atctcccttt ccatttgcat ctactacaat
     3301 tcctgttgct ggaccatcgc cttggattcg aacagttagt ttgtcttctc ctttgagcgt
     3361 cgcaccaagt agcagactac cgaccaatgt ccgtcccaaa gcagctgagg aggtgtgcca
     3421 agtatcatga cgtctttgtg cctccgctac ggtatttgtt gcttgaacgg cgtatgctcg
     3481 gacgaatccg tcgtgagcaa gtgccttaac caaataatct ttcatttgtt atgtactcct
     3541 ttttccgttt ttaaactcat agtgaatcat actagcaact actgcttttt tcaactttgg
     3601 aatgcttctt ttaaaaataa ttcagaatca tctagaaaac aggacatcac cctatttaca
     3661 acttaaataa agaaatctcc cgaaaaccgg tttttgttcc ggttttcggg agtcatatca
     3721 gatcaattga cctatatttt tttatttgta ttgatcgtct gaatgattat cttctgattg
     3781 ttgagaatct gaatcatgtt ctgctttatt ttcctcattc agttcatgtt ttgcttcttc
     3841 aaaatcacgt ttttcttccg cttgtttttc agcgtctttt tcttccaaag cacgttttgc
     3901 ttcttcaaaa gttttcgctt ctttttcgct tggataatca tttgactcag taccttcagg
     3961 catcacaccg tgttcaaaca atgacttgat tgctttggca tccaatgttt cgaattccaa
     4021 aagtttttca gcaatcagtt tatgctgtgc acgatgagct tcgatgattt ctcgagcttt
     4081 atcatgagct tccatcaaga tttttcgtac ttcttgatca atctcgaaag cgacttgttc
     4141 cgagtaagct tttgtttgac catagtcgcg gccaacaaac acttgatggt ttccttcata
     4201 ttgaacagga cctaaacgat cactcattcc atattctgtt accatgcttc gtgctagagc
     4261 tgtcgcttgc tcaaagtcat tggaagcacc agttgattgg acattgaaga tgatttcttc
     4321 agctgtacgt ccaccaagta agcctacgat ttgttcaaac atatcttctt tcgtcatcaa
     4381 gaactgatct tcttttggta aagcgatcat atatccgccg gcgcgtccgc gagggatgat
     4441 cgttactttg tggacgaccc gagcgcgact caatactaat ccgacaatcg tatgaccagc
     4501 ttcgtgataa gcaaccattt cgcgttcttt tttgctgatt acgcgatctt ttttagctgg
     4561 acctgcaatc acgcgatctt ccgcttcatc gatatcagaa gcatcgattt tctttttatt
     4621 tcttctagca gctactaacg ctgcttcatt caagacattt tctaaatctg ctccggcaaa
     4681 acctggtgtc tgttgagcca caactttcaa gtcaacgtca tctgccatcg gtttattccg
     4741 tgcatggact cgcaagattg cttcacgacc ttttacatct ggacgtccaa ctaaaatctg
     4801 gcggtcaaaa cggcctggac gtagtaacgc tgggtctagt acatcagaac ggttggttgc
     4861 agcaatgacg attactcctt catttccgtc gaagccatcc atttctacaa gcaattggtt
     4921 caatgtttgt tcgcgttcat catgtccgcc gcccataccg gcaccacgtt gacgacctac
     4981 cgcatcaatt tcatcaatga aaatgatagc tggtgcgttt ttcttcgctg tttcaaacaa
     5041 atcacgaaca cgacttgctc caacaccgac aaacatttct acgaaatcag aacccgagat
     5101 cgagtaaaac ggtactccag cttctccggc aacagctttt gctaataagg ttttacctgt
     5161 tcctggaggt ccttctaaaa gtacacctgc cgggatacgg gcacctaatt caacaaatcg
     5221 gcgaggatct ttcagaaatt caacaacttc aactagttct tgtttttctt cttccgcacc
     5281 cgctacatca gaaaaacgta cgcgattagc ttttttgtct gcttctttgg cttttgattt
     5341 accaaagttc atgacacggc cgccaccgcc accgccgccg ccttgttgtc ccatcatcat
     5401 gtaaaagaaa aagatgatga ttacgattgg caagaagcta agcaataggg aaacccatat
     5461 accgctgctt gattcttctt ttactgttgt agcaactttg ttttcttttg ccagttctgt
     5521 tacttggctc aatgttgtat catttggcaa aatgattgtt gtgaaatggg tagtagtcgt
     5581 atctgttgaa cctaagatag ctaacccacc gctgttagcg acggtctgct gttctttgta
     5641 ttcaccagtg atcttatata caccatttgc aggctgcact tcaaattctt tgatcttgcc
     5701 tgcttgtagt tgttctgtga attttgagta ctcgatatct gacgatcgct ggccgttatt
     5761 accaaaaatg aaataaacga ccattaccat cgctaagatt acgaggacat aatacaaggc
     5821 atttttcatc atgccgttgt tctttttgtt catagttgcc ctccctaagc gtcaatttaa
     5881 tttaacagtt ttttatcaat cctgaccatt ctattgtacc ataatttaat tgagatacag
     5941 cattaatttg attgataaac actaggtttc aatacaccga tgtacggaag gttacgatat
     6001 gcttctgcat aatccaagcc ataaccgacc acaaattcat ttggtacgtt gaagccaaca
     6061 taatctgctt cgatatttac tactcttcct tcaggtttgt caagtagtgt aacaattttg
     6121 actgattttg ctttgcggta tttgaaaaga tccactaaat aagcaagtgt tcttccgctg
     6181 tcaatgatat cttcaacgat caacagatcg cgaccttcta cattcgtatc taagtctttg
     6241 acgattttta cttcccctga cgagactgtt gcattcccgt agcttgaaac atccatgaaa
     6301 tccaattcca aatacgtatc gatagaacga acgatatctg ccatgaatgg taccgctcct
     6361 tttaagacac ctactactag gggattggtg ttttggtaaa tttctgttaa ctctttgcct
     6421 agttctttgc aacgaacttg tatctcttct tgtgagatca aaattctctc aatatccttt
     6481 tccaacatca ggttctcctt ccaattgctt ctttttgata tttgtaaaga agtatgtagt
     6541 gtattttatc agtttcttca cgaatactca aatatgaaaa ggcaaaaggt atcaagctat
     6601 atatatttct tttggcatct gtaatgatcc aagcatgctg cctttgtgaa ttaggtactt
     6661 tctgatcgat aaaatatcta gatacttttt ttgtgagatt ctctgttaat ttaatgcggt
     6721 ctcctgcttt tcttttttcg acatacagtt gcacatcagc aggaatccaa atgtcatgag
     6781 aaaatagaga ccatgaatct gttgctttga tgtcccctgc attttcaggt ttgaccagac
     6841 caatccattc tgtttcattc aaatatattc cttgttctgg aatcagcaac aagcgctggt
     6901 cttctgtctg gctagttgct tgtttttctt ttttagagag tacaacaaaa tgatactctc
     6961 ttttcagtat ccaattattg ccaatactga gttgccattg gctttttttc tgttgccact
     7021 ggtctaaaat cgactccatt tgttgttctt tcaaaataat tcctgttttt gagaatgctt
     7081 tgtcgaaaaa ggagtaaaaa aaatagtatc gttcagcatc tgtcatttct tcaatcattt
     7141 ctgcagaaaa tcgaaattgt tcctcccact gttcgacttc cttttcgatc aactgtccca
     7201 tatatttttg aatgacttgg tctgcccatt ggatctgttg cgaaaattgc tggaaatgtc
     7261 tcaacgcctg tgtattttct tgtttcaatt gaggaactac caaatgacga agccgatttc
     7321 tctggatatc taacaattgg tttgtctgat cctcaaagta aacaagctgc gattccgctg
     7381 cataagtata taggtcttct ttgctaaaac tcagcaacgg acgaatcagt ctgcccgtag
     7441 caaatggttg tacttctttg attccagaaa aagtatttaa ctgtccccca cgaacgattt
     7501 tcattaacac cgtctcgatt tgatcatctc cgtgatgagc agtcatcaac gtgtcatatt
     7561 gtccttcttc catcacgcga gtgaattctt gataacgaaa gttacgagct tctgtttcta
     7621 tggcggattt ggctggatct tcccaaatac ttacatataa agggagattc ttctcttcac
     7681 aatatgagcg aagataggca gcttcttctg ctgattcttc tcttaattgg tgattgatgt
     7741 ggacgatacc taaagaaaaa ccgatttggc gttgcacttg taaaagtaaa tggagcaaaa
     7801 ccatcgaatc aacaccacct gataccgctg ctaaaattct cgatccttgt tgccagaatc
     7861 cttgttcatt cccgtgccga ataaatgact gctgtaatag cggtgctttt ttcccgcctt
     7921 tttcaacgtt catcctttcc acaccctttc ttcctaaaaa aaagagagcg ggaaaacgtc
     7981 taaaacgaca attaacctgc cctctgttga tactatgacc caaatagtcg cactatcatt
     8041 atttgcggct ttttagctgc gacgtccgcc acggccaccg cgctttcctt ctgtgtttcg
     8101 cttcaatgaa gataagcggt catcgctatc tttcaaaaat gaactcatca atgaatcgaa
     8161 gtcttctttt tgagctgaag gttgactgcg agaaaaagat tttttctgtg ctggacgatt
     8221 tcggttgtca cggggatctt tttgttgata ttttttagga cggctttctt ctccagattc
     8281 agcaggttgt tcctgcgctt tccggataga tagtccgatt tttccatcat catttactga
     8341 aataacttta actgttactt catctcctac acttaaaaca tcatggatgt cttttacata
     8401 gccatttgac acttcgctaa tatgaactag acccgttttt ccagcaccta gatcaataaa
     8461 cgcaccaaaa tttgtgattc ctgatacttt tccttgcagt tttgctccta cctcgattga
     8521 cataaaaaaa atgttcctcc taattatttc ccttttttat attcctgctt attttgcagt
     8581 tgtagaacta gttgattgat ctgtttcatt tgtcgagctg tctgtatttg attctaatat
     8641 aggataaact ttttcaccgt cttttgagta aaagaatttg cttctggcaa gtttagctac
     8701 atactcatca tctttcagca atgaaacatc ttggtgcagc tgatcaacgt ctgcgttgac
     8761 ttctttcatt tcagtatttg cttcgactct caattcgttc aattgatgca tcctttgcat
     8821 gtcatggaaa atctgcacac ctattatcgc gaaaatgacc aaagcaccaa caaaaattgc
     8881 agccagtctg cgtcttcgaa aaatcagttg acgttgttgt tgctgaaatt cagcatactt
     8941 tttctttgca tattccgtat ctagcgcagc gattttattg ctttttttcg tcacttggat
     9001 tcgctccaat ctttttgatt gtctttttca ttataccaat atcgtgaaag cttgtctaat
     9061 ctatttctct agtgtttctg tgcgattttc agaaataatt tcgtacattt tttgtgcatc
     9121 ttcttttttg gttgattcat gtaattccgt aattttcact tccaacgttt tgttgccaaa
     9181 ctggactttc aaaatatcgc ctactttgac atcactggaa gatttcgcca atttaccgtt
     9241 gatttgaatt cttcctttat cagctacttc ttttgctact gatcgtcttt tgatgattcg
     9301 ggaaattttt aaaaatttat ctaatcgcat atcttattcc tcacttttta atttttttat
     9361 ttaatcgcag gattttctta ccaaaaggca acattagcca ttctcgtact gtaaacagac
     9421 gaagacgaat cactgcataa atgaacacag aagccccgat cccaactcct atcacgctga
     9481 caaaaaaagc agtggaacga tgagttacag gaccaaatac tatattcaat acaccataat
     9541 acagcagcag tactactgtc atacaaagaa ggctgaacat caacttccgt ccaaaatgcc
     9601 gttctttcca aaaagcattt agctcttttg tttcaattcg aacaaaatac caaagcgtca
     9661 cacctaatcc taaaagggta gacaggcttg cacctgctgt tcctaataaa ccggtcagaa
     9721 aagaagtagt caatcctttt accaatagtc cccatcctgc gccttttaaa gaagggcgaa
     9781 acgagttctt gctttgagca atactttgat aagcttggat gactgcagtg aaagcaatgg
     9841 aaaaaacaaa taatacaagc gctgcatttc ccgcataatc tttaaacaac gcataattga
     9901 tataagggag cagcaaggct aatcccaaag acgcagctaa tgctaaagcg gtcgtcaatc
     9961 taagatagat tttggctgtc tgtaaaaact gacgatagat ccggttggtc aaatgacgag
    10021 tcaacgcagg caggaatgtc gcacttaatg cagtggcaat cactaaacct aattgtacta
    10081 aaggctgacc tcgatcatag accccttttg ctatcttcgc accgtattct gacagtccgt
    10141 aaacttccaa agcatttttt acaaagaaag agtcgatcag ctggaaaaag ataagcaatc
    10201 cactataaat cgaaaccagt ccgccttcta ccagaaaacg ccggatcaag ggctttgacg
    10261 gctgtttgaa caatggaaac cgtcggaagc ttaacgctcc tccatgaatc ttttgttcat
    10321 agtagtgaag gatcccatat gcgcataaac cgccaaaaac agctccactc attgctgccg
    10381 tccctgtttg gtacaccgtc catccaagct ttctaaaagc aaacgcacta cagacaatca
    10441 caaaaacacg aacgaactgc tcaactactt gagaaacagc agttggttcc atcaagaatc
    10501 ttccttggaa attccctcga taaaaagata gaccaggcat cagcaaaaag gtaaaggaaa
    10561 ctacttggat cagcggtttc aattgtatgt ctcccatcat ccaagcaatc cagctgctaa
    10621 atgcaaagac aaacaaccac aaaaagacac ctgtccaaaa tactaaggga taaagatttt
    10681 gcaaagcttg ctttcgctcg aaaggattct ttctttctgc aacgtacttt gatatgaact
    10741 gcggaagacc ggataaagct aaagtcattg ctatcccata aattggataa acttgctgat
    10801 aaacataaaa accttcgtcg ccgactaagt tttggagggg aattcggtaa agggcactta
    10861 atacttttgc tatgaaagaa gcaatcgtca atacaaatgc tccttgcatg acgcgccgca
    10921 tttctttatg atccaaatca ttgctccttc ctacgctgac agatattttt gctcacgcaa
    10981 cgctttgaca aacttttgga tttcctgaag ccatactgct tcttccattt ggttggggat
    11041 cgtcaagcgt atcaccatct gttctttttc aacgcctaga ctggctttta gttttgtcgc
    11101 tgtcagtgct tcgaataact gttccacact atagcgtttt gttccaactt tacttagagt
    11161 aaagactata tgcgcctcct gtttccttat cgtttctagg agcgctcgat cgccatccat
    11221 tttgatctgc ccaattgtca agagatgtgc tacttcttct ggatattctc caaaacggtc
    11281 gagcagatca tcttctagtt catctagcat ttcttgcgaa tcaagttcac gaattcgttt
    11341 atagatctcg attttctgcc gttgatctgc cacgtatgtt tcaggtagat acgcatcgac
    11401 accgaggtcg atctcaacag tggtcttctc cacttgacta ttctttcctt gtttacgaga
    11461 aacagcttcg cttagcattt gagaatacat atcgaaaccg actgcatcaa taaatccatg
    11521 ctgctgagca cctaagagat tacctgcacc gcgaatggaa agatcccgca tcgcaatctt
    11581 gaatccagat cccagttctg taaaatcttt gattgcctga agacgttttt cactgacttc
    11641 gttaaggatc ttctgctgct catacataaa gtaagcatat gcgacacggc tgcttcttcc
    11701 tacccgccct cgcaattggt ataacgtgga taatcccata taatcagcgt tctcaacgaa
    11761 caacgtattt gcgttcggga tatctactcc tgtttcaatg atggttgtag tgacaagaac
    11821 atcatattga ccttcaataa attcaaaaag cgtattttct aattgcgcct ctgtcatttg
    11881 cccatgagca taaccgatcc gtgcttccgg aacgagttct tggatttctt ctactttttg
    11941 ttcgatcgtt tctacccgat tatataaata gaatacttgt ccacctcgtc ccatttctcg
    12001 atggattgct tcgcgaatag ccccaggatt tttttccata acatacgttt ggatcggata
    12061 acgattcgca ggcggtgttt cgattactga aagatcccgc acgcctaaca tcgacatatg
    12121 caaagttctc ggaatcggtg ttgcagtcag agtcaaaaca tccacttgtg cacgtaactg
    12181 tttcaatcgt tccttatgtt ttacaccaaa acgttgttct tcgtcaatga tcagtagacc
    12241 caaatcgcta aattcaatat cttttgacaa aattcggtgg gttcctacaa caatatcaac
    12301 ttgacctgta cgcagttgtt cgatggtttc tttttgttgc tttcttgttc tgaaacgact
    12361 taatagcccg atatttacgg ggaaaccttc aaatctttcc agcatcgttt catagtgctg
    12421 ctgtgccaag atcgttgttg gaactaaaaa ggctacttgt ttgctttcct ttatcgcttt
    12481 aaaggccgct cgaagcgcta cttctgtttt cccataacca acatcaccta cgagtagtcg
    12541 atccattggt ttttcttttt ccatatcccg tttgatctcc gctgcacttc tcaactggtc
    12601 atcagtttca gagtagggga aggcattttc gaattctttt tggtaggcgt catcaggtcc
    12661 aaaagcatat cctttttctg actctcttgc ggcatataat ttgattagat cgtcagcgat
    12721 atcctcgatt tttgaagaga cttttcgctt ggttttcgtc cattcacttc cgcctagctt
    12781 attgatgcga ggcgctttgg cttcagaggc gacatatttt tggatcagat tcagttgagt
    12841 aacaggaata aacagtttgt cgtcgttttg atacaaaata gtcatatagt cttggtgaac
    12901 gccatctact tctagcgttt ccatcccaat gtatttcccg ataccatgat tggcatggac
    12961 aacgtaatct cctgctttta actcattata gcttttcaat cgctctgcgt ttgttactgt
    13021 ttgacgtctc gtttgttttt tcgtcgtttt ttggaaaatt tctttttctg tgatagctac
    13081 tattttttct tgaggaagtt caaaaccagc ctgcaaagct ccttcaacta attgtacctg
    13141 tcctctgatc aatgcatttt tttctgtttc tactactaat atgtcttcat ctcgaagcat
    13201 ttgttctgct ttgcgtattc tgtcctttgt cggaataaag atcacaacag tctgtttttg
    13261 cttgcgccaa cggtccattt ctgttttcag caatggcatt tgtccgaaga actgttgcat
    13321 cgtccgatat tgaaaattat ggattgcttg gaaacgaaga tttcccatcc ctttttggaa
    13381 gagtgagaaa aaggttgtgg tgaacttttc cttctgcacg attttttgta tatctgctga
    13441 aaatgtctgc tcagaaaaca cccgcaattc gctgattttt tgagtctgcc attctgccgc
    13501 ttccctttcg atttcccgat ttgtttccat gattcgctga taatcatcaa cgactagtaa
    13561 actatttgaa gggaaataat ccaagatcgt cacagattct tggtaaagaa gatctgagta
    13621 gaattttgct tcttctgtcg ggacacctgc ttgccagctt gaagtcagct gaccgaagta
    13681 atcttgcaaa aactcgcggt ctgcttcttc tgtggtcgca gcaagccgtt tttctagcat
    13741 tttttgcatt tgctctattc catgttctag atcctctggt ccgtagactt gttcactcgt
    13801 tggggaaacc cagatttctt ccgttttttc gattgagcgt tgtgtttctg cttcaaaata
    13861 ccgcatagaa tctatctcta catcaaatag ttctacacga acaggatagg ttgtcgttaa
    13921 cgggtaaata tcgataatgc ttcctcgaat actgaattct cccggttttg cgaccatctc
    13981 ttctcgtaca tagcccatca aagtcaattg gcgaggaaga ttttccacgt ctatctcatc
    14041 accaatatgc caattcaatt gcgcctgtag ccaagttttc ttattcggca gtcgtttgtg
    14101 caaagatgcg actggcaaca aatagatacc tgcttttttt tcttgaagtg cgttaagcgt
    14161 tgcaactctc tcgcctcgcg cttctggaga agaaaaggcc atttcagcag aaagcacttc
    14221 atccactgga aataaatgga tctgatcttg cggaatcaca tgttgcagat cttctgctaa
    14281 ctgattcgca taatacaaat ttggcatcag aataatcatg tttttatttg ttttcttaaa
    14341 cgctcgagca aatagaagtg ttttcgctga gcccgctaat cctgtgatta gttgtctagg
    14401 cattttttct tctaaattgc tgacccattc ttttacttgc ggatcttttc cgactaattg
    14461 aataatatcc attccttttc ctccttcctc aattgaatcg attcatcgca tccacgaacg
    14521 aatgcccttc tatgagatat tcgactgctt taacagattg acacatgctt tcttctatca
    14581 aaggctgatt ttctttgctg aaaggactaa gcacatgctg gactactgtt tttttccctt
    14641 ctggcctgcc gattcccacc ttgattcgat caaagacatt cgtattcaaa tgggaaataa
    14701 tacttttgat accgttatgc ccgccggcac ttcccttttg acggagccgg atttttccca
    14761 ctgccagatc caaatcatcg tagattacga ctaattcctc tggataaatc ccaaaataag
    14821 tcattagtgg gccgactgca cgaccagatt cattcatgaa tgtttgtggt ttgactaaaa
    14881 ggatcttttc tccattatga aaaaattcgg caacttctgc ttcgaacgga ttttttttga
    14941 aagtagcttg atgctcgcgt gcaattttat ccacgaccat aaagccgata ttgtgttttg
    15001 tatattggta tttggtacct gggtttccta acccgacgat cattttcatt tttgttttcc
    15061 acctaattct aaaaagcagc acaaaaggct ggactgctaa ttagcggtcc agtccatcga
    15121 gcttttttct tttttatact tgtcaatgca tagtataaca caaaacaagg cgtttcggct
    15181 aaaagagaat cgttaataaa tgataaagaa attaaaaatt tcttcaaagt ttaatgaaat
    15241 aattgatata taaaaatagt gaaataacgc acatgtaagc ttttacatat aatacaacct
    15301 tgttatctgt tatattttat agccaaatag cgtgacatgg ggcttgagaa atgttagcat
    15361 aagcatggga aaaaacaaat caatggaagg attgatacta aatgactgca gctgcagaaa
    15421 aaaaagatca tcaaaaagtt attcttgttg gagacggcgc cgtaggttct agctatgcct
    15481 ttgctctagt tactcaaaat atcgctcaag aagtaggtat tgtggatatc aatactgcta
    15541 aaactgaagg agacgcaatt gacttgtctc acgctttggc atttacttca cctaaaaaaa
    15601 tctattctgc tacttacgca gacgcacatg atgctgactt agttgttatt acagctggcg
    15661 caccacaaaa accaggtgaa actcgtttag acttagtaaa caaaaaccta aaaatcaacc
    15721 gcgatgttgt cacacaaatc gttgaatcag gatttaacgg tatcttttta gttgccgcta
    15781 acccagtaga tattttgact tactcaactt ggaaattctc aggtttccct aaagaacgcg
    15841 taatcggttc aggtacctct cttgactcag ctcgtttccg tcaagcactt gcggaattag
    15901 ttgacgttga tgcacgtaac gtccatgctt acatcttagg tgaacacgga gattcagaat
    15961 tcccagtttg gtcacatgca aatgttgccg gcttgcaaat ctatgaatgg gtaaaaaaca
    16021 acccagaaat cgatgaagaa gctatggtta acctattctt tggcgtacgt gacgctgctt
    16081 acacaattat cgagaaaaaa ggcgctactt tctatggtat cgcagtagca ttagcacgta
    16141 tcactcgtgc catcttagat gatgaaaatg ctgttcttcc tttatcagta ttcatgaatg
    16201 gcgaatatgg attgaacgac atctacattg gtgcacctgc tgttatcaac cgtcaaggta
    16261 tccaaaaagt aatcgaaatt cctttaagtg acagcgagca agaccgtatg gctgcttctg
    16321 ctaagcaatt aaaagaaatt ctagatgaag cttttgctaa actagacgct gaataatctt
    16381 tgaacatgac ggaaaacatc tattcggtgt tttccgtttt tttattttat cacccttatg
    16441 gtttctaaat tttttcataa agtagagata accttcgtct tttcctctaa attatgctat
    16501 catgagaccg ttccacccta aacttttact taaggagttg tcgatatgac aagatcttcg
    16561 catcgaaaaa aatcgaaaca tgttgctttg ctttcagttc ttggtgttct cttagtgctg
    16621 atcagctttt atacctatcg cagtacatac tacacaaagc attttttgcc gaatacagaa
    16681 ataaatggaa taaatgtcag caatctaaca gtcgaaaaag caaatgaaaa attaaaagaa
    16741 gcttattctg ataaaaaact ggctattaaa gaagatggaa aagtctggca ggaagtacca
    16801 aaatccgagc tcggctacaa agatgatttc acttcggagc tttctccgat cctaaatgaa
    16861 caaaacggat ggacttgggg aatgacttat gtctcagcgg cagaaaaaca agaaatagat
    16921 cctgtcagtc aaaaccacca aaaactagac actaccgttc agacattgac aactaagctg
    16981 actgatttga acaaagaccg gacacctact actgatgcaa cgatcgaaaa agcaggtgac
    17041 tctttcgtta tcaagcctga agtcaatgga aatacgatcg acgtcgatgc tgcggtcaaa
    17101 caattaaaaa gtgcggtaaa ctctggtaaa gatacaattg aattgactga attcaaagaa
    17161 aaaccaaaag taacatctga agacagctca ctgaaagaac aactcgcatc catgaatgct
    17221 atcgcaaatg taaaagctac ttacagtata aacggtgaga ctttccagat cccatcaagt
    17281 gatattatga gttggctgac ctacaatgat ggaaaagtcg atttagatac agaacaagta
    17341 cgtcaatatg taacagattt aggcacaaag tataacacaa gtacgaatga cacaaaattt
    17401 aaaagtacaa aaagaggaga agttacggtc ccagttggca cttacagttg gacgatccaa
    17461 acagacagtg agacagaagc attgaaaaaa gcgattctgg caggccaaga ttttactcgt
    17521 tcacccattg tgcaaggtgg cacaaccgct gatcatccat tgatcgaaga tacgtatatc
    17581 gaagttgatc tggagaacca gcatatgtgg tattacaaag acggaaaagt ggcccttgaa
    17641 acagatatcg tttccggaaa gccaactaca cctacacctg ctggagtctt ctatgtttgg
    17701 aataaagaag aagatgcaac tttaaaagga acaaatgacg atggaacacc ttacgagagt
    17761 ccggtaaact actggatgcc gattgactgg acaggtgttg gtatccacga ttcagactgg
    17821 caacctgaat acggtggaga cttatggaaa acccgcggtt cacacggctg catcaacacc
    17881 ccaccaagtg taatgaagga attattcggg atggtcgaaa aaggaacgcc tgtattggtc
    17941 ttctaacaaa aataatatat aaaaagaaag cacccgtacg attggtacag gtgctttctt
    18001 tttattatct aacaatgtgc tacttacatt tcagcagcag taaagacttc tgaaacatca
    18061 tcatcgtctt ctagcttatc tactagacgt tccaattgct ctttttgttc ctcatttaaa
    18121 tcaatcgtcg tttgtggaat catcgtcaat tctgcttgcg ccaaagtgaa ctctttttcc
    18181 aactcatctc gtacagcagc aaaatcttct ggtgcagtat aaatctcgaa tacttcagga
    18241 gaagtttgca gatcttctgc ccccgcctct aatacatcct caaacatcgt ctcttcatca
    18301 acagtcaacc catcgcgttc aatagcgata tatcctttgc ggtcaaacaa gtaactgact
    18361 gaacccgttt ctcccagtga tccaccgttt cgagtaaaag ctactcggac atttgtcgct
    18421 gtccgattac ggttatctgt caatgcatgg actaagattc ctactccacc cggaccatat
    18481 ccttcatacg tgatttcatc gtaattcgtt tcatctacgg cactcgtagc ctttttaatc
    18541 gcccgttcca cattgtcgtt aggcatattt gcagcttttg ctttgtccac aacaagccgc
    18601 aaagctggat tcatagatgg atcaggaccg cctgctttag ctgccatata aatttcacga
    18661 gaaagtttct gaaagacttt ccctcgtttt gcatcttggg cattttttct tccttggata
    18721 ttatgccatt tactatgtcc tgacatgatt tttcctccct tgttcttttg agaatacact
    18781 tctattctag tactatttca caaaaaaaca aagccacagc caatctataa acgcttcttg
    18841 aatgccgcaa aaagcacaca taatatcaca gcagtcagag caccgatcga atccaacatg
    18901 acatcttgga acataggtgt tcgtccaccg gtcatcatct gatggaattc gtccaaacct
    18961 gcgtaccctg ttgctgaaag ccaagcaagg atcgctgtca gccaccaaat ttttagcttg
    19021 gggaaaacac ctaaaaacaa gctgcctccc aaaataaaat aggtaccgaa atgtgcgccc
    19081 ttccttaaaa agaactctaa aaatttggcg tagcccagat ggtcgatact caccatactt
    19141 ccaccataat taaaacgtat acccgctaat gtgtctttaa atggctgatt aggcagccag
    19201 ctttctaatc gcgaaacttg tgattgctgt ccgtaagttt gagaagaact gtaaaataag
    19261 attataacga ctatcagtgc gattactaaa taaatatttc cgtttttcat ttgttttttt
    19321 gaagaattca taagtcacct ctgtatttta tcttagactt tttttgaaga aacaacaatc
    19381 attttcatag agacttcttc cataaaaaag tgctatactt aattttgtat tacaatatga
    19441 agggagtttt ttcatgagtt attcattaaa ttggaatcta gattctattt tttccggagg
    19501 cagtcattct gatgctttga accaacggat gaagcaattg gaagaccaaa tgaacgagta
    19561 ttatcaccgc gtaacaaaat ggtcacctag ttctgacaat gcagagcagt taaacgctat
    19621 tcttcaattg caagaaacga ttacgaatgg ttttacccaa tgcagcagct atattactgc
    19681 attgctttct gccaatgtca atgattcaga tgcaaaggtc ttatcaggca agctttacgc
    19741 aatgctgcct cgtctgcaat cagccgaaac tgtattgtca aagaaatttg cagaaatatc
    19801 tgacaatgat tggaatcaga tgctttctca atcttcgttt gaaacaattg cttttcgttt
    19861 aaacgagatt cgtcgtgatg gctcacaatt attatcagaa gctgaagaaa acattataaa
    19921 tacgctttct ttagatggtc taaatgcttg gagcagtcat tatgatacga ttgtagccag
    19981 catttcgatt cccttcgaac aagatggaca agtagtcgaa ttatctgctg gacaagcctt
    20041 caataagatg atgggcgatc cagatccaaa agtcagagaa acacttttcg cagcatggga
    20101 agaagcctgg aaagaaaagg cacccctctt cacggatact ttgaatcatt tagatggttt
    20161 tagactttct gactatgaac ttcatggtgt cacagatttt ctacaaaaac cattagagta
    20221 caatcggttg aagaaagaaa cattgtctgt catgtgggat acaatccaga aaaacaaaca
    20281 accccttgtt aattacttga ctagaaaagc taatcttttc ggtaaagaaa aaatggaatg
    20341 gcaagatcaa gatgcaccta ttattttagg cgatttgaaa gaaaaaacct ttagttttga
    20401 cgaagcagca gcatttatta tcgaaaactt taacaaattc agtccaaaaa tggctaaatt
    20461 tgcccaatct gcttttgaaa agagctggat cgaagcagaa gatcgtcctg ggaaacgtcc
    20521 tggtggttat tgtactgagt taccagaaac aaaagaatca aggatcttta tgacctacag
    20581 taattctgtt aatgaggttg cgacacttgc tcatgaacta ggacatgctt tccatagcag
    20641 cacgatgtgg gatttacctt ctttaaatcg cgaatatgcc atgaatgtcg cagaaacagc
    20701 aagtacattc gcagaactga tcgtagccga tgctacatta aaagtcgcaa aaacaaaaga
    20761 agaaaaaatc aatttgctag atacaaaact gcaaaatgct ttagctatgt tcatgaatat
    20821 ccattcccga ttcatttttg aaaatcgatt ctatgaagca cggcaagaag gattagtctc
    20881 agaagataag atcacagaga tgatggttga ggcgcaaaaa gaaggctatc aaggagcttt
    20941 agctacttac catccatatt tctgggctgc aaaattgcat ttctttattg atgacgtacc
    21001 gttttataac ttcccataca catttggcta cctctttagt ttgggcatct atgcttacgc
    21061 caaccaaaag ggagcaaatt ttgaagaaga atatatccat ttactacgcg atactgcctc
    21121 aatgacgacg gaagatcttg cgaagaaaca tttgaatgtc gatcttaccc aaccagattt
    21181 ttggcaagca ggtatcgaca tggtgactga agatatccaa acgttcatgg aattgacaga
    21241 agaatttatc tgatttctat tttatcacaa taaaaaaaga gttagtccag aatgggctaa
    21301 ctctttttga ttaatcattc ttacatgctg acagcaaagt caggggcaaa ccattgaact
    21361 gaaccaactt ttacgctttc gcctggttga ggagcatgga tatattgtcc tccgcctaaa
    21421 gcaatcgcta cgtggtaagt tccgccttgt gacccccaga ataacaagtc tccagctttt
    21481 gcttgagaaa ctgaaatttt tgttccagct gattcttgag gaactgtcca accaccgatg
    21541 tcacgaccag ttacttgcat gtaaacatag cgtgtgaacc ctgagcagtc aaagccactt
    21601 ggatctttac cgccccaaac atatggagta ccaatatatt tgtaagcttc tgctacgatt
    21661 gctgcaccat tcacacttcc agaaggagct ggagcaggtg ttacaggttt tggttgttca
    21721 ggtgttggtg ttggcgttgg agccggagta ctacttcctg tgccgtttcc tgtatcaaca
    21781 ctttgatctg ttgatggtgt tgtaggcgca ggtgttgttg attcttctgt tgttgaagat
    21841 tcaggcactg ttgttgattc ttctgttgct gaagattcag gcactgttgt tgattcttct
    21901 gttgctgaag attcaggcgc tgttgttgat tcttctgttg ctgaagattc aggcgctgtt
    21961 gattcttctg ttgaagattc aggtgttgtt gattcttctg ttgctgaaga ttgtgtagct
    22021 gatgatgatt cttcagtcat tgaagattgt gtagctgatg attcttctgt tgctgagctt
    22081 tgtgcagtag atgaagcttg agtagcttgt gcttcagcct ctgcttgttc gcgtgcttct
    22141 ttttcagctt tttcttgtgc agcttgttga cgagcttgtt ctgctagacg ttgttgttca
    22201 cgaatacgag cttgctctgc ttcagcttct gctttttgac ggttcaagtc agctttcttg
    22261 tcttcagcag ttgcttgttc agcagctaat gaagttttca gtacgttcaa atcagcttgt
    22321 ttagataaaa gatcgccttt ttgagattcc aaagcagctt ggttttcagc taattctttt
    22381 agtttagcat cgttttcagc ttttttgtct tctacagctt ttttatcttg tttttgttgt
    22441 tccatcaagt cgttgtttgc ttttaccatc gttgtcattg cttgaacgcg tccaatagca
    22501 tctgctaatg aatcagcatt caatacagca tcgatgtagt ttgagcttgt gttgcttact
    22561 tgtgcttcgc gtgcttgttt ttggattgta tcttcacgtt tttcaatacg ttcttgtaaa
    22621 tctgcaatgt cttttactaa ttgtgcagat tcttgacgca atgtatcttg ttttgctaat
    22681 aggtcttgtg cttgtgtgtt gatttcagaa acttggcttt ctaaggcatc gatttgtgat
    22741 tgtgcatctg cttgttgatt tttcaagtct gcaatctttt gatcttgctg ttgtatctga
    22801 gaatcaaaat cgtccgccgc ggcagcgatc ggtgatgcta cggcagtcaa ggtcattgaa
    22861 cataccatta ctgctgatat taaactcttt ttcactcttc attcctccga ctggcttaat
    22921 ttaataaata tctaaatata tttaagtctt tcttaacgat ataaaaattg taccatagca
    22981 gtgtgtcaac gatataatag ttatgttaca aaaatgtttc aaaacaactt ttaaaaatga
    23041 caaaactgtt cgtttcagaa aatgatcatg aaaaagccgc gttaagtcta gcatttctta
    23101 agataacaac gattcttttt cgctttcgac ctaaaaataa aaaaagaaat tattcatcac
    23161 tgaataattt cttaaaggga aaaatgaata atacaaatat aatcatgttc aacagcagtg
    23221 taggtcctaa aaaccttgta ataaaatacg tgttatttac tactgctaat ttaaaaatca
    23281 actggaccac catcgtaaac aattcataac ccgtgacaaa gatgatcata ctgaaaaatt
    23341 cagtaaagat gttgacatgg ataacgtctt tcattacata catcaaccat acaattaaag
    23401 ggagagctac tgcatagata ccgataacgc caatatagta agcgtcatag atagccccga
    23461 gaacaatcgt ggtaatcagt aaataacgtt tttcaaacgc catactgcaa cataataatg
    23521 ccaatatcag aaagtgggca tttgacatat aggtgccttt cgaccactcc cctagcattc
    23581 ttgttaaatg accatctatc aacatcaaaa agaacaaaac gattggcaga tagtacttca
    23641 ttgtttcttt cttcaacatg gactaatcct ccgctagccg ttggacaatc gtcacaactg
    23701 acacgtcata catttctgca taaggtttca cataaacttc ccgatccagc ccataactat
    23761 ctggtttcgt tttaataacc gtaccgatcg gcaagttagc tggagaattc cctccaagac
    23821 cggatgtctg gacaacatcc ccttctttga tatccgtatc accagttaat tgggtcacca
    23881 ctaaggcatg gagcttttca tcatagtttt taagcaaacc aaacgcttcg ccattagccg
    23941 aagatacccg tactggaaaa tgattggagc tttcattaga ggatgacagt aattcgattt
    24001 tagacgaagc cgtattgacc tcgatcactc ggccaatcaa tcctttttgc gacatgactg
    24061 ccatatttgc ttcgataccg tctttagaac ccttgtctac gatcagcatg tcctgccaac
    24121 tgtcaggcga acgagtaatg acatttgccg ttactttttc gtaactagtc agcgtctgat
    24181 tcaactcaag ttcttttttc aacgcttcga tttctctctc gtaattcttg ttttgctgtg
    24241 aaacgtcatc atagctatcg attttttctt ttagccgctc attttcggca taagttgaaa
    24301 aaagattatg gacagaatct actccatttc gtacccaccg tactggggca gagattgttt
    24361 tatcaaccat tgcaacactg tcattaacga tggattggaa gaaattgggc tttccttcat
    24421 tcgctcgctg cgcagcggtc acacttagta tcgtcaccac gatgataaca ataaccaagg
    24481 taataataat atttttatta ggattgaact tcttcacaaa gacacctcga attaattaga
    24541 ctcttgtgtt caattttatc actaaatgcc gtgaaacaaa aggtaagttg ctcctcttaa
    24601 gctttttttt agcaaataat agattctgtc atttttagcc tgaaagacaa atttttttat
    24661 ttgtttatgg atcaatcttt gctttgaata actgcaatca taccatctga aaaagaaaat
    24721 tctgcggtat ctgaaagaaa ttcgttactt gcataagatg tcggatattc tacttcttta
    24781 ttttccaata catacttgct gccttttaat gtaagattcg agacgggagt caagcagcaa
    24841 taagctaaat acttcatatc tggtatctgt cttactatat gctctccagg caaataataa
    24901 gacaaataat tttgacaatc tctgataata agctgatggg caaagggttt gaagcgaggt
    24961 tccataccta accagagatt ggctaaaaga tgatccaatc ttccgcccgt agctccaatc
    25021 aaagtgactt ccgcttgcgg gtaacgttca aatgttttta agatacctaa ctgtgtatct
    25081 gtatcgtctt tttctgcagg ggaacgggta tactctttgg cttttgcaaa tacttccttc
    25141 tgctcttcgt tcgacaatga atcaaaatcg cccactgcca gatctactgg gtagcctgct
    25201 tgaagcaggt acagcgcacc acggtctatc ccgacatagg catcgtattt ggacagcaga
    25261 gactgcggcc agttttgcgg attacctcca gcagctaata aaattttcat ttagtctaat
    25321 gcctctttta atcgttcgat ttgtccgact ggattttcgg ctccatagat atatgatcct
    25381 gcaacgaaga catccgcccc tgcatcttta cagatttttg ctgtttctgg aacgattccg
    25441 ccatctactt cgattgcata agtccaattg ttctctctac gtagatcagc gagttccgta
    25501 attttttcta ctgtttcttc aataaagctt tgtccgccga acccaggatt gacagtcatg
    25561 actagtactt gatcagccaa aggcaaaaca tgtttgatca tggagactgg tgttcctgga
    25621 ttgataacta ctccagcttt aactcctaag ctttttgtca tttgaagtgc ccgatgaata
    25681 tgaggagttg cttcgacgtg gacagtaatg atatctgctc cagcttttgc aaatgctgga
    25741 atgtagtttt ctggatcaac gatcatcaga tggacgtcta acggtaattt agtaacagga
    25801 cggattgcct gaacaatatt tggccctaat gtgatatttg ggacaaattg gccatccatt
    25861 acatctacgt ggatgtaatc tgcgcctcct ttttccacta actcaatgtc tctttgtaaa
    25921 ttggcaaaat ctgcactcaa aatggatggt gctatcttca ttcttgtttc ctcctatttt
    25981 cgtttacctt ctttttttgc atacattggt tttctttttt cgatttcttg taagaattgc
    26041 aaataattgt cgtaacgtgt ctgtgcgata ccacctgttt ctactctatg ttttacttcg
    26101 cagccaggtt ctttagcatg catgcactct ctaaatttgc aatggacaga agcttctaca
    26161 aattcaggaa attgtctcgg cagttctcct gcttcaattg tcaaaaagtc aatcgagcta
    26221 aatcctggtg tatctgctac taacccgcca tagataggaa tcagttccac atgacgtgtt
    26281 gtatgccgtc ctcttccaag tgcatcagaa atctctcctg ttgctaaatt cagttccggt
    26341 gatatttgat tcagtagcgt cgattttcct gctccagact gacccataaa gaccgatagc
    26401 cgttctggga agtaacggat cagttctgtc gtatcacccg tatgattggg tacaatcacc
    26461 ggatagccta ttttagtata ggtttgcttg atctcttcga ttttttctgg gtcgtctgac
    26521 aagtcggtct ttgtcaaaaa aataatcggt tcgatcgact cgtattccaa ggtaactaga
    26581 aagcggtcaa gtagattata agaaaatgca ggctctacga tacttgtgac aatgattcca
    26641 agatcaacat ttgtgactgg tgggcgaact aattgatttt ttctcggcaa gatttccaga
    26701 agatagccgt ctgtttgatt ttcactctca aagatcacct gatctccgac aagcggcgtg
    26761 attttccgat tccggaaatt tcctcttcct cttgtttgat aggtctctcc gtttgcgtat
    26821 acatagtaaa aaccgctgat tgcttttctg atttgtcctt tgataagtgc cacctccgtt
    26881 tttgtttatt ttaccatacg aagaggaaag taggtgttat tccatgcaaa cttctcaaag
    26941 tatatggctt gaaaattgat caaaagagat agaaacacaa aaaagagaat gcaacaaatc
    27001 aatgtcgcat tcccttctga tatattttat tcagcactta ttttgaactt tctgaggtgc
    27061 tagctgatga acttgtggag ctggaagatt cttcttttga agagttgctt gtgctactgg
    27121 agctacttga gctgctagaa ctgtctgaag agtctttttc agaactagaa gacgctggat
    27181 ctggtccttt agagtaaatt acgttcacaa ccattccttt ggtaattgtc gttcctgccc
    27241 ctggtactgt acgaatcact ttatctttat ccaccgtgtt tgaatattcg gaagtctcat
    27301 gcccgatata ttctgcaccg acactagcta aataactttg tgcttcgctt tttgtatagc
    27361 cggagatatc attcaattta ggctctgttc cttggcttac gacaaaattg atgtaagttt
    27421 cttctgctac aacttcaccc gaggctggat cctgactgat gatcgaacct gatggtacag
    27481 tgtcgctata gtcataagta gcactaatat tattgatatt gaatccttgt gtaacaagcc
    27541 aattacgaac agtttcgtag ttttctccta catgactact caaagtcact gtttctggtc
    27601 ctttgctgac tgtgaaagta atcgtgtctg ttttaggatc gacttctgta tcttctgatg
    27661 gagattgcga aatgatcatt ccgctttcta cctctgaact gaattcctct tctttttgaa
    27721 tcaagtcagc agaaaaccct aattctttca aacttgcttc ggcatcttca taacttttac
    27781 cactgtaatc atctaatttg atttttttcg tgccgctact aatatacaga gtgacttcgc
    27841 gtttttgctt gactgtcgtt cccgctgccg ggtctgtctt cactacatta ccttcttcga
    27901 ttttgtcatc tgcaatttct tctgtttttg ttgctacttc taatttcgct tttgcgagtg
    27961 tttctctagc agaagcttca gaaagatcag aaacatcagg aacaacaact tctcctcgcc
    28021 cgccagaagc aaagaataca gctgttccga ttcctaaaac agcaagaata gctaatagga
    28081 tcagccacca ttttttctgt cctttctttt taggatcagg cagaacttct tcctcctctg
    28141 gcaaggtttc gttttctggc ttgtcttttg gcagaggcat agatttgaat gaatcaggca
    28201 ttggtgcatc ttccgtaagg ggtgtgataa cttttgtttc attatccatc acatgaggct
    28261 gccatttttc ttcgtttgca cgagctggtg ataatactgt agaaagatca tcagacattt
    28321 cctcggctga cttataacgg tctgcaggtt ctttagccgt tgcccgtaaa atcacgtttt
    28381 ccagtgcttg tggcacattt ggatcaagtg cttttataga tggaagatca tcttgaaaat
    28441 gttttaaagc aattgttaca gcagattcac catcaaacgg tacgctaccc gtcaacatct
    28501 cataaaggat gatccctaaa gcataaatat ctgactgctt cgttgccata cttcctctgg
    28561 cctgctcagg ggacagataa tgaacagatc ccagcatcgt attcgtctgc gtgatcgatg
    28621 tttcagataa agcgatagca atcccgaaat ccgtgatttt tacaacacct tcattatcga
    28681 tcagtacgtt ttggggtttc aaatctcggt ggatgatttg atggttatga gctaaagaaa
    28741 tagcagaaag gatctgctgc ataatattta ctgctgtttc ataaggaaca ggataatgtg
    28801 tttggatata tcgtttcaag tccattcctt tgacgtattc catcaccaga tactgcatgt
    28861 tgtcttcttc accaacatcg taaacactaa caatgtttgg atgaacgagt tctgttgctg
    28921 ctaaagcttc tctctgaaat cgtcgaatcg cagtctggtc attttgaaag tcaaatcgta
    28981 agactttaac tgctacatca cgatccaaga ttaaatcgtg cgccaaaaat acatttgcca
    29041 taccaccgct accgatattt ccagtgattt gataacggcc atttaatttt ttgcccaact
    29101 cgatcataca ctgtcctcct tatattcgat aagaagaacg gtgatattat ccgctccgcc
    29161 tgcttcattg gcacgatcaa tcagctcagt tactttatga gacaatgggc cttcttgatt
    29221 gatgatcgtt cctatttctt cttcagacag catgttcgtc aagccatctg aacataacag
    29281 cagtcgatct tttagttgcc aaagatgagt agaaacatct acttcgactg ttccaggcat
    29341 gccgacagaa cgtgttaaaa tatttttcct tggatggttc actgccattt cttcgctgat
    29401 ttctcctgat ttgactagtt cattgactaa agaatgatcc tccgtcaatt gcatgatttt
    29461 atcttcacga atcaaataag ctctgctatc cccaacattg gcaatcgtga accagtcatc
    29521 tgacagagcg gccgctacga ttgttgttcc cataccgtta tattccggct gttcttgtcc
    29581 acgctgataa atcagcatat tttcttcttg aatcgattga atgaaccatt gggcgatttt
    29641 ttcatcgtca acagcttctt gtttttccca agcttcgcct agattcgtta ccgccatctg
    29701 actggcaatg tctccggcac gatgaccacc catcccgtct gctaatacag caagcttgag
    29761 acctgaacgg ctggtaaata cactggcata gtcttgattt gtgttacgtc gtcttcctac
    29821 atctgattga tattcaatct gcattttttc acctcattac tttttgcgca aacaacaaat
    29881 gaaaaatcca tctgtgtaaa actgatgcgg atacaaagtc aacattttct cttcgattga
    29941 tgattgtagc ataggattgg tcaaaacatc aatcctctca aaatcagggt gtctttccaa
    30001 gaaagcagaa acaacgtctt ggttttcttc ttttaagatc gtacaagtgc tataagtcag
    30061 aataccggaa gactttaaag ttggtgcgca gctttctaaa atttccaatt ggatttttgg
    30121 taaattcgct aattcatccg gctgtttttt ataacgaata tctggttttc gccgaagcag
    30181 cccaagacct gaacaaggcg cgtctactaa aatccgatca aactgctctg cttcgaactg
    30241 tttactgact tctctagcat ccatcttttg agcgtagaca gcagaagaga cacctagacg
    30301 tgctgcatta tcttcaatga gtttgacttt gtgttcgtgt acatctaaag cgaccacttc
    30361 tccaccgcat gacggatcta aaaaagaagc aatatgcgtc gtcttacctc cgggtgctgc
    30421 acaggcatct aagacatgat gttcaggctc gatttgcata gacggcgcta caagcatcga
    30481 actttcatct tggatcgtca tgacgccatc gtggaacaat gagctagaag ctaaatgccc
    30541 ttttttcgct actataccgt atggactgac ttggcttttt tcagctgtga tctcttcttc
    30601 ttgcaaaaca gtgatggcct gatctctgga aagtcggcgt gtatctactc gggcactagc
    30661 atggctaggc tgatatagcg ataaaccgag cttttcagtt tcttcgtatc cgatttgatc
    30721 caccagtcgt ttcgtcatcc atagaggcag gctgattttg acagaaagtc tttcgatagg
    30781 atcagcaatg ccttgcagat ctggtgctcc ttgacgctga taattcctca agacaccatt
    30841 tacaaatttc cctgtcccag gatttccttt tacttttgcg atttcgaccg cctcgtttaa
    30901 aatagcatgt gcagggactt tatctaaaaa ttctaattgg tatacagaaa gataaagaag
    30961 cgtcttgacc cagtcatcca ctttttttgc tttagcgatc aatggtgcaa cgtaaaattc
    31021 caatagtcgc tgatggctaa tcgtaccata gatcaattct gtaaataaac ccacatcttt
    31081 ttgatttagc tcgctttgtt tgatcatctc attcaacaaa agattcgagt aggcgccacc
    31141 cttgttcact cgctctaatg tcagtaatgc catatatcgt actgattttt tcattttttt
    31201 agggattttt ttcattattt cacctgctga ccaatctgaa cttgctgacc gcttccgtta
    31261 aggaaatcat gtacggcctg ttttccttta ccagctggct gtaattcatt gatggctaag
    31321 acggtctgtt taccgcaagc aatccataga ttttttttgt ctttccggat gatcgtacca
    31381 ggtgctttgt ctgtagtttc tgccaatact tcaaccgata ataatttcca gcgtatgccc
    31441 tcataggtcg tgaatgcaat tggccaagga cgcattccgc gtacttggtt gtcaatttct
    31501 tctgcagttt tatgccaatc gattgcttct tgttcccgtg tgatgtttgg cgaaaaagtt
    31561 gcttctgact cgtcttgagg tactggtttt tgtccatcca aaatattggg caatgtttct
    31621 agcaatagct ttcttcctaa aaggctaagc ttttcaaaca tcgtccctac atcatcttgt
    31681 ttagtgattg gtatgctttc ttgcgcatag attccgcctg catccatttt tttgatcatt
    31741 tccatgatcg ttacaccagt ttctttctcc ccattcatga tggcataatg aacaggcgca
    31801 cctccccgat atttaggaag taaagaagca tggacattga ttgcccctaa ttttggtact
    31861 tgcaataact tttcaggcaa gaattggcca aatgccgcag tgacgatcac atcaggcacc
    31921 aattcaatga tttcttccat ttctggcgaa ccggagattt tctctggctg cagcacacgg
    31981 ataccgtgct tcagagccgc ttcttttacc ggtgtcggcg taattactcg tttccgccca
    32041 actggacggt cgggctgtgt taccactgcc tggatctcgt aacctgattc tatcagccct
    32101 tcaagaatcg gcacagaaaa agcaggtgtg cccataaata ctagcttagt catcaagatg
    32161 ttcctccata tattcttcaa gttcttcttc cgggatctgc tgtatcattt tctcaatgaa
    32221 caagataccg tctaagtgat cgatttcatg ctggaaggca cgggctaaat agccaaaagc
    32281 cgtcacttct atctcttctc cgtctcgatc ataataacgc acggtcactt catctgctcg
    32341 cttgaccgtt ccatagacat gcggaatact gagacaacct tctacgtcaa ggctttcacc
    32401 ttttgcttcg atgatttctg ggttaatcag ttcaaatttc tcgccttcat ctacttcgat
    32461 cacagcaatt ctcttgtttt gtcctacttg aggagcagcg atccctattc cgtcattcgc
    32521 aatcattgtc tcatataaat tgtctaataa agcgattgtc tcgtccgtga ttacatcgat
    32581 tggctgagca gttcttttta atttatcatt agggtggatc aatataggat agcgcataat
    32641 ttggcccttt cttaaataaa gtttaatggt tcgttgtcaa ttgccacaaa aagaccttgt
    32701 cgctgttctt tctggcttcc attcaaaatt tcatccaaaa catgaggaag attcggttca
    32761 tgtttatatt tgatgattag ttgataataa tatcggtttt tcactctcaa aatcatgctg
    32821 ggcgttggcc ctaatagcaa gctttgaggg cttaacactt cttttagctg attggcaatc
    32881 tgaaagattt tctttgccgc tacttgttct tcaggatggc tggcggttat tttcacagta
    32941 aagtaataag gaggatagcc tccacgatgc cgtacatgca tttcctgctg ataaaactgc
    33001 tcataatttt gttttttagc taattctatg gcgtaatgtt gaggattgaa tgtttggatc
    33061 acgacttcgc ctgctttttc cgctcgccct gctcgtcctg aaacttgggt aagcaattgg
    33121 aatgtatgct cactagaacg aaaatccggt aaattcaggg aggtatcagc attcaacacc
    33181 ccaactaatg tcacttctgg aaagtccaaa cctttagcaa tcatttgtgt ccctaataat
    33241 atatctgctt cttttgcacc gaatttttgt aaaatctgtt cgtgtgcccc ttttcttcga
    33301 gtggtatcta catccatacg caaaatccta gcttgcggat aaagttctcg gagttcctct
    33361 tctacttttt gagtacctgt tccatagtag cggattttat tgccgccaca attaggacag
    33421 cgattgggaa taggttcttc atgtccgcaa taatggcagc gcattgaacg tgtatccata
    33481 tgcagtgtaa gagagatatc gcaattagga catggaagaa caaatccaca gtccctacac
    33541 atcacaaaag acgaatatcc tcgacgattg agcagtagga cagtttgttc ttttttgtct
    33601 aatcgatttt gtattttttc ctgcaaatta gcagaaaaag tagaggtccg atgattctga
    33661 aactcttcac gcatatctac gatctcaata gctggaagct gtgcagctgc tttggctcgg
    33721 tggtttaact gcaataactg ataaacgcct ttttgagctc gtgctcttga ttctaaagag
    33781 ggcgtcgcgc ttcctagaac tattgggcaa tgatgatatt tactgcgcca aattgctaga
    33841 tctctcgcat gataacgcgg tgtctcatct tgtttgtaac ttgattcatg ttcttcatcg
    33901 ataatgatca gcccgatatt tttcagcggg gcaaaaatag cagatcgtgc gcctactact
    33961 acttgcgctt cttcccgctc aatcttgcgc cattcatcat atttttcacc ttgggaaagt
    34021 ccgctatgta agaccgcaac tgattctccg aagcgtcctt tgaatcgctc gaccatttgc
    34081 ggagtcaatg cgatttcagg cactaacata atagccgttt tattttctga caaaacatca
    34141 gcgattgcct gaagatatac ttctgttttc ccgctgccag tgattccctc cagcaaaaag
    34201 acctgatctt tttgctgctg acctgctgtg atgatttgtt cgacagcatt tttttgttct
    34261 gcattcagtt ccaatgccgt cgtttggtca aatactcggt ctttataagg gtcgcgataa
    34321 cgttctgatt ctataaactc cagccagccc ttttcttttc cttgattcaa gacagcagta
    34381 ctgattcctt tatttttgaa ataagcaatt ggttcttctt ggctcagttc agataaacac
    34441 aaaagaagtt ctttttgttt cttggcattt tgccgtaatt ttgcccattc ttcttcgatt
    34501 tgcttttcag ttaacaaaga acggaccaaa cgaatcgttt ttactttatt tcgtgtatgg
    34561 acttcatatt tgatatctac taattgctct tggcgccagc gaatcaattg agaaaggctg
    34621 ccttcttctt ctgcttcctt ccaggaaatc acttctcgct gatcaaacaa tacctgaact
    34681 tctggtgtgt ctgccaaagg atagatcaat ttatcatatt ctgctttcat cacactcgga
    34741 agcatcgttt gtagacaagt gattttgaat gcgtaagtaa tttttttcat ataatcagct
    34801 aatgaaagta attcttcatt gaccaccgga gcaaggtcta gcaaacgaat aactgccttc
    34861 aaagatggat tagctgattc ttctgatttt tggatagcca taacaaatcc ttggacatga
    34921 cgattgccat taccaaaagg gacttctact cgcatcccga cttgcaaagc tgtttccatt
    34981 tcagagggaa ccaaataagt gaatggctga tcggtctgca tagtaggtac gtccacaatg
    35041 acttcagctg ttaatgtcat ggttcgtttc ctcctttttt tgtcttttct tatcaagcga
    35101 caaaaagttc cttgcctatt ttactagaga tcgatggatt tgtcttatct tctgccaaat
    35161 cctaacaaaa aattaacagc agataagaaa aaaaagaact gtgtcaaaaa gttcagacac
    35221 agccttttct accagacaat aagtggcgaa tgtttgaaaa ggaaacagct gggtttgctt
    35281 ttctttttag atgttcgctc tatttttctt tattacattt tttgctcttc acggatacgt
    35341 gattccaatt cgtgttgttc acgctctttt tgtgcttgac gttcctcttc ttccatcttc
    35401 aaacgttcac gttttaattc aggatgtgga tcattgacta catttcctgc atcgatttct
    35461 tctaaagctt gaccgacgct ttttactgaa tcaaaagaat ctagagtagg ctgtgcactt
    35521 gcatccaatt catgcgcgcg tttacttgct aaaatcacta gagaatattt tgaatttaca
    35581 cgatctaata gtgagtcaat tgaaggtttt aacatcataa gactacatct cctttaacat
    35641 tttaatatat ttaccgatta cgcgatctac tcgaaaatgt tcactggcaa taatgttttt
    35701 gattcgttca actgctagcg gcacttcatc atttacaaca gcatagtcgt aaagagccat
    35761 catttcgatt tcttcttttg caactttcat tcgttcttcg attacttcat ctgcatctgt
    35821 tcctcggcct acgatccgtg attttaattc cgctaaatct ggcggagtca aaaagatgaa
    35881 tacaccatcg ggcacttttt ctttgacttg ttttgctcct tggacttcaa tctccaagaa
    35941 aacatctttt ccttcatcca atgtcttgtt gatatatgac aaaggagttc cataataatt
    36001 cccgacatat tctgcgtatt ccagcatctc tccagcttcg atcattgatt caaactcttc
    36061 tttgcttcgg aagaaataat caacgccttc gacctcccct tcacgcattt tacgggtagt
    36121 cattgagatc gaatactgaa aatcattatc ctcactctca aaaattgctt ttcgtactgt
    36181 gccttttcct acaccggatg gaccagacaa cacgattaat aatccacgct ctgacatgac
    36241 gacgtccttt caactagtct ttttgtactt atcgtttatt ttgcactttt tttctgcaac
    36301 tttcaaggtt atctttaatt atagctagaa attggtaaaa aagctaccct gtaccaagag
    36361 gtcgtaaaaa agctgtcctg catcaagtaa taagaacagc caaacataaa cagcttctca
    36421 tgtttttcgt ttggttgggg ttattatcgc agatgcaagc ttttgaacgc cgtgtataag
    36481 aggtcgtgaa gaagccgatt agtttcgagt atgaagaaaa attttgtgaa aatagtttct
    36541 cacatttttg cataaatttg gcttaatac
//
LOCUS       DAFEKH010000028        34520 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.029, whole genome shotgun sequence.
ACCESSION   DAFEKH010000028
VERSION     DAFEKH010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34520
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.029"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(133..306)
                     /locus_tag="LP386_001517"
     CDS             complement(133..306)
                     /locus_tag="LP386_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1918757.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
     gene            754..3116
                     /locus_tag="LP386_001518"
                     /pseudo
     CDS             754..3116
                     /locus_tag="LP386_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
     gene            3484..4407
                     /gene="truB"
                     /locus_tag="LP386_001519"
     CDS             3484..4407
                     /gene="truB"
                     /locus_tag="LP386_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HBL1918758.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            4411..5352
                     /gene="ribF"
                     /locus_tag="LP386_001520"
     CDS             4411..5352
                     /gene="ribF"
                     /locus_tag="LP386_001520"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HBL1918759.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            5704..6489
                     /locus_tag="LP386_001521"
     CDS             5704..6489
                     /locus_tag="LP386_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL1918760.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            6502..7353
                     /locus_tag="LP386_001522"
     CDS             6502..7353
                     /locus_tag="LP386_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HBL1918761.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(7477..7929)
                     /locus_tag="LP386_001523"
     CDS             complement(7477..7929)
                     /locus_tag="LP386_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1918762.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(8394..8762)
                     /locus_tag="LP386_001524"
     CDS             complement(8394..8762)
                     /locus_tag="LP386_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HBL1918763.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            8912..9394
                     /locus_tag="LP386_001525"
     CDS             8912..9394
                     /locus_tag="LP386_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HBL1918764.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            9431..10441
                     /locus_tag="LP386_001526"
     CDS             9431..10441
                     /locus_tag="LP386_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HBL1918765.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(10556..11269)
                     /locus_tag="LP386_001527"
     CDS             complement(10556..11269)
                     /locus_tag="LP386_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918766.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(11459..12049)
                     /locus_tag="LP386_001528"
     CDS             complement(11459..12049)
                     /locus_tag="LP386_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HBL1918767.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            12533..12760
                     /locus_tag="LP386_001529"
     CDS             12533..12760
                     /locus_tag="LP386_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HBL1918768.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            12776..13942
                     /locus_tag="LP386_001530"
     CDS             12776..13942
                     /locus_tag="LP386_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HBL1918769.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            14176..15219
                     /gene="hrcA"
                     /locus_tag="LP386_001531"
     CDS             14176..15219
                     /gene="hrcA"
                     /locus_tag="LP386_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HBL1918770.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            15313..15876
                     /gene="grpE"
                     /locus_tag="LP386_001532"
     CDS             15313..15876
                     /gene="grpE"
                     /locus_tag="LP386_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HBL1918771.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            15927..17756
                     /gene="dnaK"
                     /locus_tag="LP386_001533"
     CDS             15927..17756
                     /gene="dnaK"
                     /locus_tag="LP386_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HBL1918772.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            17907..19073
                     /gene="dnaJ"
                     /locus_tag="LP386_001534"
     CDS             17907..19073
                     /gene="dnaJ"
                     /locus_tag="LP386_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HBL1918773.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(19155..19820)
                     /locus_tag="LP386_001535"
     CDS             complement(19155..19820)
                     /locus_tag="LP386_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1918774.1"
                     /translation="MELDFSSPYYVVVGQLSDNQQLCQERINPLLELLERVFSYYGQA
                     LLTVHRQQIIILVNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSF
                     LHAKQVCEWIAFHQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLF
                     KKTLACFSKNNGSIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLL
                     VQT"
     gene            19796..19969
                     /locus_tag="LP386_001536"
     CDS             19796..19969
                     /locus_tag="LP386_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918775.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            complement(20014..20751)
                     /locus_tag="LP386_001537"
     CDS             complement(20014..20751)
                     /locus_tag="LP386_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBL1918776.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(20753..22255)
                     /locus_tag="LP386_001538"
     CDS             complement(20753..22255)
                     /locus_tag="LP386_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HBL1918777.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            22514..24508
                     /gene="uvrB"
                     /locus_tag="LP386_001539"
     CDS             22514..24508
                     /gene="uvrB"
                     /locus_tag="LP386_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HBL1918778.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKEELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            24518..27334
                     /gene="uvrA"
                     /locus_tag="LP386_001540"
     CDS             24518..27334
                     /gene="uvrA"
                     /locus_tag="LP386_001540"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBL1918779.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            27597..28862
                     /locus_tag="LP386_001541"
     CDS             27597..28862
                     /locus_tag="LP386_001541"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HBL1918780.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            28866..29597
                     /locus_tag="LP386_001542"
     CDS             28866..29597
                     /locus_tag="LP386_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HBL1918781.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            29732..30616
                     /gene="rapZ"
                     /locus_tag="LP386_001543"
     CDS             29732..30616
                     /gene="rapZ"
                     /locus_tag="LP386_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HBL1918782.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            30613..31611
                     /locus_tag="LP386_001544"
     CDS             30613..31611
                     /locus_tag="LP386_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HBL1918783.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            31645..32580
                     /gene="whiA"
                     /locus_tag="LP386_001545"
     CDS             31645..32580
                     /gene="whiA"
                     /locus_tag="LP386_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HBL1918784.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            33123..33773
                     /locus_tag="LP386_001546"
     CDS             33123..33773
                     /locus_tag="LP386_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918785.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            33960..>34520
                     /locus_tag="LP386_001547"
     CDS             33960..>34520
                     /locus_tag="LP386_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HBL1918786.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
BASE COUNT        11452 a         5833 c         7323 g         9912 t
ORIGIN      
        1 aaatcagggg ttgcgggatt tttttgtttt cattaagacg tattacctaa gagttccatg
       61 actttagtct tgcggcgtgt cagctaacca aaaaagagaa aaagaaaagt aaaaaattcg
      121 actttctttt ttctagtagt atataaattt ttgcatatag ataaagatca agataccgat
      181 aacggaagct agattgtaat ctattttagt gacagtcagg tatagccaag taactagaag
      241 atcagtggaa cctgcaccat aaaagtttga gtttgtcggt ccgttgacag ttaaaagaaa
      301 aatcacgttg aagttattga tatttccgat tacgccgctt cgatttggtc acgatccaaa
      361 ttttggataa tccctgtaga aattagcata gtagctggga taccaattca catattgaca
      421 aagataacag agacttttac ataaaacgga tcaatcagga aaggaattgc tcgatccagc
      481 cccagttttc cagcaatgtg ttaactggcc cagcgtcatt cagcaaatta tgcatgatga
      541 ggagcgaaat gaactgcgga acagccattg tgataacgac aagttttttg gatcaatgta
      601 aaaaacgtca gcgaaaggaa aaatttcgtg gttttttata cctgttcatt tggctagata
      661 taaaatccaa acaaatgaac agaagtgctt attaggtttc aattgggagt atctgcgcta
      721 gaataagagt aataatgaaa aggagtgtta tgtatggatt attctagtaa agaatacttt
      781 gataaaatga cggcttggtg gcgtgctgct aattatcttt ctgttgggca actttatctt
      841 aaagataacc ccttactgag acgtacactg aaacccgaag atgtcaaaaa acatccaatc
      901 ggtcattggg gaacgattcc tggccaaaat tttatttatg tccatttgaa ccgagtcatc
      961 aataaatatg atttgaacat gttttatatt gaagggccag gacacggcgg acaagtcatg
     1021 gtatcgaatg cttatttaga tggaagttac acagagatct atccagaagt aacggaagat
     1081 gagacaggaa tgcaaaaatt attcaaacga ttttcatttc ctggaggcat tgcttctcat
     1141 gcagcaccag aaacaccagg ttctatccat gaaggcggag agcttggata ctctctttca
     1201 catgcagtcg gagctgtatt agacaatcct gaagtaatct ctgctgtcgt gattggtgat
     1261 ggtgaagcag aaaccggtcc tttagctgga agctggttct caaatgtctt tatcaatcca
     1321 gtgatagatg gagctgtttt accgatcctt catttaaatg gtgcaaaaat agccaaccca
     1381 acgatcttgg cacgtaaatc agatggagaa ttagcaaatt actttaacgg acttggctgg
     1441 gaacctttct ttattgaagg aaatgattca gaaaaattaa atcctgttat ggctgaaaaa
     1501 atggatcaag caatcgagaa aattaaatcc atccaaaaag aagctcgcct gaagacagca
     1561 acagatgtcg tgatgccaaa atggccagta ttgatcgtac gcacaccaaa aggatggacc
     1621 ggtccaaaag aatgggacgg ggaaccaatt gaaggaacct tccgagcaca ccaagtaccg
     1681 attcctgtag atcaagaaca tatggatcat gcagatgctt tactccgttg gctgaaatcc
     1741 tatgaaccag aaaaattatt tgatgcacaa ggacgtattt tagaagaaat cagagaaatc
     1801 gcgcctactg gtgaccaaag aatggcaaaa aatcctatca ccaatggtgg aatcgatcca
     1861 agaccgctta ttatgccaga ttggaaaaaa tatactttgc aatttgaaaa accaggctcc
     1921 gttaaagcag aagatatgac cgaacttggt aaattcgttc gcgagatcat tgagaaaaat
     1981 ccagaaaatt tccgtatatt tggaccagat gaaacaaaat caaaccgatt gaatcaagtt
     2041 ttcaaaacga caaatcgcca atggatggaa aaaatcgaac cagaaaatga tgaatggctt
     2101 tcgccatctg gtcgcgtcat cgacagtcaa ttatcggaac accaagatga agggttctta
     2161 gaagggtacg ttctgactgg acggcatggt tttttgcaag ttacgaatca ttcttgcgag
     2221 tggttgactc tatgttgact cagcacttca aatggatgcg gaaatcacat gacctttctt
     2281 ggcgaaatga ttatccttcg ctaaatctca ttgcaagctc aacagtcttc cagcaagatc
     2341 acaatggata tagccaccaa gatccaggaa tattgacaca tttggcagaa aagaaggcgg
     2401 agttcatccg tgaatatctg cctgcggatg caaatacatt gctcgcagtc atggataaag
     2461 cattccgctc gtcagaaaaa atcaatttga tcatctcttc caaacatccg cgtgctcaat
     2521 tttactcagc agaagaagca gccgtcttag tgaatgaagg cttgaaaatc attgattggg
     2581 cttcgacagc aaaagaggag gaacctgaat tggtcattgc tgctgcagga acggaatcta
     2641 acttagaagc attagcagct gtaactttgc tgctggaaga attcccaaaa ctaaaaattc
     2701 ggttcatcaa tgtcgtagat ttattgaaat tacgtcatcc aagtcaagat ccgcgtgggt
     2761 tgagcgatga agaatttgat caatatttta caaaagacaa accgatctta tttgctttcc
     2821 acggttatga aacattggtc cgcacgattt tctttgatcg tcataaccat catttaatga
     2881 ttcatggcta caaagaaaat ggagatatca cgacaccatt tgacatgcgt gtagtaaatg
     2941 aacttgatcg ttatcatttg gcaaaagacg cagctttaaa aatcaaagga agtcaagcag
     3001 aagattttgc gaaaaaaatg gatcagaaat tacaagaaca tcaaaactat attcgtgaaa
     3061 atggtattga tctgccagaa gtattggatt ggaaatggaa aaatcttgac caataaaatg
     3121 ataaaatcga tcccgcaaaa tagaattttt tacattgatt aagaaactga aaaaataaat
     3181 aaaaaaaacg gaaaaaagac tggaagaatg gccagtcttt tttttcgttt ttgggaagtg
     3241 aaaaccaaac tatttacctg taagccaccc ataaatccaa tcaaatggtg caaagaaaaa
     3301 atcttccatt ctattccctc ctttaaaaaa gcataacatg atttctattt acgtgagcat
     3361 gaattttgtt acgtttttat tgccgaaaaa taaaaaccgt tcattatgat gtcaaattcg
     3421 tcagtaattg atgcaatgtg ttataataat tcagttaaat caaaaatgaa atggagaaaa
     3481 gacatggacg ggttattacc tttatggaaa gaacgcggaa tgacaagtca tgattgcgta
     3541 ttcaaattaa gaaaaatctt acatacgaaa aaaatcggac atgggggtac gcttgaccca
     3601 gacgtagacg gtgtgttgcc catttgtatt ggaaaagcca caaaagttat cgaatatttg
     3661 acagattctg ggaaaatcta tgtaggcgag ataactctag gtttcagtac aacgacggaa
     3721 gatcgatccg gagaacgggt agaaacaaaa ccagtagata tgtctttatc tgaaaaaaaa
     3781 atagatgaag tgatggcttc atttattggt gagatcaccc agataccacc aatgtactca
     3841 gcggtaaaag tcaacggtaa gcggttatat gaatatgccc gcaataatga aacagtggag
     3901 cgtcctgtta gaaaggctca gatttaccgt tttatccgga caagtgaatt gacaagagac
     3961 gaagtgacag gaaccatttc ttggcgcttc gaagtagaat gcgggaaagg aacctatgtc
     4021 cgcacattag ctgtagatac aggcaagaaa cttggttacc ctgcgcacat gtctgatctg
     4081 acccgaacag caagtgccgg tatgtcccag aaggatgctc tgacattaga agaagtagct
     4141 caagctgtga aaaatgggac aatcgatgat tgtttgctgc caatagaaaa aggagtggaa
     4201 cggttcaaac gagtagatat tactgatgaa gtatggcaga aagtaaaaaa cggtatgaga
     4261 cttgattata ctgtatttgc gctcccagaa atgccgtcag aagaaattgc tttgttttat
     4321 aaaggaaaag ttgtcagtat ttatcagcca aacccgaaag aaaaaaacaa attaaaacct
     4381 agtaaagtat tgagaaatga ggaataacga atgaatatca tcaagatcag acatccttac
     4441 caatcagaac aaattccaga agacgatgtc gttttagtgc tgggattttt cgacggcgtg
     4501 catatcggac accagaaagt cataaagaca ggtatggaaa ttgcacaaaa agaaggattg
     4561 aaattagcat tgatgacttt caatcagcat ccatctattg tctttaaaaa gatcgatcct
     4621 agcagcgtga aatatttgac tagccttaag caaaaagaag aaaaaatggc cgctttgggt
     4681 atagattatt tatatgaagt tgattttact tcttcttttg ctcatttagc accgcaggaa
     4741 tttgttgatc aatacatcgt agggttacat gcaaaatatg ctgtttccgg ttttgattat
     4801 acgtatggac caaaagacat tgcagatgtc gctcattttc ctgaatatgc caaaggaaga
     4861 ttcaaaatcg tcacagtttc taaagaagaa gaacaaggtg aaaaaatcag ctctacccgt
     4921 attcgtggat tactagacag cggacaagta aaagaagcag caaaactatt aggttgcaca
     4981 tatgaggtag aaggggtagt tgtccatggc gatgcacgag gcagactact aggattccct
     5041 acagcaaatg tcaaagtaaa gagcacggtt catttgccta aagaaggtgt ttatgtgtcg
     5101 gaaataaaaa ttggggaaac atggtatcca gccatgggtt caattggaca taatgataca
     5161 ttcggtgaag gacgggagct gactgtagag ttgtatattt tggactttaa tcaagatatc
     5221 tatggtgaac atgtcgcggt acgctggaat caatttttaa gagatcaagt gaaattttct
     5281 agtgtagagg aattgattga acaactcaag gaggatgaac aagcaacagc tgaatatttt
     5341 tctcagcaat aaaacattat gcataaaatc tcttgtttat gtataactag caattacaat
     5401 aaaatgggtg ataaataagc ccaggaaagg ggctgtgaca aaagtcttgt cacagccttt
     5461 ttttccaaat aaatggtttt tcagaagtag cttcttcgga aataagccga aatttcttga
     5521 agctgaccac ttctgtcaca acctctttct ttatagaaat aaaaggacac tagcaattca
     5581 tgaaaacgat tgctagagcg tatcatttgc tttagactat atatcttggt gtacactcac
     5641 tttaaggcgg aaataaaagt tatccgtaat aacaggttta ggtatgaaaa aggagtgggt
     5701 actatgtaca aggaattaga aaacaaagtc gcagtagtaa ctggtggctc aaaggggatt
     5761 ggaacagcga ttgctcaacg attcgggaaa gaaaaaatga atgtagttgt caactataac
     5821 tcggataaag aaggagcaga aaaagcagtc aaagcaatcg aagaggcagg cggaaaagca
     5881 gtctctgtac aagcagatgt cagttctgaa gaaggaatac agcgtttact tgatacggct
     5941 ttagaaaatt ttgggacact ggacgtttgg gttaataatg ctgggatgga aaatcagcat
     6001 ccaacccatg aacttagcct tgaagattgg gaaagagtgt taaaagtcaa tttgactggc
     6061 gtttttatcg gaacgaaagc ggctttaaat tactttacag agaataataa aaaaggaaat
     6121 atcatcaata tgtcttctgt tcatgaacag atcccatggc caacgtttgc tcattacgct
     6181 gcttcaaaag gcggggtaaa attatttacc gaaacggtag caatggagta tgcaccgaag
     6241 ggaatcagaa tcaatagtat aggccctggt gctatccgta cacctattaa tgcggcaaaa
     6301 tttgatgatc ctgaacaaaa agaactcttg gaaagtatga tcccactagg acgcgtaggt
     6361 gaaccaaaag aaatagcggc gacagctgca tggttggctt cagacgaatc cagttatgtt
     6421 acaggtatta cactatttgc agatggtggg atgactttat atccttcttt ccaaggtgga
     6481 aaaggataag ggtgaataaa aatgggttta ttgattgcat tgatcccggc agttggctgg
     6541 gggatccagc cactgatttt gaaaaagatt ggtggcagac caacaaatga gatattagga
     6601 actggtattg gagcggtgct tgtcggctta ctcgttcaat tattcgcttc tccagctggt
     6661 atttcagtga ctacattttt gattagttta ctttctggtg cattttgggt tattggacaa
     6721 acaggacagt atacatcttt caacttgatt ggtgtttcta aaacgatgcc aatttcgact
     6781 gcattacagt tagtcggaac ctcgttgatt ggtgtcttcg cttttggaga atggtctgga
     6841 agtatgggga aaatcattgg agcagcagca atcattcttc ttgtatttgg ttctgcttta
     6901 acggcaatca gtgatgatcc tggaaaaaaa ggcggtatca caaaaggaat tagtctatta
     6961 gcatcaacaa gtattggtta ttgggtatac agtgcattgc ctaaactagt tgatgcaagc
     7021 ggactttcca ttttctttcc gcaaatgatc ggtgtctttt taggggcagt gatttatgtg
     7081 attttccgta aaccaaccgc attttctgaa gacaagagtt ggaaagcaac gatcgttgga
     7141 gccatcttta gtgtgtcagc attggcttat attttttcag caaatgaaaa tggggttgct
     7201 actgcatata tcattacaca gctaaacgta gttatctcta cattaggcgg tatgtacatc
     7261 ctgcatgaaa ataagacacc aaaagaaaaa aaattaacga ttatcggatt attgctgatc
     7321 gtagtaggaa gcatggtcac ggtctttatt tgaggataaa gatggtaaaa tttcatttat
     7381 taaaaaaata tttgtttgaa ccaaacagta agtacttata aaaaaatagc gctagaattt
     7441 ccaacatctc tggaatttct agcgcttttt aattgtttaa gatacaaggg aaatatctgt
     7501 ctggatcaat aatttttcat tgatccattg actaaagttt acgacataat tgaagttacc
     7561 accgattagt atctccgcat gattgtcttt ataaagatcg tattgtaaaa gacggtcttt
     7621 tttatttgcg taaacatcgt tatggtactg gactaattgt tctcggaatt gattgattgc
     7681 tgtaaaatca cgatattgaa ggttgaaacg catcgtgatt ggtgcattta gcatgaatcg
     7741 ctgcatttct tttgctgctt cctctgcttg atctccgtat aggaactcaa aaagattacg
     7801 ttcagaaaat ttccattgcc cgccaacctt tgttcctttt agttttcctt catgaagata
     7861 atttctgata gaacgtgtag taacacctaa ttgttcggct aattcattta ctgagtaaaa
     7921 atctttcaat gttcaccctc ctatgtgaat ggttctactg acttagttga tatttgctta
     7981 atcacgaaat gtagaaagaa cgattttaat taaggtcatt gtaaaaatca agtcagaaaa
     8041 ttctaacttt tatttctcta aagaaattcg ttctctccta aagtgatatt atatttaaat
     8101 atacctgaaa ataatgggca gtattatgaa agatcactga tattttctcg tattttttcc
     8161 ttattcaaaa gttttgcagg aaaattgctg aaaaaataat tttactaagt agaaaattca
     8221 aagccattca atcagtgatt tttttcagca caagaaagac tccttataaa aatagcagat
     8281 actttgtcaa ttaagtgttt aaccagggat gataaaaagg ataggattga acaaaacctg
     8341 tataaggtga tgaatagttt cctcgccagt aaaaggttta ttcgtataaa gctttatcgc
     8401 caaaatttat catgaccttt tttatcttca atattaaatg aaatcaattg ttcaatcaat
     8461 tcccagttga ttacactttt ccaaggaact ttgatgacgt tatccgtata tacgtagcct
     8521 gcttcttgga tatttttttc aagggcacga atcgctgctt tttccggtgc gatagaaaaa
     8581 tgatttttag caaaactaaa tgcaataata aaggtaccat ggtcagtaaa cataggttgg
     8641 ttccatttta cagttgtgtc tagctgggga tacgtttctg ttatcttagc aaaaaggtct
     8701 ttgatctttt gttgatgttc tttttctttg atttgattga tgatcggctg aaatttttcc
     8761 attctaaaac gcctccatta agtggtttga tttattttac cagaaaaaca atagttatgt
     8821 ataaaaaacg aacaaaacac aagtaatgtt gtaaccgcta tatttatatg ataagatgtc
     8881 tcaaataata aaatagaaaa gagacataaa aatgattgac ttggcaaaga aattcttaca
     8941 cgaaaatata tattttgagt tgtatcatca tcgagccatt tatacaaatg aagatgcttt
     9001 ggtaataaag aaagaacaag gatttacagg tacagagacc aaaagcttat tcttaaaaga
     9061 taaaaaagat aataactacg tatatctgac ttttactacg aaacaaacgg atttcaaagc
     9121 attagggaag atcgtcggta aaaggctttc tattgtttca tcagaacgca tggaagaaca
     9181 aacgggacaa aagcagggcg ctgtttctcc gtttggttat gaaaaacaga ttccgattat
     9241 tattgatgaa gagctcttat caaatgaaaa acttgttttt gcaccaggta gaccagatca
     9301 aacgatggtc atccaaacgg ttgacttaaa caaaatcatc cagctacttg agatgccgat
     9361 atttttgatg ccggcaaacg aaaaaaacaa ttaaccaagt aaaatagtgc atacttggag
     9421 gtgaagcaac atgataagtt atccattatt agaaagaaat gcaacgattg gggttactgc
     9481 accatcctca ggcgtatcag aggaacacca ttcgttactc gaatcagctt taaagagaat
     9541 ggaagaaaaa tctttccaag tagttactgg aaagacgctt tggacgcaag ataaggaaaa
     9601 atcaggtcca gcaagaaaac gagcagatga attcaatcaa atgatgcaag atgaaaatat
     9661 ccaaatgatc tttccgactt ggggaggaga attattgatt gagattctcg attttgtcga
     9721 ttttgatgct ctacaaccaa aatggatagt aggttattca gatattagta cgttgctact
     9781 tgctgtcaca ttaaaaacag ggatagccac tgcacatgga actaacctta ttgatttaag
     9841 aggagagtac ttggatgaaa cgacagcaat gtgggaaagt gtactgaaaa caagagaagg
     9901 agaatcgatt ctacagcaat cttctgaaaa gtatcaaaaa gtgtggcccc atgagcattc
     9961 atcatcttct gttttccatc tcactgaacc aacaaattgg caatcagtca gcggagatgc
    10021 agtaaggatg aagggacgat tattaggtgg ttgtattgat acgatcaggc atttaatcgg
    10081 tactccttat ggagatgtcc aatcttttaa aagaaagtat aatgatggaa agccgatctt
    10141 gtggtttcta gaaaactgtg agctatcgtc agttgattta agaagatcac ttgttcagat
    10201 gaaactggca ggctggtttg atggcagctc ggggatcatg ttcggtagaa gtgcggcaga
    10261 ggatttgtta gattataaaa tgaaggatgt atacgaagat ctgtcaaagg aattaaaact
    10321 accgatcttg tatgatattg attgtggtca tgtaccgcca caactgacat tgattaatgg
    10381 tgcctatgca gaagtagcgg tagaagatag aaaagcgact gttttgcaaa cgtttattta
    10441 aaaaattttt tcctgccttg gagtctatca aagaccaata aatctaaata gaaaagaaag
    10501 tgaaagaagc tgacaaaatg ctgtcagctt ctttttgtat aacatattag aaagtctaat
    10561 tatctataac tgtcacatcg attaactgtt tcacgtcatt gggatttcct gtaggaatag
    10621 ctactacaga tgcattatca atgatttctt gagttgtttc tctaatgaac gctggataag
    10681 atgtttgatc tgcaggcatt tgccaatgtg aaggaactgg ataactagtg attgtcccgt
    10741 catggttact tgaatacact aaaactccct ggtaactgta tttcccagtg agcataacca
    10801 catctttcgg atagactgca ctccctgcat cataaggggc gataggtgtt cctgcaggat
    10861 aatgaataac atgtaattcg aaatcacccg atgtatctct aaaagtatta cctctaatag
    10921 ctagccaaac acgtgcgtac tcaatttgta gatcagaata tcctgctaac ggatctattg
    10981 actgagaaga ctgtgaggag gttgtgtcta ttgttgaaga agaaatattt gtctcaactg
    11041 tactactaga tgtagaagaa gtattgggct ctgagacttt actgcttgtt gaagatgtat
    11101 tcgtttcagt agaagctgat ttctgagtac ttgatttttc agctgaactg gtttgtctga
    11161 ttgaactttt gtctgtggtc gcagatggat cactattttc tttactagga gacgtacatc
    11221 ctacaaggaa taaagagacc aacaataaaa taaaacctaa ctttttcata taaaatacct
    11281 cattattttt ttaataccag tatagcataa tcctgaattt ttgaatccgt aaaaccttgt
    11341 ctatgaatat aaatagagtg tatcttcttt gataaatgtc agaaaaagtg tgacaaataa
    11401 tcatcagtaa aattacttgt cacactattg ataaggagta tttaattgaa gagaatgatt
    11461 aggagaaagg atctccgtac tttttatagt aatcatagaa tccaagtttg tatagacgaa
    11521 tcgttttttc tcttatttct tctgtttcaa aatggactgc ttgaagaatc aagtctgtga
    11581 attctatagg agctgttcca ttcgcagtaa tcaaattacg atctttcaca gcttgttgtt
    11641 ctataaaatc ttctttattc tgataatttt ccgattctaa ccaaggaaat tgcgcatttc
    11701 cggtgtgttt gtaaccttgc aataatccgc tctgagctaa ataatcaact gccccacaaa
    11761 tagcagctac tggtacgtct gtttttaaca atttatcgat tatttgatat aaatgatgat
    11821 tttttatgtc ccatgaattg ccaccgatca taataaaaag gtcaactttt tcaggtattt
    11881 gttcgattaa gtaatcgatt tttgttttta atcctccaat ggaagtgacc tctgattgga
    11941 tagaagcagt tttgttttgc catttctcat tttggtttag tgtgctagta atataagcac
    12001 cttcccaatc ggcatattcc tctaatagaa acgtaatcgc agttttcatt ttcaagctct
    12061 cctttactat ctataacaag gacaacagtt ttaacctaca gacattcatt aaaattgggt
    12121 agcgacagcg aaaacaacaa ttcttaagtt ttagacagag tatacagata gtcaacttaa
    12181 ttaaatacga actaaataaa aatgacaggt aatcattttt gtttaccagc attataacat
    12241 tttgcataca tggatgacaa aagaaccaat tcccacttgc ttgagtacaa tattaaaaga
    12301 aactggaagg caaaaagtaa ttatagaaac gaaaaataaa tcatatcggg cactcagaca
    12361 tgaaaacaac cctagagata tataactagg taaccagttt aatgaaagaa aaaatcatcc
    12421 aagaagtcga ttcttggatt ttttagtgga tttgttcgcc aaatacgttt agtatgcgta
    12481 tatgagaggt tgtaagcaaa gcgttgtggt ctgagcactt aaggaggaat ctgtgaaaat
    12541 agcttttcat atttttgcag attttgactt aatgccgaag gtcagctttg cgattaccgt
    12601 ttatcgagag gctgtaaaag caccgtgtag ctccgatgac aataagcaag catttttaga
    12661 gctaggtttc cttgattcta aatatgcggc ttatttcaat gagttggtgc ttgaacgcga
    12721 ttttaagaag gtcgaaaaca ggcacgactt ttcgacgtaa ggagaaagaa tttcaatgat
    12781 agaaacaata aatcccgcag aaaacaaggt ttctgcgtac attcatatcc cattttgcga
    12841 gcatatctgc tattactgtg attttaataa agttttttta gaagggcagc cagtagatga
    12901 gtatgtggaa atgctgctga atgaaatgaa aataatgcta gaaagtcatc cgacagcgaa
    12961 tttagaaaca ctttacgtag ggggcgggac accaacttct ttatctgcta aacaacttga
    13021 tcgactgtta tcaggtgcta gagagatcct gccttttcaa aatggtaatg agtttactgt
    13081 agaagcgaat ccaggtgatt tgacccgtga aaaacttcaa gtaatgaaaa actatggcgt
    13141 caatcgttta tccatgggag tgcagacatt tgataatcgc ttattgaaaa aaattggacg
    13201 taaacacacc gcagaagatg tgtatcaaac tatgcaattt ttagaagcag aaaattttac
    13261 caatgtaagc atcgatttga tttatgcatt accgggacaa acactagaag gatatctgga
    13321 tactttggaa aaagctttgg ctttggatct gcctcactat tctttgtact cattgatcct
    13381 cgaaaacaaa acaatgttca tgaactgggt acgacaagga agactcgaac tgcctgatca
    13441 ggaaacggaa accagaatgt ttgaagagac gattgaagca atggaaaagc atggacgtca
    13501 ccaatatgaa ataagtaact ttgggctctc cggacatgaa tctcaacata acctcatgta
    13561 ctggaacaat gaccactatt ttgggtttgg agctggtgct agcggttatc ttggagatat
    13621 tcgttaccgc aacaaaggac caatccaaca ctatttacgc ccattacgag caaatgaacg
    13681 cccggtattg gaagaagaaa aattgacacg aaaaaatcaa atagaagaag aaatgttctt
    13741 aggactaaga aaaaaaacag ggattactaa aaaacatttc tatgatcgct atcaaaaaac
    13801 aattgaatcg gtgtacggtg atgtgctaag ggaattagag caagaagggt tacttgttaa
    13861 tgaagaagac cgtgtttatt tgacaccaag agggaccttt ttggggaaca atgtgtttga
    13921 gcgctttttg tttgaaaaat agtttaaaga atatttgttt tttatctgaa tttaaataaa
    13981 aaaagttcaa aaatacaata aaggactatt gaaacgttga tataactgga tttacatcaa
    14041 ttatttagaa ttagcactct tgtgtttaga gtgctaaaaa atggagtctt tctcttgaca
    14101 ggagaagggc ttcttgctat atttataagt ggattagcac ttagaatata tgagtgctaa
    14161 tgagaggtga ggaagatgtt aacaaagcga caaaacgaca ttttacgtct gatcatccaa
    14221 cactatacga gtagtggcgt gcccgttggt tccaaaacat tgatgtctga gggagtcaag
    14281 gccagctcag caacgattcg caatgatatg aaagcattag aagatgaagg attgctgttg
    14341 aagactcact cttcttctgg gcggattcca tctgctttag gctatcgtta ttacgtggat
    14401 catttgttaa aacctgctcg cgtagcagaa gatgatttgc tgctgattcg tcagtctcta
    14461 ggcagagaat ttcatgaaat caatgagatt attaagcaat ctgctgagat attatctgag
    14521 ctgacaagct atacgacttt ttcattggga cctgaaataa aagaccgccg actgactggc
    14581 tttcgtatcg tacccttgaa taatcgacag attattgcta tcgtcgtaac agatatgggg
    14641 aatgtagaaa gccaagtgtt cactcttccc gaatatatgg gaagtcagga actagaaaaa
    14701 atggtacaga ttgtaaacga ccgtctagtc ggagatcctc tgatgacggt gtaccataaa
    14761 cttcgtacgg agattccgat gattcttcat aaatatttcc aaacgacaga agggatgtct
    14821 cagttatttg acaccgttct tggtcatgtt tttgaagata aggtttatgt cagtggacaa
    14881 atgaatctct tggattatga gccccgtcaa gatcttgatc agttcaaatc gatgttttct
    14941 tttatgaaag actcagacgg acttacacaa atgatcactc cgatggatag caatattcat
    15001 atcaagattg gtgctgaatt aggcaatgat ttattgcaga atatgagtat gattcaagca
    15061 agttacgaga tagatggtca tggaagaggt acaatagcct tgttagggcc tactagtatg
    15121 ccttattctc ggatgttcgg tctagtcgat gtttatcgaa gagaactagc agctaaactt
    15181 gctgattact accgttcgct tgacttgtca aactcgtaat gtgaataacg aagctatttg
    15241 cagctgatcg ttctctcttt cttagtaaga gcaatcaaac agctgactga ataatgaaag
    15301 gaagactgta tcgtgaaaga aaatcaagaa gaactagata aagaaatgac agatgctcag
    15361 ccagaaccgg aaatcgatgt cgaagctgca gaagattcgg gtatttcaga agctgaagcg
    15421 gaagaattcg aaacagcgaa attaaaagct gagttagaag aaatggaaga taaatacttg
    15481 cgggctcgtg ctgaaatcgc aaatatggca aatcgaggaa aaaatgagcg tgagcaatta
    15541 caaaaatacc gttcacaaga tttagccaaa aaattacttc catcaattga caacctggaa
    15601 cgtgcattag ccacagaagt gtcagatgat caaggggcag gtttgaaaaa aggcgtggaa
    15661 atggtcttgg aaagtttgcg taacgcactg gaagaagaag gaattgaaaa aatccctgct
    15721 aaaggagaag cctttgatcc taatcttcat caagcagtac aaactgttcc agcgactgaa
    15781 gatacaccag ccgatacgat tgtagaagta ctacaagaag gctacaaatt acatgatcgc
    15841 gtgttaagac caaccatggt cattgttgca caataattgt gcggatataa aacttacact
    15901 ttcaattaaa gaaggagacg ttaattatga gtaaaattat cggtattgac ttaggtacga
    15961 ctaactctgc agtagcagta ttggaaggaa acgaagcaaa aatcatcgct aacccagaag
    16021 gaaaccgtac aacaccttct gttgtatcat tcaaaaatgg agaaatccaa gtaggggaag
    16081 ttgcaaaacg tcaagctgtg acaaacccaa atacgatttc atcaatcaaa cgccatatcg
    16141 gtgaagcagg ttacaaagta gatgtagaag gtaaatcata tacaccacaa gaaatctcag
    16201 caatgatcct tcaatatatc aaaggattcg cagaagacta tttaggtgaa aaagtcgaaa
    16261 aagcagttat cactgtgcca gcttacttta atgatgcaca acgtcaagca acaaaagatg
    16321 ctggtaagat cgctggtcta gaagtagaac gtatcgtcaa tgaaccaact gcagctgctc
    16381 ttgcctatgg tttagataaa acagatcgcg acgaaaaaat cttagtattc gaccttggtg
    16441 gcggtacttt tgacgtatct atccttgaac taggagacgg tgtctttgat gtattgtcaa
    16501 cagctggcga caaccatcta ggtggggacg actttgataa caaaatcatc gactacatgg
    16561 tagcagaatt caaaaaagaa aacagcattg acttgtctca agacaaaatg gctttacaac
    16621 gcttgaaaga cgctgctgaa aaagcgaaaa aagatttatc tggcgtatca agcacacaaa
    16681 tcagcttgcc atttatcaca gcaggagaat ctggaccatt gcatttggaa atgacattga
    16741 cacgtgcaaa atttgatgaa ttaacagctg acttagtaga acgtacaaaa gtaccagtac
    16801 gtcaagcgct aaaagatgca ggtttatcac aatcagaaat cgacgaagtt attttagtcg
    16861 gtggatctac tcgtatccct gcagttgtag aagcagtacg taaagaaaca ggaaaagaac
    16921 caaacaaatc agttaaccct gatgaagtag ttgctatggg tgctgctatc caaggtggcg
    16981 tgatcactgg tgatgtgaaa gatgttgttt tacttgacgt tacaccattg tcattaggta
    17041 tcgaaacaat gggtggagtg ttcactaaat tgattgaccg caatacaacg attccaacaa
    17101 gtaaatcaca agtattctca actgcggcag ataatcaacc agcagtagac atccatgtat
    17161 tacaaggtga acgcccaatg gctgctgaca acaaaactct aggaagattc caattgacag
    17221 atattccagc agctcctcgt ggtattccac aaatcgaagt aacattcgat attgataaaa
    17281 acgggattgt aaatgtatct gcgaaagatc taggcacaca aaaagaacaa aaaatcacga
    17341 tcaaatcttc ttcaggtcta acagacgaag aaatcgaacg tatggtaaaa gatgcagaag
    17401 caaatgcaga agcagataaa gctcgtaaag aggaagttga cctacgtaat gatgtagatg
    17461 cattgctatt ctctgtggac aaaacattga aagaattaga aggcaaagtg gacgaagaag
    17521 aagtgaaaaa agcagaaaca gctcgcgatg aattgaaagc cgctgttgaa gcaaacaaca
    17581 tcgaagaaat gaaaactaaa cgcgatgcat tgaacgaaat cgttcaaaac ttgactgtta
    17641 aactatacga acaagcggca caacaacaag ctcaagaaaa cccagaagca gctcaaggcg
    17701 gagcagatga tgtcgttgat gctgattttg aagaagtcga tggcgacgat aaataatcag
    17761 ttcactgaat ttcgagagaa ggccaaagtt gctactttgg ctttttcttt tgaaaaatag
    17821 tttgaagtat cggtttttgt ttcaaacaaa atatgatatg ataacaagcg acgtgaaaat
    17881 gatgagaacc aataggagga aagcctatgg caacaaaacg tgattattat gaagtcttag
    17941 ggctctcaaa aggagcatca gaagatgaaa taaagaaagc ttatcgtaag ctttcgaaaa
    18001 aataccatcc tgacatcaat aaagaacctg atgcggaaga aaaattcaaa gaagtatcag
    18061 aagcatatga gattttaagt gacccgcaaa aacgcgctgc atatgaccaa tacgggcatg
    18121 caggcacaga tccaaattac ggtgctggtg gagctggtgg cggatttggt ggattcggcg
    18181 gcttctctgg tggcggcttc ggtggttttg aagatatctt cgactctttc tttggaggag
    18241 gcggtcggtc agtcgatcca aatgcgcctc gtcaaggtgc tgatttgcaa tatacggtcg
    18301 acttgtcttt tgaagaagcg atttttggtg tagaaaaaga aatcaagtat aatcgggaag
    18361 aaatctgtca tacttgtggt gggaacggtg caaaaccagg cacacaacca actacttgtc
    18421 ataaatgtca tggtgcaggt acgattaatg tagaacgcca aacaccactt ggacgagtga
    18481 tgagccgtca aacttgtgat gtttgtcatg ggacagggaa agaaatcaaa gaaccttgtc
    18541 caacctgtca tggctcagga catgagaaga aagcacattc agttaaagtg aatgtaccag
    18601 ctggtgtaga agaaggacaa caaatgcgtt tagctggtca aggagaagct ggagaaaacg
    18661 gcggaccatt tggtgatttg tatgtggtct tccgtgtaga agaaagtgat atctttgatc
    18721 gtgaaggttc tgaaatttac tatgaattgc ctttaagttt tgtacaagca gctttggggg
    18781 atgaagtcca agtaccaact gtccatggag atgtgaaatt gaagatccct gctggaacac
    18841 agacaggtac gaacttccgt ttacgtggaa aaggcgctcc gaagttacgt ggtggtgcaa
    18901 caggcgacca acatgtcaaa gtaaaactga tcacaccgaa aaatctaaat gaacaacaaa
    18961 gagaagcatt acgtgcattc gctgaagctg gcggcatcaa agttgaagaa cagcaagaag
    19021 acggtttctt cgataagttt aaagatgctt ttggcgggaa aaagcggaag tagtttttct
    19081 agtaaaaacg ctaagtcatt aataattaaa aaccagacga acaatcatat gttcgcctgg
    19141 tttttttgta gttgtcatgt ttgtaccaac aaaaaagcca gctttagaat atgataatcg
    19201 tcatagtttc taggggtata accagtgaga gaatggaact tgttcaatcg atattgcaag
    19261 gtgtttttat gaataaataa ttcttctgag caatttttga tgcttccgtt atttttactg
    19321 aagcatgcca aagtcttctt gaacaaatgt acttcttctt ctgtcaggct tttcaaaata
    19381 cgttttacat ataatgttcg ttgatctgac gggattgctg gtaaaacgat cccgaggtct
    19441 aaatcttcaa aaaagcggat ctcgttcaca gattgatgga aagctatcca ttcgcaaact
    19501 tgtttggcat gaaggaaaga ttgcggtgtc tcttgctctg tataacaaag cgacccaatt
    19561 ccaaagttta gctgtaactg atacatttta ttaaactttg tctggatttt atcaagcaat
    19621 gatagcaatg aggctctgga aatccgattg actaggataa tgatttgttg tctatgtaca
    19681 gtgagcaaag cctgtccgta ataagagaag accctttcga gcaactccaa taaaggattg
    19741 atccgttctt gacacaattg ctgattgtca gaaagttgtc ccacaactac ataatatgga
    19801 gaagaaaaat caagctcaat taagtgaggg tggtatcgac tatgtacttg atatcatcaa
    19861 tgaaccgatg gtactttctt atgcgatgga acaggtagag cgattgcttg tttgtgcagg
    19921 aaaacaagcg atgcggctga tacgattagg tgagaaaata agaagataaa aatacacggt
    19981 cccttcatgg cgaccgtgca tttttggttt ttattaaata tttaatactt tattcaagaa
    20041 atcttttgtc cgttcatttt gcggattttc aaagatttgt tgaggcgttc catcttctaa
    20101 aaagtttccg tcgtcaatga acatgacgcg attggccact tctttagcga accccatttc
    20161 gtgcgtaacg ataaccatcg tcataccttg ttctgctaac tttttcatga cgttcaagac
    20221 atcaccgacc atttcaggat cgagtgcaga agtaggctca tcaaaaagca tgatgtcagg
    20281 gttcatcgct agagcacgag caatagccac acgctgtttt tgtccaccag aaagcatttc
    20341 aggatacata tcttttttat cttctagacc aactgtctgc agtaatttga ttgctttttt
    20401 ctctgcttct tctctagatt ctttcttcag gtccatcggt gctaaaatga tgttttccaa
    20461 aatagaaaga tgagggaata ggttaaagtg ttggaatacc attccgatat gttgtctcac
    20521 caagttgata tctgtgcttt tatccatcaa gtgggcgccg tcaataataa tttcaccgtc
    20581 agaaggttct tctaaacgat tcaagcaacg caagaatgta ctttttcctg aacctgaagg
    20641 gccaatgata cagacgacat ctccttcgtt gatggataca ttgatgtcgt ttaatactgt
    20701 gttatcgccg tattttttga ctaaatgctc aactaagatt ttttctgcca tcttacttca
    20761 ccttcttttc taaaactttt gctaattttg tcaatgctgt gatcaaaatc aagtacatga
    20821 tcgcaatgat caagtaaaca tacgtacttt gtgttgtacg tgcaacaatg atcttaccag
    20881 tttgcagcaa ttcgactaca ccgattgcgg aaatgatcgt tgtgtctttt aatgagataa
    20941 cgaactgatt gacgaatgat gggatcatga tgcgtatcgc ttgcggcaaa atgatttttt
    21001 gcattgtccg attataagaa agacctaaac ttctggaagc ttccatttgt ccgacaggaa
    21061 cggcgttgat cccgcctcga acaatctctg cgatataagc acttgcgtta agagtcaagg
    21121 tgataacacc agcaaggaag tcaggaatcg taaatccaac gataccaggc aacccaaaga
    21181 aaataaagaa cgcaagaacc atcattggaa ttcctcggat gatatcgaca taaatactag
    21241 caattgtgcg aagagcgcgt attggtgcta cactgaataa tccaaaaatc acaccgatta
    21301 ctatagccaa agcaaaggag atcaaagtta ggagaattgt tctccaaagt cctttcaaca
    21361 atgcttgata gttgttttgg ataagtccaa gaaatgttga ttcatcagca gtggaagact
    21421 cactggaagt ttctgaacca tccgctacat attctttaat aatcttatcg tattcgcctg
    21481 ttctttttaa ttctttcaat ccttcattga acatattaag aagctcagga ttttgtcctt
    21541 ttttaacggc aaatgcatat tttccgccag attctttttt gatcggtgtt tccaattctt
    21601 gtccttgttt gatcgcataa ccgattaccg gataatcatc catcattgca tcgattgcgc
    21661 caacttttaa cccgtcgtac aattgatcag cagcatcaaa atatttgata gaatagccat
    21721 attcagattc atggtcgctt aaaaattcag cactttcggt accaactttt gctccgactg
    21781 tttttccttt caaatcttca taagacttga tcgaagtatc tccttttttg acagctaatt
    21841 ggatcccgct atcaaagtaa gaatcagaaa aatcatagct tttctttcgt tcatctgtta
    21901 cagtcattcc ggcaatcatt ccgtctgctt gtcctgattc caaagcttgc aaagcagcag
    21961 agaaaccacg gtagtccatt cggatgttaa atccttgcag tttggcgatg ttttccatca
    22021 attttacatc gatgccttcg tactcgccct ttgcgttttg aaattcaaat ggagcaaaag
    22081 cagagtcact ggcaattacg tatacgtctt ttttgggctc tattttttgc attgtctcgc
    22141 ttgtgcttga ctctgccgtt gtagtgttgt cagcttgtgc aacatgacca aacgcaagtg
    22201 tcacaagtcc tgtcattaag aaaacaaatg agtgaaataa atgctttctt ttcataatca
    22261 acctcctaaa tttccaatat tttattatta taggcgaaaa gtgctgaatc agacaagact
    22321 gtaagctcga aaaaatgaaa aaaatgcgag tttctaacat tttatgttat aaaacataac
    22381 atgtataata agataaaaaa gtggcgaaag tatgttcggt gtggtataat tttttagtaa
    22441 ggaatgcctt tgctttcctt ttctttttat tggtcgtaaa atgaaaagga atgaatgaaa
    22501 aggaggacga agaatgattg agagagatac ctcccgacac tttgagcttg tctcgaaata
    22561 ccaaccggct ggtgatcagc ctgaagcgat taaccaatta gtggatggcg tagtcggcgg
    22621 gaaaaaagca caaatcttat taggtgcgac tggaacaggg aaaacatata cgatttccaa
    22681 tcttattgag aaagtgaata aaccaacact gattattgcc cataacaaaa cattggctgg
    22741 tcagctgtac ggggaattca aggaattttt ccctaacaat gctgttgaat attttgtttc
    22801 ttattatgat tattatcagc ctgaagctta tgtgccttca agcgatacgt atatcgaaaa
    22861 agattcaagt gtaaatgatg agatcgacaa attacgacat tcggctacta gttcattatt
    22921 agaaagaaat gatgtgatcg tcattgcatc cgtttcatgt atttttggat taggctcgcc
    22981 ttttgagtac caaaaacaag tagtttcgat tcgacaggga gcagaactag atcgcaatca
    23041 gttgattcgt gacttagtca gtatccaatt cgaaagaaat gatatagatt ttcagcgcgg
    23101 tcgttttcga gtgcgcggtg atgtcgtgga gatttttccg gcttcaagag atgaacgtgc
    23161 cttacgtgtg gagttttttg gagatgaggt cgaacgtatc cgagaagtca atgcactgac
    23221 aggtgaagtt ttaggagaaa cggaacacgt agcaatcttc ccggcgactc actttgtgac
    23281 gaatgatgaa catatggagc atgccgtagc gaatatcaaa gaggaattag aacagcgttt
    23341 aactgtcttg cgaaatgaaa acaaacttct ggaagctcaa cgtttagaac agcgaaccaa
    23401 ttacgatatt gaaatgatgt tagaaatggg ctacacgtcg ggaattgaaa attattctcg
    23461 gcatatggac ggacgtaaag aaggtgaacc gccttatacg ctattggatt tctttcctga
    23521 agattttttg atcgtggcgg acgaatcgca cgtaaccatg cctcaaatca gaggaatgta
    23581 taatggtgac cgagcgagaa aacagatgct agtagattac ggtttccgtt tgccatctgc
    23641 tttagacaat cggccacttc ggttagaaga gtttgaaaaa catgtcaatc agatcattta
    23701 tgtctctgcg acgccaggac catatgaaca tgaacaaaca gataccgtta tccaacaaat
    23761 catccgtccg acagggctgc ttgacccagt gatcgaagtt cgtccaatca tgggacaaat
    23821 cgatgatcta gtaggcgaaa taaatgaacg agtcgaaaaa gaccagcggg tgtttgtaac
    23881 gacattgacg aaaaaaatgg cagaagacct cacagattat ttcaaagaat tagggatcaa
    23941 agtcaaatat ttgcatagtg atatcaaaac gctggaacga acagaaatca ttcgagatct
    24001 tcgattaggt gaatttgatg tgttagttgg aatcaatttg cttcgtgaag gattagacgt
    24061 acctgaagtt tcccttgttg ctatcttgga tgcggataaa gaaggctttt tacgtagtga
    24121 acgttcctta gtccaaacga ttggacgagc tgctcggaat gaagaaggta aagtaatcat
    24181 gtacgcagac aaagtaacag attctatgcg tctagcgatg gatgaaacgt caagacgtcg
    24241 tacgattcag cagaagtaca atgaagaaca tgggatcgtt ccaaaaacga tcattaaaga
    24301 aatccgagat ttgatttcta ttacgaaaga atcggaagat gatacaaaag aagcggtaca
    24361 agtctcgtac gaagaaatga cgaaggaaga aaaagacacg ttattgatga aattagaaaa
    24421 agaaatgaaa gatgcggcaa aagctttgga ttttgaaaca gccgcgaatg tgcgagatat
    24481 gattttagaa ttaaaagctt caaagtagga ggacaacatg gctaacgata aaattacgat
    24541 tcatggtgca cgtgcccata acttgaaaaa tatagatgta acgattccac gagataaatt
    24601 cgtggtcgtt acaggtttgt ccggttctgg aaaaagttcc ctagcatttg atacgctgta
    24661 cgctgaaggg cagcggagat acgtagagag cctttctgct tatgctcgtc agtttttagg
    24721 acaaatggat aagccggacg tagatagcat cgacggattg agtccggcga tttctattga
    24781 tcagaaaaca acaagtaaaa atcctcggtc gacagtaggt actgtgacgg aaatcaatga
    24841 ctatttacgc ttgttgtttg cacgtgtagg acatccgatt tgtcccaacg atcatatcga
    24901 gattaccagt caatcagtag atcaaatggc agatcaagta atggctttgc ctgagcgcac
    24961 aaagatccaa gtgttggcac cgatcgtggt aaagaaaaaa ggacaacata aaaaaatatt
    25021 cgaacgaatc caaaaagagg gatacgtccg cgttcgagtc gatggtgaga tctatgattt
    25081 aagtgaagtg cctgagctgg agaaaaacaa aaaacatgat atcgcgatcg tcatcgaccg
    25141 gatcattgtg aaagaaggga ttcgttctcg cctatttgat tctttagagg cggccctgcg
    25201 attagcagac ggctatgctc tggttgacgt gatcggtgaa gaagaaatgt tgtttagcga
    25261 acactatgcc tgtccttatt gcggatttac tgttggcgaa ctagaaccaa gactgttctc
    25321 attcaatgcg ccttttggag cttgtccaga ctgtgatggt ttaggtgtca aattagaagt
    25381 cgatcaagat ttagtgattc cagatagaac gaagacactt agtcaaggtg ctatcgttcc
    25441 atggaatcca atcagctctc agtattatcc tcaaatgtta gcgcaggctt gtgaaagttt
    25501 cggtatcgat ttagatacac cattcgaaga attaccggaa gagcatcagg agatcatctt
    25561 gaatgggaca gatgatcttt tccatttcca ttatgaaaat gattttggtg gcgttcgcga
    25621 tgtagaaacg actttcgaag gggtattgaa gaatatcgag cgtcgttatc atgatacgaa
    25681 cagtgatttc acgcgtgagc aaatgcgtct ttatatgaca gaattaactt gtcagacatg
    25741 taaaggttat cgattgaatc cccaagctct atctgttcaa atcaatggaa cgaatatcgg
    25801 gcaaacaaat gagttgtcta ttcaaaaagc agtagatttc ttctcaaact taacgttatc
    25861 tgaacaagag aaagtaattg ccaaaccgat tttaaaagaa gtaaatgaca gactttcatt
    25921 cttggaaaat gtgggactag actatctaac tttgagtcgc gcttccggaa cattatctgg
    25981 gggagaagcg cagcgaatca gattggctac acaaattgga tcgaatcttt ctggagtttt
    26041 gtatatttta gatgaaccat cgatcggatt gcatcaacgc gacaacgatc gactgattgg
    26101 ctcattaaag aaaatgcgtg atcttggcaa caccctcgtt gtagtcgaac atgatgaaga
    26161 tacgatgtgg gcagcagatt atttgattga cgtcggacct ggggccggag aacaaggcgg
    26221 acaaatcgtg gctgcaggca ctcctgaaga agtagctaat gatgaaaatt ctttgacagg
    26281 gaaatatctt tcagggaaaa aatcaatccc tgtaccaaaa gaacgccgta aaggtaatgg
    26341 gaaagcaatc aagatcactg gtgcttcaga aaacaatctg aaaaatatta gtgttgaatt
    26401 tccattagga gaatttgtag cagtcacagg tgtgtctggt tctggaaaga gtacattggt
    26461 caatagtatc ttaaagaaat cgttagcgca aaaattaaat aagaattctg ctaagccagg
    26521 taaattcaag acaatttccg gctacgaaag tatcgaaaag atcatcgata tcgatcaaag
    26581 cccaatcggc cggacgccga gaagtaatcc agcgacttat acaagtgtat ttgatgatat
    26641 ccgtgggtta tttgctcaaa cgaacgaggc aaaaatgcgg ggttataaga aagggcgttt
    26701 tagtttcaac gtaaaaggcg gtcgttgtga agcttgtcgc ggggatggaa ttattaagat
    26761 cgaaatgcac tttttgcctg atgtctatgt tccttgtgaa gtatgtcatg gtaaacgata
    26821 taattctgaa acattagaag tgcattacaa aggaaaaagc attgctgata ttttggaaat
    26881 gacagtagag gatgctgtag aattcttcaa gcacattcca aagattcatc gcaaactgca
    26941 aacgattgtt gatgttggct taggttatgt gacgatgggg caaccagcaa cgacattgtc
    27001 cggtggtgag gcacaacgga tgaaacttgc cagtgaattg cacaaaatct ctaatggaaa
    27061 gaatttctat atactagatg aaccaacgac aggacttcat agcgatgaca tcgcccgctt
    27121 gttgcatgta ttacaaagat tagtagatgc tggtaacaca gttttagtga ttgaacacaa
    27181 tctagatgta atcaaaacag cagattatat cattgattta ggaccagaag gtggagaagg
    27241 tggaggaacg atccttgcga ctggaacacc agaagaaatc attaacgtaa aagaaagtta
    27301 tacaggtcac tatttgaaaa aaataatggt ataaagagga tagatagctg agatagttaa
    27361 aaaaacataa aaaaatgaat ttttgcttgt tttattaata tcagtgttct agaatcatta
    27421 catggtagtt ctttctacac tgattggtat agataaaaac ttcctataag ttcaatccgt
    27481 tcaaaaaaga attgagcaat cggaggactt tcctttgatt gcttttttct ttatggtatg
    27541 atattccttg tgtagttgga aaagaaaaac aagagattat gagtaagtga gagataatga
    27601 tgaacagtat tgaaaatgaa gaatttatcc ctatattatt aggaagcgac atgaacgttt
    27661 atggtatggc acgttctttt aatgaagcat acggcaaaat ctgccaagca tatgcttcgg
    27721 atcagttagc ccctacccgc tacagtaaaa ttgtcaatgt agaagttatt ccaggatttg
    27781 ataaagaccc tgtatttatc gagacgatgc ttcgtttggc aaaagaaaga tattctgata
    27841 agagtaaaaa atatcttttg attgcttgtg gtgatggata tgcagaattg atctcccaac
    27901 ataaacaaga gctgtcagaa tattttatct gtccatatat tgattattct ttatttgaaa
    27961 ggctgatcaa taaagtaagc ttttatgaag tttgtgaaga atatgatctt ccgtatccta
    28021 aaacattgat cgtcagagaa gaaatgttag taaatggaca tttggaacag gaattgcctt
    28081 ttgaattccc agttgctttg aaacctgcaa acagtgtgga gtatctttct gtccaatttg
    28141 aaggaagaaa aaaagctttt attttagaga ctagagaaga gttcgattta attttaggcc
    28201 ggatatacga agccggttat aaaagtgaaa tgattgtaca agattttatc ccgggtgatg
    28261 atagtaatat gcgtgtgcta aatgcgtatg tagatgaaga tcatcaagtt cggatgatgt
    28321 gccttggtca tccactatta gaagatccta caccagcatc gattggtaat tacgttgtga
    28381 tcatgccaga ttataacgaa aaaatctatc aaaccattaa ggcatttttg gaaaaaatcg
    28441 aatatacagg ctttgccaat ttcgatatga agtatgatcc tagagatgga gaatataaat
    28501 tatttgaaat caatttgaga caaggtcgta gcagtttctt tgtgacattg aacggcttga
    28561 atctggctcg ttttgtcaca gaagatcgag tgttcaacaa accctttgtt gaaacgacct
    28621 atggaacgaa tcaatcagat aaagcaagat tatggatggg tgtgcccaaa aaaatctttt
    28681 tagaatatgc tcgggaaaat gaagacaaaa aactagctga gcaaatgatc aaagaaaatc
    28741 gttacggtac tactgtattt tatgaaaaag accgatcaat caagcgctgg ttgttgatga
    28801 aatatatgtt ccataactat attccaagat tcaaaaagta ttttcatgtg aaagaaggct
    28861 agttcatgga gaattttttc agtattttag gcggaatggg cacgatggcg acagaaagtt
    28921 ttgttcgctt gatcaaccac cgaacgaaag ctacaaaaga tcaagaatat ttgaattatg
    28981 tcttattcaa tcatgcaaca gttcctgatc gtacagctta tattttagat cgatcagaag
    29041 aaaatccaat gccgtttctg ctggatgata ttgagaaaca aaatttattg cgaccaaact
    29101 tcattgtgtt gacttgtaac accgcacact acttttttga agagttacaa gcggcaacgg
    29161 atattcctat cttgcatatg ccaagagaag cagcaaatga acttgtccgt cagcatacga
    29221 cagggagagt agcgattcta ggaacagaag gaagtatgaa agctggaatc tatgaacgcg
    29281 aagtcaaaaa tcttggtttc gaaacagtga ttcctgatac tgcgcttcaa gaaaaaatca
    29341 attacctgat ctatcatgag atcaaggaat cggattattt gaatcaagag ctctattacg
    29401 aaatcttaga ggaagcggta gagcgcctaa actgtgaaaa agtcatccta ggttgcacag
    29461 aattatcttt gatgcatgaa tttgctgaag ataatcatta cccagtgatc gatgctcaat
    29521 ctattttagc ggatcgaacg atcgaacgtg cattagctga aagaagcgag gcattggata
    29581 cagcatcgga aaagtaaaaa aattggattt ggggcaaata tcctaaaaga tatttggtcc
    29641 aaatcttttt gtaaaagaaa aagaaaactg gtaatgatac gcccgggatg atataatttt
    29701 attatgcaca atgtgagagg ggttcgtaaa tatgacagat aatttgcaat tagtcatcat
    29761 aacaggtatg agtggtgcag ggaaaacagt agctatccaa agttttgaag atatgggcta
    29821 tttttgtatc gataatatgc cgcctcgatt gattccaaaa ttctgggaat tgatcaaaga
    29881 atcaggtaaa gtcacaaaaa tggctttagg agtggatttg cgttctcgtt ccttctttga
    29941 agaaatccaa aacatgctga tcgaaatcga aaatacgaac ttcatcgaca cttctatctt
    30001 atttttagat gcttcagacg aagaactagt ggctcgctac aaagaaacaa gacgagcaca
    30061 tccaatggcg atggacggtt tgatcactga agggatacgt aaagaacggg cgatactaga
    30121 cgacttgaaa gcccaagctt ccgtgatcat tgatacgaca acattgacac cacgacaatt
    30181 acgtgaaaaa atcaatgagt cattcaaatc aaagggagac caaggatttc ggatcgaatt
    30241 tgtatcattt ggttttaaat acgggttgcc gatcgattcg gatattgtga tggatgtgcg
    30301 ttttttgccc aaccctcatt atatcccgga actaagacca ttgaccggaa aagatcagcc
    30361 agtctatgat tatgtgatgt cctttgatga aacgcaatca ttctaccata aatttttgga
    30421 tcttctggaa actgtattgc ctggatacat taaagaagga aaaagcagct tgacagttgc
    30481 aatcggctgt acaggcggtc aacaccgttc tgtggcattg actgaacgtt tggcaaatgc
    30541 tttagggaaa aactataaag tcaatgtgac acatcgggac aaggataaaa ggaaagagac
    30601 ggtgaaccgg tcgtgaaaat gaaaacctac cggataagaa aaccaaagat cgtagtggtc
    30661 ggcggtggca ctggtctgcc agttatcctg aaaagtttac gaaatcaagg agcagatatc
    30721 acagcagtag tgactgttgc agatgatggt ggaagcagcg gtgcaatcag agaatcgatc
    30781 gctatggctc ctcctggtga cttgagaaat gtcttagtgg cgttatcgga tatgccacaa
    30841 ttctatgaag atattttcca ataccgtttc aaaaaggaag atcagttttt agccaatcat
    30901 acgatcggta atctgatcat tgccgcagtt tccgagatgc ggggaagcac ttatgaggcg
    30961 attcaattat tagcaaaaat gatgcatgta gatggacatg tttatccttc ttcagaaact
    31021 cctttgacct tgcatgctgt ttttaaagac ggaacgactg cagtaggaga atctaaaatc
    31081 gcgatcaacc gtaaaaccat tgaccgtgtg tatgtctgca acacaaatga taaaagtgaa
    31141 gccaaagcgg ctcgaaaagt cgtttcagca attatggacg ccgacatggt cgttttggga
    31201 cccggaagtt tattcaccag tatccttcca aatttagtga taccagaaat cggcgaagca
    31261 atgctcaaga caactgctga aaccgtctat atctgtaata tcatgaccca aaaaggggaa
    31321 acggaacatt tcacagatgc cgatcatata cgtgttttac acaagcattt gaatcagcct
    31381 tttatcgata cagtattggt caatacggaa aaagtgcctg aagattatat ggacccagag
    31441 atctatgatg agtatctagt acaagtcgca cacgacttca acggattgag aaatgaagga
    31501 tgtcgagtga tttccaccga ctttttagaa ttgaaagatg gtggtgtctt ccacgatgga
    31561 gacaaagtag tagaagaatt gttccgttta gttttcggtt caaaatatta agcaatttat
    31621 tgttggagaa aggaggagaa taggatgtca tttgctgcag atgtgaagaa agaactaact
    31681 ggtttggaag ttcatcgaga acatgcgaaa gcggaattag ctgctttgct gcgaatgaac
    31741 ggctctttag gtattgtgaa ccagcagttt attttgaacg tccaaacaga aaatgctgca
    31801 attgccagac gtatctattc tcttttgaaa gatcattatc aggtacgaag tgagctactc
    31861 gttcgtaaaa aaatgaaatt aaaaaagaac aatgtctata tcgtccggtt gaagcaaggc
    31921 acaaaagatg tgttgatgga tcttgatatc atggatggta tgatgttcaa tggacacgtt
    31981 tcggacgaga ttatgggaaa ttcgcaaaaa atgcgttctt acttacgtgg tgcttttatg
    32041 gcctcaggtt cagtcaataa tccggaaacg agtcgttatc atttggaaat attttctatt
    32101 tatgaacagc ataaccaaga catttgcgat atgttaaatt attacggtct acatgctcga
    32161 acgcttgaac ggcgcaatgg ctatatttcg tatttaaaag gagcagaaaa aattgctgat
    32221 ttcttaacat tgattggtgc aaccaactca atgctccgat ttgaagatgt tcgaatcgta
    32281 cgggatatga gaaattcggt caatcgtcta gtcaattgtg agacagcaaa tctgaacaag
    32341 acgattgatg cggcttctaa acaaatcgaa aacatcgaat tgatcgaagc aaaggtcggt
    32401 ctacatgccc ttcctgaaaa acttcaggaa atcgcagaac ttcggcttca acatccagag
    32461 gtcagcttga aagaattagg ggaaatgatt ccctcaggtg caatatcaaa atcgggaatt
    32521 aatcaccgaa ttcgcaaaat aaatgaattt gcggaaaaac tgcgtgaaga agcagtttaa
    32581 tccaaagaaa aaactgatac atgaagcagg agatgcgaat gtatcagttt tttttaaaag
    32641 ctatacttgc ttttcttccg tcaaactata attccaactt tactggagta acataatgtt
    32701 gaaaggcttc tattgttttt taatacaatc gtataaaaag cggggagaca actgaatgaa
    32761 gattttagtt ttatacataa acttttgctt aatatagaag tcctgatata gataggatca
    32821 agtatttatc tataactgga gattaattaa aaactggaag gaactgctcg atcaaccttg
    32881 agaactgttt ttcttacttc tggtcaagat tctcgtggtt ggtggataag gatggttgat
    32941 aagttcattg gattagctag tcgaaaacaa ccaggtgtaa ttaatgtaga agttttaaca
    33001 aggggatgga gtgatttatt cagtgataat cataagttca taaatagtaa ttgggatgta
    33061 tggttggtat acgttatacc tgaacttgaa ctatcaagat ttggtttaga atttgagaat
    33121 cgatgtttat aaagggaggg caaaaaatgt gcttttttac aacttttact atcattatga
    33181 ttgcagtact ttttattttt ctagatatag caaagcgaaa tacagcattt ttattatatc
    33241 gggttttact tcgagcaggt ctcataacat ttatatcgat cgttggattt tttctattca
    33301 cagttattgt atttatttgg agaactacag caccaccatt gccagagatt acatatggag
    33361 aatttccgtt tagtcttgaa tatgaaatag atgaggaaag aattttgatt gaagatacgg
    33421 tgattgcaga atttatagga agttttagag ggaatgtgac aactcaacct agacgaagtt
    33481 ggagtataaa acttttaaat aatagtggag agttgaaagc atttcattat gaattcttaa
    33541 taatagaaag tgaagatgta acaatcactt taagtagtgg ctctgctgga tattttatga
    33601 atgatggtgg aagcaagcca cagctcacag tccgtgatcg tattgcaggt tttatgcatt
    33661 tttctcacta tgacttagaa gaagctcgta aaatacttgc agaatatggg atcacattaa
    33721 tcaattggga atatgcgcca ccgataagaa attttttcaa tgattattat tagtcttata
    33781 aaaaacagaa tgtaaaattt atgtgcgcga gtatttagtt ttccattttt tgtttgatag
    33841 atatatagca ttgttgaagc atgggatagt ggtgccaatt ttatcaatga ggttggtcag
    33901 gcagttaaca taattggtga tgctataaat ccatttaatt ggaattggag gaattaggtg
    33961 tggaaacagt gagattatgg atattcatga aaaattttcg ttcggctttg agatatgtta
    34021 ttctggaatc aaaatcaggt tattatctga ttgacacaga tcactatact ttttggggag
    34081 gctacctttt tccgattttt aattggataa tcccccataa ggttatgaaa attaacttgc
    34141 ctgcagaaga aataaataga ttaatactca acaaagattt acaaaggaaa agagagaaag
    34201 aacattctaa tgttgcttgg ataggtccag catttgcagt agtgacttct tcaattgtcg
    34261 gtcctatgct agagagtatt tatagtgatt tttctattgg aatacgttat ttatttgtta
    34321 ctttaagtat agctgttctt ttgtgcataa agggttatgt tagcaagaag aataaagata
    34381 ttttaacact aatcggtgta aacaatttat ctagtactaa aattatactg tttcctgaat
    34441 ctataaaaga aggatcaagg ttgttgataa tttttataat gcttatactg ttttctgttt
    34501 tatttggggt gatgtttata
//
LOCUS       DAFEKH010000029        32302 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.030, whole genome shotgun sequence.
ACCESSION   DAFEKH010000029
VERSION     DAFEKH010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32302
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.030"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(126..1229)
                     /locus_tag="LP386_001548"
     CDS             complement(126..1229)
                     /locus_tag="LP386_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBL1918787.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLRDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            complement(1451..1921)
                     /locus_tag="LP386_001549"
     CDS             complement(1451..1921)
                     /locus_tag="LP386_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HBL1918788.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            2178..3497
                     /locus_tag="LP386_001550"
     CDS             2178..3497
                     /locus_tag="LP386_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HBL1918789.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
     gene            3938..5578
                     /locus_tag="LP386_001551"
     CDS             3938..5578
                     /locus_tag="LP386_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HBL1918790.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAVFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            5732..7054
                     /locus_tag="LP386_001552"
     CDS             5732..7054
                     /locus_tag="LP386_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HBL1918791.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(7116..7547)
                     /locus_tag="LP386_001553"
     CDS             complement(7116..7547)
                     /locus_tag="LP386_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1918792.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(7611..8447)
                     /locus_tag="LP386_001554"
     CDS             complement(7611..8447)
                     /locus_tag="LP386_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBL1918793.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQAIVIVVLLINLYNAFVILQTLEGSGFKQVKITEKSF
                     FK"
     gene            complement(8637..8939)
                     /locus_tag="LP386_001555"
     CDS             complement(8637..8939)
                     /locus_tag="LP386_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HBL1918794.1"
                     /translation="MTEHNHSHEHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEE"
     gene            complement(8965..9396)
                     /gene="ruvX"
                     /locus_tag="LP386_001556"
     CDS             complement(8965..9396)
                     /gene="ruvX"
                     /locus_tag="LP386_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HBL1918795.1"
                     /translation="MRVMGLDVGSKTVGVAVSDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(9393..9659)
                     /locus_tag="LP386_001557"
     CDS             complement(9393..9659)
                     /locus_tag="LP386_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HBL1918796.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(9913..10638)
                     /locus_tag="LP386_001558"
     CDS             complement(9913..10638)
                     /locus_tag="LP386_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HBL1918797.1"
                     /translation="MSKKTTKAIVGIVAAVIAGALGISTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(11004..11074)
                     /locus_tag="LP386_001559"
     tRNA            complement(11004..11074)
                     /locus_tag="LP386_001559"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11040..11042),aa:Gly,seq:ccc)
     gene            11191..11943
                     /locus_tag="LP386_001560"
     CDS             11191..11943
                     /locus_tag="LP386_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBL1918798.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            11959..12438
                     /locus_tag="LP386_001561"
     CDS             11959..12438
                     /locus_tag="LP386_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBL1918799.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(12689..14269)
                     /locus_tag="LP386_001562"
     CDS             complement(12689..14269)
                     /locus_tag="LP386_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HBL1918800.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(14262..15005)
                     /locus_tag="LP386_001563"
     CDS             complement(14262..15005)
                     /locus_tag="LP386_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1918801.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(15181..15957)
                     /locus_tag="LP386_001564"
     CDS             complement(15181..15957)
                     /locus_tag="LP386_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1918802.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(16205..17041)
                     /locus_tag="LP386_001565"
     CDS             complement(16205..17041)
                     /locus_tag="LP386_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HBL1918803.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(17052..17981)
                     /locus_tag="LP386_001566"
     CDS             complement(17052..17981)
                     /locus_tag="LP386_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBL1918804.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            18173..18526
                     /locus_tag="LP386_001567"
     CDS             18173..18526
                     /locus_tag="LP386_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBL1918805.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(18600..19256)
                     /locus_tag="LP386_001568"
     CDS             complement(18600..19256)
                     /locus_tag="LP386_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBL1918806.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            19482..21416
                     /locus_tag="LP386_001569"
     CDS             19482..21416
                     /locus_tag="LP386_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBL1918807.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(21502..22725)
                     /locus_tag="LP386_001570"
     CDS             complement(21502..22725)
                     /locus_tag="LP386_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBL1918808.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(22719..24617)
                     /locus_tag="LP386_001571"
     CDS             complement(22719..24617)
                     /locus_tag="LP386_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HBL1918809.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            complement(24611..25729)
                     /locus_tag="LP386_001572"
     CDS             complement(24611..25729)
                     /locus_tag="LP386_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBL1918810.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(25812..26645)
                     /locus_tag="LP386_001573"
     CDS             complement(25812..26645)
                     /locus_tag="LP386_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL1918811.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVSATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(26638..27555)
                     /locus_tag="LP386_001574"
     CDS             complement(26638..27555)
                     /locus_tag="LP386_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1918812.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(27782..28906)
                     /locus_tag="LP386_001575"
     CDS             complement(27782..28906)
                     /locus_tag="LP386_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBL1918813.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            29089..29997
                     /locus_tag="LP386_001576"
     CDS             29089..29997
                     /locus_tag="LP386_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1918814.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            30138..31751
                     /locus_tag="LP386_001577"
     CDS             30138..31751
                     /locus_tag="LP386_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL1918815.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
BASE COUNT         9979 a         6412 c         5502 g        10409 t
ORIGIN      
        1 agtatgaaaa aatatttcaa ttttattttt tcgtttcaaa ttattctatt agtgacatcc
       61 ttgaactata aaaataggag tacggcatca tctgccgcac tcctattttt ttcgtcattt
      121 gtttcttaaa taaaacgatt ctcacgcaat tttatttttt tgatatcttc tactgtttgt
      181 gttccagcta attgcatgac catttccaat tctgttttaa agaaatcaaa cacttgatgg
      241 actcctgtac ttcctcctaa agacaatcca taaataacgg gtctgccaat agcaacaaga
      301 tctgcacctg atgcgattgc tttgaaaaca tgctgtccgc gtcgtacacc gctgtcaaac
      361 acgattggta cacgtttatc tactgcttct gccacatatt gcaacgaatc aaacgctgct
      421 ggaccaccat ctagttgacg gccaccatga ttagataccc agattccgcc agcaccagat
      481 tctaatgaac gatagacatc ttcttctgac tggacacctt tcacatagac tggcaaatca
      541 gaatgagcag caataaattc tacatctttt ggactaagct tctgtttgga agatttgtac
      601 acagcatcca tcgtttggcc tactcctgat tgataagcct gaacgatcgg cattggcagt
      661 gggaaggtaa acccatttct gcggtctgtt tcacggtttc cgccaactgt tgcatccgct
      721 gtcaatacga ttgcttttgc tccattacgc ttggccactt caagaatatc caaattgatc
      781 ccatcatctt tgctcatata aaattgaaac cattgcggtg ctttctcccc gcctgcttct
      841 cttatctctt ctaatgtaca agaagcgtaa gaacttgctg tatagatcgt cccaaaatct
      901 gctacacctt ttgcagaagc tttctccgcc ttcacatgag ctaagccatg agcagcaact
      961 ggtgccatga tgattggtgc agtcagcgtt tctttgtcaa aatgtgtagt tgtatcgggt
     1021 aattctacat ctcttaatac atgaggaata atcagctgat gattgaatgc ccgttcattt
     1081 tcttgataag taaataagtc gccagcacca ctgctgatgt aaccataacc accagctgga
     1141 atcacttgtg aagcggctat ttctaaatct tccatattga taaaatccac tattccttca
     1201 tttgtacctg cttgatacgt tttttccatt tcaatgcctt ccctctataa aaaattgaat
     1261 gaataatatg atagcgttta cacactttat attactcttc cgtattgata caggcaaata
     1321 atctgtttac atttcagtca ttccagttgt tactactctg aaagaaatgt ttagaacaca
     1381 aatagataaa aaacgatggg attttgacaa aagtcgtgtc aaagtccctt ttacgaaata
     1441 ctgtggatgc ctattgaaat aagtgcgggt tgtttctttg tatttcaatc gtttcttgcc
     1501 attcttcgtt taattttgga ttaccgtttt cttccttgaa cgcataaggt cccaatccaa
     1561 aaagctcagt tagtatttga ttcacgattc catatagctc ggtgtgatcg gacacatgat
     1621 tattgaagat catctcatta tcaccacgtt tgaatctcac attcgggctc tcatgatgaa
     1681 cctctatgca gttttcccct ttttttaact gacggatttc tgaaaacatc tcataaatat
     1741 cttctccaat aaaaccttca gcaagcgcca gactgtccac aagaccgcct actgtcaact
     1801 cagagattat cgctttgttg gcaccaagct ttaatgtata gcttgttgct tctactacgc
     1861 cgcatgcatt gcaaccacct tctgatagtt cgctttttct gatcaattga acttctttca
     1921 ttttctgttc ctcctcttag ttttctactt atgtattttt tatcacctga cgtaagtgta
     1981 ttttatcgtc acgatcacgt gatttattct tcagagattc tacctgaata attcatactt
     2041 ttaattaaaa ccatgtgaaa ctgcctcacg gcagcttaca attacttttt catcttcacc
     2101 cgttaagtga tgaaaaaaga acccctttct gctatggtta aagtgactaa accaaccaaa
     2161 agaaaggagt tcttttcatg actagcttac acaaaaacca agtaaaattc aattcaaata
     2221 tcactatttc tcatacaggt ggtcaattat cgagtgattc gggtctcgtc ctagtgaaag
     2281 agctgatgaa catctttggt ttttctgaac tggctaagca acacattcac attgaagacg
     2341 aacgagcgta ttttactcat gacaacttat ccatacttga gcagttcatt atgcaattaa
     2401 ttgctggtta ctcagctgat tctgcagcta atctcctgag acaagatcct gtgtttaaag
     2461 ctgttttaga taggaaagaa ctcgcttctc aatcttcact ttcccgattt ttagatcgac
     2521 tatctgagga gaatatccat gaacttcaag ctttgaacca agaacttatc gataaagcac
     2581 gcctcatccg taatgatacg gaattaatca ttgatttaga ttcgacccat tcagatacat
     2641 ttggtcacca agaacaaacg aattataata cacactacca aacctatggt taccatccat
     2701 tggtagcttt tgacggattg actggtgact tcttaaaagc tgaactacgt tcaggaaatc
     2761 aatatacatc aaaaggcgta aaggagtttc tcacaccttt attagagcac tataatcact
     2821 ctctaccaaa cactgacatc ttggttcgtg gagacagcgg gttcgctaca cctggtgtgt
     2881 atgattcgtg tgaatcaaaa aagagtcatt atgttattcg actgaagaat aatcgtagac
     2941 taggtcaaat agctgagaaa tcagtacttt atggcgataa tcaaaagtgg gaagaacgag
     3001 aagttcagta cttctcgacc acttatcaag cacaatcctg gtcacaaagt cgtcgcgtgt
     3061 gtatacgctc aacacgtgaa gcgggcgaac tactctttcg acatgaattt atcgtgacga
     3121 atctatcaga aaatgtttct cctgatacca tcttttctat ctatgccaaa cgtggcacaa
     3181 tggagaactt cattaaagaa gcgaaagctg gcttttactt tgacaaaaca gacagtcctc
     3241 gctttttgga gaatcatgtc cgaatgatgc tcagcttgat agcttacaac ttagtcaact
     3301 tcttaagaac gattggcttt gaagaagtcc aaaagggaat gaccattcat tctattcgat
     3361 tgaagtttct gaaagttgct gggaaattag tccaaacggg tagacgagtc tatctcaaat
     3421 tatctagtta tcatgtgtat cagaatgaat tctacagggt ctttgctcgc ctgaggcgag
     3481 ccagtcaatg gatctaatcc aacaatctaa cgattttttt actgggaagt tatccaggga
     3541 gaagtatgct caaaatgcct tacacccaaa atttattcct caatattttt gaacagtgaa
     3601 tgtttgaagt aactttttag tcaaaatcag ttgataggga tattagtgat acatatttca
     3661 ataaaatgtg ccaaagaatt aaagctatga attattcagg attctattta tctatctaac
     3721 atatccttta ttcttctact tttctttctt tagcatataa gagatacgca tagtaatcaa
     3781 gcaaggattg ttgatataaa aagaacaaat accgctattt tgatttcttt tgactctatt
     3841 actcatataa ataaaattta ttatacctgc tctttttgac tatatcctca tctgactcct
     3901 atacttcgtt tgtattaaaa cttaggagga atcattcatg cttacagggc taaacttatt
     3961 aaataatcct tttctaaata aaggaacagc ttttacaaaa gaagaacggg caaaatacgg
     4021 aatcactggt atgcttccaa gtactgtcca aacattggaa caacaatctg tccaagctta
     4081 cggtcaatac ttaagcaaac agaccgattt ggaaaaacgt atcttcttaa tgaatctatt
     4141 caatacgaac cggacattgt tttataaatt gatgggcgaa catttagttg aattcatgcc
     4201 tgtcgtttat gatcctgtcg ttgcggattc aatcgaacaa tacaacgaaa ttttcttgaa
     4261 accacaagat gctgtatttc tttcaatcga cgaaccagaa aatatcaaag caagtttgaa
     4321 aaacgcagca gatggacgcg acattcgttt gatcgttgtg acagatgcag aaggaatctt
     4381 aggtatgggt gactggggtg tgaacggtgt tgacatcgct atcggtaaat tgatggtcta
     4441 cactgccgcg gctggtatca atcctgcaca agtcttgcct gtatcaatcg acgctggtac
     4501 taataacgaa gaattattga ataatccatt atacttaggg aatcgtcatg ctcgtgtaga
     4561 aggcgaaact tactacgaat tcattgatca attcgttcaa tcagctactg aattattccc
     4621 agaattgtta ttacattggg aagattttgg acgaggaaat gctgcaacga tcttagaaaa
     4681 atacgaagat aaaatcacta ctttcaatga tgatatccaa ggcacaggaa tcgttgtact
     4741 agctggtgta ttaggtggat tgaatatatc aggtgagcaa ttgaaagatc aaacgatctt
     4801 gacatttggt gctggtactg ctggtgtagg tatcgcaaac atccttttag atgaaatgat
     4861 ccgtcaaggt gtacctgaag aagaagcacg ccaacatttc tatcaagtag ataaacaggg
     4921 tttattgttt gaagatacaa aaggattgac tcctggtcaa atcccattcg ctcgtaaacg
     4981 ctcagaattc actaatgctg atgaattgac aaacttagaa gcagttgtaa aagcaatcca
     5041 tccaacgatc atgatcggta cttctaccca acctggagca ttcactgaag aaatcgtgaa
     5101 agaaatggcg gctcataccc cacgtccaat catcatgcct ttgtctaatc caacaaaatt
     5161 ggcagaagca aaagcaaaag atttgattga atggacggac ggaaaagctt tagttggaac
     5221 aggtatccct gctgctgatg tggaatataa cggtgtaact taccaaatcg gtcaagcaaa
     5281 taatgcgttg atgtacccag gtttagggct tggtttgatt gcttcaacag ctacacgagt
     5341 aaatgctgaa atcatttctc aagctagtcg agcattaggc ggaatcgttg atgtaacaaa
     5401 accaggagca gctatcttgc ctccagtagc aaaaatcact gaattctctc aaacgattgc
     5461 tgaaactgtc gcaaaatcag ttgttgcaca aaaattgaat cgtgaagaaa tcacggatat
     5521 caaagaagct gttgaatctg ctaaatgggt tcctgaatat aaatctttag aagattaaga
     5581 ttgttatagt aaaagaacat acagaaactt tgtatgacgt ctaaaaagaa aaaagcgact
     5641 gcggcaaaac agcagccagc caactactgc tcttttgccg cttctctttg gcttttttca
     5701 tacgatacag aataagaaag gatctgtaaa aatggcacaa aaaacaacaa ccgcaactgc
     5761 agttgaggaa aagaaaaaag aagggttttg gtcaacaaaa attaccggcg taagtttgcc
     5821 cctttatttg atcatggtcc ttgtcctgat cattgcaatg gctttaggaa aattaccgac
     5881 gaatatgatt ggcccaatcg ctgttttggt cattttcggt aatttatttc attttatcgg
     5941 aacaaaaatc cctatagtca aaagttattt aggtggtggc tccgtttttg cgatctttgc
     6001 ctctgccgcg attgctacat ttgggatctt acctgagtat gtagtaaaat ccacagaaaa
     6061 ctttgtcagc aatatgggct ttttagactt ttatattgct gccttgatta ctggtagcat
     6121 ccttggtatg aaccgtaatc tattgatgaa agcttctgtt cgttttattc ccgttgcact
     6181 tatttcaatg gtcgtctcct tttttgccgt aggactcgta ggtatgctta tcggaaatgg
     6241 ttttgcaaat tccgttttat atatctcatt gcccgcaatg gctggtggtg ttggagccgg
     6301 agctgtacct ttatcaacga tttatgcaaa tgttttaggt acggacgctt cttctatcat
     6361 ttcccgcctg attcctgcga cagcaatgac aaatgtccta gctatcattg gtgcagcgtt
     6421 agttgctcgt gcgggacaat caatgccaaa attcaacggt aatggtaaat taatggaaaa
     6481 aggcgacctt ggcgatggaa aacctagaaa tgtaaaacct tccattccac aattaggtgt
     6541 cggtttgatg gtatcattga ctttcttcat cttaggacaa atctgtaact attttgttcc
     6601 taaagtccat gcttacgcat tcatgatcat tatcgttgtt atctgtaaaa tcgcaaacct
     6661 attaccagaa tattacgaag atgcagctat catgttcaac aacttgattg tcaaaaactt
     6721 gacagcagct gttcttgccg gtatcggtat tgcgttattg aatctaaatg tattggcttc
     6781 tgctttgaca tggcaatttg ttgtcttatg tttgacaagt gttatcgcga tttcagtagt
     6841 ttcaggattt gtcggtcgtt tgtttggttt atatccaatc gaatcaacta ttactgctgg
     6901 cttatgcaac aactcgatgg gtggtacagg aaatgtagct gtcttatctg cagctaatcg
     6961 gatggaactt attgcttttg ctcaaatggg caatcggctt ggtggtgcca tcgttttgat
     7021 catctcaggt ttcttgatgc aattactttc ttagtcaaaa aaaatacctg atcatcaagt
     7081 atcggcttga tgaccaggta ttttttgata aaaatttaca ggattttcaa aaatcttttt
     7141 tgcattttat cggaatgata accgatgcgt tcataaaatc ggtgtgcttc tactctgtat
     7201 tctgcagaat taagtcttat tgctgatatt cctcgtcttt tcgcttcttc tacgccagtc
     7261 atcaaggcct ttccgattcc tcttttttca gcatgtttag acacagcaag tgccataata
     7321 ttgaacatcg gatcgctgaa aatcgattca taggactccg cttgtacata gccagctgct
     7381 tttttagaag taggatcttc atagaccaag aaaaaatttt tttctggctc cttcaacagt
     7441 ttcttcattt gtctcaccgt aacggttaat ggtacatcat atcctaattg ttccgcattg
     7501 atttctcgta gtgcttctgc atctcctaaa cgcatttccc gcaacatcca aatcaccagc
     7561 caatttttat ttttttaaat gaattttttt atcacagtat actccttttt tcacttaaaa
     7621 aaagactttt cagtgatttt gacttgcttg aatccagatc cttctaatgt ttgcaagatg
     7681 acgaaagcat tgtaaagatt gatcaaaaga accacgatga caatcgcttg aaaaataaag
     7741 gtcacttttt ttggagacaa aaccctgcta aatcttgctc cccacaaacc tccaataaca
     7801 gcagcgggga taacataaaa caacatagat aaatcaaagc gcataaagct acttgttaaa
     7861 gcaatcgtta ccaattttgc cagttgagaa aagaaaatcg tagatagaga atatagtgtt
     7921 gcttctttta ttggcaatgc aaacatcagc atcaacaaag aaacattgac tggtccacca
     7981 ccaataccta aaaaactagc taaaaagccc agaacccccc cacatataag gtaccaagtc
     8041 catgacgtca aatgaaattt tggctgatga tgcttggtgt agaagaacgc aaaaaccaag
     8101 gtcaataccg tcaaaaaaat ttggatcagc tgcacatgct tctcgttttc aaataactgt
     8161 aaaaaaactt cgaatacaat gttgccgact actcctccaa caacagctcc actagatacc
     8221 caaccgacaa tctgccaatt cagtgatttc ccgcttgata cttgtcgcac agtcgaaaca
     8281 atggacatcg tgaataccgc aactgttgag taaaaagaaa tccctgcaac agaatgggcg
     8341 ccgataagat caagaatcgg tttgatcaac acgcctccac ccatcccgga aatagcgcca
     8401 actgtgttcg ccagaacgat caccacaaaa taaatcagac caatcatctt gtatttcctt
     8461 tctcttgttt atatctttta gcgattgtta ctcttttctt ttattataca gtaaaagaaa
     8521 caaacgaggc ttcgaaagct tttctacttt ttaaggaaat ttagtgctaa acgaaaaaac
     8581 cgggctctac ttttcagaga gtccagcttt tcttacacct tatcgattct tttgttctat
     8641 tcttcttccg ccatgaatgt attgaatact tcttcgatca tatcccattc tgcgtctgtt
     8701 tcgatttgtt ctaactcgcc ttctgttcca tcttcgtttt cgatgtatgc ataagcttgt
     8761 aattctacat cttcatcttc tgaaacacca gctggatata aaagaacata gttacgtcca
     8821 aattcttctt gtccgtcaac tgttagcaag atttcgtata atgtttcatt tccttggtca
     8881 tccaccaatg tgatgtgttc gtgtccttcg tgttcgtggg aatggttatg ttctgtcata
     8941 agattacctc ttttcttttt attattaaaa taattgctta cctgagccgt ctaaataatt
     9001 ttgtaaaatc atcacagctg ctaatttatc gatgactttt tttcgtttcg ctcttgaagt
     9061 atttgcctgc tctactagca tacgttctgc ctgaacagtg gttagtcgtt catcttgata
     9121 atcaaccggc aaggagaata gttctttgat cttctctcca tatgacatgg aagcttctgc
     9181 ccttggtccg atggaattgt tcatattctt aggtaatcca actacaaaac ggtctacttc
     9241 gtactgcgcc actaattcct tcaaccgatc aaaaccaaac tcttcttctg cctcattgat
     9301 tcgaatgatt tctactcctt gagctgtcca gccaaaggga tcgctcacag caacgcctac
     9361 tgtcttagaa ccgacatcca agcccattac tctcataaat tcactccatg atttgagagg
     9421 tagtctttga caattacttc catgatttca tcgcgttcgt gacggcgaat caaatttcgt
     9481 gcatcacgat aacgaggaat gtaggccggg tctccagaaa gcaagtagcc gacaatctga
     9541 ttgattggat tgtagccttt ttcttccaaa gcccgataaa caatcgctaa tgtttcgctc
     9601 acttcttttt tgcgactatc gtcaaaacca aaacgtacgg tttcatctgt aaaacccatg
     9661 attctacacc tctttcccgc aaggtaattc cagcttacct tctacaccct tattttactc
     9721 gaagaaaggg aaaactacaa acaaatattc caaacttctg aataaattaa gaaacacgat
     9781 ttgtctgatt tttccttttt tctgtggctt tttcaaaagc cctctttcca taaagtatac
     9841 gctatatttc tttgaaagta tgtttttaca caattttttc ataaagttca taaaaaattc
     9901 gaattgctgc tactaatttt tcgttttcgt tgcttgccct gtctcataat tgatggtgta
     9961 gccatcttga acattgtaga taaagacatt gaattcaatt tttttgtctt caatgctttc
    10021 tgcttccaac tgcacacctc ttgctaccag ttcatttccc tcgaaatgag gagtgacacg
    10081 atagcgtaca tgatgatttg tttccttgat atatgccgca atatcatttt cgtgggcaag
    10141 catgtacgga gcattcaacg aacgtgtccc tgtcattaag tttttaatgt tattattttg
    10201 accagtcaac tggaaaccaa tcaaatggct gcggttgtat aaccattgtc cgtcacttaa
    10261 tttcttttgt ttccaacctg tcggatcaat atacaaaggt tctctctttt cagtaggaaa
    10321 caagtctttt cccaacatcg cattggcttg tcctactctg ttcaatttgt ctatatttga
    10381 atagctttcc catgtccctt tggaaagact aagatcctct tttgtaaact ccggctgatt
    10441 cccattgatt tctatttctt gatgttttcc atcatattct ggcacatccg ctacttgaga
    10501 agcttgcggt gtggaatcaa aaatggttgt aatttgttgg aagatatctg aatctttttg
    10561 tgtggtggaa ataccgagtg cccctgcaat cacagcagcg acgatcccca cgatcgcctt
    10621 ggttgttttt ttgctcattt ctttactcct ttactaacag ttccctaaat cttaacatat
    10681 gttcccctat aaataaatac tggaaagaaa tagaaacagt aaaaaaataa aaccagtttt
    10741 tagacggctt aagaatacaa aaaaagagac ggattcatcg tctctactca atcacaaaac
    10801 actatttaca aggtatttat tatcattcaa aaaatttttc ttaatactca aaactaaacg
    10861 gcttctgtac gacctcttgg taaacagtgt tcaaaagctt gcatctgcgg taataagtcc
    10921 aaccaagtca aaaacataag aagctttttt gcttgactat tcttattact tgatgcaggg
    10981 cagctttttc acagcctctt ttaagcgggt gacgggaatc gaacccgcga catcagcttg
    11041 ggaagctggg attttaccac taaactacac ccgcgataca aaaacagtat acgcctcttt
    11101 cactccttcc tcaagttttt ttattcttta cgcttccgat atgttttgta gtaaaataaa
    11161 actaatcaat caattattgg agaagatgct atgacgggaa aagaattaga tctgttgctg
    11221 gacacttgtt tactcgctgg gaaaatcatg atggaaagca atgcggagat gtatcgggta
    11281 gaagatacga tgagtcgaat tgctttagct tctggaaatt tccgtttggt cagctatgtc
    11341 actcaaaccg gtctctttat tggtcttgat cgtacctcga ccatccgaat ggaacaaatt
    11401 accaaccgtt cgattaattt agaaaaagta gtaaaagtaa atgatctttc acgtaaatat
    11461 gttgcttcag agctaacatt agaagaactt tactgcgaac tgcaagcaat cgaccgagac
    11521 cgttctttct ttcctgtctg gttgcaaatc gttagcgcgg cagtgatcag tggaacaatt
    11581 atggtgttat ttggcggaaa gatgaccgat ttacctgtga ctttagtcat tggaggattg
    11641 ggatacgcag cttatctata tagtttgaaa ttttttagaa tcaaattttt atcggaattt
    11701 ttatcttctt tattgattgg catagccgct atctacagcg tacgttttgg cttaggaagc
    11761 aatcaggatc taatcattat cggatgtgtg atgcctttag ttcctggagt tcaaattacg
    11821 aacgctatcc gtgatttgct agctggacat tatgtctcag gagtttctcg cggaacagaa
    11881 gcgatgatga ctgctacgat gatcggtttt gcgattgctt ttattttcca gcttttttat
    11941 taggaaagga acacaagtat ggggacgata tttattcagt tttcttttag ttttttagcg
    12001 actgcggcat ttgccgttat tacaaatgta cctaggcgtt cattgatttg ttgtggtctt
    12061 tctggtgctt ttggctggat gatctactgg atctgtgttc aaataggcgg atctgctgct
    12121 tttggttcat tgcttggttc tttaggagta gcattcatca gcgatctttt ctctaaacgt
    12181 ttgaaaatgc ccgtaacgat tttcaatatt cccgggatgg ttcctctagt ccctggtggt
    12241 ttagcttatc aagcggttcg aaatctcgtt actgaatcct atcgagaagc ggctcattat
    12301 gcggtccaag caattatgat tgctggagca atcgctttag gtcttgtatt atcagaagtc
    12361 tttaaccata acatccgtaa tttcaaagta aagcgtgacg caatcatgat gaaacgaaaa
    12421 aaacggcttt ttaaataaac gaagtgtaac aaagaaaagg ttgtgaaaga gacgttcagc
    12481 cttgagcgat gacaaaatat ctcacaaaca ttgcgacaag taaccgcagg agcaataaga
    12541 agtaattatg agtattaaaa aaagttttgt aaaaatagct tctcacattt ttacataaaa
    12601 ttgacttaat actgagaaac tgacttttga acaccctcta tctgtaaaaa aggggctgcg
    12661 acatgatttt tgtcacggcc cctcttcttt attcaaattt tttccaaaac gttcgttgat
    12721 aataaacgat ccatagagcg gaaagtatta gaactaaacc gatcacagga atattcacta
    12781 accaaaatgg ataaaacaaa gccaacattc cgtataagac gataagaata atactgatga
    12841 tcaatgaacc catcatagtt gcgactaaac ccaaacttcc tgaacctctg ttaaataatt
    12901 ggttaatatt ggtccagttc agcagcagca accgataatc tctagcgaaa taacgtagtg
    12961 acaataagta gcagccgaat aaagaaccaa atagcaagct agggataaaa aacaaaggca
    13021 gctgaaaaga cagtccgctt aataatgcga tcccaccagt taaaaaactc tgcaatatcc
    13081 atccgaatct gaacttttct tttaaatatt ggttcataga gattggcaaa gaacggataa
    13141 acagaaaatt ttcttgatcc aaagaaataa gattgctgat aaaagaagtc tgattaactg
    13201 ttaagaaagc caatgcgatc cctaccagga aaacaacacc gattaactta ttatctaaat
    13261 cagttaattt tatttcgcct cctagggcaa aagcaagaat aaaaatgatt ggagttaaca
    13321 aggaagaaga aagaacttgc ataatcaaat taggttcttt tactaattga gcattgtaac
    13381 taaataaaag ctgatgcaca ttttggttct ttttatgggt tctttttatt ttgaactcac
    13441 tgtttgaatc agtcagttgc tctgtaagct ttggtactat cagctgtttt acagcaagga
    13501 aaaatcccag agccgtgata gctagtattc cccaacccaa taaaccttgt tgagaaagtg
    13561 gctgactggc agcatcatag aatggcaata atatcgaaat cggatgccga tctgttaact
    13621 cattttcaat agtccccgtt tgatgattca tccacatgat tccagcaaat gcgatcagca
    13681 tcgagctgcc aagcaagata ctagaaactg tttttctatg ttttttaaac actgctgttc
    13741 gagccaaacc aaaaacaatc aaactagcca gacaaaaaag aataatcaaa aatagagaaa
    13801 acaaaaggat tgagataatg atagtaagca aaatccctag atcagctcgc catccggtta
    13861 aaataaacat gactagaagc ggaaaaacaa aaggaatgat ggtcaaagca actaccaaaa
    13921 tctttgctga aaaaacctgt tcttgtccaa aaggcagagg caaaaatact tgcaggtcat
    13981 ttccttcaaa aaagatatta taaatgactg atatactttg agttaaacct aacataccaa
    14041 aaagtgccac gtaataagta aagaaacctg gcaatttaac aaagttcata gcaaacatag
    14101 caaatccgta aatcagtaaa aaaatcagcc ctgaaaaaag attttgagac aaaagataga
    14161 tagttaatcg ctttcccttt tttcctttct ctcttgcttt attcgtgagc tgtggattaa
    14221 catataaaag attaactcga attaattcta ataattgtcg cttatacata cggtccatct
    14281 cctgtcgctt gccttccagc cattttcaaa taaatctttt ctagcgtttc atcaggtgag
    14341 ccattcaata attcactaac tgccccctga taaatcaatt cacctttctt caaaatagcc
    14401 agtttatcgc ataactgttg tgcggtatcc aatacatgtg tagaaaaaat gactgttttt
    14461 ccttttgcgg catgagcctt catcatttct ttcaaatcaa atgctgcttg aggatcaagt
    14521 ccttgcaaag gttcatccaa tacccaaata tctggatctg gcagcaacgt gccgatcaaa
    14581 atcgtttttt gacgcattcc atgtgaaaaa cttgcgattg tttcattttg atgactatac
    14641 atatcaaaaa gcgctgtcaa ttctgctaaa cgcttttctt ttttttgtgt gtctaattca
    14701 taggcagctg aaatcaagtc ccaatattct ccagccgtca attgtaaaaa aatatctggg
    14761 gaatcaggca cataaccgat tttttgtttg atactcaatc gattttccgt caatttcatt
    14821 ccatctacta aaatcgttcc cgatgatggt tcaataatac taactaaact tttaatcgta
    14881 gttgattttc cggcaccatt atgtcctaaa aatccaaaaa tttccccttg tcttatcgag
    14941 agagacaagt cttttaatgc ttgttttttc ccgtaacttt tacttacatt gatgaattca
    15001 atcatttctg tactcctttt gtttgttatt actttttatt gtacccttcg ttattggtgg
    15061 agtaaatgtc aaaaagagtg cataacaaaa aaggatagaa acgactaggc tgctacttgg
    15121 gttgttctct tctacaggaa aacactcttc taacaggtaa gatatgagtc tttgttttct
    15181 ttaaaatgat tcattttcta tcttttcttg cataaaattc tttagtttat caatacttct
    15241 ctttcccatc tctagttgtt ctccatttgc aaatgttact atttcgttta ctctgctaat
    15301 agatgtaatg ttttcagtat taatgatata agcttttaaa tctttacata aatactcata
    15361 ttcgagtgat tttttatatt ttttaattgt gccgtttacg agaatctctt catctttcaa
    15421 tactaggcct attttatttt tataacctgg catgctcatt agataaagga tttcatcgta
    15481 atggatatag tgatcgctat taccataacg gacagttgtc cacctttttt tcgtagcatg
    15541 ttgaacagga tagttttctt tttctttcaa taagtaactt tggatgcttt ttttattttt
    15601 ttcataagtg aattctttta tcaaataacc actaggcgta atctttcgat taataacagt
    15661 tattgcttta ttcggatgag acgttagata aacaatttta cacttttcat tcttttctct
    15721 aagcatttcg cctagttcga taccgctata ataggcgttc aaatcgatgt ctaggaaaaa
    15781 aatatctgag gaatagattt cattattttt aatgaattca acaaattgta taacgttcaa
    15841 tccctgaacg atctcaaatt tccaaggact taataaaatt ctggattctt ccaaaatttc
    15901 tactagcatt ttttcaaaaa ccaaactatc atccaaaata aatatacgcg ttaccataaa
    15961 aagtacctcc actcgatatt ttactatcaa aatcatttca tacaactttt caacatacat
    16021 gttaggaata aattgtaatt ctcttcacaa tcttttccaa cacctttgaa accgatatca
    16081 aatactttca ggatgctgct tctaaaataa atatcaaaca aatgaataca tcatgcaaaa
    16141 aaagccagac aaccgacgtc cttgcgtgtc agctgtctga gctatgttta tttattttgt
    16201 tcttttaaaa agaacgatac acatactgat ttttcggagc agagactttc tcagcgtttg
    16261 taacaactac agatgggatt tcacgcttga atggttgata atagtctgat tggatggttc
    16321 cttctatttt ataccattca tcatttttaa ccgttactcc ttccggcata tgcgtcaaca
    16381 aaccaaagac tcctgaatct gccacacaat ggataatgcc gaatcggaac aagaagatat
    16441 ctgtattgct atcgttcggt gtttggtaaa caaatccttc atagctgatt tttttgccaa
    16501 tgaattcgct agggtaatta taaattagct ccataacttc taaatagttt tcatctgtga
    16561 tcttgatagt ttgcttatcc ccatactttt ctttcaactc attcatttgg tctaagtagt
    16621 ctgatttgtt gaaataaata ctggtatccg gctttaagta ttgtgtctgc atctccggat
    16681 cccctactga ttctttactt actgggaaat taaatccttt ggcttctacg atcgtagtgt
    16741 cgagactaac tgttggaaac aacgtcccca cgattactgg caaagctagc agtacataag
    16801 cgattccacg ttgataaggt tttgacaacc catggtcatg atcgtgctcg tgtgcctttt
    16861 cttctgcttt tccgtttttg acccacaaat acagctgaac taaagccaaa agagcagata
    16921 aaatcattga aagaatagct aagtagcgat aatggacatt gatatattga tcgagtttgc
    16981 cagaaacttg caagtacatc atcaattcga aatacccaga taaaatcaaa aaccgcagca
    17041 tattttccct cctaaataaa taatgtgaat ccaataacgc taagggcaat cagtccgatc
    17101 agcgataaaa taaagcgtcc tgtaaaatat cgtttcatca tcagtagatt tttgatatcg
    17161 accattgggc caaagaccaa aaaggcagct acaggtgctg tgccgaacag acttaacaaa
    17221 gaagatccta taaacgcatc tgcttctgag caaagagaca tcgtaaaggc caataacagc
    17281 atgatgataa tggctaaaat ctttgttgag ccgagcgtta gcataattct agttggtaaa
    17341 taagtctgca tcgcagctgc gattaatccg ccaatgatca aataacgacc tgtatcaaaa
    17401 aattcgtcga ttgaatgtgt caacacatgc ccagtttgat ggatcagctg attttttggt
    17461 tcattcttct cactttgttc ttcttcatgg acatgatgat ggtgattttc tgctacttta
    17521 gacgtgattt tttctttcaa tacagcgtct ttttgaaaat aggcaagcca gacaccaatc
    17581 acaagggcaa caaaaaagct gcctatcacc cgccagcttg ccatctgcca agaattgcca
    17641 aatgcgataa aagtggaaaa aatcacgatt ggattgatga tcggagcagt cagcataaaa
    17701 gcaaacgctg tgtgaactgg tacgcctttt ttaacaaatt gatgaacgat cggtacgatg
    17761 ccgcattcac atgaaggaaa gaaaaatcct aagatcgaac cagtaaaaat agagaagata
    17821 cgattttcag gaagccatct cttcacacgt tctggggtca aaaatacttg taaggcgcct
    17881 gagataagac agcctaataa tacgaaaggt aatgcttcaa taacgatcga taagaaaatc
    17941 gtactcatct gcaaaaccga atttggaata aaagaaaaca tgagtttcct cctttttatt
    18001 tctagttcat tcgctttgca aatatacgct tttattcaaa aaaaacaagt tgctctgtaa
    18061 atttttacac aactcttatt ttttaccaaa gcacttcaat tgactttttc tgttattccc
    18121 attaaattaa ggtctcatac atatcacttc tatcataaaa gggagaataa aaatgaaaca
    18181 aaccactaac ttgactgaag ttcaagacat actgcaacag tcatccgttg ccgtcattta
    18241 tctttcgatg cctaattgca gtgtttgtca cgctgttcgt ccacgactag aggaacttct
    18301 cacacattat gatattccgg cacttcattt ggatgcattt gaaacaccag aagtagctag
    18361 taaatttgaa gtgctgactg cgccagttgt cctgattttt catcaaggaa aagaagtctt
    18421 tcggcaagca cggttcatcg actttaaaaa aatccgttat ctactagatg aactgacagc
    18481 agaagatgat tccctttctt atgaagaaat cttccgaaca aaataatcgt tgtccaaaca
    18541 gaaaaaagcg attgaacaag tgaaagtttt gccttcattt gttcaatcgc tttttatttt
    18601 tattctgctg tattttcgga atgcgcattt gcgtcagaat gcaagaaata gatcaaggtt
    18661 tgcaattcat tcgtcaaatc aacattttgg atcaatacat ctgacggagc attcaatcga
    18721 gcagcggtaa agttcaagat tcctttgatt cctgcttccg ttaactgatt gactacttct
    18781 tgtgctcttt cagcgggtat cgttaaaatt gctacttcga tttgttggat cttgatttgt
    18841 tctgacatat cttccattgg ataaacgggg ataccgtcta cgatgcgccc aacgatttcc
    18901 tcattcacat caaaagcaca actgatacgt atgctattac tttgatggaa tttgtatttt
    18961 agtaaagcac ttcccaagtt ccctacaccg atcagcgcaa catttgtcaa ttgatcgtcg
    19021 tttaatgtct ttgcaaaaaa gtgcataaga tcttctacat cataaccata cccacgtttt
    19081 cctaattcgc caaaataaga aaaatctcga cggatcgttg cactatctac ttgaacggct
    19141 tcacttaatt cagttgaaga cacttttttc tttccagcat tatttaaaat ccttaaatag
    19201 cgataataca aaggcagtct tttagctgtc gcctttggaa taatatgatc tttcacgaaa
    19261 tgacctccac gtattgtcta attacatctt tgatttctcc atcatagcag tatttatagg
    19321 aaaaaatcaa ttccattgct cagatattgt gaaattttat tctttattca tttatttatc
    19381 atttctgcaa atctcgcagt ataatggaat ttatggtaga ctactaattg aaaaatagtt
    19441 ttttatttga ggagaattca caaagtagaa aagaggattc catgatatta ttacaagcca
    19501 atcagattgc tcgccatttt ggtgcagaag tcttatttga aaacatacat ttagaaatca
    19561 gtacaggcgc tcgtgtcgct ttagttggca gaaatggcgc tggaaaatcg actttattaa
    19621 agatcattgc tggaattgaa gcacctgatg aaggaaagat cgctaaaaat aaaacagcga
    19681 ctctcggata cctcgctcag gacacaggac ttgattccaa tgaaacagtt tggaacgaga
    19741 tgctgaaagc ttttgaacaa gttagacaaa tggaagagcg gatgcgcgag ctagagattt
    19801 tcattagcga aggtacgcca gacacacctg cttatagttc ttatttaaaa gaatacgacc
    19861 ggctgcaaca cgatttttca gatcgaaacg gctatggtta tgaaaatgaa attcgttccg
    19921 tattgcatgg gtttaaattc gattcttcat tttatgatca gaaaatcgat actttatcag
    19981 gcggacagcg cacacgttta gctttagctc gcatgctttt gcaacaccct gacattttga
    20041 ttctagacga accaacgaac catttagata tcgagacact ttcctggctt gagaattatc
    20101 tgcaaagcta tactggtgca ttattgattg tttcccatga ccgttatttt ttagataaag
    20161 tagtcaatga agtctatgaa ttaagcagaa gaaaaatgcg ccattacaaa ggtaactatt
    20221 cgaaatatct agatttgaaa gcagaacagt tagcaagtga atggaaggct tatgaaaagc
    20281 agcaaacaga aatccataaa ttagaagact tcgttgctcg gaaccttgtt cgcgcctcta
    20341 ccacaaaacg agcgcaaagc cgcagaaaga cattagaaaa aatggaccgg ctggatcgtc
    20401 ctcaagggga tgaaaaacaa gcaaactttc tattcagtat agaaaagcct tctggaaatg
    20461 tagtcttgca aatcgaagat gccgctatcg gatatgataa tgtcacctta tctgaaccaa
    20521 tcaatctaga tatccgtcgt caagaagcga ttgctctagt aggtccgaat ggtatcggga
    20581 aatcgacgtt gctgaaatca atcattcacc agatcccttt tatccgtgga aaagaaacgc
    20641 tagggacaaa tgtcaccatc ggctattacg atcaaggtca agctgatctg catacaaaca
    20701 agacgatcct agcagaattg tgggatgagc atcctaccac tccagaaaaa gagatccgaa
    20761 gtgctttagg tgctttctta ttttctggcg aagatgtaga aaaaccaatc cctctgctaa
    20821 gtggcggtga aaaagcacgg gttgctttag ccaagttagc gatgaacaaa gaaaattttt
    20881 tgattttgga tgaaccaaca aaccatttag atattgacaa caaagaagta ttagaaaatg
    20941 cattgatcga ttatgacggc acactgcttt ttgtttccca tgaccgatat ttcatcaatc
    21001 ggatcgcgac aaaagtcgtc gaactctctg aaaatggcag caaagtctat ctaggagact
    21061 atgattatta tttagagaaa aagcaggaag aagaagaaat cgccgaattg ttggcacaag
    21121 atgagccaga atctgctcct gctcccacga acaaatctga ttattaccaa agcaaagaac
    21181 agcaaaagct tatccgtagc cttcaacgaa aaattactca ggttgaagaa gaaatggcgc
    21241 ggatcgatga atggatcgat cagttggaac aagaaatggt cgcgccagaa aacctggaag
    21301 atcacgtaaa actcaatgag ctgaaccaag atttagaagc tgctagacaa gatcaagaaa
    21361 caaaattgac ggaatgggaa gaactaagct tggaattaga agaatatgaa aattaacgaa
    21421 aaaaccaaaa cagaaaccat tcatgctgtt ttggtttttc tttttttatt ttatcaaaca
    21481 aaaattccat atttaccttt ttcaccaata agaagaccaa ttactagtca ttctcactaa
    21541 agcttctaaa taatagtaat caccccaaat acaaggtgta tttaccccat tatttttggg
    21601 cttattataa acagactgtg ttaaaaagcc atcttcttct tccgttgtag catatctttc
    21661 tttcaattgt cgcataattt tccaaacagc agactggtat aagttctttt ctgttttgtc
    21721 taatagacct gattctatta attctaataa tccacaaacc atgatcacca tactagatgt
    21781 atctttttct tctctgctag aatcatcaaa gatcaaatcc caataacaaa tggtatcttc
    21841 tggcaaccga ttcataaaat aattggctaa tattttgctt aaatcaaaat atttttgttc
    21901 tttcaaataa cgataactta atgcaaaacc gtaaatcccc catgcttggc ctctagccca
    21961 acaggaatta tcactataac cttgatgcgt acttccatat cttggttttc catctttgac
    22021 atccatataa aatgtatgat aagttgaacc atcttctctt actaaataat ctgctgcatt
    22081 ttgaatatga gcctgagcag cttttttata tttttgattt ccagtttctt cactcgccca
    22141 atacaataat ggaagattca tgcaacaatc catgatcatt ctaccttgtt gtgaaggatc
    22201 actaggatct ccccaagctt gtataactcc tgccttctcc caaaaacgct gaagtaatgt
    22261 ttctgcagca tcaattgaag cttccttcat ttttcgattt cccgttattt tataatctgc
    22321 tacggttgat aaagaataca aaaaaccaag atcgtgatga ttagtgataa tttgacagtc
    22381 aatcctgtgg ataaaatcta tatctgcttt ttcagctgtt tgttgaaata aaggatcacc
    22441 cgtcttctca aataacaacc aattaattcc tgtccaaaat ccttctgtcc aaccaatatt
    22501 gtctcttaat ggataacgtc cttttatagg acactcgctt gggaattgat actgactgtt
    22561 actgatacgt ttgattaacc tctccgtgtg tctgcgacaa cgctcgatct cattattcca
    22621 ttctttttcc attaattctt tataacattc atttatccat ttttctggat gtattatctc
    22681 ttcaaacatc actttatcaa gcatttcccc accagccttt agcataattt tagtcttttt
    22741 ttattgtttt tattttggat agttagcccg gttgtcccat caaaatcaat tttgggacga
    22801 ttgttccata cttctaaact ataatcccga tcttgatgag caaccactcc tgttccgagc
    22861 caatgggttc cttttccaaa tgtaccctct aatccaggaa taaaagtgtt ttcccatgtc
    22921 atcaagtttg tattgggcaa acccataata gctgtggatt ttcgtttaat agtatcgtca
    22981 cttaaacaga taatacctga aaagccagct tcactcaccc tatagttttc cttgtcttct
    23041 tctatgatta ttccttcttt ctcaggagaa cattcaatag caaaccctgt ctcatataga
    23101 acatattctg tatctaattc tactttgtgt acgcgaatct gccagccttc aaaaggaata
    23161 agccaagttc tgatttttgc ctgtaaagta ggttcccatg tagaggcaag tacctctttc
    23221 ttacatacaa tgtctcgtac attatttcga acgatgaact gtccataggt tttgatgctc
    23281 tcattcttaa aactggtcgt gatatatgtg tccgctcgct gaatccctag cattgaatcc
    23341 attgccattt ctgctttcaa ttgattcgct cgcggtatcg aaaaaccaaa ttgactagaa
    23401 taagcaaatt ttaaatattt ttcattggtc aatgtatgga aatttggccc taattgtccc
    23461 gcattcaaaa aaaatgtatg tccattatca tgttgtatga gcaaattggc ttctgaaaga
    23521 agtttagttc cttcacgaat aggcataggc atttctttag ccgtccaata ctcatggtct
    23581 tcaggtagcg ccaacaataa aaaaatctta ttcagccata atggagataa cgtactatta
    23641 tagggttcag tcaatgtcaa ttgagggtag gtataaccaa tattcaggat acctttttca
    23701 tcaaatattt ctttttgcat ccaccatctt atattccgat tgactaaccc cttgatttca
    23761 cctaatttaa aaggcaaaag atcggcccac aacatagctg accaaaagct tgaaactgca
    23821 aaacgataaa tcatgcttcg accaaaaggc acatttgcac catcttccgc aaaaaaatga
    23881 atatagtctc tagaaaaatc aatagctcgg ttcttatata tctggctaat gggcttttct
    23941 ggttctagta cgctataaat caaaccataa taatgaaatg caaaaggatt ataataatct
    24001 tggcgacctc ttgaactgtc tcgataccag ccattttgaa gataacaatt ttctatatta
    24061 tcaaatgctt ctttcagtgc tgattcttta actggataac caaatttttg gataattgtt
    24121 ccgacaatta tcttaaaaaa ttgccaatta ccatctgcac attcatattc aaaaatttgc
    24181 gagaaccaat gaataatctg gcttttttct cctgtatcta attttttcca taataattgt
    24241 tcatgatgat ataacgctaa taacattgcg ggcatttcta ccatacgctg gtctctttca
    24301 tgtatttctc cccaataatc gggatgggaa ggatctgttc cagcttttat tcctgataga
    24361 attaatttca accatcgttc atctaattgg tcaattgcgg gccccgctcc ccataaaacc
    24421 cgagagaatc cttccattcc tgcaatttta tttccatatc ctaccccttg atgtatataa
    24481 tcaatttgtg cgccacttgc tcgataaaac ggctggagtg gttgatttat ctttttaaat
    24541 aagtcaaagt aatcctgtct ggtccttaat agtggtactg gatgtttcat tgtattttct
    24601 cctcttttta ctaccaaata gctaattccg actgttctaa tcgaagtaag ccttcaataa
    24661 aaaaataatc agaatagatc agtggcacat tataagtcag ttctctatgg tatgcttctg
    24721 ctccgcctcc aatgatccca tcttcatcca tattccaatt tgcatagtgc ttttctgtct
    24781 tttggagtat attgatagca gcttcatgat acatttttga tcgtacagag gaaacatatc
    24841 ctgctaattc cagaagaccg catgcagcgc atactccagc actggtatca atattcgaat
    24901 cttttacagc aaaatcaatg agaggaatat aaccagtttt ttcgattttc tgaataaaat
    24961 ttactgctat cttttctgct atagctagat agtacggatt ttttgtgtaa cgataactta
    25021 acgcgaatcc atataaagcc catgcatttc ctctgctcca acaagaattc tcattgtatc
    25081 cttgcccgcc aagtaaccga atatatttcc ctgattctgc atcaaattct gcgatatgcc
    25141 cggttgatcc atctttcctc actagatact tagctgttgt atctgcatgc tgccgagcaa
    25201 ttttagagaa cctcggatca ccagtttccc tcgaagccca atacagtaat ggtaaattca
    25261 tcatactatc aataatcatc caaccaggtt tatggtcatt ccatgctact aaatagttcc
    25321 ctgaaatatt atagcgtcca gcaagtaccg tagctgcatg taaccctagt tgtcgactat
    25381 gtttgttttg agactgttga taatgtgcaa tagccgatgg taagaataaa aaacctacat
    25441 catgatgaac gtctgaaaaa tggtacaggg cagattctaa taattgttct tgttgtattg
    25501 ctgcctcttt gaacttttct cgttttgtct tgtgaaagag ctgccataaa ataccactcc
    25561 aaaaaccatt ggtccaccag tcgattcctc tgtcctttat tacgtctgta tattttccgt
    25621 tgtaagaaat atatggaatt ttattcccca ttctgtctaa ttccgcatct atcttttcag
    25681 aagctacatt caaaattttt cttgaccatt ccttcgtctg ttcattcatg gatatcccgc
    25741 cattctttta atttttatga atgtggagtt gctcctagaa cgaactagat ggttaacatt
    25801 cgttattttt tttacttatt tgcagctcca atgtcattct ccttaaattt agactgcgcc
    25861 cacacataaa tcaagaccat tgggatcact gaagttgcta aaattagcat aattgcgcca
    25921 taattaattg gctcacctgt actagaaacc gtcatatttt tgataattaa gggaaccgta
    25981 tatttatctt tatctgaaag catgactaat ggaaatagat attgattcca acttcccata
    26041 aagataagta aaccactagt aataatcgta ggtgataaaa tcggtacagc gattttcgta
    26101 aaaatcaccc actcattggc accatcgatt ctggcagcct ccatcagtgc tgtaggaaat
    26161 tgactgctat attgtcgcat cataaacact gaagttgtac tggcaatcga agggatgatc
    26221 acacctgcat aagtattcga taatcctaaa cgactcataa tgtaaaataa aggaatcaat
    26281 gtggtaaaaa aaggcaccat cctagatagc ataactgtat tgaacaacag tttattcccc
    26341 ataaaacgat actttgctaa tgcataaccc gccattgtag aactggctgt agctgaaact
    26401 gtactgatta cagcaataac aatcgaattc caaataatca agggataatt atatctcgcc
    26461 atgatggctt gccagttttt taatagcata tccccaaact tgaaattgat tccgccactt
    26521 aaaatttctt gattactttg cgttgaagct acaatcatat ataaatatgg catcaaaaat
    26581 attaaggcac caaacacaat aatgacgtac gtaaaaattc tgctttgtat cttttgttta
    26641 gtcattttta tcacctccga atttaaattg aatagccgat aatataacag atacaaacac
    26701 catcgtccag gcaatagcag aggcttttcc aaaatcaacc atttcaaaac ttgttttata
    26761 taaattgact cctacgacca aagctgaatt ttctggtcca ttggaagtcc caaagaatat
    26821 atttgggata ttgaaattac ccaagccatt gatagtggct aaaactgtgg ccattaaaat
    26881 gattggcttt agcatgggga tcgttaataa aaagaattgc cgaaatttcg atgctccatc
    26941 tatttcagca ctttcgtata tctctttaga aatcccttga agaccagcta aaaataaaat
    27001 agtgttatat cctacactaa gccaaatcat cgtgatgatc attgatattc gtatccaaaa
    27061 aggatttgtt aaccactgta caccgttaat tcctagcgca ttcaaaaatc cattgaataa
    27121 cccagtcgga ttgaaaaaag tcatgaatac ggaagctaca gccaccgttg atgtaatggt
    27181 tggaatataa tagacagttc taaaaaatcc ttttcctttt aactgtgctg aattcaataa
    27241 aacagcaaag taaatagcta atagcatcgt tattggaatt gatcctgcca tgataatcaa
    27301 aacattcgtg taagatttaa taaacaatgg atctcggaag atagctagat aattgtcaaa
    27361 tccaacaaat tcaaatgagt agccaatttt cataaaacta aaagcaaacg agataatgat
    27421 gggaatcaaa atcgtcacaa taaagaaaat aacaaaaggt gtgaccaatc cataagcact
    27481 ttttttatga gacgtatctg ttgctttttt cttgctgttc tttattgtct tgcttggtaa
    27541 cgaagattgc atcatcgtta agtcctccta atatttttta atcaccagtt aattttacgc
    27601 cgtacttatg agcaaaattt tctgcttctt ttagatatga attttcaaaa tcacctgttt
    27661 gccaatagtt atatgcagcg gtagtcaaat aagacgtagc atctgaataa gtggctggta
    27721 aaacagtatt tgatgtattt tcattgattt tattcaatag ttcatagtat ttttgtcctc
    27781 cttagtagtc aaactttttc tcagctgctt ctgtttgata ggccaatgag ttagatgtag
    27841 ccacgcccag ctccagtgcg ttggctaagc attcttcatc tgtcagcata aatgtaagaa
    27901 attgttgtgc cacttgtgga tttttggcat ctttagggac ataaaaactt gatcctcctg
    27961 atactgcacc ttttcctgga ttttcttttg aaaaaggaat cagtggagcc atgcgccatt
    28021 tgtcagatgc atcaggaaaa ttcaaagaca tattcgtagc ataccagccg ccagcaacaa
    28081 acattgcaga ttcttgaaat gctttctcag catcttgtgc accgtagaaa tgtacaatat
    28141 ctgagtcgat catttctttg attaactttg cagcatgttt cgcttcttta gtattcagac
    28201 ggatatttcc ttcttcatca agcaaagatt gattctgctg ggctagcatg ttgataaaca
    28261 attcttggtc cccagattct ggcaaggcaa ttccaaaact accagttttt tcttttaatg
    28321 cttttgccac ctggatatat tcttcccaag aactgatttc ttcaaaatct acacctattt
    28381 cagcaaattt ttttggttga taataacaaa gtgctggggt aaaatcacta gcccaaggaa
    28441 taatcgtttc attactcgtt tgttgacgca aaatattcaa tttttgatca taaaactgat
    28501 cgccatattt gtcataaaat ccatattcat cagcactata aaaagcatct tgaaattttt
    28561 ccagcacacc tgctgctgaa gtgtctgcca tggagataat atccggcata tcttcgtgtg
    28621 ttaccaattt tggggtgatc atttgtactg ttgctgttcc cgaagctaca ttcacaattt
    28681 ttaagtcaat atttgctcca gttttgcggt tatagatttt tgcagcattt tcaacatagt
    28741 ttgtcagttt gccgtttgcg acatatactt ctaatgtagt ggcttttttt atcattggat
    28801 ctgcgatgtt tgctgttact tcttcgttag tttttccaca tgcacttaag ctgaataata
    28861 gggtaatgtt tagcaaagct atcaccaatt tgtatctttt tttcatgtct atcccttctt
    28921 tcttttcaag ttcttatata aaacgctttc acttatgtat attaacggaa ttagtaacac
    28981 aaatatttat ataaaaaaat attttacttg tcgttttggc ttttcatttt tgttataata
    29041 gtcattaatt ataaatagaa agctttttat ataaaaagag aaaggaaagt ggttcttttg
    29101 ttaacaaaca accaatcctc caatcttgtc aaaaaaacac taacctattc catagatacc
    29161 catcttcatt tatctgctgc tccctatttt cgactactaa taaatgaaag cgctaattta
    29221 tatgctgaat ttgcacataa atctatagaa ctagataatc cttccctttt attcattgat
    29281 aaacagcaag aagtccaaat cttttctact caaaaggaaa cacaaacttt tatcattatc
    29341 cagttttatt ttgatgagca attattagca catattacgg gacaatcttt ttctatagat
    29401 caagaaataa catctatcat tacttttctg aaaaatgaac agttcaaaat tgattatcta
    29461 aaacatagta agccagctat ttcctatgat caggaaatca attctttttt catactatgc
    29521 caacagatga gcattcattt gctttcctta ttagttactt attgtctgca aaaaattcaa
    29581 ttgtcttcct taccaaggca ttatcaacag gaacttgctt tattgacaat accttcaaat
    29641 gagaaagtca ttcctaaaaa aaagcatatt ctttattcag atgaattagt tgatccaatc
    29701 atacgatatt tagaagaaca tctttcagaa aattttttgc ttgaacaatt agcccaaatt
    29761 ttttttatca gtccagccag cttaaaaaaa cattttagaa aagtgaatgg aaaaagtgtt
    29821 attagctatt ttaaagaact aaaaatggaa aaagcaaaac gtctcgtgct agaaaatgaa
    29881 ttaacctata cagaaattgc agatatatta ggatttcatt cgatccatca tttttcttca
    29941 gcttttaaaa aatatacagg gttatcccct tcaaagtatt atctatcctt aaaatagaaa
    30001 aaaattttta ggttttatcc acaaattatt tctctatatt ttctgtctat tcaaaataaa
    30061 caataatttt ccggcacaat tatttgctgt tttttaccat aacatagtac gatcaacgta
    30121 gaaaaggaga tgtttttatg aaagttgttg tcattggcgg tgtagctggc ggtccttcat
    30181 ttgccactcg tttccgtcga ttgaatgaag cgcacgaaat cattatctat gaacgcggag
    30241 aaaatatttc ttatgcaagt tgtgctttgc cttattattt aggaggtgtg atcactgacc
    30301 gtgactcgct gatcgaacgt acaccagaaa tattgaaaac aaaaaacaac atcgatgtct
    30361 ttactaaaca cgaagtaaca gcaatcgatc cttctactaa gcgattaaca gttaaagacc
    30421 tatccacaaa tgaagaaata aaaacagatt acgataagtt gatcatctct tctggtgcta
    30481 gaccagatta tccggatatt cccggagttt ttgaagcaga aaacggcttt gtcctccgta
    30541 gtgtgacgga tgcggatcga atcaaatcgt tccttgaaga aaaaaatcca caacatgtcg
    30601 tcattcttgg tgcaggtgtt atgggtctgg aattagctga gaatttcaag catcgcggct
    30661 tagacgtgac tttaatcgat caattgccac aagtcgcttt cccttatgat ccagaaattg
    30721 ctaatttagt ttatgacaaa ttgctgaaag aaggattagc cgttcattta gaaacaagag
    30781 ttactgagat ccgtgataaa ggtcgagaaa tagtattatc agatggctcc gtcctttctg
    30841 ctgatatgct aatttttgct gttggtgttt ctccgaagaa tgaagtggtg aaagcaaccg
    30901 gcatacaatt atcagataca ggtcagatca ttgttgatga ccagttacaa accaatctgc
    30961 cggacatcta tgcgattggc gatattatcg aaacgactag tgtagtgact ggtcagccga
    31021 tccaaagtat gctttccagt gcggccaatc gtcaaggaca tatgctggca gatattttaa
    31081 atggtacgcc tatgcgctat cgcggatata ttggtgcagg tgtcgcaaaa atctttgatc
    31141 atacagcaag ttatgcggga atgacagaac atgaattaaa agcatcaggc ataacaaatt
    31201 ataaaactgt ttttatcact ccctttgacc atgcctattt ctatccagaa gctacaagat
    31261 taaatctaaa gctgattttt gatgcagata gcggtcgtat tttaggtgga caagcatttg
    31321 gagaaaaagg tgtcgataaa cggatgggag aactttctgt agcaatcacc ggaaacttga
    31381 cagtctttga tttgcctgat ttggagttgc cttactctcc accgtattct actacccgtg
    31441 acccgttgaa tatagctggt tatgtcgcaa tcaatcaaat gacgaatatc gtagaaacga
    31501 tcaaagcaag tgatataccc gaaaacgatt tgaaagaagc gttcttttta gatatacgtg
    31561 aacctaataa agcaccttct ggcagtatct cggcaacaaa aaatattcca atgaatgagt
    31621 tacgagatcg aatcaatgaa atcccaaaag ataaaaaagt ttacattact ttcagaagag
    31681 gattgaatac ttatacttct gcccgaatct tggcaggttt gggtatcaaa gcgattttga
    31741 ttgaagaata aaaaaacgac cgcggtgggt agccgcggtc taggagttat ttttacttga
    31801 ggagtaaaaa tgaaaaagta tatagggttg ttggttggta tgtatataga atagaagata
    31861 aatgtgaaga aattgtgcat tatttcttca catttattag gttatagttt aagaaagttt
    31921 aaacattgcg caatttaatt attttagctg tttcttttca taaaaaaaca tgttgtgact
    31981 ctgagacaaa tcatagtcca tagtgatgtc tctagagtaa ctacgcctaa tattacgagg
    32041 catcatatta atctatcagc actagtacct aaactagcat ccctttcgaa tattttttct
    32101 tatataataa agtttgcttt cactcctcta atctcaccaa atcgactggc ttgcgttgtg
    32161 tgatactagg aactgattgg tttagaacga cttttctatt gtaatcatat ttttcgccat
    32221 cctcgttgtc ttctaatcct tcaatgaatg atccctaatg tgtgtattaa ataatttaat
    32281 ttttttgttc ctatttattt aa
//
LOCUS       DAFEKH010000030        32207 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.031, whole genome shotgun sequence.
ACCESSION   DAFEKH010000030
VERSION     DAFEKH010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32207
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.031"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            232..663
                     /locus_tag="LP386_001578"
     CDS             232..663
                     /locus_tag="LP386_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HBL1918816.1"
                     /translation="MIGEKMMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVL
                     SASIPILIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEK
                     LLYITKTSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
     gene            complement(895..1152)
                     /locus_tag="LP386_001579"
     CDS             complement(895..1152)
                     /locus_tag="LP386_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918817.1"
                     /translation="MSKLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            1315..2289
                     /gene="bsh"
                     /locus_tag="LP386_001580"
     CDS             1315..2289
                     /gene="bsh"
                     /locus_tag="LP386_001580"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HBL1918818.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
     gene            3019..3336
                     /locus_tag="LP386_001581"
     CDS             3019..3336
                     /locus_tag="LP386_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBL1918819.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNASIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(3540..3905)
                     /locus_tag="LP386_001582"
     CDS             complement(3540..3905)
                     /locus_tag="LP386_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918820.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            4113..4595
                     /locus_tag="LP386_001583"
     CDS             4113..4595
                     /locus_tag="LP386_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918821.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALTVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDSAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            4792..5682
                     /locus_tag="LP386_001584"
     CDS             4792..5682
                     /locus_tag="LP386_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HBL1918822.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            6007..8478
                     /locus_tag="LP386_001585"
     CDS             6007..8478
                     /locus_tag="LP386_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBL1918823.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGHQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKVIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(8581..10317)
                     /locus_tag="LP386_001586"
     CDS             complement(8581..10317)
                     /locus_tag="LP386_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBL1918824.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(10314..11018)
                     /locus_tag="LP386_001587"
     CDS             complement(10314..11018)
                     /locus_tag="LP386_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1918825.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            11149..11652
                     /locus_tag="LP386_001588"
     CDS             11149..11652
                     /locus_tag="LP386_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBL1918826.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            11612..11950
                     /locus_tag="LP386_001589"
     CDS             11612..11950
                     /locus_tag="LP386_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HBL1918827.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            11971..13389
                     /gene="ffh"
                     /locus_tag="LP386_001590"
     CDS             11971..13389
                     /gene="ffh"
                     /locus_tag="LP386_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HBL1918828.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            13501..14079
                     /locus_tag="LP386_001591"
     CDS             13501..14079
                     /locus_tag="LP386_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HBL1918829.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            14083..14604
                     /locus_tag="LP386_001592"
     CDS             14083..14604
                     /locus_tag="LP386_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBL1918830.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(14683..15237)
                     /locus_tag="LP386_001593"
     CDS             complement(14683..15237)
                     /locus_tag="LP386_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBL1918831.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            15490..15765
                     /gene="rpsP"
                     /locus_tag="LP386_001594"
     CDS             15490..15765
                     /gene="rpsP"
                     /locus_tag="LP386_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HBL1918832.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            15777..16028
                     /locus_tag="LP386_001595"
     CDS             15777..16028
                     /locus_tag="LP386_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HBL1918833.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            16153..16944
                     /locus_tag="LP386_001596"
     CDS             16153..16944
                     /locus_tag="LP386_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918834.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            17114..17635
                     /gene="rimM"
                     /locus_tag="LP386_001597"
     CDS             17114..17635
                     /gene="rimM"
                     /locus_tag="LP386_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HBL1918835.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            17625..18386
                     /gene="trmD"
                     /locus_tag="LP386_001598"
     CDS             17625..18386
                     /gene="trmD"
                     /locus_tag="LP386_001598"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HBL1918836.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            18522..18869
                     /gene="rplS"
                     /locus_tag="LP386_001599"
     CDS             18522..18869
                     /gene="rplS"
                     /locus_tag="LP386_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HBL1918837.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            complement(19002..20138)
                     /locus_tag="LP386_001600"
     CDS             complement(19002..20138)
                     /locus_tag="LP386_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL1918838.1"
                     /translation="MWIETKTDKNGKKVYKYNERYIDPKTRKRKKVSITYKNKSRETQ
                     KVALLELNKKIDIKLNEKTLHKPDLTFHELVEEWLVIYKRQVKESTYYPTNNILNTIK
                     KKIPETYIVSGINTIDLNNIFEDMIYKDDLSNKYVSVIKSKLNLLFSYAMKKGYVEKN
                     PIDEVVIDYKRESKTIKIKDKFLEDDEYNRLVDFTTSHNKRYSLLFQWLYLTGMRSGE
                     AIALSKDDVHITNNNASVVINGTMMYRERSIADMKKSDSTKTAAGMREIDLPKKAIAI
                     YNELLELNPNGQFLFQTTKGTPFQLTAINTYLRSHKADMKIDKKLSSHIFRHTHISKL
                     AELGTPLYAIQDRVGHENSDITEKIYLHVTKGVKEKLKEDIEKL"
     gene            complement(20254..20820)
                     /locus_tag="LP386_001601"
     CDS             complement(20254..20820)
                     /locus_tag="LP386_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ltp family lipoprotein"
                     /protein_id="HBL1918839.1"
                     /translation="MAKKVMGQDGKMYKVKKPFYKRVWFWLLAVVVVFIAIGSQGGSD
                     DAKNTVAETTKESVTEVSSAESVAESTVVEEETETTETTIEEVTQEESVPREYRNALS
                     KAESYLGWAGMSEQGLREQLEFEEYPSDAIDYALANVDVDYNEQALAKAESYDDWASM
                     SDSQLYDQLIFEGFTNEQAQYALDNLPQ"
     gene            complement(20956..21609)
                     /locus_tag="LP386_001602"
     CDS             complement(20956..21609)
                     /locus_tag="LP386_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918840.1"
                     /translation="MKKVSVMLLLSTALLLSACSNNKKAESTDTTSNQETKISKTKET
                     TETSSSTSKSTSKTDSSSTVTSSNQATAEPSPTVISSSQSTIQTAPQEETYEQMKQRT
                     LQSTPADRANWSNKEWEAFGVALYENGLTTDDAGNIISQDQKEQQAASQQNPEDQQTS
                     AQQDADTLSLTDFVNKYGMSPVAWKVQNGMSEEEALRTTQQKTSGEVQLGFSKYGIQ"
     gene            complement(21659..22087)
                     /locus_tag="LP386_001603"
     CDS             complement(21659..22087)
                     /locus_tag="LP386_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBL1918841.1"
                     /translation="MEMDTINLVEELKRKYQSANPFYICEKMGIKIQYVPFIENPKGQ
                     FQEIRDRAIIFLNDELRDSEERFYICAHELGHAIFHRGLSSYYVSTRTSRSKSESEAN
                     CFAANLIVSLYKEDNDQYPKKIEELKNLYGLPESAYRFLI"
     gene            complement(22092..22466)
                     /locus_tag="LP386_001604"
     CDS             complement(22092..22466)
                     /locus_tag="LP386_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1918842.1"
                     /translation="MSLVTKIKELADEKHVTIAEVERQVGISNGQIRRWDKASPKSEN
                     LKKVADYFGVTTDYLLGNNNVPKWATKEEVVELDKLLDSNVNMSYGGETLTPEQIQRV
                     KDILIATFWDIVKEDKEKGKKM"
     gene            22770..22955
                     /locus_tag="LP386_001605"
     CDS             22770..22955
                     /locus_tag="LP386_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1918843.1"
                     /translation="MSENLDLKIRAEMRKRRMTFKELAALIGISGAYLSDILNGNRDG
                     KKAQQHIETVKKILDIR"
     gene            22968..23216
                     /locus_tag="LP386_001606"
     CDS             22968..23216
                     /locus_tag="LP386_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918844.1"
                     /translation="MTKLKKQDFVKKYNYSPSTYQRRMSELKNTAIFSAAYERVTGQE
                     VWINTELYDKFLSFKSYNRLRTRKVTPKEFIEKHLVDL"
     gene            23247..23417
                     /locus_tag="LP386_001607"
     CDS             23247..23417
                     /locus_tag="LP386_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918845.1"
                     /translation="MGKFNRALVFSAPLIVYALGLWGSRQALIGTIVYMVWIFIGLDE
                     AEYKTKKPVGRD"
     gene            complement(23519..23977)
                     /locus_tag="LP386_001608"
     CDS             complement(23519..23977)
                     /locus_tag="LP386_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918846.1"
                     /translation="MIKILSDYQVAITLIISISGFFLSLYNLFKDKRKITLSYFLVKH
                     DRSNRMILTGVIANPSKMPNSIIECTYLYNGKKINCSHYHANGFDMGSIHKSSLLSPI
                     PLAQAISPGYSVAFSEVLDMKDILPGEKLVMVIRTANYQKKFKLKLKDSF"
     gene            24145..24462
                     /locus_tag="LP386_001609"
     CDS             24145..24462
                     /locus_tag="LP386_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918847.1"
                     /translation="MLIATDTLDRIFLKDEYKLRNIDASGILVFDLYDNGKIGIYQAS
                     DIEETNLAFEQIDDSVELDLDEAILAFEQIAKLLKEAQKNGNSLPTQRVIYQSPGTGR
                     TIG"
     gene            24395..24874
                     /locus_tag="LP386_001610"
     CDS             24395..24874
                     /locus_tag="LP386_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HBL1918848.1"
                     /translation="MATLYQLSESYIKVLELAEQLDEEILRDTLDSINEAIEYKAENL
                     AKIVKEVEGKAELIDSEIKRLQERKTSLLNNAKSIKHYLQEEMEKTGKTKIKGELFNI
                     GIQNNPVSVNVINENLIPKGFFTPVPPKLDKKQLKEELKHGDIPGAELVQTKGLRIR"
     gene            24891..25067
                     /locus_tag="LP386_001611"
     CDS             24891..25067
                     /locus_tag="LP386_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918849.1"
                     /translation="MEHENVKDALKAAIEIAEAKGIKVDGKPATVHDIQNLTKEHLYF
                     IADLLGLSELYLDK"
     gene            25324..25755
                     /locus_tag="LP386_001612"
     CDS             25324..25755
                     /locus_tag="LP386_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918850.1"
                     /translation="MKNKLAKTTAIIGLALGSGVIGYAASNAFQDLDTIKANFNTVLQ
                     YGQTKSQRVSELESQLSNNTRTQEQLKAEIEQIKSDKQKEIEAKQREIEQKQQEIATK
                     QQEADSLRQQLSTVQNDKEQLEQRVSELRQYTDQKVGELGK"
     gene            25761..26078
                     /locus_tag="LP386_001613"
     CDS             25761..26078
                     /locus_tag="LP386_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
                     /protein_id="HBL1918851.1"
                     /translation="MTIYDPNISWAKHTIKVSFMIWGYKGYVTYKVGGNTKGLSLIAI
                     DSDDLYDANFEDNPVNFRDLDEDWFSMELTNDKGDSTLVEDEFDRLGDYIVGVEIIAH
                     EPE"
     gene            26197..26883
                     /locus_tag="LP386_001614"
     CDS             26197..26883
                     /locus_tag="LP386_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012197638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL1918852.1"
                     /translation="MQIKKATDIEQTKGTYLIYGAPGKGKTSTAKYFPGKTLILDIDR
                     TSKVLRGEKNVDIVYIDNEDTWNDWGNTLADLTTNYVGVYDNVVVDNVSELERCILSS
                     LGAEGKNNGVPSQGDYQYMQFRMVNSLRYMKNLDSNLIWTAWEEIDLWTDSDGSSYNI
                     ALPQINRKIRNNILGLCDVVGRLMVKEDDERGFILQATDSTYAKNQLDNRSGCKQSEL
                     ILYGIVRLPE"
     gene            26858..28207
                     /locus_tag="LP386_001615"
     CDS             26858..28207
                     /locus_tag="LP386_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBL1918853.1"
                     /translation="MELYDYQNDLVDRARQAYVDGYKAPCIVSPCGSGKSVMVAEIAK
                     RTTRKGNRVLFLVHRRELIDQIKDTFQKMGVDNQLVNFGMVQTVVRHLKTIKKPQLII
                     TDENHHGLAASYRKIYEYYSDVPRLGFTATPIRLNGSGLGDVNDLLIEGVSAKWLIEN
                     HRLAPYEYYAPKLIDTAELKKASTGDFTKKSMDKAVKNTIYGDVLKHYKTLAEGEQAI
                     AYCHSIDASKHTAEIFNDAGYKATHIDAKTPKDERADIIEAFRNHEIKILCNVDLIGE
                     GFDVPDCSTVIMLRPTQSLSLYIQQSMRGMRYRPDKTSIIIDHVGNVNRFGLPDMDRE
                     WSLDTKKKTKTDSDLSIVQCAFCFGAYERPKGDNICPYCGELQPIEERKSELEIDESA
                     ELMKVGETKITLNFENNKYYNMTEDEAESIEDLYAIARAKGFKPGWAYMAAKRKGWL"
     gene            28198..28671
                     /locus_tag="LP386_001616"
     CDS             28198..28671
                     /locus_tag="LP386_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBL1918854.1"
                     /translation="MVVGMGGIFGKKAEDVQGSIINGVTIIGDTGKRDSSGNQIVIAR
                     NKNNEVFESSLSNIKRGVVNGTGEESGYVNLKKANEKYHVEGTYVKALSVGGTKGVNW
                     DKRRNKWKARLYFKGEYVLQKDFNTKEEAIQARLAAEEKYFKPILEKYENKKEND"
     gene            28646..29173
                     /locus_tag="LP386_001617"
     CDS             28646..29173
                     /locus_tag="LP386_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF669 domain-containing protein"
                     /protein_id="HBL1918855.1"
                     /translation="MKIKRRMINMTGFNLDFSKAQQGNEIKDGTYEVVVNKAVENATK
                     SGAEFIDIDLIVRNDVDQPFQNKHIFAKIWKAKATGKYNEGMIMAIAQALQLEDGKSY
                     NGFDELLADFVLKTASVRVKTEESNGYKNVNVKSWDKTNTRGVMNHQFKNGDEPSFGP
                     ERSRATTVRNDNLPF"
     gene            29188..31500
                     /locus_tag="LP386_001618"
     CDS             29188..31500
                     /locus_tag="LP386_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBL1918856.1"
                     /translation="MYEKIPKELKNLKQWCVYKLVWDEKRQKHTKIPYNANNGHKAKS
                     NDESTWSDFQTALAAIDHYGMSGLGFFFKPPYFGIDIDNAEGEVERFKSGDIEENIIY
                     EFIESMRSYAEYSQSGTGIHIIARGELPGGRRRKGDVEMYQNGRFFVMTGNAASKYLE
                     ITEPNPKDIKRLYDRYVGDEKIIQFKEENPLMNTVDLPVEEIIKRAESSSQGARFKVF
                     MNGGWEAFYSSQSEADMAFANDLAFWTGRDFEKMDEIFRASAMIRSKYDQKRGSATYG
                     ESLLNKAIADTNSVYNPKRKSDFKIFIKDQEQPKEEKYYSYDDTGNADRFTDIYGTLV
                     KYSYIDKSWYYYDGKVWLQDNTGEVRKMIDTTVDIMGKEPLTIPEGADDETKEALMKA
                     KEKHVKRSRSNAGKNAMMDELKHRLSVLPEEFDKDKTLFNTQSGYLSLHDGLLHEHEI
                     DKMFTRVSNVEYTESVDCPMWEEFINQIFDNDQELIRYIQKCVGYSLTGSTGEQCMFI
                     LYGHGSNGKSVFLEIISELMGNYAMTMQAQTIMVKQSQSSANSDIARLKGARLVTSSE
                     PNEGVRLDEGLVKQLTGGDKVTARHLYGKEFEFEPEFKLWLATNHKPIIRGTDDGIWR
                     RLNLIPFTVQIPDHKKDKNLKFKLQTELQGILKWAIDGCLLWQREGLEKPKSVVAASQ
                     DYRNEMDQIGTFIETCCETGPGLKISGGELYKVYREWASDNGEHTFTNTKFGREISKK
                     YSKEKAGGFMVYKGITLKPRKYDNVRELFK"
     gene            31747..32064
                     /locus_tag="LP386_001619"
     CDS             31747..32064
                     /locus_tag="LP386_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HBL1918857.1"
                     /translation="MKSEHQIQDEIRIALSKHGCTIFRSNAGQVTTIEGRQFYGMPKG
                     FPDLCGHRNSDGKAIYIEVKNERGKLREDQKRFAEFLNGQPVLYGVARSVEEALKIVE
                     ESS"
     gene            32061..>32207
                     /locus_tag="LP386_001620"
     CDS             32061..>32207
                     /locus_tag="LP386_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBL1918858.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIH"
BASE COUNT        10821 a         5465 c         6388 g         9533 t
ORIGIN      
        1 aggggcggta cataaaaatt tattatttag attctataaa catgtgcaac ttatctaaca
       61 acaaagtata tattctacag aagtaaacaa atagcttata ttttaggatg tacacaaatt
      121 gacaagtata ataaaacttt gataaaatac aaatgttttt tatttttatg tgtgattagt
      181 tagaacttac ttaaatccta ttataatatt tttgttaatg attttaataa aatgattgga
      241 gagaaaatga tggatcaaaa agcgtttatc gaatctattg attctacaat cgatagatta
      301 aaaaaagaaa ttcgatttta taatagagta attggtatcg gaaatattat aaaaatagtc
      361 ttatcagcta gtatcccaat attaattgat caggcttccg aacacaggtc tttactattg
      421 attgtttcaa ttgcttcagc aataattaca attatacaaa gtgggatgtc tgcatttaat
      481 tatcaagata aagtacagac ttcgacagag ttattaatga aaattgaaaa agaaaagttg
      541 ttatatataa cgaaaacatc cccatataat aaaacagatg aagaaaattt ccatttaatc
      601 gttacaaccc ttcaaactga attaaatgat attatctctg attttaatca agttaataac
      661 taaaaattta tttaattaga aagtagtgca gataatacta attgtacaat taagaaaaga
      721 gataagactt tacattccta aaaaaatgta aagtcttatc tcttttctta atgctataaa
      781 ttcataataa cattatggac aataaattta aaatttattc agactgtaga caaactccta
      841 aatttagagt gttgtttgca gtctgacgac tcaaaaatga gtcgtataaa tcaattatag
      901 taataagtca ttgatttctt taaattcttt gtcaagttct ttttcatcat atttttcata
      961 tttatcagct tcatgaagaa cttttttaat ttcatgaata gcctttcgtt caactaacca
     1021 tttttttagg ttatgttttt tttctggatt ttcagataac gtatcaagtt cgtctaactc
     1081 tttatccagt ttattgacaa cagaaacaat tttgtttaca actttttctt ctttgttttc
     1141 taattttgac atttatcttc acgtcctttt tatttgataa tttaagtata gaactttgat
     1201 atagtttata caaataaaaa cgcttctttg tgtattctgt gcttttcttt tggaatgagg
     1261 aaaactttgg agtaatatga acgtggacag aaaaatattt aggaggaata aactatgtgt
     1321 acgtctatta cttatgtaac aagtgatcat tattttggaa ggaattttga ttatgaaata
     1381 tcttacaatg aagtagtcac tgttactcca agaaattata agttgaattt tcgaaaggta
     1441 aatgatttgg atactcatta tgcaatgatt ggtattgccg ctggtatagc tgactaccct
     1501 ctttattacg atgcgacaaa tgaaaaagga ttgagtatgg ctgggctaaa tttttctggg
     1561 tatgctgatt ataaagaaat acaagaaggg aaagacaatg tatctccttt tgaatttatt
     1621 ccttggattt taggacaatg ctcaacagta ggagaagcta aaaaattgtt aaaaaatatc
     1681 aatttagcaa atataaatta tagtgatgaa cttcctttat cccctttaca ttggctatta
     1741 gctgataaag aaaaatcaat tgtcattgaa agtatgaaag atggacttca tatatatgat
     1801 aaccctgtgg gcgttcttac caataatcct tcatttgact atcaattatt taatttaaac
     1861 aattatcgtg tcttatcgag tgaaactcct aaaaataatt tttcaaatca aataagtttg
     1921 aatgcctata gccgcggtat gggagggata ggcttgcctg gagatttatc ctcagtatct
     1981 cgttttgtta aagcgacttt tacgaagctg aattctgtat ctggagattc agagtcagaa
     2041 agtattagtc aatttttcca tatcttaggt tcagtagaac aacaaaaagg tttgtgtgat
     2101 gttggtgatg gaaaatatga atatacaatt tattcttctt gttgcaatgt tgacaaagga
     2161 atctattatt atcgaacata tgaagacagt caaattactg caattgatat gaataaagaa
     2221 gacttagata gtcataagtt aattagttat ccaattatag aaaaacaaca aattaaatat
     2281 ataaattagt taatgtgttg tgattgatta tttaatatag atataataca aaaaggcaaa
     2341 gatattttca aaacattttt tcttgatgtg atatccttgt cttttttgta atgtttttaa
     2401 cttattgctt ttgcaaaatt tatttacctg ttttctggat caacgatagt gtatattatg
     2461 ctatccttgt ttggatttta ggacgtttaa agaggcactt ttttacataa cttaatccat
     2521 agacctttta agcatgctgt gagataataa taaagaagag tttaaagcgc accccaaacc
     2581 acttccccat aagtgtatta cgctttaaac tcttttatat ttgaattcac taagaagcat
     2641 accatatttt tgaaaaaaag tgagaaaaaa ggcttataat taggatttag agtaattaat
     2701 tagatgttta ttttatagga ctgatattat agattacaaa tagtatcgta tttcgcaatc
     2761 ttaaaattat cttcttacta tgaataagat aataaaattt gtatttgtcc tttttaggta
     2821 acttatttta atctatatac ctttctggat caacgaaagt atactttata tagtcataac
     2881 gccgatggta actatgcact gtaacgataa tgctgctaaa atatcttttt acgaaaaaca
     2941 tcacaaggaa aaacttaact atggtattat ctaaacataa ttttttcggt atttaatatt
     3001 taattaggag ggaatatttt gcttttttat agtaatttta tcttaatagt agcgatatta
     3061 ttacttctga atatatggat ttttgatagg agtagaaatg caagtatagg ttttagaact
     3121 aaacgaagtc tgtcttctaa aaaaaattgg gtatactcac aaactatttt ttatggagga
     3181 attgttttaa ttagtttact ttcttcaaca ctttattctt tgaatattat agatgtttcc
     3241 acctcaaatt caatatctat tattggaatc attattgctg caattattac acaactgttt
     3301 ttagtgtttg gagagaagaa aagaagtaaa aaatagaaaa actagtgata gttttggtga
     3361 tagtgatatt aaaaatcaga aaagatagaa aaagcaggag atagataaaa tgctgatatt
     3421 tcagcatttt ttaagagtat aaaagagaaa aaaagtaata aatgtataca tgatataaga
     3481 aaaacatata tgtataaaaa gaagaaagta gcttctcttt gtacatatat ggtttgtttt
     3541 tatggatgcc gagctttttt ataagataag gctaccgccc ataacgaccc aaggatttgt
     3601 ggaactaagt aaatacctgc aagaagcaag atcagctggg tcggttttaa aggatgatag
     3661 aagtaacgcc attcagtaaa attggcgcaa aataaatagg aagtgacagt agatataata
     3721 ttggcaatga ataaagatat aatacgcctg ttcctttgaa aataatatcc agcaaaaaga
     3781 gataaaaata tcaatgtgat gaacccgctt acggaatgat aacgaaaatc aagcagtaag
     3841 gcgaaatgca cataaggaac aaaagataaa agcaacggaa ggtttttcca gcaagttttt
     3901 atcatctttc atcaccacct aacaagtgtt attattttgt tagttttatt gtaaattgaa
     3961 tcctgcaata atcaattact ttttcattat ttctagatta aatgaataaa ctctcatgcc
     4021 attatctcta aaaaaaaagt ttttccccct aattttttta gatagaaaat tgtatagtat
     4081 gatgagagaa aaagtagttt gggggaacgt taatgagaag aaaagcagta atcgatcggc
     4141 tttatttatt tttttggttt tttcctatcg ttttgctacc ttttacatgg gtaaatgctg
     4201 ttgtacaagg tgcggagata ttaggcctga tccaaggaag cggatttgtg gtttctagga
     4261 attttccagc tttgactgtt ttctatttag tgataagtgt aggtctctta ttaccaaaat
     4321 ctctgatcaa tcactacaat tggcagctgc tttacttttc ttgcttatta gtatttacat
     4381 ctatgttttc tttgctgcct cgcttgatta tcggccctaa tggtttgagc gagagtggat
     4441 tgaaggattc agcttattcc tccatgtatt tcttgacgat caaaccatgg ttctatttag
     4501 taattgcctc atttattctt gcaacatttt tttacttctg gacagaaatc aggataaaaa
     4561 gtgaacgatc tgtatctata aaaaataact attgatggtg gatcatcagt aaaaaagcat
     4621 atgagctgcg taaaatgcat gtttctcata tgcttttttt attattatgt aaagaatgcg
     4681 aaaaacgttt acatgatttt tacataactt aactatattt ttacagcaac catacgaggg
     4741 atttacagtc gactgataaa ctttagttgt aaataagaaa ggagcaataa aatgaaaaaa
     4801 gtattgttta ctctaggtat gatgggaatt cttttagccg gatgcggctc aggatcagga
     4861 aatacagatg gctctgccac acaaaataat tcaagtgact caaatgaaca agtaaaaatc
     4921 gttgcggtag gttcgacagc attacagccg ttagtcgatg cagcacaaga aagctttgta
     4981 caagaaaatc caaattatca aatctctgta caaggaggag gaagcggaac tggtttgagc
     5041 caagtcgaag ctggagcagt tactatcgga aactctgatg tatttgcaga agaaagagac
     5101 ggagttgatg cttcaaaatt agtggatcat aaagtagcag tggtcgggat ggcgccaatc
     5161 gtcaataaag atacagatgt caaagatatc accaaacagg aattgattga tatctttaca
     5221 ggaaaaatca ctaactggaa ggaagttggc gggaaagatc aaaaaatcaa cgtcgtgaac
     5281 cgtgcaaacg gcagcggtac ccgcgcgaca ttcgaaaaat ggggactgga tggtgctacc
     5341 cctgtgcagt cccaagaaca agattcatca ggaacagttc ggcagctggt aagtcaaaca
     5401 ccaggagcaa tcagctattt agctttctca tatctcgatg attccacaca agcactaagt
     5461 atcgacggtg tagaaccaaa agaagagaat gtagcagata acagctgggg aatctggtca
     5521 tatgaacata tgtacacgaa cggaaaacct tcccctgaag tccaaaaatt cttagactac
     5581 atgatgacag aagaaatcca agaaggacct gtcaaagaat tgggctattt accaatcaca
     5641 atgatggaag tagaacgtga tcacgaagga aatatcaaat aactagcaga taaacatgcc
     5701 acggtagtcg ttactattaa ggaaaaatca actatgtttc ccacatatac atttttcctt
     5761 taattgtgaa aaatagttcc tcatattttg ccgttttttg agctaatacc gagggtcagc
     5821 tgattaaaca ccgtttattc gaaaaaaaga gctacgacat agaactgtcg tagctctttt
     5881 tttgctatat gacaggaatg aaaggtgttt gcaagcttaa tgtgaggaac actttccata
     5941 tctgttctat actggatagg agaagtttgg aaatatccag aaaacgaaat caatcgaggt
     6001 agccacatga agaataaatg gataaatcga agtaaaaaaa agaaagtaac acaaagatca
     6061 tcagataaag tcatccgtct ttttccatcg tataaagaag gattaacggc agatcaagtc
     6121 aaggaacgaa tagaaaaagg tgcagcaaat aattcagtcg atcccacatt caaaacaaat
     6181 cagcaaatcg tattggaaaa catatttacg tatttcaatt tgatctttct tatcttagcc
     6241 attttgcttt gtttagtaga atcctataag aacttgactt ttttaccagt tatcatagcc
     6301 aatacaggaa tcgccatttt tcaggaaatt cgatccaaaa agatcttgga cgaactaaat
     6361 gttttaaata cagcaaaagt caatgtcata cgggacggga tagaacaaac aatagatata
     6421 gaagaccttg taatagatga cattgttatt ttagagactg gacatcaaat tccagcagat
     6481 gcagaggtcg tggaaggaaa actgcaagtt aatgaggctt tattgacagg cgaagcagat
     6541 gaaataacca aagaaatagg cgatccatta atgtccggca gtttcattgt ttccggaaaa
     6601 gcttacgccc gattagacaa agttggagca gattcgtata tttcccagct gacagtcaaa
     6661 gccaagacaa tgggagaagg agaacagtcg gagatgattg cttctcttaa tcaattgatc
     6721 aaatggattg ggatcatcat tattcctatc ggtatcctgc ttttttctca aagttacttt
     6781 tttaatggaa acacgatcaa agaaagtgtc gttgcaatgg aagcagcatt gatcggtatg
     6841 atacctgaag gactgtactt gctgacgacg attgcattag cattaagtgc gactaaacta
     6901 gcaaagcaaa gagttctttt acacaatatg aaaagcattg agacattggc aagggtaaat
     6961 gtcctttgtg tagataaaac aggaacgatc acagaaaata aaatgtctgt tcaaaaagtg
     7021 atcgtctcta aaaaacaaga aataatcagt cagtcagatc aattggaagc atgcattgct
     7081 gactatgcaa aagcgatggc aggagacaat gcaacaatgg aagctgttaa agcatatttt
     7141 acaaaaacca ctgatcaatc ctatcaccat gttattcctt tttcttctgt ccaaaaattc
     7201 agcagtgtag cgttggcaga caaggtgtat gttttaggag cgcccgaaat ggttttgcgc
     7261 gatcaattgc cggaatatgc ggaagagttt gtttctttcg ctgaaaaagg ctatcgcgtg
     7321 ttggtctttg gtgtgtacga tgggattctt gaagaaccag tattgacaga agcagtcaca
     7381 ccattaggct atattctgat tgctaatcct atcagaaaag aagcaagagc cacatttgat
     7441 tacttcaaaa aacagcaagt agccatcaaa gtgatttctg gagataatcc gctcaccgta
     7501 tccaatgtag ctgtccaagc agggatttca catgctgatc agtacgttga tgcatctaaa
     7561 ttatcagaag aagaatatga agcagctgtc gaaaaatata cagtttttgg acgcgtcaag
     7621 ccagaacaaa agaaaatctt cgttcaattg ataaagcgta acaatacagt agctatgaca
     7681 ggtgatggcg tgaatgatat tctagccatg aaagaagcag actgcagtat agcgatggct
     7741 tccggaaatg aagccgccat gcaggcctca caagtggtct tacttgattc tgacttttca
     7801 cgcatgccag aagttgttgc agaaggacgg cgcgttgtga acaatattga gcgatcagcc
     7861 agcttgtttt tagtgaagaa tattttctcc tttttgctct cactgttttc agtgatcttt
     7921 gctctgacct atcctttaga accatcacaa atcacattga ttagtttgtt tactatcgga
     7981 cttccatctt tcttgcttgc tctagaagaa aacaaaaagc gaatcagagg gaaattcatc
     8041 atgaatgtga tggaaaaagc tgtgccaggt ggactaacag atatgatcgt agtcggtgcg
     8101 ttggtgatct gcggggtgac tttgaatcta aataaaacag atgtttctac agcatctacc
     8161 atgcttttga ttgcagtagg gttcctcgtt ctctataaaa tctgttcacc gctgaataaa
     8221 ttcagaagtc agatcattct tttctgtgct agcggtaact ttttttcggt catctttttg
     8281 cataagctgt tttcaatcac cggtatctca gctgtatcac ttttgctgtt gagcattcta
     8341 tttttctcgg cagattcgat ttttaggcat ttgaccacat tggtagaata tttgtttgaa
     8401 cgtaaaaatg aaaaagagca aaagccgttt agtcgcgtag ctaaaaaatt tctatcgata
     8461 tttaaacgag aaaattgacg aaaagtatct caaaaaagag taaaaaagaa caaccactcg
     8521 tgtatctttc gaagcaggat gagtcatcca actttaaaac gcacgagcag ttgctctttt
     8581 ttacattttc ggaatggtaa cggtgaaagt cgaacctgtt ccaagatgac tgtctacagt
     8641 aatcgtacca ttaaggagtt gcacgtagtc ttttacaatc gctaacccta atccggtccc
     8701 gcctgaatgt cggcttcgcg ccttgtctac gcggtaaaaa cgctcaaaga tccgttcctg
     8761 atcctcaatg tcgataccta taccaaagtc ttggacagaa aacgatagat catctgttgc
     8821 ctgatagcgg ataataatct cgctgtcgct ttttgaatat tggacagcat tttcaatcag
     8881 atttttgata attggataaa ggatatctgt tttagtagta aatggttcgt tctttccaat
     8941 caatcgaatc gtcaaccgtt tcttttcgat gattggctga taattttgaa cgatttgctg
     9001 gaaataaggt tctgtataaa ttgtctggat ctcgtaagaa ttctcgccat cttttgacag
     9061 ctggatgatt tcccgaatca gtttatctaa ccggatcgca tctttttgca tgatctcaag
     9121 aaaagaagtc agagtttgcg ggtcatcttt tgcaccatcc agtaaagtct cggtaaaacc
     9181 aatcagtgaa gtcacaggag tttttaattc gtgagagacg ttgccaacga aatccttttg
     9241 tagcttttct aaacgtcgca ctttcgttaa gtcatacgcc acccctagaa tctgtccggt
     9301 accttctgaa ttagtaaagt agcgcaaact caagtctaat gtctgccgac cttctgtaag
     9361 ggtgatctcc tgatggatca gcggatgctc aggagtcact tgatgaatca gctgaatgag
     9421 ttttggctct tgaatgactt ctgtgtaccg ctgttcaggt tgatagctta ccacgtttaa
     9481 atgtagctgc atctttggat taagcagtag taaacgagaa tcagcatcat caatcaggaa
     9541 tacgccaatc atcagttcgt tcagtaacgt atataattgc tcttctgtgg tagtacacgc
     9601 ccgatacatc ttactcattt gttcgctcaa cgcattaatc gtctgataca attcttccca
     9661 ttgatcgggt gtttgcatga ttacttccgc ctgattagga ttttgcacca ttttttttag
     9721 tacgggcagc acggttttca atggctggtt tttttgatag atcagataat agatcattcc
     9781 tgcaagaaca aggaagaaag acagaaagaa gaaaaagacc caacggcgaa aactctcagt
     9841 tctcggtaaa aaaccgcttg tcggttctgc gatacgtaaa atggcttcta actggccact
     9901 ttttttgact ggtaatgcga catataaaag atcctcattc aaagtagtac ttttgcgcaa
     9961 agcgctacct aggttcccac cattcaatac ggctttgatt tcgggacggg agtttcgctg
    10021 ttcattcaat gtttcattgt ttgtgtcaaa taagatcttt ccagtagcat ccattaaagt
    10081 aatccgttcg ttcgactgat ggacgaattc ttccaaagca gttttgtttt gcgctgcttg
    10141 gaggttttcg acatctaatt gccggatcag cagttgtgct ttttttgtca ggtagctttc
    10201 ttgctgttcc acgatctgct gttgaaaata atgggaaatc aattgccagc caccaaaaaa
    10261 caaactaact aaaagaataa gaaagaagag acgttcataa atttttttcc atttcatcgt
    10321 tttggttcct gaaacttata gccaaatcct ctaatagtca ccaagtactt tggatgtttt
    10381 ggatctcgct cgattttttc tcgcaaatga ctaacgtgta catctacgat tcggctttgt
    10441 cctgcgaagt caaaattcca aatgcggtct agcaatgtgt ctcggtcgat cacacggtct
    10501 tttcgtttca tgaaataaac aagtaattca aattctttcg gtgttagttc aatcagatgg
    10561 tcgtctacgg tcacttgata attggtcaaa tcagcagtga tttgtccaat cgatagatat
    10621 tcaggctcag cttcatcttt tgattgctta cgaggttcaa tccgtctgaa tattgctttc
    10681 atacgggcta atacttcgcg aggactaaat ggtttggtca aatagtcgtc agcacctatt
    10741 tctaggccaa tgatccgatc cacttggtca tctttagccg tcagcatcaa aatcggtgtt
    10801 tcattttttt cttgacgcag ccgctgagtg atctccatgc catccatcgt tggaagcatc
    10861 acatctaaaa tgatgaaatc aaatgattgt tctaatgcta attctaatcc ttcgcctcca
    10921 tctgtggcac tggttacctt gtagccttct ttttccaaat tgaacgtcaa gagcgttaca
    10981 atagaaggtt catcatcaac aactagtatt tttttcattc aaatctcctt taaataggtt
    11041 tcattctgtt tatattttag catagaatca gtacaaaggg ctattttaca aaagaaataa
    11101 atggtataat aggaaggcac tttgctgaat agaaaggaag agcagtcaat gattggaatc
    11161 agtgcatgtt taggcggtct ggcctgtcgc tatgatggac agaaaaaaga agtaccagaa
    11221 ttgatggaac tagttgaaac tggagaagct gtcatggtct gtccagaagt gatcggcgga
    11281 ttaccaattc ctagagatcc cgctgaaatc attggtggaa atggattcga tgtgtggaaa
    11341 gatcaagcaa aagtatggac gacaagcggc gaagatgtaa cggaagcgta caaaaatggc
    11401 gcgatcaaag cctatcaaaa attgcaggaa aaacacattg atctagtcat catgaaggaa
    11461 aaaagccctt catgcggaac ccattcgatt tatgacggaa gtttttccgg aataaaaaaa
    11521 aatggtgccg gagtggctac tgcttatttt attcagcaaa aaatgactgt gctctctgat
    11581 gaagaatggc tgaaaactag aggtgagcag aatggaaatc gaaaagacca atcgaatgaa
    11641 cgcgctcttt gaattttatt cgaccttatt gacagaaaaa caaatgaact acatggaatt
    11701 atattatgca gatgattttt cattaggtga gatcgcggaa gaatacgaag taagccgaca
    11761 agcagtatat gacaatatca agcggacaag caagatcttg gaggattatg aaaaaaaact
    11821 ccatcttttt tctaattata ttgttcgaga acaggtattg gaaaatatga ctgcatatat
    11881 tacagataag tacccggaag ataaaaaact acttgaatat gtacagcaaa ttcaagcaat
    11941 cgaagaataa ataaaaggaa tgaagaaaat atggcatttg aaagcttaac tgaacgtctc
    12001 cagcaggcga tgggaaaaat aagaaaaaaa ggaaaagtat cagaagctga cgtaaaagaa
    12061 atgatgcggg aaatccgcct tgccttacta gaagccgatg ttaacttgca agtagtcaaa
    12121 gattttacta agcgcgtacg cgaacgtgcg gtaggggcag aagtgctgga aagtttatca
    12181 cctgcacaac aaatcgtaaa aatcgttgat gaagaattga cgatcacact tggttctgaa
    12241 acagcagagt taaataaatc accaaaaata ccaactgtta tcatgatggc tggtcttcaa
    12301 ggggcaggta aaacgacctt tactggtaaa ttagccaatt atttaaagaa aaatgaaaat
    12361 gctcgtccgc tcctaatcgc aggggacgta tatcgaccag ctgcgatcga ccaattgaaa
    12421 gtattaggtc aacagctaga cgttcctgta tttgatatgg gaactgaagt cagcccggta
    12481 gagatcgtcc gtcaagggat ggagttagca aaagaaaaga aaaacgacta tgtattgatc
    12541 gatacggcag gacgtctgca tatcgatgaa acattgatgg atgagttgaa acaaatcaaa
    12601 gaattgacgc aaccaaatga gattttgctt gttgtcgatg ccatgactgg tcaagatgcc
    12661 gtcaacgtag ctgatagctt caaccagcaa ttaggtatta caggggtcgt catcactaaa
    12721 cttgatgggg atactcgagg cggggcagca ctatcgatcc gctcagtgac aggcgcacca
    12781 atcaaattca tcggttctgg tgaaaaattg actgacttag aagtattcca cccagatcgt
    12841 atggctagcc gtatccttgg tatgggggat atgctgacat tgattgaaaa agcgcagcaa
    12901 gactacgacg agaaaaaagc ggaagaactt gcacagaaaa tgcgggaaaa ttcattcgat
    12961 ttcaatgact ttattgaaca gcttgatcaa gtgatgggta tgggcccact ggaagatcta
    13021 atcaaaatga tcccaggaat gaatcaagtc cctggaatcg aaaacgtcaa ggtagatcca
    13081 aaagatgttg aacgcaaaaa agcgatggtt tattctatga cgccagcaga aagagcaaat
    13141 cctgatctgt tgaacccaag ccgtcgtcgc cgaattgctg ccggttctgg aaacagtgtt
    13201 gttgaagtga atcgaatgat caaacaattc aaggaatcaa gaaaaatgat gcagcaaatg
    13261 tccaaagggg atatgaacat cccaggtatg gaccaaatgt ttggttcagg cgtcaaagga
    13321 aaactaggca aaatggcgat gaatcgaatg atcaagaaaa ataagaagaa aaagaaaaaa
    13381 cggaaataag atgaaaaaaa cagcttcggt acagactgaa aatgtctact gccggagctt
    13441 ttctatcagc aatttttatt ctttactaat acaattactc taaacgaaga ggtggcacag
    13501 atgagatgtc cgtggagtga acaaacagaa agtatgcggc aatatcatga tactgtctgg
    13561 ggtgttcctg aatatgatga ccaaaagctg ttccgaaaat tgatgcttga tattaatcaa
    13621 gccggattga gctggcagac gattttaaat aaaagtgaag cattcgatga agcatatgat
    13681 cgattcgata tcaaaaaagt cgcaaattat ggagaaacaa aaatcagtga actaatggaa
    13741 aacaaaggaa ttattcgtaa ccgaagaaaa atcgaagcag ccgtccaaaa cgccaaagca
    13801 gtcttgaaaa ttcaagaaga aatcggcagt ttttcagagt atctttggtc gttttctaat
    13861 ggaaaaatcg ttgattcttc ttatcattca caagaagaag tcccaacaac aagtcctctt
    13921 tcagatgaat tagcaaaaga tctaaagaaa agaggattta aatttatcgg aagcacaaca
    13981 atctatgctt ttttagaagc tgtcgggatc atcaatgatc accttgacag ttgtttccgc
    14041 aaagaagagg tcgtacgtat cggcagaaag ggcgaataaa gcatgcgaaa aatcatattt
    14101 tatggtgcta taagtttaga tggctatttg gcaacgaaaa cggatgatct tcaatggctt
    14161 tttgacactc caacaggtaa gcaaactact tatgaagctt tttatgaaac aatcgatacg
    14221 accatcatgg gcagaaaaac ttatcaggaa gcaaaaaaat atttggagac cgaagcaatt
    14281 tatccagaga aaaagaattt cgttttttcc acccacgcac aattacaatt gccagatgct
    14341 gaggtcgtaa acgaagatcc tgttgctttt ctaaaaaatc tacaaatgac agaaggaaaa
    14401 gatatctggg ttgtgggtgg cggtcgattg atcaaaccgc tattggaaca tcaaatgatt
    14461 gatgaatggt atatccagat tacccctgta ttattagggg acgggattcc tttattccaa
    14521 aaaggaacat atgaagcgcg ttttgaaatg ctagacacga cacgattcgg tgaatttatc
    14581 gaattgcatt atgtacgaaa gtagaagtaa ataaaataaa aaaggcaact atatgcagaa
    14641 atgtcctgta catagttgcc ttttttatta ccgttatgct ttttactctg ttaatttgtt
    14701 agaaaaatct agatacgcat ctaaaatcgt ttggaagaaa cttaatgttc cttcaacgat
    14761 attaccattt tcatcaatta gattcgcaac gtttccgata tatgcttccg gttgctgcaa
    14821 ggttggcaca ttcaaaaaga caagtgattg gcgtagatgg tggtttgcgc caaagccgcc
    14881 gatcccacct ggtgatgcag taacgactaa acctggttta tgatcccaaa cactgtgtcc
    14941 ataaggtctt gagcctacat ctaaagcatt tttcaatact gctggcacag aacggttgta
    15001 ttcaggagta acgaaaacga caccgtctag tcccctcact tcctcacgaa aacgagtcca
    15061 ttcagcagga gcctgttctg gagtttcgag atcctcattg taaaatggca gatcatcgat
    15121 ttttacaaat acactttcgt acccttcagg aagcaatttc gcaaaagctt ctgctacttt
    15181 tttgttgtaa gaatcttttc ttaaactacc aataaaaaat ccaatttttt ttgtcatacg
    15241 atttttcctc cttcaaacta tctataataa tcttacaaaa gataagtaac tggagcaaat
    15301 aaaaacactt actgacaaaa gctacataga agatagatta cttattttta acaaaaaaga
    15361 agtctaaaat cttctatttt ctaaaaaaaa tcgaatttaa tcaagctgta aagaaaaaaa
    15421 gctttacagg gtaaaaaaaa actgttacac tacatcttgt gaataaaaca atggaggtgg
    15481 aaataaataa tggcagttaa aatccgttta aaacgtatgg gttctaaaaa gagtccgttt
    15541 taccgtatcg tcgtagctga ttcacgttct cctcgtgatg gacgtttcat cgaaactgta
    15601 ggtacttaca atcctttgaa agaccctgca gaagtagttt taaaagaaga cttagttctt
    15661 gactggttat caaaaggtgc acaaccttct gacactgtac gtaacatcct ttcaaaagaa
    15721 ggcgttatgc aaaaacacca cgaagctaaa ttctcaaaga aataaggtga ccggatatga
    15781 aagatttaag cgacttagtc ttaacaatcg ttcgtccgct agtcacttat cctgatcaag
    15841 tcaagttaga cgtcgtagag tcgaaagact tttacgagta caatctaaca gtggctcctg
    15901 aagatattgg ccgtatcatt ggaaaacaag ggcgtgttgc taaagcaatc cgcacaatcg
    15961 tttacggtgt tcggatcaat gcaccgaaaa aagtgcgttt gaatatcatc gatgataagg
    16021 aaaagtaaat aaacgtgctg tactcgaatt ttcgagtgca gcttttttgt tttttttatt
    16081 aattgaagaa atgattattt ggcaaaacaa gcaagaaagc gtatccttat aggaggaggg
    16141 agtgaacagc caatgagaaa gaaaatgtta tttattccat ttgctctatt gttaagcgct
    16201 tgtagttcgg ttactcaaga atcagacaat acacatctat caagcagtat atctgaaact
    16261 gttaccagtc cagaaaaaag tagtaccaaa acggcttcca ccactgaaca aacaatggct
    16321 acctcaaata atgagaaaaa gactgcttta gaccagttga aagaacaaca gccaaatgtt
    16381 cccatgcctc tagatgtacc agtctcttca ggctatctca atatcgcagc gacacataca
    16441 aagcaaggtt attctatttt atattacaga acagatcgtc ccctcgggtt gaatgctgac
    16501 gaattgaatc aagaaacgcc tattgcaacc tatctatatc aatatgggtt tgcttctagt
    16561 caagaaacaa tccaagtttt gcagccattt gagatcgaca caaatggtca gcaagtggac
    16621 ttaggttctc gaatcacagg gtatcagcaa ggtgcagcag gttcaagttt tcttgaatgg
    16681 caagaaggaa actggcgtat tcgaatccgt gggaataata tagaaggcca agatccctta
    16741 ctattagcta aagaaatcgt agcttatttg gaagaaaaca gtctaccagc acctgaacaa
    16801 tttggtaaaa ttactgttga tatgggtgat acgacgaatc gagccgtaga agtaagctgg
    16861 caagaaccga aaaatgccta tacgatcact catcaagatc ctatgtctgc gttgaagatg
    16921 gcagtttcta tgaagaggtt gtgaaatcag cgcgctgatc tgagcccatc atttaactcc
    16981 aagtcacagg aagtaatcaa aaatagcacg ccgcattttt gcataatttt ggcttaatac
    17041 cttaaaagaa aactagaatt gcctcttcac acatgctaaa ataaaacaga caaaaaagaa
    17101 atggggatat aagttgactg aatacttgaa tgtaggaaaa atcgtaaaca cacaaggtat
    17161 caaaggcgaa gtccgtgtta tctcaacaac ggatttccca gaagaacgtt acaaaaaagg
    17221 aacggtgcta acactattcc aagacggaaa agcacctgtg gaattaacag tcaaaagtca
    17281 tcgcaaacat aaaaattttg acttattgag ttttgaagga catccttcta tcaatgatgt
    17341 ggaaaaatat cgggatggca tattaaaagt gtcaaaagac aactctgtag atctagctga
    17401 aaatgaattc tattaccatg agatcatcgg tctgcatgta ttagaagatg gaactgagtt
    17461 aggtaaagta aaagaaatct tgtcaccagg tgccaatgat gtttgggtcg ttcaacgtcc
    17521 gaaaaaagct gatatattgc ttccatatat cgcttctgtc gtcaaagaag tcgatttaga
    17581 agctggagtg gtccgtgtag aaattccaga aggactgatt gacgatgaag attgatgtat
    17641 tgactttatt tccaagaatg tttgaaggtc ctatggggga atccatcatc ggtaaggctg
    17701 tagataaagg attattagat atcaatatct ctaacttccg cgattattca gataacaaac
    17761 atcagacagt agatgattat ccatacggcg gtggagcagg tatgctgctc aaagtccagc
    17821 ccatctatga taacatccaa gccattgaaa aagctgcacc ggatgtcaaa aaaagagtaa
    17881 ttcttcttga cccagctggt aaacgattcg atcagaaaat ggcagaagaa ttttcacaag
    17941 aagaacactt agtattcatt tgtggtcatt atgagggata tgatgaacgt atccgcacat
    18001 tagtgacaga tgaagtttcc ttaggagatt atgtccttac tgggggagaa ttaggtgcga
    18061 tggtcatgat cgatgcaaca gttcggcttt tgccagatgt gttagggaat cagacttcag
    18121 ctcaaacgga ttcttattca accggtttat tggaacatcc ccaatatact cgcccggcag
    18181 aatataaagg gatgaaagta ccagaagtat tgacaaatgg aaatcataaa ttgattgaag
    18241 aatggcaatt aaaagaatca ctaagaagga cctatcaacg tcggcctgat cttttggaaa
    18301 cacttgaatg gacacctcaa atgacgaaat ttttagaaga aatcaagaaa gaagaacaag
    18361 aaaaaacagc agatgaagcc aagtgacttt ttctaaaatc ttctttacag taggttgata
    18421 atatgttagt attttatggt gagtgcaaaa gcacttaact attacgatat tccgctgtga
    18481 gaaaagctca taagaatatt tggaataagg agaagaaaac catgaatcca ttaatcgaag
    18541 aattaacaaa agaacaatta cgttctgaca tcccagcgtt ccgccctggt gacactgtgc
    18601 gtgttcacgc aaaagttgtt gaaggtactc gtgaacgtat ccagttattt gaaggtgttg
    18661 ttatcaaacg ccgcggtgct ggaatcagcg aaacttatac agtacgtaaa gtttctaacg
    18721 gagtgggcgt tgaacgtaca ttcccattgc atacaccacg tgttgcaaaa atcgaagtag
    18781 ttcgctacgg taaagtacgt cgtgcaaaat tgtactacct acgtgcatta cacggaaaag
    18841 ctgctcgtat caaagaaatc cgtcgttaat catcgttatc agacagagaa agaacccttg
    18901 gtattcaagg gttctttttt ttattatctg tttttttata ttaacgattt ctatttggta
    18961 catttttgat taataaaaag gggcaaaaaa ggggcaacaa gttacagttt ttctatatct
    19021 tctttcaatt tttcttttac tccttttgtc acatgcaaat aaattttttc agtgatatca
    19081 ctattttcgt gaccaacgcg atcctgaatg gcatacagag gagttcctag ttccgctaat
    19141 tttgaaatat gggtatgtct aaaaatatgt gaactaagtt ttttatcaat cttcatgtca
    19201 gctttatgac ttctcaaata ggtgttaatt gctgttagtt ggaaaggagt tcctttcgtt
    19261 gtttgaaata gaaattgacc atttggattt aattctagaa gctcattgta aatagctatc
    19321 gctttttttg gtaaatcaat ttctcgcatt ccggcagctg tttttgtaga atcagatttt
    19381 ttcatatcag ctattgaacg ttctctatac atcatcgtcc catttataac tactgatgca
    19441 ttattattgg taatgtgtac atcatcttta cttaatgcga ttgcttcacc agacctcatc
    19501 ccagtcaaat atagccactg gaaaaggaga gaatatcttt tattgtgtga agttgtgaaa
    19561 tctactagtc tattatattc atcatcttct aaaaatttat ctttaatttt tatcgttttt
    19621 gactctcttt tataatcaat aactacttca tcgataggat ttttttctac ataacctttt
    19681 ttcatagcat atgaaaaaag aagattcaat ttggatttaa ttacactgac gtacttattt
    19741 gacaagtcat ctttatatat catgtcttca aaaatattat tcaaatctat tgtattaata
    19801 ccagaaacga tgtaagtctc aggtatcttc ttctttatag tgtttaatat attattcgta
    19861 ggataatatg tagattcctt aacttgtctt ttgtatataa ctaaccattc ttcaacaagc
    19921 tcatgaaatg ttagatcagg cttatgaagt gttttttcgt ttaattttat atcaattttt
    19981 ttatttaact ctagcaatgc cactttctga gtttctcgag atttattttt ataagtaatg
    20041 ctcacttttt ttctttttct agtttttgga tcaatatatc gctcattata tttatatact
    20101 ttttttccgt ttttatcagt tttagtttcg atccacattg ttttcatctc ctatttgttg
    20161 ctataatagg aatagataag taagccgatt atagcaggtt tatttttcat cacgtccaca
    20221 aactttggcg agggaggggc gtgtttttgt tagttattgt ggtaggttat ctaaagcgta
    20281 ttgtgcttgc tcatttgtaa aaccttcaaa tataagttga tcgtacaatt gcgaatctga
    20341 cattgatgcc caatcatcgt aactttccgc tttagccaaa gcttgttcgt tgtaatcgac
    20401 atcaacatta gccagcgcat aatcgattgc atcacttgga tattcttcaa actctagttg
    20461 ttcacgcaaa ccttgttcag acataccagc ccaacctaga tagctttcag ctttgctcaa
    20521 tgcatttctg tattcacgag gaacactttc ttcttgagta acttcttcta tagtagtttc
    20581 agtagtttca gtttcttctt caacgactgt agattctgct accgattctg cagaagacac
    20641 ttctgtcacg ctttctttag ttgtttcagc gacggtattt ttagcatcat cactgcctcc
    20701 ttgcgaacct atagcaataa acaccacaac aaccgctaac aaccaaaacc atacccgttt
    20761 ataaaacggt ttcttaactt tatacatttt cccatcttga cccataactt tttttgccat
    20821 ttaaatatcc ctcgcttctt gttataatat atttgtgatc tcagaaatga ggtatgagtc
    20881 cgtgttgcag cacgggcttt tttctttata acttttttag agattatagg caaaatagta
    20941 gggcataaaa atgtattatt gaattccgta tttagaaaat cctaattgaa cttcaccgga
    21001 agtcttttgc tgtgttgtac gcaatgcttc ttcttcagac attccattct gtactttcca
    21061 tgcaacaggc gacatcccgt atttgttaac aaaatcagta agtgataaag tgtcagcgtc
    21121 ttgctgagcg cttgtttgtt ggtcttctgg attctgttga gatgctgctt gttgttcttt
    21181 ctgatcttga ctgataatat tgccagcatc atctgtagtc aatccatttt cataaagggc
    21241 cacgccgaaa gcttcccact ctttgttgga ccaatttgca cgatcagctg gagttgactg
    21301 taaagtgcgt tgtttcatct gttcatatgt ttcttcttga ggtgcggttt ggattgtact
    21361 ctgactggag cttataactg ttgggctagg ttccgccgta gcttggttgg agcttgtaac
    21421 tgttgaacta gaatctgttt tagatgtaga tttgctagta gatgaactgg tttcagttgt
    21481 ttcttttgtt ttacttattt ttgtttcttg gttagaagtg gtatctgttg attcagcttt
    21541 tttattattt gaacaagctg aaagtagcag agcagtactt aacaacaaca taacgctaac
    21601 ttttttcatt ttataattcc tctttctcgt tgtaatatgt gtgctaacac gggctttttt
    21661 atataagaaa acgataagcg ctttctggaa gcccgtaaag attctttaat tcctcgattt
    21721 ttttaggata ttgatcatta tcttctttat aaagagaaac aatgagatta gcagcaaagc
    21781 aattagcttc gctttcagat ttgcttctag atgttcttgt tgatacataa tagctggata
    21841 agccacgatg aaaaatagcg tgacctaatt cgtgagcgca aatgtagaat ctttcctcag
    21901 agtctcgcag ttcatcattt aaaaagatta tcgcacgatc tctaatttct tgaaactgcc
    21961 ccttgggatt ctcgataaaa ggaacgtatt gaattttaat gcccatcttt tcacaaatat
    22021 aaaaaggatt agcggactgg tatttccgct tcaactcctc gactaaatta atcgtatcca
    22081 tctccataag ctcacatctt tttgcctttt tctttgtctt ctttcacaat atcccagaaa
    22141 gtcgctatca ggatatcttt tacgcgctgt atttgttcgg gtgtcaatgt ttccccacca
    22201 taagacatat taacatttga gtctagtagt ttatcaagtt caaccacttc ctcttttgta
    22261 gcccacttgg gaacattatt atttcccaat aaataatcag ttgtgacacc aaaataatca
    22321 gcaactttct ttaagttctc agattttggc gaggctttat cccatcttct tatttgtcca
    22381 ttagagatgc ccacctgtct ttctacttct gctatagtca catgcttttc gtctgctaat
    22441 tctttaatct tagtaactaa actcattatt atcaaccttt caaagctgaa aagaaaataa
    22501 atagcttaaa agttatattt ttggttgaca attagctttt aagctagtat atttaattcg
    22561 taagctaaat tgttagctaa ataagagcaa caaaaaactc tactaattta aaacattctc
    22621 tcggtcgcca aacttagaaa tgttatttta gaggcttttt ataagtctta tttaactatg
    22681 tattcataat agcttaaaag ctaataggtg tcaacgattt agctaatttt ttagcttaca
    22741 aattatttgt ttagaaagga gctattttta tgtctgagaa tttagactta aaaattcgag
    22801 cggagatgag aaaaagaaga atgactttca aagaactagc tgcgcttatc ggtatttcag
    22861 gagcttattt atcagatatt ctaaacggca atcgtgatgg aaagaaagca caacagcata
    22921 tcgaaacagt gaaaaaaata ttggacatcc gatagggggg gtaggcgatg acaaaactaa
    22981 aaaaacaaga ttttgtaaaa aaatataatt attctccatc tacttatcaa cgtcgaatgt
    23041 cggaactaaa aaatacagca attttctcag cggcgtatga acgggtcaca ggacaagaag
    23101 tttggatcaa tacagaatta tacgataaat ttttgtcttt caaatcctat aacaggttac
    23161 gcacaagaaa ggtaacacct aaagaattta tcgagaagca tttagttgat ttataaaaaa
    23221 cagaacattt tgagaggtga aggttaatgg gtaaattcaa cagagcatta gtattcagcg
    23281 caccgctaat cgtctatgct ttagggcttt ggggaagtag acaagcgttg ataggaacga
    23341 ttgtgtacat ggtttggatt tttatagggc tggatgaagc tgagtacaaa acaaaaaagc
    23401 cagtcgggag ggactgacta atgagtaagg acgatattgt atttctgtta attatgtttt
    23461 gtgggattgg atcaataata attaatttgt atttgattat taaagaaaaa tttttcaatt
    23521 aaaatgagtc ttttagcttt aacttaaatt ttttttgata attagctgtt cttatgacca
    23581 ttacaagttt ttcaccaggt aatatatctt tcatatctaa aacttctgaa aaagcgactg
    23641 agtagccagg agagattgct tgtgccaacg gtataggaga taaaaggcta cttttatgaa
    23701 tgcttcccat atcaaaacca ttggcgtgat aatgtgaaca attaattttc ttaccgttgt
    23761 aaagatacgt acattcgata attgagtttg gcatttttga tgggtttgca attacgccag
    23821 taagaatcat tcgattactt ctatcatgct taactaaaaa ataggagagc gtaatttttc
    23881 ttttatcttt aaataagtta tagagggata aaaaaaatcc tgaaatagaa atgattaaag
    23941 taatagcgac ttggtaatcg ctcaaaattt ttatcaagta attcaccacc tttttactca
    24001 aattatatca aaaaggagag aagaaataat gcaagaatta gtaattttga aaaataaaaa
    24061 aagacacgaa cgccggcaag catgatcgtg tcagggaaat aaactatctt tctatatttt
    24121 accacagaaa ggaatgaacc gtaaatgcta attgcaacgg atacactaga ccgcatcttt
    24181 ttaaaagacg aatacaaact gcgcaatata gatgcgtcag gaattttagt atttgatctt
    24241 tatgacaatg gaaaaattgg tatctatcaa gcaagtgata ttgaagaaac aaaccttgct
    24301 ttcgaacaaa ttgatgattc tgtggaattg gatttagatg aggcaatcct agcttttgaa
    24361 caaattgcaa aattattaaa ggaggcacaa aagaatggca actctttacc aactcagcga
    24421 gtcatatatc aaagtcctgg aactggcaga acaattggat gaagaaattc ttcgcgatac
    24481 tctcgattcg attaatgaag cgatcgagta taaggcagaa aacttagcaa aaatagttaa
    24541 agaagtagaa gggaaagctg agttaatcga tagtgaaatt aaacgtctgc aggaacgtaa
    24601 gacatcgctt ttgaacaatg ctaagagtat caagcactat ttacaagagg aaatggaaaa
    24661 gactggtaaa acgaagatta aaggtgaatt attcaacatt ggaattcaaa ataatccagt
    24721 atcggtcaat gtaatcaatg agaacttaat tccaaaagga ttctttaccc ctgtgcctcc
    24781 caaattggat aaaaagcaat tgaaggagga actgaagcac ggagatattc ctggtgctga
    24841 actcgtccaa acaaaaggtt tgaggataag atgatgaagg aggagaaata atggaacacg
    24901 aaaacgtaaa agacgctttg aaagctgcta tcgaaatcgc ggaagctaaa ggaataaagg
    24961 ttgacggcaa accagcaact gtccatgaca ttcaaaattt gacgaaagaa catctttatt
    25021 ttatcgccga cttgcttggt ttgtcggaat tgtatttaga caaataaccc cacacggaag
    25081 gagtggctag ggtggttgta ttacaagtaa tagtctgcgt aacattcatt tggtcgtgca
    25141 taccggtttg tatatatatc atgaagaagc ttcgccctga gtcttacaaa ttatacgcaa
    25201 tttacagcat aacagtagct cttgcattta cattgtttgc aatttctagg cttccgtttt
    25261 aatcgtggga atgaattttt aatgaactaa attatctata aagcaaaaaa aggagaaaca
    25321 acattgaaaa acaaactagc aaaaacaaca gcaatcatcg gactagcact aggtagcggc
    25381 gttatcggct acgcagcaag caatgcgttt caagatttgg acacgatcaa agcaaatttc
    25441 aacacagtcc tacaatacgg tcaaacgaaa tcgcaacgtg tgtcagaact tgaatcacag
    25501 ctatccaaca acactcgcac acaggagcag ctgaaagccg aaattgagca aatcaaatcg
    25561 gacaagcaga aggaaattga agccaagcaa cgagaaatcg aacaaaagca acaggagatc
    25621 gctacaaagc aacaggaagc cgatagcttg cgccaacaac tatccacagt gcaaaacgac
    25681 aaggagcagt tagaacagcg cgtgagcgag ttacggcagt atacggatca aaaggtaggg
    25741 gagttgggga aatgaaagag ttgactattt atgacccaaa tatttcatgg gctaaacaca
    25801 caattaaagt ttcttttatg atttggggtt acaaaggata tgttacttac aaagtgggcg
    25861 gtaacactaa gggtttatca ttaatagcta ttgattcaga tgatctatat gatgctaatt
    25921 tcgaggataa cccagttaat ttccgtgacc ttgatgaaga ttggttctct atggaactta
    25981 ctaacgataa aggcgacagt acacttgtag aagatgaatt cgacagacta ggtgattata
    26041 ttgtcggtgt tgaaattatt gcgcacgaac cagagtagga gagtgaatac aaaatgatta
    26101 aaagaatcac tatatcagtt gaagaagata gtggatcaac aatgcagcat accgacaatc
    26161 gaaaaacttt tttaaccaat agaaaggaga attttgatgc agattaagaa ggcgacggat
    26221 atcgaacaaa ccaagggaac atatttgatc tacggtgctc caggaaaagg taaaacttca
    26281 acggctaaat attttccagg gaaaacactg atccttgata ttgatcggac ttcaaaagtc
    26341 cttagaggtg agaaaaatgt cgatatcgta tatatcgaca acgaagatac ctggaacgac
    26401 tggggcaaca cgttggctga tttaactacc aattatgtag gtgtttatga caacgtggtt
    26461 gtcgataatg tcagcgaatt ggaacggtgt attctgtcca gtttaggcgc agaaggaaaa
    26521 aacaacggcg ttccttcgca aggcgattat caatatatgc aatttagaat ggtgaacagc
    26581 ctacgctata tgaaaaattt agacagcaac cttatctgga ccgcatggga agaaatcgat
    26641 ttgtggacgg attcggatgg atcttcttac aacatcgctt tgccgcagat caatcgaaag
    26701 attcgaaaca atattttggg attatgtgac gttgttggtc gattgatggt aaaggaagac
    26761 gatgaacgcg gatttatttt acaagccaca gattcaacct atgccaaaaa tcaattggat
    26821 aatagatctg gctgtaagca aagtgagctg attttatatg gaattgtacg actaccagaa
    26881 tgatttagtc gatcgtgcaa gacaagccta tgttgatggt tacaaggcac catgtatcgt
    26941 atcaccgtgc ggttctggaa aatcagtcat ggttgcagag atcgctaaac gaaccacacg
    27001 aaaaggcaac agagtgttgt tcttggtcca tcgtcgtgaa ttgattgatc agatcaaaga
    27061 tacgtttcaa aagatgggcg tagataatca gcttgtaaat ttcggcatgg ttcaaacagt
    27121 cgtacgacat cttaaaacca tcaagaaacc acaactgatc atcactgacg aaaaccatca
    27181 cgggttagca gcgtcctaca gaaaaatcta tgagtattat tcggacgttc cgcgattagg
    27241 ttttaccgcg acacccatcc ggttaaacgg tagtgggttg ggggatgtga acgacttgct
    27301 aattgaagga gtatcggcta aatggttgat tgagaatcat agattagctc cttatgaata
    27361 ttatgcacct aaattgatcg atacagccga attaaagaaa gcttcgactg gagattttac
    27421 aaagaaatca atggataagg cagtgaagaa tactatttat ggcgacgtgt tgaaacatta
    27481 taaaacgtta gcagaaggtg aacaggcaat agcatactgt cacagtatcg atgcaagtaa
    27541 acacactgct gaaatattca acgatgctgg ttataaagca acacatatcg atgcaaaaac
    27601 tccaaaagat gaacgtgcag atattatcga agcgttcaga aatcatgaaa ttaaaatcct
    27661 atgcaatgtt gatttgatcg gagaagggtt tgatgttcct gattgttcga ctgtaattat
    27721 gttgagacct actcaatcgt tatcattgta cattcagcaa tcgatgaggg ggatgcgtta
    27781 ccgaccagat aaaacgtcaa tcatcattga ccatgtgggt aatgtgaacc gttttggatt
    27841 gcctgatatg gatcgtgaat ggagtttaga tacaaaaaag aaaacaaaaa ctgatagtga
    27901 tttatctatc gttcaatgcg cgttttgttt tggtgcttac gaacggccaa aaggcgataa
    27961 tatttgtccg tattgcggag agttgcagcc gattgaagaa cgaaagtcag agttagaaat
    28021 cgatgaatcg gctgaattaa tgaaagtcgg agaaacgaaa attactttga attttgagaa
    28081 caataaatat tacaacatga cggaagatga agcagaaagt atagaggact tatatgccat
    28141 agcaagagct aaaggattta aacctggttg ggcttatatg gctgctaaga ggaaggggtg
    28201 gttgtaggaa tgggcggtat ttttggtaaa aaagcagaag atgttcaagg ttcaataata
    28261 aatggcgtaa caataatagg tgatactgga aaaagagata gttcaggcaa tcaaattgta
    28321 atcgctagaa ataaaaataa cgaagttttt gaatcttctc tatctaatat aaaaagaggt
    28381 gttgttaacg ggacaggcga agagagtggc tacgttaatt taaaaaaagc taatgaaaaa
    28441 taccatgttg aaggaactta cgttaaggct ttgtctgtcg gtggaacaaa aggcgttaat
    28501 tgggataaac gaagaaataa atggaaagca cgattatatt tcaaaggaga atatgtctta
    28561 caaaaggatt tcaacaccaa agaagaagca atccaagcac gacttgcagc agaagaaaaa
    28621 tatttcaaac ctatcttaga aaaatatgaa aataaaaagg agaatgatta acatgacagg
    28681 atttaactta gacttttcaa aagcgcaaca agggaacgaa atcaaagacg gtacgtacga
    28741 agtggtcgta aacaaagctg tagaaaatgc aactaaatca ggcgcagaat ttatcgatat
    28801 cgatttgatc gttcgtaacg atgtggatca accgttccaa aataaacaca ttttcgcaaa
    28861 aatctggaaa gccaaagcta ccggcaaata taacgaaggt atgatcatgg caattgcaca
    28921 agcgctacag ttggaagacg gaaaatcata taacgggttt gatgaattgc tggcggactt
    28981 tgttttgaaa accgcctcag tacgcgtgaa aactgaagag tcaaatggat ataaaaacgt
    29041 caatgtgaag tcttgggata aaacgaacac acggggcgta atgaatcacc aattcaaaaa
    29101 tggtgatgaa ccatccttcg gaccggaacg ttcaagagcg acaacggtta gaaatgacaa
    29161 tcttccattt taattgaggt gtaatcaatg tatgaaaaaa ttccaaaaga gcttaaaaat
    29221 ctcaaacaat ggtgtgttta taagctagtt tgggatgaaa agcggcagaa gcacacgaag
    29281 atcccttata acgccaacaa cgggcataaa gccaaatcca atgacgagag tacctggtct
    29341 gattttcaga ccgctctcgc tgctattgat cactacggaa tgagtggact ggggttcttt
    29401 ttcaaaccac cttatttcgg cattgatatc gataatgctg aaggtgaagt tgagcgattt
    29461 aaatcaggtg atatagaaga aaatattatc tatgaattta tcgaaagcat gagatcctat
    29521 gctgagtatt ctcaatcagg tactggcatc cacattattg ctcgcggaga attgcccggc
    29581 ggaagacgca ggaaaggtga cgtagaaatg taccagaacg gccgattctt cgttatgact
    29641 ggaaatgccg catcaaaata tttagaaata actgagccga atccaaagga tatcaaacgc
    29701 ctatatgatc gctacgttgg agatgaaaaa atcatccaat tcaaagaaga aaatccgctg
    29761 atgaataccg ttgatttacc ggttgaagaa attatcaaac gtgctgaatc gtcttcccaa
    29821 ggggcaagat tcaaagtctt tatgaacggc ggttgggaag ctttttattc ctcgcaatcc
    29881 gaagcggata tggcgttcgc caacgacttg gctttttgga ccggtagaga ctttgaaaaa
    29941 atggatgaga ttttcagagc gtctgcaatg atccgtagca aatatgacca aaaaagggga
    30001 tcggcaactt acggagaatc tctactaaat aaggcaattg ctgatacaaa ttccgtctac
    30061 aaccccaaac ggaaatctga ttttaagatt tttatcaaag accaggaaca gccaaaagag
    30121 gaaaaatact attcgtacga cgacaccggc aacgcggatc ggtttactga tatctacgga
    30181 acgttagtca aatattcgta cattgataaa tcttggtatt actacgatgg gaaagtttgg
    30241 ctacaggaca ataccggcga agttcggaaa atgatcgata cgacagtaga catcatggga
    30301 aaagaaccgt taacgatccc tgaaggcgca gacgatgaaa ccaaagaagc tttgatgaaa
    30361 gcgaaagaaa aacacgtcaa gcgttctcgc agcaatgccg gaaaaaacgc tatgatggac
    30421 gaattgaaac atcgactatc cgtattgccg gaagagttcg acaaagataa aacgctgttc
    30481 aacacacaaa gcggctatct gtctttgcat gacggtcttc tacacgagca tgagatagac
    30541 aaaatgttta cacgtgtttc aaatgtcgag tacacagaat cggtcgattg tcctatgtgg
    30601 gaagaattta ttaatcagat ttttgacaat gatcaagaat taatcagata tatccagaaa
    30661 tgtgtcggat attccctgac cggatctacc ggagagcaat gtatgttcat cctctacggt
    30721 catgggtcaa atggaaagtc ggtatttttg gaaattattt ctgaattgat gggaaactat
    30781 gcgatgacta tgcaggcaca aacgatcatg gtcaagcaaa gccaatcatc agcaaacagt
    30841 gatattgcac gattgaaagg tgcgcggttg gtcacttcgt cagaaccgaa tgaaggcgtc
    30901 cgactggacg aaggtctggt caaacaattg actggtggtg ataaagtcac ggctcggcac
    30961 ctttatggaa aagaattcga gttcgaacct gaattcaagt tgtggctggc aacgaaccac
    31021 aagcccatca tccgtgggac cgatgacggc atctggcgac ggttaaattt aattccattc
    31081 actgtccaaa tcccggatca caaaaaggat aaaaatctga aatttaaatt gcagacggag
    31141 ttgcaaggga tccttaaatg ggcaatcgat ggttgcctgt tgtggcagag agagggcttg
    31201 gagaaaccaa agtcggttgt tgcagcgagt caggattatc gaaacgaaat ggatcaaata
    31261 ggtacattta tcgaaacgtg ttgcgaaaca ggtccaggac taaaaatatc aggcggagaa
    31321 ttatacaaag tttatcgtga atgggcatca gataatggcg agcatacttt cactaacacg
    31381 aagtttggca gagagatttc aaagaaatat agcaaagaaa aagctggtgg atttatggtt
    31441 tataaaggaa tcacattaaa accaagaaaa tacgataacg ttagagaact ttttaaataa
    31501 atctggaggg ttctggaggg ttgagaacga aaccctccaa cccttagaaa cgttgatata
    31561 tcagtattta tattatattt ttctttcttt ctggagggtt ttaaaaaaat aataaagtat
    31621 taaagtaaaa aataaaaagt aaattatata aaaaagaata ggtttttggg tctgaccctc
    31681 caaactctcc accaaaatct tcctaaatgc tttgatacca acgattaaac agtctggagg
    31741 gttacattga aatcagaaca tcaaatacaa gacgagatca gaattgcctt atcaaaacat
    31801 ggttgcacga tttttcgatc caatgcggga caagtgacaa cgatcgaagg gcggcaattt
    31861 tacgggatgc caaaagggtt cccagatcta tgtggacatc gtaattctga tgggaaagca
    31921 atttatatag aagtaaaaaa tgaacgcggt aagttgcgtg aagatcaaaa aaggtttgct
    31981 gaatttttaa acggtcaacc tgtactatac ggtgttgcac gatcagtgga agaagcattg
    32041 aaaattgtgg aggaatcatc atgacaacag aagaagtgat tcaaatgcgt attcgaagcc
    32101 ttcagcgtga gattgacgat ctggaacgga caaaggcagt gatggtcaat gaaacggcga
    32161 ggaaggcaat cgatttgcac atagagaatt taagaaggga aatccat
//
LOCUS       DAFEKH010000031        31650 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.032, whole genome shotgun sequence.
ACCESSION   DAFEKH010000031
VERSION     DAFEKH010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31650
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.032"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            214..1500
                     /gene="efmA"
                     /locus_tag="LP386_001621"
     CDS             214..1500
                     /gene="efmA"
                     /locus_tag="LP386_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HBL1918859.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(1638..2237)
                     /locus_tag="LP386_001622"
     CDS             complement(1638..2237)
                     /locus_tag="LP386_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HBL1918860.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            2641..3762
                     /gene="mnmA"
                     /locus_tag="LP386_001623"
     CDS             2641..3762
                     /gene="mnmA"
                     /locus_tag="LP386_001623"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HBL1918861.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            4008..5429
                     /gene="arcD"
                     /locus_tag="LP386_001624"
     CDS             4008..5429
                     /gene="arcD"
                     /locus_tag="LP386_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HBL1918862.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            5443..6561
                     /locus_tag="LP386_001625"
     CDS             5443..6561
                     /locus_tag="LP386_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HBL1918863.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(6621..7913)
                     /locus_tag="LP386_001626"
     CDS             complement(6621..7913)
                     /locus_tag="LP386_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBL1918864.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            8045..8623
                     /locus_tag="LP386_001627"
     CDS             8045..8623
                     /locus_tag="LP386_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL1918865.1"
                     /translation="MRGNMEMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYL
                     SLRFLGYFTKEPTIDPEDSYFWMINNFIATLP"
     gene            8752..9129
                     /locus_tag="LP386_001628"
     CDS             8752..9129
                     /locus_tag="LP386_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HBL1918866.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            9062..11134
                     /locus_tag="LP386_001629"
     CDS             9062..11134
                     /locus_tag="LP386_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBL1918867.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(11345..12292)
                     /locus_tag="LP386_001630"
     CDS             complement(11345..12292)
                     /locus_tag="LP386_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL1918868.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            12538..13002
                     /locus_tag="LP386_001631"
     CDS             12538..13002
                     /locus_tag="LP386_001631"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBL1918869.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            complement(13064..14107)
                     /locus_tag="LP386_001632"
     CDS             complement(13064..14107)
                     /locus_tag="LP386_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HBL1918870.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(14484..15449)
                     /locus_tag="LP386_001633"
     CDS             complement(14484..15449)
                     /locus_tag="LP386_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HBL1918871.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            15683..16528
                     /locus_tag="LP386_001634"
     CDS             15683..16528
                     /locus_tag="LP386_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL1918872.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            16719..17906
                     /locus_tag="LP386_001635"
     CDS             16719..17906
                     /locus_tag="LP386_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBL1918873.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            17912..18268
                     /locus_tag="LP386_001636"
     CDS             17912..18268
                     /locus_tag="LP386_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HBL1918874.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            18270..18608
                     /locus_tag="LP386_001637"
     CDS             18270..18608
                     /locus_tag="LP386_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HBL1918875.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     misc_binding    18684..18940
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            19003..20037
                     /locus_tag="LP386_001638"
     CDS             19003..20037
                     /locus_tag="LP386_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1918876.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            20030..20716
                     /locus_tag="LP386_001639"
     CDS             20030..20716
                     /locus_tag="LP386_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1918877.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            20740..21588
                     /locus_tag="LP386_001640"
     CDS             20740..21588
                     /locus_tag="LP386_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBL1918878.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            21785..22558
                     /gene="sufC"
                     /locus_tag="LP386_001641"
     CDS             21785..22558
                     /gene="sufC"
                     /locus_tag="LP386_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HBL1918879.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            22571..23857
                     /gene="sufD"
                     /locus_tag="LP386_001642"
     CDS             22571..23857
                     /gene="sufD"
                     /locus_tag="LP386_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HBL1918880.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            23854..25089
                     /locus_tag="LP386_001643"
     CDS             23854..25089
                     /locus_tag="LP386_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBL1918881.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            25076..25546
                     /locus_tag="LP386_001644"
     CDS             25076..25546
                     /locus_tag="LP386_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HBL1918882.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            25551..26942
                     /gene="sufB"
                     /locus_tag="LP386_001645"
     CDS             25551..26942
                     /gene="sufB"
                     /locus_tag="LP386_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HBL1918883.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(27040..28182)
                     /locus_tag="LP386_001646"
     CDS             complement(27040..28182)
                     /locus_tag="LP386_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL1918884.1"
                     /translation="MATFFSYKLQNGEKYWGFETYLGKDPKTGKDIRTKRRRFKSKAE
                     AQTALNRLLVDFKEKQEFKINVTTFQELYELWIDNYRTRVKPSSVAVAQRFCKNHILP
                     AFGELRLDKISVSYCQKQVNEWHKTLKQYGFLRKTTAQIFKFGVAMEVCKDNPMSKTL
                     LPRKIEEEQPLKFYTKDQLQLFLQNTKENNSVKLYTFFRLLAYTGMRKSEALALQWED
                     IDYFNKTITIGKTIAQDEFNQVVLQVPKTKNSSRTIQLDDFTLKQLRIWQQEQMKIMI
                     LYGYNTNSPKQFLFTTNTNKLYYPQVVNDWLDWIYKKTPMEPQITPHGFRHTHCSLLF
                     ESGASIKEVQERLGHKDIKTTMNIYAHVTPQSVKKTGDRFAKFMGE"
     gene            complement(28233..29030)
                     /locus_tag="LP386_001647"
     CDS             complement(28233..29030)
                     /locus_tag="LP386_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1918885.1"
                     /translation="MKPNPSEAGKRIKQLRLSCGFTMEELGRKIDNSPRATISNWERG
                     TNLPNPQKLKLLSTITNSTIDWIKWGTLEEYITSYLIDIGYELYIKDFPEIPHKVFKD
                     IQERYSDTFSLDKDYELLNPIIKNIFTKYYSKDFEIYLNEILANNINPLIEEYANQRH
                     SISKELFFKRANSKLQDKIRNGDFKYGEKERMIDSLKQLLDEMDLAYKDISKYSSVED
                     FFYKITKNQFETEKFISDLSKKYNFPYEKNSIIAKFLTDNHDKFKNN"
     gene            29232..29531
                     /locus_tag="LP386_001648"
     CDS             29232..29531
                     /locus_tag="LP386_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1918886.1"
                     /translation="MEAIKLMISEEQEEMFLKQFYQIATKAIEKAQENAGMTREYLNQ
                     KEMAEYLNVSENFLKNAVRNEGLPVVELGARKFYSKKAVNEFMFARMKRGENIGR"
     gene            29796..30671
                     /locus_tag="LP386_001649"
     CDS             29796..30671
                     /locus_tag="LP386_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918887.1"
                     /translation="MNAIVILAEITYWYRPKKIFNDDGQLLGYQKKFLEDILQKSYKQ
                     LSKKTGLSERAIKDAIVYLEKKGIIKRVFRNIYYEKRAVTLSNVMYIVLNVHKLIEIT
                     FPTLDCEKKEYMPKIRQRGIEKKRYVSLKKGRGMYKFVYTYTKTTSQNISKTTLVMEE
                     EDINIKRIYSKISVLYDANNEDGRKLFQVYHYLRNANVDTEDIRKIIEYLSENTQYLI
                     AECIIKQHEACFFQRKTEEGLYDYVTYFLNGLQKRYKSQFLENVEPIDQFKKAFEIKE
                     LPEITMHNWLKGEES"
     gene            30668..30886
                     /locus_tag="LP386_001650"
     CDS             30668..30886
                     /locus_tag="LP386_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918888.1"
                     /translation="MIKNRLIDQMWCLDQNTDTLELIESICFNTVVLDLRAENDNCVT
                     HIIINQKMAQQLSESLRKWAEGENYESN"
     gene            30873..>31650
                     /locus_tag="LP386_001651"
     CDS             30873..>31650
                     /locus_tag="LP386_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="HBL1918889.1"
                     /translation="MKAIKEKIVSRKINWLALSVLVLMISVVFTSNIVEASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSVINTIVVGLMILSLMFVGYKMITGKGTIDLRSVGMNIVMSVALI
                     LLMPTMISSGIQFAKIFYNDATTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNKLTRKNFQQTDLTQVLTDKVIDKLEKENPAADNLRYE"
BASE COUNT        10420 a         5606 c         6630 g         8994 t
ORIGIN      
        1 ttgtaaggac gacgcaaatt agttgtcttt tttattttta aatttaacac atgttgttat
       61 ttttaatatt ttgctgattt attgtttcta agtaaagaaa tttaaattga aacgattgtt
      121 atttagggaa aaaggtattt tttgaaaaaa gaatcccgta taatgattgt tgtgcaaacg
      181 ctatacaaaa tgaaaaagaa aagagggatg tttatggaaa atgaacagtc ggtcgtttta
      241 acgaattgga agagaaatta tttgttcttt ttatcgggac agtttttgtc aggaatcact
      301 agtatggtcg tccaatatgc gatcatctgg tatttgacaa gagaaaccgg ttcggcgaca
      361 attttgagtt ttgctacttt actaggaatg attcccatgg ttttactaag cccatttgta
      421 ggaccgctag tggatcgctg ggataaaaaa gctcttttga ttgtcacgga tattattgta
      481 gcgattttcg cgcttatttt agcagtagtc ggaacgattt cagaatcctt cccgatttgg
      541 ctagtttttg tgtctttgtt tatgcgttcg gtcgcacaaa cattccaaat gccaacgatc
      601 cagtcgatta tgccgacaat cgttccatct tctcacataa caaggacgaa tggacagtta
      661 ggaatggtcc aatcagcgaa tttcatcatt gcgccagctc taggtgcggc tttgttttca
      721 gtcgttcctg tcaattacct tattttatta gatgtattgg gggcagtttt tggtgtcggc
      781 ttattgattt ttgtgaagat cccaaaagtt tctcctgaaa tattggaagt tccgcttact
      841 atttttaaag atgcaaaatt tgggctgcag caattgatgg ataataaagg gttatggtac
      901 ataacgatca atggtgcatt tgtgatgctg ttgttcatgc cagcaatcag tctgtatcca
      961 ttgatgacgc tagattactt tggtggttcc gttggacagg cgggagcagt ggaagtagtc
     1021 tacgcagtcg gaatgctctt aggcggtgca ctgatcagtt ttataggaac atggaaagac
     1081 cgaatgaaac ctattattat agcctacatc attatgggcc tgacgatcgg tgcaagcgga
     1141 ttggttccaa acgatagtca agggttcttg tactttctta tcttgaatgc aggagcaggt
     1201 tgtgcaacgc catatttcaa tacactgctg atggcaatga tccagcagag ttatgaatcg
     1261 aatgttttag gtcgtgtctt agggaacttc aactctttga tgaacctggc aggtccaatt
     1321 ggattattat ttgcaggacc attagctgat cgtttagggg tagaaaaaat gttcttgttt
     1381 tccggaatcg ggattttatt atgcggaatc gttttatttt taacgtcagc tgcccgaaat
     1441 tatgataaag aattacagaa aaaactggta aaagaacacc atgagcaaaa agacgaatag
     1501 tatggaatgg agttgtgaca gaagtcttgt tacaactcca tttctgatcc taatgttcct
     1561 gtggcaataa gcctactcaa atgaaaaata tgagtaatta tctttatttg tttaatactt
     1621 gatatagggc agttttttca cgacctatcg tacttcctct ttgcttcata gatttctttg
     1681 atttgttgct cagataacgg agtgccaaat ggtagttttt cctttaagag ttctctttcc
     1741 ggtgcgtcta cgcctacatt gacatcgttc tcgataggta cgctgtaatg atggatatgt
     1801 ccatgaagat tgcggatagt gtcgttaggc ccgagcaaca tcggataatg agtcaagtaa
     1861 tattgttgat ggtcgaattt aacgatggca cctacatcat aaaaataaaa tttgggactt
     1921 ccgtcagtaa gcctaggatc atttttttct aaataacgga aaaaagcgcg actgtcatgg
     1981 ttccctttga tcaagtggat tgttccttgc agttgagtga ccagttccaa aatttctgca
     2041 tttgcttttt catattgcgg atgcatagca aggtcgccta gatgataaac atggtcggtt
     2101 tcttttatta ctgcattcca gctagtgatc aactgttggt tcatttcatc cacatttgca
     2161 aagagccgcg gagcaaagtc gttttttcct aataagcgtt catggaaaaa gtgcatatca
     2221 ctgataaagt aattcatgta tcttttgcct cccttttttc ttagagtaaa caaaatcact
     2281 tatctgagca actcataaca tctaaaaaga aaaggttgta aatgagacgt gcagctttaa
     2341 gcgataagaa gcaattttga aaaatagttt ttcacaattt ataaaattat tccttattgc
     2401 cgaaaggctg gcccttttta tgagtatgcc aattttttat atcgaatgct caaaagatga
     2461 gtgatttttt ggttgactat catgtttgtg tactgaatag gtccagtaga acagtatttt
     2521 tacgacttga taattaaggg atgaaatttt cagaaatatg acgtataatg taaaatactg
     2581 aaaagttgcg accttcaact cgtagatgtt tcagaatcta attgaaatga tggtgatatc
     2641 atgacagaca acagcaaaac acgcgttgtc gtagggatga gcggcggtgt cgactcatct
     2701 gtaacagcac ttttgttaaa ggaacaagga tacgacgtga tcggaatatt catgaaaaat
     2761 tgggatgaca cggacgaaaa cggtgtatgc acggccacgg aagattataa ggatgtagcg
     2821 aaagtagctg ctcaaatcgg gattccttat tactctgtga attttgaaaa agaatattgg
     2881 gatcgtgtat ttgaatattt cctagccgaa taccgcgcag gacgtacacc taacccagac
     2941 gtgatgtgca acaaagaaat caaattcaaa gcattcttgg attatgcaat ggatcttggc
     3001 gccgattatg tagctactgg acattatgcg caagtcactc gcgatgaaaa cggcgtggtc
     3061 cacatgcttc gtggagtaga caataataaa gatcaaactt acttccttag ccaattatca
     3121 caagaacagc tttcaaaaac gatgttccct ctaggcggca tggaaaaatc agaagtacgg
     3181 gcaattgctg aacgcgcagg ccttgcgact gctaagaaaa aagattcaac gggaatctgc
     3241 tttattggtg aaaagaactt caaacaattt ttgagcaact atctgccagc aaaaaaagga
     3301 aatatggtca ctcttgatgg tgaagtcaaa ggacaacatg ctggcttgat gtattatacg
     3361 attggtcaac gtcaaggact agggatcggt ggcggaggag attcgcaaga accctggttt
     3421 gttgtaggaa aagatctagc gacaaacaca ttatatgtgg ggcaagggtt ccatcatcct
     3481 gcattgtatg ccacaagctt ggatgcaagt gaaatccact ttacgacgaa tgaaccaatg
     3541 ccaaaagaat tcaagtgtac agcgaaattc cgttatcgtc agcaagacgt tcctgtgaca
     3601 gttcgcttat tggatgataa tcgtgcagaa gtcgtattcg acgaacctgt acgtgcaatc
     3661 actcctggac aagcagttgt attttatgat ggaatggaat gtctgggtgg tggtttgatc
     3721 gaccacgcat atcaagaaac aaaagtttta caatacgttt aagcgatatt aaatgaatca
     3781 aaacagctat ggctaacaaa agaaacacct tttcttttgg atagcatagc tgtttttttg
     3841 caataaaatt aatttttatt cattttatac ttgaaatact tgtgtaaaaa gttcgtaata
     3901 tccaataata tgaataaagt tgctttttgt taagcaagag cagttgcaaa atagaaggga
     3961 atcttttgca agtgatttgt tcaattttat aagtgagggt gatggaaatg gaaaagaaat
     4021 cgacgggtat tagcaaatgg ggactggttg ctctggttgt cagttcgtca atcggaagcg
     4081 gtgtgtttgg gatcacaagt gatctggcta gttctgcagc tccagggcca gcgatccttt
     4141 catggataat cgttgggatt ggtattttag ctttggtatt atcgctgaat catttaggag
     4201 aaaagcgtcc agatctagat ggtggtattt tcggttacgc ggaagcttca tttggtaaat
     4261 taggtggctt catcagtggt tggggttact ggttgtctgc gtggctggga aatgttgctt
     4321 ttgcaacgat gctgatgagc gccatgggag aatttttccc gatattcaaa ggtggacaaa
     4381 atgttccttc tattttattt gcaagtattt ttatttgggg tctgacttta ttagtaaaca
     4441 atggagttga aggagcgagc gtcatcaata caatcgtgac gatctgtaaa ttagtgccat
     4501 tattcctatt tttaatattt gtatttatcg catttaaagt gaatatattc actgctgatt
     4561 tttggggtaa cgtatctgat aatctagtga atggaacagg gcagcaagga acgatctggt
     4621 tgcagattaa aggttgtttg atggttatga tgtgggtctt tgtagggatc gaaggcgcaa
     4681 gtgttttagc caaccgcgcg aagaaacgtt cagaagccca gcaagcatcg atcattggtc
     4741 tgctttgttt attgtttatc tatatccttg cttcgatctt gccatacggc gtcttatctc
     4801 aagaagagtt agcaactatt tcacaacctg ctatggcaaa tattttaaaa ggaatcgtgg
     4861 gaaattgggg agcagcgctg atcaatatcg gcttgattat ttcgatcatt ggttcttggt
     4921 tgtcttggac gatgctccca gcagaaacaa cgatgttgat ggctcgagac ggtctgttgc
     4981 cgaaaggttg gggaaaaacg aataaaaaaa atgccccaac ttattcgtta gttgttactg
     5041 caatcttgac taatctattc ttattgactt tcttagttac tgattatgcc tatcaatttg
     5101 cctattcttt atgtacagcg gcaattttga tttgttatct acttgtcggg atctatcaag
     5161 tccagttttc tttaaaagaa ggaatcaaaa aacaagtagt gatcggtggg attgctgtag
     5221 tttttgaatt gatgggcatc attttagcag gattttctta tgtcctttta tgtagtattg
     5281 cctatcttcc tggtttttgc ttctactgga tcgcttgtcg tgaaaccaaa catcaaatta
     5341 cgggaaaaga aaaagtaatg attgggctga tttgtgtggc cgcactgctt tcaatcgggt
     5401 tgcttgctgt aggctggatc aagatataag ggggaaagaa acatgaaaat cgcaaatttc
     5461 ggtgtagaag aatggctaaa taaatgggaa aagaaagcgg tatatgatat tgcacaaagc
     5521 tcgatcgaag cattgacatt agacgaactc gttggcttag atgggactag cgtaagtaaa
     5581 tttttcgaaa aacgcaaaaa cgaaccattg gactatggct ggatcgaagg atcagatgtt
     5641 ttcaaacaag aagtcgcttc tctttatcaa accgtcgatc cggaaaacat cttacaaacg
     5701 aatggagcga ctggtgctaa tcttttagct ctatacgcgt tagtggaagc aggagaccat
     5761 gttgtttcga tgcttcctac ttatcagcaa ttatatgaca tccccaaatc tttaggtgcc
     5821 gctgttgact ttgttcattt gaaggaagaa gaagattggc agtttgattt agaacagcta
     5881 gaagccttag tcaaacctga aacaaaaatc atctgtttga atagtgcaaa caatcctaca
     5941 ggcacattgc tagatcggaa aactttagaa aaaatcgcag aaattgctcg tacagtagat
     6001 gcatatgtat tgatagatga agtatatgcg cctttaacgg ataaaggtga attcttgtcg
     6061 atcgtagatg tctatgaaaa aggtatagca accaattccc tatccaaaac ctactccatt
     6121 ccaggtattc gtattggctg gacagctact ggacctgagt tggcagaagt ttttcgaaag
     6181 tatcgagact acacgatgat ttgcggcgga gtcctgtcag atgatcttgc tgtacatgca
     6241 ttgaagaata aagaaaaaat attggcgcga aacaaaaaga tcattacaga gaaccttgtg
     6301 attttaaaac aatgggtagc caatgaaccg aaagttgaac ttgtcgctcc caattacgtc
     6361 tctacttctt tcattaaatt agccatcgaa gaagatgacc agacattttg tatcaattta
     6421 ttagaagaaa caggagtact attagtacca ggaagtgcct ttgatttacc gaagcatgcc
     6481 cgactaggtt actgttgtaa aaaagaaacc ttggaaaagg gattattcct cttatctgag
     6541 ttcttgaaaa aacaggccta aacaaaaaca ctgcaaggac agtctgtgac aactgttcaa
     6601 gcagtgtttt tcatttacgc ttattgtcta tgagaaggag agtgccctga agctatggag
     6661 actcctgaag ctttttcttc tgcagtttct tgctgatgga tctcttgtgt attgtgtcgt
     6721 acaagcaaga agttgaccaa aacaagaaga gaagtcgaaa gaaagacgcc gcgataacca
     6781 aatgcactgg aaacactgga gccgatcata ggccctacta cgttaccagt tgcttggaaa
     6841 gattggttat aactgaagat ccgtccagca gcttgatgag gcgaatattt tgtgatcaat
     6901 gcttggacag cagggagcag acaagcatca gagataccaa tcaaaaaacg taaggcagct
     6961 aattgccaaa cattcgtgac gaatgccatt gggatataaa ccagaatcgc aaaacccaaa
     7021 ccaatcgcaa gtattctttc actcccaatc ttgtcaccta agcgaccaaa tcttggagcg
     7081 gctatcaaag tggcaatccc aggtatcgaa gcaatgattc cgctgatcaa cgtaacattc
     7141 ccatgtccat gcagcaattg gcgaatgtac agactgatga ttggactaat ggaattgttg
     7201 gatgcttgga tgatcatcgt tgtgacgaac ataccgatga cgacgtgtgg atatttcaag
     7261 tctttgaaaa tctgtttggc agaaaccatg ttttcttttt tcactgggac aaatttttca
     7321 tggacgaaaa acagactcaa caagaagacg aaaaataaga tgatccctgt aatgaaaaag
     7381 gtagggcgat agccaaacgc tgaagcagag atcccgccaa gaagcggtcc aagtaatgtt
     7441 cctgtaacag aaccagttgc taaggttcca agaacttgac cacttttttc ttttggcgtc
     7501 ccagttgcga caagggcagt ggcattactg atataaccag aaaaaatccc ttgaagcaga
     7561 cgcaatgcga ctaattgata cacactagtc acgcaaccca tcaaagaaat gacgattgcc
     7621 attcctaatg aagcacgcaa cagcatcaat tttcttcctt tttggtcggc taattttccc
     7681 caccaaggag agataagcgt agtcaccaag aaagtagatg aaaaagtcaa tccgctccaa
     7741 aagttcaatt gtgacgtact ataattacct aacgtatcta tgtaaagtga cataaaaggc
     7801 atgactaaac taaatccgat accagccata aatgttccaa accataagac aaacaagttt
     7861 tgttcccaag tttctctttt cctaaataat ttttccttta ttcttgcagc caattagact
     7921 ccttctttct gaaaattttc atctacagct ctttattata aactacaata tgtagtttat
     7981 caatgaaagt ctcttttttc tctttctttt tcgtggtaaa ctgaaagagt gaaggattta
     8041 ttttatgaga ggaaacatgg aaatgaaaaa aagaaatctg tctcaagaga aaatcatcga
     8101 ctgctttcga gaactagcag aagagatgga tgttcagcaa ataacctttc agcatttagc
     8161 caaacgcttg gatatcaagg ctccctcgct gtataaccat ttcaaaaata ttcgtgatgt
     8221 caaaacagcg ctaacagcga aacttctgca ggaacttaat gaccagctgc gacgggctct
     8281 tgtgggaaaa agtggtcagg aagcactgca gatctatgca gaaacttatc gatcctttgc
     8341 tttttcaaat caagcagtgt atgagttact gatcagtgta ccgcatacca atgaagctgt
     8401 tttattagat ggaatccatg aaacgaatca gatcattttg cagatatttg aggcttttca
     8461 attaacgaaa gaagaaaaag ttcatcgaag cagggaactt cgtagtatga tccacggtta
     8521 tctttcctta cgttttttag gatactttac aaaagaacca acaatcgatc cagaagacag
     8581 ctatttttgg atgatcaata actttatcgc tactttgcct taaacaatca gattcatttg
     8641 taacaatttt aagatgttca ttaaatgacc cttttataag agaaaattct tgcaactttc
     8701 ttgaaaagtg actaagatga gtctagaaaa gctgaaagaa ggagcacgag tatgtatcaa
     8761 gtaattacca tgttcgggga caatgagcct tggtggtttt ttgaagactg ggaagaagat
     8821 attgaagaag aagaaacatt cgagtctttc gaagaagcac gacaagcgta cgaaaaacaa
     8881 tggaacgaaa tccatcaaaa ttatgaatat atcaatgcaa aaagtaactt tctcagcgcc
     8941 ttttggaatg acggagatga gcgctggtgt gaagagtgtg acgatgattt acagcaatac
     9001 aagggacttg cgttgttgaa aaatcatcag cccatcacag tagaaagcag aaaggaattt
     9061 tatgaaacaa ctaattctag cggaaaaacc aagcgttgcg aaagacctaa gcaaggtgct
     9121 tggtgctaat caaaagcaca aaaattatta tgaaggaccc aaggtgatcg ttacttgggc
     9181 ccttggtcat ttattaggat tgaaaatgcc ggaagatctg aataaggaat ggcagagctg
     9241 gcaaatggac acgttgccaa tgatccctaa aaaactagga atcaaaccac ttcctaaaac
     9301 aggacatcaa ttaaaagcaa tcaagcagct ggctcagcga aaagatgtct cagaagcagt
     9361 cattgcgaca gatgccggaa gagaagggga acttgttgct cgctggatct tagagtatgt
     9421 gcatttcaat aaaccagtga agcggttatg gatctcttct caaacagata aagcaatcaa
     9481 aactggattc aagcaactaa gacctgcgaa agaatatgat gcattgtatg aatctgctct
     9541 tgcccgggca aaagcggact ggctggtagg attgaatgtg accagagcct taactgtgaa
     9601 gtacgcggat aatttatcag caggccgtgt gcagacaccg acactagcat tagtgagaga
     9661 ccaagaaaag aaaatcgagc agttccgtcc acaaacgtat ttcacgatca cgttgcaagc
     9721 tggaaaagaa caagccaaaa tgcttcaaaa aaatcaattt gctttaaaaa cacaagaaga
     9781 agcacaaaaa cttgttcaat tgatcagtac aagcaaagga actgtcacag aagtccaaga
     9841 aaaattaaaa acggaatctg cgccattgcc ttatgattta acagagatcc aaagagaagc
     9901 caatcaacgc tatggctatt ctgcaaagaa aacattaagt cttgtacaaa gtttgtatga
     9961 gacccataag atcgttactt atccgcgtac agacagcaaa tatctgacaa atgacatgaa
    10021 aagtacgatg aaagaacgat tgcaagcagt cagcgacttt gctcctgagg tcaagcagta
    10081 tttgaaaaac ggagccatcg tccaacagac aaaagtattc caagacagta aagtgaccga
    10141 tcaccatgca cttttgccaa ctgaaaacag agcacgttat gaaaaattaa gtaatgaaga
    10201 gcgaaaaatc tatcaaatga ttgtctctcg ttttttagga ctgtttgctc aaccccataa
    10261 agtcagccaa acaaaagtta cggttgaatt tggtaaagaa cgattcattt ttcggcaaaa
    10321 tcgtgtcgtc caagcaggat ggaaaggcga aactgaaact gagacggaaa cagtcaaatg
    10381 ggaaaaagga atgagaatca atcccgattt cgccatcaaa aaagaactat ctgcaccgcc
    10441 taaaccattg tcagaagcaa gcttgcttgg tcaaatggaa aaatacagtc tgggaacccc
    10501 agctacgcgt gcagagatta tcgagaaact aatcaaatct gaactgatgg aacgtacccc
    10561 tcaaggactg caagtatctc ctaaaggtaa gcaattatta gtattggtaa atccctcttt
    10621 agtaacacca gatttgacag aaagctggga aaaagacctt gaagctattg ctgcaggaaa
    10681 gaaacaagca ggaaccttct tgaatggaat cgaaaaagaa acaaaacgct tggtgaatga
    10741 gatcaaatca agcaaacaag aatatcaaga tttctcgatt acccaaaaga aatgcccaga
    10801 atgtggggcc aatctgcgcg agaaaaacac acgtgacggc aaaatctatg tctgcaccaa
    10861 ttcagattgc aactaccgca gaagaaaaga tccaaaagtc tctaatcatc gatgcccgca
    10921 atgtcaccgg aaaatggaaa tcatcgaagg taaaaacggt gcttatttcc gttgtaaata
    10981 cgatggaacg acagaaaaat tgcttgataa aaaagagcag aagaagaaaa tgaccaaaca
    11041 tgaagaacga cgcttgctga aaaaatatgc acaagcagaa gaaccagaag aaagcccatt
    11101 agcagcagca ctaaaagcag caatgaagaa gtaataagat atgaaagagg ttgtgataga
    11161 agtggtcagc ttcaagaaat aagaaggaat ttacgaaaat tgcttctcaa atttttgtga
    11221 aatttcggct tatttccgaa gaagctactt ctggaacacc atttattcgg aaaaaaggac
    11281 tgtgacaaga cttttgtcac agtccttttt catttaaaaa aatgtttact tcatttgacg
    11341 tatattattg gtgaggcttc aattcatttg gcttcacttt ttctgtttct cttatgatat
    11401 aaacaggacg ctgtttcgtt tctaagaaga ttttcccaat atatttcccg atgattccaa
    11461 gacataacaa ttggattcca ccaatgaaca ggaagatcga gaccatggaa ggccatcctg
    11521 atgtaggatc accaaacaac aatgcccgca aaataatgaa caaaattgca ataccagaac
    11581 cgacacaaga caaagcgccg ataaatgaag caatcgttaa cggtgcatcc gagaagttca
    11641 cgataccatc aatcgagtag ttgaataatt tccagaagga ccaagatgtt tcgccagcca
    11701 cacgttcgcg gttttcataa gaaatatatt ctgttttaaa tccgacccag ctaaataatc
    11761 cttttgaaaa tcggttgtat tctgttaatt ctaggacggc atccaccatt tgacgagtca
    11821 tcaagcggaa atcacgagcg ccatcgacca tttctgtatc gctgatttta ttgatcaact
    11881 ggtagaattt tttcgcaaag aaactgcgta tcgcaggctc gccttcacga gtcgaacgcc
    11941 gggtgccgac acaatcgata tcagaagtag tgatccggtt gatcatctca ggaagcagtt
    12001 cgggcggatc ttgcagatca acatccatca cggtcactaa atctcctgta gaagcttgca
    12061 atccagcgta cagagccgct tctttcccaa aatttctgga aaatgagaca aagcggacat
    12121 aaggataagc tgaggctagc ttcttgattg ctgctaacgt accgtctttt gatccgtcgt
    12181 caataaacaa atattcgaac tcatgggcac ctttgaattt ttcaacctca tcaaaaaaaa
    12241 gaggaacagt tttttcttca ttaaaacatg ggacaacaat tgatactttc atcgtttcta
    12301 tcctttcaat cgtatgttta tatatggttt acattcaaaa tttaataaac cttaaataac
    12361 acctttaaaa tttgatttta cgtaaaagaa caggtattct ttttgtaaac taacgtattt
    12421 agtttaccat gtttcctcgg tttatcaaac ttttaagaac aatttttatt agttggcaag
    12481 tagttttgga tagagaaaaa ggaggaagtt ccagtctatt gactaggagc aaacaaaatg
    12541 aaaatacaca cacctatcgg ctttttatgg ttagatgcag atgaatccgg attgactgct
    12601 gtatcttttc agccaatttc agaaagcgaa tcagcgaatc agcgaatttt aacgcgcaca
    12661 caagaacagt ttgaagaata ttttgcggga aaaagaaaag aatttgatgt tcctttatct
    12721 ataaagagag gtacgccttt tcagcaaaat gtctggaaag ctttgtcgac cattccttat
    12781 ggagaaatcc gaacgtataa agaagtagcc gttgctgttg atagtccgaa agctgtgcga
    12841 gcgattgggc aggcaaatcg aaccaatcca ttgccaatcg ttattccttg tcatcgagtg
    12901 atcgggcaaa atggaaaact gacaggatat atgggaaacg caatagatgg ggttgaaatc
    12961 aaacgccaat tgttgttgtt agaaggatat ctgcaaaatt aaaaacagtt gtgattcgga
    13021 cattgttcca tgcgagaatc acaactgttt tttcatgttc attctaaact ttgatcagcc
    13081 aaataaatag taaagccatc actgtttgga gaagcccgac agctaatcca taagataaga
    13141 agcgtgtacc ttctttcatg aattttgcaa agtctaaacg cagaccaatt gccgctaaag
    13201 cagtgatctc aaaccagctg ctgataaaat gtgccgattg gtcaataact acaggtaaag
    13261 aaaacaagct gttgaccaaa caaaagatca caaaccctaa tacataccaa ggaagcggta
    13321 attttcgttt tttctgcgta tcagttggcg tttcaaacag agctggttgt ttcttgtgca
    13381 tgaatttttc aaacagatag acaacaacaa cgagcatcat aatacgtaga atcttaaata
    13441 gcatggcgaa ttcgacaaca gaattgtcaa gtaagcttgc cccagcgact acttgaccaa
    13501 cagattggag tgtaccaccc aaaagtgcac ttttttcaat gagatttcca ccaaacaact
    13561 gtaatccaag aaaagggaga gtcaacatca tcacagtacc cagtagattg actagtgtga
    13621 tgatctgtcc tttttcttcc tctttcgcat ggatggaagg ggcgattgaa gcaatagcag
    13681 aagaaccaca aacagcgttt cctccagcca tcatcaaaga agaagtatcg ctgaattgca
    13741 gttttttacc aatcaagtaa gcaccgatga tagtgactga catttgcagt aacacaaaaa
    13801 caattccttt tacaccaatt tgagcaatcg tttgagctgt gacagttgca cctagtaaaa
    13861 aaacagagaa ttctaatagt ttgctttcag caaattttgt gccgattgct agaacaggct
    13921 gtttaaaaaa agtatttcct aataaaatac ccaataaaat agcaatagtc gctccaccta
    13981 actgtggcag ataaatagca agaagcctgc tgaaggcagc gatggcaaaa gaaagcagta
    14041 aaccgggtaa gatttcgcgg accgctgaat cctttacaga ttttattgga tgtgacaatg
    14101 atttcatttg atcggttcct ttcgtcaata aatactaaaa gcatactcga acatagtagc
    14161 actaaaccag tattttgaca aaagaacaag aggtcgtgac aaaagtcttg tacgacctct
    14221 tgtttcgaat aaacggtgtt ccagaagtag cttctacgga aataagccga aatttcacaa
    14281 aaatttgaga agcaattttc gtaaattcct tcttatttct tgaagctgac cacttctttt
    14341 acgacctctt ggtaaacggt gttcaaaagc ttgcatctgc ggtaataagc ccaaccagta
    14401 caaaaacatg aacagctgtt tttgtttggc cgttcttatt acttgatgca gaacagcttt
    14461 ttcacaacct attgaatcga ttattaagcg atttttttag aaacaaattt tccatgtttg
    14521 ctatgttctt taattaagaa acgtacgtaa tgagcaagaa cgtagaagac aactacactt
    14581 gcaaacagac attccgcaac ttttaagaaa tccaatacgc tactatagat acctaaactg
    14641 ttgaagtaat gaacagtagt aaatatagct gttgcagaga taacaagcgg gaatgtaaag
    14701 gctgcatagc ttggataaaa acgaagcttg aacaaacgtg gaagcataga cagcacaacg
    14761 aaatacaata cttgagataa agcgaacaat gctacgacaa gataaaaatt aggttcagca
    14821 aagtttttaa gataacctgt taggcaaaga gaaccaggtg ctgcaacgat cgtaatcagc
    14881 ggacgtgtcg gatgagccat atttcttacg aaaaagacac gtttgatgat gatcggcaat
    14941 aagaacgcat agcagatcaa tgaaatccaa aagaaaattt ttccaataag tgggaagaag
    15001 ttcccggcag ttacagtgat gaccccaaat ccaacgtaaa tgataaacca gcttggataa
    15061 attgcttcaa ttgaaagatc agctttgata acatggtgat aattgaaata aaagacaagg
    15121 atcacttgga agataacagc gcacagccaa atgaatttga caattggtgc aatactttca
    15181 tatgaaacaa aataagtaca aataaccatg agtgacatcg taaaagttgg tgaaacggag
    15241 gcgatgattg gatcatgcaa cgtttgtttc gtgtgttcga ataagataaa caatttaaca
    15301 aaaatgaata tcataagaat catagagata ccgccagtta gattgcctaa agcaacatgg
    15361 tgatagtctt taaacagatt tccaagggaa gctaacccaa ggatcaaccc gcagatcggg
    15421 atcggaataa ttttcaaaaa gttcttcata tataatattc tcctttttat ttaatagatt
    15481 ttagtaccaa gatgaacgaa tacattgtaa aatgaatagg aatgtatgat tacgagcaag
    15541 cagacagctg attgtcttca tctaagttac tagttggatc agcaactgtt ttgttgtaca
    15601 tttctattat agatggtttt ttgtatattt aaatcaaata gtttttatag taattatcat
    15661 aaaaagttat ggaagtggtg ccatgtttaa gttattaacg acttttcgag cagtatatga
    15721 aacaagaaat ttttccagag cagcagaagt actgttttta tctcaaccag cagtctcgaa
    15781 tcaaatcaaa cagttggagc gggaattgaa tatcgatctt tttcaacgta acggaagaaa
    15841 agagatgctt ccaactaagc aagccgactt attatatgaa cggacactgg ttttgttaga
    15901 agaatgggaa gaaactcagc aaaaattgct caatgaacaa aatgaagaag aagtatgtcg
    15961 gatcgttgct tcccacacct ttgctgtcta tcttttgcct cagttgatga aacatctgat
    16021 caaaaggttt cctaaagtgc attttgagat cgaaatcacg aattctcatg aatcattaga
    16081 acaagtagcg aaacatgaat ccgattttgg ttttatcgaa aagccattag agacttccgg
    16141 cgtacaaaga tactctttga tggaagacca gctagtcatc gctggggacc caaaaagcaa
    16201 attgtggctt gtaagagaag caaactctgg tgtttttcat tacacgcagc gttattttga
    16261 agagatgaat atccaagata agaagatgat cgtgaaaagt aacgatgtaa ttgttgcgtt
    16321 gctgaaggaa ggaatcggtc gctcgatttt gtctaagcgc tctgttccag aaaatgtgcc
    16381 aatgactccg ttgaatttcc atcgatattt ttatttcatc caacgaacca atctggtttc
    16441 tgatcagctg ctagagattg ccgaagagat ccttcgatac aatgaaagca cagaaacttc
    16501 tcacagcgag gagaatctca gctggtagat aattgcatgt atcaaaaaaa gttctatgat
    16561 acactaaaga taagcagtag gcttttgtac tgcatttgct caagcaactg cacaaacgga
    16621 aagttaattt ttcccaaatg tctatggaaa gactttccat tatctaactg gaccgctata
    16681 ataatcagca gtatggtttt taagaaaagg gatgaaacat ggaaaaaaaa ttaaaagctt
    16741 cgaacgataa tcgtattgat tatggcgtga ttttaccagt ctttctgtta tgtttgattg
    16801 gtctgctctc attatatgta gcacttagcc atgatccgaa caatccagca gtcttgaaag
    16861 gcgtagggat gcaagttgtc tggtatttag ttggagcggc agcaatcgtt gtcatcatgc
    16921 atttgaattc caaatggatc tggaaactga ctccttacct ttatggtttg gggttagtgg
    16981 taatgggact cttgctcaaa ttctatgatc agaatttagc tgcttcaaca gggtctaaaa
    17041 actggtttcg attcggtgcg tttactttcc agccagcaga gttgatgaag attgcgtaca
    17101 tcttgatgat ggcactgatc gtaactaaac ataatacgca agtaaaagaa cggacgatga
    17161 aatcggactt ttggctgatt gggaagctct tgatcgtgac aataccggtt ttagcattga
    17221 tcatggccca agatgacttt ggaacgatgc ttgtctttct tgcgatcttt ggcgggattt
    17281 tcctgatgtc tggaatctct tggcgcatca tcgcacctgt agtaatcttg gcagtagtcg
    17341 ttggagcagg aacgatcttc ttggttacga ctgaaggcgg aagagacttg ctttataaag
    17401 ttggattcaa atcttatcag tttgcacgta ttgattcatg gctggaccct ttccatgata
    17461 cgtcaggaat gagttatcag ccggcccaag gacttttggc aattggtacc ggtggcttgt
    17521 ttggtaaagg attcaacgta agcaatatct atgtgcctgt tcgtgagtcc gatatgattt
    17581 ttaccgttat cggtgaaaac ttcggcttta tcggtggtgc attcgtcatt ttcttgtatt
    17641 ttattttaat ctatcgtatg attcgggtgt gtttcgatac gaataatgaa ttttacgcct
    17701 atatcgcaag cggtttgatc atgatgctgc tgttccatgt ctttgagaat attggagcaa
    17761 atatcggatt acttccttta acagggatcc cattgccttt cattagtcag ggaggatcct
    17821 cgattttagg gaacatgatc ggtatcgggt tgatattatc gatgagatac caaaatgaag
    17881 cacctgcaag atcttcaagg aggtaagaaa attgtacacc ttttactggt acccgaaatg
    17941 ttcaacatgc aaaaaagcca aagcgtggtt agaccagcat ggcgttagtt atcaaaccgt
    18001 tgatatgatc aaagaagtac cgaaggcctc aacgattgag acttggctag aaacgagtca
    18061 agtaccaatc cgtcgcctgt tcaacacaag cgggatgaaa tatcgggaac ttggactgaa
    18121 agatcaagta ggcgagttta cggcttcaaa agcgagccaa gtcttatcga cagatggtat
    18181 gctgatcaag cgaccactga tcttacgaga ggaccagctt gttgcaattg gattcaatga
    18241 aaaaatttat gaaggagaac tgatataaaa tggcaggcaa gcatttgaag aaaaaggaca
    18301 acctttggat cttatttaat ggaaaagaat actgtgttgg tttgacaaat gaagcgcaag
    18361 aagaacttgg agacatcacg tttgccaatc tgccaaaagc aggacaatcg ctaaaaaaag
    18421 atgaacctct gatcgaagtt gaagcggaaa aagcggtcaa tgaatttgcc agcccgctaa
    18481 cgggtacagt ttcttctgtt aatgataaaa tcggtgaaga tatcaatatc ttgaatgatt
    18541 cagatgaaat gaatgcgtgg atcttaagtt tcaaagatgt tgatccaaaa gaatttgacg
    18601 aattataaaa tcagaaaatc acttgaaaaa agttgacact gattcttcca gttgctataa
    18661 tcataagcaa tcctatatga aacgagaaag ctttgaaaag aagagtacat gtcacggacg
    18721 tttgaagaga gccctgtttg ctgaaaatgg gtaacgaaaa tgagatggaa gatggtctta
    18781 gagcagagta agcgagcgta agcaaactta ctacgggagt gcccgttaca gcgcgacagt
    18841 atacggaaag aagctaagtc caagtactgg aagaggctgt tattgcgaag taacggtaaa
    18901 tcaaggtggt aacacggaag ttcaagcttt cgtccttttg cttaaggcaa gagggcgaag
    18961 gcttttttgt ttgaaaaatt ataagagaaa gatgtgaatg gcatgtcatt aatccaacta
    19021 acgaatgtca aaaagacatt caatgggaaa aacggaaaca tccaagccgt caatgacgtt
    19081 tcactaaacg ttgaaaaagg ggatatttat ggaatcgtcg gctattctgg cgcaggaaaa
    19141 agtacattag tccgtctcct gaatggactt gagcttccca cgagcggcga agtgatcgta
    19201 aacgatcaag atattacaaa attaaaaaac aaagaattac gtacattccg aaagaaaatc
    19261 ggtatgatct tccagcattt caacctgtta tggtcaagaa ctgtacttga aaatatccag
    19321 ctgccgctgg aattagctgg cgtaccaaag agcaaacgta aagaacgggc agaagaactg
    19381 ttgcgtttag tcgggttaga aggacgcgga caagcatatc cttcacaact ttccggcgga
    19441 cagaaacaac gcgtcggtat cgcacgagca ttggcaaatg atcctgagat cctgctttgt
    19501 gatgaggcta ctagcgcatt ggacccgcaa acaacagaag aagtattaga cttattgtta
    19561 gcgatcaata agaaattgaa tttgaccatc gtcttgatca cacatgaaat gaatgtgatc
    19621 cgcaaaatct gcaacaaagt cgctgtgatg gagttgggga aagtcgtaga agaaggagac
    19681 gtattgactg tcttcagaca accgaaaaaa gaagtaacca aacgctttgt acaacaagac
    19741 atcgaaccag aagctgattc gacagaacta ttagctgaac tcatcaaaga aaatccaagc
    19801 ggccgtttgg caactttgac ctttagcgaa agaaatgcca acgagccagt catttcccaa
    19861 gcgattcgac gctataacat cgatgtcaac gttgtgtatg gaaagatcaa acaagtgaaa
    19921 gaaggttcct ttggttcatt gactgtcttg atgactggtg aaaccaaaga attagatcaa
    19981 gcagaagtgt tcatcaaaga acaaggagta ggaattgagg tgatccatcg tggataaaag
    20041 cttttcagaa acatatctag attttaaaca aatcaacccg gaaacgatga atcaggctat
    20101 ccttgataca ctatatatga cattaatctc aatggtctta gtgacgatca tcggattagt
    20161 tttgggattg atcctttact ctattggacg caaaaacaaa ccgtatgctc gaatcattta
    20221 tggaatcgta tcgatcatca gtaatatttt ccggtcaacg ccatttatga tcctgatggt
    20281 tttgatcatt ccatttacta aagcaatcgt aggcactatg ctaggtgcgc aagcagccat
    20341 tccagctctt gttttatccg cagcaccatt ttatgcccgt ctagtagaga ttgcttttcg
    20401 tgaagtcagc cctggtgtac tggaagcagc agatgcaatg ggagcaagtt actgggaaat
    20461 catctggaag gtcttgatac ctgaaagtat tcccgcattg atttctggat taacagttac
    20521 aacgatctcg atgatcggat ttactgcgat ggccggcgcg atcggcgcag gtggacttgg
    20581 aggtcttgct tggcaggaag gctaccagcg tggtaatcta acagtgacat tcgttgcgac
    20641 tttaattatt ttactaatcg tatttatcgt tcaaggaatc ggtgatttct taactaagaa
    20701 aacagacaaa agataatagg atataggggg atgtaggata tgaaaaagaa aatttttgga
    20761 tttgcagcag cgcttttgct gactgtagga ttagcagcat gcggtaacaa cagcgacagc
    20821 aaagattcag caaataaagc agacgacacg acattgaaag tcggcgcttc accgacaccg
    20881 cacgcagaga ttttggaaca tgtgaaacca ttattgaaag atgaaggaat cgatcttgaa
    20941 atcgtcaaat tcgatgacta tgtattaccg aaccaatctt tggaagaagg cgacattgat
    21001 gccaattact tccagcatat tccttatttg aacaaagaaa tcaaagaaaa aggatatgac
    21061 tttgtcaatg ccggtgctgt ccacatcgaa ccaatgggct tgtactctaa aaaagtcaaa
    21121 gatgtttccg aattaaaaga tggtgcaaca atcattactt caaattctga atcagactgg
    21181 ggacgcatca tcacaattct acaagatgct ggcttagtca aagtcaaaga tggagtagat
    21241 ctggaaacag caacattcga tgatattgaa gaaaacccta agaacttgaa gttcaaccat
    21301 acgatcgacc catcactttt agcttctacg taccaaaatg atgaaggtga cctagttgca
    21361 atcaacgcaa acttcgctta cggcgcaggg ttgaatccat tagaagatgc cgtattgctt
    21421 gaaaaggaca actctcctta cgtgaatatt attgcgactc gtaaaggtga tgaagacagt
    21481 gacaaaatca aaaaactgat tgaagtgctt caccgcaaag aagtccaaga atggatcaca
    21541 gacaaatggg gcggctctgt taaaccagta aaggctgatg caaaataagg tatggaacaa
    21601 aaaagatgag aaataagtct gtaatggctt atttctcatc ttttttatac ctattctaat
    21661 ttagaaatca aaattgttta ataataaata aaagatattt gattttagta aggaaggtca
    21721 ttgcgcttca ttctcaatta gtctaaaatg agtgagaacg aaagagaatt tgggggtata
    21781 atgcatgtct gtcttagaaa taaaaaatct acatgtgtcg atcgaggaaa aagaaatcct
    21841 taaaggcgta aacctaacaa tgaaaaccgg agaaatccat gccatcatgg gacctaacgg
    21901 cacaggaaaa tctaccttat ctgccgctat catgggcaat ccaaactatg aagtaacaga
    21961 aggcgaaatt ttgtttgacg ggaaaaatgt tttagacttg gaagtagatg aacgtgcgcg
    22021 acttggctta tttttagcta tgcaatatcc aagtgagata ccaggtatca cgaatgcgga
    22081 attcatgcgt gcagcgatca atgcgaaacg tgatgaaaac gacaaaattt ctgttatggc
    22141 atttttgaaa aagttagatg aaaaaatggc tttactaaat atgccagaag aaatggctga
    22201 acgttatctg aacgaaggtt tttctggcgg agaaaagaaa cggaatgaga tcctgcaatt
    22261 gttgatgtta gaacctacat ttgcaatttt agacgaaatc gattcaggtc tggatatcga
    22321 tgctttgaaa gtcgttgcta aaggagtaaa tgaaatgcgc ggagacaatt tcggtgcatt
    22381 gatcatcacc cactatcaac gattattgaa ctatatcaca cctgatgtcg ttcacatcat
    22441 gatggaaggc cgagtagtca tgacagggaa tgctgaccta gctaaacgtc tggaagcaga
    22501 aggctacgct ggtatcagta aagaattagg aatcgactat aaagaagaag aagcgtaagg
    22561 gggagcaaga atgaaagaaa aaaactggct cgattatctt gacgcggtaa atgatttttc
    22621 tttaagtaaa ggcgaacctg attggatgag aaccttccgt caagacgcac tagcgaaagc
    22681 agatgaactg ccattgccgc atatcgatcg ggtgaaattc catcgctggt cgttatttga
    22741 tgtgaaagaa acacaaacca tcagtgaaac aggcacgatt ccggcatttg atgcaatgaa
    22801 agacaatcct gtgcttgtcc aacaaggttc atggacgatt tttgaacaac tgcctgtgga
    22861 attagcagaa aaaggagtca tttttaccga cttgttcact gcaatgatcg aatatccaga
    22921 actagtccaa gaatattata tgaaaaaagc agtaaacatg aacgaagacc aattgactgc
    22981 actccatgta gcttttatga acagcggtat tttcctgtat gtgcctaaaa atgtcgtgat
    23041 cgatgaacca ctcgagtcct tattcattca agatggcgca tccgatgagc acttcttcaa
    23101 gcatgtgttg atcgtggcag atgaacatag tgaattttct tatctggaac gtttccagac
    23161 aaccaaagaa caagtagcaa aatcatcagg taatatcatc gtggaagtca tcgctaaagc
    23221 tggttcaaaa atcaaatatt cagccgtaga tcaattagga gaaaatatta cttcttatat
    23281 gaatcgccgt gggcacattt tacgagatgc ttctgtcgac tgggcaattg gtgtcatgaa
    23341 tgacggtcat gtgatcgctg actttgactc agatttagca ggagaaggtg cacacgcaga
    23401 agtcaaaatc gtggcaatca gctcgggcag acaaatccaa ggaatcgata cacgagtaac
    23461 caataaagcc cctcatacga tcgggcatat tttgcaacac ggagtgatcc gagaaaaagg
    23521 aacattgacc tttaatggta tcggccacat cttgaaaggg gcaaaaggtg cagatgccca
    23581 acaagaaagt cgtgtcttga tgctttctga taaagcacgt ggtgatgcga atcctattct
    23641 tttgatcgat gaaaacgaag taactgctgg acatgctgcc agtgtaggac gagttgatcc
    23701 agaagaaatg tactatctga tgagtagagg attgcataaa gaagaagcag agcgcttagt
    23761 gattcgagga ttcctcggtt ctgtcttaac agcaatccct gtagaacaag ttcggaaaga
    23821 attagtcgaa gtaatcgaag ggaagttgaa tggatgatcg atgctaaaaa gctacgcaat
    23881 gattttccta tcttatttca agacgtcaat gatgaacctt tagtttatct ggataatgca
    23941 gcgacgaccc aaaagccaaa acaagtactc caggcattag cgtactatta cgaacacgat
    24001 aacgccaatg ttcatcgcgg tgtccatacg ttagcagaac gcgcgaccca tgattatgaa
    24061 caagcaagag aaaaagtacg ggcgttcatc catgcaaaag aaacagcaga agtgctgttt
    24121 actcgtggta cgacgacaag cttgaattgg gtagccagaa ccttcggcga ccgctatatc
    24181 aaagcaggag acgagatagt gctctcttac atggaacatc attctaatgt tatcccgtgg
    24241 cagcagttgg caaaacgaac aggtgctgtc ttgaaatata tcgaactaac agaagaaggc
    24301 ttcctggata tggaggatgc agcgaaaaag attacggaca aaaccaaaat cgtctccatt
    24361 gctcatgtat ccaatgtctt aggtgtcttc aatcctgttc aagaattagc tgaacttgtc
    24421 catgaaaacg gcggggtcat cgtagtagat ggtgctcaat ctgccccgca catggccatt
    24481 gatgtccaag cactagactg tgatttcttt gctttcagcg gacacaaaat gtgcggacca
    24541 acaggtattg gtgttttata tggtaaacga aaatggttag aagaaatgga acctgttgaa
    24601 tttggtggcg aaatgatcga ttttgtcgaa ttatacgaca gtacatggaa agaactacct
    24661 tggaaattcg aagcagggac accaaatatc gccggcgcta tcgcattagg ccatgcaatc
    24721 gattatttgc aaaaactcgg tatggacaat atccatcgat atgaagaaga actagccgct
    24781 tatgtgttgc caaaattaca agcaattgat ggattgactg tttatggtcc acaagacccg
    24841 aattttcgga caggagtcgt tgcattcaat ttggatgggt tacatcccca tgatgtcgcg
    24901 acagctttag acatggaagg ggtagccgtc agagcaggtc atcattgtgc gcaaccgcta
    24961 ttgaagtacc ttgaagtatc agcgactgct cgcgcgagct tttatttcta caacacaacg
    25021 caagacgccg accgtttagt tgaagcaatc atggcaacaa aggagttttt ccaacatggg
    25081 actatctaaa ttagacaatt tataccgtca agtgatcttg gatcattctt cccatccgca
    25141 tcatcgtgga agcttgactg actcgacaag caagatcgaa ttgaacaacc ccacatgtgg
    25201 agatgtgatc gaattgcaag tcgatgtaaa agacggaatc atcaaaaata tcgcctttga
    25261 cggcagtggc tgctccatca gtacggcaag tgcctcgatg atgacagacg ccgtcatcgg
    25321 aaaatcaata gaagaagcag aacatttaac tgtagacttt ctacagcttg tccaaggaaa
    25381 agaagtcaaa gatcccgacc aattaggcga tgctgctatg cttggtggtg tagctaaatt
    25441 tcccgctcgg atcaaatgtg cgacacttgc ctggaaagca ctaggaaaag caatggaaaa
    25501 cgatggtacc gcagctttcc atcattacca caaggaagag gagtgagaac atgggcgtac
    25561 cagaattaga agaatataaa ttcgggtttc acgatgatgt cgaaccggtt ttcagtacag
    25621 gagaaggctt gacagaagaa gtgatccgtg agatgtcaag aatcaaaggc gaaccagaat
    25681 ggatgcttga attccgtctg aaatctctag aaacatttaa caaaatgcca atgcaaacat
    25741 ggggccccga cctttcagac atcgatttcg atgccatcaa atattaccaa aaaccaagtg
    25801 acaaacccgc tcgtgactgg gaagacgtac cagaaaaaat caaagataca tttgaaaaga
    25861 ttggtatacc agaagctgaa cgagcttatc tagccggtgc ttccgcacaa tatgaatcag
    25921 aagtcgtgta ccataatatg aaagatgaat tcgaaaagtt aggaatcgtc tttactgaca
    25981 ctgactctgc tttgaaagaa taccctgaat tattcaaaga gtacttttca aaacttgtac
    26041 cgccaaccga caacaaatta gcagcgctga attcagccgt atggtcaggt gggaccttta
    26101 tttacgtgcc aaaaggcgtc aaagtcgatg ttccattaca aacgtacttc cggatcaatg
    26161 cggaaaacac ggggcaattc gaacgtacgc tgatcattgt tgacgaagga gcaagcatcc
    26221 actatgtcga aggttgtacg gcacctactt attcaagtaa cagcctgcat gccgccatcg
    26281 tagaaatctt tacaagaaaa gatgcgtatt gccgttacac aacgatccaa aactggtcag
    26341 acaatgtgta caacttagta accaaacgag caaaagcata cgaaggcgca accgttgaat
    26401 ggatcgacgg aaacctaggt gcaaaaacaa cgatgaaata cccaagtgtt tacttagatg
    26461 gaaaaggtgc acgaggcacc atgctctcca tcgcctttgc aggagcaaac caaatccaag
    26521 atacgggtgc aaaaatgatc cacaatgcac caaatacatc tagctctatc gtctctaaat
    26581 caatttcaaa agacggcgga gaagtaaact atcgaggaca agtaaccttt gccaaaaaca
    26641 gtgcgggttc gatctctcat atcgaatgtg acacgatcat catggacgaa tggtcgaaat
    26701 ccgatacgat cccattcaat gagatccaca acagccaagt ctctttagaa cacgaagcca
    26761 aagtctcaaa aatctcagaa gaacaactct actatctgat gagccgaggc ctgaccgaat
    26821 ctgaagcaac tgaaatgatc gtcatgggct ttgttgaacc attcaccaaa gaacttccaa
    26881 tggaatatgc agtcgaactc aatcgattga tcagttatga gatggaaggg tctgtaggtt
    26941 aataactatt tcattgctcg aaacgttgat attaaagcgt ttcgagcgtt tttttatttg
    27001 tattttaatg gttggctacg tttttggcta cgtttggaat tattcgccca taaattttgc
    27061 aaatcggtca ccagttttct taacagattg tggtgtgaca tgagcataga tattcatggt
    27121 agttttaata tctttatgac ctaatcgttc ctgtacttct tttatcgacg caccactttc
    27181 aaacaataag ctacagtggg tatgcctaaa tccatgtgga gtaatttgag gctccatcgg
    27241 tgtctttttg taaatccagt ctaaccaatc gtttactact tgggggtagt acaacttgtt
    27301 tgtgtttgta gtgaaaagaa actgttttgg tgaattcgtg ttatagccat ataagatcat
    27361 tattttcatt tgttcttgtt gccaaatacg cagttgttta agtgtaaaat catcaagctg
    27421 aatcgttctt gatgaatttt tagttttagg tacttgtaga actacttgat taaactcgtc
    27481 ttgagcgata gttttaccaa ttgttattgt tttattgaaa tagtctatat cttcccattg
    27541 aagcgccaat gcttcgcttt tacgcattcc tgtataagct aataaacgga aaaaagtgta
    27601 cagtttaact gaattatttt ctttagtatt ctgtaaaaac agttgtaatt gatctttcgt
    27661 gtaaaacttc aagggttgtt cttcttcaat ttttcttgga agcaatgttt tagacatagg
    27721 attatcctta cagacttcca ttgctactcc aaatttaaat atttgagcag ttgtttttct
    27781 caagaaacca tattgtttta atgttttgtg ccattcattc acctgttttt ggcaatagct
    27841 aacacttatt ttatccaatc gtaattcccc aaaagcaggt aatatatggt ttttgcaaaa
    27901 acgttgagca acggcaacag aagacggttt tactcttgtt ctgtagttat caatccataa
    27961 ttcatacaac tcttgaaaag ttgtaacatt gattttaaac tcttgttttt ctttaaagtc
    28021 tacaagtagt ctattaagtg ctgtttgcgc ctcagctttt gatttgaatc ttctacgctt
    28081 tgtacgtata tcttttccag tcttgggatc tttccctaaa taagtttcaa atccccaata
    28141 tttttcgcca ttttgtaatt tataactaaa aaatgttgcc atttgattct ctccttactt
    28201 cattattgca ggtagagaag ttatttgaag aatcaattat ttttaaattt atcgtgatta
    28261 tcagttaaaa attttgcgat tatactattt ttctcatatg ggaaattgta ttttttacta
    28321 agatctgaaa taaatttttc tgtttcaaat tggtttttag taattttata aaagaaatcc
    28381 tcgacagatg aatactttga aatatcttta taggctaagt ccatttcgtc taatagctgt
    28441 tttaaagaat caatcattct ttctttttca ccgtatttga aatcaccatt tcttatcttg
    28501 tcttgaagtt tactgttggc tcttttgaaa aatagctctt tagagataga gtgtctttgg
    28561 ttagcgtact cttcaatcag aggattgata ttattagcaa gtatctcatt tagataaatt
    28621 tcaaaatctt ttgagtaata ttttgtaaat atatttttta ttataggatt caataactca
    28681 tagtctttat ctagcgaaaa cgtatcacta tatctttctt gaatgtcttt aaagactttg
    28741 tgaggtattt ctgggaagtc cttaatatat agctcatacc ctatatcgat aaggtatgaa
    28801 gttatatatt cttctaaagt tccccattta atccagtcaa ttgttgaatt agtgatagtt
    28861 gataataatt tcagcttttg tggatttggt aaattggtcc cacgttccca gttggatatg
    28921 gtcgcacgtg gtgaattatc tattttcctt ccaagttctt ccatagtaaa accacatgaa
    28981 aggcgtaatt gtttgattcg ttttcctgct tctgaaggat ttggcttcat cttttttctc
    29041 ctttttattt ttaaagatag tatatcatat ttataaaata aaagtattta aaagtattta
    29101 ctttttatct ggagtatgat actttattct tataaataca aataaataca tttttttacg
    29161 caatttgtat ttatttgtac ttataaaggt agaggagtta tagaataatt aattaaaaag
    29221 gagaggtttt tgtggaagca ataaaattaa tgatttcaga agaacaggag gaaatgtttc
    29281 taaagcagtt ttatcaaatt gctacaaaag ctattgaaaa ggctcaagaa aatgcgggga
    29341 tgacaaggga atatctcaat caaaaagaaa tggcggaata cttaaatgtg agtgaaaact
    29401 ttttaaaaaa tgctgtgaga aatgagggat tgcccgtagt tgaattaggg gcaagaaaat
    29461 tttattcgaa aaaggcagtt aatgagttta tgtttgctcg aatgaaaaga ggggaaaata
    29521 ttggaagatg atgaagtaga aattataaaa aaatgcttta aaaaaagaaa aaaagtgttc
    29581 ccaaaagttt gcagactggg ggaacactca ataataaagt gctgagaaaa ctttatttat
    29641 agctattata tcaaaaaaga aggtgaaaag gtgttttctt ctggaaatgt tgtagttgac
    29701 aaacttagag aaataaattt tgacggaaat gtaatccaca cacatggtac gatcaattaa
    29761 gaaaaaaaac gaaaaaaggt gttgagaagc cctatttgaa tgcaatagtt atcttagcag
    29821 aaattaccta ttggtataga cctaaaaaaa tttttaacga tgatggtcag ctacttggtt
    29881 atcaaaaaaa gtttcttgaa gatattttgc aaaaatcata taagcaatta agcaaaaaaa
    29941 caggattatc agaacgagct ataaaagatg caattgtgta cttagagaaa aaggggatta
    30001 tcaaaagggt ttttagaaat atttattatg agaaaagagc agttacatta tcaaatgtta
    30061 tgtacattgt tttaaatgta cataaattga tagaaattac ttttcctact ttggattgcg
    30121 aaaaaaagga gtatatgccg aaaattcgtc agaggggtat cgaaaaaaag agatatgtct
    30181 ctttaaaaaa aggtagaggt atgtacaaat ttgtatatac gtatacaaag actacttcac
    30241 agaacatatc aaagactact ctcgttatgg aagaagagga tattaatata aagaggattt
    30301 acagtaagat tagtgttctt tatgacgcaa ataacgaaga tggtcgaaaa ttatttcaag
    30361 tgtatcacta tttgagaaac gctaatgtag atacagaaga tatcagaaaa atcattgaat
    30421 atttatctga aaatactcag tatcttattg ctgagtgtat tataaaacaa catgaagcat
    30481 gcttttttca aagaaaaact gaagaagggt tatacgatta tgtaacatat tttttgaatg
    30541 gacttcagaa aagatataaa agtcaatttt tagaaaatgt agagcctata gatcagttca
    30601 aaaaagcttt cgaaatcaaa gagttacctg aaattactat gcataattgg ttgaaaggag
    30661 aagaatcatg attaaaaatc gcttaataga tcaaatgtgg tgtcttgatc aaaatacaga
    30721 tactctcgaa ttaatcgaga gtatctgctt caacacagta gttctcgatt taagagctga
    30781 aaatgacaat tgtgtaactc atatcataat taatcaaaaa atggctcagc agctctctga
    30841 gagcctaaga aaatgggctg aaggagaaaa ctatgaaagc aattaaagaa aaaatcgtta
    30901 gtagaaaaat aaactggtta gcactcagtg tacttgtttt aatgattagc gttgttttta
    30961 caagtaatat tgttgaagct agcattttca attggtttga tgacacaaaa agtcaaacag
    31021 agtttttgaa taattctctt tatagacctt acctaaaaaa atacaatgga gatttcctta
    31081 gtcagttcgg gatttggctt ggatgggctg tggtaaaagg catgtttact gtgactgatt
    31141 cgattcaaaa tatgattcca gatgtgttgg atttgttcaa tttcattgaa agtacagggc
    31201 taaataatgt ttatcaatca gtcataaata caattgtcgt tggattaatg atcctttcat
    31261 tgatgtttgt tggctacaag atgattactg gaaaaggaac aatagattta agatctgttg
    31321 gaatgaatat agtgatgtct gtagcgttaa ttcttttaat gccaacaatg atttctagcg
    31381 gtattcaatt tgccaaaata ttttacaatg atgctactac gattacaaat tcagatgacg
    31441 gagtcgcttg gtcattgata aaacaaggag taacagatct ggcatatatt aataaaacag
    31501 atcaatactc aagcattgat aaaacggagg atcgaaataa gttaacacga aaaaattttc
    31561 aacagacaga tttaacacaa gtgttgacgg ataaagtgat tgataaattg gaaaaagaaa
    31621 atccagctgc ggataatctt cgctatgaat
//
LOCUS       DAFEKH010000032        30349 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.033, whole genome shotgun sequence.
ACCESSION   DAFEKH010000032
VERSION     DAFEKH010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30349
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.033"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            170..514
                     /locus_tag="LP386_001652"
     CDS             170..514
                     /locus_tag="LP386_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBL1918890.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            515..934
                     /locus_tag="LP386_001653"
                     /pseudo
     CDS             515..934
                     /locus_tag="LP386_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
     gene            complement(1026..1376)
                     /locus_tag="LP386_001654"
     CDS             complement(1026..1376)
                     /locus_tag="LP386_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918891.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1342..2673)
                     /locus_tag="LP386_001655"
     CDS             complement(1342..2673)
                     /locus_tag="LP386_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HBL1918892.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            2929..3495
                     /locus_tag="LP386_001656"
     CDS             2929..3495
                     /locus_tag="LP386_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL1918893.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3640..3727
                     /locus_tag="LP386_001657"
     tRNA            3640..3727
                     /locus_tag="LP386_001657"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3672..3674,aa:Ser,seq:cga)
     gene            4061..5035
                     /gene="bsh"
                     /locus_tag="LP386_001658"
     CDS             4061..5035
                     /gene="bsh"
                     /locus_tag="LP386_001658"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HBL1918894.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGERKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
     gene            5360..7255
                     /gene="asnB"
                     /locus_tag="LP386_001659"
     CDS             5360..7255
                     /gene="asnB"
                     /locus_tag="LP386_001659"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBL1918895.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEKWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(7450..7896)
                     /locus_tag="LP386_001660"
     CDS             complement(7450..7896)
                     /locus_tag="LP386_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBL1918896.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            8124..8273
                     /gene="rpmG"
                     /locus_tag="LP386_001661"
     CDS             8124..8273
                     /gene="rpmG"
                     /locus_tag="LP386_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBL1918897.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPREREVTL
                     HRETK"
     gene            8361..8879
                     /locus_tag="LP386_001662"
     CDS             8361..8879
                     /locus_tag="LP386_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBL1918898.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(8956..9912)
                     /locus_tag="LP386_001663"
     CDS             complement(8956..9912)
                     /locus_tag="LP386_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL1918899.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            10078..10884
                     /locus_tag="LP386_001664"
     CDS             10078..10884
                     /locus_tag="LP386_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1918900.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            10881..11870
                     /locus_tag="LP386_001665"
     CDS             10881..11870
                     /locus_tag="LP386_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBL1918901.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            11867..12871
                     /locus_tag="LP386_001666"
     CDS             11867..12871
                     /locus_tag="LP386_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBL1918902.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILLSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            13003..13545
                     /locus_tag="LP386_001667"
     CDS             13003..13545
                     /locus_tag="LP386_001667"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HBL1918903.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            13565..14263
                     /locus_tag="LP386_001668"
     CDS             13565..14263
                     /locus_tag="LP386_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HBL1918904.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            14284..14496
                     /locus_tag="LP386_001669"
     CDS             14284..14496
                     /locus_tag="LP386_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HBL1918905.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            14496..15458
                     /locus_tag="LP386_001670"
     CDS             14496..15458
                     /locus_tag="LP386_001670"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HBL1918906.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            15476..15871
                     /locus_tag="LP386_001671"
     CDS             15476..15871
                     /locus_tag="LP386_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBL1918907.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            16034..16399
                     /locus_tag="LP386_001672"
     CDS             16034..16399
                     /locus_tag="LP386_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HBL1918908.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            16396..18207
                     /locus_tag="LP386_001673"
     CDS             16396..18207
                     /locus_tag="LP386_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HBL1918909.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTNENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(18269..18436)
                     /locus_tag="LP386_001674"
     CDS             complement(18269..18436)
                     /locus_tag="LP386_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HBL1918910.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            18684..19673
                     /gene="galE"
                     /locus_tag="LP386_001675"
     CDS             18684..19673
                     /gene="galE"
                     /locus_tag="LP386_001675"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HBL1918911.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            19685..21169
                     /gene="galT"
                     /locus_tag="LP386_001676"
     CDS             19685..21169
                     /gene="galT"
                     /locus_tag="LP386_001676"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HBL1918912.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            21193..22173
                     /locus_tag="LP386_001677"
     CDS             21193..22173
                     /locus_tag="LP386_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1918913.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            22364..23086
                     /gene="tsaB"
                     /locus_tag="LP386_001678"
     CDS             22364..23086
                     /gene="tsaB"
                     /locus_tag="LP386_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HBL1918914.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            23070..23612
                     /gene="rimI"
                     /locus_tag="LP386_001679"
     CDS             23070..23612
                     /gene="rimI"
                     /locus_tag="LP386_001679"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBL1918915.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            23619..24083
                     /gene="rimI"
                     /locus_tag="LP386_001680"
     CDS             23619..24083
                     /gene="rimI"
                     /locus_tag="LP386_001680"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBL1918916.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            24080..25096
                     /gene="tsaD"
                     /locus_tag="LP386_001681"
     CDS             24080..25096
                     /gene="tsaD"
                     /locus_tag="LP386_001681"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HBL1918917.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(25705..26406)
                     /locus_tag="LP386_001682"
     CDS             complement(25705..26406)
                     /locus_tag="LP386_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBL1918918.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            26867..28096
                     /gene="arcA"
                     /locus_tag="LP386_001683"
     CDS             26867..28096
                     /gene="arcA"
                     /locus_tag="LP386_001683"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HBL1918919.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            28187..29206
                     /gene="argF"
                     /locus_tag="LP386_001684"
     CDS             28187..29206
                     /gene="argF"
                     /locus_tag="LP386_001684"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HBL1918920.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            29321..30268
                     /gene="arcC"
                     /locus_tag="LP386_001685"
     CDS             29321..30268
                     /gene="arcC"
                     /locus_tag="LP386_001685"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HBL1918921.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
BASE COUNT         9919 a         5198 c         6319 g         8913 t
ORIGIN      
        1 aaaaaaagcg ttagcaacta tgcttaaaaa gcatatcgac tgaataaact aagcattgga
       61 caggctgaaa gactacattt aaaatgaaat gcgaagaaac aatagaaaat aaagttgcct
      121 tagaaccata gttgaatcac ctaacagtcg tgaagggaga ataagagaaa tggcagaaaa
      181 acaaaccgca ggacgagatc aattaggaga ttttgcacca aaatttgcag aattgaatga
      241 tgatgtttta tttggacaag tatggtccag agaagaatta tctgctcatc agcgtagtat
      301 catcaccata tctgcattaa tttcaggagg aaattttgaa caattgccag ctcatctgaa
      361 gattggcaag caaaatggca ttactagtga agaaatagca gaaatcatta cccatttagc
      421 tttttatgta ggatggccaa aagcttggtc agcttttagt ttagcaaaag aaatctattt
      481 agaagaaaat agcgaagata agaaagaggc gtaaatgacg acaaaacacg aagaaataca
      541 caatggcgtg atttttccag caggtgaaaa aaacgaagct tacgctcaag tatttaccgg
      601 gtaaagctat ctgaatatgt tagtgaatga tcccgaagtt tctgttggtg taggtaatgt
      661 aacttttgaa ccaggttgtc gcaatcactg gcatgtccat aaagacggct atcaaatctt
      721 acttgtgacc ggaggagaag gctggtatca ggaagaagga aagccagcaa gacgattaat
      781 ggctggagat gtcgtcgtaa cgcacaaagg gattaaacat tggcatggtg cgacaaaaga
      841 cagttggttt gaacatttgg cgatcactgc tggtaattca gagtttttag aacctgtaac
      901 agatgaagtg tatgaaggat tggaaaatca ataatgtcaa gcttgaacag ctcctgaaag
      961 tagattttaa tcgaactttc aggagctgct tttttgattc agtcttttat aaatagaaaa
     1021 tagggttaat aataggaatg agaagcacgt cgaaagatct taatattgat aatcggctgg
     1081 gcatacatga tttccacgtc atcaatcaaa ctacctaaca gatgataatc ttcccgatca
     1141 tgtcggggat tacctaatag ttcttgataa tagatttcca tactagggtc ccgaggattg
     1201 ttcagcaaat cagcaagtac atctaaatct tctggctgag tttctgccgt accctgtatc
     1261 tctatgaaaa gcccttcctc agcaaattct actccaatac gtatttcagt tatttcatgg
     1321 gaatataaat aagtaagaag ctcatcgatg attctttttg ataattcttt ttccaagtgt
     1381 ctttttttcc tttctgacag cggtaaagtt atctagtatc ggtacaagga tacctgcaac
     1441 gaaaccagtt gaaaaaccac tgttatatag atttagtcct ccgtgcaaag tgctgacgtt
     1501 atggacaaga gcaatatgta gtacaccagc tattacaccg taaaaactgc cgtaaaaacc
     1561 gcttatgggc gcgagacctg tcccaaacac agctgcaaca agcatgccag tactggtgat
     1621 ctcatgaaaa gttccaaaca aagaagcaat aaatattccg actagtatcg gaaaactgtt
     1681 ttttaaatga caaccaaaag cactgaaacc caccgcagat aaaatagcac cgatgacagg
     1741 tccatttaac tgaccgccaa ccagcaaaac ataagaagac agcatcagac caactaagcc
     1801 tatgttgatc aaagtagcac caataccaga attagcaatg aaatcagttg tcaattttcc
     1861 agatgaatcg aaaatttctc gaatccccaa aagccgaaag gaattataat agaaaccaat
     1921 tccgactgtc agcgaaaaaa agccaaaaat aatccaaatg agaggaaagt gatattcatt
     1981 gaaaaccaat gtattttcga cgattgaata gctgaataac ctcaaaacag cagtaaaagt
     2041 catcgcaatc aacccagagg tgaatccaat attataaagt gtgaatccac gatggaaaac
     2101 taaagtttga gcagctaagg gcggaagaag tagaccaatt gctatgccag ctaaattccc
     2161 caataaaata cctatcagta aaggaaaacg cataccaaaa gtgatataac taacgaccgg
     2221 tgataatgcg ctaccaaaca gtccgatcat gatgtactga gaaaaaggtt tattgacaaa
     2281 tacagcgtat agatacacac ctaaaatgat tgagatagaa ttataaaggt ttttgccaaa
     2341 aaaagagaaa ccggtaactg ttagaatcga agcaaataag ggaccgttta aaatcacctt
     2401 gtgccgataa gctaaaagca cagaaagtaa ggtcaaaatc cctacattta tgaatgcgct
     2461 tccgaaaccg cctaaagcaa aataatctgt caaaagattg cttggcgagg taagaatagt
     2521 tagcaatcca ctccaattat cagtaggagt attagaaagc aagccaataa aaagaaaaaa
     2581 aacacctgta aaaccaagat aaaaatactt tcttttctgt gaaacgattc gtttttgagg
     2641 atgaatataa ataacgtcag tttcgttttc cattacacac cttctttttc attttcttta
     2701 actataactt gaaatgaaag atttggacaa ctatcattta ggtcaaaact aaaaatgtaa
     2761 gggaacccat tgaatttaac caaatttttt taattttgca aaaaaaagtt aaagaagact
     2821 gaaaaaaaat ttaaaatata acgttttgag taaaatgttt gcaaaaaatg ctaaaaatag
     2881 ggtacaataa aacaacatat actgcagtaa agaagtgggg gagttttaat gagaagaaaa
     2941 gtctatacca aggatcaaat tctaaaagct gcttatgatg ttgttgcaaa ggaagggttt
     3001 aaaggattta ctgcgagaaa tattgctaaa aagatgggga tttcgacaca gccgatttat
     3061 ctggaattca aaaacatgga agatttaaaa aatacgttgc tggattctat ctttgaacaa
     3121 ctaaaagaag atgttttccc tattgaacgt actggtgata aaatcattga tctcggtttg
     3181 aactatatct actttgcaaa aaagcatcat agtctttaca tggcattgta cattgatgaa
     3241 catggggacg gaaagaaaat gcatgatttt tcatacaatt atttccgtga aatagttaaa
     3301 gaagatgaaa gatacaatca attatcggat gaatatgtcg atgctctgca tactggtaca
     3361 tgggtagcag tgactggctt agcgtcattg atgtcatcaa acatcatgca tccaacagaa
     3421 gaacaaatca ttgcactgat caaacggaca attgactcga ttttagcatt agataatcct
     3481 gaaataatca gatagtgttc tatcagtatg aatttgatcg gtaagtccgt tggctgcaaa
     3541 ctgtcaatgg acttttttgc taaaaaaagc gatttctgtt atttatctat tagaaatagg
     3601 cttgacattt cgtgaaaaaa gtttaaaaat agtacttacg gaaggttggc agagtggtaa
     3661 tgcaccggac tcgaaatccg gcgaaccggc taataccggc gcgcaggttc aaatcctgta
     3721 ccttccttat atcaacgatt agaggttgtg aagaagctgt cctgcatcaa gtaataagaa
     3781 cggccaaaca aaaatagctt ttcctatttt ttcgtttgat tgggcttatt accgcagatg
     3841 caagcttttg aacaccgttt gttcggaata aggggctgtg acaagacttt tgtcacagcc
     3901 ccttattgtt gtacttttaa cctacaatat tttttgattc cccctgagta ctatttttta
     3961 taaatgctag taaatcaatc ttctttggcc tttttttgat aaaaaaaata ctagatgtaa
     4021 gataaaagtg taaaaacgat ttgttttagg acgggaaacg atgtgtaccg caatcactta
     4081 tgcaacgaaa gaccattatt ttggaaggaa ttttgattat gagatgtctt ataatgaagt
     4141 ggtcactatt actccaagaa attatcgttt cgattttaga aaggtaaaaa atttagataa
     4201 acattatgca atgataggaa tagcagctgg ggtatccaac tatccactct attatgaggc
     4261 tacaaatgaa aaagggttga gtatggcagg actgaatttt cctggcaatg ctgattataa
     4321 agaattacaa gaaggaaaag ataacgttgc accatttgag tttattccat ggatactagg
     4381 gcaatgctca accatagacg aagctaaaga attattggct actatcaatc tagtcaatat
     4441 cgattttagt gaaaaactac ccttgtcacc tttacactgg ttattagctg ataaagaaaa
     4501 atcgatagta attgaaagta tgaaagatgg acttcattta tatgataatc ctgtcggtgt
     4561 gttgacaaat aatccgccat ttgattatca attatttaat ctgaacaatt atcgctcgct
     4621 atcaaatgga acaccagaaa atcatttttc aaaccagatc agcttgaatg tttatagtcg
     4681 tgggatggga ggattgggct tacctggaga tctctcttct gtttctcgat ttgtaaaagc
     4741 cacatttact aaaatgaatg ctgcatcagg tgattcagaa tctgaaagta tcagtcaatt
     4801 ttttcatata ctaggctcag tcgagcaaca aaaaggagta tgcgatactg gagaaagaaa
     4861 atacgaatat acgatttatt cttcttgctg taacgttgat aaagggattt attattatcg
     4921 tacgtatgaa gacagtcaaa ttactgctgt aaatatgaat aaagaagact tggatcgtca
     4981 tgaattggtc agttatccag tcataaaaga gcaacagata aactatgtca attaattaat
     5041 gaatagatcc gtttggtatc atattttctg atacagtcat aattagacac gatctttagg
     5101 tcgtgtcttt ttttgctggt ttttttggaa atagcatcca ctaatatttt tttaacacga
     5161 agagaataag gtagcctcaa aaaagaaaac atggtaaatt agatattggg actttatttt
     5221 ctgtaaaaac agaaactttc atcttttgtt ttcacgtgac gaaattgtaa gagagaaaat
     5281 attcgtccgc tatttattct atgataagat gcatatgaat gaaataaaca gtaattttat
     5341 attaggatgt gaaagttaaa tgtgcggtat tgtaggtttt gttaacgaca aggacaacaa
     5401 aaaaacaatt attaatacaa tgatggatcg aatcgttcac cgtggaccta atagttcagg
     5461 agaatatatc gataaacatg ttgctttagg attcagaaga ttaagtatta ttgacttaga
     5521 gggcggtact cagcctattt acaatgaaga tcggacaaag atcattattt ttaatggcga
     5581 aatctataat taccagcctt tgagagaaga attgattgca gctggccacg tttttcaaac
     5641 acatgcagat acagaagtcc ttttgcatgg ttacgaagaa tggggaacag aattattgca
     5701 aaagatccgc ggaatgtttg cttttgctat ttgggataat gaaaagaatg agttattcgg
     5761 tgcaagagac cactttggga tcaaaccata ttattatgca gaaatgaacg gaacatttat
     5821 gtttggttca gaaatcaaaa gttttctgcc tcatcctgat tttaacaaag aattgaacaa
     5881 agaagcgttg aaaccttata tgactttcca atattctcca ttaaacggcg aaacattctt
     5941 caaagatgtc tatcgtttgc ctgaaggcca ttattatacg tataaagatg gaaaaataga
     6001 cattcagcaa tattgggatg cagattttga aacaaaagaa acgcattccc gacaagaatg
     6061 gatcgaaaaa atcgacgaaa ccgttcaagc ttctattgaa gcacatacgg tcagtgatgt
     6121 agaagttggt tctttcttat ccagcggggt tgattccagt tatgtaacct ctgtattgaa
     6181 accagatcat tctttctcaa tcgggtttga tgataaaacc tataatgaag cgattgaagc
     6241 cagaaaacta accgaactat tggacttaga taatacagca gcagtgatcg acggagacat
     6301 gtcgttcaaa gcattccctt tgatccagta tcacttagat gaacctgatt caaatccttc
     6361 ttgcgtacct ttgtactttt tagcaaatct tgcttcacaa agtgtgcggg tagtccaatc
     6421 tggagaaggg gcggatgaac tgtttgcggg ataccaaacg tatggattcc atacgaattc
     6481 aaaattcatc cgtgtgattg ctcaaggatt gaaaaaatta ccaaaaggaa cacgctataa
     6541 tttaggacgt aaaatcggaa aaatgaaaaa tttccatgga cggatccatt tatatgaatc
     6601 acttgctcct gcaaaagaat attttatcgg tcatgctcga gtgttcgaag aatcagaagc
     6661 atcagaagtg ttaacaccaa aatatcaaac agcaccatct gtggatgaaa tcatgactgt
     6721 tcattacgag aaaacagaag gaatcaaaga tgaagtcaat aagatgcaat atgtcgatct
     6781 tcatcaatgg atgccaaaag atatcttgtt aaaggcagat aaactttcta tggcaagttc
     6841 tttggaagtc cgagtacctt tattggatat cgaagtcatg aaattggctc aacaaatacc
     6901 aagtaagttt ttattgaatc aaaacaacac aaaagatatt ttcagacaag ctgcgaacaa
     6961 acatcttccg gaaaaatggt cgaatcgtgt gaaattagga ttccctgtgc caatcaaagc
     7021 ttggttgaaa gaagaacacg gctacgaaca agtcaaagca ttgttcgaag cagattttgc
     7081 aaaagaattt tttgatcaag aaaaaatcat gaagttgcta gatgaccatc acgaaggacg
     7141 taaagaagag caaagaaaaa tctggacaat cttcagtttc ttgacatggt ataaagtcta
     7201 ctttgtagat gaaacgattc cgcaagcaga agcaatcgac tatgtgactg tttgatgaaa
     7261 atcaaatatc aataaaaaag aggttttctc ctaccgttta acactgagtg ataagaaaca
     7321 atttcaaaaa acagctcttc ccgttttata gatattatga cttatggttc ggagttggca
     7381 gaggaacacc attgtttcga acataagggg gttgtgacac gattttcgtc acaacccctt
     7441 tacatatgtt caataatcga tttctttttc ttttgtccca tcttttttat aaatgaacaa
     7501 agttgattct ttgttttgtg ctacttgctt tcctttttcg attgcttctt tttttgtatc
     7561 aaaatggttg cttgcctttt ttgccccttt agatttcacg atccattgtt cttcctcata
     7621 ttctacgatc acatctgaat caagcagttt tccagcacga ggattcgtat cgtgttcatc
     7681 cgtcttgctt ggattttttt ctttttcgaa agttcgtttt tctgattcac tagcatcttc
     7741 ataccatttt tttgcttgat caatggcaat tgggatcgca cggttatcag ggtacccttc
     7801 atctaataat gcatttgcga tgtcgattgc tttttttctt gtcaatttat ctaagttttt
     7861 cattgatgca ggaaagtcct tcatgttcca tggcatatta gtatccccct ttattaaaaa
     7921 acataatcta tataaacaag tgtaagggta tttatacaaa aagaaaaaga ttttgtttga
     7981 gaagtaaaac cgttgtattt atcgtcaagt agttttactt aacaaaatcg tgaaaaacac
     8041 tagcaatcta gaaaaaatca tggtaagata atcaagtctg agagtcatct tagaggattc
     8101 ttgtaaaaat gggagggaaa aacatgcgcg taaacatcac tttagagtgt acttcttgta
     8161 aagaacgtaa ctatctaaca agcaaaaaca aacgtaacaa tcctgatcgt ttggaaaaac
     8221 aaaaatattg cccacgcgaa cgcgaagtta ctttgcaccg tgaaacaaaa taatgttttt
     8281 aaagttctca attccttgct ggtcaaagaa ttgagacttt ttttatctca aaacatctaa
     8341 aatcataagg agcggataat atgtttattt ccatgtgggc acaagataaa aatggtctga
     8401 tcggcaaaaa tggtttgtta ccatggcgat tgccaaatga tatgcgtttc tttcgcgaac
     8461 atacaatgga tcgaatttta gtgatgggaa gaaagaccta tgaaggaatg ggggatcttt
     8521 cacttcctta tcgccatatc atcgtgttga caacgcagcc aaattttcgc acgaaagaaa
     8581 atgcggaagt aatgcattcg atcgatgaac ttttgtcgta tagtcaaacg atctcagaag
     8641 atatctatgt ttcgggtggt agtcggattt ttcaagaact tcttccttac actggtcgga
     8701 tctggcgaac attgatcgat agcacgtttg aaggcgatac gtatattggg aatattgatt
     8761 tttcagactt cgcccttata gaggagtatg aggggataac ggatcaagaa aatctatatg
     8821 cccatcgttt tcaaaaatgg gaaagagtaa aaaatagggt tgcttcaaaa gaagaataaa
     8881 atctatgcgt ctagtttgtt aataagaaaa aaagcatatc acgactaatc gtgaagatgc
     8941 tttttttagt taaaatcaat ttagtttttc tttgatatca ttgaccattt cctgactggc
     9001 aataggtccg ttatatagcc aactagattc aggtccgaat tgcagtacat gattgtctgt
     9061 cactgcttta agattcttcc agcttggttc attgaacatg gcagcatctt tgtcactgtt
     9121 cacaaggatg atgtagtcag catctaattc agctagcttt tcagaggaaa cagcagacca
     9181 gtcagaagtg gcttttttgg agacctcttc cactagatca ggaacaccaa attccagatc
     9241 gtcgtatacg attcttccac ttgaccgatt tttgctgacc ataaaggctg agttgttggt
     9301 cacccacaac actgcagctg tcttgttctc gattttatct gctagttctt ctcgagtttt
     9361 cttgatggat ttttgataat cggaaatgat cttttctgcc tctttttctt ttgccaaagc
     9421 tttgccgaca tcttttagtt gttcttccca tgtgacatct gttccgtttt ttacaacata
     9481 agttggcgcg attttgctat attgttcgta tttcccgcct tcgacagtag cggaagaaga
     9541 aatcaacagc aaatcaggct caaagcttaa cactttctca taaggaaggt cataagaaat
     9601 cgttgggaca tcctttaaat catcttgcag ataatcttga atggaaccac tgccaacagt
     9661 ccactgggcg ataggttttt cccctagtgc aatcagatag tcttctaagt aactgccgat
     9721 gatccgtttg ggcgcgtttg gaatctctac tttatgtcca agtgtatctg tgactgtatg
     9781 agtactattg gatgaagtcg tcgaattggc agttgtagct gtttctttat ctgaagaggg
     9841 ggagcaagcg ctcagtactc cagccagcag caatatgcta gataatgtga atacttttgt
     9901 ttttaatttc atttctttcc tcctaacata attgagaatc tttctcattg gttattattc
     9961 ctgatatttc gaacgctgtc aaccgcttca tttggctata gatatgaaag tagcgcttga
    10021 cgaaatgttg aaacagcgtc ataattgaga atgattttca gcgaaaggat gggtgaaatg
    10081 acgagattaa gagcagctga cattgcagcc ggctacgaaa acaaaaaaat cattgaaaac
    10141 atgtctgtta cgattcctga agggaaaatc actagtttga ttgggccaaa tggaagtgga
    10201 aaatctactt tattgaaaag ttttacccgt atactacctg tgaaatcagg aaagatcatt
    10261 gtcaataact ctgatatctc tacatacagt tcaaaagaac ttgcaaaaaa aattgcatta
    10321 ttagcacaaa ctagtgaaca ccctacaggt atgacagtag aagaagtagt atcttacgga
    10381 cgataccctt atcaaaaact gttcagtggc atggacacgc aagatcatga agcaatcgag
    10441 tgggcgttgg atgctacagg tctagctgga tttcgtatgc gggatatcgc aacgctgtct
    10501 ggtggacaaa cccagcgtgt ctggatcgct atggcgcttg ctcaggaaac agatatcttg
    10561 atcttggatg aaccgacaac atttttagat ccggcacacc aattagagat cctacagtta
    10621 ttgactgaaa tcaatcaaat gaaacaaaca acgatcttga tgtcgattca tgacattaat
    10681 catgcttcac gtttttcaga ttatttatta gcaatgaaaa acggtaagtt gatcacagaa
    10741 ggtacacctg aagaagtgat cacaaaagag tgtatgaaaa aaatatttga gattgatgca
    10801 acgattgtca cgcttccaag aacaaataaa ccagtttttc taacctatga tttgttgcca
    10861 aaagagcagg aggatcaatt atgaggacta tgaagaaaaa tagactcctg cttttggtct
    10921 gttttgttct tttgattatt ttttttgttg ctctttcaaa tggcgcagcg actgtgggaa
    10981 aagcagattt ttggcaggcg ttgtttgatt ttgatagatc aaaacaaagt caccaaatca
    11041 tacgaaatat tcgtttgcct cgtgtggcgg gagcatttct tgtagggagt tgttttgcat
    11101 tgagcggtgc attgatgcaa ggagtgacaa gaaatccttt agcagattca ggcttactag
    11161 gaatcaacgc gggtgcttcg ttggcaatgg cccttagttt tgctttttgg cctaaagctt
    11221 ctgatttttc tgtgtttcta atgtcattgg caggttcttt tgctgtaact ttgctcgtat
    11281 ttggtttttt gcagttttcg aaaatgggca tgaatccttt acagctgatt ttagctggcg
    11341 tagctattag ttcttttttt actgctatca gccaagcact tacccaattc tttaatctgc
    11401 agcaggatct tgctttttgg tttgtaggcg gagctgccaa tatcacatgg aaacaattag
    11461 cagtattgtt tcctttatat atacttgctg ttttggtttc tttttcatta ggaaaagcaa
    11521 tatctttgat tcatttgagt gaaacacatg cattagctct tggaagtcat cctaaacgaa
    11581 cgcggttgat tgttttctgt ctagttgcag tgttagcagc cattgccgtt tcgttagtcg
    11641 gacctgtttc atttattggg ctgttggttc cgccagttgt tcgcggaatg gttggaacgg
    11701 actatcgtta tgttctacct gtctcttttt tagttggcgg tggattggtt atgttggcgg
    11761 attttacagc gaggatgatc aatccccctt ttgaaacacc ttttggatta gtcattgcat
    11821 tgattggcgt tccgttttta ctgatacaag taaggaggga acaacggtga aaaaaatata
    11881 ttggacgttc tatttcttgc tttttgtact tgtcatcctg tctataggta gtttaatgat
    11941 tggtacgcct tttatttacc tggatcagct ttttgccacg ttcataggga aagaatcatc
    12001 ttctttggcg ctgattgtta gagaatttcg agttcctcga ttactgatca gtttattagc
    12061 aggagcttgt cttggcgttt ctggttatat cttgcaagga gtaacaagaa atgaattggc
    12121 agattctagt atattgggca ttaatgccgg agcaggattt ttagtgatgc tttatttagg
    12181 tttcttttcg cactattcgc tgccgtttct attgctagtt gtagcctttc taggtggtgt
    12241 tttagctgct tgctgtgtct atcttgcggc ctatgatcga aatggctttt tgggtatgaa
    12301 tcgaatctta ttgtccggta ttgccgttaa tgccggcctt tctgcattaa cattgctatg
    12361 cacgatccaa ttatctaagg aaaattatgg atttgtgaat gcatggttag cgggatcaat
    12421 ctggggtgcg agctggcctt atgtttgggc attgcttcca tgggcggtta tcttaattcc
    12481 gctaggagga ctttatgcac agaggattgt attgctatca tttggtcaag aacgcgcgca
    12541 aggattaggc cttaacgtgg ctaaaagtca aaaaatcctt ttgttgttag ctgttgcttt
    12601 ggcaagcggt agtgtagcgg tgacaggtag tttatctttt gtaggactac tagctcctca
    12661 tgctgcgaag ctagtcgtac gtaaagaaaa taactggacc tttgttctga gcggtttgtt
    12721 cggttccatt tttctgctta gtgcagatat ggttgctaga gtgattctac taagtgggga
    12781 agtacctaca ggaattttga ttgccctttt tggtgcgcca tattttctgt atgcactttt
    12841 tatcagacaa aaacacgcgc tgaacagttg aaattcatta aaaaaggaag gccaatcatt
    12901 tctaggtctt ctttttattc tatttatgca tttatttgaa agttcgattg ctatttttct
    12961 ttttttccta taccatttta tgagagaagg aagggtgagt ttttggacca attgaaagta
    13021 agattacgcc ggaaaggaat cgaaaagctg aaaaatctgg ccaaaagtgg caagaaaaag
    13081 gaaaaagaac agcgaatcta taaacagcta ttcgccagcg agtactggaa gtcagcaaaa
    13141 gtgataggga cgactttatc gaatgaattt gaactggata cacagccggt tatccaacga
    13201 gcagaaaaag aacaaaagaa aatagttgta cctaaaactt tgccgaaacg tcagatggcg
    13261 ttttatgaaa tggatgaaca gtccgttctt gtacgttcga gttttggtgt tcttgagcca
    13321 caatcagaga agctctattt gccggagatg atcgatctcc tcattgtacc aggtattatc
    13381 tacaatagag ccggttatcg aatcggtttt ggcggtggtt attacgaccg gtatttaaat
    13441 aattttcata aaaaaacatg tagccttgtt tttcgtgaac aattgaatga acaatggcaa
    13501 ccggagagct ttgatcagaa gatccaacaa ttgtttattg actaaaatga aatgggaggt
    13561 tttcatgaat tatcaacagc aaataaaatt gcgtgcatgg ttaagacgac cgttatggac
    13621 ctatgctttt ttagggatac agacagcggt cttcctcatg atggaattat ttccgcgact
    13681 tgagatccct tattatgccg gaatgtatgg tccttatctt gttcacttca atgaatggtg
    13741 gcgtttagtg acaccaatct tcatccattt tggactgatg catttcgtaa tgaactcact
    13801 gatactgtat tttatggggc agcaaatcga ggcaatctat ggccattggc gttttttctt
    13861 gatttatatg ttcagcggga taatgggaaa tacagcaagc tttgctttta acgaagcgaa
    13921 tgttctgtct ggtggtgcaa gtacttcgat attcggtttg ttcggtgcgt tgtttatctt
    13981 agggtttcat tttaaacata acccagcgat ccagcagcta gtcagacatt ttcttttatt
    14041 tattgtgttg acatttgttt ttggtcttct ggatacctct gtagatgttt ggggacatgt
    14101 cggtgggcta attggcggat tagtgttagg gaatgttttg ggtctaccga aacaacagac
    14161 aagctattcg atacaccaaa ggattctttc tacactagtt tttgtatttc tttttgtaat
    14221 atgtatttta ctgggtttaa aaaaatatgg tttacttgta taatatgaag gaagtgctta
    14281 aagatggaga gcttatatga tgtacagcag ctgttcaaaa aatttggcat ctttatctat
    14341 gtgggtgcac gcatctatga cattgaatta atgactatcg aattgcgtaa tctgtatgat
    14401 agccgtttga ttgatcatga tacatacatg acagcgtggc gcatattaaa aagagagcac
    14461 cgaattgaag aaagccgaaa gaaaggaaat ttgtaatgga caagaagatt attgggattg
    14521 atttaggtgg aacaacagca aaatttgcaa ttttaacacc agaaggagag attcagcaaa
    14581 aatggagcat cgataccaat attttggatg atggtaagca tatcgttcct gaaatcattg
    14641 aatcaatcaa tcatcgtttg aatttatata atatgaaagc cgaagacttt atcggaatcg
    14701 gcatgggtac cccaggaagc gtggacagcg aagctggaac ggttattggt gcgtataact
    14761 taaactggac agaagttcaa tttgtgaaaa aactgatcga ggcaggaaca ggaatcaaat
    14821 tcgctatcga taatgacgcg aatgttgctg ctttaggtga acgatggaaa ggtgctggag
    14881 aaaacgatcc agacgttgta ttcgttactc taggaacagg tgttggcgga ggtatcgttg
    14941 ctggcggaaa tttgattcac ggcgtgagcg gagctggagg agaaatcgga catatcactg
    15001 tggatcctga agggttcgaa tgtacttgcg gtaaacgcgg atgtttagaa actgtatcta
    15061 gcgctacagg tgtggtacgc ctaggtcgtt tcttggcaga agaatacgca ggggattcaa
    15121 aactgaaagc aatgctagac aacggagaag aagtaacaag taaagatatc tttgaaatgg
    15181 ctcaagaaga cgatccgttt gcattgatgg ttgttgatcg cgtatgcttc tacttaggtt
    15241 tagcttgcgg aaacttgggg aatacattaa atccgtcaag tatcgtgtta ggtggaggag
    15301 tatcggcagc aggagaattt ttacgtagcc gtgtagagaa atattttaaa gaatttactt
    15361 tcccgcaagt aagagaatca acaaaaatca aattagcaga gcttggtaat gaagctggtg
    15421 tcattggtgc tgcctcatta gccttgaaat ttgcttaaaa aaacggaggc attacatggt
    15481 tttatgggta attaatatca ttttgctatt gattgtgctt gcaatcatcc tttgggaagt
    15541 ctatctacga gtaatggcca aacgttcagc aacgactttg acagaagaag aatttcgaga
    15601 aggaatgaga aaagcacaag taatcgatgt tcgcgaaaaa gatgtgtttg atgctgggca
    15661 tattttaggt gcaagaaaca tcccttacac tgttttgaaa gattcattag gatctattcg
    15721 aaaagaccag cctgtctata tttacgatca aaagaaaagt ttgagcatcc gtacagcaaa
    15781 taaattacgt aaagcaggtt atcaagagat ttatttactt aagggtggat atgacggatg
    15841 gtctggaaaa atcaaaagta aaaaagtata aaacagatga ttgtatgaca gctttaaaaa
    15901 ccgaatcaat cattagattt tgaccaagat cacatgaacg gcgcaatgga tagttgtgcc
    15961 gttcattttt tttattttgt gctattatct acatatataa gctaagcgaa aaggtagaaa
    16021 gaaggaaaca actatgatca aattaaaacg tgtttacctt gatgctgaaa aagaggatgg
    16081 ctatagaata ctcgtggata gattctggcc acgaggaatt tcaaaagaaa aagcgcagtt
    16141 agatctgtgg ttgaaagaaa ttgcacctag taatgaagca cgcaaaactt ttgaccatgt
    16201 accagaacga tttgcttcat ttgcaaagaa ataccagcaa gaattgattt tcgaagaaga
    16261 aaagaagcaa gctattttta aactcagtca acttatgaaa gaacatccag tcattacttt
    16321 tgtttatggt gcaaaaaatg aacatcagaa ccatgctgtt ttattgaaaa aatttatcga
    16381 aatggaggca tgcaaatgaa aatagggatc attggtgccg gacctagagg attaagtgta
    16441 gcagaaagga ttctccataa taatcaggac agacattctc ttgaactttt tcttttcgat
    16501 cccaatggtc ctggaggtcg agtttggcgg ttgaatcagc caccggagtt attaatgaat
    16561 tctgtttctc aacaagtgac gctttttaca gatgaaacat tgtccagtgg aggattggta
    16621 acacagggac ccaacttgtt tcaatggagt aaaggacctg ctacagatta tatcgaacag
    16681 acggtaacca aaaataagca actaattata gaagaaatca atcgtctgga aaaagatcag
    16741 caatctactc gatgtttata cggactctat caacgctggt ttttctcaaa gttgcaagaa
    16801 gaatttccag cttctattca gtttgtttat tctttagtaa aaaaagtaag caaaagaaaa
    16861 gatggttatc ttttacagac agatcagcaa agctattcta tcgatcagct tgttttagca
    16921 agcggtcact gggaaaatga tgagacagaa gaagaaagag tgtgggtaga ctacgcaaag
    16981 aaaaatgttt tactgtatca gcttccttct aatcctgcag atgtagatct ttcgaagata
    17041 ccgcctaaag aaaatgtctt tttaagaggt ctaggcttaa gtttttttga ttatgtcgga
    17101 ttgtttacag tatcaagagg agggcgcttc gagaacgaaa agggaaaact ggtctatcat
    17161 ccatcaggca aggaaccgat tgtatacagt ggatcaagaa gggggctccc ttattaccct
    17221 cgaggaagaa atcaaaagca aggcggagca atggcatggc cacggttact aacaaatgaa
    17281 aacctggagc aatggcatca gtcgggattt ttgactggcg aaacattttt tgactatctg
    17341 aaaaaagacg ttgagttgtt ttattacaag aaaatcatcg aagaatatca cttgccgatt
    17401 ccaaagaaaa attttgagca tgattttctc tccctctctt cagaggagtg tctcggaaag
    17461 catccagcac taatccctta tagatgggat tggtcgtatt tagaaactcc tcttgcctat
    17521 cagaatgagc ccttttcaga agctagccga atatttattg aagggcagat aaaagaagcg
    17581 gaaaaaggca attgcacagg agcatttgct tcaacatttg atgcattaaa agactggcgt
    17641 gatccaatcc ggcaggctat tgaatggcac gttttttctg ctaaggaata caaagaaata
    17701 ctatggggat ggtttactca tctaaatagc tttttaacga tcggtccgcc aatcattcgg
    17761 acgaaagaat tagcagcact gatagatgcg ggtatttttc atttgatcga accgccattt
    17821 gatattcagc aaaagcacaa ccgctatgtt atttctctac aagataaaga aatcagcagt
    17881 cgctatttga ttgaagctcg attgccacaa acaagctttt ctcgttcaag taatcctgtc
    17941 ataaaaaatt tgaaggaaaa caaacttgtt cgcccttttt cattttcaga taatacagga
    18001 agttatcatt cagaagctat agatgttgag cgaggtacga atcgcgtgat tgatgcttca
    18061 ggggaaatcc agtctgactt ttattgctat ggaatacctg ttgaaggtgt ggattggcta
    18121 actgcagcag tagctagacc ttatacagat ccatggaatc tgagacaggc agataaaata
    18181 gcacaactta tattgactga caaataaaaa tacgcatgat gacttatctg ttttttagaa
    18241 agtcttcatg cgtattttta aataattatt aacgagaaac gcgtttacgc attgcttttt
    18301 tacggttttc ttcgatcatt gcttcttttt cgtcaattgg atcgatcact gtttttttca
    18361 cagaagcaac caaaccagca acggcagcgg ctgttgccag acttcctact aatattccag
    18421 atacaaattt tttcattgaa tccacctcat ttattatttg ttatatctat tatggaacaa
    18481 aagagaaaaa aaggctagtt ttacgtttgt ttgtaaacct ttgcaaaaaa tccttgaaaa
    18541 tgtttactaa atgttttatt ataaatttac catatgaatt tacgaaattt tactttgttt
    18601 gttttcacca taaaagtaaa cttcgttttt taaattatat agaatcaaca aacacaattt
    18661 tactaatcaa aggagtgttt tttatgacaa ttttagtact aggcggagcc ggttatatcg
    18721 gttcgcacgc tgtagaccag ctagttcaaa aggggtatca agtagctgtg gtagataatt
    18781 tgctcacagg tcacaaacaa gcagtacatc cagatgctca tttttatgaa ggagacatcc
    18841 gggataaaga atttctacgt tccgtatttg aaaaggaacc gattgaagga gtaatccatt
    18901 ttgctgcaag ctctttagta ggagaatctg tcgaaaaacc attgatgtat ttcaacaaca
    18961 acgtatacgg tatgcaaatc ttacttgaag tcatgcacga gttcaacgtg aataaaatcg
    19021 tattctcttc tactgcagca acttatggag agccgaaaga gtctccaatc acagaagata
    19081 caccagctaa tcctaaaaat ccgtatggtg aaagtaaatt gatgatggaa aaaatgatga
    19141 agtggtgtga ccaagcatat ggcatgcgct atgtcgcttt gcgctacttc aatgtagccg
    19201 gagcaaaagc agatgcatct atcggagaag atcatacacc agaaacgcat cttgtcccaa
    19261 tcattttaca agtagctctt ggtcaaagaa aagccttggc tgtttatgga gacgattatg
    19321 atacaccaga tggaacatgt atcagagatt atgttcaagt agaagatttg attgctgcac
    19381 atattttagc tttggaatac ttgaaagaag gaaatgaaag caacttcttc aatttaggca
    19441 gcagcaaagg atactcagtc aaggaaatgc tagaagcagc tagagaagtg acaggaaaag
    19501 aaattccagc agaaatagca ccaagaagag ctggagatcc tagccgatta gtcgcttcaa
    19561 gtgaaaaagc gagagagatt ctgggctgga aacctgaata cacagatatc aaagcgatta
    19621 tcaaaacagc atgggattgg catgtcagcc atccaaatgg ttatgaagaa taggggaatg
    19681 agatatgtca atcagtcaaa cgatttgtga ttttgccaca cttgcgatcg aagctggcgg
    19741 atggatggaa atggaccgct tatatttaca gaatcgtctt ttagggatgg taggagaaga
    19801 tgctctagaa agcattgaag taagaccagt taaggaagaa tctgtagact tattggatca
    19861 gcttgtcgct aaggcaagag aaaatggtgt tctttcagaa ttgccagcag aacaagagat
    19921 ttttgaagcg caattaatgg attttctcac accgccacct tcagtcgtca atgcattctt
    19981 tgcacagcac tattcgaaaa gcccagagga agcaactgag tatttcttta atttaagtaa
    20041 gaaaaatgac tacatcaaaa caagagccat cgcaaaaaac atcaaatttc cggcagagtc
    20101 ggagtatggt gaactggaaa tcacaatcaa tttatctaag ccagaaaaag atccaaaaca
    20161 aatcgcagca gaacgcgagg cggtaaaagt agactatcct acctgcatgc tttgcatgga
    20221 aaacgaagga tatagaggtc gcttgaacta tccagcccgc accaatcacc ggattattcg
    20281 aatgaatcta gacggtgaaa gctggggatt ccaatattcc ccttatgctt attacaatga
    20341 acattcgatc attttatcag aacaacaccg cccgatgaaa atcacaaagg aaacatttgc
    20401 tagactgctt cggattactg aagtcttgcc tcattacttt gttggttcga atgctgactt
    20461 accaattgtt ggaggatcga ttctttctca tgatcattat caggcaggac gtcatgaatt
    20521 tcctatggca aaagcaccga tagaaaaact tatcaaacta gaagattatc cgcaagtcat
    20581 cgcaggagtc gtgaaatggc cgatgtctgt gatccgtttg caatcaacag agaaaaactt
    20641 gcttattgaa gcagctaact cagtattgga aaaatggaaa gcatattcgg atgaaacagt
    20701 atctatcaga gctttttcag cagatggtac accacaccat acgattacgc caattgcacg
    20761 aagaagggac aattactttg agttggacct tgtccttcga gacaacaatg tttcagaaga
    20821 acatcctgat gggatttttc atccacataa agatgtccaa catatcaaaa aggagaacat
    20881 tgggttgatc gaagtaatgg ggcttgctgt tttaccacct cgtttgaaac cagaactagt
    20941 agaagtagag catttcttat taggagaaga aaaccagatg gctgaatatc atcgtccgtg
    21001 ggcagaacaa ttaaaaaaag aacatcctga tttgacgaaa gatacggtca ccgatgtcgt
    21061 acaaaaatct gtaggtcagg tttttgcacg tgtactggaa gacgctggag tattcaagcg
    21121 agatgaaaaa ggacaggcag cgtttgaacg atttactgcg attttataaa cgtaaaaaag
    21181 gaggagagac aaatggcaac aattaaagac attgcgcagt tggcaggagt ttctcctgct
    21241 actgtttcaa gagttctcaa ctatgatcct gatctttccg ttggcttagc cacaaagcaa
    21301 aaaatttttg aagcagcaga acgcttaaat tatacgaaac atcgtaaaaa tgcagcaaat
    21361 actaagcaaa cgcttcgcct gatccagtgg tacgacgata cggaagagct tgaagatctt
    21421 tattatttat ctattcgcct aggaatcgaa aaaaaggcag aagaagcaaa cgttacttta
    21481 ttgaaagaaa cgtgggattc cattagtgat cttccggcag atggaacgat cgcactagga
    21541 aaattcgacg aagctcagtt attagaaatg aaaggatccc aaaatgcctt gcttttggta
    21601 gattctgacg gcacttctca aggaatcgac tctctagttg tcgactttaa gtcaagtgtt
    21661 caaaaagtca ttgaacactt tgtctcccat aaagcgcaac atatcgctat gcttgctgga
    21721 acagaatata cgaagaaaaa ccatcagcgg ctaaaagatc ccagaattat ggcatttcaa
    21781 caagttttgg cagaaaaagg ctacgacgaa ggtccaatta tcgaagcaga tttttctgtc
    21841 gagtcaggat atcaagcagt gaagcagtat ttaaaaacga atccgcatgt tcctgatgcg
    21901 ctttttgcag ctaatgatgc attagcgatt ggcgcactga aagcgattca agaaaaaggt
    21961 ttagtggtac cagaagatat ttctgtgatg ggcttcaatg atgtcagtgt agcgaaatat
    22021 gtaacgccct cgctttctac tgtaaaagtt tataccgaat ggatgggaga gctagcagtg
    22081 gagacgattc ttcaattaag taattccaaa gcaccggttt caagaaagat tattgtggaa
    22141 acagagttga ttattcgaga atcaacgaaa taaaagatgg aaaagctgtg ggaaaatgga
    22201 gtgataccgc agcttttttg tgtttcagga aggggcaaaa tttgcccgcc agcagataat
    22261 catgtattat tgtactagtt ttgcctttgg tattttcatc ctcagaataa aaaagtatgc
    22321 tacaatggaa ggcgagaatg tcatagcaga aaggatcaaa tatatgatta cattaggaat
    22381 agatactgca aaccaaactt tggcgatcgg tgtggtagaa gacgaacaaa ttcttggaca
    22441 aatacaaaca aatatcaaac gcaaccacag tgtaacactg atgcctgcaa tcgaccaatt
    22501 gtttgcagat cttcaaataa gtccaaaaga cattgaccga atcgcggttt ctgatggtcc
    22561 cggttcttat acagggcttc gtataggtgt aacgacagca aaaacgattg cttatacatt
    22621 agataaagag ctagtaggag tatctagtct gaaaaccatc gcggctaatt gcatcggtgt
    22681 ggataatatt attgtgccca tgtttgatgc tcgaagaaaa aatgtatacg ctggggcata
    22741 ccgctggaaa gaaaatagat tagaaactgt acttgaagat gtacatattt ctgcttctga
    22801 tttgttcaca caactacaaa agctgaatga agctatttat ttcgtcggga gtgattgtca
    22861 caaattcttc tctgaaataa aggaaatatt gcctagtgcg atgattaata cagttccagc
    22921 atgggatatt ccaagtggtg taactgtggc tcaattaggt gctttagttg aaccagttgc
    22981 agagaaacaa gcttttcttc ctcgctattt aaaacgagta gaagcagaag aaaaatggtt
    23041 ggagacgcac acacctggag acgaaagtta tgttgaaaaa atttagagcg tatgccagaa
    23101 gcttttttca agataaaatg atttatacag aaaaaacagt cgaacaaatc gatcgtcgtt
    23161 acgtactaag agaattgact acagaagata tcaaagagct gctggatgtc gaacgagaag
    23221 tctataatgg cgaattgcca tggacaaaaa gtgcctttat atcagaattg aagtcaccgc
    23281 ttcctcatct atatctaggt atctttgata atggaagaat gattggtttt atcggttcaa
    23341 gagcgttcgg tttagattgc catatcacga atattgccgt tcgaccggca tatcagcgta
    23401 aacgaatcgg ttcgctgctt attgacgaaa tcgagaactt tgctataatg aatcgctgtg
    23461 agacgatgtc attagaagtg cgtatgagta atcaagatgc acaaagactt tatcggaaat
    23521 tggggtttca agcaacaacg atcaaaaaaa gatattacac tgaaacaaaa gaagatgcgt
    23581 tggatatgat aaaactttta gaaaatgagt gagattagtt gatttgcaga aaaaaagatt
    23641 ttgatgaagc gtacttggca gaatgcgtat ggatgattag cgaaaatgct tatccacatg
    23701 gttcaccttg gacgaaaatg cagtttttgg cagacatcca acagcctcac tctgattatc
    23761 tgcttttagc tgaagataac cagatctgtg gctttattgg atactcgaaa gtaatagatg
    23821 aagtcgagat cacaaatatt gctgttgcag tttcagaaca aggaaaaggg catgcacggc
    23881 atttgttaca attactgatt acggaacaaa taaaagattc gctgcatgtt tttttagaag
    23941 tacgtctatc taatgaagca gcaagaaaac tttatgaatc agaaaagttt cgtatattag
    24001 gtaaacggaa atcatattat cgcaatccga cggaagatgc gatcattatg agcagaaagt
    24061 taaaaacgga gacgatgaaa tgaatgaaga attgattctg gcgattgaat caagttgtga
    24121 tgaaacgagt gtagcggtcg ttagaaatgg aacagagatc ttatctaaca tcgttgcttc
    24181 tcaaataaac agtcataaac gttttggtgg cgtagtacct gaagtagcta gccgccatca
    24241 cgtagaacaa atcaccttat gcttggaaga tgcactggta gaagctggtg tgtcggcaga
    24301 agatttatcg gcagtcgctg tcacttatgg accaggactt gtcggctcgt tgctgattgg
    24361 tatttctgca gctaaggctt ttgcttgggc acaccaattg ccgcttattc ctgtaaacca
    24421 tatggcaggg catatctatg cagcccgtct ggttaaacca ttccagtttc cattgatggc
    24481 acttcttgtt agcggaggac atacagaatt agtctatatg caagaagatg gatcatatga
    24541 aatcattggg gagacaagag atgacgcagc aggagaagct tatgacaaag ttggaagagt
    24601 attaggtctt tcttacccaa gcggaaaaga aatcgatcag ctagctcatc agggaaaaga
    24661 taattaccat tttccgcgag cgatgatcca tgaagataat tatgatttca gttttagcgg
    24721 attaaaaagt gcatttatca atttggtgca taatgcacaa cagcgtggag aagatctaga
    24781 caaaaatgat ttagcagcta gctttcaagc aagtgtgatc gatgtattga ttactaaaac
    24841 acttcgagct tgtcaaaatt atccagtcaa gcaactgatt atagctggag gtgtagcggc
    24901 caatcaaggg ttgcgtgaag gattgcagga tgctttggca actaaactcc ctgaggtaga
    24961 actagtgatt ccccctcttc gactttgtgg agataatgct gcaatgattg gagcagcagc
    25021 acatgtggaa atgcaaaaaa gaaattttgc tagctatcag ttgaatgctg atccaagctt
    25081 ggttttatct gaataaagag gttgtgaaaa agctgccctg catcaagtaa taagaacagc
    25141 ccaggaaaaa cggcttctca tgtttttgac ctggctgttc ttattaccgc gtatgcaagc
    25201 ttttgaacgc cgtttaatca agagttcgta agcctgtcgt ttaactctga ttcacaagga
    25261 acaatttcaa aaaacagctc ctcatgttta tgaacattat gacttgtgac cgaagagttg
    25321 acaggtacac accgtttaat cgaaataggg ctgtgacacg tttttgtcaa agccctattt
    25381 tttacatact tttaatcatt attgttattt tgctattttt tacagcttat ttatcattat
    25441 ccgttcctct gattgccctc actgagtaat cgtttattgt cgaggaatat cgaataatct
    25501 agatcggatg aggacaagac gcttcatcta gttaatctaa cagtattttt tgcaaacagt
    25561 gaatattaca taactgaaac acacatagaa aatctttgag tcttgtccag tgatctaaaa
    25621 ctgccggatc tttcagaagt tttagggagg aaaataagca gtgaccctga tatttatcag
    25681 ggtcactgct tatttttgtt cgcgttattc tctcatagct ggagtagtag ctgtcttaca
    25741 gaaagtaaaa cgctttttgt cataatctaa cagcccggaa tcacgtagtt gtttgattac
    25801 ttgtccagca gtttcacgtg tcgtgccgct attcactgct aattctttta aggtgatcgg
    25861 ataaggaatg gtgatatgac catcttttgt tggtacgccc aattcttctt tcaaaatgaa
    25921 taaattttgt tttacccggt caaaggcgct agaggtcaat ccgatttgga tacgcaattc
    25981 atgtatttca actactttag aaattttttg tatcatatag atcaactgtt cgggattttt
    26041 tcgtgctaat ttttcatagt aggaaacagg aaggtagaat gtttcaatat cagtcatcgc
    26101 ttgagctgta taagtgtagg tctcttctcc aaacattcct gacataggaa aaaggttatt
    26161 tgtattcaca tagtcatagt agtaataagt tgcactttca tcataacgtt ctaaacgaac
    26221 gagtcctttg gtcaagatat acaaccgttg tctgggatca ccatcgtcga aaaggatctg
    26281 tcctttttta taagaacgaa gaacagtatg ttccttgatc tgttggaact cttcatccga
    26341 gaaatgttca aaatcaggtt gatatctgag ttttgaaaag tgaaaatcga ttttattaac
    26401 acgcattaaa aagtcctctc cttattgttc actatattta ttgtcacttt ttttaaagaa
    26461 tttgtaaagt tttaacatac caacattaga aacaagtttt aatactttac aaatataatt
    26521 tgttattatg taaaaaatat acaatggtat tgaataattt gttttgaagc gaatgatttg
    26581 tgtataaaaa acaacaataa tacatatagt aaacgctaac aacgataata taatttattt
    26641 ttttaattta ttcaaaaaaa ttttttcaat gaataaatat ttttttgaaa gtgtatacag
    26701 aataaaaaat gaataaatta cgcttaaaaa tagaaaaacg tttaattatt taattatcga
    26761 atattaatgt gaggaatgtc tcattttgaa tgagacaaaa ttatgaaagt gattacaaaa
    26821 ggaggatatc ctatacatgt aatcaaaaag aaggaggcaa cacaacatgg ataaacctat
    26881 tcacgttttc tctgaaatag ggaaattaaa gacagtttta ctgaaacggc ctggacaaga
    26941 agtggaaaat ttgacaccag atattatgga tcgtctgttg ttcgatgata ttccatatct
    27001 tccgattgct caagaagaac atgacaactt tgcgaagaca ttgcaaaatg aaggcgtcga
    27061 gactctttac ttggaaaaat tagcggcaga agcgattgac gcaggcaatg tcaaagaaca
    27121 attcttgaat aaaatgttgg atgaatctca tattgcatcg aatgctgtaa gagagggtct
    27181 tcatgagttc cttctatcaa tggaaacgca agaaatggta gataaaatca tggctggggt
    27241 tcgtacaaaa gatatcgaag tacgttctag cagtctatat gatctgtcag cagacgatga
    27301 ctatccattt tacatggacc caatgccaaa cttgtacttt acacgcgacc cttccgcatc
    27361 aatgggaaat gggatgacag tcaataagat gacttttgaa gcacgtcgtc gtgaatcgat
    27421 gtttacagaa tatattttga aacatcatcc aagatttgca aataaaggaa tcgaagtatg
    27481 gttggatcgt gaaaatccag atcatatcga aggcggagac gaattgatct taagcgataa
    27541 agtagtagct gttgggattt ctcaacgaac taatgcgaaa gctttagaaa aattagcacg
    27601 ccacctattc gcaaaaaatt caggatttga aaaagtgttg gcaatcaaaa ttccgaacaa
    27661 ccgtgcaatg atgcatttgg ataccgtatt tacaatggta gatcacgata aattcactat
    27721 ccatccagca attcaaagta aagacggtaa gatggatgtc tttacaatcg aaccagatgg
    27781 tgatgatatc aagattactc attcagataa cttacacgaa acgatgaaag ctgctcttgg
    27841 attagatgat cttgtactga tcccaactgg taatggagat gagatcgttg cacctcgaga
    27901 acaatggaat gatggatcaa acacattggc aatcgctcca ggtgttgtag tcacttataa
    27961 ccgaaattat gtatcgaacg aattgcttcg tagctatggc atcaaagtgt tagaaatcaa
    28021 ttcaagtgaa ttgtcacgag gtcgtggtgg tccacgctgc atgagccaac cacttgtccg
    28081 tgaagacttg aagtaatttg tttcctgacg gcagtcttac tgtcagctgc cgtcgggatt
    28141 tcctctttaa tcttaaataa aaacaatcta aaggagaatg tttaatatga aagaatcagt
    28201 attccaagga agaagcttat tagcagaaaa agactttaca aaagaagaat tacaatattt
    28261 gatcgatttt tcagaacact tgaaagactt gaaaaaacgt ggtatcccac atcactatct
    28321 agaaggaaaa aatattgcgc ttttatttga aaaaacatct acacgtactc gttctgcatt
    28381 tactactgca gcgatcgatc taggtgcaca tcctgaatat ctaggtgcaa atgatatcca
    28441 attaggtaaa aaagaatcca cagaagatac agctaaagta ctaggacgta tgtttgacgg
    28501 aatcgaattc cgtggattca gtcaaaaaat ggtagaggaa ctagcagaat tctctggtgt
    28561 tccagtttgg aatggcttga ctgatgaatg gcatccaaca caaatgatcg ctgacttttt
    28621 aactatccaa gaaaactttg gaacagtaga aggtatcact gttgcttact gcggagatgg
    28681 tcgaaacaat atggctaact ctttattagt cacaggtgca attttaggag cgaatatgcg
    28741 tatcgttgca ccaaaagaat tacaacctga agaagaaatc gtcaaaatgg cagaaggctt
    28801 tgctgaaaaa tccggtgcac aattgatgat taccgacgat gttgataaag gtgtagacgg
    28861 agcagacgtc ctttattctg atgtatgggt atcaatgggt gaagaagata aattcgaaga
    28921 acgtatcaaa ttgttgaaac cttaccaaat caatatggaa atggtagaaa aaacacacaa
    28981 cacagatcgt ttgatcttct tgcactgctt gccagctttc catgatacaa acactgttta
    29041 cggtgaacaa atgaaagaac gctttggcat cactgaaatg gaagtaacag atgaagtctt
    29101 ccgcagcaaa tatgctcgtc aatttgacca agcagaaaat cgtatgcact caatcaaagc
    29161 gatcatggca gcaacattag gtaacttgtt tatccctcgc gtttaagcat aaccacattc
    29221 atctcacgaa aaaacgagtc agcattgagg gaaaatcaca aaacgctggc tcgttttgtt
    29281 atctagaaaa ttcggtagaa ctgaagaaag gacgaatgaa atggccaaac gaaaagtagt
    29341 tgtcgcttta gggggcaatg ccatcttgtc tacggatgca agtgcaaaag cccaacaaga
    29401 agcgttaatg gaaacagcaa agtatttagt gaaatttatc gaacaaggag atgaattgat
    29461 catctcccac ggaaatggtc cgcaagtcgg taacctattg attcagcagc aagctgctga
    29521 ttctgagaaa acaccggcaa tgcctttaga tacatgtgtt gcaatgacag aaggatctat
    29581 cggttactgg ttacaaaacg ccatgggcga agtactgaag gaaaaaggga tcgataaaga
    29641 tgtggtttct ttagtcactc aagttattgt ggatgaaaat gatccttcat tcaaaaatcc
    29701 aagtaaacca gtcggtccat tctacacgga agaagaagcc aaagaacaaa tgaatgctga
    29761 ctccactgtg acattcaaag aagatgctgg acgtggatgg agaaaagtag tcgcttcccc
    29821 taaacccatc tcgattaaag aagcacgtgt catcgaaacg ctggtcgatc aaggagttat
    29881 cacagtctct gttggtggcg gtgggattcc tgttgtagaa acagctactg gattagaagg
    29941 acgagaagcc gtaatcgata aagattttgc ttcagaaaaa ttagccgaaa tcatcgatgc
    30001 ggatttgctg atcgtattga caggagtaga caatgtgtat gtcaattacc aaaaaccaga
    30061 tcaaaagaaa ttagaaactg ttactgtttc agaaatgaaa caatacattg atgaaaagca
    30121 attcgctcca ggaagcatgc ttccgaaagt agaagcagct attgcatttg ttgaagcaaa
    30181 accaaacgct aaggcaatca tcacttcttt agaaaatatc gagaatcttt tagcttctga
    30241 agaaggaacg attatcgtag ctgattaatt tgttaagtct ttcgtattta cgaaatgatt
    30301 tatagctatc caggtggtat ttcttctcct ttaggccatc tggattttt
//
LOCUS       DAFEKH010000033        29103 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.034, whole genome shotgun sequence.
ACCESSION   DAFEKH010000033
VERSION     DAFEKH010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29103
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.034"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..1030)
                     /locus_tag="LP386_001686"
     CDS             complement(<1..1030)
                     /locus_tag="LP386_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL1918922.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1112..1801)
                     /locus_tag="LP386_001687"
     CDS             complement(1112..1801)
                     /locus_tag="LP386_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBL1918923.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="LP386_001688"
     CDS             complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="LP386_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HBL1918924.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2328..2831)
                     /locus_tag="LP386_001689"
     CDS             complement(2328..2831)
                     /locus_tag="LP386_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HBL1918925.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3035..3162)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="LP386_001690"
     CDS             complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="LP386_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HBL1918926.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="LP386_001691"
     CDS             complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="LP386_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HBL1918927.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4799..5467
                     /gene="sdaAB"
                     /locus_tag="LP386_001692"
     CDS             4799..5467
                     /gene="sdaAB"
                     /locus_tag="LP386_001692"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HBL1918928.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5480..6352
                     /gene="sdaAA"
                     /locus_tag="LP386_001693"
     CDS             5480..6352
                     /gene="sdaAA"
                     /locus_tag="LP386_001693"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HBL1918929.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6443..7462)
                     /locus_tag="LP386_001694"
     CDS             complement(6443..7462)
                     /locus_tag="LP386_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBL1918930.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7635..8540)
                     /locus_tag="LP386_001695"
     CDS             complement(7635..8540)
                     /locus_tag="LP386_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBL1918931.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="LP386_001696"
     CDS             complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="LP386_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HBL1918932.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9245..9415)
                     /gene="secE"
                     /locus_tag="LP386_001697"
     CDS             complement(9245..9415)
                     /gene="secE"
                     /locus_tag="LP386_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HBL1918933.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="LP386_001698"
     CDS             complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="LP386_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBL1918934.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9753..10397
                     /locus_tag="LP386_001699"
     CDS             9753..10397
                     /locus_tag="LP386_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBL1918935.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10453..10956)
                     /locus_tag="LP386_001700"
     CDS             complement(10453..10956)
                     /locus_tag="LP386_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBL1918936.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10969..11015)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11553..12518
                     /locus_tag="LP386_001701"
     CDS             11553..12518
                     /locus_tag="LP386_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBL1918937.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12617..13789)
                     /locus_tag="LP386_001702"
     CDS             complement(12617..13789)
                     /locus_tag="LP386_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1918938.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13776..14921)
                     /locus_tag="LP386_001703"
     CDS             complement(13776..14921)
                     /locus_tag="LP386_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1918939.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14935..15867)
                     /locus_tag="LP386_001704"
     CDS             complement(14935..15867)
                     /locus_tag="LP386_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1918940.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15984..17063
                     /locus_tag="LP386_001705"
     CDS             15984..17063
                     /locus_tag="LP386_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBL1918941.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17060..17689
                     /locus_tag="LP386_001706"
     CDS             17060..17689
                     /locus_tag="LP386_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1918942.1"
                     /translation="MITVVIIDDDPFVTKSLQTILESTKEIRVLGIGHCAKDALVLYE
                     THRPDVLLTDIRMPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYL
                     IKQNLQAIIPSVKSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKE
                     VAAGKNNKEIADALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(17799..18026)
                     /locus_tag="LP386_001707"
     CDS             complement(17799..18026)
                     /locus_tag="LP386_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL1918943.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18129..20717)
                     /locus_tag="LP386_001708"
     CDS             complement(18129..20717)
                     /locus_tag="LP386_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HBL1918944.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20737..21396)
                     /locus_tag="LP386_001709"
     CDS             complement(20737..21396)
                     /locus_tag="LP386_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBL1918945.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21445..21948)
                     /gene="trmL"
                     /locus_tag="LP386_001710"
     CDS             complement(21445..21948)
                     /gene="trmL"
                     /locus_tag="LP386_001710"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HBL1918946.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22169..23035)
                     /locus_tag="LP386_001711"
     CDS             complement(22169..23035)
                     /locus_tag="LP386_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBL1918947.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23144..23785
                     /locus_tag="LP386_001712"
     CDS             23144..23785
                     /locus_tag="LP386_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HBL1918948.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23847..25208)
                     /gene="mgtE"
                     /locus_tag="LP386_001713"
     CDS             complement(23847..25208)
                     /gene="mgtE"
                     /locus_tag="LP386_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HBL1918949.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25226..26125)
                     /locus_tag="LP386_001714"
     CDS             complement(25226..26125)
                     /locus_tag="LP386_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBL1918950.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26127..26924)
                     /locus_tag="LP386_001715"
     CDS             complement(26127..26924)
                     /locus_tag="LP386_001715"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HBL1918951.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26902..27606)
                     /locus_tag="LP386_001716"
     CDS             complement(26902..27606)
                     /locus_tag="LP386_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HBL1918952.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27737..28312
                     /locus_tag="LP386_001717"
     CDS             27737..28312
                     /locus_tag="LP386_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HBL1918953.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28430..>29103
                     /locus_tag="LP386_001718"
     CDS             28430..>29103
                     /locus_tag="LP386_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBL1918954.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLS"
BASE COUNT         8560 a         6169 c         5232 g         9142 t
ORIGIN      
        1 atacagtatt atttcggttg cttgctgctt cacctagccc ttgtactcgt gtttgattgg
       61 cgacttgacc aaattgattc ccgacgtcta ataaaataat agctaaaagc aaaatggcca
      121 aatggcttcc gccaaccaat aaagcaataa agcttattgt ttgcataaca agtcccatat
      181 acacgatttt tctttcagaa taagaatctg ccagtcgtcc cacgataggt gcagcaactg
      241 ctccagacaa accaaaaatc gctaatatcc ctgcttcgaa tgttccccaa ttgtaggcgg
      301 gactgctgat ataaaaaatc aacgtagacc aaaagatcga aaatgttcca aacatgaaaa
      361 atccactgac tgccgcttct cttaatagac gttgagaagc aactaaatgc ggcaaacttt
      421 taagtgaatc aaggtatgaa acagctgtac tactttgctg gacagaacgc ggcattttcc
      481 agtaaagcag aagtgtaaga attccgactg cacataaagc aaataaatag atcatccgcc
      541 aagaaaaaag actggcaaca ataccagata ccgtccgaga aagcaaaatc cccacgagta
      601 aaccgctaag caatgtaccc atgaccttcc ctcttgcttt tggtcccgct agtaccgcac
      661 cgtaaggaat gatgatttgc ggcacgatcg aaagtaatcc tattaaaaaa gaagcgcatg
      721 caaataacgt aaacgaaggc gcaaaaaaag cggccaacag agagacggca gataacgcta
      781 ccattcgaat gatcaatttt ggacgatcca ccacgtcccc taaaggaact aaaaacagta
      841 accctaacgc atagcctaat tgggtcaaca tcgtcaatat cccgactgca cttgtgctaa
      901 cagataaact agctgctact tttgttccaa tcggctggat gtaatacata ttggcaacaa
      961 caacgccaca agtgattgat aatagtaaaa taagcgaagt tgttaaaggt gttttttcat
     1021 tactcttcat tgatttcccc catttcctat cttagtttac aacttatgga aaagattgga
     1081 aatagaaaaa tacaactatt cgccacactt attatttgtg cttttgtttt ccttgttttt
     1141 tcttgcgatc tttataaatg aagacaacta accctactag cacagtaaca cttgcaacca
     1201 acgtgactgc agttttgtta tatccgtgaa acagagcttc tccaccacac gcatacaaca
     1261 cagacgaagg gatgactcca atcacgatcg acaatatgat ttgctgtaga ggcaatttca
     1321 tcgcatctgc agcaaaattg accatagaag atggaataac cggtatcata tagcctaaca
     1381 ttacacctat ttttggatgt ttcatttgtc ggattgcttg cacccaatga ttcgtttcgg
     1441 ttttcttatc taaaaatttt aagcgatgca taaggaaaat tgcagtgatg ttaccaagag
     1501 cattacccaa aatgttgatg atcgcacctg tcagtggtcc aaagctcaaa ccagcaatga
     1561 ctccaactac tgaagtagga atacctggaa cagcacacat caccgctgtc aatacgatca
     1621 agagtatcga tgcaaaagtc ccatgcgaac gaatatgtgc gagtagctct gccttactcg
     1681 ctctcggatt taaaaataat tggatgtctg tctgatattc taaatacaac cgatagccca
     1741 ctaccagtat cagaatgatt cccaacgaga tcaacatcaa tcggattatt ttctttttca
     1801 tatttcctcc tgaaaaaaat ctatattcat taaataatag tttaacataa aaacaaaaaa
     1861 gcaccgaaat ccaacatagg atctcagtgc ttttaaatag taaaaattat ttaacagtta
     1921 cagatgcgcc aacttcttca agtttagctt tcaattcttc agcttcttct ttagatacgc
     1981 cttctttaac tggtgcagga gcgccatcaa ctacagcttt agcttctttc aagcctaaac
     2041 cagttgcttc acgaactgct ttgataactt taactttttg gtctccagct gcagttaatt
     2101 ctacagtgaa ttctgtttgt tcttcagcag cagcagcgcc accagcagca gctacagcta
     2161 caggagcagc agcagatacg ccaaattctt cttcaatagc tttaactagg tcgttaagtt
     2221 ctaggatagt tgcttctttt aactcagcaa cgatgttttc aatgttcaat gccattataa
     2281 tttcctccgt ttaattgttc ttttttattt aatgctttat gcggcaatta agctgcatct
     2341 ccatcttctt tgtctgccac tgctttgaca gcgtaagcca cgttgcggac tggcgcttgt
     2401 agtacagata gcaacataga tagaagtcct tcgcgatttg gcaattttgc caatgctgtg
     2461 atttcttcca atgaagagac tttaccttcg atgataccgc ctttgatttc taatgctttt
     2521 gcttctttag caaattcgtc catgattttc gctggtgcga ctacatcttc gttactgaat
     2581 gcaacagctg taggtccagt gaatacttcg tccatgcctt caaggccagc ttttttagct
     2641 gcacgtgaaa gaatagaatt tttgataact ttcatttcta cgttagcatc acgaagttgt
     2701 ttacgtaaac gtgttacttc atcaactgtt aatccgcggt agtcaacgac tactactgat
     2761 gcagctgctg taaatttttc gcttacttca tcaacgattg ctgctttttt tgcgataatt
     2821 gcttcactca tttttgagtt tcacctcctg aattttgatg gaagagtttt ttgcactgaa
     2881 aaggcaagtc acttttatag ttactttgct caaccagtat tattcatcac ctattcactt
     2941 cgttcatagt gattctactc gctttgctcg aaaggaaact cctttcgctt tgctcaacca
     3001 gtattgttca tcatctcttc acttcgttca tagtgattca caataaaaaa ctctatgcca
     3061 ccgcagacat agagggacta ttgaatatat tcaataaacg tcctcggtag gaaattaagg
     3121 cttgatgcca cctactgtct tcggtacaag ttaattatta acctcaacta gcttagcatg
     3181 ctaaactagt tgagtcaaga attatttttc agttggatca atcaacattc taatatttaa
     3241 ttagaaagaa gcttggtcaa catggatacc aggtccaaat gttgttgtga tcgttacatt
     3301 tttcatgtat tgacctttag ctgctgatgg tttagctttt agcaatacat catggattgc
     3361 tgcaaagttt tcaactaatt tttcatcgtc aaatgaaact tttccgattg gtacatggat
     3421 atttccagct ttgtccacac ggtaagttac tttaccagct ttcacttcgt ttactgcttt
     3481 tgttacgtcc attgtaactg taccagtttt agggtttggc attaagcctt ttggtcctaa
     3541 tactcgtcct agacgaccta cagtagccat catatcaggt gttgcaacaa ctacatcaaa
     3601 gtcaaaccat ccgttttgga ttttttgaac catgtcgtcg tcacctacga aatctgcacc
     3661 agctgcttca gcttcttttg ctttgtctcc tttagcaaaa actaaaacag tttgtgtttt
     3721 accagttccg tttggtaata caacagcacc acggatttgt tggtctgctt ttttagggtc
     3781 tacgttcaaa cggtatgcaa cttcaactgt tgcatcaaat tttgcaatgt ttgtttcttt
     3841 tgctaaagct actgcttcgg caacaggata aactttactt gaatcaactt tttttaatgc
     3901 atcttgcatt tttttgctct ttttagccat tttggttcct ccttgattgt ggttataacg
     3961 gttgtacctc ccacgtgttc tatatctttc aatatagagc caactgagaa gctgctgtct
     4021 tagggtgtat agattattct acagtgatcc ccatgcttcg tgcagttcct tcaaccatgc
     4081 gcattgctgc ttcaacgtta gctgcgttta ggtcttccat ttttaattca gcgatttctc
     4141 ttacttgatc gctagaaact ttcgcaactt tatttttgtt tggttcgcct gaaccttttt
     4201 cgattttagc tgcttttttc aatagaacag cagctggcgg tgtttttgta acgaatgtga
     4261 atgaacggtc ttcgtataca gaaataacaa ccggaatgat caaacctgct tgatcagctg
     4321 tacgagcgtt gaattctttt gtgaatccca tgatattgat acccgcttga cctagtgcag
     4381 gacctactgg tggagctgga gttgctttac ctgcaggaat ttgcaattta acgatttttt
     4441 ctactttctt tgccacgaga catacctcct taagtccgtg atgtggttaa ttggagatgc
     4501 atatttctcc tcccacgttt tatctgatct gaaaaaatcc agacaaataa tgtgcaaaac
     4561 aatgcacact ggtacagtat agcaaattta tttgtttttt caagattttt ttctgctatt
     4621 tttacatttt gcttgaataa acgctaaatt tattctaaaa aaacaacaat ttttcgttct
     4681 catttcttct tttatgttac acttgcgcta gcatggttca acagatgaaa gcaaacaata
     4741 acacggtttt ttagaccctt gtacaaagat tcctacataa caaaatgagg tggagaaaat
     4801 gaaagattta aggtatagaa gtgtctttga tattattgga cctgtgatga ttggtccaag
     4861 tagctctcac actgccggag ctgctagaat cgggaaaatc atacgtagta tatttggcga
     4921 acagcctgat tctgtagata tttatctata tgaatcattt gcaaaaacct atcgggggca
     4981 cggaacagat attgcattag ttggcggcct gttagggatg gaacccgatg atgaacgttt
     5041 agctgattct ttgaaattgg catatgaagc cggtatggaa gtcttgtttg ttcctaagag
     5101 tgaaaaagcc gaacatccaa actctgtaaa gatgcttcta aaaaaaggaa cacgaaagct
     5161 ttcagtcact ggcatttcga tcggcggtgg caatatccag atttctgaat tgaatggatt
     5221 caaaatttct ttaagcatgg gtactcctac cttgatcgtt gtccaccaag atgttccagg
     5281 tatgattgct aaagtgacta gtatactttc tgagaccaat acgaatatcg gcactatgac
     5341 agtgacacgg gaatcaaaag gtgaaaatgc cattatgata attgaagtag atgatcctca
     5401 agtagaagaa acggtaaaaa gactcaaaca gctgccaaat atcgacagcg taaattattt
     5461 cgattaagga gctaaaaaaa tgtttttatc gattgaagaa ttagtagatc aagcaaaagc
     5521 ttatccaagt gtagcagaat tgatgattgc agttgaaatg gaaatgagtg gccgttcccg
     5581 tagtcacatc atcgagatca tggaaaaaaa cctctcagta atggaacaat caatcaacga
     5641 gggaaaagaa ggtgttacct ccgtcacagg aattaccggt ggtgatgcaa aaaaattaga
     5701 tgattattta aatgaggcag actttttaag tggagaaaca atcttaaaag ctgtacgcaa
     5761 tgctgtagct gttaatgaag tcaatgcaaa aatggggttg atttgtgcta caccgactgc
     5821 cggaagcgcg ggtgttgttc ctggtgtgct gatggctgtc cgagatcggc ttgatttgac
     5881 acatgaacag caattggaat tcttatttac cgctggcgct ttcgggttag tcatcgcaaa
     5941 caacgcttct atcagtggtg cagaaggggg atgtcaagca gaagttggtt ctgcaagtgc
     6001 aatggcagca gcagctttgg tttgtgcaaa aaatgggact cctcatcaag cagcacaagc
     6061 agtagccatt acattgaaaa atatgatggg actgatttgc gatcccgttg caggcttagt
     6121 tgaagtcccg tgtgtcaaac gtaatgcttt aggctcttct caagctttta tctctgctga
     6181 tatggcatta gcgggtatcg aaagtgtcat tccgccggat gaagtcgttg ctgcaatgta
     6241 ccaagtcgga cgtcaaatgc cgtcgatttt caaagaaaca gcagaaggtg gcttagctgt
     6301 tacgccaact gctaaacgac ttgcggaaga gattttaaat aagagggcgt gataaagctc
     6361 cttaatttcg agtattaaga gattagttat cttcataaca aaaaacgaag agaggactaa
     6421 ttgcccttct cttcgttttt tattaatcca tcaatttcgt attttttact tcatcgatcg
     6481 tttttgttcc tgcaagttgc atcgtgatcg acaattcttt gttcaggtgt tcaaaaacag
     6541 atgttactcc ttctgcccca cctagattca acccataaat cactggtcgg ccaatcgcaa
     6601 ctaagtcagc accacttgcc agagctttga agacatgctc tcctcgacgg acaccagagt
     6661 cgaaaatcac tggtacacgt ttgttgacta cttcggcaat ttttggcaat acttcaaagg
     6721 acgcaggacc tccatctaat tgacgtccac catgattgga tacccagata ccatctgccc
     6781 ctgcagagat agcgattact gcatcttctg gcgattgtat tccttttacg ataactggaa
     6841 gatgggtgat ttctttgatt gttttgatgt catctggtgt caagccttgt tttgcagctg
     6901 cataaatttc tgcgattcct tttccttcgc cattaccact tgcactttgt tcgctatacg
     6961 cagctaagtt aggcattggt aatggaaatt ggaattgatt gatgacgtct tcttcacggt
     7021 aaccaccgag cgttgaatct gccgttaaaa tgatagcttt agcccctgct tctactgctt
     7081 tgttcaaaat gaactcattg aatctgtcgt ctttactcat atataattgg aaaaactgcg
     7141 gtgcgcctgg cgctgcatcg gctgcgtctt tgattgtcgt atttgcataa gtgctgatgg
     7201 aaaagattga tccagcagca gctactcctt tagctgtatc agcttcccct ttttcatgtg
     7261 ccaatccttg ggccgctgat ggcgcttgga taatcggtgt atctaattca attccgaaaa
     7321 cagatgtatg caaatcggct gagtcgattc cgcgtaatat ccgtggcatg attttctttg
     7381 tattaaaaga agtcgtattt tctttcatcg tccactcatc ttcagaacca ccgcgaatat
     7441 agccaaaagc tcctgcttcc atgcgctctt ttacacgacc ttctagttag gcaatgttta
     7501 caatatcgat tggatgttct tcattacttg tatgataagt catagtagat ccttctttca
     7561 tcttcttgat tacatataaa tcatactaaa cttacaaaaa gtaagcaaac atttactctc
     7621 agatactttt atcgctattc tttccaaata aatcgactta caagctgatc tacttcttgg
     7681 ttttcatgaa gcatactatg agaggcattt tcacctgtca ctactttttc ctctatttca
     7741 tttccgcgtt gcttcaacaa cgcatagacc gctaatgcac tgtttaacgg tactgttcca
     7801 tcactcaagt ctgtttcatc tagttgacca gcaatcaaga aaaatcgagt ggttatagga
     7861 atattaccga tcatttgctg gtaatcttga tagcggttag aaacgacagc aggccccttt
     7921 gctaactcat ctgtcagaga ctgcgcacta tcatcgacaa aatcattaaa aggcgcgcca
     7981 attgctgtta atgtctgaac ttgtggcaat gacgtatcct gtccatacgt tcctaaatag
     8041 cgtagtgcac taactcctcc catggaatgc cccactatgt tgactttatc tatgccgtag
     8101 ttttctttca gatacaaaag acaagttttg atccattctg cttgattcca ctcgttattt
     8161 ttattatctt caaacaatac ttggaccatc ggattgtctg cttttccaga caaatctcct
     8221 gttgcttgta tttgtccatc tgttcctact gttaaaacca attcttttac tgcttgctga
     8281 tttttttcca aacgccgcaa catcccttta aaggaatttt ctgtcccgct gtagccgtgg
     8341 aaaaaaagtg ttggaatagt ggttttttct atcactttac tggattctgc cgttttttct
     8401 ttatcagaaa cttcagtagt atttatcttc gtcgtctggc aaccacttaa cgcaaacaaa
     8461 ctgataagga ctaaagctgc tgcagttgca cgtttgcata aatttttgat tggttctgtc
     8521 atacacctct tcctttccat atagaaaaaa gaaagacttg aaaggccaat catatgatcg
     8581 acatttcaag tctctttatt aatcgatttt atctacttga tcgaaatcaa gttctgtact
     8641 ggtttcacgt ccaaacatat cgatgttgac tttcaatttt tctttttctc cgtcaacttc
     8701 tgttacttgt ccttctaatc cagcaaatgc gccttcgatg attttcacga cttcgccaac
     8761 ttctacttct agatcatttt gtcgcaggct cataccgata gaacgcaaga tatgattgac
     8821 ttcttctgga agtaatggtg ctggtttgct tccggctccg tgtgaaccaa cgaatcctgt
     8881 cacaccaggt gtgttgcgga caacatacca tgaagcgtct gtcatgatca tttcaacaag
     8941 tacgtatcct gggaatgttt tatgaacgat ttctttttct ttcccatttt tgacttcagt
     9001 ttctttttct tcaggaacaa cgacacggaa aataaagtcg gccattttca tactttgcgc
     9061 acgagattcg atatttgctt ttactttgtt ttcatatcct gaatatgtat gcaagacata
     9121 ccagtttttt tcaaaagatt ccattgaagg ctcctcattt cattgtaaaa taaaaaaacc
     9181 tcagtacacc cgaagttttt ctttcgcttc attatagcac taaaagtacg ttgtggctag
     9241 cgagttattt taaaatccag ccaaataagc tttggatggc tgtatccatt acgtaaaaca
     9301 tcaatccgaa aataatagaa gtttcgatga ctactaacgt atctttacgg agttgttttc
     9361 tgcttggcca agttacttgt ttgatttcat cttttacgct ttttagaaat ttcatgagac
     9421 aacctccctt gctactgttt atttcgtttc tttatgtaat gtatattgat tacaatattt
     9481 acaaaactta ttgatttcca aacgttcgcc gctttttcct tcactgactg attttgtgta
     9541 gttgcgagac ccacaaacgg aacaagcgag tgctgctttt ttctttgcca tttacttctg
     9601 cccccttgct gagaatcaga cttatacttc ataacagtat cacgtaactt tttacttgtc
     9661 aatttgtgaa ataaactatc tattgttttg gataaaatta tgatatgatt aatttgaaat
     9721 taagctaaaa tgagacaatt ggaggtatag cgatgctatt aaaaacactt gtatataaga
     9781 aaaaagatct gacaaccgtt acagagacta gtacattaga agaagcatta aaaattttag
     9841 aaacttccgg ataccgttgt gtgccgatct tagattcttc aggtaatatt ttccgtggaa
     9901 acatttacaa aatgcatatc tatcgtcata aagcaaatgg cggtgatatg acgcttcctg
     9961 tcactcatct tttgaaaaac gctacaaagt tcatttacct ggatacttct ttcttcaaag
    10021 tattctttac gatcaaagag cttccttata ttgctgtcct tgacagtgaa aatcattttt
    10081 atggtatttt gacacatagt acgttgctta atatgctctc tcaatcttgg agcgtagaac
    10141 aaggaagcta tgtactgaca attgcttcca caggaaagca aggagatttg gctgctattg
    10201 caaaaatcat ttcaaaacac agcagcattg ccagctgtat tactcttgat atcgaaaaag
    10261 acgaatacat tcgacgtaca ttgatcacgc taccggctaa cactgaagcg aaagtatgtg
    10321 aaacgatcgt caaccactta gagaaaaaga attataaagt ggtagaaatt gaaaatttgc
    10381 aaaaccaaga agcataatca aaaagcgaaa aaagaaaaca gcttatctgc tttctttttt
    10441 cgctttttat aattagacac gcttttcaaa atcaagcgcg cgatctaaat aatacatcaa
    10501 tggtgctgaa acagccatga cgataaactc acttaatgca agcgtgccat aggttgtcca
    10561 aaatgcttgg ccacctgttg gaactaacat ataagcaatc agtcccatgc tgatggtaaa
    10621 gaagatcgtg ttcaatacta aacgcatctt tacatttttc actttgtttt gcaataaagc
    10681 tgtcaggcct aaagaaagca atgtttggcc gccaccaaaa accacatcca tgataccaaa
    10741 accaaagaag gcattataga cgatgacccc gcctaaaact ccccaaagca atttacggtt
    10801 aaagacaact aaatgattca aactttctga aatacgaaac tggatcggcc ctgaggatac
    10861 aggcgcaact aaaatagtta acgctagata aagagccatg atgatgccat ttacaacgat
    10921 tacggataac cgttgtctgc ttttcgtttt ttgcattttc tctcctcttt tctcctagtt
    10981 tttttaacgc gggatggttg atgaaccgcg gttatgtgaa acaaacaata attataacag
    11041 acttttcatt tatttcaatc cgtcttatct gcttttaaaa aagcaaaagc ttaaacaatg
    11101 taaacgtttg ctaaaaatcg tgggatatgg tataaagtaa gtgtaagggg tcataagaat
    11161 tcccagtaaa gcagacgaag taggatctgc aagaacagaa ttgttgtgaa acttaaataa
    11221 ataaaaaagg atgtgggaat ttgagcaacc tcttactaga gaacggtcta gcaagcagct
    11281 gaagatctaa gtggacatgc cgaaccttgg aacttctcct tacgtaagta atggatcatg
    11341 cgcttgctag gcttttttgt gtttttcggt cttcggacct ttttcatttt cctagacttc
    11401 tgctataata accaagaatt aattttgtaa cagatttttt tgaaaaaaca agtttctttc
    11461 attcaaaaaa tagaaaaagc ttgctaatta ttggttaacc agcaaacagg agtattaaaa
    11521 tatcttgttt tattgaatag caggaggaaa tcatgaaatt ccattatcat atattgatca
    11581 atccatcggc aggcagcgga aatggctata aagtagcaga aagaatttta ccggtattaa
    11641 aaaataagca tattgactat acacttcatt atagtgaata caaaggacac gatgctgaga
    11701 ttgctgaaac tttggcaaaa gaaacattga ttccttggat agaagaagaa cagaaaacaa
    11761 tcgatacttt cccccttttg atcatcgtag gaggtgacgg caccttacat caggtacttg
    11821 atactttcta tcagatggaa gtagaattcc cagttgctta tattccagca ggttctggaa
    11881 atgattttgc tcgaggggca ggccttccaa aaaatcccaa aaaaggactt cagctgattt
    11941 tagcagctca atcaccagaa aaagtccaca taatggctta tgaagaaaaa ataagtgaaa
    12001 aaaaaggaat agctgttaat aatttcggta taggattaga tgcagctatc gtccatgcga
    12061 caaatcattc ttccacaaaa aagcgattga acaaatacaa cttaggatca ttttcgtatt
    12121 tattctctat tctccgtgct ttattcactc aaaaaggatt tccaattctg gtagatgcag
    12181 gaggaaaaca attaagtttt tcaaacgcat ttttatgtac agcaacgaag catccttttt
    12241 ttggcggagg aatcgcgatt gttccaactg ctgatgcgtc taaaccagtc attgattttg
    12301 tcgtggtcga acgaatcaat ttctttaaaa tcttgtggct cattctttta cttatacaga
    12361 aaaaacaatt gaaatcgaaa tatttccatc actacacaac aaacagatta cgtatcgttt
    12421 caacaacacc gcaacatggt caagaagatg gagaagaaat ggaaaaacga ccttttgata
    12481 tcacaataac cacaactaaa cagttgtttt ggtgttaata aaagaggttt tgtcagaagc
    12541 tacatctgga acaccgttta ttcggaaaaa aggactgtga cacgactttt gtcacagtcc
    12601 tttttttact atgcagttaa ttctttgccc aattgggttg ccatcgatag tttctttctt
    12661 tacccaaaat aaattggatc attgaaaaca ccgcagcaaa agcaactaag acacaaccat
    12721 tgaaccaaaa agattctgca aatgtttgat tgtaactgag tgtttcactg atcaagttat
    12781 tattttgaac aaaccaatat gttggtgtga atgccgctat tttgctaacc atttctggca
    12841 agtattctgc tggtacaaac accccaccga taaagcaact gcctgtgata aaaatatctt
    12901 tgatcccacc gctggtttct gagtttttta ccaatgaagt gatacaagcc gaaaagctaa
    12961 tgatcggcaa taaaaacaag aaagtattta aaatatgata ccataccgtt atatcccacg
    13021 aggtgtggat cactaacaga accattagaa gtaagaagcc actgaacaac agcagcgagt
    13081 aactaatcaa actaaaggtt actttgcgat tcaagtttcg tttggtaatg ggcgcactct
    13141 ggtttcgttt actgatctct ttgcgattaa acgctagatt gatgacgctg aaaccgctaa
    13201 aaatggatag aaacaaccca taagacaaga aattaaaggt tgtgcccgtc aacagctttt
    13261 tcatccgctg actatatccc gcacttagct caacttctcc agtaaccgag agtgccattt
    13321 gtgtctgttc catagctgca tcgattgttt tatcttcttc ttgaaacaga atcagtgttt
    13381 gcaaaaaggt gttcacttgc tgtgtaacaa ctgttttaga aaaggcatct gggcgactct
    13441 gtatcttgat cgtcgccatc tttcctactt cgacttgttc ggtaaagtct gcaggcagat
    13501 gtaagataat gtttacacga ttaaaataaa gagcatcatc gatttctttt tgtgaggttc
    13561 catccaatgt aacgactgtt tccttgtcat tcaaatattt acgaaggcca tcgactacag
    13621 gcgactcttc ttcactaatc aaggcgattt tcgcatcttg cagagaggta ttttcaacat
    13681 caatattttg cgcaaaaaag aatgtggcaa caacagtgat aattacacct atcagtaaat
    13741 tcgatttatt tgctttaagc aatgtccaaa tcgttttata aagcgtcata acgcacccct
    13801 ctttccatcc aagcatttcc taacgcaaaa aggaaaataa atccgatcaa ccatagaaga
    13861 ttggtataaa aactagccaa atcagtgtag aaataaagtt tatacaaact ttcgctgatc
    13921 aagttgacga gatttaattg accaacaatc ggaatatgaa gatcaatcca atacttcact
    13981 tgttccgacc ccatcatacc agcaaaaaag ctcatcgcaa tcgtcactga aatcaagatg
    14041 ctatcctttt gcaccagatt catttttggt atcaaattac caaccaatgt acctaacaaa
    14101 atcgcacaca acgaccccag agcggtaaca atcatcaacc attgccaacg ttcaccaaag
    14161 tctacttgat agataaaacg aaagacagct aacataatat aaatctctgt caaaacaatc
    14221 gtaaagcttg ctgccaaatt agcgattgaa actaacgatt gctttctagg aatcaaggac
    14281 aagcgaatac catttgacga ttgatttgct tgctgatcct gtacattgcg gaccccccac
    14341 atcgtcccgt agagaatcgc cattccaatc agagtgaaga aataaaaact tttgaaactc
    14401 atattacgac ctgcatgaac ttcttgaaaa gatacttctt gttcaaaaac agtcatgatg
    14461 ggcgcgagat caacgttctc cacttctgcc actttactcg aaattatacc aatacgctgt
    14521 aaaaattgat ccatgacgtt tttcatcaac gtctgactca ttcctgcttg acccacatgg
    14581 agcgaaacag atgaaccatc aatgagataa aaaccagcca aatcatctgc atttagcttt
    14641 tcattcgctt ctacttccga tagttcctgt acttcaaata atggtttatc attgacttcg
    14701 acttgttcta agactgtggt aaaattttcc gaaagcgctg tttgatccgc tttgattaca
    14761 attccagtat taatcgtttc aagattgcca ccttgatcaa tctcgccaaa ggccgccata
    14821 aacatcaatc ctaaaagaat tggaaaggcc aatgtccaaa acaacatgga tttatttcgc
    14881 agcagtattt ttgtgcgata tttataaaaa tgccaaaaca ttatttcccc tcctctagtc
    14941 tctcaaatcc ttgccagtaa tctctaaaaa gacatcattc aaggacgctt ctttggttgc
    15001 tatttttccg taactgatct tttcttcttg taagattgta agaatcggca acaatactgt
    15061 atttagttca gtagttgtta cttggagctg acctttttta taagcgattc catcagaagc
    15121 tattgttcgc tgaatcgctg acaacacatt ttctgggagt aatgggatgt cgatcgtcaa
    15181 acgatccgcc gtccgtacca tatcttttag agattctttg gttcctttag caatcacctg
    15241 tccttgatcc atgatcacga tctggtcgca aagaatttct acttcttcca tgtaatgtgt
    15301 tgtatagaca atggttgctc cttgtcgatt cagctccttg atactttcta aaattttatt
    15361 ccgactttgg gggtctacag ctactgtcgg ctcatctaaa aaaattaacc gcggcttgtg
    15421 ggcaatccca catgcgatgt tcaaccgacg tttcaagcca ccactaagtt ctcctggacg
    15481 aaacgaaaca tatttttcta atcccactaa ttgaatcacc tcttcaatca aggctttcct
    15541 tttctctttt tcggaaacat ataaaccgca aaaataatcg atattttctt gcacacttag
    15601 ttcgtcaaag accgcaacgt cttgaggaac gaccccaatc attgccttga cagcataatt
    15661 ttcaggagtc attgttgtcc cgaacaattt aatggttcct ttgtcataat ttaacaaaga
    15721 aagcatacag ttgatggcag tcgatttccc actgccgttt ggacctaaca gacctaagac
    15781 ttctccttct tgtacttgca gatcaaaatg attcaatgct acaaaatctc catagcgttt
    15841 gactaattta tcaatttcga taatcatcat gaaaaactcc ttccaaattt cttgttgatc
    15901 tgactataat aaagtgcaag aaaagaaact agtgacgatt ggctaaacca cacatgacat
    15961 ttgtcacaat gaaggagtct gctatgcata aatctcggct actcaacgaa actagctttc
    16021 tactggttat ctcattgctt ttgctggtaa gtcaaggatt cgttgctatg caagttatct
    16081 atttattgat cgccgtttta ttcactggtg tcagttattt actgcctaca aagccaaatt
    16141 ggattttcca agttattcta tttcttttat gtgccttttt acctgatctt gtcctgtttc
    16201 tgccagcgac gatgcgagtg atcgcccctg aagaaagcca ccttgattac ttgtttttgt
    16261 taggtttttt gttgatttcg acggttggta atcatccccc catcaaggtc gcctttgtcg
    16321 taattttgct gtttttttcc ttttacttac gaaaaaaaga tcaacgaacg accgatcttg
    16381 agaaaaagta cattgtctcc aaagatactc attgggaaaa acaacaagag ttatcggaac
    16441 aaaataaagc attggccctg tcacaagaaa cacaattagc cttgcaaatt gtggaagaac
    16501 ggaaccgaat tgcccgagac atccatgaca atgtcggtca tctgctgtca agtgcgattt
    16561 tacaaattgg tgcgcttgaa atgatcaatc aagaaccaaa actaaaagaa ccattagaaa
    16621 atttaagtgc caccgttcac actgggatgg atcggattcg tcaaagtgtc catgacctcc
    16681 atgagacatc gatctctttt caacactcct tagagtttct gatcgctgat tttccttctt
    16741 ctgttacgat tgaaggaaac ttgtttgaag gattgaatga aacgcagcaa aactgcttct
    16801 taatggtcat caaagaagcc ttaaccaaca gtatcaaaca tagtcatgcc aaaaccgttg
    16861 ttttacattt tcgaacgttg ccggcctttt atcgcttgca aatcacgaat gatggcacca
    16921 gcccacaaaa aaattctgct cccggtattg gtttgaaaac gatgcgtcaa cgtgttcaag
    16981 aacaaaaggg acaagtccat attttccaag aaaaccagca atttcagtta acgatcattt
    17041 taccaaggga gggacaccaa tgataacagt agtcattatt gatgatgatc catttgtgac
    17101 gaaatcgtta caaaccattt tagaaagcac gaaagagatc cgtgtgttag gcattggtca
    17161 ttgtgccaag gatgcgctag tcttatacga aacccatcgt cccgatgttt tgctgacgga
    17221 catccgcatg cctaaacaaa cgggcatcga tgctgccaaa gaaattttgg ctaaatttcc
    17281 caaagccatc cttttgcttt tgacgacatt caaagatgaa gaatacatcc gcgaagcatt
    17341 ttccatcggt gtcaaagggt atttaatcaa acagaacttg caagcgatta ttccttctgt
    17401 caaatccgct tataatggac aggccgtatt tggtaatgaa atcatcgaga ctttcactca
    17461 aatgatgaag aataaaccga cgattgatag tcatgcttat gcttctttta gtgaacgtga
    17521 gcttgcaatc atcaaagaag tagctgccgg gaaaaacaat aaagaaattg cagatgcctt
    17581 gtacttgagt gacggcactg ttcgcaatta catcagccaa ttactagaaa agctagattt
    17641 acgggatcgc acgcaattgg ctatctattt ttatcagcat ttgcaataag tcttatctaa
    17701 cacaaaaaaa cctgaatgat gctccttcgc atcattcagg tttttttcac atcttctatt
    17761 caattgtccc gcaaaccatt tcctcacgat tgaaagaatc aaggattcgc agggctgcca
    17821 ggattcgttg gattgttcgg cgtgttaggc ggaaaaatag gcgccttgtc taacgttttt
    17881 tctagttttg attcttcacg atcgtctcgt tctacatcag gactttcatt caatttgaat
    17941 tctttttcca tctcatctaa ctttttaaag tcattgccag attcttttgc taatttcgct
    18001 aatttatctt cggtttcttt agccataaag taacgccccc cttttgattt cagcttagca
    18061 tatcacactg aaaaaacaaa agaaaacgct aaccaacgat catttttagc tatttctcat
    18121 ctttaaaatc aagcattttt tgccggtata aaatcgtagg gagaactgtt ttccatacca
    18181 atcatcggat ctactaactg gttatcgatc acttctgctg taagaacgaa atctttagaa
    18241 acagcaggtt ctacctcttc tttcttttct tctccaacaa atgaagaaaa cagatctggt
    18301 tccactgttt ccattacttg gtttttcgtt tcattcgtcc cactgtcatc ttctacaggt
    18361 agcttttctt ttacaacccg tggctctttt gtatagttcc catcttcaaa tggatcattt
    18421 ccgaccaaag aatcttcata agctgctagt ttggtccgga gagtgatatt cattttatca
    18481 ttatccatga tccttgattt caacgtagtc atccggcttg ctgattcatt cgctacacaa
    18541 gtgacatagg cttgctcttc ccctaacaaa atcaacagtt ccttactgcg agtcactgcc
    18601 gtgtagagca aattacgctg aagcatccgc tgatattgat ggaccatggg caaaataacc
    18661 atcttgaatt cactgccttg tgatttatgg attgagcaac aataagaaag agtgatttta
    18721 ttccattcgt ttcttttata agtgacctca tttgcatcaa actggataac taattcatcc
    18781 actttatctt cagaatcttt tgccaagatg atacccgtga tttctcccat atctccattg
    18841 aatacattca attcgggagt attgactaat tggaggactt tgtctcctat ccgataaacg
    18901 gtgtcgttcc aatgtacttc cttttttcca ggtttccctg gattgaatat ctcctgcatc
    18961 attttattta acgcatcgat ccctgcaggt ccccgataca ttggtgctaa tacttggata
    19021 tcttgtgcac ggaatccctt atttttcgct ttttccacaa ttttagagat caagggttca
    19081 atttgataag catcacttcg gaaataggaa cgatcttttt gattctttgt gaaatctttt
    19141 ggcagacgtc cttctttgat ctcatgggca agaggaataa tactagaacc atcaccttgc
    19201 cgataaatct gattgagttc cattttggga atttgttcga tttccaaaag atcatggagt
    19261 acttgaccag gaccgacaga gggaagctga tctttgtctc ctactaagat aacttgcata
    19321 ttcgtcggaa tcgctttgaa taatgtgtta gccagccatg tatcgaccat agacatctca
    19381 tcaacaatca aaagtccgcc ttctaattct ttcgtactga ctgaaggtgt tttttcccgt
    19441 ccattcagcc ccagaagacg atggatcgta ctggcaggca gacctgtcgt ttcgttcatt
    19501 cgtttagctg ctcggccagt tggtgctgca agtagaatag gaaaaatttc ttgggtatat
    19561 tttgaaggat ccaattccag tccgttcaac tctgcaaaaa gattgacgat tccgttgatc
    19621 acagtagttt tccccgtacc tggtcctcct gttaaaataa atagagggga acggattgct
    19681 tcagcgatag cttgttcttg cgaaggtcca tactgtatgc cgaatatttt ttcgatacgc
    19741 cgaatattct tctgcacttc tttttcagga taatggattt cttttttacg actgagaagg
    19801 cgctggatcg aattaccgat cccccattca gaaaagtaca aactgttttc gtaaagatta
    19861 gtctcttctt gttgtatctt tccttcttca acaagttgga taattacagt agcaacctga
    19921 tcaggctgga tttcaattgg gcgacttgtt tctaaaatac ggatcgtttg ctgaagcaat
    19981 gtctccgccg gtacgtatgt atctcctgtt tgaactgcat gctgaaaaat ctgatgcaag
    20041 atagctgctc gaattcttct cggtgaatct gctgcaatac cgatttgttc ggctagatta
    20101 tctgcacgtt tgaacccgat tccttctatg tcttcgacta gctggtacgg attttcttcg
    20161 atgatatcca aagactcgtt cttataggcc tggtagatac tgaaagctaa ctgactaccg
    20221 aacccgtaac gattcagtcc catgatcact tgatccatcc cgtggtttag ccgaatcgtc
    20281 tcagcaagca tttctctttt tggcttcgtc aaaccggaga tttgttttaa taccgaagga
    20341 tcagcaatga ttttttcgat agcatcttct cccagcaatt ctacaatttt ttctgctgtt
    20401 ttcttcccga ttcctgggaa tttttcgctg gaaagatacg ctacgatccc atttgcagtt
    20461 gttggctttt cttgctcata tctttcgagt ttaagctgcc ttccgtattt aggatgatcc
    20521 actaattctc cataaaaacg ataagtctca ttttcttgaa tatcgccgaa acttccggtg
    20581 actacaatct ctttttcacg gtaatcagct gtggtttcac tgatgtgtac caaaagcact
    20641 ttgtaaaaat tactaggatt ttgaaaaaaa atcgcggcaa ctgtaccaac gaaataaggc
    20701 atttcttctg gctgcatcgg aagccgcctc cttcttctat agtaaaggtt ctggtgctgt
    20761 ttcagttcct aaaaaatctg tttggttcca tactttcagt tcatatggca ataatctgca
    20821 aggctcttca gtctctaaaa tcgtcaaact actattgaac aatccaccca tttcacgcaa
    20881 ctcacttagc tcttttcctg tcatccattg aatggctgca gttaaagaag ctccatgtcc
    20941 tacgaataaa agtgggccat ctttatgtcg ggcaaccgca tctgctacaa cagtttcgat
    21001 acgtgtgatt gccgattcaa tcgtttctcc gtgaaaagga gaaggatcat acagatctaa
    21061 atgattacgc aaattcggca gattatccgg atatttctgg tacatttcat cgatcgactg
    21121 accttctaaa gtacccagcc ctagttctct tagcttatct gtataaaaaa tctctaccgg
    21181 acgagcaagc tctttgttga taccttctgc tgtatcacgt gctcgctttg ctgtactgga
    21241 ataaattgct ttaaaaggaa catattttac ctttttccca aatgctttga tttcttcgta
    21301 actttgtggc aaaagcggag aatcgccatt gctcccttga aaacgtcttt cctgattcca
    21361 ttgtgtcttc ccatgtcggg taaaatatag ttccatacgc agcaaactcc tgtctttctt
    21421 ttattttact ctataataaa ctgtctaatc cagcttgtca ttttcatagt gatgcgtcaa
    21481 ttctaaatta gggaatcctt gctggcgaag tgcttcatac actatcattg cagctgtatt
    21541 cgataaattc aatgagcgga catgctcatc attcataggg atgcgtaaac acttttcttc
    21601 gttttcacgc ataaatgttt ctggcaaacc ggttgtttct tttccaaata aaaagaagtg
    21661 ctcttctcca tcagcaaaat tttcgtcact atatacttta tgggcaaatt ttgagatcaa
    21721 atgtagttta cgattaccta aaaatgttaa aaaagcttct aaattactgt ggtaagtaat
    21781 atttacatca ttccaataat ccaaccctgc ccgttttaga tgtttgtcat cagttgaaaa
    21841 acctagtggc tcgattaaat gaagcggagt attcgtggct gcacacgtac gggcaatatt
    21901 tccagtgttt gcagggatta atggttcaaa taaaacgata tgattcatca ggatcattcc
    21961 tctcatattt atgttcgttt ctattttctg acaatttgat ttttgcataa aaaaaaacgt
    22021 atcaactcgg tgtcagtcac tgcgagtcgt tacgttagtg aagctcttct cactaacttt
    22081 tatcagaaca ggaacctgat aaaaaccaat gaaaaaacaa cttgttgcta atataacacc
    22141 ctcaactttt ttttgcaacc tctactcatt aaaaactgct agaaaaacgt tttctcttag
    22201 ttccttttaa taattctatg tcaattgtaa tcttcttcaa aggattctta tataagtctg
    22261 ctttgattcg ctcttctacc tgccattcta aaggtgacat ggccaaaaga tctttttgat
    22321 tttcctctgg tatctcaaat tcataggtta cacgctgacg ttcagttaat ttcattgctt
    22381 cagcaaactt ggctactaca cgttcattgg aataactctg tttttcaggt tgattcggat
    22441 aaaaagcctg acgtagttcc tttaaataat tttcttgtgg caccaccttc aacacttctc
    22501 catcttctga gagtacacgt tggaattctt ggtaatgaga aggcgaaaag atatttaaaa
    22561 ccgcgttgaa tgtttgatca gcaaacggca aattggtcaa atcagctaca caccaaaatg
    22621 cttcggcaga ttgttctgta gctgcgtaga ctccttcttt tgaaatatca aatccaacag
    22681 cattttgaat ctttttcaat tttgaaagtt cattcaagaa gctaccttct ccgcagccaa
    22741 catctaatag cgagacttct tcaggtaaat gctgcgcaat agtctcaata acgggctgat
    22801 acatgccaga ttggatcatt ctacgccttg gaacgaacat tccttgatcg tattctgttt
    22861 taaccgcatg ggataaaaaa taaagtgttc cttttttgga aaggtcaaaa cggtgattat
    22921 ttttgcatat caagccatta tcagactttt ttacttcttc ttggcaaacc ggacagcgga
    22981 acagctgatg attttctgcc aaaaactggc gtcctcggtc aatttttttt aacatagttc
    23041 cccctcattt ctgttttatc ttaccgttag atgctcactt tggcaactgc taaaaatatg
    23101 atacaatgcc tagaagaaag tgaaagataa aggagaagat tagatgatca aagaattttg
    23161 cgctgaaaac tacacatcta ttcctctagc aattgctaga ggagccgatc ggatcgaatt
    23221 gtgtgacaac ttagcggtcg gtggcacaac cccgagtact ggtgtgatcg aagaaacgtt
    23281 aagttatgct ggggaaaaag atatccccgt aatgacgatt attcgtccta gagggggcga
    23341 cttcgtctat aacgatatcg aattgaaaat catgcatact gatttgattg aagcaaagaa
    23401 attagggacg gatggcgtag tatttggttg tcttactcct tcaggctggc tagacgaaga
    23461 ggccttagaa ctattgatcg aaacagcaga agggttgcag atcaccttcc atatggcttt
    23521 tgacagtatt cctgaagatc ggcaattcga agcaatcgat tggctggtag aacatggtgt
    23581 tgaccgtatc ttgactcatg gcggtcctgc tgacaaaact attgtagaaa atttcccacg
    23641 gcttaaagaa ttgattgcct atacagatgg ccgcttaatc attttgcctg gtggtggtgt
    23701 cactgcagag aatgcagcac atgtagctaa agaattgaac gtaagcgaag tacacggaac
    23761 caaaatcgtg gatcttcagt tataatctta taaacaaaaa aacatttgca acaggcataa
    23821 tgcttattgc aaatgttttt gtttttttac ataaaatagc ccataaataa agaagcaata
    23881 ttgaaataaa tcagtacact cgtcaaatcg ctcaaagtcg tgataaaggg accgcttgct
    23941 actgctggat caaatcctag acgatccatt agcatcggga ttaaactacc tgcaagattc
    24001 gccactgtga ttgcaaatag catagccatc cctatgacaa accccaagat aaaattatgt
    24061 ttccaaaaac ctacgattag aaaaatcgtg atccccgtaa cagctcctgt gacaacgccg
    24121 gtcaagactt cagccaaaac aagtcgaaca aatccatgat ctttctcatc agaaatcgca
    24181 agtcgacgaa cagccacagc tagcgactgg gttccagcat taccggcagt tcctgtaatc
    24241 agcgaaatga agactgctaa aatactcgct tcacttacca agtcttcata gtgactgatt
    24301 aaagaagcgg tcgacatacc taaaaacaac agagtgatca gccaaggcaa acgtcgagac
    24361 gctgccttta ctggattttc attaatttct tccacattga ccccggcaag tcctgaataa
    24421 tcgctagcag cttcatcatc aataacgtcg atgatatcat cgactgtgac gattcctaac
    24481 aaatgatcat cataatcggt aacaggaaga gctaagaagt cataatctct aaatgtttgt
    24541 gccacatctt cttggtcgtc gcctacatga actgaaagca ctcgttcgct catcagatca
    24601 gaaatcattg cgtcgtcatc attcacgatt aggtcgcgca gagaaataac ccctactagc
    24661 tgaccttctt gattaacgac atagatgtaa tagattgttt cagctacatc tgcttcgttc
    24721 ttcagcacgt acatcgcaga gcgaacagtt tgattggcta cgatcgaaac aaattcagtt
    24781 gtcatgatcg cgccagccgt ttcatcctcg taatggagaa gttccttgat ttcactggca
    24841 tcgtctgccg acatcaaact taaatattta gcaatttgct ttttatccag cgtattaagc
    24901 aagtcaacag cattatctgt atacatctca gaaagcatat cagctgcata gctaggacgc
    24961 atttcatcta ggtattcttt catatgttcg ttgtcttctt caatcacatc gaacatatcc
    25021 gctaattctt taggcgacag ataggaatag atcagctgcc tgttctcttc tgtaagagat
    25081 tggtagaatt gcccctgctc atagatatgc atctctaaaa aactgtttct gaatgcctga
    25141 atattatttt cccttaaatc ttgagtcaac tgggcaaatc tttcctctaa ttcttgattt
    25201 tcatccaaac caatctcacc tcgccttatt cttcaaaccg tctcacaact gcctccatgt
    25261 ctgcggctaa aggctgcttg aactccagca actcttctgt aaatggatgg taaaaacgca
    25321 gatcataaca atgaagggct tgtcttttta ttcccagatc cattcgcccg ccatacatat
    25381 catcaccgag cagggcacag ccaattgcgg aaaaatgaac tcttatttga tgtgtccttc
    25441 ctgtatgcag ctggatatca actaacgcga tttctgttag tcgcttctct atccagtact
    25501 cagtctgtgc cgaacgtcct tcatcagaga ccattcgctt caatagcgaa gaataatctc
    25561 gggcgatcgg caaatcgata tgtccatgtg ccgataaatc tgaaagcctt ccactgacta
    25621 aggcctgata ttttttcaca aacttctttt cacgaagttg catatctaat tttgcgtgcg
    25681 caaatccatg ctttgcaaaa agcatcaagc cagatgtatc ccgatctagt cgcgtcacca
    25741 catggattac ttggttttcg taaccttgtt ttttataata agcctttaca cgattagcca
    25801 ttgtcccatt tggatggtat tgggcaggaa tagacgaaac gcctgctggt ttatttacta
    25861 ccagaacgtg ttcatcttca tacacgatat cgatcggtgt ttcatccaaa agtacggttt
    25921 catgttctcc ttcagcagga atcacaatgg ttaccttatc atccttagct agagaaaaca
    25981 agacattttc tacttgatca ttaactttga tttgaccgcc ttgaaatttt attttcgcta
    26041 acagaccctt tgagatccct ttttctttta aaaaatattt tacttgctga gaatgatctt
    26101 tctcataatc ccatgtaaac tgcatatcaa tcctcactaa taaaggcatc tttcacacga
    26161 tgccaaaaat gcatatgtcg ataagaagca aaatggatcc gttcttctgc tattcgataa
    26221 taaattgagc ggatatttgc ttttgcgaca ttcaattgat caaccgttac aagataatct
    26281 tctgtatttt ccaattttat ttctagccat tcatcatggg caatcacgat cggagaaccc
    26341 aaagtacgaa acactcgatt attcagtgaa gcaatctctg ccaactgaaa ggcattgata
    26401 ctaggatgga tcacagcacc gccgacactt ttattatatg ctgtcgaacc agtaggcgta
    26461 gaaatcgtca atccatctcc tctaaaactt tcaaacagct cgtttttgat gtatacatcg
    26521 gctaccatcg tacgattggc ccgtttaatc gttgattcat tcagtgctaa aaaatgctgg
    26581 tccggtgttt catccaaata actgatccga acatccagca agggataact aacactttgt
    26641 tcccggttcg ttcgtaagct gtctactagt tcttccagct cgtaatcccg ccaatccgtg
    26701 taaaacccta aatgacctgt atgcacgccc aagaaacgca catcattcag acaatgactg
    26761 tagtgatgga acgccgacaa taatgtgccg tctccgccga ctgagatgac caattctggc
    26821 tcatgatcat ctcgttgaat ccctgcttgt tctaaaagtg cgttcaaacg ttctgtcact
    26881 tctatagtct ttgcttcttt attatgaacg atcgctactt tcatcccctg cctcctctct
    26941 ttcgctttct ttcttcaaaa gcgttcgata gtagacatca tctgattttc ctcttccatg
    27001 ggagaataac cgctgtgctt cttggatttc ttcacggata ctggacatct cttcatccaa
    27061 ctgataggca gcttctgccg cacgctgaag tcgttcactc atttcttctg gaaaaacgcc
    27121 ttgatattta taattcagcg aatgctcaat cgttgcccag aaattcatcg caagagtccg
    27181 aatctggatt tccgccaaaa ttttcttctc accgctgatc agctgtacag gatactcgat
    27241 caccagatga taagaacggt agccacttgc ttttttattt gtgatgtaat ctcgttcttg
    27301 gagaactttc atgtcttttc ttttacggat gatctcaaca acttgatgga tatcttctac
    27361 aaactgacac atgatcctta acccggcaat atcagacatt tcttcttcta aacgtcccat
    27421 tggaatatgc cgtaattgtg attttgttac aatactatcg actggcttga ctctcccagt
    27481 gacaaattca atcgggacat gtcgattttg ttcacggaac tgtttgcgga tcccccgcag
    27541 tttcactttc aattctgata cagtttgttc atatggtgct aaaaatgctt cccaatctcg
    27601 ttccatagct gatacctcta cttcattaac attcattgtt tattctacca tatatgcaaa
    27661 gttttttcgt actcttgatt tatgcattga ccaaaaaaag aaaattaggc aaaatagaca
    27721 aaaaggagtc gatcaaatga cacaaatgct tgaaatcgaa tataaatcta tgctgacaaa
    27781 gcaagagtac gagatattca tcgctcacta tcaattaaca gataaagatt tccgtgtaca
    27841 gactaatatt tatttcgata ccgttgatga acagctgaag aaacaaaatt gtggcctacg
    27901 gatccgtttc gttggtcatc aagctgaata tacattaaaa acacctgctg aaaaagggcg
    27961 tctcgaaaca acggatacct ttataacaga agaagcagaa gcatttatct tcgaaaaacg
    28021 tctgcctcgt tcaggcgcag tttttcaaaa actttctgat ttgaatatcg atcctgcttc
    28081 attaatccaa accggaaagc ttacaacaaa acgagctgaa ttccctattg aagaaggact
    28141 tttagctatt gatgaaagct ggggagacaa tctacacgat tttgaactgg aactagaggt
    28201 aggggatgca tctgtgggaa aaattgcttt tataaatttt ttaaaacgtt tttctttacc
    28261 ttatcgtcct gctaagaaca agatccaacg tatgcttgaa gctaaaaatt agaaaccttt
    28321 cattttcaca aggcacttga gttcattttt ttactttttt ctgttaagtt ataggatgtg
    28381 aaagaatcta gtcactagtt gtatagaatc tattttgggg gagattcata tgatcgaaat
    28441 ctatttattt gttaatcctt taggggaata ctgtttcgaa atggaacaac agttattaca
    28501 atttatcgaa gaagagtacg ggacaccatc aaaagaaaag atgcaatttc gctttcttcc
    28561 tttggtcaat ttgcagacaa ttggggatgt catgcaacaa aaaggaattt ctcagaacaa
    28621 tcttgaggaa cgtaatcact tattctcaat gacttattct gcagcattgg actgcaaagc
    28681 ggcgcagttt caaggaaaga aaaaaggccg ccgttttttg atcaaattgc aagaagcagt
    28741 cggctgtaat gacataccat attctcaaga acttgctgaa tccatatttg aagaaatcgg
    28801 cggcgatttg aatatgttta aagaagatcg tcagtctgac ttcgttaaag aagtattctt
    28861 ttctgatcaa aaaattgctc gggaaatggg catcacaaaa cacccttctg cagtcgttta
    28921 caattatgcc tgcgaccgtg attttggtgt tttagtagaa gtaaaaggta caagtagcct
    28981 ttggagaatc acagagctgt gtaaaacaac agataactca tatcaagttt ttaatggtga
    29041 acatttacat acaaatgatt ctcagttcca ttcaagaact agccatttac acttgctttc
    29101 taa
//
LOCUS       DAFEKH010000034        28971 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.035, whole genome shotgun sequence.
ACCESSION   DAFEKH010000034
VERSION     DAFEKH010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28971)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28971)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28971
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.035"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(138..302)
                     /locus_tag="LP386_001719"
     CDS             complement(138..302)
                     /locus_tag="LP386_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918955.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            597..1925
                     /locus_tag="LP386_001720"
     CDS             597..1925
                     /locus_tag="LP386_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HBL1918956.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            2127..2960
                     /locus_tag="LP386_001721"
     CDS             2127..2960
                     /locus_tag="LP386_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HBL1918957.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            2976..3713
                     /locus_tag="LP386_001722"
     CDS             2976..3713
                     /locus_tag="LP386_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HBL1918958.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(3868..4836)
                     /locus_tag="LP386_001723"
     CDS             complement(3868..4836)
                     /locus_tag="LP386_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HBL1918959.1"
                     /translation="MKKILVLHTGGTITMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            5068..5901
                     /locus_tag="LP386_001724"
     CDS             5068..5901
                     /locus_tag="LP386_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HBL1918960.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            5935..6774
                     /locus_tag="LP386_001725"
     CDS             5935..6774
                     /locus_tag="LP386_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL1918961.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            6800..7360
                     /locus_tag="LP386_001726"
     CDS             6800..7360
                     /locus_tag="LP386_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBL1918962.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            7559..9280
                     /locus_tag="LP386_001727"
     CDS             7559..9280
                     /locus_tag="LP386_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HBL1918963.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            9445..10587
                     /locus_tag="LP386_001728"
     CDS             9445..10587
                     /locus_tag="LP386_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBL1918964.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            10603..11814
                     /gene="thiI"
                     /locus_tag="LP386_001729"
     CDS             10603..11814
                     /gene="thiI"
                     /locus_tag="LP386_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HBL1918965.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            12387..13034
                     /locus_tag="LP386_001730"
     CDS             12387..13034
                     /locus_tag="LP386_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBL1918966.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    13163..13379
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            13427..16072
                     /locus_tag="LP386_001731"
     CDS             13427..16072
                     /locus_tag="LP386_001731"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HBL1918967.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            16382..17695
                     /locus_tag="LP386_001732"
     CDS             16382..17695
                     /locus_tag="LP386_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HBL1918968.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            17685..18338
                     /locus_tag="LP386_001733"
     CDS             17685..18338
                     /locus_tag="LP386_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBL1918969.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            18393..19064
                     /gene="radC"
                     /locus_tag="LP386_001734"
     CDS             18393..19064
                     /gene="radC"
                     /locus_tag="LP386_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBL1918970.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGIYKLVHINYIRKFTVILPSGNTIMLSIIERHNAFFSS
                     SEDSL"
     gene            complement(18959..20311)
                     /locus_tag="LP386_001735"
     CDS             complement(18959..20311)
                     /locus_tag="LP386_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1918971.1"
                     /translation="MKRVALYMRVSTEQQAKHGDSLREQKETLYEYIEQHKDLKVVNE
                     YVDGGISGQKINRDEFQKLLQDVKENKIDLILFTKLDRWFRNLRHYLNTQEILEKHNV
                     SWNAVSQQYYDTTTAYGRTFIAQVMSFAELEAQIDSERIKAVMANKIAQGEVVSGKTP
                     LGYSIENKKLVINDDAPIVIDIFNYFLSSGSLRKTVYYLGSQYGIVRDYQSVKNMLTN
                     KKYIGELRNNKNYCPPIIDKKLFYAVQKALPKNLKTNAKRDYIFKGLLKCSDCQGSVA
                     GQTIKARYKKKDGTESIYERTCYRCVKRRNNKLRCTNKRAFYEKNLERYIFEATKQKF
                     EQIQINYSKKQPKIIKKKNSKKNIENKLDRLKKAYLNEVIDLEEYKKDREALMKELNE
                     IEVEPAKIDIKNVEFILSKEFDEIYKESSEEEKNALWRSIIDNIIVFPDGNITVNFLI
                     "
     gene            complement(20377..21666)
                     /locus_tag="LP386_001736"
     CDS             complement(20377..21666)
                     /locus_tag="LP386_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HBL1918972.1"
                     /translation="MGVLLFLVGIVLIIMGSSKLSEAKKLKDKTSALESKVKEYSQEL
                     NARETFISEKEKNISKLNKNLSTLENKIDILNAESQRLDDEINQKYDTSLVTIYKSVI
                     IPNIDETSSSEIKNKLSLLKIKEKDFILDGAINIPSYLNNREANNIKKKMLIPLESEI
                     TGLLNKLTISNVDSTREKIIRTFDKINKLFKNDEAEFKKELLELKLQELELNYSYIVK
                     VNDEKEQQKAIKEQMIEEEKVRREIEREKKRIDKEERQFNSEITKLMAYMQKASADVE
                     KELYADKIKELEEKLRELETVKEDVLQRELNTRAGYVYVISNIGSFGEDVYKIGMTRR
                     LEPMDRIKELSSASVPFEFDVHAMIFSEDAPTLENQLHSHFRKNEVNKVNQRKEFFKV
                     SLDEIEKVVLENYNGTVSFTKLAQAEQYRRSLELTDV"
     gene            complement(21753..22457)
                     /locus_tag="LP386_001737"
     CDS             complement(21753..22457)
                     /locus_tag="LP386_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family transcriptional regulator"
                     /protein_id="HBL1918973.1"
                     /translation="MFAENLKFLREKYNIDQQELAEKLGRKSSSSISEWEKGKYTPKL
                     KTLNEIAKIFNVDIDDLMNIDLSISNQIYNILPIYNQLNDENKVATYEFASNRLEEQK
                     QENVLDFPKKEKIPTVHNSASAANPTELTYGDTVVEEEEFERVPSAADFAVPIIGDSM
                     EPVIRNGQFVFVKEQPDVEDGEIAIVELGGDGVTCKEIYKDYENQTIILRSINDLYED
                     RIVSPEQIRIIGKVVF"
     gene            22657..22923
                     /locus_tag="LP386_001738"
     CDS             22657..22923
                     /locus_tag="LP386_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1918974.1"
                     /translation="MDTAKKEKYTLRQLRALKGYSKEELSRKSKVTSRTIFIYENDVD
                     KMRNGKYATLEKIAKALGVRVSDIFLDPDSEKPKSITGETKQVS"
     gene            22936..23094
                     /locus_tag="LP386_001739"
     CDS             22936..23094
                     /locus_tag="LP386_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918975.1"
                     /translation="MEEKNIKVPTLEEYTKIVVETDEQNPKTIAVITANDIESCEGFR
                     VRMTPRYD"
     gene            complement(23091..23321)
                     /locus_tag="LP386_001740"
     CDS             complement(23091..23321)
                     /locus_tag="LP386_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBL1918976.1"
                     /translation="MGKNQWVSPRNGKWAVRGEGNSEDTKLFDNKSDAVEYGKKISKK
                     QQSEFIVQKKNGQIQSKDSFGNDPIPPRDKEH"
     gene            23393..23548
                     /locus_tag="LP386_001741"
     CDS             23393..23548
                     /locus_tag="LP386_001741"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918977.1"
                     /translation="MSNKPKITLNGTPNLQRLADEMARIRSRHWGVTVVATIIEQKEK
                     PTQPASK"
     gene            23705..23860
                     /locus_tag="LP386_001742"
     CDS             23705..23860
                     /locus_tag="LP386_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918978.1"
                     /translation="MKEESKIGILNENNYTRLIIETEEGEKVAEVTLTDATPADGYRI
                     RLTPKYD"
     gene            complement(23857..24081)
                     /locus_tag="LP386_001743"
     CDS             complement(23857..24081)
                     /locus_tag="LP386_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBL1918979.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSPGNDPHPPKG"
     gene            24348..24683
                     /locus_tag="LP386_001744"
     CDS             24348..24683
                     /locus_tag="LP386_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918980.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            24916..25857
                     /locus_tag="LP386_001745"
     CDS             24916..25857
                     /locus_tag="LP386_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="HBL1918981.1"
                     /translation="MSKSTLEMSHQEWLEDRKRGIGGSDVATVLGLNKYKSPYQLWLE
                     KTGQIELKDLESEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPVIDGSGATADFLKEKYADVEENQTA
                     LPSRFDELIEQKRELKRTKKEIESAIRQVDNEIISELGKREASIGITQKNIISWKFVR
                     TRRMNSKKLAEKYPDVANDEEIYNVTESRRLTEKGIK"
     gene            25859..26749
                     /locus_tag="LP386_001746"
     CDS             25859..26749
                     /locus_tag="LP386_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HBL1918982.1"
                     /translation="MATNESLKNQLAEKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            26792..27592
                     /locus_tag="LP386_001747"
     CDS             26792..27592
                     /locus_tag="LP386_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HBL1918983.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWSLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADNIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            27607..28458
                     /locus_tag="LP386_001748"
     CDS             27607..28458
                     /locus_tag="LP386_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL1918984.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGSIA"
     gene            28455..28814
                     /locus_tag="LP386_001749"
     CDS             28455..28814
                     /locus_tag="LP386_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HBL1918985.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELEGKKYRKIEYIPDFTFYKSGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            28829..>28971
                     /locus_tag="LP386_001750"
     CDS             28829..>28971
                     /locus_tag="LP386_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918986.1"
                     /translation="MTTEEVIQMRIRSLRREIDDLERTKAVMVNETARKAIDLHIENL
                     RRE"
BASE COUNT         9747 a         4860 c         5852 g         8512 t
ORIGIN      
        1 taaataaagc ttatgcaaag aaaaagaaat ccaatcactt gggtttcttt ttcttttatt
       61 attatgatga atcaagcttt ctgtttttgt cacgtatgtt gtaatcttta cgaaagagta
      121 gagttggcta ctcataatca accatacttc ccatcatcgc taaatacgaa ataaatcagc
      181 attcctacac caatcaaagc acaagctgca ccaagaaaag ggatgacatt cccaaagtta
      241 tctgtattca taagtatgcc accacccaca aacaaaaagc cgccagcaat caggtttttc
      301 attttattca tctcctttct tacgttatag tatttccttc tttcaatgag tattttgaaa
      361 gctatcttat tgtatgatgt tcttctaggc ctcttcttta ttatacaggc cattttcgtt
      421 atctcataga aatattcctt tttatctgaa aactattgta taccgtatga catttttctt
      481 catgaagttg taagtatatt ctcattcaaa tgaaaatttc atcatagaag agattgtatt
      541 tctaaattct taagagtaaa atacgaagta taacttggat ttggaaggat gattggatga
      601 aagctattac gcctgatatg acaacaaaat ttaacaaaca gtttcaagca aatatcaaac
      661 agcaggcatt gcagcgggca gttgtgaaga acggaattac tgcttctgct gaaaatgttt
      721 cagcacatgt ggagaataca ccggtatttt ctatagattt ggctacgggg aaagtggcta
      781 atcaaatgca atcggggcgt tgctggatgt ttgctgcact gaacacattc cgtcataaga
      841 tgctgaatca attccattta aaagagtttg aattatcaca aaattacact tttttctggg
      901 ataaatatga aaaggcaaat tatttctatg aaaacatcat tgcaacagga aaagaggcaa
      961 tcgatagccg gaaagtagct ttcttactcg ctactcctca acaagatggc ggccaatggg
     1021 atatgatcgt ttcattattc caaaaatatg gcgttgtgcc taaatcggtg atgccggaaa
     1081 gtgcgaatag ttcaaattct cgagatttga ataactactt gaacaaatta ctgcgtaaag
     1141 atgcagtagt gttacggaaa atggttgctc aaggagaaac attagacgct attgaagaaa
     1201 agaaagaaga aatgctagaa agcatttata acttcttagc tatctcatta ggaacacctc
     1261 caaaagaatt cgattttgag taccgcgatg aagaaaagaa ctatcatctt gaccgaggac
     1321 tgacaccaca aattttttat gataaataca tcggtgtaaa attagatgat tatgttagcg
     1381 tgatcaatgc accaacaaaa gacaaaccat tcaatcgttc ttatacagta gagatgctag
     1441 gaaatgtcgt tggcgggaaa gaagtcaaat atctgaatgt tgatatggaa actttcaaaa
     1501 aattagcgat tgctcagctt gaagaaggag aatctgtttg gtttggttgt gatgtaggtc
     1561 aatcttctac tagaactagt ggcatcatgg ccttagatgc ttattcaatg gatgatctat
     1621 ttgatacgga ttttacaatg actaaagctg aacgtttaga ttttggagaa agtctgatga
     1681 cccatgcgat ggtattgacc ggtgttgact tagtagacgg gcaatcaaca aaatggaaag
     1741 tcgaaaatag ctggggcgaa aaagttggaa agaatggctt ctttgttatg agtgatgcct
     1801 ggatggacga atatacgtac caaatcgttg taagaaaaga tttattgacg aaagagcaat
     1861 taaatgcgtt caatgaagaa ccaattgttc tatctccgtg ggatccaatg ggtgctttag
     1921 catagacgag tatttcaatg aagagtatgt agtaaagata aaaagagctg gcttaagcca
     1981 gctcttttta tctttaaagt ccattccctg ttttttatgg tccctgtgct ataattctaa
     2041 ataaaggata aggattggaa ataatccttt tatcattaaa aatatgatga cgaagtagaa
     2101 taaaattggg agtagggggg aaagtcatgg atatccaaac tgttttatct gatctgaaat
     2161 taaatggtaa agtgattcca gttgttggtg gcgatgttaa tcagacctat cgtataaaaa
     2221 ccgaacatcg tgcttatttt ttaaaaatcc atccgaatgt aaaaaaagga ttttttgaag
     2281 cagaagtaga cggattaaaa gaactgtcag cattcgtacg tgtaccggat acgtatatgc
     2341 taggtgaaac aagtgaaggc gcttatttgt taatggaatg gatcgagccg ggaaaagggg
     2401 atcaacgaga tcttgctgca gctttagcta atctccatca gcaaacagcg ccacaatttg
     2461 gttttcgtaa agataactat ttgggtacac ttgttcagaa aaattctttt gaagaagatt
     2521 ggtggacttt tttctttaaa gatcggcttg aatcccagat ttctttggca gaagaaacga
     2581 atcgatggaa tgtacagcgt caagaaaagt atctgcgatt taaagaacgt gtattgaaat
     2641 cggttgaacc aaaaaagatc actccacgcc tcttgcacgg agacctgtgg agtggtaatg
     2701 tgttctttga ccagcaaggg catccagttt ttgtcgaccc agctgtttct tatgggaatc
     2761 gggaacaaga tattgcaatg agccagttat tcggtggttt ccgaccggaa tttttagatg
     2821 cttatcaaac tatatttcca ttagaaaagg gatggaaaga ccgactgccg atttaccagt
     2881 tatattatct tttggcacat ttgaatatgt ttggagaaag ttacggttcc caagtagatc
     2941 aattactaga aaatttttaa gaggagggcg tgtttttggc aaaaaaatat accaaaaagc
     3001 atgaagtttc atattatgag tgtgacatca accaaacgat gacatttcct tcgatgttag
     3061 gagtagttat caaaacgtct gaagatcaaa gcgaccagtt gggaagaggc agtgaattcg
     3121 tcaatagctt tggacttact tgggtcatca cgaattattc catggagatt aatcgtctcc
     3181 ctagagtcgg tgaagtaatc tcagtaacga ctcaagccat ggagtacaat aagtttttct
     3241 gttatcggaa cttctggatc catgatgaag atgggaaaga attagtcaaa atagaatctg
     3301 ttttcgtatt gatggatttt gtgaatcgaa aaatgagcag tgttaatgaa gagatcattg
     3361 ctccttttga gagtgagaag atcaagaaaa tcaagcgtca ggaaaaaatt gaaaagattg
     3421 attcgggctt catgttgcca tatcgtgttc gtttttatga tatcgatagt aatcagcatg
     3481 ttaataatgc gatgtatttt aattggatca ttgacgtatt aggatatgac tttttgacta
     3541 cgcatgttcc agaaaaagta attattcgat ttgataaaga agtagagtac gggaatgaga
     3601 tcgaaagcca ttttgaacaa atccctatcg aaaatggtgt caaaacaaaa catgaaatcc
     3661 gaatgcaaga acagctgtat tgtgaagcaa atattatatg gaaaaataaa taaaaaagag
     3721 gttgtgacag aagggggcaa cttcaagaaa taagaagaaa tttacgaaaa ttgtttctca
     3781 aatttttgta aattttcgac ttagttttcg aagaagctat ttttgtcaca gcctctcttt
     3841 ttaagtttag ctattagata atgatgttta gttttggata aacgaaatca attcttcacc
     3901 cgacaaacca tagtttacag caatcaatag ttttaaacgt gctttttgac tattaatact
     3961 gttacagaaa ataatcccca ttttttctag ttcttttccc ccgccttcat aatcataaac
     4021 aggctctgcg attccattga aacaacgaga aacaagtact acagggattt tttggacaag
     4081 aagcttttcc aaagcagcta aggcttgtgg agggagattc cccgcaccta aagcttcgat
     4141 taccaaaccg tctactttcg tatgggcgat ggcttccaat aagtcccctt gcatcccagc
     4201 atatgcttta acgatcggga tagtcccatc tacagcggaa atgtccagtc gctttgtttc
     4261 taaaagttcc tgcaagaata aaattcgatt cttagttact aagccgatgg gacccaatgt
     4321 aggtgttcgg aaagtagcaa catttgtggt atgggtcttt gtcacgtagc gtgcagaatg
     4381 gatctcatcg ttcatgacca ccaaaacccc cttatctagc gcttcttcac aacttgcgac
     4441 acgaatcgca ctttcaaaat tataaaggcc gtcacttcca agttcattac ttgaacgcat
     4501 tgccccagtc aaaacaattg gtaatttgtt gccaatcgtt gtatcaagaa aaaaagcagt
     4561 ttcttctaat gtatctgtac cgtgtgtgat caccactccg gatatacctg atgcataagc
     4621 ggacaagata cgttctttta ataccaacat gtgagaaggc atgatgtgtg gtgagggaag
     4681 attgaagata tcttcaacta ataattctac atgcttgggg attgtgattt ctgcatctaa
     4741 taatgggttt gccacatcag gactaacacc gcccgtgagc atgttttctt tcatggtgat
     4801 cgttccgccg gtgtgtagta caagtatttt tttcatttta cagacttcct tacgaataat
     4861 tttgcatagc cgttaaatct tattgtatac tatataaaag agttttgcta tcagtgaaga
     4921 ataacgaata gcctaactta tcataaaaaa gctgacctta ttaaaatgga aaagactcaa
     4981 ccttgacctc ctaatacaat ggagtatctg gttgagtttc ttttacaaga aagcagccaa
     5041 ggaaatcaat cacgaaggtg gccggaaatg atcagaatcg gattaacatc gtttaaagaa
     5101 catgacaaat taactggtaa aaagaataac actctttatg aatatgcagg gtttctaccc
     5161 ttagtggaat tagatactgc ctattatgga attccccgaa agtcctcagt tgagaattgg
     5221 ataagtgaag tacctgaatc atttcgcttt gtagtcaaag tctatcaagg aatcagcggt
     5281 caaggagact ggaagcctta ttatcagacc gaagaagaga tgattgcgca ttttttagat
     5341 gttatgtcgc caatggtaga tgctggaaag atgttttgct ttttagtcca attcccctca
     5401 tcattcaaat gtacgaaaga aaatgtccag tacttgcgca aacttagaaa gtggtttgag
     5461 ggttatcctg tttctataga attgcgggat tattcttggt acagcgatga atttcttgaa
     5521 cgtacaagaa actttatgtc tagagccgct ttttctttag ccatcatcga tgagccacag
     5581 ttgctgaata caacgattcc ttttgatcca tttgtcacca atccgaactt tgctcttttt
     5641 cgattccatg gtaggaatgc gcaaggatgg caagcaaatg ataaagagtg gcgtaaaaaa
     5701 agaacgttat atcgttattc agaaaaagaa ctgcaagaac tagcacatga agtcaaagta
     5761 gttgattcta agacaaaaga ggtaggtgtg atttttaata ataattctgg tggtgatgcg
     5821 gctgaaaatg cattagcact gcaaaaaata ttaaatatca agccagatgg actcaatcca
     5881 acccaaatgg atctgtttta agggcttatt ttattcaaga aaggggcgaa gtctatgatc
     5941 aaagctattt tttttgatat tgacggaaca ttggtcacca atcgttcaaa agcgttggaa
     6001 tcaacaaaac aagcaattga atatgctcgg aaaaacggca ttttatgcgg tgtagcaacg
     6061 gggcgcagcc cagtaaagat caaagaaatc attgatgaat tggaattaga tatgtatgtc
     6121 gtgtataatg gtcaactggt ttttactgca gatcgcacga ttatcgacca cccttttgaa
     6181 caaaaagtat tggaacatat tgttgaattt gcagatgaga accatcgaca aatcgttttt
     6241 ggtgcgagaa atcggttaga tggatcaacg acgatgctat taggacaatc gatttttatc
     6301 aagcgactag tcagcttttt accgcgtaaa ttcccggtac gtctgatgaa aaaaatcctc
     6361 caggttttta gccctcaccg acaaaaggat cgttatgaaa cgttagagat attaaaagaa
     6421 ccaatttatc aatgtatatt gctcagtccg gagtcagaac agaaaaagtt agaacatcgc
     6481 tttcccgagt gtacgtttca gcgttcaaat acgtatactg tagatatcat cccaaaaggt
     6541 ggttcaaaat tactaggcat ccaagctttc gcaaatgctg tcgaaattga aatggaagaa
     6601 attatggcat tcggcgatca ttacaatgat atcgagatgc tgaaaggtgt aggaattgga
     6661 gtggccatgg ggaatgctca gatcgaagta aaacatgctg cagactttgt gactcaatca
     6721 aatgaagaag atgggatata cgaaggactg aaacacttcg gtctgattta ttagtcaatg
     6781 aaagaaggaa aaaatcagta tggaagcaga gacacctttt caaaaagtag aaacattcca
     6841 caaaactttt gatccaagaa gaccagagat acccacggct tttacagaaa atgaagctca
     6901 tacacgtgct gcgttcaaaa tagaagaact tgttgaattt gttgcagcta cttcacctaa
     6961 taaagaacaa ctgcatgaag ctgttatgct gctgcacgaa gcattagata aagcagaaga
     7021 aaaaatactt ggtaaaacac agtggggaag tgatccgctg gttgaacaag tagatgcact
     7081 gacagatatc ctttacttta cttatggttc tttttcatta ctaggaatag tgcctgatcg
     7141 aatattcgaa atcgtccatc aggcaaatat ggggaaatta tttccagatg gaaaacctca
     7201 ttatgaccct gtaacaaata aagtgttgaa acctgaaaac tggcagatgg aatatgctcc
     7261 agaacctaaa atcgcggcag aaatccaacg tcagattcaa gaagcgattg ctaagaagaa
     7321 atccgctgat ataggcatgt gcacaaatga aaaagagtga tcagagtttc actatttttg
     7381 ttatctttat acgatggaaa aacaaaagat tttcgtttaa gttagtgaat gcatgaaaat
     7441 agtatgctat aatctagaat agatgtcttt tgcacgagag acgtattatt tggatttatg
     7501 ccaagcagaa cgccatctgt tgcataaaag atgcatactg aaaacggagg aaccataaat
     7561 gggaaataat gttatcatcg gaatcgtcat tgcaatcatt atagtcgcca ttgtcgtctt
     7621 tttggttagt tacttgatga agaaaaaaaa ccaagatcga ttggatgcct tagaaaaacg
     7681 caaggaagaa ttatttgact tgccagtgat tgaagaagtc gatgatgtta aaaaaatgca
     7741 tctggttggg caaagccaaa atacctttcg tgaatggagt caaaaatgga atgacatatc
     7801 tacttcctcg ttcgctgaac tagaaagtca aattttcgaa gtggaaaacc tcaatgaaag
     7861 ttttcggttc ttaaaaggaa aaaaagcagt tgttgaagca gaagctacaa tggaccaaat
     7921 ggagaaacaa gtgacggaaa tccgtgaagg tctaaaggaa ttgcgggaaa cggaagaacg
     7981 caactcacta gctgttcagc aggcacttga cgtctatgaa gaactgaaag aaaaagtcag
     8041 agaagacgag catgaatacg gaccagctct ttttgaattg caaaaacaga tcaaagtgat
     8101 cgaaaaagaa tttacgcagt ttgtgacttt aaacacttct ggagaccctg ttgaagcccg
     8161 cgaggttttg gataaagcag aaaaacatac gtatgaagtg gaagctctga tgaaaaaaat
     8221 tccaccgctg tatgaggagc tccataccac tttccctgaa caacttgaag aaatcagtga
     8281 tacttacgag aaattgatgg aagaacaata tgtattccca gaagaagatc ttgctgaaga
     8341 tatcgcaaaa gtaagtcgaa gaattgaaaa ttcattagcc aatcttgaaa aaacagaagt
     8401 tgaaacggtc gaatttgaaa accgtgaaac agctgatttg attgattcgt tatatgatat
     8461 cttagaacgg gaaatggaag ctcagagata tgtaaaaact aaccaatcaa cgattgcaga
     8521 gtatatcaaa catacaacaa agaataaccg tcaattattg attgagctgg atcacacatc
     8581 tcaaagctat acattgaacc acaatgaaat tggccgtgta cgaggtttcc aaaccgaagt
     8641 ggaagaaatg gaacgtcaaa atgaacagat gattccacag atccgtcaac acgaaattcc
     8701 ttattcagaa gtgcgcacgt tctataaaac agtcttcaaa gtcttagaag atatcgaaaa
     8761 gcaacaagta gagatcgacg actcattaca tgaattgaga aaaggcgaaa aagaagcgca
     8821 agaaaagatc gatacattcg aattcaaatt gcgcagtttg aaacgttttg tagaaaaaca
     8881 acgtttgcct ggcttgccga atgattacct agaattcttt tttgttgcta ctgaccgtat
     8941 tgaagaacta agtgttgtct tgaataaaat tcgagtaaac atggaagagg tcaatcgttt
     9001 agttgctcta tgtgaagaag atctagaatt attagataag aagacacatg atttagtaga
     9061 tgcagcagca ttaacggagc aaatgctcca atatgcaaat cgttatcgtc atacacacga
     9121 agaagtgaga gaagcaattg ataaaagcta ctatttattc aataaagaat atcactatca
     9181 agaagcatta gacgaaatcg gtacagcatt agagcgagta gaacctggtg ctttcaaacg
     9241 catcgaagat ttttatttta atcatccaga cttagtataa agcaaaaaag ttagtaaacc
     9301 agcaagagca agacggatta ttgtcttgtt cttgtctttt tttgtatatt tgaaaattga
     9361 aacaagtgaa aatttcacct gctcttgaaa gcaccttgga caaccgttat aatagaaaag
     9421 aatttcaaaa aagaggggtt tcttatgata tattttgata acagtgcaac aaccccaatc
     9481 tttccgcaaa gcttagatgc atatgtaaaa accagtcagc ggattattgg gaatccatca
     9541 agcttgcatg atttaggcaa tcaagctaac cggttgttgc agcaagcaag aaagcagatc
     9601 gctgatttga tccatgtaga accagaagaa atctatttta cttcaggcgg aacagaagga
     9661 gataactggg tattaaaagg aacgatgatc gaaaaaagag aatatgggaa tcatatgatc
     9721 atttcaggag tcgaacatcc ggccgtcagc gagacagcag aacaattaaa agaattagga
     9781 atcgaagtaa gtatcgcccc agtggataaa cgcggatttg tacgtgtcga cgaattgaaa
     9841 gaattaataa gaaaagagac agtattagtc tctgttatgg ctgtgaataa tgaagtagga
     9901 tcgattcagc ccatccagga aatcagtgat cttttggatg attttcctaa aattcatttc
     9961 catgtagatg ctgttcaggc gattggaaaa gtaccattct cgcaatggtt gacagaaaga
    10021 gttgattttg caacattttc agctcataaa ttccatggcc cacggggaac tggtttcatt
    10081 tattggaaaa agggtcgtcg tttagcacca ttactgacag gtggagggca agaaagaaat
    10141 cagcgaagtg ggacagaaaa tgttccaggt attgtggcta tggttaaagc tttacgttta
    10201 tcattagaga taaaggaaca aaaacctgag cagacacaac gcttaaaagt agctctaatc
    10261 aatgcgttga agacgtatga gaaagtgacg attttttcag aaggaactga ctatgcaccg
    10321 catattttat gttttgctct aaaaggaatt cgcggcgaag ttctcgtcca tgccttagaa
    10381 gaaaaacaaa tatttgtttc tactactagt gcctgctcct cacgtaaaca tatggcaagc
    10441 agtacattgc acgcaatgca tgtaccaaat gatctggcta catctgctgt tcgaatcagc
    10501 ttagatgaaa acaattcgct tgcagaagtc gagcaattta tgattatttt caagcagctt
    10561 tataagaaat tttctgcaat caattaaaag aggagtgttc ttgtgaaata cagtgaaatt
    10621 atggtccgtt atggggaact ttcgacaaaa ggaaagaatc gaaaaagctt tatcatgcaa
    10681 ctagcacaaa atgtcagaca agctttgaaa gactttccag aaatcaaaat ccatgctgat
    10741 cgggaccgga tgcatctttt attgaatggc gcagacgggc agctagttat tccaaaacta
    10801 gcaaaaatat ttgggatcca aaatttctct ccaagtattc gtgtagaaaa agatgtcgaa
    10861 gttttgaaac aagctgttca agacatcatg aaagaaattt atactgggaa agaaacattt
    10921 aaaattatcg ctaaaagaag cgatcaccaa tttgaattga caagtaatga attgaatcaa
    10981 acattaggta atgctgtttt tgatattttc ccgcatatcc aagttcaaat gcgtcaacca
    11041 gatattccat tacgtgtaga gattcggcgt gatggcgctt atctatcgta tgaaacgatc
    11101 aagggagctg gaggattgcc cgtaggaaca agcggaaaag gaatgcttat gctttctggg
    11161 gggattgatt ctcctgtagc agggtacttt gccatgaagc ggggagtgga aattgaagct
    11221 gttcattttg ctagtccgcc gtatacaagt gaacaagcac tgcaaaaagc aaaagatcta
    11281 acagccaaac tagcacctta tgtgggaacg atccatttta tcgaagtgcc atttaccgag
    11341 attcaagaag aaatcaaaaa gtcagtgcca caaggatatt ggatgacaat tactcgtcga
    11401 atgatgttgc gtttgaccga tgaaattcgc cgtattcgtc atggtttagt cattttgaat
    11461 ggtgaatcat taggtcaagt ggcttcacaa actttgcaaa gtatggtggc tatcaatgaa
    11521 gtaacgaata cgccaatcat tcggcctgta gcgacaatgg ataaacttga aatcattgaa
    11581 gtagcagaac agatcgatac atttaatctt tctatccagc cttttgaaga ttgctgtacg
    11641 atttttgctc ctccacagcc aaaaacacgc cctcaactgg aaaaggtcca tcaatatgaa
    11701 gagcgtttag caatagatga aatgatccaa cgagcactag ctggcttgaa gatggaagag
    11761 atacaagcag aatcgtctaa tgaaaaaact gaagaatttt cagaattgct ataagaggtt
    11821 atgaaaatag tgttttgacc agagtattag agaaacaaaa cgaaaaaata gctccatgta
    11881 ttttaccgtt tttgaactaa tgtcgaagat tagctgattg aataccattt atcaagaagt
    11941 tatggaaaag ccggttcttt tttactaact gaaaaataaa attttattta gagatcaagc
    12001 tacagttgat aaatgatata aaaaagagaa tttcccatga aatagcgagg ttgtgacaga
    12061 agtgggcagc ttcaagaaat aagaaggaat ttacgaaaat tgcttttcaa atttttgtga
    12121 aatttcggct tatttttcga agaagttact tctggaacac cgtgtatcag aggttgcgaa
    12181 aaagctgccc tgcatcaagt aataagaaca gccaaacaaa aatagttcct catattttac
    12241 gtttggttga gcttattacc gcagatgcaa gcttttgaac accgttttat ttgtctcaca
    12301 cccttttcct tcctacttgt aaccttgctc ccgtgttaga aacatgttac actaaatatg
    12361 tgaaattatt aacaaggagc gtcgttatgc gagaaaaaac agatacactg ccaaaagcaa
    12421 ctgcgaaaag attaccttta tatttacgct acttgaagat gctggatgac tcaggtataa
    12481 gtagaatcaa atcaaatgag ttcagcgaaa tcacccaaat tccttctgca acgatccgca
    12541 gagacttctc gcaattaggc gagctaggca gaagcggata tggctatgat gtcccttttc
    12601 ttatcgatgt attcaataat atccttaata ctaaagaaga aaaacgaatc gcattagtag
    12661 gatatggaaa tcttggcaaa gcattgaaac acaacaattt tagaagaaat gaaaatctaa
    12721 atatcgtgtg cgtctttgat aatgatccag cactgatcaa tcgagtaatt gatggagaaa
    12781 tgatctatcc gattgatcgt ttcgcggaga tagccaaagc aaaaaatgtg acagtagcaa
    12841 tctctacggt accaagtaaa tattcacaat ctgctattga tgaaattgtc aaaggaaatg
    12901 taaccgctat acttaatttt gcgcctgaca gagtaactgt cccagcttat gtcaatgttc
    12961 aatacattga tttgacaacc gagttgcaga cgcttattta ctttgatgag aattactcag
    13021 aagttttttc ttaggaaaat ttgagtaggc ttattgatct tgcgagaact cgtcgtaatt
    13081 ctttcaaaaa ttttttagta ctaaatgaag tggttttttc acgaccactt gttgactaaa
    13141 aaaaaaaacc attgtagaat gaagcataac gctgaacaag aggagtaact ggcacattca
    13201 ttcttagaga gagaactatc tgctgaaagg ttctcaatga caaccagtga aggtagcttg
    13261 ggagtttctg tcttgaatgg agtagagata gacgagtcgt gatcgttaac tcacttgaga
    13321 ggcaataatg attgattatt gcaatttagg tggtaccgcg taaatcatac gtcctagaat
    13381 acgaaagtat tttaggacgt tttttagttt aaaggaggaa aacagcatga cggaagaaaa
    13441 taacctatca acaaaatata atccgcaaga agttgaagct ggacgttatc agcattggtt
    13501 agaacaagat ttgtttaaac cgagcggaga taaaaaagca aaaccttatt caatcgtaat
    13561 cccgccccca aatgttactg gaaaacttca tttagggcat gcttgggata cgaccttgca
    13621 agatatgctg attcgtcaaa agagaatgca aggatatgat actttatggc tgcctggtat
    13681 ggaccatgca ggaatcgcga cacaagcaaa agtagaagcg aagcttagag agcaagggat
    13741 ttctcgttat gatctaggtc gtgaaaagtt catcgatcaa gtgtgggaat ggaaagaaga
    13801 gtatgcgagc cacatccgcg aacagtgggc taaaatgggc ttatctttag attacagtag
    13861 ggaacgtttt acattagatg atggattatc tgaagcagta cgtaaagttt ttgttacctt
    13921 atacgaaaaa ggtttgattt atcgtggtga atatatcatc aactgggatc ctcaagcacg
    13981 aacagctcta tctgatatcg aagttattca taaagatatc gaaggcgcct tttatcatat
    14041 gagctatgaa ctagcagatg gatcaggcgt agtagaaatt gcgacaaccc gtccagaaac
    14101 gatgttggga gatacggcga ttgctgttca tccagaagac gagcgttatc aagcgctcat
    14161 cggcaaaaaa gtgattctac ctttagtcaa taaacaaatc ccaatcattg cagatgaata
    14221 tgtagatatg gaattcggga caggtgtagt aaaaatcact ccagcacatg atccaaacga
    14281 ctttgaggta ggtaatcgtc atgatcttcc acgcgtaaat gttatggatg atgatggtac
    14341 gatgaatgaa ctagcaggaa aatatgctgg aatggaacgt tttgctgctc gtaaagcaat
    14401 cgtgcaagat ctgaaagaaa tcggtcgatt gattaaaatc gatacgatga tccacagtgt
    14461 gggtcattcc gagcggacag gtgtcgttgt tgaacctcgg ctgtctactc aatggtttgt
    14521 aaaaatggcg ccgttagcga aaaaagccat tgataaccaa gaaacagatc aagcagtgga
    14581 attcttccct ccaagattca atcaaacgtt tttacgttgg atggaaaatg tccatgattg
    14641 ggtaatctca cgacaattat ggtggggaca tcaaattcct gcatggtatc acaaagaaac
    14701 aggtgaaatg tatgtaggga tggaagcacc agcggatagt gaaaactggg tacaagatcc
    14761 tgatgtttta gacacttggt ttagttcagc tttgtggcct ttctcaacaa tgggctggcc
    14821 agatacggaa agcgaagatt ataagcgata cttccctact agcactttag taaccggtta
    14881 tgacatcatt ttcttctggg taagcagaat gattttccaa agcttggaat ttactggcga
    14941 acgtccattt gagaatgtct tgattcatgg attgattcgt gacgaacaag ggcggaagat
    15001 gagtaaatca ttaggtaatg gaatcgatcc gatggaagta atcgaaaagt atggagcaga
    15061 tgctctccgc tggttcttat cgaatggttc tgcaccagga caagatgtcc gcttcagcta
    15121 tgaaaaaatg gatgcttctt ggaactttat caacaaaatc tggaatgctt cacgtttcgt
    15181 tatcatgaat atcgaaggaa tgaccgtaga agagatcgat ttatctggag aaaaatcagt
    15241 ggctgaccgg tggatcctta ctcgtttgaa tgaaacgatc gaacgagtaa ctgagctatt
    15301 tgatcgtttt gaatttggtg aagcaggtcg acaactgtat aactttatct gggatgattt
    15361 ttgtgactgg tacatcgaaa tgagtaaaga agtactttat ggagatgatg ctgtttcaaa
    15421 acaaaccacc cgtagcatct tagtccatac acttgatcag atcctacgtt tattgcatcc
    15481 aatcatgcca ttcgttacag aagaaatatg ggaacatatt cctcatcagg gaaattctct
    15541 agtagtggca gaatatcctg ttgtacgtcc agagtttgat gatgaaacag cttctaaagg
    15601 gatggaagta ttgaaagaat tgattcgagc cgttcgaaat attcgttcag aagtgaatac
    15661 accattgtct aaaccaatta cgttgctaat taaaacaaac gatgctaaaa tcgatcaatt
    15721 tttagttgaa aatacaagct atatcgaacg cttctgtaat cccgaagagt tgacgatatc
    15781 aagtgagatc actgcgccag atctagcgat gtcagctgtt ctgacaggtg cagaaatctt
    15841 cttgccgtta gcaggattga tcaatattga agaagaaatc aaacgattag aaaaagaact
    15901 ggaaaagtgg acaagcgaag taaaacgtgt ccaaggaaaa ctttctaatg aacgttttgt
    15961 ttctaacgcg ccggaagaag tagtagaggc agagcgtgca aaagaaaaag attatttaga
    16021 gaagcaaacg gctgtcaaag aacgaatcga aagtttgcgt actattcaat aagaatagaa
    16081 aaagagagtg tgaaatcagc tagctattac taaaagctag ctgattgaac atcgttacag
    16141 gaaagagttt gagcctcact cttagcttcg attcataagg agatgtgaca taaattttgt
    16201 cgcatctctt ttttagtcta ctcttattat gtaggagaag gagggaggtg gatcatgtat
    16261 caagagtcaa taaagtagtt gataaaatcg ttcctctctc tgtttctttt ctctttgtca
    16321 tacttttatt tttcttatgt gttctatttg ttataataaa agagaaatgg gggaattgtt
    16381 gatgacgatt gaagaagcaa tagaatggat ccatagtcga ttaccatttg gttcacgtcc
    16441 tggccttgac cgagtcgaag ctttattaga agtggtaggg catccagaga gaaaagtaaa
    16501 aacgatccat atcgctggaa caaacggaaa aggttctact gtagcttatt tgagaagcct
    16561 attagaagag gctgggctga cagtaggtac atttacttca ccttatatcg aaacgttcaa
    16621 tgaacggatc gcaatcaatg gcaaaagcat tccagacaat gatttgatcc agcttgtaaa
    16681 aaaatatcag ccactgatca aacaacttga tcaatttgaa gcagtagctg gtattactga
    16741 attcgagaca ttaacagcaa tggcatttga ttattttttg atgaagaaag tggacgtagc
    16801 gattatcgaa gttggcttag gcggcttatt ggattctacc aatgtagctg taccaatgct
    16861 gacgggaata acaacgattg gacttgatca taccgaaata cttggagata caattgaaga
    16921 aatcgctgca caaaaagctg gaatcatcaa acaaggcgtt ccagtagtaa caggaaatat
    16981 tgccccagaa gcttttactg tcatccaaca aacagctaaa gcaaaaaatg caccgcttta
    17041 tgtatacggg gaaaattata aaataaacta tctgcatcct gatgagatgt ggggagaagt
    17101 atttgaattt tttaatgaaa taggaaagat ccctcaatta accactccgc ttttagggca
    17161 acatcaagct gaaaatgcag gagtagccat cgaattgtat tttgtttact gtcaattgga
    17221 aaagctgcct ttccgagaaa aagatgtttt gaagggattg aagaaatctc gatggccagg
    17281 aagaatggag cgtttgagta acgagccatt agttgtttta gatggtgccc ataatacgca
    17341 tgcaatgaac cggcttgttg agaatttgaa aaaagaattc aaaggatatc aaatcaacat
    17401 tttgttttcc gccttacgaa ctaaaaatgt tagagaaatg ctagaacgat tgcagcaagt
    17461 accaaatgtc catatttatt tgacgacctt tgaacatcca aaagccatcg aattaagtga
    17521 agtatcagat ttagcaagtg agagagtatc aatcgtttca ttgtggcaat tcggattagc
    17581 agatatattg gaaaagatga caaatgaaga cgtattagtt gtgaccggtt cactttattt
    17641 catttcagaa gttcgccatt tattaataca attaggagga gatcatgaag tataatgcag
    17701 tgatttttga catggatggt ttgctgttcg acacagagtt agtgtattac gaagccacac
    17761 aagtagtagc agacaagatg ggttttcctt atgataaaga cctgtattta aaattcttag
    17821 gtgtttcaga tgaagaagta tgggcgaatt atcatatgat tttctcggaa tttggcaaaa
    17881 caagtgtaca aagattcata gatgattcat accaggaaac gcttgaacgt ttttcgcaag
    17941 gagcggtaca aatgaagccc ggtgtgttgg aactcctctc ttttttagaa gaacatcaga
    18001 ttcccaaagt tgtcgcttcc agtaaccaac gagcagtcat tgaactttta ttgaagaaga
    18061 acaatctgtt tgaacgattt gagacgattg tttctgcaga aaatgttcaa cgagcaaaac
    18121 cagacccaga aattttcttg ttagctaatc agaagctagg tacagcgaag aaagaaacat
    18181 tgattttaga agattcacaa aatggtattt tagcagcttc tgcggctgag atcccggtag
    18241 tcatggtacc agatctgctt ccaccatccc aagaattgat caaaaaaaca gctggggttg
    18301 tttcttcttt acatgaaatc cctgcattgt taaaataaaa atccatctct tttcgtatct
    18361 tattttagat aagatagaaa ggagatgttt ttttgggaaa acgattgatc aaagaagtac
    18421 ctactagctc tttaccaagg gaacgtatgg aaatttatgg cgcggaagct ttatcggatc
    18481 aggagctttt ggcaatctta ctgcgtaccg gtcaacaccc ttatagtgtg atgtcgattg
    18541 ctggaaatct gttaaaaacg tttggaggac tggcctcttt acgacaggct actttgcatg
    18601 agttagaaga gattcgaggg ataggacgcg tgaaagcaat cgaaatcaaa gccttgatcg
    18661 aattaggtcg acgaattcag acggatcatg aaagagcggc tccaccggtt cgtaccagct
    18721 acgaattggc ccagcaattg attctggaaa tgaaagatca caaacaagaa catttggttt
    18781 gtatttattt ggacacgaag aatcaagtga tcttaaaaaa aacagtgttc atcggttcgc
    18841 tgaatcagtc agtcgctcat cctagagaaa ttttccatta tgctgtacgt tattgtgcag
    18901 caaggatcgt tttagcgcat aatcatcctt ccggaatata taagttagta cacataaatt
    18961 atataaggaa atttactgtt atattgccat ctggaaatac tattatgtta tcgataattg
    19021 aacgccataa tgcatttttt tcttcttccg aagattcttt ataaatttca tcgaattctt
    19081 ttgatagaat aaattcgaca ttttttatat ctattttagc tggctctact tcaatttcat
    19141 ttaattcttt cattaaagct tctcgatctt ttttgtattc ctctaagtct ataacttcat
    19201 tcaagtaggc tttcttcaat ctatctaatt tattctcaat atttttctta ctatttttct
    19261 ttttaataat ctttggttgt ttttttgaat agtttatttg tatttgttca aatttttgtt
    19321 tagtagcttc aaaaatataa cgttctaaat ttttttcgta aaaagcgcgc ttatttgtgc
    19381 aacgtaattt attatttctt cgttttacac atctataaca agtcctttcg tatatagatt
    19441 ctgtaccgtc ttttttctta tatcttgctt taatagtttg accagctact gatccctgac
    19501 agtcagaaca ttttaataaa cctttaaaaa tgtaatcacg ttttgcattt gtttttaaat
    19561 ttttaggtaa ggctttttga acagcataaa aaagtttttt atcaataata ggaggacagt
    19621 aatttttatt atttcttaat tcaccaatgt attttttgtt cgtcaacata tttttaacac
    19681 tttgataatc tctaacgatt ccatactgag agcctaaata ataaacagtt tttcttaaac
    19741 taccactaga aagaaagtag ttgaatatat ctatcacgat aggagcatca tcatttatta
    19801 ctaatttctt attttctata gagtagccta acggagtttt cccgcttact acttcacctt
    19861 gtgcaatttt atttgccata acagctttga tgcgttctga atcaatttgg gcttccaatt
    19921 cagcaaaact cattacttgt gcaatgaaag ttctgccata cgctgtagtt gtatcataat
    19981 attgttgaga aacagcattc caagaaacat tgtgtttttc taaaatttct tgagtgttta
    20041 aataatgtcg tagatttcta aaccatctat ctaattttgt aaataaaatt agatctattt
    20101 tattttcttt tacatcttgt aatagttttt gaaattcatc acgatttatt ttttgaccag
    20161 aaataccacc gtctacatat tcattaacta ctttcaaatc cttgtgttgt tcgatatatt
    20221 catagagggt ttctttttgt tctctaagac tatctccatg tttggcttgt tgttcagttg
    20281 atactctcat atataatgct actcgtttca tgttatctcc tttcgaatgt atgttcttat
    20341 cgttgtaaaa gaaaagcccg aaggctaatc tttttactac acatctgtta attctaatga
    20401 tcttctgtat tgttcagctt gagctagttt agtaaaagat acagttccgt tataattttc
    20461 taaaacaact ttttcaattt catcaagaga tactttaaag aattcttttc gttgattaac
    20521 tttattgact tcgttttttc taaaatgcga atgtagttga ttttctaatg ttggtgcatc
    20581 ttctgaaaat atcattgcat gaacatcaaa ttcaaaaggt acagaagcgc tactaagttc
    20641 cttaattcta tccataggtt ctaaccgtct agtcattcct attttataga catcttcacc
    20701 gaaagatccg atattactga tgacataaac atagccagct ctagtattaa gttctctttg
    20761 caatacatct tctttgacag tttctagttc tcttaatttc tcttccagtt ctttaatttt
    20821 atcagcatag agttcttttt caacatcagc actagctttt tgcatgtatg ccattaactt
    20881 agttatctct gagttaaact gtcgttcttc tttatcaatg cgtttctttt cacgttctat
    20941 ttcacgtctt accttttctt cttcaatcat ttgttctttt attgcttttt gctgttcttt
    21001 ttcatcgtta actttaacta tgtatgaata gttgagttct aattcttgaa gttttaattc
    21061 aagtaattct tttttgaatt ctgcttcatc gtttttaaaa agcttgttta ttttatcaaa
    21121 agttcttata attttttctc tagttgaatc tacgttagaa atagtaagtt tattgagaag
    21181 tccagttatt tctgattcta atggtataag cattttcttt ttaatattat tagcttctct
    21241 attattcaaa taagaaggaa tattaattgc accgtctaaa ataaaatcct tttctttaat
    21301 ctttaataaa gaaagtttgt tttttatttc ggatgaagaa gtttcatcta tattcggaat
    21361 aattactgat ttatagatag tgaccagaga tgtgtcatat ttttgattaa tttcatcgtc
    21421 taaccgctgg ctttcagcat taagaatatc aattttgttt tctagcgttg acaagttttt
    21481 attcaattta cttatgtttt tctctttttc agatataaac gtttccctag catttaattc
    21541 ttgagaatat tcctttacct tactctctaa ggcagaagtt ttatctttta attttttagc
    21601 ttcagataat ttgctactac ccataattat taaaactatt ccaactaaaa acaatagtac
    21661 tcccattcaa aacgcctcgc ttcttttata aaataattgt caaaatcata taaaccctta
    21721 ccgaagttga cggctccggc atgggaattt ttttaaaata caacttttcc gataattcta
    21781 atctgttctg gcgatacaat tctatcttcg tataagtcgt ttatagaacg taaaatgatt
    21841 gtttgatttt cgtaatcttt atatatctct ttacatgtaa ctccgtcacc acctaattcc
    21901 acaatagcaa tttccccatc ttctacgtcc ggttgttctt taacgaatac gaattgtcca
    21961 ttcctgataa caggttccat tgaatcgcct ataataggta ctgcgaagtc agcagcactt
    22021 ggaactctct caaattcttc ctcttcgaca accgtatcac cgtaagtaag ttctgttgga
    22081 ttggcagccg aagccgaatt gtgaacagtt gggatttttt cttttttagg aaaatctagg
    22141 acattttctt gtttttgttc ttctaatcga ttacttgcaa attcataggt agcaacttta
    22201 ttttcgtcgt taagctgatt atatatagga aggatattat atatctgatt agatatagat
    22261 aaatcaatat tcatcaaatc atctatatca acattgaata tcttagctat ctcatttaag
    22321 gtttttaatt ttggtgtata ttttcctttt tcccattcgc ttattgagga tgaacttttt
    22381 cttcctagtt tttcggctag ttcttgttga tcaatattat acttttctct aagaaacttt
    22441 agattttcag cgaacatagt aacacctcct tgagttaatt gtaacaccgt ttcggaaaaa
    22501 atgtaacagg tttcttagaa aatattttag tgtttttaaa gaagtattta cgcaaaatag
    22561 aaatcgattt caggaaaacc gaaatatgca cttgacttcg gaaaaaccga agtatataat
    22621 ttagtcagaa agttaaagag aggaggcgaa taaaatatgg ataccgcgaa gaaagaaaaa
    22681 tatacattga gacaattaag agctttaaag ggttattcaa aagaagaact gtcaaggaaa
    22741 agcaaagtga catcaagaac aatatttatt tacgaaaacg atgtagataa aatgaggaac
    22801 ggaaagtacg ccactctaga aaaaattgct aaggcattgg gtgttagagt ttccgatatt
    22861 tttttagacc ctgattcgga aaaaccgaaa tcaataacag gtgaaacaaa acaagtcagc
    22921 taggaggtgt gaatagtgga agagaagaat ataaaagtac cgactcttga agaatataca
    22981 aaaattgttg tcgaaacaga cgagcagaac ccgaaaacaa tcgcagttat tacggcgaat
    23041 gatattgaat catgcgaagg ttttcgagtt cgaatgaccc ctagatatga ttaatgttct
    23101 ttatcacgtg gaggtatagg atcgtttcca aaactatctt ttgattgtat ttgtccattc
    23161 tttttttgga caataaactc tgattgctgt tttttagaaa tctttttacc atactcaaca
    23221 gcatctgatt tattatcaaa tagttttgta tcttcggaat taccttcacc acgtacagcc
    23281 catttgccat ttctaggaga tacccattga tttttaccca taacaattca cctcgctttc
    23341 aagttaattc tattaagagg tgaaaagaaa acaaactgat ggaggtgaga ttgtgagtaa
    23401 caagccaaaa atcactttga atggcacacc taatcttcaa agattagcag atgaaatggc
    23461 tagaatacgt tctagacatt ggggagttac tgtggtggca accataattg aacaaaaaga
    23521 aaagcccaca cagccggcaa gcaagtagtg ggcaccatag aacaataata ttatatcaca
    23581 cactcgccac ttccgaaaag aggagttgct gctctccttt caagtttgcc aaagtccacg
    23641 tttcttcatt ttggcaactc ctcttcttgg aggtggtgac ggcgagagac gaaggaggga
    23701 tgacatgaag gaagaatcaa aaatagggat tttgaatgag aacaattaca caagattaat
    23761 tattgaaaca gaagaagggg aaaaagtagc agaagttaca ttgaccgatg caactcctgc
    23821 tgacggttat cgtattcgat taactcctaa atatgattaa ccttttggtg ggtgtggatc
    23881 gtttccggga ctatcacggc tttgaatttt tccatctctg ccatgaataa atagctcaga
    23941 tccttgattt ttagaaatct ctctagcgat ttttactgct tctgattttg tattagtatg
    24001 tgcagtcgct ttagaatttc cagcaccttt gacattccaa ccaccattgg aattaggtac
    24061 aacatgttga ttttttccca tagttttcac ctccatttct atagaaatat tttatcaaat
    24121 agaaatggag aaattcaata aacgaaagga gggatcaaat gacattacaa gagcatcaac
    24181 acttgatgcg aaaactaaat caggaatacc acgaggaaat gaaacctaga ttgctagggg
    24241 aacaatggcg tgaacgccag aagaagtggt tagaaataaa aaagtgactc agccgtccaa
    24301 agcaatgagt cacaaaccaa aaattatacc taaggagatt ttatcacatg aataagaaaa
    24361 ttgaaaatct tatcgaagaa ttgaaacgtg aatgccaaaa gcaaggtgtt tctattattt
    24421 gtacagccca aaaagaaggg gaacttaaaa gtctcgttta tggtgagaca acagaaattt
    24481 tactttgtct tgctatgcaa gaagaacatt tagatgaaaa tctcccattg tcagcacata
    24541 ttatgcgtag aattgctgtg gatgcttacg aacaagcgaa aaatgaagaa gaaaatcaac
    24601 cttcaaatca tacttttgtt attaataaca aggaagattt agctgatgtg atgactcgta
    24661 ttctcaaggg ggaatttcaa tgatgaatga aaaaacaatt gatctactca ttattttatt
    24721 tttcacgtta gtgattgtag cgaaaagtta tgtaatcttt ggcttgttat tcgcaattac
    24781 catgcttgtg ctttgcgtgt tagcaagcag aaaagaggtt aaacatgaac gagttagcaa
    24841 atcttgacaa ctatttaact gatcctgatt atgctaaacc accatatgaa gcgccaattg
    24901 atgaggagga tgaagatgag taaatctacc ttagaaatga gccatcaaga atggctcgaa
    24961 gaccgcaaaa gaggtattgg tggctcagat gttgcaaccg tacttggatt aaacaaatac
    25021 aaatctcctt atcaattgtg gcttgagaaa acgggtcaaa ttgaattgaa agatttagaa
    25081 agcgaaccag cttattgggg taatgtttta gaagaagtgg ttgctaaaga gtttcaggaa
    25141 cgtacaggca aaaaagtacg cagaagaaac caagtatttg aacatccatt acatccattt
    25201 ttaagagcaa atattgatcg ggaagtagtg ggagaaaatg ccattctgga atgtaaaaca
    25261 gccaatcaat ttctcggaaa agagtgggaa ggtgaagagg taccgcttag ctatctctgt
    25321 caagttcagc attacatgaa cgttttaaac aaagactatt gttatatcgc tgttttgatc
    25381 ggtggacaaa aattcatttg gaagcggatt gaacgagatc aagagctgat cgatacaatc
    25441 actgaacaat tagtagagtt ttgggaaacg aacgttcttg gaggtatcga gcctgtaatt
    25501 gacggaagtg gagcgactgc tgacttctta aaagaaaaat atgcagatgt agaagaaaat
    25561 caaacagctc taccatcacg ttttgatgaa cttatcgagc aaaaaagaga actcaaacgg
    25621 acgaaaaaag aaattgaatc agctatccgt caagtagaca acgagattat cagcgagcta
    25681 ggtaaacgtg aagccagtat cggtatcact caaaaaaaca tcatcagttg gaaatttgtc
    25741 cgtacgagac gtatgaactc gaagaaacta gcagagaaat atccagatgt cgcaaatgat
    25801 gaagagattt ataacgttac tgaatcaaga aggctaaccg aaaaggggat caaataatat
    25861 ggcaacaaat gaatcgttaa aaaatcaatt ggcagaaaag ccacagaaac aagttgcacc
    25921 aggacagtta gggcttaaag ctctaatgaa tacaccaaca atgagaaaga aatttgaaga
    25981 agtacttcat gacaatgcta atgcttttat gtcgaatgtt atgactcttg tatctaatga
    26041 cagttatctt gcagatagtg aaccgatgtc tatcatgagt ggtgcgttaa ctgctgcaac
    26101 attaaatctt gggctagata agaatttagg ttatgcatat ttagttccat tcaatagtaa
    26161 aaacaagcaa acaggaaaat gggaaaagaa agctcaattc atgcttggct ataaaggata
    26221 tatccaatta gcccaacgat caggtaaata caaagcatta aatgtgatcg aagtttacga
    26281 aggagaacta aaaagctgga accgactgac agaagagttt gagtttgatc caaatggtag
    26341 aacgtctgat gaagtcattg gatatgttgg ctatttcgag ttactgaatg gattcaaaaa
    26401 aactgtctat tggaccaaac aagaaatcga agctcatcgg attgctaaca ataaagatcg
    26461 cgataagaca aagttaagtg gtgtgtgggc atctgattac aatgcaatgg cacgaaaaac
    26521 tgttttgaga aatcttcttt ctaaatgggg aatcttgtcc atcgaaatgc aagaagccac
    26581 cacatcggat gagagagtcc aaagggttca agaagacggc agcattattg ctgaaacaga
    26641 agttgaagaa gatattcctg aaagaaaaga agcagaggtt atatctgaag aaaatgaaga
    26701 tgtacaaact ggattatttg atgcatctaa tccgccgtta aacaaataat gagggagctt
    26761 tctcccttgc ttttctagag gagaaatacg aatgaacaca ggatatgtca aattacatcg
    26821 aaaagtgatg aattcattcg tttggaccaa tccttatatg tataaattat ggagcttgtg
    26881 tttgatgaaa gcgagtcatg agaatcgcaa gatacttttt aatggaaaag agatacaagt
    26941 gaacagcgga gaattcgtca cagggcgcga tgctatcaca tctgagatga acgaaggcgt
    27001 gaaacgtgaa catcaagtga acagcggttc tgtatggaga tggctaaaac aatttgaaaa
    27061 aaacggaatg ttgaacatca aatcaactac gaaatacagc gttatatcaa taaaaaactg
    27121 gtctttgtac caaagcagtg aacaacaaat gaacatcaaa cgcacaacaa gtgaacaaca
    27181 agtgcacaca aacaagaatg aaaagaatta taagaatgaa aagaataata aaacatcatc
    27241 gtcgcaacca cgcaaaaagc gtgtttacga caccgactca gtttactaca ttctcgcgga
    27301 ggagttattc aaacagattt gtcagaatca ggaaatcaaa aagccgaatc tgcaaagttg
    27361 ggcagataac attcggaaaa tgatcgagat cgacaagcgg accgaaaacc aggtacgggg
    27421 aatgattgaa tggagtcagc acaatgtgtt ttgggcatcg aatattttat ctgctaaaaa
    27481 attgcgagaa aaatacgaca caatggcagc gcaagcaaat cgtgattata aaacaaaaca
    27541 aactaaaacg cttgaatacg agaaatttag cacagatgag ttgcctattt gagaggaggc
    27601 gtaggcatgg aaactgttgg ggaaatcatg gaaaagctga tacagaaagt gcttgtccaa
    27661 cgtggcgaat gtcctgaatg cggacagcct ttgtatggat ggcgtacgaa gaaccctgat
    27721 ggctcagaac gttgtaagcc aacctgtatg caatgtgggt ataaagcatt gcgagttcag
    27781 gaagacttac aaacagaacg aatttacaac gagagcctga aagcaagagc aatcaatttt
    27841 ttcaaaggtg gttctgttgt gcctaatcaa gcgttgtttg attgcacatt gcagaattat
    27901 caaattgtcg atcaagaaac aagacaagcg gttgaagtaa ccaaacgctt tgttaattca
    27961 gtcttgttag gaaatccaag tcaccttgtt ttaactggaa aacaaggaac aggtaaaagt
    28021 cacctagcga tggcagcggc ttgggaagtc ttgaagcgat caaactacga taaaaaaatc
    28081 ttatttatcg ggttacagga aatgctggat caaatcaaat tttcgtacaa caatcctgaa
    28141 ctcagaaaaa cgattgaggg atcgttgatt gcagatatca aaacagcgga tttagtcatc
    28201 attgatgata tcggttcaga actaggaaaa gatgcatcag atagtcgagc gtttggcata
    28261 aacacgctaa attcgttctt ggatgcacga cagaacctag caacgattat cacaacgaac
    28321 ttgcttggtg aagaactgaa aaaagcttac ggtacgagaa caatatcaag aatgtttgtc
    28381 aactctgatg gatttacgat ggtattttct caaacagcag acaagcgcat aaaaccagtg
    28441 aaaggtagta tcgcatgaat aaataccgta ataaaaaaac tgttcatcga ggtatcaagt
    28501 ttgattctat cgcggaagca gagtattacg atctagcctt gtggcaagct gaagcgaatg
    28561 gttggaaagt gaagctccag gaaaggtttg agctgatgcc gaagtttgaa ctagagggca
    28621 agaagtatcg caagatcgag tatattcccg acttcacatt ttacaaaagc ggcaagctgg
    28681 tcaaagtcgt agatgttaag gggatgcaga caaaagactt taagatcaag gcaaagttgt
    28741 tctgtcatca atatcaagtg ccgttgatat tagccaaaaa atatcggaat acgttcaagg
    28801 aagagcgttt ttaacgaggt ggtccatcat gacaacagaa gaagtgattc aaatgcgaat
    28861 tcgaagcctt cggcgtgaga ttgacgatct ggaacgaaca aaggcagtga tggtcaatga
    28921 aacggctaga aaggcaatcg atttgcacat agagaattta agaagggaaa t
//
LOCUS       DAFEKH010000035        28829 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.036, whole genome shotgun sequence.
ACCESSION   DAFEKH010000035
VERSION     DAFEKH010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28829
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.036"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(44..682)
                     /gene="plsY"
                     /locus_tag="LP386_001751"
     CDS             complement(44..682)
                     /gene="plsY"
                     /locus_tag="LP386_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HBL1918987.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            809..1243
                     /locus_tag="LP386_001752"
     CDS             809..1243
                     /locus_tag="LP386_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HBL1918988.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            1409..3454
                     /gene="parE"
                     /locus_tag="LP386_001753"
     CDS             1409..3454
                     /gene="parE"
                     /locus_tag="LP386_001753"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HBL1918989.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            3466..5916
                     /gene="parC"
                     /locus_tag="LP386_001754"
     CDS             3466..5916
                     /gene="parC"
                     /locus_tag="LP386_001754"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HBL1918990.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDRSIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            6193..8424
                     /gene="pflB"
                     /locus_tag="LP386_001755"
     CDS             6193..8424
                     /gene="pflB"
                     /locus_tag="LP386_001755"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBL1918991.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            8668..9429
                     /gene="pflA"
                     /locus_tag="LP386_001756"
     CDS             8668..9429
                     /gene="pflA"
                     /locus_tag="LP386_001756"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HBL1918992.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            9514..10440
                     /locus_tag="LP386_001757"
     CDS             9514..10440
                     /locus_tag="LP386_001757"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HBL1918993.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            10622..11515
                     /locus_tag="LP386_001758"
     CDS             10622..11515
                     /locus_tag="LP386_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HBL1918994.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            11649..11774
                     /locus_tag="LP386_001759"
     CDS             11649..11774
                     /locus_tag="LP386_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1918995.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(11908..12540)
                     /locus_tag="LP386_001760"
     CDS             complement(11908..12540)
                     /locus_tag="LP386_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918996.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(12688..13230)
                     /locus_tag="LP386_001761"
     CDS             complement(12688..13230)
                     /locus_tag="LP386_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HBL1918997.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            13365..13754
                     /locus_tag="LP386_001762"
     CDS             13365..13754
                     /locus_tag="LP386_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1918998.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            13758..14522
                     /locus_tag="LP386_001763"
     CDS             13758..14522
                     /locus_tag="LP386_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBL1918999.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            14651..15598
                     /locus_tag="LP386_001764"
     CDS             14651..15598
                     /locus_tag="LP386_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1919000.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            15728..16468
                     /locus_tag="LP386_001765"
     CDS             15728..16468
                     /locus_tag="LP386_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919001.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(16759..17427)
                     /locus_tag="LP386_001766"
     CDS             complement(16759..17427)
                     /locus_tag="LP386_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL1919002.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            17561..17848
                     /locus_tag="LP386_001767"
     CDS             17561..17848
                     /locus_tag="LP386_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919003.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            18264..19802
                     /locus_tag="LP386_001768"
     CDS             18264..19802
                     /locus_tag="LP386_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HBL1919004.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            19799..20764
                     /locus_tag="LP386_001769"
     CDS             19799..20764
                     /locus_tag="LP386_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1919005.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            20751..22073
                     /locus_tag="LP386_001770"
     CDS             20751..22073
                     /locus_tag="LP386_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBL1919006.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      22136..22240
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            22314..23057
                     /locus_tag="LP386_001771"
     CDS             22314..23057
                     /locus_tag="LP386_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1919007.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            23072..24064
                     /locus_tag="LP386_001772"
     CDS             23072..24064
                     /locus_tag="LP386_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL1919008.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            24076..24813
                     /locus_tag="LP386_001773"
     CDS             24076..24813
                     /locus_tag="LP386_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1919009.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            24803..25525
                     /locus_tag="LP386_001774"
     CDS             24803..25525
                     /locus_tag="LP386_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBL1919010.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(25609..26232)
                     /locus_tag="LP386_001775"
     CDS             complement(25609..26232)
                     /locus_tag="LP386_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL1919011.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQP
                     VVQETVQTEKQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYI
                     GRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            26627..27318
                     /locus_tag="LP386_001776"
                     /pseudo
     CDS             26627..27318
                     /locus_tag="LP386_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
     gene            27526..27816
                     /locus_tag="LP386_001777"
     CDS             27526..27816
                     /locus_tag="LP386_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919012.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
BASE COUNT        10005 a         4825 c         5950 g         8049 t
ORIGIN      
        1 gatttgtcac actcccgttt tatctctttg gaatgaaaaa gtatcaggat tttttcttgc
       61 tgctattcaa accaaacggg attcgacttt cagtatggtt tctgatacgc ttgatattgt
      121 ctttatgccg ataaaagata aaggaagaaa ctaaaaaggc aatgatcgtc agtaaccaat
      181 tgggcttagc caaaatcaca ggagctacat aaggaaggac gatcgtagat aaagtgatca
      241 atactgcact gatcatactg ctcaaactca ccatacttgt acaaaataaa ctaacgataa
      301 agatgataca agaataaaca aaaaatacag gattaaatcc taaaagcatt cctgcacttg
      361 tcgcaacagc ttttcctcct ttgaacccag caaaaatcgg aaatgtatgg ccaagaatgg
      421 cgcatacccc aaaccaaaga gggttaatcc cagaaaggtg gaagatcatc ggcaaacaag
      481 tagccaatgt accttttaaa atatccataa gcaggacaac aatcccggct gttttgccta
      541 atacacgaaa tgtattggtc gttccagtat taccgctccc gtgttgtcgg atatcttttt
      601 tgaaaaacaa tttgccaatc cagacaccgg aaggaataga acctaaaaga tatgctaaaa
      661 taagtaataa gatcaatttc attttttacc ctctttcaag ttgaaaacta tcctttattt
      721 tagcatgaat aggtaacagg aacaattgaa aaaatgaaag atacaagtat aatagatgga
      781 ataaaaagaa aagcaagggg tggcagaaat gtctgtaaaa aatccaacac aagaaacgat
      841 tttcaactat ttggaagaag caaaaaatat tgccgtcgta ggcttgagca ataaaccaga
      901 acgaacaagt tacatggttg cacaggtatt gcaagacaat ggatataaaa tcataccagt
      961 aaatccatta ttggctggtg aagaaattct aggcgagaaa gtctatgcga atttgacaga
     1021 aatcgatgat ccaatcgata tcgtagatgt atttagacgg agtgaatttt tacctgaaat
     1081 agcaggtgat tttttgaaaa ctgatgctaa agtgttctgg gcacaattag ggattgaaaa
     1141 caaagaagca gctgagatgc taagaaaagc aggacgtaca gatatcgtaa tggatcgttg
     1201 tattaagatt gaacttggta agttgaaaga aaaccaaaaa taaaaatgac cacaaagaag
     1261 agatgatcga tagaggggaa tgtcgaaaaa gcggttagga gataattaaa attgatttct
     1321 cgtctaccct cttttttttc acgacctttt ctagtatgat aatcgtggtg cggttttgcc
     1381 gcaaagtatt attgaaggag cgtttgcctt ggcaaaaaaa gtaaacaacg aatacaatga
     1441 ctcgtccatc caagtattgg aaggattaga ggcagttaga aaaagaccag ggatgtacat
     1501 tggatccact gacagccgag gcttgcatca tttagtctat gaaatcgtcg ataatgcagt
     1561 tgacgaagca ttatcaggtt atggcagtga gattgatgtg accatccatg aagacaatag
     1621 tataactgtt gcagatagcg gacgtgggat gcctgtagga atgcatgctt ccggaatacc
     1681 aacagttgaa gtgattttta ctgtgctgca tgctggcgga aagtttggtc aaggagggta
     1741 caaaacttct ggtggactgc acggtgtagg agccagtgtg gtaaatgcct tatcgaaatg
     1801 gctaattgta acgatcgtta gagatggcgt agagtatcag cagaaattta aaaacggcgg
     1861 taaacctgac ggtactttga aaaagatagg aaaaacaaaa aaagcaaacg ggacgactgt
     1921 ccatttttta ccagatgata caatattcag tacaacgaaa ttttcatatg aaattttagc
     1981 cgaacggtta agagaatctg cctttcttct aaaaggcgtt aaaatctctc tttctgatct
     2041 tcgtggagaa gaaccagtca aggaaatttt tcattacgaa gaaggaatca aagaatttgt
     2101 tgattatctg aatgaagaaa aagatacatt gacaccagtt gtttattttt caggagaaaa
     2161 agaaggtatc gaagtagagg tcgcttatca atacaatgac ggttattcag aaaatgtttt
     2221 atcttttgtc aataacgttc ggacaaaaga tgggggaacc catgaagctg gtatgaaagc
     2281 ggcgatgacg aaatcttata atgaatatgc gagaaaagtt ggtttgctga aagaacggga
     2341 caagaatctg gaaggtagtg atttcagaga agggttagct gctgtacttt ctatccgtgt
     2401 acctgaaaat cttctgcaat ttgaagggca aacaaaagaa aaacttggta cgccagttgc
     2461 tcgtaccgta gtagataacg tcatcagtga acaaatgggc ttttatttgc aggaaaatag
     2521 cgaaatgagc cagatgttgg tccgtaaagc aatcaaagcc agagaagcga gagaagcagc
     2581 acgtaaagcc agagaagaaa gccgaaatgg gaagaagcgt aaaaaaggcg aatctcttct
     2641 ttcaggaaaa ttgacacccg cacaatcccg aaaccctaag aaaaatgaat tgtatttagt
     2701 cgaaggggat tctgctggcg gatctgctaa acaaggaaga gacagaaagt tccaagcaat
     2761 tctaccttta cgaggaaaag tcatcaatac cgaaaaagct aaaatgcaag atatcttgaa
     2821 aaatgaagaa atcaatacga tgatctatac gattggtgca ggagtcggtc ctgagttttc
     2881 tatcgaagac tgtaattacg acaaagtaat catcatgacc gatgcggata cagacggcgc
     2941 ccatattcaa gtattactgc ttactttctt ttatcgttat atgaaaccgc tgattgaagc
     3001 tgggaaagta tatatcgcgt taccgccttt atataaagta tccaaaggac aaggaaagaa
     3061 gcaagtcatt gaatatgcgt ggacagatga cgaattggca gcaatgatta aaaaagtcgg
     3121 caaaggatat atgctgcagc gatataaagg acttggagag atgaatgcgg aacaattgtg
     3181 ggaaacaacg atggatccga cttcccgtac gttgatccgc gtccgtatcg atgatgctgc
     3241 gcaagctgaa cgtcgagtaa ccacactgat gggtgacaaa gtagaacctc gaagaaaatg
     3301 gatcgaaaat cacgtgcaat ttacgctcga agaagatggc agtatcttag ataaaaaaga
     3361 ggatactgaa atctctcctt cagtttctaa tgatttatta gatgaagaac gagcagataa
     3421 aaatgaaaac aatcagttat ttgaagtaga ataggaggtc acctgatgga aaatcgacaa
     3481 gaagtacaag aattaacttt agaagaagtg atgggtgacc gcttcggacg ttattccaaa
     3541 tatattatcc aagaacgtgc actgcctgat atccgtgatg gattgaagcc agtgcaacgc
     3601 cggatattat ttgccatgaa caaagatggc aatacgtatg acaaaggatt ccgtaaatca
     3661 gcaaaatctg tcggaaatat catggggaat tatcatcctc atggtgaccg cagtatttat
     3721 gaagcgatgg tccgcatgag ccaagactgg aagttgcggg aagtactgat cgaaatgcac
     3781 gggaataacg ggagtatgga cggtgatcca cctgctgcga tgcgttatac tgaagccaga
     3841 ttatccaagt taagtggaga gatgctagca gatatcgaga aagaaacagt cgatctcgtg
     3901 tggaattttg atgatacaga aaaagaacca acagtccttc cagctcgata cccaaacctt
     3961 ctcgtcaatg gatcgacagg tatatctgct ggatatgcaa cagaaatccc gactcataac
     4021 ttagctgaag tgatcgatgg cacaatctat atgatcgatc atccacaagc gagccttgaa
     4081 aaattgatgg aatatattcc tggacctgac tttccaacag gagggatctt gcaaggaaaa
     4141 gatgaaatca aaaaagctta tgaaacagga cgaggaaaag ttattcttcg ttcgaaaaca
     4201 aagatagagg caatgaaggg taataaacag caaatcgtga tcacagaaat cccatatgaa
     4261 gtaaataaag cgaccttggt gaaaaaaatg gatgagatcc gtttgaataa gaaaatcgat
     4321 ggaatagctg aagtacgaga tgaaagtgat agaacaggtc tgcaaattgt cgtcgaattg
     4381 aaaaaagacg ccaatgctca aggaattttg aattatttgt tcaaaaacac tgagctacag
     4441 atcaattaca atttcaatat ggtcgctatc gaccatatga ctccgcatca agttggactg
     4501 aaagacattt taagaagtta tatcgagcat cgaaagcaag tcataacaaa acgtagtcaa
     4561 ttcgatttag ccaaagctca aaaaagacag catatcgtag aaggattgat gaaagcttta
     4621 tcgattctgg atgaagtaat cgcaacgatt cgtgaaagta aagacaaaaa agacgccaaa
     4681 aagaatttag tcgacgtctt tcaatttaca gaagaacaag cagaagcaat tgtcacattg
     4741 caattatacc gtttgacgaa cacggatatc acagagcttc aaaaggaatc cgaaagcttg
     4801 attgcgcaaa tcacagagtt gaataaaatc ctttcaaatg acaaagagct tttctctgtt
     4861 atgaaaaaag aattgcgaga agtgaaaaaa aattattctt ccgctcgtct aacgacaatc
     4921 gaagacgaaa tcgaagaaat caaaattgat acgcaagtct tagtggcaca agaagacgta
     4981 attgtcagtg tgacgcgaga aggctatgtg aagcgaacaa gccttcgttc ttatagtgct
     5041 tccaaaccag aagaaatcgg gatgcgagaa ggcgactact tgctatactc aggtgaattg
     5101 agtacattgg accatgttct tctgatcaca aataaagcaa atgtgatcta ccgccctgtc
     5161 catgaactac ccgatttgaa atggaaagat gctggtgagc acatttctca aacaatctcc
     5221 aatctgtctg tagacgaatc gattttagct gttttcccat atcaaaaaat tcaagcagag
     5281 aaaacatttg tattcatcag caagaatgga ttgatcaagc aaacacgaat gacagagttc
     5341 gaaccatggc gcacctataa gagccgtccg ctcagctgta tgaagctaaa ggcggaagaa
     5401 gatgaactga ttgctgtgta tctgaaagaa gatcagccag gcttagatgt tttcttagta
     5461 acgcatcaag gaatgggttt gcgctatcct ttaacagatg ttcccgttgt tggagcaaag
     5521 gcagctggag tgaagtctat gaatttgaaa gatggagata ggattatcaa cgggctgctt
     5581 gtgttagcag aaggtgatac gccgatcgta atcgttactc agcgaggagc tgttaaacgc
     5641 atgcttgctc aagaaatcag ccaaacttca cgtgcgaagc ggggagtgac ggtcatgcgt
     5701 gagctgaaaa aaaatccgca ccgtattatc tatatgtcgg aaggaagatc aaaagaaata
     5761 accttgatga atcaaaaagg gcagcagtta acgattgacc caactgattt ccctataggt
     5821 gatcgaacat cgaatggatc atttgcgatg gatgagaaaa aaggtggaga agtcatcgaa
     5881 gttatcgatg ctcctgagat tttcatcgag tcgtaactgt tgtagtattt taatgaagag
     5941 acgccatctg tattaataca ggtggcgtct ctttttcatt catttttaat aaatccttat
     6001 acgtttgcaa aaaaagatga aagtgttcac aatgcttaaa tgttggtatg tcaacgttga
     6061 tttaaatata tgtaaataaa acataaaaat tgttaaataa aaaacaagaa aacccttgca
     6121 aagatagggt gctgtgttat actaatcacg taaaaactgt tacataaaac agaaatttag
     6181 gaggtccata caatggagca atggaatgga tttaaaggta ccaaatggaa agaaggcgta
     6241 gacactagag actttattca aaataactac actgaatatc gcggtgatga cagctttttg
     6301 gaaggcccaa cagaagcaac agaaaaatta tgggatgaat tgcaaaagtt aaatgatatc
     6361 caattcgagc gtaacggtgt ctatgatatg gacacagaaa tcgtatcaac tattacttca
     6421 cacgatgcag gctatttgga taaagatttg gaaaaaatcg tcggtctaca gacagacaaa
     6481 cctttgaaac aagcattcat gccgttcggc ggaatcaata tggctaacaa tgcgctaaaa
     6541 agcaatggct atacaccaaa cgatgaattg acacatattt tcactgactg gcgcaaaaca
     6601 cataatcaag gtgtatttga cgcttatact gctgaaatgc gtgctgctcg taaaaacaaa
     6661 atcattacag ggcttccaga cgcttacggt cgcggacgta tcatcggtga ctatcgtcgt
     6721 gtggcattgt atggaatcga ctatttgatg gaacaaaaga aaaaagatca tgatatgact
     6781 ggttatcata caatgagtga agaagtgatt cgtttacgtg aagaaatcac tgaacaatat
     6841 cgtgcattag cgcaaatgaa agaaatggct gcgaaatatg gctatgatat ttctaaacca
     6901 gctgcaaatg caaaagaagc tgtccaatgg ctatacttcg gatatttagc agcaatcaaa
     6961 tcacaaaatg gtgctgcgat gtcaatcgga cgtatctcag cattccttga tatctatatc
     7021 caacgtgatt tggataatgg agtaatcaca gaaaaagaag cacaagaatt gatcgaccac
     7081 ttagtaatga aattacgtat ggtcaaattc gcgcgtacac ctgaatataa ccaattattc
     7141 tcaggattcc ctatctgggc tactttatcc attgcaggta tgggattaga tggtcgttca
     7201 ttagttacaa agaatgattt ccgtctgctt catacattaa caaatatggg accttcacca
     7261 gaaccaaact tgactgtttt gtattctgaa caccttccag aaggattcag aacatatgct
     7321 agcagaatcg ctatcgaaag ttcttcgatt caattcgaaa atgataatca gcttcgtgaa
     7381 caatggggtt ctgatgattg tgcgattgct tgctgtgtat caggaacagt tgtcggaaaa
     7441 gacatgcaat tctttggcgc tcgtgctaac ttggctaaaa cactattata tgccatcaat
     7501 ggcggagtcg atgaagtgac tggcgcccaa gttggaccag aatatcgtcc aatcacatca
     7561 gaaatactag actttgaaga agtgaaacat aacttcatga atatgatgga ttggttagca
     7621 gaactatatg tcaatacgtt gaacatcatt cattatatgc atgataaata ttcttatgaa
     7681 gcagctcagc tggctttgat ggattctgac ttgcaacgca catttgctac aggtattgct
     7741 gggatctctc atgcggcaga cagcttgtca gcgatcaaat atgcaaaagt aaaagcaatc
     7801 cgtaatgaaa aaggaatagc agttgatttt gaagtggatg gcgacttccc taaatacgga
     7861 aatgatgatg accgtgcaga tgaattagtt tcatggatct tggaatactt catgggacaa
     7921 atcaaacgtc ataaaactta ccgcaactca aaaccaacaa cttcattatt gacgattact
     7981 tcaaatgttg tttacggtaa aaatacagga aatactcctg atggccgtga agctggaaaa
     8041 ccacttgcgc caggagcaaa tccaagttac aatgcggaac aaagtgggtt attagctagc
     8101 ctgaactcaa cagctaaaat gaattacggc tgtgcattgg atggaatttc aaatacccaa
     8161 acaatcaatc cttcaggtct tggaaaagaa caagatacaa gaatcgaaaa cttgcgtaat
     8221 gtcttagatg gatacttctc aaaaggagct tatcatttga atgtcaatgt attcagtaat
     8281 gatttattgc gtgatgcaat ggaaaatcca atgaaatatc cgaacttgac gatccgggta
     8341 tctggttatg cagttaaatt ccgtgacttg acaagagaac aacaattaga tgtcttgatg
     8401 agaacttcac acgacagaat gtaaaaagtt cgtgaaaaaa gtttttcgac ttagcgtcga
     8461 aaggacgttg aatagccatc gcatcaaaat cgaataatca gtatgcttat ttgaaagaaa
     8521 cgatttacag gggcaggact tgtatgttcc gtccctgtaa attttacaca taacgaagcg
     8581 gcaattgcga aaaattttgt tcagaaagct tcgcttcgac agctaacttg tacttaaaat
     8641 gaaatcaaag aaaagatgtg aacttaaatg gaagaaaaaa caatcggcta tgttcattct
     8701 atcgaaactt tcggttcagt agacggacct ggactgcgct ttgtcgtgtt tatgcaagga
     8761 tgccgcatgc gttgccaatt ttgtcacaat ccagatactt ggaatattgg cggagggaaa
     8821 gaatacacag cagatgaact tttagataaa gcagaacgct tcagacctta ctggggagat
     8881 aaaggtggta ttactgttag tggtggagaa cctctattgc agatcgattt tttgatcgaa
     8941 ctatttaaaa aagcaaaaga gcggaagatg catactacat tggatacatg cggaaaacct
     9001 tttacgtatg aagaaccttt cttttcacgt tttcaagaat tgatgaagta tacagattta
     9061 ctgttatttg acatcaaaca catcgataat gaagagcata aaaaactaac gcattgggac
     9121 aatgaaaata ttttagaaat ggctcaatat ttgtcaaaaa tcaacaaacc ggtttggatt
     9181 cgccatgtac tagttcctga gcgaagtgat tatgatgaat atttgatccg actagacaac
     9241 tttattcaaa ccttgtcaaa tgtagacaga gtagagattc ttccttatca tacgatggga
     9301 aaatacaagt gggaaacact tggtttgaaa tatccattag aagggatcga accacctaca
     9361 aaagaacgtg tcgaaaatgc taaacgattg cttcatacag aagagtatac aaaatattta
     9421 acgcgatagg tcgcatcgga aagaagataa gtattgcttc tttccgtttt tttgctatta
     9481 ttaaatagga gaaatcacaa aggagcgaat gacatgtcaa aaattttagt ttttggtcac
     9541 caaaatccag atacagatgc aatcggggca gccattgcgt tttcacactt gcaaaatgaa
     9601 ttaggtaaag aaacagaagc agttgctcta ggtacaccta atgaagaaac acaatacgca
     9661 ttagaccact ttcagctatc tgcaccacga gtagtagagt cagctaaagc agaaaatgca
     9721 gatgtcatgc ttgtggatca taatgaattc caacaaagta tttcagatat cagcgaagta
     9781 aatattttag ctgtagtaga ccaccatcgt attgcaaact ttgaaacagc taatccattg
     9841 tactatcgtg cagaaccagt tggatgtaca agtacgatta ttttaaaact atataaagaa
     9901 aaccaagtaa caattcctaa agaaatcgca ggaatcatgc tctcagctat catttcagat
     9961 acattgttgt tcaaatcacc aacatgtacg cctgaagatg aagcagctgc aaaagaactt
    10021 gcagcaatcg ctgaagtcga tctaaacact tatggacttg aaatgttgaa agcaggaaca
    10081 aatctaagtg ataaatcagc tgcggttctt cttgatttgg atgcaaaaag tttcccaatg
    10141 ggcagttcca acgttcgtat cgctcaagtc aatacagtgg accttaatga agtgatggat
    10201 cgacaagcag agctagaagc agcaatggaa gatgaaatga aagcaaatgg ctacgatctg
    10261 ttcgtattag ttgtcacaaa catcttagac agtgattcag aattacttgt tgctggtaaa
    10321 ggaaaagaaa aagtagaaga agctttccaa acaactttga ccaacaaccg tgctttgctt
    10381 aaaggtgtcg tttcacgtaa aaaacaagtc gtacctcaat tgacggctgt atttagctaa
    10441 tcaaatggta gtatgaagca ttcaaaatga atggataagc gattgatata aaaagaaaca
    10501 tagaacatac taaaggccga agaaatggag gagaataaca gtcaattatg actcttgttc
    10561 ttcctccttt ttacgtaaaa gccttttaag taaaataaaa cggatagaaa agagaacata
    10621 tatgaactat tattcaaaaa ataaggaaaa cttttatcaa aaactgaccg atgatccgct
    10681 tttttcttca ttgaccgatt atctatatga acatcgagaa caagaaacga ttctaagaga
    10741 attgaaaaaa gaattttcgc aaaataaatt ttcccatttt cttgatttat tgatcgatgc
    10801 aggattaatc aagagggaag aacgaagata tcatttgaac tttccaatat ttgatcctaa
    10861 agattacttg caacaagcca cttcggctgc tgaaaccata gctgaacaat tgaagagact
    10921 ctctgttgat gaacaaaaat tagcgatggg agaagttatt tgggcgtatt gtttcgaaga
    10981 tgaacggaaa gaagcgtatt tttatggagt aagaaacagc cgagagacag aattgctgag
    11041 gacaactgca ggaaatgaga agtaccgttt tatcacactt tcctctatag aacacttccc
    11101 gcttactttg gctaattact tttttgtaca gaagaatcag cttcctgtaa cgaaggcatt
    11161 caaagaatta gccgaactta ttggagacgt aaatgaatcg tacttttttg atcaaataga
    11221 agttatcgtt gacaggatac gtaagaataa atataaaaat cgccggccta gtattttcca
    11281 tcagtctcta cttgtgacga atactataaa ggaagaagaa tcattcacat tagaattacc
    11341 tattgtcgaa aaaaacaatt ttgagattga attaccaaca ttggatcctt cattgacaat
    11401 ggaggaaatg gcctttctta aacgacaaat cttttctgag ctgagcaaga aatttatacc
    11461 gcatgcattt tcttatatca aagaatatgg aacagtttta gtgagtaaaa cctaagagag
    11521 cagtaagcaa aaattatact gactcttgca ggaggagcct ttctcttcct ttatggttaa
    11581 aagaattatt tgagtatttt gcctatctac cacctattag attcactaca tggtctggaa
    11641 acaaaggaat gcaaaaaaat ggtgagaaat gtggaatgac aaaggaagta gtgataagaa
    11701 aagttagatt tttaaataat caatattatg attcagtcaa gtatggcatt ttatgggaag
    11761 aactagctga ttagattagg aagtccattt gataatccag aatcactaag aaacgaatgg
    11821 cgagtcatta ataatttatc caatcttggg ttattctttt agattgaagt gtttaaaact
    11881 aaaaaagcat ttatgaagtc gtaatagtca ggcttcaaaa tgctttttat tttgtttgtt
    11941 ttttctttgc cacataaata cacctagact gacgatgaag agcatatcca acagatttcc
    12001 tgcgacttgg atcgtcgaag ggttggtcag tggcattaaa gcaaggacaa aaaaggaaaa
    12061 caagctgtaa ataaaacagg tgacaggaac taatcgaaag aagagcggac atttcaattg
    12121 gctaaaaatg agtgaaaaaa taaaataagt aaaaatggat aaaatcacga ctaaaccatt
    12181 catgataaag aagaaaagcg tattgtgatt aaacgaataa aaaagaattg ctaaaaaaga
    12241 aaacgtttta aatgcaatca atacgcttga agcttcgttt aacgtaccag gatgtcgatg
    12301 aaaaaaatag gcaccgaaat aaacagaaaa cagtaagccg caaagagaag acaaaatcaa
    12361 aaaaaacgga ttttcttcgg cttctgtgat atcagaatga tccaaaagca accagcctaa
    12421 tgcactagaa ggcgcatgtg aggtcttaag gtatgaataa catagaaaaa ataagatcgt
    12481 caaagttgca aaaaaagagc ctaaatgtaa aaaattagtg gttctacgtt gaatttccat
    12541 aatatctcca aattaaattg ataagtatat aaagtataat aacaaattga tgagtatatg
    12601 tcgatgtttt ttaatcaaaa taataaataa aaactgtcta acatttaaaa tttaatttag
    12661 atattagaca gtttttaagt ttgtgagtta ttttccttgt cgttttctca cttttttagt
    12721 ccagaaacca cctgaaatat attttggctc ataagaaatg ataaaagcac gctcttcgat
    12781 ttctttgatc aggcgataca gttcacgttc gctttttcta ggagaaagta tttcgagaac
    12841 tagccgctca ccttccagcc ccattgcaga agtctgtgtc acaccataac cgtgttctct
    12901 cagtataccc ggcaaacttt tatcttctgc gctatttgct ggcaaaatcg ttgtgaccat
    12961 gatgtatcct aatgccaatt tgtcttcaat caaaattccg acactgatac ctactgcgta
    13021 acctaacgca tagacaaata aattcagtgg attatctaaa cgatctaaaa caagggataa
    13081 gccgacgata taaatcgtga tctcgaccat actgacaagt ggagcaatca gtcgatagcc
    13141 tttcattgtc aacatgaaac gtaacgtgtt cagagtgata taagcaaaat taatgaggaa
    13201 gatcatcccc aacatttttg gatcaatcat ttgtaaaact cctttcattt atataacaac
    13261 aatatcaaaa aaaatcgcaa gtgaagaaaa attgaaactt tatacataca aaaaaatgat
    13321 aaaatgatta taatagaatt ataaagatag gttaggtgat taaaatgaaa acggtcaatc
    13381 gtgtgttttg tgccagccac gtgctaagtc tccttctcag tatatactta ggtgtctatt
    13441 cgattcaaca gccaattgag gtagagaaca ttgtttttca gatgtcgctg acagatggtt
    13501 taattttaag cgtttttttc tttttgatac tgtttattgg taatattttc ggtagcgttg
    13561 ccagtttttt gaatttttct atttatccac tcctttcgct agcattagga gtggtgggac
    13621 tttgttctct gtgcttattt cccgagccat tcagtcctgc atttatatta tttggtacac
    13681 tgaacctgtt ccagacaact gttggagcat ggttgctatg gcgatcagga aatttaatga
    13741 aaataggtga gtaacaattg aatccaatta tattgaaacg ttctgtccat catattccag
    13801 tgttagaagt tgttctgaaa gaattaagag aggaacgtat tcccgttgtc atctattatc
    13861 acggatggca gacaagtaag gagttagttt tgacgcaagg aagaaaaatt gcgcagcagg
    13921 gcattcgtgt gatcctgcca gatgcgatga atcatgggga gcgcaaacag ccggtttctt
    13981 ctattccatc ctatacattt tgggatagta tctacggaaa tctgtttgaa tttgacacac
    14041 ttatcaagca tttagaaaaa agaggtcttc tacatgatca gcttgcagtt ggcggggttt
    14101 cgatgggggg aatgacaaca tgcgccttgt tggctaaaca tcctcatata gtagcgggcg
    14161 tgtgtttgat gggttcccct gcacctttgg aatatggaaa agaaatcgta aggcgcgcat
    14221 cggaatataa ttatgtcgta ccaaaagact attttgattt gatttcatgg gttaagagct
    14281 atgatttgtc attgcagccg gaaaagttag ctggacgtcc tctgttcttt tggcatggac
    14341 aagctgacga aaaaatccct tatatacaaa cggaacgatt tgtagaaaaa aatcggcata
    14401 agtcttacgg aaaagaaatt gtttttcgtt cctcaaaaac acagcgacat atggtacaaa
    14461 taccactaat ggaagaagct tccacttttt tagcaaaaaa tttgataaaa aagtataaat
    14521 aattgaaacg gaaaatcact catgacgata gaggattttc cgttttttat tttgggctat
    14581 aataaactct gttaggaaaa tttggtataa ttgatagtaa gaatgacaac atgttagaaa
    14641 ggaagagagc atgcccactt tagcagatgt tgcaaaacgt gccaatgttt caaaaatgac
    14701 ggtctctcga gtcatcaatc atccggaaca ggtgactgac gaattgaaag agttagtttt
    14761 ctcagcaatg gctgaactgg attaccgtcc aaatattgct gcaaaagcac ttgtcacgaa
    14821 tcggtcgcag atcatcaaat tatttatact ggaagaaatc gacacaactg agccctatta
    14881 catgaatttg ctgatgggaa tcgctaaacg gatcggtaaa gcgcattatt ctctccaatt
    14941 agttacaaat gatgccttcg acgtcggttc ttgtgatgga tacatcatca caggtgtcag
    15001 aaaaaaagac ttcgattgga tcgaccgttt ggaaaaacca gttgtcttgt ttggggaaaa
    15061 ttctgaagga tatgattatg tagacagcga taatgaatat ggtacagcaa aagcaacgca
    15121 atatgcctta gaaagagatt atcaaacgat tatttatatc ggtatcgaag tggacgagcc
    15181 ttttgaaatt tcaagggaaa ctggttattt atctgtgatg aaggaagttg atcttcctag
    15241 taaaatcttg cggtttccaa atcattcgac agaagtagaa agatatatga cagaaaactg
    15301 ggcagatttt acagataaaa cttgttttgt atgtagttca gatcggctag cactaggagc
    15361 agtaagaggg attataaatg ctggaggaca cttgcccgaa gaatttggtg tgattggatt
    15421 tgatggggta tttttagacc aaatcagttc acctaaattg acaacgatca agcaagatat
    15481 tatacgtatg ggtgaagtat gtggagaaat gttgttaaaa aaaatagaag aaaaaggggc
    15541 gagtcaaggt tatcgtcgtt tttttcctga actagttatc agagagacaa cgaattaagt
    15601 cttattacta tatatatatt tatgaaattc atcgctattt tcttaaaata atcagcgcat
    15661 tgctactgaa aacaatgaat ctgtgctatt attgagaaaa gttccatttt tgagaaggat
    15721 ggtttgaatg aaagaaatca gacgaaaaca tttccgtttt cctgcgtacg atgatgagtt
    15781 aggcgtaaaa ttaaccaacg acaagaagcg agtattattt gacggacaag aagatctttt
    15841 gactgaacag aatcagtccc cgtttgaaca gatgaaagaa tttcatttca cgaacacgaa
    15901 caccgagaaa atccgtcgca agcgtcgtgc aacaaatgga ttgaagtcag ctccgcgtaa
    15961 ggaaaatttg gaaaagcata aaggaaaatt accggattat accggccatt accaatcaga
    16021 aatcacatcg acaggacgaa aaaaactttt tggtgattcc tctcgttctg tcagacaaag
    16081 tgaaacaagg acagagtcca agcatactac acgaaacgca tctgttgaca cgaaggtgcg
    16141 ggagcgttct tattttgttc ctaaatatgt acccgcatcg attatcccag accctagaga
    16201 aagcaaaatt tctgaggatc atttaatcga atcgatgaaa aaaacggatg actcttatct
    16261 gttgttcgat acagaaccga cgccgtatca agaaaaaaga aatggtgagc cgtctgtacg
    16321 aacattcaat cgaacaaaaa cgttagagga aacaaagcag tcagaagaaa aaaaatcgaa
    16381 aaaaagccat ggtatcttag aacgctcatt acaaggattg atcgatgatc aaggaaactc
    16441 tttgggagaa aatagctatt ttaaataagt gatatacaaa tttatattcg gctacagttg
    16501 gaaaggaaac gctgcggcgt ttccttattt tatactctat ccgaaagttt atatcgtatc
    16561 ctcaaatttt tttgagttta agcgaatttt ttctcccaat aagtaagaaa ataatggcaa
    16621 aataaaaaaa caaactattt tcgcagatcg tttgcaaaaa tagtttattt ttttataaag
    16681 aagattttac tgaataatat cattttagtt tacataatga tatttctgta aattaaataa
    16741 agtagtgaaa aataagaatc agtgctctaa ctgttcaaga ggatcaagtg gttcaaatgt
    16801 ttctgtagtc tgttttgctt ccaattgggg caaaacagat ccaatttcca gatacttcac
    16861 tttattcaat gtataagata gaatagaaca gctaagtaat gtatacagaa aatgtgtgag
    16921 atccaaataa agcaaggaga caactaaaat accaaaagta atcaagaaaa gacttttgcc
    16981 aatcttaata tgaaaatatt tttcaatggc ttgataaatg atatctgttc cgcctgtgct
    17041 tccgccgaat cgaaagacga gaccgcaacc aatgccagaa agaatacctg tcatcaaact
    17101 attgatcagt agactatcta cagcaaaatg tatatgaagg ctctcccata aatgtaaaaa
    17161 gaaaactagc gcaaatgttc cgacgatcgt ccggagaaaa gcgtgttttc caaaaagaaa
    17221 caatgagata agcaataaag gtaaattaaa aagcagtgaa gtgacagaag gagcgaatcc
    17281 aaaaagatta tgcaaaagca aagcaatacc agtaacccca ccatctgcca gcttagatgg
    17341 aatattgatt cctgtcacag ctaatccgta gattcctgcg cctaaaatga ttccgcacaa
    17401 ttctgtaaat aaatttaatt ttttcatttc tagcctcttt tcttttgaaa attttcagca
    17461 acttctttat tatactgact tatactctta cttcaagagg aaaatgaaaa aaaattattt
    17521 ttggctgttt ctttttattt atcaaataag gagtggaaaa atgcgagcag cagacttatt
    17581 gacaattctt acaaaatcac ccaaaaaaac agagtatcaa ggagtttttt tggctcaaga
    17641 acaaaaactg gtgcctgtga caatggtcca gataaataaa gcaaatcaat ttatcttttt
    17701 atttgaacac ggcaaagcac cacttgctat gaaagacatc tttctttttt tgatgaagaa
    17761 ccgtgagaaa gctgtttatt atcagtcaaa agaagaactc attcctcttt atggagtgaa
    17821 agagatagaa aataaagtgg tgatataagt aaaaataaga aaacaagacg tttatgatgt
    17881 caaaacaacc attttttaca tttttggcaa aaaagtgtca tgatacagta taatattcgt
    17941 tgaacaggcc aataaaggtg ttctccccca cgagatttct actttattgg ctgtttcttt
    18001 ttattaaaat aaaagttgtg tgtgtaaaaa agatatagct gattccaagt gacaatttcg
    18061 tatagatttt tatggtattc gtagtgaaaa aacgagaacc aaaaagttga tccgactttg
    18121 ttgcttggat tctttttttg tcagcatatt tagaggtatt tttttctttt ttttgttcgt
    18181 gctgtaaggt taaggcaaga caagttagtt gggaaaaagg aaagaaatgt ttatacttaa
    18241 agaataacag aaaggaaggt cgcatgaata attttataca aacattaagt gaaagaaaag
    18301 gcgagttgct ggaagctgca tttcaacatc tgtccatttc tctcatttct ttgctgattg
    18361 cagcactgat tgctattcct ttagcgattt gggcagccaa tcataaaaaa atggcagaag
    18421 tcttattgca gatcacgggt gtgctccaaa cgattccttc acttgcctta ttaggtttac
    18481 ttatcccatt tgtagggatc ggaactgttc cagcattgat tgcacttgtt atttacgctt
    18541 tgcttccgat tttccaaaac acgtatattg gtctagctga aattgacccg tctattgaag
    18601 aagcagcggt agcatttggt atgtccagaa tgagacgctt gctgaaagta gagcttccca
    18661 tcgcattacc tgtcattatc tcaggtatcc gaactgcctt agttttaatc atcggtacgg
    18721 ctactttggc agcattgatc ggagcaggtg gattagggac atttattttg ttaggtattg
    18781 accgaaatac acctgttttg acattgattg gtgcgatcag ttctgccttg cttgcaatta
    18841 tattcagcgg actgattcgc tggttgcagc ataagaaacc tcgatattcc atcattactt
    18901 tagcagcagt ggtgtgttta tttggcggcg tttctttata tcagtctgcc ttgtttaaaa
    18961 atgaaaccat cacgattgct ggaaaattag gagcggaacc tgaaatcctg atccaaatgt
    19021 ataaagaatt gattgaagac aacacaaaaa cagaagttga attaaaaccg aattttggca
    19081 agacgagttt tttgttcaat gcactggatc aaggtcaaat cgatatctat cctgagttca
    19141 caggtactgt cctagaaagc ttggtgaagg tacctgaagc aatgaaaagt gctgatttga
    19201 caaaagaaaa aacatatgac gaagcagaag aattattgaa taagcaattc gatatgacat
    19261 tattaaaacc aatggcttac caaaatacgt atgccttggc agtcaagaga tcttttgcga
    19321 acgaacatca acttaaaaag atttccgatt tggcagctat ctctgatcag atcaaagcgg
    19381 gattcacact ggaatttatt gatcgttcag atggatataa aggaatccaa gaagcatatg
    19441 gcttgaattt ttcaagtgta caaagcatgg agccaagttt gcgttaccaa gcaatcaata
    19501 atggagatgt caatattgtg gatgcctatt ccacagatag ccagctcaag gagtacgatc
    19561 tagtgactct agaagatgat cgagggttat tcccagctta tcaaggcgca ccgctgatga
    19621 aaaaagattt tgctaaagaa catcctgaaa tcgttaaagc actgaataaa ttaagcggaa
    19681 aaataacaga ggatcaaatg attgatatga attaccaagt caatgtcgaa aagaaaaagc
    19741 cgacagaagt agcacgaatc ttcctgaaaa atgaaggatt agtaaaggag gaagatcagt
    19801 gactaaatta atcgagttca aacatgtgca aaaaaagtat gatggaaagt atgtcatcga
    19861 tgacctaaat ctggcaatca aaaaaggaga aatctttgtt ttggttggtc cttccggtag
    19921 tggaaaaaca actactttga aaatgatcaa tggattatct aaaccatcag caggagacat
    19981 ctacttcaaa ggaaaatcgt taaatgaata taatctgcag aaaatgcggt ggaatatggg
    20041 atatgtgctg cagcaaatcg ctttgttccc gaccatgaca gtcaagcaaa atattgaagt
    20101 catccctgaa atgttaggtt gggaaaagca gaaaagagca gaccgtgtag atgaacttct
    20161 tcaaaaagtt ggcttatctc ctgatattta tcgagatcgt atgcctagag agttgtctgg
    20221 aggagaacag caacggatcg ggatcatccg agctattgct gcaagcccag atgtgatttt
    20281 gatggacgag ccatttagcg cattagatcc gatttcaaga aactcattac aagaattggt
    20341 tttgtcctta cacgaagaat tgggcacgac catcgttttc gttacgcaca atatggaaga
    20401 agcaatcaag ctaggtgatc gtattgcatt tatgaaggat ggagaaatta tccaatgtga
    20461 cacaccagag cagttattga tgaatcctaa aaacgactac gttcggcatt tctttgatga
    20521 accgaaacag acgaaagagt ggcgagtaga agatttagtc gtcaatggat atttcttaaa
    20581 tgaaatacca gaaaatgctc gtcaacaagt ttgctttgat acgcctatga aagaagtata
    20641 ttcgcttctt tcggtgtatc caagcattgt gatagtagaa aagcaaagaa gtattgggtc
    20701 gctgacaagt aaagaaatct ttgctttttt aagtcgagag gaggaaggaa atgaaaacat
    20761 atgatgcaat catcatcggt tcaggtgtga gcggcttaag tgctgcttat ggattgaaag
    20821 aagcaggtaa aacagtacta gtggtcgaag aagatctatg gggcgggact tgtcctaacc
    20881 gtggatgtga tcctaaaaaa gtcttgttaa gtgcagtaga ggcacgtaat cgggtaaaac
    20941 aattgagtgg aaaaggtttt aacgagatcc caactgccaa ctgggaagaa cttcaaaaat
    21001 tcaaacgaac atttacggat ccagtcccag aaagccgaaa aaaacaatta gcagaagctg
    21061 aaatcgatca tctttcagga accgctcgtt ttttggatga ttcatctatt gaagtcaacg
    21121 aagaagtctt ccatgcggat tacttagttt tggcaaccgg gcaaagacct acgatcttac
    21181 cagtggaggg aaaggaatac ttgaaaacta gtgcagactt tttatcattg cctgtactgc
    21241 ctaaagaaat catttttatc ggtggtggtt atattgcttt tgagctagct acgattgcca
    21301 atgctgcagg gagcaaagta accattgtcc atcataatca acggccatta aaagaatttg
    21361 aggcgtcttt ggtagaggaa gccgtccatc aaatggaagc atctggcatt cagtttgctt
    21421 ttggtgttga aacccaaaag atcatttcag aaggtactcg ctatcgttta gtcggaaaag
    21481 agacggaatt agtagcagat atgatttttt gtgcgactgg gagacagccg aatacagaat
    21541 ctttagcact tgagcaagcg aatatcgtct ttgataaaca cggaattgca gtcaatgatt
    21601 atctgcaaac gagcaatcca aaaatttttg cgtgtggaga tattgtttca aggaaaaccc
    21661 caaaattgac accagtcgcc acttttgaag gaaattatgt agctaagcgg ataacggatg
    21721 caacaagcga acctatcaaa tatccgatta tacctacgat cgtctacgcc agtcctaaac
    21781 ttgctgaagt aggagttaca aaaagtcacg cctcttcgtc agatcaagtg gtagagatgg
    21841 atcttaccag ttggttcacc tatcatcgtg tcaatgaacc agttgctaag gctgaattga
    21901 cctttgacca gcaaaattat ttgattggtg ctgcagtgat tagcgagcaa gcagacgaat
    21961 tgatcgatga tttgacactc gtcatcaatc aaaaattgac taaaaaagag ttggatagct
    22021 atatcatggg gtatccgaca ttggcaagtg atctctccta tttattgaaa taatcagcat
    22081 gataactaaa gcgcttgttg ctttttcctt cttgtgctac actttaaaaa atgaatacct
    22141 gtttctgggg atgtcgtaga cgacatgaga gtaagttgtg aacttagacc cattgaacct
    22201 gtcagttaat actggtgaag ggagaaacat agcagacgct tgaagcgggt tactatgtcg
    22261 tgcccatttc aagcgttttt tgttattcat attagaagaa aggaggtaac aaaatgaaga
    22321 aaaatcttta tccagcagtc agtatggcat tcattttaat tatttggcag attgttgtca
    22381 tagtttggaa aatacctgcc tttattttac ccggacctgc tgctgtattt tctgcattag
    22441 cggcagatgc acaagtatta ctttcccatt ctgtcacgac attaaatgaa gcagtgcttg
    22501 gtttggtaat agctagcgtt ctttctttta ttactgcctt ggcaatggat tattggaagt
    22561 ttttagaaat gtctttttat ccgttactag tgatttcaca aatgttgcca atcatggtgt
    22621 tagggccatt acttacccta tggtttggtt tcggtatgct tccaaaagtg atccttgttg
    22681 tcttgataag ctattttccg atcgtagttt ctttttcgga tacattgagg aaagtatcaa
    22741 aagagcaaat catctttttg aaaacgatgg gggcagatac agggaagatt tatcgaatat
    22801 ataaaatacc agcgggttta tccggcttct tttccggttt aaaagtggct gctacttatt
    22861 gtgtcagcgg agcagtcgtt ggagaatggc taagcgctca agcaggctta gggtattaca
    22921 tgatacgcgt aaaaaacagc taccagatcg ataaagtttt tgctgcgatc atttgtgtca
    22981 ttctattgag tttattgctg aatggcgctt gttcattatt gaaaaaaggg tattatcgta
    23041 tgctttatat tttttaagag aaggggatca aatgaaaaaa ttatggcttt tattaccgct
    23101 actgttgctt ttatccgctt gtggcactgc aaaagaaaca agtagcaaac aagaaataaa
    23161 ggatttgaaa aaagtgacac ttgttttgga ttatgtaccg aatactaatc atactggcat
    23221 ctacctagca aaagaaaaag gctattataa agaggctggt ttaaatgtcc aaatcatcga
    23281 accaggagat aattcgacaa gtattggtct agtaggtgcg gacaaagcac aatttggtgt
    23341 aagttatcaa gaagatgtca cttatgctca cgcagatgga cagaatatac cagtcaaagc
    23401 aattgctaca gtgatcaaac ataatacttc tggattcgcc accctatcag acagtaacat
    23461 ccattcacca aaagattttg aaggaaaaac atatgcaggt tggcaaagtc caagtgaaga
    23521 agctgtctta aaagctgtga tggaaaaaga cggcggggac ttttcaaaac tgacaatggt
    23581 aggaagcaat ggagaagggc cagaaagctt aggaaaatcc tcagatatcc aatggtactt
    23641 tgaaggttgg gatatgatca aagcaaaaga agcgggtatt gaactaaact atatcccatt
    23701 gaaagaatta gatgaacggt tagattacta tactccggta attattacga atgatcaact
    23761 gatcaaaagt gatccagaat tggtacagtc ttttatggat gccacgaaaa aaggctatca
    23821 ggaagctatt aaggatccaa atgacagtgc taaactgttg caaaaatatg caaaagaaaa
    23881 tgatcggacg tttttagaag aatcacaagc attcttgtca aaaaattata cggatgatcc
    23941 tgagaattgg ggattgatgg aagaaaaagt ttggcgcaat tatacagctt ttatgcagga
    24001 aaacggattg atcaagcaag atgtaccttc gcaagaacta ttcactaatc agtttataaa
    24061 ataggagtga tagatatgtc aatccaaatc agccacttga atgtagtcat tgaaaacctg
    24121 aaaatattag aagacatcca tttcactatc cctaaagata cctttacatc gattgtcgcg
    24181 ccaagcggag ccggtaagtc aacattgctg aaaactttaa caggagtcca gcctatgact
    24241 tctggaacga tcaaagtaga cgatcaaaaa gtaactggtc tccatacagc atttagttat
    24301 atgccgcaag aagatatgtt acttccttgg ctgagcgtct atcaaaacgt tacgttatat
    24361 caaaaaatca atcatctaac aatcaatgaa gaacaagtaa gggattatct ggatatcttt
    24421 gggttaaacg gctatgaaca ttttttgccg gaacaattat ctggcgggat gaagcagcga
    24481 acggccttgt tacgaacaat catgaatcct tcttcttact tgcttcttga tgaaccattt
    24541 ggagcgttag atgctatgac cagagggcag atgcaagact ggatgttgaa gctgcctaaa
    24601 aaagcaaagc ggactacttt acttgtgacg catgatatcg aagaagcaat ttatttatca
    24661 gacaggattc ttgtgctttc cgcccgtccg gcacatgtga ttgctgagat tcaagtgcct
    24721 gaaaaacgac ggtcacgtga atggctactg cagcaatcag agttgaagca aacgatttat
    24781 cagttattgg caggtgaatt agatgttaag tgatgctcat tgtcatttag atgggagtca
    24841 gagtttagca ctccttcagc aggaacacac gattttgacg atcatcaatt gtgattcgcc
    24901 agaagaatgg aaggaaaaca gacagcttgc agcaagtaag actcaagcct taagttacgg
    24961 tatccatcct tggaaagcag atagctatac gtttgaacaa gttgagcctt ttttgaaaaa
    25021 agcaaggatc atcggtgaaa tagggttaga taatatttgg acgaatgtac cgatgactac
    25081 acaaaaaaaa gtatttgagc gacagcttgc ttttgcagcc ataaatgaga aacctgttgt
    25141 actgcacaca aaaggatgcg aaaaagagat cttaaattat atccaagctt accctaatca
    25201 ctatttgatc cattggtatt cttctttgga ctatcaacaa gactatattg atttaggctg
    25261 ttatttcagc attggtcttg atttgaaaaa gaatccagca gtctggcaac tagctaaagc
    25321 agtcccaatc gaccacttac ttattgaaac ggatggacta catgcagcag agtgggcttt
    25381 aggggggatt ttttcagaaa aagattatgt ctcactgctt gaagaacagt taaagacaat
    25441 cgctgagatc aaagagctat cagttgaaga agttaaaaaa aatacttatc aaaacttgga
    25501 acgtttcatt agattaggta aataaaaaag agatgtgaca caactagtgt cgcacctctt
    25561 tttggctttc tttgtataaa agtaaactgt ttgattaata aatgaatctt agtaccaacc
    25621 gtttgcttcc cagaatgctt tcgccgcttc ccaagaacca taacgtgaag taacatattg
    25681 ttctgctact ctttcttggt ttgcagcaga gtagtcacca tttaagtaag aagaatctaa
    25741 ttggtaacgt ccgatgtaac gtccgttcgt tgctgtgtaa gaaccgcttg attctttttg
    25801 tgcgatccat tcttttgcag agcttgtgct tgctggagta gcagcagttt ctgttacagc
    25861 aggagcaggt tgtgtttcag caacaggcgc tgcttgtttt tccgtttgaa ccgtttcttg
    25921 tacaacaggt tgttcagctt ggactggtgc ttcttgaacg gctgcttgag gttcagcagc
    25981 tgcttgtgca gagccttctg ttgggattgt taattgttgt cctgagtaaa tcaggttaat
    26041 atcagaaatt gaatttgatt ctgcaatggc attgatcaag gagttatcac caacgtattt
    26101 ttgagaaatc gttgatagag tatcacctga ttgaacggta taagcttcgt ccgcatgagc
    26161 agtcgttccc atgaagaatg cagcgccggc agccaaagtt gttccaaaaa gtaaagtttt
    26221 aagtgatgtc atgaaaaatc tcctttattc gttaaaaagt tttatttgtt gtgttcaacg
    26281 aggaatactt taacacgtga aaatatttca taggtaaaag aagcatgaca atttatgaca
    26341 aatccgcgtt ttttgtaata aatacagtaa tctatgaaat gaaaagggtt acgtttaata
    26401 aaacttgctt ttttgttttt gttcaccata aatatttatt taagaaagta ttaacctgca
    26461 tttttctcta taaaaaagat tttttaaata gataaaaaag gaggattaaa tgagtatttg
    26521 atagtattta tattaaaatt acatatgtaa tttaaaaacg cttgacattg tgtttgagat
    26581 cacttacttt tagcatgtaa aagtattgga ttaaggagct atgcaaatga aaaagaaatt
    26641 tattactggt gggattgtcg ttgcatttct atgtctaatt ggctacacag gcacgcggta
    26701 cgcaaatgaa attattttgt ggggtggaga gacagatatt gatacaatca atgagaatct
    26761 gacacagctt gatcatacat tgacagataa agagcaagcg attacagatc ttaccgctcg
    26821 actagcacaa aaagaacaga cattgcaaga ttcaaaggca gatgtccaag aataccaaac
    26881 aaaagtaaat gaattagaaa accaaaaaaa tcaatcggca gcagaaaaac aaaacttaga
    26941 aagtcaatta gtcagcaagg atgcacaact acaaagcaaa caaaatgaaa tcaatgtcaa
    27001 actagatgag atcaaccaaa aaaatgatga aatcaatcat ctgaatgcag attggacagc
    27061 aagactacaa gaagcacaag caaaactttc agaattacaa aatactgtaa atggtttgaa
    27121 tcaacaaatc gcaacactga cacaagaaaa aacaaatgta gaaatcagtt aacagataca
    27181 caaaagaaat tagacgaagc aactgctgaa aactcaagct tgaaacaata tattcaaaag
    27241 ttagaaaaag caaaagatga agtggaagat acagctgata aatctcagca aattgttgaa
    27301 gaacatttgc gtaaataatc tttcttaaca agtaaaccta aattagtaaa gaagcaacag
    27361 taatctatac tgctgcctct tttttttagt acatgtcctt catcttcgca ggaagtgcca
    27421 atatgatttt aagaaaggta atagacaaaa agtcaaaaag ataaaacaga gtttcttctt
    27481 tacaaaggga atgtatgttc gtataatggt attgaggtga aggttatgga gaaaaaatat
    27541 ggaacagtag ataagatccg tactttgcaa gttagtgcca gaccgttgat ccgtttcagt
    27601 ttaaatgggg tcaattgttt gattgcttcc catagtttga acttcctagc tgaagtagac
    27661 gaagggatga agttagtcgt tacaggttat tataataata gaaagcaatt tgttgtgaga
    27721 tcctatcatg tgttagggaa acccaaaatt gtggtagaat atgagaaaag tctataccca
    27781 agaaaaaagg tccgacaaga tgaaagaata aactagaaaa caagcggctg agacaaaaat
    27841 gtcctagccg cttgttttgg aaagatggat gcagacgatg ggatttgaac ccacacgagc
    27901 atacgctcac aagaacctca atctatatat aactacatgt atttaagtat ttgtgatgaa
    27961 tcactaaact ttccaaactc atttgaggga tattgcttaa agattgaaca gatcaattcg
    28021 aagccctatt agtattcgct caatgggggg atcagaggcc ataaaaagag actagtcatt
    28081 actagtctca ggtagtggaa ttgtaggatt ttaaacgttc ctggagagta ccggtatgta
    28141 actcgaagag gtgattatca tagtcgtaaa agtaaattga agaagcctcg cctttcacac
    28201 gagaacgtcc tggttcgaca gttaaaccta acatttggat ttttgagaca aacgaatcta
    28261 tatcttgttc gtcaatttta aaagcaatat gattgtatgt ctttggcagt ttattcgacg
    28321 aattctgcat tactgcaatc cataggtcct taactaagaa aaatttttct ggatataatg
    28381 aaaatttttt tgttgactat cgtagatttc ttttgcatca aataaggtat ttaacaatta
    28441 agtatttaaa agataacttt taagttatct ttaagtaatg cttaaagcta tgttatactc
    28501 tattaggaaa tataagaagg agtataaaaa tgaacaaaca taatagaaaa ataacgaata
    28561 acaaagaact gatcttgtta ctaataggga tttggggtat ctttttactc tttaatatgt
    28621 atatgccgac tatgagagcg gatgacgtag tttatgcaag tagattagat gaacttggct
    28681 atttgggtgc ttcgatagaa cattataaga catggagttc aagaattatt atagaactat
    28741 tcttaatgtt cttttctaaa cactttatgc tatggaaatt attaaattct acgattatgt
    28801 taggaattgt agtattactt tgcaagtat
//
LOCUS       DAFEKH010000036        27929 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.037, whole genome shotgun sequence.
ACCESSION   DAFEKH010000036
VERSION     DAFEKH010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27929
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.037"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(117..938)
                     /locus_tag="LP386_001778"
     CDS             complement(117..938)
                     /locus_tag="LP386_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBL1919013.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(1035..1313)
                     /locus_tag="LP386_001779"
     CDS             complement(1035..1313)
                     /locus_tag="LP386_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919014.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            1581..3590
                     /gene="metG"
                     /locus_tag="LP386_001780"
     CDS             1581..3590
                     /gene="metG"
                     /locus_tag="LP386_001780"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HBL1919015.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(4069..4656)
                     /locus_tag="LP386_001781"
     CDS             complement(4069..4656)
                     /locus_tag="LP386_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919016.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            4831..6153
                     /locus_tag="LP386_001782"
     CDS             4831..6153
                     /locus_tag="LP386_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1919017.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            6308..7084
                     /locus_tag="LP386_001783"
     CDS             6308..7084
                     /locus_tag="LP386_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBL1919018.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            7077..7646
                     /gene="rnmV"
                     /locus_tag="LP386_001784"
     CDS             7077..7646
                     /gene="rnmV"
                     /locus_tag="LP386_001784"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HBL1919019.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            7639..8523
                     /gene="rsmA"
                     /locus_tag="LP386_001785"
     CDS             7639..8523
                     /gene="rsmA"
                     /locus_tag="LP386_001785"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HBL1919020.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            8974..9603
                     /locus_tag="LP386_001786"
     CDS             8974..9603
                     /locus_tag="LP386_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919021.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(9727..10836)
                     /gene="ugpC"
                     /locus_tag="LP386_001787"
     CDS             complement(9727..10836)
                     /gene="ugpC"
                     /locus_tag="LP386_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HBL1919022.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            11045..11467
                     /gene="mgsA"
                     /locus_tag="LP386_001788"
     CDS             11045..11467
                     /gene="mgsA"
                     /locus_tag="LP386_001788"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HBL1919023.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            11790..12326
                     /locus_tag="LP386_001789"
     CDS             11790..12326
                     /locus_tag="LP386_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBL1919024.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(12366..14129)
                     /locus_tag="LP386_001790"
     CDS             complement(12366..14129)
                     /locus_tag="LP386_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1919025.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(14132..15847)
                     /locus_tag="LP386_001791"
     CDS             complement(14132..15847)
                     /locus_tag="LP386_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1919026.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(16626..16850)
                     /locus_tag="LP386_001792"
     CDS             complement(16626..16850)
                     /locus_tag="LP386_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919027.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            17041..19818
                     /locus_tag="LP386_001793"
     CDS             17041..19818
                     /locus_tag="LP386_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL1919028.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            19899..20318
                     /locus_tag="LP386_001794"
     CDS             19899..20318
                     /locus_tag="LP386_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HBL1919029.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            20330..20800
                     /locus_tag="LP386_001795"
     CDS             20330..20800
                     /locus_tag="LP386_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1919030.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            20817..21596
                     /locus_tag="LP386_001796"
     CDS             20817..21596
                     /locus_tag="LP386_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL1919031.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            21583..22404
                     /locus_tag="LP386_001797"
     CDS             21583..22404
                     /locus_tag="LP386_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL1919032.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            22421..23470
                     /locus_tag="LP386_001798"
     CDS             22421..23470
                     /locus_tag="LP386_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL1919033.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            23483..24487
                     /locus_tag="LP386_001799"
     CDS             23483..24487
                     /locus_tag="LP386_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL1919034.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            25120..26139
                     /locus_tag="LP386_001800"
     CDS             25120..26139
                     /locus_tag="LP386_001800"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBL1919035.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            26182..27063
                     /gene="galU"
                     /locus_tag="LP386_001801"
     CDS             26182..27063
                     /gene="galU"
                     /locus_tag="LP386_001801"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBL1919036.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            27363..27740
                     /locus_tag="LP386_001802"
     CDS             27363..27740
                     /locus_tag="LP386_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919037.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
BASE COUNT         9117 a         4864 c         5715 g         8233 t
ORIGIN      
        1 ttttattcag aaagtttacg aatacatcaa aattctgaaa caaaaaacgt aactcacaaa
       61 gagttgtttt tgcgtttttt cttgaatgat taggtctgaa tcttttgctc acaaccttat
      121 tcatggtgcc ccggcttgag ctgatagatt tttgaaggac ggccgattcc tacaggacgt
      181 tcaccgatct catcgaaata ttggagcata gctttcttaa aattggaatg atcgatcgtt
      241 ttataatcga tccctaagaa tttagcaaat acttttcgag cttccgtaat cgtgaaatct
      301 ttacctaaaa cttgtagaac ttgcggctcg tgttccattt tattgactac acggttgaat
      361 gctttcaaga tgatttgact atggtcaaaa gccaaagtat ctttgccaga agactctcca
      421 gtgactaaat caagcgagat agccacttct ccgctagata aatggatctt gttactatga
      481 cgttctagtg tgaaccagcg tacttccttg gcatcatctc cggcgattag cggttcttct
      541 ccaataaagg ctaagtagct gactgtgacg acccagcctc gcggatctcg attaggcgta
      601 ctgaatgtat gcagttgctc aatattttct tttgaaataa ccacaccagt ttcttccttt
      661 gtttctctta agacgctttc tccagttgac tcatcctttt ggacaaagcc accaggcaat
      721 gcccatgaat ttcgataagg atgccctttt ctttggatca acaaaacttt cagctgatct
      781 tcttctttgt tatagcacat cagtacgata tcgacagtca aagagggctt gtcatattct
      841 ggacgttcct gtttttgata ccagttaaga aattcttctt cacttgcttt atgttcataa
      901 tataattttt cttcttcttt agaagcaaaa cggttcatct gaccacctcc attgacagta
      961 aaagtacttt ttaccttatt gtagcagact ctgaaaaaaa accaaggatt tacttgaaaa
     1021 atctaggtta tcatttaaat atgaaaaata aatggaagta tgagattgaa taaaaagaaa
     1081 agcagataaa acggcaatac tttataccgc tcttcacgaa tggcaaagaa gccacaaata
     1141 acgatatata cgtcaatgat aaaacgcaaa atccaagctg ctgtcataaa actgttcaaa
     1201 tgcccatgga ggttaaaata accatacata cgaatataaa aatagctgaa tattaaatgt
     1261 gctaatgaaa gaaaagcaat actaagtgta aaaaaaagat gtttcttctg catgattgtt
     1321 ccagtccctt actaagatag atagtcttta ttataccacg tgtgagggga gaaataaaaa
     1381 gccgtttttt agtagatatg aaacaaaaca aaaacccgca tttattcaac ctattcatcc
     1441 ttttaaagga tagattgaac gtagatagaa gtcgtttatc cagtcttttt cattttgaaa
     1501 aaaagctaac agcatgcttt ttttatggta tactagcaag gaaacgaatt cgcatcatgc
     1561 gataaaggag gaagagcccc gtggcagaaa aggaaacttt ttatatcact acgccaatct
     1621 attatccaag cggcaaactt catatcggca actcgtatac tacgattgca tgtgacgcaa
     1681 ttgctcgtta taaacggttg atgggctttg atgtgtttta tctcactgga gtggatgaac
     1741 atggtcaaaa aatcgaaaca aaagcagaag aactaggtgt aaaaccgcaa gaatatgtag
     1801 ataaaatggc ggctgatgtc aagaaattat ggaaaacgct tgatatcagt tatgataaat
     1861 tcattcgcac gacagatgat taccataaag cagctgttca aaaaatattt gatcgtttat
     1921 tagaacaggg agatatttac ttaggtgaat atgaaggctg gtactctgtt tctgacgaag
     1981 aattctttac agaaacacaa cttgcagaag tgtacaaaga tgacgaaggt aacgtgatcg
     2041 gtggtaaagc gccaagtgga cacgaagtag aattggtaaa agaagaatca tacttcttcc
     2101 gcatgagcaa atacgcagac cgtctattgg aatactatga agaacatccc gaattcatcc
     2161 agccagaatc tcgtaaaaac gaaatgatca acaactttat caaaccagga ttagaggatc
     2221 ttgcagtttc acgaacaact tttacttggg gagtaccagt caagagtgat ccgaaacatg
     2281 tggtgtatgt atggatcgat gcattatcca attatattac tgcactagga tatggctccg
     2341 aagatgaaag tctattcgaa aaatactggc ctgcagatgt tcagatggtc ggtaaagaaa
     2401 tcgttcgctt tcatacgatc tattggccaa tcatgctgat ggcccttgat ttgcctctac
     2461 ctaaaaaagt atttgggcat ggctggctat tgatgaaaga cggaaaaatg tctaaatcaa
     2521 aaggaaatgt cgtttatcct gaaatgcttg tggaacgtta tggtttagat gcactccgtt
     2581 attatttgct tcgtgctgtt ccgtttgggt cagatggtgt ctttacgcca gaagattttg
     2641 tttcccgtgt caattatgat ctggcaaatg atctagggaa cttattgaat cgaacgattg
     2701 ctatgatcaa caaatattgt gatggactcg ttcctgacta tgcctcactt gtcactccat
     2761 ttgatagtga actgtctacg acggctgcta acgttgtcgg acgttaccat gatgcaatgg
     2821 aaaaaatgga attcaataca gcattggctg aaatctgggt gctgatttct cgtgcaaaca
     2881 aatacattga tgaaacagaa ccatgggtat tagcaaaaga cgaagaaaag aaagctgaat
     2941 tgaatagtgt catgatccat ttagctgaat ctttgcgtat cgcagcgata ttacttcagc
     3001 caatcatgac agaaacgcca gagaagatct tcaatcaact aggattggac tctgaaacaa
     3061 tgaatcttga aggattacac tttggcgaat ttccttcagg aacaaaagta gttgcaaaag
     3121 gtacaccaat cttcccacgt ttagatatgg aagaagaagt tgcttttatt caagaaaaaa
     3181 tgtctgaagg tactcaaaca aacgaagata cagtcaaatg ggatccagaa gaaacagaac
     3241 ttgtttcaac gaaagaaaaa caaatcaaat ttgatgtatt tgaaaaagta gaactaaaag
     3301 tagcagaagt catcaactgt caaaaagtag aaggggcaga taagttgctg caattccgac
     3361 tagatgctgg agacagccaa gaccgtcaaa tcttgtcagg aatcgctgaa ttttatcctg
     3421 atccaagcga attgatcggg aaaaaagtcg tcattgtagc aaatctgaaa ccacgaaaga
     3481 tgcgtggaca aatcagtcaa ggaatgatcc tttctgcaga agcaccagat ggctctttac
     3541 aagtaatcga agcaccaaaa tccatgccaa atggctcaga aatcgcatag aaattcaaag
     3601 ggggtatgac actagttgtg tcataccccc tttttccgaa atttgagaag caattttcgt
     3661 aaattccttc ttattacttg aagccaatca tataatacag aaacagagaa ctatccaaaa
     3721 taaatcctag aaaaagaagt acgagcttcg ctgatttttg ttaatttaga ataatactaa
     3781 taggaatcgt aaaaacagaa aaaaagcata atgataaagg gtcgggcaga ttttaattga
     3841 ttcatctggt actctttttt attgtcctta cattcataaa gtttgaatgc aatgacttta
     3901 ttacatctat atttatatct aacagtagcg ttgatgtgtt aattataagt tctatcactt
     3961 tatgttcaat tagtttgtgc tcttatatgt gtgattgaaa atatagataa aaaaacaatc
     4021 atcggctttg acttcgatga ttgttttctt tattttgtaa aaatcctatc acttgatttt
     4081 atggtaacct tttatttttg tcttcaaacg gcttggtaag agagcagtaa gcagtgcaaa
     4141 tgggatcgaa aagacatacc agaaaatcgt acgtccgata ccataatgtt gatagagctt
     4201 tgtcaacatc acgtgtaaca agatcaaccc taaaagcaag gagccagcta taaaccaatg
     4261 attatcccaa tgcatgactt cactaagtgc catcactcca aaaggataga aataaaaata
     4321 gatcccgact aaggtcatcc gccagttctt tgtaaatgtt ccgatattca ataaaaagaa
     4381 aatcgctgaa agcaaaatac cgataggcgg aaaaagccca accaaaaagg aatacaacat
     4441 cccccacaag atcatcacag gacctttgat caatgcaacg attgcgatga acaaagtcag
     4501 caatattagt ttttgtgata acgttgcaac agtcattaat ccaaataaaa ttaatgtgaa
     4561 ccaatgccaa tgggactgct gttgttcttt acgggaaaaa tcgacccggt tggataaata
     4621 atctgctaat ttcggataag aacgcttaaa atccataaac tgttcctcct tcgtggaaaa
     4681 ggtaggttta gtatacgaaa aataaaaaag aaatacatcc gtcttaagag ggagtttttc
     4741 actgaaagtg gagaaaaaag aatggtaaat taaaatattc tcagttatac tgaaaattat
     4801 accaaatttc aaagaagaaa gaggatggga atgaaaggca aactaaaacg agaaatcaat
     4861 ctgtttggcg cattagctac cgttatggga accgtgatcg gtgcaggcgt cttcttcaaa
     4921 actgctgctg ttactgctag tactcagtct acaagtttga cattgctagc ttggcttttg
     4981 ggtggtttct taacgatctg tgctggattg acagtggctg aattagctac agcaatcccg
     5041 gaaactggtg gagctgtaaa atatattgaa gctgcgtatg gaaaattgcc cagcttttta
     5101 ttaggatggg cgcaaagctt gatttacttt cctgctaata ttgctgcatt atcgattatc
     5161 tttgcgacac aattgacgaa cttattacaa ttatctaccg attatctttt gttgattgca
     5221 gtgatcaccg ctgtttctgt gacagggttg aatttgttag ggacaaaagt cggtgcttct
     5281 gtacaatcag tgacgttgat tgttaaatta ataccaattg ctgtgattgt catatgggga
     5341 ttattgaccc caggacaagg aactgtccag ttatttccaa tcgaagctgg aaaagatgtt
     5401 acttttgtcg aaggattgag cagtgcgttg ttagcaacgt tgtttgctta tgacggctgg
     5461 ttaggtgtcg gtgcaatggc aggggaaatg aaacggccgg aaaaagattt gcctaaagca
     5521 attattcttg gtttgagttt tgtaacagtc gtttatctat tgatcaattt tgtttttttg
     5581 aaaactttgc cgattgatca tcttgccggt aatttgaatg cagcttctga agcatcagac
     5641 gtcatttttg gaggaatcgg tggaaagctg gtcactattg ggatcttgat ctcggtatac
     5701 ggtgcattga acggttatac actaactggg atccgcgtgc cttatgcgat ggctttagaa
     5761 gacgagctac ctttcagtaa acagctgaca aagctttcaa agaagtttac ggttccttat
     5821 gttcctgcgg ttttccagtt agcagtagct tgtattatga tgagccttgg ttctttcgac
     5881 tttttaacag acatgttgat ttttgtgatg tggctattca gtttactgat ttttatcggt
     5941 gtctttattt taagaaaaaa agcgccggaa ttgccacgtc catataaagt accactttat
     6001 ccaatcgttc cgattattgc gattctcggt gctattttca ttttaggtat gacgatgatg
     6061 acgcaaacga aattagcatt gatcggtata ggtgttacct tgataggtat cccagtctat
     6121 tatcaaaaaa agaaaaaacg ctcagaagag taaaatattt caacaacaga cagaaaaagt
     6181 acgaactagg tcctctagat cttcgtgctt tttctatttc aataaaacaa gttcttctat
     6241 tttgattttt gctacttctg caagtagtgc ttatgtgcta aagtaagaat gaaaaggaga
     6301 gataaacatg atatttgatt ctcataccca tttaaatgct gaacagttca atgaagatat
     6361 tccagaaacg attcagcgag cacaagaaat gggggtaacg aaaatggcgg tcgtgggctt
     6421 cgatacgcca acgattgaaa agtctttgca attaagccat gactatccaa atatatacag
     6481 tattatcggc tggcatccga cagaggctgg cagttatacg aaagaaatcg aaaataaatt
     6541 acaagaacaa ttgactttac caaaggttgt agcattaggg gaaattggct tggattatca
     6601 ttggatggaa gacccgaaag aagtccaaga taaagtattt cgcagacaga ttgctatcgc
     6661 aaaagaaatg aacctaccaa tcagtattca tactagagaa gcacttgaag acacgtatca
     6721 aatcctaaaa gaagaagatg ttcgagatat cggtggaatc atgcatagtt tcagtggtga
     6781 ttatgaatgg gcaaaacgat ttcttgactt agggatgcat atttcattta gcggtgtcgt
     6841 cactttcaaa aaagcattag acgtccaaga ggctgcagca aatgtaccaa tcgaacgatt
     6901 acttgtggaa acagatgccc cttatctggc accagttcct tttagaggaa agcgaaatga
     6961 accaggctat actcgttata cagtagaaaa gattgctgaa cttcggaatc ttccgacaga
     7021 agaagtggct gcccaaacat ggacaaatgc gcaccgatta tttggtctaa gcgaacatgg
     7081 ataagatgaa gatccaagag attatagtcg ttgaaggaaa agacgataca agaaggctgc
     7141 gggaagtagt tgatgcagat acgatagaaa caatagggtc tgcaatcaat gaagagatcc
     7201 tgatgcaaat tgaacatgcc caagagactc gtggagtgat cgtttttacc gatcctgatt
     7261 tttcaggaga aaaaataaga aaaatcatta tggaagctgt tcctcaggca aaacatgctt
     7321 ttttgccgcg cacacaagct aaaccaaaga aaaagggaag ccttggtgtc gagcatgcaa
     7381 gtgatgctgc tattttagaa gcattgaaaa aggtcgtgac gccagacatt tcccaaacgg
     7441 ctgtttctga aatcactaga caagaccttt tagactatgg tttaatagct ggggcacaag
     7501 caaaagaaaa acgagaaaaa ctaggtgacg agttgcgcat cggttacacg aacggcaaac
     7561 aattggaaaa acgtttgaag atgtttcgta ttacgccgaa agaactcgcc caagcaatga
     7621 aaatagtgga ggaacaacat gagtgaatat cgtgaaattg cgacaccctc tagaacaaaa
     7681 gagattttat tgaaacatgg tttttcattt aaaaaaagtt taggacaaaa ttttctgact
     7741 gaaccaaata ttttaaggaa aatcgtagaa actgcgcaaa tagatgaaca tacgaacgtg
     7801 atcgaagttg gaccaggaat cggtgcattg acggaacaat tagccaagca tgcaaaacaa
     7861 gtcgtagcat ttgagatcga tgatcgtttg atccctgtat tggctgatac gatgcaaccc
     7921 tatgacaatg tgactattgt acatcaagat attttaaaga ccgatttgtc aacagctgtt
     7981 agagaaacat ttcatgagga gcttccgtta aaagtcgtag cgaatttacc ttactatatt
     8041 acgacaccga tcatgatgca ttttcttgaa tcagatttgg ttgtggatga actagtcgtc
     8101 atgatgcaaa aagaagtagc tgatcgtatc tctgctgaac caggaacgaa agcttatggt
     8161 tcattatcga ttgctgttca atattatatg gaagccagtt tagcattcat cgtaccaaaa
     8221 acagtatttg tccctcagcc aaatgtagat tcagcgattt tgaaactgac aagaagagat
     8281 ataccggcag tcgaagtgac agacgaaaaa gcatttttcc gattgacaaa agcggcattt
     8341 cagcaaagaa gaaaaacgct ttggaataac ttgcagcatt cgtatggcaa agatgaccag
     8401 acaaaagcat ggttagcaaa aagcttggaa acagctggaa tcgatccaaa acgtcgtggg
     8461 gagactttgt cattacaaga attcgccgca ttaagcaatg cgatgtcaga aaatatgcag
     8521 taaaaaaaga ggttgtgaca gaagttgtga aaaagctgtc ctgcatcaag taataagaac
     8581 agccaaacaa aaatagttcc tcatgttttt cgtttgtttg ggcttattac cgcagatgca
     8641 agcttttgaa caccgtttaa gaaagaggtt gtgggcctgc cgtttaactc taagtcacaa
     8701 ggaacaattt caaaaaacag cttctcatgt ttttgagtta gttggtctta ttacttgatg
     8761 caagcttttg accactatta tgccgaacaa ggagatgtga cacaaatttt gtcacatctc
     8821 ctatttttgt ttcttgatca aaaaattctt atacttgata ctcacactca ttttgtatgg
     8881 atttagaaaa gaatatgtgt cttgacagtt attagtaagt gagttatact aagtcgacat
     8941 ttatgtgtca agacatatta ggagagagaa aaaatgagaa aaaattcagt tcgaaaacta
     9001 acgatttctg ctttattgat tgggatgggg gtcattatcc caatggtcat gcctaaaatc
     9061 atgattccac cagcttcctt tactttggcg tctcatgtgc cattatttat tgcgatgttt
     9121 tttacaccag gagttgcagt ggctgttgcg ctaggtacga catttggttt ctttttaaca
     9181 acgccggtta tcatcgcatt gcgagcattg tcacatcttg tgtttgcgtt gattggggct
     9241 tggtacttgc aaaagcatcc gagtatcgtt ttaaaaaatg gacagtttac ttttgctaat
     9301 tggcgtttcc aagggttcaa ttttgtgatc ggtgtgattc attctttagc agaaatgcta
     9361 gtagtcagca tcttttactt tattggtaat atgcctgaaa catattattc tcaaggatat
     9421 ttttatacag tattcatctt gatggggatt ggtgggctta tccacagttt agttgattat
     9481 aatattgctt attttatagc aggaacactc agcaaatatt ttgatatccc cgtatttacg
     9541 gcagcaaaaa aagaaaatcg gaaagagtcg attcaagggt acgcgaagaa aacgacatat
     9601 tagacatgat ctctcaaaaa aaaaactctc atctagtaat ggataataaa tcctctaaga
     9661 tgagagtttt ttgtcctaaa aagagctgca ccaacatctt ctggcacagc tctaacaggg
     9721 ggcaatttat ggaagtttga tgacttgttc tgtttcttta tcaaagaagt ggcctttgct
     9781 gatgttgaag gcaaggtcga ctatttcgcc tggtttatgg aaatctcttg catctacttt
     9841 tgagatgaac tcagtagaac cagtttttgt gtaaagcatc gtttcagctc caagtaattc
     9901 ggaaacgaca acttctgatt tcactacggc ttcaggtgaa gcttcaaggg ctacttgttc
     9961 actgtggatg tcttctggac gaataccgaa gataacttct tttccttcat aacctttttc
    10021 aactaatact ttgttttttc cttcaggaat acgaagctta agcccatgtc catctgtgat
    10081 aacaccattt ttcaatgtca cattaaagaa gttcatggca ggagatccaa taaagccggc
    10141 aacgaacata ttgacgggtg tatcataaac ttctttcggt gtaccgattt gttggataaa
    10201 tccgtctttc atgataacga ttcggtcagc catagtcatt gcttctgtct gatcgtgagt
    10261 aacatagatg gtcgttgttt caagacgctg gtgaagtttg gcaatctcag cacgcatggc
    10321 tacacgtaat ttagcatcta aatttgataa tggctcatcc attaagaaga cttttgcatc
    10381 ccgaacgatt gcccgtccca atgccacacg ttggcgttgt ccaccagata aagcagctgg
    10441 ttttcgtttc aagtattctg tcagacctaa gatctctgct gcattgtcca cacgtttttt
    10501 gatgtctgct ttatcatatt tacgtaattt caagccaaaa gccatattat caaaaacagt
    10561 catatgagga tacaatgcgt agttttggaa aaccatggca atatcacggt ctttaggtgc
    10621 cacgtcattc atgacttttc cgccgatatt tagttctcct tcagagatat cttccagtcc
    10681 cgcgatcatt cgcaaagtag ttgactttcc acaaccggaa ggaccaacaa aaacgataaa
    10741 ttcacggtct ttgattgata gattaaaatc agttacagaa taattttctg cattgtcata
    10801 ttttttatat acgtttttca gagccatttc taccataata cgttccacac tttctttttt
    10861 agttttatta actatttaaa gtataaatga aagcgttaac taacttcaat gtcatgttga
    10921 acaagaattt tttctttttt ttgtcaatgt gctagtttta agctttaata aatatccata
    10981 agaaataaaa actgatacac tggagtaaat aagtatgtta acaatatcaa aaggagtgtc
    11041 tcttatgaaa atcgctttga tcgctcatga ccgaaaaaaa cctatgatgg tgaaattagc
    11101 aacagcgtat aaaacaatat tggaaaaaca tgaacttttt gctaccggga cgactgggca
    11161 gaggatcacg gaagcaaccg gcttgccgat ccatcggttt aaatccggac cgttaggcgg
    11221 ggatcagcaa attggagcca tgatttcgga ggatcagtta gatttggtga tttttcttcg
    11281 agacccgctg gctgcacagc cccatgaacc agatgtaaca gcacttatcc gtttatctga
    11341 tgtctatgag attccgttag ctacgaatat cggaacagct gaggtgctac taagaggact
    11401 ggaagccggc ttcctagatt ttcgaagaat cgtccatgaa atagacaagc atccactttc
    11461 attttgatgg ataagcgtat ggaaaaataa cgtttaatgt tcgcctatat gtagctataa
    11521 aagctaaaca aactgataat atgcgatata atacgaacgt attggataat ataaacaata
    11581 atattagttt ttcgtatttg cagtaaatgt gaaaatatgc tatagtttct gtgggaaaag
    11641 atcccaaaaa taatacagag tagaaaataa agcgttaagt gctaagagga tgggatgttg
    11701 cctcttggac gaaggacgta atgttcgcgg ttttattttc gcattcgctg catgatacga
    11761 tgtagcagct cttaaaggag atgctaaaaa tgaagaaaca ccggttagac gcacgtatga
    11821 ttgctattat gggcttattg attgcattga tggtcacttt gtcccgactg gtagcaatcg
    11881 agaccccatt tattaaaatc agtgtcacat ttattccaca agtgatcatg ggcattcttt
    11941 ttggtccttt ttggtcaggg ataggcgcag ttttagctga tttagtagga atggccctct
    12001 tctcgaaatc tgcattcttt attggattta cattgaatgc atttattgaa ggagcaatct
    12061 acggattctt tttctatcga aaagagatca cttggaaaaa tgccattctg gctacgctta
    12121 gtgtcacgct gatcatcaac ttatttttga caccattatg gcttgcgttg atgtaccatg
    12181 tgccattgtt cagctgggtc gtttgggcgc cccgcctgtt aaaaacagta atatggttac
    12241 cgattcaatc aattgccatt tattacgtag gacgtagtat tccttacaaa aaaattttaa
    12301 gaagtttagc gatccacgct aaataaaaaa caagcagtct tcccatccca gaagactgct
    12361 tgtttttatt gtgctgtgaa ttgtgcttga tagagccgtc ggtaataacc atctttttga
    12421 agcagctcat catgggtgcc catttcgaca atagctccct gatccatcac taatatctgg
    12481 tccgcatttt tgattgtgga caggcgatgg gcaatcacaa aactggtttt tccttccatc
    12541 attgctaaga aggcttgttg gatttttttc tctgtcaatg tatcgactga gctggtagct
    12601 tcatctaaga tcaacatagg gggattactg atcatcgttc gagcaatcgt caacagttgg
    12661 cgttgtccat ctgatatctt taacccttga ccgccaatct tagtatctaa tttttccggc
    12721 aaacgttcta caaattcata catataagag gcttttaggg catcattgat ttctgcgtca
    12781 cttgcttccg gattcccaaa acgaagattt tctcgcaatg tactgtcaaa tagccaagta
    12841 tcttgtaaca ccattccaaa acttttacgt aatgtatcac gttggataga gcggatgtca
    12901 tggtcatcga ctgtaattgt tccttttgtt gtgtcataaa aacgcatcag caaattaaca
    12961 agtgtggatt ttccggcccc tgtttttcct actatagcaa tggtttgacc tggataagca
    13021 gtaaaattga aatcttcgat caaacgctgc ttggggtcat aagaaaaaga aacatgatca
    13081 aaagagactt ttcctttgat atttttgggt tccaaggcat aggcatctgg caaatcaggc
    13141 ttttcttctg gctgatcgat caaatcaaat gctcgttcta gaccagaaaa agcggtttgc
    13201 agttgtgtcg tgattccaga aagttcgata aatggtttag aaaactgact tgagtagatc
    13261 gtaaagctgg aaatcacacc aacagtgatt gacgaaccac tcttcaatgc caataggccg
    13321 ccaactaaac caatcgataa ataagcaagg tgatctacaa aacgagaaga cgggtttgtc
    13381 aaggaagaag aaaattgtgc ccgttgtcct ttttcatata gatcagcatt tagcagttca
    13441 aattgctgtt gactagcttc ttcttgctga aaagctttca cgattttctg gttaccgatt
    13501 cgttcggtca caaagcccga gatatcccca ataatccttt gctgtctatc gaaatttgtt
    13561 tgtgaagcac gagcaacgat ccaactcaca aggaaaataa ttggtgtaga acaaagaacg
    13621 accaatgtca gaagtggact tagacgcatc ataaaaataa acgaaagaat gatgattgcc
    13681 actccagaaa ataattgatt gaaggccgca gaaattgcaa tggaaatatt gtccatatca
    13741 tttgtaaatc gactgacgat atttccgtgg gagttttgat cataataacg aagtggcaat
    13801 cgattcagat gagcaaatgc atcttttctt aattttgcaa cggataagta agctaaccga
    13861 ttgcttaaca cttggatgag ccattgactg actacgttga ttaaaacgat accaccgaat
    13921 agaataagta aatggaacag tcgattgaag cggacctgtc cttctccaat catttgatcg
    13981 atactttgac caatttgtaa cgtcatcaca actgttgcaa tcccattgat gattcctagt
    14041 atcacagcta gccaaatgtc ttttgcatag gcagtaaggt aaggaatgaa tcggcggagc
    14101 gtctgcaagg ataatttttt tactttcata actattcttc ctcctgtgat gcgacgattt
    14161 cctgatattc tgctgattga gcaagtaatt cttcatgggt accctgagca gcaatcttac
    14221 cttgatccat cactaagata tgatgtgctt cttgaataga gcggacacgt tgggagataa
    14281 taatcactgt actgccaaga taagtctgta gcgccttacg caaatccaag tctgtttgat
    14341 aatccaacgc acttaaagag tcatctaaaa tcagtaatgc tggcttggca atcaaagctc
    14401 ttgcaatcgt cagtcgctgt ttttgtccgc cagagaaatt tttcccattt tccatgactt
    14461 ttgtatctaa accatttgga agctgacgga caaattcttc tgcctgagcg attttcagag
    14521 cttcccaaca ttctttttct gtggcgtctt tcttacccca ttgaaggttt tcacgaatag
    14581 tcccggtaaa tagtacagaa gtttggggaa caagagcaat ttgctgacgg agatgatcca
    14641 gctgccaaga acgaacatcc attccgtcca ttataactgt accggaactg acatcataga
    14701 aacgcggaat caattgtgtc aaagtcgttt tcccgcttcc ggttggacca atgattccaa
    14761 ggactgtatt tcgcttcagc tgaaatgtaa tattttggag agaaagacca gaatcaggag
    14821 tataacggaa gtcaacatgg tcaaaagcga taattgcttc agaagaaaaa tcgggagtag
    14881 tactgacctc agcttcaaga atcgaatttt ctgtgtctag cacctctttc acccgatttc
    14941 ctgaagcttc ggcacgtgtg aagatcacga cgaggtttga aacaacgatc agtgccaaaa
    15001 gcatttgatt catataattg atcaaagcaa gaacttgtcc ttgttgcaag ctaccaatat
    15061 ttactttgat cccgccaact gtcagcaaac agatgatccc gacattcatg atcaaggttg
    15121 tagcaggtga taatagggca gagatattgg aaacacgtaa ataattgttc gctagatcat
    15181 ttgtgctttt atcgaacttc tctgtttctt tttttgtctg cgcaaatgcg cggatgacac
    15241 gaacaccgct aagattctga ctaacgtgtt cattgagctg atctagtttt tcttgcactt
    15301 tttggtagag aggaacggtt tttttgatga taaaaaataa aatgattgag aaaataggca
    15361 ataatgctaa gaaaaacaga cctacttccc agtcgatcac aaaagccatg accactgacc
    15421 cgatacttaa aaacggtgct ctgatcaata aacgaatgac cattgctaaa gctagctgaa
    15481 gctgattgat gtcgtttgtc attcgggtga tcaaggtatc tgttccaaaa tgattcaact
    15541 cgttgtgaga gaaagtattg atttttttga ttagctgatt acgtaactct gtaccaaatc
    15601 cttgtgaagc tactgaagca tagtattggc aaatgatagc acaaatcaga ccaatcacag
    15661 acatagcgac catccataag cccatttcaa tgatttttcc tcggtcattc atttttagtc
    15721 cattatcgat caaggaagcc atcattaaag gcaggacaag ttcgaagaca gcttcaagaa
    15781 atttgaagaa cgggcccaaa atgatttgct tacgatagtc ttttgcataa cgtaataact
    15841 gaatcatatg attcctccta ttatttattt gtccacaatt gaaaaaacaa gtactaccac
    15901 attgtagctt aggaaattta gaatgaaaag agaacaagcc ttttcataaa tgaaagtttt
    15961 attatgaaga agctttagaa attgaataga ctattttttt taaaaaaaag aaaatgagaa
    16021 aacatgccag tctcttcatt cataggaacg tctattttac ttaatttttc tataaatgaa
    16081 ttctgcataa aaaatatatc aagtaaatgt ttatagatga aactctattt acttcttttt
    16141 taatttgttc ttgcaatctt ttttgctacg taatttttgt aaaaaagtgg gttgagagaa
    16201 atctaattga ttttcaaaga aggagtatga aaatgagaaa aatatttatt cgtttattgt
    16261 gggtactatc ttagaggaat aaataatagt ggagaaaact atggtttggc gcagattcta
    16321 tcaggtttga tggaacgaag acaacctccc gacatcaagt caaaagctac ttgagatttt
    16381 gatctgaaaa taaaaaaaga aaacaaggta ggaacatcaa tgtttctacc ttgttttcgt
    16441 aatcaatggg aaaaaactaa gagtggtgta cgtaatcaat aaaaaggatg gtgacaacag
    16501 tacctcttta ctctctgaaa gcatcataac tcgtttttcc tcattatgcc aataaattgt
    16561 tgttatacca catataagga tttgtaatag ctaaaaacag acaggaaagt tgaaatctgt
    16621 gaatcttatt ttgtatggaa ggatttatag aacgcaaaaa tcaagataaa gatgaataaa
    16681 aatcctgttt cggctatata ttgcgtatct acgccaataa aacgagtttg ttctgtcata
    16741 gccatataaa gcaaaggcaa aaatacaact acagcgagat aagatccgat gatttctcga
    16801 aaagttttcc aggaagtatg tttcctgttt ttatatttat ccgatttcat tgaatagtca
    16861 tagcctcctt attctttcat atgttgaaat tccagtataa aaactggaag gaactgtacg
    16921 ttttttagaa taaaaattat aagggataag taggctgctg tctataataa gatatatttt
    16981 tcaattcttt attaaagatt ttattgacaa aatgaatccg ttttctatga tggaggaggg
    17041 gtgaataagt tgttgaagaa ggaaatttta tgttacttag agaaccagac agcctttttc
    17101 gatttagaac atatgaacga ggtctttaca gcacaaaggt tagctgatca ttttggggta
    17161 aaaagaaaca cagtcagtca ttatttgaac cagttaaatg atgagcaact actagtcaaa
    17221 atcaattctc gaccagtgat ttatttccac aaagaagctt ttgaaaaaca attttttaag
    17281 ttacgcacga atttttattt ttctatcgat gatctcaaag aggaacagcc ttttttcgcg
    17341 caaccaaaag acttattctc ttttatgatc ggatacgacg ccagtttgaa agaaagtatc
    17401 gaacaaatca aaacagctct ttactatcca gatggcggat taccactttt gattacaggc
    17461 gaaagtggca caggtaaaag ttatttagtt aatttggtct atcagtattg tctgcttcat
    17521 gatctgctag aagattctgc accattcatc acttttaatt gtgcacaata tgcagataat
    17581 cctgaacttt tgactagcaa tttgtttgga catgttaagg gagcgtacac tggtgcagaa
    17641 gaaaataaaa aaggggcttt tgaagcagca gatggtggga tcttgttttt agacgaggta
    17701 catcgcttaa caccagaagg tcaggaaaaa ctgttcacct atcttgatca aggtgtgatt
    17761 tatcgtatgg gagaacctaa tttgtcacgc cggatcaaaa cacgtctctt ttttgctacg
    17821 actgaagaga ttactagtca tttcttaaca actttcattc gaagaatacc tatccgaatc
    17881 gaactacctg cacttaatca gcgtagtcgt aatgaacggc tagaactgat ttactctttt
    17941 tttctcgaag aacaaagaaa aatggggagc cctttgtcag tcagtggacc agctttgtca
    18001 cttttaacaa gtcagaaatt atccggaaac ataggagagc tgaaaaatat cgtcaaagtt
    18061 tcagcagcaa aagcatatgc tgaacagcgt gaacagcctg aaatccatgt cacgatccat
    18121 catttgcaaa aagaactact tgcgcagcct attactaaaa atacagcaca gcaaggaatc
    18181 tatattacgc aagaccagac cttagagcaa ttaatggaga agcaacagcc cgaacagcag
    18241 cgaatcgtta aaagttttga gcaaatccta attgatttca agaaaaataa ctgtctgcta
    18301 tattcttgcg aaggaaaatt aaagcaagaa gtgattcaat tatttgattt tttgctgttt
    18361 gagaccagta gacaagaaaa acacgagctg ctggtttatt ggacacaatc tatccgagag
    18421 acctttcgac aaatggaaac tgcctatcaa atcaaattcg atggaaacag tgtctatgcc
    18481 ttgagttact atctctatca gcgaagcact atcaaatggt taccggaaga acatgatatt
    18541 atccaactaa tcaaagaatt agaacaacaa gtttctcagt cttatccatc tagttatcac
    18601 tatgtccaac gaattctgga attaagtaag atcaaattag atattgaaga cacaagtatg
    18661 gatcggattt tactgacgat ctatctaaaa aaagcgaaat ggtcaaaaga aaaacgactg
    18721 ccaaaagcga tgattgctgc tcacggttat gcaactgcta gcagtatggc aaatgtagta
    18781 aatcgtttat tacaagagga tctatttgaa tcatttgata tgccactaga tgtcacacca
    18841 cagcagattg cttcagaaat ccttgattat tgcgaaaaca gcgatgtttc aaatggattg
    18901 atcatattag tagacatggg atctctgaaa gaaatccatc agttttttaa aaaacagtta
    18961 tccgtaccgc ttttgatttt gaataatgtg acgacacctt tagcaatcac agtaggggaa
    19021 tgcctgcaaa aaaatgtatc attagaagag atagcagaag agactgttcg acagatccag
    19081 ccagaatggc gactgctcta tccagaggaa aacaaaccca aagcactcat tactacttgc
    19141 ttcactggaa tcggtacggc ggtccactta agtgaactgc tagaaaaaag cttacctacg
    19201 gcttgtcagt tgaaaatcat cccatatgaa tatcagcaat taaaagataa gaaaaacagt
    19261 gacccattat tttccatata cgaagtcgta ggaatgattg gcaccacaga tcctgatatc
    19321 accaatatcg actatctttc attagaagac ctcatctcgg gggaaaagat gtctgtacta
    19381 gctgaatggt tggacactac tatgaatgct tcagagaagg aaatattcaa tcagcgcatc
    19441 attcgtaatt tttcattgga aaaagtactg gattccgtga ctattctaga tacagagaag
    19501 gtgatgggag aaatcgatca ttttatgaga gaattagagg tgcagttgaa tcgaagcatc
    19561 agcaatccca aaaaattagc gttgtatgtc catgtgagct gtctcattga acgattgatc
    19621 cgacaaatgc caatcgaaac ctatcaagga ttagagaaat ggaagcagtg tcaaaaagaa
    19681 gggttatctg ctattaaatc tgcgtttagt gtcattgaag agcattatag tgtcatgatc
    19741 cccaattctg agattgccta tatctatgat attttgagtg aagatacaga gtttctctcg
    19801 atagaagaag aattttgaac ataagcaagt tgttgccact aattttggca tgcaacttgc
    19861 ttttttagta tgtgtaagtg aaaagaggag atgaaaaagt ggatagagaa attatcttag
    19921 cttcccatgg aaaatttgct tcagggatat tagattcatt agagctgatc tatgggaaaa
    19981 atcattctat tactgtattc gattgctata ctgatgagaa ttttgattta gcggaaacag
    20041 taaggcagct ttttatgagg tacaaagata aagaaatcat tgttctgacg gatctttttg
    20101 gcggaagtgt caacaacgaa ttcttacaat atatcaatcg ggatcatgtc tatctcgttg
    20161 ccggattgaa tttgccacta ttgattgagc tagtatctcg gttggacgct gaagtagaga
    20221 caactgtttt gatccagcag gtgctaactg attcaaaaaa aatgatccag ttttgtaacg
    20281 agcggctcaa tcagaaaata gaagaagacg aattttagga ggaagaaaaa tgattgtatt
    20341 gacaagagtc gaccatcggt tattacacgg acaagtagct ttttcatgga cacaaacaat
    20401 aggcgcagac tgtattttga ttgctaatga tgatgtacct acgaatgaga tacgaaagac
    20461 aacgatcaaa ttagccaagc cacaaggagt caaactagtg atcaaatcaa ttgatgactc
    20521 gattgccgcg ttgaaaagcg gggtgacaga taaatataag ttattcatcg tagtggaatc
    20581 gatcgaggat gcatataagc tggcagaagc gtatccagaa atcaaaacca tcaacttagg
    20641 agggatcaag gcaaaacctg gtactcgcag catcggaaaa gcggtaaata ttttaccaga
    20701 agaggaggaa cgcttgaaac gattaattga caaacaaata gaagtagaaa tccgtcaagt
    20761 accagcagat aaaaaagtgg atgtaagaga agttttgtaa gaaaggaaga acctcaatga
    20821 ttgtacaagc agtcttatta ggaattgttg catttgtcgc acaatcagaa tatgcactag
    20881 ggacatcgtt gctttctcgt ccgattgtga cggggctgtt tacaggaatc gtgttaggtg
    20941 atgtaaaaac tgggatcatt atgggcgcaa ctttagagtt agcatttatc ggatcgttct
    21001 cagtaggtgc ttcgattcca cctgatgttg tgaccggtgg gattttaggg acggcttttg
    21061 ctattacagc tggagccggt acagaaaccg cgcttttact aggtttgccg attgctacgt
    21121 tgacattgat attgaaaaat atttacttag ggcttttgat tccaattatg aaccataaag
    21181 cagacaatta tgcagaagaa ggaaattata aaggagtcga gcatatgcac ttgcttgccg
    21241 gtatcggtct ttccttgatg cttggtgttg tggtaatggt ttcttatatg gtgggaagca
    21301 atacgatcgg aaatctatta aatatgattc ctgacttcgt tcaaaagggg ttgtcagtag
    21361 ctacagggtt gattccagct cttggttttg cgatgcttgc tcgtttgctg atcaacaaac
    21421 aagttgcacc atattttttc ttaggttttg ctatagcttc ttacttagag attcctgtga
    21481 ccggagtagc tatttttggt gcgattttag cagttgtggt agtcaatatt atgaatgtcc
    21541 gtcaactacc acttcaaaca actgcagggg aggtagaaga agatgaagaa ttctgagatc
    21601 aaaaacagca aaataacgaa aaaagagcta aatcacgtat tttggcgttc ttttcaaatg
    21661 gagttttctt ggaattatga acgtcagatg aatatggctt atgtttatgc aatgattccg
    21721 attttgaaaa agttatatca gtcgaaagaa gaaatggcag cagctttgaa acggcatcta
    21781 gagtttttta acacgacccc acatatcgtt acactgattt taggaatcac ggctgcaatg
    21841 gaggaagaaa ataaggatga tcctgaattt gatgtgactg cgatcgatag tatcaaaaca
    21901 tctttgatgg gacctcttgc agggttagga gattctttct tttggggaac tttgcgattg
    21961 attgccacag gtgtgggtac ctctttagcc atgcaaggaa atattttagg ccctatcttg
    22021 ttcattttga ttttcaatat tccgcacatt ctgtttcgct atctagcaac aggttgggga
    22081 tatcgcttag gaacgggttt tttgaaaaag atccaggcaa acggtatgat ggaaagtttg
    22141 acattaggcg cgtctattat tggactgatg gtcgttggag caatgactgc cacgatgatc
    22201 accatcaata ttcctttaaa aatcggttca ggagaaaatg ctgtgactgt tcaaagtatt
    22261 tttgatgata tcgttccaaa tatcttatgt cttggagcat ttggcatagt gttttatcta
    22321 ttgaagaaag aagtgaaacc attaacgatc ttgatcggac tagctttctt tggaattttt
    22381 ggttcgtgga tagggatttt ttaaaaaagg agcagagaaa atgtttacga tgcaagatta
    22441 tatctatgaa gaaaaggaag tactaagtac gatcttgaaa aagaatgatt tttcgacaag
    22501 agaacatatg aaaaaaacag tgaatttact gatcttagca acgggttcat cttataacgc
    22561 ttgtttagca gcgaagccag cattggaatc ttatggtgat cttactgtcg atattcaaga
    22621 acctttttat tttttcaatt atggaaaact ttctccttca atcgatactg tgattgctgt
    22681 gtcacaaagc gggaaaagtg cttctactgt tgaagcagta aaaatgatac aaaaacaagg
    22741 gttacctgtt gttgctatca caaatgacgt gcaaagtcca cttgctttag aagctgcaca
    22801 aattattgat ttaggtgccg gggtagaatc agtaggcttc gttacaaaag gctattctgc
    22861 gactgtttta cagttactac tcttagggat aggaattgga ataagtaaaa ataaaatcag
    22921 caaaaaaata gaacaagact acatgcaaca gttgcgcaaa ataatcaacc atttaccagc
    22981 gattattcaa aaaacggaag aattttttga tggatatcaa agtttatttc gtttagcaca
    23041 gcgtttcgtc accattggat atggtccaaa ctggggaaca gctaaagaag cagagacgaa
    23101 attgactgaa acaatccgcg ttccgtcaca aggatttgag ttagaagctt atatgcacgg
    23161 cccatacctg gaggcagatg cttcgcattt gctattcttt attgaagggg aaagtgtaaa
    23221 taaggaacgt tcgcaaaagt tgcaaagata tatgagtcgg tacgttggag agactctcac
    23281 cattaccaca aaaaaagcaa gaaacgagaa aacacttgga ttagcaatag aatgtgatga
    23341 atatctgtct gtattagcgc ttgtcgttcc gtttcaacta ttcgcttata aaaccgcagt
    23401 agctaaaggt attgacttga acaaaaagat ttttgaagac tttgatacag tcttgaaaag
    23461 taaattataa gaggtggaaa tcatgctgaa attcaatgaa gaagaacaaa tcaaagcaat
    23521 aaaaggcgca ctagctttac gtccgcaagt agaagaaatc atcgataaac tttatgcgga
    23581 aaaatttgac gctgtctatt atctaggaat cggtggaacg tatgcttcct cgatgcaagc
    23641 tgtcacttat atgaatggga aaagcaactt gcctgtcttt gtacagcatg ctgcagaata
    23701 ttacactact ggaaacaaaa gattaacaaa agattctatc gttattttgt cctctgttac
    23761 cggtacaact caagaagtag tgaaagcagt agaacaaatc aagaaagtag gagcgacact
    23821 gattggattt atcgataaag cgaacagtaa gttgtctcag ctatgcgatt ttgtggtcac
    23881 ttatccagct cctggaacag aacaaatcaa attttttatg gcagcagatc gattgatgta
    23941 tttgaatgga gaattcgaag cttattcaga atactatgaa cagctcgaac gttatttacc
    24001 aacagggtta gtggaagcag agaaaaaagc agatgcattt ggcttatcat ttgcagaaaa
    24061 acatcgacgt gatagtatgc attattttat tggagcaggg aatcaatggg gagctgttta
    24121 ttcatatgcc atgtgttact gggaagaaca aagctggctt ccatcgaaat ctatccatgc
    24181 tgccgagttt cttcacggga cgttagagat cgtagaagaa acaaccccag tcacattatt
    24241 tttaggcgaa gatgaacaga gagtgttatc tgaacgtgtg gctaaacttt tgccaaaaat
    24301 ttgcagcaat tatacattga tagacacaaa agactatcca gtagaaggta tcagtgaaaa
    24361 atatcgcgga cgtgttttgt ctttcttatt gatgcatgta gtgacacaac gcatcgatgc
    24421 tcatgtggag cagttgaact gccatccatt agagatacgc cgctactatc gtcagtttga
    24481 ttattaggat agactggata aaaagaatat aaaaaataaa gagagcagcg ataactgctc
    24541 cctttatttt tttaaaatat tggcatcaat tacgttataa aacacatttt ttgcattatc
    24601 tacagttcaa cttataatct gtttaatggg acatgtgggt gccaaccatt ttttgttatg
    24661 caatagtact atttagttgt tgcatggatc cgtagtaaaa gtccaagtac aacgagttgc
    24721 gccagtttac atagcgtttt gtatccagaa tgttgactaa aacaaaagtt cctatgtcaa
    24781 ccgtcaacag agacaatctg tccgttgcag gacctgacag atttagaaat gttcaatctg
    24841 tctcttatgt attttaaatc aatactcact aggagaagtt tcctaacctc ctaatagtaa
    24901 tgctggtagt aacattgtca aaactgcttc ctcttaggaa caagcaaagc ataacgagtg
    24961 taaaaataaa atgtagacta ttgtaacata tcattgatta tttcaagtaa aaacgataaa
    25021 agaagtaaac aaacacttaa aaacaatgga aattagtccc aactttaaga aatgtatact
    25081 ataatggaaa ttatcaatta tttatttgga ggaatatcca tgaaacaaaa aatcgcagtt
    25141 cttggtcctg gatcttgggg cactgcttta gcacaaacat tggcagaaaa cgggcatgat
    25201 gtccgtattt ggggaaatgt acctgaacag attgatgaaa tcaataagta tcatacaaat
    25261 cagcattttt tacctgattt gacgatccca gaatcgatta tcggatataa agaattggca
    25321 gaagcagtgg ataacgcaga tgctatttta tttgttgttc caacaaaagc gattcgttca
    25381 gtcgcacagg aacttattgg taaaatgaat actaagccaa tcattataca tgcaagtaaa
    25441 ggactagaac aagatacgca taaacgaatc tcagaagttt tggctgaaga aattccagaa
    25501 gaaaaaagac aggcaattgt tgtattatct ggtcctagcc atgctgagga agtggcagta
    25561 catgatatca caacaattac agctgcaagt attgatcaaa aagcagcagc ctatgtacaa
    25621 aaactgttca tgaatgatta tttcaggatt tatacaaata atgatgtgat tggcgtagaa
    25681 actggtgcag cactgaaaaa tatcattgca attggtgccg gcgctatcca tggattagga
    25741 ttcggagatg atgcaaaagc agcaatcatg actcgaggat tggcagaaat cagccgtctt
    25801 ggtgtcgcga tgggtgccaa tcctctgaca tttatcggtt tgagtggtgt gggggacttg
    25861 atcgttactt gtacaagtgt tcattctcgc aattggcgtg ccggtaactt gttaggacag
    25921 ggacataagc tggaagaagt tctagaaaac atgggaatgg tcgttgaggg tgtggcaacg
    25981 acaaaagcag cagtagagct agctcaacag ctaggtgttg agatgccaat tactcaaaca
    26041 atctataatg ttttgtataa tggagaagat atcaaaaaag cagcaaaaga aatcatgtta
    26101 cgtgacggaa aaatggagaa tgaattttct cttcgttaaa tagatgatca atagttaatc
    26161 gtcgtttagg aggaacagca agtgaaggtc aaaaaagcag tcattcctgc cgctgggcta
    26221 ggaacacgtt ttttgccggc aacaaaagcc atggcaaaag aaatgcttcc aatcgtggat
    26281 aaaccaacga tccagtttat tgtggaagaa gcattggatt cgggaatcga agacatcttg
    26341 atcgtaacgg gaaaagaaaa aagacccatt gaagatcact ttgatgcaaa tatcgaattg
    26401 gaaaacaatt tgcgggaaaa ggaaaaaaca gaattactcg ctttagttga agaaacgact
    26461 caagtcaatc ttcacttcat ccgtcaatct catccaagag gactggggga tgccgtgctt
    26521 caagcaaaag catttatagg aaatgaaccg tttgtcgtca tgctggggga tgatttgatg
    26581 aaagatgata tcccattgac tcaacaattg atgatggatt atgaagaaac acaagcttcc
    26641 gctgttgccg tcatgcgtgt accagaaaat gaaacatcta aatacggaat tattgatcct
    26701 aaaacagata gcgaaaaggg tcgttgcaga gtaaaagggt ttgtagaaaa acctgaaatg
    26761 ggaaaagcac caagtaattt agccattatc ggacgttatc tactgactcc taaaatattt
    26821 gagatattag aaactcaaga accaggagca ggaaacgaga tacagctaac ggatgcactt
    26881 cagactctta accagacaga ggcggtctat gcgagagagt ttaaaggaaa aagatacgac
    26941 gtaggcgata agttaggata tatgaagaca aatattgaat atggacttca acattcggaa
    27001 attgggactt cattaagtgc atatattatc cagttgagta aaaagctaag aacagaaagt
    27061 taactggaaa taagtggcct gctgagaatg aaaggctatt tgttattaaa gcggcagctt
    27121 gtgcgtcatt tgcgcaactg tcgttttagt tttttgactc tagatcagtt gagtcgtgga
    27181 aaacgaaaga tagaaaaaga ctttcgtgaa tagattcaga aaatattatg ctaatggttt
    27241 aatttttttt taagttgtat aaaagaaaat gattacataa gagaaatgaa agccaagcca
    27301 gaagattcat agtagaataa aaaggcgaat tttttaatta taaaaaaagg tgtgtgttca
    27361 ctatgggaaa attagtcgct gttgcacagt cgctgcttga tatactcaag tggctgatgg
    27421 aaggaagcaa ttggatattt gtgttgccac tattgcttat tagtctattt atcatgtttc
    27481 gcatggtcag aaaaaaagaa acgtttctga tttttatctg gtatgcagca tccgttgggg
    27541 ttgctacctt gatggttgaa ttggcgttag gtagttggga agcttgcgta tttgctttat
    27601 tttttgctgt actgtatcta atcatttata tcccatatat gaaaagaaag tctcggatag
    27661 gcagaaaagg tagacataca actacttttt ctagtacaga ttctctcgaa caaagtagaa
    27721 gaacgagaag aagacggtaa tatttagtag gtatacgcaa aaaaagataa aataatggat
    27781 aaactattga gatgagagat ttatttaatt ggtggaaaaa agcttttttc acttatataa
    27841 aagaatcttt tttaaaggaa tgcttgttgt atcgggataa gccattcctt tttttatgtt
    27901 atttatatat atataaatca taccaatgt
//
LOCUS       DAFEKH010000037        27609 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.038, whole genome shotgun sequence.
ACCESSION   DAFEKH010000037
VERSION     DAFEKH010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27609
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.038"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..363)
                     /locus_tag="LP386_001803"
     CDS             complement(<1..363)
                     /locus_tag="LP386_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919038.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYAVCIIKRDK"
     gene            complement(538..2673)
                     /locus_tag="LP386_001804"
     CDS             complement(538..2673)
                     /locus_tag="LP386_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL1919039.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(2756..4411)
                     /locus_tag="LP386_001805"
     CDS             complement(2756..4411)
                     /locus_tag="LP386_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL1919040.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(4413..4727)
                     /locus_tag="LP386_001806"
     CDS             complement(4413..4727)
                     /locus_tag="LP386_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBL1919041.1"
                     /translation="MNLLFQSIKSITVPELKEKILENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            4897..5157
                     /locus_tag="LP386_001807"
     CDS             4897..5157
                     /locus_tag="LP386_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HBL1919042.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            5171..5485
                     /locus_tag="LP386_001808"
     CDS             5171..5485
                     /locus_tag="LP386_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HBL1919043.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(5970..6524)
                     /locus_tag="LP386_001809"
     CDS             complement(5970..6524)
                     /locus_tag="LP386_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HBL1919044.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(6650..8578)
                     /locus_tag="LP386_001810"
     CDS             complement(6650..8578)
                     /locus_tag="LP386_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBL1919045.1"
                     /translation="MDNEMISQLQFDRIKKEIQARAIGNYSKKRISDMTVSTNLQTVL
                     DRQEETREARLILESSQHVPFMGLPRIDALTEQVKKGLILQPTDLIEYADFLRSSRMI
                     TKFFDKNQYQTPLLFAYSKHLPDLINVEELIDQKIKNNKVSDDASRNLRKVRKQLQLI
                     EKEIQSKLLKFLRHPKNKEMIQEAMIVQKGEYYTIPIKASYKNKIDGTIIDESNKRTT
                     VFIEPTVISKLNEHYQLLKAEEISEEYQVLAALTGAIAENEEVIDLLIETITVLDIIF
                     ARAKFSREINGSTPRINKSEHIIIKQGRHPFLPEHAVPLDVEIGKDYRGLIITGANAG
                     GKTVVLKTVGLLTLMAMFGMQVPAKEGTELAVFDEIFVDVGDHQNLENALSTFSGHMQ
                     NIAAILKKIKRNTLVLLDEIGSGTEPNEGAALAIAIMESMYEQGALIIATTHYGEIKK
                     FAGDHEDFVPAAMAFDREALRPKYQLRVGETGESQALWIAHKMDMSMKLIHQAERYLA
                     EKAYRTQKKEFLPKTAVTNRKENKKERQLFAKGDRIFVNEYQKEALVYEDIGEDTIDV
                     YLDKKIIHVPRQRVRLVRSAEDLYPTGYDLDSLFIDYKTRKRQRDLERGSKKAHKVLV
                     KEMRKRQEERRVNDENSK"
     gene            complement(8884..9600)
                     /locus_tag="LP386_001811"
     CDS             complement(8884..9600)
                     /locus_tag="LP386_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBL1919046.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(9601..11424)
                     /gene="glpO"
                     /locus_tag="LP386_001812"
     CDS             complement(9601..11424)
                     /gene="glpO"
                     /locus_tag="LP386_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HBL1919047.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(11438..12934)
                     /gene="glpK"
                     /locus_tag="LP386_001813"
     CDS             complement(11438..12934)
                     /gene="glpK"
                     /locus_tag="LP386_001813"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBL1919048.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(13070..14530)
                     /locus_tag="LP386_001814"
     CDS             complement(13070..14530)
                     /locus_tag="LP386_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1919049.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(14520..15815)
                     /locus_tag="LP386_001815"
     CDS             complement(14520..15815)
                     /locus_tag="LP386_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL1919050.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVKEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(16147..16824)
                     /locus_tag="LP386_001816"
     CDS             complement(16147..16824)
                     /locus_tag="LP386_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HBL1919051.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(16854..17945)
                     /locus_tag="LP386_001817"
     CDS             complement(16854..17945)
                     /locus_tag="LP386_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HBL1919052.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(18046..18480)
                     /locus_tag="LP386_001818"
     CDS             complement(18046..18480)
                     /locus_tag="LP386_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL1919053.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(19064..20521)
                     /locus_tag="LP386_001819"
     CDS             complement(19064..20521)
                     /locus_tag="LP386_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL1919054.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENL
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIEDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(20518..22413)
                     /locus_tag="LP386_001820"
     CDS             complement(20518..22413)
                     /locus_tag="LP386_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL1919055.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPITLLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSPVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(22471..24246)
                     /locus_tag="LP386_001821"
     CDS             complement(22471..24246)
                     /locus_tag="LP386_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBL1919056.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARLPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYLVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESSEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(24296..25792)
                     /locus_tag="LP386_001822"
     CDS             complement(24296..25792)
                     /locus_tag="LP386_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL1919057.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     EIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRIWKEEDCAPVMLDGDEQYLQANTVDYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(25986..27608)
                     /locus_tag="LP386_001823"
     CDS             complement(25986..27608)
                     /locus_tag="LP386_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBL1919058.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESINAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTVPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
BASE COUNT         7820 a         5949 c         4596 g         9244 t
ORIGIN      
        1 tttgtctcgc ttaattatac aaacggcgta ttcaaaagat ttatttactt ttttgtatag
       61 atttcgattg ttccacctag tcaatacaaa tgaggtaatc aggaaactga aaaaaatcaa
      121 tacaaaaaag ccgattaaga aatacagcat tttcttttct gataaaaaag cgtacaagga
      181 aaaatccttg gctctttctg gtctcgttaa tgggaaaaag acccatataa aaggaagaac
      241 aacgatcatc catcctaaaa gagccactaa cgtttgccaa atctttaacc agtaattacc
      301 ttttgaaaaa tacttatctt tcaccaaaat tgatgcaact tcttctcttg ttactttttt
      361 catatcctca cctcacgttt ttttgttacg acgtaggagt ttaccataca tttcatttct
      421 tttcacataa agtgttccta aatttttcct aagaaaaaga acaaaacatt tctcatcagc
      481 aaatgaaaaa tattttgttc tttttatcag ttgttctttt tattttttat ctcttaatta
      541 tgttgctctt tccaatacga caatgctttt cattcctcta gatatcgccg tgtacatttg
      601 tctgcgtctt ctttgctcat ctccatcgtt ttcaaatgga tataagatta catgatcaaa
      661 ttccagtcct tttgctagac tcaaaggaat gatttggcag ttttctaatc catatgaatt
      721 ttttttaatc gattcttgta gcgtttgggt ttcctcttct gtttgggtga taactgccgc
      781 tttttctcct tttagagaaa ccaaaatctc agctagtatt ttcaacaatt cttcagagga
      841 tcgaaaagag cggtattcgg gttcttttcc ttgcggtcgg atcgatacga tgtcgatctt
      901 ctcttgatcc acagcatagg ttttgaaaag ctctgtgatt gctccgctag aacggtaact
      961 atttctaaga tcataccgat ggatcggcag atggtagtca tcgaaacaac gcataatatc
     1021 agcaaaagta gtggaagaat taaagattgc ctgattctcg tcacctacta aagtaaagtg
     1081 agtttttgga aataattcga tcaatagacc taattgtgcc agggtataat cttgtacttc
     1141 atcaatcaat agatagcgaa atgctggtac atttaccttt tcaacaagta aatgacgaat
     1201 agctaatata atgactgctt catcaacagt acgtgtgggt tgccaagcat aagctgagcc
     1261 atatcgtttt tcataaattc tttcaaacaa ctgatgctca tccacccatg ccatttcttc
     1321 gatttgtctg gttatttttc gatatttttt ttgtaaaagt ttccttgcat aagctacaat
     1381 actttgttcc gaatcatcag aaatcaattt accgaataat tccaactgcc tatcttctgt
     1441 caacgagagt acctgattct gcacagcagg actttttgct tgtttcaaaa gatgattctt
     1501 ccattcgctc atcagtgcct ttttcgttgc ttgaagccta tcgatcaatt taggatgagc
     1561 aggaactttc tcatatattt tttcgatcgt ttttttagaa aggactgttt ttccattttt
     1621 agtaagtcca cggataaaat tcggatgatc taaaaacaaa ggatctgatt gttttagatt
     1681 atcgataaac tttttgctac gcaaacgttc tgtctgctcc gatacatttt ctcccgtgat
     1741 acgtttgaaa taagcctctt caccttctat ttcctctgct gaaagctgtg aaaccagctg
     1801 tatgatggtt agattcagtg gatttctttc acctaatgat ggtaggacat tcgaaatata
     1861 gtcgataaac cgatgattag gtgatagaat cagcaagtca tcggatgtca tcgtatctcg
     1921 atataaatag agcagatacg caatacgctg catgatagca gaggttttac cacttcctgc
     1981 tacgccattt accaagatat tttgactttt cacatcccga atgattgtgt tttgttccga
     2041 ttggatcgta gcagtgatag ccttcatttc attggtctca tcttggccta agacttctaa
     2101 taatacgtca tcttgaatag ctacagacgt atcaaaaaac ttgaccaaac gatctctttc
     2161 caaaagaaat tgtcgtcttt ctttaataac cgtatcgatt ttattttgac gaaccgtata
     2221 agaagatgga ccaatcatgt tattgtaaaa aagttcggca attggtgaac gccaatcata
     2281 aacaagattt tcatctgcat catctgtgaa atttgctgta ccgatataaa aggattcttt
     2341 tggctcatta tccagaaagt ctacaacgac ttttccaaag tagggacttt tcaataaacg
     2401 ttcgatcttt gctagctgat tttctgcgtt tttctgtttg atattcatct gatcgatttc
     2461 tctatttttc atttcaatca tcgaaaaagt atccaggtta tctaagtaac tgtcaaaatt
     2521 caatcgaagc tcgccagcca tttctttcaa cgactggttt ccttctattt ttgccgtatc
     2581 catcgattcc cgcagttcgt tttttttatc aattagcttt tgatacacgt tcttcagata
     2641 tgcttcttct aactgttttt gtgtgttgac catacacatt ctcctctttt tttaaagtgg
     2701 tggaaccgat tagtttacct cttttaagag tcgaatgcaa gctttttaac gagtatcatt
     2761 tgttaggata tatcagttct tcaggtcgga cagtttgata taaagaaaat gcaccatcaa
     2821 ggttttttac gtggtagcca gactgcttca agattctttc cgctagatag ctacgtaatc
     2881 cgctatgaca gctgacgata tattcttgtt ggctgtctaa ttcatttaat cggtcccgaa
     2941 gttcattcaa agggatatgt ttggcttcct tgaatttgcc cttttccaat tcttctgctg
     3001 ttcgcacatc taataaaatt tttccttttg ctagttctgt cggcaattca tgccattgta
     3061 cggtttcact aagcccttct gcaatgttca ttgctgcata tcctagcatg tttactggat
     3121 ctttggctga gccaaatggc ggtgcatacg tcaattctaa ttccggtaaa tcgaagatcg
     3181 tcaaatgccc tttgattgct gttgctaaaa tatcgatccg tttatccaca ccttttgccc
     3241 caacaccttg tgcaccataa atctcgccag tctctggatg gaagatcaac ttcagtaaaa
     3301 tatctgttgc ttctggataa tagcttgcat gatcttttcc tgatacatga atgacttcaa
     3361 aagacagttc gttttctttg gctgttcttt cacttaaacc ggtggatgcg gcagtcattc
     3421 caaacgttcg tataattgct gttccaatac cgccttgatt tcttcgagaa attccggaaa
     3481 tcgtgtccgc aacttgtcta ccttgacgat tggctggtga agcaagagaa ataagtgcat
     3541 cttttccagt gatttgctgt tttacaacga tagcatcccc caccgcataa atatcaggaa
     3601 tattcgtttg ataacgttcg tctactagga tacccccgcg tatgcctaat tcgattccag
     3661 cggtcactgc tagctggtta tcaggacgaa caccaatgga taaaataact aaatcagcag
     3721 ggatggtacg cccatcatcc agtcgcaatc gtttcccgtg gtcttcaaat ccagcgacag
     3781 catgagaagt aatcacttct actccttgat gagacaattc tttttctata aaagctgcca
     3841 tttcttcatc cagtgttgga agaatatgtg gtgcttgttc gatcaccatg acttctaaac
     3901 ctcttctttt taggttttct gccatttcca atccgatgaa tcctgcacca acgatcacgg
     3961 cacgctttgg ctgtttttct aatgcatgca tcactttatc gatatctggt acatttctaa
     4021 tagaaaaaac attgtcggct tctgttatcc ctggaatcga tggaacaact ggttttgcac
     4081 caggagataa aaccaatgca tcgtactgtt caatgtgttt ttgaccctca tgtacgactt
     4141 ctaccgtttt gttttcggga aagatggctg tcacttcatg atttggacgc acatctaaac
     4201 aaaaacgagc ggataatgat tctggcgttt ggacaagaag attttcccgt tcactgattt
     4261 ctcccgaaag ataataaggc aagccgcaat ttgcaaaaga aacatacggt cctttttcaa
     4321 aaacaacgat ttctgcatct tccattaatc ggcgaagccg tgtagcagca gacattccac
     4381 ctgctacacc tccgacaata acgattttca tcttatttcc ctcctactgt tcgatcaaac
     4441 cattgattca tgccaccacg tacattcact acatcataac cagatttctt taattcttta
     4501 gctgcttgtt tactcctcat ccctgattga caaatcacat agacggtctt ttctttgtct
     4561 ccatcatatc tgtttatact ttgtaatgga acatttttag ctccttttat atgcccgccc
     4621 cggtattctg caggtgttct aacatcaagt aacgctggat tttccaaaat cttttccttt
     4681 aattctggga ctgttatcga ttttattgat tgaaatagca aattcatttt ctgcacctca
     4741 tttacatttt tataaatacc tcatggggta tattaaacag gagctttatt aatatgtcaa
     4801 ccagaatgac tcttcatttt tttcactact ttttatattt gcataaaata ccgataaggg
     4861 gtattatcta attataaaaa tagaggagaa tgtgttatgg agattgataa taaaaatatc
     4921 ctgaaccgtt tgaaacgtac agagggacaa attcgtggta tccaaaaaat gatcgaagac
     4981 gaaaaagaat gtatggatgt catcactcaa ttaagcgctg ttcgttctag tattgatcgc
     5041 gtaatgggca tgatcgttgc agataatctg aaaaattgct ttgagaaacc tgatagtaat
     5101 ccagaagaac aagcggctaa actagaacaa gcgatcaaga tgattattaa aaagtaaagg
     5161 aatgatttca atgaaagtcg ttttccatat tgatgaatta gaaaaatggt cagaaacagg
     5221 gaaaaacgta aaaaacctga taaaagcttc tccagaaacg acgattgtcg tatctgtaaa
     5281 tggcatcgcg attaccggtt atctagactc tgccaatgca gaattcttag atttgcaagg
     5341 agtcgttttt cacgcttgcg ccaatgctat gcgtgctaat catatttcag aaagttcttt
     5401 acctgaacaa gtaatcgttg taccagcagg tgtccttgat ttagttgaac tgcaatccca
     5461 aggttatgct tatatcaagc cttagtcagt agaggttgcg acagaagtga tcagcttcaa
     5521 gaaatttcgg cttatttttc gaagaagcta cttctggaaa accgtgaatc aaaggttgtg
     5581 aaaacgctgt cctgcatcaa gtaataagaa cagccaaaca aaaatagctt ctcatatttt
     5641 tcgtttggtt gggcttatta ccgcagatgc aagcttttga acaccgttta aggaagaggt
     5701 tgtgaaatca gcggtttgac ctaagtatta gagaaaaaaa cgggaaaata gctcctcata
     5761 ttttgccgtt ttttgagcta ataccgaagg tcagctgatt gaacaccgtt taccaagagg
     5821 ttgtgagcct accatttaac tccgaatcac aagaaataat ttcaaaaaca acttctcctg
     5881 tttttggttt ggttggctta ttatcgagaa gtagctactg ggagtctatt tatcaaaaaa
     5941 aggaatgcga cataggtcac accccttttt tattttcttt gaaacatctt tcggtactcg
     6001 acagcataca agacaaaaga ttgtaaaaga ccgtaagtga tgacggcaaa aatgactctc
     6061 acccacagcg ttggtaattc tgggaaaagc agcaaaagga tcatgccaac atagatgaca
     6121 gcagtcgcta ctttgccata ccacttcgct ccacttaatt tgatattttt agatagcccg
     6181 attaatccag ctacaaacat aaagccttct tttatcaaga atagaccaaa caacagccaa
     6241 agccacggtc gataccatgc catagacaaa atcagaaaaa gttgtgtcaa tttatctgca
     6301 aacggatcaa gcaccttccc taagtctgtt acctgattat atctccgagc aatgaccccg
     6361 tctagataat cagacaaacc tgagacaaca atgaccgctc ctgctatata aaatgactgt
     6421 ctcagcacaa aataaagata aatcggcagc aaaaaaatac ggaatatcga taaaagattc
     6481 ggaatcgttt gtatttcttt acgccagtct gtgcttaatt tcattttatc gccctacctc
     6541 ctcagcactc ttttcttttt attttagctt acacggggaa taaaaccaat gatttcactg
     6601 tttttatttt tctttacagc cactgatatt atgagctaat ttgagataat cacttgctgt
     6661 tttcatcgtt tactcttctt tcttcctgtc gtttgcgcat ttcttttact agtactttat
     6721 gagctttttt tgatcctcgc tctaggtcac gctgccgttt acgtgtttta taatcgataa
     6781 acagactgtc taaatcgtaa cctgtcgggt acagatcttc tgctgaacgc accagacgaa
     6841 cacgctgacg aggcacgtgg attatttttt tgtctaaata tacatcaatc gtatcttcac
     6901 ctatatcttc ataaactaac gcttcttttt ggtattcatt gacaaatatc cgatcacctt
     6961 ttgcaaagag ctggcgttct tttttattct ccttcctatt tgtaactgct gtcttaggaa
     7021 gaaattcttt tttctgtgtc cgataggctt tttccgccaa gtaacgctct gcttgatgga
     7081 tcaatttcat cgacatatcc attttatgag caatccacaa agcttggctt tctcctgttt
     7141 ctccaacccg caactgatat ttaggacgaa gtgcttcccg atcgaaagcc atagcagccg
     7201 gcacaaaatc ttcatgatct ccggcgaatt tcttgatttc tccataatgg gtcgtggcaa
     7261 tgatcaatgc cccttgctca tacatagatt ccatgattgc gatcgctagt gcagcccctt
     7321 catttggctc tgttccactg ccaatctcat ctaaaagtac caacgtattc ctttttatct
     7381 ttttcaaaat agcagcgatg ttttgcatat gaccagaaaa tgtactcaac gcattttcta
     7441 aattttggtg gtcaccgaca tcgacgaaaa tctcatcaaa gacagcaagc tctgtccctt
     7501 cttttgccgg aacttgcata ccgaacatcg ccatcaaagt caataaaccg actgtcttca
     7561 acacgactgt tttgcctccg gcatttgctc cggtgataat caagcctcga tagtctttac
     7621 cgatttcaac atccaatggt accgcatgct caggtaaaaa tggatgtctg ccttgcttga
     7681 taatgatatg ttccgattta ttgattctag gtgtgcttcc attgatttct cggctaaatt
     7741 ttgcccgagc aaagatgata tctaacaccg tgatcgtttc gatcaataaa tcgatcactt
     7801 cttcgttttc tgcgatagca ccagtcaatg ccgccaggac ttgatattct tcactgattt
     7861 cttcagcttt taacaactga tagtgttcat tcaatttaga aatcacagtt ggttcaataa
     7921 aaaccgtcgt tcttttattt gattcatcga taatcgttcc atctatttta tttttatagc
     7981 tggctttgat aggaatcgta tagtattcgc ctttttgaac aatcattgct tcttggatca
     8041 tttctttgtt tttcggatga cgcaagaatt tcagtaattt tgactggatt tctttttcga
     8101 ttagttgtaa ttgtttgcgt actttacgca aattacgtga cgcgtcgtca ctgactttat
     8161 tattttttat tttctggtca atcaactctt ctacatttat caaatcagga agatgtttgc
     8221 tataagcaaa caacaagggt gtctggtatt gattcttatc aaaaaacttt gtgatcatcc
     8281 gactgcttct aagaaaatcc gcatattcga tcaaatcggt tggctgcaga atcaaccctt
     8341 ttttgacttg ttctgtcagt gcatcgatcc tcggcaaccc cataaatgga acatgctgac
     8401 tgctttctaa gatcaagcgt gcttctcttg tttcttcttg acgatccaag acagtttgta
     8461 ggtttgtcga gaccgtcata tcgctgattc gttttttgct atagtttcca attgctcttg
     8521 cttggatttc ctttttgatc cgatcaaatt gtaattgact aatcatttcg ttgtccatat
     8581 tctctccttt tcttgaagag atacctgtcc caaaataaat aagggcctag agataaataa
     8641 aaggatagaa cacagcttaa aaaagtcatg tcctatcctt attagaatac aaagatattg
     8701 ttttcctgac aggtaccgtt tcataagcac accaaataaa ctttgtttat tggctattcg
     8761 acttactgat tagataccag ctacactcac aaaacatacc ccattcttct aggtcttatt
     8821 tattttccac ttaactatag caagacacat tttggttgtc aaactttagt atgttttata
     8881 gatttacacc attaatgaat agacacctac cgcgataatt gctccgatca ttggacctgc
     8941 gattggtacc catgaatatg cccaatctga agttccttta ttagctattg gcaataccgc
     9001 atgtgctaat cgaggaccaa agtcccgagc agggttgatt gcatatcctg ttggccctcc
     9061 taatgaaaga ccgatggcta agatcaatcc acctacagcg aatacgttcg ttccaggtgc
     9121 aaattcgttt tgtccaaaag ctagcaaccc aagaactaat acaaatgtac caattaattc
     9181 tgtgatcaca tttgctggat aattccgtat agcaggacct gttgcaaacg ttcctaaaat
     9241 cgcgctttca tctttcgttg cattccaatg tggcaaataa gaaagccaaa caagaatggc
     9301 ccctgcaaaa gctcctaaaa cttgcgcaat gatgaaagga acgacaagat tccaactaat
     9361 tgcccctgtc atcgccatag ctagagagac tgcaggattc aaatgagctg ggcccatgaa
     9421 tccagaaata tagacagcca ttgttacagc gagtccccaa ccaaatgcga tgacaatcca
     9481 gccagaagcc tgtgctttac ttttgtttaa attcacagcc gcacacacac catctccaag
     9541 caaaactagg atcagtgtcc caataaactc ccccatgatt tgagtcatat cactgttcat
     9601 ttatttctcc ccctttagtt cccgcagatc tgattctgca atcaatgctt ctaaacgttt
     9661 agtctgttgc gccttctcct cttctgtcca ttcaaaatat ccagcaattg catcgatcac
     9721 aggttgcttg atctcatcaa gctgatctcg ttcaaacaac agatgatttg tacgacgaat
     9781 gagataatcg cctggggcca aaaccatttc ttcttctaaa ccataacgta accgagctga
     9841 ctcagcgaga ctcaaaccag gataaggtgc catttctttt gctaattcaa agatacgtcg
     9901 ggcattagtc ccgtaaaaat cagcgatata agtagcatct tcttcctcta aaccggctgc
     9961 tactccttct tttgctaatt ctgtcactgt ttcttctaat ttagttggat cgaagtttcc
    10021 acctgaaatc tgatattttt tagagtcgat ttctttcgtc tctattccgt attcttcttt
    10081 taataattgg cgtatcaatc gcaaagctcc ttctgccatc ttacggtaat cggtgatttt
    10141 cccaccagat aaagtcagca aaccatctgg ttctctttct aaagaactac ctctggaaat
    10201 cgtagaaggt gctttttcat cacggctgtt ttccaaatgg ttcaacacgt cttctacttc
    10261 agcacgagaa actttgtttt ccttatattc acttactgta tcgacaactt tattgaagct
    10321 cttgtctgaa atcgatccat tatctccacc attgtaatca gaaccagaat taccaatcaa
    10381 cagtggacga agtcctgccc agcttgcttc gatatcattc aatgtgatat ttgcttctgg
    10441 atagcgatga ttgatcacat ccaatagata atctacatct tcttgtgtga ctttcggatc
    10501 cgtaaaatct ccttggtaat ccgtatctgt cgtaccaaag taagtcttgt tttctcttgg
    10561 aatagcaaaa accatccgcc catcttgctt tcctgtatcg aagtatgtgg gttgcggtac
    10621 aggcagtttt ttcgcatcta caactaaatg gatcccttta gttggacgca ttttaggaga
    10681 gactggacgc gtaaaattca agtttcgtac tttatctacc caaggaccac tcgtattgat
    10741 cactaatttt gctttgattt cgatcacttc atctgtcagc aggtcacgag ctttgacgcc
    10801 aacgatttga tcgccatcat ataaaaagcc aaccgctttc attttactta ctagataagc
    10861 cccatcttcg gcagcctttt tgatattatc aatcactaaa cgggcatcat tgttgcggaa
    10921 atctagatag acacccgcgc cttttagccc ttcttttttc aaaaacggtt ctctttccaa
    10981 tacttcttct ggtgtcagcg tataattctc atatttggtt cctgtcacat ttgccagttt
    11041 gtcataaagg tccattgcta ctttgaccga gaacatattg aaggttgttg ctccttcgcc
    11101 ctcatagatt ggcaaaagca ttggatctgg ttttgggatg tgtggggcaa tactttgtac
    11161 gactgcacgt tcaccaactg tgtcagctac tacttccaca tcaaatgtct tcagataacg
    11221 aataccgcca tgaacaagtt tggtcgagcg agaggaagtc ccttctgcaa aatcctgcat
    11281 ttcgatcaat cctgttttga ttcctgatgc tgctgactgg actgccacac cggcaccagt
    11341 gattccgcca ccgatgatca acagatccaa ttcttcttgc tgcatttttt gaatgctatc
    11401 ttgtcttgtc ttgtttgaaa acatatggat ttcctcctta ttcaaatgct tgggtagctt
    11461 ttactgcttt tttccaaccg ttgtaaagtt tttctcggcg ctcttcctcc atttgaactt
    11521 caaatagctt gccagcttca taaaattcgc ggatctcgtc tgtatctttc caataaccga
    11581 cagctaatcc tgctaaaaat gctgccccta gcgccgttgt ttccaagttt tctgctcgtt
    11641 ggatcggtac attcaagata tctgtttgga attgcatcag atattcattg tttgctgcac
    11701 cgccatctac tttcaataca ggaatcttga ttccagtgtc atcttgcatc gtatcgatga
    11761 tatctctcac ttgataagca atcgactgta aagtagcttt aatgatatct tcttttgtcg
    11821 taccacgtgt caagccaaac atagcccctc gtgctgcctg atcccaataa ggagcaccta
    11881 gcccaacgaa tgcaggaaca acataaacct catcttcgct tgtagagcgt ttcgctgcgt
    11941 cttctgaatc gctagctttt tgcaacattt gaagtccatc tctcagccat tgaatcgaag
    12001 aaccagccac aaaaatactt ccttctaaag catagtaaac ctttccattt atgccgtaac
    12061 caattgtcgt caataaatta tttttggata attgcggttt ttcaccggta ttcatgacaa
    12121 taaatgaacc tgtaccataa gtattcttga ccatgcctgg ttcgaatgcc atttgtccga
    12181 ataatgcggc ttgctggtct cctgccatcc ctgaaattgg tgcttcgctt ccataaaaat
    12241 gataaccttg cgtataacca taaacttctg agttagaagt gacttttggt aacatcactc
    12301 gaggaatatt tagtaaatct aaaatctcct gatcccaatc tagctgatgg atattgaaca
    12361 acatcgtccg actggcattc gagtaatcag taacatgtgc ttgtccatcg gtcagtttcc
    12421 atactaacca agaatcgatc gttccaaaca tcaattcgcc tttttcagct cgttcttgcg
    12481 cgccttctac atgatcaaga atccagcgta tcttcgttgc tgagaaatag gcatcgatca
    12541 ctaaccctgt tttttcgtgg aaaaattctt gatagccttc attttttaag ttatctgcaa
    12601 ttccagctga ctgtctggat tgccaaacaa ctgcatgata gattggacgt cctgtatctt
    12661 tttcccatat tactgttgtt tcacgctggt tcgttatgcc aatcccagca atctgatttg
    12721 gtttgatccc tgattcgatg aacgctccgg caataactga ctgtacagaa ttccagattt
    12781 catttgcatc atgttccacc caactttctt gcgggaaata ttgcgtgaac tctttttgag
    12841 aactgccgat gtgtcttcct ttcttgtcaa agataattgc tcgtgagcta gttgtacctt
    12901 ggtcaatcgc catgatatac gttgattctg tcattgtgat tccctccatt atatgcaaac
    12961 gctttcttta actactctta tcatactact gttttaaaaa aagaaactgt caaaatttta
    13021 ttcttttttt ctttttttga cagtttttta ttatgaagct attttttaat caattctttt
    13081 cttttttcag cgtctctatt cttcttttca atcgaataat gtcgtaaggt gacgcaaatt
    13141 ctgacagata atattcacac tgttttttgt ttctctggca aaatgtgatc accaaatcat
    13201 attctttacc ttcttcataa cttccaatct caataccgcc gattcccctc agttctctga
    13261 tcagatattg ttgaaaagca atacgataaa tcggcagact ttctaaatcg attccaatca
    13321 ctactggttt tgcaatataa aaatcgatca tcaaaagaac attggcatac tggatcatca
    13381 ggtaactaag ctcactatct tcagctcttt tcctcggcaa ttgctgcacc gctgtttcct
    13441 gtaatttcgc cagtaactgt gttaaggaat gcccgagcat tttctgctgc tgttccaaaa
    13501 gccgatcacg ctcatagact tcgatctttc caacaaagaa aaaccattca ttgttgatct
    13561 gggaaatttg gtagcctact gccttttctt ctttgatttt caaacgacga ggacgataat
    13621 gccataacat cgtttcccga atgtaagtat ctaaaacagc ggttggtaac tttttgctcc
    13681 gtgtcaaatc atactgataa aatatttctt cgtctactat cgaaaaagaa acaaaaaagc
    13741 tgtaaaacat cattgtttcg tatacattca gttctgctgc tgttcgacta agatgcatca
    13801 cgatgattgg atcgattgct tgataaagcc ggtccgactg atagagtaat ttcttttctt
    13861 tcaaagttgc gtacgtactt ttttcattca atagtctttt tttcgtaatc ccgagccagc
    13921 aagcaatctg tgcttctgct gatgccgtaa acgttgtttc taatacacgg tccaatccta
    13981 gaatgaacgg tcttttttct ggtgtatttt gcaaaaaaag cggtcgctga tcttccggga
    14041 tatattggaa tagttcataa taaaaatatc gtatctgtag ctcttctccg tataattgac
    14101 cgtttttgat ttgtaatcca aattcctcta agagctggtt caattctttg atctttcgaa
    14161 aaacagaaga ctcactgata ttaaacgctg tcgctaatcg aacgatggat acttgctgat
    14221 gttctaataa atagacgagc atcttaaact tcaagctttc ctgcaataaa aacaatagaa
    14281 ttttttccaa acttacatct tcgtccaaca caagcagcgc ctgatactca tttcgctgta
    14341 cttctacttt tttttccatc attcggccaa tcaattcaat atcttccaaa tattgatcaa
    14401 acgaggcttt tgacagttgg acatgctctc tcaaaccatt gatagaggct gttccccctt
    14461 gcagaacaag gtttcgcaaa atcaggatct gtaactgctc ttttctttct aataatgctt
    14521 caatcttcat aggcagtatt cgccaccttt gaccacacca tatctggcac acggtattct
    14581 ggctggaaaa atagctcatg ttcttctaac tgttcaaacg tccatccttc ttttactgca
    14641 attgtcagtt ggtcaagaag gtggaacatc tcttttttgc tttggagctg tgctccaaga
    14701 atcttttttt cagaatcaaa tagaaatttg agtttaactt tgctttgatt tattgctgta
    14761 agcttgtagt ctacgtatcc tgtttcaatt ttttggggat aaaaaatgct ctcttcttct
    14821 gtcaaaccta cgcttcctaa gaaatagcca aaccactgat tgccgactgg acgataggtt
    14881 ccctgatcct ttgtctgtga gccactaatt gtcttgctga catttcgtgc tgtacggaca
    14941 gcgttattta ctagagaaac atacattttt tcatttgttg gacgaaaagt tacttggatc
    15001 gcatcgccaa tcgcataaac gtctttttga gacgtttgca agtagtcatc tacccagatc
    15061 gttccatcat cattcaatgt taattgttct tcccacatct gattgtcggg gcgagaatga
    15121 ttagccagca aaacaagatc atagttctcc tttctttttt ccgtctctac aatagcggtt
    15181 tcattttcgg tcaaagacac aacttgttct tctaaaaaaa gtgaaagccc ttgatttttc
    15241 atttccttta ctaacggttc tgtcatttca ggatctagat aacgaaaaag aattgacttt
    15301 cggctttcgt aaagatggat ttgttttttt cttgatgcca acccttcagc tatttcgatt
    15361 cctgcttgtc ctgcaccaat aattgcaatt ttctttgcat tcatgatctt ttgctgaaga
    15421 gccgttacgt tttgtatctt tttaactggg tgaataagcg ttgattctgc agaaatattt
    15481 cgaaactttt gatttgaacc agtcgctaga atcaaacgat caaaatccaa tttttttcct
    15541 cctgctaaaa cgactttttt ttctttcaat cctattactg tcttttctgt gtaaacatgg
    15601 attcgatagc ggtcagtcag ttcttctttc gtgatccaag aaagttgttt ttcactggta
    15661 acctttcctt ttaatatcaa attgaacccg ctgggaatcc atcctaactt cgattgcttt
    15721 tcaatcaaat atatttcact tgttggcatc aattggcgaa gataaatagc cgcatgaatc
    15781 cctgcaaacg acccgccgac aattacaatg ttcatctgca ttcctctttc ttataaggtg
    15841 ttctactgct aacttctcaa tcagaaaaca cagtattcat aactcgcttt caaccttatg
    15901 atacatagcg atgcagcaga atcaaccctc tccatcatac cgtgttctag gtctgcttct
    15961 caataatgta ctagtggacc taattgaaga gtatcatttc tgaagagatg tttcaaaaaa
    16021 tgtactctta taaaagaaaa aaactcgcct tttacgtacc tctgtccaaa taggaaacag
    16081 aaaagaacga aaagacgagt tttagcgtgt gtaatgtaat agttagaata gacacatcat
    16141 ttatttttaa ttctttaatg cttcaacaac tgcttcgcct aattgatgag cagattgagg
    16201 attttgccct gtaagaagcc gcccatcaat ttgaaccact tctgaaaaag ctgctccaga
    16261 ctgatagttt gctccttttt ctttcaaagc atcttctgct aagaatggta cttcattcgt
    16321 tgtaccattt gcttcctctt cttcattact gaacccagtc actgtacgtc cagctaaaat
    16381 agattttcca gactcatctg taactggcaa caatcctaca acaccgtgac aaacagctga
    16441 gaccagccct tcatttcgat agatttgtga agcgactttc ccaagatcta ttgcttctgg
    16501 aaaatcccac attgttccgt ggccaccagc ataataaacc gctgcataat catttgcatc
    16561 cacatcatca ggacgtaagg tatttcccaa ggcccgattt ctgaaatctt catcttcata
    16621 ataggcccaa tcgatttcat ccatattcaa aacactttgc ggttctaaag gtacatatcc
    16681 gcctttagga ctgacaaaat ctgcatcgat cccatttttt actaatacat cataaaaatg
    16741 agtcagttca cttaaccaca aacctgtagg acgctcgatc ttttcgtact tttctacatt
    16801 tgttaatacg atcaatactt tcattttccc atcctctttc tataaaaatt gcgttattga
    16861 taacgtgctt tcaagaaatt atataatggg cttggcaaat aaagctcttt atatgcttct
    16921 tcaaaaggtt tcgttacaaa ttcatcctca cggttttcca ataatttctc tgcccagtca
    16981 ggatcgacga tcatttgctg tccaattgct gcaagttctg catatttcaa tacctgctct
    17041 acatcttcgc gattgcggat cccaccgaca ccaactaaag ggatctttcc ttgaatcgtg
    17101 ttatggacca cttcaagaat cgatttatcg ttgtatttat cagaacgagc tattcgatca
    17161 tacatattta atgaaacatg cagataatct agttttgact cacgtaatcg ttcaagaagc
    17221 cagatcgtgt cttcaaaacg gatacctggt gtttcatatt cttctggtga gaaacgatac
    17281 cctacgatga atggtttttt agcatattgt tcaaccgctg agaaaaccgt tgttaataat
    17341 tcttcaataa aacgataacg attttccaag ctaccgcccc attgatcctc tcgtctattc
    17401 gaatgcggag agaaaaattg ttggatcaaa tacgtatttg ctccatgcaa ctcgattcca
    17461 tcaaatcctg attcaatcgc tctacgtgtg gctttgccaa atgcttggat tgtttcaacg
    17521 atttcttctt cactcattgc tcgtggtgtt tccgcatcag gacgttttgc tgcaactgca
    17581 cttgcagata caggctgttc tccagataaa gttgctcgac ttgtcattcg tccaccgtgg
    17641 aaaatctgaa taatcgcttt tgcgccttct ccttggattg ctttcgctag ctcacttaat
    17701 cgaggaatca tttcatcatg agcgatgctg agttcacctg gccagccttt tccgatatct
    17761 tggacatttg cagcaccagt aataacagca ccaagacctt tagaacgttg tttataataa
    17821 gtgatctcat cttcggtgat cactccattg aaaaagctga gttgtgtcgt cataggcgac
    17881 agcatcaatc ggttcttcaa ttgaactcct gaaggtaaag taattgattg atcaaattgt
    17941 gacattgtca ttcctcccat aattcgctct gattaaccta tcgagaatca tctatcatta
    18001 aaccactcga ttagttgtac atgcaactaa tttgcttaaa aaattttatt ttttttgtaa
    18061 cttatctgtt gcatcattca ttgtctgggc taattcttta cttgcttcat ttcccaaaac
    18121 tgctttgtat gactgatgaa gttcttccca gctaccatcg acttccttag caaattggcg
    18181 tccttgttct gtaagataaa ctaatgacaa gcgaccttcg ctaactgttt tgacgtatcc
    18241 tttatattct aatttttcaa caaaacgagc aatcgttgat ggggcggaat agagcatttg
    18301 tgcaatatct ttttgtggta ttccatcttt ttcttttaat atcaataaaa taaaaccata
    18361 agttggtgcc agacctgtcc ttctaaacgc ttcatcagct aatttattca acatgcgatc
    18421 tagctttttc acgctaaaga aaagacattc atctaacgct ttttcaattg gcttttccat
    18481 ttcatcccct ccattggcgt acatatcata gtatgatttt tattttttgt caaaaaacac
    18541 ggaataatgt ccgcctcctc tgtctagatt tgaaaaaaag aagtagccat cttcaaagaa
    18601 tttcggcttg ttttcgacaa aactccttct ggaacaccgt gaatcagagg ttgtgaaaaa
    18661 gtcgtttagt tttgagtatg aagaaaaatt ttgtgaaaat ggctttccac atttttgcat
    18721 aaatttggct taataccgaa aaactggctt ttgaacaccg tttatatcag aggttgtgaa
    18781 aaagccgtcc tgcatcaagt aataagaaca gccaaacaaa aatagttcct catattttgt
    18841 cgttttttga gctaatgccg atggtcagct gattgtacac cgtttattga gaggtcgtga
    18901 gcctgccgtt gaactccgag tcacaaggag caatttcaaa aaacagcttc tcatgtttta
    18961 tgactatggt gacttgtgat cgaggagttg gcaggagaat actgtttatt cgtaaagaag
    19021 gggctgtgac aagacttttg tcacagtccc ttatttcctt ttattatagg atttcgccat
    19081 ttgattggat gacttgtctg taccaatcaa atgatttttt ctttaaccgt ttctttgtgc
    19141 cattcccttc gtcatcttga tcaacataga tatatccata acgttttgac atttgtgaag
    19201 tagaagcgct gacgatatca atgcagcccc acgacgtata accaaataaa tctactccat
    19261 cttcgatagc ttccttcatc tgctcaatat gctgcttcaa atagtcaatg cggtaatcgt
    19321 cttgaacggt tccatcttct tctactttgt ctatagctcc gagtccgttt tcagctatga
    19381 acagtggttt ttgataccta tcatataatt gattcaaagc aattctcaaa cccttaggat
    19441 caatctgcca gccccattca cttgatggaa gatacggatt tttaattcct ccagttatta
    19501 agtttccttg gaccccttcc aaattttctg gatgagcact gactgcacta gacatgtagt
    19561 agctaaaaga aacaaaatca acagggtagg ctgctaagat ttcttcatca cctacttcta
    19621 tttttaagtt gacacctttt tcttcaaaca ttcgttgcgt atacgctgga taatatcctc
    19681 ttgcttgaac atcactaaag aacaaagaag ttctttgctg ctcaattgtt ttttgaatat
    19741 catccggatc acaagaatac ggaacaagaa gctgatagct gatcatacaa ccgacttgtg
    19801 aacctttgat aatttcatga caagcttttg tagctaaagc acttgctata aactgatggt
    19861 gtgcaccttg gtatttcgct tgttccaaat ggggatggtt ttcttcaatt actcctacgc
    19921 taacaaaagg gtgatgtttt acacagttga tctcattgaa agtcatccaa tattttactt
    19981 tatttttata gcgtttgaat actgtttcag cgaaacgaac gtaaaactga ataagctttc
    20041 gattaggcca tccaccatat tctgtaacca aatataacgg catttcataa tgggaaagag
    20101 aaacgactgg ctcaatccca tattttagac attcgtcaaa cacttgatca taaaaaaata
    20161 atcccgcttc attgggtgtt tcttcatcac catgaggaaa aattcttgtc catgcgatag
    20221 acatccgata gcatttaaaa cccatttcag caaataaacg gatgtcttct ttaaagtgat
    20281 gatagaaatc atttccgtgt cttttaggat aataatactt gctgttggga tcctgcgccg
    20341 cttttacttg ctgatgcgtc atcatatgcc attgatctgt ccatttttct ttaggtaaat
    20401 cgctgtcgaa tgtatacaca tcagacacag ataatccttt ttcatctaca tcccatgcac
    20461 cttcacattg attggccgct gtcgctccgc cccataaaaa tccttctgga aattttttca
    20521 tatcgatccc cctaaacttg ctagttttct tgtttgatta tttttcttat gactagtaat
    20581 gatatttttg aatctactac tatttgtaac aataaccatt gtggtcggat catatccctc
    20641 tttgattaat tcttgcaaat ctacttccat caataaatcg cctttacgta ctttttttcc
    20701 atcagatact gcactttgaa agtatttgcc atttaaattc actgtatcaa taccgatatg
    20761 gatcagtatc tctgctcctt cttcactgac taccccaatt gcatgtttcg ttggaaaaac
    20821 tgttgaaact tccccgttta caggactgta gatttttccg tccgttggaa tgatcgcaaa
    20881 cccttctcct aaagatccac tagcaaatgt tggatcgttt acttcagata aatcaattat
    20941 ttcacctgct gcaggagtac ttaacactat atcctttgag gattcttctt cgatttcatc
    21001 cttgtagccg aaaagaaaag ttagcataca ggaactgatc atcgctaaga aataactagc
    21061 aactagccaa acaaatcctt caccaatata aatcgggaaa gacaaaatac ttcttgtagc
    21121 aactgccaaa gcaccggctc ctgcggcacc agctactcca ccaaatatag ctccacatat
    21181 acaagcaatg taaaatggtc gtttatattt aagagtcaca ccataaacag caggttcagt
    21241 gattccaaat aatgctgtga taaatgcaga taaagataaa ctttttactt tcttattttt
    21301 cgttttcaaa aataccccaa gtactgctcc tgcttgcgca gctacggcag tcatacatgc
    21361 tggacctagc gtatcacgac cgtagaaaga aagattgttg gtcattactg gtacaagtcc
    21421 ccaatgtaac ccaaaaatca ctaacacttg ccaaaatccg ccgataacag caccagataa
    21481 aacagggcta aagttataaa cagctaaata tccagctgca atcagctgac ttgcataatc
    21541 tgcaattgga cctacaacta ataaagtaat tgggaccatc acgatgatac aaatgaatgg
    21601 tgtcaataaa tttcgaatac tttcgtgcaa gcttttgcga atcttaggct caatataaga
    21661 aagaacccat acagctaaaa ttgctggaat aaccgtactt gtatatcttg ctagaatcac
    21721 gggcatccct agaaatcgca aggttatgct atcactatat gcactgacaa tcgtaggata
    21781 aacgagagct gctgcaataa ccatagcgat gaaacgatct gtattgaact tttttgcagc
    21841 agtatatgcc aaaaatatag gcaagaaata gaaaaatgca tcagctgctg cattcaaaat
    21901 gatataagtt cctgattcag tagttaataa attcaaactc gtacataagg cgagtactcc
    21961 tttgatcaaa ccacttcctg ccaagacgcc taaagtcggg gcaaaaacag cggcgatcat
    22021 gtctataaaa gagtttaaaa tgcctttttt ctcagttcct ctctttccac tagatgcatc
    22081 atcttctagt ttcatttgtt tggataatac gtcatacact tcatttactg catttcctac
    22141 tacgacttga aacattcctc cagcttcgac tacagtgatc acaccttcta gttgctctac
    22201 cttctcctta tctgccttct tattatcttt tagggtaaag cgtaaccttg ttgcacaatg
    22261 gtaaacattg ctgacatttt cttcgcctcc gacaaatcgg acaatatctt tcgctaattg
    22321 tgaatagtcc atttttactt cccccttgtt aattaatgcc gtagcaatcc ttcttacaag
    22381 ataagtatag ttcttagaaa acggtttctc cattcaatta gtaccccttc taatagcgaa
    22441 cgaaactgta caatagtgtg tatggtttac ttagccgagc aaatcactca ctgcttgaaa
    22501 gaaaacaagt atatcgtttc tcttatagtc aaaggagaca aaaaaaacac gcttgatctt
    22561 cctttgctga tgtataagtg gtatctcaag ctgatactct gtgatttttg tttctacttg
    22621 gcttttgata agacagcaca acaaagtctc ggcatttaac ggaagcataa ctaggtcaga
    22681 actaggagag attagttgct gaatggaatc tatcttttta tggattttta tttgattttc
    22741 ttctttgtag taatgatcaa gcagttttgt tttctttttt tcttcaacta tggtcagctt
    22801 ttcacgcaaa atctgataaa tctccgaaga ttcaaactca tctagaacac taggtagata
    22861 aatcaaatca tcccactcaa aaataagctc ttgctcagta gtcaaaattg catcatattc
    22921 cgttattttg tttgattgat ttttgaaaag atacactggt tctatccggc attctttgat
    22981 ccacatgttc atactttgtt gaatctgttt ttttagtgta ttcaaaatac taattggctg
    23041 gttactaaca atcagtatct ccccttgttt tcgaaaagga ttcaacgctt cggcaagata
    23101 caaaaccaaa taagcgcttt cagctaaatt gggacgtaat tgaaaatgta ttgggaagaa
    23161 acgccgaatt aaataaattt ctaaaggata acgggagatg atcttttgta caaaatgatt
    23221 catggtatta tgtccggcat ccatcctcgt tttcatttgt ttgatatggg ttagcaaaaa
    23281 ttctgtttca tggaacaata acgaaacagg aagatctaaa aaacgaataa tcgtttgctc
    23341 aaatgctctt agattcttct ctatttcttt gtttttttca tcattaatca tcaaataatt
    23401 taactctaat agtcgatttt caattgcttg tttttcttga ttggaaaaag aatagggtag
    23461 ttctgatgat aacttttttg tgagggtctc taccatcgga ataaataatg tatacctgtt
    23521 tgttttttct aaaagttctt ctcttcgaag aatggtcaaa acgagatacc gagaaaatcg
    23581 tatgaagtcc tctcctgaaa caatataatt atatgatata agaacctctt ttaatgtctt
    23641 ttggacagtc ggcatgatat tggaaaaaat tgtactgatt tgttgaggca accttgcgtg
    23701 ttggatcacc gtttctgttc caacaagaga taagaaaatt ctttttgaat tttcttcagc
    23761 aatgattttt agtccttttg tcgacgaaac ttccagttct aatttaggat tgcgctcgat
    23821 ccaacgcaaa atcgttttta tttgtaatga tacggctgtt tttgaaagaa agaaaatgtc
    23881 tgctatcttt tgcatactga catacccttt ttgaaacaat aagtacgtca caatagttga
    23941 agctcggaaa tccatgctgg aatagatttt atgtttcgtc acctcttgta tgatttgctg
    24001 tttagtttca gattcaattg attctaaaaa ataacctgaa cgtttatttg actggataat
    24061 gattttcttc tcgtagatag caagcatatt tttgatttca gtttggatcg ttttcttgtt
    24121 ggtacctaaa gcttcagcta attcttcgct tgttatccaa tgattcttat ttcttaatac
    24181 tacaagaatt tggagttgtc gtttatttaa gtccatttgc ttacacctcc tctttgttat
    24241 aaacatacag gaaaaacctc tcaaatgaca atagtcactt gcagaggttt aaaaatcatt
    24301 tgaagaaaga tctatattca aggtttttac cattagactg gataatttgt ttataatatt
    24361 caaaactatc ttttttcaat ctcctaaagc ttccgctccc atcattttgt ctatccacat
    24421 aaataaagcc atatcgcttc ctcatttccc ctgttcctgc cgatacgata tcgattggtc
    24481 cccaccataa gtaaccaatg atttggcaac catcttttat tgcctcagca atttcctgaa
    24541 gatgtatttt tagatactca caacgttttg gatcgtggat tcgattcaat tcatctggtg
    24601 cttcatctag tccaatgcca ttttcaacta tgaataatgg taattcataa cggtctgtca
    24661 attcattcat gacataacga aaccctagag gatcaattgg ccaactccaa ggttcgggag
    24721 atttttcctt caaaaaggga ttatcgaaac catttgctcc gccagtatct acgcgcattt
    24781 ctgcttcttt tttatagaca gcgctacgat aataactaaa tgcaatataa tctaccgtgt
    24841 tagcttgcaa gtactgttcg tctccatcta acattactgg tgcacagtct tcttccttcc
    24901 atatcctgta aatataagct ggataatgcc ctcggcacat gacatcggag aaaaaccatg
    24961 aattgcgttt aaattgcagt gaaccaaata cattctctgg atcacagtca tatgcataag
    25021 tcgctaatgc agaaaagcta cacataatac ccatcttagc atttggatcg attttcttta
    25081 ataattgagt agcacgggcg ttcgctagaa acatatgatg acaggcttga taaatctctt
    25141 tttttgttag tgtagcaatg ggttcaagtt tatctctagc agggaatgta accaatccag
    25201 cagctgcata aggcatacga aaagcattat tgatctcatt aaaggtcatc caatatttca
    25261 ctttcccttg gtagcgttca aagacggtct gcgcataaaa ttcaaaaaag tcgattaatt
    25321 ttcgattttg ccacccccca tactctccta ccaatgctaa gggggtttca taatgactaa
    25381 gagtaattac tggctcgata tcatatcgat ttaatgtatt gattagtctg tcataaaata
    25441 cgagaccagc ctcatttggc ttctgttcgt ctcctcttgg aaatattcgt gcccatgaga
    25501 tgcttgttcg aaaagctttt aaacctaact ccttcagtaa acgaatatcc tcttcaaatc
    25561 gatgataaaa atcaatcgct tcatgagaaa gataatggag tgattcgtct aaagcaatct
    25621 cccaaatctt tttttcttca ttccactgaa tactaggatg ctggttcatg atcccgataa
    25681 gcgtatctgt cacattaggt aatttgccgt cttccaacca tgcaccttca cattgattag
    25741 cagctactgc tccgccccat aaaaaatttt ctggaaatat ttcctgatcc ataactatct
    25801 ctcctcgcta tcaacaattt cttacttgaa gtatagctcg attcatcaaa acaagatatt
    25861 ctaactattt cggcagaaga gaagaaaaaa attgaatgct actcttcatt tttaatattt
    25921 atatataaca aatacataag acgatccccg aaagaaaaca ctcgttaacc atctaagcaa
    25981 acgatttatt ttacttccaa cacaaatgct tcataaggtc gtaaatcaac tttgccgtct
    26041 ggtaactgtt tcagaggata atttgacaca ataaccctta aagcttcacg tggaacagtg
    26101 aacgtctgct tttcactgga catattacaa ataacgagcc attgctggtc ttcatatatg
    26161 cgagaatagg caaagacatg ctcaggcgtc ttttccacta attcatagtc tccccagacg
    26221 atgatgtcat gttttctacg caaatcgatc aatttcttgt acatataaaa aacagaatct
    26281 tgatctgcta acgcttcttc tgcattgatt tctttataat ttggattgac tcgaagccat
    26341 ggaattccag tagtaaaccc agcatgttca cgggcgttcc attgcatagg cgtcctagca
    26401 ttgtctcttc ctttcgcatt gattgattcc aagatttcct cttttgtaaa tccagaagaa
    26461 atcctttcgt tatacatatt gattgtctca atatcttttg cttccgcgat atcatcgatt
    26521 gggcaattcg tcatgcctaa ctcttctcct tgatagatat aaggggtgcc tttcatcata
    26581 tggagcaaga tagcaaacat cttggcactt tcttttcgat acacatcgtc atttccccaa
    26641 cgagaaacaa ttcgcggaag atcgtgatta ttccaaaata aactattcca tccttcatca
    26701 cctaaagatg tttgccattt ggataatact tttttcagtt cagagatact caagggtttc
    26761 aaatcccatt tgtctttgcc ttcttgctga tctaatccta tgtgttcgaa ttggaagacc
    26821 atggataatt catttctttt aggattggaa taaagtttag cgatttcggt agttgctccc
    26881 catgtttcgc caacagtcat cagatttttg tcaccaaaag ttgcttgatt catttcctga
    26941 agatactcat gcagtttagg tccattactt gtgatttctt tatccggttc tttgccaatc
    27001 atatcgatca cgtccatacg aaagccacca atacctttat cgatccagaa attcatcatt
    27061 tgataaatct cttggcgaac ctgtttattt ttccaattca aatcaggttg acgcttgcta
    27121 tacaagtgca gaaaatattg ccccgttttt tcatccaact gccaagcaga accactgaat
    27181 attgagcgca atctattagg ctcttttcca ttgaccggat cacgccaaat ataatagtcc
    27241 cgataaggat tttctttatt tttacgggcc tcaatgaacc acggatgttc atcagaagta
    27301 tgattcacca ccagatccat gatgatacgg atatttcttt tctttgcttc ttcaatcagt
    27361 tcttccattt cttccatcgt accgaattct gccatgattg cttgataatt actgatatca
    27421 tacccattgt catcattcgg agactcgtat actggagaaa gccaaattgc atcaatacct
    27481 aaatacgcca gataatccaa cctggaaata atcccccgca aatctccaat accatcttga
    27541 tttgaatctt gaaaacttct tggatagatt tgataaacaa ctgaatggtg ccaccatttt
    27601 tgttccatg
//
LOCUS       DAFEKH010000038        27251 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.039, whole genome shotgun sequence.
ACCESSION   DAFEKH010000038
VERSION     DAFEKH010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27251
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.039"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(161..445)
                     /locus_tag="LP386_001824"
     CDS             complement(161..445)
                     /locus_tag="LP386_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919059.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(463..1353)
                     /locus_tag="LP386_001825"
     CDS             complement(463..1353)
                     /locus_tag="LP386_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HBL1919060.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(1373..1591)
                     /locus_tag="LP386_001826"
     CDS             complement(1373..1591)
                     /locus_tag="LP386_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HBL1919061.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(1561..3261)
                     /locus_tag="LP386_001827"
     CDS             complement(1561..3261)
                     /locus_tag="LP386_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBL1919062.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            3528..4301
                     /locus_tag="LP386_001828"
     CDS             3528..4301
                     /locus_tag="LP386_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919063.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(4382..4951)
                     /gene="thiT"
                     /locus_tag="LP386_001829"
     CDS             complement(4382..4951)
                     /gene="thiT"
                     /locus_tag="LP386_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HBL1919064.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(5017..5119)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(5125..6096)
                     /locus_tag="LP386_001830"
     CDS             complement(5125..6096)
                     /locus_tag="LP386_001830"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBL1919065.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(6190..7563)
                     /gene="glmU"
                     /locus_tag="LP386_001831"
     CDS             complement(6190..7563)
                     /gene="glmU"
                     /locus_tag="LP386_001831"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HBL1919066.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(8066..8884)
                     /gene="purR"
                     /locus_tag="LP386_001832"
     CDS             complement(8066..8884)
                     /gene="purR"
                     /locus_tag="LP386_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HBL1919067.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(9051..9875)
                     /locus_tag="LP386_001833"
     CDS             complement(9051..9875)
                     /locus_tag="LP386_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBL1919068.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(9848..10528)
                     /locus_tag="LP386_001834"
     CDS             complement(9848..10528)
                     /locus_tag="LP386_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBL1919069.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(10551..11489)
                     /locus_tag="LP386_001835"
     CDS             complement(10551..11489)
                     /locus_tag="LP386_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HBL1919070.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(11734..12597)
                     /locus_tag="LP386_001836"
     CDS             complement(11734..12597)
                     /locus_tag="LP386_001836"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HBL1919071.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            complement(12739..15312)
                     /gene="mprF"
                     /locus_tag="LP386_001837"
     CDS             complement(12739..15312)
                     /gene="mprF"
                     /locus_tag="LP386_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBL1919072.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLP
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            15453..16259
                     /gene="proC"
                     /locus_tag="LP386_001838"
     CDS             15453..16259
                     /gene="proC"
                     /locus_tag="LP386_001838"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBL1919073.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(16338..17894)
                     /gene="rny"
                     /locus_tag="LP386_001839"
     CDS             complement(16338..17894)
                     /gene="rny"
                     /locus_tag="LP386_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HBL1919074.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQCAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(18305..19354)
                     /gene="recA"
                     /locus_tag="LP386_001840"
     CDS             complement(18305..19354)
                     /gene="recA"
                     /locus_tag="LP386_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HBL1919075.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(19463..20704)
                     /locus_tag="LP386_001841"
     CDS             complement(19463..20704)
                     /locus_tag="LP386_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HBL1919076.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(20944..21522)
                     /gene="pgsA"
                     /locus_tag="LP386_001842"
     CDS             complement(20944..21522)
                     /gene="pgsA"
                     /locus_tag="LP386_001842"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HBL1919077.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(21731..22654)
                     /locus_tag="LP386_001843"
     CDS             complement(21731..22654)
                     /locus_tag="LP386_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1919078.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(23393..24679)
                     /locus_tag="LP386_001844"
     CDS             complement(23393..24679)
                     /locus_tag="LP386_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBL1919079.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(24672..25940)
                     /locus_tag="LP386_001845"
     CDS             complement(24672..25940)
                     /locus_tag="LP386_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBL1919080.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            26192..26653
                     /gene="mscL"
                     /locus_tag="LP386_001846"
     CDS             26192..26653
                     /gene="mscL"
                     /locus_tag="LP386_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HBL1919081.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(26712..27158)
                     /locus_tag="LP386_001847"
     CDS             complement(26712..27158)
                     /locus_tag="LP386_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1919082.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
BASE COUNT         7744 a         5877 c         4726 g         8904 t
ORIGIN      
        1 taataccgag aaaatggttt ttgaacatca cttattcaaa ataaaaaaag attgtgacac
       61 gaattttgtc acaaccttta aatgtattcc tagagcaaag aagctaagcg aagaaatcca
      121 attctgatta tttattgtat ttctttgttc agcatccttg ctaaaagccc atattggaca
      181 aagtattcac tacacccatg atctcatctt ttcgagaacg tgctttttct gtcggatctt
      241 ctacctcttc tgtgtcaatt cgaacaataa atttccgatt catcgtcacg taagcaccgt
      301 cgttgatcaa aataaacagt tcgttctcat tatagtctgc acaggcatct ttccatacgt
      361 caaagccgtt tttttcagaa gggatatccc gtttaaccac agtttttcca cttaattcgt
      421 ggaacgttac gtcataatat ttcattatct ctacctcttt cgtcattcaa tattttgtac
      481 ttgttctctg attttttcta agatcgtctt agactggacg acttgatttt taatttcgat
      541 tgcatttgat ttggaaccga tcgtgttgat ttcccgattc atttcttgga tcaggaaatc
      601 taattcccga cctacaggac attgtgcttc gataagttca tctagttttt gtacatggat
      661 cgccagacga tccagttcct cgtgaatatc tccgcgttcc aacaagatgg ctagctccgt
      721 caacaaccgt tgctcatcga ctttcgctcc aagaaattcc tccagctttt tttgatacct
      781 tatttgaaat tccttttcat agatttctac aaaactatcg agttttttta gtacttcttt
      841 gaattcttca gtattctttt tcaacactaa agctaaagct tgaccttctt tttctcgact
      901 cgcctcaata gaatcaagtg cgcttttcaa tgtatctaga gctaactgtg ccaattcttc
      961 catgctctct tccggttttt cttctaccgt tacgaagttt tcgtccagcg cgaagcgttc
     1021 cgccatccga ctaattgaca cttgattttg actaccgtat cgttgttgaa ttccgtctgt
     1081 caattgagtg ataagtgaat caatcaattc ccagttgatg acgatctgtt tttcgttttt
     1141 gccaatataa gctagattca caaatacttc gattcgaccg cggcttaact gctgtttaat
     1201 aagctgacga aaatcgtttt caacaaagtt caggatttta ggacttcgta tttgaacatc
     1261 tagaaaacgc tggttgacac tttttatttc aatatctaac tgatacgctt ttgtttcgcg
     1321 gatggctttg ccaaaaccag tcatactttt cattcgacag ggtccttcct cattacatat
     1381 tttctattgc tttttgcagt tgttcaaact cttcgttcgt caatgtcagg cctttcccca
     1441 ttttttcatg gtctggcgcc caatctcgaa gatcgaattt tggcgggcga ccattccagc
     1501 tgactaggtt cagttcttta cgccacccct tgttgttttc tgacaatata gcgatttctt
     1561 ctacgatttc atatgaaaat tcttgtgcca tggttgttcc tccttgagat aatataaata
     1621 taggatcagt aatgtgtcaa ctggttgctt aagcaattca tgctgcaaac gatccttgcg
     1681 ttttccttgt agcagataat caaaataaac agttttcgtg cgctcatttt gtattttttg
     1741 ctggtatttt cgataccttc gccattcttc agtacttaat tgaccaattt gtgccaataa
     1801 atcatccggc atacttttta tatcttgttg gcagatcatt tgaatcatca tgtctacttg
     1861 atagatttca ttgggcagta aaaaatgttt ttttgctaaa agttctagca tcgccaatcc
     1921 gcatgtctct ggtacgaccc tgttcttata taaattacgc agtttttgcc aaaattttat
     1981 gcttttgaaa aaagataatt ctaactgaat ttcttttgtt aagtaagaca aaaatcctcg
     2041 ccagtatgtt cttgcaggtt taacagaatg aaatgtatac cagttcccat agtaatagcc
     2101 taatcgtttt ttcatttcca gatagcctaa ttgtaaattt aattggttcc tttggctatc
     2161 aaaaagcaga aagctgccta gtgtccacaa tgtttgacat ttccaatgga taaaaatgtc
     2221 tggcatacga atttttttcg ctgggcctgg cccttgcaca tctacgacaa atgcctctgt
     2281 tgctcctttg ttaatcgcaa tatcaatagg tattttgttg cgatacccac cgtctgcata
     2341 tttatttttt ccgatctttc gataagccat agcgggataa aatgaagcag aggcgagtat
     2401 ccaatctggt atttcttctg tttttgtctg ttggatatca gtcactactt ccgctagttc
     2461 tggcagttta gtagacaccg tatataaacg tattttggga ttatgtttga gtaaggacaa
     2521 atccaaattg tctttgacca tcttttccaa tggagcagaa gaaaccccgc cttcaattag
     2581 tgctgttttc gtcatttggc gtctttctcg atagaagcgt tcacgaaggt cttcaactgc
     2641 agccatttct ggtaacgcaa gcacttgtct tgtcgacagc tttttccata aattcacagc
     2701 ttttttcata tctccttgta aaatcaatgc gccgttcaac gcacctaccg aggtacctgt
     2761 gataatctca aagttgatat catgttcctt cagcgcctgc cacacaccaa tctgataagc
     2821 accgtgcgct cctcctccac ctaaaacaag tgctgtatga tagaccagct ttttatttaa
     2881 ttgtgtggtt ccttgatagc cgtttttatg aaaaatacgc aaccattctt ctgatagagg
     2941 agattgaaat aaaaaacaac agttttcttt aataaaaaaa cgagcgcaag cttccatata
     3001 ccgaaaaaat tttttccatt caaaagtttc accttcaatc aacagattat taaaaataac
     3061 atctcctcta cttttagcaa tagtaaaata gacggtatat tttttcgata ctgctttaaa
     3121 agcacattgc ttttttgcag aacgccaaaa agcgtctcta ctttcttgat gactttgaaa
     3181 aaatggaagg ggttgttttg cttgctggat aggcgaatac agcgacattt tctgtgaaaa
     3241 gtaaactttt tttatctcca tcgcgctctc ctttttcttc aagtatacca gtacgtcata
     3301 aaaaggtcat gagtctcgta ttcgactttg tagattccat aagaaaacaa ttcataaaac
     3361 ctcctttaaa taaaaaaata caaaaatcac aaaaattaat tgaaaatgag agtgttttca
     3421 atgaaaacgt gattttgtaa tggaatttta aaataaaaga aacaagcttt tttaatgcaa
     3481 atgttgtaaa ataaaagaga ttaagaggaa ataagaggag gaacatgatg actgagtcag
     3541 tttatgtaca tattgatacc acaagtaatg ctgttttaac aaaagggctg actgctactg
     3601 actttgcaaa cagtatcgtg cattttcctc aaaacttgct cttgcttgat ccatctgctt
     3661 ctgctggaga atatgaatcc catacagggc tgaaagtaat ccgtggtaca gaaaatattc
     3721 agcgtttctt ttcctcttct cgtaacaggc gtggattcga tgaattgaag tggatcgact
     3781 ttactgattt aacgatgctg aaagaattga cacctttaga aatttcagaa ttattatatt
     3841 ttggtcatat gaaaacacat cttcattcgc cgttttttta taaactacag aataattttg
     3901 tatacttcga tcttaatgat cagctgaatc ggatttatta tcgctattta gatgaatttt
     3961 ataggatttt tgctagtaaa ttaagttcga tcttgtcaga taagatcaat gtaaaaaaat
     4021 cttttttcaa aaaagaaaca cctgttgaaa aaatcagtgt ggaattattg aaagaaatgc
     4081 gtaatttgat gcaggaaggg atcatttttt cttttgatca agttggtttg atcgatggta
     4141 aatatcgtat cccaatctat gtgattgaag attatatttg gaaattaaaa ggcacccggt
     4201 atcgagaaga ggaaatcatc gctactttaa tctactctgt caccgatcga cactggcaat
     4261 tggtagaaga tgccgatctt tcttatctgc cattgaagta gatctatttc ttatcaaaaa
     4321 ataaaaagga aacaagaaac taggacatga ttctgtctca agtttcttgc ttctttttta
     4381 tttacagctc ctgtcgttta tctggcacaa aaatcgaagg agtcgtttgt tggatcccta
     4441 ataaaacgat gatcgttaca atagctgtac tcaacccgct ggcaccattc attacgaaag
     4501 aaaagagcca aggattcatc ccccatagtg catacgctcc ccagaaaacc actcctgcaa
     4561 taaaatgcca aaaatatctg gaaagtgcgc caatcaatgc accaaacacg atgctttttc
     4621 taatttgttt cgtattatcg tctacatagc ctttttggac atttgaagcc atgagccctg
     4681 ctgcgcctgc aaaagtatag gcaatcgggt actcaatcaa cacttgaacg acacttaaat
     4741 aataaacttg tcccaacgga aaatgtagga tgccccaaat gaaacctgcc agcatccctg
     4801 cctttgtccc tcttcttaac gcaaaaagag tcaatggaat ctgccctaat gaaatagaaa
     4861 aactgctgcc gatctggatc ggaatcaacg acaacaccat cgctaacgct gcaacaatcg
     4921 ttccttctac ccaaactcta ttttttccca taaaaaaact tcctcctttg aataaaaaag
     4981 tcacaaagga ggaagcagct ttcgaaaata gtcaaacagc tgtttattca caattcctac
     5041 gctcgcataa ccgatacagg tacgaagggt ttagaaatag attcaatctc agcccaattg
     5101 gactcccctt tgtgagttta tttattattt attttttgtt tcaaacaatg gactaactgg
     5161 tttgttttca tggatacgtt tgattgcatc tcccattagt ccgccaacac ttacttcatc
     5221 gattttgtcg attttacgat cttctggaag atagatcgag tctgtaacaa ctagacgctc
     5281 gatagctgaa tcttctattc tttgtaaagc agggccggat aatactggat gtgtacatga
     5341 agcatacaca ctagttgcac cagcttcttt caaagcattg gcagccaatg tgatcgtacc
     5401 tgctgtatcg atcatatcat cgatcagtac acaagttttg cctttgactt gtccaatgat
     5461 attcattact tctgcaacat ttgcttttgg acggcgtttg tctatgatcg caatcggaga
     5521 tttcaaaaat tccgctaatt tacgtgcccg tgtgacacca ccatggtctg gtgaaacaac
     5581 gacaacatca tcgcctttga ttcctttttc taagaaataa ttggcaataa gtggcgcacc
     5641 catcaaatga tcgactggaa tatcaaagaa accttggatt tgaactgcat gaaggtccaa
     5701 agtcagcatt cttgttgcac cagctttttg aatcatgttt gctactaatt tcgctgtgat
     5761 tggttcccgt gcacgtgctt tacggtcttg acgcgcatag ccataataag gcatgactac
     5821 gttgattgtt tttgcacttg ctcgtttcag tgcgtcaatc atgatcagca actccatcaa
     5881 gttatcattg actgggctgc tcgttgattg aataacatag acatgcgatc cacgaatact
     5941 ttcttcaatg tttacttgaa tttctccatc actaaattga gtaacagatg attttcctaa
     6001 ctcgacgccg actgctgctg caattttctc tgctaatggg cgattggaat ttaacgcaaa
     6061 aatttttaat cttgggtcaa agtaatgttt tgacatgggg acctccactt tctttttcac
     6121 aactctagaa ttctacctaa taaatagtag tcatattttt taaataaatc aagtgatttt
     6181 gcaaaagtct tagtttagat aagggagttt ttttgcatat ccttctttat tgacttgtct
     6241 tgctctcgca attgccagcg catattctgg aatattgtct gtaattgttg acccggcagc
     6301 aatcgaactg tttttagcta cctcgacagg tccgatgata ttcgtgctag aaccaataaa
     6361 gctgtggtcg ccgacagtcg tatgatgttt gttctttcca tcatagttga cgaagacaac
     6421 accacatccg acattgattt cttctcccag cgtagcatca ccaacataag tcaagtgacc
     6481 gactttagtt cctttgccga tttgagcatt tttcacttcc acaaagtttc cgatatggac
     6541 gttttcgcca atttcagctt ttggtcgtaa atgtgcataa ggtcccacat ctgcatgttt
     6601 cttgacatgg ctgctttcaa tgactgagtt ttcaatgacg acgtgatcct caatcctact
     6661 gtctacgatt tttgaatgtg acccgatgac acaatcagaa ccaatgactg tatttccttg
     6721 gatttgtaca cctgcttcga tcaatgtgtc tggaccgatt tctacgcctg catcgatgta
     6781 tgtcgttgct gaatcgacaa agcttacgcc attgaccata tgcatctggt taattcgctt
     6841 tctcatgatc tcatttgctt tagctaacgc gatccgatca ttgactccca ttgattcttc
     6901 aaaatcatcc gtttgataag cagcaactgt atggccttct tcttttaaga tttcgatgat
     6961 atctgttaga tagtattcac cttgagcatt gtttgttcca actttgctta acgcatcgaa
     7021 caaagcttcg ttgtcaaaac agtaagttcc tgtattgatt tcttgtacaa gagcttcttc
     7081 tggtgttgca tctttttgtt ccacgatttt ttctacgatc ccaatatggt cacggatgat
     7141 tcgtccatat cctgttgggt tttctgcttg tgccgtcaag atcgttgcac ttgcattttt
     7201 tccttggtga tattcaaaaa gattgttcag cgtttcagta gtcaataatg gtgtatcgcc
     7261 actgataact aacgttgttc ctttttttcc ttccaagaaa gaagcagctt gcaaaacagc
     7321 atgtcctgtt cccaattgtt ctgcttgtaa cgcatattta ctgcgttctc ctagttgtgc
     7381 tttaacttgt tctgctccgt gtccaacgat cgtaatcact tcatctggtt tcgtttcact
     7441 gacccgatta atgatatgtt ctaccatagg tttaccagaa acgggatgta aaactttata
     7501 taattttgac ttcatgcggg tacctttccc tgccgccaaa ataattgcat aacgtgcgtc
     7561 caactgcgtc actcctaaat atagtttgct gatttcagtt tatcccagta tacccatttt
     7621 ttcaacaaaa caagtgattt tcttttatcc cagcgttttc tggataaaaa aatagataga
     7681 ccataacggg cctatctatt tggtaaccgg tgctctcctg ccaactcctc ggtcacaagt
     7741 cacactactc ataaaacatg aaaagctgtt ttttgaaatc gtttcttgtg acttagagtt
     7801 aaacggtagg cttacaacct cttcattaaa cgtttttcaa tcagctgacc ttcggtatta
     7861 gctcaataaa cggcaaaata tgaggagcaa tttttccgtt tattgagcta atactcagga
     7921 caggacgctg atttcacaac ctctagataa acggtgttca aaagccagtt tctcggtatt
     7981 aagccaaatt tatgaaaaaa tgtggaaagc cattttcaca aaatttttct tactactcga
     8041 aactaagcag ctttttcaca acctcttatt ctgaaaaata atttcctggc acaaccgtaa
     8101 tatttttcgt ttgagtatct acatctttga cataaagcag tgacgtataa tcatcgatgg
     8161 cgcgatgacc gttgaatttt gattcggcaa atacagtgat gccaacaagt tctgattcga
     8221 attcttcaat caagctcttc attccgttga ctgttccgcc gcctttcatg aaatcatcca
     8281 ctacaaggac acgtgaacca cgtttcaaac ttctcttaga cagttccatc ttttcaattc
     8341 tttcagaaga tccagacaca tagttgacac ttactgttga tccttctgtt atttttgagt
     8401 cccggcgtac aataacgaat ggcgcattca gataatagga cacagcttgg gcaataggta
     8461 cgccttttgt ggctacagtc attacagcat cgattttttc accaaggtat ttagaagcaa
     8521 tgattcttcc aacttgacgc agcagttcag gttctcctaa caaatcagag agataaacat
     8581 atcctcctgg aagcagacgg tcttgttctg atagacgttc tgctagagat tcaatatatt
     8641 ttttcgcctc ttcatatgaa atttcaggga tgaacaatac accacctgca gcacccggga
     8701 ttgtttccaa ggttccatac cctcgttctt taaatgtttt cttgatgatt cccaaatctt
     8761 cactgataga agatttagca gattcataac gttcggcaaa gcttgttaag gaaatcaatt
     8821 catgcgggtg attcaataaa tactgtgtca tgtcaactag acgttcactg cgacgtactt
     8881 tcacctattc caactccttt taagaaattt tatcgtttta cattatataa gtttttcttc
     8941 aaaaattcga gcattttatg aaaaaataag aaaatagttc ggtatttatt aaaataaaaa
     9001 gaagcctata aaaaattttt cgtttttata aggcttcttt tctttataat ttagttattt
     9061 tttcttctga aggcaaccaa tattcgtttg atgatattta caatcaggaa caaagcaata
     9121 aagactaatg tgattgttgc tcctggaggt gtatctagat aaaacgagct agttagtcct
     9181 gacagcatcc ctagaaatcc tacacaaaca ctgatagcaa tcacgacatt gaagcttttg
     9241 cctaatcgca taccgattgc tgcgggaaga accatgattg cggatatcaa aagtgcaccg
     9301 gcaatcggga tcatcacagc aatagccaca ccagtaatca cattgaacat catcgacatc
     9361 aaatgaacgg gtagcccatc cacgtgggcg gtatcttcat caaaagtcag aacatacatc
     9421 ggccgtttga ataaaaagaa caatataccg atggcaacga ataagattcc taaaaagatg
     9481 acttgctccc atgtaatggt cacgatcgaa ccaaacagat aggattggat acttgttgct
     9541 gaattccctc cgctcaaatt catcaatact aacgctagcg ccaaaccacc agccattaaa
     9601 atggcaatgg agatttctga ataggttcgg tagatcgttc gcagatactc caatatcaca
     9661 gctgctaata caacgactag catggtcgta agtgtaggat taaggttcaa aaagaatcct
     9721 aacgctaccc ctgctaaaga gacatgagaa agcgtatcag ccatcagcga ttgtcttctg
     9781 atcactaaaa acacacctag catcggggcg attccggcaa tgaagatagc ggcaagaaac
     9841 gctcttctca tgaattcata tgaaagcaac gccattgaga atcctccttt ctcaccagtc
     9901 ggatctgtct gtccgcatac tgtttgatat cttcatgatc atgggtgatc attagaactg
     9961 atttcccatg gacatgcgca ctatgtcgga gaagacgata aaattcattt ctggattctt
    10021 catccatacc tgttgttggt tcatcaagaa caaataagtc agggtcagta gcaaaaatac
    10081 gcgctaaact gattcgctgc ttttgtccgc cagacaattc acctattcgc cgatttcgca
    10141 tatcccacat ccctacagct tctaaagcac gctgtacatg ttgatgatct ttttcagaga
    10201 gacgcttgaa ccagcggcct cttggatatc ttcctgaacg gactaattcg atcaccgtac
    10261 taggaaaacc tgcattgaaa gatgcaactt gttgaggaat ataaccgata cttaattttt
    10321 ttccttcttg atttttctca gcaatcttta tcattccttt tgaaggtttc agtaatccta
    10381 acgatgcttt caccaaggtt gacttggctg ctccattttc tccagttaaa atgacaaatt
    10441 cacccgcatc tacatgataa gagacatctt ctagtacagg ttcatcatca tagtaaaagg
    10501 tcaaatcaga tatttcgata taacgcacct tacaacctcc attctaaaac ttaattgata
    10561 ctttctttta aagctttcag atttttttcc atgacagaaa tataattttc gcctgctttg
    10621 atttgttcat tagtcaagct ttctaaagga ttcaacactt ctagcttcac tcctgtttca
    10681 ttcgacaatg tctcagctac cttcgaagag gcattttctt caaaataaat cactttgatg
    10741 ttgtttttct tcacaaattc ttttagctca gctaagcgac ttggtgtggg ttcctgatct
    10801 ggtgaaacgc ccgaaatcgc tacttgtttt aagtcgtatt gattcgctaa ataagcaaaa
    10861 gcagcatgct gagtgacaaa tgtgcggttt gttgcatctt ttagctcatc ggagtatttt
    10921 tgatccagtg cttcaagctt tttgatataa gcatcggcat tcttcgtaaa agtttccttt
    10981 ttatctggat atttttcgcc taattcttca gcaatcgttc tgacttcttt tatagctaat
    11041 accggatcga gccaaacatg tggatcgtat tcatgtgaat gaccatgccc ttcttctgat
    11101 tcttcatgtt cgtctgcttc ttgcgattct aaacggtcga ttcctttagc tgcttcgatc
    11161 atcaaggtct gtttgctatc cactgaatcc tttaacgaat ccacaaaaaa ttccatgtct
    11221 gaactattat acacgaaaac atctgcatcg gaaatttctg ctctttcttt tgcacttggt
    11281 tcgaaatcat gcggctccgt tccagcaggg atcaaaagtt tcacgtttcc ttcatcccct
    11341 acgatctctt ttgtaaaatc atacatcgga taaaaagtcg taacgatcgt caaatcctct
    11401 tttttgtctg cttccttgtt cgtatttcca catgctgcaa acagtaaagc acctatcatt
    11461 accgtagctg tcaaaagata ttttttcatt tatatgctcc tttcaatgaa caaatcggaa
    11521 ttttacgatt tattaacgtg aactaatgta tcaaaataaa aaaacacagt caatagaaat
    11581 ccatcaattt ctgatttaag catgtatatt cttgattaaa tcgtaaaatg gatgagttgc
    11641 tgctcatatc tagccatttc actacaataa aaaactgaag aataccattt taggattcct
    11701 cagtttttca tcacctattt tacttcttat attttattgc agggttcgta ctaaataaac
    11761 ttcctcacaa aaacctttta acccattata tactctctgc gctcttgaat aatgttgaca
    11821 caaggcaaaa acggttggtc cgcttccact catcaatgca gcatctgctc cgtacttgat
    11881 catacgctct ttgatttgat ggatgactgg atgccgcttt cccgttatat cttctaaact
    11941 gtttcccatt tttttgatca tctgctgata atcttgctct cggatggctt cagcaagtcc
    12001 gtggatgtct tgatgttgga tggcttgcgt atctacttct ctaaacactg tacgtgtaga
    12061 gacactcatt cttggtttga ccaacacaac ccagcactgt ggcatagaag gtaatacttg
    12121 gatttcttcc cctttgccac cgacaaatgc cgtacttccg tagacacagt aaggaacatc
    12181 tgtaccgact tccaaaccga tttctgccag ttcttctaac gaacagccca gattccataa
    12241 ttggttgatc cctcttagag cagctgcaca gtctgtactt cctccgccta atccagctgc
    12301 tactggaata ttcttcttaa caaagatctt gacaccggtt ttgatattgt atttattttt
    12361 tagcaataaa gcagcttgat aaacattgtt ccgttcatct accggtaaaa atgctttatt
    12421 tgtttctaca atgattttgt cttctgttat ttcttcaaaa aatagatgat ctgccaagtc
    12481 tacgctcgac atcaccattt ccaactcatg atacccatct tgccgtctat ataatacatc
    12541 cagtcctaaa tttatcttgg ctggcgcttt ttcaatcaat tccatcctct cacccattcg
    12601 aaaagtctaa gtcgcaagta ttctatcata gggaaaaata aaagtatagc ttatgtctgc
    12661 ctagtggttg attttgtcat cgtttcaaca gctttcacag aattttctct tcataatcca
    12721 aacaagttct agtgattctt ataattctgt gagcacttct tctgccaaac tcggaacatt
    12781 tcctttttct tttcctatca gactgagtag ctgcatggta gcaaatccga aattacttcc
    12841 tttcctataa gcaaaataac gtccttccca atgatcgaca tattttaatt tcttttcata
    12901 agcagactgg aaggaataga aaaaattacc ataattatat acgatatgca tgactttttc
    12961 ttgaaagaaa gaaaaatctg tttctccaac attagctaat ggagctaagc ctagattggc
    13021 ttccgagtag cccattttct cgtatacaat aaacagattg gctaacagat agtcagctaa
    13081 ttcctcagat tctttaggta agacccgcaa caaatcatat cccgcctgct tcttcgtcat
    13141 cggctgagcg gtgatgaagc caacgacttt ttgatcttta cggacaatac cgacaccgct
    13201 agataataca tatgatttat caaatcgtcc cacagagaag tatttttctc gtgcaccttg
    13261 aagccatttt tgtgaaactt catttacagc ttgatgtaat tcttccggca gttgatcgta
    13321 ccaagtaaaa tggtatcctt ctttcatcaa acgttgatat tcaagttgct gactcagccg
    13381 agacaagtct tctgttgcta gatcaacaat ccctgcttca cctactttcg tgaagtgaaa
    13441 acccaattca tgaagcatca ctacgtagct ttctgatatc ttataaaacg caagctgata
    13501 gcctaaacaa tctgcttgtt tcataaactg attcgttgct gcccgcatca ttttaggatt
    13561 gccaactgga tctcctaaaa caaagcattt gtttcctttg atctgataac caaaaacgac
    13621 ttgatcttgg tcgtcttctt ggtaataaaa ataactgtaa cctgacaagc gaagctgatg
    13681 gcttgtagct gtgcctccgt atgtttccaa taaacggtca aaacggtctt tttcgtactc
    13741 actgccaagc ttcgtagtat cttcagctaa atattgataa agcgccacta aagctagcaa
    13801 tgagatgccc aaaccaataa gccctgagaa ccacacatca tctgaaggaa acaaaataaa
    13861 atgatttcct gttattcgac cgactaaaaa gcgtccgctg tgatagcctg caattgcgta
    13921 aacgataaac aaaaagccga acaagctagc atcaaagatt atagctcccc aagaataaac
    13981 gaattttgtt cgataaaatt cttttctgga taaccacaca gctaacagaa tcaagacata
    14041 taccaatatc aactgccaag ataacgtacg tgtgattgta tttaaaatac caaaagatag
    14101 taaagcaatc gtaggcagaa atgccttttt gacttttact gaaagtgctc tagcaaggcc
    14161 gagtaataaa aagccaacca atagattcac tgtctgatct aaaaaattga atgagaacgg
    14221 caataatact tgaaatagcc gactgattgc agacagatta gtgattgttg atagaagtac
    14281 catcatgatc cccgcaaaat agacagcact tacgagcacg atatgcgcaa ccttttggaa
    14341 aaacagtcgc ggaatgttat ctaaaaatcg attgattttg actcctgtat gtgtgatgaa
    14401 caatagaagt cccgtcataa aaggtagaac ataataaaac aaccgataat ataatagcca
    14461 aactactgct acatcttgcc gaacaggcaa ttgactcatt cctaagatca tcaaaacgtc
    14521 aaaagtcccc attccacctg ggaccatcgt cagcattcct atcaatgtag caatcatgaa
    14581 cataggatag atcgaaagca tcgaaatatc tattctcatc aacttgccga tgatcaaaaa
    14641 taccgcaagg gctcccgtcc attgtccaaa ggatgccagt agcagaccaa gcaagccttt
    14701 tggataaaac tcgaagaaca atgtctttct ctttagataa gcaaaaaaga aaatgactgg
    14761 tgctaaaaaa ctaccgccga aaagccagat ccaatagctt cgaaaaatac tttctgactg
    14821 aataaaaaag acatcaataa atgtaagaaa cgaccataca gacaaaccag tcagcataaa
    14881 tagtgcgact tttgatacag tggctaaaac catttttcta tttgtctgct ttccataaaa
    14941 actagcccgc agacttgctc ctaccacacc accaaaaccg gcgagattgt tgatcgtgtt
    15001 tgttacccac gcagcaagaa gaaactcttt tctttccatt tttggttttc cttgtttttc
    15061 taagactctg atcgtcaccc aatcatacaa caacatcgga gtgacaccca gcagtccagc
    15121 cagaatcatg agcaggatcg tcatgcggct ttgttgtccc atcctttgcc aaatatcttg
    15181 ccaactcatg ccattagcaa tatttgcgac ttgatttgcc acaaagacta acacggagcc
    15241 gaaaaaaatc agttttaaaa tcagactatg ttcctttatc cattgcagca tcaagtatcg
    15301 tttatttttc acattttccc attcctaact tgtatacttt tgtgtcatac cccaatgtta
    15361 tcttatttat tttaattttt ccactttaga cctgttcttt gcttgcgatg atagaaaaag
    15421 aaagatatcc taatgctaaa ggagaggata acatgaaagt aggatttatc ggcacaggga
    15481 atatggcaca agctattatt gatggtttat taaaaaaagg aacagtctcg aaagaagagg
    15541 tgttcgtttc cagtggacat tttgaaaatg cacaaaaatt tgctgctgaa actggcgtcc
    15601 atgcatgcaa aagtaatcag gaagttgcat cacaatcaga tatcgttctt ttagccgtga
    15661 aaccaaaaat cattgaaaaa gtattggaag aactaagaga atatagccag aaagtcttat
    15721 tcatttctat tgcttcagga aaatcattaa cagatttaga aacagcgctt gaagatcctc
    15781 aggcctccat cgtacgtgtg atgccgaatg tcaatgtcag cgtaggagca ggcgtttctg
    15841 cgatttgcaa aaatgaagct gccacggagg aacagcttca gcaagctacg atgatttttg
    15901 aagcaatcgg cagcgtctat cctttagcag aatcagattt cagtacattc attggccttg
    15961 ctggcagctc acccgcattc gtttacatgc tgatcgatgc gatgggacgg actggtgtac
    16021 tgaatggttt gtccaaacag acagccactg agattgctgc aaaagcaatt atgggttctt
    16081 gtcaaaaatt cctttcaagt gataaaaatc catgggaact tgtagaccaa gtttcttctc
    16141 ctggcggtac aactgttgca ggtgtagttg ccttagaaga agcaggattc atcccagcaa
    16201 tcatcaaagg aatcaatacg acgatcgaga aagatcttga gatgttgaat aaaaaataat
    16261 gatagcaatg ttttttcgtg ccttacaaaa aaagaagagc tgtggctttt gccgcggctc
    16321 ttcttttgta ttttttatta tttagcataa tcagttgcac gagtttcccg aataacgatt
    16381 actttgatgt gtccaggata atccagttct tcttcgattc gtttacgaat atcacgtact
    16441 aaacgaacag cgtctaaatc cgagatttct tctggcttga ccattacccg aacttcgcgt
    16501 ccagcttgaa ctgcgtaact tgattctaca ccggcgaagc tgttcgaaat attttccaga
    16561 cttcttaaac gacggatgta gttttctaat gattcacttc gcgcaccagg tcttgctgct
    16621 gagagcgcat ctgctgcagc tacaaggaca gagataacag aagtagcttc cacatctcca
    16681 tgatgagaag cgatcgcgtt gattactact gggttttctt tgtacttggc agctaattcc
    16741 gcaccgatct caacgtgaga tccttcaatc tcatggtcaa gtgctttccc aatatcatgg
    16801 agcaacccgg cacgttttgc taattggata tcttcgccaa gctctgctgc taagatacca
    16861 gctaattttg caacctcgac cgaatgcttc aagacgtttt gtccataact agttctgaat
    16921 cgcagacgtc cgatgatctt gattagatct ggatgaagtg tatgagcacc gacttcaaac
    16981 gctgcctctt ccccgtattc gcgaatacgt tcatccattt ctttacgaga tttctcgacc
    17041 atttcttcga tacgcgctgg atggattcgt ccatcttgta tcagtttttc caaggtcatc
    17101 cgtgcgattt ctcttcggat tggatcgaat ccggaaagaa caactgcttc cggtgtatca
    17161 tcgatgatta aatcgatacc agtcagcgtc tcaagcgttc gaatattacg accttctcgt
    17221 ccaatgatac gacctttcat ttcatcattc ggaagggtaa cgactgaaac agtcgtttct
    17281 gaaacttgat ctgctgcgca gcgttgaatc gctaatgata ataagttttt cgctttgcga
    17341 tctgcttctt ctttggcaca ctgttcagat tcttttacca ttagagttaa ctcatgattc
    17401 agctcttctt cagtcgattt catgatgaca tctcgtgcgt cctcttttga taaaccagca
    17461 attttttcta gttctttttg ttgatcttca atcatttttt caacgtcttt ttctcgctct
    17521 tcaattaatt gctgttttga actaagtgct tcttctttac tttcaagtga gttctcgcgt
    17581 ttttctaacg agtcatcttt acgattcagc gtttgttcgc gttgaatcaa acgattctct
    17641 tgagatttta attctaactt actttctctc agctcacttt caacttcaga acggtatttc
    17701 tgattttctt ccttagcttc taacaatgct tcttttttta gagtttctgc ttcttttttt
    17761 gcactatcga tgattccagc agctgatgat tgtgcaccag ctatttcttt ctcgtgacgt
    17821 gactttgcga ccataaaccc taaaccaaga ccgacaatta aaccgatgat agcgaggaga
    17881 atgttgaata ccataaaatc cacctccata ctatcttttt catttttatc atctatacag
    17941 cttctatgat aaattattct aaactcgtca atatgcatct tcgcatatat gtgtacaaaa
    18001 aacatgcaca actttattct aatgtttgta ccccgtagtg tcaactttaa ataaacaaag
    18061 aaacggcttt ctacttattc attaaacgat ggtttttaaa ataaatgaca ctagtttcat
    18121 ataggtaaac ctttaaattg agaaactttt ctattaaatt attctttgta gatgaacaga
    18181 tatttttatt ttatgtaccc actcgtataa ttaaataact cacgatttct ttattcaata
    18241 aaaaaacggc aggtcaagga gagtacctac tcttcagacc agccgttttt gtttatcata
    18301 atttttattc ttctactaaa ggcaattctt cttgtccttt ttcatcttct gggacagcga
    18361 cttcttcacc aataccataa gctgctctaa ctagagcaga aacttctgcc atcatttcag
    18421 gatgattagc catatagatt ttagcgtttt cccgtccttg accaatccga tcttctttat
    18481 aagaatacca agcaccgctt ttatcaacaa tgtctttttc tactgccatg tctagaagtt
    18541 ctccttcttg tgagatccct aaaccataca tgacatctac ttcagcgatt ttgaaaggag
    18601 gtgctacttt gttttttacg actttgatct ttgtacggtt accaacaata tctgtacctt
    18661 gtttcaattg ttctgcacga cgtacttcca aacggatcgt tgcgtagaat ttcaatgcgc
    18721 gtcctccagg agtgatttct ggattcccaa acatcacgcc tactttttca cggatttggt
    18781 tgatgaaaat agcgattgtt tttgttttgt tgatcgaacc agagagttta cgcaatgctt
    18841 gagacatcaa acgtgcttgt aacccgacat gtgagtcacc catttcgccg tcgatttctg
    18901 ctcgtggaac taaagcagca actgaatcga ctactacgat atctacagcc ccacttgata
    18961 ctaaagcatc agcgatctct agaccttgtt ctcctgtgtc aggctgtgaa agaagtagtt
    19021 catcgatatt cacacctaat ttttgtgcat attgcggatc taacgcatgc tcagcatcaa
    19081 tgaaagcggc cgttccgcca tttttttgta cttctgcaat agcgtgtagt gcaactgttg
    19141 ttttacctga actttcaggt ccatatactt cgatgatacg tccacggggg taaccgccga
    19201 cacctaaagc gacatctaac gcaagagagc cacttggaat tgtagagatt tgttggtcga
    19261 ttttttcgcc caatttcata atagagcctt taccatagct cttttcaatt tttttcagtg
    19321 cagcatctaa ggctgcttta cgatcatctg ccaatacgat aatcctcctt atatttacaa
    19381 atcagagcaa catttcatta tccttatcat atctttttta gtgaaaaaaa gcaagaaaaa
    19441 accgaacaaa tattcgcatt tatcattttc ttaaaagctg ttttctcaaa agatcaaatc
    19501 cttgcataac cgcattatat ctgatagcag cacgatctct ggcaaagtga tatttttccg
    19561 aaaccacgcc gtctttagat gaaatagcga tccatactgt tcctgcagat tgaccttcta
    19621 acgtgtccgg tccagccact ccggtgaaag ctacactgta atctgttctt gctatctcac
    19681 gtgcttgaat ggccatctgc tccacacatt ctttgctgac tgttccatat tctgctaata
    19741 gctccggatc aatctccaga aaaccagctt ttgtttggag cgagtaggta acgaatccgc
    19801 ctggaaatac ttcagataca ccagcaatgt cgcctaatgc ggcttggaag gcgccggctg
    19861 tcaaactttc cgctgctgtt acagtctgct tgttttcttt cagtagttcc actacgactt
    19921 ttgctagcga attatcatcg ccgtatccat aaaaatattc ccctactcgt tcttggattt
    19981 tttcttctaa tgctaaaaga gcttgattcc ctgcctgaac atcatttgtt ttcactgtca
    20041 gtcgtaatgt cacttcattt ggtttggcat atggtgcgat cgttggattg atctgtgtct
    20101 caatcagatc ttttagctca gtgaccagtc gcgattcacc aatcccataa aagcgcaaaa
    20161 ctttagaaat tagtttttct tcagaaggaa aacgttcctc tagtaaagga cgtacttgtt
    20221 ccacaaacat tggtttcaac tcattaggcg gaccgggaag aaggatatac gcatgtgtat
    20281 ctgtttgata aaaagtccct aaagcaagcc ctgtacgatt tggtagagga accccgcctt
    20341 cgataatctg ggactgttgc agattgtttt tggtcatttt tcgatgggtt gtttcaaaat
    20401 atgccaataa ttttttgtat ccttccgtat tttgtatgag agacttaccg aggtgagccg
    20461 cagttgcttc ttttgtcagg tcatcttctg tcggtcctaa tccgccacat aagagtatga
    20521 gttcacttct tgtttcagct agagcaatca actcttctaa acgctgctga ttatctccta
    20581 caactgtttg ataataaact tcgataccta gatcagctag ctgttctgac aagaaagtgg
    20641 cattcgtatt cacgacttgt cctagtaaaa gttctgttcc gacagctatt atttctgctt
    20701 tcattacttc ccgctccctt atatagtata cgctgtattt ttatattttt ttatttaaaa
    20761 agagggcaag gagctgtgac aaaaatcttg tcacagctcc ttgttccaaa taaacagtgt
    20821 tctcctgcca aaacctcggt cataagtcac aatatacata aaacatgaaa agctgttttt
    20881 tgaaattatc ccttgtgact cagagttaga cggcaggctc acaacctctc cactaaacga
    20941 tacttacatt gatcctttga acacaccgct gtttttgatg aagtaatcca cacctgaata
    21001 gatagtaaag atcagacaag cataaagcat gatttgatct actggaatac cgatcaggct
    21061 gaatgggata ttattgataa acagcaagat aatagcaacc atttgtgtag ccgtcttgac
    21121 ttttcccggc caagctgcag ccatgacttc tccatgttcg acaagtagta aacgcaagcc
    21181 tgtgacggct aattcacgac agacaatgat cgctactacc caaccagggg cctttccttg
    21241 gtcaaccaac atgataaaag cagtcataac tagcatttta tctgccaacg ggtccgcaaa
    21301 cttgccaaaa ttagtgacaa ggcctcgcgc acgggcaatt tttccatcta accagtctgt
    21361 gatactagct aaagcaaaaa taactgcacc tactagctgt gtgacagcca gtgtggtgtc
    21421 tcctacgtta aattgtcccc aatctaaagg taaacctaca accaaaatga aaatcgggat
    21481 catacaaatt ctaagtacag ttaatttatt tggtaaattc acactatcga ctcctttctt
    21541 ccctattcta cgtgactatc agcgaagttt ccaccgatat tatttacttt tccaaatgaa
    21601 tttattcaaa ggagtatttt tattgaaatt gatctttttg aattaacgaa gaaggaccgc
    21661 gacacagatt tgtcacgatc cttctttttt atacctacaa gtaaacagat gcgtaaacta
    21721 atttatacga tcattctgcg tattgaagag taaggttcac attttttgga ctctgattgt
    21781 tttcccctgg attaactggt acggattctc cattcgcttt gatcgttgca ttgcttgctg
    21841 caccaatcgt gatggtcgca tttgttgctg tttccggtaa cacggtactc tgtgtttcat
    21901 ttgctgccag tgtcccttga taaacatagg cattgtctac tagcacacct aaccatacac
    21961 gattgacagc agtaaattca agggttacag gcttggtagc gtctgtgata tttactgcga
    22021 tggcactgcc agaatcttct cctgtagcta ttgccatttt cttttcttca cttgattttg
    22081 ttgttgattc tactgtagaa gactctttgg tctgcgtgct ttgctctgag gaagaggact
    22141 cctcgactga tccttctact ttaagcgaag aagctgtgtc tccgattatt ggatcagctt
    22201 gacgatcttg ccaagtcata tagcccacga caacgacaat cgccaaagca accaatccta
    22261 ataaaatgac aggaagactt gtccaaaagc gacttggatg cgattcttcc tgatgcattg
    22321 cttttctaga agtacttact gtttcaggct gcggacgttc agggaccgat cctgtcaatt
    22381 tgcttttccc atcaaaaaca tcgactaaat ggtctccatc ttctcctaca gcttcagcgt
    22441 attgccgaat aaatgcccgc acgtaaaatt taccaggcaa ttggtcaaaa tcatcattgt
    22501 cgattgcttc caaataacgt ttttgaattt ttgtaatctg ctgtaattca tctaaagata
    22561 tttttttatt caggcgtgct tgccgtaatt tttctccgat ggtttcaaaa gccactcgtt
    22621 catcttctcc agtctgtttg attctccgaa gcatctgctg ttgcaacgaa agacgttatg
    22681 tttgggtgct gtgacaaaag tcatgtcaca gctccttttt tccgaataaa cattgttctc
    22741 ctgccaactc ctcggtcaca agtcacaata tccaataaat ataagaagct gttttttgaa
    22801 cttgttcctt gtgactcgga gttaaacggc aggctcacga cctctttctt aaacggtgtt
    22861 caatcagctg ttcctcggta ttagctcaaa aaccggcaaa atataaggag atatttttcc
    22921 gtatgtttct ctaatactca ggtcaaaacg ctgatttcac aacctcttcc ttaaacggtg
    22981 ttcaaaagct tgcatctgcg gtaataagtc caaccaagtt aaaaacatta agaagctgtt
    23041 tttacttggc tgttcttatt acttgatgca gggcagcttt ttcacaacct cttggtacac
    23101 ggtgttccag aagtagcttc ttcggcaata agccgaaata tcacaaaaat ttgagaagca
    23161 attttcgtaa attccttctt atttcttgaa gctgaccact tctgtcacaa cctctttgat
    23221 tacttcgttt gattttattt taatataagt tgattaaaag agagcatgat ttgttttatt
    23281 ttctcactaa tttttccaac acaactaaga ataccataaa agctgatttt ggaggaggtt
    23341 cctactacaa gtctaaaacg aaatttaaga cttttcctca taaaatactg gtttattttg
    23401 gtctcatgta aaactcgctg aaggcctctt cacttataaa tgcttcccca gctgccagta
    23461 cgtctttcat ttggatcgaa tcgatgattt caggaagatc aaataaagtt cgatcgccaa
    23521 ataaactttg cgtaaattga ttggcaatat attcgatcga atttaatgat tggaaatatt
    23581 gtccaagcat tttcttcttc agcaaatcga gatttgtttc tgacacttcc ggatcatcag
    23641 cgaatccaag aatgatttct ttgacttttt ctgctgcttt ctctggttcg tccgtatctc
    23701 cgctgaagtc cgcaaagtga aattcacgat ccaagctgaa ttcaaaacca aagctgtcat
    23761 cgataattcc ttgattgtac atcgctagat agtttcgaga agtattgcct aaaatcattt
    23821 ggaacaacag attgattgct gttttatagc gtaacagttc tgttccttct tgcggcaatg
    23881 tgtctaatcc tttaatacca agtacaaatt tatctcgtgt aatggctgct tccaatgcac
    23941 tttgtttgat gatttctttt gtgttttcag ggaaataacg tacaatttct tgctttggag
    24001 ggaaattttt tgcttcttgg ttttcccgaa taagtttcat caatttctca ggctccatct
    24061 taccaactac aaataaaacc atattgcttg gctgataaaa cgtccgatag cacgtataca
    24121 agtcttgagc tgtgattttg tcgatacttt caaccgtgcc cgcaatatcg atatgcaatg
    24181 ggtgtgtagg atacaagtta tttagtatgc caaaaaacat ccgccagtta gggtcgtctt
    24241 catacatttg gatttcctga ccgatgattc ctttttcctt gtttacagtt tcttctgtga
    24301 agtaaggtgc ttgtacaaaa tcgatcagag tcgtcagatt cttttctacc tgatccgtcg
    24361 tagaaaacag atagctggtt ttcgtaaaac ttgtgaaagc attggcggaa gctccttgtt
    24421 tcccaaataa ttgaaagaca tcaccatctt ctttttcaaa caacttatgt tctaaaaaat
    24481 gggcaattcc atctggaact ttcacctttt ctttttcacc atagggaata aattcgttat
    24541 cgatcgaacc ataattcgta ctgaacaaac catatgtctt gtgatagtca tttttaggca
    24601 acaaatacac ggtcaaaccg tttggcagta cttcatgata aagtgtttca ttgatttgct
    24661 catattctgt tttattcatt tgcatttcct cctgctaaaa agaagattgc ctgcaattcg
    24721 atttgctcag ctacttgttg tatctctttg atcgttacgc tctccatacg tttcaaccat
    24781 tcttcatcag ataattttgt ttccggcagc cagctgtcca aaaaagaagc ttcgattgcc
    24841 gcttgcggag agtctagaga aagcagatat tggtttctca gcattgcttt tgtctgagac
    24901 agttccaact ctgttatttc accatttcgc aaactttcta attgctcgtg aatcagatga
    24961 agtacttgat ttcggttctt ttcatcgata ccggtttgga cactcatgaa tcctcggaac
    25021 gtatccacgc tactagaggc ataataagct agactttctt tctctctgac attcatgaaa
    25081 agtttagagt gaggaaaacc gccaaataaa ccgttaaaga ccattagcgc aaaacgttct
    25141 ggttcatcgt aatacacatt tgtctgataa gctaggttca gctttgcttg aacgattggc
    25201 tcacgtactt gtcgttcctt cacgatattc acttgaggtt gggtataaaa cagatctgga
    25261 taaactgttt cccgcgactc aaatggtaat tgcccaactg cttcagctgc tttgtccgga
    25321 tcaacatcgc cgacaacaaa aatgtcgatt tgatcatttg ccatcatttc ttgatagtag
    25381 gacgctagcg aactagcagt gatcttgtcc aaatcttcga ctacgcccaa ccctgggatc
    25441 ttttgttccg ggctgttttc aaaataaagt tcttgcaagg cataggaagc aaaagtttgt
    25501 ttatcttcct tcaaactttc caaatataga cgcagattgt tcttttccaa gtcaaacgtc
    25561 aactgatcaa actgatgatt tttaatattt ggataaaata aaacctcttt taaaaaatct
    25621 accgcttgag aaaaaaggtt tggatcattg acatattcac cattcacaaa actgatccct
    25681 gcgtttagcc aatgtaaatt tccttttttt ctaactgata atccaaagct tgcgccataa
    25741 agctctgcaa gttgcgcact taactttgtc tgatccggat aattcaaact atttgtttcc
    25801 aacatgctgc tgagaagtga acgtttcgtg atgacttctt gttgcagacg cgcagtaaaa
    25861 cggataaaaa tccggatcgt tttgtattgt tttgttggta agacatgaag attcacgcct
    25921 tctgccaatt gatacaccat atttatatgc tccttttcac agttgattgc ccgcttactc
    25981 ttttaatggg tcaacctgcc ttttttactt attcctctgc ttgaaattta taagttcagg
    26041 caattcgccg ttttttctaa atgatgttac actttatagt atagcataga tgttttttat
    26101 caaaagaaac agacggctaa aagcgtatat tgttttttta ttttttattt ttcgatatac
    26161 taaagacaaa taaaagaagg gagggtcatt catgatcaaa gaattcaaag agttcatcat
    26221 gcgtggagat gtcttggatc ttgctgtcgg cgttgttatt ggtagtgcgt ttacaagcat
    26281 cgtaaaccaa gtggtgcaag gcttgatcac accactaata ggttggtttg tcgcaatgat
    26341 cacaggtact tctgatttag aaggagcact ttcaattctt gactggtcgc cgacaaaagg
    26401 cgtcacattt gcgtttggta acgttattag tgctatcatt acatttctga tcactggttt
    26461 tgtcttattc ttagttgtca aagcggcaaa ccgtgcgaag aatttacgct ccaaagaaga
    26521 gcaagtggaa gtggaagaaa ctcctactgc agaagattat cttagtgaca tacgcgatct
    26581 tcttgccaaa caagtggcag aagacaatac acatccagta gagcaaacaa atctttccga
    26641 tacttctaaa taataaagaa tctaaaaaaa agaaagccga ttttcagtgt cggctttctt
    26701 tttttagatt cttaacttgc tacttgttcc tttttcatgt cgatatgtgg aatatcatct
    26761 tccaaataca catctgagat tgccttgaat ccaaacgact cataaaaagc ttgtaggtat
    26821 tcttgtgcgc cgatcacgat tggtttttct ggaaaatttt tctggatcat gttaatcgtt
    26881 tcttgaacaa tctttcttcc taaaccatct ttacggttgt cctgatgaac aaggacacgt
    26941 ccaaaatgga tactctccgc ttcttcatat actcgcgtgt aggcaaggat cttcccatca
    27001 gtatcttgaa aaaacgtatg ccaagcttgt ccatcaatgt catcaacttc ttgataagga
    27061 cactgttgtt ccacaacaaa aactgcgatt cgttctttga cgatcgcgta aaactctgct
    27121 gttgacaatt cttcaaattt ctttacctga tattccacta agcaaacgcc ccctgctttt
    27181 ttattcttag cataccgatt cgcacacaaa aaagcaaacg aaccttacga atctcaggct
    27241 cgtttgcttt t
//
LOCUS       DAFEKH010000039        25646 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.040, whole genome shotgun sequence.
ACCESSION   DAFEKH010000039
VERSION     DAFEKH010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25646
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.040"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            133..3660
                     /locus_tag="LP386_001848"
     CDS             133..3660
                     /locus_tag="LP386_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HBL1919083.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3657..7379
                     /gene="addA"
                     /locus_tag="LP386_001849"
     CDS             3657..7379
                     /gene="addA"
                     /locus_tag="LP386_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HBL1919084.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7448..7789
                     /locus_tag="LP386_001850"
     CDS             7448..7789
                     /locus_tag="LP386_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1919085.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8098..9141
                     /gene="pheS"
                     /locus_tag="LP386_001851"
     CDS             8098..9141
                     /gene="pheS"
                     /locus_tag="LP386_001851"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HBL1919086.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9146..11566
                     /locus_tag="LP386_001852"
     CDS             9146..11566
                     /locus_tag="LP386_001852"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HBL1919087.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="LP386_001853"
     CDS             complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="LP386_001853"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HBL1919088.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            13000..13737
                     /locus_tag="LP386_001854"
     CDS             13000..13737
                     /locus_tag="LP386_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBL1919089.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13751..14566
                     /locus_tag="LP386_001855"
     CDS             13751..14566
                     /locus_tag="LP386_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBL1919090.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14579..15226
                     /locus_tag="LP386_001856"
     CDS             14579..15226
                     /locus_tag="LP386_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBL1919091.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15242..15898
                     /locus_tag="LP386_001857"
     CDS             15242..15898
                     /locus_tag="LP386_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBL1919092.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16060..16881
                     /gene="racE"
                     /locus_tag="LP386_001858"
     CDS             16060..16881
                     /gene="racE"
                     /locus_tag="LP386_001858"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HBL1919093.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16884..18239
                     /gene="rph"
                     /locus_tag="LP386_001859"
     CDS             16884..18239
                     /gene="rph"
                     /locus_tag="LP386_001859"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HBL1919094.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18240..18758
                     /locus_tag="LP386_001860"
     CDS             18240..18758
                     /locus_tag="LP386_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBL1919095.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18865..19365
                     /locus_tag="LP386_001861"
     CDS             18865..19365
                     /locus_tag="LP386_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBL1919096.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19645..20565)
                     /locus_tag="LP386_001862"
     CDS             complement(19645..20565)
                     /locus_tag="LP386_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HBL1919097.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20730..21743
                     /locus_tag="LP386_001863"
     CDS             20730..21743
                     /locus_tag="LP386_001863"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HBL1919098.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="LP386_001864"
     CDS             complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="LP386_001864"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HBL1919099.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22828..23268
                     /gene="fabZ"
                     /locus_tag="LP386_001865"
     CDS             22828..23268
                     /gene="fabZ"
                     /locus_tag="LP386_001865"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBL1919100.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23383..24144)
                     /locus_tag="LP386_001866"
     CDS             complement(23383..24144)
                     /locus_tag="LP386_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL1919101.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            24333..25427
                     /locus_tag="LP386_001867"
     CDS             24333..25427
                     /locus_tag="LP386_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBL1919102.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            complement(25513..>25646)
                     /locus_tag="LP386_001868"
     CDS             complement(25513..>25646)
                     /locus_tag="LP386_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL1919103.1"
                     /translation="VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
BASE COUNT         8493 a         4442 c         5408 g         7303 t
ORIGIN      
        1 tttttgcgta tacttaaaaa agtagaaata tcagaacctt aaaaggatat aatttgaaga
       61 atatagaaca aatgttcagt attttttgat ataataaagg agcaccgtat catgtgttga
      121 aggaggaaaa gcatgtcttt acaatttatt cttggaaacg ggaaaaaaga tcaccgtcaa
      181 gtcttgatcg acgaagcatc cgcttggctc gaccaggatg caagtaacca agtatttttc
      241 cttgttccca actacagcaa attcgaacag gaacaagaaa ttttagcgga gatgcgaaga
      301 agaagcggaa aaaaaacttt cagcacaaca aacgttcaag tatttagttt ttatcgtctg
      361 gcttggtatt tgctgcaaca gacaactctt cttacaggaa atgaattatc agaatcagga
      421 tctgcaatga tcttgcgaca gattttagaa aaaaatgagg aagaattaac aatctttcgc
      481 ggagaaatca ataaaagagg gtttattcgt caattacaag aactctacag tgaattgcgt
      541 acaggaaata ttcaaccaga agacctgatg cttttatttg gtgattcacc taatgcagaa
      601 gaccagcaac ttaaaatgaa agacttgaag ctgatttttt cagcttatga cagcgaattg
      661 actcaacgtg cactaacaaa tgaagatgca ctatctatac tagcaaatta tatgcagaca
      721 caagatttca acaacgtcaa atttattgtc agtggttttt ctcgaatcaa tggtcaagag
      781 tatcaattac tgcaggcaat gatggaaaag gggcaattgg ttgtcgattt attgctggat
      841 cgtccttata cagcggatct tccagaagta cttacgctct ttcatgagac tggaaagctt
      901 tatttccgtc tttttcaaag tgcaagagaa cggaaagtcc ctatattagt ggaccgattt
      961 gcaccagagc agactcgtcc gacagagctt caactgctgc aaacaatgtg ggaagagaca
     1021 tctagccaaa agaaagcggc agtacacaaa atagggggac aagagcatct ccatttgtgg
     1081 gaagctgaaa atccaactga agaagtccga caattagctg ttgaaatcag acgactagtc
     1141 agtgaagaaa actaccgtta tcgtgatatc caagtgctga caaaaaatat gtctttatat
     1201 ggaaatatcc ttcggccgat ctttcaagaa atggcaattc ctttttatat cgatgaagaa
     1261 caaatgatgg aaaatcatcc gctgatcgaa tggatcaaca gtctgttcgc tcttgaccgc
     1321 tattcttatc ggctaagtga tattatgcgt tttttcaaaa ctgaattatt tctgtcgacg
     1381 gaagcagaaa ccgaacttga tgaatggaaa caagagcgag atgaattcag gaaaaaactg
     1441 gacatcactg aaaatgtagc acttgcttac aattatcaag gaacttattg gactcgtgaa
     1501 aaagactggc agtttgtggc gtatgatttt gaagcagaac agattgaaga cgtacagtat
     1561 ttggaagaac agtcaaatac gattagacga ttatttcaga aagctgtacc agtatttttg
     1621 aaaaaaataa agaaaagcaa aacaggacaa gaggccgcaa atgtttttta tcaatttttg
     1681 atccaaagtg gcgtacagca acaattattg ttttggcgta atcaggaagt agacagagga
     1741 aacttagaag cggcaagaaa ccatgagcag acatggggag cgctgattga tctgttggat
     1801 gaatatgtag taatttatgg tgaatcggct tttgactggt cactgttcca agaaatcatt
     1861 acaagtggtc tagaaaatct aagttatggt aaaatcccta ccgcaatcga ccaagtgcga
     1921 atcaatcgtt tggaattagt tcgaccaaat caagctgccg tcacttttgc attagggttg
     1981 aatgatcaag tgtttccaga ccgaaaagag acaaaaggat tgttgtccag tgaagaacga
     2041 gaagtattaa atcaggcctt gccagatgga cagtttttat tcgacccatc aaaggaaagt
     2101 atctcttttg agcctttcca agcctatctt gtttttcttt ccggaacaga tcgattatat
     2161 cttagttatg cacaaagcta tgacacagat ggttcgctga agatgtctcc ttatttgcgt
     2221 agaatcacag aatatttatc tgttcccgtc gagagaaaag agcatttgac gatcgaaagc
     2281 gaccctaatt gttatgtagg gacttacaga agcggaatca atacagtcaa taggatttat
     2341 cgattagctt tagatgaaaa aaaacctgta ccaaagcact ggcaaaagct caaagaatta
     2401 gtactgaatt cgtcatggcg aaattttgct ttacagattt ttgaaagtca ggaacattta
     2461 aatgttcctg tttcgatgcc agaaaaaatg gcggaagagc tttatggaaa agagatttat
     2521 acttcaattt cacgtatgga gaatttttat aattgtgaat acaaatactt catgcaattt
     2581 ggtttgaaat tgaaagaacg aactgtttat ggtctaactc cagcagcaac tggtgatttt
     2641 tatcatgaat cattggatcg tttcttcaag ctactgtttt caaaccaatt atccttagtg
     2701 aatatgtccg atgcgcagcg tagagacttt actgaaaaag tgctgcagga agtattcgga
     2761 gaacttcggt ttgagatatt ggatagttct gcaagaatga actatatccg ctaccagtta
     2821 ggacagacga ttcaaaaagt gacatgggct ttgcaaaaac agagcaaaaa tacaggcatg
     2881 catcctcttc agacagagat tctatttggt cagattgctg gagcaaaagg tatcacaggt
     2941 ctggaattac cgttgagtaa tggtggaaaa ctccatgttc gagggaaaat cgatcgaatc
     3001 gatgtagctt ctgaacaaga agatacttgg ctaagcgtcg ttgattacaa atctagcgga
     3061 cgttcattcg atgtcacaga agcttattat ggcatggcta tgcaattatt gacgtatctg
     3121 gacgtagcat tgatggatgc ggtacgtttg actggaaagg cggctgttaa accagcagga
     3181 tcatattatt tacatgttca taatcctgta ttgacggaga cagatgatgt agagaagaat
     3241 acattgaaaa aatttagtta tgatggcgtt tttgtcgatg atcccgctct tttagaagta
     3301 ctagatcatt cactggaagc aaaagaacaa tcactgatct atccagtgaa aaaaaatgcg
     3361 aaagatgaat accaaaaagg tagtttcagt aaagacaaat ttttcacgga agaagaactg
     3421 caactattca tggcgcataa tcgggaaaat atgcggttag ctggagatgc gattacttcc
     3481 ggagaaatca aactaaatcc agcttataaa gataaacagc ggattgcctg cgaattttgt
     3541 ccattcagaa gcatctgtac gtttgatgtg atgctgaaag aaaataatta ccaccgtctg
     3601 gagaaaatag ataaggaaga agcactgcgt agaatattga aaaggagtga agaagagtga
     3661 atcaaattcc tttaaaaccg caaaatgaac gattcacaga tgatcagtgg caagcgattt
     3721 ttgatcaagg agataatcta ttagtctctg cgtctgccgg atcaggtaaa actacagtgc
     3781 ttgttcgaag agtgattgaa aaactaaaaa tgggttttga tatcgatgaa ttattgattg
     3841 tgacatttac tgaagctgcc gcaagagaaa tgaaagaaag aattcaagag gcattacaag
     3901 aatccgtcaa tagcgaaagt gaccctgtac gtagacagca ttttactaag cagttagttt
     3961 tattgcccac agcgaatatc tcaaccttac atgctttttg cctgacagtt attcgacgtt
     4021 attattactt aattgatatt gatccagtct ttcgcatgtt aacagatgaa acagaaacga
     4081 tcttgatgaa ggaggatgtg tgggacgagc tgagagaagc actttatgca gaaaatgatg
     4141 aacgattttt ccaattaaca atgaattttt ctaatgatcg ttcagatgac ggcttgacga
     4201 atctggtgtt ttctctttat gagtttgccc gtgccaaccc tgacccccaa aaatggctag
     4261 aacagttaag cgataattat cgtttgcctg aggggctagc gaaatctcga ttatatcaaa
     4321 aacaaatccg tcctttagtt ttggcagata tataccaatg tgtacagtta tatgaacaga
     4381 tgactcagtt agcacaaggt gaaggattag aaaaaatgca tgagcaagta gctggagaac
     4441 aacagcagat caagaatatc tatgaagcgt tctcgcaaga tcggttagaa gaagcttatg
     4501 ctggtttgga acaactaact ttttcaactt ttaagagcag tcggaaagca gaattgaaag
     4561 aaatttccaa tgaagtcaag ggcatgaggg ataaagcaaa aaaactgatt cagcagataa
     4621 gtaaaagtta ttttcctgtt tccccaagcc aaatggaaga attaacggac aaagcactac
     4681 cgttagtcga agaaatgaca aaagtcacgc aaagcttcat ggacggtttc agtatgcgta
     4741 aacgggaaaa aggtgtgctg gatttcaatg atctggaaca tttagcgttg cagattctca
     4801 cagaaaaaac gaaagatgta tggctgccaa gtgaagcttc aaaacattat cgaaaaaaat
     4861 tcaaagaagt aatggtagat gaatatcaag acgtgaacca attacaagaa gccattttat
     4921 actggctaag agaacccgat gatacaaaag gaaatatgtt catggttggg gatgtcaaac
     4981 aatccatcta ttctttccgt ttagcagatc ctagtttatt tatcgggaaa tacgagaatt
     5041 tctcaaagaa agaaggcgga cgtcgaatcg ttttggctga gaacttccgc tctagaaaag
     5101 aagtcctttc ttttacgaat cttatttttg aacaactaat ggatccagca gtgggtcaaa
     5161 tcaattatga cgaagcagcc aaactgatcc aaggattttc agactttcca gagaatgaac
     5221 agtttgagcc ggaaatcatg atctatgaaa aagaacagga agaatcagag attgagattc
     5281 cgacggatga tatactggaa gacaaaacag aaggcgaact ttttatgaca ggactaaaaa
     5341 ttcgtcaatt aattgattcc tcctttatga tttatgataa aaaatcaaaa aaaagtcgtc
     5401 cgatagagta caaagacatt gttctcttga cacctacaaa gaagaacaac ttaacgattt
     5461 tagagatttt caaaacattg gatattccat tagagatgaa tgatgctcaa aactattttc
     5521 aagcgacaga aattcgcacg atgatctcgc tgctacaatt aatcgataat ccctatcaag
     5581 atattccgct tgcggctgta ttgcgctcac cgatcgtggg tctgattgaa ccagaattag
     5641 ccagcattcg attagctaac cgtgcacata cttactatga tgctgtgctt gcttatcaag
     5701 catcaaacga agatgaatta gcagctaagc tggaacattt tggcaagcaa ctagagcatt
     5761 ggcgagaact tgctcgccgt tcttcgatca ctgacttgtt atgggatatc tattatgaga
     5821 cgggatatct agagtatgtg gtcggtctgc cagcaggggc acagagacaa gccaatcttt
     5881 atgcattggt tgatcgtgcc aaagcttacg agcaaagttc tttcagagga ttataccagt
     5941 tcgtgcgttt cattgaaaaa atgcaagaaa aagataaaga cttagcagaa ccagtcattt
     6001 caatagaaga taatgctgtt cgcgttatga cgatccatgc aagtaaaggc ttggaattcc
     6061 cagttgtatt tttgttagat atgacaaagg agttcaactt acaagacttg cgcaatcggt
     6121 atgcttttga agaaaaactt ggagcaggaa ttcgctatat ggatcctgaa acacgagtgt
     6181 tatatgatac gttaccgttt caagccatca aattggcaaa gcaaaacaaa ttgttgtcgg
     6241 aagaaatgcg taaattgtat gtaggattga ctcgggcaga acaaaagctt ttcattgtcg
     6301 gttcctataa aaataaagag caaatgatcc aaacgtggtc tgaagcagct gatcatgagg
     6361 agttagtttt tgatcctgcg ctacgtttga agggcagaag cagcttgatg aattggattg
     6421 gttacggatt gatccgtcat cctgaaatgc agaaatactt agaggaagaa atttcgactt
     6481 ctcttcttca acattcaaat gcacagtttt ctatttcatg gatgaatcag caatcgatca
     6541 ttgaacaaag acagttgctt gctgaaaaag aactggttaa cttagatcag cagatgaaag
     6601 aagatgaaac tttattagca gattcgttac aaaaacgtct ggcatatgaa tatccttatc
     6661 aagcttcttc acaaaccaca agttatcaat ctgtatctga aatcaaacga ttattcgaag
     6721 atccagatga tacacaagaa tcacgtttga ctctggaaag cagtcagaac aaagcagcat
     6781 cccgtcaatt tcgttatacg caagaacaac tagcagaacc aaaatttttg caaaaagatc
     6841 ggcaagtgtc agcagctgct gttggaactg ctacgcatgc tttgttacaa ttactgccat
     6901 tagagatgcc aactacagag agtatccatc aaaaattaca ggaattggta aggaaacggt
     6961 tagtagacga aaaagtcgcg aaaaaagtag atgtttcttc tattatatgg ttctttcaaa
     7021 cagaacttgg tcaacagctg attgccaaca aagaaaacgt aaaacgagaa caaccttttt
     7081 ccatgctgct tcctgctgac gaagtatttc aagactatcc aaatcaagaa gatgaactat
     7141 taatccacgg aatcgtcgat ggatacctag aagaaaaaga tcatctcaat atctatgatt
     7201 ttaaaacaga ttttatttta catccggatg atccagcaga aatagatgca atcgtccaaa
     7261 aatatcaagg acagctaaga ctttaccaac aagcaatgtc agaagctttg aataagccag
     7321 tagaaaatgt tttcctaatt ttgcttcgag tgaaacaaat tataaacatt aacaaataat
     7381 tataattgag caaacttgac ttatgttttg taaggattat gctatactct gggaagaggt
     7441 gagtatgatg gagctaacac agacagaatt cgttttatgc cctaaatttg aaaaaacatt
     7501 ctctatttta ggaaaaaaat ggaacggatt gattatcgat gtactactcg aaaacggtcc
     7561 gcaacgcttt gttgagcttg cggcaaaaat cccgatggtc agtgatcgag tattagtcga
     7621 acgcttgaag gaattagaaa aagaaggaat agtcactcga aactttgcct gtagcgaaaa
     7681 gagccgttca gaatatctct tgactgaaaa aggagcagac ttgcaaaaag cgatgcgtca
     7741 aatacaagtt tggagcgaaa aatggatcac agaggaagaa tgcggttgat tttgtaaaaa
     7801 aaatcttgta aactatagtc catacgaata agtaaagaac gatgacgaaa aagagtagtt
     7861 tggctaaacc agttcaggga gatctgtcgc agactgaaag cagatcctgt gtttgaaaaa
     7921 tgaagttcac tttccgagtt cgtctgataa aatcagaccg gcaattgtcg ttaacgaagt
     7981 aagagtgcgg tgtaagtcat ttatccgcaa attaggatgg taacgcgaag acctcgttcc
     8041 ttaacaggaa tgaggtcttt ttgttttgta tttggaattt aaaggaggaa caagcacatg
     8101 tctctacaag cacaattaga gagcttgaaa gaagcaacgc tcgtcaaaat cacagcggca
     8161 caagatttaa atgaattaaa tcaaatacgt gttgaaacgt taggaaaaaa aggaccgatc
     8221 acagaagtat tacgtgggat gaaagatcta agtccagaag agcgaccaaa agtcggaagt
     8281 ttcgcaaatg agatccgaga tcttttgaca gaagagatcg agcgaaaaaa acaagtatta
     8341 gaagaagaag cgttaaatgc agctttggca aaagaaacaa tagacgtgac actacctggt
     8401 agaaaagtaa aacatggtac acgtcatatc gtgacacaaa tcatggaaga aattgaagat
     8461 atttttgtgg gtatgggcta tcagatcgta gaaggatatg aagtagaatc tgatcattac
     8521 aatttcgaac ggatgaatct gccaaaagat catccagcaa gggacatgca agatactttc
     8581 tatatttcag acgagatatt gattcggaca catacttcac cagtccaagc acggacaatg
     8641 gaaaaacatg atttctctaa gggtgctcta cgaatgatct cgccagggaa agtcttccgc
     8701 agagatacag atgatgcgac ccacagtcat cagttccatc aaattgaagg gctagttgtt
     8761 gataaaaaca tcacaatggg cgaccttaaa ggaacattag aagtcgtaat gaaaaaaatg
     8821 tttggggaag atcgtgaaat tcgtttgcgt ccaagttatt tcccatttac ggaaccatca
     8881 gtagaagtag atgtcagctg tttcaaatgt ggtggtgccg gttgtaacgt atgtaaatac
     8941 actggatgga tcgaaatttt aggagctggc atggtacacc cgaatgtgtt gaagatgtca
     9001 ggaatcgatc cagaagaata ttcaggcttt gctttcggcc ttggaccaga ccgcgtagct
     9061 atgttgcggt atggagtgaa tgatatccgt aatttctatc aaaatgactt acgtttctta
     9121 agtcagttca agggggagta agaaaatgtt agtttcatat aaatggctca atcgttatgt
     9181 agatttatcg aatgtaacac caaaagaatt agcggataag atgtctgtga caggaatcga
     9241 agtagaggga gtaacggttc cagaagaagg cttgaaaaaa atcgttgtcg gtgaagtcaa
     9301 ggaatgcgta ccacatccag attctgatca cctttctatt tgtcaagtcg atattggcga
     9361 agacgaactg tctcaaatcg tttgtggagc gcctaatgtg aaggttggaa tcaaagtgat
     9421 tgttgcactt cctaactcac gtatcgctgg taatgtaaaa atcaaaaaag gaaaaatgcg
     9481 tggccaagta tcaaatggca tgatttgctc attacaagaa attggctatt cagatagtgt
     9541 tataccgaaa gaatacgctg aaggtatcta ttatatgcca caagaagctg taaatggcga
     9601 tccagttttt ccttatttgg atatggatga ttcgattatt gaattatcta tcacaccgaa
     9661 tcgtgcggat gcattgtcaa tgcgtggcgt agcttatgaa gttggggcaa tttatcgtca
     9721 gactcctaca ttcgatgacg aaaagctggt agaatcctca cgtcctgcta gcgataaaat
     9781 tcaagtggaa gttgaagata aagaagcagt tcctgcttat caaatcagaa tcattgaagg
     9841 agtaagaatc cagccaagtc ctcaatggct gcaaaatctt ttgatgaacg aaggcattcg
     9901 tccaatcaac aatgtagtag atgtgacgaa ctatattttg cttttattcg gacaaccact
     9961 acatgcattt gactacgaca aattgaaatc aaaagagatc tttgtccgcc gtgcaaaaga
    10021 aaatgaaaca ttagtaacac tagatggaga atctcgggaa ttgacaactg acaatctcgt
    10081 cattactaac ggcaaagaac cagttgcttt agctggtgtc atgggagggt tagactcaga
    10141 gatcacgaat gaaacaacaa cagttgcact agaatctgct ttatttgatc caatttcgat
    10201 tcgtcgtaca gcaaaacaat ttaatttgcg tagtgaatcc tctgcacgtt ttgaaaaagg
    10261 aatcaaccat gcgactgttg gagaagccag tgaggttgct gcagcaatga tcgtttctct
    10321 tgcgggtggg gaagttctac aaggcgcggt caaaggctca gagatcaaag cagaagacgt
    10381 atcagtgaag atttcacttg aacgcatcaa tcaatattta ggaacatctc ttgtcgttaa
    10441 agaagtaaat gagatttttg aagcacttgg atttagctat gaagaaaagg agtatgttta
    10501 ttccgtagta gtaccaccaa gacgctggga tatccaaatc gaagcagata ttatcgaaga
    10561 agttgctcgt atttatggat acgaccagtt gccatctaca cttccaagtg gagaaacggt
    10621 tgctggaagc ttgtcaaaag aacaagaaac tactcgtaaa attcgtacaa tctttgaagg
    10681 aagcggattg agcgaagcaa tcagttatgc attgacaaca gaagaaaaat caagacagtt
    10741 tgttataaat gaaagtaata ttacacgttt ggactggcca atgagcgaag aacgttctgt
    10801 attacgaatg aatttgatca gcggactatt agatgatatc agttataaca ctgcccgaaa
    10861 aaatacagag attgctttat atgaaattgg tcgggtgttc ttccaagaaa atgatccacg
    10921 tacacatctg ccgcaagaag taaaacatgc agcaatcgct atttctggta tttgggaaga
    10981 aaaagattgg cagacgaaag ctcaaaatgt agactttttc accatcaagg gtcttttaga
    11041 aaacttattt gaacaactag gcatcactga agatgtccat tatcaaacag tgacagaaat
    11101 gaaggaaatg catcctggaa gaactgctgc gatttacctt ggcgaaaaat ttattggttt
    11161 tgtcggtcaa gtgcatccaa cgattacaaa aagttatgat attccagaaa catatgttgc
    11221 tgagtttgat ttatctgcta tagtggaagc tgctcaaaaa gggatcgttt tcgaagcagt
    11281 gacaaaattc ccagcagtca gccgggacat cgctttgctt gtaaaagaaa ctgtgacaaa
    11341 tcaggaatta acagaagtta tccgttctgc tgccggaaga tttttaacag atatccaatt
    11401 atttgatgtc tatcaaggag aaaacattga aaaaggacat aaatccatgg cgtatagcct
    11461 gacattcgtc aacccagaag caacattgac agatgaagaa atcaataaag caatggaaaa
    11521 agtcgaaaaa gcgttggtag aaaacctaga ggcaagtatt cgctaagaag gaaaatatag
    11581 taagtaacga tcaagtagct tttgaagacc atacatttga aaaaaagatg tgacacaact
    11641 tcgtcacatc tctttttttg attttaaaaa aggaatagca cagagacgag ataaaaaaac
    11701 aggcctttac agcctgcttt tttagagtaa atgaattaat ggaagtaatt gattcccatt
    11761 gctgatttta cttcagaaag tgtttgtgca gctactttag cagcttcttc actaccttta
    11821 cgtaagattt ccataacagc tgaaggatct ttttccaatt cttctcggcg cgcacggatc
    11881 ggtgcaaatt cagcttccaa tacatcaatg aggtatcgtt tgatctttac atcaccaagt
    11941 ccgccgcggc ggtaatgagc tttcatttct tcaattgctt ctttatctgt tccgaataca
    12001 tccaagtagg tgaagaccat attcccttct acttgtccag gatcttgtac atggatgtgg
    12061 tttggatcag tatacatact catgactttt ttctgtaaga catcggcagg atcggagata
    12121 taaataccgt ttcctaacga tttactcatt ttgccatttc catcgattcc aggtaatcta
    12181 cccattcctt ttggtgggaa tacgcctttt ggttccacca agacttcacc atatgtatga
    12241 ttgaagcttt gtacgatttc ctgtgtctgc tctagcattg gtttttgatc ctcaccaaca
    12301 ggtacaagat tcgctttgaa tgcagtgata tctgctgctt gagaaacagg atagataaag
    12361 aatcctgtag gcacgctttc accgaatttt ttttgttcga tttctgtttt gacagtcgga
    12421 ttgcgccgaa cgcgtcctac gctgactaag ttcaaataat acatggttaa ttcagctaat
    12481 tccggaattt gtgattggat aaataaagta gattttgcag gatctaatcc cacggctaaa
    12541 tagtctaaag caacttgcaa gacatttgat gaaaccttct caggattttt agcattatct
    12601 gtcagtgctt gcatgtcagc aatcatgaca aacagttggt tgtcttcatc tgcctgcata
    12661 gccactcggg tttttagaga accgacgtaa tgccctaaat gcagcttccc agttggtcga
    12721 tctcccgtta aaataatatt tttcaaaaaa gacacctctt tacgatttgt aagtctgagc
    12781 acttaatatc ttaccgtttt tcctgaaaag aaacaacagt tcctaaggaa aaaacaagga
    12841 aagaggataa aataactaat agattagaaa tggaagaaat atttatggga gaataaacgt
    12901 tctaagaaac tttacaaatt actaaactat cagatataat gtattttatt atacatcttt
    12961 aaaagaaatc ttactaaata ataatgggag tgtaattcta tggcaatgat taaatttgat
    13021 cacgtggata aatattatgg caagttccac gcattaaaaa atatcaatct cgaattcgag
    13081 aaaggagaag ttgtcgttgt cattggtcct tctggttcag gaaagagcac gatgcttcgc
    13141 tgtatcaatg gattagagac gatctcttca ggtaagctgc tgattaatga tactgacttg
    13201 catgataaaa agacaaaact gacagaagtc cgaaaaaaca tcggcatggt tttccaacat
    13261 ttcaatttgt acccaaataa aactgttctg gaaaacatca aattagcacc aatcaaagtg
    13321 ttgaagcaag accaggcaac tgcagtcaaa aacgcggaga aatttttgaa aactgtcaat
    13381 atgttagata agaaagattc ttatccttcc atgttatccg ggggacaaca gcaacgggtg
    13441 gcaatcgcca gaggtttagc gatgaatcct gagatgctgc tgtttgatga acctacttct
    13501 gctttggatc cggaaatgat tggtgatgta ttagacgtta tgaaaaaatt ggctcatgac
    13561 ggtatgtcaa tgattgtcgt gacacatgaa atgggctttg ccaaagaagt ggcggatcgt
    13621 gttatcttca tggctgatgg agaagtattg gaagacagca gaaatgtgag agactttttc
    13681 gaaaatccaa atgaagtccg agcacagcaa tttatcagta aagttatcaa tcattgatag
    13741 gaggaaaaag atgcgcaggt taaaaaaaat acgcctgatt ttccttttag gcattgcttt
    13801 tcttgcacta gccggatgta aaggaaatgg gttggcaaat gaagatattt tagagcgaag
    13861 caaatctacc aatgaaatca tctggggtgt caagtatgat actcgattat ttggaatgat
    13921 ggatattgag agcagaactg tacaaggatt tgatgtagat attgcaaaag caatcactaa
    13981 aaagatcctt ggtgacaatg gaaaaacaga atttgttgaa gtcacttcta aaactcggat
    14041 tccattattg aaaaacggaa atatcgatgc aattattgca acgatgacga tcacagatga
    14101 acgaaaaaaa caggttgact tttcagatgt ctatttcgat gctggccaag ctttgttggt
    14161 aaagaaagga agccaaatca aaagtgtaga tgatttgaat gcttctacaa cggttctagc
    14221 agtcaaaggt tctacatcgg ctgcgaatat ccgacagcat gcaccagatg caaaaatttt
    14281 agaattagaa aactatgcag aagcatttac tgctttacaa tctggtcagg gagacgcgat
    14341 gactacggat aatgcgattt tgttagggat tgcagatgaa aatccagagt atgagttagt
    14401 tggtggaacg tttactaatg agccttacgg gattgcgatc aacaaagggc aagaaaactt
    14461 cttgaaagct gttaaccaag cgctagagga aatgcatgca gatggcacat acgataaaat
    14521 ctatcaaaaa tggtttccaa atgaaactga aggaaaagta gagtaagggg gagaggcaat
    14581 gagcgaattg atacaaactt atggaccaat ctttgtcgac gggttcaaga tcacattgtt
    14641 ttcgagtgtc ttagcacttg tgtttagttt gattatcgga acgttaatgg caatcttcca
    14701 attatcaaag aataaagtag tgagcgcctt agcaaaggca tatgtagaat tttttagaaa
    14761 cattccatta ttaatcatcg tgatgttttt ttatgttgtc gtaccgattt attggtttaa
    14821 tctagatgga ttccaagcag gtacgattgg attaacgatc tatacatctg cttttattgc
    14881 tgaaacagta cgttcaggga ttcaaaccgt accaaaaggt caaacagaag caggactatc
    14941 ttctggtttt acctattcag aaatcatgcg ttatattgtt ttaccgcaag cattcaaaat
    15001 cgttatcccg ccattaggca accaatttat caacctcgta aaaaactcat ctattttagc
    15061 aatcgtagct ggtttagatt tgatgtatca aggagacttg atcgctagtg aaacattcaa
    15121 taccttcgat acgtatatca tcgttgggtt attttactta gttatcacgc taccgttatc
    15181 ttacttaatg gtttatcttg agaaaaaatg ggcggttcgt tcatagaagg aggggaaata
    15241 catggatttt agcggcgctt tttcatggat gaatatccgt tttttattgg aaggattaaa
    15301 ggttactgtt gaagtttcat tgttttcgat catttttagt ttcttgatcg gtggtctgac
    15361 aggtgtgatt cgttttgcga atatcccttt cttttccaaa atccttggtg tagtgattga
    15421 tattatacgg aatcttccat tattattgat cattttcttc acttactttg ccttacctca
    15481 aatcggcatt cagatgaaca tcttctggtc cgctgtcgca gcattaacga tttttgagtc
    15541 agctatgttg tcggaaattt tccgagctgg actcaatgct gttccaaaag gacagatgga
    15601 agcaggatta tcaacgggac tgacttatgt agaatcgatg cgaacgatcg tgttaccgca
    15661 agcatttaaa tcaatgatcc cggcaattgt gagccaattg atttcactga tcaaagatac
    15721 ttcattagca gtaatcattt ctttacctga actttctcat caggcacgta ttatttatgg
    15781 acagaacacc aattatgtgc ttccgatgtt catcatcatg acacttatgt acttcgtggt
    15841 atgttacgcg ctttctctgc tttccggtta cttggaaaag agacggtaca gttattaata
    15901 gatgattctt ttagcggttg tggcaaacta aagtcacaac cgcttttcct ctttccattc
    15961 gaaaaaaaga gatttcgatt gttttaagca agtaagagca cttgaaaatt cacgctaaaa
    16021 agtacacaat agggaggata gaatttattg aaaaaaagga tgatacgatt gacagataat
    16081 cgccctatcg gatttattga ttcaggtgtc ggcggcttga ctgtagtaaa agaagccctg
    16141 aaacaattac cgaatgaaaa tattttattt gtaggagaca cagcacgctg cccatatggc
    16201 cctagacccg cggaacaggt aatccagtat acttgggaaa tgacggatta tctggtggag
    16261 caaggaatca agatgctggt gatcgcctgc aataccgcaa ctgcggtggc tttagaagaa
    16321 atcaaagctg ctctttctat tccagtcatc ggtgtgatcc ttcccggtac tagagcggca
    16381 gtaaaaaaaa cacaaaataa acaagttggc attatcggta cgattggtac ggtaaaaagt
    16441 caagcttatg aaaaagcact gaaagagaaa gtaccagaat tgactgtgac aagtcttgct
    16501 tgtcccaaat ttgtttcagt tgtcgaaagt aatgaatacc attcatcggt ggcgaaaaaa
    16561 attgtggcag aaacattagc tcctttaacc actaaaaaaa tcgatacatt gattttggga
    16621 tgcacccatt atccattatt acgccccatc attcaaaatg taatgggaga aaatgttcaa
    16681 ctgatcgatt ctggagcaga aacagtaggt gaagtatcta tgctgttaga ttatttcaat
    16741 ttgagcaatt caccgcaaaa tggtcggaca ttatgccagt tttatacaac tggctctgcc
    16801 aaacttttcg aggaaatagc tgaagactgg cttggaatcg gacacttaaa tgtagaacat
    16861 atcgaattgg gaggaaaata aggatgcgtc atgacgggag aaaagcccaa gagcttcgca
    16921 aactggagct tcaaacaaat gttttcaaat atccagaagg atcggtagtg atccgttttg
    16981 gtgatacaac agttatttgt tctgcaacaa tagaaaattc tgttccccct tttttgagag
    17041 aaacaggaac aggatgggtg acagcagaat atagtatgct gcctcgagca acgagtacga
    17101 gaaatcgtag agaaagcagc aaagggaaac tttctggtag aacaatggaa atccagcgtc
    17161 ttattggtcg ttccttgcgt gcagtagtag acttggaaaa attaggagaa cgtagtatca
    17221 tcgtagactg cgatgtgatc caagcggatg gcggtactag aacagcaagt atcactgggg
    17281 catttgtggc attgaaatta gccattgaaa aacttttaag agaaaaagaa ttgtcagaag
    17341 atccaataaa agaacatctt gctgcagtta gcgtaggaat cttaccagat gggacttgcg
    17401 tcacagattt ggattaccaa gaagattccg cagcacttgt agacatgaat cttgtaatga
    17461 cagaatctgg aaaattcgtg gagattcaag gaactggaga agaagcaacg tttgatggtg
    17521 aacagttgaa tgaaatgctc ttttttggaa aaaacgcgat tgaagatttg atcaaagagc
    17581 aaaaacatgc tttgctaaca gagtttgctc aaaatgatga gcggatagaa gaaacaaaaa
    17641 caatcatcat tgcgacaaga aatccaggaa aagcagaaga gtttcgaaat atgttcaaag
    17701 aagcgggata tcatgtaaaa acattacttg actatcctga attgccagat gtggaagaaa
    17761 ctggcagcac atttgaagaa aatgcccgat taaaagcaga aacgattgca caattgcttg
    17821 atcagccagt cttagcagat gattcaggtt tgaaagtgga tgctttaggc ggtatgccag
    17881 gaatctattc tgcacgtttt gcaggggaac aaaaaagtga tgcggggaat aacgccaaat
    17941 tattatatga attgacagat gtgccggatg aaaaaagaac agcacaattc cattgtacgt
    18001 tagtattcgc ggcacccaaa aaagacagcc ttgtagtaga agcggaatgg cccggtcgag
    18061 tagcccgtat accatctggc gaaaatggct ttgggtatga tcctttattt atcccagaag
    18121 gtaagaaaca aacagcagca gaattatcga gcgaagaaaa aaacaagatc agtcatcggg
    18181 ctcaagcaat gaaaaaattg agtgccgagt ggaaacaatg gctggaagga gagagataga
    18241 tgcggtattt agtagtaagt gataatcatg gagacagaga tatcctcgtt gacttagtag
    18301 atcgttatcg ttctgaagtg gatatctttt tccattgtgg tgattcggaa ttagaagctt
    18361 ctgacccatt atgggataca ttccaagtgg ttcaaggtaa ttgtgattat ggaccaggat
    18421 tcgaacagaa aaaagtgatc caaactggtc aggatacagt attcatgact cacggtcatt
    18481 tatcgaatgt ccgatttggt ttgacacagt tagcaatcga agctcgagct gcaactgccg
    18541 atatggtgtt ttttggtcat acccatcaaa taggctgtga gatggatcag aaaatcctgt
    18601 ttttgaatcc tggtagcatt tctcagccta gaggcccgat ccaaatccca tcatatgctc
    18661 ttatcgaaag tttagatgac caaatttctg ttcaatacta taaccgtgcc catcaggcag
    18721 ttgaagagtt ggccttttct ttttcgagag agcgctgaat aaaaaaactc taatttttaa
    18781 taaaaataag ctttatttta tgaattttgc atccggtttc ggtaaaatag tagtgttgaa
    18841 tgaaatagaa atggaggcca tcagatgatt ggacctatag taagagaaat gctgctggaa
    18901 aatcaggaaa cgtttttgat tcctgcagaa aatgtggcaa atgttatgta tcatcatcca
    18961 ttgtcccatg gtttacttgt gttatcgaag gtcggttatt ccaaaattcc tgtattagga
    19021 aaagatgatc actttgtagg actagtaagt ttatcagatg tggtcaataa aatgattgac
    19081 ttgcaaacaa tcagcatgga cccgttagaa ggactaacgg ttgctgatgt gacagaaaca
    19141 gatgttccga caattgatga aaattgggaa ctagaagaag tactccattt gttagtcgat
    19201 tcgccttttt taccggttgt cacagaagat cggattttca aaggaatcat tacaagaaaa
    19261 gagctgctta aagccgtaaa cttcatggtg catgaattag aacgtcgtaa tatattgtct
    19321 ccgaaaatcg aagaattaaa agaacaaatc gatatcgtga gctaaagaac gagaaactaa
    19381 aagataatca aaaaataagt agaaaaaaca gcgtaccagt tttgacttta tcttgaaaaa
    19441 gaggctggga caaaagcgtt taactccaag aaataagaag gaattcacga aaattgcttt
    19501 tcaaattttt gtgaatttca gcttatttcc gaaggagttg cttctgcttc cgccgtttat
    19561 acgtgtttag agcgtgggac aaaagtgttc tttacttttg tcccacgctc tttttagtga
    19621 gattcgttgc atcgtttgtc caaattattt tccgacagca attggactgt tcggaatcgt
    19681 gaaaccagaa gctgtcaatt ctttgacata ggagctcaag aactcttctt ttaaggcata
    19741 ttgttttccg ttcaatgcgt agcagaccgt acgaatcgca aaattgctgt ttccaagatc
    19801 cactaatcca aagatagaag gttcagtttg gagctcttct tggtattttt cagctaatgt
    19861 acgatttact cgatcaatga tctcatagat tttgtcatat ccttcttcag gaacaatccg
    19921 aatatctaaa agtacttgca tatttgcacg agagagattg ctgatcgtgg tgatgtttcg
    19981 attcgggatg aaatggacag taccatccgt tgctttcagc tgaagggtac ggataccaac
    20041 agatacgacg gttccttcaa tcgttaagtt tgctagcttg atgtagtccc caacatccat
    20101 ctgttgttcc atgataataa aaaatccggt aataacatca ctcatgaacc cttgggcacc
    20161 aagaccgatt gccacacctg caattccggc accagccaaa agtgatccga tcggcacacc
    20221 gatagcagat aaaattgcat agataaaaaa gaaaccaagg gtataatgaa aaatagtatt
    20281 taaaagacta tgtaaagtct ttaagcggct ctcgtttaga atggcttttt tagaatactg
    20341 attaaaagac ttatcaatca gatattttcc cacacggtga agaatccaaa aaaggacgat
    20401 caaaaaaatc agatataaac ttttttggat aaaggcagcc aaaatggcgt cccaatcaat
    20461 cccgtcccaa aaccgctgaa acgcatttac tttgctgaca gcttgatctg tcaatgtctc
    20521 gccagaagag tctgtcgtac cggcagttgc taataatgaa aacataaaat cctcttttct
    20581 aaaatttgat tctttctgta ttgtaccaag aagttttcaa aaaaggaaat agcaaaaata
    20641 actataatga aggaaaaaag ctgaaaataa aatgacaaat aatatggata atgataaaat
    20701 gtggagaaaa taacgaaggt ggtaagtata tgcaaatcga ttggaacaat ctaggttttt
    20761 cttatatcaa aactccttgg cgttttattg ccaaatggaa agacggacaa tgggaagaag
    20821 gagaattgac agaagataat tacctgacga ttcatgaagg ctctccagcg cttcattatg
    20881 gtcagcaatg ttttgaaggt ctaaaagctt atcgtcgaaa agacggcaag gtcaatctct
    20941 ttcgacctga acaaaatagt cgacggatga atcaaagtgc tagacgattg ctgatgccaa
    21001 tggtccctga aaagatgttc gttgatgctg tcaagcaagt ggtaaaagca aatgaagatt
    21061 ttgtgccgcc ctatggaaca ggcgctacat tatacttgcg ccctttactg attggggtcg
    21121 gtgaaaacat tggtgtccat ccagctccag aatatttatt tgtcgtcttc tgtacgccag
    21181 taggagcgta tttcaaaggt ggactaaaac caacgaattt tattgtatct gattacgatc
    21241 gtgctgctcc taaggggact ggtgcagcaa aagtcggcgg aaattacgca gcgagtttac
    21301 ttccaggaac agaagcaaaa gaactggatt actcagattg tgtttatctt gatccagcca
    21361 cacatacgaa aatcgaagaa gtaggtgcag caaatttctt tggaattaca aaagacggaa
    21421 aattcatcac tccgcaatcg ccctctatct taccaagtat cacgaaatat tccttgttgc
    21481 agttagctga agaacgacta ggactgcaag caattgaagg agatattttc attgatgatc
    21541 tagatcaatt tgcagaagct ggtgcatgtg gtacagcggc tgttatttct ccaatcggtg
    21601 ggatttatca caataacaat cttcatgtat tttatagtga aacggaagta ggaccagtaa
    21661 caaaacggtt gtatgatgaa ttgacaggta ttcaatttgg agacatagaa gcaccagaag
    21721 gctggattga agtcgtggaa taatttcaaa gtaatgagtt gaaaaaaacg taaaaagaaa
    21781 aaatcaggaa gagactttaa aaagtttttt cctgattttt atatgtttta ctttaaagaa
    21841 tgcaacaaaa gtttatgaaa gatggacacc tttgtcaacg tagataatat caccgatgat
    21901 tccgctggaa agtgggctga ttaagaaagc acaagcatta ccgacttctt cgatcgtcac
    21961 accttgctga tcaggcgtac gagattcaga taactggatc agtttttgat agtctttaac
    22021 acctgtgaca gctaatgttt tgattgcccc agctgagatt ccattgaccc gaattccttt
    22081 aggcgagaac tcagctgcca aataacggat agcagcttca agagaagctt tcgcaatacc
    22141 catcatgtta taattcggga ttgcgcgttc tgaacctaga taagtcatgc taacgatccc
    22201 gctgtttggt gcaagaaacg gttgtgcgta ttttgataca gcaattaaag agtagctgct
    22261 gatatcttga gctaattgat agccgtctct ggaaatatca gacacatttc cggacaattc
    22321 ttctttgttg gcgtaagcaa ctgcatggac aaggccgtgg atctccccag catattcacc
    22381 gatggcattc attgcttttt cgatgctttc gtcgctagaa acatcacatt ctacagtgaa
    22441 tgcttcttcg ccgaccaatt tgactaatga ttttttcatt cgttcatttt ggtaagtata
    22501 gataatttct gccccttgtt tcaacattgc ttcagcacaa ccccaagcaa tgcttttttt
    22561 gttagcgacg cccataatga cgattttttt tccttctaga aatgacataa tgactctcct
    22621 ttgtttctga taaaaatttg atagtcgtaa aaaaatagag aataatagct aaaataactt
    22681 cttgatttct taattattag tcaaaatgtt ttgattgtca aactattttt tcttaaatta
    22741 aaaaaagatt gctaaatatt taggaatatg atactttgat agtcaaagta atgaaaatgg
    22801 caattgcctg aaagaaggag tttaattatg tcttacgtat tatctgctac tgaagtaatg
    22861 gaattgattc ctaatcgtta tcctatttgt tatattgatt atgtagatac tttagaacca
    22921 ggaaaaaaga tcgttgcgac aaaaaatgta acaatcaatg aagatttttt ccaaggtcac
    22981 tttcctgaca atccagtgat gccgggtgcg ttgattctag aaacactggc acaagcaggt
    23041 tcgatactta tcctaaaatc agaagagttt ctaggaaaaa gagcttatat cggtgggatc
    23101 aataaggcca aattccgtca aaaagttgtt ccaggagatg tgctgaaatg tcattttgaa
    23161 atcaccaaaa tgaagggatc agtcggtaca gcgttatctg cagcatatgt agatgataaa
    23221 aaagtctgtg agtgcgagtt cacgttcatc gtcaaccaaa atgcttgact ataaaacctg
    23281 atatagcaaa acaaaaggaa gcttacttgc tttttatgta aaaagaagac gcctgaatcc
    23341 tagcatacgt tgtcatctat gcaggattca gacgttattt ttttattttt gttttgcttc
    23401 ttgcagtata ttgattttat cgatttttac ttcttctttt ggtttgtctg aactatctgt
    23461 ttcgatattt gcaatagcat ccacgacatc cattccttca atcacttggc cgaagacagt
    23521 ataatggcca tctagtgaag gataaccgcc gtttttataa gcgtcgatga ttgcttgagg
    23581 atagtcgtct tttaaaagac catcatgcat atcatctgta ttttgaacga taaagaactg
    23641 gctgccgtta ctgttaggat cttgtgagcg agccatagat aacgcacctc ttatattata
    23701 aaggtggttg ttgatctctg tttcaaatcc ttctccccaa atgctttccc ctccagtgcc
    23761 atcgccttta ggatcgccac cttggatcat gaaatctttg atgacgcgat ggaaagtcag
    23821 tccgttgtag taaccgtctt ttgcatgtgt cataaagttt tcaaccgctt ttggtgcgtg
    23881 ttcgggaaat aatttgattt tgattgtgcc tttattcgtc accatttcga ccagatcttc
    23941 attttcggcg acatctttcg tcaattgtgg taattccaat gcgttcaaat cgacgctact
    24001 ggcagtcgtg ctttccgcag tagatgtact ttttgaactt tctgtagacg aactagaaga
    24061 agtcgtgttg tttgcagaac aaccagcagc aaacagcaat gctgctgcta aactaatact
    24121 taaaataact ttatttttct tcataactgt tcctttccaa tttactattt tgttatcttt
    24181 aatgataaca aaatagaggg aaaataccta cttaaattat tggaatttat catttatttt
    24241 aaaagaaaaa gaaaaggtgt agaccattta ctttgtgttt gctataatgt aagtggatac
    24301 aaaaacgaaa agatgcagga ggaaatggta atatgggaaa attaggaatc tcgatttatc
    24361 cagaacggtc aacatttgaa aaggacaaag cgtacttgga tttagctcat aagtatgggt
    24421 ataaacgggt ttttaccagt ttgctgcaga tcaatgatga taaagaaaaa gttctttcag
    24481 aatttaaaga agtagttgat tacgcgaata gcctaggcat ggaagtaatg gttgatatca
    24541 atccagcgtt atttgaacag ttggagattt cttacgatga cttatctttt ttccataaga
    24601 tgggtgccta cggggtccgc ttagatatcg gattcacagg agcagaagaa gcaaaaatga
    24661 cgcgcaatcc ttttggtatc aaaatcgaga tcaatatgag ttcgggcacg aattacgttg
    24721 acaacatcat gagttattcg ccaaacacgg ataatttatt aggttctcat aatttttatc
    24781 ctcatcgata ctctggttta ggatacgaac actttgtttt ttgttcagaa aaattcagaa
    24841 aatataattt gaatacgatg gcattcgtca attcgcaatc tgctgagttt ggcccttggc
    24901 ctacgcaaga tggcttgtgc acgctggaag accaccgaga tcttgaaatt gcgacacaag
    24961 tgaagcattt aatccttaca ggattgattg atgatatttc tattggaaat gcgtacgcaa
    25021 gtgaagaaga attgaaagaa atggcagaag catttaacgc ggattatcca acattgaaag
    25081 tagatacgga agaaggtatt acagaaaacg aacgaatctg cttgtttgat aaccttcata
    25141 gttatcgagg ggatcgctca gaatatatcc ttcgttcaac gatgactcgt gtatactaca
    25201 aagataaaga tttcccgcct cataatacgc gagatatgca tcatggggat gtactgattg
    25261 acaatgaagg gtacggtcaa tacaaaggag aaacacaaat cgccttgaag gatatgaaaa
    25321 acgacggacg tgtcaatgtt gtaggaagaa tctccgatga cgaattattc ctccttgact
    25381 ttttgaaacc atggtcaagc tttaaattaa ttgaaaataa aaaatagata attagttatt
    25441 gcagaaataa tccgctagaa atagccagtt atttctgctt ttttattttg tttttttata
    25501 ggttatgatt tgtcaaatta agctagaata aaatgcttct tgtacatagc tcaaaaatat
    25561 ttcgattggt gttctgtaat tcaatgattt tcttggaata tgattacgtt gattgctgac
    25621 actggaaata aatgtctgat tcactt
//
LOCUS       DAFEKH010000040        24271 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.041, whole genome shotgun sequence.
ACCESSION   DAFEKH010000040
VERSION     DAFEKH010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24271
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.041"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..572
                     /locus_tag="LP386_001869"
     CDS             <1..572
                     /locus_tag="LP386_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBL1919104.1"
                     /translation="ASRIAIMSEGRVIQFDTPENILRHPANDFVEELIGEDRLLQAKP
                     NATRVGEVMLNTAITITPEKSLQEAIKLMREKRVDTLLVTDNSNVLKGFIDVETLNKK
                     RGKVSSVGDILNKHVFYVKESAYLRDTLQRILKRGLKYVPVVDEQNKVVGILTRASLV
                     DIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            576..1217
                     /locus_tag="LP386_001870"
     CDS             576..1217
                     /locus_tag="LP386_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1919105.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            1214..2131
                     /locus_tag="LP386_001871"
     CDS             1214..2131
                     /locus_tag="LP386_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL1919106.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            2128..2799
                     /locus_tag="LP386_001872"
     CDS             2128..2799
                     /locus_tag="LP386_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1919107.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(3340..3828)
                     /locus_tag="LP386_001873"
     CDS             complement(3340..3828)
                     /locus_tag="LP386_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HBL1919108.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(4029..4295)
                     /locus_tag="LP386_001874"
     CDS             complement(4029..4295)
                     /locus_tag="LP386_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBL1919109.1"
                     /translation="MSNYTVAIKNSAKVELRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(4295..4558)
                     /locus_tag="LP386_001875"
     CDS             complement(4295..4558)
                     /locus_tag="LP386_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBL1919110.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            5034..5219
                     /locus_tag="LP386_001876"
     CDS             5034..5219
                     /locus_tag="LP386_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBL1919111.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(5361..7184)
                     /locus_tag="LP386_001877"
     CDS             complement(5361..7184)
                     /locus_tag="LP386_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HBL1919112.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(7782..10487)
                     /locus_tag="LP386_001878"
     CDS             complement(7782..10487)
                     /locus_tag="LP386_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HBL1919113.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(10793..11740)
                     /locus_tag="LP386_001879"
     CDS             complement(10793..11740)
                     /locus_tag="LP386_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HBL1919114.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            11930..12199
                     /gene="rpsN"
                     /locus_tag="LP386_001880"
     CDS             11930..12199
                     /gene="rpsN"
                     /locus_tag="LP386_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBL1919115.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(12375..12737)
                     /locus_tag="LP386_001881"
     CDS             complement(12375..12737)
                     /locus_tag="LP386_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBL1919116.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(12748..13869)
                     /locus_tag="LP386_001882"
     CDS             complement(12748..13869)
                     /locus_tag="LP386_001882"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBL1919117.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(13885..14235)
                     /locus_tag="LP386_001883"
     CDS             complement(13885..14235)
                     /locus_tag="LP386_001883"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HBL1919118.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(14365..15876)
                     /locus_tag="LP386_001884"
     CDS             complement(14365..15876)
                     /locus_tag="LP386_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBL1919119.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(16198..17550)
                     /locus_tag="LP386_001885"
     CDS             complement(16198..17550)
                     /locus_tag="LP386_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HBL1919120.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLAATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(17703..18779)
                     /locus_tag="LP386_001886"
     CDS             complement(17703..18779)
                     /locus_tag="LP386_001886"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBL1919121.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            18975..20720
                     /locus_tag="LP386_001887"
     CDS             18975..20720
                     /locus_tag="LP386_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HBL1919122.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(21000..21437)
                     /locus_tag="LP386_001888"
     CDS             complement(21000..21437)
                     /locus_tag="LP386_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HBL1919123.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(21421..22794)
                     /locus_tag="LP386_001889"
     CDS             complement(21421..22794)
                     /locus_tag="LP386_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919124.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(23116..23604)
                     /locus_tag="LP386_001890"
     CDS             complement(23116..23604)
                     /locus_tag="LP386_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1919125.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(23626..24228)
                     /locus_tag="LP386_001891"
     CDS             complement(23626..24228)
                     /locus_tag="LP386_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBL1919126.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         6959 a         5164 c         4487 g         7661 t
ORIGIN      
        1 tagcaagccg tatcgccatc atgagtgaag gccgtgtgat ccaatttgat acaccagaaa
       61 atattttacg tcatcctgca aacgatttcg tagaagagtt gattggagaa gatcgcctac
      121 tacaagccaa gccaaatgcg acaagagtcg gcgaagttat gctaaataca gcaatcacga
      181 ttacaccgga aaaatcatta caagaagcaa tcaaactgat gagggaaaaa cgtgtagata
      241 cgttgttagt taccgataat tcgaatgtat taaaaggatt tatcgatgta gaaacgttga
      301 ataaaaaacg aggaaaagta tccagtgtcg gcgacatttt gaataaacat gttttttacg
      361 taaaagaatc cgcctatctt cgtgatacct tgcaacgcat tttaaaacgc gggctgaaat
      421 acgtgccggt cgttgatgaa cagaacaaag tcgtaggtat cctgactcgt gcatcattag
      481 tggatatcgt ctacgatgtg atttggggag aagatcccgc aactactgat gttgcagagt
      541 cagctactcc tgaagaatct aaggaggtct gacctatgca gcagtttttt catcagcacg
      601 gttcagaaat tctctcaaaa ggttttgaac atctttatat ttcaggactt gctttgatca
      661 ttggtatcat cattgctgta ccgcttggtg tcttactgac acgttttcca aaagctgcca
      721 cgattgtgat tggcttaacc agtgccttgc agacaatccc ttctcttgct ttattggcat
      781 tgatgatccc gctatttggc gtaggtaaat tacctgcgat tatcgcactc tttatttatt
      841 cattattgcc gattttacgt aatacgtaca ttgggatgaa aaatgtcgat tggaattatc
      901 gggatgtggc aaaaggcatg gggatgactg agttccaatc cattttttcc gttgaattgc
      961 ccattgctat gccaacgatc atggctggta ttcgtttagc tgccgtttac gtgattgcat
     1021 gggctacact tgcctcttat atcggcgctg gtggtttagg cgatttgatt tttagtggac
     1081 tgaataatta ccaaccagat ctcattttgg caggtacgat ccctgtaaca attttagcac
     1141 tattggctga ttggcttcta ggtctcttgg aacaccggct gacaccgatc gcacttagag
     1201 aggagaatga agaatgaaac gtatactaaa aatgaccatg gttcttttct ctcttcttat
     1261 acttgcgagt tgttccttcc ctggtcttgc cagcaataca gatgaagaca ccatttcgat
     1321 cacaggtgga atcacttcag aagcacagat cttagcaagt ctagttgccg gaatggttga
     1381 acattataca gataaaaata ccgcaatcat caacaatctg gctactacaa ctatcaacca
     1441 tcaagcgatg atgaacggag atgcttcaat ttcagcggct cgctacacag gaacagattt
     1501 aacgactaca ttgaaccttc ctcctgaaaa agatccgaaa aaagcgtttg ctaccgtgaa
     1561 agatgaattt gagaaaagat acggtcaaac gtggttcccg tcctatggtt ttgaaaatac
     1621 gtatgtcttt cttgttcgaa aagacaccgc acaaaaatac catctatcta aagtcagcga
     1681 tctgaaaaat gtagcggatg aattagtagc tggtgtagat acttcttgga tcaatcgtaa
     1741 aggagacggt tatgacggct tccaagaaac ttatggcttc tccttcaatt cgatattacc
     1801 tatgcagatt ggacttgttt atgacgcagt cgaagcagga aaaatggata ttgttcttgg
     1861 ctactctacg gatggacgga tcgccagtta tgatctagtc atgttggaag atgatcgtca
     1921 attcttccca ccatatgatg ctgctccagt tgtagacaac aagatattag ctgatacgcc
     1981 tcatttaaaa gaagccttaa ataagttagg tcataccatc agtacggaaa aaatgcagga
     2041 attgaactac gaagcagata ataatctagt ggaaccatca gtagtagcac aacgtttctt
     2101 acaagaaaac cactattttg aagggaagtg aagcaattgg ataaaatgaa tgtctttcaa
     2161 caatttttct attatttcca ggaaaatggc tcctatatct ttgcacaatt tatccgtcac
     2221 ttcctgattt ctatctatgg tgtcctcttt gcagcagttg tcgggattcc ggttgggatc
     2281 atgatttcta ggagacgtaa attagcaaac tgggtgattc gtttggcgaa tatcatccag
     2341 acgatccctt ctctagccat gatctccatt ttaatcattg gattaggcct gggagtcaat
     2401 gtcgtgattg ttactgtatt tttgtattcc ctcttaccga tcatcaagaa tacgtatacc
     2461 gggatgatcc aagtagacaa aaacatcctt gatgtcggca aaggcatggg gatgactgct
     2521 agacaacgac tattcatggt agagttacca ctctctgttt ctgttatcat ggcaggcata
     2581 agaaacgcgt tagttgttgc catcgggata accgcgatcg gtgcattcgt cggtgctggt
     2641 ggtcttggag atatcattat ccgaggaacc aatgcaacag agggcacatc gattatttta
     2701 gcaggtgcat tgccaactgc attaatggcg atcatcacgg actggctttt aggtattttg
     2761 gaaagacggc tagatccagc cagccgtaca tcacgctgat gttattgtaa aaaacaaaag
     2821 cttctgcgac catttgttgg tcgcaaaggc ttttttagtt ctgtcatttt taaggcaata
     2881 atccactctg attcttccct ccttatgggc aaagagttgc ttttcttagc tatttatcca
     2941 ttccgtatac tccaacttca tactgccaac gggttcatat ctgcatccac cgactaagtt
     3001 tttttcttat ccgctaaggc attttgccaa tccattttcc catcactcgt catggaattc
     3061 ataccacatg atctctaaat actcgtctgc ttgttctttg aattgggcat caattcttac
     3121 atcctttggc gtggctttca tttaagcctt ttccatcagt cctcgattgt tcgatgcctt
     3181 cagctgcatc atcaaaactg gtgactgccg tatcggtaac ttcgatcatc ttttatacaa
     3241 tcgggaactt gccatcctca tccttggcta aaaacatatc tagccattcc agcttctcgc
     3301 catgggaggt ttgcggttcc taaaaccggt acacgattct tatggactgc atccgtcgca
     3361 actagacttg gcgatacgat gatccttcac cagaagagca cccccgtaaa ccaattgatc
     3421 gatatattgc caataagaaa agacattggc gtaaaagata tcgatccctc gtgatgcatt
     3481 gccgttgata ctgctattca tggccgaaag cgccacgact ttaacttctt ccgtttgagt
     3541 gacattcatg ttcggcaatg tcgctttgga tacccgctct gctaaaggaa cgacactggt
     3601 attgtatttc gtatctgtat cttttccaaa agaccatgcc aacgaatcct ctgggaacca
     3661 ataagacgac tccggttgat tgtccattgc ttttttcaac atacttttgg ctgtttctcg
     3721 ataaacgaca tttccaattg tcttcgcctc actttggcga taatcgatgg tcgttgccac
     3781 tgccaacact aacaacgatg ctccaatttt actgattttc cttgtcacac ttcttcctcc
     3841 ttgttttaca taaacccgtc aacattccat tcctaaactc aaacaatgac ccttcaaagg
     3901 tggagatata ggaacaaatt aaagaaatca tgcaataaat ccaagaaggt tggttttaga
     3961 acaaaaaaag agtctccttt ttggggagac tctttgttaa ctatctaaaa aggttggctc
     4021 ttctcacttc actcataatg tgtccaggca gaataaattt ctacaacttt attttcctca
     4081 tcaactttgt aaaccactcg atgctgtcta ttcagcctgc gtgagtatct gccttcatgt
     4141 gtaggtctca gcttttcaaa agactgcgtg ggcatatatg gatcttcctt caatgtctga
     4201 atcacttctt caaattgttt ctttaaattc gtttgcttga tttttcttaa ctccactttc
     4261 gcagagtttt tgattgcgac tgtatagtta ctcatcaaag agcttcccaa tcaatatcat
     4321 cgatattcgt aaagctactg tcgtcttttt cgcggtctcg tactttatct aaagtacctg
     4381 tttgctcaag aaaaagggtt tcttgaatcg ctctccagtc ttccagccca atcaatacag
     4441 cattgtttcc actacgatca ctaataatct cgatttcagt atgattttca tttacctctt
     4501 tcaataactg ataaaaattt ttacgagcag tgctaggatt catcgttgta ttagccattg
     4561 tctctcctcc tttttctgat ataattatag cgtacttgat taagtacgtc aaaaaaatac
     4621 aataaagcac ttaaattcag caaacttttc ctctttttta catagagaaa aagacccctt
     4681 tttagggagg atctttgtcc acgctcactt cttactcctt tacgactagc ggtagccaaa
     4741 cgtaaagtaa ttggtaacaa cgtatcatct ttagcaaagg tcgaatccaa agcctgtgag
     4801 tctatgcaac aacaccaata cacgaaggtt cctcgttgca gtgtgacttg attgatatct
     4861 tgaataacct gaggatacgc acgaaagatt tgtaacggtt attcaaaact gattttggcc
     4921 gtcaagtctt ctactgcctc aaaaatgatt gcctctttcg tctcctgtca ttcatgttca
     4981 ctatcgattt gatacttgct tagaccgttg ggtttgtgaa tcaccaatta aaaatggcac
     5041 tgagttatgg taacaaaaaa tggtcacttg acgaggctga gattcctact tatgaagaca
     5101 catggcactt aagagtcgag gtaaaggaag aagctgaaaa tataggaggc tgtacattat
     5161 ttggcaaagg attcggaaat tatgatcaag acatcaaaat caaaatgttt tacagctaaa
     5221 taggaagaat aataacattt catacgctgt tcccatcttt aatggcttat agagggcacc
     5281 tttagctgag aataagacaa aacagaccct ctagcttcaa ttaagagcta gagggtctgt
     5341 ttttgatttt aaaacttggt ttatttcttc aaatggtagc tataggtgct gacaacgata
     5401 ttttcacgcc aagacaatcg caatcttaac cgcaaacttg tttggttatg gagaatattc
     5461 tgccagcgtc tgtttggtac aaattgagga atcaacacag tagttgtata gttttgtttc
     5521 gctgcatttt tacttacgat atctacataa cggataattg gattttcaat cgagcgataa
     5581 gaagagtgga cgattgaaaa acggacatct gggaaatgct ttttaaattc tgcttcgatt
     5641 tctttttctt tttcgacatc ttcgtctagc gaaacatgca tcgcaacgac ataatcaccg
     5701 atcgaacgtg cgtaattcaa cgcaccgata tttacccgtg tcacattccc gactaataca
     5761 agaacggtat tcccgtcata atcatgtagt tttgcatcat tttctaaacg aagctgttct
     5821 gctacttttt tataatgatc atggatctta taaaaaatga acataacgat tggcataatg
     5881 atgaagaaag gccaaatgtc ccctaaccga tagacaaaca aaatcgcaat gattgcatat
     5941 gagatgaacg cacccgtaat attggcaatc gatttgctta accatctttt tccttctttt
     6001 ttccatttga cgaccatccc tgtttgagat aaagcaaatg gaatgaacac gccgatagag
     6061 tataacggaa tcaagcgttc tgttgagcca tggaaaataa acagcaatac gatcgaacct
     6121 agcgctagtg tgataatccc attggaatag cctagtcgat ccccacgatc ttgatacatg
     6181 tgaggcatga atttatcttt tgccagattg tatgcaagaa ctggaaaagc agaaaaaccg
     6241 gtgttagcag caactgctaa aatcagcgct gtagcaaatt gaaggacgta atacaaaata
     6301 ccatgtccaa agacagcttt accaatttga gacaaaacag tgacttcttt ttcaggaacg
     6361 atcccatacc aatagttgat aaatgtgatc cccacgaaga agaaacctaa gatcaatgcc
     6421 atcatcgtca atgtagcagc ggcatttttt gctcttggct tcttaaagaa tggtacagca
     6481 ttactaatcg cctccacccc agttaaagag gaagaaccag aagaaaatgc tcgtaaaatc
     6541 aaagcgatag aaacacccgg cacagccgct cctggaagtg cagtagcttg caatggcaca
     6601 gcacctgtca cgatattata taaaccaaca acgatcagta acgagatcac aaggataaat
     6661 gtgtacaccg gaaataatag gaacgatgca gattccctca gcccacgaag attcagcatc
     6721 atcagtagca aaacgattgt cacagaaata gcgacttgat gaccgtagag tgctggcacc
     6781 gctgatgtga tcgcttcagc acctgctgag acagatactg ctactgtcaa catgtagtcg
     6841 atcaataaag agccaccgga aatcaagcca gcattctttc caagattctc actgctgacg
     6901 acatatgctc ccccgccatg aggataagca tggatgattt gacgatatga tagcgttaat
     6961 gaaatcaata aaataataac aaaagcggca atgggtagcg aataccagat ggctgcagca
     7021 gacaaagcga ctaaaacgac aacgatttgt tccgtaccat atgcaataga tgataacgca
     7081 tcagacgaca ataatgccaa agcagcaaat cgggttaatt tgtgctcatc attttcagca
     7141 gattttaaag gcttacctac taacaacctt tttaagtaat ccaatttcta aactccttta
     7201 cacacaattt tacttcaagt tttatagtcg aaaatttata gtaaacaaga tgttatagta
     7261 cgctcactga ccttaaaagt caataaactt taagaaaata attggaaaaa aacagaaaaa
     7321 tatcaagcgc tttttcaaac gctttaatac agcaaaaatc taacattttt ttatgggctt
     7381 tttctttgaa ttctataata aaaggataga acttgactta gaaaatcaag ttctatcctt
     7441 tttgatatct taacttttgg aagagagatg taaggctgct ttctacccat cattcttact
     7501 actcgaagca tagcgcagtt gtcacaacct cttgataaac ggtgtttaaa agcttgcatc
     7561 tgcggtaata agctcaacca aattaaaaac ataagaagct gtttttattt ggtcgttctt
     7621 attacttgat gcagagcagc ttttttacaa cctcttggta cacggtgttc aatcagctga
     7681 ccctcggtat tagctcaaaa aaacggcaaa atatgaggaa ctatttttcc atttttttct
     7741 ctaatactca ggtcaaaaca ctgatttcac aacctctttt tttaatgaaa aatatggctc
     7801 tcatgcgccg cttctttgaa tttcgtcatt ttttcttcga tgaacggata gattgccgtt
     7861 cctacgattc caaagacaac aaacaaaccg atcatgatcc agattgcttt cgtagcattt
     7921 ggccaataaa ttcctcctgc agattcccgt aacaagttta ccgcatgagt aaatggcaag
     7981 aacggattga tcatttggaa gaatttccct gagacttgga tcggatagtt cccgcctccg
     8041 ccagagatcg acagtactaa gatgataata gcgatccctt taccgacatt atcgaataat
     8101 gcagccaaga catagacgat catcatgaac gctaaggcga tcaagacagc aaatgacacg
     8161 ctgtagaccg gattttggac atctactcct agtaagaaaa tattccctaa tgtaacgatc
     8221 aagctttgcg caatcgccat tgtcaaaaat gtcagcatac gagcaacgaa ttgttctcgt
     8281 ttcgtaaaat tgtttcggtc tttctttcct aaatagtatt ctgtcgtagc aacacttgaa
     8341 agaagaacag cgccgaccca cagacatagt gcagtataaa acggggtgct agctgaaccg
     8401 ttatttgcga ttggataaag cgcattggtt tgtagctcaa caggttgtgt aaagaagtca
     8461 ctttcttttg ttgcgtctag tttcaataat ttgatgactt cgcctagatc gacttcttgt
     8521 tcgccttttc ggatcgcgtc tgctgctttt tggataccag ctttgatatt tggccagtca
     8581 ttgttgatca agtccgcagc agcgttcaca gctgtttcga cttctggcat tttttcattt
     8641 actgttgtca atgtaccggt gatttcattt tttagtgctg gccaatcatt ttggataaaa
     8701 tcagcggcca atcctaattt ttgctgaatg atcggtaatt cattgttgta taggtctgcc
     8761 ccttcattga tgccattgac gatggtatcc atatttccat tcagcattgt attggcatca
     8821 tggatttctt gtccaattgc aggcatttct ttttgatatt tttctaaaat tgccactgca
     8881 ttcgttacag ttgctttcgt tgagctgaga agcgaatcaa agtcgatctg gtccgctttg
     8941 ctcagtgcgc cttgtgcagt cccaatcgta tcgatgactt ggtctagtag agaagtgaca
     9001 gtggaactga tttgacctgt attgatacca gcaatgatgc cattgatatt attaacaacg
     9061 gcatcaattt gatctagcaa ttcatcaata gccttcgtgt cttcattttg aacagctgtg
     9121 ttcaaagcag ataggcggtt ttgcagattg cttagcaagg gttttaattg atttagctga
     9181 tcaataattg gctgtaattt cgtatttcca gcacttgttt gcaatttagt caggaactcg
     9241 accagtttat cgattgcatt ttgttgttga gatattccgt caataaagcc gttcaataca
     9301 ttgctgatgt ttttcttttc atcatcagtc agcttaccat cttcaatagc tgttcttaca
     9361 gtatctatta acgaacctgt cgttgttgcc acttgtccaa ttgacttcaa tgtaacatct
     9421 acactgtttg tgatgcttgg tatcgcatct ttcagctgag aggcacctga ttttgtttgg
     9481 tttgctagat cacttgcctg attttctaaa tttttcacat ctggcaagat atcttgtact
     9541 tgttggatga tcgtcaagcc ttgttttgct tcatcgattc cttggttcat tgtctcttgg
     9601 atcgaagcaa aatcgccgtc gatctctgct agttgcttac cggcattttg gatctctggg
     9661 attttttctt gcaaatcaag gatgattttt gcttgatctt tcaactcagg cattttgtca
     9721 ttcaatgcaa cgactttttc acccatctca tctactttag ggatgtaatc cacgaattca
     9781 tttgctttat tcagtttttc cttgatttca ggtagttgac tttgtaattc gaggacttgt
     9841 tttgtgtagc cgtcgatcgt gtccaaattt tcatctgttg ataaaatcat atctttaact
     9901 ttattgatac ttactaggtt cgtatcgatg tcgtaaccta tctcattgaa tactttcaat
     9961 aaagtcgaac tggctgtttt gataaattca tttgtgattt gcgattggat cgaacttgct
    10021 cctttatcgg tgattttcgg tgcaatcgca ttgatttttt catttaccgt atattcgatt
    10081 tttggtttct tgatatcacc actagtaaaa ctcagcagat cttctgagaa atcctttggc
    10141 aagtaaatac ctgcgtaata ctttccggaa cggactccgt cttctaattg ttcttttgaa
    10201 tcaacgaatt gccatcctaa ttgtttattt ttatgaagcg attcgatgac ttgctcccca
    10261 atggccactt ctttaccttg aaactctgct ggcttgtctg cactgtaaac agcaattggc
    10321 agctctccag tatttccata tggatcccat aatgctttga tgttaaacca cgcatatagc
    10381 gaagggatga tcatgatcgc gatgatcaga agtgttgcaa tcgggttttt gaaaatccgt
    10441 ttccagtcaa gcaaatataa tcgaagcgta tttttgattg actgcatagt tctccccctt
    10501 cttctttttt cagctgaatt actttaccat gtatttcata cttttttcaa tcggcttttt
    10561 tcaaaaaagt cgaatttttg gacatatcac ggcaattgtc tcattgtaat ctcttacata
    10621 ttgagaaata attaaggatt acagccttta ctttatcatg aaataaaagg gaaagataat
    10681 tttatgccaa agtttttatc tattatacgt atacgcaaaa aagctaaaac attttttgtc
    10741 tttgccccta caaaaatgtt tcagcttttt tcgtttttta ttcctgtatt tcttattttt
    10801 cgaatgacag gatgattttc ccagcaggag gatgtccttc aactagctga tgtgcttgga
    10861 tgacatgctt aagtgaagca gacagattca ttgaaataaa aacatgaaag gctccttttt
    10921 ggtaggcttt gattatgcca gcaaaggctt ctgcatctag atattccttt cttggaacaa
    10981 acgattcata aaagccttcc tttttttgcc gcaaatctag atctgggagg tcatttaatg
    11041 caacatacct gccgcctggt ttcatgatct ggatgccggt ttctcctttg atacttcctt
    11101 tcgtcgcatc gattacaagg tctgcctgat cagcaaattg cagacctgga tttgttttat
    11161 cataagcagc aaatgctgaa gctcctaatt tttttacctt ttcctcattt ttactggatg
    11221 cactggttaa gattcggatt cccttttcat ggagaagctg gatcagactt gacccgaccg
    11281 cacctgatgc tcctagtatc attacagtat ctgtcggctg gatttccgtc aaatggttga
    11341 ttagattata agccgtaatt cctggcgtga ccattccggc tgcttcttcc caactcattt
    11401 tatctggaat ttttgctact tttgctgatg gcaacacgac ttcttctccg taagtcccgc
    11461 cgactgcatg gacagctact cgatcaccta catgaacagt tgtgacatct gaaccaatct
    11521 ctgtcacaat accagcgcca tcattacctg gtacataagg gaatttcaat gttcgtatct
    11581 ctttcatttc tcctaaacgc aaggcaacat cataaggatt cacactgaat gcttttattt
    11641 ctacacgaac atgtccagaa ccgacttctc tgggatgagc atcgatttct tcaaaaacat
    11701 cttgtgcttc tccgtaaccg ttaattgcaa atcttcgcat ggtcaccatc tccctttttc
    11761 tttaagttta cgtttatgtc tttattttga caaaaaaaat gtcttttcgt tttggcgcat
    11821 gattcaaaac aaaatagttg tcttttttcg cgtaacgtgt taaattattt atctaaaagc
    11881 gtaaagatta cgatttacgc taataaaaaa taattggagg aatttgttga tggctaaaaa
    11941 atcaaagatt gccaaagcaa aaaaacagca agaaacgatt gaacgctatg ctgctttacg
    12001 ccaggaatta aaagcgcaaa aagattacga aggcttgcgt aaacttcctt tagatgctcg
    12061 tccagaacga ttgaaaaatc gtgatttaat cgatggacgc cctcgcggat acatgcgtaa
    12121 attcgggatg tcccgtataa aattccgtga attagcacat aaaggtttga ttccaggagt
    12181 aaaaaaagcc agctggtaat ccaagtctgg ctgtaatgta aaggaggagg gcgcatggac
    12241 cactccttgg atcatcaaaa aagatacgtt cgcttcttct agcagaaatg ctggtactag
    12301 aagcagacgt atcttttttt acgcacagct ggtccttttt tatatgtaaa ggctgcatgg
    12361 ttacttcgct atatttattt agtaacagga gtcagtgctt cgatacccac actaattttc
    12421 aatgctcggt caacttctgc cataatgggt cgatccaaat ggcagacctt ttctttcaat
    12481 cttgatttat cgatcgttct gatctgctcc aacaggataa cggagtctct ttctattcct
    12541 gttccagtag ctttgatccc aatgtgagtc ggaagcttag gtttagccat ttttgccgtt
    12601 atggccgcaa caatgatcgt cgggctaaaa tggttaccta gattattttg aataaccaaa
    12661 actgggcgtg ttccgccttg ctccgatccc acgactggag aaagatcagc aaaataaata
    12721 tctcctcttt ttaccatagg atcctcctta ttcttgatat tctcttggta tccgctgtcc
    12781 taatccgcaa gccacttcat agtggatcgt acctaattga tctgctatat cctgcatagt
    12841 gatttctttg tctgcatttt tgccgataag cgtcactttt gttccgacag gaaattcttg
    12901 aggcaatcgg atcatcagtt gatccataca tacacgccca atcgtttcac agtagttccc
    12961 ttctaccaat agagaaaaac cctgcatctt tcgtggccag ccatctgcat aaccgatcgg
    13021 tatcgttccg atccactctg cttcaggagt gatatatgtt tctccatagc cgattccttc
    13081 acctgctggg agttttttga cttgaatcaa ttcagaaacc agctcaagtg ctggctgcaa
    13141 tggataaact tccggtagtg cgtgcccaga gggattaagt ccgtacattg ctactccata
    13201 acgaatcata ttgccgattg tttcatcatg ccataaagcc gttgcactat tgctgacatg
    13261 tacatatcga ggaagttcgg gaagtttttt cagcacttct ataaagcgtt ctttttgcag
    13321 attccaatat gtatcatctg cctgatctgc tgtagaaaaa tgggtaaata aaccttccca
    13381 ttctaataca cgactttctt tgatgaatgc agctgcctct tttacttctt caggtgtaca
    13441 aaatccgata cgacccatcc cagtgtctgc ttttagatga atcgaaagag gcgtctctag
    13501 cttacttttc tctaaaacag cagctgctgc ttgcaaccat tcccgtgtac ctgcagttac
    13561 tgataaatca tgagcaacag ctacagtcag tgcgtcgtaa ggaaccatat tcaagataag
    13621 gatgggctga gtaaatccag cttctctcaa ctcgactcct tcatctaaat ttgaaacaca
    13681 aaagcccgaa gctccacctg caactgctgc ctcagctgtt tcaatagctc catgaccgta
    13741 tccgttcgct tttactactg caaacaattc ttttccttgc ggaagtcttg caacttcatt
    13801 tgctacattt tcagttatag cttttttatg tatcactgct ttcgttgggc ggtgccaagc
    13861 gacaaccatc gtttttcctt ctttctagtc ttccaaaata atttgtgcaa aagctgtttc
    13921 atttgtatga gtaatactga cccatacatt gccttcatga ggtgaacgcg tcacaacagg
    13981 ctgaccattt tcatttttta aaatctcgac atcttgaaag gtaacttttc cgatcccagt
    14041 tccccaagct ttagagaaag cctctttgca agcgtaacgc ccgcctaaaa attctacttg
    14101 gcgatgaaaa ggcaaggact ggaatagttt catttcatca gaggtcaaga ttcgtgcaat
    14161 gaattttggt ttttcttcga tcagccgagt gatcctagga agttcgactg catcgatccc
    14221 aattcctttt atcatatgct tttctctttt caataaattt agaacactct cattctacca
    14281 aattataacc attttgccac aaataagtcc acaaataaca aaaatgaaag tttctcttaa
    14341 aaaagagaaa ctttcatttt atgtttaatc gttatttgaa cggattacaa atccgcgttt
    14401 tttatcattg tgacgtttac cgccatcttt ttggctgtta ttatttttgc tataaccgcc
    14461 ttttgatttg tttccacgat aattaccgcc gtcacgacga ttacggttgt ttccgccacc
    14521 acgtttgcca tttttattgt atcctttttt ctgcattggc aatgggcgtt ctggtgtgat
    14581 cttcactggc actgcatcag ctggatcttt tgctgtcgtt tttagcaaaa gtgcaactaa
    14641 atcttgtgca gaatattctt ctaataattt atctgctgtt tgcaggtatt tatctagacc
    14701 attttctgca agttttgttt cgatttgttc aactgcagca cctaattgac ctttgaatgc
    14761 ttctttttcg gttggtggac gtaaagtcgt catccgtttt ttcgtcaagt tttcaatcac
    14821 atgcaagtag tccatttcat ttggtgtaac gaaagtcaca gacataccgc cttttccggc
    14881 acggcctgta cgtccgatac ggtgaacgta gctttctgga tcttgaggga tatcatagtt
    14941 gtacacatga gtgacacctg aaatatctaa tccacgtgca gcaacgtctg tcgctacaag
    15001 gatatctaaa tgaccgctct taaatgaacg caatacgctc attcgttttt gttgagacaa
    15061 atcgccatgg attccttctg cacggtaacc gcgtgcttct aatccgcgtg ccaattcgtc
    15121 tacacggcgt tttgtacgtc cgaagacgat tgttaattca ggtgtttgaa catcaaacaa
    15181 gcgagtcatg atatcgaatt tttcgtattc ttttgcgcgg acatagtatt gatcgatcaa
    15241 gtcagctgtc atttctttcg ctttgatctt cacatgatgt ggatttttca tgaatttaac
    15301 gccaatattc ttgatagctg gcggcatcgt tgctgagaaa agtaatgttt gtctttgatc
    15361 aggaacttgt gaaatgattt tttcgatatc ttccaagaag cccatattca acatttcatc
    15421 tgcttcatcc aaaactaatg tttgaacggt tccaagtttc aatgtgtggc ggttaatgtg
    15481 gtcaagcata cgtcctggtg tacccacaac gatatgtgga cgatctttca agccacggat
    15541 ctgacggcca atatctgctc cgccgtaaac ggcttgtaca cgtacttttt tgtcgcgccc
    15601 taaacgatat aattcttctt gtgtttggat agctaattca cgtgttggtg cgataactaa
    15661 accttgtaat tcgtgacgat ctggatcgat tttttctaac attggtaatc caaatgcagc
    15721 tgttttccct gtacctgtct gtgcttgtcc aataacgtct tttccagcta atgctagtgg
    15781 aatcgtttct gcttggatag gcgttgcttc ttcaaaacca gcgcgttcga ctgatttcaa
    15841 caattctggt gataattcta gttctttaaa tttcaaatga atcctcctat atggttgtta
    15901 actgaggatg tagctttttt gctaccccgt cgatttgttc ggtcaaagtg tattgtttct
    15961 ttttgacagt ggccacgcac gtttttatcc attcttagcc cctgtggcac caccgaaaaa
    16021 tcactttgcg aagtttaggc attagaaaag ccaaacgggt cgcgttcagc tttatcatta
    16081 ttatgacatc tggcttcaac aagttgtttc tatggcaaaa ccagtccaat ttctcttcat
    16141 ctttcggcaa taggttattc taacatagtt tttcgttttc tgcaagttta cagattttta
    16201 tttcatttgc tgaagttgtt ctaccacttc aaataagccc atgctgttgc tgccttttag
    16261 cataatacta tctgttgctg caagattttg tttgatagca tcaatcaatt tattcttttc
    16321 tttttcaaaa tagaacacag gtagttgggg gtatttttgg ttcaattctt cttttagtgc
    16381 atgcatttgt tccccataaa ggaaaatcat ggcgaatttc tcaggatcga tatgttcact
    16441 catttgcgca tgcatattta aagactcttt ccctaattcc agcatatctg ctaacacagc
    16501 gattctgcgt ccttttgttg gcagattttt aaaagtatct aataccagtc ccatggctgt
    16561 tggatttgca ttgtagacat cgctcaaaat agctgcacca tttcctgccg ttagccattc
    16621 ggttctgttt tgagtgatag aaacatgggc gagcccttgg cgtatctcag gtatggacag
    16681 tccaaagaag cgcccgatcg tatacgcaat caaagcattc gttacattat aacttccagg
    16741 cagcgggatc gtaaatgttt ctccttctac tacaaaatcg gtttgtgctt ttccttttgc
    16801 tgtcacttcc gcatgaacat cgccatttcc aataccgaat gttgtgactg tttgtactaa
    16861 tgttgccgtt aaaggtgtca gcaacggttc atctgcgggc acaacgagta atccgtctga
    16921 tacaagtccg tcagtgattt ccattttggc tttagcgatt ccttctcgcg acccaagatt
    16981 ttctatgtgt gcttcaccga tcattgtgat tgctgcagct tttggttgag ccataagtga
    17041 aagttccgtg atttcattgg cgtgatccat gcccatttcc aaaacgatct tttctgtatc
    17101 ttggggcatg tgcaaaatcg tgtaaggaag accaatatta ttgttgtaat ttccttgcgt
    17161 cttatatgtt ttgtattttt cagacaagac agacgcggtt agatctttcg tggtggtttt
    17221 accattgctt cctgtaattg caacgacttc tgcgcctact ttttccaagt aataggttgc
    17281 caattgctgc atggctttca aaggatctgc tacaggaata actggaaaat tttttggagc
    17341 ttgttcaaca ggcaagctcc aaaatgaagc agatgctccg tttgtgatcg cttgctggat
    17401 aaattcatgt ccatctcgcg taccagcaag aggaacgaat aaacttcctt cggttatctt
    17461 ccggctgtca aattcgacat tggtaatctt tgtcagtgca gagcattcgc tgcccacggc
    17521 ttgtgcaatt tcttgtattg ttagattcat tgagatctct cctaaaaaag gttgtgaaaa
    17581 aagcgtttgg cctaaacggc gggttcgcat gactctcact tccaagtaaa tttctctatt
    17641 cgtatttaga agctagaatg aacgcggtta cgcaatcact ccagcctctt ctttatttct
    17701 ctttattcat ttttttcaaa aaaagattga cgctgatggt atcgattcat tcctaactgg
    17761 atcagttctt caatcaaatc accgtatttc aagcccatat tttcccataa gagtgggtac
    17821 atactgaact ccgtaaatcc tggcatagag tttaattcat tcaggaataa ttcattttta
    17881 tttgtcaaaa agaaatcgca ccggctcaat ccgcttccac ctaacatcgt gtaagctaac
    17941 ttcgcgtact cttgcgcttt ttgataaact tcttctggca cttcggctgg aatctgcatt
    18001 tcgattttat tattgatata ttttgcttca taatcataga atgctacgtc ttttacgact
    18061 tcaccaggca aagtcgtccg aacgtcttca tttcctaata cagcaacttc gatttcgcgc
    18121 gcttcaattc cttgttcaac gattgctcga gaatcatact gataggctgt tgctaaagca
    18181 ttttgcagct cttctcggtt ttctgctttt gtaatgccga cactagaacc catattcgcc
    18241 ggtttgacaa acatcggata aagcaaagaa ccttcacatt gatcaaatac ttttttagga
    18301 ttttctttcc attgattctt aagtactggt acataaggaa cttgcggcac accagcagct
    18361 tgtaaaatat acttggtcat gattttatcc atggcacatg cactggtcaa tacgcctgcg
    18421 ccgacataag gcatattcaa tgtctctaag aagccttgga tcgttccatc ttccccgttt
    18481 ggcccatgta aaactggaaa aacgatggct ccttcttctt tgatttcgcc cggattgatc
    18541 acttttcctg taaagccttc ctctgtctgt ccacttgggt cccatgaaag atgcaagaca
    18601 tctttgctgg caggtttttc tgttagtaat ggacctttga cccattgtcc ttcttttgta
    18661 ataaatacga gttgaacttg gtaataatta taataaatgg catttaaaac tgaaaatgcg
    18721 gaaagaatgg acacttcatg ctctgcgctg cgtccgccat atagtaaagt aatcttcaaa
    18781 agattgtcct cctgtattct aaatcgttca gtgatttact ctcatatttt agcacaaaac
    18841 aaaaataaac gaataactta tttataaaaa aacgagccag cttctaaaag aacgagcgtc
    18901 atttattttt tgtcagctag attatttgtc ccgtttttta taaaaagtta tgataaagaa
    18961 aaggagggat gatgatggcg caaacaaatc cacgcagccg cttggcagaa atcattcgag
    19021 tgttcatcaa ttacaatgta gtgccaaact ttgtacagca aaaaaatccc gaacaggtaa
    19081 aaaaagcctt tgaagaacta ggccccacct tcatcaagat aggacagatg ctttctgttc
    19141 gagaagattt gctttcttct gccttcactc aaacattcaa aacattacaa gatagtgtac
    19201 ctagcgacac attttcaacg gtcaaaaaga cgatcgaaac agaactttct ctttcattat
    19261 cagatatatt cgatgatttt tcaaaatcgc cttttgcctc tgcttctatg gggcaggctc
    19321 atcgtgccaa gctgaagaac ggtgacgcgg tagtcgttaa gatccaacac cctaacatcg
    19381 ccgaagagat ccgacttgat cttcaactat ttgaacgagc gatccctttg atcaaataca
    19441 ttcctgaaac tagcgtagtt gatctaaaag gggtactcca agaagtaaaa cgttccttga
    19501 tcaatgaaat ggacttctta aaagaaagtc aaaatggcga acaattctat caaaagaaca
    19561 atggctggaa agagatccgc agccccaaga tttatgacgc tttttgttcg aaaaaagtga
    19621 tcgtgatgga agaaatgtct ggtaaaaact tgaatcattt aatgaacgcc gaaaacaaaa
    19681 ctgaaacttt tatcactgga attcaaaaca agcagctgaa acaagaagtt gcaaagcttt
    19741 tagttgagaa ctttatgaaa caggtgtttg atgatggttt tttccatgct gatcctcatc
    19801 cagggaatct gctattccat gtactaacaa aagaagaaca gacacaagct agccgaaaaa
    19861 ctgaaacagt ccatgaaaaa gagttcggtt cctttgcttt tcgagcctcc acttctgcag
    19921 aagaccctgt tgcgccatat accatcaact acatcgattt tggtatgatg gggcatcttt
    19981 ctgcaggact taggcaaaaa ctcacacaag ccgttttagc gctgtatacg aaagatgctt
    20041 atcgaatcga aaaagcggtc cttcgacttt gtcagcaaga aggctcgttt gatgaaagtc
    20101 ggttccacca agaactgaca agttttcttg aacagtatta tgattctcct attgatgaaa
    20161 tcaacttgca agaagtattc acacatgtcg tgacgatttg tcatcaaaat aatctgcagt
    20221 tcgatcgtga tatcacgctt ttgctgaaag catttgggac attagaaggg gtgatccgcg
    20281 tcctcgatcc tgaagtttcc ctcatggaag tcgcttcgcc ttttgctcaa cattattttc
    20341 tcactcatct ggatgtagaa gatacattga aacaaagcgg attagactta ttggaaggga
    20401 tgaaggctgc gcctaagatc cctcaacagc tccaccatct attagaaatg tggacttcgg
    20461 gacaaggaaa agtcaatttg gaattgaaaa agcaagacaa attattgagc aggatcgaaa
    20521 gtatgatcaa tcggcttgtt ttcggtatga ttttagctgc attgatcgta gggtcctccc
    20581 tgcttgtcca agcagcacct gtagaaaacg cagaggtcgt ttccttatta gggatattta
    20641 cgtatgctat tgccgcattc gtcattattt ttttggcaat cgatgcattg atccaaatgt
    20701 ataagaagag gaaaaagtag aaaaaggttg tgacagaaag aatcagcttc aagaaataag
    20761 aaggggtttt acataaattg tttctcaaat ttttgtgaaa attcggctta tttttcgaag
    20821 aggctacttc tgaaacaccg agaataaaaa atgtgaaaaa gctattctgc acccagtaat
    20881 aagaacaatc aaaaagggaa catggaacac atttatcctg tttccctgtt ccctttttga
    20941 tgtattcgag cataaataaa ataccttcgt tacctactat cttctgtact tggtaaacct
    21001 tagtcaattg ccttttttaa cgcttgacga aaagacatat gatctttctc cgtaaagggt
    21061 tttggaccct ttgtccttat gccagctttt cttaactttc cactatgata acgttgttct
    21121 agaagcgtgc cgatattcgc ttcgtcaaat tcttttccag agtgatggaa cactcgcaca
    21181 cccttcggca atacaagtga agctaaacca taatcttgcg tgatcaaaaa gtcattcttc
    21241 ttaaccatac cgacgatttt ataatccgca ctatcagctc cgcggtctac gtagacgatt
    21301 tggacatgat tagcgtattc tttggtcgta taatggtcca cactggtcac gataaccacg
    21361 tcaagaccat aggattctcc taattttatg acatcttctt ttactggaga accatctcca
    21421 tcaatgaata gcctcattct ttttcgcctt cttccataaa tgataaacag ttactaatcc
    21481 gctcagtaaa agaccaacat tgatccattt tgccaagata agcagttgta cactttctat
    21541 cggcactgat tcatggttca gcgtgatcaa taatagatgg attggctctc ccatttcttt
    21601 tgctaaaaca aacaaaagcg tcatcaataa aaactggtgg atcacactcc ctttattttg
    21661 agtagtatac ttgacaacga tccggcgatc cattggaata gctgtatcag tttgataata
    21721 ttccttattt agccagctgc ctgttactac gtgccagaaa ctaagcagaa agacacctat
    21781 cgcaaaacca tttggaatca agaggaccaa taaagaagaa ctcagtccaa gcaattgcat
    21841 agccaatgga gaccatgtta aacgtttcaa aatccatggt ccgactattt ttgctgcaat
    21901 caagcctgct gcataaggca aatacataaa aatcgaaagt ttttctaatc cgtacagtat
    21961 gccaacataa aaactgctaa ataaaaaaag gaaattccct agcattccat ttagaaaagt
    22021 aaacagattt agccagcttg gcaacttcca ttccttcttc tggtgtccta aaacaaacac
    22081 gaacaagatg aacagcagca agaaaccata aatagcaaga tcaaaaagcc tttcatcgaa
    22141 taacaatcgg gcatttctca aaagaaacaa taagccaaag aatatcaaaa ataaaacaag
    22201 ctctcgcgta gctaccagat ttcttttgat gtctttgaaa tccagttcgt aacgcggata
    22261 atgactaacc gtatggtagg ccatgacgta aaaaagtgta taaatagtaa agcttgctgc
    22321 aatctgagtc ggtgcaggca actcaatcgc ttgatacagg agaaatagcc agatagctgc
    22381 aaataagtac tttttcccat ccatattgat aaaaccttgc gtcttttcgt gaaaattgac
    22441 cgtggtatta gcaggtacaa gccatgctgc actcagccct agcaaaacac ttgaaaaata
    22501 aaataaagga aaataaaata cgcctaatat tccaagcaat gaaccagcac caccaatcag
    22561 cagagcgatc atcagcaacg tgtaactatc tagaccaaat cgtagactgt tgactaaaaa
    22621 tagtccagtc atccgaaagg cataaaacag cgtaaatggc aaaatcgtca gccaattatg
    22681 cgagtctgtt agtcccaaaa ataaaagata aggaataaaa ataaccgtgt tacttaagat
    22741 aaagggcgtt gtttgtgtaa aattacgccc aaatcgtttg agtttttcga acatgacaat
    22801 ggctccttaa acagtcttat aactaatctg ctcttcgatt ttagcattaa aggggaaata
    22861 aaccaatttt acagaatata ttcttgtaaa aaaaaataca gaaagaagca taagcttctt
    22921 tctgcatttt tacggtactt gattactcaa gcagacaagc ccttctccac aaaagtcttg
    22981 cccgacaccc ctgcatccgg caggtgataa agatagaaat caattatcct gtgcctccaa
    23041 aatcaattag gagctctgta aaccagagtc cttctcgacc cgtcgcataa atttacttta
    23101 acacagttcc tatgtttatg cgagagcttt tttcatttta taatcgacca tttgaaatcc
    23161 ttgaccgata tctgaaataa gttcttctgt aatctcaaat ccttcatgct tataaacctc
    23221 gattgcttga tgattcccct gattcactcg caaaaagatc tctctttcct ttgtttgcgc
    23281 agcaagttct tcataccagc gaaaaactga agaagtcaat ccttgaccac gtactttatt
    23341 tagcaaatat aatttactta aataaatttt tccatttatc tcttcataag cagtgtaacc
    23401 gacagtcttt tcttcgcttt ttaataaaaa gtaggacaca ccttctgtca gttctttttg
    23461 aatctgtttt tttgactgat aagttttcag catgtaatcc acttgttttt gaccaatgat
    23521 cggcacaaaa gcttccggcc atacttcttg tatgactgcc atcagctcat ccagttcatt
    23581 ttctgttact tttatttttt ccatacaccc acgtcctttt ttacattata aatgaccttg
    23641 cgcttgatgg aataaaaaga gcatgatcat gctatacaca cccaccgacc atggtttcaa
    23701 gaaaatcaca atctgcataa attccctaaa agataatttc gtcaaaccag ctactagaca
    23761 gatcaagtcg tctggcgcaa agggaagcag caaggtaaca actagtactt ttttaatatc
    23821 tttcgttttt cttgtcagca attcatcaaa tttctgatac ttttttggcg ataaaataag
    23881 ctggacaaag gctacgccat agtaacggac aagcaaaaat ccgattgctt ccccaatcac
    23941 taggccaata caactatata aaagcccaaa tccattgcca aacatcagca tgcccgctac
    24001 tgaggagatc cctcccggca aaataggaat gatcacttgg atcacttgca acagaacaaa
    24061 tatcatcact gcatacttgc caaattgctg gataaacgct tgcaaagacg tgctcgatcg
    24121 aaaaatccca tgatgataag cataaagaat caacacaaag aaaaaaaaca gaccaataat
    24181 gggcatgatc tgaagacatt tttgtaaaac tgatcctttt ttagacatct atattcccca
    24241 catctttttt catttattaa aactgcctcc t
//
LOCUS       DAFEKH010000041        23827 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.042, whole genome shotgun sequence.
ACCESSION   DAFEKH010000041
VERSION     DAFEKH010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23827
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.042"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(53..787)
                     /locus_tag="LP386_001892"
     CDS             complement(53..787)
                     /locus_tag="LP386_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBL1919127.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1114..1524
                     /locus_tag="LP386_001893"
     CDS             1114..1524
                     /locus_tag="LP386_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HBL1919128.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1517..2218
                     /locus_tag="LP386_001894"
     CDS             1517..2218
                     /locus_tag="LP386_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HBL1919129.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2218..3804
                     /locus_tag="LP386_001895"
     CDS             2218..3804
                     /locus_tag="LP386_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1919130.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3823..4044
                     /locus_tag="LP386_001896"
     CDS             3823..4044
                     /locus_tag="LP386_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HBL1919131.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4041..4802
                     /locus_tag="LP386_001897"
     CDS             4041..4802
                     /locus_tag="LP386_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HBL1919132.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5182..5691
                     /locus_tag="LP386_001898"
     CDS             5182..5691
                     /locus_tag="LP386_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBL1919133.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5766..6305)
                     /locus_tag="LP386_001899"
     CDS             complement(5766..6305)
                     /locus_tag="LP386_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HBL1919134.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="LP386_001900"
     CDS             complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="LP386_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HBL1919135.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7318..8169
                     /locus_tag="LP386_001901"
     CDS             7318..8169
                     /locus_tag="LP386_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBL1919136.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8197..8832
                     /locus_tag="LP386_001902"
     CDS             8197..8832
                     /locus_tag="LP386_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBL1919137.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8852..9625
                     /locus_tag="LP386_001903"
     CDS             8852..9625
                     /locus_tag="LP386_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL1919138.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10033..10830
                     /locus_tag="LP386_001904"
     CDS             10033..10830
                     /locus_tag="LP386_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HBL1919139.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10808..11221
                     /locus_tag="LP386_001905"
     CDS             10808..11221
                     /locus_tag="LP386_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBL1919140.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11205..13850
                     /gene="mutS"
                     /locus_tag="LP386_001906"
     CDS             11205..13850
                     /gene="mutS"
                     /locus_tag="LP386_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBL1919141.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13868..15976
                     /gene="mutL"
                     /locus_tag="LP386_001907"
     CDS             13868..15976
                     /gene="mutL"
                     /locus_tag="LP386_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HBL1919142.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15998..16558
                     /gene="maf"
                     /locus_tag="LP386_001908"
     CDS             15998..16558
                     /gene="maf"
                     /locus_tag="LP386_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HBL1919143.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16643..18631)
                     /gene="treP"
                     /locus_tag="LP386_001909"
     CDS             complement(16643..18631)
                     /gene="treP"
                     /locus_tag="LP386_001909"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HBL1919144.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18854..19567
                     /gene="treR"
                     /locus_tag="LP386_001910"
     CDS             18854..19567
                     /gene="treR"
                     /locus_tag="LP386_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HBL1919145.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19644..20090
                     /gene="msrB"
                     /locus_tag="LP386_001911"
     CDS             19644..20090
                     /gene="msrB"
                     /locus_tag="LP386_001911"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HBL1919146.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20260..20862
                     /gene="ruvA"
                     /locus_tag="LP386_001912"
     CDS             20260..20862
                     /gene="ruvA"
                     /locus_tag="LP386_001912"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HBL1919147.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20875..21876
                     /gene="ruvB"
                     /locus_tag="LP386_001913"
     CDS             20875..21876
                     /gene="ruvB"
                     /locus_tag="LP386_001913"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HBL1919148.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21905..22483
                     /locus_tag="LP386_001914"
     CDS             21905..22483
                     /locus_tag="LP386_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL1919149.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22535..23017
                     /locus_tag="LP386_001915"
     CDS             22535..23017
                     /locus_tag="LP386_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HBL1919150.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23134..23508
                     /locus_tag="LP386_001916"
     CDS             23134..23508
                     /locus_tag="LP386_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919151.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7781 a         4285 c         5115 g         6646 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagttctcc acaaatcacc aagcttaact ataaatatac caaaaaaaaa acgttttttt
     1021 tctcaaaaat tgtatcttag aaacagcatg ttttgaaact ttcagaaaag gtttgttagt
     1081 aaaatgaaag ctatacgtaa ggagtgttgt ttgatgaaat tttttcaaga gtttttcatt
     1141 attattttct tttctgtatt aggagaaggc atacggattt ttgctcattt acctattcct
     1201 ggaagtatct taggtattct ttttttattt ttagcatttg aaatgcatct tgttgatcct
     1261 gaaaaaatcg gagcaactgg tgatttttta ttgaataatc tagccatttt atttgttcct
     1321 gctggtgtag gtttattgga atattttgat gatattgctt cgatatggcc tgttttactg
     1381 ggagcagtcg tcgtgtgttc catcgtcacg atggttgcag cgggaaaaac ggcagaaggt
     1441 gtagaagctt tgctgggcta tgtccgtaag aaaaaagcag aaagggtatc tgtaaacgaa
     1501 atggaggaga atcaaattga ctgagttttt tgtgaatcca ttatttggct taagtttgac
     1561 tttaggagtg tacgtattat ctgacaaatt tttgcggaaa tataaactgc ctgttttgaa
     1621 tcctctcgta ttatcgattg ttgttattat cttatttttg catttttctg ggatcagcta
     1681 taaagactat aatatcgggg gcaatttttt gactatgctg attactcctg cgacagtggc
     1741 acttgccatc cctctttata aaaacttccg tttactgaaa gagaattttt atcctgtaat
     1801 ggctgcgatt ttagcaggaa tagtcgcaaa ttgcttggtt agtgtagggt tcggttactt
     1861 cttctctctt cataaagaga tggtgatctc attactacct aaatctgtaa cgacggctat
     1921 ttctgtcgat ttatctcata cgatgggcgg ggtgaatgcc gtgacacttg ctattgttgt
     1981 ctctacaggt atttttggtt cgctgatcgc cactcatatt ttccgcctat tcaagatcga
     2041 aagtccagtt gctcgcggtg tggcgttagg aagtacttct catgctattg gtacagcaaa
     2101 agcaatcgag attggtgaaa tagaaggaat catttccgga cttgcgatat gcgtcaacgg
     2161 aatattgacc gttttattgc taccgttatt ctttcagcct tttgctggct tgttttgatg
     2221 cgaaaaccac tattttatgc tacaataacc aaaacgttcg agcataaaaa aggagggaaa
     2281 gacgtgtatt tgtcttccga gtatcttaaa caatttgata aagatctata ttataagatt
     2341 ctcctcctag aaagttttga ggatcaagct tggcataccg ctgcacaatt agcgcaagtt
     2401 gttcagctgg atgcccgcag cgtgtcgaaa tacctgaacg agctgtctaa aaactatcag
     2461 cagtttagcg gtaagacaca ccctttgttt acaaaaaatc accgttctgg ttataacttt
     2521 tatgatacgc tcgattcaat tgaacatgag cgttttttga tctatctcgt gcaaagtacg
     2581 ctgaaattcc agttgctgca cgacattttt tttgaagaat tccatacaat gtaccaattt
     2641 gcgcaaaagc attacattag tgaatctact gctcatcgaa aaatcaatga atggaaacag
     2701 caactgcaaa cttacggaat tcggctgcaa cgaggtacat atatcgctca aggcgaagaa
     2761 gaaatcattc gactttactt gcatatgaca ttctggcagt tgtttcgagg gaaaatctgg
     2821 ccatttgaaa cgatttctca aatggacgta aagaatatgg cagaacatat catggctttt
     2881 tttaatgttc gtctgaacga gatcaaaaaa agacgattgg aatatatgct aggtgccttt
     2941 tttttaagaa aatcacagaa gcattatgtt gtattgaatg agaaaaaaag acggctgatt
     3001 tctgacaatc tgttgttcca gcgattttgc caggtcatgg agccggtatt tcctaattat
     3061 tttcaagtag aagacgagtt aggcgcatta tttcttgtac tgatgactcg tgaagaatat
     3121 tatagtgatc ctaagatacg gaagaaaatt tttgattttc atcaacaagc aaaaacaccg
     3181 ccctttacag ccctttcaga agcaaaagcc gctctttctc tttatcagga agagcagggg
     3241 ctgccagcag aaaatctaac cttcgaggca gaaaactatt tattcagcag tcattttttc
     3301 gcctatcttt ttcctaatgc gaaagaaacg attgatggca atagtagtga ttttattaat
     3361 catttagtta ttgaaaacaa ggaattgaaa caatggctcg tacatttttt tgaaagtaga
     3421 cacaaacatc ccaatcatct ggcatttaaa aatcatgcgt ttttgatggg gcggtatctg
     3481 actgtgttta aaacattagg agcctttact ccacagcttc caaagatcac gatcctttta
     3541 atgacagatt tcccattatt tgaagagcaa ctgttagagg agggattacg gacatttttc
     3601 cgtaatgagt atcagctgat ttttctgcca acagattatc gggggagaga agttgatctt
     3661 ctgatttcga caagtaaagt ccaccgcaaa ccatgggcgg atcttgacta ttttattgtg
     3721 actgaagaac taaaattaat tgattacatc caactatctc aaaaatttga aatgattcaa
     3781 aaacaaaaac tattaaaaca ataacaaaga aggagaaaaa agatgacatt tgaagaaatt
     3841 ttaccagaat tgaaaaaagg tgcaaagatt attcgtaaag gatggagtgg atttgaactt
     3901 tatgttgttc tcgtatccga tgatgaattt gatggctgtc cggtgacgcc gtacttattg
     3961 atcaaaacaa gtgacgaagg tttttccagc ttcgctccta cagtttgtga tattttagca
     4021 gatgattggg cgatcgtaga atgaaaaacc agtatccaga tctagctaaa caggttgtat
     4081 ttatcacagg agctgcttct ggaattggtg ctgcgcaagc ccgagcgttt cttgaacaag
     4141 atgcttttgt atttggatta gatcaaaagt tcggtaaaat ggaagaaatt tctttgcgat
     4201 ttcctgaaac ttttgcctac gcactaggtg atgttcgaca aatgaaagaa ctccaacaag
     4261 cggtatcgaa atgccaaaat cattttggtg aagttacgat tttactgaat acagcgggga
     4321 tattggatgc ctacaaaccc ttgatggaaa ctgacgaatc gctgtgggat ctgatttatg
     4381 agacgaatgt gaaaagcatg tatcagctga caaaaatcat ccttcctgat atgatccgcc
     4441 aaaaaagcgg aacgatcatc aatatggctt cgattgctgg cttgattgct ggtggaggtg
     4501 ggatcgctta tacaagcgcg aaacatgcga ttgtcggatt taccaaacaa ctcgctctgg
     4561 attacgcagg acagggtatc cgagtaaaag gaattgctcc aggagccatc caaacaccaa
     4621 tgaatgcggc tgattttgaa gggaaaggtg agatggcaga gtgggtggca aatgaaacac
     4681 cagtcaagcg atgggcacag ccggaagaag tagctgagct gacgttattt cttgcctctc
     4741 ctcaagcaag ctacatacaa ggaacgatca tcccaatcga cggcggatgg ttgttaaaat
     4801 aaccttgtgt ttttttcaag cttctgtatg ataaaactaa agagagaaac aacggttgat
     4861 gataaaaaaa gtcgatgact gttcccgaca ttcgatgccg aacagccagt tcaaaaaatt
     4921 ctttttaata atcgttaata ttcgaaacta agcggctttt cacgacctct tgatataaac
     4981 gatattcaaa agcttgcaac tgcggtaaca agtccagcca aatgaaaaat ataaggagct
     5041 atttttattt gaccattctt attacttgtt gcagggcagc tttttcacta ccttctgcga
     5101 cacttcagtt ggaattttct tcccatcctt tggtcgcggt cattaccaag ataaaattat
     5161 cttgcaaagg agaaatagaa catggaaaaa aataataccc gttcagccaa acgctggaca
     5221 acgacagatg tgactcggat ggcgctagtc actggtttat atgtggcagt gacgctggtt
     5281 ttgtctgtct ttagctttgg agtgattcag attcgtctct cggagatgtt caactatctg
     5341 tccttgtata acaaaagata catcgtcgcg gtaacagcgg gagtagcttt ggctaatatt
     5401 gcttctcctc ttggactgat agatgttgca gtaggaagcg tcagcacgct gcttgtattg
     5461 cttatcaact ataaaatcac tagtcgcatc aaaaacatga aaatcaaaat ggccgtgaca
     5521 gcatgcgtat ttgctttttc catgtttaca gtagctggtc agctaacgat tttatatcaa
     5581 ctaccttttt tcttgaattg gtgggtgatt gctttaggag aattggcatc aatgattgtc
     5641 ggtgggataa ttatttattg gatcggtaaa aaagtggatt tgtcaaaata aagatctgtt
     5701 taatttaaaa tagggcagca tggaagagac tgaatgttga gtcttcttcc atgctgcttt
     5761 tttgattaat ttgtatgaag aaatcgattt agccgttttt tcatcaagat accgatataa
     5821 gctgctccag ttgccttgat tgcttccggc agtaaaaacg gcagtagtcc actggcaaat
     5881 gcagttgtaa aagtaagatc accacttatt ttcagccaga tcgttccgca gatcaatgca
     5941 gcaagagagc ccattagatt ggcaaagatt gcatataagt aatgagcatc cgttctttcg
     6001 atcatccaac cagttatcca cgtttgtaag agaaatccaa tcaaatatcc gccagttggc
     6061 ccaaataaaa cagctatacc tccagtcatc cctgaaaata caggaagacc aatcaagcca
     6121 agtaaaagat aaactccaac agatatcaat cctagttttc ttccgagaaa agttgctgtt
     6181 aatccaatag caaatgtttg ccctgtcaaa ggaaccaaac caaaaggaat ggtcatctga
     6241 gaaaggacag aaataatcgc ggcaaattcc gcagcaagta tcaattcttt caatgttcgg
     6301 ttcataacgc cctcttttcg ttaacttaat atttttattt ggttaacgaa attgtaaaac
     6361 aaagtgatta ctttgtaaat agaaaatata aaaaaagacc agctatccaa tagatagcgg
     6421 tctttttcaa gaaagctttt gaaattataa gctttggttg tagtattcaa cgacaagagc
     6481 ttcgtcgatt tctggatata gttcgtcacg ttctggtaaa cgagtcaatg aaccttccaa
     6541 tttttcagcg tcaaagctta cgaatgctgg gcgtccaaca gttgcttcta cagcttcttt
     6601 tactgttacg atgttttgtg atttttcacg aactgagatc acttgaccca cttctacgtg
     6661 gtatgaaggg atatcaacgc gtttgccatc aactaaaatg tgaccatggt taactaattg
     6721 acgtgcttga cgacgagtcg ttgcaagtcc taaacggtaa acaacattgt ctaaacgttg
     6781 ttctagtaag atcatgaagt taacaccatg tttaccttct ttgattttgc tagcttttac
     6841 gaacaagtta cggaattgac gttcgttcat tccgtacatg tgacgaagtt tttgtttttc
     6901 agttaattgc atgccgtatt ctgattgttt gccacggcta ttaggtccat gttgacctgg
     6961 tgcgtaaggg cgacgtgcta attcttttcc tgtgcctgac aatgagatgc ctaagcgacg
     7021 agaaattttc catgatggtc ctgtataacg agacattaaa atttcctcca atgaatataa
     7081 gtttttggag taaaataatc cgttgaaaaa ttcataatca tatagtttgt tcttcaatct
     7141 tcacctttgc agccgcggtt acacaatcga acccgagacg gggcaacaaa ctagggatga
     7201 gttattattt ttctgctgca ttattttaca caaattacag tatatgatag atcatccacg
     7261 aatgtcaaga taattagtac ataaaaacgc tttacaaacc taggctgtct ttataaaatg
     7321 agagggtatg tgcaaatgga aaaaagcgaa ggaagtttaa ggagaaaatc aatgaatccg
     7381 gtatcaccat tatttgagaa aatcgatgct tcaattgaaa agaaggcgaa tctttttgaa
     7441 aacagctttt cacgttacgc tgttcgagcg gttctcgcct gtttgttttt gactttagga
     7501 acggctgtgg catttgcgat cgcgatgaag ggggaagata tcgcgcatgg tctaggaaag
     7561 attttatacg catttatgtt cagctggggt ctggtcatga ttctatacat gaacgccgaa
     7621 ttaggaacat cgaatatgct ttatatgacc gtgggtgttt ttcggcagag acttgcttta
     7681 agtaaggcag ccaagattct atttgcctgt atttttttca atatgattgg cggtatatta
     7741 tgtggatttc taatttctat gactacgcca tttcaagatt taacgttgga caactttatg
     7801 ttagaatcaa tagcagtaaa actagcaaaa ccttcagcaa cgattttggt ggaagggatg
     7861 tttgcgaata tcgttgtcaa taccgctgta ctgatcagca tgcggatgaa agaggatgtc
     7921 ggaaaagtga tcacagtcgt attcatcatt ttcatttttg cttttttagg atatgaacac
     7981 gtgatagcga attttcctgc ctttacgctt acttactttg cttctcacgg acagatggat
     8041 ggaatgacag tcagcaatgt gttacataat ttgttttttg ctttggcagg aaattatatt
     8101 ggtggcggtt tagtaatggg actgggatat gcttggctga atcagtcaaa atcatcctat
     8161 gtggactaaa aagtcgttca ttaaagggga agtgccatgg aagttttagt ttttccaaaa
     8221 aatgaggaaa aagcgttaca aatggaaaag tacatgaaaa atcttttttc ctttgctgga
     8281 gtacctaagc cggaacgcgc tcttttacaa caaccgttac tggatgagag caaaaattta
     8341 tctatttctg aagttttagc ttttgttcat tattattatg aacaaatcga aagagagtat
     8401 cagtatgtag cgatcgattt agtccagaaa aacatcaaac ggcttacatt tgaagactta
     8461 gtcgtattgt tgccactagt tcagaaaaaa gaatggtggg acagcatcga ctcttggaga
     8521 aaagtataca gcacatggtg taaagcctac ccagagcagc gtgaagaagt ctttcaattg
     8581 tttgaaaaaa aggaagattt ttggctacgt cgaatagcaa tcacgttgca attaggttat
     8641 aaacagcaaa cagacacagg actattgatc cgagcaatag acgaagatcg tcaaacaaag
     8701 gaattcttta tccaaaaagc aattggttgg gcattacgcg attatagtaa gaccgatgcc
     8761 gattgggtaa aaagacagct gacaacagat ttgagtaagt tagctgttcg agaggcaagt
     8821 aagtatttat aagaaagcga gacgacaaga gatgagacgc aaattatttg cttttgatat
     8881 tgatggaacg ttgttagatt caaacaaaca agctttagat agcacaagag aagcattgga
     8941 aaaattacgc aaagccggtc atctggtcac gattgctaca gggcggagcc gatttcatgc
     9001 gcaagagatc attcgcgatc ttgattttac gaactacatt ttatgtaatg gagcggccgg
     9061 ttttttagac catgaacaag tatataagaa tttactagat cgcgaccagt tggatgcgtt
     9121 cgttcaagaa gcgcatcatg agcagatcga tacagctttt gtcagcttag acaatatcaa
     9181 gcgttcttct tccaatgatg taacggtgat ggaagaagcg atgcattctt tcggtgctgt
     9241 cttgcctgaa ttagatcagt tttttgcaga ggaacaagaa atataccaag cgttagcatt
     9301 tttcgatcaa acatatgatg ggaagttctc ttcatatgat aaaattcgat ttgtccgctg
     9361 gcatgagaac agtgtagatg tcgtacctaa aaatggttct aaagcagcga caattctgca
     9421 cttagcagaa caagtaggca tccctcatga agacatcatc agctttggcg atggacaaaa
     9481 cgaccgtgaa atgttgcgca tgtcaggaat tgggatagct atggggaatg ctgtgccaga
     9541 agtacaagca gaagctaaga tggtcactga tacaaacgat caggatggaa tttggaaggc
     9601 attgaaagag ttaagcgtga tttaaaagag gttgtgaaaa agctgttctg catcaagtaa
     9661 taagcccagc caaacaaaaa tagctcctcc tatttttcgt ttttctgggc ttattaccgc
     9721 agatgcaagc tttcgaacac cgtttaagga agaggtcgtg acagaagtgg tcagtttcaa
     9781 gaaataagaa gggatttacg aaaattgctt ctcaaatttt tgtaaaatta cggcttattt
     9841 ctgaagaagt agatgaaaca acgtttattc gggaaatggg actgtgacaa gatgtttgtc
     9901 atagtcccat ttttttattt tatttttcaa aactaagaaa taccaggaaa gagttccttt
     9961 tgtttgacct tttctttctt attgaaaaca actataatat agagtgatgt taaaagagaa
    10021 gaggaattta gtgtgcgggt attgtttatt ggtgatgtag taggttcaat gggacgagag
    10081 atgattactg aatatcttcc tagattgaag aagaagtacc gtccgcaagt aacgattgta
    10141 aatggtgaga atgccgcttc tggacgtgga atcacagaaa aaatctataa aaaatttttg
    10201 caagacggcg tagatgtcgt gacgatgggg aatcatacgt gggacaaccg cggaatcttt
    10261 gagtttgtaa atgaagctaa aaagatggtt cgtccggcaa attttccgga agggacgcct
    10321 ggacaaggga tggtctttgt caaagtgaac caagtcgaac tggcagtgat caacatgcag
    10381 gctcgttctt ttatggtgga cttggatgat ccttttcgta aaatgaatga gctggtagaa
    10441 gaagccagaa aacgtacgcc gatcattttt gtagattttc atggagaaac aacaagtgaa
    10501 aaacaagcaa tgggctggtt tttagatggg aaagtttcag cagtggtcgg tacacataca
    10561 cacgttcaga caaatgatgc gcgaattttg ccaagaggaa cagcgtatct gacagacgtt
    10621 gggatgacag gtccctatga tggtattttg ggtatgcgca gagaacctgt aatcgaaaag
    10681 tttctgactg cattaccaaa acgttttgaa gttgtggaac aaggccgatc gattttaagc
    10741 ggctgtatct tggaattgga tgatacgaca ggtcatgcaa aagaaatcca gctgattcag
    10801 atcaacgatg atcgaccgtt catggagtag aaagagaggc agttttttgc agcaggagcc
    10861 ggaaattcaa aaagaagtaa ggaaactgac aaaactttta agagagaatg aaacgatcat
    10921 tcgctacaaa gaacttgaag aaaagatcca gcaaaaccag tatttagctg agttgagaga
    10981 aaaaatcaaa caagcgcaaa aagatgctgt tcattttgcc cactatgaca aaccagcagc
    11041 agaaaaagaa gcaatcaaac aagcggatca attcatgcaa gaatttgatc agcatccgct
    11101 tgttgtagct tatagaaaac agctgttgga agcagatgat ctgcttcatc atttaacaac
    11161 tatgatacaa gaagaaatca atggacaaat agaggaggaa aaacatgcct caaaaaacta
    11221 aaaatactcc tatgatggaa caatatctaa gcatcaaggc ccaataccaa gatgcttttt
    11281 tgttctatcg tttaggagac ttttatgaac tattttacga agatgcgatc aaagcgtcac
    11341 agcttttgga attaacgttg acgagcagaa atcgaaatgc agaagaacct attcctatgt
    11401 gcggtgtacc tcaccatgca gcacaaggat atatcgatgc cttgattgaa aaaggctata
    11461 aagtagcgat ttgcgagcag gtagaagatc caaagacgac taaagggatg gtcaagcgcg
    11521 aagtgatcca gctagtcact cctggtacag tcatggacag caaaggattg tcggcaaaag
    11581 acaacaattt tttaacagct gtagttagtc aaggaaatga atttggcttt gcttatgccg
    11641 atttaagtac gggagaattg aagacggctc ggttgcatga tgaagaagct gttttaaatg
    11701 aagcctctgc attgcagaca aaagaactcg tattaggcag tgagatcact gatacccttc
    11761 gtgaacagct aagcgggcgt ttagggctag tcttttctca acaaaatgag atggaagaaa
    11821 acgcggaatt tagctttttg acaagcgaac tagtcgatcc gctggaaaaa gaagcaaccg
    11881 gcaaactatt gacttattta tcggtgacac aaaagcggag tttagctcat atccaaaaag
    11941 cagtagaata ccaaccagat cattttttga aaatggatta ttattcaaaa ttcaacctag
    12001 aattaagcca atctattcgg actgggaaaa agcacggcac tcttctatgg ttgttagatg
    12061 aaacaaaaac agcaatgggt ggccgtttac taaaacaatg gctagaccgt ccgcttatcc
    12121 aggcaaaaca aattaaagca agacaagaaa tggtcgcttc tttgctagac agctattttg
    12181 aacgtatcga tttgcagtca gcattaacga aagtctatga tctggaacgc ctagcaggtc
    12241 gagtagcttt cggtaatgtc aatgggcgag acttgatcca gctgaaaact tctttagaac
    12301 aagtgccaat gatcagaggg ttgattgaag gaatcgatca aggtcaatgg caaagtctgc
    12361 tttcagaaat gcagccgatg gaccatctcg tccaattgat cgaccaagct atccaagatg
    12421 atccgccgtt acaaataacg gaaggaaaca tcatcaaaga tggattcaat gagcagctcg
    12481 atatgtaccg ttctgctatg agaaacggaa agaaatggtt ggcagaactt gaagcaaaag
    12541 agcgtcaaga aacaggaatc aagaacttaa aaatcggatt taaccgcgtt ttcggttatt
    12601 atatagaaat tacaaaagca aatcttggaa atgcagaact ggagaagtat gaacgaaaac
    12661 aaactttagc aaatgcagag cgtttcatca caccagaact aaaagaattg gagacacaaa
    12721 tcctcgaagc agaagaaaaa tctgttgatt tagaatatca gttgttttta gctgtgagag
    12781 aagaagtcaa aaaggctatc cagccgctac aagtacttgc aaaagcaatc agtgcagtag
    12841 atgtgctaca aagttttgca acgatcagcg aacgctatca gtatgttcgg ccagaacttg
    12901 tcagtgacaa gcatcagctt ctgatcaaag acggacgaca tcctgtagta gaaaaagtat
    12961 taggacatca ggaatatatc cctaacagcg tagaaatggc agaagacgaa atgatcttgc
    13021 tgattacagg accgaatatg tctggtaaaa gtacgtatat gcgacagttg gcattaactg
    13081 ttctgatggc gcaaatgggc tgtttcgttc cggcaaaaca agcagtttta cctatttttg
    13141 atcggatttt tacccgaatt ggtgcaagtg acgacttaat tgctggacaa agtactttta
    13201 tggtagagat gatggaagcc aatcaagccc tgcgttatgc tacgccaaac agtttgattt
    13261 tgtttgacga actagggcga ggaacagcaa cctatgacgg aatggcgttg gcccaagcaa
    13321 tcatcgaata tatccatcgt catgtacaag caaaaacact cttttctact cattatcatg
    13381 aactgacggt acttgagaaa gaacttccgc agcttaaaaa tgtccatgtt ggagccgttg
    13441 aaaaagacgg agaagttgtc ttcttgcata aaatgatgga tggacctgcg gataaaagct
    13501 acggcataca tgtggcaaag atcgcaggat tgccttccaa tctactagaa cgagcagcag
    13561 atatcctgca tacgctagaa aatggcgata acggacacca tactgttcca gctgaagtag
    13621 aagagaaaac taaaacagcc aaacaggagc aaataaaacc acctgcagaa aaagtaaatc
    13681 aagaccatat acaagaccgt gtaaaagaag aaaaccaaca gctttcttta ttcagtgaat
    13741 tatccgaaaa tgaaacagaa gtcattgaat cactgaagca aataaattta ctagaaatga
    13801 cgccaatgga tgcactaaac acattatatg aattacaaaa acaactgtag gaagaaggcg
    13861 gatatcgatg gccaaaatcc aagaattatc tgaacgttta gctaatcaga tcgctgcggg
    13921 agaagtagtg gagcgaccag cttccgttgt gaaagaatta gtggaaaatg caattgacgc
    13981 cggcagtact cagattgata tcttagttga agaagcggga ctgcggacga tccaagtgat
    14041 tgataacgga gaaggcattt tggcagacga cgtagagaat gccttcaagc ggcatgcgac
    14101 aagtaagatc cataatcgcg acgatctttt tcgcatacga acgctgggct ttcgagggga
    14161 agctttgcca agtattgcct ctgtttctga aatgactctg gaaacggcga atcaggaaga
    14221 aaaacaaggc acctatctgt cgctgaaagg cggagaagtt attgagcatc gaccagcacc
    14281 actgcgtcaa ggaacgaaga ttaccgtcag caatctgttt ttcaatacgc cagcccgctt
    14341 gaaatacgtg aaaacactgc acacagaatt agcgaacatc ggggacatcg tcaatcgact
    14401 ggcattgagt catccatcga ttgcttttcg tttagtacat gatggaaaca aaatgctggc
    14461 aactgctgga aatggcgatc tgaaacaaac aattgcggga atctacggat tatctaccgc
    14521 aaaaaaaatg ctgaaaatcg aaggaaaaga tctagatttt gagttatttg gctatgtttc
    14581 attgcctgag gtgactcgtg ccagtaggaa ttacttatcg acgatcatca atggacgttt
    14641 tatcaagaac ttttccttga ataaagcaat cgttgcaggt tatgggtcaa aattaatggt
    14701 cggtcgtttc cctattgctg tattggaaat caaaatggac ccgcttttag tagatgtaaa
    14761 tgttcatccg acgaagcagg aagtccggct gtcgaaggaa aaagaactaa cagagctaat
    14821 tagtaacgcc attcaaaaag cattgtctca agaaaatctg attccaagtg cagcggataa
    14881 tctacggttt aagaaaaaag tacctgatca gcctaaaaca gaacaaatcg aaatcgattt
    14941 gtcctacgct tttgaagaag aaaaacctaa aaagccaagt agtttgaatt ttgatcgaga
    15001 gacaggtacc tttttcgtag aagaactaaa gaacacattt gttgacagaa ttgttgataa
    15061 gtctgtggaa aatgttgaaa actattctgg tttttctgaa gaaaacacca cttatccaga
    15121 aaaaacagcg aaaacggtgg ataagtttgg tgaaaatgtt gataactttg tagaaaaaac
    15181 agtggaaaaa tctgaaaaga aagaatttcc cattgtggat aacatggaga aaacaaatga
    15241 agaacaagca gataaatccg tagaagagga tgaaaagatt tacgaggaag aattgacact
    15301 ccatcctgaa tttgatttca ctcaaggaaa cgacaaaaca ttagaacaag ccatcaagaa
    15361 attagaaacg gaaaaaccag tacaacgttt tcctcagttg gaatattttg gacagatgca
    15421 cggaacgtat ctttttgccc aaagtagcga tgggttgtac atcattgatc agcatgctgc
    15481 ccaagagcgc attaagtatg aatatttccg ggaaaaaatt ggggaagtat ctgatgatct
    15541 gcaagaattg cttgttccat ttgtgttaga ctatccaaac agtgatgctt tgaaattaaa
    15601 agagcaaaaa cacttgctag aagatgcagg gatttattta gaagaatttg gtcaaaacag
    15661 ctttattgta cgggcccatc ctacttggta tcccaatgga gaagaagaat cgattattcg
    15721 ggagatgatc gatatgctgc tgacaactgg aagtgtgagt gtaaaaaaat tccgtgaagc
    15781 aacagcaatc atgatgagtt gcaaacgatc gattaaagcc aaccattatt tgaatgaagc
    15841 acaagcacgt gtgctgctga aggatctggc acgatgcgaa aatcctttca attgtcccca
    15901 tggccgtcca gtattgattc actttaccaa ttcggatatg gaaaggatgt tcaaacgaat
    15961 ccaagacccg cattaagtca aagagaagag ggaaaacatg aagattgtat tagcatccca
    16021 atcaccaaga agaaaagagt tattggctca tatcgtttca gaattcgaga ttgaacctgc
    16081 tgatatcgat gaaacgccat ttccagacga acagcccgtc gattatgttc gtagaatggc
    16141 tgaagaaaaa gcacgaactg tctgggaaca agatgaaaaa gaagaccatt tagtgattgc
    16201 cagtgacacg actgttgttc tcaatcaaga gatcatgggt aaaccagaag atctggctga
    16261 ggctgaattc atgctgaaaa aactaagcgg ggaaacacat actgtatata cagctgttgt
    16321 tttaaaaaca aaggaacgag aagaacggat actagcagaa gcacatgtca ctttttatcc
    16381 tttgacagac gaagagatca aacgctactt ggagacgggg gattatgcgg ataaggcagg
    16441 ggcatacggc atccaaaatg ctgcgagtgt attcgtcaaa gaaatttctg gagattatta
    16501 cagtatcgta ggatttccga ttggtgctgt caatcaggca ctgaaaacat tcatttaaac
    16561 aaaaaagcgg actatctgat tttcgattga aaatccatga tagcccgttt tttttattga
    16621 aaagattact tatctactct gactaagatt ttacttcagc tttaccgact gcttcgcccg
    16681 ggcgaacaag tcctgattgg tcaagagaaa gtcctgcaac tttttcatta ttggtcaaag
    16741 caacaataat gtcagttttc ttgccagctt gttctatttc tggcaaatcc atttcagcaa
    16801 tcagggtctc tggtgtgaca aggtatcctt ctttcacgaa tacattgaaa ggaacaccct
    16861 ttagttcaac agtatctaat cccatgtgaa caagtacttc cagcccctca ttagaaagaa
    16921 taccaatggc atgttttgtt tcaaagacac tcgtcacttt accgtttact ggtgcataga
    16981 ctttgccgtt tgacggttcg acagcataac cgtcacccat cattttttgt gagaaaactg
    17041 ggtcatttac ttcagttatt tccttgatgg tccctgcagc gactgcgaat aatgtttctt
    17101 ttgttgcaac tgccgtacca gttgctgaaa caggttcgaa agactgtggc gttgctgttg
    17161 cgccatttgc tgtttgaagt tgtacatcag cagcattttc aggaacagca ggatcaatct
    17221 tattcaaaat tccctgacgt ctaaagatga tcgtcaagcc aaatggaatg atgacagcaa
    17281 tgatcattgc gatgatgaaa ggtacccatg tttctgcttg gatagctagt attcctggca
    17341 aaccgcctac tccgatcgcg ttagctcgaa cacccatcaa gttagcaaac atgccagcta
    17401 atccagagcc gaccattgca gcgacgaaag gatagacgta tttcaaattg attccgaaca
    17461 tagcaggttc agttacgcct aagtaacaag aaatcattgc tggaatcgag atttgttctt
    17521 cttttttatt cccacgatgt aagaagatga tggctaagac tgcagagcct tgggcgatat
    17581 ttgataaagc aatcatcggc cataaattcg ttgatccgaa atctgcaatc agctgcatat
    17641 cgatggcatt ggtcatatgg tggagaccag taatcactaa aggagcatac aggaatccga
    17701 atacggcact aaacaaccag ctgatagaag acgtcaatcc agtatttacg atatttgaga
    17761 tccagcttcc gactgtccag ccgataggac ctaaaataac gtgtgcagct aaaacagttg
    17821 gtaacaatga aaacaatgga acaaaaatca tcgagatcga ctgagggata tatttgcgga
    17881 agaagatttc tagatacgct aacataaacc ctgccagcat ggctggaata acttgcgctt
    17941 gataaccaat catctggact tgagcaaaac caaaatccca aaatggaata tctgctgcgg
    18001 ctgtggaagc tacactataa gcatttaata attgcggaga aactaacgta attcctaaaa
    18061 cgattcctaa tatttgtgta gtacccatct tttttgcaat actccaagtg atacctactg
    18121 gaagaaaatg gaaaattgct tcacccggta accacaaaaa ggcattgaca ccattccaaa
    18181 acttcgagtg ttcaacgatt gttccaccaa gactttcaaa ctggatacct tcaagtacat
    18241 ttctgaatcc aaggatcaat ccaccgacaa tgattgcagg aatcagtggt gtaaagattt
    18301 ctgctaaaac ggcaatagca cgttgaacgg gatgaaggtt ttgttttgca gctgcttttc
    18361 cttgttcttt ggaaacccct tcaactccag atactgcaac gaagtcgtta taaaaagtag
    18421 aaacatcgtt tcctatgatg acttggaact gtcctgcatt cgtgaacatc ccttttacgc
    18481 taggtatatc ttcgatcgct ttttcgtccg cttttcctgg atcattcagg acaaaacgca
    18541 tacgagtcgc acaatgacta actgcagcaa tattttcttt tccgccgata tcatgtaaca
    18601 gcttctcggc atctgcttga tattttgcca tatcaataaa cccctttctc ttaacttgtc
    18661 tatgcaagtt gtttcttcat ttactatact ttttttcgga gagaattgca agcgttttat
    18721 taaaaagtac gagagaaaat gatatcgttt taaaaagctt aaaataagct tttcttaaaa
    18781 ataggaacat tgaaatacaa aaagagctgt agtatagtga agaaatgatg gaagaacgag
    18841 tgagggaaaa aacatgaata agttcaatga aattttttta gatttggaac agaaaatttt
    18901 agcgaaagaa tatcctccgc attcgctttt acccagtgag aaccaattga tcaaaattta
    18961 tggtgtttca cgagaaacaa ttagaaaagc gctgaatctt ttgactacgg aaggttatat
    19021 tcaaaaaaaa caaggaaaag gttcgatcgt actggatcgg aatcgcttcg actttcctat
    19081 ttctggattg actagctata aagagctaca ggagacccaa cgtattccaa gtgaaacgat
    19141 catccatacg ttagaagaaa cagaagtgac aaaagcattg aacgagatca ctggctggga
    19201 gatcggtgcg cctgtttggc atttgatacg cgaaagaaaa atcaatggcg aagtagttat
    19261 attagacacc gattatctat taaaggaaat cgttcctatt ttaactccag cacaagcaca
    19321 aggatcgatc tatgaatatt ttgaaaatga gctttctttg acgattgctt acgcgcaaaa
    19381 ggagatcaca gtagaagaag taacggaaat catgaaaaca gcgatggatc ttcacgatga
    19441 cacttatgca gtagtagtca gaagcctcgt tcatctggaa gatacccgct gtttcgagta
    19501 ttctgagtcg gttcaccgat tagataaatt ccgtttcgtt gagtttgccc gacgccgaaa
    19561 agtgtaaata gttcaaaaga aagcaaattg ttggcatctg tccactttgg cgctatgata
    19621 ggatcacaaa gggggcattt ttaatggata aaccaataag accagaaaaa gaagaactga
    19681 aagaaaagtt atcacccatg gcttatgcag tcacacaaga aaatgcaaca gaacgaccat
    19741 ttagcgggaa atatgatgat ttttacgaaa aggggatcta tgtagatatc gtcagcggtg
    19801 aaccgttatt cagctctgca gaaaaatatg atgcaggttg tggctggcca tcattcagca
    19861 aaccaataac gaaaagacaa gtgcgcgaaa aagccgattt ttctcatggc atgcatcgaa
    19921 tagaagttcg aagcaaagaa gcagattctc atctcggaca tgtgtttacc gatggaccag
    19981 tagatcaagg tggtctacgt tactgcatca attctgcctc actgaaattc attccatatg
    20041 aaaagatgga tgaattaggt tatggggaat tcaaatcact tgtagaataa tggaaataca
    20101 caaagagcgg tacaatacgg ggatttactc gatcgtccgc tcttttttta ttcaagcgat
    20161 tgctatttga aagaaacgct ccctagactc cttttttcac aaggtgaaat gtgctacaat
    20221 aaagggaacg tatgtgtgca aaagaaagag gactagaata tgtatgaata tctgacaggt
    20281 gtggttacct ttatcaaccc ctattacata gtagtagaaa ccaatggtat cggctaccag
    20341 atcgcactag gaaatcctta ccgctacagt agcaaactaa atcaaaaaat aaaaatttat
    20401 gtccatcagg taatacgtga agatgcgcat cttctgtatg gatttgattc gctagaagaa
    20461 aagcaactgt ttttgcgatt agtaagtgtt tcaggaatcg gtccgaaaag tgcccttgca
    20521 atcatggcaa gcgaagacca ctccggtttg attcaagcag tagaatccag tgatgtcact
    20581 tatttgacga aatttccagg agtagggaaa aagacagcac aacaaatgat cttggatcta
    20641 aaaggaaaat tcggtgagct gagtatcgat acacctttta gtctatttga tgaagcaaac
    20701 acaaaagacg ctacagctct atctgaagca atggaagctc tctcggctct tggttacagt
    20761 gatcgagaaa tcaaacgtgt agaaaaacaa ttaaaagaag tagataatca gacaacggat
    20821 gagtatctac gccaagcact caagctaatg atgaaaaaat aaggaggaga ccaaatgaca
    20881 gatgaatact tgttatcacc agaatctggc gaaaatgaac tgagtttgga aaaatctctt
    20941 cgaccacagc tgctttctca atatatcgga cagagaaaag tcaaacaaga acttcagatt
    21001 tacatcgaag ctgccagaaa tcgggaagaa cctttagatc atgttctgtt gtacgggcct
    21061 cctggattag gaaaaacgac gatggccatg gtcattgcta atgagatgac cgtaaatatt
    21121 cgtacgacga gtggccctgc tatcgaacgt ccgggtgact tagtagcaat cttgaatgaa
    21181 ctggaagcag gggatgtcct gtttatcgat gagatccatc gattacctag agtggtagaa
    21241 gagatgcttt attcagctat ggaagatttc tatgtagata tcatggtagg acaagggcca
    21301 accgcacatc cggttcattt ccctcttcct ccctttactt tgattggcgc gacgacacgg
    21361 gcaggtatgc tttctgcacc tttacgagat cgatttggca tcatttctca tatggaatat
    21421 tatgacgaac aggatctgca ggagatcgtt ttacgttctt cggatatttt tcaaacagag
    21481 atcattgaag aaggggcatt ggaaattgct cgccgatcac gaggaacgcc tagaatcgct
    21541 aatcgcttgc tcaaacgggt tcgtgatttt gcgcaagtcc aaggagacgg gaaaatcgat
    21601 cgtcctatag cggatcaggc acttactttg ctacaggtcg atcaggctgg attggattat
    21661 gttgaccaga aattgttgcg aacaatgatc gagttatatg gcggcggacc agtagggtta
    21721 agtacgcttt cagtaaacat aggagaagag cgtgagacgg tagaagatat gtatgaaccg
    21781 tatctgatcc aaaaaggatt tttaaagcgt acacctagag ggcgaattgc tactgcttat
    21841 gcctatgaac attttggtta cgactatcat atatgatttt tgcttttaga ttggaggaaa
    21901 atgaatgagt gatacaacac gtacgaaaca attgatcaaa aacgtattga ttgatttgtg
    21961 ccaaacgcaa tcttttcgaa aaatcagcgt ccaaaaaatc gcaaacgaag caaaaatcaa
    22021 tcgacaaaca ttttattatc attttacaga taaatacgat ttgcttcgtt gggtctattg
    22081 tgaggatgca ttgcattatt tagatccaca atgtctttca cttgataatt gggaagagca
    22141 agcattgaaa atgctgaaag caattgctga gaagaaagaa ttttatgcaa atactgtgct
    22201 ttctgaccca gaaattttac aaaaagagtt ttctcaactg atccaaaaat catttatcaa
    22261 gatttttgaa caaatggatg aagaaagaca actttctgca agagacaaac tattttatgc
    22321 tcgttttttt tcttacggtt gcagtggtgt attagtcaat tggatcacga atgaatatga
    22381 agaaacaccg atggaaatcg ctatgcagct tttccgttta gccaaggata cggaattata
    22441 ttcttatcgt ctttatgcaa aagaagagtt ggaagaacag taatagaaaa attttttgtt
    22501 ggaaaagcaa taatcgctaa aaggagatgg ggaaatgaca aaaattttat ttgtttgttt
    22561 gggaaatatt tgccgttcac cgatggcaga aggcttgctg agaaaacgaa tagcattaga
    22621 aggaagggaa gcagaatttt ttgtggattc tgctgctaca agcacgtatg aagttggaaa
    22681 gacaccgcac cctggaacga aaaaaatatt aaaccaagaa aaagtagata tgacgaatat
    22741 ggttgctcgg caaatcacac cccacgattt tgaaactttt gattggatca ttggcatgga
    22801 tcaagaaaat gtagaagaac tgaaacgaag agcaccacgc tcagcgcagg ggaaaatcca
    22861 tttgttttta agtagcattc ctggaaaaga aaaagaaaat gttcccgacc catactatac
    22921 caataacttt gatgagacat atcacttgat cacagaaggc ctgaatcatt ggtggaatat
    22981 ttggattgat gaaaataaaa taacaaataa tttgtaaagt taacgctttc tttttaaggc
    23041 gatgttagag catttccttg tttttttgta aaatgttagg taaaataaaa ttaattaagt
    23101 aacactttct tagctaaagg aggagtgcat tcgatgaacg aagagacagt atcgccaatg
    23161 aagaagctta cgaagttagt tactcatact tcgtatcaac tttttgattc ttttgtaaat
    23221 gacactgaag aacatgctaa gaatgtacga ttgcaaggaa agtttattct tgagctgcaa
    23281 aaagctgcta ctgaacatag tctagttatc ttacaagtaa gagcaaatcg tttgagtagc
    23341 aagtatgaaa cgatctcagg ctgggtggcg acaaaaacgg tcgaaaaaga ccgagtgatg
    23401 atccgcctac aaaacgaaga gcagcagatc cggatggttc ctgtagaaca aattgaaaaa
    23461 ataacaatcc tttcaccagc aggggaacag gaacggttat caaaataatt tataccagat
    23521 agaaaagcac gtatgagctt gtaccatcaa tcattactaa tcaaaaataa ccgaatgctt
    23581 taagctgata tcagtaaaac ggaacgtttt aggatgagta tcatagcatg acagcattcg
    23641 gttgattagt tgaatcgatt ggatggtaca agtttttttg ataaaaaaag gtcctgctag
    23701 ccggggagct agcaggataa ggagttaaaa atgaaaaagt gttgttaggg ttgtttgttg
    23761 gtatgcttat ataatagtca ttagttgtga atattttgtg acgaaagttt tcgaaagttg
    23821 ttaagtt
//
LOCUS       DAFEKH010000042        23657 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.043, whole genome shotgun sequence.
ACCESSION   DAFEKH010000042
VERSION     DAFEKH010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23657)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23657)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23657
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.043"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            255..530
                     /locus_tag="LP386_001917"
     CDS             255..530
                     /locus_tag="LP386_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919152.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            543..2621
                     /locus_tag="LP386_001918"
     CDS             543..2621
                     /locus_tag="LP386_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBL1919153.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            2781..4667
                     /locus_tag="LP386_001919"
     CDS             2781..4667
                     /locus_tag="LP386_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBL1919154.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            4679..5626
                     /locus_tag="LP386_001920"
     CDS             4679..5626
                     /locus_tag="LP386_001920"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HBL1919155.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            5646..6173
                     /locus_tag="LP386_001921"
     CDS             5646..6173
                     /locus_tag="LP386_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBL1919156.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(6236..6889)
                     /locus_tag="LP386_001922"
     CDS             complement(6236..6889)
                     /locus_tag="LP386_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBL1919157.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            7021..7863
                     /locus_tag="LP386_001923"
     CDS             7021..7863
                     /locus_tag="LP386_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBL1919158.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            8021..8917
                     /locus_tag="LP386_001924"
     CDS             8021..8917
                     /locus_tag="LP386_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBL1919159.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            8920..9633
                     /locus_tag="LP386_001925"
     CDS             8920..9633
                     /locus_tag="LP386_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HBL1919160.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            9653..10171
                     /gene="msrA"
                     /locus_tag="LP386_001926"
     CDS             9653..10171
                     /gene="msrA"
                     /locus_tag="LP386_001926"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBL1919161.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            10168..10395
                     /locus_tag="LP386_001927"
     CDS             10168..10395
                     /locus_tag="LP386_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HBL1919162.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            10547..11098
                     /gene="lepB"
                     /locus_tag="LP386_001928"
     CDS             10547..11098
                     /gene="lepB"
                     /locus_tag="LP386_001928"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBL1919163.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(11181..11681)
                     /locus_tag="LP386_001929"
     CDS             complement(11181..11681)
                     /locus_tag="LP386_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBL1919164.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(11960..12358)
                     /locus_tag="LP386_001930"
     CDS             complement(11960..12358)
                     /locus_tag="LP386_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL1919165.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            12618..13478
                     /gene="ylqF"
                     /locus_tag="LP386_001931"
     CDS             12618..13478
                     /gene="ylqF"
                     /locus_tag="LP386_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HBL1919166.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            13471..14238
                     /locus_tag="LP386_001932"
     CDS             13471..14238
                     /locus_tag="LP386_001932"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HBL1919167.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            14294..15151
                     /gene="dprA"
                     /locus_tag="LP386_001933"
     CDS             14294..15151
                     /gene="dprA"
                     /locus_tag="LP386_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBL1919168.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            15273..17351
                     /gene="topA"
                     /locus_tag="LP386_001934"
     CDS             15273..17351
                     /gene="topA"
                     /locus_tag="LP386_001934"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HBL1919169.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            17320..18696
                     /gene="trmFO"
                     /locus_tag="LP386_001935"
     CDS             17320..18696
                     /gene="trmFO"
                     /locus_tag="LP386_001935"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HBL1919170.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            18894..19799
                     /gene="xerC"
                     /locus_tag="LP386_001936"
     CDS             18894..19799
                     /gene="xerC"
                     /locus_tag="LP386_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HBL1919171.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            19836..20384
                     /gene="hslV"
                     /locus_tag="LP386_001937"
     CDS             19836..20384
                     /gene="hslV"
                     /locus_tag="LP386_001937"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HBL1919172.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            20398..21798
                     /gene="hslU"
                     /locus_tag="LP386_001938"
     CDS             20398..21798
                     /gene="hslU"
                     /locus_tag="LP386_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HBL1919173.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            21816..22607
                     /gene="codY"
                     /locus_tag="LP386_001939"
     CDS             21816..22607
                     /gene="codY"
                     /locus_tag="LP386_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HBL1919174.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            22689..23564
                     /locus_tag="LP386_001940"
     CDS             22689..23564
                     /locus_tag="LP386_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBL1919175.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
BASE COUNT         8192 a         4079 c         4983 g         6403 t
ORIGIN      
        1 tttgtcgcag ccccattttt ttgttgtgat aaaagaacaa gaaaggcagg aatgggaaag
       61 taaacatcct tttgtcagaa acttttatct ttcttaagtt ttacttgata tctgatacta
      121 tttggaatag aatgaggcgt tgaaaaattt atggaaattt ctaactagca ataaacgatg
      181 aaacaatgaa atatttttca tccaaaaaga actttgctat aatgatggaa gtttgtgtat
      241 aggagatctg gaaaatgaga gagagttttg aacaacaaaa aaaactgttg catgatcgct
      301 atggcgccct ttcgatggat gaccgccgtc aaatactttg taagttgcgt aaaagaaata
      361 tattgatgta tcgtcagttg gaacgtctga aacatgatct gcttcgtttg gagtcaaaac
      421 gtgtacagtg tgaattagag gggaaccaaa cacaggttga agtagtcgaa accaaaattt
      481 taaagaaaaa agaacaattt ttaaaaatgc ttacacaaaa taaaaaataa aggggatgga
      541 cgatggaatt tgctgagtta gttattgtat ttgcagtaac gatcacctta tcgaacatag
      601 ctagccgcat tttgccaatg attccagctc cactgatcca aattttcctt ggagtggtat
      661 taggtctgac agagtgggga caatcaatcg attttgaacc tgaattgttc ttagttatga
      721 ttattgcacc attgttattt agagaaggag aaaaagcaga tatttcttcg attctcaaaa
      781 atttcgggac aattttgttc ttggcatttg gaggagtcat tttgaccctt gtcggggtag
      841 gtgcgacgtt atcattcctg ttgccaagtg tcccacttgc tgcctgcttt gcttttggag
      901 cagcgttagg tccgacagat gcggtagcag tcagttctct ttctggacga gtgaatatcc
      961 ctaaaaaggc gatgcatatt ttggaaggag aaggtctttt gaatgatgca tctggtgtta
     1021 ctgccttcca gtttgctctt ggtgcgctga tcaccggatc tttttcagca gtaaacgcgg
     1081 ggatgagtct agtagtttct agtattgggg gagctttgat cggctttttg cttgtctggt
     1141 tcaaacaaaa aataattcat ttgatcgaaa aagcatcagc acaagatgtc acagggtatc
     1201 tgctgatcga acttttgctt ccttttctag cctatgtatt ggcagaggca tttgatgtat
     1261 ctggaatcat tgctgcagtg gcagcaggta ttctccaagc ttctggtttt aggaaaatct
     1321 ctgtgtttga tgcagaattg tcgagcttgt cccacagtac atggacaact attgctttta
     1381 cactgaatgc attagtattt atatttttag gaatcgaatt gacgcaagtg ttctcgccag
     1441 tatggggaga cggtttatat ccaaacggtc ttttattagc gattatcgta ttaatctctg
     1501 tcatgctttt tgtgatcaga ttcatttcta tcagtctttt ttatgtattc aaagatggca
     1561 gtaaaaagtt caaaaaacag ttgaacgaga tcttgatctt aacatttggc ggtgtaaagg
     1621 gaacagtcag tttggctacg atttttattt tgccattttc aatcaataat atgatgtttt
     1681 accagcggtc tttgcttttg tttctgacgg cgggtgtcat cttagtgact ttggtcatag
     1741 ggatcattgt cttgcctatg ctgacggaaa cagaggaagc gaaaagcacg gatttgaatg
     1801 ctttgatgat tttagaagag gtcgttgaag ttttgcgaaa agaaataaag gaaattgatc
     1861 gtaatacaaa agaattttta gccactgaag cagtgataga aaattatcaa gaacggatac
     1921 gtgatctgta cttggaagat ttaaccgatg atgaaaagca agaagtacaa gaaatacaag
     1981 cactgatttt gtcgatcgaa cgggatggat tggatgaaag ttatcgttcg ggcaagcttt
     2041 cttctaatgg ttatcgtttt tactcccgtt ttctttctcg attcgaacat tctatcacaa
     2101 gccagatttt gtcttttatc ggcttttggt tcattgttgt ccgtaggtta atgcgaatcg
     2161 ttctccatcc gaaaatgttt tggcaaagaa gatatgctga tcgtcagaca tttattagtg
     2221 atgaagatat ccaagaaatc agagagacat atcaaaaaaa tactcagttg attattgaaa
     2281 gtttagataa cttgactgat atttatgatg aaacgatggt tcaatttttt atccagcaac
     2341 gcaaacttga aggaataaaa atgaactcgg ggaatttgat ttcttcgtgg atgatccagc
     2401 aagatagtct gtttacgaaa aaaatgctaa gaggttatta tcttgaaaga aaaatcattg
     2461 atgaatacga agttgctgaa aaaatcacga cgttttctgc gaacagctat cgcaggaata
     2521 tcaatttgtt agaatcttat acgatgaaca aaccatctga taacttttct ttccgatttg
     2581 cgtttcgagc aaagtcaaaa aaaacgagtc caataaaata aaaaggtaaa aattttcaag
     2641 ttttataaaa aacaaaacat atcagaacag gatcgaatcg gtcctgttct ttttttgaga
     2701 acacaaaaag aacaaatacc aaaaaaattt tcctgaagtt cactattttt atgatacaat
     2761 atccaagata aggagggaac atgttgaaag aattaaaagt aactgacctc aaaaaaactt
     2821 atggtgaaaa agatttgttt gaccagattt cttttttggt ccacgaaaaa gaccgtatcg
     2881 ggttgattgg gacgaacggg acgggtaaaa caagtctctt aaatattatt gccggtatcg
     2941 atagcagcga cggtgatcgg caaacagtgt tttatccaac tgattaccgt attggttatc
     3001 tttctcaagc agctgaattt tccgatgaat taactgttct ccaagcagtc tttcaaggaa
     3061 acagcccctt gatccaaact gttcgagcat atgaggaagc attgatcgaa ctaggggaaa
     3121 acggagaaga ccctgatgtg caaaaacgtt atgctaaagc agaagaacaa atgaataaag
     3181 aagatgcttg gactacagat accaacgcaa agattatttt gcaaaaatta ggaatcagtg
     3241 aattagataa aaaaatcagt actttatcag gtggtcagaa aaaacgagtt agtctggcgc
     3301 aagtgttgat tgatgaaccc gatttactat tactagacga accaacaaac catttagatt
     3361 atgaagcgat cgagtggttg gaaaactatt tgaaacaata ccgtggcgca ctattgatgg
     3421 ttacccacga tcgttatttt ctagatagag tagcaaaccg aatcttcgaa ctttcatttg
     3481 gaaaattata cgagtataaa ggaaattatg aagcttacgt cttagaaaaa gcagaacgtg
     3541 atcgtgtaga agtagaacaa gaagaaaagc gcaagcggct ttataaacag gaattagctt
     3601 ggatgagggc tggcgtacag gcacgtggca ccaagcagca agcacggatc aaccgtttcg
     3661 aagatctaaa ggagaacttg taccaagtaa accaagaaga tgatttagag ctgaacctag
     3721 cgacacaacg tttagggaaa aaagtactgg aaatcaaaga tggcagttac cgtataaatg
     3781 accaaacact gctagaacat ttagatttat tgattcaatc tcgggaaaga ctaggtatta
     3841 ctggtaaaaa tggtgcggga aaatcgacat tgcttaatat tctagctggc agaattcccc
     3901 tggatagcgg tacaatgtct atcggtgaaa cggttcatct tgcgtattat acacaagaaa
     3961 atgaagaaat ggcaccagat aaacggatga ttgcttactt acaagaagct gctgaagaag
     4021 caaaaacagc agatggcagt caaatcggag tagcagaatt acttgaacga tttttatttc
     4081 caagatttat gcatgggaca ctgataggca aactttcagg cggagaaaaa cgccggttat
     4141 ttttgttgaa actgctgatt cagcaaccta atgttttatt attggatgaa ccgaccaatg
     4201 atttggacat agcaacattg acgattttgg aagattattt tagaagtttt ccaggtgctg
     4261 tgatcactgt ttcccatgac cgttatttct tggacaaggt agcagataag ttattagtat
     4321 tccaaggaaa cggaaaacaa gaactttatt acggaaacat gtccagttat ttactgaagc
     4381 aaaaagagac ccagcagcct gctgaaaaag cgaaaccaaa aatacagagc aaggaacctg
     4441 ctgaaaagaa gaaattatct tacatggaac aaaaagaatg ggaaacgatt gaagatgaga
     4501 ttgcagaact tgaagaaaaa atctcattgc tccaagaaga gatgaatcat caaggagata
     4561 atttcactcg attacaagaa ttgcaaaacg acgtatctga aacagaagca caacttgaag
     4621 aaaaaatggc acggtgggaa tacttgagtg aatgggtaga agattaggag gaaaaaggat
     4681 ggaacaagcg tatcttgact taggaagaaa attgttggaa gaagggcatc gtaaagaaga
     4741 cagaacaggc acaggcacat taagcttatt cggataccaa atgcggtttg atctgcaaaa
     4801 agggtttcct ttgttaacaa cgaaacgagt accttttgga ttgatcaaaa gcgaattgct
     4861 ttggttttta aaaggagata cgaatatccg ctatctatta caaaataaaa accatatttg
     4921 ggatgaatgg gcatttgaac gctacatcaa aagtccagac tataatggac cagatatgac
     4981 tgattttggc catagatgtt tgacagatcc tgaattcaat gaagaatata aaaagcagag
     5041 caagcttttt tgcgagaaga tcctaaccga tgattccttt gctgaaacat acggcgatct
     5101 tggacacatc tacggctatc aatggcgtca ctgggaaaca aaagacggtg gctttatcga
     5161 tcaaatcaaa caagtgatcg aagcaatcaa aaagactcct gattctagaa gattgatcgt
     5221 ttctgcatgg aatccggaag atgttcctag catggctttg cctccttgtc atacgatgtt
     5281 tcaattttat gttcaagagg gacggctaag ctgccaattg tatcaacgca gtggggatgt
     5341 gtttctaggc gttccgttca acattgcaag ttatgcgttg ctgactcacc taattgcaca
     5401 tgaaacaggt ttagcggttg gcgaatttgt tcacacatta ggagatgctc atctttatat
     5461 caatcatatc gaacaaatga aagaacaatt gagccgagaa atacgcgcat ttccgacttt
     5521 agttttgaat caggaaaagc agtcagtatt tgattttgag atggaagata tccaattaga
     5581 aggatatgac ccacatccgg cgatcaaagc tcctatcgct gtttagaatc agaaaggatg
     5641 agaaaatgtt agctgcaatt tgggcacagg atgaaaacgg attgattgga aaagaagacc
     5701 gtcttccttg gcgtttgcca aatgatctga aattcttcaa acaaatgaca gaagcaaata
     5761 cactagtgat gggacgaaaa acattcgaag ggatgggtag ccgtccgttg ccgaatcgtc
     5821 agacgattgt tttgacgaga gattcttcct ataaagcaga aggcgtgcat gtcatgcata
     5881 gtgtggaaga cgtgcttgct ctggaaaaag aaacagacgg tatctttttc atcgctggag
     5941 ggtcagctgt ttatcaagaa tttctgccat tttgtacgat attataccgt acagtcatcc
     6001 atcatgtatt cgatggagat gcttattttc cacctgttga ctggtctgat tggtcactga
     6061 tcaatactag tcaaggagaa atggatgaaa aaaatcgtta tccgcatcaa tttgaaacgt
     6121 atcagcgtaa tgagaatcct gtaaaaagcg ggacaggcga attgacgata taaaaaagct
     6181 atggatagac tagctgttat ttagagctgt cccatccata gctttatttt ttttattaag
     6241 taaagaataa aacagagaag tacataaaac ctgcacctaa cataacaaac aaatgccaaa
     6301 caacatgcat atagcggata gaattcaagc tataaaagaa tgcgcctatc gtgtaagaaa
     6361 gcccgcctgc taccatcaaa ataacaccag tcattccaag agagtgataa agaggaacag
     6421 cagccacgac acagagccac cccataaaaa tatagatgat cgtagatact tttgatactc
     6481 tctcccgttt atgcaacgtc aacgctttat atataatgcc aagaatcgca aacaaccaga
     6541 ttaatacaaa taaagtccaa cctagccatc ctcggatact cagcaaacaa aaaggagtat
     6601 aacttcctgc aatcaaaaga aaaatcgaac tatgatcgaa tacttggaac accttttttg
     6661 cttttgtaaa aatcaatgaa tgaaacaaag tagacgttaa aaataaaaga atcatcatcg
     6721 atccatagat agcataagag acaatatgga gggaggaatg caagtgggca ccttttacta
     6781 aaagaaccac tagtcccgcg atactcaatc cagtcccaat tccatgggtg actgcattaa
     6841 acacttcatt taatatttca tacgttcgat taaatttcgt tttttccatg aaaacggctc
     6901 ctttactagg tgtaattaat gaaaaatcat tatttgtctg ttatactaaa aatagaaatt
     6961 gtcttacatg tagtttaaca tgaataaggc atcttgttaa agaaagagag agagaaaata
     7021 atgacaaatg taaaaatcgt aacagattct tcatgtacga tggaaaaaaa tgtacgcgat
     7081 gctttaggca ttcgtgtcat gccgctatcc atcatgatcg acggaacagt atatcccgat
     7141 gatgaccaac tagacggcga aagatttatg gaaatgatgg cgaaagcaaa aaatctgccc
     7201 aaaacaagcc aaccaccaat tggagaattc atctcgatgt atgatgagct aggagaagac
     7261 ggcagtgaag tgatttcgat ccatatgaca aaaggcttga gtggaacagt agaagcagca
     7321 agacaagcca gtaatctaac aaaaacgaaa gtaacggtta tcgacagtga taccactgac
     7381 caaggattat cttttcaggt aattcgagca gctgaattag caaaagaagg taaaacagta
     7441 gagaaaatcc ttgaagaagt caaaaaagta caagacaata caaaattata catcggaata
     7501 tccacactag ataacttggt aaaaggtgga agaatcagcc gaacaactgg tttgctgtct
     7561 agtgttttga acatacgcgt ggtgatgaat ttcgcccatt ctgaattaat ccctgtaact
     7621 aaggggcgag gaaagaaaac gttcgataaa tggtttaata atttgaaaaa tgaactgaaa
     7681 gaattgccaa atgtgcgaca aatcggtatt tcacatgcgg atgcaaaaga attggcgcaa
     7741 gaattcaaag agggtttgca agaattattc ccggacatgc atatccctgt actgcatacg
     7801 aatccggtta tcgctacgca tactggtaaa gacgcgtttg caatcatgta ttatgtagat
     7861 tagtcgaaaa gaggataagc cctcagcctg aaaggcttgc agcttattct ctttttcttt
     7921 ataaaattag gaaaataatt gttttctttt ttcataaaga ctaccttttt gataaaattt
     7981 ttgataacat tagaaccaat cgaatacaag aggtgaaaaa atgaaattaa cgaaacgaca
     8041 tttgatcctc gttttgttcc cattattaat tgcgatcatc atctatgcag gtttagctgc
     8101 ttctataccg aaagctggcc cactaatgaa accagtaact actgtgagag aagatccaaa
     8161 taaaaaagaa aaacttcact acatagctat cggagattcg ctgactgaag gagtaggaga
     8221 tcaaaccaag caaggaggat tcgttcccct tgtcgcaaat gatctaaaag accgttataa
     8281 tttgaccgcg gttgaaacag aaaactatgg tgtaaatggt gaacgaagtg accagatctt
     8341 aaagcgagta aaaacaaaag aagaaattcg aaacaatatc aaaacagctg attttatcac
     8401 actgactgtt ggcggtaatg atttgatgaa agttatccaa aataatttat tcgggttaac
     8461 ggtcaattcc tttaaaaagc cactgaaaaa ctatcaggaa aatgtcacag aactattgga
     8521 agaatttcga tccctcaata aaaccgcacc tatttacatt ttaggcatct acaatccatt
     8581 ttatttgaac tttcctgaga tcactgacat gcagacaatt gttaacaatt ggaacaaagg
     8641 aacagaaacg gtgacaaaaa aaatgccgaa ctgctacttt atcccaatca atgatttgct
     8701 ttatcaagga ttgaatcagg aagtaggtgt cacagaagaa ggaacagatc aaacaactag
     8761 cacgacagaa aatctaaatg gcatcaaaaa taatgtgctc tatgaagaag atcatttcca
     8821 tccaaataat ttaggttatc aattgatggc aaatgcagtg agagatcagc tgatcgagac
     8881 acaaaaccaa tggttagaga aggaggatga tcaataaaca tgaaaacaag atctgacgta
     8941 tcttcaaaca aaacaaagaa aacaaattac tggaaattcg ccttccttat ccttcttggg
     9001 gtagtacttg gttcgaccgt atttttaggc agccgtattt ttgctaatcg ggaaccagaa
     9061 ctcccagaaa taccagctct tacggaaaga caaggagatc ctgtcttaac gatcaattca
     9121 aataaagaaa aagtcaatca aatcatcagc tttttcctta gtgagtatca aaaagatagt
     9181 gatattgaat ataaatttta tttggaaaat gaagcactac tcaatggtac tttcgaagta
     9241 ctaggttttc ctatcgattt ctatttatat tttgatccgt atgtgatgga aaacggaaat
     9301 gtccaactaa aagctagaag tctttctatc ggaacattga gtttgccaat caaagatgtg
     9361 atgaatatga tcaagagaaa ctataaatta ccagattgga tcgaagtcaa tacagatgat
     9421 ctgactatca tgcttaggtt ggatcaattc cgaatgcaaa acgggatgta tattaaagca
     9481 gataaaatcg acttagtaaa tgatgacatt cggtttagtc tatatttgcc aaaagatacc
     9541 tctgatgctt caaacaactc aaataccaac aaaactagca ccagcagtac tgaaagcaag
     9601 acaaaagaaa ataaaaaatc atcggatgag tagtattaga gggggaatca taatggaacg
     9661 agcaatattt gcaggaggct gcttctggtg tatgatccag cctttcgaca cgcttcctgg
     9721 tatccataca gtgatgtcag gatatactgg agggcatgta ccagatccga cttatgaaca
     9781 agtaaaaagc caaacgactg gacatacaga agcagtggag attatctatg atccaacatt
     9841 gatttcatat gaacaattag tagaacttta ctggcagcaa actgatccaa ctgacgcttt
     9901 cggacaattc gaggatcgcg gtgacaatta tcgcccggtg atcttttatt tgacagaaga
     9961 acagcggatc attgctgaaa aaagtaagaa acagttagct gaaagtggac gtttcgaaca
    10021 gccaatcgtt acaaaaatcg aaccagccca accattttat ctagcagaag aagaccatca
    10081 agagtattat aaaaagcatc ctgaaaattt taaaagaaac catgcacgcc gggctgcctt
    10141 tatcgaagaa aattggagga acgaagggtg aatcgaagct tttttcatta tttaatgaca
    10201 ctgcgaggcg gtggcacaca tgatgcttta tctgttttcg ctacagaagc cggtaaagac
    10261 atccaatttc ctaagcacag ctctagctac gaagaaattt ctaattatct ggaactgaat
    10321 gtcgactatt tgccgtccat ggatatcttt gacgaagcat gggaaaaata tttagaaaat
    10381 aatcatgaca tataagagat agttttgtac tttatgatca aaaaagtttt ttgtccaata
    10441 gcctaattga aagaattatt tttatttcag ctatctagtc gcattttttt gatatttttc
    10501 ttataataaa gaaagaatga aaaaaagagg gatggattga tagagattga caaaaaaaca
    10561 acgctatatt aatcgcttct ggcttgtatt caaatactta cttgtttctg tattccttgc
    10621 gttcatgttg cggggatttt tattcatccc ggtaccagtg gaaggcaatt caatggaaaa
    10681 cgtgttgaag caaggtgata tggttgtgat ggaaaaattt tcggagatca gacgatttga
    10741 tattgttgtt tttcaattag cagatggcac gatttatatc aaacgagtaa tcggtcttcc
    10801 aggagaaaat gtcagctacc aaaatgatca attgaagatc aatgggaaag tagttaagga
    10861 accttatcta actaaaaacc tgaaatcaga tcatgcaaat gcatcctata cgacggactt
    10921 tacactacaa gagctaacgg gacaatccaa gcttccggaa gataattatt ttgtacttgg
    10981 agataatcga agagtttcaa aagatagtcg ttcgtttggc acgatcaata aaactgatat
    11041 tctaggtaaa gcaagatttg tctattatcc acttgatgaa ataaaatgga tccagtgaga
    11101 aacaataaag cgtgcagtct gttgagactg cacgctttat tgtttaatcc aaaatcagtt
    11161 tactacctta gtacgtaaaa tcaaacagct cgtttaaaca cttttctagc ctctaaagtt
    11221 ttgataaatg aataaacaac cattatttga atagggattt ggatcatatt cctgatgaat
    11281 ctacctagaa aaattacttt gaaatctgca ccaaacaaaa cagacatcag ccaagaattg
    11341 ataaaaaggc tgactgggat cataatcaat aattgggcag cgatgacgga aggcaggttt
    11401 atctttttat gatataaaaa taagccatta ataaatccac caaggaaagc cgtgataaga
    11461 aaagcagctt gaaacgttcc tgaaccaaat atcgtgaaat ttaaagtgtt cgacaacatt
    11521 tcaagcaaac cagcccagat cggtccatat agataaccca taagcgccat acttaaaaat
    11581 ccgaatgtga tttgaaaata agcaggacca atcgctatct tgtataagat gacatcaagg
    11641 gctaataaaa gagcagaggt cgacaacaat cttgcattca tttcgggcaa tctaaaaacg
    11701 tcttttgcaa tcaaagtgtt caaaatattc tctcctttgt cagttaataa taaaaggata
    11761 ccataaaatc accaatgtgt catgacacat tggtgattta catacactgg catctaacaa
    11821 ttaaaaaaag ggtgagaaga ctgcttttat aaactgtaaa aaagagattg tacgaataaa
    11881 aaaaatagag gcggagaata cttatcgtat catccgcctt tgtttttttg ttataaaaaa
    11941 cgtcagatta gttatctgct tacatcttca tccatacggg ttctaatgta tttccgtcta
    12001 gatcttggac ttctaatgaa aacatttctt cttcaggcat tcccatatct acttcgtgga
    12061 aagtaccacc attttctttt gcaatttgag caaatttttt tacttcatcc gcattttcaa
    12121 cactaaacga aatcaaagca ccacttgttt ttttattatc agctatttct ttatctttta
    12181 taaatttttt ataaaaatca tgagagagaa gcattatcca aaaagtgtca tcccatacca
    12241 ttgaaccagc ttcttcagta gaaaattctt catttttttt aaaacccagc ttttcataaa
    12301 aagcaacgga acgattgaca tcagcaacag gaaaattaac aaaaaccata ctattcattt
    12361 gtttcgtctc ctttctgttt tgttcgtcta tcatctctta tttaggaaac gctgtcaaaa
    12421 atttagattc atatatagaa accaaaataa aaatttgcat catcaaaaaa gtgaagatgt
    12481 gatagaatga ggactggttc actttcactt aactaataga tggaatttct ttataataaa
    12541 aaagtgaatt tatattgaaa aagaaaaaaa caagtaaagc cggggaatat tccggtatga
    12601 aaggaatgga gagaacaatg accatccaat ggtttccggg acatatggca aaagcccgac
    12661 gagaagtttc tgaaaaaatg aaatatgtgg acatcgtatt tgaattggta gacgcacgat
    12721 tacctttatc ttctcgtaat ccaatgctag atcagatcat tcagcaaaaa cctcgccttg
    12781 ttttattgaa taaagcggat ctggcagatc cacaacagac aaagctgtgg caagaatatt
    12841 ttcgtaaaca aggccatctt gcattagcta tcacggcaca agaaagtaaa ggaattaaag
    12901 gtctagtacc tgcggctaaa gaagcattga aagaaaaacg ggcaagagat gctgctcggg
    12961 ggatcaagcc tcgcgctatt cgggcaatgg tcttaggtat tccaaatgtt gggaaatcta
    13021 cgttgatgaa tcgactagta ggcaagaaaa ttgcacagac aggaaataag cctggcgtaa
    13081 caaaaggtca gcagtggctt cgtttaggta atgagttgga attgttagac acaccaggga
    13141 ttttatggcc caaatttgaa gatgaagaaa tcggcaaaaa actagcgctg acaggcgcga
    13201 tcaaagacca gcttgtccat ttagatgatt tagcgattta cggattagac ttttttgccc
    13261 gatattattc aggaagaatc agcgatcgtt atggtttatc aatcgagcaa gaagaaaaat
    13321 tggcaccgga attactgatg gatattacag caaaacgtgg gtataaagaa gactatgatc
    13381 gtggcagcga attagtcgtg catgatattc gtcaaggaaa acttggacga tacacactgg
    13441 atcgttgcga agaaatggag caaaaaagtg atgactgaat ccatccaaag tatcaaagaa
    13501 cgattgaaaa gcatacagag aatagatgat cctacactag aatcattaag aaatgatcca
    13561 cgcaaaggcg tgcagcaagc actggcttct tttgaacgac gattgaaaaa ggaagcatta
    13621 attaaggaaa aatatgaaga aatgttttgc tttgaaaagc aagggtacgc acaaggtcac
    13681 caatggattg ccggcattga tgaagtagga agaggaccat tagctggacc tgtcgtggca
    13741 gctgcagtta tcttgccgaa aaatgagatc atattagggc tgaatgactc caaacaatta
    13801 tcagagaaaa agcgagaact tctttatcaa caagttcaag aaaaagccct ggcaatcggg
    13861 atcgggatcg ttgatcagca gacaatcgat gatgtgaata tttatgaagc aagtaaatta
    13921 gcgatgatcc aagcagtaga aaaattgtcc attgtaccaa gctatttgtt gatcgatgcg
    13981 atgaccttgg atttgcctat tcagcaggaa aaaataatca aaggggatgc acgatctgtg
    14041 tcgattgctg ctgcaagtat cattgctaaa gtatatcgag accaattgat gaaagaatat
    14101 gacgtgcttt atcctggata tggtttctcg cataatgcag gttatggaac aaaggaacac
    14161 ttagaaggac ttgaacgaca aggaattacg ccaatccatc gtaaaagttt tgcacctgta
    14221 aaaaaatatt tacaataaaa aacagccgct tttacgtatc ttattagaaa gagagacgaa
    14281 aggcggtttt atgatgtatc aaatagaaga aaatttattg aaacttgctt atacaaaagg
    14341 aatcagtagt caaggaaaat gggcacttgc taactggatg atgcagtatc cttataaaga
    14401 aatcggattt gaagacatca ttaagatagg taaaataacc aaacaccggg agctgtttcg
    14461 caaaagttgg caggaaattc acgctaactg gggcaaaatc caatcgaaac agtcgtttat
    14521 cacttgcttt gatcccaaat atccccctca gctgcttcac ttgacctatc cgccaattgt
    14581 actgttttat aatggtgatc tatctttact ttcttgtaac atgttaagcg ttgttggtgg
    14641 aagacacact tctgctttag ccaaaaaaac agtttattat ttactaaaac cagtgataga
    14701 agctggatat gtgatcgtca gtggctgcgc gaaagggata gatacatacg gtcaccaagc
    14761 agcaatctct catggtggac ggacaatcgc agtcattgga acagggatag agcaagtcta
    14821 tcctgctgaa aatcgtgact tgcaagaggt gattgcaaat gatcatcttc ttttgagtga
    14881 atatcctcct caatccggcc cgaaaaagca ttgttttcca atgagaaatc ggattatcgc
    14941 agctttgtct aaaggaacat gtgtctttga agccaagaaa aaaagcggct ctctgataac
    15001 agcacagcaa gcattggatc ttggaagaac agttttttct gttccaggaa atattttaac
    15061 agaacattct accggatgtc atcatttgat ccaagacggt gcagtttgca cggtttcggg
    15121 tgaagatatc ttggcagaat ttaaagaata acaccatact tttcatttgc ttttcttgac
    15181 aaacgttttc tgaatggata tgattagcta cgatttgtat gaatcctctt ttaatagtag
    15241 gaacacgaca atggaaagga gtccattcag taatggcgta taaatattta gtgattgtag
    15301 aatcacctgc aaaagccaag acaattgaga aatatcttgg acgaaactat aaagtaatgg
    15361 ccagtgttgg ccatataaga gatttaccga aaagtaaaat gggtatcgat tttgaaaaca
    15421 attatgaacc ccattatatt tctatacgcg gaaaaggcga tgtcatcaaa agcctgaaag
    15481 ccgcagcaaa aaaagctcaa aaagtttact tggcaagtga cccggataga gaaggagaag
    15541 cgattgcttg gcatttagcg tacctacttg ggttggatct gaaagaaaaa aatcgggtgg
    15601 tcttcaatga aatcacaaaa gacgcagtca aagcagcttt taaggaacca agaacgatcg
    15661 atgtagattt agtagatgca cagcaagctc gtcgtacctt agacagaatc gttggttatt
    15721 cgatcagtcc tattctctgg cgtaaggtca agaaagggtt aagtgcagga cgtgtccaat
    15781 ctgtcgcttt aaaaattatt attgaccgtg aaaaagagat ccgagaattt gttccagaag
    15841 aatattggag catcgacggt aattttaaaa aagctcgcaa gaaattcaaa gcaaatttct
    15901 ggggaatcga cggtaagaaa aagaaattac cagatgcaca aagtgtaaaa gaagtcactg
    15961 ctagaattga tggaacagac ttcgaagtta aaaaagtaga aaagaaagag cgcaaaagaa
    16021 accctgcgaa tcctttcact acaagtagcc tgcaacaaga agctgcccgt aagttaaact
    16081 ttcgaacaag aaaaaccatg atggtagcac agcaattata tgaaggaatc actttgggta
    16141 aacaaggaac agtcggcttg attacataca tgcgtactga ttctacccgg attgccgata
    16201 cagcaaaagc agaggccgca gcatttattg aagatacgta tggaaaagaa ttttctagac
    16261 atgatcaccg aaagatcaaa aatgctcaag gcgcacaaga tgcccatgaa gctgtgcgtc
    16321 caacgagtgt gcttcgtaca ccagatgaac tcaaacaata tttagataaa gatcaattga
    16381 aactttatac attgatctgg tcacgttttg tggctagtca gatgacacca gctattttag
    16441 atacaatgaa agtgacatta gaacaaaatg gtgtcatctt cattgcgaac ggttcaaaaa
    16501 tcaaattcaa aggattcatg caagtgtatg tggaaggtag agatgacggc aaagaagaga
    16561 aagaaaatat tcttccagaa cttgaagaag gcgatgtagt ccaatctgtt gatattgaac
    16621 caaaacaaca ttttactcaa ccaccagcac gttttagtga ggctacgttg attcgtgcac
    16681 tagaagaaaa cggggtaggg cgaccttcca cttatgcacc aacacttgat acgatccaaa
    16741 gacgctacta tgtaaaattg acacaaaaaa gatttgagcc gactgaacta ggagaaattg
    16801 tcaattcatt aatctgtgaa ttcttccctc aaatcgtcga tatccatttc acagcagaaa
    16861 tggaaggaga tttggataaa attgaagaag gcacggaagc gtgggtcaaa gtggttgatc
    16921 gtttctataa accgtttgaa aaagaactga cgaatgcgga agaaaaaatc gaaaaaattc
    16981 aaatcaaaga tgaaccagca ggattcgatt gtgatgtctg tggacatccg atggtgataa
    17041 aattagggaa atatgggaag ttttatgctt gcagtaattt tcctgattgt cggaatacga
    17101 aaccaatcgt aaaagaaatc ggtgtgactt gcccagtatg tcatgaagga caagtcattg
    17161 aacgaaaatc taagaaaaac agactattct atggttgttc ccgtttccca gaatgtgaat
    17221 tcacttcttg ggataaacca gtgggcagaa attgtccaaa atgtgacgga tatctggtcg
    17281 agaagaaagt caaaggcggt aaacaagtag tctgtgtaaa tggagattac gaagaagaca
    17341 tccaaaaata atagaaaaga ggttctttca ttgaaaatgg taaatgttgt tggagcaggg
    17401 cttgccggaa gtgaagctgc ttggcagatc gcacaagcag gagtccctgt ccgtttatat
    17461 gaaatgcgtc cagtcaaatc gactgaggcg catcacacaa gtaattttgc tgaactagta
    17521 tgttccaatt cattaagagg aaacagtttg gctaatgcag tagggttatt gaaagaagaa
    17581 atgcgccgat tgaattcggt agtaatcact tcggcagatg aaacagcagt gccagctggt
    17641 ggtgccttag ctgttgaccg cgattctttt tctgaaacaa ttacccgaaa agtcaaagag
    17701 catccattag taacagtgat aaacgaagaa attactgaaa taccggaagg aatcaccgta
    17761 gtagcaacag gacctttgac ttctcatcca ttagcagaaa gcatcaaagc attcaatggt
    17821 tcagatggtt tttatttcta tgatgcagct gcaccaatcg tagacaaagc tacgatcgat
    17881 atggataaag tatatttgaa gtcccgctat gacaaaggag aagcagctta cttgaactgt
    17941 ccgatgacag aagaggaatt caaagctttc catgaggcac taatcaatgc cgaagtggca
    18001 gaacttaaat cttttgagaa agaaaaatat tttgaaggat gtatgccaat tgaagtaatg
    18061 gcacagcgag gattcaaaac gatgcttttc ggacctatga aaccagttgg attggaagat
    18121 cctaaaactg gcaaacgtcc ttatgctgtt atccagctgc gtcaagacaa tgctgcagct
    18181 tctttataca acatcgtggg ctttcagact cacttgaaat ggggcgagca aaaacgtgtt
    18241 ttccggatga ttcctgggtt agaaaatgct gaattcgttc gctatggtgt gatgcaccga
    18301 aacagcttta tgaattcgcc agaattgctg aaaccgactt accaatcaac gaaacgcgaa
    18361 gatctgttct ttgcaggtca gatgactggt gtagaaggct atgttgaaag tgcagcgagc
    18421 ggactacttg ctggaatcaa cgccgcacgc ttagcaaaag aaatggaacc agtcgagttt
    18481 ccacaagaaa cagctattgg aagtatggct tactacatta ctcatgcgga aggaaaacat
    18541 ttccaaccga tgaatgccaa ctatggtctg tttcctgaac tgccagagcg cattcgagac
    18601 aaaaaagcaa gatatgaagc aattgcacaa cgagctttaa aagctaatga ggcaataaaa
    18661 acagaattag aaaaaactgc aatcccaaat gagtaaggaa actccatgaa gagggtgaga
    18721 cggatagtct cgctcttttt cttgcgtttt tcttaagaat ttctcaaaca aaatgtgagg
    18781 aattgcgcca attgtgaaca aacttagaaa tattggttaa attctgacaa tttatttgtc
    18841 tttttataaa cgctgtgcta aattattctc tgggacaaaa ggaaggtgag aaaatgacag
    18901 aagccacgtg ggaacaaaaa tttttgcgtt atttgattgt cgaaagagga tattcagaaa
    18961 aaacgaaaga agcatatgaa gaagacattc tccatttcaa acattttttg gaggaatctg
    19021 gagacgctga tctgctgaag gcggaatatt ttacggttcg tgtctatttg agtgcattag
    19081 ctgatcatcg tcctagctat agcagaaatt ctatcagtcg caagatagcc agcctacgtt
    19141 cgttttatca gtatcttctc aaagaagaag tgataaaaga aaatccattt tcttacgttc
    19201 atctcaaaaa gaaaaatttg agactgccac gtttttttta tgaaaatgaa atgcaagcac
    19261 tttttgacag cgtagcagga gatagtcctt tggatttgag gaaccgcgct ttactggaag
    19321 tcctttacgg gtcaggcatc cgtttaagtg agtgtagcag tttgtcggta tcagacattg
    19381 attttgattc agaggtcatg ttgatccatg gtaaagggaa caaagagaga tatgctcctc
    19441 taggttcttt tgctcaagat gctctgcaag aatatttcag ggaaggccgc caggtattga
    19501 tgacaaaata tcacgaagag catgatatcg tttttgtgaa tcatcatgga aaaccaatca
    19561 cgcctactgg aattgaatat gtcttgaatc aaatgatcaa aaaaagcagt ttggatagtg
    19621 atatccatcc tcacatgctg cgccatacat ttgctactca tttattaaat aatggggcag
    19681 atttgcggac agtccaagaa ttgctaggac atgccaattt atcgactacc cagatctatg
    19741 cccatgtaac aaaagaaagt ttacaaaaaa actatcgttc tttccatcca agagcgtaaa
    19801 aataaggaaa agaacaaatt taggaggaaa caaacatggt cgaatcacca tttcattcaa
    19861 ccactatctg tgccgtcgaa aaagacggga aatttgctat ggctggagat ggccaagtaa
    19921 caatgggtga atctgttgtc atgaaaggca ctgcaaagaa agtacgacgt atctacaatg
    19981 gagaagttgt tgtaggtttc gccggaagtg ttgcagatgc gtttacttta gaagaaaaat
    20041 ttgaaggcaa actaaacgaa tataacggga atctacaacg cgcagctgtc gaattagctc
    20101 aagaatggcg gacacagcaa tctatgcaaa aacttgaagc gatgctgatc gtaatgaatg
    20161 ataaagaaat gcttcttgtt tcaggtacag gagaagttat cacaccagat gatggtatct
    20221 tagctatcgg atcaggaggg aattttgcgt tggctgcagc ccgagcaatg aaaaactatg
    20281 ctcaaaacga catgagtgcg aaagaaattg cagaaaatgc gttaaatatt gccgcagata
    20341 tctgtatctt tactaatcat aatattatcg tagaagaact gtaagaggtg agtagatatg
    20401 tatgaattaa aacaaacacc aagacaaatc gtaagtgaat tagatgaata tatcgtagga
    20461 cagcacgcag caaaaaaatc tgttgccgtt gctttgcgta accgctatcg ccgtttgcag
    20521 ttagatgaaa aaatgcaaca agatattaca ccaaaaaata tgctgatgat cggacctaca
    20581 ggggtcggta aaacagaaat cgcacgacgt ttggcaaaaa tcgtcaatgc accatttgtc
    20641 aaagtcgaag caacaaaatt tactgaagtc ggttatgtcg gaagagatgt agaatcaatg
    20701 gttcgggatt tagtagaaaa tgcgatccaa atcgtagaaa aagagcagta cagccgtgta
    20761 tacacaagtg ctaaaaaaaa tgcagaaaaa cgtttggtaa aaatcttggt acctggtatc
    20821 aaaaaagaac agaaacaatc cactaatcaa tttgaacaaa tgatgaatct ttttaatgct
    20881 agtcagcaaa ataccgctga accgcaagaa gaagtgacag aagatattcg aatcaatcgc
    20941 cgtacagtct tggaacaact acaaaagggt ttactggata gtcgtgaagt aaccattgaa
    21001 gttgaagacc aaaagaaacc tgcaccaatg atgaacaatg gattggagca aatggggatc
    21061 gacctaaatg aaactctagg tgctttgaca ccgaagaaaa aagtggaacg gacggtaaca
    21121 gtcaaagaag ctttagagtt attgatcaag gaagaatcag caaaattagt caaggatgct
    21181 gatatccata gtgaggcaat caaattagcg gaagaaagtg gaattatttt tatcgatgaa
    21241 atcgataaga tcacttctaa atcacagcaa tctggagaag tatccagaga aggcgtccaa
    21301 agagacatat tgccaattgt cgaaggttca caagtaaaca caaaatacgg gatcatccaa
    21361 acagatcacg tcctattcat tgcttcagga gctttccatt tgtctaaacc aagtgatcta
    21421 attccagaac ttcaaggacg cttcccgata cgggtagaat tagatgattt gacagctgaa
    21481 gattttgtga agattctgac cgaaccaaat aatgctttag taaaacaata cgtcgcgttg
    21541 atcggtacag aaaatgtgtc agttacgttt acaaaagaag caattgaacg gatcgctcaa
    21601 atcgctttcg atgtcaaccg tgacacagat aatatcggcg cacgcagact gcataccatt
    21661 ttggaaaaac tactagaaga tctattattt gaagcaccag atatgcaaat gggagaaata
    21721 acgatcacag aagcatatgt ggatgacaaa cttggctcaa ttgcggcaaa tgaagattta
    21781 agtcgctata ttttataaaa aatcggagga cgacaatgac agacttgcta acgaaaaccc
    21841 gcaagataaa cacacttttg cagcaaaaga atacttttga catgcaagca gatttgcctt
    21901 acgataaaat ggctgtcaca ctaggtggta ttcttgacag caacacctat atcataggaa
    21961 gtgacggagt attactaggt tataatgaac gtcacgatgt gaacaatgaa cgaatcaaaa
    22021 caatgtttgt tgagaaacaa tttcctgaat cttatactga tacagtggca cagttgatga
    22081 aaactgaagc taatatccca attactagtg atattactgc atttccggta gagtcaagag
    22141 agaaatatcc atttggtctg acgactgtcg ttccgatctt tggagctggc gaacgtttgg
    22201 gtacgattat cttatctcgt atggaacaat cgtttgcaga tgacgatcta gtcttagcag
    22261 aatatggagc tacggttgtc ggtatgcaga tcctttatca gaagtctcga agcatcgaag
    22321 cagatgtacg gagtgcaacg gctgtccaaa tggcaatcaa cacattatct tatagcgaat
    22381 tgaaggctgt acaagctatc tttgaagcat tggatggaga tgaaggtcgt ctgactgctt
    22441 ctaatattgc cgatagtatc ggcatcactc gttctgtgat cgtcaatgct ttacgaaaat
    22501 tggaatcagc tggaatcatt gaatctcgtt cgttaggcat gaagggaact tatttaaaag
    22561 tattgaattc ccgttttaaa gacgagttag caaaacacag ttattagaag taaggggact
    22621 ggggcagata gaaatgtttg ttccagcctt cccattttaa aaagtaagtc gaagttggag
    22681 gaatggcaat gactgttatt attcaaaatg accagctgat cgccgaaatc gctgaacacg
    22741 gtgcggaatt gatcagtctg aaatcaaaag aacatggttt agagtatatc tggcaaggtg
    22801 atccagcgta ttggggcaga catgcaccgg ttttattccc ttttgttgga cgtttaaaag
    22861 atgatcagta tgtttatcaa gggaaaacat atcaaatggg gcaacacgga tttgctcggg
    22921 atatggattt tgaagtcatt gaacatggac aagaaatggc tagtttcatc ttaaggagta
    22981 cgccggagac attagaaaag tatccatttg attttgaatt agtgatcagc tatgaattag
    23041 gaggagacgg catcacggtt cattatcaag tggcaaatac cggtgaaaaa gaaatgttct
    23101 tttctatcgg tggacatcct gctttcaatg tacctcttga agaaggattg tcatttgaag
    23161 atttctatct ggcattttct ccattgaaat caagattacg cctaccattg aaaggcccat
    23221 tcatcgatat ggatcaaaag acgttaggtc agacaaatac gaatctggct ttgaatcgtg
    23281 aactttttga gcaagatgcc ttggtttttg aaacaagggg tctaaatgcg tacgccattc
    23341 gaagtgaaaa atcttcccat agcgtaactt taagctataa agatatgcct tatgtaggga
    23401 tctggtctcc ttatccaaaa gaagcgcctt tcgtttgtat cgaaccgtgg tgcggaatcg
    23461 ctgacacggt gaacagtagt ggaaacttga tggaaaaagt agggatcaat caactaggtg
    23521 cccatgaaat cttcaagaca aaatattcca tcacagtgaa gtaagaggtt gtgaccgaga
    23581 agttagcagg gaacaccgtt taccaaggtg tgtaaaaaag ctatcctgta agtaataagg
    23641 gagtgtgaca tcgattt
//
LOCUS       DAFEKH010000043        23449 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.044, whole genome shotgun sequence.
ACCESSION   DAFEKH010000043
VERSION     DAFEKH010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23449
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.044"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(459..1088)
                     /gene="udk"
                     /locus_tag="LP386_001941"
     CDS             complement(459..1088)
                     /gene="udk"
                     /locus_tag="LP386_001941"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HBL1919176.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1172..1867)
                     /locus_tag="LP386_001942"
     CDS             complement(1172..1867)
                     /locus_tag="LP386_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HBL1919177.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1880..2596)
                     /locus_tag="LP386_001943"
     CDS             complement(1880..2596)
                     /locus_tag="LP386_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HBL1919178.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2926..3531
                     /locus_tag="LP386_001944"
     CDS             2926..3531
                     /locus_tag="LP386_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HBL1919179.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3856..4179
                     /locus_tag="LP386_001945"
     CDS             3856..4179
                     /locus_tag="LP386_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HBL1919180.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4361..5731
                     /locus_tag="LP386_001946"
     CDS             4361..5731
                     /locus_tag="LP386_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBL1919181.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5861..7162)
                     /locus_tag="LP386_001947"
     CDS             complement(5861..7162)
                     /locus_tag="LP386_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBL1919182.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(7392..9350)
                     /locus_tag="LP386_001948"
     CDS             complement(7392..9350)
                     /locus_tag="LP386_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HBL1919183.1"
                     /translation="MAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9527..9793)
                     /locus_tag="LP386_001949"
     CDS             complement(9527..9793)
                     /locus_tag="LP386_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBL1919184.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10303..12429)
                     /gene="pnp"
                     /locus_tag="LP386_001950"
     CDS             complement(10303..12429)
                     /gene="pnp"
                     /locus_tag="LP386_001950"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HBL1919185.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12617..12886)
                     /gene="rpsO"
                     /locus_tag="LP386_001951"
     CDS             complement(12617..12886)
                     /gene="rpsO"
                     /locus_tag="LP386_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HBL1919186.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13137..13700
                     /locus_tag="LP386_001952"
     CDS             13137..13700
                     /locus_tag="LP386_001952"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBL1919187.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(13953..14474)
                     /locus_tag="LP386_001953"
     CDS             complement(13953..14474)
                     /locus_tag="LP386_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HBL1919188.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14477..15319)
                     /locus_tag="LP386_001954"
     CDS             complement(14477..15319)
                     /locus_tag="LP386_001954"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HBL1919189.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15312..16037)
                     /locus_tag="LP386_001955"
     CDS             complement(15312..16037)
                     /locus_tag="LP386_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HBL1919190.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16213..16509
                     /locus_tag="LP386_001956"
     CDS             16213..16509
                     /locus_tag="LP386_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919191.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17077..18669
                     /locus_tag="LP386_001957"
     CDS             17077..18669
                     /locus_tag="LP386_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBL1919192.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18682..19422
                     /locus_tag="LP386_001958"
     CDS             18682..19422
                     /locus_tag="LP386_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBL1919193.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            19590..20939
                     /locus_tag="LP386_001959"
     CDS             19590..20939
                     /locus_tag="LP386_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1919194.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(21067..21657)
                     /locus_tag="LP386_001960"
     CDS             complement(21067..21657)
                     /locus_tag="LP386_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBL1919195.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVIVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            21804..23156
                     /gene="brnQ"
                     /locus_tag="LP386_001961"
     CDS             21804..23156
                     /gene="brnQ"
                     /locus_tag="LP386_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBL1919196.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         6710 a         4728 c         4468 g         7543 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaac agttggctgg tgactgttca aaaagcagaa tccttgcttt
      421 tcaaacggtc gcagtccgtt caactgtttc gctgcgcact atttatggtt taagaaacta
      481 gctacttttg ttgtaatcaa atcaatagca acgtggtttt ctccgccttc tggaacaatg
      541 atatccgcat agcgcttcgt tggttcgata aattgatgat acatcggttt aacaactgtc
      601 aaatattgtt cgatcacgga gtccaatgtg cgtccccgtt cttccatatc ccgtttgata
      661 cgacgaatga tacgaatgtc atcatctgta tctacgtata ctttgatatc catcaagtca
      721 cgcagacgtt cgtcttctaa aatcaggatt ccttctagaa tgatcacttc ttttggttcc
      781 tgaatgatcg ttgcctgact tcttgtatgc gctacatagt catacacggg tttttcaatg
      841 gctttatagt tcagtaagtc gcctacatgc tgaatcagca gatcattatc aaaggcaaat
      901 gggtgatcgt aatttgtgtt caatcgttct tcaaaactca aatggctctg atccttgtaa
      961 taagaatctt gttcaagcat catgatggaa tggtccggga agttgttgaa aatcgcacgg
     1021 ctgacacttg tctttccgct tccggatcca cccgtcacac caatgataat tggcttgctt
     1081 tttgtcattg actaaaacct ctttcgtatc cgttttttca ttctaatcta ttatagcgaa
     1141 aaaacacgaa aatgctatat ttttctgaaa attaatcctt ttcaatttcc aataatgaat
     1201 aaagttcctc taatgaatcg attcgataag taggctggat ttcttcgatt tctggtaatt
     1261 tatttctatt gaaccaaatc gtatcgatcc ctgccatatt tcctcctttg atatcagaag
     1321 tcaaagaatc accaatgatc acagtttgct ttttatcaaa attaggaatg tgggaaaaga
     1381 catgatcaaa aaattctttc atcggctttt gcgctccgac agcttctgag acaaagatat
     1441 ccttgaagta atcaagcatt cctgcatctg ttaatcgccg atgttgcgtg tgcgacacac
     1501 cgttcgtcac aatataaaga tcagcatgcg gatggacctt tttcaggatt tctagacttc
     1561 ctggaacaag atcatgacct tggttcaagt agtggcggta gcgtttttcc atttgatcac
     1621 tatctactgt tttcccaaat tgctggaaaa gtaacccaaa acgactgcct attatttctt
     1681 ctcgtgatag tctgcctttt tcaaactcct gccataaatg atgattcaaa gccttatagc
     1741 tggtttcgat ttctggtgtc aatgtgattc cttgttctgc aaacaaagca cttaaagcat
     1801 tggcttcagt taattgaaaa tctaacaatg tatcatctac atcgaacaat aaagttttat
     1861 atttcatctt tttgacctcc tatttaaaat aaatacttaa ctttttcatc tctgctaatg
     1921 tcaacgatcg atactcgcct actcctagct gttcatctaa ttccaatggt cccatgctta
     1981 gccgtttcaa tgcggtcact ttctttcctt gggctaagaa catctttttg acttgatgga
     2041 attttccttc ttggatcgtc aataaaaccg tactttggtg cttgtctgct ttgagtattt
     2101 ttaaatcagc cggcttacat tgatacccat cagcgaatac gattccattt tcaaatgctg
     2161 ttacgtctgc cggtgtcacc ctttcgttca caactacttg ataagtcttt gaaacctttt
     2221 tttctggaag tagcatttca tatcccaatt gtccattcga agtgatcagc aatagtcctg
     2281 ttgtatctct atctagtctt cccactggat ataatggttg gaaacgatcg gcacttgcaa
     2341 tcagatcgat tactgtcgtc ttttctggat ctgatacagc tgtaacagct ttttcaggtt
     2401 tattgagaag ataataggac tcatttgttt ctaagtgttc acctgctact tcgatttgat
     2461 gcagtaaact atctacattt cgattttgtc gaaattcgac tgtgccatct atcatcactt
     2521 gcttcaaagc aaacagccgc ttcatttcct tgcgtgtcgt ttctaatttt tcttctatta
     2581 atttatctaa acgcatgctg tttcctttct tattactact aattaattat accttgaata
     2641 ttcttgcttg caaatacatc atcatagtta ttccttgact taattaacag ttcacgttac
     2701 ggttaaatag taaagtgaat tggatttctc atacacagcg taatgacctg gtggagaaaa
     2761 gttgaatcct gactttctaa ggggagatgc gcgcatctct ccttttgcgc ttttttaagc
     2821 gccctgcctt cgatgatgtg cacgagatta gcctttagaa ttcacttaaa taaaatctgt
     2881 ccgttaccaa agcagacagt cacattttaa ggaggaattt tggttatgtc agtatcatta
     2941 gaagtaagta aaagagaagt acgtccccgt tcattaagaa acaaacttcg tcacgaaggg
     3001 aaagttccag ctgttgttta tgggtataaa gtagaaagta cccctatctc attcgatggt
     3061 ttgacactaa gcaaattgtt gcgtgaacat ggagcgaaca cagtcatcac gatggacatc
     3121 gatggacaaa aagtcaatac attggttcac aagatccaaa cgaacacttt taccaatcat
     3181 ttcgaacatg cagaatttct atctgtaaac atgtcggaag aaacagaagt cgaaacagaa
     3241 gtcgttcttg ttggcgaatc agtgggtgct aaatctggtg gagtgttagc tcaaaacttg
     3301 tatacagtag tcgtatctgc tacaccagac aaattgcctg aacgaattga agttgacgtg
     3361 acaaacttgg aattaggtga ttctattaca gtagccgatc ttccaaaaaa cgacgattac
     3421 aaattcgtga ccgacagtga agagcaaatc gctgctgtag tcgctcaaag tgaagaagaa
     3481 agcacaggtg aaggtggcga accagaagtg atcggttcaa cagaagaata atactgaaac
     3541 aatcaggtgg tgttagaagc ggcgggtcag cagcttttaa cacgcctttt ttatttctaa
     3601 tcgtttattt tcatatgggg cttccacttt tgtaaatggc tttacaaacg aaaaatccta
     3661 atttaccaag cttttcctcg catactttta tcgtaccttt ataaaaattt atactttgaa
     3721 aaaaagtatt caattattgt tgcatttttc ctgattcttt attagaatga accctcgttg
     3781 aagtaagtat ttctagttta tcctaggatt aattataaaa ataaaacatt cgttgattcg
     3841 aaggaggtta aacagatgtt tgaaagtttt gatagcagcc gcaaccgtta cgcttcagtt
     3901 ggtgtcgtat caagtttgcc agatgaattg attgacagta tatggtttat tattgaccta
     3961 gatcttaagg gagtcattcc attagaaaat atattaacct ttgatttgat cgaaaatcgt
     4021 ggaaaagtga cgatgcattt ttctcaagca ggaagcaatg tggaaatgga tattgatttg
     4081 ccgtttgcct attcgaacca atttcctgct caagtatacg cctatgatga cggtacgaga
     4141 gaaacgatcc ttttaccaag tgagattaga caatattaag gtgatagata aacgtggatg
     4201 tcccttattt tacagaccag gccaagttgt tgattctttg actcaattct tggcttcttt
     4261 ttatggagtt tcataaatta tcattgattt ctaattggta ttctcaggat aaacgctata
     4321 tactactaac taaattttaa agatataagg agtttaaaag atgcgcgatt taacaaaagg
     4381 aagccccgct aaactgattt tgatgttcac tgttccttta ctgatcggaa atgtttttca
     4441 gcagttctac aatatgatcg atatgatcat cgtgggtcag acgctaggta aaaatgcgct
     4501 ggcagcggtt ggtgcaactg gaagcctgac atttttgatc attggctttg cccaaggttt
     4561 aacagctggt ttagccatta ttaccgcaca acgttacggt gcaaaagatt atcggggtct
     4621 gaagaaaagt tttgctgcta gtgttgtcat tagtcttgtc gtcactgtga ttttaactgt
     4681 cctaagtctc ctgtttattc gtccgatgct tcaattgatg caaactcctc ctgaaatact
     4741 tgatcaagca caaacattta tttcaattat tttattaggg atctttgcat cagtcagttt
     4801 caatttgctt tctaatgtca ttcgcgcact tggtgacagc cgcacaccac tattctttct
     4861 gatcattgcg gtcatcatca acgtcgtact tgatttgatc tttattatct attttggcat
     4921 gggtgtggaa ggtgcagcta ttgctacagt aatcgcacaa gtttcttcca gcgtactgtg
     4981 tctagtgtat atcaagaaaa aaatgccttt gttacagtta cgcaaaaaag atttcaaatt
     5041 tgaaaaagaa gagtttgctg tacacctaaa tgctgctttg ccaatggcgt ttcaatcttc
     5101 gatcatcgct gttggtgcta tcgtgttaca agcagcacta aatagtctag ggacagatgt
     5161 cgtagctgct caagccgctg ctggtcgtat cgaccaattt gcaaatcagc cgatgatgtc
     5221 atttggtatt gcaatggcaa ctttcactgc acaaaactat ggtgcgaaag aatatggccg
     5281 aatcttgcaa ggggtacgtc aaactttact gatgagtgtc ggatttagtc tcttagcagg
     5341 tgctatcgtc attttcttcg gtcatttctt tgttcaattg tttgttagcc catcagaaac
     5401 acgtgtattt gaattagcac aaacctactt caatatcaat gggtctcttt actggatctt
     5461 agcagtcctg ttcattttac gctacacact tcaagggctt ggacaaagca agatccctac
     5521 gatcgccggt atgatggaat tgcttatgcg ttcttttgca gctatcgttc ttacaggaat
     5581 gtggggatac ccaggagcag cagcagcttc tcctttagct tggatcggtt ctgttgccgt
     5641 gttgctttac tcttatatgc gttcgatgaa acaattgaaa cacatgggtg aagaggaaca
     5701 tttcacatta gaacatgcag aagcaagata gccttgatta aaagaaatcg ttgcggctaa
     5761 aaatgaaaac ttttattgaa aatatcttct tcgtttaccg aaaacaggtt ttttagataa
     5821 caaaaaggct gtgacaaaaa atgtcacagc cttttttctt ttattctatt tttctttccg
     5881 tggactctac tttgaaataa tcgatatgtg catgctggta ttctaatacc gtgaaacgga
     5941 atgatgcaat ctcaatgatt gttcctgctt ttatttcttt atatcggcta gaagcaaagc
     6001 ccgcaagtgt agtaaaattc gtttcttcaa actctggaat ctctacatga aaataacgct
     6061 ggaaatcatc taatgttagt ttgccggaga tgatataaga gccatctgac tgttccgcta
     6121 tcaatgcttc gtccaaatct gtctcatctc ggatttcccc gacgatttct tctaaaatat
     6181 cttcaatcgt cactaagccg cttgtccctc cgtattcatc ttttaagata gcaatatgct
     6241 ttcccttttt tcgcatgatc gtcaataatt tttttatagg gatcgtttca gttgttacga
     6301 tcggctcttc aatcaactgt tctactgtca gctggtcatc tttataagat tgcttgatca
     6361 aatctggcaa ggtgacataa cctaaaacat tgtcttttga ttctaagata accggatagc
     6421 gagtatgtcc ttgttcaatc gaagctttta tcgcttcttt gacggtttct gaagcttcga
     6481 atacttgcat ggacgtacgg tctacttgta tatcttttgc caaggtatca tcaaattcaa
     6541 acacgttttc caaataatga tattcttctt tggtcaactc tcctttttca taagaattca
     6601 atgcgactaa tgtcagctct tcttgagaca atgtctcttc tccttcagat acgagacgca
     6661 cacctaatag cttccctagc cctgcagctg aatgattcaa tacccaaata aaaggaaaca
     6721 ttactttata aaaataatga agtggtttaa ctacgaacaa gacgaccttc tccgtattga
     6781 cgatactata gctcttagga agcagttcgc caataaccac atcgatatac gtaactaaaa
     6841 taaatcccag cgccacagag attgtactgc taatagccga actaaaaggt agtttaccga
     6901 tcactggttc tagtaaagcc gcgacagatc cttcaccgac ccacccgatg atcaaaccgg
     6961 ttagcgtaat tcctaattga ctagctgata aatagttatc taaatggtgt gtaacatgaa
     7021 gagctagctt ggcgttcttt acattttcct tttctagttg ttccaatctt gatcgtctga
     7081 ttttcactaa agcaaattca cttgctacaa aaaatgaagt aattgcaatc atcaaaaata
     7141 aaataatgaa attgataacc atattctccc gcctttctct ttttctattg tacccttttt
     7201 ctacaaaaag attgaaaata atgcgtattc atatttagga ataaaaaagg agatgcggca
     7261 tttttcagcc acatctcctt atcacttcaa aatcattgcg ttacttgttg ctaaacagct
     7321 ttttcatgac ctctgataaa cggtgttcaa gtagctgaca ttcgacatta gttcaggtca
     7381 aagcgctact ttcacaaccg ctctttcaac catgttttcc gagtatttcc aatgataagc
     7441 ggaacagttt catgttttac ttcgctgtac tctagcccaa accatgtttc tggcgaggta
     7501 gcgatttttt tgattgccag ttttgcctgc atgatttgac gttgccattt tcctagagtt
     7561 gtcacattgg aaactacttc atcaatcagg acaaattgga aatcgccaac ttctcgccct
     7621 ggtgtcagag agtatctttg tggctgtttt ggcaaacggc cttgtttcat caaatcatgg
     7681 atgacttggc gaacatatac gttgatttcc tgttggaccc tgaaacctaa gaacagattc
     7741 acttggacaa taaaatcagt gtccatcata tctacttgat attctttcgt atatggctca
     7801 tccgtcactt ccacatgaac aaaccaatag actcgtgctc ttttaggccg tttatctaaa
     7861 atcgaataga tgaactgtcg gccaacttta tcttcagcca tatcaggaac caagaagacc
     7921 acatttgtct gatagattgg taaagaagta tcatcacgta attctctaag ctgcgggata
     7981 taatctctca aagacacatc ctcggttgac gattcgcgaa taatgttccc ttgttcccaa
     8041 ataaacatca cgactaagat gatcaaacca atcagaacgg ctacaaaacc gcctcggaag
     8101 aatttgacaa cacttgagat aaagaaaacg acttctatcg caccgaagaa aaaggtaact
     8161 aaatatgcaa gccaacgaga atgcccattt tggataagat aaaagtaaag cagtgctgtt
     8221 gtcatcaaca tcgtcacagt gatcgataga ccgtaagcag cttccatatg atgagacgtt
     8281 cggaatgtga caaccactag agaacaggcg atccataaaa tcagattgac tgctgggata
     8341 tacatttgcc cgatactgtt cccaggatac atgatcttta accgaggcag cagtttcaac
     8401 ttgattgctt ctgaaactag cgtaaacgaa cctgtaatca atgcttgcga agcaatgact
     8461 gcagcgactg ttgcaaaagc aacgccgatc acgatccaac tttgaggcat catttggaag
     8521 aatggattca ggttcttgat ttgctgtgct tcagggtttt gataaacatt caacaaccac
     8581 gcagcctgcc caaaataatt gataaccaaa caaattttga cgtaaggcca gctcagacga
     8641 atatttcgtt tgccgacatg tccaagatcg gaataaagcg cctctgcacc tgtcgtagcc
     8701 aggaaaatat ttccaagaat gaacaagcct aatttgttat ctgcactaaa aagcagctgg
     8761 atagcataat aaggattcag tgcacggata actgtccagt cttgactgaa gttcattaat
     8821 cccattacgc ctaaaaaagt aaaccaagcg aacatgattg gtccgaatgc ttttccgaca
     8881 atatctgtac caaagcgttg gaccatgaat aaaacaaaaa taataactaa agtgataatg
     8941 acgatcacgt tctggttatt accgaaccgg tcaaaaaact gcggaattcc tcgcaagcct
     9001 tcaatcgcag tcgttaccgt cacagcaggg gtcaataccc catctgctag taaggcagct
     9061 cctccgatca ttgcaggaat gatcaaatat ttcccacctt ttcggacaag tgtgtagagt
     9121 gagaaaattc caccttcacc atggttatct gcattcaatg caatcacgac atatttgatt
     9181 gttgtcagta gagtcaatgt ccaaaaaatc aatgagactg atccgataac aaaatcagga
     9241 ttgattcctg acaatccgcc attatcttca acaatcgatt tcataacgta aagcggactt
     9301 gtcccgatgt ctccgtagac gactcccatc gctacaagca ggccagccat tgatatcttt
     9361 ttggtattgt gcgttgttgc cacgtttttc cctcatttct tgttatatgg atatccttta
     9421 ggtaagcttg aatgatagat gatattctta tccatgacac ccgctttcct aaattgcttc
     9481 taattatcca agtaacacac tgaagtgtca acttatttga ataaaattat tctttctttg
     9541 gacgttctct gatacgtctt gccacaaatg aataaagagc aaggcaaaaa attgcaccca
     9601 ataatgctgg tatcaaataa aaaccgccga gttccggtcc cagtggtcct agtaaaaatt
     9661 cgccgagcca actacctaaa aaaccgataa tgatatttcc agatacgcct cccgggactt
     9721 cctttcctaa aattgcgcca gctatcaaac ctaatatacc gccgataaat aacgaccata
     9781 aaaaattcag catctccttt ccctccttta tccatatttc tcacttttat tttacgcttt
     9841 attcagaagg actccaaaaa tatgcgccaa gaaactccag aaaaaaagaa gttgtaacaa
     9901 aagtgttcag cttatttccg tagaagctgc ttctggaaca ccgtgaatca gaggttgtga
     9961 aatcagcggt ttgacctgag tattagagaa acaaacggaa aaatagttcc tcatattttg
    10021 ccgttttttg agctaatatc gagggacagc tgattgaaca tcgtttattg gagaggttgt
    10081 aaaaaagctg ttctgcatca agtaataaga acagccaagt aaaaacagct cctaatgttt
    10141 ttaacttggc tggacttatt accgcagatg caagcttttg aacaccgttt attcgaaaaa
    10201 aaaggactgt gacacggctt ttgtcacagt cccctttttt cgaataatta ttgtccccct
    10261 gtcaccttca cgatcacaag tacattattc ctatgaatta aattattttt cttcattttt
    10321 cgttgaacca tcttcgttca acattgcttt tcttgacaga tttacgcgtc cttgtttatc
    10381 gatttcagtt actttcacaa ggatctcatc acctagttta acaacatctt cgactttatt
    10441 gacacgatcg tttgctaatt gggaaatatg gacaagtcca tcttttcctt tgatcaagtt
    10501 gacgaatgca ccgaattttt cgatacggac aactttccct agataaactt caccaacttt
    10561 gacttctttg gtcaaatctt cgatgatctt gatagctttt ttgatcattt ctgcatcagc
    10621 tgaagcaata cttacttttc catcttgatc gatatcgatt ttcacaccag tttcatcgat
    10681 gattccgttg atcgtatcgc cgcctttacc gataacatct ttgattttag caggttcgat
    10741 ctggatcatt tcgatttttg gtgcatattg gcttaattct tcacgtggag cagcaatcgt
    10801 tgaagtcaat tcttctaaga tttccatacg tgcttgtttt gcttgagtta atgcttcagt
    10861 taggatttgt tctgtgattc cttgaatctt gatatccatc tgtaaagcag tgataccatc
    10921 ttttgtaccg gcaactttaa agtccatatc gccaagatga tcttccagcc cttggatatc
    10981 agttaggatc gtatagtttt caccatcaga aacaagtccc atcgcaatac cggcgactgg
    11041 cgctttgatt ggtacacctg catccatcaa tgctaatgtg ccagcacaga tacttgcttg
    11101 ggaagaagaa ccatttgatt ccaatacttc tgctactaaa cggatcgtat aaggaaattc
    11161 ttcttctgaa gggattactt gtgctaacgc acgttcacct aatgcgccat gtccgatttc
    11221 ccgacgccct ggagagcctg cacgtcctgt agaaccaaca gaaaattgag ggaaattgta
    11281 gtggtggatg aatcgtttgc tgacttccac ccctaaacca tcaatgattt ggtgctctcc
    11341 tagaggtgcg agtgtacaag ctgataaagc ttgtgtttgt cctcgtgtga acaaacctga
    11401 tccatgtaca cgtggcaata agctgacctc tgatgacaat ggacggattt catccaattt
    11461 acgcccgtca ggacggatct tatcgatggt gatcaattca cgtacgacat ctttttcaag
    11521 atcttctgtg atttgtttaa cttctttcaa caagtgatct tcatcttcat gacctgcaaa
    11581 tttctcagca taagcttcgc ggatatcgat cttcacctgc tcgatattat cttcgcgagc
    11641 aagtttttct tcagtcatta ctgctgcttt cattgtagcg taagaagcat caaagatttc
    11701 ttttttcaat acttcatcaa cttgcagtaa agtcacttcc attttttctt tccctactgc
    11761 ttgaacgatt tcttcttgga aagcaactaa ctctttgata gcgtcaaaac caaacagcaa
    11821 tgcaccaagc atgtcttctt ctgaaacttc tttcgcgccg ctttcaacca tattgatggc
    11881 ttgtttcgtt ccggcaacag tcaattcgat atctgtttgt tctgcttgtt ctactgttgg
    11941 attcaagacg tactcgccat ttacacgacc aacttctacg cctgcgattg ggccgtcaaa
    12001 tgggatatct gagattgata gtgctaaaga agaacctagc attgctgcca tagctggcga
    12061 gcagtctgtt tctacactca tcacgatgtt cgttacttgg acttcattac ggaagccttc
    12121 tgcaaacatc gggcgaattg gacggtcgat caaacgggca gtcaatgttg cttccgtact
    12181 tggacggcct tctcgtttga tgaaacctcc agggattttc cctgctgcat acattttttc
    12241 ttcataattg atcgttaatg ggaaaaagtc tgtatctttt gcttctttag aggccacagc
    12301 tgcacttaag actactgtat ctccataacg gactaaaacg gctccgtttg cttgttttgc
    12361 tagctgaccg acttcgattt gtaagggacg gccgccccat gtcgttttga atacttgttt
    12421 ttctgacata acttctcctt ttccttctcg tgaaagcaag acgctactaa acaaatgaaa
    12481 actgccgaaa gccgtctttt gagcagcttt catttggtta gtaggagtcc atctagcttg
    12541 atcacggaat tttacttaat tgatatacga gtaaaaaaag tgagattcat gtgaatccca
    12601 ctctttttga ctaaaattaa cgacgcaagc ctaaacgttt gatcaattcg cggtaacgtt
    12661 gaacgtcagt tttacgtaag taagctaaca agttacggcg gtgaccaact tttttcatta
    12721 ggccgcggta tgaatgatgg tcttttttgt gcacgcgtgc atgttcattc aagtggttga
    12781 tttcttcagt taatacagcg atttgtactt ctggagaacc agtatcccct tcatggcgag
    12841 cgtattcgtt gatgatttca ttcttgcgtt cttttgaaat tgccatttct ttcacctctt
    12901 tcgattattc ccctgcgact gagtaaaacg ttggtgattc gcttaaccaa gtggcaggtc
    12961 atgtgcctag agcacacagc tatactttac ctgaaaccgg gttgaaaatc aagtagttaa
    13021 tcattaagaa aaggtagttt tcaaacaatc ttactactac ttttccattt ttgtggtaaa
    13081 ctataatgcg aaaatagact tgaaacacag tcttttaaga aaggggtaca tattccatga
    13141 ttacaatgga tgatatcatt cgtgaaggaa atccgacctt acgcgaagtt gcaaaagaag
    13201 tttctcttcc attaagcgaa gaagatatct ctttaggaaa agagatgctt gagttcttaa
    13261 aaaacagcca agatccaatc aaagctgaag aactacactt acgaggcggt gttggcttag
    13321 ctgctcctca attagatatt tctaaaagaa tcattgctgt tcacgtacca agtcctgacc
    13381 cagaggcaga tggaccttct ctaagtactg ttatgtataa tcctaaaatt ttgagccatt
    13441 ctgttcaaga tgcttgttta ggggaaggtg aaggctgttt atctgttgat cgagaagtac
    13501 caggatatgt tgttcgccat gccaaaatca ctgtgtctta ttatgatatg aatggtgaaa
    13561 aacacaagat tcgtttgaag aattatgaat cgatcgtcgt tcaacatgaa atcgaccata
    13621 tcaacggtgt gatgttctat gaccacatca acgatcaaaa tccatttgca ctaaaagaag
    13681 gcgtattggt gatcgagtag agaattggca ggttccttcg atactatgct acaagaaagc
    13741 tttataaaaa aggggagtgc tcaaaagctg cacttccctt ttttatgttt ctccactaat
    13801 cgaaatttag atagacatct agaaatcgca attccaaaaa attctgtgta ttggatacgc
    13861 atcttttctt attttttctt atttcttcca tatgggtgtt tatctcagag atgatagaat
    13921 agtttctagg ataaaaagta gcagctacga tgttatcctt cgtagaggat tcctgcttca
    13981 gctagttttt gtttgatgtt tttcagcata tgcttttctg ggtagcggat cgtatgcaga
    14041 tggatgccgc ctgttaattc ggataacaaa gtagcattac ttttttgata acgtctcata
    14101 aaggaatcga tatcttgtgg cgttttgatg tgcaaagttc ctgctaactc accgtaaagg
    14161 ggatgttcca caattacatc aatgatttca ccaccatttt caacgattag tctcagttct
    14221 tcttctgttt gatcttttcc atgctggaca gcgattttac tgatgtgccc agtattggtt
    14281 tcttctgttt cgaggatata acctcttgct gttgccacga tacttttacc tgcagctcgt
    14341 agtaaagcaa tatcgcctac aatgatctga cggctgactc caaaagtttt cgcaaacttg
    14401 ctagcactca ctggtttttc tgtatttgcc aaggtttgca tgatttgttt tcgccgtgtc
    14461 tctccttcga tcacacttat tcctccttca ttttgttttg gtattcgcgc gagtgtttca
    14521 tcaaatcaac atacgtgtct gttattgttt ccttatatcc cttatttttc agcagactaa
    14581 caactttatc caatacttgc tgctctcttt ttgcatcata aactgcttgg ttttcttctt
    14641 ttttcacttg tcctatttta gttaccgtat ccattctttt ttctaataaa gcaaccaact
    14701 ctcgatcgat catatcgatc ttatgacgta atgtttcaag agactcttct gttagttctt
    14761 cctctactgt cttgatgata cgagcaggat ttcctgcaat cactacattg tcgggaaaag
    14821 atttggtcac aaccgaacct gcgccgacta ctacgttgtc ccctagagtg acacccggcg
    14881 tgacgataac tcctccgcct aaccaaacat tattaccgat tttaatgggt tttgcgtact
    14941 ccagaccgct gttacgtttc actggatgta gtggatgcgt cgccgtgtaa agctggacat
    15001 tcggagcgaa catgcagtta tcaccgattt caatcgtgct gacatctaaa aatgtacaat
    15061 tgaaatttgc ataaaaattc tccccaacaa atatattata tccgtaatca aaattgataa
    15121 ctggctccat atagattttt ttccctgtac ggccaaaagt ctctttcaac aattgggatc
    15181 gcagttccgc tgattctgct tggttgatga tttggctttg acttcttgca aacatacggt
    15241 cggcaaccag ctcaggatca ttggcaaaat aaagctcgcc tgcaatcatt ttttcttttt
    15301 cggttttgaa ttcagtcata atctgctcct aattcttgta tttttttgaa aacaaccgct
    15361 ccgtcttctt gaataaacgt ataaggctcc gctaaataaa caggcgtttg attgattact
    15421 aagattttgg ctgacggctg gcgaaactgt accagatcac aaaacggatg aacttgaaaa
    15481 ctcgttccaa caatgacgat cagctctgct tggctgacgg cataagccgc ctgctccatg
    15541 actccatctt gaaacccttc accatataac acgatgtctg ggcgtatttg tcctccgcat
    15601 gcttgatgtt tgtcgctgtg aagatattct ttccagtcta ccgtttgttg acattttcga
    15661 caatgacatt gatacagact cccatgaaaa ttgacgagtt gcgggctttt agcctttgcg
    15721 tgcaaaccgt cgatgttttg ggaaacaacc caaacatttt tttctttcgc tagatgtgct
    15781 atttccaaat gaatgatatt gggttttgct tcaggatgat aaatcttttt gacaaattga
    15841 tagaatttat ccggttcatt caccattgct tgatgactca gcaagtattc cggctgctcc
    15901 atcccgtggt agattcctga caaagatcga tagtctggca ctccagaagg tgtggatacc
    15961 cctgcaccgg tcaaaaatgt aatttgctga taagctaata tctcttttgc tgcttcgtct
    16021 actgttaatt gtttcatgtt ttgtcacctc actttccatt atagcccata ctcgaacaaa
    16081 tttattgttg aaaagtcaga aaaatgggaa taaaaaagtg ttatgggcat ttgagcaatt
    16141 tatcacaatg ttcactgaca aaagaatgaa aacgtgttac aatactgctg tataaaagtg
    16201 aggtgaatcg atatgttacc attctttatt tattggggcg ttattctggc ttgtatcgcc
    16261 tggttagcgt taagcgttta tttctctgtt ttttatcttg tacgcaaaga aaatggaaat
    16321 ctttgggctt ttgctttatt caacgtgatt gccgcaattg ttttagccat tacattagcc
    16381 gtatatcgaa catggggctg gggaatcacc caatactcaa gtttgattta tctaatatta
    16441 gccatttatg gcgtcgttgt tcttttgcaa gcgatcctag gacgtgagcc aaagaaagcg
    16501 gcagcttaaa tgatcgagat ggaactggac acaggaaatt ttctgttcta gttctttttt
    16561 tattgtatta catacatttt tgtgtataat tatactatcg tttgcaatgg atagatgatt
    16621 cacattttga ttgttttttc ggtaaaagta aagatttcta tatttatcag tattttttca
    16681 aaaaccagca gttatagatt gacaaagcct ctcgagtatc gtaaactttt tttgtataaa
    16741 taactgaata cgagatgcct caatcaatga ggtagaggtc gcgagaatca ttaaccctgt
    16801 ggagtgaagc aaacatggag aagcaggaat agggaggatc gccgaaatgt gcactttttt
    16861 gcttggagtg tatgttggga cgcaagttaa gagcttgcgg actgtcttag cagtgatgct
    16921 aagttgcgct atgttttgtg agaggtttat caccttatgg aattttagcg gcctttttat
    16981 atctataaat cggtcgcttt ttattttttc agataaagct ttaccgcatt tcatctagac
    17041 cgctcgtgta tcatataatc agaaagggag aaaaaaatga aaaaaaatat ggtttcagtt
    17101 gccgtactat ttgcttttgt cttctcacta ttcagtgtgg gatctctggc aaatgcagat
    17161 gaaaaaacac cgagcgatga gtttcgcgta ggtatggagg ctgggtatgc acccttcaac
    17221 tggtctcaac aaacagatga gaataatgcc ttgccaattc aaggccaaaa tagttacgcc
    17281 ggcggttatg atgttcaaat cgctaaaaaa gtagcagatg gtttagggaa aaaattagtc
    17341 atcgtccaaa cgaaatggga tggtctggct cctgcccttc aatcaggcaa gatcgacgcg
    17401 atcatcgccg gaatgagccc tactgctgaa cgacgaaaag aaattgattt taccgatcct
    17461 tattacgaat cacaattagt agtagtagtt caaaaagata gcaaatatgc aaaagcaaaa
    17521 agtttagcag atctttctgg agcaaagatc actgctcagt taaatacatt ccactatact
    17581 gtgatcgatc agataccaga tgtgcagaaa caacaagcaa tggataattt ctcagcaatg
    17641 agaacagctt tagcttctgg aatgatcgat ggttatgtca gcgaacgtcc ggaaggtgta
    17701 acggcaacta gtgtgaacaa agacttggaa atgcttgaat tcagcggtgc agatggcttc
    17761 cagacaaacc cggaagatgt tcagatttct gttggtatgc gtaaaggcga cccggatatc
    17821 caaaaagtaa accagattct ttctggcatc tctaacgatg aacgaaccaa aattatggac
    17881 caagcagtca aagatcagcc tgctgcaact gatagtgaag aaaaacctgg catcatttct
    17941 gatttcacta cgatttggaa acaatacggc aatatgttct tacgaggtgc tggacttacc
    18001 ttgttcatcg cattgatcgg gacagttgtc ggtactacac ttggattact gattggtgtc
    18061 ttccgttcgg tacctgaatc aggaaatgca ctgactcgct tcttccaaaa aatcggaaat
    18121 gcacttcttt ctatctatgt cgaagtattc cgcggaacac cgatgatggt acaagcaatg
    18181 gtcatcttct acggtctggc actcgctttt ggcatttcat tgaaccgaac gattgccgct
    18241 ttgtttattg tctctctcaa tactggagct tacatgacag agatcgttcg tggggggatt
    18301 tttgcagtag atgaagggca gttcgaagct gcgcaagcca ttggtatgac ccatggccaa
    18361 acgatgagaa aagttgttat tccacaagtt ttacggaata tcttgccagc aacaggaaat
    18421 gagtttgtta tcaatatcaa agatacagca gttttaagtg taatcggcgt agctgatttg
    18481 ttcttccaag gaaactctgc ttccggtgcg aatttccaat tcttccaaac atttacgatc
    18541 gtcgggatca tctacttagt catgaccttt acgatcacca gaatcctgcg ggcggtagaa
    18601 aagaaaatcg atggtccttc agcttatacc aagcttgaag aaatcgacaa ttcaaatttg
    18661 caggaataag gaggaagaat catgaatgaa aaaattattg aaatcaaaca tctaagaaaa
    18721 agcttcggtg aaaatgaagt attgaaagat atcagcgtaa cagtcaataa aggtgaagtt
    18781 gtgacgatca tcggttcttc cggttctggt aaatctactt tcttgcgctg tatcaattta
    18841 ctggaaaaac caacaggcgg cgagatcatt tataatggag aaaatgtatt agctcctaaa
    18901 tataatttac ctaaatatcg aacgaatcta ggtatggttt tccaatcctt caacctgttc
    18961 aacaatatga atgtcttgga aaactgtatg tctggtcaaa caactgtcct gaaacgagat
    19021 aaagaaactg ccaaaaaagt agcaatcgaa aatctggaaa aagttggtat ggatcgttat
    19081 atcgaagcca aaccagcaca attatctggt ggacagaaac agcgtgtcgc aattgctcgg
    19141 gcattatcaa tgaatccaga tgtattgcta ttcgacgaac ctacttcggc gttagaccct
    19201 gaaatggttg gcgaagtgct taatacgatc aaagacttag cacatactgg cttgacaatg
    19261 cttatcgtga cgcatgagat ggaatttgca aaagatgtat ctgaccgtgt catttttatg
    19321 gataaaggtg tgattgcaga agaaggtaca ccagaagata tctttgtcca tccgaaagaa
    19381 gaacgtacaa aagaattcct ttcacgtatt ttaaatgctt aggatcaata gctgattggg
    19441 acaaagagct gcggtgttta ccgcagttct tttttatgaa ttactcataa aaggtaaatt
    19501 tctgaaaatt ttggaatctt agttgtgttt ttcagaaaac tctcttaata tggaagtaat
    19561 taaacttttt tagttaggat gatttaaaaa tgaatgaaga gcaagaactg cagcgtggac
    19621 tgaaaaatag acatgtccaa ctgatttcta ttggcggagc gattggaacg gggttgtttt
    19681 taggttccgg aaagtctatc cagctagctg gcccttcgat attgctcgcc tatcttatta
    19741 ctggatgcat ctgttttttc attatgcgtg cgttaggcga acttctgtta tcaaacacca
    19801 ataaccattc ttttctggat tttgttgcag aatatcttgg caaaaaagcg gctttcatca
    19861 ctggctggac gtattggttc tgctgggtat cgattgcaat ggccgattta acagccatcg
    19921 gaatgtatgt acgctactgg gcgcctggtg ttcctcagtg gcttcctgaa ctgattgcat
    19981 taggtcttct tctttgcttg aatatggtgg ctgtctcatt gtttggtgag ttagagtttt
    20041 ggtttgcatt gatcaaagtt gtagcgatca ttgcctttat cctcgtagga gcttatatga
    20101 tcctcaccca ctatacgaca gatattggca cagccagtat cacgaatcta tggtctcatg
    20161 gcggattctt tccaactggt gcaaaaggat ttatcttagc tttccaaatg gtaacctttg
    20221 cttttgctgg gatagaatta gttggattag tcgctggaga aacagaaaat cctgaaaaag
    20281 tgttgccgga agctatcaat aatattccta tcaggatcat cttattttac ttaggatctc
    20341 tttttgtcat tatggcaatc tatccatgga acagcttgaa tccagataac agtccatttg
    20401 tagaagtatt ttcggaaatt gggatcacga ttgctgcttc cttgatcaat ttagtcgtat
    20461 taagtgcagc agcttctgcc tgcaacagtg caatatatag tacaggacgt atgcttcgtt
    20521 ctttagcgca agaaggcagt gcccctaaaa aattcaaaaa gttaacaaca catcatgtgc
    20581 cagggaatgc tttgacattt tctactatcg tcattttcat ttctgttatc ttgaattacg
    20641 tgatgcctag tgaagtattc acactagtaa gcagtattgc cactacttgt ttcttgttta
    20701 tctggagtat gcttgtctac acgcacatga aatatcgtaa aagtatcctc ggcaaaaaag
    20761 ctcattcatt taaaatgccg ttgtacccat ttagtaatta tctggtattt ctttacatgg
    20821 cctttgtgtg tgtcgtcttg ttcctaggaa aagatacgag aatcgcttta ttactaacac
    20881 ctgtgtggtt cttgcttcta ttactaatct atcatatgaa atatgaacgt aagaagtaag
    20941 aaagtagttg tgacagaagt ggtcagcttc gagaaataag aaggaattta cgaaaattgc
    21001 ttcttaaatt tttgtgaaat ttcggcttat ttcttggaga taaaagcttc tgtcccagcc
    21061 tcttttctat ttccccggaa acaaccgctg ataataggca tctgcttttt tataggaaaa
    21121 aatccaaata ccagatacaa aaaaacgtcc gaataacccg atcaacggta caaaaaagac
    21181 accggcaatc aagcataagt taatcatcat ggagataaga cttcgacggt cctttgacaa
    21241 aactctcacg acatgggaat ctggtttatt tgctttcatg atttgcctca tcaagatacc
    21301 aaaagaaaaa ctccacatcg tgtatactaa gacataagcc atctcaggcc aaaaagcttc
    21361 agggttacgc ccgacccaac tagtaacaga aggacataaa gtcagccaaa agagcaaaaa
    21421 gatattcgac cagaccactc ggtaattaat tcgttctgcc atctgaaata tacgatgatg
    21481 gttcacccag atcaccgcaa caaatataaa gctgatggta taagctaata atgtatttcg
    21541 gatgacccat aaagaatgaa agctagatgt attagggatc ttgatctcta atacaataac
    21601 tctcaaaaca atggctacca ctccatcagt aaatgcttct aatctcgact ttgtcacgat
    21661 gattcctcct cagatgattc agcgctttta ttttatcact tacgttatta aataaccatc
    21721 gttttatata gggaattttc tgaaaattgt tgcatatttt tcgaaatttt gttactttta
    21781 aaaaaaccgt aaaggagtta tgtatgacaa aaaaattatc atttaaagac tatcttttta
    21841 taggctccat gcttttcggt ctattttttg gtgctggaaa tcttatcttt cccgttcatt
    21901 tgggtcaaga agcaggcgct gctacctttt gggcgaatct aggtttcttg gttaccggta
    21961 tcggtcttcc cttcttaggg gtgattgcca ttggtgtatc gaaaagctca ggtgtatatg
    22021 aattagcaaa acggataaat caaacatatg cgatggtttt taccatcttg ctttacttag
    22081 ttatcggacc gttttttgct ttacctcgcc ttgcaaccac atctttcgag attggtttag
    22141 caccatttat cgatcctagc agacagacgc tatatctagc aattttcagt attgtatttt
    22201 ttgtgctggc ttggtggttt tcaagaaaac cgacaaagat attagattat gttggaaagt
    22261 tcctgaatcc tgcatttttg gttttattag gtgctttgct tctccttgct tttttgaatc
    22321 cactaggttc tgtaaatcaa gcgcctattc agccaaatta tcaagagcat gcttttttca
    22381 cagggtttac tcaaggatat aacacattag atgcgcttgc tgctttagca tttgggatca
    22441 tcattgtcac aacaatccaa aacatgggtg taacaaaacc tgctgaaatc gctaaagaca
    22501 cgatcaaatc tggtgcgatc agcattatat tgatgggaat catttatact ttgctcgctt
    22561 atttaggtgc tatgagctta ggtagctttg ctctaagtga aaatggcggg atcacgctgg
    22621 ctcagattgc tgatcattat ttaggtactt atggcagtat cttattagca tttatcgtta
    22681 tattagcttg cttgaagacc ggtattggtt tgattacagc ttttgcagaa acattcacag
    22741 atttgtttcc gcaaagaaat tacgcattct ttgttgcact tgctagtatc cttccttgtt
    22801 tagcggcaaa cgtaggcttg acgaatatca ttcaattttc gttgcctgtt ttgatgttca
    22861 tctatccatt agcaatgaca ctgattttac tagtgttagt tggtcctttg tttaagcagc
    22921 gtacggctgt ttatcgaatg actacttatt ttacattgat tgcttcgatt tttgatgggt
    22981 tgaacgcttg cccagaaact atcaaacaaa cacctattgt tcaaaatctt ttatatgttg
    23041 cggaaagcta cttgccgttt ttcaaattgg ggatggggtg gatcgtacca gcagttatcg
    23101 gttttgttat cggactgatt tggagtttcg ctaagaaaga agaagtagca gattgataaa
    23161 agaggttgtg aaagagacgt tcagccttga gcaataaaaa gtaattttga aaaatggctt
    23221 ctcacatttt tgcataaatt tgacttaata ccgagaaact ggcttttgaa caccgtttat
    23281 tgagcgtcta taaactgacc tgagtattag agaaacaaaa cggcaaagta gctccatata
    23341 ctttgccgtt ttgttttgaa ctaataccga agagaagctg atcaaacaac atttctttta
    23401 taatatagat tttagacata tatatgatat aaaaatagtt ttcgcaaaa
//
LOCUS       DAFEKH010000044        23328 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.045, whole genome shotgun sequence.
ACCESSION   DAFEKH010000044
VERSION     DAFEKH010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23328
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.045"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..209)
                     /locus_tag="LP386_001962"
     CDS             complement(<1..209)
                     /locus_tag="LP386_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBL1919197.1"
                     /translation="MDTITPTNFKENIGKVLQEVVHSNSEIEITRDSKNGLNDGVIMI
                     SKRKWELLQEELYLQRTGTWAYVSD"
     gene            complement(308..622)
                     /locus_tag="LP386_001963"
     CDS             complement(308..622)
                     /locus_tag="LP386_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919198.1"
                     /translation="MAEENKVVPFETLVINKEEFEQLFLDFFIQYDMIYDFSSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSQTFEIDPDYYQPQEVFREFRNKIIGFSQT
                     TK"
     gene            complement(690..1184)
                     /locus_tag="LP386_001964"
     CDS             complement(690..1184)
                     /locus_tag="LP386_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919199.1"
                     /translation="MFKVYFPFQWLVKGILLVLLGLILFGSYLTIKARHFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLINDTENPIRPQQW
                     SIENKDGEELYEYDMILDNPEYIESGKEETVNYYYELPIERQDYQIVVRRENGYIVGL
                     PFTL"
     gene            complement(1177..1491)
                     /locus_tag="LP386_001965"
     CDS             complement(1177..1491)
                     /locus_tag="LP386_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919200.1"
                     /translation="MNYPYFKVSASEETKEIFNNFYNQNKGIFGSKANMFRVMVSNLP
                     VLASPSNNKFNDPESIKFEQKISELESMISNEVIEKLDDIDQKLSYSLKNKYKTEEKK
                     DV"
     gene            complement(1707..3098)
                     /locus_tag="LP386_001966"
     CDS             complement(1707..3098)
                     /locus_tag="LP386_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBL1919201.1"
                     /translation="MGATITSKGRKKNLSSLLQYAANPSKKEKCVAVSGINCSDDSEE
                     ALQEMNLVRTKMNKSKDIAQAFHVIHSFDKSTSKELSIDKMHEIAVEFAEKAFPNSQI
                     IVASHNDKDHFHSHLVINNINMETCKRLRIDPKDLELMRKINDQVLNEHGLESVNNEY
                     YENLEKRTNLYSNDPSKMKYGKINYQEFVQNAIEATLEKCEVNSFEDFSDHLAKEYNI
                     EVYQFSKTNNKLGYVLYKQGVNFYERRGELITLGRDKQSRKEKSQYVERTFSARKLGK
                     RYSFESVSEQLEKNLEESHIKNFFNMEREQVMSLISGVNYKTGELNVPFVELDSIAQK
                     QFSDREGDEKFIKYDDFLREVDKHFVNTMSLEDDQEYTIKLHTDVNPQTLRSAKSKTI
                     SIKKTDQKELFLPAKGFENCSHTPSAKQIHYQISRIMNDDVKMYRAKKDYEFTQQMIE
                     NQQKRQQNFEMEF"
     gene            complement(3083..3694)
                     /gene="mobC"
                     /locus_tag="LP386_001967"
     CDS             complement(3083..3694)
                     /gene="mobC"
                     /locus_tag="LP386_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HBL1919202.1"
                     /translation="MDDKQKMYEKNRKHSEALNFRVDKKTYLELTLIAKQRGISRADV
                     CRERLKGLKYEPPLLAEDDRVVLTKQLNQIGNNLNQAVKALNIIAKYFREESEDKKEK
                     SLHFSFDASRYNIFKDELANSIAKKLMISYPDDIFLESNRSAPSFFKLSEVEKEYFEY
                     WIEKQTRPGTKEEYSQKVDRNLIHSIQIIASLKDEVKQLWELL"
     gene            complement(3698..3895)
                     /locus_tag="LP386_001968"
     CDS             complement(3698..3895)
                     /locus_tag="LP386_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919203.1"
                     /translation="MQLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKNEIESNFKCCSLEKNVRG"
     gene            complement(3886..6564)
                     /locus_tag="LP386_001969"
     CDS             complement(3886..6564)
                     /locus_tag="LP386_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919204.1"
                     /translation="MKIIEKKIANKKINWLVVNFLVLIAMIIFTSNIAHASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSAVNTIVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALI
                     LLMPTMISSGIQFAKTFYKDSTTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNNLTRKNFQQTDLTQVLTDKVIDKLEKENPIADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNSGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGE
                     GEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMRDI
                     ANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSVPTRLSDRKDGAKVEN
                     ADRIMSSSERMREAMKNNAESNNNPASAIQQKVQQDIEERKNAMHGQAKSAEELINQK
                     RHEAKYTPEAMNREEIMLRKRVEGRTGANIDGKEALTKERIQEAKNSNTGLEKLVKEN
                     PQNSTSSHGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNAQGTKTIDVRENLQSS
                     STSQPKTVDVRENVQNSTSSQGFKSVDVRENVQGSSASQPKTVDVRENVQSSTSSQGF
                     KTVDVRENIQKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKSR
                     RRFTYEDNELFRDTLNDPNPLFDNLLRNKRGGLSCN"
     gene            complement(6551..6769)
                     /locus_tag="LP386_001970"
     CDS             complement(6551..6769)
                     /locus_tag="LP386_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919205.1"
                     /translation="MIKNRLIDQVWCLDQNTDSLELIETICFNTIVLDLRAENDNCVT
                     HVIINQKMAQKLSESLRKWAKGGNDENN"
     gene            complement(6845..7897)
                     /locus_tag="LP386_001971"
     CDS             complement(6845..7897)
                     /locus_tag="LP386_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBL1919206.1"
                     /translation="MNEKEVESLVEKQGYSNSDIYAELYYQYPIFLNVNEKYKKMKLS
                     SKLVYMLLKDRNRLSLKNNLYDENQKIFLIFEIKNLVEISGMSKNTILSALDELQKVK
                     LLVKRKNGFNKSKMQMFPNFYYLLKPVLCKDDVYKINKITHQENRQKNLIVQNLNYGT
                     NQYSVDNSKFELCDTSMKTRDKNNFADSSKNELELYKSYKDSKDIKESHNDDLLESLS
                     TKNNKLDEELIETFIEENLLKQIWGESIVNCLKLASNSDYRQFDNWYKKFKYAIRSAE
                     KEQKIQLKIIYEICNNKYFVDHVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASLKNK
                     ALELIELQISEGIDKQ"
     gene            complement(8050..8376)
                     /locus_tag="LP386_001972"
     CDS             complement(8050..8376)
                     /locus_tag="LP386_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919207.1"
                     /translation="MASWLIEEIENERRKIMDAGITVMLDKQQTNQLKNYVFEMTKEA
                     IDQARIDTGLERPFLKGKEMAKYLNVSYTTFLKFKRMGLPVILLEKMELFSKEECKKW
                     ILSHQI"
     gene            complement(8388..8588)
                     /locus_tag="LP386_001973"
     CDS             complement(8388..8588)
                     /locus_tag="LP386_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1919208.1"
                     /translation="MITLNDQFIRSLRRHRADLILTKNDAAKLIGINRKTYVKIENGS
                     KESIRASTYQKLVNWLLNDLKI"
     gene            8711..9313
                     /locus_tag="LP386_001974"
     CDS             8711..9313
                     /locus_tag="LP386_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1919209.1"
                     /translation="MEFTIGGVTLNRIKFYIDSSKKTIKQISTETGINYTTLTNYYRG
                     ERNPRNTETWNILADYFHVPVSYLMGLDETNSIEQPNLDRIKTARLEKKDKIVKNIAS
                     LDSDYFTELSNLYFSMTSLLEVKLQEDDSDFLFLKSILEDSFEYTILFAKQKKFINKA
                     LNLNIDERKELESELFGNLTQVQVNNLKREITARLISKLQ"
     gene            9368..10534
                     /locus_tag="LP386_001975"
     CDS             9368..10534
                     /locus_tag="LP386_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL1919210.1"
                     /translation="MSIQKYTTKSGARYSVRLYVRKDENGKQEYYVKKGFKTEKEAKL
                     HEARKKVEIEDTGYHKPSNDLFITVYEEWLPSYRNRVQETTYQRTKDLFRLHILPKFG
                     NKSISKITPVHCQNAVNEWALKFKNIKQLKSYSSQIFEYAIFAELLHRNPMANTNLPK
                     REKKENENYFSLEELKAFWDILNKEEPLKHILIFQLLITTGIRKGELAALHWSDIYFE
                     EQLMYVRKSYATIRNEEKNARRKTVRIQKNTKNISSERILPIDAQTIEMLKIWKKEQA
                     RELLQFGINTNTKNQLIFTYVNADGDINQPLHADYSNNILKRLEKKYKFKHVTIHGFR
                     HTHATLLLEGGASIKETQDRLGHKNAETTLNTYSHVTEKAQRNALEKFIAYTGL"
     gene            10951..14178
                     /gene="fss3"
                     /locus_tag="LP386_001976"
     CDS             10951..14178
                     /gene="fss3"
                     /locus_tag="LP386_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HBL1919211.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVALVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVNCTVERHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            14291..14605
                     /locus_tag="LP386_001977"
     CDS             14291..14605
                     /locus_tag="LP386_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBL1919212.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            14618..14992
                     /locus_tag="LP386_001978"
     CDS             14618..14992
                     /locus_tag="LP386_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBL1919213.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            15002..15337
                     /locus_tag="LP386_001979"
     CDS             15002..15337
                     /locus_tag="LP386_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HBL1919214.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            15420..16436
                     /locus_tag="LP386_001980"
     CDS             15420..16436
                     /locus_tag="LP386_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBL1919215.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFPDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMGANRFP
                     TSIE"
     gene            17030..18904
                     /gene="ltrA"
                     /locus_tag="LP386_001981"
     CDS             17030..18904
                     /gene="ltrA"
                     /locus_tag="LP386_001981"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBL1919216.1"
                     /translation="MNVETDEVQGSGKNVGKSVMEVPRLNTKIRYWEYYDLQETFDQL
                     FTQSRNGKKFYQLYELIISENNILLAYRTIKANKGSSTPGTDSFTIDNYKEMNQAEFI
                     HLILSHLENYKPKSIKRVMIPKPNGEKRPLGIPCMIDRMIQQMFKQILEPICEAKFYE
                     HSYGFRPLRSAKHALGRIMYLINISKMHYAVDIDIKGFFDNVNHRLLIKQLWNIGICD
                     KQVLAILSKSLKSPIQGEGIPSKGTIQGGIISPLLSNVVLNDLDHWVSKQWHTFETKY
                     PYTKGYNKFRALRDTNLKQGYIVRYADDFKIMTNDYPTALKWFHAVKLYLKDRLKLDI
                     SNEKSKIVNLRKCKSEFLGFAICVKQKGKKWVCNSRISNKKKDQIKEEIKQRIKDIQK
                     SPTAQNALLFNALVLGVHNYFRYATHINLDLNRMNYVLSFTTYNRLSNCSTRCYPNKA
                     SPTYKKFYSTTMKTYKVAGVYLYPLCDVSTKTIYGFNTEDTPFTPFGRQRLEHKSLQS
                     LVFQELRKLMESKIPNRTVEYLDSRISRYSMKSGKCEITKQFLPAKAVHCHHYLPKSL
                     GGDDKFDNLRIIHKDIHLLIHTTNKMIIDHYVHELKLVPEQIAKINLYRKMCNLQNIQ
                     "
     gene            18976..19350
                     /locus_tag="LP386_001982"
                     /pseudo
     CDS             18976..19350
                     /locus_tag="LP386_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346898.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            19445..20120
                     /locus_tag="LP386_001983"
                     /pseudo
     CDS             19445..20120
                     /locus_tag="LP386_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
     gene            20113..20277
                     /locus_tag="LP386_001984"
     CDS             20113..20277
                     /locus_tag="LP386_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919217.1"
                     /translation="MTDKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            20353..21495
                     /gene="dcm"
                     /locus_tag="LP386_001985"
     CDS             20353..21495
                     /gene="dcm"
                     /locus_tag="LP386_001985"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HBL1919218.1"
                     /translation="MRFLDLFAGIGGFRLGMEQASHHCIGFCEIDKFARRSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     AALLRPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYIPQSRERI
                     FLIGHSRDACTEQVFPIIGPSSTSDQNIRNLVNINPSNRGMGGQVYGSDGVAPTLTGD
                     EGIKIALPARDGISVAGLLPGKFEQGNRVYEVTGTAPTLSTKQGGTKIMIRKNETEYQ
                     EVKPGDSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAIVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKEVQKCDL"
     gene            21485..21775
                     /locus_tag="LP386_001986"
     CDS             21485..21775
                     /locus_tag="LP386_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919219.1"
                     /translation="MIYDELVGEIYWVIEKIQSDPELEEQLRRLNFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            22033..23217
                     /locus_tag="LP386_001987"
     CDS             22033..23217
                     /locus_tag="LP386_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBL1919220.1"
                     /translation="MVQQNLDYRLLKDRRNQYGVSQNKLATACGLSRPYLNQIENGGV
                     TTSTKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDVQKIVQEILHLKFDYMLHED
                     YAFYSYQEQYIMGDIVVMLSHEEEKGVLLELKGRGCRQFETFLLAQKRSWYDFFDDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDKSETKNRFEIRLKNDRAYHAIQDLL
                     KGRSIEGTTFSIINRYLRFTDKVEGKRRTNWPLNERWGRFIGRNRKEIQLTSDPKPYT
                     IERTLSWLGRQVAPTWKMAKELDRLNQTTYILDMVQNAQLSDRHKKILEQQSMAIENL
                     II"
     gene            23214..23312
                     /locus_tag="LP386_001988"
     CDS             23214..23312
                     /locus_tag="LP386_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBL1919221.1"
                     /translation="MKRGSSMLGITVMCLIHTSAAADRVMERKVIK"
BASE COUNT         7532 a         4095 c         4217 g         7484 t
ORIGIN      
        1 aaatcagata cataagccca tgtacccgtt cgttgtaaat aaagttcttc ttgtaacaac
       61 tcccattttc tcttagaaat cataatgacg ccatcgttca atccattttt agaatcccta
      121 gtaatttcta tttcagaatt tgaatgaact acttcttgca acactttacc tatattttct
      181 ttgaagtttg ttggagtaat agtatccaaa atgaatacct ctcttctcta tacctctatt
      241 atgaagtgcc cataaaataa agcaagcgtt gaggaataat tctatcaaca cttgctttat
      301 taagctttca ttttgtagtt tgactaaaac caataatctt atttctaaac tctcgaaaaa
      361 cttcttgtgg ttgataatag tctggatcta tttcaaatgt ttgtgagaat aattcattga
      421 atttttctac tgaaataatg attttaccat tcttctctcg actgttttct attatttctg
      481 cttctaattc aaataaatct agtgacgaac taaaatcata aatcatgtca tattgaataa
      541 aaaaatcaag aaaaagttgc tcaaactctt ccttatttat cactaatgtt tcaaacggaa
      601 caactttatt ttcctcagcc attctcccag ttccattttc aaaaatcaca aaactgatat
      661 taccttaaaa actactaaca aaataaaact tataaagtaa atggcaaccc aactatgtaa
      721 ccattctctc tacgtactac gatttggtag tcctgccttt caatcggtaa ttcataatag
      781 taatttactg tttcttcttt gccactttca atatactctg gattatccaa tatcatatca
      841 tactcataaa gttcttcacc atccttattt tcaatcgacc attgttgtgg acgtatcgga
      901 ttttctgtat catttataag tgtataggtc acttgtaata cacgatcatg ttgtgcaaat
      961 tcatttcttt tttcggtcac ttcaatattt ttaaatgtta gttcaacccc atctgcctga
     1021 taagtttcac ctatttttaa atcttttgtt acaattttta ttggcttttc ttctggaaaa
     1081 tgtctggctt taattgttag ataacttcca aaaagaatca atcctagtag cactaaaaga
     1141 attcctttaa cgagccactg aaacgggaag taaactttaa acatcttttt tctcctccgt
     1201 tttgtatttg ttttttagag aatacgataa cttttgatca atgtcatcca gcttttcaat
     1261 tacttcatta cttatcattg attctagttc tgaaattttt tgttcaaatt taatgctttc
     1321 aggatcatta aatttattat ttgatggact agctaacact ggtaaatttg aaaccataac
     1381 acgaaacata tttgcctttg aaccaaaaat tcctttgttt tggttgtaaa aattgttgaa
     1441 tatttcttta gtttcttctg aagccgagac tttaaaatat ggatagttca tttttttctt
     1501 ccacctttct ttttttggga gggagtctgt agggagcttg ctccctcaga gatttacccg
     1561 ccatctgact tgccagaaag tagcctagcg tgagcggggc ggattgactg gcaagtagat
     1621 gggtagctgg cgtatgtcct aaaaactgct tctttccaag caactcttca taggcaaaaa
     1681 actggaaagt ccactaacaa gcccattcag aattccattt caaaattttg ttgccttttt
     1741 tgctgatttt caatcatttg ttgtgtgaat tcataatcct ttttagcacg atacattttt
     1801 acatcgtcat tcattatgcg actgatttga tagtgaatct gtttagcaga aggtgtatga
     1861 gaacaatttt caaaaccctt tgccggtaga aataactctt tctgatcagt ctttttaata
     1921 gaaattgttt tacttttcgc actacgtaaa gtttgaggat tcacatccgt atgaagttta
     1981 atcgtgtatt cttgatcatc ttctaaagac attgtattta caaaatgctt gtctacctct
     2041 cgcaagaagt catcatattt aatgaatttt tcatcgcctt cacggtcgct aaattgcttt
     2101 tgtgcgatgg aatctaattc cacaaacggt acatttaact caccagtttt gtaatttact
     2161 ccactaatta gcgacataac ttgctctctt tccatattaa aaaaattttt tatatgtgat
     2221 tcttctaaat tcttttcaag ttgttcagaa acagattcaa atgaatatct tttccctaac
     2281 tttcttgcac taaaagtacg ttcgacatac tgactttttt cttttctaga ttgtttatct
     2341 cttcctaaag taattaactc acctctacgc tcatagaaat ttacaccttg tttgtaaaga
     2401 acatagccaa gtttgttatt tgtttttgaa aattgataaa cttcaatgtt atattctttt
     2461 gccaaatgat ccgaaaaatc ttcaaaagaa ttcacttcgc atttttccaa cgttgcttcg
     2521 atcgcatttt gcacaaactc ttgataatta atttttccat atttcatctt agaaggatcg
     2581 tttgaataaa gattggttct cttttctaag ttttcatagt actcattatt cactgattca
     2641 agaccatgtt cattgaggac ttgatcgtta atttttcgca ttagttctaa atctttaggg
     2701 tcaatacgca accttttaca tgtttccatg ttaatattat taatgacaag atgactatga
     2761 aaatgatctt tatcattgtg acttgcaaca atgatttgcg aatttggaaa agctttctct
     2821 gcaaattcga cagctatttc gtgcatttta tcaatactta actctttaga agtactctta
     2881 tcaaacgaat gaataacatg aaacgcttgt gctatatctt tagatttatt catcttggta
     2941 cgtactaaat tcatttcttg cagtgcttcc tcactatcat cactacaatt tattcctgag
     3001 actgcaacac atttttcttt ttttgaagga ttagctgcat attgtaatag cgaggataaa
     3061 tttttcttgc gtcctttcga tgttatagta gctcccaaag ttgtttcacc tcatctttta
     3121 aacttgcaat aatctgaatt gagtgaatta aattccgatc aactttttgg gaatactctt
     3181 ctttcgtacc cggtctagtt tgcttttcta tccaatattc gaaatattct ttttctactt
     3241 ctgataattt aaaaaaagag ggggcactcc gattggactc caaaaaaatg tcatctggat
     3301 aactaatcat caactttttt gctatgctat tcgcaagttc atctttaaaa atgttgtaac
     3361 ggctagcatc aaaactaaaa tgtaggctct tttctttttt atcttcagat tcttctctaa
     3421 aatatttagc aatgatattt aatgccttta ccgcttgatt caaattgtta ccaatttgat
     3481 ttaactgttt ggttaaaact accctatcat cttcagctaa caacggcggt tcatatttga
     3541 gtccctttaa ccgctcacgg caaacgtctg ctctagaaat tcccctttgt tttgcaatca
     3601 atgtcagttc aagataagtc tttttatcga cacgaaaatt taaggcctca ctatgtttgc
     3661 gatttttttc gtacattttt tgtttatcat ccattgatta tcccctcaca tttttttcta
     3721 gagagcaaca tttgaaattg ctctctattt catttttcat ctttaattct tcttgaatca
     3781 tcagttcaat ataattagtg accgtgattt tttcatttgt tgcgttcttt actgattcac
     3841 ataattcgtc aagttctaag aaatcatgcg tactaatctt tagaattaat tgcatgacaa
     3901 tccccccctt ttatttctta ataaattatc gaaaagtgga ttaggatcat taagtgtatc
     3961 tctgaataac tcattgtctt cataagtgaa tcttcgtctt gattttgatc ccttatcatt
     4021 ttcacggatt tcactatcaa taatcactgt ttcatgattt gaatcaaatt ttttcgctga
     4081 ctttctgtct tcaacgatat tgattttttg tgttttttct ttcatttctc cactatcttt
     4141 ttgaatgttc tcccgaacat ctactgtttt gaatccttga ctacttgtag aactttgtac
     4201 attttctcgg acatctactg tttttggttg acttgcactg ctaccttgca cattctctcg
     4261 gacatccact gatttaaacc cttgactact tgtagaattt tgtacatttt ctcgaacatc
     4321 tactgttttt ggttgacttg tactgctact ttgcagattt tctcgaacat caattgtctt
     4381 agtaccttga gcatttgaag aactttgtaa attctctctt acatcaacat tccgtccaac
     4441 atgaccattc agtgaacctt gaatattttc tcggacatct actgatcggc caccatgact
     4501 acttgtagaa ttttgtggat tttctttgac taatttttct aatcctgtat ttgaattttt
     4561 agcttcttga attctttctt tggtcaacgc ttcttttccg tcaatattag cgcctgtccg
     4621 cccttctaca cgtttcctta acattatttc ctcgcgattc attgcttcag gcgtgtattt
     4681 cgcttcatga cgcttctgat taattaattc ttcagcagac ttagcttgac cgtgcatagc
     4741 atttttacgt tcttcaatat cttgttggac tttttgctga attgcgcttg caggattatt
     4801 attcgattca gcattatttt tcattgcttc acgcatacgt tcagaactag acataattct
     4861 atcggcattt tcaactttag caccatcttt tctatctgaa agacgtgttg gcacggaatc
     4921 agcatatttt ccagtttcat cttctttatt tttagctaac ataggtttgc tatttttatt
     4981 aatagcggac actgtaccat catctaaacc ttctttaaac ttattcttgg tatcattagc
     5041 tatatcacgc atactcttaa atggttttgt tgctctttca ctagccattg tagctccatc
     5101 tgaagctaaa ccggataatc cacgttcatg ggcatatccc aaagctcttc cagttttgcc
     5161 agcttttttt gatagagttt cgccgaaatt cttttctggt tttcgatctt ctccttctcc
     5221 gcttccttta gcacgattaa atccatttga tccttttcta aacagcattg cgcccattcc
     5281 aaaagcagaa gcaagttgcc catagccttc tttgagtcca atatcaacac caaagtatct
     5341 catgactgtt ccactgcctt tgattaaaac aaaaacggca cagatataag caattgtttt
     5401 tataaaaata tttgttgaga taccttgtcc tgagttcaga aaattgataa acatagcaaa
     5461 cattgataac ccaaatcctt gaaacccaac agttaagtaa cattgtagaa tatctgatag
     5521 aacaactttt gaacgctgtc ctgtctcaat atctgttgca aaaacaagaa cacctaacac
     5581 acgtttaaat gcaagttcta gtattgctgt aatgatcaca aacgcgctga acacataggc
     5641 gattgctaac gctgtcaacc caattgaaat cccccataga tttgcttggt atcggtaata
     5701 gcctgatttc aagctatcag aaaatgttga taagaagttg tcagaaaact ttgtagcaac
     5761 aaattcatta ttagaatttt caactaattc ataacgaaga ttgtccgcaa ttggattttc
     5821 tttttccaat ttatcaatca ctttatccgt taacacttgt gtgagatccg tctgttgaaa
     5881 attttttcgt gttaaattat ttcgatcctc cgttttatca atgcttgagt actgatctgt
     5941 tttattaata tatgctaaat ctgttactcc ttgttttatc aatgaccaag cgactccgtc
     6001 atctgaattt gtaatcgtag tagagtcctt ataaaatgtt ttagcaaatt gaataccact
     6061 agaaatcatg gttggcatta aaagtattaa tgctatagac atcactacgt tcattccaac
     6121 cgattttaaa tccactgttc cttttccagt aatcattttg taaccaacaa acatcaatga
     6181 aaggatcatt aatccaatga caattgtatt tacggctgat tgataaacat tatttagccc
     6241 tgtactttca atgaaattga acaaatccag cacatctgga atcatatttt gaatcgaatc
     6301 tgtcacagta aacatgcctt ttaccacagc ccatccgagc caaatcccga actgactaag
     6361 gaaatctcca ttgtactttt ttaggtaagg tctataaaga gaattattca aaaactctgt
     6421 ttgacttttt gtgtcatcaa accaattgaa aatactcgca tgagcaatat tacttgtaaa
     6481 aataatcata gctatcagaa caagaaaatt aacaaccaac caatttattt ttttattggc
     6541 aatctttttt tcaattattt tcatcgttac ctcccttagc ccattttctg aggctctcag
     6601 agagcttctg agccattttt tgattaatta tgacatgagt tacacaatta tcattttcag
     6661 ctcttaaatc gagaactata gtgttgaagc aaatagtctc gattaattcg agactatctg
     6721 tattttgatc tagacaccaa acttgatcta ttaaacgatt tttaatcaaa ataacccctc
     6781 ctatattcaa agttctcaaa tgaagtggag atacccctcc atttcatttg actcaattct
     6841 attcttattg cttatctatt ccttcgctga tttgcaattc aattagttct aacgctttat
     6901 tttttagaga agcaaagata taatcgtctt tttgtttgat acgatgatct gtttttgctc
     6961 ttcgtatcaa gtcacgtaaa gtcattgata gctgttctct aacatgatct acaaaatact
     7021 tgttattaca aatttcatag ataattttca gttgaatttt ttgttctttt tcagcagatc
     7081 taatcgcata tttgaatttt ttgtaccagt tgtcgaattg acgataatca ctattgctag
     7141 ccagttttaa gcaattcaca atactttctc cccatatttg tttaagaaga ttttcttcaa
     7201 taaatgtttc gatcaattct tcatctaatt tattattttt agttgaaagt gattcaagaa
     7261 gatcatcatt atgtgattct ttaatatctt tactatcttt ataagactta tataattcta
     7321 gttcattttt tgaactatca gcaaaattgt ttttgtctct tgttttcatt gatgtgtcgc
     7381 atagttcaaa ttttgaatta tcaacagaat attgatttgt tccatagttc aaattttgaa
     7441 ctatcaagtt tttttgtcta ttttcttgat gggttatctt attaatttta taaacatcat
     7501 ctttgcacag aacaggcttt aacaaataat aaaaatttgg gaacatttgc attttacttt
     7561 tattgaagcc attttttctt ttcacaagaa gtttaacttt ttgaagttca tctagtgctg
     7621 ataagattgt attttttgac attcccgaaa tttctacgag atttttgatt tcaaatatca
     7681 aaaaaatttt ttgattctca tcatacaagt tatttttcaa tgaaagtcta tttctatctt
     7741 ttagtaacat ataaactaac ttagaactta gtttcatttt cttatatttt tcatttacgt
     7801 ttaaaaaaat aggatattga tagtataatt ctgcatatat atcagaatta gaatagcctt
     7861 gcttttcaac taagctttca acttcttttt cattcattgt cacacctgct tctgatttta
     7921 tttgctataa tagattcaaa taaagttttc tcagaacttt attattgagt gttcccccga
     7981 tctgcaaact gacgggaaca ctctttttaa ttttttctac ttcatcaaat ttaaaaaacg
     8041 aggtgttttt taaatttgat gactcaatat ccattttttg cattcttctt ttgaaaacaa
     8101 ctccattttt tctaataaaa taactggcaa tcccattctt ttaaatttca aaaaagttgt
     8161 atatgataca ttcaaatatt tagccatctc ttttcctttt agaaatggtc tttctaatcc
     8221 ggtatcaatt cttgcttgat caatagcctc ttttgtcatt tcaaaaacat aatttttcaa
     8281 ttgattcgtt tgttgtttat ctaacattac tgtaattcct gcatccatta tttttctcct
     8341 ctcattttct atttcttcaa tcagccaact cgccaagttg tatttattta gattttcaaa
     8401 tcattaagta accaatttac caacttttga taagtagatg ctctaatact ttctttgctc
     8461 ccattttcga ttttgacata tgttttccga tttataccta tcaattttgc tgcatcgttt
     8521 ttagtaagta taagatcggc tctatgtctt cttaagcttc taatgaattg atcattaaga
     8581 gttatcattc agcgcctcct ttcaaattat tcactttgtg gtttttatct taataagcac
     8641 attttaaacc acaaaacgag taatatcaat taaaatatta ctcaatttgt ggttttcatg
     8701 ctataatagt ttggaattta ctataggggg cgttactttg aatagaataa aattttatat
     8761 tgattccagt aaaaagacca ttaaacaaat tagtacagaa actggtatta actatacaac
     8821 tcttacgaac tattaccgtg gtgagcgaaa tcctagaaat actgaaacat ggaatatcct
     8881 tgctgattat ttccatgttc ctgtaagtta tttgatggga ttagacgaaa caaattccat
     8941 agaacaacct aatcttgata gaataaaaac tgctcgttta gaaaaaaagg acaaaatagt
     9001 caagaatatt gccagtcttg actcagatta ttttactgaa ttatctaatc tatacttttc
     9061 catgacttct ttacttgaag tcaaacttca agaagatgac tccgactttc tttttttaaa
     9121 aagtattcta gaggactcct ttgaatacac gattctattt gccaaacaaa agaagtttat
     9181 taataaagct ttaaacttaa atatcgatga aagaaaagag ttagaatctg agttatttgg
     9241 caacttaacc caagtacagg ttaacaatct aaaaagagag ataacagctc gattaatatc
     9301 aaaacttcaa taaaactaat tattcaatca gccaactcgc caagttatca gattggagag
     9361 attagttatg tcaatacaaa agtacacaac aaaaagcggt gcacgatata gtgtccgctt
     9421 gtatgttcgt aaagatgaaa atggaaagca agaatactat gtaaaaaaag ggtttaaaac
     9481 tgaaaaagaa gccaagttac acgaagcaag aaaaaaggtc gagattgaag ataccggcta
     9541 tcataagcct tctaatgact tgtttataac agtgtatgaa gaatggttgc cttcttatag
     9601 gaatcgtgta caagaaacga catatcaacg tacaaaagac cttttccgct tgcatatact
     9661 accaaaattc gggaataagt ccatttctaa gattactcct gttcactgtc agaatgcagt
     9721 caatgaatgg gctttaaaat tcaagaatat caaacagctt aagtcttaca gctctcaaat
     9781 atttgagtat gccatttttg cagagctatt acaccgaaat cctatggcaa atacaaatct
     9841 accaaagcgg gaaaagaaag aaaatgaaaa ttacttttca ttagaagaac taaaagcttt
     9901 ttgggatatt ctcaataaag aagagccttt aaaacatatt ttaatcttcc agcttttgat
     9961 tactactggt atacgtaaag gagagctagc tgctcttcat tggtctgaca tttattttga
    10021 agaacagcta atgtatgtta gaaagagcta tgcaactatt cgaaatgaag agaagaatgc
    10081 aagaagaaaa actgtcagga ttcaaaaaaa tacaaaaaat atatcttccg aacgaatatt
    10141 accaattgat gcacaaacta ttgaaatgtt aaaaatctgg aaaaaagaac aagctcgaga
    10201 gcttttgcag tttggcataa atacaaatac aaaaaatcaa cttatcttta cctatgtaaa
    10261 tgcagacggt gacattaatc aacctttgca tgcggactat tcaaataata tattgaaacg
    10321 tttagagaag aaatataaat ttaagcacgt tactattcat ggattccggc acactcacgc
    10381 tactcttcta ctagaaggtg gagcaagtat caaagaaaca caagatcgat tgggtcataa
    10441 aaatgctgaa actaccctta acacttattc tcatgttact gaaaaagctc aacgaaatgc
    10501 gttagaaaaa ttcattgctt acactggttt ataatattgt cattaccttt ctcattacca
    10561 gaacgaaaaa aagacacctt ctcgcaatga gaaagtgtct gaaatcgttg gtataacaac
    10621 gattaacgtt ttgaaaactg tgaagcttta cgtgctttct taagacctgg ttttttcttc
    10681 gtatcattga ataagtttga aaaaccttga tttataaagg ttttcccgta aatatatttt
    10741 attatatttg attaaatttg aaatgtttgt gttctaaaat gtgttctaat ttaaaggcag
    10801 tatatttcgt attttagatt aaatttttag gctcattcat tctcaaatcc attctattca
    10861 gtcaataaaa attttaaaaa gactttataa acaaagatgt tcaagcgagc atcttatttt
    10921 tttgtgctta atttgaaagg agaacatttc atgtataaaa aacaaaaaaa gaaattatgt
    10981 gtattaacta ttttgagttt ggctgttcaa gcaattgttg gagcaattgc tcctacgatt
    11041 acttttgctg atgaaattac ccatccacaa acggtaaccg tagaactaga tttagcacat
    11101 caatatgctg ttgaaggaac ttttagtgat ggtcgtccaa tgtcagaagt cactgttccg
    11161 cattatgcag tgtacaacgg ctttaaacaa gatattttct gtattgaacc aggagtcccg
    11221 atttacaatg agttcactcc tggctatgag aaaaacccgt taccagatat gtccgataaa
    11281 gccaaattag tttccgtttt atggaaaaaa gtaggtacag atgcagatac tcatattgtg
    11341 gcacagaaga tgatctggca agaagttaat gggtataccc ttcactcaat aaaacgatca
    11401 gatggtagtg ccgtaaatat cgcagccatt gaggcaaaaa taaatcaagc cattgacgat
    11461 tatcagaaga aaccaacctt ccataatagt acggctaaaa cagtattagg gcaatcgact
    11521 actgtgacgg atacgaataa tctgaatttg tcagagttcg atgaggttgt ggaaaatgcc
    11581 gcaaacattg attatcgtgt gaatggtaat cagttgataa tcaccccaaa tgccaattca
    11641 aaagaaagtg gtgtgctgac gcttaagaaa tctgctggta ccggaacacc tgtcgcctat
    11701 aaaaaggctg gccaacagac tttaatggcc ggggcgattg ataaacctaa tacctacaca
    11761 atcaaaattg atgtggaaac ggagggttct ttaaagatca aaaaagtcga taaagaatcg
    11821 ggtgatgttg taccaggaac ggttttccat ttagactttg gaaaaacttt acctgcaaaa
    11881 gacgtgacta ctgacaaaga aggcattgct acattggatg agattcctca tggtacaaaa
    11941 gtaaccatta ccgaaaaatc agtaccggcg ccttatacga ttgataccac ccccatgact
    12001 accaccatta aagcaggcga aaccatttac gtgacttcaa aaaacgcacg ggaaaaaggg
    12061 caaatcattc tggataaaag cggagttgaa acagggagtg atctttggaa tgacaattat
    12121 tccttagctg gtaatacgtt tgccattcgc aaagacagtc caaccggtga aatcgttcaa
    12181 gaaatgacca cggatgaaaa cggtcatgcg gaaacaccaa aagagattgc taatgcgttg
    12241 gaattgggaa cctattatgt gaccgaaact aaagctagtc atgggttcgt gaatacgttc
    12301 aaacctgtaa aagtcgaatt gaagtatgcc aatcaaaccg tagcccttgt taccagtaac
    12361 gtaaaagggc aaaatcaaga agtcactggc gaaaccactt tgacgaaaga agacaaagat
    12421 actggggata aagcacaagg taaggcagtc tttgagggtg ctgaatacac cttgtttact
    12481 gctaaggatg gaaaagctgt taaatggagt gaggctttta aaccagagtt agcgaaggga
    12541 acgaaaggtt ctgatgaaac ggtcactttg actttagacg aaaagaacca agttgccgtt
    12601 aaacatttag ctatcaacga gtattattgg caagaaacaa aagcgcccga aggatatagc
    12661 cttgatgaaa caaagtatcc tgtatccatc aaaaaggtgg atgatagcga aaaaaatgcc
    12721 gtgattaccc gaaatgttac ggcaaaagaa caagtgattc gctttggctt tgatttcttt
    12781 aaatttgctg gatcagctgc gggcactacc gaaactggct tcaatgatct gacctttaaa
    12841 gtgtcgccat tggaagggac caatgaaatc acaggtgccg aagatgaagc gaccacagct
    12901 tataacgagc aattagggtt tgatggttat ggcaagtttg aaaatcttcc ttatggggat
    12961 tatttacttg aagaagtaga agccccagaa ggttttcaaa agattacgcc attagaaatc
    13021 cgttctactt ttaaggaaaa caaagaagac tttgtgaaga gtgagtatgt ctttaccatt
    13081 accgaacaag accaaaaaca accaattaaa acggtgaccg ttccttacga gaagctgacg
    13141 aacaaagcat tttctgttag tttgaaccgt ttaatgctct atgatttgcc tgaggaagaa
    13201 gatagtttaa cttctcttgc gacttggaaa gacggaaaca aagaattaac ttctctggat
    13261 tctaccgagc tagttgataa attgagttac aatctacatg aaatcaaaga agactggtat
    13321 gtggtagcgc aagccattga tgtggatgcg acaaaagctg cccaagaaaa agatgaaaaa
    13381 gccaaaccag tggtgattgc agaaacaagc gcaacgttgg cgaacaaaga gaaaacagga
    13441 acttggaaaa ttcagcataa attaaccgcc gaacaagttt taaataaaac tattgtctta
    13501 ttcaactatg tgtatgaaaa taaggaagct tttgaagcag gcgataagcc agtagcgaag
    13561 gatgttagct tgaataatca agcccaaact gttaattgta cggtggaacg tcatgtttct
    13621 atccaaacaa aggcccacct agaaaacggt tctcagacct ttactcatgg tgatgtggtg
    13681 gatatgtttg atgatgtgtc gattactcat gatgtactgg atggctcaaa agaagctttc
    13741 gaaacaattc tgtatgcttt attaccggat ggtacaaaca aagaaatttg gaaatctggc
    13801 aagattgatt atgaagtaaa tgataaagaa ttcaccaaaa ctgtgcttgc gaaaaaagta
    13861 gataccggaa aatatccaga aggaaccaag tttacttttg cggaaatcaa ttacgataaa
    13921 gatgggaata tcaatggaaa acacaatgaa gatttgaaag aaaaatctca aaccttaaca
    13981 ccaaaagaag ttccaaccat actaagtacg ccgaaacaac cggaaacacc aactgttcca
    14041 agtggctctc aagaatctag tcccacagtg aagaccttcc ctcaaaccgg ggagaaaaat
    14101 tccaatgttt tactgttcat tggttttact ttgatttttg cgacggcggg ctattatttc
    14161 tggaatcgcc ggaactaagg tgatgagatg atacaagtaa atcctaagaa ccaacgtgcg
    14221 cgaccgcctc ctaaaaaagt agtcgcgcta tttttgtatc caaaactaac aatgaaaaga
    14281 ggaaaagaag atggaattga aatttgtcgt gccagatatg gctgaaacct ttggaaagtt
    14341 aagttatgcc ggtgaaggag aaattataac agaaggatat ggacggaata ctacggtgat
    14401 tggtcgcagt tatcatttgt attccagtaa gcaacgggcc gatgatattg aggtggtagt
    14461 agctgcggaa gccggtgaaa aggattttga tcaagaccaa ccgctaaaag ccgtgaatcc
    14521 ccatttggtt gccaaaggct atgagattga gaatcgtggg tttactgatt acgtgttgta
    14581 tgttgatgat ttagtgaaag cataggagga aaagaagatg agattaacag aaggtattgt
    14641 cgtagattca ggtttaacat ttgggaagtt gcgtttttcc gcattacgcc gagaagtacg
    14701 gaagcaaaat gaggatggaa caattggtaa tgaggtaaaa gaacgaacct ataatttaaa
    14761 atcctctgca caagggcgaa tgattcaagt tagtatccca gctaatgtac ccttacgcga
    14821 gtttgcttat gatgcagagg tagagttggt caatccaatc gtggataccg ttgccaatta
    14881 tgtttttcga gaaggaacta ccgttaattg gttcattaag gcggatgatt tagtcttgaa
    14941 gcggcagccg aatcaaggaa atcctacgaa ccaaaatgaa agaaagaaat aggtgaagat
    15001 tatggaaatt aatgttgaac atattttaga ttgtctcgat caatatggaa aaggcgagct
    15061 gactgaggaa caactcgtta aagcattaac ctctgatgaa aaaatgtttc tgattataca
    15121 tcaaggttta cttggagaaa atagcgacag tgaagaagac tctgatgtac tagactggtt
    15181 aggagaagaa gagtctttct ttatagttgt cgaagtaaat gaaaacttat gtcggcaggc
    15241 agaatccatt ttggaagaaa ttggtgtgga gatgccggat gctattgaag gctttttaaa
    15301 tcaattggtt gaaacgaaac aactcccctc ctcgtagcag taaatgacta gcataacttt
    15361 ttgaaattgc ctaatgaaat cctattgggc tttttcgatt ggaggtggaa accatcaaaa
    15421 tgtacaaagg acatcgcata cgcgcaggag atcagcactt ggtttatcac tttgttcttg
    15481 gctggctact cgctctgttc atcggttgga tgagcgtctt ttattttcaa gagtttagac
    15541 aatttgatat ttctaagcta tcactttcta ctattgaaat cgtttggtct ataaaagatt
    15601 tagtatgtct gcttggaagt ctcgcttttt caggagctat gatattgctt tatattcact
    15661 tttttcctga tcattggcga agcttgtggc atcgacaaaa gctagctcgg atgattctag
    15721 agaaccattg gtatgaagtg aaacaaactc aaagtgaagg ctttttcaaa gatttgaata
    15781 gtagccgaac cagagagact atcagttact tccccaaaat ctattatcga atgaaagatg
    15841 gattactgtc tattcgcgtt caaatttcac ttgggaaata ccaagatcag cttttaaaat
    15901 tggaaaagaa gttagaaagc ggactgtatt gtgagttagt agaaaaggaa ctcaaagact
    15961 cctatgtgga gtatacttta ctgtatgata tgatcgccaa tcgaattggg atagacgaag
    16021 tagtggcaga aaatgggact ctgcgattga tgaaaaatca agtatgggct tatgattctt
    16081 taccccatat gttaatcgct ggtggcacag gtggagggaa gacctatttc ctcctcacca
    16141 ttatcgaagc actattgaag tcagatgcag aattgtttat cctcgatccc aaaaatgcag
    16201 atttagctga tttaggtacg gtgatgcctc atgtttattc acaaaaggaa gaaatttctg
    16261 cttgtgtgga agatttctat gaacgtatga tggctcgtag caaggcaatg aaagaaatgt
    16321 ctaactacaa aacaggagag aattatgcct atcttggact tccacccaac tttttaatct
    16381 ttgatgaata cgtggcttat atgggtgcga atcgttttcc tacaagcatc gaatagatgt
    16441 gaaatggaag cctattgaga ttatcaatag tgacaactaa tgttttgaga gatggaatga
    16501 aagccttcaa gttgagctga aacatccccg ctaatactcc tacatgctct aatcaatgaa
    16561 gtagattggt tttggtatga agctaggtga agtcgtctga aatctgccta agtgcttgag
    16621 cataaggctg actatagggc gggcggctga aaaagataac tatggtaaga atgtctgaaa
    16681 atgactgacg aatctgcgaa tgtacgggtc taaaaggctg atcttattga aagataggaa
    16741 catacggacg tatggtgaga taccgacaag taaggttcca tgatatgaaa atcgggatag
    16801 ctaacgaaga agctataatt tcacaggctc atagtagata cctaaggtta tacatgatag
    16861 ctaaaaacat tggaacgatg taagcagaaa actatcaatt aaatgactac ttctagatag
    16921 gtgcatataa gtaataacga aattgctttg tttctgtgaa agtaagggca cagtaccgat
    16981 gaagcgtcta acaaatgtgg agggatagcc ctaagtctat ttaataacaa tgaatgttga
    17041 aacagatgaa gttcaaggat ctggtaagaa cgtgggaaaa tccgttatgg aggtgccacg
    17101 cttgaacaca aaaatacgtt actgggaata ttatgatcta caagaaacat tcgatcagct
    17161 atttactcaa agtagaaacg ggaaaaagtt ttatcaatta tatgagttaa tcatttctga
    17221 aaataatatt cttttagcat accgtactat caaggcaaac aaggggtctt cgacaccagg
    17281 aacggattcc ttcacaattg ataactataa ggaaatgaac caagcagagt ttatccatct
    17341 tattctcagt catttagaaa attacaaacc aaaatccata aagcgagtaa tgatacctaa
    17401 acccaatggt gagaaacgcc cattaggaat tccatgcatg attgatcgaa tgatccaaca
    17461 gatgttcaag cagatactgg agccaatatg tgaagctaag ttttatgaac atagctacgg
    17521 tttcagacca ttgagaagtg caaagcatgc tctaggtcgc attatgtatc tcataaacat
    17581 cagtaaaatg cactatgcag tagacattga tatcaaaggt ttctttgata atgtaaacca
    17641 ccgtttactg ataaaacaat tatggaatat aggaatttgt gacaaacaag tcttagctat
    17701 tctttcaaaa tctctgaaat cacccattca aggagaaggt atcccgagca aaggaacgat
    17761 ccaaggaggt atcatttctc cactattatc taatgttgtt ctaaacgact tagaccattg
    17821 ggtctcaaag cagtggcata cctttgaaac aaagtatccc tatactaaag gttacaataa
    17881 atttcgtgct ctaagagata caaatctaaa gcaaggctat attgtcaggt acgcagatga
    17941 ctttaaaatc atgactaatg attatccgac agcattaaaa tggttccacg ctgtcaagct
    18001 ttacctaaaa gacagactta aattagatat ttccaatgag aagtctaaaa tcgtcaattt
    18061 gcgtaaatgt aagtcggaat ttttaggatt cgctatttgc gtgaaacaaa aagggaaaaa
    18121 atgggtttgt aattcacgta tttctaacaa aaaaaaggat cagattaaag aagagattaa
    18181 acaaagaatc aaagatattc aaaagagtcc tacagcacaa aatgctctcc tgtttaatgc
    18241 tctcgtgctc ggtgttcata attatttcag gtatgccact catattaatt tagatttgaa
    18301 taggatgaac tacgttcttt cattcactac ttacaaccga ttatcaaatt gtagtacaag
    18361 atgttacccc aacaaagctt ccccaactta caaaaagttt tactcaacaa cgatgaaaac
    18421 gtataaagta gctggagtct atttgtaccc tctttgcgac gtatctacaa aaacaattta
    18481 cggatttaat acggaggata caccgtttac tccgtttggt cgtcaaagat tggagcacaa
    18541 aagcctacag tctcttgtgt tccaagaatt aagaaaattg atggaatcga aaataccgaa
    18601 tagaacggtt gagtatttag atagtagaat atctcgttac tcaatgaaat caggcaagtg
    18661 tgagattaca aaacaatttt tgccagcaaa agccgttcac tgtcatcact atttgccaaa
    18721 aagtcttggt ggagacgaca aattcgataa cttgagaatt attcataagg atatccatct
    18781 tctgatccat acaacaaata aaatgataat cgatcactac gtgcatgaac tgaaactggt
    18841 gccagagcaa atagcaaaaa tcaaccttta tcgaaagatg tgtaatctgc aaaacattca
    18901 atagaaaata aatagatgga acgccgtatg aggtgaaagt ctcacgtacg gtgtggagcg
    18961 ggggaaaaga tggagattat atcaaattct tacctatcgc tatagatgtt aacgacgaaa
    19021 gaaagtgcgg tgattttgaa taagctcaaa caaatcgtga tgttgggtcg tcaatctggt
    19081 ttctttctga ttttggcttg ccaaaggccg gatgcgaaat atttaggaga cggaatccgc
    19141 gatcaattca actttcgcgt ggctttgggt cgtatgagtg aactcggata ttccatgatg
    19201 tttggggagg tcgaaaaaaa cttctttatg aagcacatca aaggtcgagg ttatgtggat
    19261 acaggtggca gtgtgattag tgagttttat acgccacttg taccaaaagg gtatgatttc
    19321 ttagattcaa ttagtaaatt agtaaattag aaaagatgaa tgattgagtg atcttcaata
    19381 ctgactttat acttcaagta acgtataata cttttatata gtaggaagaa aggggataat
    19441 taatatggaa agtaatgatt cttatttaga gtatgcaaaa gcaaataagg ataagtttat
    19501 ttcttatatt atcaaaggga aatcccccga agttggacga gacgcagttt ttatggcagg
    19561 gagtcctgga gctggaaaat cagaggttgc cattggatta gctgagaatt atgataacca
    19621 tgtgattatt gatgcggatt actttcgcac ccagtttcct gattataatg gaaaaaaact
    19681 ctagtctctt tcaaaaagca tcttcttggt tggtagagca ggcatttaga tatgtcttag
    19741 atcatggcta ttcttttatt ctggatgcaa cttttgcaat attaagtgct gaaaaaaata
    19801 tctcgcgggc gttgaaaaaa cattttcgag tgacgatttt ctacgtttat caagacccta
    19861 aaatcgcttg gaaatttaca caagaacgtg aaattgcaga gggacgtcat gtgccgaaaa
    19921 aggtatttat taacgctttt ttcaaatcaa gagagaacat tgcaaaagta aagagtaaac
    19981 atccagatgt attgcttcat atcataataa aagattatac gaataatatt tccgaagttc
    20041 attatgctgc ggacaatcta gaattatttt taccactagg gtatagtagg aaagatttgg
    20101 aggttcaatt acatgactga taaagaacaa gtaacgaaaa ttgtaaagaa atacaataag
    20161 agcattgcgg atttatcgga aaatgctact gcaaaagagt tcaaaacggt gattaaatat
    20221 gtagccgatc aggccaatga aaaacaacgg aaattagttg gattaaataa aaaatagtag
    20281 gacaaattaa taatgtatga gccaagagca aaatgttctt ggcttttttc tttgcaatga
    20341 atgaggtaat gtatgagatt tttagattta ttcgccggta ttggtggctt tcgtttaggt
    20401 atggaacagg cgagccatca ttgtatcggt ttttgtgaaa ttgataaatt tgctagacgt
    20461 agttataaag caattcatga tacaagtaag gaggtggaaa tgcatgacat cacaagtgta
    20521 tcagatgagt ttattcaatc cctcggacca gttgacatcc tttgcggcgg atttccgtgt
    20581 caagcttttt caattgcggg aaagcgacaa ggattttccg atactcgagg tactttattc
    20641 tttgaaatcg ctcggttcgc cgctcttctc cgacctaagt ttttattcct tgagaacgtc
    20701 cggggattgc tcaatcacga agggggggct acgttcgaga cgatcctccg aacgctggat
    20761 ggattggggt atgacgtgga gtggcaggtg cttaactcaa aggcctacat tccccaaagc
    20821 cgggagcgta tcttccttat cggacattct cgagacgcat gtaccgaaca agtatttcct
    20881 atcattggac cgtcttcaac atctgatcaa aacatcagaa atttggtaaa tatcaatcct
    20941 tccaatcgag gaatgggtgg acaagtctat ggttcagatg gcgtagcgcc aaccttaaca
    21001 ggtgatgaag gaatcaaaat tgcactgcca gcaagggatg gaatctctgt agcaggacta
    21061 ttaccgggaa agtttgaaca aggtaatcga gtttatgaag ttactggaac cgcccccacc
    21121 ttgtccacga aacaaggtgg tacaaaaatc atgattcgaa aaaatgaaac agaatatcaa
    21181 gaggtgaagc caggagacag tgtgaacctg gcttttccta attccacaag tcgccgaggt
    21241 cgtctgggaa aacagagtgt tcatacttta ctgacaggag accaacaagc gattgtcacg
    21301 gatcagtatc aaattcggaa gctaacacct agagagtgtt ggcgacttca gggctttccc
    21361 gattgggctt ttgatcgagc ttctcaagtc aattcagata gtcagttgta taagcaagcc
    21421 ggaaactctg taacagttcc ggtcattttt gatattgcca gaagattaaa ggaggtacaa
    21481 aagtgtgatt tatgatgagt tggttggaga aatttattgg gtgattgaaa agattcagtc
    21541 agacccagaa ttagaagaac aattgcgacg gttaaacttt gatattcgca agaatggtgt
    21601 caaagtcgct ggcgatccat atttaatgaa tgaggagacg gatgctcgaa ttgaaataaa
    21661 ccaagtaatt gcagaatttg agcggattgc ggaccaagca aaagaaccgg atattcgtca
    21721 atacttgtta gaaatgaaag cagagttgga agtaaatggt attacagatg agtaacctaa
    21781 accaacacaa ctgactgtta ggcgctgacc gcggaggatt cgcgaagcag aaatcctccg
    21841 tggtgctgtg cctgttcatg gacggcgtta gccggccatg atgtctcacc ccccgtatct
    21901 aacagggggg tacaaaaaca caaaaaacaa gcaagcagcg attaagaatg gttgtcatga
    21961 cgaggatagt tagctgtttg aacaggtgtt aactcatttt gaaaagttaa caccttattt
    22021 ggaggtgaaa acttggtaca acagaactta gattatcgtt tactaaaaga tcggcgcaat
    22081 caatatggtg tttctcaaaa taaattggct actgcttgtg gattgagtcg tccctatttg
    22141 aatcaaatcg aaaatggtgg cgtaactaca tctacaaaaa ctatgagaaa aatttttgac
    22201 caactggaaa gtttcaatcc cgatttgcct ttgacgttac tgtttgatta tgtaaggatt
    22261 cgttttccga caacggatgt tcaaaaaatt gttcaagaga ttttgcattt gaaatttgac
    22321 tatatgcttc atgaagacta tgccttttat tcgtaccaag aacaatacat catgggtgat
    22381 attgtggtga tgctttctca tgaggaagag aaaggcgttc ttttagaatt aaaaggtcgt
    22441 ggttgtcggc agtttgaaac ttttttgctc gctcaaaagc gtagctggta cgactttttc
    22501 gatgattgct taaaagctgg aggcgtcatg aaacgcttgg atttggcaat caatgatcga
    22561 gttggcttat tggatattcc tgagttgacg aaaaaatgtc agaaggaaga atgtatctcc
    22621 ttattccgga cttttaagag ttaccgctcg ggtgaacttt tgaaagctga tgaaaaggat
    22681 ggaatgggaa atactttgta tatcggaagc cttaagagtg aggtttattt ttgtttatac
    22741 gaaaaagact atgaacaata tatcaaattg ggaattccgt tagacaagag cgaaacgaag
    22801 aatcgctttg aaattcgatt gaaaaatgac cgtgcctacc atgcaataca agacttgtta
    22861 aaaggtcgaa gtattgaggg taccacattt tccattatca accgttactt acggttcacg
    22921 gataaagttg aagggaaacg gcgaacaaac tggccgctaa atgaacgatg gggtcgcttt
    22981 atcgggcgaa atcgcaagga aattcaactg acttctgacc ccaaacctta tactatcgag
    23041 cgaacactga gctggctagg tcgacaggta gcacctacgt ggaagatggc taaggagtta
    23101 gatcggttaa atcagacgac ttatattctt gatatggtac agaatgctca gctatcggat
    23161 cggcataaaa agattttgga acaacaaagt atggcaatag aaaacttgat tatatgaaaa
    23221 gaggaagcag tatgcttggt attaccgtga tgtgcttaat tcatacaagt gcggctgcag
    23281 atcgagtaat ggaaaggaaa gtgataaaat gaatttcgga caaaattt
//
LOCUS       DAFEKH010000045        23099 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.046, whole genome shotgun sequence.
ACCESSION   DAFEKH010000045
VERSION     DAFEKH010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23099
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.046"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            103..273
                     /locus_tag="LP386_001989"
     CDS             103..273
                     /locus_tag="LP386_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919222.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
     gene            493..1200
                     /locus_tag="LP386_001990"
     CDS             493..1200
                     /locus_tag="LP386_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL1919223.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(1259..1903)
                     /locus_tag="LP386_001991"
     CDS             complement(1259..1903)
                     /locus_tag="LP386_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HBL1919224.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGSVSYHEQLITDHI"
     gene            2030..2317
                     /locus_tag="LP386_001992"
     CDS             2030..2317
                     /locus_tag="LP386_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919225.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            2425..2745
                     /locus_tag="LP386_001993"
     CDS             2425..2745
                     /locus_tag="LP386_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1919226.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            2826..4139
                     /locus_tag="LP386_001994"
     CDS             2826..4139
                     /locus_tag="LP386_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBL1919227.1"
                     /translation="MNHFWGRRLLTRDIEAIDCEEVNLPNYEKIAAVERLGNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEISKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKML"
     gene            4136..4855
                     /locus_tag="LP386_001995"
     CDS             4136..4855
                     /locus_tag="LP386_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HBL1919228.1"
                     /translation="MRCSCCSKDIFQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVKSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQVAQPKIIRTISLAR"
     gene            4983..5534
                     /gene="raiA"
                     /locus_tag="LP386_001996"
     CDS             4983..5534
                     /gene="raiA"
                     /locus_tag="LP386_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBL1919229.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            5756..8290
                     /gene="secA"
                     /locus_tag="LP386_001997"
     CDS             5756..8290
                     /gene="secA"
                     /locus_tag="LP386_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBL1919230.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTSQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            8416..9517
                     /gene="prfB"
                     /locus_tag="LP386_001998"
     CDS             join(8416..8487,8489..9517)
                     /gene="prfB"
                     /locus_tag="LP386_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HBL1919231.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            9622..10308
                     /gene="ftsE"
                     /locus_tag="LP386_001999"
     CDS             9622..10308
                     /gene="ftsE"
                     /locus_tag="LP386_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HBL1919232.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            10292..11185
                     /locus_tag="LP386_002000"
     CDS             10292..11185
                     /locus_tag="LP386_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1919233.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIRPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            11337..12785
                     /gene="cls"
                     /locus_tag="LP386_002001"
     CDS             11337..12785
                     /gene="cls"
                     /locus_tag="LP386_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBL1919234.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHTTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            13122..13979
                     /locus_tag="LP386_002002"
     CDS             13122..13979
                     /locus_tag="LP386_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HBL1919235.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            14094..15014
                     /gene="pstC"
                     /locus_tag="LP386_002003"
     CDS             14094..15014
                     /gene="pstC"
                     /locus_tag="LP386_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HBL1919236.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            15014..15898
                     /gene="pstA"
                     /locus_tag="LP386_002004"
     CDS             15014..15898
                     /gene="pstA"
                     /locus_tag="LP386_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HBL1919237.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVMKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            15913..16719
                     /gene="pstB"
                     /locus_tag="LP386_002005"
     CDS             15913..16719
                     /gene="pstB"
                     /locus_tag="LP386_002005"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBL1919238.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDIHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            16735..17493
                     /locus_tag="LP386_002006"
     CDS             16735..17493
                     /locus_tag="LP386_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBL1919239.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            17506..18183
                     /gene="phoU"
                     /locus_tag="LP386_002007"
     CDS             17506..18183
                     /gene="phoU"
                     /locus_tag="LP386_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HBL1919240.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            18406..19437
                     /locus_tag="LP386_002008"
     CDS             18406..19437
                     /locus_tag="LP386_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBL1919241.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGKLMNSDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKNDGW
                     LFFFTSIFIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLLNKSILFVV
                     IGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYLTRP
                     YRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVIGSM
                     TNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPISVLF
                     FLTVRRLKR"
     gene            19434..20201
                     /locus_tag="LP386_002009"
     CDS             19434..20201
                     /locus_tag="LP386_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBL1919242.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALIVLPLTCVTTAYLFTKKKEQLKME"
     gene            20301..21869
                     /gene="liaX"
                     /locus_tag="LP386_002010"
     CDS             20301..21869
                     /gene="liaX"
                     /locus_tag="LP386_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HBL1919243.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDKASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQALEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDDEIAQVQL
                     STTTGSIYLKDTDK"
     gene            22045..22353
                     /locus_tag="LP386_002011"
     CDS             22045..22353
                     /locus_tag="LP386_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HBL1919244.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTKKRKEAEKIDDDEWSDF
                     "
     gene            22353..22703
                     /locus_tag="LP386_002012"
     CDS             22353..22703
                     /locus_tag="LP386_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBL1919245.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALFVAILM
                     SLVNVIVSEHNSRK"
     gene            22841..>23099
                     /locus_tag="LP386_002013"
     CDS             22841..>23099
                     /locus_tag="LP386_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1919246.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTL"
BASE COUNT         7609 a         3977 c         4971 g         6542 t
ORIGIN      
        1 gttagttcga gagctctttt ttttgctttg ctaccttgtt ccttgaagat tctgctgaat
       61 taagatagag ttaagttaac tacaagaatt ggagggatcc acatgaaatg gaaagaaaaa
      121 gtagacgaag cagctgaaaa gttatatgat ttggtcaaat cagaaaaata caatattgaa
      181 gtgaatattc cgaaaaaagg cggaaaagcg gtccaggtaa aatcaaaacg cccaacgaat
      241 catacaaaaa aatggatggc taaaaaccgc taataataac aaaagatcca taagtcggca
      301 ttttcatcga ttttagggtc ttttgttatt ttctaggttg aacatatcta aaaaattgtt
      361 tctgacaata ggagtaggga gaacgatgtg tgtctaaatc ctctgttgat ggatagaaac
      421 ctttatcttt ttcagttgtg aatcaggtat ataccagtta taatagaaga aacgaaagga
      481 cgggtgtacg ttatgtcgaa tcaattacct gtatatatac agattcatga ccaattaaaa
      541 aatgaaatcg aacagggtat atggaaagtc ggagaccgtc ttccttcaga aagagaatta
      601 gcagtgaaat tcaatgtcag ccgtatgacg ttgagacaag caattcaaaa cttggcagat
      661 gaaggaatct tagaaagaaa gatcggttcg ggtacgtatg ttgcgcgaga aaaagtacaa
      721 gaaaaaatgt ctggtgcaac aagttttaca gaaattatgg aatcacaaaa tcgagtaccg
      781 tctagtcgga caatctctta tttcttgact tcgccaagct caagtgaaat ggaaaaacta
      841 aacttgagta aagatgacac gatcttgcga atggaacgta ttcgtttcgc agatgatgtc
      901 cctatttgtt ttgaagttgc cagtgttcca caaaagctga tcgatggcta cagcaaagca
      961 gagattactg aatcgttgta tcgcacgcta gaagaaaaag gcgggaaaaa gatcggtcca
     1021 gcgaatcaaa cgattactgc tgtgttggct tctgagaaaa ttgctgacta tttagaggta
     1081 aaacgaggag atgcagttct tcgtttgcgc cagatttctt attttgaaga cggtacgccg
     1141 tttgagtatg tgcgtacgca atacgtagga aatcgttttg agttttattt ggaaaaataa
     1201 aaaacaggtg atccctgatt ccttattaga aataaaagag aatcagaatc acctgttttt
     1261 atatatgatc agttatcagt tgctcgtgat aagaaacaga accctcttca aattggactt
     1321 gtccgttcag cagctcaatg atggattctt taaagtggtc agcacttttt tcatctacag
     1381 cacagatgac gctaacttga tcagtatatt ggatttcttt tataaaaaaa tgttggagtt
     1441 caagataatt ctgtaatttt cctagttgcg gatacgtgat catcacagag atctcctgtt
     1501 gcaaggtacc ttctacgatt ccaatgtcag acaatgcttg agagaccgca tgagtgtatg
     1561 ctcgtattaa tccgcctgtg ccgagtttcg ttcctccaaa atatcgagtg actactgcag
     1621 ctacattgat cagttgattt tttttgagga cttccaacat cggtacgccc gccgttccac
     1681 ttggttctcc atcatcgctg cttcgctgga tttcattttt ttctccaatg atgaaggcgc
     1741 tgcagttatg gttcgctttc caatgttctt tttttatttc ttgaatgaaa ctttttgctt
     1801 ggtcctctga ttctattcgt ctaagagaac agataaagcg tgattttttg atctcaatct
     1861 cactttgtcc attttctttt attgtacgat agcgctcgat catcttgtca cctctttttt
     1921 tcattttctt tattcagtat aaataaagtt ctaggttgtt tcaacactgt aacggttgcg
     1981 caattgctgt agtatgcgat aataaagaca aaggcaggtg gatctgggga tgcaggaacg
     2041 aatgaaaaag tacgatgcaa ttacgcatta tttgaagaac aatggcggct ctcaagtaac
     2101 gttgaccttt acccaatttg acgaactgct gtttcccagt aacggacttc ccaaaacagc
     2161 aagggaaagt acagattggt gggcaaatga ttataaacac cctgaaaaag gtgcctatgg
     2221 ctggataaat gcaggctatg aagtagttgt catcaatttg gacaaagaat atgtcgtgtt
     2281 caataaatta gtgaaatcta gttggctatt tgattaaata aaccgcgttt agaaaacgtt
     2341 gacaaatttc tttcttttta tataatagag taacagacgc gaagaaaacg tttgcatagt
     2401 ttgttttaaa aaggagagaa aagtatggct aaaaaaacaa tcatgcttgt atgttcggct
     2461 ggtatgagca caagtttact agtaacaaaa atgcaaaaag ctgctgaagc aaaaggaatc
     2521 gactcggata ttttcgctgt gtccgcttct gacgcagata acaaccttgc aaataaagac
     2581 gtggatgtgt tgttattagg cccacaagtt cgctttatga aagctgattt tgagaaacgt
     2641 ctggaaccaa aaggcattcc tttagatgtc atcaatatgg ctgattatgg tatgatgaat
     2701 ggcgaaaaag tgttagatca agcaatcacg ctcataggtg aataaataga acagtataac
     2761 tatcgaacaa gcgatccaaa aaatagatcg cttgtttttt cgtatatttt tttagggcga
     2821 agaatatgaa tcatttttgg ggtagaaggc ttctgacgag agatattgaa gcaatagact
     2881 gtgaggaggt aaatttacca aattatgaga agatcgcagc agtggaacgt ttgggcaact
     2941 ggattctttg tcatcgctgt ggaatgagga cgtccgtcat tgatggacag cttgcagatt
     3001 acggttattt ttgtacacat tgtctatatt tagggcgatg cgacactcaa caagatttat
     3061 atttgtttga tcagcctgaa gcaaaacctc gagaagtcgt ctttttttgg acaggacagc
     3121 ttactgaaaa acaaacggaa atctcaaaga gaatactttg ccattcagaa aaaagacatc
     3181 atcttatttg ggctgtaaca ggtgcaggga aaacagagat gctttatcct attttagtgg
     3241 aaactttaaa agctggagga agagtagcga tttgtacacc gcgagtcgat gtttgtaatg
     3301 aattgttttt acgctatcgt tatgtttttc cagaagaaaa aatcacgttg ctccatggga
     3361 atacagcaac ggcttatacc tttacttctt ttgttatctg tacgattcat cagctatacc
     3421 gtttttatcg gtcctttgat ttaatagtga tcgatgagat cgatgcgttt ccttataacg
     3481 gggatgcagg attagctcat gctgtgcaaa cagcgattaa accagacgga cgattcatct
     3541 acttaagtgc cacacctgat aaaaagttac taaaggaaat caagcagacg tttgacatcc
     3601 acaaacttgc tttacgcttt catcggcgtt tgcttcctga acccgtcttg gttttcatga
     3661 ataattggcg acaaaaatgc aagaacaaga agaagataaa atctttggtg cggatcattc
     3721 atcaattaat taaagaaaac catatccttt tattttgtcc aagtatcacg atgatgcatc
     3781 gtttgaaagc cacacttcaa gaggctcttc cgagatatga gatcacagat gtttcttcaa
     3841 gagacaatca gcgggcggaa aaagtccaga aaatgcgaga agcaaaatat gatatactgt
     3901 taaccacgat gatccttgaa cgtggagtca catttgaaag aatatccgtt atcgttttag
     3961 gagcggatca tccggttttt actaaatctt ctttggtaca aatcgcagga agagccgatc
     4021 gtaaagggcc ttatacgaac agtcaagtat actttttcta tgaagaaaaa actgcagcta
     4081 ttcgaaaagc ttgtcaggaa atcaaagaaa tgaatgaaga agggaagaag atgctgtgag
     4141 gtgcagttgc tgcagtaaag atatcttcca aaatttaaca ttcagcgaga ttattggtgt
     4201 ttcgaaatac agattacctc agacttgttc agtttgtcgc gcacaatttc atttattgga
     4261 aacaagaggc tgttctggct gtcaaaaacc aatccatttc aatctagaga gtacgaaaaa
     4321 gaaagtaaag tctattcccg tttactgcag tgactgtcaa gaatggaaga agaaatatcc
     4381 gacctatgat tttcagcacc gtgccttttt tgtgtacgat gaaaatatga aggcctggct
     4441 caatcaatac aagtttatgg gagatatccg actagcaggc acctttgcat ataaatggac
     4501 gcagataaaa aaagaatacc cgacatacat ctattgtcca atacctttat ctgaaaaaag
     4561 gcgaacagaa agaggattca atcaagtaag cgagatgttg aaagcagcaa gaattccttt
     4621 tcagatgcta ctcaaaagag agaagcatct gctggctcaa gcaaaaaaca cgcgaaagga
     4681 aagattggag atgcctcaac cttttgaact tgcagtcacc ttttctaaga tacaaaataa
     4741 aaaaatattg attattgatg atgtctatac aacaggacag actcttttcc acgcagcaga
     4801 ttgtttgcag gtcgcacagc cgaaaatcat ccgaaccatt tctttggcga gatgaattag
     4861 atgtggaaat ttgatagcga tttaatttgc aaataaccta gagttcgata taatagaatt
     4921 aagaagaggg aaagagtggt ccttctcctt cttgattgtg gtagacgaaa ggggtaattt
     4981 ttatgtttag atataatgta cgcggcgaaa atatcgaagt aactgaagcg attcgcgact
     5041 acgttgagaa aaaagtaggc aaactagaac gctatttcag tgacgcaccc gatgcaacgg
     5101 cgcatgtgaa cttaaaagtt tatacagaaa aaacagcaaa agtggaagta acgatcccat
     5161 taccttatct tgtattacgt gccgaagaaa cttctccaga tttatacgca agtatcgatt
     5221 tggttgttga taaattggaa cgccaaatcc gcaaattcaa aacaaaaatt aatcgtaaat
     5281 cccgtgaaac gggcatgaat actgcagatg ctgctgcttt attcaatgaa gaggacgaaa
     5341 acgaaaatga ttctgaatta gatatcgtac gtacgaaacg cctttcattg aaaccaatgg
     5401 atagtgaaga agcagtctta caaatgaaca tgctgggaca taacttcttt atttttgaag
     5461 atgcagaaac aaatggtaca agtatcgttt accgccgtaa agatggaaaa tacggactga
     5521 ttgaaacaga ctgatcagcc ttacttaaat aacaacgaaa acttgcagca gctactgaca
     5581 gctgccgcaa gtttttttga gtttcctcct cttttagatg aaatatgaat aaattatgaa
     5641 gttcttactt taatacgctt aagatatttc aattatctat aactaatgat aaaatgaaaa
     5701 gtaaagtcta catagtctgg ataatacaca gaaggaaaag gagattacac aacgcatggc
     5761 caatttgatt cgttcactta tcgaaaacga taagaaagaa ctaaaacgtt tagatagcat
     5821 tgcaaaaaaa gttgaagcat acgctgacca aatggcagca ttaactgatg aacaattaca
     5881 ggcaaaaact gctgaattca agggcagata ccaaaaagga gaaacattag atcaattact
     5941 tccggaagct tttgcagtcg tccgagaagc agcaaaacgt gtattggggt tatatccata
     6001 ccacgtacaa ttgatgggtg gaatcgtgct tcacgatgga aatatccctg aaatgcgtac
     6061 tggtgaaggt aaaaccttga ccgcaacgat gccagtatat ctaaatgctc tgactggcga
     6121 aggggtacac gtagttaccg tcaatgaata tttagcaacc cgtgactcga cggaaatggg
     6181 cgaactttat aatttcttag gattaacagt ggggttgaat atcaactcaa aatcttcgga
     6241 tgaaaaacgc gaggcttata attgtgatat cacttatagt acgaataatg aattaggatt
     6301 tgactacttg agagacaata tggtcgttta ccgccatcaa atggtacaac gtccgctgaa
     6361 ttatgccatt gtcgatgaag ttgactcaat cttgattgat gaagcgagaa cgccgctgat
     6421 catttcaggg caagcagaaa aatccacagc tttatataca agagcagaca acttcgtgaa
     6481 acgtttgaaa gaagaagaag attataaaat cgatgtacaa tcaaaaacaa tcagtttaac
     6541 cgaagcaggg atcgaaaaag cagaagaaac attcggtttg gataacttat acgacattga
     6601 aaatactgca ttgacccatc acttggatca agcattgaga gccaactata tcatgctttt
     6661 agatatcgat tatgttgtcc aagacggaaa agtactgatt gttgaccagt tcactggtcg
     6721 gatcatggat ggacgccgtt attcagatgg acttcaccaa gcaatcgaag ctaaagaagg
     6781 cgtagagatc gaagacgaaa cgaaaaccat ggcgacgatc actttccaga actatttccg
     6841 tatgtacaag aaacttgcgg gaatgactgg tacagctaaa acagaagaag aagaattcag
     6901 agaaatttat aacatccaag tataccagat tccgacaaat cgtccggtta tccgtgatga
     6961 tcgtccagat ttactttacc caacattaca aagcaagttc cacgctgtcg tgcaagatat
     7021 caaagatcgc taccgcaaag gtcaacctgt gttagtcgga actgttgcgg ttgaaacatc
     7081 tgagttatta tcagatatgc tgaatcaaga acgtattcct catgaagtgc tgaatgcgaa
     7141 aaatcacttt aaagaagcag agatcatcat gaatgctggt caaaaaggtg ctgtgacgat
     7201 tgctaccaac atggctggtc ggggaacaga tatcaagtta ggacttgggg taagagaact
     7261 tggtggtcta gcagttatcg ggacagaacg acatgaatct cgtcgtatcg ataaccagct
     7321 tcgaggacgt gcaggacgtc aaggagaccc tggtatgtca caattctact tgtcattgga
     7381 agatgatttg atgaaacgat tcggttcaga acgaatcaaa gctttcttag atcggatgaa
     7441 gatcggtgag gaagatgctg ttatccaaag caagatgctg acgaaacaag tagaatctgc
     7501 acaaaaacgt gtagaaggaa ataactatga cacacgtaaa aacgtcttac aatacgatga
     7561 tgtgatgcgt gaacaacgtg aagtaatcta taaacagcga caagaagtaa tcatggaaga
     7621 aaaaagctta tccaagccac taatgaacat ggtcaaacgg acaatcagtc gtgtagtaga
     7681 tgcgcataca caattagaga aagaaaattg gaatttggaa agtatcatcg attttgccgg
     7741 cagtactctt gtccatgaag atagtattac tcttgcagat atcgaaggaa aaacatctca
     7801 ggagatcaaa gagtatctaa acgaacgagc acaagaagta tttaatacca aagcggctca
     7861 actaaatggt ccagagcaac tgttggaatt tgaaaaagtc gtgatcttgc gtgttgtgga
     7921 ctctaaatgg acagaccata ttgatgcaat ggatcaatta cgtcagtcaa tcggcttacg
     7981 tgcttatgga cagaacaatc cattagtcga atatcaaaca gaaggctata agatgtttga
     8041 agatatggta ggcgccatcg agtatgaagt cactcgaatc tttatgaaag ctgagatccg
     8101 tcaaaacgta cagcgtgaac aggtttctca aggaacagct tctcactcag aagacggaga
     8161 tgccaaagaa aatagtaata ctagcgcgaa aaaacagcca atccatgtga acaaggtcgg
     8221 aagaaatgat ccttgtcctt gtggaagcgg gaaaaaatat aagaactgtc atggaaaaaa
     8281 tgcaaactaa tttctgacag caggattggt gagacaaatt ctttttttaa gaattcgtct
     8341 caccttcttt ctgttatttg ctgattctgt tagactagat ataatgaaaa aagtatagtg
     8401 aaagaaggaa aaaacatgga aatatccgaa attcgaaatc tcctgacaga aatgcaggaa
     8461 aaggtcacaa gtttcaggag gtctctttga cttagatcag ctggaagaag acatcgcgga
     8521 agcagaagca aaaatggctg aacctggttt ttgggatgac agcgaagccg cacaaaaagt
     8581 gatcagcgaa aataacgcta ataaagaaac ctatgaccaa ttccattctc ttgccgaaga
     8641 actagaagaa atcgaattga tggtggagat gctgcaagaa gaacctgatg cagcaatgca
     8701 agaagaagca gaaacacgta tcaatgcatt agatgaaaaa atgaagacgt atgaattatc
     8761 tatgctgtta gacggacctt atgatcgaaa caatgcgatc gtcgaattgc atccaggggc
     8821 tggcggaacg gagtcccaag actggggcag catgctttta cgtatgtata cacgttgggc
     8881 agagcagcat ggctatcaag tagaaacact agattatcaa gcaggtgatg aagcagggat
     8941 caagagtgtg accctgctga ttaaaggaca taacgctttt ggttatctaa aatcagaaaa
     9001 aggtgttcat cgccttgtac ggatttcgcc ttttgactca gcgaaacgac gtcatacttc
     9061 tttttgttcg gtagatgtga tgccagagct tgatgaaacg atcgatatag aaatcaatcc
     9121 agatgatttg aaaatcgata cgtaccgagc aagtggtgca ggtggtcagc acatcaataa
     9181 aacagaatct gctgtacgga tcactcactt gcctacagga acagtagtag ctagtcaggc
     9241 acaacgctca caattgaaaa accgtgagca agcgatgggg atgttaaaag ctaagcttta
     9301 tcaattagaa gtggaaaaga aagaacaaga agcagctgca cttcgaggag aacaaaaaga
     9361 aatcggctgg ggttcacaga tccgttctta tgttttccat ccctattcta tggtaaaaga
     9421 ccatcggaca aacgtagaga caggaaatgt ccaagcagtt atggacggtg accttgattt
     9481 atttattgac ggctatttaa aaatgcatct acaataagaa ctcattgtta aattgaaata
     9541 aaattgtaag attttgcaag catgttgaaa cattgccatg ctataatagc taaagactga
     9601 aaaagatatg gagagaacgc catgattgaa atgaaggatg taatgaagaa gtactcaaat
     9661 ggtacgaccg ctatccgcaa tctctcgatt gtcatcgaac aaggagagtt tgtctatgtg
     9721 gttggtccgt ctggagccgg taaatctaca ttcatcaaat tgatgtatcg agaagaaaaa
     9781 gcttcaaaag gaactttgaa cgtcgcaggt catgatctaa tagcaatcaa aaaccgcgaa
     9841 gttccttatc tacgcagaga aatcggcgtg gtgttccaag actataaatt attaccaaga
     9901 aaaacagtat atgaaaatgt tgcgtacgct atgcaagtta tcggcagaaa acctcgagat
     9961 atcaaaaaac gagtaatgga agtgctggac cttgttggtt tgaaacacaa agttcgagtc
    10021 tttcctagcg aattatccgg tggggaacag caacgtgtct ctattgctcg ggcaatcgtg
    10081 aatacgccta aagtacttat cgcggatgaa ccgacaggaa atctggatcc agaaaactca
    10141 tgggaaatca tgaaattatt agatcggatc aatgcccaag gaactactgt cgtgatggct
    10201 acacataaca gtacgatcgt aaatacgatt cggcaccgag taattgctat cgaaaacggc
    10261 cgcattattc gagatcaagc ggaaggggaa tatggatacg atgattagaa cctttttccg
    10321 ccatttatta gaaagtatca agagtttgaa acgtaacggc tggatgacag ttgcttcagt
    10381 cagtgcggta acgatcacgt tgactttagt cggtgtattc atggcagtta tcatgaatgc
    10441 aactaaatta gctcaggata tagaaggaaa cgttgatgta tctgtattcg tagatatcgg
    10501 tacaaaagac gaagagatga aaaagctaga aaaagaattg aatgacttag atcatgttaa
    10561 aaaagttgaa ttttcaagca aagaacagga attgaaaaaa atccaaaacg aaatgggtga
    10621 ttcctggaaa ttgtttgaag gtgacaataa cccgttatat gatgtgtatg tagtaagtgc
    10681 tactgatcct tcttatacaa aacaagtagc agaagaagca gcagatttga agaatgtttc
    10741 tcgttctgat tacggtggag cttcctcaga tcggattttc caaatcgctg gtgcagttcg
    10801 gacatgggga ttagttgcag cggcattgct gctgttcgta gcgatgtttc tcatttcgaa
    10861 cacgattcgg atcacgattt tgtctagaca gcgtgaaatt caaatcatgc gtttagtcgg
    10921 tgcaaaaaat ggatatattc gctggccgtt tttccttgaa ggtggctgga tcggtctgat
    10981 cggtgcgatt cttccgattt tgatcatcac atttggttat gcatggtttt tccaattgat
    11041 caatccatca ttattacgtt cccattattc attgattcgt ccacaaaata tcgtttggaa
    11101 aatcaatctt ttaatggtcg gcattggtgt gatcattggt tcacttggct cgatcatttc
    11161 tatgagacgt tttttgaaat tctaatacca caatataaat aaaatgagaa agttggacag
    11221 tttcgttcca gctttctttt tttattggct aggagaatag aaggaagcgg cttttttccc
    11281 tttactttaa aaaacaactt gggtattctt aagttggtag aagaagaggt gaagccgtga
    11341 aaattatcgt tgacaatttt tttacgatcc ttttgattat gaatattttg ctttccttta
    11401 tcatcgtttt tcgagaaaga aaggaaactg ctcaaacatg ggcatggctg ctcgttttga
    11461 tgttcattcc agttgtagga tttattttat atattttttt aggaagaggg atttccaaag
    11521 agaaaatctt tgatttgaag atccaaggga aaatcggtaa gaacctggaa attgaagaag
    11581 acaaacaggc attgatgcga gggctttatc ctcatccgcc tactggacaa gtagatgtga
    11641 aacaattgat ctatatgctc acggtatttg aaagtacgct ctatacgact aaaaatgaaa
    11701 tcactttatt tacagatggt cgtgaaaaat tcgatgcgct gattgaagat atcaagcagg
    11761 cagaagacca tatccacttc cagtattata tttatcgcag tgatgcatta ggtgaagaag
    11821 ttcgagatgc attgacagag gcggcaagac gaggggtaaa agtcagagtc cttcttgatg
    11881 catggggttc cacacaagtt tcttccagct tttttcagaa tttgaaaaaa gcaggcggag
    11941 aagtcgcatt tttctttcct ctatttgttc cgtatattaa tcctcggatc aattatcgca
    12001 atcatcgtaa aatcgtagtt attgatggga aaatcggata tacaggtggg ttcaatgttg
    12061 gaaatgaata tctaggattg gtaaagaaat ttggttattg gcgagacaat catttgcgta
    12121 tttacggaga agcggtgtat accttgcaaa accgtttttt gatggactgg aattctcagc
    12181 atacaaaaga agtaggctat tctcccaaat ttttcccgtc cattcacact actggtgata
    12241 tagctgttca aatcgtgaca agcggaccag ataccgaaca tgaacaaatc aaaatgactt
    12301 atttgaaaat gatttcgtta gccaaacggg agatattgat ccaaacgcct tattacatac
    12361 cggatggatc gattcatgaa gcactgaagt tggctcttct ttcaggcgta aaagttcata
    12421 tccaaatacc taacaaacca gatcatcttc tcgtttactg ggcaacgtat tctttcgctg
    12481 cagagctgat cgagtatgga gcaaggatcg aaacatatga gaatggattt attcatgcaa
    12541 agacgatgat tatcgatggt ggcattgttt cagttggctc agcaaatatc gatgttcgtt
    12601 catttcgctt ggactttgag gtcaatacac tggtttatga tgaacgaatg gcttcacgtg
    12661 taagaaaagc tttttttgaa gactcgaaaa tttctacgca tctcacaaaa gaaatgtatg
    12721 aaaaccgagg aataatcatc aagatgaaag aaggattagc aagattgatt tcgccgctcc
    12781 tttaaaacat aaaaaggaca tgagaaccat caacagatgg agatctcgtg tccttttcta
    12841 acggggccat ttctgagagt acgtcagaaa tggagaaagc gtctcgcatg agcgaaatta
    12901 actttggggt atctcttgtt ttttggggaa agcaagaaat aagctaatat atgctattaa
    12961 aagagacaca tttcaaagcc agtatagcat agaaactttt aatgagatag ttttttttac
    13021 aattatgaga atttattttg ttatttaatg attttgattc gttttcatca agtaatgaaa
    13081 atgataaaat aaacatactt taggattaaa ggagatttct aatgaaaaaa cttaaattat
    13141 tcttaccaat aataggatta gccattcttt tatcaggctg ttcaaagtgg attgatcgag
    13201 gagaatccat tacggctgtt ggctcttctg ctttacagcc tttagtagaa acagttgctg
    13261 aaacttacca gacagaaaat cctggaaaat tcatcaatgt acaagggggc ggaagcggaa
    13321 ctggtttgtc tcaagtacag tcaggagcag tcgacatcgg aaactctgat ttgtttgcgg
    13381 aagaaaaatc ggggatcgat gcctcagcat tagtcgatca tcgagtagca gttgttggga
    13441 tcactcctat tgtgaacaag gatattggcg taaaagacat cagtatggaa aacctgaaaa
    13501 aactatttac aggcgagatc aaaaactgga gtgaagtcgg tggaaaagat cagccagtag
    13561 ttatattgaa ccgcgcttca ggaagcggaa cccgtagcac gtttgaaaaa tgggtattgg
    13621 acggagaaac agctgttcag gcacaagaac aagattcaag cggaatggtg cgccagatcg
    13681 ttgccgacac acccggtgca atcagctatg ttgctttttc ttatgtttcc gatgatgtag
    13741 atacgttgaa tgttaacggt gtagaaccga cagatgaaaa tgtgacaacg aacaaatgga
    13801 cgatttgggc atatgagcat atgtacacaa gagatcatcc aaaaaaactg acaaaagaat
    13861 ttttagacta tatcttatct gatgaagtac aagataacat cgttggagaa ctaggttata
    13921 tccctgtttc tcatatgaaa gtcgaacgtg attggcaagg aaatatcgtt aaagagtaat
    13981 ctttacacaa aatttacaaa cttagctaaa cttttacatg ttattaaaac caaattgatg
    14041 ttcaatttgt acactgagtg agtatgttaa acctgattaa gggggagtca tctgtggaag
    14101 atgtgaaaaa agtattatta acaaaatcaa aacgttcaaa aatggaacag cgtggaaaat
    14161 tcatcagttt tttatgtatc gcgctgatcg tgttggttgt attatctatt ttttattttg
    14221 tagctagtaa aggattggcc acctttttta ctgataagat caatgtattt gattttctgt
    14281 ttggtacaga ttggaatcca agccaaatcg gagcaaatgg gaaaccaatg gtaggggcat
    14341 tgcctatgat cacaggttcg tttattgtga cctttttatc tgctatcgtt gccacgccat
    14401 ttgccattgg tgcagcagta ttcatgacgg agatctctcc taaaaacgga acgaagatct
    14461 tacagccggt catcgagctg cttgtaggta ttccttctgt cgtttatggt tttatcggtt
    14521 tatcagttat cgtgcctttt gtcagaagta tttttggcgg gacagggttt ggtatcttag
    14581 ctggtacatt tgtgttgttc gttatgatct tgccgactgt cacaacgatg actgttgatg
    14641 cattaaaggc agtaccacgg cactatcggg aagcttcatt agcgcttggt gccacaagat
    14701 ggcaaacaat ctacaaagtc gtgctacgag cagccgtgcc cgggatttta acagcagtcg
    14761 tttttggtat ggctcgtgcg tttggtgaag ccttagctat ccaaatggtc atcggtaatg
    14821 cagcattgat gccaacagga cttactactc ctgcttctac attgacgtcc atcttaacaa
    14881 tgggaatcgg aaatacaatc atgggaacag ttgaaaataa tgtgttatgg tcattagcgc
    14941 tgatcttgct attgatgtca ttattcttta atatcgtgat ccgtatgatt gggaagaaag
    15001 gagagctgaa ataatgaacg caaaacgctc agataaaatt gctacaggtg ttttatatat
    15061 agtttcgggg atcatcgtat tgattttagc agctttacta ctttatatct tagttcgggg
    15121 aataccgcac atttcatggt ccttcttgac cgaaccttcc aaagcctacc aagaaggtgg
    15181 tggaatcggg atccagctat ttaactcgat ttatttgctt ttgatcacga tgatcatcag
    15241 ttttcctatt tctttaggtg cgggtatcta tctttcagaa tatgctggaa aaaactggct
    15301 aacagatgtg attcgcacgt cgattgaaat cttgagctcg ttgccttctg tcgttgtcgg
    15361 tttattcggt ttcttggttt tcgttattca attccagtat ggtttctcga ttatttctgg
    15421 tgcattggct ttgactgtat tcaacttgcc tcttttgact agaacagttg aggagtcttt
    15481 acaagcggtc cattacacac aacgagaagc aggattggcc ttaggtttgt cacgctggga
    15541 aacagtgatg aaagtggtgg ttccagaagc gacaccaggg attttgactg gtgtgatcct
    15601 aagttctgga agaatttttg gtgaagcagc tgcattgatc tatacggctg gacaaagtgc
    15661 acctgcgtta gattttacga actggaatcc attaagtgtt tcaagcccga tcagcatttt
    15721 ccgtcaagct gaaacattag ctgtccatat ttggaagatc aatacagaag gcacgatgcc
    15781 tgatggtgtt tctgtttcgg ctggcgcttc tgccgtgttg atcattgctg ttttactgtt
    15841 caacttcggc gctcgtgcga ttggcaaacg attataccga aaaatgactt cagcctaagg
    15901 agaagaagca aaatgaaaaa atataactgg aatgaaacaa atgtcatcac catgccaaaa
    15961 gagaaagaag tagcactata tacggatgat atacatgtct ggtatggcga caatgaagca
    16021 atcaaaggag tggatctgga atttgaaaaa aataagatca ctgcactgat tggtccttcc
    16081 ggctgcggaa aatctacgta tcttcgttcg ttgaatcgaa tgaatgatgg gatcgctaat
    16141 acgaaaatca ctgggaaaat catgtatcaa ggcgtagata ttaatgcgcc tcaagtggat
    16201 gtttatgaga tgcgcaaacg gattggcatg gtttttcaac gtcctaatcc gttcagcaag
    16261 tcgatttatg acaatattac atttgctttg aaacagcacg gcgaaaaaaa caaaaagaaa
    16321 ttagatgaaa tcgttgaaac aagcttgaaa caagctgcct tgtgggacca agtaaaagac
    16381 agcttggaca aaagtgcctt ggctttatct ggcgggcaac agcaacgttt atgcattgct
    16441 cgtgcgatcg cgatgaaacc tgatatcttg ctgctagacg agccggcaag tgctttggac
    16501 cctatttcga caggaacggt tgaagaaaca cttgtaaact tgaaagaaga ctatacgatc
    16561 atcatcgtga cgcataacat gcaacaagca gctcgtatca gcgactatac tgcctttttc
    16621 tatctaggaa aagtaatgga atatgacaaa actaacaaga tatttaccag accaaaaatt
    16681 caggcaaccg aagattatgt gtccggtcat tttggttaag acggaggcct caacatgaca
    16741 aaagaaatta tttcatctaa agatcttcat ctgtattatg gaaagaaaga agcactaaaa
    16801 gggatcgatc taagtttcaa tcaaggggaa atcactgcga tgatcggtcc ttctggttgc
    16861 ggaaaatcca cttatctgcg ttctttgaac cggatgaatg acctgattcc gaatgtaacg
    16921 atcaccggaa gtgttttata taaagacaaa gacatctatg gtccaaaaac agatgttgtt
    16981 gaactaagaa aagaaatcgg catggtattc cagcagccaa acccatttcc tttttctatc
    17041 tatgaaaatg tcatctatgg attgaaatta aaaggggaaa aagataaaaa agtccttgat
    17101 caagtagttg aagaaagcct gaaggcagcg tctgtttggg atgatgtgaa agacaaattg
    17161 cataaaagtg ctttatcttt atccggcggg cagcagcagc gtgtatgtat cgcacgtgtt
    17221 ttggcagtta atccggaaat catcttattg gatgaaccaa caagtgcgct tgatcctgtt
    17281 tctactggga aaatcgaaag tatgctgtta gaattaagag agcggtatac gatgatcatc
    17341 gtgacccata atatgtctca agcttcacgt atttcagata agacggcatt ctttttagat
    17401 ggtcacttga tcgaatacaa cgatacgaag aagatattca tgaatccaga aaaacaagag
    17461 acagaagatt atatttcagg tcgatttgga taaggaggaa acggaatgct acgtacacaa
    17521 tttgaagaag aattgctgaa tctccataat cagttctacg aaatggggat gatggtgagc
    17581 agcgccgtgc acaagtcagt tcgtgcatac atcaaacacg ataaaatctt agcccaagaa
    17641 gttatcgaaa acgatataaa tatcaataac atggaaacac gcttggagaa gaaaagtttt
    17701 gaaatgatcg cattgcaaca gccagttaca actgatttgc gtatgatcat tacggtcatg
    17761 aaagctagct cggatttaga acgtatggcc gatcatgcgg tgtctgttgc taaatccacg
    17821 attcgcgtaa aagggcagac gagaataccg gaaatcgaaa aagagatctc cgatatgtcc
    17881 gattatgtga aaaaaatggt ggacaacgtc ctagttgctt atgtcaaaac agacgaaaaa
    17941 gacgcacgta cgatcgccaa tatggatcaa agagtcaatg actatttcaa tcgaatctat
    18001 aatgcaacaa tcaaaaatat gcaggaaaat cctgagacag tcatcagtgg aacagactac
    18061 ttgaatgttg ccagttatct agaacggatc ggagactatg tgacaaacat ctgtgaatgg
    18121 atcgtctact tggctacagg gaaaatcact gagttaaata cgaaccacaa tgagattttc
    18181 taaactgaag ctgtgattat gccgtttgtt tatgaaaaga ggttgtgaaa aagctgttct
    18241 acatcaagta ataagaacag tcaaacaaaa aatagctcct catatttttc gtttggctgg
    18301 acttattacc gcagatgcaa gcttttgaac accgtttatt cgggaaaggg tttgtgacaa
    18361 aacatgtcac aaaccctttt catcatttca tagaaaggat aaagaatgca aaaaaaaatt
    18421 agcatcatca ctatattttt tatttgtgtg cttacttcat gggttattca gcatcaagcc
    18481 gctttatatg aagtacctgt catcgagata gaaaaagtac gaataaaaga ggatcatcaa
    18541 ttgattacag gaaaactgat gaactcggat caaaaaggag aatcgattta tttatcggtt
    18601 ccttatcaaa aaaatcaaat agaaacagca aatataaaag cgagacaaat gtatctagtc
    18661 caaatgcatg gagatgaatg gcagctagta gcaaaaaaaa atgatggctg gcttttcttc
    18721 ttcacaagta tcttcattgg cgccatgttg cttattggcg gaaaacaggg tctatttgct
    18781 ttaggaagtc tcatcatcaa tatcgtttta cttttacttt tgttgctcat ctttactaaa
    18841 acagaaggga tttctctatt aaataaatct atcctgttcg tcgttatagg gatgattatt
    18901 agcatactgg ctttagatgg atggaataga agcagtataa tcaaaatttc agctgcagtt
    18961 acgagtgttt ttttagcatt ttttatttgt cttttgacaa tgaatcattg gaaagaccaa
    19021 ggactgcgct atgaggaact gaattatctg acacgaccgt atcgttctgt ttttctttct
    19081 agcgtactga ttggaacagc tggaggaaca ctcgataccg ttatcacagt cattgcgaca
    19141 ttagaagaat tgactaagcg acaaccagaa ataacagcga aacagttatg gctttcagga
    19201 aggcaagtgg gtcgagatgt gattggctcg atgaccaata tccttttgtt cgtctatatc
    19261 agtgggtcag ttccatcgct tcttttatat ttaggaaatc aatggtcttt caaagaaacg
    19321 atagaacagc atttatcatt ggaattttta cgcgtcattg ctggcagctt aggaatagta
    19381 ttatcgatcc ccatctcggt cctctttttt ctgactgtaa ggaggctgaa acgatgaatg
    19441 tacttattat acttgttggg attttagcaa tcagcgtgct acttattggc ggtacgcaag
    19501 gtatgtatat tcttttaggc ttattcatca atttagggat ctttttcctg ttgttattcg
    19561 gttatcatca gaagtggccg atactggcat tgtcggtcat aggattttta ttgattgctg
    19621 tggttatctt attttttatc aacggttata atctaaaaat gcgtgcagct tttgtgagta
    19681 tactgatctt tttattttgt ttcctactat tgcttcctat cactgatttt ttagcgatcc
    19741 aaggttttac atcggtagaa ctagaagaat tatctggctt agataagact ttagcgattg
    19801 attttagatt acttacgaga tcgttgcttc tgattagtct tagtggtgct gttttagatg
    19861 cgagtgtagc aatttctagt gggacattcg aagtatatca ggcaaatccg caattatctt
    19921 tttaccaatt gcgccattct agtttcgcta ttgctaaaaa aatattggcg tcaacagtaa
    19981 tgacacttct ttttgcattc atgggaagtt ctttagcgtt gatcctctgg tttattgatt
    20041 tagacattcc ttttcagcaa gtgatcaatg aaaaatcatt tgttctagaa tatacgatgg
    20101 ctattcttac cacattgtcc gcactaattg ttcttccttt aacctgcgtg actacagcat
    20161 atctctttac aaaaaagaaa gaacaactca agatggagta aaagttacaa cttaagtcct
    20221 atgacatttt tactgaatca gtgcataata tggatgtaag gaaaagcttg caaacaattt
    20281 tgcttaagga ggcaatttcc atgaaagaaa gagaacgtat tttagattta gtgaaaaaag
    20341 gaatcctttc gactgaagaa ggcttagatt tattagaaag catggcaact gaaaaagacg
    20401 aaaagcaaat caaaaaagaa gcagacaagg taactgctag tcataaagaa aaagataagg
    20461 caagtcaatt gatcgataaa cttgaaaacg gcgaagaaga aatttctgag ccagttgatc
    20521 caaaggaaag agaaagacaa gatcaagaaa acttagaaaa gatcttagat gaactagcaa
    20581 ctgaagcgaa taaaacttcg gcgcgtctag atgaagtaaa tgctcaattc gctgacaata
    20641 aggcagcacg caatgagaaa caggaagcat tgatgcagct gaatacaaaa gaagaattag
    20701 gcgagttgac agaagaagaa ttagcacagc gtcaggcgtt agaggcagaa atcaaagagt
    20761 tagaagctag tggcgataca ctgttagaag aacaattgaa attagaagca gaattaaaag
    20821 atatccgtaa gaatcaatgg tctgagaaaa aagaaacgtt tactgataag tttgaattgc
    20881 cagatgattg gaaagatcaa gcaacagata cactgaatca agtaggcgaa aaaatgtcag
    20941 aagctggatc acagttaggc aaattcttga agaaaacatt ccaaactgtt tcagaaacag
    21001 tgaatgacaa catggaatgg aaagatgtca gcttacgtgt ccctgggatt gcgacaacga
    21061 aatttgagca tgaattttac tatgaagctc ctgcagcaag tatccttgat atcaaggcag
    21121 caaacggaaa cgtgacgtta aaaacgtggg acagcaacga tgtgaaagtt gaagctaaga
    21181 tcaaacttta cggaaaaatg ggtgctgaac catttgaagc attctctgaa cggagccaga
    21241 ttgaggttaa tgaagatcat atctccttcc aaattccaaa taaacgtgtg cgtgcagacc
    21301 ttgttttcta cttacctaaa cgagtatacg accacgcagc tattaaactt ctaaatggca
    21361 acatcatgat tgaaacattg gaagctaaag atatttatac aaaatctacg aatggtaaca
    21421 tcatcgtgga ccaattaact gcaacgatgc tggaagtaga aggtgtaaac ggcaatatcg
    21481 atattcgaaa cgggaacatc ttagattcta ttatcgaaac agtaaatggt acagtgacat
    21541 ttggtgcgac agcagaaaat ctttctgtgt ctttagtaaa tggtgatgta cgtcttacga
    21601 ttaaagaaga taatttgaaa aaagtagaag caagttcagt gaacggaaat gtcaaagtcg
    21661 ctttaccaga tggcatcggt ttggaaggac atgctaaaac aagtcttgga agtatcaata
    21721 gccgtctgtc caattacgaa gtagttcgtg agaaaaaaga acggacaaac caaatgttgc
    21781 aattccgtcg tgtttcagat gatgagatcg cgcaagtgca actttcaacg acaacaggaa
    21841 gtatctattt aaaagataca gataaataaa gaggttgtga aagagatgtt cagccttgag
    21901 caataagaag cgattttgta aaatagcttc ccctatttta caaaattgtg ccttattgcc
    21961 gataggctat ctcttgaaca ccgattaaga agaaggttgt cacaacgatt ttcttcattt
    22021 aaaatagtag aacagaggtg agacatgatg aaaaaaaagt tgacaaaatc caataaaaat
    22081 gttgttttga caggtacttt agcagggatt ggggaatata tcgggattga tcccactgtt
    22141 atccgtgtgc tttatgtatt cctaagctta gttgcttttg gaagtccaat cattttatac
    22201 attttattag ctttgattat cccatctgcg cgttctgcac gaacaaacta tggacataac
    22261 aatgcatatt atgaaaaaaa caattatcgt gaacaaacaa aaaaacgcaa agaagcggaa
    22321 aaaatcgatg atgacgaatg gagtgacttt taatgtcgta ctttcagcgt attttggtta
    22381 atacgttaac attcatatcg ttggctgttc tttttcctgc gatggtccat gtgagcagta
    22441 tttggacagc cgtccttgcc agcttcgtat tatctgtgtt gaacatgttt gtcaaaccga
    22501 ttctgacgat cctgtccctg ccctttacat tagtcacatt gggattgttt acgtttgtta
    22561 tcaatgcagc gattcttaaa atgacttcct tttttgtagg agcagaacat tttagttttt
    22621 cttcatttgg tgcagcgtta ttcgtagcta tcttgatgtc acttgtcaat gtaatcgtta
    22681 gtgaacataa cagcagaaag taaaaaaagc tgtgccgaga tctcggcgca gcttttttgt
    22741 ttatcgcgaa ttgtaaaatt aagttagaaa aataaaaagg catttatggt acactcaaat
    22801 tgtatttccg acgaaagaaa acaaaggagt gtaaccataa atgacctaca aacatcttac
    22861 catagacgaa ctgacaatga tagaatcata ttatcttcaa cataataagc cggttgaaat
    22921 cgctaaccga atgggacgtg ctatacaaac tatttataat gtagtcaata agttcaagca
    22981 aggtaagact gctcttgatt attggcacca gtataaagaa aataagaaaa aatgtgggag
    23041 aaaagtcatt caattacctg ctcatgaggt agattacatt aaagagaaag tcactcttg
//
LOCUS       DAFEKH010000046        22857 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.047, whole genome shotgun sequence.
ACCESSION   DAFEKH010000046
VERSION     DAFEKH010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22857
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.047"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(104..1336)
                     /locus_tag="LP386_002014"
     CDS             complement(104..1336)
                     /locus_tag="LP386_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBL1919247.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1591..2160
                     /locus_tag="LP386_002015"
     CDS             1591..2160
                     /locus_tag="LP386_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL1919248.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2338..2778)
                     /locus_tag="LP386_002016"
     CDS             complement(2338..2778)
                     /locus_tag="LP386_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBL1919249.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            2936..3700
                     /gene="map"
                     /locus_tag="LP386_002017"
     CDS             2936..3700
                     /gene="map"
                     /locus_tag="LP386_002017"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HBL1919250.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3732..4655
                     /locus_tag="LP386_002018"
     CDS             3732..4655
                     /locus_tag="LP386_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HBL1919251.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            4731..5870
                     /locus_tag="LP386_002019"
     CDS             4731..5870
                     /locus_tag="LP386_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HBL1919252.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            5863..6663
                     /locus_tag="LP386_002020"
     CDS             5863..6663
                     /locus_tag="LP386_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBL1919253.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            6663..7490
                     /locus_tag="LP386_002021"
     CDS             6663..7490
                     /locus_tag="LP386_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBL1919254.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            7468..8202
                     /locus_tag="LP386_002022"
     CDS             7468..8202
                     /locus_tag="LP386_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL1919255.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            8302..9168
                     /gene="rfbA"
                     /locus_tag="LP386_002023"
     CDS             8302..9168
                     /gene="rfbA"
                     /locus_tag="LP386_002023"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBL1919256.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            9182..9754
                     /gene="rfbC"
                     /locus_tag="LP386_002024"
     CDS             9182..9754
                     /gene="rfbC"
                     /locus_tag="LP386_002024"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HBL1919257.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            9776..10804
                     /gene="rfbB"
                     /locus_tag="LP386_002025"
     CDS             9776..10804
                     /gene="rfbB"
                     /locus_tag="LP386_002025"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBL1919258.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            10902..11753
                     /gene="rfbD"
                     /locus_tag="LP386_002026"
     CDS             10902..11753
                     /gene="rfbD"
                     /locus_tag="LP386_002026"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HBL1919259.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            11787..13820
                     /locus_tag="LP386_002027"
     CDS             11787..13820
                     /locus_tag="LP386_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919260.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            13864..15143
                     /locus_tag="LP386_002028"
                     /pseudo
     CDS             13864..15143
                     /locus_tag="LP386_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
     gene            15353..16159
                     /locus_tag="LP386_002029"
     CDS             15353..16159
                     /locus_tag="LP386_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1919261.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            16171..17391
                     /locus_tag="LP386_002030"
     CDS             16171..17391
                     /locus_tag="LP386_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1919262.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            17381..18967
                     /locus_tag="LP386_002031"
     CDS             17381..18967
                     /locus_tag="LP386_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBL1919263.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            19006..21144
                     /locus_tag="LP386_002032"
     CDS             19006..21144
                     /locus_tag="LP386_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL1919264.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(21512..22495)
                     /locus_tag="LP386_002033"
     CDS             complement(21512..22495)
                     /locus_tag="LP386_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HBL1919265.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
BASE COUNT         7176 a         3899 c         4712 g         7070 t
ORIGIN      
        1 aaaaaacggt ggggttgttt agcgaaataa aggatctaag ccaatagctt agatccttta
       61 ttctatgctt tatattattt tttgcatgtg tgcgaaagta tactcaagcc caatcgccat
      121 ttcggaaaat cggtactgta gagccatctt cacggattcc gtcgatatcc atcttgtcag
      181 atcctaccat gaaatctacg tgggtttgac ttctattcaa tccagcttct gctaattctt
      241 catcggacat ttctgtaccg cctttcacac tgaaggcata agcagaacct agtgctaagt
      301 gattcgatgc gttttcatca aataatgtat tgaaaaagat gatgccagat tgagaaatag
      361 gtgaagggtc aggtacaagt gcgacttctc ctaaacgacg cgcaccttca tctgtatcaa
      421 gcagttttgc taagacatct tctccttgtt cggcagaaaa atcaacaact tttccatctt
      481 taaaagtaaa tttcataccc gagatgatgg tgccagcata actcagtggc tttgtacttg
      541 aaatgtaacc atctactcga tgactgtcag gtgctgtgaa cacttcttcc gtcggcatat
      601 ttgccatgaa tttttctcca cgagcattat agcttccagc gccttcccaa agatggtttt
      661 taggcaatcc gataatgata tctgtaccgg gagcagtata gtgaagggca gaaaattgtt
      721 ctcgattcaa ttcttctgct ttttttgcta atttttcatc atgcttcttc catgctaaga
      781 cagggtcttc ttcatagaca cgagtcgttt tgaaaatctg atcccataat gcctcaactt
      841 gtttttcttc tggcagttct gggaagactt ttgctgccca ttgtttacca gccgcagcca
      901 cgacagtcca actgacttta tttgcttgag ttgccttgcg taaattcatt agtgctttgc
      961 cattcgctga ttgataagac gctactcgat ggctatctac accagcaaat gcatcgggat
     1021 cggcagaaac aacgctgatc ctgcttgctc ctttttcaag ccattcatcc gcttgatcga
     1081 ttttagattg tggtacattc tcaatacgat ccgttgcagc atgtaaaaga aattctcttt
     1141 ggatctggtc gtcagtccat tgaacgataa cctcagcggc tcctagttta taagcttctt
     1201 gtgtgatcaa tcgagcaagg ggtgcctgtt ccacgctgat ctgtaaaaca actgtgtgtc
     1261 ctttttctgt ggctacgcca gtttctgcaa ttaagcgtgc atattttttt agaagttcat
     1321 taaaatcaga taacataata aaaattcctc ctcaccattt tttctggtaa ctattagcat
     1381 gataccattt aattatgatt caaacaatga ggctttaaat aaaaaaagga ggttattttt
     1441 ttaaggttaa gtttcatgat atatgttact acttgctatt tcagcttgtg aagaaaatca
     1501 aaaactaatt ttgcatatca aaaaaaacat gttacaatga aattaatcaa tggtggaagc
     1561 gttataaaaa aattaaggag attaaaaaat atggcaagaa aaaagacgat tactagagaa
     1621 cagattttgg cagctgctta tgaagtagct gccaccgatg gatttacacg atttactgcg
     1681 agaaacatcg cgaacaaaat gaattgttcc acgcaaccga tttatcttga gtttaaaaat
     1741 atggatgact tgagacaagc tctttttgag cagatctatg atcatttaca atatgaagtg
     1801 ttcactgttg agcatacagg gaatacgatt atcgatcttg cttttaatta tatccatttt
     1861 gcaagaagag agaagaagtt gtatcgttca ctgtacttag aagaatatgg tggaggaaaa
     1921 gagatgcaga atttctctta tacttacttt gtgaatacag tgaaacgcga tccagcttat
     1981 gtgaatcttt cagaagagca gatcgaatct ttgtataatg ggacatggat catagctact
     2041 gggatcgcag ctttgatgtc ttcaagcatc atccatccaa ctgatgaaca gattgaaaag
     2101 atgatccaag acagtataga tgctatcttg aaattcaaag aaccaatcga aatcgattga
     2161 atatactcaa aagttccaca aatcagtagg taacaagaga tgtgtcaaaa taaggaaaag
     2221 ttcgtttttc ttacagcgta tgcattttta actcccgaag aactcttcca tgaatgcaat
     2281 gaataaaaga gccatacaga ttgaataaat ctggatggct cttttattgc aagtatatta
     2341 aatttttgcg actagttctt tagcgaaagc ttctaaattt tcgatatctt cttcttcagc
     2401 attcagatcc actttaacat tttcggctcc ttttgatgcg cctgtttttg caaaagcagc
     2461 atcgaaatca tccaccgatt tgcagaattc atcgtaaaaa gtatcaccag atccgcagac
     2521 accgtaaatt tttcccaata gatccaattc ttgcaagtct tcataaaagt ctacgatctc
     2581 atcaggcaga tcgccatcat cgtatgtata agtagctact acgcaaatat ctgcctcctc
     2641 gaattcatct gcatctactt gggtacattc gttgatttcg acttcgatat ccagattttc
     2701 aaatgcttct gcaacaatat cggcgatttc ttcagtgttt cctgtcatgc tagcatatac
     2761 gatttttgct aaagccatga tgtgcctcct cgtttataat tatttaacaa ttatgaatta
     2821 taccaaaaca tcattgaaaa gaaaataaaa cctagagaca cctggggaat gtcatttggc
     2881 taaatgtatg ccgctatgtt aaaatgagag ggatttgtaa aaaggagacg aaaatatgat
     2941 tactttaaaa tcagcacgtg aaattgaaat gatggcagaa tctggagctt tattagcaga
     3001 tgtacataaa aatctgcgtg attttataaa accaggaatc acaagttggg atattgaggt
     3061 atttgtcaga aactatatcg agagtcatgg cggaattgct gcgcaaattg gctttgaagg
     3121 gtatgaatat gcgacttgta tcagtataaa tgatgaaatt tgtcatggat tccctcgtaa
     3181 aaagcctttg aaaaacggtg atttggtaaa agtcgatatg tgtatcgatt tgaaaggcgg
     3241 catttctgat tcttgttggg cctatgtagt tggagaatct acacctgaga tcgaccgatt
     3301 gatggaagta acgaagaaag ctttgtacat cggtattgag caagcacaag tagggaatcg
     3361 gattggtgac atcggtcatg ctatccaaac ttatgtagaa ggcgaaaatc tagcgatcgt
     3421 tcgtgatttt attggtcatg gcgttggtcc tacgattcat gaagaaccag cagttcctca
     3481 ttacggagaa gctggaaaag ggttgcggtt gaaagaaggc atggttatca cgatcgaacc
     3541 tatggttaat accggaactt ggaaaatgaa aatggatcct aacggctgga ctgcgtatac
     3601 aagagacggc ggactttctt gccaatatga acatacattg gctattacta aagatggtcc
     3661 aagaattttg acatcacaag gagaagaagg cacttattga tctatccagt caataggtac
     3721 gggagaggta catgaaagtt tggaacaaaa taaaacaaaa tgaaaatctg atgcgcttta
     3781 ttgagacgac tcaaaagcgc atcactgatt cagaaatgag tacgacctct gtcgtcgttg
     3841 cttattattt actcttgtct ttatttccat tgattattgc ttttggtaat attttaccgt
     3901 ttctccacat cgatcaagag actgtactga cctatttacg agaagtgatt cctgagaccg
     3961 tttaccagtt tatcggtcct gcaatcaaag accttttgac acaaagttca ggaggcttgt
     4021 tatccgtttc tgcattagcg gctttatggt ctgcaagtca aagtatcaat gctttgcaaa
     4081 ttgcgatgaa taaagcgtat ggcgtagaaa atagaaaaaa ttttttgatc gtccgtttct
     4141 tctcactaat tgtcattgtc ttgttcatga ttgctattag tggggtaact atcgttcttg
     4201 ggttgggaca gctgattttg gatgctattc agccaatcgt acaaataccc gtgaacttta
     4261 tcgatcagtt ccaaactttg aagtggccaa tcacattggt agctttattt gtcatcatgt
     4321 tcttgattta tttaattgtc cctaatgctc agttgaagtt gaagacgatc attccgggca
     4381 cgatcttcgc tactgtcggc tggatgctgt tatcacaagt gtttagtatc tatgctaggt
     4441 attttgcaac gaggatcagc ggttatcaga tcataggaag ttttattgta ctcatgcttt
     4501 ggcttaattt tgctgctacg atcatcattt tgggcggaat catcaatgca gttgttcaag
     4561 aatacgtgac gggtcatcaa atcaaaaaac gtcgagatcc aagccgaaaa tggttcaata
     4621 aattgaaaac taaattttct cataaaaaaa agtagaaaca agagttctta ttgtaaattt
     4681 atatcagtaa tttataataa ttatgactct taattaaagt aggtgcccat atgcttgttt
     4741 cttttagtat ggttataaga ttttttctga caattttatt atcactgata ttaacacctg
     4801 tattcaaaat catttcagta caaacaggta tggtcgacaa accaaatgaa agaagaataa
     4861 ataaagttcc aatgccttca gcgggcggac tgcctatctt tatttcattt gttatatcga
     4921 ctttattctt attccgtaaa attatccctc aatcgtatat tgtaccgatc ttgattgctt
     4981 ctttagtaat catagtcaca ggagtgctcg atgataaata tgagctgaca cctaaacaaa
     5041 aaagtatagg gatcttgatt gcttctctta ttatttattt tgtagcagat atacgtattg
     5101 attccttcac gcttcctttt attggatata tccaactagg ctggcttagt tttcccgtaa
     5161 cgattttttg gatcttcggt atcacgaatg cggtcaatct gattgacggt ttggatgggc
     5221 tggcggcagg gatttcattg atcggtttaa ttacgatagg aatcattgga tattttttcc
     5281 tccatgcttc tacagtgtat attccagttg ttattttctg tcttgtagca agtattatcg
     5341 gtttttttcc ttacaatttt tatccggcaa agatttattt aggcgataca ggagctctat
     5401 tcctagggtt tatgatggcc gtcctttcac tacaagggct gaagaacgtg acttttgttt
     5461 catcgatttc tttgctgatc gtcatgggag tgccggtaac agacacgttt tttgctatca
     5521 ttaggagaaa agcaaaccgt gtttcttttt ctacagcaga taaaaaacat cttcatcacc
     5581 gactaatcag tttaggcttt actcataaag gtgctgtcct gacgatttat gcgatggctt
     5641 tgatgttttc tttcacagct atggtcatga attatactgg aagaatcgga acgatcatat
     5701 tgattattgc catgttgttt gctgcaattt tattatttga attgattggt ctgatcaatg
     5761 agaaacatca gtttatttta aaaacattgc gatttttagg gaataaagag taccgtacgc
     5821 aagtaaaaca gaaatatttg aagaaatgga accgtcatat agatgaataa caaattaaac
     5881 cagccgatcc ttattagtat tgtgacggca aacagtgata aaatttttcg gacactagat
     5941 aattttattt caactgtaaa agatgaaaca gcagtaaaaa tccgaatttt tgacaacaat
     6001 tcacttcccg agtacaaaaa aagactaaca gagtatagga aatatcccta catcgatatc
     6061 tattttcatg atgaaaattc cggatttggt tatggacata atcacaatct gatagctagc
     6121 gattctcgct atggcattat ttgtaaccca gatattttag tggatgaaga gacagttaca
     6181 gcattggtct tgttattgaa agaacatccg gaatgtgcga tgttagcacc taagattctt
     6241 aatgaagatg gaacaactca gcacctcatc cgtgagcagc tggctgtttt tgattacgtt
     6301 ttgcgctttg tgcctttcaa atgggtcaaa aaaaagtttg acaaacgact ggctgtgttt
     6361 gaatgccgag gattgcctac tgatgctaat agttatgtac ggatgatctc aggtagtttt
     6421 atggtagctg atattgataa atttaaagag ataaaggggt ttgatgagcg tttcttcatg
     6481 tactttgaag acaacgactt gtgtttgagt tttgaaaaag caggttacaa gttattgtac
     6541 acaccctttt atgcagttat ccatttttac gggaagggtg cgcatcgaaa tgcaaaactg
     6601 tttcgcgtgt ttttgacttc tatgatgaaa tttttcaata agtgggggtg gcgttttttc
     6661 tgatgaaacc agaaatatta gtagtcgttg tgctttatca gcaactattc agtcaatctc
     6721 cagcttatgg accattaagc aaagcactta gcgaaaagca aattcagctt attatttacg
     6781 ataatagtcc tcaaaggcag caaaatgagc tgtttgaaaa agaaaatatc gtttatcatc
     6841 atgatccgca aaatcctggt ttagcggtgg cttataattt tgcgttgtct caagcagatg
     6901 aaggaacacg ttgtctcgtc actctggatc aggatacgag gctagtcgac gattattttg
     6961 aactattgcg taaagtaacc tttacagatg aatgtgttgc tgcagttccg atgatttttt
     7021 ctgggagccg acaagtttct cccctatatt cagatcgtta tatcaatcgt acagctcaag
     7081 cagtagaagt tgaaggccca acagctgaac gaatcatggc aatcaattca ggtgttgcct
     7141 ggtctgtcaa atttctaaaa aagattggcg ggtttaatcc tgctttttct ttagattttt
     7201 tggatcattg gctgttttgg aaagtggatc agttggaaaa aactgtggag atccttcctg
     7261 tacgaatgga acatgatctt tcggttttag actatgaaaa agtttcaagt aatcgatacc
     7321 gttctatttt acaagcagaa aatcgatttt atcatgaata tgatcaaagg catttatcca
     7381 gtcaccgacg acaattattg ttaagaacag ctaaacagtt cttgaccgtc aaaaaccggc
     7441 atatctggcg gatgactttg cgctcatatg ttaagaattg gaaggtgtga attcgtgcgt
     7501 tcggtttgta tagctacctt taatggaggc agatatttaa gagagcagtt agatagtatt
     7561 ttatctcagc tttcagcaga agatgaagta gtcatttctg atgatgggtc agtagatgat
     7621 acatgggata tattaactga atacgcagaa aaagataagc gaatccagct tttttcgggg
     7681 cctcgtcaag gattgatcgc taattttggt tatgcgatcc agcagacgaa aggagatcta
     7741 atctttttgg cagaccaaga tgatgtttgg ttggagacaa aagtgaaaaa gatcactgac
     7801 tattttgagc agaatccgga tcagctagta gtagtttctg atttaatcat tgtggacagc
     7861 gagctgcaag agatccatga ttcgtatttt tcgtttcgaa attccaaaga aggatggctt
     7921 aataatgtga taagaagtca ctatattggt gctggtatgg ctttccggtc ttctttaaaa
     7981 cccgatattt tgccgatccc gtcagaagtg ccgatgcatg atatgtggat tggtttgctg
     8041 ggaggaaaga agactgggtt cctaagagaa ccgttaactc tgtaccgaag acatgattta
     8101 aacgcgagtg agattgaaac acattctaaa ttacggcaaa aaatttcttg gcgtgttcat
     8161 ctgattacgg cgttgatcaa acgaaaatgg tttaaacgtt gataaaagat gtttaaatcc
     8221 ttaatatttc catgacaaat ataacaattg atgagataat aacaaagtga aatttgaaat
     8281 caaaaaggag agcagatatc catgaaggga atcattcttg ctgggggcag cggaacacgt
     8341 ctgtaccctt taacaaaggc aacatcgaaa caattgatgc cgatttatga caaaccaatg
     8401 atttattatc caatgtctac tctgatgttg gcgggaatca aagaaattct gattatttca
     8461 acgccacaag atacaccacg tttcaaggaa ttatttggaa acggaaatga tttaggactg
     8521 cagatcgaat atgcagtaca agaaagtcca gatggattgg cacaagcgtt tatcattgga
     8581 gaagaattta ttggagatga tagtgtctgc ttggtattag gggacaatat ttactatggt
     8641 ggcggtctgt ctaaaatgtt gcaacgagca gcttcaaaag atacaggcgc gacagtattt
     8701 ggctatcatg tcaatgatcc agaacgcttt ggtgtagtag aatttgatga gaatatgcaa
     8761 gctttgtcga ttgaagaaaa gcctgctcag ccaaaatcaa attacgctgt aactggcctt
     8821 tatttttatg acaatgaggt aatttctatc gctaaaggta tcaaaccttc agaacgtgga
     8881 gaactagaga ttacggatgt caataaagca tatttggata aaggaaaact atccgtagaa
     8941 cttatgggac gcggatttgc ttggcttgat acaggaacac atgaatcatt gcttgaagca
     9001 tctaccttta tcgaaacaat tgaaaaacgt cagaacttaa aagtggcttg tttggaagaa
     9061 attgcttacc gtatgggcta catcgataag gaacaattgc tggcccttgc acagccattg
     9121 aaaaaaaatc aatacggtca atatttattg aatttggccg ctgaataagg agtccttaca
     9181 gatgaaagta acagatacaa aattaacaga tgtcaaaatc gtagaaatgg acgtctttgg
     9241 cgatcatcgc ggtttcttca cagaaagtta ttcaaaagca aaatttgcag aacatggatt
     9301 gaaatatgac tttgttcaag acaaccattc actatcagct gaagctggtg tccttcgggg
     9361 gcttcatttc caaaaaggag aagctgcaca gacaaaattg attcgggtag tcactggagc
     9421 agttttagat gtagtagtgg atatccgcaa aggtagcccg acttatggtc aatgggacgg
     9481 atttatctta tctgaacata atcatcgaca gttgcttgta cctaaaggat atgcccatgg
     9541 attcgttact ttgacaccaa atgtgaactt cctttataag tgtgataatt actataatgc
     9601 agaagcagat gggggcatcg catttgatga tccagattta gcgattgatt ggccaattga
     9661 tccatcaaga gcgattatgt cggaaaaaga tcaccgtcat ccgacattaa aagaatttga
     9721 agcagaaaat ccatttgttt acggagaaat ctaagaatta aggagaaatt ttcttatgaa
     9781 aaacatcatt gttaccggag gtgccggatt catcggctct aatttcgttc attacgtggt
     9841 aaacaatcat ccagaagtgc atgtcactgt tttggataaa ctgacttatg caggaaacaa
     9901 agagaacttg gctggacttc ctagcgatcg cgtagaattg gtcgtaggag atgttgcaga
     9961 tgcagaatta gtggaccgtc tagtaaaaga agcggacgca gttgttcatt acgcggcaga
    10021 atcccataac gataattcat taaaagatcc tttcccattt gtacaaacga atatcattgg
    10081 tacgtataca cttttagaag cttgccgcaa gtatgatgta cgctatcatc acgtatctac
    10141 tgacgaggtt tacggcgatc ttccattacg tgaagacctg ccaggacatg gggaaggcga
    10201 aggagaaaaa ttcactgcgg aaacaccata taatccttca agtccatatt cttctacaaa
    10261 agctggttca gatctgttag taaaagcatg ggtgcgttct tttggcttac gtgcaaccat
    10321 ttcaaactgt tcaaacaact atggtcctta tcagcatatt gaaaaattta ttcctcgcca
    10381 agtaacgaat atcttaagcg gtattcgtcc aaaattatat ggcgaaggaa agaatgttcg
    10441 tgactggatc catacgaatg atcattcttc agcagtgtgg ctgattttga cgaaaggcag
    10501 aattggcgaa acctatctga tcggtgcaga cggtgaagaa gataataaga ccgtgatgga
    10561 attgatctta gaaatgatgg gtcaaccaaa agatgcgtac gaccatgtaa acgaccgtgc
    10621 aggacacgac ttgcgttatg caatcgattc gacaaaatta cgggaagagt taggatggaa
    10681 gcctgagttt acgaacttcc gtgatgggtt ggctgacacg atcaaatggt acgaagaaca
    10741 tgaagactgg tggaaaaaag aaaaagaggc cgttgaagca gcatatgcca aaaatggaca
    10801 ataatacaga gaaaatgtca ctgtattaat ggaaaaacac atgtgaggca ggcgctcgcc
    10861 tgtctctttt ttaaaataaa aatcaaggag cggataatca tatgttttta ttaactggag
    10921 gaaatgggca actaggtaca gaattgcgcc atttattaga tgaaaaaaat ctgcaatatg
    10981 tttcaacaga tgcaaaagac ttggatatca cagatgccga gaaaacaatg gcttacatca
    11041 cagaattaaa acctgatgtt attttccatt gtgcagctta cacagcagta gataaagcag
    11101 aagaagaagc aaaagaatta gatgagaaga tcaatgttga tggtacaaga aatgtagcac
    11161 ttgcagcaaa agctgtgaat gctcaattcg tctatatcag tacagactat gttttcgatg
    11221 gaaaaaacaa aaatgtagaa tacgaagtag acgaccaaac gaatccacta aatgaatatg
    11281 gtcgtacgaa attattaggc gaaaaagcag tagaagagat tttagaagac tattatatca
    11341 tacgaacttc ttgggttttc gggatctatg gacacaattt cgtcttcacg atgcaacgcc
    11401 tagcggaaac ccgcgacaaa ctgactgtag taaatgacca gtttgggcga ccaacttgga
    11461 cacgtacttt ggcagaattt atggtatatg tcatcgaaga aaaagcacca tttggtattt
    11521 atcatttgtc gaacgaaaat agctgttctt ggtatgaatt cgcaaaagaa atattgaaag
    11581 atacagatgt agaagttgca cctgttacgt cagaagaatt tccgcaaaaa gcaacacgtc
    11641 cgcagtattc agtcatgagc ctgaaaaaga cagaagagtt aggatttgtc ataccaactt
    11701 ggcaagaagc acttgcgcaa atgctggaag ctgccaaaaa aatgaataag taatttcctt
    11761 ttatcaaata gaatttggag catgatatgg aaaaacaaac aagaagtgca cgacgaaaag
    11821 aaaagccaaa agcgaaccag gcagattcga atttggtgct tgacctgttt ctaaaactcc
    11881 gctatcttat tggcgtttta gtcatcgtgg tcatcgttac ttttaattta aacggaagtt
    11941 cacttggtgt ttgggataaa tatgtgtcgc aaagagacga tgggaaaaaa actgatgtga
    12001 tttttggaca gaatcgggaa gtgcggtcag acgaatggct ggtgcagaca cctttttacc
    12061 tctcacaagc tgaagaggac tttccgttgg tgaacgagga ttattcatta aacggacaaa
    12121 acatgatcat tgcgtataat tctcctgtaa aggatattac ggttatcgga aaaccattca
    12181 actggggatt ctttttcctc ggaagagatc gaggactttc cttttattgg gcgatgaaat
    12241 tagtcgtcat ggtcttgctt ggattcgaag tactgatgat attaacgaag agaaaaaaag
    12301 ctctatcgct aatcggtgca tttgcgctga cattttctcc agcagtccag tggtggttca
    12361 tgcaacatgt gggcgatttg attttcttta ctttgggact gatgactgct ttttatcatt
    12421 atttctacaa tcatgataaa aaatggctac gaacgttgat gatgcttttg gtggttattt
    12481 tcggtattgg gtttatttta gtgatttacc cagcccatca agtgatgctg gcgtacttgc
    12541 tgatttttta ttttgttggc ctgcttattt actatagcaa gaaagtttca tgggatctgt
    12601 tggatgtagt gttgattgga ggggcagttt tatttattgg cggagtcatg gttcatttct
    12661 ggctaacgtc aaaagacgca ttgttagctt ctttgaatac cttatatcca ggaaaacggg
    12721 taagtactgg aggaaagtgg acgattggcg aatttttttc tttccttaca aattggaaaa
    12781 ttccttttga agatatcaac tattcgaata actctgaagt ggccctgttc tatcactttt
    12841 ttccaactgt attcctagca agtccatttg tgttatttgg caaaaaagat agcgaacaaa
    12901 agttactggg acgtattttg atgatttttt gtctgttttc tatcttttgg attaccgttg
    12961 ggttgccaaa atggctagca gaaatcactc tgctgtctta tgttcctcca ttaagagcca
    13021 tccttacttt tagttttgcg gcttgtttat tatcgatctg gtttatcgct tatatttgga
    13081 gagaagatgt tattcctatt tggtataaat tcattttgtt ggcagtaaat gcatggtctt
    13141 atttctatgc gattacgcat tcgaaaatgg ataattattt ttcggatttt gaaaccatcg
    13201 cagttgctgt gttgggaaca gtgattttag cttttgcatt atttggctgg agacgcttgt
    13261 tttacctcgc ttttgccgcc ttagttatcg tatctggctt tttcgtcaat ccagtcgtag
    13321 aaggtacagg agcgattttt gaaaaaacac tggcaaaaga aatccaaaaa atcgatcaac
    13381 aagatcctgg taaagtttgg ttgtctgaag atgaattata taacttcacc ccaacattgg
    13441 gagtgaaatc cttcaataca gtacgctttt atccagatat agctgcatgg aagaaaatcg
    13501 atccgaaaga agaatacgag aagtattata atcggtatgc tcatacaaga gcttttatcg
    13561 ctaaggaaga tacaaagttc attttagatc gtccagatat gttttcggtc acgttgaatt
    13621 ttgaagacgc agaaaaatta gggatcgact atgtgatcag taaacgacca ttaactgatt
    13681 acaaccaatt atatgaagcg cagttcacgc agctatatgg accggataaa gacggttata
    13741 tgatttttaa agtagaatat ccggattatc cagatgtacc acaaacacaa actcaggaaa
    13801 atcagctagt cgtacagtaa taggctagct gagaataatc ctgaaatgtt agtagaaagg
    13861 agagtggaga taattcaagc aatcgtacaa aaatttgtca acaaaatgag tgtcggtttc
    13921 ttgcttttgt tactgacgct agtctttttt gtttggacag cagggttagg ttttccagca
    13981 actttgttta tatataacaa tagttcatta cttatcgctt ttagtgtggc tattttgctc
    14041 attttaaatg tttataaagc aaaaggcgtc gattttcttt atctaggtgt tgcgcttgcc
    14101 cttttcattt tcttttctta ctttcgggaa ttaagaaatg agtctttatt tggagactta
    14161 ctgtttcctt tgattatttt attttgttta gtaattaaat ggatcgagtg gacaaaatgg
    14221 gatcgcggta tttatctgat tgtcttttcg gtcttcctcg gaatcacgtt tatcgtgtat
    14281 ttacagagat ccaagtacca gaaggacaaa gcatctgggc tccaggcaat tcgctttctg
    14341 atatttggat caatacgaat acaatcggaa gttctttgat gactcttgct ttattgatca
    14401 gtggatttgc cagttctttt gaacgatggt atgtacgaat catcggtgca gtagcagttg
    14461 ttgcagcttt tctcgggatt tgggtctgcc aatctagagg tgcattagtc gcgttgattg
    14521 tttttgcgat attggatctt ttacctaaat cgttgatgcg tgtcattcgt gcgccattta
    14581 ttgcttacac ggttacgatt cttttagctt tgccgatttc ttatctggcg gctgtctctg
    14641 aaaaagtcaa tttgtttacc ggtcgagaag atatttggca taaattctat cagacgctag
    14701 gagaaaaatc tgaacaaatt ttactaggaa tgaaaacatt tatcttccaa cgaggaaacc
    14761 aatttttagg aaaccacaat agttataatt ctattttgaa tatctatgga ttgataggat
    14821 ttgggattgc tgctttgctg cttatccttt ttattggtcg cttaacgttg aaagcagatt
    14881 tatccaacgg gcagatgact tttatctggg ccttttttgc ggtgatgatg cagtcattta
    14941 tggaggatac attgacttca taaccatggg ttccgattat ttatatcctg ttggctatgg
    15001 ccgttcatcg atatgatgaa ccagaagttg cggaggaatt ctatgttatg gaagaggcat
    15061 atgacgatat gacttatgat gatacatctt atgaggaaca accagatagc gctcattctt
    15121 ccaggatcca acgctatcat tgataggcac aaaatacgag agaggctgtg acaaccgtcg
    15181 cagccttttt tggtttattg caattgtcta gcatcttctg taaaatagaa acgttagaga
    15241 aaatcttgta tcatagaaaa ttaagaaaga aataagaacg cagctcggta ccaaaaatat
    15301 ggtaaaatgg cacttgactg taattcactg aaaatcgctt ggaggaacac aaatgtttaa
    15361 agatttgtat ttatttatga aggacattta tcagaacaga aaattattgc tacagttttc
    15421 gatcaatgac ttcaaatcaa gatatgcagg atcgttttta ggaatcttat gggcgtttat
    15481 caatccgcta tttactgtat tgatttattg gctggtattt ggtgttggac tgaaagcaca
    15541 aatgatcgat gcaaaatacc catttatcgt atatttagtt accgggatga ttccctggtt
    15601 cttcttctca gatgcatttg catcaactac ggttgttttt cgggaatata cttatttagt
    15661 aaagaaagtc gtattcaata ttcgtatctt gcccacgacg aaaatcctat ccaatctgta
    15721 cacccattta ttcttcattc tgattggcat agctgtcgcg cttataaatg gtatatatcc
    15781 ttcagcaatg tctttacagc tgatttatta tttattttgc atgtgtgctt tcttgacagg
    15841 attgacttgg ctgacggcat cgatccaacc atttttacct gatatcatgc aattaattac
    15901 gatcgtgctg cagttgatca tgtggacatt accgatatta tggagcccta atcagtttga
    15961 ttcaggtctt gtaagcatat tgaaattaaa tccgctgtac tatgttgttc aaggttatcg
    16021 tgagtcattt ttaagtgaag cttggttctg ggagcatgga acatatactt tgtatttctg
    16081 ggttttcacg ttagtaatgt tcgtaatcgg ctctgcagtg ttccgtagat tgaaaccaca
    16141 tttttcagat gtgctgtaag gagaatagct atgacagaat atgcaattag actaaaagat
    16201 atcacaaaat cttataatat gtacgcaaaa ccttcggatc gatttcgtga agccctcaat
    16261 ccttttaaga aatcctatca tgatgtattt tatgcgttga aaaacgtgaa tgtagaaata
    16321 aaaaaaggtg agatgatcgg tttcgtggga gaaaacggat cgggaaaatc tacaatgttg
    16381 aaaatcatta cgggagtact gacaccaaca tccggcacga tggaaatcga aggaaaaatc
    16441 tcagctttgc tagaactagg atcaggattc aatcctgagt attctggcta tgaaaatatc
    16501 tatttaaatg gaatggttct aggattttca agagaagaag tcgatgaaat ggtcgatgat
    16561 atcattgaat ttgctgacat cggagaccat atttatcaac ctgtaaaaac ttattcaagc
    16621 gggatgttcg ttcgtctagc ttttgctgta gcaatcaatg tgaatcccga tattttgatt
    16681 gtggatgaag cattggcagt aggcgatctt gaatttcaac taaaatgtat ggaaaaattt
    16741 acagaaatca agaactcggg aaagacgatt ttattcgttt ctcatgatat cagttcgatt
    16801 cgtcgttttt gtgatcgttc ctattggttg aaaaacggag aagtcgtcga atatggcgat
    16861 acgatggaag taacgacgaa ttatgaaaac tttttaaaga aaaaatcagt taaaacagtg
    16921 gatcggaata aaaaccaagt agaacggttc gccgctccag atatcgtcga cgtgacgaaa
    16981 gcggaattgt tggataaaga caaaaatccg gtggatatgc tggaacaagg agaaaaacta
    17041 tacgttaaag taacttatga agtaaaagat gatacaatca aaaatccggt tttaggaatt
    17101 gcgctacgaa cagtcgacaa tttttatgta tgcggactta atactctact agatggtatc
    17161 aagattcctt ggaaaaaagg agagaatatc ttttatctgg agtatgaaaa gttaggtttg
    17221 ttagctggtg aatattattt tgacgttgcg gtctttgaag aaaatgcaac ggttcctttg
    17281 gtatataaga caaagtacat gaacttgttt gtcagcggtt cttatatcgg agaaggcatc
    17341 gtggtcttag accataaatg ggaagaaggg actcatagca atgaaatatg attttgaaat
    17401 ggacctagat gaacaaagca gtgtgggaaa aattgccgca cagatcaaac caggaagtaa
    17461 agttttagag tttggtcccg gaaacggccg attaacgaaa catttaatcg gagcaaaaca
    17521 atgtgaagtg agcattgttg agttagataa ggaattgttc gattttgtca gcgaatttgc
    17581 tcaagatgga ttttatggtg atatcgaaag ttttgagtgg gcaaactatt atgctggaca
    17641 gacatttgat tacgtcttgt ttgcggatgt tttagaacat ttggtagatc ctggaaaaac
    17701 attgaagaaa gtcagagaat ttttgaatga agaaggagag atcctgatta cattccctaa
    17761 cttggcgcat aattctgtca tgatcgattt gttcaataac caattgccgt gggcttctta
    17821 tggtctccta gatgaaaccc ataattcttt ttatactcat gatggcttcc aaaaagtttt
    17881 tgaaaaagcg ggattattca ttaatattga agattatttg tacttagctg taggtgatac
    17941 agaattaaaa tcaacttatg aagaattgcc ggaagctgta cgctatgatt tcaaaatgcg
    18001 accatttggt gaagtctacc aatacttttt ctcattgatg aaacatccag tagcacaaag
    18061 ttccattgca gagccacaaa attctaatta tgtaaaagtg ttagaagtaa cccagcaaac
    18121 gaaacaagat gaaacaatcc aacaaatacc attcaataat ttcacagggg aaaatgagac
    18181 actaagtttc cccgtatcag aaacaacaga aagaatggtg tttcgcttcg cgcaacaacc
    18241 tagctttatc gaattcagcg cagaagctgc cggagaaaaa ctaacattta tcgattcgaa
    18301 tgctgtagtc aaaacagtaa atgattgtta tttgtttgat gggaaagaat taccagagtt
    18361 cgttctaacg gatatttctg ggaaagaagt gactatccat tgtcactatc gctttatcgg
    18421 ggaattgaca ccaacaatga aagaattgtt ggaaacgatt cgtcccatgg ctgaagtcac
    18481 aaagcagctt tctgagaaaa atgacgaatt agaaagagaa aatcatcatc ttcttgagga
    18541 aaatacaaga ctagaccata cgttaaaaac aaccacaaat cgctattgca cattgttgga
    18601 aagtgatgaa tggacaataa aacatagact aggacgacgt aagaaagaaa cttcgaaaaa
    18661 aatccaagaa aaagaacttt ctatatgtat tgacgagaaa atctgggatg cagaaacaaa
    18721 aatattaaaa atcatcggat ggggaatcgc taattcggat cgccagccct tgtcctataa
    18781 gttatcagct gaccaatcgc catttttcga agcaattcct gtttcacgag aagaagtcaa
    18841 tcaagcagaa cagctcgcaa aaggaacaga agcgggattt gagttacgaa tcctttgcga
    18901 gcaagaacgt tcattcttag tggaagcagt agctcaaaat ggccaatcat ggatcattga
    18961 aatgtaaata atgattaact tataaagata aggagtaaac gaatcgtgca aaaaaaagaa
    19021 attgccgtat ttatcgatca aatcactcgt gaacgggcca ctggcgattt gcttattgtg
    19081 ggctgggcaa ttgatgaagt gaccaaagaa atccctacga taaaggtaga aaaagaaaat
    19141 gtgattgctg aagcaacaca tgtcgtaaga ttggatatca atcatttata taatcttgat
    19201 gttaagaccc aaagcggttt taaggtacgt ttatcaggga aaatgagagg aaaagccatc
    19261 ttagacttcc aaacagcgag acatcaaaat ggcatagctg tgaaattaaa cggtaaatac
    19321 ccttatgatg acggcattga atcttcatgg gaaagaaaaa aaagattact gaaaaaaggg
    19381 ataaattatg caaggactca tggcgtaaaa aaagcgatcc gtcgggtcaa attggaattg
    19441 aagccaggat cgatcgacta tgcagagtgg atcagtcgtc atgagaaacc agatttgaaa
    19501 gagcaaagga aagaagcaca aggatttgcg taccgtccat tgatttccat acttatgcct
    19561 gtctataacg ttgaaatcaa atggctcgaa aaatgcattg attcggtact ggatcaaacg
    19621 tatgatcatt gggaactatg tatcagtgat gatgcttcta ctgatccagc tatccgaaag
    19681 tgtctggaat cctatcaagc aaaagatgat agaatcaaag tcgttttccg aaaagaaaat
    19741 ggacacatca gtctggcaac taattctgca ttggaaatag cagaaggaga atttatagca
    19801 ctcttagata atgatgatga attaccgcca tttgcattat atgaagtggc aaaagtgcta
    19861 aacgtacatc cagaactgga tgtgatctac agtgacgaag ataaaatcga tgcagatggc
    19921 aatcgctttg atccgcattt caaagcagac tggtcgcctg atacattgat gggaaataat
    19981 tatatctctc acttaggcgt atatcgaaca agcattgtta aagaacttgg cggtttccgt
    20041 aaaggctatg aaggttctca agattatgat ttggtccttc gtgtgacaga acaaatccct
    20101 gcagatcata tttaccacat tgaccgagtc ttgtatcatt ggcggacgat cccaggatca
    20161 actgcaagta atggcgaagc caaaagttat atctatgatt ccggagtgaa agcattgaca
    20221 gatgccctgt ctagaagaaa catcaaagga agcgtacgtc ctggcagaat ttctggattt
    20281 tatgagattg cttatgacgt cttgcaagag gatttggtca gtgtgatcat tccaacgaag
    20341 aatggctatg aagatctaaa aacttgtgtg gattcgatca tcgaaaaaac gtcttattca
    20401 aattatgaaa tcattattgc ggataacgga agtacagatc caaaaatgca agaattattt
    20461 gcagaataca agcatcagct gaaagaccgc tttatcgtag aattgattga cattccattc
    20521 aattattctc gaattaacaa tttagcagca gaaaaagcaa acggcaaata ctttttattc
    20581 ttgaataacg atacagaagt gattgagcca gattggatga cggtgatggt ttcttatgca
    20641 cagtttgatc gaatcggctg tgtaggagca aaactgtttt atccagatga tacaacgcag
    20701 catgcaggag tattattagg aatcggtggt gttgcagggc atgcattgaa taactatgat
    20761 cgaacacatt gtggttattt cggccgattg gtcattgacg tcaattactt agcagtcact
    20821 gcagcttgta tgatggtcaa ggcagctgac ttcaatgctg ttaacgggtt tgatgaaaca
    20881 ttagaagtag cattcaacga tgttgacttg tgcttgaaag tttatgaact gggtcgttac
    20941 aatgtctatg cacatcaagc agaattgtac catttcgaat ctaaatcaag aggttatgaa
    21001 gatactccag aaaaacaaag acgttttgct ggtgaaatca aaaaaatgca agataaatgg
    21061 ccagcatata ttgcgcatga tccattttac aatgataatt taacaaaaga aggaatcggc
    21121 gacttttcgt tgagaccaga ttaaactata ataaaaagct gttatgttgt gattcgctcg
    21181 cacataacgg ctttttatag ttttttgtca aaaaaaggca gaaggtgccg actcaaaaaa
    21241 ataagtcgag gttgggacag aagtgtttaa ctccgagaaa taagaagaaa ttcacgaaaa
    21301 ttgcttttca aatttttgtg aatttcggct tatttaagaa gaagttgctt ctgctcccac
    21361 cgtttattcg tttttaaaga atgagacaaa agtgtttctt acttttgtcc cacgctctta
    21421 ttcatgctca gagcgccaat agatacaaaa tcatagccaa agtttcacga accctagctg
    21481 tcaaagaatc gatattttat tttaatatag gctattttaa aataaatggt ttaaggtatt
    21541 cctctacaaa agccactcta tcaattatca tgggtttaaa ataagaagtg atggagataa
    21601 ccagattgtt cttagcgtca atataaagaa catttccact attaccaatt gctgaatata
    21661 tttcgttctc agaatctaat acccaccata aatagccata tctcatattt tgtaagtctt
    21721 ctaaagcact ggttctaggt ttgaacatct cgtttatcca catgggtggt acgatttgtt
    21781 ttcctttata catcccttta tttaggcata atacaccaat ttttgccaga tcacttgccg
    21841 ataaacacaa accatatcct gccgtcccga tatttagtgg atcacaaaac cagacattgg
    21901 ttttaggaga cttatccatt gtaaactgct tatgttcttc agctgtttca gcataataat
    21961 tgacatggtt tggtatccct ataggatcaa atagatactt attggcaaaa tcaacagttg
    22021 ttagcttact tgtctgatac aacaagccag ttaatatgtg taaacagaca gtttgatagt
    22081 tgaattcgcc ggttatacct tttcttcctc ccaataaatc tagtgatgtt tttgtccaat
    22141 cttcacttga acagactttt gtccatggat cgcctttaca tttgtagggt gctttcattg
    22201 ttagcaagtg cttgattgta atagcgtaaa tagttttctc cccgcgtttc actttatact
    22261 ctggaaaata atctaatact ttatcatcga tacttttgat taatccttgc tctaaagcaa
    22321 tgccaatcag caaagataca atacttttcg ttgctgacat gatatgacaa gtatcgtctt
    22381 ttttataacc attccattca tctgtataaa cttctacccc atccttatat gcgacaattt
    22441 gacatatatt tggttgtcga aaaccaataa aatcatgcaa ctcttgttta ttcataagat
    22501 attacctcac tttcttctat aagcataatg tcattaaaaa tcgatttcaa ttttttcgat
    22561 tcttcacgta atacaggtat tcttatggac tagacagcgc tttgggaaga tggattctct
    22621 gaaaaatata aaggttcact ttatgagtgg ataaaaaaag cagcaaatac ttcgacttct
    22681 ttaatttacc aacattagtg aaaatcgatt catctggaga tttgtaattt agagtccttg
    22741 tcttgattag aggtgtataa agctttttat tagacatttt taaattccat tacaatttgc
    22801 ttataaacta ggtttttaaa ggtgactatg gtaagataat agagatatta ttttgtg
//
LOCUS       DAFEKH010000047        21642 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.048, whole genome shotgun sequence.
ACCESSION   DAFEKH010000047
VERSION     DAFEKH010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21642
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.048"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            144..542
                     /locus_tag="LP386_002034"
     CDS             144..542
                     /locus_tag="LP386_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBL1919266.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            526..1221
                     /locus_tag="LP386_002035"
     CDS             526..1221
                     /locus_tag="LP386_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBL1919267.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(1805..2692)
                     /locus_tag="LP386_002036"
     CDS             complement(1805..2692)
                     /locus_tag="LP386_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBL1919268.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2877..3716
                     /locus_tag="LP386_002037"
     CDS             2877..3716
                     /locus_tag="LP386_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBL1919269.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3912..4886
                     /gene="sgrA"
                     /locus_tag="LP386_002038"
     CDS             3912..4886
                     /gene="sgrA"
                     /locus_tag="LP386_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HBL1919270.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5184..5540
                     /locus_tag="LP386_002039"
     CDS             5184..5540
                     /locus_tag="LP386_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919271.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5543..6700
                     /locus_tag="LP386_002040"
     CDS             5543..6700
                     /locus_tag="LP386_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1919272.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6726..7166)
                     /locus_tag="LP386_002041"
     CDS             complement(6726..7166)
                     /locus_tag="LP386_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBL1919273.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7326..7832
                     /locus_tag="LP386_002042"
     CDS             7326..7832
                     /locus_tag="LP386_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBL1919274.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            8000..9913
                     /locus_tag="LP386_002043"
     CDS             8000..9913
                     /locus_tag="LP386_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBL1919275.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            9918..10919
                     /locus_tag="LP386_002044"
     CDS             9918..10919
                     /locus_tag="LP386_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL1919276.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(11121..11327)
                     /locus_tag="LP386_002045"
     CDS             complement(11121..11327)
                     /locus_tag="LP386_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HBL1919277.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11973..12821)
                     /locus_tag="LP386_002046"
     CDS             complement(11973..12821)
                     /locus_tag="LP386_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL1919278.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12820..13887
                     /gene="gnd"
                     /locus_tag="LP386_002047"
     CDS             12820..13887
                     /gene="gnd"
                     /locus_tag="LP386_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HBL1919279.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            13889..14890
                     /locus_tag="LP386_002048"
     CDS             13889..14890
                     /locus_tag="LP386_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HBL1919280.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14887..15171
                     /locus_tag="LP386_002049"
     CDS             14887..15171
                     /locus_tag="LP386_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HBL1919281.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15204..16001
                     /locus_tag="LP386_002050"
     CDS             15204..16001
                     /locus_tag="LP386_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBL1919282.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSSVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            16015..16848
                     /locus_tag="LP386_002051"
     CDS             16015..16848
                     /locus_tag="LP386_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL1919283.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16866..17723
                     /locus_tag="LP386_002052"
     CDS             16866..17723
                     /locus_tag="LP386_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL1919284.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17745..18254
                     /locus_tag="LP386_002053"
     CDS             17745..18254
                     /locus_tag="LP386_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1919285.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18291..18692
                     /locus_tag="LP386_002054"
     CDS             18291..18692
                     /locus_tag="LP386_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919286.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18804..19157
                     /locus_tag="LP386_002055"
     CDS             18804..19157
                     /locus_tag="LP386_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919287.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19191..19634
                     /locus_tag="LP386_002056"
     CDS             19191..19634
                     /locus_tag="LP386_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBL1919288.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19651..20736
                     /gene="uxuA"
                     /locus_tag="LP386_002057"
     CDS             19651..20736
                     /gene="uxuA"
                     /locus_tag="LP386_002057"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBL1919289.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20729..21442
                     /locus_tag="LP386_002058"
     CDS             20729..21442
                     /locus_tag="LP386_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBL1919290.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
BASE COUNT         7457 a         3321 c         4509 g         6355 t
ORIGIN      
        1 tccatacatc cattgtactc tgagaaatca cacaatatcg aaacaaattc cgttaggaat
       61 gtgttattca ataaatttta taatctagaa acattttgaa taaaaactat tagacaaatg
      121 atattttacg aggaggaaca gagatgacga tctttgaaac ggttgtaaca gatgttggta
      181 tagaagcaga agtattcagg aaagaaaaaa taatgatttt atttggagat gaagcaccgg
      241 aaacattaac agattattgt tataagattg aattgaatca ggtaagaaaa gaaataactt
      301 gtgatatgaa gctctgtttt gataaacaaa tgtatgtaat cacagcagta ggagatgttg
      361 tccaaactaa tttgaatgaa ttaggacata tcacgataaa atttgatgga tctcatgagc
      421 cggaacttcc aggaacaatg tatgtagaag ataaggaaat gccgcattta agaaagggga
      481 caatcattaa aatcgatcaa gaggatcaga atgggggaaa gctatatgga aatcatgctt
      541 gatacagcaa atacaaaaag tatttattct tgtcaacagt ttttgaattt aacaggcgta
      601 acaacaaatc ctacaattct gaaaaaagaa ggagcgtcaa acttcttctc gcatatgaaa
      661 gaaatcaaaa aaataatcgg acagattcct atccatattc agacaatagg aagaacggaa
      721 gaagaaatga tagaggatgc tcgagttatc atagaagaac tgggaaaaga tacgtttatc
      781 aaggtgccgg tgaatcaagc aggccttcaa gcgatcaaaa agttgaaaaa agaaggttat
      841 ttgattaccg gtacagctat ttacacagaa ttacaagggt atttagctat taataatgga
      901 gcagattata ttgcacctta ttataacagg atgcaaaatc aaggcattga tgctatgaaa
      961 gtgattgatt cgttgcggac tgagatcgaa cgtacgcaaa gaccaacaaa aatattagca
     1021 gctagtttca aaaattgtga acaagtcact acagccattc gatctggagc tcatgcgata
     1081 acgttaggta aagagctact agatcaagta ttagagatgc cctcgattga taaagcagtg
     1141 aggggcttcc aagaagattg ggtgcaaact ttccaagcag aaacgattgg tgaactaaaa
     1201 aaggtcgctg attacttctg aatcaatttc tccataaaat aaacgatagc cttctcgaaa
     1261 actcgaggag gctatctgac gattcaatat tcattaattt aaagtttggg tgactattac
     1321 ttatttctca tttaaacgat gtattcccta acctctaata catccttgta actctgaagt
     1381 tacgccagtt ttgaataaat ttcataaaaa caaatgaaaa gtgtcgcata aaaatatctt
     1441 tcgtgtttct ctagtataac agaataagag gaacaagtcc agaagggata tttttagtct
     1501 tttttaaaat aacttttcag tcgagtttga gtttatgata gttgtttttg aagcgatacg
     1561 gcaagtgaaa aaatagggaa gcatgaaaga atctacttaa tggcgcattg attcatgtga
     1621 tagaaataaa aaactttttt aaattatatc ctcatgattg taacaaatcc agtgatttgt
     1681 tttggtacaa ataaaaaaag gccccgatga agttgtggca aaagtggttt gcctcaaaaa
     1741 taagaaggaa tttccaaaaa tcacttctca aattttgcca catccccaat tgggtcaaat
     1801 ttgtttattt gaatatattt tttacataag gatctttaat agttacattg tcttttttca
     1861 tcactttacg gattgtttta tccatgaatt ccgtatcaag agtttttgct tcggtagcaa
     1921 ttttttctag ctcagatttg tatttgtctt tattagaacc tttatcctgt ttttttacca
     1981 tttttactag ataatagctt tgctgataag tcgttggatc tgttacagga atgatatcag
     2041 aaacttcccc gttttttagt ttaaatgctg ctttttttac ttcagtagga atctctggat
     2101 tggttgaatc aaaattcatt tttccatcag tttcctttaa tgttttattt tttccataag
     2161 cttgaacaag cttggagaaa ttttcccctt catttgcttc tttttttgct ttatctgctt
     2221 cttctttagt cgaaaataga atgatctgtg tactaacttc tggatagaat tctttccaag
     2281 cagtgtctag atctttatct gttaatttta cattggcttt caaaccgtat tggaaagcca
     2341 gcatctgttt aaagagtttc ttatatgtct cttctgtttg gccaactgct tttaattgtt
     2401 ccttgtagtt tggaccgagt tttttgattt gttcattata ttcttttgtt acttcctttg
     2461 aagaaatctc ttttccgtat acatcatcaa atgctttgaa gacaatcatt ttttttaata
     2521 gtgtttgatt atttgattta acttttgggt tatcataaaa atcctgaact gtaagtgttc
     2581 cacctttaaa cgttgcaatc gtttcattgg acttgctaca acctgagaat agtaaaattg
     2641 cacatgctga aaggcacata attagtagtt gttttttcaa aaaatttccc atcctttcct
     2701 tattaaaaac agtctaacag aagaattagg gagacagtct ttcattttcg taaggttgct
     2761 gtagatattc ttagttcgta aaaatctatt ctctctatga tggagaacat ttacatagtt
     2821 ttcacgagac aagaaagaaa agggttgtta aacttaatat aaaggaggga tgaaagatga
     2881 tcaggattat tcggttgatt ggatctgttt taatagtctt agttggtttt gttttaggaa
     2941 ttcttgtcaa taatgcactt gcggatatgt ttattggaaa tagtgaatgg attggagcaa
     3001 ttgccggtac ggtcggacat ttagctgttt ttttactagc tttatttctt gctagtaagg
     3061 tcgaaggaaa aagaatagaa gattatggtg tttctgttcg aggaaaagac tgggggtatt
     3121 tagcgggagg tctcgttgtt ggaattggag tgtttctgct tattactagt ccattatatt
     3181 tgacgggggc gtatcggtta gattcaggaa acgcaaacat tgtgccgctg ataacgagtt
     3241 ttattttatt tattgcagtg ggggcatcag aagagctttt attccgtggc ttttttcagc
     3301 atcagatgct tagatttggt ccgttaatag caatgattgg atctgctgca ttatttgctc
     3361 ttttgcacgg attgaatcct aacatgacat ttctggcagt tttcaatatc tttttagcag
     3421 gttgcttttt cagcgcactt atctacagta caggaagttt atttacggct attggtgctc
     3481 atattacttg gaattggaca caaggagcta ttttgggtat accagtcagc ggaacgcaag
     3541 aacaaggttt tttctccact ctgatccaat cgcaaaatac aataattact gggggaaact
     3601 ttggggctga agcatctata tcaactacat tattcttgtt agtcttgatt gttggtttgt
     3661 tactctatgc atataaaaca aagcggatga agaaatacac tgctgtttat caataaaaga
     3721 tgaagaaagc aaggctgata tcggtcttgc ttttttaagt ctgtcattga ttaaacgaaa
     3781 aagtaaacaa attcaagcga atacacgaca tcttttgtta gattttcaca actgactgtc
     3841 gtgttctcat cattttcatt ttatataatt cctttatcaa atagaaggta attatatgga
     3901 gagtgataga aatgaagaaa acagcgaccg tattatttgt tattcttggg ctgagtataa
     3961 ttgcagcaat gattggaatc agtacttctg caaatgaacg ggcaaatgag aatctttcat
     4021 ttactgtgaa aactgatcgg attgtttatg acatgacaca acaagtcatt actattccag
     4081 tcaaaccaaa caaaagcgtg aatgctagtg atgtacatgc tgttctaaca tatggttggg
     4141 atggtaatgg aagttcagaa aaagttattg gggaagttta tttaaaagac gtacaatgga
     4201 ccgctggtat tgagtataca ataatgattt ctgcagaact atcgattgat gagatcaaga
     4261 gtaaagataa agttgatttg attgtttttt atgatggaca gatgacgatc acggagaatt
     4321 tgaaaccaag cagttggaca gttgttggac cgccaagcag tacggatagc acaagtagtg
     4381 aaagcagtac agaaaacacg agcggtgaaa gcagtacaga gagtacgagc agtgaaagta
     4441 gcacagaaaa cacgagcagc gaaagcagta cggagagtac gagtagtgaa agtagcacag
     4501 gaagcacgag cagcgaaagc agtacggaga gtacgagtag tgaaagtagc acaggaagca
     4561 tgagtagtga gagtagcaca ggaagcacga gcagcgaaag cagcacagga aaagtaaata
     4621 atgaacttga tttggtacct atcataccaa ctaaggaaca aaagagaaat gcagggagca
     4681 acctaaaaag tgtgctaaaa cagcctgatt ttgtttctcg tggaattgat catcaagaaa
     4741 aagcgaaaga aacagataat agaaaaagcg atttaccaga aactggtagt agaaccttga
     4801 acaagctaat tacatggatg ggtgtgttac tcattttgat tgtaggagca agctattttc
     4861 gttctctctt ccatcgagtg aaataaagaa taaaagcaac agatctaaaa ttgaataaaa
     4921 cgatagattt ttgagtgaat atttcattcg agagtgctgt attgcctggc gaagttgtag
     4981 ctttgccaga tctatttttg tttactaaca tatttgagaa acaggaaata acaggaacac
     5041 aaatggaaaa taagagcaag aataattgac aatgcacact gcgcatggta gtatctctga
     5101 aaaatcagta acgaatctat ttgtacgtta ttcatgtagc tgtcggaata agtctaaata
     5161 atagataaaa aggagtatgt actttgtttg aagaatttat tgatatcaat gaaaggcaag
     5221 tatatcaatt tttgaactat tgttatgaaa gagacgagaa attatatgtg gtgaaggata
     5281 tcgctttaga tctaaactac accctggcta agatgaattc ggtgattcaa caagcagaat
     5341 cgttttgcga aaggtatcca gaatataaat tatcttttct ttcagaaaac aagatgataa
     5401 aagtcgagtt ttcttctcag tttttactga gtaaagttta ttctatactt ttagagggaa
     5461 cgattggtta tattttactg gattcacttt acaaaggtac ttatcaatcc ttagaaaatc
     5521 ttagtcaaaa aattatataa gtttgcgtac gattcaaaga aaattaagag aacttaatac
     5581 tattttgaaa aactatcatt tatcttgcag cttgaaaaaa ggtaatccga tagaaggaga
     5641 agaataccgt atccgatact tttttcactt gatgtattgg cagtcattcg acgaaaatca
     5701 ttctgatata ttatcaagta taaaaaataa acgtcaacta ttagaaaaat ttgcgaaaca
     5761 tgcgccatat acgcgtagta tagatagaaa gaaatggatc agcctactaa gaatttcgtt
     5821 gcaacgaatg aaacaaggcc actcgattac gtatgtccca gaagagatga acaaatttgt
     5881 gcatccattg ataacaaaag aagagtttac gcattacata ctagagcctt tttttgaagc
     5941 aaacttctgg tcgatgaatc acatcactcc aacagagcaa gcttaccttt attttatgtt
     6001 tggtgtaatg aacacctatt tggaagaaga tttgttggat actccagata aagtacaaga
     6061 aagttggggc tggattgaat cgtctattgt agaaaatttt gaaaaaaact tcaagatttg
     6121 ttttacaact tcagaaaaaa attatctata tgtcaatttg gcaatgatcc atttgtattc
     6181 aagggttttt gggacaaaaa agaaggtgga tgcttttgga aaatcagcag aagacagaga
     6241 ttttcagcat atatttccag tgatgtatcc aatcatgcaa cagtttttta gtggggtagc
     6301 tcgcagaatt ccagagctta atacttatta tgaaaagaac agacggttga tttttcaata
     6361 ctgtatgtta gtcagggata tttttataaa acacgaacaa cctgtcatat tctatattca
     6421 atcaaagtat ggtaaaacac aggaattatg ggcaaagaaa aggatattat ctatgactga
     6481 acgcccaata aaatatagtg catccgctga tcagttacct gatattgtca ttagcgatta
     6541 tcctatcgac aaaaaggcat atgatcaaac gaatacacag atattttact ggaatggaca
     6601 acctacaaaa aatgattggg cgcgtctgaa agctgaaatc ataaaaatca ggaatgagaa
     6661 aaatagatcc atattggaaa aattggattt cgttaattaa gaaaagcaga ttgtttatgc
     6721 caaaattaag acattgcaaa aagattattt tctttaaaat cgacaagatg accagaaagc
     6781 aagagttcgt tgagctcttg ctttctttta gttttagaaa ggaacatcct gattttatct
     6841 tcgctaaatc cagtcaaaag ttttgcagat tggtcgtaga taatcggttt tttcaataaa
     6901 gaaggggatg tacgaatctc aatatatagt tcactcaaac tgagttcatc tattctgtga
     6961 acaagatttt tataactaat agaatgagta gagagcattt cggtcacgcc gttgtttgtc
     7021 aattttagta agtggataaa ttcatttttg gttagtggtt gacgaattaa gttctgttcg
     7081 ataaacggta tatcatggac gataagccaa cgttttgcgc gtcttgaaga cgagcagcca
     7141 gaacctgtat acaatttaat catcatacat tcctccaata gctaagtatt tatgaaataa
     7201 taacatgaag aaatagtcga aaagtgccat ttagaggtgt aaaataagaa aatgttgtca
     7261 cgtataatgg aactagctag ataagaaata ctattaaatc aagaaaaaag aaagaaggca
     7321 caagtatgtc aaacacagcc gacgcaatag tagtgatcga tttacaaaaa ggggtatgtt
     7381 ttgattcttc gccgatacac gaattagaaa cagtgacagc attagtgaat aaaagaatca
     7441 aaacatacga aacgattggg aaaccagtta ttttcgttca acacgaagat gctcaattag
     7501 tgccacaaac aaaaccatgg gagctattgt cggaattatc tattcctgag cacagttatt
     7561 ttgtgagaaa aacccatgcg aattcatttt ataagactaa tttgagtgtt ttattaactg
     7621 aattggactg tcattcgatc gaattatgtg gggcacaagc agagtattgt atagatacga
     7681 ctgtgaagtt tgctcatgga ttaggatacc agcttatgat gtgtagagga gcaacgacaa
     7741 cttatgataa tccttttatg aaagcaaagg aaacaatcgc tttttacgag aaaatttggg
     7801 ataaacgatt tctgacattt ttggagcaat aagttgtttc ttcgtttaaa aaaagcagaa
     7861 tggatactgg tttatccatt ctgctttatt acgtaaaatg agaaaataat cctgttctat
     7921 ttttatggga taaaccattt attttttgta taaaaaatgt ttgcgtttac atataattct
     7981 cctagaaaca taaaaaggag tgaatagctt gagaacaaaa caagtattaa agggagcgtt
     8041 ggtcatctta tttgctgtaa gtacaagcgt cccgcaatgg acagtatatg gagagagcat
     8101 ttcttccgaa tcggaatctc gggaggtaga aaccacagaa actactgatg ctggaaatga
     8161 aacgaaatcg agtacttcac aaacagaaac aaatactgaa acaacggttg agacatctgt
     8221 tactagcaca gatcaagaaa cgaccgctac cacagataac caacaaacag aagaagcaac
     8281 agctacaaaa atgtcaaacg acgaatcctc ttctgctaaa gtaagtgaca aagagaatgg
     8341 gacagaaaat gatgatatcg gtaaaggtga aaatttcaat ggtaaagaat atttgaatta
     8401 cttcggtaaa cagatgacag aaatacttaa tggaccaaca gaagacatca agtcaaaatt
     8461 aatagagtta ttagtcactg agcttgctgt taatgattat ggtgtagata aagagattat
     8521 caaacatctg attgctactt atctattgta cgatatcgct tttgcaaaaa acagtgtgtt
     8581 gatgtcgatg cttggaggta cagatgatgg gacaacgcct acagaaaaca caggcttcta
     8641 tccaaataca aaacaacttc atcaaactgt actaaacaaa caagatggca aaatgatgga
     8701 tgtatatgca tattatgtcg atcaaggttc agataaaaca gtcatgatcc atggcggatt
     8761 tcgagggaat tggaataacg ggatcgttac agaagaatac aatgattttt ataaggccgg
     8821 gtataattta ttatttgttg attccagagc gactggtaat agcggaggcg attatgtgac
     8881 ctatggacaa tatgagtcag atgacgtcct ttactggata aatcaagaag ttcgagagcg
     8941 gccatctcaa aagattttac tttatggtgg ttcgatggga gcagctacga tgatgtctgt
     9001 attagcgaaa gatattcctg tcaatgtcaa aggaattatt gaaaattgcg gatttgcatc
     9061 aattgatgaa caactacgtt ttacgtacag ccagacagta gcccccgcac taccggatgc
     9121 cataaaaaat cagttagaca tcattgggga tcaagagcat gaagatttat ttatgggcct
     9181 tttgaaacaa tactattttg atcaggagat gcatttggat acaaaagctg ctctacctac
     9241 gattggaatg tcagattcat tgcctaaatt gattatccat ggaacagcag atgatgtagt
     9301 acctgtgtct aacgcgcaaa aattatatga gttatcagga gggtataaag atcttttatt
     9361 agtagaagga gcagggcatg gaaaggcaca ggaagttgac catgctgcct acacgaaaca
     9421 tgtaacggac tttttgaaag tagtgttcca tgatcagata aacgtaaagt atgtggatga
     9481 aaacaataaa agtctactca aagaccagga cgaaatccag ctttacggag cttatggaga
     9541 aaattatatg acagagcaaa agacattcga aggatacgaa ttagcaaatg ttgaaggacc
     9601 gactgaaggg atttttaatg agacgatacc aactattatt ttctattaca aaaaaatccc
     9661 agtagctcca ccaaaaaagc aagatccgac agagaatgca gacaataagg gaaagaatga
     9721 acctcgagag gatcaatcaa gtgatgatac gcaaccgatt cagatgacag tgaaagtaca
     9781 aaaaaagaca gatgcaaaaa aaagaatgtt gccgaaaact ggagaaaaga aacattcgct
     9841 tctcatttat tcaggtggat ttttatctgt tagcacgatt atcacatgga tttggcgaag
     9901 aaagagaggg taaatgaatg aaatggttca agcgaatagt gattgcagta ccagttatca
     9961 tcgtagttat tttagtcact gtatttttga ttaatcaaat cacaccaaag ccgattagct
    10021 tgcttgttag aaaacaattt gacacaagtg aaaaagaaca agtatatgcc cgaccagatg
    10081 atttccagca aaaaatcgaa caaatcgata taaaaaaaga aatatcctat ccttcaaagt
    10141 acaaaaataa taatatggat atctacacac cgaaagtgga aaagaaaaaa ttaccgattc
    10201 ttttctggat gcatggaggc gcatatgtag gaggggataa aaatgattgt cgtgattatt
    10261 tggaatatct atgttcagac acgcagcaaa tcatcgtaaa tatagattat gaacgatcac
    10321 cggaagcaaa acatcctaca ccagttatcc aattgaacga agccattcaa gcagctaaaa
    10381 aagagataaa agatcaagca gattggtcga atatttcgat tggtggaaat tcggcaggtg
    10441 cacaaattag tggagaatat ttgttagcac ttcaaaatga agaaattaaa aaagctgatc
    10501 atcttgatcc gactttggag aacaagcaga ttacgaagtt tatttctttg tctggtctgt
    10561 tggatccttc tgcacttact caagtaagtg ataaaatctc tagctttctt tatgaaaaat
    10621 gtggatgggc ttactttgat aataaggact ttgaacaatc agagaaggtc aaaagtttag
    10681 ccttggtcag acatgcggat cgttggacgc aaaacacatt cttaacggat ggaaatacaa
    10741 atacgtttac gaaacaaatg gaagaagtaa cttctgtatt tgagaaagcg ggggtgaaag
    10801 tcacaaaagt agattatgcg gagaaaaatg ctgttttgaa ccatgaatat cagtttgatt
    10861 tcagcaataa acaagcgcaa gaaacatatc aaaagttagt aatgtttttc aaggagtaaa
    10921 gtcttatgat gcaaaagagg ttgtaatctg tcacttagct ccaagtcaca aggagcaatt
    10981 tcaataaaca agcttttcat ggtttatgaa tattgtaact tgtgactgag gagttagaga
    11041 tggcaagggg caccttttat tcgaaatttg ggaatatcac acgattattg tcacgatctc
    11101 ttttacgtaa attttataag tcagatttgt tgttttgatc gtttaaaaaa agcaacaaat
    11161 ccgaagcctg cggaggcaag aagggacaaa aagccgagtg gtaagcaaaa gaatgctggt
    11221 tccactaata ttccgttgtt attgatataa ggctgggaac aaagatgaat agcaaataaa
    11281 atcaatgcac tagcgaaaaa aagcaaagaa atatggatag ctttcataag cagcacctcc
    11341 ttttttataa ttgtatgata aatagattaa gaatctataa atgtgacaag tttgttagga
    11401 tgtgaataaa atgatcatct agcgaacttg aaacaaagat ggctaatgat aagcaattaa
    11461 tgattcagca atcagatagg tacaaagttt accatcatac gtctagacca ataatagaaa
    11521 atatgggaat ataatagaaa agatttagga tacccccaaa agaatttccc caaaaattcg
    11581 atgtatccta aactttttta ttttacataa caatcatatc aactgtgaaa taaaattaca
    11641 aatgataacc taaaatgagg ccaaaagcca gtgttatcaa ggaaatactt aattcaccaa
    11701 aatttttttt aattttttag aaaataagaa acaaaaataa taaaaaaaag aaaagataaa
    11761 ttttttacta ctgtatacta actttgttat cgcatctaac aagtaactcg aataatacca
    11821 atacaacctt ctccaaagat gcgatgacat acgttctaac ccaccgacta ttgatgttct
    11881 gtaccaccct tgcagaacca aaaaagccac taccaaatat ttggtagtgg ctttttttgt
    11941 tttatggatt tttcgctttt tctgttatgg tgctattctt tgatttcaga aatagtatgt
    12001 cgaactttag cgatagaacg acgtgattct ttttcgttgt aaaacatcaa aatcacatat
    12061 agagagtcca aaatgcttag ttgagaaata cgggaagcta aagcttcaga tcggaattct
    12121 gtttcttcag aaatagaaat aaaaacgaca tcgccaagtt tagcaaggga agaattagct
    12181 tggctagtaa taacgattgt ttttgctcca gtttttctta cggtttcagc aatatggatt
    12241 gtttcttttg attgccctgt gtgagaaatc aaaacagcac agtctttttc cgtcaataaa
    12301 gaagcttcca tcaattgaat atggtaatcc gtgctgtgag aagttgcgat aggggaacgc
    12361 aaaaatttat gataagcgtc agttgctaca atctctgaac cgccaacacc gaaaaaatag
    12421 acacgtttag attcattgat aatagtagcc gcttttttta gatccttttg ttgtaacaac
    12481 ttttttgtgt catttaaagt tgaaatacta gactcgaaca ccttttgcgc catagtgagc
    12541 tcagtatctg ttttctgaat attttcgtgg atagaaatag cagatagatc attttcttgg
    12601 atcaacatgg ccattttaaa atctttaaat ccattataac caagtttttt tgtaaattga
    12661 aaaaaagtag agtcagcaat gcccagttca cttgctaaat tgctaatagg actatgactt
    12721 actttgcttg gattttctaa aatataatcg gcgatagcct gttcttttgg gctgaagtcg
    12781 ttgtacattg ttttgatttg tagtcttatg gagacgctca tgagaattcc tcattttcat
    12841 aataagatta tcattttttc cgttctcatt aatgttaaag atacaaggag agtaggaaaa
    12901 aatcaaacaa aaaatatttt tgtaaaatct atttacaaaa aaattttttt gtataatgag
    12961 ggtataagaa atggaggcgc tatcatggaa attggtgtaa ttggtttggg aaaaatggga
    13021 ttgaatttag ctttaaactt aaaagagcac catcacaaag tacaaggact cgacatttca
    13081 agtacagctg ttagtcaggc aagagaaaat gacattcctg cttatcaaga gatctctgaa
    13141 tttctagcta cttttgagca gaaaaaaatc atctggttaa tgcttcctgc tggagagata
    13201 accgaaaaca tgttaagaaa actttttcca aaactcggac caggagacat tattattgaa
    13261 ggcggaaact cttattataa agattcaatc cgtcgagcag aagagtttca gaaaaatgaa
    13321 atcggttact tggattgtgg gacttctgga ggaatcgaag gagcacgaca tcaagcctgc
    13381 ttaatgattg gaggagataa agaaactttt ctatccgtgg aacaattatt caaagatgta
    13441 gcaattgaaa gaggatatct gtatgctggt gcatccggaa gcggacactt cttgaaaatg
    13501 atccataatg gaatcgaata tggaatgatg caagcaatcg gtgaaggatt ccaacttgta
    13561 caaaaaagtg agtatgcttt tgacttggaa caagtcgcac gtgtttggaa tcatggttcg
    13621 gtgattcgcg gctggctgat ggaaatcatg gaagatcagt taaacgaaca tcccaattta
    13681 agtaattatc ggggaatcgt ttctgcatca ggtgaagcaa aatggacggt tgaaacagcg
    13741 ctagaaatgg ctgttccagt tccagtaatt gcaactagtt tgttcatgag gaatctttca
    13801 caggaagaag atagtttttc agcaaaagta gtttcagcac taagaaatgg gtttggcgga
    13861 catgaaatag ttgaaaaggg tgagtaaaat gccagattat catatagcaa tcgttaattc
    13921 cagcagtttc ggaagagtct ttccacacca cttggaaaga ttaaagtcag ttggagacgt
    13981 tcatttcttt actgttgatc aagagattcc aggaaaagaa ctagcggagt tacttaaagg
    14041 attcaatatc attattgcaa gtgttacgcc attttttcga cgagattttt ttgaaaacaa
    14101 agatgaactg ctattgattt cccgacatgg tattggttac aacaatattg atttaaaagc
    14161 agcaaaagaa caccagacaa tcgtatctat catacctgct ttagttgaac gaaatgctgt
    14221 agcagaaaat aatataacta atttgttgtc catgcttcga cgcacgacac aagcacaagc
    14281 aagagtcaag gacgatcgat gggaagatcg ggcggagttc gtcggtagga cgctgtttaa
    14341 caaaacagtt ggtgtgattg gtgcaggaaa taccggaagc ggagtaatcg aaattttgcg
    14401 taacggtttt cgctgtgatg ttctagctta tgatccttac aaatcagatt tatacatcga
    14461 aagctttggt gcaaaaaaag tagaacttca agaattactg gaacaatcag atatcatttg
    14521 tttatgtgcg aatttgacag aagagaacta tcacatgatt tctgataaag aagtcgatca
    14581 gatgaaagaa aatgtttatc tatctaatag tgcaagaggc gctctagttg atgaagaagc
    14641 gatgattaat ggtctgaaaa gcggaaagat cgcaggatat gccacagatg ttttagaaga
    14701 agaaccggga cgtcaagatc atccgtattt agcgtttgaa caagtagtga ttacgccaca
    14761 tatatcggcc tacacaaggg aatgtttaga agcaatgggt gaaaaatgtg tcagagatgt
    14821 cgaacagatc agtcagcacc ttcttcctga acgttctgtc cagacaaaga gcaactatat
    14881 aaaaggatga tgaagaaaat ggtgaacggt ttaaaagtga aaacaggccc tcaattttat
    14941 ttatatgaag aaggtggtat ttcaaaagtt tctgatctct tgaaatcata cggcgcgaaa
    15001 agagtactgg tcacccacgg aacggtatca tgggaaaagg cgctacctaa attagtattt
    15061 ttgaatgacg aaacgattca atttttttat catcgttatt ctggagaatg tagttatgct
    15121 gaagccagac gaatagctac aatcatcaaa aaaatgaaat cgatttcgta gttggcgttg
    15181 gcggaggaaa actgaccgat ctagtgggtt atagtgccaa tcttgcaaga atcgatttcg
    15241 gagtcatccc tactttagct agtaattgtg ctccatggac acctcttgct gtcatgtata
    15301 aggagaatgg acaagcagaa gggaaaacag aacactttta cagacaagct gcttttttta
    15361 taacagatcc ccaattagtg attgattcct ctgttccata tttcattgcc gggttagcag
    15421 atacactagc aaaatggtat gaatctgagc tcatcttaga acaagatttt ttgcaagatg
    15481 aatcattttt gaagctagca caagatactg cgaagatctg caaagaagag attttgaatc
    15541 attctgctaa agcaatccaa gatatggcac aaagaaaact gacatcggag ttcaaacagc
    15601 tttcagagat tatctttgct gttgctggtt tagttggagg attaggagat aaatacgcaa
    15661 gaaatgtggc agcacatgct atgcatgacg ctatcagtaa atatattccg gaaagccatc
    15721 gttttctaca tggagaaaaa gtagcgtatg ggattttcta tcaactggca ctagaaggtc
    15781 gctgggaaaa aatagacgag ttatatcctt tgtatcggga attagaactg ccggtttctc
    15841 tagaacaaat gggattattt ccgaaagata aacagataat agataaaatg gctgaattta
    15901 ttgattcgaa agagaaagtg catttgattc ctatagaggt aacacagaaa tcactgatac
    15961 agtcaatgat ggaactggaa ggttatatca gaaagatctg aaggaggagg acacatggaa
    16021 acattaagtg tagtacaaag tttgttgatt gctttatggg tagccgcggt tatgtcccgc
    16081 tggttaggtg gaggagccac gttgacctta cgtttttctc ctttgatgac tggattagtc
    16141 gtcgggttga tcatggggga agttgcacaa gcgatgattg ttacagccgc tttgcaaatg
    16201 atttatatgg gggttttttc tccaggagga tcaatgccag ctgaaccatc tattgcagca
    16261 gctatcgcag taccagtcgc attattaggg gatctgtcgc cagaagcagc gattgccgtt
    16321 gcggtgccag tcggattgct cggaagttac ttgtatcagt ttcgtttttt catcaatact
    16381 tttttaggta aatatacaga caaagctgta gaagatttga atacaaaagc tatggcccga
    16441 tcaattattc tttatccaac ggttgcctca tttttattat tcgttccgct tgttttcatt
    16501 gctttatatt taggggcgcc attgatcgct gatgtaatca aagctttaga gggaacagtc
    16561 gttatccaca ttcttgaagt agtaggtgga gggttagcgg caatcggtat cgcgacaact
    16621 gtatacgtta tcggtcgaaa agattatctg gtctttttct tccttgctta ttttatgagt
    16681 gttgttttga aatctttaga tattacgatg gttacttatg ccatttttgg gattattatc
    16741 gctttgatct ttgtccagtc gcaaaaaggg aaacaagtac agcctgccac aagcaataac
    16801 aattcagcat cttttgatga cgaagatgac tatgatgacg gattttaatt taggaggaat
    16861 gggaaatggc tgaaataatg gataatcaaa caggtgctcc tgaagaaatc acgaaaaaag
    16921 atgtaacaaa agcctatctg agatggcatt ttgcaaacga aattcctcac tcttttgaac
    16981 gttacttggc gccatcacta ctatacggaa tgatgccaat cttgaaaaaa ctttataaag
    17041 atgaagactc tttaaaagca gcatataaac ggcagttact gttcttcaac actcaattaa
    17101 gctggggtgg cggtgtgatt actggcctaa tgtcttctat ggaacagcaa agagcagaag
    17161 aagagtatga agaaaaagag atcttgatgc aggatgactt gatgtataac acgaaagcgg
    17221 gattgatggg ggcactagca ggaatcggag atgcaatcga ttcaggaacc gtccaatata
    17281 tttttatcgc aatcgcggta ccttgggcac aacagggaag tcctttaggc gcactttttc
    17341 cttttatctg ctttgggttg tatcaggttt tactaggggt atttttcgca agacaagctt
    17401 tcactatggg ccgtaatgct acaggcctaa agcaaaacac tggtgttcag acagcgattg
    17461 aaatgctatc agttttaggg ttgtttatga tgggggtgct tgcgggaaac tatgtaaaag
    17521 tagaatcttc attgaaattt gcgatatccg gacgtgagtt tgttatccag gaaattcttg
    17581 atcaaatcgt gccagggata ttacctttag ctgtcgtaat gggtgtgtac ttgttctata
    17641 cgaaaaaagg attgaaagtc acacaagcat tattatggct gactggaata ttaattgtgc
    17701 tagcaggaat cggtatttta taaaaagaag ggaacgtgaa taagatgggt gtagtcaatt
    17761 tagcgcgtgt ggatgagcgt ttgatccatg ggcaagtaat ggtaacgtta tctcaaaaaa
    17821 gtggagtgaa ttccattttt gttgtagacg aagttgtagc aaaagataaa tttatgagag
    17881 atctttacaa aaatgcagga agccgtacag gacaaaaaac aattgtcatt acaccagaga
    17941 aagctaaatt ctattgggat gaatatcaat ttaaagaata caattgtatt ttgatcgcaa
    18001 aaacagtcca aacgatttac gacttagtaa aacacggaat ccccatggaa gaattgaata
    18061 ttggagggat tgctcaaaaa aatcctgata cagatctttt agtgacgaaa tctgtttatt
    18121 taaataaatc agatgctgaa aaattgaaag aaatgaatga acaatatggc gtaaagaata
    18181 tttattttca agccactcca tctgcaccta aaacaggatt aaaagatgta ttgaacaagt
    18241 ttgatttgtc ataaacaaat gcttagaaaa aagataaaga gggcgaaaaa atgaagaaga
    18301 acgagctgtt tcgtgattgg gaatttcgtt atcgctatat ttaccgtaag cgccgtacaa
    18361 aaaagagtaa acagcgtttt ctttcagcat tagtatcaga tatttacagt atgagaacag
    18421 atgtgacagt cattgcttac gatacgctag cctaccgatc aaaaaatatt tatgttggag
    18481 atatcgaaaa agcagagaaa gttatctgta cttattacga tacacccgtt catgcattag
    18541 gaagttattt catgtttgat tggaaagacc aaaggaaaaa aacaatctac tctatattat
    18601 tgtccttcat tttgttgttc agtttaggtt ggtggggaat gatgatatat aacaaaaatc
    18661 ctcatcacgt attcgatctg ctatccgtat aaacaggtat cactgtacta gcatttggga
    18721 gctacttttt cttattggga aaagcagctc gcggatggcc tagcagacaa acttttattc
    18781 gaaatacttc atccatatta acgatgctag aaatgatccg tacgattgat gatccgagtg
    18841 tagcgtatgc gtttgttgat gaaggctgtt atggagaaaa gggcttagac agcgtgagat
    18901 cgggtatgaa aaaagaggct attctttttt atctagactc tgttggggca gatacaccgc
    18961 tacagttttc gggaaattat ttttcaaata aagaacagtg gctgaaacaa gttgataagt
    19021 tgaaagaaaa aaacgtcaat tatattttta gtgcaagaaa aaagcaagcg cagttcttct
    19081 atttgaccaa aacagattta cgagggaaaa catttaattg gcaaaatgcc aatcagatta
    19141 ttgctctttt tcgataagta aaaagtgcaa aacaaggagt gagaagacta atgttggaaa
    19201 tcatgatcgt tacacatggt aagttgagcg aaggactgaa agatgcggcg gaagtaattg
    19261 tcgggacatc gagccatatt gaaacaatgt gcttagagtc tggggaggac atccaaacat
    19321 tcggagagaa ggtcaaagaa aaattaacta tgatcaacac agcagaaccc atgctagtat
    19381 ttgttgatct aattagcgca agtccgtaca atcaagcgct cttggcagtc aatgaactga
    19441 ctgaagaaaa gaaagcagcc acttatgtca tagggggcgt gaatctgcca atgttgttag
    19501 aagcaatcaa tcatcagatg cttcacacac cgatagaaga agcggtggaa caaattgtca
    19561 aacaaggaaa agataattta actgtttggc atgcttcagc ggaagaaaaa aaattagatg
    19621 aggacgattt ttagaaggaa ggctgaaaag atgaagtggg gatttagatg gtatggtgaa
    19681 aaaggggatt cgatcccatt aaaatatgtt cgccaaatac cgggaataaa tgggataatt
    19741 ggaactttgc tgactaaaat gcctggagat gtttgggaga tttcagaaat tgaggagttg
    19801 aaagcatctg ttgagagcca aggactggaa ctgcttggaa ttgaaagtgt agcgatccac
    19861 gatgcaatca aggcagggac agatgaacga gattactata ttgataacta tatacgaaca
    19921 atcaaaaact tgtctcgatg tggggttcga ttgatttgtt atagcttcaa accaattttt
    19981 ggatgggcga aaactgattt gtttaatgaa aacaacgatg gaagctattc tcttttatac
    20041 gatcagaaaa tcgtcgatca gatggagcca ggagaaatgt atcaattgat acacagccag
    20101 tcaaagggat tcaaattgcc gggttgggaa gaagaacggt tgaaaaaatt cgctcagctg
    20161 gaaaaactgt atgaaggaat gaccgaagaa gaattatttg aaaatctgac ttatttttta
    20221 gaaaaagtga ttccagtgtg cgaaaaagca gatgtaaaaa tggctatcca tccagatgat
    20281 ccgccatggg aactttttgg ttttcctaga gtgacgaaaa atcttggcga cttgaagaaa
    20341 attctaaatg cagtagattc tccatataat ggactaacgc tgtgcacagg atctttaggg
    20401 gcaaatccgg aaaacgattt agttgaaatc atccatgagg taggttcgcg catccatttt
    20461 gtccacttca gaaacgtgga gtttttagga gaaagaaagt tcaaagaaac ggcacatccc
    20521 tctacagaag gctcccttga tatgtatcat attatgaaag cgttggtgca agaagggttc
    20581 gacggtccta tacgccctga tcatggtaga accgtgtggg gtgaagtggc tatgcctgga
    20641 tatggcctgt atgatcgtgc aatgggactc acttacatgc aaggtctata tgaggcgata
    20701 agtaaggaaa aaccactggg agagcattat gaataaaatc aagctcttca tctttgatat
    20761 ggatggcctt ttattagaaa ctggacgttt agcttatcgt gcttatgtaa aatcagcaca
    20821 aaagtatgat tatgaaatgc gtaaggaagt ctattattta ctaactggcc aaacagaaat
    20881 ggcgataaga gaacaaatgg gcattttgta cggagaagat gttccatata tcaaatggcg
    20941 agaagcaatc aatcaatata aagaaaaaat cgtgaaagaa gataagagag tatatacgaa
    21001 aaaaggagca gaagaaattt tatcttttgc aaaagaaaga ggaatccata caatcgtggc
    21061 ttcgtctaat acacgggtaa aagtagaaat gtatttaaaa atggaaaatc tatatgcctt
    21121 gtttgatcaa atcatttcag gggatgatgt aaaaaaagga aagccggaac cagagatctt
    21181 tttgaaagct tgttcaaaaa tgaatattcc tccaagtgaa gcacttgtat ttgaagactc
    21241 gattgcaggg atcgaagcag caaggcgagc gggcattttg tcttttctca tcaaagatca
    21301 tttgataggg ttgcccgatc ataatgggaa gcataagttg aaagtagatg taagtttata
    21361 tgaatccaat aaagcagact atgaatttta tgacctgcat caagcaaaac gatttttaga
    21421 aagtaaaggg ttgtatctct aataaagagg actattttct agtcctcttt atttattgtc
    21481 ctgcacgact gagggaacag atgaaaaaga agtaattttt tattttgaag tatctacctt
    21541 atttgtagtg aacaatttag aacaaacaca aaacgcatct actgttatct accagtagat
    21601 gcgtttaaag agaagaacga gaatcgtcca tatgagggtt tc
//
LOCUS       DAFEKH010000048        20694 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.050, whole genome shotgun sequence.
ACCESSION   DAFEKH010000048
VERSION     DAFEKH010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20694
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.050"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            48..365
                     /locus_tag="LP386_002059"
     CDS             48..365
                     /locus_tag="LP386_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBL1919291.1"
                     /translation="MKEARPRDEIDKLYKTKRWRDLRQVVIARDFGMCQECKRRGRNT
                     RGTIIHHIVEAREDLSLFWSVDNLECICVACHNREHPERSGGKKKPKPKSHIVKMYST
                     PER"
     gene            complement(523..687)
                     /locus_tag="LP386_002060"
     CDS             complement(523..687)
                     /locus_tag="LP386_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzC family protein"
                     /protein_id="HBL1919292.1"
                     /translation="MGELYKPGEDNKPKGTYKEVGPRGGNVQGGQEVKIDPGDRLPPT
                     SQKGNKWTKK"
     gene            789..1310
                     /locus_tag="LP386_002061"
     CDS             789..1310
                     /locus_tag="LP386_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HBL1919293.1"
                     /translation="MPQPAKSAKLQLLNGNPNKKNTEELRKRAAAEDKLKMATDKIKP
                     PLWLDSLGKDTFEFIADELLSVDLISNPDVHTMALYSNWYSQYVSLEKQLRKLQREYK
                     LNYALAKKEAEARGEPFNEPNELIGNPLSRQMDTASRNLRSFGADLGLSPAARAKLAI
                     KMADDGGDDDDDF"
     gene            1297..3087
                     /locus_tag="LP386_002062"
     CDS             1297..3087
                     /locus_tag="LP386_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBL1919294.1"
                     /translation="MTTSNILDMSYTERVDYWQSYLEEQASWGGFLKCPYPELLTTWY
                     AERLIDGSIPASKENIQAAKRHMRDLQRQGTDDFPWIFDEEKGHRPIRYIEKKCKPTE
                     GDFGSFVLQPWQHFIIGSMYGWVHRDTGERRFREALIFVGRKNGKTSLISGLSTYMVA
                     YDDEQGANVYVLANARDQASLLFDKAAEMVKQSPALFKKFGKPKRSSINYAPAFSKME
                     PRASDSRKLDGLNTHFGIFDEIHEFTNYNLINVIKKSRGTRKQPLIVYITTAGYVLDG
                     PLMSYFEQGVDCLEHLEDDIDERTFYYLAKLDSAEEADDPRLWIKANPNICLMNFVGM
                     LDDYVKDKKDPKEYADWITKQFNLFSDIDELSFVDMPTIKRNNKTIDIETLKGKKCVG
                     GFDLSETEDFTAAVLEFPLETGEVFILQHTWIPQARFDRDNNQERIKAWEKVGDLTII
                     PGDYVNYEYVLNWFVENSKIYDIVKINYDKAKALRLNKELENAGFETNEIRQGFLSLG
                     GPMQNFKEMLLDGKVIFNNSKLYRWYLSNVKLVMDRNSNWMPSKQSKSRKIDGFAASL
                     NSHAEVLNMLVNPVGTGKVTYYSISDLMNM"
     gene            3103..4323
                     /locus_tag="LP386_002063"
     CDS             3103..4323
                     /locus_tag="LP386_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBL1919295.1"
                     /translation="MSILDRLRSFGRAKPKASKQEYFLNDPGLIPYLVGKDEISEGIF
                     SVISRVSNVFASLPLKMIDVEFGQPDDCPAYNLLSEGPRYFTKFDFFRDVEVLRNYQG
                     NAYVQIFRNINGEVADMALVKPGACHPVIDMDSGELYYQVTATDKGSYKQVIYVHYME
                     MLHFKQPRFGGLEGTDPTKVLTNTLGYDREVRKISLSQLKGSNEGLKVKFASNMDEEA
                     KKATVKNIADFYRQNGGLLVEENGVEIERLQRELVDSKLLDTDKVSRSRIAMVYNVPE
                     HFIGNNQSSYSSQEQLNMEFLTYNLVPTVNQYEAELNKKTLSRTEKAKGYRYKFNVAS
                     LLRADTQARGQFYQIMRRGGAYSANDVRRFEDLQPINKTGMDDYHISGDLYPIDMDPT
                     LRKTTSSKSVAENG"
     gene            4358..5035
                     /locus_tag="LP386_002064"
     CDS             4358..5035
                     /locus_tag="LP386_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HBL1919296.1"
                     /translation="MKKVTLSGDVVDNDTAWLYDWFGINCISPGKISAALTEAAGDEV
                     ELDISSNGGDVLAASEIYTAIRAYPGKVSGNVVSIAASAASVIACACEPLRISPTAHI
                     MIHNAWVTTSGNAEELKANAEMLSSVDESIVNAYEIKTGLDRKKLADLMAKDTWLNAQ
                     TAVAEGFADEIMFAEAPVTVLNASQPVIPKNAVTKLKNLILKAEAPQEETLLQKKLKA
                     LNGGKNE"
     gene            5032..6225
                     /locus_tag="LP386_002065"
     CDS             5032..6225
                     /locus_tag="LP386_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBL1919297.1"
                     /translation="MNLEQLKNAWVEAGSKVSDLNAQLNAALVDDEKTEEDVVSLQAQ
                     VKAARAKRDGLKEQVANMEAEQVLNVKKEPLDKKDENLKNKFIKDFKAMVNGDPAIMA
                     TLTSNTDESGNAIGLTIPVDVQTTIHTLVRRFDSLQEYVNVEKVTTTSGSRVYEKWSD
                     ITPLTALDTEDGEIPANDDPALYLIKYLIKRYAGISTVTNSLLKDTAENILAWLSKWI
                     AKKVVVTRNTKILAAIDGIKAAQKKDVTDVDGIKDIVNVQLDPAIEATSMFITNQDGF
                     NVLDKVKRADGSYLLQKDVASATGYTFLGKPIKKIASRFLPNKGTQATPKYPLYIGDL
                     KEAVTLYDRENMSLLTTNIGGGAFETDTTKVRVIDRFDVQLVDDEAVVLATFTTIANE
                     TPAKV"
     gene            6240..6566
                     /locus_tag="LP386_002066"
     CDS             6240..6566
                     /locus_tag="LP386_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBL1919298.1"
                     /translation="MILDPKMDLGEIKNALKIDTDDDDVEVSRAAQAAIAYIRGAIGN
                     DKPSFYKQENETVDLINLAILQLADHYYNARSATVSGNLREYDLGFTSLILQLKASYL
                     LFVEEE"
     gene            6570..6905
                     /locus_tag="LP386_002067"
     CDS             6570..6905
                     /locus_tag="LP386_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBL1919299.1"
                     /translation="MPLIQTGNLNQRIKFVRDTTVKDEDGQVVPTSTTILTCWASVQT
                     QRLNDIKTSIGTALEGTLTFIIRYQQKSELTNDMKVRWNGKTFEIITITKGEFAKDFT
                     TIIAKEVSK"
     gene            6902..7297
                     /locus_tag="LP386_002068"
     CDS             6902..7297
                     /locus_tag="LP386_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919300.1"
                     /translation="MSVEVDATEVYKALREVKANVQRVESPALRKAGEYAQEELRQNT
                     PYWDGTKSNGKRGSYMQEHAKNHVVTSSIKNGLVEVGYDKDVSWRMHFIEFGTIKQRP
                     KGFVQKTQKQIEKQVTQIIADEVKRRLGL"
     gene            7294..7665
                     /locus_tag="LP386_002069"
     CDS             7294..7665
                     /locus_tag="LP386_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919301.1"
                     /translation="MKTAVSQVYSILNSNEKTKNIDFYTNSVPESAQTVPSLPVGRIT
                     EISGNYEDFASNNPLTIQFNVQVDVWVSTMKEVDAFYFALDEVMRGNGWQCAYTEQTD
                     DEDLEGAKRIIKRYVANISLN"
     gene            7681..8241
                     /locus_tag="LP386_002070"
     CDS             7681..8241
                     /locus_tag="LP386_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL1919302.1"
                     /translation="MATVGFESVIFGVKTGAGGTLKELVADKSKGGAIEAKITGLGAT
                     SNTTYASNVPFFIASKGVSSPKVTLDVADLMDNGIYSEIIGAKTVDGANVIGSETEAP
                     YVSVVMVTANKEGKRLFMGLTKGKFSHPDIDMKTAEDKGVELQPDSIEGEFISDERGY
                     VYLTAVESEGMTLQKFKDLVNNKEGE"
     gene            8366..8677
                     /locus_tag="LP386_002071"
     CDS             8366..8677
                     /locus_tag="LP386_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919303.1"
                     /translation="MIELQLKLDGKKKTFKQQDISARAMRECIKFYEKAEKADLTDLE
                     AIDSMIAITADIFQDPAVTFDAILDGLTASELVPALESVFEQINELGNNEKKQTASKK
                     K"
     gene            8701..8892
                     /locus_tag="LP386_002072"
     CDS             8701..8892
                     /locus_tag="LP386_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919304.1"
                     /translation="MDQIYKDLIEAGWTMRDVDEADYHYLLHLFGEVESGEEYVDGAD
                     FIKQFLSAEDLVKLEEGGK"
     gene            8892..12740
                     /locus_tag="LP386_002073"
     CDS             8892..12740
                     /locus_tag="LP386_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBL1919305.1"
                     /translation="MAGKGQPAGNIKLGISLDSTSFGNTLDEINAKVKQAESNMRANL
                     KAYDSAGRSYEALSQKTKDLSTVMEGQNAKVRELTKRRDEAISKYGEESKQVANLNTQ
                     INNATAKYNAYSRQLNDTKKELVYSKTAVNDLSNEIKENERQMNAEVKALKAAGDESG
                     AFEAKQKGLAKQTELSEKAIEEQRKVVKLMADEFGDSANETEDAKRALEKLERQSQIS
                     SRQLEALKSSSDQSGKEIEDFGDKSTRSARKLDGLKDKLSSLKSAFSFGAVAGLAHNA
                     ISSVVSGVQGLVGEAVNASDSLMKFSKTMEFANFGKSQIESSKKEMKDYADKTVYGLE
                     EILNTTAQLASNGIPNYTELTKAAGNLNAVAGGSSDTFKSVAMMLTQTAGAGKLTTEN
                     WNQLADAIPGASGLLQDAMLKNGAYTGNFRDAMAQGQITSDEFNQAIVQLGMNDGAVK
                     AATSTDTLSGSWEQMKSTVINGLQSIIEKIGVENITGFINRVTKGIENSIPKITQFIG
                     WLRDIGTWIVENREPLTWIVGIIGGITLAVKALNVASMLLAITGGTLAAPFVAIGVAL
                     GALAGALVIAYTKSETFRNIVNAAFTAVKNVVMSVINNLVEYYKMLWSVLQWLWEKIK
                     EWASWIGNKFIEMKNSVVNTVQNLWNGVKNFFSNGVGDTWNKVVGWVKNIFNKATELK
                     NNVSDVIGNLWNGIKDTFRRGIDTVFNWFSELPTKMKNAIIGGKNAIVDAFKSIFNAA
                     LKAIGKPVNAIIHGASWVLEKLGAEPLQEWDVPQYATGTPAGGHPINGPMMVNDGRGA
                     ETVITPDGRAFIPKGRNVVLNAPKGTHVLTAEETAQLQGSKAPKYRYKKGTNFFGNMW
                     DSVKKVAGNVGHTIKNVVGDVWDFISDPGALARKVLGGLDVLGGLTKYPLEVGKGILS
                     KATSALTEKITGLFSSGNLDTSVGTNGVYKYLADVAKSVMKKFPGFVATSGYRPGDPY
                     SHGKRNAIDIALPGVTGGSPRYTEAANYAFDKFASKIGYVITNGKVRDRSGQSGQPAT
                     GAWEPWPDGDHYDHVHLNGVKDPQNTQISGDSVGGSGVERWRNVAIRALKMTGQYSTA
                     NLNALLNQMRTESNGNPNAVNNWDINAKNGTPSKGLLQVIDPTFRQYAMPGFNSNIFD
                     PLSNILASIRYALSRYGSLTNAYRGVGYANGGIVNQHQIAEIAEGNKPEIIIPLDKAK
                     RSRAMQLLSIAMDKLGVSPKTYGNATTVSSDYEILEAIEKQAATTNQLLSLLLAFFKG
                     NSRTDRDLALDIQKILVRRM"
     gene            12741..13613
                     /locus_tag="LP386_002074"
     CDS             12741..13613
                     /locus_tag="LP386_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate protein"
                     /protein_id="HBL1919306.1"
                     /translation="MRTVLLRNRINEEIDLSTEDYFATGLSNMGFEVKKEHVGQWGNF
                     RESSESVEISEFQSSVIISVHGFREKELYNSLVQFLSEGPFELEFAFDGETMVRRCSL
                     KSLSKTEIDPKTSLLTDTLELYFTSNWYSVKREKLIQRPNVVKTRGKVFPYKRSYIYT
                     QNLWEKKGVFKFNNNSVYLTNSKERMSPLKIRVIGKCSNPYWEVIQNSQIIATDGYFI
                     DMTETQTLEVSSLFEDTTAILKDIAGVESSVYQQQDYTKTNFVQAPTGEFSIVFHVGG
                     ADVEIELYEERDLF"
     gene            13610..14659
                     /locus_tag="LP386_002075"
     CDS             13610..14659
                     /locus_tag="LP386_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919307.1"
                     /translation="MILAVTLFHRDLMLYNEHLFSNSFEFGVDEINEEASSFTMDKYV
                     PVKTGDFLLAKYIPSGKFAYFGVITSQEDEKISCKSLLSLADSEIPTARVSGDNYEEH
                     IRRLIEYYLLNDPTKQLKDILDVKAESATSHSYQATDTNKHKLSAYILNGFKKYNVKW
                     YFKGIQNRKIYTGIRAVNESIYIKDNSSEFSDWDVFVQAPGAGNENKLLIVDKAMKDI
                     EKPIILSTWYLDEENNLTQDGSKENITKPTVNLVNIYDQTAEDKASYEDVAKSELKGN
                     TYSHEIKVNVVRNAKNLNVETIETGMFATISYKGKIYKSVLTAWRISSDKEFVELTFG
                     NIRSRFMDYFEDNGG"
     gene            14663..15487
                     /locus_tag="LP386_002076"
     CDS             14663..15487
                     /locus_tag="LP386_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919308.1"
                     /translation="MVSNVDGYQFENVKVSAENDARLYHVLYNRKNQVIDGYDQSMNL
                     SSSGLTVKVAAGAAIIQGRMVVVRQEESITVPANSSGYIALTVDLTQEVIPGSILPES
                     EEYEWTNNQVKLEFITKVIKGNLNNGDKVYNLPLCSVNSTGSTVSISKISDSYELTLS
                     KGEILWRGTALMHDTQTVQPSKKIWQTVSGFLLVWLPYENGQAIEDRYVTTPFYKERV
                     TFTNVLGEIVSGFDDYHKKWFSKRINYNSNTNIFTGAASNASGDNANMVLRYIVSF"
     gene            15505..17565
                     /locus_tag="LP386_002077"
     CDS             15505..17565
                     /locus_tag="LP386_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HBL1919309.1"
                     /translation="MANLEIKLSANKRQPYLRHRVVGRVGDGGLTTINVQLLEEDEIT
                     PFVINLNGTLKFVGEVSNGNYTEGEPEIIDSTNGLISYTFTKSNFSTSHQFKQAYFEY
                     VDPNGKKVTFQNFIIDVLERVDINSEQAKYYISSLEKLQSEMQTTFNQFISDKQVQYD
                     QIYSKYNELVRLINESDKQVNDRIDQTNQQIGDLGKLKKMYSNSIDFGGYDYSGNPNL
                     LSKLSYDLIENQNTSAGTLSKGENSFKYNKISAEVEGGVELYYKRRGIANWLPSNKTL
                     VMTVKLRAGADYSPVDGKLILIRYRYVDSGTGKIVLDLPINSNSITQEWKEFSITGTT
                     PTFSPQAYHPWIQFRAQDGVLGEIEMSYDIKIEEGSTATPYQPNLLDDSYWLGKTPLG
                     ENLITNAKFPIITRSNPISGFDISEELIIGETYTVSLKGTKPATKEFHLYYGEANYQQ
                     LQYQATLLPVEGLTDVWSATFTARNTSETTNLLRVALWQKPNSATYGTVQIDWLKIEK
                     GDTRTPNISQFKYFGEGLKDSNNPNDYSWDVTPEYTEKSLNNTVSLTEPQSIEGLKNF
                     EDGIQSKGKSVLTSDDNKYEVVTLTVTNGNTGSAKLYREGKTVTIYFFALNGKSSGGN
                     DSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSDYTFAI
                     TYTI"
     gene            17582..17731
                     /locus_tag="LP386_002078"
     CDS             17582..17731
                     /locus_tag="LP386_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919310.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPIPNWKPKFNY
                     WEGNK"
     gene            17728..18174
                     /locus_tag="LP386_002079"
     CDS             17728..18174
                     /locus_tag="LP386_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919311.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGVRSDGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYEALEHENGNLKQLNAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            18176..18313
                     /locus_tag="LP386_002080"
     CDS             18176..18313
                     /locus_tag="LP386_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBL1919312.1"
                     /translation="MFSFSDVKMMYDWGCFTDDQVRLFVPLCITDEEADRIISKEESA
                     S"
     gene            18348..18590
                     /locus_tag="LP386_002081"
     CDS             18348..18590
                     /locus_tag="LP386_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin XhlA family protein"
                     /protein_id="HBL1919313.1"
                     /translation="MKEEALQDVVERLVRIETKLDNYESLREKADSAKDLADKAYSVA
                     LNNAEDIKEMKANNKWSWGYMIGLGITIIGYFLTKL"
     gene            18606..18803
                     /locus_tag="LP386_002082"
     CDS             18606..18803
                     /locus_tag="LP386_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBL1919314.1"
                     /translation="MILPDKYYQVIKWTVLTVLPAASVLVATLGKAYGWNGTDMTVLT
                     INAVATFLGVITGVSAYNLKK"
     gene            18814..19830
                     /locus_tag="LP386_002083"
     CDS             18814..19830
                     /locus_tag="LP386_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HBL1919315.1"
                     /translation="MKKKIILSLSLIMALFLLPINGFAYTINNEFNLGVNEGSSQVAN
                     NQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGSY
                     ANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHLW
                     VTQNIWGDHTDPYGYLSEMGISKEKLAYDLAHGFTDENPTTSDDKPVIDPTRAGAANP
                     TLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVKADGIYR
                     PDVNQAYNTSGNVGYHVSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLN
                     IPKR"
     gene            20020..20093
                     /locus_tag="LP386_002084"
     tRNA            20020..20093
                     /locus_tag="LP386_002084"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20054..20056,aa:Ile,seq:cat)
BASE COUNT         7099 a         3578 c         4595 g         5422 t
ORIGIN      
        1 ataagtatcc agatataaaa acaatcggac acaagagaga tatgcaaatg aaagaagcta
       61 gacctagaga cgagatagac aaactataca agaccaaacg atggcgagac ctaaggcaag
      121 tagtaatagc tagggacttc ggcatgtgcc aagagtgcaa gcgtcgaggg cggaacacaa
      181 ggggcacgat catccatcac atagtcgagg cgagggaaga cctgtcactg ttctggtccg
      241 tagataacct tgaatgtatc tgtgtagctt gtcacaacag agagcatcca gagaggtcag
      301 gcgggaagaa gaaaccaaaa cctaaatcac atatcgttaa aatgtattca actcctgaaa
      361 gataagtttg cagtgaaatg aaggcagccc cccctactct aaaagattaa agagtaaggc
      421 ttgagaagaa cggtgctgtc cttccttcgt aaaaagaccg cttttcaagt tttttggaga
      481 aaaaggaaaa agccgaccaa tttaagccgg ctttggacga agctatttct tagtccattt
      541 gtttcctttt tgagaagtag ggggtaatcg gtcgcctgga tcaattttta cttcttgtcc
      601 gccttggaca tttccaccac gaggacccac ttctttgtag gttccttttg gtttgttgtc
      661 ttcgccgggt ttatagagtt ctcccatagg aatccctcct taacaaattt cggcacagca
      721 ctgccgataa cctaattata aggattgtga taacgatttc aatctatctt ttgaaagaag
      781 gtgatattat gccgcaacca gcgaagagtg caaaattaca attattaaac ggaaacccaa
      841 ataagaagaa taccgaagaa ctccgcaagc gagcggccgc agaagacaaa ttaaaaatgg
      901 ctactgacaa aatcaaaccg ccgttatggc tagattcgct aggaaaggat acctttgagt
      961 ttatcgccga tgaattgctg tctgtggatt taatcagtaa tccggacgtc catacaatgg
     1021 ctctatactc caattggtat tcgcaatacg tttctttaga aaaacagctt cgaaaactac
     1081 aacgagagta caagttgaac tatgcgcttg cgaaaaagga ggcagaggcg agaggtgagc
     1141 cgtttaatga acctaatgaa ttaattggta atccgctctc tcggcagatg gatacagcgt
     1201 ctcggaatct ccgttctttt ggcgctgatt taggactatc accagcagcc agagctaagt
     1261 tagctattaa gatggctgat gatggtggtg atgacgatga cgacttctaa tattttggat
     1321 atgtcttaca cagaacgtgt ggactattgg caaagctatc ttgaggagca agcttcttgg
     1381 ggtggctttt taaaatgtcc atatccggaa ttgttaacta cttggtatgc ggaacgatta
     1441 atcgatggaa gcataccagc cagcaaagaa aatattcaag ctgctaaacg gcatatgcgt
     1501 gatttgcagc gccaaggaac agatgatttt ccttggatct ttgacgaaga aaaaggtcac
     1561 cggcctatta gatatatcga aaaaaaatgt aaaccaactg aaggcgactt tggttcgttt
     1621 gttttgcaac cttggcagca tttcataatt ggatccatgt acggatgggt acatcgtgat
     1681 acaggagagc gtcgcttccg cgaggctctt atttttgttg gacgtaaaaa cgggaagaca
     1741 agtcttatct cgggcctttc cacatacatg gtcgcttatg atgatgaaca aggcgccaac
     1801 gtttacgtat tggcaaatgc tcgtgatcaa gcaagcttgt tgtttgataa ggccgcagaa
     1861 atggtcaaac aatcgccggc gctctttaag aaatttggta agcctaaacg atcaagtatt
     1921 aattatgctc ccgccttttc taaaatggaa ccacgcgcct cagatagccg gaaattggat
     1981 gggctaaaca ctcactttgg tatttttgac gagatccacg agtttacgaa ttacaatctg
     2041 atcaacgtta tcaagaaatc aagaggaacc agaaaacagc ctctgatagt ttatatcaca
     2101 actgctggat atgtattaga tggtccgttg atgtcttatt ttgagcaagg tgtggactgt
     2161 ttggaacatt tggaagatga catcgatgaa cggactttct attatctggc aaaacttgac
     2221 agtgcggaag aggctgatga cccaagatta tggatcaaag ccaatccgaa tatttgtcta
     2281 atgaattttg ttggcatgct agatgactat gttaaggata aaaaagatcc aaaagaatat
     2341 gctgactgga ttaccaagca atttaacttg ttttccgata tcgatgagct gtcatttgtc
     2401 gatatgccta ccattaaacg aaacaataaa accatcgata ttgaaacgct caaaggtaag
     2461 aagtgtgtcg gtggttttga cttgtccgaa acggaagact ttaccgcagc cgttttagaa
     2521 tttccgcttg aaacaggcga ggtattcatt ttgcaacaca catggatccc acaagctaga
     2581 tttgatcgag ataacaatca agagcgtatc aaagcgtggg agaaggtggg agatctaacg
     2641 attattcctg gtgattacgt caattatgaa tacgtcttaa attggtttgt agaaaattcg
     2701 aaaatctatg acattgtaaa aatcaattat gacaaggcca aggcgctacg attaaataaa
     2761 gaactagaaa atgcaggatt tgaaaccaac gagattcggc aagggtttct atcattaggt
     2821 gggccaatgc aaaacttcaa ggaaatgcta ttggacggta aggtgatttt caacaattcc
     2881 aagctttacc gatggtatct atccaacgtc aagctggtga tggatcgcaa ctcaaactgg
     2941 atgccgtcta agcagtccaa gagtagaaaa atagatggtt ttgcagcaag tttgaacagc
     3001 cacgccgaag tgttgaatat gttggttaat cctgtcggaa ccgggaaagt aacctattac
     3061 tcgatttccg atttaatgaa tatgtaagaa aggtgtggag gaatgagtat tttagatcgt
     3121 ttgcgttctt ttggccgagc gaagccgaaa gcgagcaaac aagagtattt tttgaatgac
     3181 ccgggattga taccgtattt agtcggaaaa gatgaaatat cagaagggat tttttccgta
     3241 attagccgtg tatcgaacgt ttttgcgtct ctccctctca aaatgataga tgtggagttt
     3301 ggccaaccgg acgactgtcc tgcatacaac ttgttgagcg aaggccctcg atattttaca
     3361 aagtttgatt ttttccggga cgtggaagtt ttgagaaact accaagggaa tgcgtatgtg
     3421 cagattttcc gaaatatcaa tggagaagta gcagatatgg cgttagtaaa acctggtgct
     3481 tgccatccag tgattgatat ggatagcggg gagctttact accaagtaac tgcgactgac
     3541 aaaggcagtt acaagcaagt tatctatgta cattacatgg aaatgcttca ctttaaacaa
     3601 ccgaggtttg gcggcttgga aggtacagac cccacaaaag tattaacgaa taccctcgga
     3661 tatgatcgag aagtccgaaa aatctcttta agtcagctta aaggaagtaa tgaagggcta
     3721 aaagttaagt ttgctagcaa tatggatgaa gaagctaaaa aagctacagt taaaaacatt
     3781 gctgattttt atcgacaaaa cggtggacta cttgtggaag aaaacggtgt agaaatcgaa
     3841 cgtttacaac gagagctggt agacagcaag cttttagata ctgataaagt atctcgctcc
     3901 agaatcgcta tggtctacaa tgtgccggag catttcatcg ggaataacca gtcgagttac
     3961 tcctctcagg aacagctcaa tatggaattt ttgacgtaca atctagtacc gaccgttaat
     4021 caatatgaag cggaactaaa taagaaaaca ctatcgagaa ccgaaaaagc aaaaggttat
     4081 cgatataagt ttaatgtcgc aagtttgcta agagctgaca ctcaggcaag gggacaattc
     4141 tatcaaatca tgcgacgagg cggagcatac tcagcgaatg atgtccgaag atttgaggac
     4201 ttgcaaccga taaataaaac cggtatggat gattaccata tttccggaga cctatatcca
     4261 atcgatatgg atccaacatt aagaaaaaca acctcgtcta aaagcgtagc cgaaaacggt
     4321 taggtttttt tagtttgcac cgaagggagg tggaaaaatg aaaaaagtga cgttaagcgg
     4381 cgatgtcgtg gataacgata ccgcgtggct ttatgactgg tttgggatca attgtatctc
     4441 accagggaaa atttctgccg ctcttacaga agcagcgggg gatgaagtag aacttgatat
     4501 ctcatcgaac ggtggggatg tcctagcggc aagcgaaata tataccgcta tccgtgccta
     4561 tccgggaaag gtatccggaa atgttgtgag tattgcagca agcgctgcaa gtgtaatcgc
     4621 ttgcgcttgc gaaccgctta gaatctcacc tacggcacac atcatgattc ataacgcatg
     4681 ggtgaccact agtggcaacg ctgaggaatt aaaagccaat gcagaaatgt taagcagtgt
     4741 ggatgagtct attgttaatg cttacgagat caaaacagga ctcgatcgga aaaaacttgc
     4801 tgatttaatg gcgaaagata cttggttaaa tgctcaaaca gcagtagcag aagggtttgc
     4861 agatgaaatt atgtttgcag aagcaccagt aacggtactc aatgcctctc aaccggttat
     4921 tccaaaaaac gcagtaacta agttgaaaaa tttaatactc aaagcggaag caccgcaaga
     4981 agaaacactc ttacagaaaa aactaaaagc cttaaatgga gggaaaaacg aatgaattta
     5041 gaacaattaa aaaatgcgtg ggtcgaggcg ggaagtaaag tctctgactt aaatgcacaa
     5101 ctcaatgcag cattggttga cgatgaaaaa acagaagaag atgtagtaag tttgcaagca
     5161 caagtaaaag cagcacgggc taaacgggac ggattgaaag agcaagtggc aaatatggaa
     5221 gccgaacaag tcttaaacgt caaaaaagaa ccattagata aaaaagatga aaacttgaaa
     5281 aacaagttta tcaaagactt taaagcgatg gtcaatggtg atcctgctat tatggctact
     5341 ttgacatcta atacggatga atctggtaat gctatcggat tgactattcc tgtagatgtg
     5401 caaacgacta ttcatacttt ggttcgtcgg tttgactctt tgcaagaata cgtaaacgtt
     5461 gaaaaagtga ccactaccag cggttctcgc gtttatgaaa aatggtctga tattacaccg
     5521 ttgactgctt tggatactga agacggtgaa atcccagcaa atgatgatcc tgcactttac
     5581 ttgatcaaat acttgatcaa acgctatgca ggtatttcca cagtaactaa cagcttgcta
     5641 aaagatactg ccgaaaacat tttggcatgg ttgtctaaat ggatcgcgaa aaaagtagtt
     5701 gttactcgca atacaaaaat cttggcagct attgatggaa tcaaagcggc acaaaagaaa
     5761 gatgttacag atgttgatgg aattaaagat atcgtaaacg tccaacttga tccagctatc
     5821 gaagctacat ctatgtttat tacaaaccaa gatggcttca atgttttaga taaagtgaaa
     5881 cgtgctgatg gatcttactt gttacaaaaa gacgtagctt ctgcaactgg atataccttc
     5941 ttaggtaaac caatcaagaa aattgcttct cgtttcttgc caaacaaagg tacgcaagct
     6001 actcctaaat atccactgta cattggtgat ctgaaagaag ccgttacatt gtatgatcgc
     6061 gaaaacatga gcttgctgac aacgaatatt ggtggtggag cttttgaaac agacaccact
     6121 aaagtacgcg tcatcgatcg cttcgatgtg caactagttg atgatgaagc ggttgttttg
     6181 gctactttta caactattgc gaacgagaca ccggcgaaag tttaaggagc tgattcctta
     6241 tgattcttga tcctaaaatg gatttaggcg aaatcaaaaa cgcactaaag attgataccg
     6301 atgatgacga tgtggaagta agccgtgcgg cacaagctgc aattgcatac attagagggg
     6361 ctatcgggaa tgataagccc tctttttata agcaagaaaa tgaaacggtt gatctgatta
     6421 atttagctat cctgcaatta gcagatcatt attacaacgc tcgatcagca accgtgagtg
     6481 ggaacttgcg agagtacgat ttaggtttta caagcctaat cttgcaactc aaagcaagtt
     6541 atttgctttt tgtggaggag gagtagcgta tgccccttat ccaaacagga aatttaaatc
     6601 aacgcatcaa gtttgtccga gatacgacgg ttaaggatga ggacgggcaa gttgtcccga
     6661 cttctacaac cattcttact tgctgggcaa gtgtgcagac acaacgcctg aacgatatta
     6721 agacgtcgat tggtacggct ttggaaggaa cactgacgtt cattatccgc taccaacaaa
     6781 aatcagagct gaccaatgat atgaaagtgc gttggaatgg aaaaacgttt gaaatcatta
     6841 cgattacgaa aggcgagttt gcgaaggact tcacgacaat cattgcaaaa gaggtttcaa
     6901 aatgagtgta gaagtcgatg caaccgaagt gtacaaagcg cttagggaag taaaagcaaa
     6961 cgttcaacga gtggaaagcc cagcacttag aaaagctggg gagtacgctc aagaagagtt
     7021 acgacaaaac acaccttact gggatggaac gaagtcaaac ggtaaacgtg gttcgtatat
     7081 gcaagaacat gctaagaacc atgtggttac aagctcgata aaaaacggat tggtagaagt
     7141 cggctatgac aaagatgttt cttggcggat gcactttatc gagttcggaa caatcaaaca
     7201 acgtccaaaa ggtttcgtac aaaaaacaca aaagcaaatc gaaaaacaag taacacaaat
     7261 cattgctgac gaagtaaaaa ggaggctagg actttgaaaa cggcagtatc acaagtctat
     7321 tcaattctga atagcaatga aaaaacaaag aacattgatt tttacaccaa tagtgttccg
     7381 gaatcagctc aaacagtacc tagccttcca gttggcagaa ttacagagat atccggcaac
     7441 tatgaagatt ttgcaagcaa caatcctttg accattcaat ttaacgtaca ggtagatgta
     7501 tgggtgtcaa ccatgaaaga ggttgatgcc ttttattttg cccttgatga ggttatgagg
     7561 gggaatggtt ggcaatgcgc atacacggaa caaacagatg acgaggactt ggaaggtgca
     7621 aagcggatta tcaaacgata tgtagcaaat atttcactaa attaaaagga gagaaaatag
     7681 atggcaacag taggattcga gagcgtcatt tttggcgtaa aaacaggtgc aggcggcact
     7741 ctaaaagaat tagtagcaga taagtcgaaa ggcggagcga tcgaagctaa aattactgga
     7801 ttaggcgcaa cttctaacac aacatacgct tcaaacgtac cgttcttcat tgcaagtaaa
     7861 ggggtttcgt cgccaaaagt tacgcttgac gtggcagact taatggataa cggcatttac
     7921 agcgaaatca ttggtgctaa aaccgtggat ggtgcaaatg taattggttc agaaactgaa
     7981 gcgccttacg tgtcggtagt catggttaca gcgaacaaag aaggaaaacg cttgttcatg
     8041 ggattgacaa aaggaaaatt cagtcatcca gatatcgaca tgaaaacagc tgaagacaaa
     8101 ggggtagaat tgcaacccga ttccatcgaa ggggaattca tttctgatga acgtggctat
     8161 gtatacttaa cagccgtaga atcagaagga atgaccttac aaaaattcaa ggacttggta
     8221 aataacaaag agggggagta gttaaccctg catctacacc aacgacagat acagggacac
     8281 caaaagaacc agaaccaaaa attgatacac aaggttagcc atttttggct agccttattt
     8341 tttgtaaaaa caaggaggaa aacaaatgat tgaattgcaa ttgaaacttg acggaaagaa
     8401 aaaaacattc aaacaacaag atatttccgc acgtgcaatg cgtgagtgta tcaaatttta
     8461 cgagaaagcg gaaaaagcag acctaactga tttagaagcg attgattcaa tgattgcaat
     8521 tacagcagat attttccaag atccagcagt tacatttgat gctattttag acggtttgac
     8581 tgcgagcgag ttagtaccgg cattagaaag tgtttttgaa caaataaatg aactgggaaa
     8641 caatgaaaaa aagcagacgg cgagcaaaaa gaaataagtt tttctgaagc taggaaagca
     8701 atggatcaaa tctacaaaga tttaatcgaa gcaggttgga cgatgagaga tgtggacgaa
     8761 gccgactatc attatttgtt acaccttttt ggagaagtgg agagtggcga agaatatgta
     8821 gatggtgctg atttcatcaa acaattttta tcggctgaag acttagtaaa acttgaggaa
     8881 ggaggtaaat aatggcagga aaaggacaac cggcaggaaa tatcaagcta gggattagtt
     8941 tagatagcac tagttttggt aacacgctgg acgaaatcaa tgcgaaagtc aaacaagctg
     9001 agtcgaatat gcgtgccaat ctaaaggctt atgattcagc aggacgttca tacgaagcac
     9061 ttagtcaaaa gacgaaagac ttgtctacgg ttatggaagg gcaaaacgcc aaagtaagag
     9121 aattaacaaa gcgccgtgat gaagcgatta gcaagtatgg cgaggaatcg aaacaagttg
     9181 ctaaccttaa cacacagata aacaatgcta ccgcaaaata taatgcttac agtcgccagt
     9241 tgaacgacac aaaaaaagaa ttggtgtatt ccaaaacagc cgtcaatgat ttatctaatg
     9301 aaatcaaaga aaatgaacga caaatgaacg ccgaagtaaa agcgttgaaa gccgctggtg
     9361 atgaatctgg tgcttttgaa gcaaaacaaa aagggctagc caaacaaacg gaattatccg
     9421 agaaagctat cgaagaacag cgcaaagttg tgaaactgat ggctgatgag tttggcgatt
     9481 cagcaaatga aaccgaagat gcaaaaaggg cattagaaaa gttagaacga caaagccaaa
     9541 tatctagcag gcaattagaa gcactcaaaa gctccagcga tcaatcagga aaagaaatag
     9601 aagattttgg cgacaagtcc acaaggtcag ctaggaaact ggacggacta aaagacaaat
     9661 taagctcgct aaaaagcgca ttttcgtttg gtgcagttgc tggattagcg cataacgcta
     9721 ttagcagtgt agtaagtggc gtgcaaggtt tggttggcga agcagtaaac gcatcggatt
     9781 cattgatgaa gttttccaaa accatggagt ttgctaactt tgggaagtca cagatagaaa
     9841 gctcgaaaaa agaaatgaaa gactacgccg ataagacggt ttatggttta gaagaaattc
     9901 tgaacacaac cgcacaattg gcatctaatg ggattcctaa ctatacagaa ctaaccaagg
     9961 cggcaggtaa cttgaatgcc gttgcaggcg gttctagtga tacattcaaa tccgttgcca
    10021 tgatgctaac gcagacggca ggagctggga aactaacaac tgaaaactgg aatcaattag
    10081 cagatgcgat accgggtgct tcaggattgt tacaagacgc tatgttgaaa aacggagctt
    10141 atacaggaaa cttccgtgat gcaatggcgc aaggtcaaat cacttccgac gagttcaacc
    10201 aagcaattgt acagttaggt atgaatgacg gagcagttaa ggcagccact tctacagaca
    10261 cattgagcgg ttcttgggag cagatgaaat ccactgtaat aaatgggcta caaagtatta
    10321 tagaaaaaat aggcgttgaa aatatcactg gtttcatcaa cagagtaaca aaagggattg
    10381 aaaattctat tcctaaaatt actcaattta taggttggtt gagagatatt ggaacgtgga
    10441 tcgttgaaaa tagagagcca ctaacatgga ttgtcggaat cataggcgga attacattag
    10501 cagtaaaagc attgaacgta gcaagtatgt tgctggcaat tactggcgga acattggcag
    10561 ccccttttgt ggcgattggt gtagcattag gcgcactagc aggtgctttg gtgatagctt
    10621 atacaaaatc tgaaacattt agaaatatag tcaatgcggc ttttacagct gtgaaaaacg
    10681 tagttatgag cgttatcaat aatttggtgg aatactacaa aatgttgtgg agcgtgttgc
    10741 agtggctttg ggaaaaaata aaagaatggg cttcatggat tggcaataaa ttcattgaaa
    10801 tgaagaacag cgttgtgaat acggttcaga acctatggaa tggcgtgaaa aacttcttca
    10861 gcaatggcgt tggagatacg tggaataagg tagtcggttg ggtaaaaaac attttcaaca
    10921 aagcaactga attgaagaac aacgtttctg atgtaatcgg taacctgtgg aatggtatca
    10981 aagacacatt ccgtagaggt atcgatacgg tattcaattg gttttcagaa ctaccaacga
    11041 agatgaagaa tgccattatt ggcggtaaaa acgccattgt tgatgcgttc aaaagtattt
    11101 tcaacgcagc acttaaagcg ataggtaaac cagttaacgc aatcatccat ggagcttcat
    11161 gggtactaga aaaattgggc gcagaacctc tacaagaatg ggatgtacca caatacgcta
    11221 caggtacacc agcaggtggg cacccaatca atggtccaat gatggttaat gatggacgtg
    11281 gagcagaaac agttatcaca ccagatggta gagccttcat tcctaaagga cgcaatgttg
    11341 ttctaaacgc accaaaagga acgcatgtct tgacagcaga agagaccgcg caacttcaag
    11401 gttctaaagc tcctaagtat cgttacaaaa aaggtactaa cttctttggt aacatgtggg
    11461 atagtgtgaa aaaggttgct ggtaatgtag gtcacacaat taaaaacgta gtaggtgacg
    11521 tgtgggactt tatttcagac ccgggagcgt tagctagaaa agtacttggg gggttagatg
    11581 tattaggtgg attgacaaag tatccattag aagtaggtaa aggcatccta tctaaagcaa
    11641 caagtgcact gactgaaaaa atcactgggt tgttctcatc tggtaactta gatacctccg
    11701 taggaacaaa tggcgtctat aaatatttgg ctgatgttgc taagtctgtg atgaagaaat
    11761 tcccaggatt tgtggcaact agtgggtata gaccaggtga cccttattca catggtaaac
    11821 gtaatgccat tgatattgca ttaccaggcg tcacaggagg ctcacctaga tacacagaag
    11881 cagcaaacta cgcttttgac aaattcgctt ccaaaattgg ttacgtaatc actaatggga
    11941 aagttcgtga ccgttcagga caatcaggtc aaccagcaac tggtgcatgg gagccatggc
    12001 ccgatggaga tcactatgat catgtgcatt taaacggtgt gaaagaccca caaaacactc
    12061 aaatttcagg agatagcgtg ggaggcagtg gggtagaaag atggcgcaat gtagcaatta
    12121 gagcgttgaa aatgaccggt caatacagta ctgcaaactt aaatgcatta ctaaatcaaa
    12181 tgcgtacaga gtcaaatggt aatcctaatg cagttaacaa ttgggatatt aacgccaaaa
    12241 atggaacacc atcaaaaggg ttgctccaag tgattgaccc aacattcaga cagtatgcaa
    12301 tgccaggatt caacagcaat atttttgacc cactatctaa catcttagct tcaatcagat
    12361 acgcactatc aagatatggc tcactaacaa atgcctatcg tggagttggt tacgcaaacg
    12421 gtggaattgt aaaccaacat caaattgcgg aaatcgcaga aggaaacaag ccagaaatta
    12481 ttattccgtt agataaggct aaacgatcaa gagcgatgca attattgtct atcgcaatgg
    12541 acaaactagg agtttctcct aaaacttatg gaaatgcgac aactgtttcc agtgattacg
    12601 aaatcctaga agccattgaa aaacaggcgg caacaacgaa tcagctgtta tcgttattgc
    12661 tggcattttt caaaggaaat agccgaactg atagagattt agctttagat attcagaaga
    12721 tcttggttag gaggatgtag atgcgaactg tattactgag aaatagaata aacgaagaaa
    12781 ttgatttgtc cacagaagac tattttgcta ctgggttgag taatatgggg tttgaagtaa
    12841 aaaaagaaca tgtgggacag tgggggaatt tcagagaaag cagtgagagc gttgaaatat
    12901 ctgaatttca gtcatctgta atcatttctg tgcatgggtt tcgagaaaaa gaactgtaca
    12961 attcacttgt gcagttccta tcggaaggtc cgtttgaact ggaatttgct tttgacggcg
    13021 aaacaatggt aagaagatgc agtctaaaat ctttaagtaa gactgaaatc gatccgaaaa
    13081 catcgttact aacagacact ttagaactat atttcacatc aaactggtat tccgtaaaac
    13141 gcgaaaaatt aattcagcga ccgaatgtag tgaaaacacg tggtaaggtt tttccgtata
    13201 aaagatctta tatctacact caaaacttgt gggagaaaaa aggtgtattc aaattcaata
    13261 ataattctgt atacctaacg aatagcaagg aacggatgtc cccgctaaaa attcgtgtga
    13321 ttgggaagtg ttcaaatccg tattgggaag taatccaaaa ctcacaaatc atcgcaacgg
    13381 atggatactt catagatatg actgaaacac agactctaga agtatcaagc ctttttgaag
    13441 atacaacggc gattttaaaa gatattgcag gggtagaatc ttctgtctac caacaacagg
    13501 attatacaaa aactaatttt gttcaggccc caactggaga attcagcatt gtgtttcatg
    13561 ttgggggggc agacgtagag attgagttat acgaggagcg tgatctgttt tgattttagc
    13621 agtcacgctt tttcatcgtg atttaatgct ttataacgaa catttattct ctaacagttt
    13681 tgaatttggt gtggacgaga tcaacgaaga ggctagtagc tttacgatgg ataagtacgt
    13741 tcctgtaaaa acaggcgatt ttctactagc aaaatatatt cctagtggaa aatttgcata
    13801 ttttggtgta attacgtcgc aggaagacga aaaaatcagt tgtaaaagct tacttagttt
    13861 agctgatagt gagataccga ctgcacgtgt gtcaggagat aactacgaag agcatatccg
    13921 gcggttgatt gaatactatt tgctgaatga tccaacgaaa caactaaaag atattttaga
    13981 cgtcaaagca gaaagtgcga cctctcattc gtatcaagct accgatacga ataaacacaa
    14041 gttaagtgcg tatattctca atggtttcaa aaaatacaac gtaaaatggt atttcaaggg
    14101 aattcaaaac agaaaaattt atacaggcat acgtgctgta aatgaatcaa tttacattaa
    14161 agacaattct tctgaattta gcgattggga tgtgtttgtt caggcgccgg gcgctggaaa
    14221 cgagaacaag ctattaatcg ttgataaagc aatgaaagat atagagaaac cgataatact
    14281 gtcaacatgg tatttggacg aagaaaacaa tttgacacaa gatggatcga aagaaaatat
    14341 cacgaaacca actgtcaatt tggttaatat ctacgatcaa accgcagaag ataaagcatc
    14401 ctacgaagat gtggcaaaat cagagttgaa aggcaatacg tattcgcatg aaatcaaagt
    14461 gaacgttgta agaaatgcaa aaaatttgaa tgtcgaaacg attgaaacag ggatgtttgc
    14521 cacgatttct tataaaggaa agatatacaa gtcggttttg acagcttggc gaatatcaag
    14581 tgataaggag tttgtggaat tgactttcgg aaacataaga agtcgtttta tggattattt
    14641 tgaagataat gggggataaa aaatggttag caatgtggat ggatatcaat ttgaaaacgt
    14701 gaaagtaagc gcagaaaatg atgctagact ttatcacgtt ttatataatc ggaaaaatca
    14761 ggttattgat ggttacgatc agtctatgaa tttatcttca agcggattaa cagtaaaagt
    14821 tgctgcagga gcagcgatta ttcaaggtcg tatggtcgtt gttcgacaag aagaaagtat
    14881 aacagttcca gcaaactcaa gtggttatat agcattaaca gtggatttga cacaagaagt
    14941 tatacctgga tctattcttc cagaatcgga agaatatgaa tggactaata atcaagtcaa
    15001 gctagaattt ataacaaaag ttataaaagg taatttaaac aatggtgata aggtctataa
    15061 tttaccacta tgctcagtta attctactgg atcaactgtt tcaatctcaa agatatcgga
    15121 tagttacgag ctgactctct ctaaaggaga aattttgtgg agggggactg cgttaatgca
    15181 tgatactcaa actgtccaac cttcaaaaaa aatttggcag acagtttcag gttttttgtt
    15241 agtatggctc ccatacgaaa acgggcaagc aattgaggat agatatgtaa ctacgccttt
    15301 ttataaggag cgtgtaactt ttactaatgt tttaggagaa attgtttcag gatttgatga
    15361 ctatcacaaa aagtggttta gtaaacgaat aaactataat tcgaatacta atatatttac
    15421 aggtgcagca agcaatgcaa gtggagataa cgcaaatatg gtgcttaggt atatagtttc
    15481 tttttagtta ggaggtatgg aagagtggca aatttagaaa ttaaattatc tgcaaataag
    15541 agacagcctt atctacgtca ccgtgttgtt ggtagagttg gtgatggggg gctcacaaca
    15601 atcaatgtac aacttcttga ggaagatgaa attacacctt ttgtaattaa tctaaacggt
    15661 actttgaaat ttgtgggcga agtttcaaac ggtaactata ccgagggaga accagaaata
    15721 atcgattcga ctaatgggtt aattagttac acgttcacta agtcaaattt cagcacgagt
    15781 catcaattca aacaagcata ttttgaatat gtagatccta acggcaaaaa agtaactttt
    15841 cagaacttca tcatagacgt gttagaacga gtggatatta attcggagca agcgaaatac
    15901 tatatttctt cattggaaaa attacagagt gaaatgcaaa ccactttcaa tcagttcatt
    15961 agtgataaac aggtccaata cgatcaaatc tactcgaaat ataacgaatt agtaagattg
    16021 ataaatgaat cagataagca agtaaatgat cgtattgatc aaaccaatca gcaaatcggc
    16081 gatctcggca agctgaaaaa gatgtacagt aacagcatcg actttggggg ctatgattat
    16141 tcggggaatc cgaatttgtt aagtaagcta tcatacgact taattgaaaa tcaaaatact
    16201 tcagctggaa cactttctaa gggtgaaaac tcgtttaaat ataataagat atcagctgaa
    16261 gtggaaggtg gagtagagtt atattataaa cgaagaggta tagctaactg gttaccctct
    16321 aataaaacgc ttgtaatgac tgttaagctt agagctggag cggactatag tccagttgac
    16381 ggaaaactta tactgattag atataggtat gttgacagtg gaactggcaa gattgtttta
    16441 gacttaccta ttaacagtaa ttcgataact caggaatgga aagagtttag tattactgga
    16501 actactccaa catttagccc acaagcatac catccttgga tacaatttag ggctcaagat
    16561 ggggtacttg gggaaataga aatgagctat gacatcaaaa tcgaagaagg ctctacagct
    16621 acaccatatc agcctaactt acttgatgac tcttactggc taggtaaaac accgttgggt
    16681 gagaatttga taacgaatgc caagttccca attataacac gaagcaatcc tatttctggt
    16741 tttgatattt cagaagaatt aataataggt gaaacttata cggtatcttt aaaagggact
    16801 aagccagcta ctaaagaatt ccacttatac tacggagaag caaattacca gcagttgcag
    16861 tatcaggcaa ctttacttcc tgtggaagga ttaacagatg tgtggagtgc cacttttaca
    16921 gccagaaata ctagtgaaac gacaaattta cttagagtag cgttatggca aaaacctaat
    16981 tctgcaacat atggtactgt tcaaattgac tggctcaaga ttgaaaaagg cgacacacgc
    17041 acaccaaata tcagtcagtt taaatacttt ggtgaaggct tgaaagacag taacaatccg
    17101 aacgactaca gctgggatgt cacaccagag tatactgaaa aaagcttgaa taatacggtt
    17161 agtctgactg aaccgcaatc catcgaagga ttgaaaaatt tcgaagatgg tattcaatca
    17221 aaaggaaaat ctgtattgac atcagacgac aacaaatatg aagtcgtaac cttaacagtt
    17281 acaaacggga ataccggatc agcaaagctt tatcgtgaag gaaaaaccgt cactatttat
    17341 ttttttgcgt tgaatgggaa aagcagtggt ggaaatgatt caacgatact aacaattcca
    17401 gaaggctatc ggccaccaat tagttttgag caactggttg gctcgataga ccgttctact
    17461 ttgaacagtg ctcagttatc tattggtgca gatggagcca ttaaatggcg aagaaactca
    17521 agttatggat cggattatac ctttgcaatt acttacacga tttagaaagg cgtgaatcga
    17581 tatgaaggca gcatatagac caattgaacc ttacggattc gagcaaatca ttgtgaatga
    17641 tgaagaacat ttaccggaag aatgcacaga agtcgaacca ccgattccaa attggaaacc
    17701 gaaattcaat tactgggagg gaaataaatg aaaaacattt ggaaatatgg ccgtactggc
    17761 ggagagtatg caggaaaagt attggacgac atgcttgtat ccgttcctta cacagatcag
    17821 ccaccgctcg aaggggttcg ttcagatggc gaaccgctaa cgattgctga tcagatgttt
    17881 gatcctaaat tgaaccaatg gattatttta gcgaacgcgt tagatcacaa cgatttaaac
    17941 aatctcaaag cgatgtacga ggctcttgaa catgaaaacg gcaacctaaa acagctaaat
    18001 gccaaactca tgctaagcga tgtagcgatt aaacaggaaa atactgcatt gaaagaaaaa
    18061 gctgacagtt tagcacaaat caattcaaaa atgatgcttg cttcgttaca aaatagcaaa
    18121 gacatttcag aaattaaaga gcaactaaat ccagcttcaa agggaggtga gtagtatgtt
    18181 tagttttagc gatgtgaaaa tgatgtatga ttggggctgt tttactgacg atcaagttcg
    18241 tctattcgtt ccactatgta tcacagatga agaagcagat agaattatta gcaaagaaga
    18301 gagcgcatct taagtgatgc gtttttttgt tggaaagttg gtggaacatg aaagaagaag
    18361 cgctccaaga cgttgtggag agattagtaa gaattgaaac aaaattagac aactacgaat
    18421 cacttagaga aaaagctgat agtgcaaaag atttggcaga caaagcctac tcagtagcgc
    18481 taaacaacgc agaagatatc aaagaaatga aagccaataa taaatggtcg tggggttaca
    18541 tgatcggttt aggcattacg atcattggct atttcttgac taaattgtaa aggagttaag
    18601 aagaaatgat tttacccgat aagtattatc aagtcattaa atggacggtt ttaacagtat
    18661 taccagctgc atctgtttta gtagccacgt taggaaaagc gtatggatgg aatggaacag
    18721 atatgacagt actcactatc aatgcagtag caacattttt aggcgttatc actggtgtgt
    18781 ctgcatataa cttaaaaaaa taggaggaaa aaaatgaaga agaaaatcat tttatcattg
    18841 agcctaataa tggctctttt tttattgcca attaacgggt tcgcctatac gatcaacaat
    18901 gaatttaatt taggtgtaaa tgaaggtagc tcacaagtag caaataatca gtatatttta
    18961 ctgcatgaaa cggctaatga aacagcgaca ggacgcaatg aagcacagta tatgcaacgt
    19021 tcatggacta gtgcttatac tgcttacatt gtgggagacg gcggaattgt ttatcaagtc
    19081 ggtcaacctg gttatgtaca gtacggtgct ggttcgtatg ctaatgcaaa tagtcctgtg
    19141 cagattgagt tacaacacac acatgataaa gcaacttttg aaaagaacta taaagcatac
    19201 gttgaattgg ctagagattc agcaatgaaa tatggtattc cattaacatt agacactcct
    19261 tataaccaac caggaatcaa atcgcattta tgggtaacgc aaaatatttg gggcgatcat
    19321 acagatcctt acggttatct ttctgaaatg ggcataagta aagaaaaatt agcatatgat
    19381 ttagctcatg gatttaccga tgaaaatcca actacttcag atgataaacc agtcattgat
    19441 ccaactagag caggtgctgc aaatcctacg ctgacagatg gaacaaatta cgcccacatt
    19501 gatcagttcg gagaaatcga aaacgcaaac ttgcatgtag caggatggca tattgctaac
    19561 tataaatacg agtatatttt cattatggat tacaatactg gaaaagaatt agctcgagta
    19621 aaagctgatg ggatttatag accagacgta aatcaagctt ataatacttc tggaaatgtt
    19681 ggttatcatg tatctttcaa tatgcgtaat tttcctagta agaaagtcta tgtaatgatg
    19741 cgggcaacga atgatccaga gggaaacact aaaggcggtg cgcaagattt ccatgacaaa
    19801 cgttggtatt taaatattcc taaacgataa aaatagctcc tcgttgagga gcagtacata
    19861 actatattga caactataaa aattattcga taaaatagtg atgttatcgc atatcttcac
    19921 tatcacccat aaatagtcac actccaagct atgcgataac aggtttgttg ccacacattc
    19981 tactggttga ttgtttatgg ctttatgtgg caacaaccag tacccttagc tcagttggtc
    20041 agagcagacg gctcataacc gtccggtcgt aggttcgagt cctacagggt acattaacgt
    20101 agccatttga atcgttctgt gttagaattt ttttgaagag tattatacaa gctaaagctt
    20161 ttcttcattg ccactcaaat gagtggcttt tttatgtatc cttttatgga ttaatgaaag
    20221 gatgtttcac atagttatac ttctgtatat ttgaaaagtt ttactttgat ttttaaatag
    20281 aaagacattt gggttaaatt gtgagataat aataaagaag agtttaaagc gcaccccaaa
    20341 ccacttcccc ataagtgtgt tacgctttaa actcttttat atttgaagcc attaaaaagc
    20401 ataccatatt tttgaaaaaa agtgagaaaa aaggcttaca attggagtgg tagttaatta
    20461 gtgacttatt tttgatttta tagcactgat actataaaat atagatatca tcatattaca
    20521 caatcttaat actaacttaa aaaatatctc ctttcacaag tatggtgata aaattcgttc
    20581 cgggctacct ttttaggtag cctactttaa tctttatacc tttctggatc aacgaaagta
    20641 tactttatat agtcataacg ccgatgatcg ctacgtgcgt ctggcacgtc agtc
//
LOCUS       DAFEKH010000049        20683 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.051, whole genome shotgun sequence.
ACCESSION   DAFEKH010000049
VERSION     DAFEKH010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20683
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.051"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(433..1746)
                     /locus_tag="LP386_002085"
     CDS             complement(433..1746)
                     /locus_tag="LP386_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBL1919316.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCILMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLLGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFMGFMWILNVK"
     gene            complement(1991..2215)
                     /locus_tag="LP386_002086"
     CDS             complement(1991..2215)
                     /locus_tag="LP386_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919317.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(2235..2657)
                     /locus_tag="LP386_002087"
     CDS             complement(2235..2657)
                     /locus_tag="LP386_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HBL1919318.1"
                     /translation="MESVYRQERKSNRKKGQTMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGVLTFNFSDPEGNYFVIGKAESSD"
     gene            complement(2799..3509)
                     /locus_tag="LP386_002088"
     CDS             complement(2799..3509)
                     /locus_tag="LP386_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919319.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGDESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(3527..4023)
                     /locus_tag="LP386_002089"
                     /pseudo
     CDS             complement(3527..4023)
                     /locus_tag="LP386_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(4060..4512)
                     /locus_tag="LP386_002090"
     CDS             complement(4060..4512)
                     /locus_tag="LP386_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL1919320.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(4647..5252)
                     /locus_tag="LP386_002091"
     CDS             complement(4647..5252)
                     /locus_tag="LP386_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBL1919321.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(5702..6322)
                     /locus_tag="LP386_002092"
     CDS             complement(5702..6322)
                     /locus_tag="LP386_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBL1919322.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(6324..7193)
                     /locus_tag="LP386_002093"
     CDS             complement(6324..7193)
                     /locus_tag="LP386_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HBL1919323.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANKAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(7216..7623)
                     /locus_tag="LP386_002094"
     CDS             complement(7216..7623)
                     /locus_tag="LP386_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBL1919324.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDRHKLAELYEQVGLKFSELHENDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(7642..8931)
                     /locus_tag="LP386_002095"
     CDS             complement(7642..8931)
                     /locus_tag="LP386_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL1919325.1"
                     /translation="MSVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     ILLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFINATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(8958..9260)
                     /locus_tag="LP386_002096"
     CDS             complement(8958..9260)
                     /locus_tag="LP386_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1919326.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(9285..11378)
                     /locus_tag="LP386_002097"
     CDS             complement(9285..11378)
                     /locus_tag="LP386_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBL1919327.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLEEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(11867..12595)
                     /locus_tag="LP386_002098"
     CDS             complement(11867..12595)
                     /locus_tag="LP386_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HBL1919328.1"
                     /translation="MGLCLFALPTQGFAVAGGHGGGTSSGRSSGRGSFGGRSYGGSYF
                     GSRSYGRDSYGYYGPSTGPSSYEQTGFLALAVLSVGGVSAFSIVKNKRQKKRLKSEIL
                     SRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFAEHQKVLQKNKAD
                     GVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLISGSKTQRQYFSQ
                     IWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(12741..15362)
                     /locus_tag="LP386_002099"
                     /pseudo
     CDS             complement(12741..15362)
                     /locus_tag="LP386_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298916.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
     gene            complement(15476..16807)
                     /locus_tag="LP386_002100"
     CDS             complement(15476..16807)
                     /locus_tag="LP386_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1919329.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRVMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKANFGQLNELVPFGFAGMIASFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKNAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQSGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFVGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQLIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(16773..18251)
                     /locus_tag="LP386_002101"
     CDS             complement(16773..18251)
                     /locus_tag="LP386_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1919330.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLKNPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(18556..20391)
                     /gene="tdc"
                     /locus_tag="LP386_002102"
     CDS             complement(18556..20391)
                     /gene="tdc"
                     /locus_tag="LP386_002102"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBL1919331.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEQVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     EQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKEIAKAMEKKLNEIIQ"
BASE COUNT         6000 a         4433 c         3465 g         6785 t
ORIGIN      
        1 tggatgtttc tattttttgc ttaatcattt attttagtct ctctcactaa aaattgtaac
       61 gctttcaaat agctattgca ccttgttatc ggtaacagaa taaaacaaaa aaacagctga
      121 ggaaattccc tcaactgttt tttgaaagga ttgatttatt cagggaagaa tgctgatttc
      181 acaacttctt tataaacggt gttcactcag ctgtccctcg gtattagctc aaaaaacggc
      241 aaaatataag aaactatttt tttcgttttt ttctctaata ctcaggccag aacactgatt
      301 tcacaacctc tttataaacg gtgttcactc agctgtccct tggtattagc tcaaaaaaag
      361 gcaaaatatg aggaactatt ttttcgtttt tttctctaat actcaggcca gaacactgat
      421 ttcacaacct ctttatttca cattcaatat ccacatgaat cccatgaata caaagaacag
      481 accatacatg atgggagata cttcttttcc tcttttagct gctaacatgg taattggata
      541 gaagataaaa cctaatgcaa tcccatctga aatactataa gtcaaaggca tgccgatcaa
      601 gatcaagaat gaagggatcg caatctctaa gtttccccat tcgatttgtc gcaaagattg
      661 tgccatcaat actcctacca taatcaatgc tggtgcagtt acttgtgaag taacaactga
      721 tagtaatgga gaaaagaaca agcctaacaa gaagaaaatc cctgtagtaa tagctgtgat
      781 acctgaacgt cctccaacgg cgataccagc tgatgattct acaaatgcac caacaggaga
      841 agtacctaat aaggaacccg caagcatagc tgttgaatca gaagctaaag ctttccctac
      901 acgaggcatc ttgttgtctt tcatgaaacc tgcttggttt gctaatccaa ctaaagttcc
      961 tgctgtatca aagaaagtca caagcaagaa tgtcagcact acgacccaca tttgaagaga
     1021 attgatgtcc cctacatgtt ttaatgcaac taaaaatgtt ggtttcaaac ttggtgctgc
     1081 ggcaacaatt tcagaaggca ttggaatcaa acctgtgacc agacctaaaa tcgttgtagc
     1141 tgccatcccg atgaagatgc cacctggtac acgccgaaca agcaagatag cagttacgac
     1201 taatccaaaa atcgtcaacc aagtagaacc aacgttgagt gatcctaatc ctactaatgt
     1261 agattcattc gaaacgatga tcccaccttc gctcagacca aggaaagcaa taaatagacc
     1321 gataccgcca gaaatcgcat atttcaaatc tgctgggatc gcatcaatga tcatttcccg
     1381 cagcttgaag attgtgatca aaataaaaat caaagaagca acgaatacgc cggctaatgc
     1441 tgtttcccat ggaatcccca ttcctaaaca aacagaataa gcaaaaaaag cattgatccc
     1501 aagagcaggt gccgttccaa ttggataacg ggctaatacc cccattaaaa tacagccgat
     1561 cgcactggct aatgcagtcg cagtaaacac tgctccttca tccattccag aagcacctaa
     1621 tacagttgga tttacaaata agatataagc cattgagata aatgttgtaa atcctgccag
     1681 tacctcacgt tttaccgtgg tgttcaattt ttctatttcg aagtaggaaa gtattttttc
     1741 cttcatcttc catcccccta aatccgaaca ttataaataa agtccgttaa aatttcgatt
     1801 tattaataaa acaacgtgtt ttatcatata ctaaaacaaa acataagtaa acaaaaaatt
     1861 cggattttaa gcaaaatccg aacgttccat ctgattaaat ccctttatct caaagttcat
     1921 gaacattcac tttggattac aagaatttct ttattgtgtt aataaagttt cttcattcta
     1981 gtctcaaaaa tcaatagtgt gatttgattt taccatttcg tttctgttct tctttgatga
     2041 attcttttgt atcgacagga ttcagattat ttagtccgcc aaaacctgta tcgaccattt
     2101 ttccccagcc ttttgtcttc ttttttcctg atttgagatt ctttgctcga agcttctcac
     2161 tatgttttgc tcgccgatac ttcaaataac cttctaatct tcccattaga tccactgttt
     2221 ctcctccttt ttattcaatc agacgactca gcttttccta taacaaaata attgccttca
     2281 gggtccgaaa aattgaaagt caagacgcca ttgttgtctg tgatttctcc tggttcttcc
     2341 atgttctcgt agatagtttc aaattcatcc gtaaaaaata ctaaagaagg cggtggtcct
     2401 aatacctctg gtgaaaactt ctgcacaaat acttttggga atacgcctaa ttctaattct
     2461 tttgagatgc tgagtacaat actcttaaat tcttctggca attcgattgt ttcagaaatt
     2521 tctgcaccaa ttttttctac aaagaatcgg caaatcatct ctacgtcatt gacataaagc
     2581 atcacacgtg ttttttgtat catcgtttga cccttctttc tatttgattt tctttcctgt
     2641 ctataaactg attccattat atcacgaaag cgcaaacacc ttgtgtttga tactattcaa
     2701 gaaaaataaa gcaatagttt ctaggattgc tttcctccac aaactttttt tacaaaaaaa
     2761 aaacggcaat gaatgccgct cttcttattt cgattctttt ataattctgc ttctgattca
     2821 tctttggtta gtgtgtgtct aacactagtt acgccaaatg tttgatcgat tttttccttc
     2881 aacgcttcga ttgcctgtgc gccacgtgcc gcttgttcag cattgatgga ttcaatgacc
     2941 agcaccgctg cttgtgtttc ttccgtcagc atcgttcttt gggcttcacg ccagttgaga
     3001 cagcgacaga tcgctccttg ttcatcatag tagatgattt cttccggaag tgccggagca
     3061 tcggaatctg cacctaaagg caggaatgat tcgtcacctt gggcttttcc taaatgcaga
     3121 tttcctgcga tcttttcgat atcttctccg ccgcaaggta cgccaaaaga caaggaaata
     3181 ctattataga tatctacaag cggattgatt gggaaaaatt cccgttcttg atttgcacgt
     3241 ttcagtaaag cttcaataga agaacgtgca ccttttttag tcttgaatgt ggtaaatgcc
     3301 tgacgccact gagcaatgac ttcgttttgg ctgaatgttt cttctgtaag gtaatttctt
     3361 gcttcttttg ctgcctcatt caataattga tgatacgttt cttcactttc ttttgttacg
     3421 tggttatcga taccatttac ggataagatt tcgatggttg cttcaggaaa tacttcccag
     3481 aaattggtat ccactattac ttttttcatc tgttcacacc tcttgattag aataattgct
     3541 tgatgaatag atagtctgtt tggggatcat ctcccatata aaaaacatgt tcgctgtatt
     3601 tgataaatcc ttttttacga taaaaagcga gcgcaacatc gttgtgttcc caaacaccga
     3661 gccaaatggc tgttttttgc ttttcttttg ctttttcaat agctgtatct agtaaaaatg
     3721 taccgatacc ttgatgttta aatttttttc gtacatagat tcgctcgatt tctaaaaaat
     3781 gatcagccat ttcctcagat tgactcgttc ctgtatttag tttcaggtaa cccgcaggct
     3841 cttgatcgat actcactagg aaaaaatctg tttctttatc ttttagctct tctgtaagtt
     3901 tttctagtgc ataagcttgt gtcaagtaat cagctaaatg ctccggtaat tatcttttcc
     3961 aaatgtatct gtaaatgttt cgatactaat ttgttgtagt aagtctacat ctgaaggcgt
     4021 catttttcga atttcgtatt tattcacggc ttcttccttt caatagatcc ttttattgcc
     4081 ttttttgaca aaattccaat cttcgctaac attcttgcat actttattta aaagatattc
     4141 caattgtttt gcttcttcgt cagaaagacc atttaatgcg actgcattgg agtagttgtt
     4201 ttctcgaatg atgaaaggat agatttctgc tcctttttta gtcggataga gtttcttgat
     4261 ttttttattt tctttatctt ccaaacgttc gatcatccca ttggattcta atttcttgat
     4321 tgctcgggca gtcgttgtac gatctacttt gatcatttct gctagttttt cttggatgat
     4381 tccaggattt tcgcaaatac gtactaaata aagatactgt cctcttgtta aatcgacttc
     4441 tttgaattcg atattgctaa tagagtctag cgctcgggca atcattccga tgtctcgaag
     4501 gatttcagcc atttcatccc acctttattt tgtttgtaag actagtttac ctctttttgt
     4561 tgcaaatgca actattttta ataaaaaaat caagttcttt tttaataact agtaaagtat
     4621 attcttttct tcttttacga aaaagctcaa tcacaataga tctggttttt gttttctaaa
     4681 ataagtaact gtttcttcgt tgttcgcttt tctgatagct ttggcaactc ttctatacta
     4741 aaaaatccca tgttggaagt ttcattattc tcaataaact tggcctcttc accgtggatc
     4801 gcacaagcaa aaacaagttt ataatactga aaaagctgtg gaatatcttt ttgtttattc
     4861 gtatcaaaaa ctgctcgcaa ctgagtagtt tctactgtta atcctgtttc ttcatagact
     4921 tctttacgca cattttcttc aggagacaat cctatttcag caaatccacc aggaagtgac
     4981 cattctttcg tccgtttatc ttcgattagt aggaccttgc catctttttt gatataggca
     5041 cgaacatcta cttttggtgt tggatgtcct tctccaatcg ttgtgagcgc ttttatttct
     5101 tcgaaagttt cttttcctat ttcactgatc agttccaatg aaatcgtccg gatctcctca
     5161 aaacgctctt tatcaaatac atcttttcca taatatagac cagcttgaga aagtgcgagt
     5221 agtcttttgt attgagccaa cttcttgttc attctcttcc cttctttttt agcaaatgta
     5281 tgactatgta atcaagtata gaagactggt ttaattacgg caaataaata taatgaaatc
     5341 tgcaataaat aaaagaatgt taaaaaactc gagaacaaaa gacattcgac ttctctgggg
     5401 ctgtgaataa atggcgttca aaagcttgca tctgcggtaa taagccccat caaacgaaaa
     5461 atatgacgag ctattcttgt ctggctgttc ttattaattg aggcaggaca gctttttcac
     5521 aacctcccca ctaaacggtg ttctcctacc aactcctcgg tcacaagtca caatattcat
     5581 caaacatgag aagctgtttc tttgaaattg ctccttgtga ctcggagctg aacgacaggc
     5641 tcacgacctc tcggtaaacg gtgttcaaaa gccaattttt cgatattaag ccatttcttt
     5701 gttacttatt gtcattgatt tctttttcta atttatccaa tagtggagtg taatccactt
     5761 gagtatagtc tgttacatca aattcatata gtgttcctaa ctggaatttg tcatattttc
     5821 ggtcggcgat gatctttttg aatgcttctt tcgtaatatg attggtccct ttcgttcgat
     5881 cttccaatac gtcaccatag tgataatgat ccatgatata gctcaaatga cgatctgatt
     5941 cacgatcacg tttgtaccga cgttgccata acacttcaaa gtctgctgtt aggcgaatcg
     6001 tgatcacctg atatccgtat ctatctgcta attcttggag tcgtgctttt tgcttatcac
     6061 taaaaggata ctcggacaca atcactttct ttcctgcttc catatacaaa tcaagtgctt
     6121 tgtaatagaa aggataaact ttcgtccttt cttgttccgc ccgttcttcc aaattgttaa
     6181 acccgatgga ttctgcatag tattccttga tttcatcgag cgtgatggca tacatatctg
     6241 gaaatcgttc ccgtagttta ttcataagat atgtttttcc tgtaccagga ctaccagcca
     6301 gaagaatgaa atactttttc atctcattta tttcctaagt taattggact ttccaagttc
     6361 ataaacagtc caatcttatg cttgacaatt tcttttactg ctttatttgc tggaatcaca
     6421 ttatggcgaa gagacttgtt gatttctgtt tcactaaagg tttctttagc tactttcgtc
     6481 cagttgacta aaagctccgt tccaacattg aatttgcgga tcccgttatt gatcaattca
     6541 ggataatctt cttctttcac acctgttcct ccatggataa ctagggggac atcaactact
     6601 gcatcgattt ctttcagcaa gggaatgttt acttctgttt ttgatttgaa ttgtccatga
     6661 ttcgtaccga tagcaatagc taatgcatcc acgcctgtag cttctacaaa tttcactgcg
     6721 tcttccggtc ttgtatatac cttgtcattt tcagcgacat ggattccttc ttctgtaccg
     6781 ccgattgttc caagttctcc ttctacggaa acaccgtgcg catgggcata ttctactact
     6841 gcttttgtct tcaagatatt ttctttgaaa ggtagatggg acccgtcata catgacagaa
     6901 gtatatccgc tatcgattgc ttctttgata tcatcaaagt ctcgggcgtg gtctaagtgt
     6961 aagactgcat caaccatttc ttcttctgca atagctgtca ttacattgac taacacatgc
     7021 atgccgatat atttagcggt atcgacactt gtttgaataa tgattggcga acccatttct
     7081 tttgctgcgc ctagcatggc aggaagcatt tctaggttat gcgtattaaa agctccaact
     7141 gtaaaattca actcttctgc tgtttttgtt acttctttca atgttgtata catcttttat
     7201 tgccacctta tctttttatt tgtttccttt gatcgttact tgttttgcaa tttgtcgcat
     7261 ctcatccatt ttgcccatgt agtaatcgat cccttgatca tcaccagcac gagcagcatc
     7321 tgcacgcttc tggttataga ggctcatcag ttttttatac ccatctccga tcgtctgttt
     7381 attttccaag ctcttttcta aatattggat ggcttgatcg ttctcatgca attcagaaaa
     7441 tttaagtcca acttgttcat aaagttccgc taatttatgc ctatcttggg tagtggaaat
     7501 ctcttgtttc aattgtgtaa tctctgattg aatcttttcg gtcgcttctg gcgatagggc
     7561 tttttcttct tttgccagaa cttttttcgg ttctttttct tttttcttaa aaaatccaaa
     7621 catcattttc cctactttca attaaaacgc tttcaaaact gggcttaaga tccaggcata
     7681 taagagtgct gcggctactg tatctacatc ggttgctgta gcattgatga atcccatcga
     7741 attaaagatc gttactagca aagcgggcaa taatgtaata aagaaaccat gagcaatacc
     7801 gccaatgatc gctcctcggc gtccgccaac tgcgttgcca aatatccctg ctgtccctcc
     7861 ggcaaagaaa ttggttagca taccaggtaa aatcatcgct aagccgaaca tgggcaaagt
     7921 aaacatggca ataatcgtac caatcgttgt cgtaatgaaa cctaaaatga cggcatttgg
     7981 gctataagga aagaaaactg gacaatctaa ggcagggatc gcatcaggaa ctaatttcat
     8041 agctatccct cgaaatgccg gcacgatttc acctaacagt agacgtacac cagctagcaa
     8101 tatatacaca cccactacga attggatggc ttgtaaaaag gcaaacatga tatagttttg
     8161 atctcctgat aattcagaag cgaatggttc gcctgcaaat aaaacagtga tgatatatag
     8221 cgggaccatc acgaccatga cagacaaata agtatcttgc agaaattcga aatgtgtcgg
     8281 caacttgata tcttcgatcg actttttatt ttcgcctttc tcaccaaaaa gcttagcaac
     8341 accggcttca aataagtacc cgatcgtaca aaaatgacct aaagcaatat catttgatcc
     8401 agtgatttta cgaatgatcg gttgcgctac tgccggcata gcaatggcga aacaagctcc
     8461 gataaaacca ccgaccaaga tcaatacgat ccctcgcaga ccggcaaaat agccaaagac
     8521 tgtcgtcatc gttgccatcc ataaaattgc ttgaccagtt aaaaaaatgt acttccattt
     8581 tgtgaaacga gccaaaataa tattgaatac aaaaatggct aagaacgtca gtgcaatatc
     8641 tctacctaaa cccaaatcat tcattgcttg accattgata gattcaatag aagggatgat
     8701 cccttgcata tgaaatcctt cagtaaagat tttcccgaaa taagttaaac ttccaacgat
     8761 gatgctcgaa ccggcactca acacttgaaa tcctaggagt gtctttaacg tgccagagat
     8821 gacttgtcct gctgatttct tctgcagtag tagacccaac atagcaatca atgcaatggt
     8881 gatcgatgcc tgagtcaaaa tattttcgat gataaaattg ataacgctca tgtttttacc
     8941 ctcttttctt tttgtattta gataactccc ttatcttgca gaactggggt gattttttct
     9001 tcaatttcat tttttgaaac aatatttttc aaatagatca tcgccgtttt aggatcaact
     9061 gcgaactttt cgaactgcga acgaaaattt tctgctgtga tgatcacatc tggtttcatg
     9121 gaaactgcgg aagaaatatc acaatggtcc agtttggctt ctactcctaa tttgttcaaa
     9181 acatcctcag cagacatctg tgctgcaaaa ctacttccta aacctgcgcc gcatacgaat
     9241 aaaatgttca atttgttcat ctttgttctc ccccgtatca tttattattt ctcaactact
     9301 gaaaaaagca gttgtttgaa atcttcgata tttgtgcatt caatcaatcg atccaacttc
     9361 tcttcgttgt tgatcaattc aattagttct ttcatgatgt tcagatggga gtaggagtct
     9421 actgctgcca aacaaaaaat aatctttact ggatccattt caggattacc gaaatcgatt
     9481 ggttgctcaa tcgtagctac gctgactcct aatttattga ccccatcttc tggtcgggca
     9541 tgggctagtg ccatgtgttt gccaatcacg atatacggtc cgtaatcatt cactgcacga
     9601 atcatcgctt cgacatagcg ctcttcgaca atgttttctt taaccaatgg tctagcagct
     9661 agttcaatcg attcctccca agtagtggct ttttctttga tcatgatatt gctgtccgtc
     9721 aaaatatctt ttaacatagg ctggatctcc cttttgttga tttctaaatt gtttgtttcg
     9781 aataattttt ctaacttgcc atagatgatt cgatctactc ggccaccact ttctttcatg
     9841 acatctatta tttgagtgaa taactccgtc gattcatgac tgttaggctc taaccgctgt
     9901 agttcttcat ttcttttcaa aaagtcttct ataaccaaga tattcgtctc agttaaaatc
     9961 ggatcgacaa ctaaaagcgg cttatttcga taattcaatt gaaaggtgct gaaaaccaga
    10021 ttgacatcca atttatctac taattcgatt tcttttgaac ttaaaactgc agtaatctcg
    10081 atctgaggaa acttttcttt cagattctct gctaacagat ttccagtagc catcccatgg
    10141 ttacagacaa cgactgattt ataaacataa ttcaagtctc gcttgattac actggcgatc
    10201 gtcgaaaagt ggatgacaag aaaagctatc tcgtcctcca gtatcttgcc accaattact
    10261 tcttcgatcg taggaacaaa atgagtgact gcgcggtaga ttgggaaata atttgttcgg
    10321 atgttttctt tcaatggatt catgacttgg atatgattct tgattcttac aatcagtgca
    10381 gccatgtgct tatagagatt ttcgaataag gcttcttcct ttagatggaa aggtacgtgt
    10441 gtctcgttct ctacaaattg gatcaattgg atcgttagta attgagcttg tacccactcg
    10501 attgaattgg agatatctct agcattgaac gtctcaatag tgaaacgaag ataatttctt
    10561 tctacttgcg ggacattgtc caattgaaat tcctcgatca tgtggtcaat aaatgcagaa
    10621 aagctactgt cttttatttc tgtatttttc caattaatgg cagagataaa ttcatgtttc
    10681 ctgattcgct ggatccagat caatgtaaaa agcaggattt gttttttata aatatcatct
    10741 tcttgtttca acaacttatt ggaatagatc tcctgtattt ttttgatttc ctccaaagga
    10801 aaataatgga gaaagatttt ttgagccggt gttaattgtg catcttgatt cataaagaag
    10861 tcggtcattc ccagattctg attgataaaa tcatagatca tcgtacggat agatcgttct
    10921 gaacctttat aaaccagtcc ttgctttcca taactgacga tctctatccc ataactgacc
    10981 agtgttgctc gtaaccgtct catatcttca tctaatgtac ttttagagat ttgaaattct
    11041 tcttcttttt tgtttagatg gatcgggatt cggctgtaag caacggctaa aactagatca
    11101 aaaatacgtt cgcgccgatt caaaaagccg tctttcacat cttttatttc agtttctaat
    11161 cgagcttgct tttccttttc cagcttcaac aaaaaacctt tgttgcgaat tgtacggatc
    11221 tccggaagct ttttactgct caaccagata ttcgcttcaa gaacttcctg acgaatcgtc
    11281 cgctgactga cattgaactc acttgctaga tgttttgctt ttactggata ttgggctgtc
    11341 atgattctgt gaagtatttc aattgttctt gttttcatag aaatgatctc cttctgattt
    11401 caagtatatg gttccgctta cataataaaa agtagatatt tctgccactt gaagtggaaa
    11461 gaaagtaagc aaagcaaaca aaaaataagc catatgcttt ttcatctcct caacgaaaaa
    11521 gacatacgcc tattattaca aaaattttgc ccatctatac aaaaaagagg ttgtgaaaaa
    11581 gctgtcctgc atcaagtaat aagaacaact aaactaaaat agtgcttcct attttttgtt
    11641 tggttgttct tattatcgca gatgcaagct tttaaacacc atttagtgga gaagctgtga
    11701 cagagatgtt cagccttgag cgataagaag cgattttgaa aaatcgcttc ccatatttta
    11761 caaaatcgtg ccttattgcc gataggctat ctctggaaca ccgtttattc agaaaaagga
    11821 gctgcgacaa ggcttttgtc acaactccgt tcataaatat ttcctgtcaa tccagcataa
    11881 tcggttgaat aaaatcggct tgccatcttt tttctttctc agaaaaatca aaataccata
    11941 tctgagaaaa atactgtcgt tgtgtcttac ttcctgagat caatcgccca tcttttcgat
    12001 cgactgaata atcacagcat ctgaaatcaa ttcggatggc aaaactattt tcgtggatct
    12061 gtcgataatt tcctacttcc tgaatagtta tttttttagt atgatttctt acaccgtctg
    12121 ctttgttttt ttgcagaact ttctgatgtt cggcaaacag cttgtctgta taacagcttc
    12181 tggctttttc aggagtttct tcttcccaag cggattggat cttcatgaat atcttttgga
    12241 tttccaaaaa ctgtgctttc ttttctttag ccgttcctga catgcgggac aatatctccg
    12301 atttcagcct tttcttttgt cttttattct tgacgataga aaaagcagaa acccctccta
    12361 ctgacaaaac agctaatgca agaaaccccg tttgctcata actagaagga cctgtacttg
    12421 gaccataata cccataagaa tctctgccgt aagaacgact gccaaaataa ctgcccccat
    12481 atgaacgacc gccaaatgaa cctctgcccg aacttcgacc gctagatgta cctccaccat
    12541 gaccacccgc gacagcgaat ccttgggtcg gcagagcaaa caaacatagg cccactaaca
    12601 aaatgattgc taaataattg attttttcat tgtcttcctc gttatctttt attacaaaaa
    12661 actattttta tcatagcctt gctaaaagga agagtcaata accagatgca taaactgttt
    12721 ttttagcaat tttgtcttat ttagtcattg agtaacatcg gacagatgta tgtgtcggca
    12781 gtccataatt cctctatctt cagcatgaac aagcttgcag acaagagatc tgcgcttcct
    12841 ccaggagaga tttggttttc ctgacaaaag tgcaacagtg ctgtaaatgg acgatttggt
    12901 aaagcacttt gactagcagc atgagcaagt ttttgcattt ccactaacgt tttctgatca
    12961 ctgcgatgca atacgcatgt gtcatctagc gaactcatca aaactaacaa catatgcatt
    13021 tgtttctgta catatgaatc attatctagc tccttagctg cttggattgc aagcctgata
    13081 tgcggatacc ctaatatcgc ttcttcatat gcaccattta cgccatattt ttgcttcacc
    13141 ctatgaccat gagtggtttt tttatgacga tattttgtat caggaaaagc agcaagcttg
    13201 ctgacatcat caagtatttt cgataaagaa aaaggctgtt ccatactgat tttttgtgca
    13261 atgacactga tcaatagccc cattgcccaa atcgctcctt tatgggtatt gatgccattt
    13321 gtagcaatca gcattgcctt ttccgctttt cgcccaatct cagcaattct ttctcttaac
    13381 tcctgatcaa tagcataatg ccatgctatt tgagccattt cttcaaaaaa aggagttagc
    13441 gtcttagcag acttatccaa aatgcgccga ccttctttta cggcttttgc gatcgtatgg
    13501 aaattatcat ctcctaaaac catatcagct gcctgtttgc ttacttcact acctttgatt
    13561 cccatagcga ttcctatatc ggctcttttc aaagcaggtg catcatttac gccgtctccg
    13621 gtcattccga cgatttctcc atttttctgc aaagctttca cgattcgcag tttgtgttct
    13681 ggtgtcgttc gagcaaagac gtcgactttt ggtacttgtc gaatcaactc ttcttcagac
    13741 ataagatcca aatcgatccc ttctaaaact ttagcagtat gttttaagcc aatttgttcc
    13801 gcgatcgctt ttgctgtatc tttgtgatcc cccgtaatca ttttcactga gattcctgct
    13861 tgttggcatt cctttacagc tttgactgca ctttcttttg gcggatcaat caacccagca
    13921 atccctgcaa aagttaattg ggttaaagac tcatgcgtga gttcctgttt cgaatctact
    13981 tttttgtaag caaatcctaa aacacgctga ccttttttcg caaacgctgt ggctgtttga
    14041 ccccatgctt cttattctga agaagaaaga gttgatttag ccaataatac ttctggcgca
    14101 cctttgacgt aaatcacccc tcctttttcc tccgcatgca tcgttgccat atatttgtat
    14161 tcagagctga acggaatttt tgcttctatt tttttcaaag gcagatcggc tgtttcggtg
    14221 tggcgaatca gtgcaagttc tgtcggattg ccacttaaat tttctgtttt ctgttcttct
    14281 ttcgtcttta attcctgaca atttttcata ataaacagta cgcgagtttc ttcctttgct
    14341 gctacatcca caactgtcat ttcatttttt gtcaatgtcc ctgtcttatc tgaacagatc
    14401 actgtcatag aacctaatgt ttctacagaa ggcagtcctt tgatgatcgc cttttctttt
    14461 gccatttcat gtactccgac agataggatc atggtcaaca cagctggcaa tccttcgggt
    14521 accattgaca ccaccaaagc gatcatagct gaaagaagga tatgccaatc catgccatag
    14581 cggaatgttg taaaaacaac taagaacaag atcaaacaaa gaatgccttg aaaaatttgt
    14641 ttgttcaatc ggttgatctt cttgatcaga ggcgtcgttt gttgttcgac cgattgcagt
    14701 gcttgattga ttttaccgat ttctgtcgtg tttcctgttt ctacaacgac accgactgca
    14761 gaaccagatt gtacaagcgt tcctgaaaaa gccatatttt tttggtcacc gattgattct
    14821 tctgctgcca aaacggaatg atttttttca gatgcttctg attctcccgt caaaatcgat
    14881 tcttctacta gtagatcatg tacttcgatc aaccgaacat ctgctggaac gacgtctccg
    14941 gcacgtaaga caatgacatc tccttttact agttctttcg cagggatttt ttcttgcatc
    15001 ccgttcgata gtactatcgc ttcttgtccc atcagctgct tcaaaccatt caacgattct
    15061 tctgcttttc tttcttgcca ataactaacg agtccgttga cgatcactac gaataaaata
    15121 atacttcctt cgatgtattc gctcgaagca aatttcaaaa aagaggcaat gatcaacacg
    15181 atcatcagca gatcagtaaa gtgttttgct atttttttcc atcgttttgt ctgctgtctt
    15241 gcttctatct cattatatcc ttgatcagtc aggcgtttct gccgttcttc ttgcgacaag
    15301 ccttctgttg atgtttgata gtttttcaat acatcttcta ccgtcaatct gtaccagttc
    15361 atcctatccc ctcctgttta attgatactg ttattatacg cagggaagtt ttttcaggcg
    15421 tatcgattat ttcagggggg tctgaaataa ttcgttttgc agaatgtatc tgggcctaac
    15481 tgatatttct attgcttatt cttttatata caaaatttaa gaatacaaac cagataacca
    15541 ataaaaaagg aataaagcgt gtcgtgcttt cgaataacaa gctgaaagca attgaagtaa
    15601 aaaacaccaa caaagcaaga tctttatatc tttgtgtagt gttccgtttc ttttctttaa
    15661 ttaattgaac atgtgcacac aagatcgaag accacacaaa tagaaaacaa ctcgttgtca
    15721 tgcctgccaa aagctgaaaa aacaatcgac tatcagctac aaaaaaatgt agacaaagac
    15781 cgacaaaaaa taacatccct gtaattaaaa taccgtgtaa aggtacgcct ttcttagaaa
    15841 gcgcacaaaa ccaatggggc aaacttttct cttttgctgt ttgatataaa atcctgctag
    15901 tactgtagac tgcactattt gctgaggaca aagaagcaac caaaatcatt agattgacaa
    15961 ttgctgctcc gctttggcaa tggatcactt gcagcatagt cactaaagga ctttctttta
    16021 aatctaaaca atgccatgga acaacaaata aaatcgacaa aatcgttcct atatagaaaa
    16081 agaggatacg ccaaggcaga cagttgattg catttttcaa attcttttgt gggtcactcg
    16141 tctcaccaac tgttaatccg atcatttcaa ttccagcaaa actgaataaa accataggaa
    16201 atgaagcaat cattccagca aagccaaacg ggactaattc attgagctgt ccaaaatttg
    16261 ctttgattcc aatagactgg gtatgaaaat ctgagacact caatcctata cccaataaga
    16321 taaaaaggaa aatccccaag atcttgatga ttgagaaaaa agattccaat tcaccaaacc
    16381 acttgactgc aacaaggttg actgccatta agatcattag tgcgctacct ccgcttatca
    16441 aagctggtac atgtacaaac cagaaatgga tatacaatcc tattgctgtt aattccgcaa
    16501 gtccagctcc aagccagcaa agccaataag tccaattgac aaaaaatgcc cactttttgc
    16561 ctaaataata gtcaacgaaa tcactgatag agttaaatgt actatttgct aaaaataaat
    16621 cacccatgac ccgcatcaaa ccataaatag ccaaaccgca tatcaaataa acgagaataa
    16681 cagctggccc tgctgatgca attgcctttg ctgaacctaa aaataatcct gttccaattg
    16741 cgccacctaa tgcgattaac tggatatttc gattagttag agtccgtttc attgccggtt
    16801 tttccatcaa gttcaccttt ttctttttca agcagcatgg cgacttcctg ttcccaagaa
    16861 ggtttcttta ttttttcaat acagagtggt actacaaaca aaatgacact gatggctgtg
    16921 actgcaatta gattgatcca tgtcccagct ttcatcgtca gtccgacaga aaatccgatt
    16981 gccgcaaata aaacaataac gacagtccaa actccaagat tgctcttttt ctcttttttt
    17041 ccaattctaa atggtcgatt caactttgca tgtgtataac gcaatctcaa aactgcgatc
    17101 cccatgatga catagacgat acagtagata acagtagttg aatttacgag catcaaaaat
    17161 gcttgattga cgccaggaat cagcaaataa aaaagtgcaa agattgagat aatgacagac
    17221 tgagtcaaaa taacggattt ggatacgtca aattgattcg tcttccaaaa attgaatttt
    17281 ggtggatacg caccttttct agcactttct gtcactgtct ttgctggtcc tgaggcccaa
    17341 gcagataatt ggactgctac accaatgaag acaagtaaac taaacagatt cacaataaga
    17401 tgtggcaaac caagaatttg gcaataaatc gaaatagatt gcgcgatatt attcaattcc
    17461 atttgtcctt ttggtacgac atttgctaca actaaagcat tcaaaatatt gacgaaaaat
    17521 ataaaaatta acgcggcaaa tactccgcga atatacgttt taactggatt tttcaaccga
    17581 gtgatataca cagaggacat ttcgatacca gtaaaaataa acatgatcgg cgcaaaataa
    17641 acaaatgagg atgcagtcgt agtatctggt attaatttgt cccatgaaaa actgcctaat
    17701 gttccggttg gtacgatccc aactttgatc cacgcagcaa accctaataa gagcatcatc
    17761 gtcaaaggca cgtacaatcc taaccaaaca ccgacttttc cgccgatttt tgccatatca
    17821 aatttcaaat tcaaaaaagt gatgatccaa taaacgacta aaatgacaac taatgtaaat
    17881 ttgctgttca aaccaagcgg cacattatcg ataatattac caaacaacgg agcaagtgct
    17941 gaagcgacca tcaccatccc aggaaacatt tggacccata acagccatga gacaacgaac
    18001 ccccattttt ttcctagagc attcgatacc caaagttctg gaccaccttt ttggggaaac
    18061 attccggcaa attcaccaga gatcaatgag attggaaaag cgtacaataa tactgcaacc
    18121 agcatgtaaa aaatcatcgt ccagctcgtt gctgctacat ctggaatatt tcgtacactt
    18181 gctacaaggg cgcaggtcat tccgataaag gtcatggtcg tgatttgctt tgatgaacca
    18241 gtatctttca tctttattcc ttctttcaat agcgacatat gtttttgttt tcttttattt
    18301 ttgttcaaga acagaaatga caaggtttca tcgattcagt acaaaaccca gtatcaccga
    18361 aacatccatt gaacgatctt agtgaactgg gtttgataca tgaaacgaac gatccaactt
    18421 atagaacgtt ttataaaaaa gaatatcttg gcgaggaata tatgaaaaac agggggaaat
    18481 acaattgttt tgatgaagca aataattgtc tgttctccat atgtctcttg ttattctttc
    18541 acacaaaaat cagttctatt ggatgatttc gtttagtttc ttttccattg ctttggcgat
    18601 ttcttttgta taaaaattga aaattcgatc atcattcaaa taaggagtca tgatagccgc
    18661 acgtagcaga gtgattttct gttctttttt ccattcttct ttcgttagac ccattctttc
    18721 aacaaaacga atcggagaat caccgtaatc ttcttgtgta aatgtagtat gagaagtaat
    18781 aaaccgttca ccataaacat cgccatccat ataagaagac cgatcgaaca ttttttcatt
    18841 taattcattg atagcgttca aatctgtaca gccttgttct ttgaataccc aattgaccat
    18901 attaaaatca ggatgattca atggatagac ttcgattgtt tttcctttaa cagtaaaagt
    18961 cagatgatcg agaaattctc tgaatctttg agctgcctcg attgaagccc caatcaattg
    19021 accatatccg gtcacattca atggcaatac acgatgtgct gtccagactg cggcggcggt
    19081 tgctccagct tttgatcctt ccaaaatata agctcctaac atatctggag cctttactga
    19141 tttttcaaac acatatggcg cgaaataaga aatgatattt ctcatatttt tatgtttgat
    19201 tacgattcct ccagcagcat aagggacata gcccatctta tgaggatcta tcgtgacaga
    19261 atccgcttct gaaatagctc tgaacccttc atatacctct ttgtcaatcg ttacgcagtg
    19321 gtggaaaaca tgatgttctt caaagaattc agctaaggaa gcatacggca caaattctcc
    19381 tgcttcgttt agaaacagtg aacgcgcata gccgccatat gcggcatcaa catgtaaata
    19441 gaaatagatc ccttcatctt ttaacctttc tcttaattgg acgattttat ctacactgtc
    19501 tacttgacct tcttctgtcg ttcctacgac agcaaccaca cctagaattg ggattttttg
    19561 ttcagctaat tcacgaattg ttttttccaa agcattaata tccattcgat aatcctcttg
    19621 aactgggata gcaaccatct gatctaagcc tactccgcaa atatctaacg ccttcatcca
    19681 agaatagtgt tttgtttgag gcaccagcca tttccctaat ctttggatat tttttccgct
    19741 acgggaagaa gctgctttga cctcatccat ttcttcgtcc gtaaagcttt cggtcatttc
    19801 caaaatttct tcaacagata aattcaaaag ttcccactca gacatttttt tcacttgttc
    19861 aggcagcact tccttgacag ctaaaggaat cgatttgatg cagcgggcgt accataatcc
    19921 ttcaagatta gcaatagaac catctgctgc aatgtgtccc catccgtctg tcatattgaa
    19981 taatgaagca aaatcctgtc ctacttctgc ttccatttgc gaagttgcca tagaagattc
    20041 caatgcaaca ttatttgggt tccacagcat cgcatagttg taagctaata aagcaggcat
    20101 caatgtttca gcattcattt gtccccagta acggcctgct gaatgccatg ggatcgatcc
    20161 tgcgcgtaat cgctgactga cttcatccaa gacctctatc atatggtcgc gggtggctag
    20221 ataatctgga gtgagcttat ctccttcgct aattgcaggc atatctgaag gaatataatt
    20281 ttctctccat ccaagatgtt catctaccat cttgttcaac aacattttat aaactggtcc
    20341 attttcagct ttgtcgccta taaagacggc cttgatatcc atatctttca tttttcttcc
    20401 ctccatattt tgttggtcaa tgtctcgcag atacatgtgt ttatctgtaa cacctcttca
    20461 ctatagcgcc aaaaatgaga aatttttttt tataacatca aatccacgta gatttttaca
    20521 acgcgaattg taaaattaag ttagaaaaat aaaaaggcat ttatggtaca ctcaaattgt
    20581 atttccgacg aaagaaaaca aaggagtgta accataaatg acctacaaac atcttaccat
    20641 agacgaactg acaatgatag aatcatatta tcttcaacat aat
//
LOCUS       DAFEKH010000050        20664 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.052, whole genome shotgun sequence.
ACCESSION   DAFEKH010000050
VERSION     DAFEKH010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20664
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.052"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            168..362
                     /locus_tag="LP386_002103"
     CDS             168..362
                     /locus_tag="LP386_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919332.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            631..930
                     /locus_tag="LP386_002104"
     CDS             631..930
                     /locus_tag="LP386_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919333.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(1027..1461)
                     /locus_tag="LP386_002105"
     CDS             complement(1027..1461)
                     /locus_tag="LP386_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1919334.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1693..2403)
                     /locus_tag="LP386_002106"
     CDS             complement(1693..2403)
                     /locus_tag="LP386_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBL1919335.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2393..3253)
                     /locus_tag="LP386_002107"
     CDS             complement(2393..3253)
                     /locus_tag="LP386_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HBL1919336.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3258..3896)
                     /locus_tag="LP386_002108"
     CDS             complement(3258..3896)
                     /locus_tag="LP386_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HBL1919337.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3911..4210)
                     /locus_tag="LP386_002109"
     CDS             complement(3911..4210)
                     /locus_tag="LP386_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1919338.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4253..5737)
                     /locus_tag="LP386_002110"
     CDS             complement(4253..5737)
                     /locus_tag="LP386_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBL1919339.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5757..6218)
                     /locus_tag="LP386_002111"
     CDS             complement(5757..6218)
                     /locus_tag="LP386_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL1919340.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="LP386_002112"
     CDS             complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="LP386_002112"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HBL1919341.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7521..8291
                     /locus_tag="LP386_002113"
     CDS             7521..8291
                     /locus_tag="LP386_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBL1919342.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8564..9391)
                     /locus_tag="LP386_002114"
     CDS             complement(8564..9391)
                     /locus_tag="LP386_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1919343.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9959..11194
                     /locus_tag="LP386_002115"
     CDS             9959..11194
                     /locus_tag="LP386_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBL1919344.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12193..12453)
                     /locus_tag="LP386_002116"
     CDS             complement(12193..12453)
                     /locus_tag="LP386_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBL1919345.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12480..13781)
                     /locus_tag="LP386_002117"
     CDS             complement(12480..13781)
                     /locus_tag="LP386_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL1919346.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14073..14531)
                     /locus_tag="LP386_002118"
     CDS             complement(14073..14531)
                     /locus_tag="LP386_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL1919347.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14544..15875)
                     /locus_tag="LP386_002119"
     CDS             complement(14544..15875)
                     /locus_tag="LP386_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HBL1919348.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15886..17328)
                     /locus_tag="LP386_002120"
     CDS             complement(15886..17328)
                     /locus_tag="LP386_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL1919349.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(17315..18079)
                     /locus_tag="LP386_002121"
     CDS             complement(17315..18079)
                     /locus_tag="LP386_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HBL1919350.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(18183..19058)
                     /locus_tag="LP386_002122"
     CDS             complement(18183..19058)
                     /locus_tag="LP386_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL1919351.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(19313..19397)
                     /locus_tag="LP386_002123"
     tRNA            complement(19313..19397)
                     /locus_tag="LP386_002123"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19361..19363),aa:Leu,seq:caa)
     gene            complement(19415..19486)
                     /locus_tag="LP386_002124"
     tRNA            complement(19415..19486)
                     /locus_tag="LP386_002124"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19452..19454),aa:Gln,seq:ttg)
     gene            complement(19496..19568)
                     /locus_tag="LP386_002125"
     tRNA            complement(19496..19568)
                     /locus_tag="LP386_002125"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19533..19535),aa:His,seq:gtg)
     gene            complement(19630..19714)
                     /locus_tag="LP386_002126"
     tRNA            complement(19630..19714)
                     /locus_tag="LP386_002126"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19678..19680),aa:Leu,seq:caa)
     gene            complement(19735..19805)
                     /locus_tag="LP386_002127"
     tRNA            complement(19735..19805)
                     /locus_tag="LP386_002127"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19771..19773),aa:Cys,seq:gca)
     gene            complement(19851..19922)
                     /locus_tag="LP386_002128"
     tRNA            complement(19851..19922)
                     /locus_tag="LP386_002128"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19888..19890),aa:Gln,seq:ttg)
     gene            complement(19934..20006)
                     /locus_tag="LP386_002129"
     tRNA            complement(19934..20006)
                     /locus_tag="LP386_002129"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19971..19973),aa:His,seq:gtg)
     gene            complement(20009..20082)
                     /locus_tag="LP386_002130"
     tRNA            complement(20009..20082)
                     /locus_tag="LP386_002130"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20048..20050),aa:Trp,seq:cca)
     gene            complement(20089..20169)
                     /locus_tag="LP386_002131"
     tRNA            complement(20089..20169)
                     /locus_tag="LP386_002131"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20133..20135),aa:Tyr,seq:gta)
     gene            complement(20171..20246)
                     /locus_tag="LP386_002132"
     tRNA            complement(20171..20246)
                     /locus_tag="LP386_002132"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20211..20213),aa:Phe,seq:gaa)
     gene            complement(20282..20354)
                     /locus_tag="LP386_002133"
     tRNA            complement(20282..20354)
                     /locus_tag="LP386_002133"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20319..20321),aa:Asp,seq:gtc)
     gene            complement(20364..20436)
                     /locus_tag="LP386_002134"
     tRNA            complement(20364..20436)
                     /locus_tag="LP386_002134"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20401..20403),aa:Val,seq:tac)
     gene            complement(20452..20523)
                     /locus_tag="LP386_002135"
     tRNA            complement(20452..20523)
                     /locus_tag="LP386_002135"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20488..20490),aa:Glu,seq:ttc)
     gene            complement(20538..20627)
                     /locus_tag="LP386_002136"
     tRNA            complement(20538..20627)
                     /locus_tag="LP386_002136"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20591..20593),aa:Ser,seq:gga)
BASE COUNT         6531 a         4319 c         3275 g         6539 t
ORIGIN      
        1 taagaacaat agccttttat tatatatatt attcaaatta gttatatcga gtgaaaaaaa
       61 ctttcaaatt gattcttttt atttatcata aagatataga tacataatca ttttcactta
      121 catatatttg aatattaact aaaaacagca agaaagaaga ggatcaaatg tattatgtag
      181 aagtaaaaac aaaaggcgtc aaaaacaaac aatatgtgaa aggtatcagt aacgaatatc
      241 ctttacttgg ttcatggaaa gaagctgctc ctttttccaa accatgtgcc ataaaaataa
      301 agaacgagct agaaaaagaa ctgacttgtg gtaaagctgt tgtagatatc atcgaaaagt
      361 aaatccaatg tatagaaagg aagatcacac atgaaaagcg acgtacaaat tgctaagatt
      421 atagaattag aagaagaaga cgcagtgttg acaattgaaa aaaaataaat gtttgtatac
      481 catatgatta tttcaatatg tatcctggaa ttggagatct cgtagagcta tatcaagatg
      541 aatcaaatat acttgtcatt catcatgaaa tatagagact tataaaattg tttattttta
      601 taatgtatca gtatagaaag gaaataaaac atggattata ctgttgaatt tgacagtgaa
      661 ctacttaagc aatttccaca agaagaacat ttcatgtata aagaagcaat ttcccacaaa
      721 gtgacagagt atttggagca taattttttt cgtataaagc cagtgcgtac tcgttcggca
      781 aaaggaatat acgagatgaa agtcaaaatt aataaaaaaa attatcgcat agcatttgct
      841 ttaaaaaaaa atcatgtgtt cattttttat attagttcga atttgcaaaa aattgtattt
      901 gataaagagg tgagtaaaaa aataaaatag ctgagcattg gaggatagat tgagtgatac
      961 taagtctatc ctcttgtttt tctaaagaac taagctagaa ttttttcttt tgtacgttat
     1021 tatatgttat ttgtcattac caaaaagcac cttttttctt ctagtatcta tgacataaga
     1081 aataccaccc atttccttta cttgaacaaa tcctactgat tcataaaatt tttttgtttt
     1141 ctcagtatca tctgtcaata attcgatttg gactggtcca taactagtga tcttctccaa
     1201 agcttcattc aaaagcactt tgcctattcc ttggcgctga tacctcggat gaatgaggat
     1261 atcttgaata aatgcgatcg tcgcaaaatc agtgatccaa cgaacgattc cgataatctt
     1321 cccttcccca ttacgcttta tcagagattc agattgttca aatgctctag ctaaccttgc
     1381 agtgtctttt gtgtaattcg tccaaccaac gctcttatat aattcagaaa tctcatcgat
     1441 cataagggaa tcaatattca tttttttctt cctttcttat acaattctcc ctctaataat
     1501 acagttcttt gactatttaa tctatcacat ataactctcc tgtaaagatt ctctcgattc
     1561 cttaaaattc ctctttcctt ttagaatgca tactttttga taaataaaaa ggttgtgata
     1621 aattttcttc acaacctctg tttctctcta tcaagtgtta tcttttaatt ttctaccctt
     1681 accctagcat ctctattgcc cgtagtatgc atactttcca tgtttgcgaa aataatgttt
     1741 atctagtaaa tattgcggga tttcacatat attggggttg atcagctcgt tttctttggc
     1801 catcagacaa atttcatcta agatcaaact gttttctact gctttcatag gtgaatcccc
     1861 ccatgtgaac ggtccatgtc catagacaag tactccaggg acttcgtttg gatctaattt
     1921 tctttcctta aacgtctcga caatcacatt ccctgtatga acttcgtaag cttctcttac
     1981 ttcttctttc gttaattggc gtgtacaagg aaccttacca taaaaagcat cagcatgagt
     2041 cgtgccataa gctggcaaat cgcgtcctgc ttgcgcccac atgacggagt gcgtggaatg
     2101 agtatgagta atagcagtta tatcttcaaa agtttgatac aaaacaacat gtgtggggag
     2161 atctgaagat ggttttaagc tatcttcttc tattatattt cccgacaaat ctgttaccac
     2221 catttgatct gcttgcatgc attcatatct gacaccgctt ggcttaatga cgatgactcc
     2281 tagctcacgg tccacttcac tcacattgcc ccaagtcaat ttgactaatc cgtatcgcgg
     2341 caatgccaga tttgcttcaa ggacacgttg cttcattgct gcaatttttt cttcacaaga
     2401 catcatagcc agcctccttc aatttagaac ttaagtagtc ttttgcctgc tggatttctc
     2461 ttcgaaagtc ttggcttttt tcactccaca tttcaatcag aaatgttcca tcataatcta
     2521 gacgtttcaa atgtcttaat aatccaagaa aatcaacaca accgctacca aaaggaacat
     2581 cacgaaactg gcctgaatat tcttttgtta cagggtaagt atcttttaag tggatagcag
     2641 tgatataatc gatccctttc tcaagttctc gagccggatt attttccggc catgcggaca
     2701 aattgcctag gtctggatat acttgtagaa aaggtgaatg aatctgttct ttgatttcta
     2761 aaaattttga aatggagttc ataaatggat catccatgat ttccacggaa agaatgatgc
     2821 catatttaga agcttccttt acgctttctt ttattccttc gataaagtct tctctggaat
     2881 tcattgattt ctcttcataa taaacatcgt atccagctat ttggattact ttgacgctta
     2941 gattatgcgc caaatggatt gcttttttca ttagttgttt cgctgctttt ttcttttctg
     3001 gatcagcaga accaaacgga aatcgccgat gcgcacttaa acaaatcgaa tggatacgta
     3061 caccggagct gaacatctct tctctcagct cagctatctt ttcttcagac caatctaatc
     3121 gtgctaaccg ctcatccgtc tcatcaatcg acatctcgat aaaatcgaag tccatttctt
     3181 ttacaaggga aaaacgttct ttccatgaaa tatctttggg taacgctttt tcataaatcc
     3241 caatttgagc catttcctta cccccagata cgaatgatct catctttgaa gttttgtgcg
     3301 gccttcatcg gatcatttgc tgctgtaata ccacgaccag tgataaaggt atacacatcg
     3361 atcccttcaa ataagtgtaa tgtgtgtgga tttaatccac cagttacaga aacattaaag
     3421 cctagttcaa tcagtttttt gatcttcgat aaatcttttt caccccaagt ttcaccagat
     3481 aacagcgcat cacggctttg atggtagatt acctgccgga taccgatgtt atgccaatcc
     3541 atggcttgtt caaaagtcca attgccgtag agttctactt gcaattcacc tatttctttt
     3601 tgtgctgcct ccatagttgg aatcgttgca caacaaatga ctgtcatcca gtctgctcct
     3661 gcttttgcaa cattactcgc cactgttcct ccagcgtctg cacatttcgt atcagcgact
     3721 agttttttat ctgggaacat actgcgaata cagcgaatcg ctttttgtcc ttcctgtaag
     3781 caaagaattg tgcccacttc aataatatct actacatcac caactttcat aacatctcct
     3841 aatgcatgtt ctaagtcatt gtgatctaac gcaatttgca aattcggcct gctcatctta
     3901 gttccttcct ttacttgttt ttttggtacc actttgtttc agcaaatttt tcactgattt
     3961 ctttgactga catcacattt ttgataccga taactgtaac tccttttttc tctgcctgag
     4021 taaacatatt caaaaaattg actggcgtaa aaactacatc gtattggcca gctgaacttt
     4081 ttccctctga aatggcacaa tgatggattt tggtaattgg tacgtttagt tctttcattg
     4141 ctttttccac acttctcatc atcatcaagc ttgttcctga tccatttgca cacgatacta
     4201 aaattctcat cttaatccct ccattatgag tgttgtctaa tcagattttc ttttatactc
     4261 tctgcttttc tgcatatgtg tcatagtctt ctacaatcaa aaaataacca tcaggatttt
     4321 tccgatattg taactgcgga atagccaata aaccaatgac aactacggca attccagcat
     4381 aacctaggac tttcatgatt actgtaaaca atggccaagc tgttgcccag tcgaacatcc
     4441 cgatataacc accgtatgtt gacatcccaa tccatgtagc gaataatgct gaaccgccta
     4501 cttgtatgat tcctgaaaga aacgggaaca ggcaagcggc tttgaatcca cctcggttat
     4561 tggcataaac tgctataacg gcattatcaa agaacaacgg aatgaaaccg gctatgacga
     4621 tcgttggtga tttcaataaa atcagtaaac caatcatcaa aaactgtccc aaagcaccaa
     4681 acaagaaccc aatcgttacc gcatttggcg aaccaaagcc aaaagtagca gctacgtcaa
     4741 ttcctggaac agctcctggt aaaatcgtgt ttgagattcc ttggaaagat tgagttagtt
     4801 catcgacgaa tgtccgaaca cctaattgca agatcgccag atataccgca aaatttaaag
     4861 aagtcgtcat aatgtagaat aagaaactct gcccttcttg catgaattgc gcttgaatca
     4921 aataatcttt gcctagtaca atcagaatga tcccaaagaa aaatagcatg agtaacgaag
     4981 tagcaaccat attctcattg aaaatcgaca agaatcctgg taatttgata tcttcaattt
     5041 ttttgtcttg cttgattgat ctatttttct tttcatcccg ctttttcatc cactcagcta
     5101 attttgcaaa tataaagatt ccgaacattt gctgatgtgc cactgcaaat ccggcacctt
     5161 ctgtcaattc ctgcgtgatt cctactgtta agttagaagc tactgtccaa taacaaccta
     5221 aaatcagtcc cataaaaatc aatgcttgta tcctacctag atcaggaaag caaaacagta
     5281 aaatccaaaa agcggtagct gcttgttgaa cctgaacgtt tccggtagtg aaaacggaac
     5341 gcagtttcgt atatttctga aaacggacta ataagatatt taaaacaaat gcaatcagta
     5401 ataaaatcat cacatctcca aaggtacggc caaatgtctc cattaatcca gcatccacag
     5461 cattttgtcc aaaataagga tctgtaacca tggcatccaa attgaaccgt tcctttagtc
     5521 caaccaagat tggccgaaaa ttattgacca aaccaccaga gccaacagtc aaaataaagt
     5581 aaccgaccgt tgcctttaag aatccagcga tgcattcatg aagcgggcgt ttcagcaaaa
     5641 tatagcctaa taacacgata aaaccaatca ggtatgctgg ctgcgtcaag atatttgttg
     5701 caaaatacgt ccaaatgctt aacaaaaatt cccccatctt ttttctcctc tatcaattaa
     5761 ttatattctg ccatcacaac ttggtaatca tcgatggagt tcgtagagat gagacgctca
     5821 accaatccat ctgtcattaa taattcggat aatttttgga tattttctag atgttcttct
     5881 ggatcttttg ctgcgagtgt aaaaaacaaa ctagccgttt tctcctcatt ctccccttca
     5941 ctttcaaaac ggattggctg tttcaacttg gtaaatgaaa tagctgttcc aaaaacacca
     6001 tcactttttt ctgaagaatg cggcattgct acttgaggtg cgatcacaat ataaggaccg
     6061 tatttttcta cacaatggat gatctcctcc acatacgttt catcaataat ttccttatcg
     6121 atcaatacaa gacagctttc ggcgatagct tcacgccaat ccgtgatttc tttatctggg
     6181 taatgaatca attgatggtc aaaaaagtat ttcagcaaga aactcccctt ctttcttata
     6241 aaaacgacgg aaacggtgta tcattttcaa tcgagaagac atcttcaaat cctcgataaa
     6301 aattaaactc aagatcatct ttgtttgtcg gatagatgaa tttcccgcct acttgccaga
     6361 tataaggttt aaatccatac ttcaggcgat cctttttgaa tttccaaatt tcagtgatct
     6421 cttttggatc agccataaaa ttagaccaaa tatcgtagtg gacaggaatc actacttttg
     6481 cattcaatga ctccgccatg cgcagcatat caacagaagt aactttgtct gttatccctc
     6541 gtgggttttc accataggcc cctaaacaga catcgatttt gtgttcatta ccatgtttgg
     6601 caaataaatt ggagtaatgt gaatctcctg catgataaag attccctcct gatgtttcga
     6661 ataaatagtt tactgcaatt tgatccatct cctgaggcat ttttcctttt aatacctctt
     6721 ctggatcttc acaagtgacc aacgctgtcc gatcaaacgc ttctaaagct actacattga
     6781 tgtctttgat tttgactgca tcacctggct ttactgtaat cgttttttct tcaggaattc
     6841 cccatttttg ccacgtgcga accacttctt ttggcccaat gaatgttgct tcaggacaat
     6901 tttgatgaac tgctgcggct gtatggatat ctagatgatc ggaatggata tgtgtaacga
     6961 ttaaagcgtc tacatttttt atcgcaaaag gatcgattac gaaaggctga gtacgtaaat
     7021 taggctgcat attttgaacg ccactcatac gcatcatctg atggcctttt ttcatcatgc
     7081 cattcccatg actacgtttt cccgtcccac accatagatc acataaaata ttcgttcctt
     7141 catgactttt cagccaaatt cccgtacagc ccagccacca catagcaaaa gttccaggat
     7201 ccactacttc tgtttcgatt tcttcattca agtatgtgcc ccactcagga aatgtttcta
     7261 ctaaccactt ttcttttgtt acttcattga cagttttact catttgcttg ctccccccat
     7321 atcgttgttc caacttacaa gtaaatatta atgtgtatca gcatccatga aaaccctttt
     7381 atatgaccgt ttgtttttta tatgattttc tttcagtaat caatgattgt ttcagtataa
     7441 taaagacaga tatgaatgtt taaatgaaca actagtcaaa taaatccatg gatcaagatg
     7501 tccctcagga ggcaaaagtc atgaaaaact cacttgtcaa tattgaaaaa cgtcaaaaag
     7561 aaattttgga actgcttcag cagactgaac aactatcaac tttcgaatta gctgaatccc
     7621 ttgatgtatc tattagtacg atacgaagag atttaaattt attagaagaa aaaaacgaga
     7681 tcatacgcaa ttacggttat tgttcttata attacaaaaa ccagactgat tttgatcaat
     7741 ctggtcctga aaggattaaa caagcgattg ccagagaagc tagtaaatac attaacgatt
     7801 atgatacgct gtttatcaat tctagctcga ctgcgttgaa aacactggat tttcttcaat
     7861 ctaaccattt gacagtcatt acaaacaacg tgaaaatcaa ttactctccg cacaaagata
     7921 attgtagtta tattttaact ggtggagaga tgcgctttcc aaaagaagca ctagtgggcg
     7981 acatcgcatt aaatacgatt tcttcagtca atgcagacat ttgtatcatt ggctgtagcg
     8041 gagtcgatgt agtacatggg gtcacaacaa agatattaaa tgaatcaacg atcaacgaaa
     8101 tgatggtcaa caagacaatc aaatgtaaga ttttagtcgc tgatcatcga aaaatcggac
     8161 tgacatcaaa gttcaagatt gctgatattt cagtctttga ttatttgatc actgataaat
     8221 tttgttctga aaaagtatta gaggagatca gaaatacggg gataaaaacc attcaagtag
     8281 attcatttta agaaccagga cgtaaatatg taaataggat tatcaaaaaa atgaataaca
     8341 aatttatcga taaatgaaaa acacgctacg ctcaaattga taaaggaatc ccaagatgta
     8401 tccatccaat cgataccatc ataatctatt gcttctttta taaccgttat atgttgccta
     8461 aataggaatc aaacaatatc gaaaaaagga ggtatgacaa aagtcacacc tccttttttc
     8521 gaataaacgg tattcaaatc agaacactga tttcacaacc actttatttc aggtcgtttt
     8581 caatcacctt taccgcgtaa tcatttccgt tgaaacgcgc tatttttttt gcgtccatat
     8641 atctttctaa ataatcatct tctcctaatt gcttatggca agaagcaatt tcataaagca
     8701 agtattccaa tgcataagtc gatttatgtt tcttattata ctcaataccc ttctcacata
     8761 attggattgc tttatcataa tcctcgattt tacggtaata ggtggcgata tcataatata
     8821 caatgcagac catcagatta tcaaaatcag tctcactcaa tattttaagt gtacgctcca
     8881 cataaacttt cgcaaaatct aattctcctt ttgacaagta gatcattgcc acgtttgcag
     8941 ctgcttgtaa gtgatggata tctgtttcgg tcgtttgttc caacacttga ttaaaataaa
     9001 ataatgctgc atctggtttt ttcgcataaa gatgatcaag cagtccttga taaaataaaa
     9061 tttgatttaa aagatcagaa ttacttactt tttcctgatc gatcgtttgt aaaattttat
     9121 aagattcttg gtattttgat acagaattca atgattgaat ctcatttatt tttttcctga
     9181 ttttgtcttc ttctgtttct actaatatat cggagatctc gacattcagc tttttgcaaa
     9241 gcgcacttaa gatattgatg cctggcgaca tattcttgtt ttcgatattg ctgacagttg
     9301 cttgttcaca aatgccttct gctaattgta cttgtgttaa cccctttttc tttcggtatt
     9361 cttttagtaa tgctccatct actttaatca aaacaatttc cttcccttta aaaaattatt
     9421 tctcctttat atcatacaca aaaaaaagtt ctaaacaacc aaaaatgttt agaacagaat
     9481 aaaaatttta attttaaaat aatattcaaa ttaaacaact ggcgtatctg ctccttgatt
     9541 tctttttgtg ttatctgaat aattatcgtt tacagttata acacatagtg aaaattgtca
     9601 tggcgagaaa gtctaagaat atttttaaac ataactattt ctttcttacg tgtgtataat
     9661 gacgacagca cacctatcaa ttaatataat tattttattt ttttatgttc tcatgtttat
     9721 ttttaatgac acaacttctc gtatttatct ggcacaacat ataaatcgat caaaaaattg
     9781 ttgcgtgttt ttttgaaaat tggagtttca acttgattac aaaatttaaa tttagaagtt
     9841 gtgaaaacag cgagagacag tttaatattc aaaatataca taggctactc gaacgctgtg
     9901 ttttttagta tactagtaag aaacgaaggg atagactcat tccaataagg aggatttcat
     9961 gaagacaatt ctttttgctc ctgcagtatt caatttagct gagacaacac gaatgattga
    10021 ggttgccaaa gctatgaaag accgttatta ctgtgtattc tttggctttt ctaaaacttt
    10081 tgctcctttg atcacagaaa gtggctttga gtatcattta ctagcgccga tccttacgaa
    10141 aaaacaagaa gaacaaatca taaaatttga ccagttgcgt acacttaaaa acccttttac
    10201 caaagaaatg gttgcctctc gtatcactag tgaacagagt ctgattgcta agtttgagcc
    10261 tcgactgatt gtgacaggtt cgaatgtgac aattttttta tcggcccgca ataaaaagat
    10321 tcctttagta tatgttaaac cctatgcttt gagtgaacct ttttttcaat cagagcatgc
    10381 gctgatgccc cacgagttac gtttcttcgg ccctttaagc aatccccttt ggcactggac
    10441 aaaaaagcgt atagtaaata cccgatggat ccccaatgcc ttcaaacacg ctgcacaaaa
    10501 agaaatgctt cctttaccaa aaacaagttt acaaatgatg gatgctgatc taaatctcat
    10561 cacaacgcct aaactatttt tggaagaaga acagctgccg gaaaattatc gaatcgttgg
    10621 tccaattttt gctaagctca gtacttcctt gcctgaagaa gtgctaactt ttatacagcg
    10681 aaagcaacaa gaaagaaaac gtattatcta tttcgcaatg ggtagttcag gcaatccgcg
    10741 tatgttacgc aaaattttgt tcttcttaca aaaacaaccg gatctagcgg ttattgcacc
    10801 tattgactat ctgcttgatg acattcaatc tgactcagaa gatcttttaa taacagaata
    10861 tctgtctagt catcttttgc atgaattcat tgatttttct tttatccacg gcggggaagg
    10921 gaccgtccaa actgcctgtg aatccggcaa accgtttatc ggtgtgggga tgcaatttga
    10981 gcaaagctgt aatattgact attgtgtaaa atacggaaac gcaatcgccc tcacaaaacc
    11041 agtgactgaa agaaaactgc agattgctct gcgcgaagtt tcttcaccca agattcgtca
    11101 gcaggcacgc acgctgcaag ccgtttttcc aataaatggt ccacaacaag caattcaaga
    11161 aatcgaaacc ttcctgagca accacccaat atagtttcaa gtagaaaaag cttttttaat
    11221 agagactcat cagtaatttc gctattcgag acccagacag tgaaaataca aaaaaagtaa
    11281 atagtggatt gaaaagttag agttacttaa attacggtgt ctaaaaaaca caaaatcatc
    11341 cttaaaataa aagatctgac gctatccaaa tgagcatagg tagcgtctgc catttattct
    11401 tagtcaaatt ctttgacacc tttctctggt tggatcatct caacgtttct tcaaaagaaa
    11461 gaccataata attaggcaaa tacattttct taaaatgtgt catatagatc tagaagcatc
    11521 gctttgtaga gatttgtgcc gctagtcccc tcaacaatta ctaaatcaaa tgtaggattt
    11581 accactttat ctttgataat caacctccct cttctgttga gacaatgatc tcgcaatccg
    11641 atgcatactc ctatataaac tgccagcaat ccccacatat tgagtagatc atgtcagaat
    11701 gttctatgtc gtcagcaacg atacactaaa agtcacgttc accatgactg attgctattc
    11761 ccagcacaat tatttctata cacgtttcat gatttgaata aacactcaca tcatacatat
    11821 taccattcat acaccatact gcagccccta ctatatggtt gtaagctccc aaatctatat
    11881 ttgacttgat cactttggta gtagatctac taattctaaa tccattgctg ataaaatttc
    11941 cattttttcc tccttctttc tgccaaaaca gttaaaacaa taataatctt tatgtaaaaa
    12001 agggctgtga caaaagcctt gtcacagtcc catattccga ataaacggtg gtcaaaagct
    12061 tgcatctgcg gtaataagtt caaccaaacg aaaaataagc caacatttca caaaaattta
    12121 agaagcaatt ttcgtaaatt tcttcttatt tcttgaagct aaccacttct gttacaacca
    12181 cttttagaac atttaaagct tcgatgtgac aaaccatcta tgctgctcga tcataaaatt
    12241 gatagcaaaa attccacaaa gtacatatgt cccccatgaa aacaaaacat tcatatgcgg
    12301 tacaatgatc tttggaagaa tcacgatcaa aaatgatgcc agtgcccaaa tccatcgatt
    12361 gatttgaata tgatatgtag ctagcatatt caatataagg tgactagccg ttaataaaaa
    12421 gataaaaaca aaaaataaaa tcagccaata cattgtttcc caccttctaa aaaccaaact
    12481 tagacagtct ggacttcgtt ttctccacga ctttgttcat ctgacagcat ctttttatca
    12541 taagctttta caaatggata atagataata aatgctatca atgtgttgat catgatcaag
    12601 ataacaacac gccagtcatt tcctgctgaa agataaccgc cgattggagc tggtaatgtc
    12661 catgttggca aaacagtaaa tctattgacc atttctaatt tgactgcaaa ataactgata
    12721 atagtcaaaa ctaaaggaac taagttgaac gggatgaaca tgtaaggatt caacatcata
    12781 ggagctccaa aaattatggg ctcattgata ttgaagatac caggaataat agaaaaacga
    12841 ccaacctctt tcaagaattt tgatttacag aagaatataa acaaaacaga taccacgatc
    12901 gttgctcctg caccaccaat tgttaccgtc cattgataaa actgttcagg agcgatatag
    12961 ggtaattggg tggcagctgt accatctgcc aatgcctttg cattctcatc caacatgatc
    13021 agccacattg gacgaacaac agcccctaca atactcatgc catggatacc aaatgaccac
    13081 aacaaatgga tcaaaaacat tggtagtaaa acaccaagca aattattccc taaaatattg
    13141 gttaaaggct cgaataacga taataaggca gcgtttacat caaagcccgc gacgcttcga
    13201 atcagccaag taattgttaa aatgactgca cctggaatca atgcctcaaa actacgggca
    13261 acagcaggtg gcacttgttc tggcattttg atagtaatat ttcgattttt aaagaaacga
    13321 tatacttcca ctgcaaaaat catagataag atccccgcaa acatcccaga tgctcccaaa
    13381 gaactcatag gtaagaccca gccaagaggt gcctcttcag gagttaaaac gtttacagga
    13441 acttgtaaca taaagaacgt tcctaaagat aatataccac ctgtcacact atctaatcca
    13501 tatgatttag ctagatccga acccataaca aaagttgcat aaatagccat caatcccatc
    13561 gtcatcctaa agggtaaaac aatcgttgcc gaataagggg caataaattc attccatcca
    13621 ggaaacggta aattgataaa gaccataaaa aatgtcccaa tcaaaatcaa tgacaatgtt
    13681 gaaacaaccc cattacgaat tgctaataaa tgacgctgtg taccaatttt tgccattggt
    13741 gggacaagtt tctcttcgac ccatttcatc agcttttcca ctaaaaccac tccttttcaa
    13801 taaaatatga accattcatt gcatgacaac gcaaagaatg ttcataacta attatataat
    13861 taagaaattt tatttcaata tattctctta aataatcaaa tttattttta agaatcctga
    13921 aaataagttt tctaaatcat aggagcaaca aaaaaattcg ataattaaca aaaatcaaaa
    13981 tgattaaatc tagtgattga aacatatcat ttcaaaaaaa ttttgtaaat tcacccataa
    14041 atatcaccct atttaacttt tttcatcgta cactaaaatt caaaacaact atctttaatc
    14101 tttacttctt ggttttgttt taataaattt ccttcaaaaa tgcctggaga aactacaatg
    14161 atcaccgtat ctttttgtgc ttgctccaac ttcttcaaat ctataatagc taacagtgtc
    14221 ccttctttta cctcctggtt actttcaacc cgtatctgaa acggacttcc ttcgagttca
    14281 actgtatcta aacccatatg gatcagtatt tttctgccag attcactttc gatcgttatg
    14341 gcatgtcggg taggaaatat attatcgatt attcctttaa ctggcgcatg gatatatcca
    14401 tcatgattcg ttatagcgta tccaactcct atcatttttg aagaaaagac ctcgtctttt
    14461 actgctgtta atggaataat ttgaccacta gctacagctt ttagaatgtt tcttgtttta
    14521 aagaaatgca ctttttatca cctctacttt aatgctggcc aatatttttt gtttactttg
    14581 atcatttcat ctagtatttt ttttgcgact ctggcatttg gtacggtttg attcaatgta
    14641 aatgcttgta aagctttttg ataagaacct tcaaagtaag catctactag taacttctct
    14701 actgcaactt gtgcctccat caatccttta tgaaaatcac tgattggttt tcttagtgta
    14761 attggctcca caccagttgc accaacatat gccggtattt caacaactgc atctgaccgt
    14821 agattcggaa tcgccccttg attaggaacg attagcataa agcgacgacg atcatcattc
    14881 aacaaggaaa tagctatatc gacgatatat tgtccatgct ccccaaaatt aaagttcaat
    14941 acttcttcca caataccgcg gcgtatttta tcagccattt ctttggtatt tttctctcgt
    15001 ccatccatga ccatattagc acgtgtatac tctttgtcag tatgctcaac gaccatatca
    15061 ggatataagt aatactctaa gtaattattc gggatattac ttggaaaatt tttcgtgatg
    15121 actgacatca tttgaaaggt tttttgccaa gttttatctc ctatattaaa atcggcgact
    15181 tgcatttctt ttgttattag tttttcaata atctctggca taatttctcg ttgcaattct
    15241 ttatcataaa tcgatgtata ccagccaaag tggtttaaac cataatacgt aacgatccaa
    15301 ttcttacgat cataaccgta attcactgca atcgtttctt caattgaaat agtcatatca
    15361 caggcattaa tcatttttac attcggatat ttacgacgaa cagcttcaga aacgatcgac
    15421 tctggatttg tataattcaa aatccatgct ttgggggcat agtcttgtat atgatcgaca
    15481 atttccaata aacctttgat tgagcgcatc ccataagcaa atcctccgag tccacacgtt
    15541 tcttgtccta ctaatccatg tttaagtgga atcttttcgt ccttttctcg catctccaat
    15601 cctccaacac gaatttgtga gaaaacaaaa tcgcatcctg taaaagcaag ctttggatca
    15661 tccgttgcac gaatgcgaat atttgaaaaa ccttttcttt tcagcataaa tttaacaatc
    15721 aagtacatat ccatatttct ttcttcatca atatcatata aacgtatttc agataatggc
    15781 aaccgttttt cattgttcaa aatggcttga acgattcctg gtgtatacgt actcccgcct
    15841 ccagctatag tgataatctg ttttttcatc atcatctttt cctttctatt cttctaataa
    15901 tttattgaat tctgccataa cataagtcac ttctaagccg atgataattt gataattttt
    15961 ttcagttggt ttaatgatcc cgcttatccc taattgcttg attcgctgtt cctcgaccat
    16021 ggtgggatcc actacctcta cccgtaggcg tgtattacaa ctatagacat ccaggatatt
    16081 ggcttttcct ccaaacgctt gtagcatttt tgttgccata tattcataat ttttacttgc
    16141 taaccctaac tctgtttctt ctaaggttac ttcattgcca aactctgcct tagcttcacg
    16201 tcctaatgtc tgaatgtttc tcttattgat caaataataa aaagtaacgt aatacaaggc
    16261 aaaaaagaaa attccgattg gaagaatcaa aatagcattg gtagcgattc gaaaattgat
    16321 gagataatca acaatacatg ctccgaatgt aaaaccaatt cgtatattga ataagtaaca
    16381 gacaatccct gctaaaccgg caaaaagtgc atggatcacg tacaacatag gagaaagaaa
    16441 catgaaacta aattcaacag gctcagtgat atttgcaata aatgaagttc ctgcaccgct
    16501 tcccatgatt cctttgacca tctctttatt ttctttataa gctgctttat agatagctag
    16561 acatatagct ggtataccaa acatcattac tacaaaaaaa actgataaaa acagtccagc
    16621 ctgaggatct ccgttgataa agcgtgtcat ctctcctctg aaaacttcct tgctaggaga
    16681 tgtatagctt cctaaatcgt aataaatata cgtattcaac acatggtgca gtccaaaggg
    16741 gatcagcaaa cgattcaaaa acataaatat ccccacacct aatgctccca tatcaacgag
    16801 cagttttgca aaattatcaa tcccaatttg gatgagcggc cagataaagc ccaaaaaaac
    16861 agctgcgatt gtttgtagaa tcatcaccat agtcaatggg aatttttcgc ccgcaaaata
    16921 agaaaaaact actggtaatt tttgttcttt aaagcgatta tacgtccatg ccgctactaa
    16981 accggaaata attccaccaa aaatccccat attcacttct gggtccataa tttctaagcc
    17041 ttttttcaag gtagcaatcg ctaaaaaacc agtaagtgca ggtattcctt tgtccttatt
    17101 tttgacaaaa ccgattgcaa ctcctatagc aaataagata tccaagtttc caaaaacggc
    17161 atttccagct gcaccaatta ctgggatgtt cagcatatcg tcagctgata aacgcatgat
    17221 caatcccgct aatggcatcg ctgcaactgg aagtagcatc gctcttccaa gcttctgcac
    17281 atttgattta acattcattt ttattcctcc tctattaaat atcctcatat gttactaact
    17341 caatcaaagg atcatttttc actttttgag caaatgctga atgaattaaa aattcgactt
    17401 ggtgggtacg aggatacaca aaacttgaac catttaacaa ttcctgatcc aaatacgctg
    17461 cgtgacacat gacttcgatc gttttatctt ctctcaatat catgagtaaa cttgccaaat
    17521 attcttccac actcgtattg atttgtcgtt ttttttcatc agtttctcct acgacatcga
    17581 aacaaggctc aaaataatcg acatgacgaa cttcatcttt tcgttcaaag ttgctccgaa
    17641 ccggcaaatc atattttttt gctaatgtaa caactacctc ctgattttca tccaaagtat
    17701 gagtatgatg atgactgtct aaatgagttg gtatgatccc cgcatgataa attttttgaa
    17761 tctgagcatt ccattcctga tacagttgat ctttgtcaat gttaaatgga tgctgataat
    17821 aagataagga tctgaactct ccgctttcga taagagtatc gacagttttg aggagtggtt
    17881 tgccacacgt caatgttaaa tggactccta cacctagcct aggcatttcc tttcttagtt
    17941 tcacagcatg ctcgaaaccc ggcatatttg ccatcaatgt agttgatgtc aaaattcctc
    18001 gctgataagc atccataatc ccataattca caccatggct atagccaaaa tcatccgaat
    18061 taaaaatcac ttttcccatt tcattctcct tcttttttct actaaaatag gcgcaaccaa
    18121 ataatcatag tccatttact atgtgtcatt tggttgcgcc tatagatagt tacgccctta
    18181 ttttaataga ttcttgctag atgaattgcc aaatagatga tttcattttc ttgaatggca
    18241 agttgaaatt gctgttcgat gatatcttta atctttagtg ctgtacaata cgctttgcta
    18301 tgtttaaatg tttcagtaaa aaaaccaata ttttctactg gcgtttcttc ctgataaatc
    18361 aagcgtttaa ccaggaattt gatatgaacc attaagcgat gataagtcag tgattcttta
    18421 tcataaacgt ttgaatagga tttttctaga tgggacaaaa tcgtggtcgt catttctact
    18481 atttttaagc tctttaaact attaggctct cctagctcag cattaatgat atgcatagtg
    18541 atgaatccta cttcatttga ccctaactcg gtttgatatc gatgattgat tcgctcgacc
    18601 acttctactg ctatatcata ttcatttgga taaaggaatc tcatttctgg caacataatt
    18661 gctgtgacat ctctatcttc tctttttcgt tgaatagcaa aataaatatg atctgtcaat
    18721 gtaatataga tatttgaatc taatggagag gagatcctag ctgttatcag ttcaatcact
    18781 tcttccgcaa aatccataaa ttcgattgga atctgcgaga ctatctcact gaatcgtttg
    18841 atcttttctt tagaatctaa tacaaataat ttgtcagcat cctcaacatc aaatggctta
    18901 ctcactttag cagaaaagcc aatccctttc cccatcgcaa ttttttctat tccatcgtca
    18961 tcgatcaata cagcattatg attcagcttt ttcatcacat acaccgttaa ttcacctcct
    19021 ctatatgata aaacaaaaca acttgcagac tccttcatac atatttttgt ctccaaacaa
    19081 tttttaaaga caaaaaacga cctaagaaag aaccctttct taggtcgtgc ctaattgaat
    19141 agtagcaccc tacataattt acaaaaatag tttaacacat aataaaagcg ttatcaatat
    19201 cttttttact cgttttatga taatacttgt atcgaattga tttggaggta attacataaa
    19261 aacaaaaaaa atatagcaac tctctataag aaagttgcta tattgataat tataccggcg
    19321 gccggggtcg aaccggcacg tcctcaacgg acactggatt ttgagtccag cgcgtctgcc
    19381 aattccgcca cgccggcaaa tttaaaaata ataactgggg tagctggatt cgaaccaacg
    19441 catgagggag tcaaagtccc ttgccttacc gcttggctat accccaagaa taaagggcga
    19501 atgatgggaa tcgaacccac gaatgccgga gccacaatcc ggtgcgttaa ccacttcgcc
    19561 acattcgcca tcataaaaga tgttatttaa tttctcaata aaaaactaag atgaagacat
    19621 cttagtcaat accggcggcc ggggtcgaac cggcacgccc tcaacgggca ctggattttg
    19681 agtccagcgc gtctgccaat tccgccacgc cggcaagttg atttattagt actaaggcgg
    19741 taaccggatt tgaaccggtg atgaaggttt tgcagacctc tgccttacca cttggctata
    19801 ccgccattat actattatca atctataaaa taaagaataa attatagaaa ctggggtagc
    19861 tggattcgaa ccaacgcatg agggagtcaa agtcccttgc cttaccgctt ggctataccc
    19921 caagaataaa aagggcgaat gatgggaatc gaacccacga atgccggagc cacaatccgg
    19981 tgcgttaacc acttcgccac attcgccatg gcaggggcag caggaattga acccacacta
    20041 acggttttgg agaccgctgt tctaccttta aactatgccc ctataaaatg gaggagagtg
    20101 gattcgaacc actgaaccct aaggaacgga tttacagtcc gtcgcgttta gccacttcgc
    20161 tactcctcca tggtggcgcg ggacagaatc gaactgccga cacacggagc ttcaatccgt
    20221 tgctctacca actgagctac cgcgccatat tttaaaatta ttaattgaat aacaagaacg
    20281 acggttccga cgggaatcga acccgcgatc tcctgcgtga caggcaggca tgttaacccc
    20341 tacaccacgg aaccagttca ttatggaggt taacgggatc gaaccgctga ccctctgctt
    20401 gtaaggcaga tgctctccca gctgagctaa acctccaaca ttcaattaaa atgacccgta
    20461 cgggattcga acccgtgtta ccgccgtgaa agggcggtgt cttaaccgct tgaccaacgg
    20521 gccaggtaaa tttgctacgg agagtaaggg attcgaaccc ttgagacagt ttggcaccat
    20581 ctacatgatt tccaatcatg ctccttcggc ctctcggaca actctccaga gtgaaagaag
    20641 ctcaatactc tttctcaaaa tgag
//
LOCUS       DAFEKH010000051        20362 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.053, whole genome shotgun sequence.
ACCESSION   DAFEKH010000051
VERSION     DAFEKH010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.053"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            291..1430
                     /locus_tag="LP386_002137"
     CDS             291..1430
                     /locus_tag="LP386_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HBL1919352.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLARHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHSIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(1497..2072)
                     /locus_tag="LP386_002138"
     CDS             complement(1497..2072)
                     /locus_tag="LP386_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBL1919353.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQVGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(2077..3051)
                     /locus_tag="LP386_002139"
     CDS             complement(2077..3051)
                     /locus_tag="LP386_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HBL1919354.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPVDIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGLDGLGDTNFPMVLAKQAESL
                     HAVDFLTDYFKEKTDTSVIALGPLTNIASALKNSPSVGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFEKLKQPIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIDESICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(3075..3119)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            3334..4302
                     /locus_tag="LP386_002140"
     CDS             3334..4302
                     /locus_tag="LP386_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL1919355.1"
                     /translation="MVIFYFILILIFIGISYHFLSYFYAKKLVRAGVQRGYDWYEETG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGIPKTIKSYDGLKLAGQMFLQPTQQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLIPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPDASIILHGSSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMIMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            4415..4693
                     /locus_tag="LP386_002141"
     CDS             4415..4693
                     /locus_tag="LP386_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBL1919356.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARREGKKIIPSCPYAKKEFEKKPEYHDVLRQS"
     gene            4811..5047
                     /gene="secG"
                     /locus_tag="LP386_002142"
     CDS             4811..5047
                     /gene="secG"
                     /locus_tag="LP386_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HBL1919357.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAVWMILLFVLAFLSSK"
     gene            5150..5905
                     /locus_tag="LP386_002143"
     CDS             5150..5905
                     /locus_tag="LP386_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL1919358.1"
                     /translation="MKRVKQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVETNVPENFEKYVRQVLKIAGKSEKEINEKAVSYRSL
                     AEHQLMDIQDQAAIAESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            5908..8265
                     /gene="rnr"
                     /locus_tag="LP386_002144"
     CDS             5908..8265
                     /gene="rnr"
                     /locus_tag="LP386_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HBL1919359.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILVEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSDEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDIVGRRDLRDQLIVTIDGEDA
                     KDLDDAVTVKKLENGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHEIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILEMMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKSGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            8287..8751
                     /gene="smpB"
                     /locus_tag="LP386_002145"
     CDS             8287..8751
                     /gene="smpB"
                     /locus_tag="LP386_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HBL1919360.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            9053..9772
                     /gene="atpB"
                     /locus_tag="LP386_002146"
     CDS             9053..9772
                     /gene="atpB"
                     /locus_tag="LP386_002146"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HBL1919361.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            9825..10040
                     /gene="atpE"
                     /locus_tag="LP386_002147"
     CDS             9825..10040
                     /gene="atpE"
                     /locus_tag="LP386_002147"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HBL1919362.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            10131..10655
                     /gene="atpF"
                     /locus_tag="LP386_002148"
     CDS             10131..10655
                     /gene="atpF"
                     /locus_tag="LP386_002148"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HBL1919363.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            10642..11184
                     /locus_tag="LP386_002149"
     CDS             10642..11184
                     /locus_tag="LP386_002149"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HBL1919364.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            11207..12763
                     /locus_tag="LP386_002150"
     CDS             11207..12763
                     /locus_tag="LP386_002150"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HBL1919365.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEETLNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            12777..13679
                     /locus_tag="LP386_002151"
     CDS             12777..13679
                     /locus_tag="LP386_002151"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HBL1919366.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            13702..15108
                     /gene="atpD"
                     /locus_tag="LP386_002152"
     CDS             13702..15108
                     /gene="atpD"
                     /locus_tag="LP386_002152"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HBL1919367.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            15122..15544
                     /locus_tag="LP386_002153"
     CDS             15122..15544
                     /locus_tag="LP386_002153"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HBL1919368.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            16013..16243
                     /locus_tag="LP386_002154"
     CDS             16013..16243
                     /locus_tag="LP386_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HBL1919369.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            16340..17641
                     /gene="murA"
                     /locus_tag="LP386_002155"
     CDS             16340..17641
                     /gene="murA"
                     /locus_tag="LP386_002155"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBL1919370.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNCPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            17654..17830
                     /locus_tag="LP386_002156"
     CDS             17654..17830
                     /locus_tag="LP386_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBL1919371.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            17965..18261
                     /gene="yidD"
                     /locus_tag="LP386_002157"
     CDS             17965..18261
                     /gene="yidD"
                     /locus_tag="LP386_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HBL1919372.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            18325..18708
                     /locus_tag="LP386_002158"
     CDS             18325..18708
                     /locus_tag="LP386_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1919373.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASNQTRIIIRTGTTS
                     SAALHLYQKMGYVEIGRVKDYFIHH"
     gene            18877..19761
                     /locus_tag="LP386_002159"
     CDS             18877..19761
                     /locus_tag="LP386_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL1919374.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKTQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLD
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            19875..20111
                     /locus_tag="LP386_002160"
     CDS             19875..20111
                     /locus_tag="LP386_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HBL1919375.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            20199..20279
                     /locus_tag="LP386_002161"
     tRNA            20199..20279
                     /locus_tag="LP386_002161"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20233..20235,aa:Tyr,seq:gta)
     gene            20286..20357
                     /locus_tag="LP386_002162"
     tRNA            20286..20357
                     /locus_tag="LP386_002162"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20318..20320,aa:Gln,seq:ttg)
BASE COUNT         6760 a         3567 c         4425 g         5610 t
ORIGIN      
        1 ttttttgcaa ctagcttctg tatatgatgt ttacaaagaa tggtacaaga aaagatcatc
       61 cttgaaaaag gaaagctaac aataactagc atcatataag agcttttaag gatagaacag
      121 tagaatagga atctatgggc aagtcctctc gtataaataa aataggaggg aagtagcagc
      181 atatttttca taaagtggct ctctttcttc atttttactt tggttgctcc tatttgaaaa
      241 ttcgagcaca ctcaaataca ataaaaagaa atggcaaggg agaggattag atgaaaaaag
      301 aagaaaaaat cgcgatttta caagagatta tccgaattaa atcagtgaat ggaaacgaag
      361 gtgaagtagc agcctatttg aataagcttt tggcaaggca tgacataaca ggagagattg
      421 tttcttacag agatggtaga gataatttga ttgctcgtta ccaaaagggc caatcaggaa
      481 aagtgttagg cctatctgga catatggatg tcgtggcggc tggtgatgaa tcgtcttgga
      541 cctatgcacc ctttgcagca gaaatccatg ggaaccgttt gtacggacgt ggtgctacag
      601 atatgaagag tggcttggca gcaatggtga ttgccatgat cgaactgaaa gagtcaggaa
      661 aaccatttaa cggaacagtc aaattattag ccactgtcgg agaagaagtg ggtgaactag
      721 gtggggaaca gctcacgaaa gcaggctatg tagatgactt agatgccttg atcatcggag
      781 agccaaccaa ttacagtttg atgtatacgc acatgggatc aatcaactat acagtcacct
      841 cgcacggaaa agaagcgcat agctctatgc cagaccaagg ttataatgca atcaatcacc
      901 taaatgaatt cattacgaaa gcaaatgctg aaatgaatca cctcgctgaa acaatcgaga
      961 atcctgtcct aggaaaaaca atccataatg ttacattgat cagtggcggg aatcaagtca
     1021 acagcatccc aagccatgcg cagctccaag ggaacattcg atcgattcca gaatacccaa
     1081 atgataaaat cattgcattg ctgcaatcaa tcgtcaatga attgaatcaa gagacagact
     1141 atcatttgga attgatgatc gattacaaca aaatacctgt caaagctgat ccagattctc
     1201 ctttgattca ttccattcag caacaattca gccagccatt acctttagtt ggagcggcag
     1261 caacaacgga tgcagccgaa tttacgaaag ctaaccattc cttcgacttt gtcgtctttg
     1321 ggcctggtgt cgttactttg cctcatcaag tagatgagta tgttgaaatc gataattatt
     1381 tggatatgat cgaaaaatat caaggaatta ttttatccta cttagcgtaa gattttttta
     1441 ataaatgaaa aaacagagcc agattagcat tattttgcta atccagctct gtttattcag
     1501 cctatttttc tttttgaata tatcaagcgt tggggcaaca tagtgatgac taatgaaaca
     1561 acgacgatag acaacaagcg atcaaggtag tctgtaccca cctgtaccaa gatcacactt
     1621 gttgtctgac ttaaacctaa cccatgtaat agctgaacga tcatactgga tcctgaggag
     1681 gtgatcccgc caaataactg aacggtaatg atcgaagaaa cgatcgttcc aggtaccgac
     1741 aaaatcaaag cgagtaataa cagtttcaag ctgtttttat ctttgccgag atatcttggc
     1801 aaaatcaatc cagcaagcaa gcctgtgaga atttggattg gcgaataata cagagaaaaa
     1861 atatctgtag tcactccact taaaataccg ctggacaatc ctgtcagcat tccaggtaca
     1921 ggcccaagca atgcaccagc aaaaatcgtt ccgatagaat cgagatagat tggcaaacga
     1981 agccataaag caatcgttcc tccaatataa ttgatcccaa tacacaaagc catcactgta
     2041 agtacgcgag ttgccatttt gtttttattc attttgttag cccatcttta acctttccaa
     2101 atctttcata atcgtttctt cttgtgcatt taaaagaacg gttaaaaact ttcggaaaaa
     2161 aagacgagta tctacttttg tcataatttt actgttagca ggtttctgcc aaaattcata
     2221 acgatcaacc aatgtttgtc cgcgacttat tccttgagtt tctacagcag tgaagctttt
     2281 aaagccttca cagatggact catcgataaa ataagcaaca gctaatggat cattgatgac
     2341 acatcctaag attctttctt gtttccagtg aaagtcaaaa taaaaacgag tgatcgcttt
     2401 tagatactct ccctcttcag gattcatttg gcagcaatat tcaaggatag tcggtgtcaa
     2461 gacgatttct cttgtcacat ctaacccaac catttctatc ggttgtttga gcttttcgaa
     2521 tacataagaa gctgcttcag gatcacacca gtaattgtat tcagcaactg gtgaacagtt
     2581 accatggctt ttgtaagttc cgcccattga gacaaaacga tccatatgtt tcccaacaga
     2641 tgggctgttt ttcaaagcag aagcgatatt ggtcaaaggc cccaaagcaa tgactgatgt
     2701 atctgttttt tctttgaaat aatcagtcag aaaatcaact gcatggagcg attctgcctg
     2761 tttggctaag accatcggga aatttgtgtc ccctaatcca tccaacccat gagtgtcttg
     2821 cgcactaatg aaaggttgct tcaaaggttt ttccattcct tgataaacag ggatatctaa
     2881 acgatcacag cgctccaaac atttcagcac attctgcgta ccgatatcta cagggacatt
     2941 cccgcaaacg acggtaatag caactacttc gatatcaggg gatttgacag ctagtgataa
     3001 agctaaagtg tcgtcgatcc ctggatcgca atcaataatt actttacgca ttatttccaa
     3061 tctcctttct ttagagatac ttagtttttt attctgggaa gtttccgaac cagtccaaga
     3121 cgagtgtctt gtttataatg cacgaaatta gtatactggc ttttattgtg aatgtaaatg
     3181 ctctcttaca agtaaatcta ttgagaagaa ctttaagtaa atgatacaat gaaaaagaaa
     3241 tggaatttac gtgtgccgaa gaaaaagaat cctattgatc ggtatattgt ataataaata
     3301 gattatagtt tggcagaaag cggcgggtgt acgatggtta ttttttattt cattcttatt
     3361 ctgatattta taggaatcag ttaccatttt ctttcttatt tttatgcaaa gaaattagta
     3421 agagcggggg tacagagagg ctatgactgg tatgaagaaa ctgggcaccg cttgatggat
     3481 cctgctgcag tcacgtcagt agaaaaaaag cgacaaaaat tagaagaaga gtgtgaaagc
     3541 ttctgggaac aaggaatacc gaaaacgatc aaaagttatg acgggttgaa actagctgga
     3601 cagatgttcc tccaaccaac tcagcagaat aaatgggtca tttgtgtaca tgattatcga
     3661 agtacaggga aaagagatat gtctcatata ggtaaaagat atgcagagaa aggattcaac
     3721 gttcttatac ccgatttacg tgcgcatgga gaaagtgaag gagaaatcat cggaatggga
     3781 tggctagacc ggctagattt aattgcatgg atccaactca tcttagatga acaaccagat
     3841 gcatccatta ttttgcacgg cagttcgatg ggcgcttcta ctattatgat ggcaagtggt
     3901 gaaaagcttc catctgcagt caaaggattt atcttagaca gcggatatgt ttctgtttat
     3961 gcggaatttc ggtatatgtt aagtaaaatc acggtctttc ctaaaaaaat gatcatgaga
     4021 tatgcgaatc actatgctca gaaatacgca ggttattctt taaagcaagc atcagctaca
     4081 agacagcttg gtagtaacca tttgcctttg ttagtcatcc atggtgaaag agatcatttt
     4141 gttcctacag aagcagcata cacgattcaa aacgctacgg caggggataa agcattactg
     4201 cttgttccag aagcagaaca tttggaagca tcgatgaaag atccgaaaac ctattggaca
     4261 gtgatttttt catttattga acaaagaata acgatggatt gattttctct tcctttttgt
     4321 aagcaacacg aggataaata attgtttata gaccatgaga ctgttaaaat aaggtaggaa
     4381 taaaaaaata tcagttattt gaggagtgcg gcatatggaa atcaaagagg aaaaaaatcg
     4441 tcttgcttta ttcaatgatg agcaacaaga aatcggagaa atgacatggt cggatgcggg
     4501 gccagacatc atgatcattg accatacatt tgtcgatcca gcatatcgtg gtcaaaaatt
     4561 agctgaaaag ctagtgtata ctggagtaga actagcaaga cgagagggga aaaagattat
     4621 cccttcatgc ccttacgcaa aaaaagagtt tgagaagaaa ccagagtatc atgacgtctt
     4681 acgccaatca taataataac agctgaaaga tttgcacttt cagctgtttt tccatttata
     4741 tagagttgtc acggagtttt atctatgata aagttaaaga gacgatatct tttgggaagg
     4801 aggctgctat atgtataatt taattttggg aatcgtgatc gttttatcga ttgttatggt
     4861 cattgcgatt atgatgcagc caagcaagca aaatagtgca gcgagtgcat ttaccggcgg
     4921 tgcggatcaa ctattcggca aacaaaaagc tcgcggcttt gaagctgtca tgcagcgatc
     4981 aactgcagtc atgggagctg tctggatgat cttattattt gtcctagcat ttttatcttc
     5041 gaagtagtcg aataagcctc tcgcacaacg gcgggcggct ttttttattg caaagagaac
     5101 gcttaagaag aagttatgaa agaaactatg gtaaaatgag gcgaaagagg tgaaacgagt
     5161 gaaacaatta ccaaaacccc tttatgcaaa acatggaaaa cgagcagttt tgctgcttca
     5221 tgcgtactca ggaagtccaa atgatgtccg gatgctcgca cggtttttag aaaaagcaga
     5281 ttatacagtc tatgcgccgc tatttaaagg acatggaacg atggagccat atgatatctt
     5341 gcaagaaaaa gcagaaagct ggtgggcaga tactaaaaaa gctatccatt ttttacagtc
     5401 tgaacagttt tctgatattg ccgtattggg attatcgatg ggtggcatct ttgctgtacg
     5461 ggcactagaa gaagaatcag taattggcgg cggttttttc tgttcgcccc tgtctcctgt
     5521 agaaacaaac gtgcctgaaa attttgaaaa atatgtacgt caagtgctga agatagcagg
     5581 caaatcagaa aaagaaatca atgaaaaagc tgtgtcttac cgctcgttag ctgaacatca
     5641 attaatggat atacaagacc aagcagcaat cgcagaaagt agactatcag atatccaaca
     5701 gccaatattt ttagctcaag ctgggaaaga tgaaatgatc gacccaaatg gtgtatttga
     5761 aacggcacgc aaattgagcc gccaacgagt gacacttcaa tggtatcctg aaagcggtca
     5821 tgtgattaca gttggcacag caagacgcga attagaaaaa gacgtgttgg aatttttaga
     5881 aaaattacct tggaatgagg aataaatatg acaaaagaaa caataaaaga gaaaattctc
     5941 tttttcatgg aaagcagtcg caaacgtagt ttttctatgg aagaaatcgc tgaaggtcta
     6001 ggctttcaaa aaagcgatga ttttaaatta ctagtacaaa cgattgctca aatggaaaga
     6061 gaacagagta tcgttttcaa taaaaaagga aaagtcaaac ttcctttaaa accgatcttg
     6121 gtcgaaggga catttcgggc aaatgaacga ggatttggat ttgtaacgat tgatcccgaa
     6181 gaagatgata tctatatccc gaaagaagcg actggctttg caatggatgg ggataccgta
     6241 gcaattgata tcatgaagcg agcaaataca gatatggatc gcggagcaga gggaaaagta
     6301 gtggagattc gagaccgagc gactactcag ttagccggag aatttgttgc ttattcagac
     6361 gaagagatac aggaaacgga tctttatggt gtggtcatcc cgaaagatag aaagcttaac
     6421 caattcaaag tgtatgcagc ggcagaggga gttcgtccag ttgacggaag tattgtattg
     6481 atcgaactga cccattaccc tgaaaaaggg tatgcaacta gtttagaagg gataatcaag
     6541 caagtgattg gtcataagaa tgaccctggc atggatatcc tctcgattgt cgtggctaac
     6601 ggtattccta caaaatttcc tgatgatgtg ttatctgagg cagatgaagt tccagaccag
     6661 atcagcgaaa aggatattgt tggacgcaga gatttaagag atcagctcat cgttacgatt
     6721 gatggagaag atgcaaaaga tctagatgat gcagtgacgg tcaaaaaatt agaaaatggt
     6781 aattattttc ttggagtaca cattgcagat gtatcttact atgtgacgca aggcagtcaa
     6841 ctggacagag aagcatacga aagaggaaca agtgtctatt tgaccgatcg agtgattccg
     6901 atgatcccac aacgtttatc caatggtatc tgttcattga atccccatgt tccacgactc
     6961 accatgagtt gtgaaatgga gatcgatcca aatggacaag ttgtctctca tgagattttt
     7021 ccaagtgtga tccaaacaac agaacggatg acctacacag ctgtcaatca aatcttagaa
     7081 gatcaagatg aagaaacgat gcaacgttat gctcagctcg tgcctatgtt ccaagaaatg
     7141 ggtgaattgc atcgaatcct tgaaatgatg cgaatcaaac gtggagcgat ttcttttgag
     7201 gatcgtgaag cgaagatcct tgttgatgct gaaggacacc caaatgatat ccagctaaga
     7261 agcagaggga taggtgaacg cttgatcgaa tcctttatgc ttgctgccaa cgaaacggta
     7321 gctgaacatt ataataaatt aaatcttccg tttatttatc gaatccatga acagccaaaa
     7381 gaagaaaaaa tgcagcgctt ctttgatttt gcttcagctt tgggcattct ggtccgagga
     7441 acgaaaggaa cgatcacacc aaaagattta cagcatgtga tcgaaggagt agaagacaaa
     7501 ccagaagctg cagttatcaa tactatgttg ctaagaagca tgcaacaagc acgctattca
     7561 gaagacaatt ttgggcatta tggcttagcg gcagattact acacacactt tacatctcct
     7621 attcgacgct atcccgatct aatcgtccat cgtctgatcc gttcttacag tgaagataaa
     7681 agtgaaagca atcaaagttc gtgggctgcg gaacttcctg aaattgcaga tcatagttct
     7741 aagatggaac gtcgtgcagt agaaacagaa cgtgaagtag attccatgaa gaaagcagaa
     7801 ttcatgatgg acaaagtggg agaagaattc gatgggatca tcagctctgt tgtgaaattc
     7861 ggcctgttta tcgaactgcc gaatacagta gaaggattga tccatatcaa tgaattgaaa
     7921 caggactact tccattttgt tgaaaatcat ttagctcttg taggtgaaag aactggtctg
     7981 acttttaaaa tcggacaaaa agtgcgcgta aaagtagtca aagctgatcc agatgaacga
     8041 gcagtggatt ttgaactcgt ttccgcagaa gaggtcactg cgttggaacg tccaaaagca
     8101 cgcaatggaa aatctggaaa acgagaagga aaacaagcag gcaaacgctc agaaaaaaat
     8161 ggcaagaaga acaaacgata tagtgatagt aagcaaacgt tcggtaagaa aaaagggaaa
     8221 aagccatttt acaaaggtgt caaaaagaag aaaaagaaaa aataaaatga gttggaggaa
     8281 acagctatgc caaaaggcga gggaaaacta attgcacaaa acaagaaagc tcgccatgat
     8341 tattcgatca tcgacacgat ggaagcaggg atggtcttgc aaggaacgga gatcaagtcg
     8401 atacgaaaca gccggatcaa tctgaaagat ggatttattc gcgtccgcaa cggggaagct
     8461 ttcttgcata atgttcatat cagtccttat gaacaaggaa atatttttaa tcatgatccg
     8521 ttgcgcacga gaaagttatt attacacaag aaacaaatcg ttcgtcttga aaacgaattg
     8581 aaaaacactg gaatcactgt tgttccttta aaagtctata ttcgtaacgg ctatgccaag
     8641 gtattgattg gtctggcaaa agggaaaaaa tcgtatgata aacgggaaga tttgaaacga
     8701 aaagatatcg atcgacaaat tgatcgaaca ttaaaaaatt tctctagata atttcattat
     8761 cctttttcgc atattcggtg cttttgcttt tacttaatga taaaatttgt tagcatttaa
     8821 tctgataaaa catgattatc acaggttttt tcttagatca ggagcaccgt gcatggggaa
     8881 aaattcgctt cgtttttgac tgaaataaaa aagtgtctaa ttttcatgaa aatgttttga
     8941 attttctgtt tcatggtggt atgataccgt gtggttagaa accgattgga aaaaaccaga
     9001 tacgcacatg aattgatttt atgtgaattt cggggaaaag aggtgaaatg gattggatga
     9061 acgctcgcta acgtttcaca ttggaccaat ttggtttgat ggtacagttt gtataatggt
     9121 gttactgacc tgtttgattg ttttcttctt agcttacttt tttacaagaa atcttaagtt
     9181 gaaaccaaca ggcaaacaaa atgcgataga atgggtcatt gattttagtc gaggaatcgt
     9241 aacagataat ctgcctagaa aagaattgag caatttccat ttgttggcat ttacattgtt
     9301 tttatttgtt tttgttgcaa acaacatagg tttagtaaca aaaatcgtct tacctaacga
     9361 aacaacactt tggaaaagcc cgacagcaga cccgtttgtt actttaactt tggcatttat
     9421 aatgatctta cttactcact tattcggggt gaaaaagtta ggcttcaaag gatatttcgt
     9481 aaattcgttc ttgaaaccct atagttttat gtttccgatg aaactgattg aagaatttac
     9541 aaacttatta acacttgctt tacgtcttta tgggaatatt tatgcggggg aagttttgct
     9601 aaccttgatt gcaaaaatga tgacaagctt aggctggttc tcattaccat tagcaattcc
     9661 attagagatg gtctggatcg cgttctcctt gtttattggg agcatccaag catttgtctt
     9721 tgtcactttg tcaatggttt atatgagcca taagattgaa gtagaagaat aatactcggt
     9781 taaaaaacaa actactattt atctatttta ggaggaaaac aattatgaat tatatcgcag
     9841 cagcaatcgc aatcatggga gcagcaatcg gagccggtta tggtaacggt caagttatct
     9901 ctaaaacaat cgaatcaatg gctcgccaac ctgaaatgtc tggtcaattc cgtacaacaa
     9961 tgtttatcgg ggtagctcta gttgaagctg ttcctatctt aggggtagtt atcgccttga
    10021 ttctagtttt tgccgtttaa ttgaatcagt attaaggcag aaacaacatc gtttgttact
    10081 gcttttttac atggaaacta gaaatactcc aaagaaagga aggctcgcct atgctgaatc
    10141 aattggcaat tgcagaagtt ggcaatgcga tgttaggtaa tatcatcgtt gtcagcggct
    10201 catttttgat actactggct ctcttgaagc actttgcttg gggaccaatc agcgatattt
    10261 tgaaaaaacg tgaagacaag atcgccaatg atttagattc tgcagaacaa tctcgcatca
    10321 actcagcgaa aatggaacaa gaacgcgaac aacaattgtt agcctctcgt tctgatgcag
    10381 ctgatatcat caaaaatgcg aaagaaagtg gagaattaag ccgccaaaat attttgaagg
    10441 atgctcaaga agaagcagct cgtctaaaaa gcaaagccca agctgatatc actgtagaac
    10501 gtgattcagc gctgaactct gtaaaagacg acgttgcaga actctctctt caaatcgcgg
    10561 aaaaaatctt gaacaaagaa ttatctccag aaatgcatga atcattaatc aatcaataca
    10621 ttgaaggtct aggttcttca aatgaaacta gataaatata cagtaggaag acgttacggg
    10681 aaagctttat ttgaactggc gatcgattca aatcaagcag aagaaatcta tcaagatctc
    10741 gtaagtttac gtcaaatcta tgaacaagta cctggattag ggaatatgtt aagtgatgtt
    10801 cgtctagaac ctcatgaaaa acgagaaatc atggacaagc ttgtcagcgg ttatgatgga
    10861 atcgttaaaa actttttaga agttgtttat gagtataacc gaatggatga ccttttgttc
    10921 atgattgaag aatatgaacg tcgatatgat gaacatcaag ggttactatt gggaagtgtc
    10981 acaacagcag tcccactttc agacgaacaa cgaatacaat tagaaaagaa tgttgcaaaa
    11041 acaatggact atcaatcagt tgaattaaaa caaatcgttg attcttctat tattggtggc
    11101 gcgattgttg aagccaacca tcgagtaatc gacggaagca ttcgcacgca attagaaaaa
    11161 atgcgtaatc aattaaacag atagtacaaa gaggtaggtg aatcgaatgg ccatcaaagc
    11221 agaagaaatt agtgccttga ttaaagaaca aattgaaaat tatcaaaacg tgctttcagt
    11281 cgaagaaatc ggtaccgtaa cttatgtagg tgacgggatc gctcgtgcac atggtttaga
    11341 aaacgcgatg agtggtgagt tgcttgaatt ttcaaacggc tcatacggaa tggcgcaaaa
    11401 cttagagtca aatgatgtag gtatcattat ccttggcgat ttcgagtcca ttcgtgaagg
    11461 agataaagta aaacgaacag gtaagatcat ggaagttcca gttggagagg ccttgatcgg
    11521 tcgggtagtc aatccgctag gtcaaccaat cgacggacta ggtgaaatcg ttactgacaa
    11581 agctcgtcca gtagaagcga tggcaccagg tgttatgcaa cgtaaatctg ttaacgaacc
    11641 aatgcaaaca gggctaaaag cgatcgacgc ccttgtgcca atcggacgcg gacaacgtga
    11701 attagtcatc ggtgaccgta aaacagggaa aacttctatt gcgattgata cgatcatcaa
    11761 ccaaaaaggt caagatatga tctgtatcta tgtagcaatc ggacaaaaag attctacagt
    11821 tcgtacacaa gttgaaacat tgaaaaaata tggcgcaatg gattacacaa tcgttgtgaa
    11881 tgccggtgcg tctcaaccag caccattact ttatatcgca ccatatgctg gtactgcaat
    11941 gggtgaagaa ttcatgtaca acggtaaaca tgtattgatc atttttgatg atctttcaaa
    12001 acaagctgtt gcttatcgtg aactttcctt gctacttcgc cgtccaccag gtcgtgaagc
    12061 ttatcctggg gatgttttct acttgcactc acgtttatta gaacgtgcag caaaattaag
    12121 tgatgatcta ggcggcggtt caatgactgc tttgccattt gttgaaacac aagctggaga
    12181 tatctctgct tatatcccaa caaacgttat ctcaatcact gacggacaaa tcttcttaga
    12241 aagcgacttg ttctacgcgg gtactcgtcc agcggttgat gccggactat ctgtctctcg
    12301 tgtagggggt tctgcgcaaa tcaaagcaat gaaaaaagtt gctgggactt tacgtctaga
    12361 cttagcaagt tatcgtgaat tagaagcatt tacacaattc ggttctgatt tggatgcggc
    12421 aacacaagca aaactaaatc gtggacgccg tacagtagaa atcttgaaac aaaaactgca
    12481 tgcaccgcta gctgttgaga aacaagtagt gattttgtat gccttgacac atggattctt
    12541 ggacagtatc cctgtagaca gtattttaga cttcgaacat gaattattcg aatatctgga
    12601 taccaatcat tcagatattt ttgaaacaat ccgtacaaca aaagatcttc cagaagaaga
    12661 aacgttgaac agtgcgattc aggaatataa agacatgttc ttagctacaa aaggaaataa
    12721 ttcctctaca gaagataaat tgaaatccat tcaaaatgca tagtgaggtg agatgaatgg
    12781 gtgcttcatt aaatgaaatc aagacacgta tcgcttcaac gaaaaaaacg agccaaatca
    12841 cgcgggcaat gcagatggtg tctgcttcta agttgacaaa atctgaagct tcttcacaga
    12901 agtttcaggt ttatgcaaca aaagtaagag aaatcgttac gcatttgact gctactcagt
    12961 taaatgatat tgcctcagaa aatcctagag gggatatcaa ttacaacagc atgctgctca
    13021 gccgtcctgt gaagaaaacc ggttatatcg tcatcactgc agatggcggt ctggtcggtg
    13081 gatataacag ttcgatattg aaacaaacga tgtctatttt agaagaagac caccaatcac
    13141 ccgatgatta cgtgatgatc gcaattggcg gaactggtgc agacttcttt aaagcacgcg
    13201 gtatcaacct agcatatgag ctgcgcaatt tatctgatca gccaagcttt gatgaagtcc
    13261 gcaaaatcgt aaatatggca acaactatgt accaaaacga agtattcgat gaattatacg
    13321 tatgttataa ccatcatatc aattcgctaa ctagtcagtt tcgtgtagaa aaaatgctgc
    13381 caatctcaga cttagatcca gaagaagcaa cgactttcga acaagaatat atttttgaac
    13441 cttcaaaaga agaaatcttg tctcagttat tgcctcagta tgctgaaagt ttgatctacg
    13501 gtgcgatcgt tgacgccaaa acagcagaac atgctgctgg tatgacagca atgaaaacag
    13561 caactgataa tgctgctaat atcattgatg agctgacggt ttcttataac cgtgcaagac
    13621 aaggggctat tacccaagaa attaccgaaa ttgttgccgg agcttcggca ctagaatagt
    13681 attgagattg gaggaaaaaa gatgagttca ggcaagattg ttcaagtaat cggtcccgtt
    13741 gtcgacgtgg aattttcttt agaccaatcc ttaccagata tcaacaacgc attagttgtt
    13801 tataaaaatg acgaaaataa atcaaaagtt gttcttgaag cagcgttaga attaggggac
    13861 ggagtgatcc ggaccattgc gatggaatca acagatggtt tacaaagagg aatggaagtc
    13921 attgatacag gcaaagcaat ctctgttcct gtaggtaaag aaacattagg tcgcgtattc
    13981 aacgtactag gagatacgat cgatttagaa acacctttcc cagaagatgc ggaaagaagc
    14041 gaaattcata aaaaagcacc agcctttgac gaattaagta caagtacaga aattttggaa
    14101 acagggatca aagttatcga tttgcttgcc ccatatttaa aaggtgggaa agtcggacta
    14161 ttcggtggtg ccggtgttgg taaaaccgta ctgatccaag aactgatcca taatatcgcc
    14221 caagaacatg gtggtatttc tgtatttacc ggtgtaggtg aacgtactcg tgaaggtaat
    14281 gacttgtatt atgaaatgaa agattcagga gttatcgaaa aaacagccat ggtgttcgga
    14341 caaatgaacg aaccaccagg tgcacgtatg cgtgttgctt tgactggttt gacgattgcg
    14401 gaatatttcc gtgatgtaga aggtcaagat gtactgttgt ttatcgacaa cattttccgt
    14461 ttcactcaag ctggatctga agtatcagcc ttgttaggac ggatgccttc tgcggttggt
    14521 tatcaaccaa cattggcaac agaaatgggt caattgcaag aacgtatcac atctacgaaa
    14581 aaaggttcga tcacatcgat ccaagcaatc tatgtgccag ccgatgacta cactgacccg
    14641 gcgccggcaa cagcattcgc ccatttggat gcgacaacca acttggaacg taaattaaca
    14701 gaacaaggga tttatccagc ggtagatcca ttggcttctt cttcaagtgc tttagcacct
    14761 gaaatcgtgg gagaagaaca ttataaagta gcaacagaag tccaacacgt attgcaacga
    14821 tatcgtgaat tacaagatat cattgctatc ttaggtatgg atgaattatc cgatcaagaa
    14881 aaagtgttag tttctcgtgc ccgcagagtc caattcttct tgtcacaaaa ctttaacgtg
    14941 gctgaacaat ttactggtct tccaggttca tatgtccctg tagaagaaac agtgaaagga
    15001 ttccgcgaaa tcttggaagg caaatacgat gatcttcctg aagaagcttt ccgaagtgtt
    15061 ggccgaatcg aagacgtcgt agaaaaagcg aaaacactag gctactagaa aggggtgccc
    15121 catggatcaa tatttaacag taaatgtggt aactcctgcc ggtttggtct atgatcacca
    15181 tgcagctatc gtcgttgcac gtacgacagc tggtgagctt gggattttgc ctaaacatgc
    15241 accaatcatc gttccattga cgattgatga agttcgtgta aaacgaacag attcagatac
    15301 ccacgtcgat tggatcgctg ttaatggcgg aatcatggaa gttcgtgata atgttgtttc
    15361 aatcgttgct gatagtgcgg aacgtgaacg tgatatcgat gtatctcgtg cggaacgtgc
    15421 aaaacaacgc gcagaacgcc aaatcgaaga agcaaaagca aaacaagata cgaacgaatt
    15481 gaaacgggca actgttgcgt tgcaccgagc aatcaatcgt atcaaagtat ctaagcactc
    15541 ataaaatgag atgcggatgt ttatccgtgt ttaagaacag taaaaagagg ttatgacaga
    15601 agtggtcagc ttcaagacat aagaaggaat ttacgaaaat tgcttctcaa atttttgtga
    15661 aatctcagct tatttttcga agaagctact tctggaacac cgtatatcag aggttgtgaa
    15721 atcagcgttt tgtcctgagt attagagaaa caaatggaaa atagttcctc atattttgcc
    15781 gttttttgag ctaataccga gggtcagatg attgaacacc gtttatttgg aataagggac
    15841 tgcgacaaga cttttgtctc agtccctttt tttgcatatt tttagcattt atttcctaaa
    15901 aaatgtaagg ggattcctat atttttaagt atacttgttt ttccttttat acattttatg
    15961 gtattatcat tttattagtt attataaaac aatcgttaga aaggacgtca ttatgcaagt
    16021 atacggaatt gatgcggtgc ttcgaatcgt gagtcatttg gcgtttatct acttagcctt
    16081 ctggtcttta cgttcgttac gcattgaaac ttttttcaga ccaatgcata atacgcaaat
    16141 tagaatggca atcgtacttt tttcaatttt tttagggtac actgcaagta attttttctt
    16201 agaagttatc gctttatgcc gaaatctttt cgttagcctg taaattttaa aaaaaggtac
    16261 tattttaaaa gcaaggatgt tataatagaa aagattttga gtaagtgtat gctcattgga
    16321 attttttgga gggaacaaca tggaagagat catcgtaaga ggtggcaatc aattaaatgg
    16381 aacagtaaga attgaaggag ctaaaaatgc tgttttgcct attttagctg ctagtttgtt
    16441 agcagaagaa ggtattacga cattagacaa cgttccgatt ctttctgatg tcttcactat
    16501 gaatcaagtg attcgtcact taaacgtaga tgtagatttt gatgaacaaa agaatcaagt
    16561 aacaatcgac gcttcaagac aattagaaat cgaagcgcct tatgagtatg ttagtcaaat
    16621 gcgtgcttca atcgttgtga tgggtccgct acttgccaga aatggacatg caaaagtagc
    16681 tatgcctggt ggatgtgcga ttggtaaacg accaatcgat ttgcatttaa aaggatttca
    16741 agctttagga gcaaaaatta ttcaaaaaaa cggctatatc gaagcaattg cggatgaatt
    16801 gatcggtaac acgatttatt tagatttccc tagtgtgggt gctactcaaa atatcatgat
    16861 ggctgccgta aaagcaaaag gaacaaccat cattgaaaac gtagctcgcg aaccagaaat
    16921 cgttgattta gcaaacattt tgaataaaat gggcgctcaa gtctatggag ctggtactga
    16981 aacaatgcgt attgaaggcg tggatcattt acatgcagtc aaccactcaa tcgtacaaga
    17041 tcgtatcgaa gcaggtacct ttatggttgc tgctgcaatg acacaaggca atgtgctgat
    17101 tgcagatgct atctctgaac ataactgccc attgatttct aaattgatcg aaatgggtgc
    17161 agaaatcatt gaagaagaag gcggagtccg tgtcatcgga ccaaaacata tcttacctac
    17221 agatgtaaaa acgatgcctc atcctggttt ccctacagat atgcaagctc aaatgacagc
    17281 tatccaatta gttgcagaag gtacaagtgt ggtgactgaa acagtgtttg aaaatcgttt
    17341 ccaacattta gaagagatgc gccgtatgaa cgctcatgtc aaaatcgacg gaaatgtagc
    17401 aatcatggat ggaaaccatg aattgcaagg tgcagaagta tatgcaacag acttgcgggc
    17461 agcagcagca ttagttttag ctggcttgaa agcaaatgga atcacacgtg tgcgtaactt
    17521 gaattatcta gaccgtggat attataattt ccatatcaaa ctacagcaat taggtgcaga
    17581 cgtcgaacgt gtagacatgg atcaaacttc tgctgaaaaa acagcacaaa cgattgctta
    17641 aggaagtggc tgaatgagta accaacgata tatcttatta actttgataa agattttagt
    17701 ggtgatctta ttgcttatcc ttctttttgt ggccggaacg atgatcggat atggtgtcat
    17761 cggtggcggc aatccattta aagtattcca gccaagtttg tggattcata ttcgagactt
    17821 ttttcattga taaataagaa tcacagtggt tctagtcgat atgaagtgag ccatgaagca
    17881 gaacatgata aaagaaaaca gaagggaacg ttgacgttag tcgcgatccc tttttttagt
    17941 aaaagaaaag aaggaatcta attgatgaag aagatattga tttatttagt tagaggatat
    18001 cagcgcttta tttcgcctgc atttccacct agctgccgtt attacccaac ctgttccaat
    18061 tatatgataa aagcaattca aacccatggt gcgctaaaag ggacggtaat ggggactgca
    18121 cggatcttac gctgtcatcc ttttgtcaaa ggcggtatcg attatgtacc attgacattc
    18181 cgattaacgc gaaataagaa agataaaaaa gaaccagatt ataaaaaggt tgtgaaaaat
    18241 acgggtagca ctgagcgata aagaaaaaga ggaaatttat tgtcaaagta acaactccgc
    18301 aactacttat atgggggaca aaaaatgatc gaagaactaa acaagaaaga tttaccatgg
    18361 tccttgttat tagatgcaga tcctgataaa gaaaaagttc aagtatatgt ttccagaggg
    18421 agtggctgga tatggaaaga aaaagaaaaa acaataggtg tactgatcta tgtggcaagg
    18481 gaaaaagaat acgaaatcgt caatgtagca gtaaccccaa cgtatcaagg aaaggggatt
    18541 ggcggaaaat tacttgagac agcttttcag aagctttcac agctagcttc aaaccaaact
    18601 cggatcatta tacgtactgg cactactagt agcgctgcgt tacacctcta tcaaaaaatg
    18661 ggctatgtgg agattggtcg agtcaaagac tattttatcc atcattaatc tgagcccatt
    18721 tttgaaaatg gagatcaatt aagggatcaa gtgattttag caattcactt acctaaaaat
    18781 agctttaact aataaacttt caattcgaga aaatgctttc aaatgctaaa tagatacatt
    18841 acaatagctt tagcaaacaa aaaggagaat atttttatgg gaatattagt ttttgatttt
    18901 ggtggatcgg ctgtcaaata tggttgttgg gatggcaaag agattaaagg taagggacaa
    18961 tttgcaacgc ctgaatcttg ggaagaaatg aaaacgcaat tatttcaagt ttataaaaaa
    19021 atactcgttt cttttgaagt cgaaggaatt ggaatcagct ctcctggagt agtgaataat
    19081 gagaaacagg tgattgaggg aatcagtgcg attccttata ttcatggatt taatattttc
    19141 cgagatttgg aaactctgtt tcaactccca gtaacgattg aaaatgacgc caactgtgcc
    19201 ggaatggctg aattttatga aggtgctgcc cgtgattatc aagatgttgc ttttgttgtg
    19261 gcaggaactg ggattggcgg ggcgttgttc acgaaaggac aaataaataa aggggcacat
    19321 ctttacggtg gagaatttgg gttgatgttc ttagatggcg ataagacatt cagtaaactt
    19381 ggtacagcgg tacagatggc ttggcgttat tgtgaacgca aaggtctcga taaaaatgct
    19441 tataccggaa aagatgtctt tgaattagca gaaactggag atgcaatagc aaaagaagaa
    19501 gttgagagtt tttatacgta tcttacaaag ggattattca gtattcaatt ttcgtttgat
    19561 ccagaagtga tcgtattagg cggcggggtt tctgcaaaag aagggctcat tgatgagatc
    19621 aaaagccgaa tgaagaagct gacagaacaa ttcgatctgc atgatttcga accgcagatt
    19681 ttattatgtg agtacagaaa cgatgctaat cttgtaggtg cagcagcaaa ctatctcgct
    19741 gtacgtcaag gagagaatta agagctttag agaaggtgca gcttgcataa aagaagagaa
    19801 tgaaatgaat aggagatttt tacctaagga atgttttatt tgctgcagta tgataaaata
    19861 tctgagaggt gaaaatgatg tcaaaaaaaa ataaagatat tgaagtgcgt atagaagaag
    19921 tgaaaaaaga tatcaaaggt aagaattatg aagtcactca gttatttata gggaaaaaaa
    19981 tgattggtga gatcttagcc tatgggccaa aagaatatga aattttcttt ggtgaagaag
    20041 attttggaaa agaaaaaagt cttgaaaatg cgatagaaac agtgattcga cactggaatc
    20101 tgcacgaata aaaaaatatc aaaaaaactt tcaataaagg gttgcaaaaa tctggaaaat
    20161 taggtattat aactaagtca ggttgataca aacctttcgg aggagtagcg aagtggctaa
    20221 acgcgacgga ctgtaaatcc gttccttagg gttcagtggt tcgaatccac tctcctccat
    20281 ttcattgggg tatagccaag cggtaaggca agggactttg actccctcat gcgttggttc
    20341 gaatccagct accccagtat ac
//
LOCUS       DAFEKH010000052        20074 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.054, whole genome shotgun sequence.
ACCESSION   DAFEKH010000052
VERSION     DAFEKH010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20074
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.054"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(266..1633)
                     /gene="nhaC"
                     /locus_tag="LP386_002163"
     CDS             complement(266..1633)
                     /gene="nhaC"
                     /locus_tag="LP386_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBL1919376.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(1742..3163)
                     /locus_tag="LP386_002164"
     CDS             complement(1742..3163)
                     /locus_tag="LP386_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1919377.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(3406..5283)
                     /gene="tdc"
                     /locus_tag="LP386_002165"
     CDS             complement(3406..5283)
                     /gene="tdc"
                     /locus_tag="LP386_002165"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBL1919378.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(5574..6830)
                     /locus_tag="LP386_002166"
     CDS             complement(5574..6830)
                     /locus_tag="LP386_002166"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HBL1919379.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(6942..7147)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            7410..8711
                     /locus_tag="LP386_002167"
     CDS             7410..8711
                     /locus_tag="LP386_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBL1919380.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(8780..9379)
                     /locus_tag="LP386_002168"
     CDS             complement(8780..9379)
                     /locus_tag="LP386_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL1919381.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            9633..10514
                     /locus_tag="LP386_002169"
     CDS             9633..10514
                     /locus_tag="LP386_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1919382.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            10527..12137
                     /locus_tag="LP386_002170"
     CDS             10527..12137
                     /locus_tag="LP386_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HBL1919383.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(12214..12873)
                     /locus_tag="LP386_002171"
     CDS             complement(12214..12873)
                     /locus_tag="LP386_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBL1919384.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(13156..13821)
                     /locus_tag="LP386_002172"
     CDS             complement(13156..13821)
                     /locus_tag="LP386_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HBL1919385.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(13968..14573)
                     /gene="dhaL"
                     /locus_tag="LP386_002173"
     CDS             complement(13968..14573)
                     /gene="dhaL"
                     /locus_tag="LP386_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HBL1919386.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(14601..15611)
                     /gene="dhaK"
                     /locus_tag="LP386_002174"
     CDS             complement(14601..15611)
                     /gene="dhaK"
                     /locus_tag="LP386_002174"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HBL1919387.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(15586..16032)
                     /gene="dhaM"
                     /locus_tag="LP386_002175"
     CDS             complement(15586..16032)
                     /gene="dhaM"
                     /locus_tag="LP386_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HBL1919388.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            complement(16071..17030)
                     /locus_tag="LP386_002176"
     CDS             complement(16071..17030)
                     /locus_tag="LP386_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL1919389.1"
                     /translation="MTYTHLTPTELVMIEAYFNQSHSVSKVAHLVQRSRQTIYNVYRF
                     LKSGGSAISYYEQYKKNKRNCGRRPIVLPDGQQEYIQKKVAQGWTPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDPHDLPMKGKRKPNGHKEKRGKQAFRRSIQDRTTDYIQFNHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPAGRQAIDIENRLNQWFQSVPKHLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNK
                     VSETFIQSVASKRNHIPRKSLHYRTPLEVFLSYVGKDDLSSLI"
     gene            17200..17520
                     /locus_tag="LP386_002177"
     CDS             17200..17520
                     /locus_tag="LP386_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HBL1919390.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(17632..18501)
                     /locus_tag="LP386_002178"
     CDS             complement(17632..18501)
                     /locus_tag="LP386_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBL1919391.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(18597..19901)
                     /locus_tag="LP386_002179"
     CDS             complement(18597..19901)
                     /locus_tag="LP386_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBL1919392.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEDTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(19898..20059)
                     /locus_tag="LP386_002180"
     CDS             complement(19898..20059)
                     /locus_tag="LP386_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919393.1"
                     /translation="MKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
BASE COUNT         5725 a         4147 c         3663 g         6539 t
ORIGIN      
        1 aatacgctga ccatttatcc tatggtcagc tttttatgta aaagaagata ctacttctaa
       61 cacattgttt atctgtaaaa aagagcgtgg gacaaaagta aagaacactt ttgtctcacg
      121 ctctaaacac gtataaacgg cggaagcaga agcaactcct tcggaaataa gctgaaattc
      181 acaaaaattt aaaaagcaat tttcttgagt ttcttcttat ttcttggagt taaacgcttc
      241 tgtcccagcc tcttttttcc ttccttcaat tttttacacg tcgacgattc aataaaaaac
      301 cgcctaatat tgtaaagaca ggtgcaagaa tcgagaaaaa ggcgaatggc aagtaatgca
      361 acgcgctaac tttcatcgtt cccataatga atgtgccgct gactccccac ggtacgagag
      421 aattgacggt cgcacctgaa tccgctagtg ttcgtgtcaa ataggttttt gataagccaa
      481 cgtcatcaaa agaacgcttg aatgtttctc ctggaagaat gatggacaga tactgttctc
      541 caacgatcag attgattccg atacagctca aggcagtaaa cccgactaaa cgagaaggtc
      601 ggtccatctt ttcttttaat tcttgaacga tggtatcaac gatcagatat ttgatcagta
      661 acccacctaa tgccaatgca agtaaaatca aactagcaga acctaacata ctcatgatcc
      721 cgcctcgaga aagcagttca tctagctttg gatcaggtgt atttgcgaca taaccattca
      781 tcaagatgtc tgctgctttt ccgaccgtca aacttttctc atggataaaa gaaagaacga
      841 gagcagctgt cgatcccgct agtaatgtag ggatagccgg aatttttttg attgcccccc
      901 caaataaaat aactagtgga atcaatgtcc aaggagagat ccaaaagctc gctttcatgt
      961 tttggatcat ttcattgata ctagctagat cggctgaatg actgttatgt cctaatatcg
     1021 tataaaaaat caacgaaagg acgaatgctg ggaaatccgt ataacgcata ccagcgatat
     1081 gttcgaatag attaactcct ccaatacccg ctgccaagtt ggtcgtatct gataaaggcg
     1141 agcagttatt ccctaaaaag gcaccggaaa cgactgcgcc tgtagtcatt gcatcattga
     1201 atccaagtaa atgaccgatc cccaaaaaag caattccaat cgtcgaaatc gttgtaaatg
     1261 aactgccgac agtcactccg acaattgcac aaacaagaaa tgctgtcggt aaaaagaaac
     1321 gcacagaaac aagtttaaat ccataaacca taatcgtagg gatggttcca gataaaatcc
     1381 atgaagcaac taagacacca atcaaaagaa aaatcaggat tggaatgatc cctggagtga
     1441 ttcctttgat gatcccgtca tggatctcat cccatgtgaa ctttttaaat ctgccataaa
     1501 acaacaaaca catgaaagct gcaaggatcg ggatatgtgg cgagagctgg aatccgatga
     1561 tcagtactcc taggagtgcc aacaacacga tcaatacagc gatactttct tttaaagaaa
     1621 tatttttatt catcgtcgat ctcctatttc aaatgaaaag gccctgccat gaaaaaacta
     1681 ttcacttggc aggacctcct actaaatcag cgacaaaacg tcggctgaaa gacttatttt
     1741 tttatttttc ttctaaactt ttttctacct caatccccca agaatctttc ttgaagtgat
     1801 tgatgatcaa tggaataacg aacatgacca ctgtgatagc tgctactaat aatgcatcac
     1861 tcaatgtcgc tgtacctaat gtagcaaata cgacaacgat gatagagaag atcagcatgc
     1921 agctgactac ccaagctaat ccgtttccgt ttttaccaat tcggtaagga cgttcgaatt
     1981 ctggatgttt cttacgcatt ttaagcaatg aaacagcaat caaaatgtac acgatacaat
     2041 aaataacagt tgtagcattt gtaagtgtca agaatacagc acttacgtca tccattacac
     2101 cataaagcaa agcaaataat gaaataacga ttgattgtgt tagaacgaca tttctagata
     2161 cgccgtattt gttttcttta tggaatccga attttggtgg aaggaatcct tcacgagcta
     2221 cttggatgat tgtttttgat ggtccagtaa cccaagctga taattgtaaa agcacaccaa
     2281 taaataccat gaagctgaag atatttccga tcacttctgg taagcctagg atttgacagt
     2341 caatcaagat aggctgcgtg atatttgcta attccatttt tccatctggt acgacatttg
     2401 ctacaagcat cgcattgatg acattcaata aaactaatcc gatcaaagcg ataaatacgc
     2461 cttttgtata attttttgtt gcgtctttca aacgaggcat gtaaacagaa ctcatttcga
     2521 tcccaacaaa aataaatgtg ataccagcta agtatttcaa tgaatcaata tgttccaagt
     2581 cagggaaagc ttttgaccat gaaaagtcac ctagatagcc gtttgagact agtccgactt
     2641 tgaaggctgc caaaacacct aaaacgaaca tgatgactac tgggatatat acccctagcc
     2701 atacaccgat gttcccgccg acttttgcca tatcgaattt caagttcaag atcgtgatga
     2761 tccagtagat aactaaaata caacctaaaa cgaaccagtg attattgcca agttctacat
     2821 taccaaatgt gtttcctaac aatggtccta aagtagaagc gaccattacc atacctggga
     2881 acatttgcac ccataatagc catgcaacga caaatcccca tttgctgccc agtgctgttt
     2941 ttacccataa ctgaggaccg ccttcttgag gaagcatcgt ggaaagctca ccggaaacca
     3001 ttgatatcgg accggcaaaa aacaaaactg caaaaattga ataaaaaatc aatgtccaac
     3061 cgactgcggc taacgtagga atactccgaa ccgttgcaca cagtgccatt gtcagaccga
     3121 taaaggtccc aagacccatt ttacttactt cagatttact caccgttgac actctccttg
     3181 attttttgga taaaataacg gtgtctttga agtagtttca gcaataaacg aaacaattca
     3241 gcgaatattt gaggggattc tttgagttta ttgcttgaag ggtttcttca aagacaacct
     3301 caaaacaaag ggatcgaaga gcttaggtct ccccttgctc ttcagatcca aacatgcgtc
     3361 agaaacagtt agtattcaag ctgttttcta acatgattac cttgcttatt ttgcttcgct
     3421 tgccaataat tggtctgcgt agattttttc caatttttct tgaagagctg ctttgatttt
     3481 ttcagcatat tcttcaaagt gttcttcttt gttcatgtat ggtgtcatta cgctggcacg
     3541 caatacagtt acttttccgg cacggttcca ttcttcatct gagaatccta gttggttcac
     3601 aaattgtaat gggctgttgc catagtctgg gatagcaaag tcagtatgtg aagttaagaa
     3661 ctcattaccg taaatgcttc ctttcacgta tgaagaataa tcatatacgt catggttcaa
     3721 tttattcatt gcaactaagt catcgttgcc tttttctttg aatacatagt ctaccatatt
     3781 gaaatctgga taagttaatg gatgaacttc gatttctttg tctcctactt taaatgacaa
     3841 gtcattcaag aagttgtaga aacgatgtgc accttcgatt gatgcaccca ttaatttacc
     3901 atatcctgtg acattcaaag gtaagacatg gtgtgctgcc caaacgctgg ctgctgttgc
     3961 ccctgctttt gaaccttcca agatataagc cccaagtaat gctgggatat ctgcgccttt
     4021 ttcaaataca tatgtcgcaa agtaagagat aacgtctctc atgcggatat ctttgatgac
     4081 gataccaccg gcagaatatg gaacatagcc cattttatgt gggtcaatcg ttacagattc
     4141 tgcttcttcg attgctttat atgcactgtg tacttcttct aagatataat ctttgttttc
     4201 tgtaaagaca ttgtatttgt aatgaacatc ttttaaatct tcaaatggaa tgaagttgtt
     4261 gtcttcgtct aagaaaatcg cacggccgta tccgccataa gcagcatcta cgtgtaagta
     4321 gaagtaaata ccgtcttttt ctaatacgcg acgcaatgca acgattttat cgataccgtc
     4381 gattgctcct tcttctgttg atcctacaac accgactaca cctaggattg gtgttttttc
     4441 agctgctaga ccacgaacga ttttttcaag ttcgttgatg tccatgcgat agttgtggtc
     4501 aactggcact ggaatcactt ggtctaaacc gataccgatg atgtcggcag cttttagcca
     4561 tgaatagtgt ttagtttgtg gaaccaacca ttttcctaat ttttctaaat gttttccgct
     4621 acgtgctgag tgagctttga tttcgtcgat tttttctggg acgctgtcta acagattcat
     4681 gatttcttct gttgacaagt tcattaattc ccaatcgctt tttccagcaa ctagttcagg
     4741 tgtcacttct ttcattgcaa gcggcaatga tttgatgttg cgggcatacc aaagtccttc
     4801 taagtttgct aaagaaccat cagcaacgat gtggccccag ccatctttat agctcattaa
     4861 ttttgcaaat tccattccta cttcttcttc catttggctt gttgcaggag aagattcata
     4921 ggcaacgtta ttaccattcc atagcatagc aaaattgtac gctagtaaag atggcatcaa
     4981 tgtttcagag ttcatatgac cccagtaacg tccggcatta tgccaaggaa cggaatgggt
     5041 acgcatccgc gctgaaattt ctgatagaac atcctttgtt ttattcacag tgtgttcaaa
     5101 actagcactg cttttttctt ctggcgtaat aataggcatg tcttgaggca tgtagttttg
     5161 acgccagcct aaatgttcat ccaccaattc attcaacaaa gctttataga tttggccgtt
     5221 ctcagctttg tccccaatga atagggcatt taggtttaga tctttcgaca atgattcact
     5281 catagtgaaa ccctcctaaa aaaatattta aattttgtcg agccctacat tacacctgtt
     5341 cttctattct gtaaactaag ttttggcctg atttttaatc atattttaat atgtatcaat
     5401 tatccgaatt gttcacactt ttgaaataat taaaaaaaac gagggaattt acaaatgtaa
     5461 actccctcgc aaagattgta ttaacgacaa ccagcgttct attttaggat gggtttcaaa
     5521 attggaatgt tgtaatagta tttccctttt tcaaggtaaa aacttactaa attctaatca
     5581 attactttgg ccaaaaagta atttttctta ccttttcgaa taaccacaaa cttaccatcg
     5641 aattcatcgg atggatttat gacaaaattt aaatcggtaa cgcggtcacc gttaatactt
     5701 atagctccgt ttgaaacatc ttcacgtgct tgacgtttag atggttcaat ttttgtggaa
     5761 acaagcagtt ccacgatatt ttcaggtgtg cttgaaattt caacgttcgg cattttaccg
     5821 aatccttgcg cgatttcttc cgcatttagt tctttaatat ttccagagaa caatgcttgc
     5881 gttatttttt gcgcttcttt caagtcttct tcactatgca caaatcttgt aacttcttct
     5941 gccaaacggc gttgtgcttc acgtttctca ggttctgtct ctactttttt cgctaagtct
     6001 tcgatttctt cttgagacaa gaaagtaaag aatttcaagt atttcactac atcgcgatca
     6061 tcttgattca accagaattg gtagaactca aatggtgaag ttttcttcgg atcaagccaa
     6121 acggcaccgc ctgcagtttt tccgaatttc gttccgtcag ccttcagcat caatgggatc
     6181 gttaaaccga acgcttctgc ttctggtcct tctaattttc ggattaggtc taatccagct
     6241 gtgatatttc cccattggtc tgctccaccg atttgcaatt gcacatcgta tgttttatgc
     6301 agatgcaaaa agtcgataga ttgcaggatt tggtaagtaa actctgtaaa tgagattcct
     6361 acttccaaac ggctggcaac gatatctttt gctaacatcg tgttgatgtt gaagttttta
     6421 ccgtagtctc tcaaaaattc aagtaaagag atttttgaca accagtcgta gttgttcaca
     6481 aatgtgatat ttgcatcttt accaaacaat tttctcattt gattggaaag tgcgtccacg
     6541 ttatgttgca cttgttccat cgtttgcaac acacgttctg ttttgcggcc gcttgggtcg
     6601 ccgatcgttc ctgttccgcc gccaatcaga atatatggat gatggcctgc caattggaat
     6661 cttttcatca tcataaatgg aatcaaatgt ccgatatgca tcgaatcacc agttggatca
     6721 acgccgcaat aaagtgaaat gctcttttct tcaacgagct cgcgaagtct ttcttcgttt
     6781 gtttgctgat taatggcgtc gcgccaagtt aattcatcaa taatattcat tttactgacc
     6841 tccgtgtagt ttttttatga aagcaggaac ctgctagcat gtgtaattaa ttatttcttc
     6901 aggataggat aggaaataaa aaaagtccct tggcatataa gccaagggac gaaatctcgc
     6961 ggtaccaccc aatttgtatg tctagatatc caacatacct ctcgaacatt taacgctgtc
     7021 gcgtggcaat cactgccaaa gactcctgaa atgtaattcg ctttaaagca tgtactggtt
     7081 tgcagcgacc accagctttc tgaaacattg gctttaacaa ctacttcgtt tcgatcttcg
     7141 tcttgttatt attaatatgt gtctatcata gagcgcaact ttttctttgt caacagaaaa
     7201 aggatatttt ttttaaattc ctcatttttt cttttttgaa tccgctctaa ttccgaacat
     7261 tttattttca attattgtta aaagaaataa ctttttctgt attttttctg caatttatcg
     7321 agaagtcact ttactttgcc tcttattctt tcttcgttac aataaggaat gggacaagta
     7381 aaaaaatgaa aaagcaaggg acgaggtata tggaaaaaaa gcaaaaaatt attttaggag
     7441 ccacttctgc tttaactatc gttattttaa ttctaagttt gttttttgtc atccgatcat
     7501 ctacaaaaaa agaaccaatc attcctgaaa aaaaaataac agaaaaagca aaagaaccga
     7561 cagatgataa gcaacaacta gttactcaag caaaaaatct ggctcaaagc tacgattatg
     7621 accaagcgat tgcgttattg gaaaaagata gtaagaacgg atctactgaa acacaacagc
     7681 ttcttcaaac actaaaaaag gagaaagaac aactgatcga ctggtctgat cctactcaga
     7741 tctctcatgt ctttttccac agcttgatcg tggacccgca aaaagccttc cactctcaac
     7801 aggcacaagg atacaaagat tatatggtga ctgttgaaga attcaaccgt tcgatcgaac
     7861 aactttatca aaatgatttt gttttagtta atttgaatga tttgatccaa aaagacgaac
     7921 aaggaaatct ttcctttaac gggcttgcgc tacctgaagg aaaaaaacca ttggttcttt
     7981 cacaagatga tgtcagctat tatgaatata tggataattc cggttttcct agccgattgg
     8041 tcgtatcaaa taacaatgaa atcaaaaatg tctataaaga gaaagataaa gaagaaatcg
     8101 gtgactttga catggttcct ctgatcgatg cctttgtcaa gaaacatcct gatttttctt
     8161 atcgaggcgc aaaaggtacc ttggccctga caggttacaa cggagtttta ggttatcgaa
     8221 catcaaaatc tcaatatgga gacaatgaaa aaacaaaaaa agagattaaa gaagctaaaa
     8281 aagtggcgga acagttgaag aaagacggct ggagctttgc ttcccataca tggggtcact
     8341 tgaatatgac tcaagcttca ctagaagatg taaaaaaaga caatgaattg tggcagcaag
     8401 aagttgcacc tatcctagga aaaacaaata ttctgattta tccatttggt gcagacatca
     8461 gcgactggca gccttattca gcagaaaatc aaaaatttgc ttacttgaag agtcaaggtt
     8521 tcgatatttt ctgtaatgtc gatgcttcta caccagcttg gggacaatta ggtacggatt
     8581 tctatcgaaa tgctcggatc aatatcgatg gcattcgttt tcaatctgat ttagacggaa
     8641 aaaatcctat tcttgatcca ttcatcaatg tccatgatgt ctatgacaaa gaagcacgcg
     8701 aatctgcttg attttacgtc atttatgaac caaaaaagcc gaactgacat tttatcgtca
     8761 gtttcggctt ttttatgctt tatttcttct tcggtgcgat tcccttgatc aggacttctg
     8821 tccattctgc tgtatatgga agcagttttg cgtatatctc cggcttagaa attccttcta
     8881 ccattgcttg aaaatagagg atcaagaact catccgaata tttcaaatcc acttttcctt
     8941 ctttccgccc tcgatggaaa agatcaagca tgatactgaa actttcttgc gtatacgcat
     9001 ccatcgcgtc agaaaattct tttttttctt tttttgtata gtatgtcatc aaatcgatat
     9061 aaaattgttt gttcactcga ttgagataac ggattttgtt ttcactcatg gcaatcagtg
     9121 tttcttcaaa tggaagattt tccgcaatca acgctttcgc ttcttgccct aaatcattca
     9181 taaatgcaaa aaatacttca taaatcagcc cttccttgct gccaaaatat ttaaaaatcg
     9241 tcgctttact tacctgagcg ttctcagcta ccttatccat tgtcactcca gcggttccta
     9301 tgtctgtgtt catcaagtca aaagctgctt gtaaaatctc tttctttttc tcttgtgctc
     9361 tcttttcaaa accgttcatt tgtagagcct cccgtaattt taaactttta taatatatat
     9421 agttcaaatt tattctgagg tttattataa ctatctattg agaaagtatc aagctagcaa
     9481 ttccttgttt atgaattcat tgacagaaat ttataaaaag aatattatgt actaaaataa
     9541 taaaaaaagt tttataaaaa ggtataaaac ctttttatta aactatttaa tcttgtttag
     9601 tatatatttt tagaaaaagg agtggggttt ttatggcaga aatcgtcaaa gtcacacatt
     9661 tgaaaaagag ctttggtcgt ttcgaagctt taaaagatgt ctctttcacc gtacattcag
     9721 gtgaagtcgt tggatttatc ggaccaaatg gttctggaaa atccacgacg attcggacac
     9781 ttttagggat tataaaaaaa gacggcggaa cggcaacgat ttttgggcaa gatgtatggg
     9841 aagatagttt atctatccat gaacgtcttt cttatgttcc aggcgatatc tctttgtggg
     9901 gaaatttgac tggaggagcg atcatcgatc tcttcatgaa gcttcatgga aaagggagtg
     9961 ctcaaaaaaa agatgaactg attcaacgtt tctctcttga tcctaagaaa aaagcaaaaa
    10021 actattcaaa aggaaatcgc caaaaagtgg gcttgattgc tgctttggct gttgattcgg
    10081 atctctattt atttgatgag cctacttctg gtttagatcc tttgatggaa acgattttcc
    10141 aagaagaagt tgaaaaattg aaagaacagg gcaaatccat cctactttct tctcatattc
    10201 tcagtgaagt cgagcgacta gcggataaag tcgtgatcat acgcgaagga acactcgatg
    10261 aagaaggaac actcgatgaa ttgcgtcatt tgactcgttc gaccatcact atagaaacag
    10321 aagcagagaa tagtcactta gcacaattga acggtgtcca tgactttgtg caaaaaggtc
    10381 acctcgctca atttgctgct gataacgaag ctttcgatgt gattttagct gaagcgtcca
    10441 aattaggtgt gaaaaaattt gaatctattc caccgactct tgaggattta ttcatgagac
    10501 attatgaagg atgaggagga agcgaaatga ctgataaatt ttcacgctgg tccacccttt
    10561 tttctcaaaa ccttagccgt gactggaaaa agatcctgat atggctagtc ggtgtcactg
    10621 ctttttctgg tggttttgtc cctgcgtttg aagaattgac ttccggacaa ggattagctg
    10681 gattatacga aaccttgcaa aacccggcaa tgattgcaat ggtcggacca actccagctt
    10741 cgaatgctgc tgagtatact ttaggagcga tgtatgcaaa tgaaatgttg cttttttgca
    10801 gtttgtttgc tgctgtgatc tctgttttac acgtggtgag ccaaacgaga aaaaaagaag
    10861 aacttggtct gattgaactt attcgttcct ttcgagtcgg acgtcaagca aactctttag
    10921 ctgtcatcgc tgaaagtatt ctgatcaatt tgcttttagc aatatcgatc agctgtacga
    10981 tgattttttt ccaagcggat tcgatcactg cagaaggtgc ttggcttttt gggctatctg
    11041 taggtagtat ggggattttg gggagtgccg ttgcactgtt tgctgcacaa ctgatgccaa
    11101 gttcagccag ttcgaatggt ctgtctttag cgtttttagg tggactttac cttctacgag
    11161 caataacaga tgtagctgat tcctcccttt cgatgtggaa tcctttaggc tggtcttatt
    11221 tgacctatcc atttacaact aacaactgga ttcctttgct ttatttgttt ttgttcagtc
    11281 taatcttgat aatcagttca tttgttttag aggaacatcg agatttgaac accggctata
    11341 tccccgaacg tgaaggaaaa ccgtatgcta aacgttctct tttatccttg cgtggtttat
    11401 tattctatct aaataaaggg atgacaatca gttggcttat cacttttggt ttgatggggg
    11461 cggcatacgg ctctatctac gggaatatgc aacagttttt agaaagtaac gacttaatga
    11521 aacagatgtt tatccaatct ggcgtctcaa ttgaaaaaaa ctttacaagc acgatcatgg
    11581 tcgtcttgat ttgtctagct gctattttac caattgctag catcaatcgt ttatttacag
    11641 aagaaaccca cggacgtatg aatcagctgt tcgcaacaaa aatttctagg aaccaacttt
    11701 attggaccaa tatgttacta gctattctat ttgctatatt ggcaatcctg attagttctg
    11761 gtgcactagg gctttctgct ttggcttcga tgaaggatgc gaaagacatg gatctattga
    11821 tgtttcttaa agccgggttc aatttcctgc ctgccgtttt agtgtttatc ggaattagtg
    11881 gctttctatt cggatggctt cctcgaatcg gtaaacttgc ttatatctac ttagcttact
    11941 cctttgcact caattacttt ggcggaattt tggatttacc agaatggttt tccaaaacag
    12001 ctgtccctag ctgggttcca cggatgccaa acgattcttt tgatctttcc gtgttcctta
    12061 cgttatcatg tatcagcctt gcactgttcg tccttggttc tattggttat aggcgaagag
    12121 acttactaga aggataataa aaaagcatgt acaatttcat gctagcctcc aaatctgggt
    12181 caaaaatcca acatttggag gtcatttttt tatttacaag tcttctaact gctctttatc
    12241 aatgatccag acttctcgat tctttctttt tacataacca ttctcctcta ataatttaaa
    12301 ttttctagat aaagtttcgg gggtcgtacc gataaatgca gcaagttctt tcattttcat
    12361 tggcaggaaa aagtgatcct tccctgtcgc tttagctaag tcaagcagat agacagcgac
    12421 tcgttcttct actttttcca tcatcaaaaa agttgtctgc tgctgtactt ttgttaattt
    12481 ctcaacgttg attgctaaaa gtttcagact aagggcggga taatgcagta agagttccga
    12541 gaaatctttt tgtctcaata tgcaaatttc cgttttttct agtgcttcgc caaataaaga
    12601 ctcatttgga acgcctagca actggctctc tccctcatat ccgcccggct ctattactcg
    12661 taaaagctgt tcctttccgc tagcagataa ttgatacact ttcatactgc cggaggccac
    12721 gatcactaat tgaggttctc cattcggcgc aagaatctgt tctccttttt ccacatagtg
    12781 atgtttgaca agtgcgtgta ctttttcttg atcttgctgt actaagtgat tgaacaaagg
    12841 aacaaatgaa acacataaat gatcatgact cataatctct cctccttcta aacagctatt
    12901 tctaataaag aaacataact tcccttattc caactgataa ttttctttta tcatagcata
    12961 aacgtcaagc gaaccagata ccagcaaata gagtggattt ctttttgtcc cttgctttat
    13021 tttccttctt ttgagacctt aagtaattga ttcctatcaa ttttttaaat atttactttt
    13081 tgaataatca aaaacaaacc ttcactcgca agccgagagt aaggtttgtt tttcgcattg
    13141 cttatttcgt gttgtctatt gaaatttttc cgcacctagc ttttgatata gtggtgctag
    13201 ttcttgtaag gtttcagcgg ttatttgctc aacgtgttcg atttcttgcg gatagaagaa
    13261 tagtttaccc atttgaaagg ttcggtctct catcgctttt ttcaactctt cttgtttctt
    13321 tgtatcggac aaatagtcag acaaagctaa gtggtcgtca agttcatgtt ctggttgcgg
    13381 ccatatgtaa taatccttga tatcgactgt tttgctccac tctttcagta tcgcaagcaa
    13441 ctggttatac gctgcaatgc taccatatcg ttcttcgctt ttataatgtt ggtacatcaa
    13501 atagatttgg tattgttttt gattcaacaa aactgctaga caggcattct cgtcttgacg
    13561 agattcgctt cggtacgcgc tccaaaaatg actgcgtaaa ttccagccat tcgtccagct
    13621 ttcgatttta ggtttgctca tgccgtacat atcaggcaaa agtgcagctg tctggagctg
    13681 aatctctttc catttttgcc agtgttcttt atattctttc ttgatttgtt caatcttatc
    13741 tgttggatgg ctctctttga gctgtttgaa tgcgtagatt ggtcgatcaa acaactgata
    13801 atctgatttt ccaagttcca ttgtttcgcc tctttccgtt atcttttgta ttctacctga
    13861 attttgcgat atggacaaat agaggttgtg aaaaagctgt tctgcatcaa gtcataagaa
    13921 cagccaaaca aaaaactgcg atgagcatca ccgcagtttt attgaactta aggttgattg
    13981 atcacatcta aaagcgttga aaataaaatg gcactagaag cagctcctgg gtcgatatgt
    14041 ccgattgcac gctctcctag ataggaagct cgtccttttt tagctaccaa gactttggtg
    14101 tgttcttttg cctggtcaat gatttctttt gttaaattcc ctgccttcaa tgcctctgtg
    14161 actggcagcc aaacatctaa catcgtttta tcgtcagctt ctgcctttcc tcggctttga
    14221 atacccgctg ttccctgctc gatcacttcg cctaattttt cttgagaatc aatagaatcg
    14281 acctcttttg tcgctttcat catgttcatg aatgcagatc cgtataacgg accagaagcc
    14341 ccaccgactt tcgatatcat cgccatagag aatactttga atgtatcgct gattgtttca
    14401 ggatgatcgg cttgaaaagc ttcttcataa gctgaaaccc ctcttcccat gttatttcca
    14461 tggtctccat cgccaatcgg ggtatctaga tcactgagat attgtttgtt ctgattgatt
    14521 gcctctgcaa attgcgtgag ccattcttgg atttcttgaa cggttagttt catattatca
    14581 cccttttatc ttgagatttt ttaccatgaa atcgtctgta cattgctttc taaagaatct
    14641 ttccattgtg tctccgtcaa gtcgatcagt gttagagaaa gaccttgcat atctagtgag
    14701 gtcataaaat taccgacttt tcggaaaact acattgacgc ctctttcttc caacagagct
    14761 aaaacatcat tcatgaacac gaactgttcc atcaaaggcg tcccgcccat tccgttgact
    14821 agtacacctg cttcttttgg taaattcgag taatcatcta aaatcttagt aacaagttcc
    14881 tttgccagta ctttagaagg ctgcatcttt tctcgacgat agcctggctc accgtggata
    14941 ccaacaccat actcgatctc atcttctcct agttcgaatc ctggtttccc tacttctggt
    15001 acagttgctg ctcgaagcgc tagaccgatc gtcttagttg cctgtacgac cttttctccc
    15061 agttctttca actcagctag ggaagcaccg tttcttgctg catcgcccac gattttgtgt
    15121 acaaggacag tacctgcaac tccgcgtttt ccagcagtat acgtactatt ttcaacggcg
    15181 atatcatcat ctacgatcac actttctact tcaatatcgt ccatagcagc taattccttt
    15241 gccatatcga agttcaatgc atcccctgta taattcttaa cgatcagcaa aactcctttt
    15301 ccactatcgg cttccttaat agccgtctga atctgatctg gagttggaga agtaaacaca
    15361 tcaccaagca ccgctgcact taacatccct tcccctacaa acccggcatg ggatggttca
    15421 tgtccgcttc ctccaccaga aaccaaacca acttgttccg ctttctgatt cttggctaca
    15481 acacgggaag attctacacg atgaacaagt tctggatagc tttttactaa tccttccagc
    15541 atttcttcga caatattgct tggatcattc atgatttttt tcaatttatt cccatccttt
    15601 ctttccggca ttttgtgctt ctgttaagat ttgctgagta tcatctgtta taccggcagt
    15661 gatggctgct gcaaaagctc cttccactaa aggcgcatcc accagatgat aacgttgctg
    15721 ctgctcttct tccaacatgt cttttgccag ttccgagttc aataccgcgc taccgatatc
    15781 cgcaaaaaca aaataactag ctgcatcgct tgattcattg actgcttcta cgattttcat
    15841 cgggtctgat ccgatctcgc catttattcc gccgagagaa aaaatttgca cctcttcgga
    15901 tttttgcatc tgctcaatca tttctttaat accatctgtt actttttgac tatgagaaat
    15961 aagcaaaata ctttttttca caagaatctt cctttctttt acatagttgc taacgattgg
    16021 tttcgctttc attaatgaac aattcaagta tataataaat ttttcgtttg tcaaattaag
    16081 ctagacaaat catctttacc tacgtaactc aaaaatactt ccaatggtgt gcgatagtgt
    16141 aatgattttc taggaatatg atttcgtttt gatgccaccg attggataaa ggtttcggat
    16201 accttattaa aatccatagc tttatataag ccatctttac gtaataagcc attcgaatgt
    16261 tcatttagtc ctcgttgaga aggtgttcct ggatcagcga aataaatcga aatatcattg
    16321 gtattactaa tctttttcca attcgagaac tcttttccac aatcaaatgt gatggattta
    16381 aacaagtgtt tcggtacaga ttgaaaccat tgattcagtc tattctcaat atctatagct
    16441 tgcctaccag cgggtttcaa ggtgatgatc actttagata atcgctcaac taacgtgatc
    16501 accgcacttt tatgttttcc accgacaatg gtgtcacctt ctaggtgacc aaactcatga
    16561 ttgaactgta tataatcagt tgttctatcc tgaatcgaac ggcgaaaagc ttgttttcct
    16621 cttttttctt tatgtccgtt tggttttctt ttccctttca ttggtaaatc gtgagggtca
    16681 aaggttttat ctttaaacat ccgatatagt gtacgtaccg aacaagcaat aggaaactct
    16741 gctcgaccaa taaggacatc tggagtccac ccttgagcca cctttttttg aatgtattct
    16801 tgttgcccat ctggtaacac aatcggacgt cttccgcagt tacgtttgtt tttcttatat
    16861 tgttcatagt agcttattgc gcttccacca gatttaagaa aacgatagac attataaatg
    16921 gtttgtcgag aacgttgtac cagatgggct acttttgaaa cagagtgtga ttgattgaaa
    16981 taagcttcta tcattacgag ttcagttggt gtaagatggg tataggtcat ttgtactcac
    17041 tccttataat tctttcgacg gaactatttt gagtgtagca caaatgactt ttttagttgt
    17101 ctagcttaat tttacaatcg gcgatttcta attttgggaa aatatgtgta gtgcttcttg
    17161 aagtttgtta tactttaatt aaaagagagg agtgatcgaa tgattacaac aacaacgaac
    17221 agtgtagagg gaaaagccgt agtagcttat aaagggatcg tttttggtga ggtcattact
    17281 gggatccatg catttaaaga cttggaggcg gggttgcgaa atatctttgg cggccgctca
    17341 aaaagctatg aaaacgaact aatgggtgca agagaagaag cacttgccga aatggccgaa
    17401 cgtgcaaaag cattaggagc tgatgcgatc attggcgtaa aaatggacta tgaagtatta
    17461 ggcagcgaca atggcatgct gatggtcaca tgtagtggaa cagctgtctc cacgagataa
    17521 gtaggggaca tctgttttaa taactaaaga gagatgggac atgtagtggc actcaagaat
    17581 tagatttttc agtctaactt cgaggtactc taccttccca tcctctcttt tttatttctt
    17641 tttgcggatg attccgtaag ctgctgcgac taacacaccc gcccctgcta aggaataact
    17701 gacagaagct gttttttcat ttgtttttgg caaagtctga cttgttgatt tggatggctc
    17761 tgtcgtttgc tgaactgttt ctgtcgtgct tccagaggtc actgattttt ctcctgccga
    17821 atgcaaaata tcttttattc gttggaaact agctgctaag tcagcttttt ttgcttcaaa
    17881 atcattagca actgtttgtg cttcgctgat ctttccgtgg attgcttgac tggccgctgt
    17941 gatatccgct tgagtttgac ttagctttcc agaagctgtt tgagcaacct gatttaattg
    18001 ctgattgaat tcttttgctt gttggatctt cccgtcaaga tctgtttgga cagcttccgc
    18061 ttttgctttc gcttcggcaa gctttttctc aagttgtgca cggtcatttc ccactttatt
    18121 tttaagatca gctaaatctt gatcgattgc tgcttggtct tctttcaatt tgttttttgc
    18181 agcttctaat gcttcttcga gttcttttct tttattttcc aagtcttgca aatgatcgat
    18241 ttggtcagaa gaggtagaac tatttattga tgtatcttct gaagatgaaa tcgtttctcc
    18301 tgaattatct gtcggtacat tggaagtcat ttctgtttcc gaggcaccgt tttcagcacc
    18361 agaagagctt atggttgttg aaggttctgt ttgagcaggt tcagaagttt ccgcaaaagc
    18421 tgtctgtccc aataagaaaa tactggaaac agcaattggc cagattaacg gcttcattct
    18481 ttttttcatc acttttccca tccttactac tttttaacta atttcttatt ataagcaaaa
    18541 atgtttggaa gaaccataaa cacaacaggc tgtttgtcta aaaaacggtg catcttttat
    18601 ttttttgtac gttccgggct tttccatgtc ccgcttccat aacctaaaat cgttttgact
    18661 gctggaatga aagtcgtcac gatcgttatc gcgttcacta tccagaacaa aagcatatat
    18721 agtggtgcga aaagaaggta tttcaatttt cttcgtcgat catctacaat cagcgaagct
    18781 agcaactgga aaaatcctgc gaccatttca aagcagatga acacaaaact gaatgtaaaa
    18841 gtaatataaa tctgttcgta gtttccttga tatacataat gcccgattaa tccagcaaaa
    18901 agaactacgg aaatacaaaa gaatattgac cagacaatac tcaatgtttg atcaatgaag
    18961 atgatcgttc ttccaatatg tttaaaagga tggagcatca cttttttgaa attcgtcagc
    19021 cagacttctg ttccaccttt tgcccaacgt tttctgtgtc gatatagcat cttcaacgtc
    19081 acaggtactt ccatgaaaaa gataatctca ggagcaaaaa cagataacca gtcatttaac
    19141 tgatgatccc aagcaatact gatgtcttct gtcgctcgat cttgtctgaa tccgcccaca
    19201 tcgatcaagg cttcttttcg atacatcgta tttgctccac tgtacgcata aagaccaccg
    19261 aaaacagctg actgtgttcg tttaatgatg cccacgatac ttgagaattc aaccgtttga
    19321 gattttgcaa tcaatttggt acgattttgg acatccatat ttgcagtgac cgcagcaata
    19381 tgtcttgcac cagggcgaat gaaataattc acatacctaa tcagtgcatc tggctccggt
    19441 accgtgtctg catcattgct taaaatcaat ttcccttttg caaaggcaag tccgatatta
    19501 aacgcgtggg cttttccttt atttttttcg atccgaacca cacgaagatt agcgtatttt
    19561 ttcatcagtc tagctaatat ttctggtgtt tggtccgttg aaccatcgtc tgtcactaat
    19621 acctcatagt tgtgataatt caatttcgtc atcaaatact cgattgtatc ttcgatcaca
    19681 atttcttcat tatgggctgg caccatgatc gtgatgaacg gttcgacact caagggaaca
    19741 tctacccatt ctttttgctt atgtttgtat aaaaacacat aacaccagac accaataaac
    19801 catacaaatc cgcctaaaat cggataagaa acgagaaaaa aatacataat agacaaacaa
    19861 gtatctaaga ataaattacc tgtatgggtg attgagatca tttcagttcc accccatttt
    19921 ctttatacaa atctgcaatg aatgtcgtat ctagattttt ctcttcggag acagaataaa
    19981 aacggaccgt ttctctctct tcttttgttc caaaacgttc cgtatacact tcttcaagta
    20041 attcttgtct ttttttcaat ttttcatctt cata
//
LOCUS       DAFEKH010000053        18929 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.055, whole genome shotgun sequence.
ACCESSION   DAFEKH010000053
VERSION     DAFEKH010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18929
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.055"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..1235)
                     /locus_tag="LP386_002181"
     CDS             complement(<1..1235)
                     /locus_tag="LP386_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBL1919394.1"
                     /translation="MSNDIQPEIRFPGFTEAWEQRKFECLLDKKDGVRRGPFGSALKK
                     EFFVSNSNFVVYEQQNAIYDNYETRYKITEKKYNELIKFKLEPGDFIMSGAGTIGRIS
                     RVPKQIKPGVFNQALIRLRINKEITDSEYFIQFIRADFMQRKLTGANPGSAITNLVPM
                     SEVKKWIVQFPILEEQKKIGNFFKQLDDTIALQQRKLDLLKETKKGFLQKMFPKNGAK
                     VPEIRFPGFTEDWEQRKFKEFSKKTGKKNTKDLDFPAYSVSNKAGLISQTEQFDGSRL
                     DDLEKTNYKFVEPNEFAYNPARVNVGSIAFNNLGMTVIVSSLYVVVKMSEDLDNEFIL
                     QFIKSPTFIKEVKRNTEGSVREYLFYENFANIKFPFTRNKEEQQKIGAFFKQLDDTIA
                     LHQRKLDLLKETKKGFLQK"
     gene            complement(1228..2820)
                     /locus_tag="LP386_002182"
     CDS             complement(1228..2820)
                     /locus_tag="LP386_002182"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HBL1919395.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLANFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHE"
     gene            complement(3330..4055)
                     /locus_tag="LP386_002183"
     CDS             complement(3330..4055)
                     /locus_tag="LP386_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919396.1"
                     /translation="MKKKKLLWICLAILLIIGGIEIFTTYRLKTNQPKQYVSDMLNII
                     EEIDSEMKAFSKTSMDLGERYDFKGFMEDKMDEVSSREIPEGTPKAVRDTKDTLLEAI
                     DNVNTALLTNDVKLLEQGQLCFSIAQAIYTEFLDGNIKEKSLNEKLNSFVETYTAIPP
                     TWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNAVTEKVGKDIPLRLLENGKK
                     DYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(4209..4535)
                     /locus_tag="LP386_002184"
     CDS             complement(4209..4535)
                     /locus_tag="LP386_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919397.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSRMTGSSGLEKSSVPLVTQ
                     ILQEQYNLNRTCDDVTITHDNGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            complement(4572..4937)
                     /locus_tag="LP386_002185"
     CDS             complement(4572..4937)
                     /locus_tag="LP386_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBL1919398.1"
                     /translation="MYCRKCGKEITNESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEQMGTILM
                     IAGVAGAIFGVLLGMSMSY"
     gene            complement(4974..5189)
                     /locus_tag="LP386_002186"
     CDS             complement(4974..5189)
                     /locus_tag="LP386_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1919399.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            5318..5653
                     /locus_tag="LP386_002187"
     CDS             5318..5653
                     /locus_tag="LP386_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1919400.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAKKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVDIDYEEEFLALYRSLSTEDAIRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(5729..7726)
                     /locus_tag="LP386_002188"
     CDS             complement(5729..7726)
                     /locus_tag="LP386_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919401.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFKHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVRDNSVKNALIENRGYFVKQGFTLERASKDIKKLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPIYQFTSVTRDDGRRVRNRRDPIILN"
     gene            complement(7824..8099)
                     /locus_tag="LP386_002189"
     CDS             complement(7824..8099)
                     /locus_tag="LP386_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1919402.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            8331..9065
                     /locus_tag="LP386_002190"
     CDS             8331..9065
                     /locus_tag="LP386_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1919403.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            9104..10246
                     /locus_tag="LP386_002191"
     CDS             9104..10246
                     /locus_tag="LP386_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL1919404.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(10874..11359)
                     /locus_tag="LP386_002192"
     CDS             complement(10874..11359)
                     /locus_tag="LP386_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HBL1919405.1"
                     /translation="MVRRVFFSFHYADVTRAMVVRNSWTLRGTKEAGFVDKAEFEKVK
                     RNGDIAIKNWIDNQLIGTSVTVVLIGKETLDREYVKYEIQESYKRGNAILAVNIGKIK
                     DFNQMTTTSQSVIKIIGQKPDGEYLWFDEIIDGQYDYISDDGYNNLGTWIDSAAYKKG
                     K"
     gene            complement(11361..12797)
                     /locus_tag="LP386_002193"
     CDS             complement(11361..12797)
                     /locus_tag="LP386_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HBL1919406.1"
                     /translation="MDKKVLIKRFSEAIEKGNAAIFAGAGLSMSQGYVSWPELLNDPA
                     TEIGLDSKKETDLVTLAQYYKNENGGSRGILNQILMDNFGEELEISENHRILASLPIE
                     TYWTTNYDHLIEKSIREAYKNPQVKKNYTQLATTNPNVDTIVYKMHGDIDDVSSTVIT
                     RDDYEKYDDDSYALFKETLKGDLLTKTFLFLGFSFTDPNLERILSDIRWVLRENQRPH
                     YCIMRKILKENFVDSEDFFDQERYNYELTKRRLQINDLSRFSINVVEVDDYSEITDIL
                     KSIRKKYLRKTIFISGSAVDYTPFTSESKGLKFVEKLAYRLSESGYRIVSGYGLGIGN
                     SIVSGVLKQRRNLRKNNIQDVLSLRPLPLDMPHEWRRYRENIIAESGISIFVFGNKLE
                     SGEIVTADGMIEEFELSVQNENIVVPIGFTKGASKVLFDKIQENFSDYFDDSLKSKFQ
                     ALEKLDTEGEVDKKVEQIVSLINSIQED"
     gene            complement(12830..13681)
                     /locus_tag="LP386_002194"
     CDS             complement(12830..13681)
                     /locus_tag="LP386_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HBL1919407.1"
                     /translation="MYKAYELDFTNADLNAFSSSSQSYTHVVNQIDHNQKSINKRIEN
                     LFESENDLVDYYSKDSKILDADEIIKDWFPTIKADIFISHSHADEKLAIRFASWLFEN
                     FGLTAFIDSSVWGYSSDLLKKIDQKYCYKEQTKTYDYDKRNVTTSHVHMMLSTALNNM
                     IDSTECLFFLNTPNSISLSNEITNEQKFTYSPWLYSELTTASIVEKKNPRLESNPQMS
                     TEDVRSIIKHYSSQENLQIKYSLNLSELTYLRKADLKKWALDAVECTKGSNTLDILYK
                     NTIFTNL"
     gene            complement(13837..14082)
                     /locus_tag="LP386_002195"
     CDS             complement(13837..14082)
                     /locus_tag="LP386_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1919408.1"
                     /translation="MLFLKEEKIIDKENVIGSNIRRVRLEKGIGQTELIRDLQLRKIA
                     ITRETLVKIEGGRQHIKLDQLKAIKDILQVSYEDLLQ"
     gene            14187..14960
                     /locus_tag="LP386_002196"
     CDS             14187..14960
                     /locus_tag="LP386_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919409.1"
                     /translation="MKKFAIILTCALLIGTISGCTTSDTSSTSTETSTTTSEKNYPIH
                     FFPVPDGFEAYYHDKKLNVPLSETESTEKILPIEIERNQDDIKLKADLPLLNSTQIDR
                     HENIKVNIEKGALAQLYTEKVEQFFEAGANKDFSKISDYSDNFFNETQDEITNSTFMA
                     EDMYNMKLKKIKSYDYPLNLTLNKGILSFVLAGYVDYEYTADYLETPLQHDNNDINFR
                     FIYNSKSKTWLVDQLSTINTGFHELPKPDNETALVIKTF"
     gene            complement(15013..15327)
                     /locus_tag="LP386_002197"
     CDS             complement(15013..15327)
                     /locus_tag="LP386_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919410.1"
                     /translation="MADENKVVPLETLVINKEEFEQLFLDFFVQYDRIYDFSSSLDLF
                     ELEAEIIENSREENGKIIISVEKFNELFSETFEIDTDYYQPQEVFQSFRNQIIRSGKT
                     VN"
     gene            complement(16846..17064)
                     /locus_tag="LP386_002198"
     CDS             complement(16846..17064)
                     /locus_tag="LP386_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919411.1"
                     /translation="MKLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKHEIKNNLKYCYLEKSEEIIHELNGF"
     gene            complement(17079..>18929)
                     /locus_tag="LP386_002199"
     CDS             complement(17079..>18929)
                     /locus_tag="LP386_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919412.1"
                     /translation="LVENSNNEFVATKFSDNFLSTFSDSLKSGYYRYQANLWGISIGL
                     TALAIAYVFSAFVIITAILELAFKRVLGVLVFATDIETGQRSKVVLSDILQCYLTVGF
                     QGFGLSMFAMFINFLNAGQGISTNIFIKTIAYICAVFVLIKGSGTVMRYFGVDIGLKE
                     GYGQLASAFGMGAMLFRKGSTGFNRAKGSGNGNGSDSGEGEDRKPEKNFGETLSKKAG
                     KTGRALGYAHERGLSGLASDGATMASERAIKPFKSMRDMANDTKNKFKEGLDDGTVSA
                     INKNSKPMLAKNKEDETGKYADSMPTRLSDRKDGAKVENADRIMSSSERMREAMKNNA
                     ESNNNPVSAIQQKVQQDIEERKNAMHGQAKSAEELINQKRQEAKYTPEAMNREEMLRK
                     RVEGRTGANTDEKEALTKERIQEAKNSNTGLEKLVKENLQNSTSSQGGRSVDVRENIQ
                     GSLNGHVGRNVDVRENLQSSSNGQGTKTIDVRENVQNSTSSQGFKSMDVRENVQNSTS
                     SQGFKSMDVRENVQSSTSSQGFKTVDVRENVQKDSGEMKEKTQKINIVEDRKSAKKFD
                     SNHETVIIDSEIRENDKGSKPRRRFTYEDNELFRDTLNDPNPLFDNLLKK"
BASE COUNT         5948 a         3527 c         2628 g         6826 t
ORIGIN      
        1 atcttttgta agaagccttt tttcgtttcc ttcagcaaat ctaacttacg ttgatgaaga
       61 gcgatcgtgt cgtcgagttg tttgaagaaa gcgccgattt tttgttgttc ctctttattc
      121 ctagtaaaag gaaacttgat attagcgaaa ttctcataga ataagtattc tcgtacgctt
      181 ccttcagtgt tgcgcttgac ctctttgata aatgttggtg acttgataaa ctgaagtatg
      241 aactcattat ctaagtcctc gctcattttc acaactacat aaagagagct aacaatgacc
      301 gtcataccaa gattgttaaa tgcaattgat cctacgttta ctcttgctgg attataggcg
      361 aattcatttg gttcaacgaa tttataattt gttttttcta aatcatccaa cctactacca
      421 tcaaactgtt ctgtttgaga aattaaacct gctttattac ttaccgaata ggcagggaag
      481 tctaaatctt tcgtgttctt ttttccagtc ttcttactaa actctttgaa cttacgctgt
      541 tcccaatctt ccgtaaatcc aggaaaccga atttctggca cttttgctcc gtttttaggg
      601 aacatttttt gtaagaatcc ttttttcgtt tcctttaata aatctagctt acgttgttga
      661 agagcgatag tgtcgtccag ttgtttgaag aagttcccaa ttttcttttg ttcttctaat
      721 attggaaatt gtactatcca ttttttcact tctgacattg gtacgagatt tgtaattgct
      781 gaacctggat tagctcctgt gagttttctt tgcataaaat ctgcacgaat aaattgaata
      841 aaatattctg aatctgtgat ttctttattt attctaagtc taatcaaagc ctgattgaat
      901 acacccggtt ttatttgctt tggtactctt gaaattctcc caattgttcc agcgccactc
      961 atgataaaat cgcctggttc taatttaaat ttgattaatt cattatattt tttttcagta
     1021 attttatatc ttgtttcgta attatcataa atagcatttt gttgttcata gacaacaaaa
     1081 ttgctattag atacaaagaa ttctttcttt aaggcactcc caaatggtcc cctccttact
     1141 ccatcttttt tatcaagtaa gcattcaaac ttacgctgtt cccaagcttc cgtaaatcct
     1201 gggaaacgaa tttctggttg tatatcatta ctcatgtttg aacacctcca gcgcaccttg
     1261 taaccacgct tcattttcag gtgttgtttg cagggaagag atagcttcta aaagttcttt
     1321 ttctagcact tgctgttctt gtcgtatctt cttgatgtca tttccgacat gaaccatatc
     1381 aattggttct tcttcttcaa acgtatctac atagcgtgga atatttaagt tatagtcatt
     1441 ttctttgatt tcatcaaagt ttgccaaatg agcgtatttc tcgacatctt ttctttcagc
     1501 ataggtttcg aggatttttt gaatgttttc ttccgataat ttattctgat tttttccttt
     1561 gacaaattct cgactagcgt caatgaataa tacgtctcga gtttggcggt tctttttcaa
     1621 tacaatcacc gtcgttggaa tcgatgtccc gaagaacaag ttcgcaggca taccgatcac
     1681 agcataaata ctgccgtctt ctagtaattt ttgacgaatg accccttctg cagcgccacg
     1741 gaataaaact ccgtgtggca agacgatggc catagtccct gtttccttca aatgatagaa
     1801 accatgaaga agaaacgcaa aatctgcttt ggattttggc gctaattttc cataacgatt
     1861 aaaccgagaa tcgtctaaga aggtcgtatc tgctgaccaa ttagccgaat aaggtgggtt
     1921 cattactact gcatcaaatg tgtaaggttc atctgttggc caatccttat tcaacgtatc
     1981 cccattgcgg agattcattt cttcggcatc taccccatgt aaaatcaagt tcatttttgc
     2041 tagattgtat gtcgttgtat ttaattcttg cccatgatat ttaacgttat ctgggtgagt
     2101 taagtagtta cgcacattta acatcaatga acctgaaccc atggttggat caaaaacact
     2161 aaagaatcgt cgttcttttt gatccaacgt cacgatttgt gccatcatat cagaaaccat
     2221 atgaggcgtg taaaattctc cggctttctt ccctgcttct gaagcaaatt gactgatcag
     2281 aaattcataa gcatccccga tcacgtcccc atcgtgacct aaaacttcca cgtcattcaa
     2341 tttcttaatg acttcggtaa tcgtcacatt tcgttgttgc tcatctgttc ctagtttttt
     2401 tgattggaga tccacatcat caaataaccc attaaattga ttgtaggtag atgccaattg
     2461 cacaaaggct ttgtttagat cattcaattg gaacgttgct tgttttgctt gatccgctaa
     2521 gacgttgaaa agatactctg gcgaaatcgc ataccccaaa atatcaacga ttgttgcaat
     2581 cagatcttct tttgattctt catctgaaag taattcgcga tacaacatcg tttgtttgct
     2641 taccgtatca tattcctcta aggattcatc tgctaaaaga accacttgtt ccaacaaacg
     2701 gtcggataaa tatttataga aaatcagtcc caataaataa tttttatatt ctgacgcatc
     2761 cattttgcta cggagattat ctgccgcact aaataatttt tgatttaatt ctgcacccaa
     2821 aaagatacac tcctatctct tatttaaagt tgctatatac cctcttattt tagcatactc
     2881 ccttttagaa aaagcaaaaa aaaaaagaaa gaaacttatt cttgctaata aactacgcga
     2941 aaggagtcta acgttgtttg atataactta gactgatcgt taacttattt tttatatttc
     3001 tacatagtta tctttagaac catttcagat acatatgaaa caattacata tgattttttc
     3061 ataaaaaaac agtactgtct agtagtataa aatatacaaa tttcttaaaa attttttcac
     3121 taaaatcact acctgaaaca gtctaaaaca cttatatatc aacgtttaat gaaactatct
     3181 ccgtttcatt tcagatacaa ataaatatag tcgggctcca aatccgaaaa aaaatacccc
     3241 cagtagctta tcctaagcta ctggagatgt ataagtacgg tcatataaca acggggtagg
     3301 gtaaataaat gaaaaagatg gaagaatcat tattcaataa cttttttaaa tacttcgttg
     3361 taatcagtta cctgtccgtt cttaaatacc acagaataat cttttttccc attttcaagt
     3421 aaccgaagtg gaatatcttt accaactttc tctgtcactg cattactgat acctgttaga
     3481 ttagctaata aatctgataa agattgagca tctgtagaaa tctctgtatc agtatttatc
     3541 gtgattcctt tatcttcatt tacaagtttc caagtaggtg gtatagctgt gtatgtttct
     3601 acaaatgaat taagtttttc attaagtgac ttctctttta tatttccatc taaaaactct
     3661 gtatatatgg cttgagctat actaaaacaa agctggcctt gttctaataa ttttacatca
     3721 ttagttagta aagctgtgtt cacgttatca atcgcttcaa gaagagtatc tttggtgtcc
     3781 ctaacagctt taggtgtgcc ttctggaatt tccctacttg atacctcgtc cattttatct
     3841 tccataaacc ccttaaaatc atatctttct cccaaatcca tagaagtttt tgagaaagct
     3901 ttcatttctg agtctatttc ttcaataata tttaacatgt ctgatacata ttgtttaggc
     3961 tgattcgttt ttaatctata tgtggtaaat atctcaattc ctccaattat caataaaatt
     4021 gccaaacaaa tccataataa ttttttcttt ttcatttttc ctcctataca ctgctgttat
     4081 aacagtgact aatgtaaaga ttttcccagc aatcatcaga ctattattta cagggaatca
     4141 aaaaaactcc ttagtaagct tacaccttta ggagttcctg tttgaacggt atgcataata
     4201 catttaaatc aatttaacat taacacctca gtatatggta tctctacata tacacggtct
     4261 ttttttggat agtactcgac atttatattg atagcacttc cattgtctaa cgtagcttta
     4321 gcccggtacg tgttatcacc attatcatga gtgatcgtca catcatcaca tgtccgattt
     4381 aagttatact gttcttgtaa aatctgagtt accaatggta cagatgactt ctctagtcca
     4441 gatgaacccg tcattcttga aaaaattata cctataatag ccaatacaac gatacctata
     4501 atgacaaact tcttattcat atttacttta ttcaactttt tatctcctat ctccaaaatg
     4561 attttctctc atcagtaact cattgacatc cccaatagta caccaaagat ggctccagct
     4621 acccctgcta tcatcaaaat cgtacccatt tgttcatctt tctctcgata taagtaaccc
     4681 ataataacag caacagcacc aaataccaca ggaataaatg ctaatgatac taccatagaa
     4741 atccaaccaa taatcaaata cagcttccct gtctcttgtc catgtacgat ttgttccttc
     4801 atttcattaa ttgtctgctc agtacttttc tttactgtgt ctgttccggt tgtctcatct
     4861 gtttcttgta atgctccgca aaactggcaa tacttacttt catttgttat ttctttacca
     4921 cattttctac aatacatgtc ttctcctcct aaaatcattc aattgcttat tagctaactg
     4981 tttactttat taaatacatc agaaaacagc tcatttattg gtacacttaa tatctcagaa
     5041 agcattttca tttgataggg tttaggaatc gttctccctg tttgccacga acttacacat
     5101 tgctgtgtaa cattcatttt tttggctaac tcagtttggg aaagtccttt ttcttttctg
     5161 tatcggctga gattacttac ttttttcatg attctcccct cctgttttat tatatacaac
     5221 aatatgatgt atttcaactc ataaaatata taaatacttc aaatgtcatt acaaatacaa
     5281 caacttgttg tactctactg agaagggggg tgtattaatg aaacagaagc aatatgcaaa
     5341 ggtcattaga gaaaagcgaa aagcactcgg gtggacacaa aaagaattag ctaaaaaaat
     5401 cttctctaca caacaggcag tagcaagatg ggaaaattct gtaacagaac ctaacctcga
     5461 tagcttaaca gctctttcta gagccctagg aacccctgta agccattttc tagacaatgt
     5521 tgacatagat tatgaggaag agtttttggc tctctatcgc tctcttagta ctgaagatgc
     5581 aattcgaaca attgactata tgaagctatt aaaaaggcaa gaaaatgaac gcaatcagct
     5641 attgaaagat tgaaaaataa ataacccacc gaactttaac ggtgggtgta ttgagatgaa
     5701 ataagattaa gagctatgga taacctgtct agtttaatat aattgggtct cttctattcc
     5761 ttactctccg tccatcatct cttgttacac ttgtaaattg ataaatagga actaattcaa
     5821 ctcctgataa tatcaattct tttattactt catctatccc tgcccctttc gctagatata
     5881 ctaaaaaact actgcttgct ttcacattgt atagtttctt aatatcctta gaagctcgtt
     5941 caagagtgaa tccttgttta acaaagtagc ctctgttttc tattaaagca tttttcacgc
     6001 tgttatccct gacatttcgt aggcgttcac aaacagtgtt aataagttct ttttctgtca
     6061 ttagatatgt cccttgccac gataagccct gtaaaacttc atgtgcttca tctaaaatca
     6121 attgtttttc cttgctaagt tctgatcggg aattttgagg aaatactctt ttagcctctt
     6181 tttcgttaaa acatatctta acccattcat aagaaaaata ttgatatgta aaatgaaatt
     6241 tttccagaag tggaaggata tcttcattca atttttgaat cacagaagtt gcattaaaaa
     6301 cgtctaatcg atagacattg cttctcttat gtttaaagtt tcctaacgct ttctcttcct
     6361 ttaacctatt taggtattcg agcatcttca aaggaacatc ttcatcatct aattttttta
     6421 tcaatcctat aaaagtcata agtgatagta acttattaca tttatctatg tcataagttt
     6481 taccatagta agaactcatt tttttagcta attgttcccc cgacaaaata caagtcacac
     6541 tttccttact atcatcaaaa aaattaacat cagaaagcaa gacatcatag acacgtcgca
     6601 tttcctctag ataattcctt attgtcctga aaagtttgtc tttcattgat tcaagagtgt
     6661 caaaaagtac ttttgattcc tctttcaatt ttcgaaaatg tgtaggatac aagtctaggt
     6721 tctctaatag ccaattaaat gtttctaccc gactgtcttt ctttaaaatt agcatcacaa
     6781 ctccaataaa attttcactg atatcacaat tactggaatg acaataaaaa atggaatgcc
     6841 cagttttact ggtaaaaata ctagcagagg gattatgatc gttgtgaaac agacatctta
     6901 agtttttact tgacttaagt aatttattca tatcaatggt taacaatctt tcataaatct
     6961 cattaaaaga catgtcggag gaatcaaaca ggcagtcttt aaaccactgt ttcatttctt
     7021 ctttgtcgtc attttttatc aacttaacaa aatcggtttc attgactagt tcatactctc
     7081 tccctgaatc actttgacaa tttttagaac atgtcatggt aaaatcaatc ggaagctcag
     7141 taatatctaa catgttgtct tcattaatta ttatcactgc atctgactta tatcctccaa
     7201 aaaacattct attcgaagca tttacattgt catcacaccc ggggatgttc tttttcaagt
     7261 attcgtaaac agcaaccatt ttaccatagt cagtaattgc ttcttttaat agaaagacaa
     7321 tcttgtattt ttctagattt tcagagtacc gaatactttt ttgtatcgca aacgcagaat
     7381 tatgaactaa attgatagat aaaacctttt ctatgcttaa gtatctacta tcatctttac
     7441 tcaaatctac taccttcccc ttctcatctt taacagtgtt atcgacatcc agaataatta
     7501 ctctggtttc cacaaaactc tccttgtcat tgcctttatt ctttgtcttg cttggaataa
     7561 atgattgtga tgaatttagt atctctacaa actcatctct tgtaacttct ctatagttat
     7621 ctaaacacct atctcttaca tcagtttttt ctttttttgt aactggcttc tctaataatt
     7681 tttctttatc tacataaatt ggaatattaa tcattgatgt ttccatttgt gtttcctcct
     7741 tataaaattc tgttaaagac taaaacatac agataataaa aacaaactct ttattactat
     7801 atgttttagt cttatttgtt tactcaacct ttataccgtt ccatgaaact atcaatatca
     7861 gattttttaa atctaatgac cgtatcaatt tttataacag gtaacccgta ttgagaaaca
     7921 tattttctaa tcgttcctac tgatacacct agatattcac ttgcctgctg atagtccata
     7981 tactctagag tgactccaga aataatgtct tctagcatag gctttagcac tgtaattatc
     8041 tctttcactt gttgttcaac ttgtatagaa acaatgctat caatgatttg tagagacata
     8101 tttccccctc ctttcgtgat tgcttgaaca aattttctaa gaattatctt cgtatttttt
     8161 gctcaaaata aaagtatttt gttattaacc gattaatcaa acaaaaaatg attaccagtt
     8221 catcgacata cacataatac ctcgataaaa aaggggtgtc aatagttttg taaaatttat
     8281 ttacaacacc ccttttttga ggtatactaa ttttaggagg tgtggtcaat atgataaaac
     8341 gtccaccaat aaattattta gaacgaaaaa agatactcgg aacaaaaata aaagctataa
     8401 gaaagagtaa aaaattaaca caaccagcat ttggtcttat gattaacaac ggtcaattaa
     8461 ttgacaaaaa gactatctac gaatgggaga agggaaccta tttaccaata ccagagcgat
     8521 tatcccgaat tgctgatttg ggaaatatga gtatagagga gttagtttgt ggcaatgtag
     8581 aagaatatat tttgggaatt attctttata gagatagcat tgtactagat ggtataacat
     8641 ttccagataa aaacctgttc cagcatcttc gtcaacagtt cccaccagta cactctaatt
     8701 tagatacatg gctggataga tattccaaat tagaaccaga gatgcaagaa tttattgcta
     8761 acaagacttg taataaagtt aaaaatgaaa aaattagtct tttcaatatc ttaaaaatag
     8821 aagaattatt catcaatgct attgtagaag aatttgacaa taacattctt ttcctcacta
     8881 gcagtataga agaactacta gaaagaatgg tagatgaatg gctacctatt caattgaaag
     8941 acatgtctta tcccgaagaa gctgtgagag aaattactga taatataaac aagctagaac
     9001 aaacgatttc atcaattggg aaaaaataca ctaagaaaaa aatgaaggga ggtgatacca
     9061 tctagtggta agtactcctt gtaaactaag aggagatgat ttcatggcaa aaatatcaaa
     9121 gtacaaaaag aaaaacggtc aagtggcgtg gatgtataaa ggacacattg ccaccgatcc
     9181 acgaactggt gaaaaaataa atactacgag aagaggtttt agtagcaaac aagaagctca
     9241 aaaagattat gacgagtaca gacatcaaat attatacggt gttaaaaaga aagcacctga
     9301 tatgacattt gaagacctgt ataatgaatg gataactcat cagcgtacca gtgttaaagc
     9361 ttcaacaatc gcaatctcag taagatacgc aaataatcaa atacttccag catttggtaa
     9421 gcttaaacta tcgaatatct ctgtcccata ttgtcaaaaa gtggtagatg aatggcacag
     9481 taaatatgaa agttacgatt atatgagaaa acagactgca caaattttac gctacggggt
     9541 tgcaatgcaa tatattgaca ataatcctat ggaaaaaaca cttcttccac gaaaaaaaga
     9601 gtatgagaaa aatcgtaaat tttactcaaa agaggagctt aataatttac tggatgcttt
     9661 taaagatttt ggtaacatga aacaatacgc cttcttcaga ttattggcat acacaggtat
     9721 gagaaagagt gaagtactcg ctttacagtg gaaagacata gacacgttta ataaagaact
     9781 acatgtcaat aaaactcttg ctgtagatga atttggtaaa gttataattc aatctccgaa
     9841 aacaagagct tctagacgag ttatctcttt agatactgag actctttcta tcctcaacaa
     9901 ctggaaatta cagcaaaaag aagagtattt aaaacttgga tacaatacta gctctaaaga
     9961 gcaacatgtt tttacaacag ttaaaaacac tctatacatt ccaaacactg ttaatgattg
    10021 gttaagatat attttgaaaa aatataactt gcctcgtatt acacctcatg ggtttagaca
    10081 tacacatgct agtttattat tagaagcagg agaatctgtc aaggtagttc aacaacgatt
    10141 agggcatgaa aatagtaaag tgacattaga catctatgca catattacaa ataatgcacc
    10201 taagaaaaca ggtcaagact ttgctgatat gatggctcat cagtaaaaga gctggtcaaa
    10261 atctggtcat ttctagtata caggcaaaac aaaaaagcta gaacccttat atatcaaggg
    10321 ttctagctcc tataacaggt ttacccaaca ctgccttcca atgactcttt tgggaatcag
    10381 aggaaagaat caggctttat agagatattt catctaacaa attactttag actgacagta
    10441 tatatcagca ggtactgtca tcgggaacgt agccaatatc gtatccaaaa cagcaggtag
    10501 agaagctatt tgaggattca agttattcta tttcaaccat gaagttaagt tcattaaaaa
    10561 taaagatagt tggtatttca ataatttttg tatagagtta atcactttat tgatgctaat
    10621 tcatcttgat tggtattata atcgtattca agttgcgtgg cgtgcttttg ctagaaaata
    10681 tataactgtt ctttataaag aaatataagg attaaacatt ttttatcata gagttttact
    10741 tatctataga attatgtctg ttcctaattc agtttgatga attaactgat aaaaaaatat
    10801 ctactattta aagatacagg gataagtaag taaaaaaata acatgtcatt agatagtaga
    10861 cagttccaac tctttattta ccttttttgt atgctgcact gtcaatccaa gttcctaaat
    10921 tgttgtatcc atcatcactt atataatcat attggccatc aataatttcg tcaaaccaca
    10981 aatattctcc atctggtttt tgcccaatta ttttaattac tgattgacta gtagttgtca
    11041 tctggttaaa atcttttatt ttacctatat taacggccaa aatagcattt cctcgcttat
    11101 aactctcctg gatttcatat ttaacatatt ctcgatcaag agtttcttta cctatcagca
    11161 ccacagtcac tgatgttcca attaattgat tatctatcca gttttttata gcaatatctc
    11221 cattacgttt aactttctca aattcagcct tatctacaaa accagcttcc tttgttcctc
    11281 gcaaagtcca gctgtttcta actaccattg ctcttgttac atctgcataa tggaaactaa
    11341 aaaaaaccct tctcaccata ttaatcctcc tgaatactat ttattaaact gacaatttgt
    11401 tcaacttttt tatctacttc tccttcagta tctaattttt ctagcgcttg aaatttactt
    11461 tttaaggaat catcaaaata atcactgaaa ttctcttgaa tcttatcaaa caaaacctta
    11521 cttgcacctt tggtaaatcc aatcggaact actatatttt cattttgaac agataattca
    11581 aattcttcaa tcattccatc tgctgtaact atttcacctg attcaagttt gtttccaaaa
    11641 acaaaaatac taatcccaga ctctgcaata atgttttctc gatatcttct ccactcatga
    11701 ggcatatcaa ggggaagtgg tcttaaagaa agtacgtctt gtatgttatt ttttcttaaa
    11761 tttcttctct gctttagaac tcctgaaaca atactattac caattccaag tccgtaacct
    11821 gatactattc tataaccgga ttcagaaagc ctatatgcta atttctcgac aaattttaat
    11881 cctttcgatt cagatgtaaa tggagtataa tcaacagcac ttcccgaaat aaaaatagtt
    11941 tttctcaaat acttttttct aatacttttc aaaatatcag taatctcaga ataatcatct
    12001 acttcaacaa cgtttatcga aaatctggac aaatcattga tttgtagtct tctttttgtc
    12061 agttcataat tatatctctc ttgatcaaaa aaatcctcag aatcgacaaa attttccttt
    12121 aatatttttc tcattataca ataatgaggt ctttggtttt ctctcaaaac ccatcttata
    12181 tctgataaaa ttctttctaa attagggtct gtaaaactaa atcctaaaaa gagaaaagtt
    12241 tttgttaaca aatctccttt taaagtttct ttaaataacg cgtacgaatc atcatcatat
    12301 ttttcataat catctcttgt tattactgtc gaactgacat catctatatc accatgcatt
    12361 ttataaacaa ttgtatccac atttggatta gttgttgcta actgagtata atttttctta
    12421 acctgagggt ttttataagc ttctcggatt gatttttcta ttagatgatc ataattagtt
    12481 gtccaataag tttcaatagg taaacttgct agtattcgat gattttcaga tatttctaat
    12541 tcttcaccaa aattatccat aagtatctga ttcaaaattc ctcttgatcc accattttca
    12601 tttttataat attgagccag agtaactaag tctgtttctt ttttagaatc caacccgatt
    12661 tctgttgcag gatcattaag tagttccggc caacttacat atccttgtga catcgataat
    12721 cctgcacctg caaatattgc tgcatttcct ttttcaatag cttcagagaa cctctttatt
    12781 aaaactttct tatccattct acccggttcc tttcgattca gtaaattgat tagagattag
    12841 tgaaaatggt gtttttatat aaaatatcta atgtattact tcctttagtg cattccacag
    12901 catctaaagc ccattttttc aaatcagctt ttcgtaaata agttaattca cttaaattta
    12961 aagaatattt tatttgcaga ttttcttgcg aagaatagtg ctttataatg cttctaacat
    13021 cctcggtgct catttgagga ttactttcca atcgtggatt ctttttttcc actattgaag
    13081 ctgtcgtcag ttcgctatat agccatggcg aatacgtaaa tttctgttca ttagtgattt
    13141 cattgctcaa actaattgaa ttaggtgtat taagaaaaaa cagacattct gtactatcaa
    13201 tcatattatt taaagctgta gaaagcatca tatgaacatg actagttgtt acatttcttt
    13261 tatcataatc atatgttttt gtttgttcct tatagcaata tttttggtct atttttttta
    13321 ataaatcaga actgtatccc caaaccgaag aatcaataaa tgcagtaaga ccaaaatttt
    13381 caaatagcca tgatgcaaaa cgtatagcta atttttcatc agcatgagag tgagatataa
    13441 aaatatctgc ttttatagtt ggaaaccaat ctttaataat ttcgtctgca tctagaattt
    13501 tgctgtcctt agaataataa tcaactaaat cattttcact ttcaaataga ttttctattc
    13561 tcttgttaat agatttttgg ttgtgatcta tttgatttac tacatgtgta tatgattgcg
    13621 agcttgagga gaatgcattt aagtcagcat ttgtaaaatc caattcatat gccttataca
    13681 aggatatccc tccattcttg tattttgatc cacaatttat taggcaacat aacagtatac
    13741 cctatcgtta catatcccat tcattattat accagtattt cttcgtgaca cataagggtg
    13801 taacataata atttcaaacg aaatgactac aagtagtcat tgaagcaaat cttcataaga
    13861 cacctgtaga atatctttga tggctttcaa ttgatccaac ttaatgtgtt ggcggccacc
    13921 ttcaatctta accaacgttt ccctagttat agcaatttta cgaagctgta ggtctctaat
    13981 cagctcggtt tgaccaattc ctttttctaa tcggactcgt ctaatattgc taccgattac
    14041 attttcttta tcaataattt tttcctcttt caagaatagc acaccttttg gactaaaatt
    14101 agtccttttt cttattaatc ttaaagattc ggtatgctac aatgggacta gtattagtcc
    14161 atattcaatt ttaaggagga atttttttga agaaatttgc aatcattcta acttgcgctt
    14221 tactcatcgg aactataagc gggtgtacca cttctgacac aagttctaca agtacggaaa
    14281 ctagtacaac aacctcagaa aagaattacc caatacattt ttttccggtt ccagatggat
    14341 ttgaagctta ttatcatgat aaaaaactaa atgttccttt atcagaaact gaatctactg
    14401 aaaagatttt gccaattgaa attgaaagaa atcaagacga tataaaacta aaagctgatc
    14461 ttcccttact gaacagcaca caaattgata gacatgaaaa tattaaagtt aatattgaaa
    14521 aaggagcgtt agcacaactt tatactgaaa aagttgaaca attttttgag gctggtgcca
    14581 ataaagactt ttcaaaaata agcgattatt cggataactt ttttaatgag acccaagatg
    14641 aaatcacgaa ctcaactttt atggctgaag atatgtacaa tatgaagttg aaaaaaataa
    14701 agtcgtatga ttatccatta aatctaacat taaataaagg gatactctct tttgtattag
    14761 caggttacgt tgactatgaa tatacagcag attatttgga gacgcccctt caacacgata
    14821 ataacgatat taattttaga tttatctaca attcaaaaag taaaacatgg ttagttgatc
    14881 aattgagcac tataaatacg ggatttcatg aattacctaa gcctgacaat gaaactgctt
    14941 tggtcattaa aacattctaa aaaagaaacg ttgaaggaat aattattctt tcaacgtttc
    15001 ttttattgtt tttcagttta cggtcttacc tgagcgaata atctgatttc taaatgattg
    15061 gaaaacttct tgtggttgat aataatctgt atctatttca aatgtttctg agaataattc
    15121 attgaatttt tctactgaaa tgatgatttt accattctcc tctcgactgt tttctattat
    15181 ttctgcctct aattcaaata aatctagtga cgaactaaaa tcataaatcc tgtcatattg
    15241 aacaaaaaaa tcaagaaaaa gttgctcaaa ctcttcctta tttatcacta gtgtttcaag
    15301 cggaacaact ttattttcat cagccattct tccaatttcc tcactttcat tttcaattgt
    15361 ccattgttgc ggacgtatca gattttctct atcatttttc agtgtataga tcacttgtaa
    15421 tacacaacaa tgctttgtaa acttattttt ttagttagtc gaatcttttt aaatgtgcgt
    15481 ttcataccat gcgcttgata tattttctcc tattttttaa atcgtttatc acaactttta
    15541 tcgttttttc ttctgaaaaa aatcttgttt acatcgttac atagtttcca aaaagataca
    15601 ttactagtag aaacaacaag attaatttta cttcccactg aaatgggaag tatattttaa
    15661 atattttttc tccttcaact tacactataa agtatcttaa tcacacgata tgctagccac
    15721 taaattcatc atatttgatt ccttttttaa gataatgtag catcttttta tccaataacg
    15781 caattgtttt taaggataaa tttcttaaga tggtacattt caaaatggca tttgacatat
    15841 gaaacaaaaa agaaagaaaa gagcataagg gaaaactgat agcaccttcc tacaggaagg
    15901 tggctaagtt ggctgtgcca actggttttc tttcaaaatc atttcataat ttttgatatc
    15961 ataaaaaaat ccattttgga cctattttcg gtcataattt agtacctact tttggtcata
    16021 gtttcgtccg tagttttggt catagtgact aaggcttttc tgttcacaaa attggtttaa
    16081 atttgctttc tttaacactt catttatatc atagcaatta taatgtttac acaacatcat
    16141 tcctaatttt aacggttgtt cctctttata ttttttaagt tctacatttt tttgcgttta
    16201 attacttttc tcttttcttt atattccgct ccaactttct ctttaatagt gataatagaa
    16261 ttacatattt ttgttaaact tccttaaaaa aattggatct cgattactca aatttgcttg
    16321 caggcttttc taattgcttt gttttttctt cctaattatt tgattttatt tccattttct
    16381 tctagtgaaa atttattatt tttaataatc gtacgcgtag aactgatttc attttttgta
    16441 tctgtttgat tatctaacgt ttgaaattca aagttttgat tggctttatc aatatctttt
    16501 tatactactt tatttgcaag atatattttc ttgcttaatt tggtcatagt ttcattcgtc
    16561 acttcggtga tattttttta atttgcaaat aaaaagagtt aaaccgatat acattaggtt
    16621 caactctttt gcaggtttca tgggtgtact atcactttta atctgataga tgtaaacctc
    16681 tctttatctt tttgttactt caattttcaa caatagctcc tttataggtt gtcaatattg
    16741 ctctacgtat tctggctttt taacccatta tttctctaaa gtggaagaga ataatcgctt
    16801 aatccccact aattccttgt cgtaaattca tgtcaaatac aatttttaaa agccatttaa
    16861 ttcatggatt atctcttcac ttttttctag ataacaatat ttcaagttgt tttttatctc
    16921 atgtttcatc tttaattctt cttgaatcat cagttcaata taattagtga ccgtgatttt
    16981 ttcatttgtt gcgttcttta ctgattcaca taattcgtca agttctaaga aatcatgcgt
    17041 actaatcttt agaattaatt tcatgacaat tccccctttt atttttttaa tagattatcg
    17101 aaaagcggat taggatcatt aagtgtatct ctgaataact cgttgtcttc ataggtaaat
    17161 cttcgtcttg gttttgatcc cttatcattt tcacggattt cactatcaat aatcactgtt
    17221 tcatgatttg aatcaaattt tttcgctgac tttctgtctt caacgatatt gattttttgt
    17281 gttttttctt tcatttctcc actatctttt tgaacgttct cccgaacatc tactgttttg
    17341 aatccttgac tacttgtaga actttgtaca ttctctctta catccattga tttaaaccct
    17401 tgactacttg tagaattttg tacattctct cttacatcca ttgatttaaa cccttgacta
    17461 cttgtagaat tttgtacatt ttctcgaaca tcaattgtct tagtaccttg accatttgaa
    17521 gagctttgta aattctctct tacatcaaca ttccgtccga catgaccatt caatgaacct
    17581 tgaatatttt ctcggacatc tactgatcgg ccaccttgac tacttgtaga attttgtaga
    17641 ttttctttga ccaatttttc taatccggta tttgagtttt tagcttcttg gattctttct
    17701 ttggtcaacg cttctttttc gtccgtatta gctcctgtac gcccttctac acgtttcctt
    17761 aacatttcct cacgattcat tgcttcaggc gtgtatttag cttcttgtcg cttctgatta
    17821 attaattctt cagcagactt agcttgaccg tgcatagcat ttttacgttc ttcaatatct
    17881 tgttgaactt tttgctgaat tgcacttaca ggattattat tcgattcagc attatttttc
    17941 attgcttcac gcatacgttc agaactagac ataattctat cggcattttc aaccttagca
    18001 ccatcttttc tatccgaaag acgtgttggc atggaatcag catattttcc agtttcatct
    18061 tctttatttt tagctaacat aggtttgcta tttttattaa tagcggacac tgtaccatca
    18121 tctaaacctt ctttgaactt attcttggta tcattagcca tatcacgcat actcttaaat
    18181 ggttttattg ctctttcact agccattgta gctccatctg aagctaaacc tgataatcca
    18241 cgttcatggg catatcccaa agctcttcca gttttgccag ctttttttga tagagtttcg
    18301 ccgaaattct tttctggttt tcgatcttct ccttctccac tgtctgatcc atttccattt
    18361 ccgcttcctt tagcacgatt aaatccagtt gatccttttc taaacagcat tgcgcccata
    18421 ccaaaagcag aagcaagttg cccatagcct tctttgagtc caatatcaac accaaagtat
    18481 ctcatgactg ttccactgcc ttttatcagc acaaacacag cacagatata agcaattgtt
    18541 tttataaaaa tatttgtgga gataccttgt ccagcattta aaaaattgat aaacatagca
    18601 aacatagata gtccaaaccc ttgaaatcca actgttaagt aacattgtaa aatatcggat
    18661 aaaacaactt ttgaacgttg tcctgtttca atatctgtcg caaaaacaag aacacctaac
    18721 acacgtttaa atgcaagttc taatattgct gtaatgatca caaacgcgct gaacacatag
    18781 gcgattgcca acgctgtcaa cccaatcgaa atcccccaaa gatttgcttg atatcgataa
    18841 taacctgatt tcaagctatc agaaaatgtt gataagaagt tatcagaaaa ctttgtggca
    18901 acaaattcat tattagaatt ttcaactaa
//
LOCUS       DAFEKH010000054        18840 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.056, whole genome shotgun sequence.
ACCESSION   DAFEKH010000054
VERSION     DAFEKH010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18840)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18840)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18840
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.056"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(21..251)
                     /locus_tag="LP386_002200"
     CDS             complement(21..251)
                     /locus_tag="LP386_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919413.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
     gene            complement(687..1253)
                     /locus_tag="LP386_002201"
     CDS             complement(687..1253)
                     /locus_tag="LP386_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBL1919414.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1253..2209)
                     /locus_tag="LP386_002202"
     CDS             complement(1253..2209)
                     /locus_tag="LP386_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HBL1919415.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2209..2865)
                     /locus_tag="LP386_002203"
     CDS             complement(2209..2865)
                     /locus_tag="LP386_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBL1919416.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3235..5253
                     /locus_tag="LP386_002204"
     CDS             3235..5253
                     /locus_tag="LP386_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL1919417.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    5323..5529
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5680..8094
                     /locus_tag="LP386_002205"
     CDS             5680..8094
                     /locus_tag="LP386_002205"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HBL1919418.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8442..9995
                     /locus_tag="LP386_002206"
     CDS             8442..9995
                     /locus_tag="LP386_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBL1919419.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10376..12160)
                     /locus_tag="LP386_002207"
     CDS             complement(10376..12160)
                     /locus_tag="LP386_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1919420.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12175..13896)
                     /locus_tag="LP386_002208"
     CDS             complement(12175..13896)
                     /locus_tag="LP386_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1919421.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            13996..14757
                     /locus_tag="LP386_002209"
     CDS             13996..14757
                     /locus_tag="LP386_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBL1919422.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQFLLTNTDENNIRTEYYHAWIEMKK"
     gene            15724..15992
                     /locus_tag="LP386_002210"
                     /pseudo
     CDS             15724..15992
                     /locus_tag="LP386_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            16664..>18840
                     /locus_tag="LP386_002211"
     CDS             16664..>18840
                     /locus_tag="LP386_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919423.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVL"
BASE COUNT         6185 a         3343 c         3771 g         5541 t
ORIGIN      
        1 ctcattaaaa agcataacca ttactccgat ctgtttttaa aattagtttc tacctctaat
       61 atatatcgag tttttatttt gccttcagag aatactgttt ctttttttgc agttacaggt
      121 tgtttatttt cggaaaaagc taatatagct aagattgaaa catccatctg gaatttatct
      181 tttttactgc tttgatcata aaagtctgca tattcatcac tgatattttt tctaataaat
      241 tcttccatca taaaaatcac ctcaaaacga ttatacgaac ttacgttctt gttgtaaagc
      301 gatatttgag gggcaaaaaa ggggcataat ttgactgata ttaagttagc tattgatata
      361 tgaatgacat acaaaaatat aaaatctttt aaaaatgctt atatatcaat gtttttgcca
      421 ttcttttata tatctgttat atgtcaaaaa aatgtgttca atttcaattt gtatttgaat
      481 aaagaggttg tgaaaaagct gtcctgcatc aagtaataag aacagccaat caaaaacagc
      541 ttctcatgtt tttgatttgg ttggacttat taccgcagat ataagctttt gagcaccgtg
      601 aataaagagg ttatgaaatc aacgctctaa cctgagtatt agagaaaaaa acgcaaaaca
      661 tatcatttat gttttgcgtt ttttatttat ctttttttct caatacaata taaaataggc
      721 ggctggttct tttggttgat aaaccgataa ttcagcacat tatatgtttc ctgtggcagt
      781 ttggaacaaa aagaatcaac catatccagt tctttttctc caccttcatg accatagtag
      841 acgacaagga tcaatcgtcc gcgaggcaca agtcgtttca atatttcttc catagctgtg
      901 cgtgtagtct ctggcatagt gatgattgct ttatcacttt ttgggagata ccctagattg
      961 aaaatccctg ctttgagatt ttgttgttca gctatcactt ctcctaacgt ttcgtggcct
     1021 tgtagaaaca atgagacacg ttcttctaac tgacgctgtt ctagcctttc acgagtagca
     1081 tcgattgctt gttgctggat atcaaaacta tagacatgac cagtttttcc gatgtgttct
     1141 gctagaaaaa ccgtatcgtg gccattgccc atcgttgcat ctacgacgtg atcccctggt
     1201 tgcaagattt cttgcagtaa tgtatggctg aaatgcaaag cagtttgcaa catcagacgc
     1261 tcaccttttt ccgtacatca tattttcctt ggaagctatc tctgcgaaga agttcttcat
     1321 caattgcatt caagacttcc cattttttca agctccacat tggtccaatc aaggaatccc
     1381 acggcgcatc ccctgtcaaa cgatggatga tgatctcttt tggtatcatt tccagctggt
     1441 cgcaaatgac attgacatag tcaggacggc tcattaattg aaggcgacct tcatgatagt
     1501 cccgcaacat tctcgttttg cgcatcagat gcatcaaatg gagcttgatt ccttggatat
     1561 ctgaatctaa aatggtgcgt ctgacatttt ctttcatcat ttctaaactt tcgcctggta
     1621 atccgttgat caaatgcgta caaacacgga tattatgttt gcgtaattta gccacgccat
     1681 ctaaataagt ttgataatca tgtgctcggt tgatcagttt tgaagtttct tcaaaagttg
     1741 tttgcaatcc aagttctacc cataaataca tccgctcgtt cagttcagca aggtaatcaa
     1801 ctacttcatc tggcagacaa tccggtcgtg taccgactga taatcctacg acacctggta
     1861 aattgactac ttgctcaaat cgttctttga ttatttcaac tggcgcatgg gtgtttgtaa
     1921 aattttggaa ataaacgatg tattgttgga catgaggcca tttttgatgc atcatgtcga
     1981 tttctttctg gaattggatt ggaagagggt cttcaggtgc aacgatcatg tctcccgaac
     2041 cagatacact gcaaaaagta caaccgccat gggcaacagt cccatctcga ttcggacagt
     2101 caaatcctcc atcgatcggc accttgaaaa ttttcccgcc aaactcattt cgtaaagcgt
     2161 aattccaaga atgatatctt ttatttcctt ctgaataagg aaaagtcatt aaaagtcctt
     2221 ctttctgtaa gagttatcta tttgttttct tttttctcta tacactggat aagtcaggca
     2281 cagccaagaa agactgagta agtagccgcc gatgatatca gtaggaaaat gaacgcccag
     2341 ataaatgcgg cttatcccga cacttactat aataaacatc atcagcaatt gaagcaatgt
     2401 gcgtaaggtt cttttttgaa caaaagctgg aagcagaaat agtaaagaac cgtaaagaat
     2461 catactgcct gctgcatgtc cactagggaa actgtaactt gtttcaacta ctaagtgcgc
     2521 caatgaagga cgctctcgca tgaaaaatag tttgatcacc gggttgatga ttccagcaat
     2581 tacaataaat ccagaaacga accaaaatgt ttctgccctt tttttcttat accacatcca
     2641 taaagccgca caagcaaata aaatgatgac ggtaagagga ttaccgaatt tagtcataaa
     2701 gagttggtag ctgttcagat caggataaga agctctgaca atgcctgtaa accactgatc
     2761 gaaaccagaa agccacgaca gatggaactt tacgatccag cccaaaatga aaaacaggac
     2821 aagaaagaag ctaccagcca cctgaaatga tgttttatat ttcatacaat tcctcctttg
     2881 aagcaatgac ttattatagc atttttggtc cagcgaaaaa aacggtaaag agataaaacc
     2941 aatgtatgat tcctctttga ataaccaata ttcttataaa aaaaataact gtaatcggaa
     3001 agacattttt tggtaatgca aatgaaatgt tagggaaata aaatcagtgt ttttcgaaat
     3061 ccttttaaac aagaacgtag acgtaggaag aacttgaaaa tgaacagaag ttgttcatta
     3121 cggtaaatta caatatgatt acaaaaaaca acaaagctct taaataactt ttaataaata
     3181 ttaagagaag ttataattat taataataga taaattgaag ttggaggata gaagatggaa
     3241 aacattgcaa gaaaagaacg gagacgttta gaacagacca aacgttttcg aaaagcaaaa
     3301 cgaggggcag caatcgtggg aactgcgatg gtaggctgtt ctgtcgctgc cccattagta
     3361 cagccggttc ctgttcaagc ggatgaaaca cctgttcagt tcggcgcaag aatcaataca
     3421 gcggcattta tcacagaaat tgctacttat gctcaaccaa tcgctcaagc caacgatcta
     3481 tatgcatcag tgatgatcgc acaagcagtt gtagaaagcg gttggggcag tagtgcgtta
     3541 tctcaagcac cttattataa tctttttggg ataaaaggca gctatcaagg acaaaccgtc
     3601 tacatggata cgcttgaatt tttaaataat caatgggtaa ataaaaagga gcctttccga
     3661 caatatcctt cttttgctga atctttcaat gacaatgcct atgtacttag aaatacttca
     3721 tttggcaacg gttattacta tgccggtact tggaagagca acacgaaatc ctatacagat
     3781 gcgacagctt gtttgacagg gcgttatgcg actgatcctg gttacgcagg caaattaaat
     3841 aatatcatcg caacttacgg attgacccaa tatgatacac cagctagcgg aaacgcaggc
     3901 ggtggagcga ctacaggtgg caataatact ggaagtgcag gtagtactgg cggttcaagc
     3961 aattctggta atacaaactc aggttcagca acttcgacca cttatactgt ccaatctggt
     4021 gattctgttt ggggaatctc aaataaattc ggtatcacaa tggatcaatt gatccaatgg
     4081 aacaacatcc aaaacaattt catttatcca ggacaaaaac tgacaatcaa aggtagccag
     4141 gaaaatggct cttcgacgaa taattccggt aacaatacca actcttcagg aaatgctggt
     4201 acatcaaacg gaggacaaac aactggtgcg aaatacactg ttcaatctgg tgattctgtt
     4261 tggaagatct caaatgatca cggaattacg atggctcaat tgattgaatg gaacaatatc
     4321 aagaacaatt tcgtttatcc aggacaacag ctaatcgtat caaatggcgg ttcttctaat
     4381 gctggagcaa atactggctc aaatactggg aatacaagtg gctctagttc gtccagctca
     4441 agttcttcta atacagcttc aggaacgaaa tatacagtta aagccggaga ctctgtttgg
     4501 agcgtctcaa ataaatacgg aattacgatg gctcagctaa tccaatggaa caatatccaa
     4561 aataacttta tctacccagg acaacaactg actgtttcaa acagtggatc aacaaacagc
     4621 acgtcaggta atacaggttc gtcaaccaat acaaataaca gcagttcagt taatactggc
     4681 agcagttcgt ctcaaggcac ttataccgtg aaagcaggtg aatctgtttg gagcgtggca
     4741 aataaaaacg gcatcacgat ggatcagtta atcgaatgga ataatatcaa aaacaacttc
     4801 atttatccag gacagcaatt gatcgttaaa ggtggaactt cggcaaatac aaatacaggt
     4861 tcaactactt ctgcagcgaa accaaataca ccgaatacgt ctgctacgac aagtacatca
     4921 tccactggta atacgatgta taccgtgaaa gcgggcgagt cagtttggag cgtagcgaac
     4981 aaacatcata tcacgatgga tcagttaatc gaatggaata atatcaaaaa taatttcatc
     5041 tatccaggac agcaagtgat tgtgaagaaa ggttcatctc aatcaacaaa ccaacaatca
     5101 gttactggtt cgaaaaccta tactgtgaaa tctggagaat ctgtttggag tgttgctgac
     5161 agtcatggaa ttacaatggc tcaactaatc gaatggaaca atattaagaa caactttatt
     5221 tatccaggtc aaacgttgat tgtagctaaa taaaatagct gttcgaagaa ataacgattg
     5281 aattccacaa aaatatttgt tactataagg ctacttaaat atgacaacac ttgaaaagga
     5341 agtagtaaaa agactgaagt ttcagagagc gcatggctgg tgagaatgtg cacggatgct
     5401 tttgaactcg cctttgagtt gcccttgctg aatacccgag taagcaagcg gcggtgacgg
     5461 ccgttacaac gttcgaggcc ttttcactaa ggtaaaatta ggtggtaccg cgtagattac
     5521 gtcctataaa aagagcaatc tttttatagg atttttttat ttcttttgtg aagtttgaga
     5581 aaacaaagca aaaggaaata aaaataaaca gattctgccg gttttttcgt tatatttata
     5641 atagaaacaa gtgttttcaa tagaacagga ggacagcaaa tgagttacaa tcataaagaa
     5701 attgagaaaa aatggcaaaa atactgggca aaaacgaata ctttcaacac ccatgatgat
     5761 cctgaaaagc caaaatttta cgcactggat atgtttccct atccatccgg tcaagggcta
     5821 catgtagggc atcctgaagg ttatacggca acggatatcc tttcacgtgt gaaaagaagt
     5881 caaggataca acgtgctgca tccaatgggg tgggatgcat tcggtctgcc tgctgaacaa
     5941 tatgcgctag atacaggaaa cgatccagct gagtttaccc aaaaaaatat cgaaacattc
     6001 cgacgccaaa tcaattcttt aggatttagt tatgactgga atcgcgaagt gaatacaact
     6061 gatccggagt attataaatg gacacaatgg atctttacga agctttatga aaaaggtcta
     6121 gcttatgaag cagaagtagc ggtaaactgg gtacctgaat taggaacagt tatttcaaat
     6181 gaagaagtga tcgatgggaa aagtgaacgt ggtggctatg atgtagtcag aaaaccaatg
     6241 cgccaatgga tgctgaaaat cactgcttat gctgatcgct tattggatga tctagaatta
     6301 gttgattggc cagaaagcat taaagaaatg caaagaaatt ggatcggtcg ttcagtagga
     6361 gcaaatattg aatttaaagt ggctggtacg gataaatcct ataccgtatt tacgacacga
     6421 ccagatactc tattcggtgc aacttactcg gttcttgcac ctgaactaga tcttgttaga
     6481 gaaattacga cccctgaaca aaaagctgct gtagaagctt atatcgaaga gacagctaaa
     6541 aaatcagatc taaagagaac ggatcttgca aaagaaaaaa caggagtatt tactggtgct
     6601 tatgcaatca atccagttaa tggcaaggaa atcccaatct ggatcgccga ttatgtatta
     6661 tcttcatacg gcacaggagc catcatggct gttccagcac atgatgaacg tgactttgaa
     6721 ttcgctcaaa ctttcggact agaaattctt ccagttatcg aaggtggaga tgttgaaaaa
     6781 gctgcttaca cagaagatgg tacgcacatc aactctgaat ttctagacgg catgaacaaa
     6841 caagaagcaa tcgataaaat gaatgaatgg ctagaagaaa atggcgtagg gaaaaaagaa
     6901 gtcagctatc gcttacgtga ctggctattc tcccgtcaac gttactgggg tgaaccaatc
     6961 ccaatcatcc attgggagga cggaacagtc acagctgtcc cagaagaaga gctaccatta
     7021 cggttgccta agacaaaaaa catcaagcca agcggtactg gagaatctcc attagcaaat
     7081 atcgaggagt gggtcaatgt cgttgatcct gtaacaggta aaaaaggccg tcgcgaaacg
     7141 aatacaatgc cacaatgggc aggaagctca tggtattacc tgcgttatat cgaccctcat
     7201 aacaaaaaag aactagcaga ttatgaaaag ttgaagcgtt ggctaccagt tgacatctac
     7261 attggtggag cagaacatgc ggtacttcat ttactatatg cacgattctg gcataaattc
     7321 ttatacgata tcggtgttgt tcctacaaaa gaaccattcc aaaaactata caatcaagga
     7381 atgatcttag gcgaaaacaa cgaaaaaatg tcaaaatctc gtggtaatgt agtcaatcct
     7441 gatgatgtgg tcgaaactta cggtgcagat acactgcgca tgtacgaaat gttcatgggg
     7501 ccattagatg cttcgattgc ttggagcgaa aatggcttag aaggaagccg taaattcttg
     7561 gatcgtgtat ggcgtttgat cgttgatgag aacaataaaa tgcgtgaccg tatcactaca
     7621 ttgaatgatg gcaagcttga taaagtgtat catcaaacag tgaaaaaagt gacagaagac
     7681 tatgaaaatc ttcatttcaa tacagcaatc tcccaattga tggtctttat caatgaagcc
     7741 tataaagtgg acgctctgcc ttatgaatat atcgaaggat ttgttcaact actcgcaccg
     7801 attgctcctc acatgggtga agaactatgg gcaatccttg gaaatgatgg tggtatttct
     7861 tacgcaccat ggccaacata cgatgaagca gcacttgttg aagacgaagt agaagttgtt
     7921 ttccaagtaa acggtaaagt tcgtgcgaaa agcaatgttc cccgagactt aggaaaagat
     7981 gagctagaaa aagcagcatt agccaatgaa atagtgcaag aatatattga aggcaaaaca
     8041 gtcagaaaag ttattgcggt accaaacaag ttagtcaata tcgttgctaa ttaattggct
     8101 ctttgtcaat aaggactgat gagttgtgca aaatcaaatc tgggccagaa tgaacttcat
     8161 tctgtctcag attttttgtt atttcaaatt gattaattga ttgatcaaaa aggttttgat
     8221 tttcatgttc tcaaacacgt tcaatgtctt tttcttctga atggtcttgt aagagatctc
     8281 tgtaatcatc aaatttttgt ctattaatct tagtattttt tgatgtataa actacctgaa
     8341 attgagagta cataccaaat tcataaattt tttattagtg ggactagtga ttgtatggat
     8401 tttgacgcat aatgaatgaa gtatgagaaa aggagagaca aatggatcaa gaactattta
     8461 ttatcgaagt attatcagct aaacaaaaaa ttatcgagaa agcgaaaaaa agagcgaaaa
     8521 gaataatgtt caagctttta agcttagtat ttttctctgg tttgcttttt ttcggagctg
     8581 tatcgttcct atatcgccat atgagtgcag tagtccgttc agctgaaggg atgcaaaaat
     8641 taaataattt gtatcacttt tcgtggggag ttggcggaat aacaattgtt gtgcttattg
     8701 tttttcttct acttatttgg ctccgttacc atcaattgtc gcgtcatttc gatcaatggc
     8761 ttagtcaaag agcacaacag tttttacata ataaaccaac ttctcaagat gatgactatc
     8821 tttattttga gaagacttcg acgagtcaag cttttcggat acaaaaaagt gattgccagt
     8881 tattgctgag atcacttgat gatttaccta tctacttagg cgaaagcaaa tcaaaattcg
     8941 gaatgaacac attccatatt tttttactag aaaacgaacc cagatgggaa aaaagccagt
     9001 cttcgcctgg tggatacctg acaactaaga tgagtacatt agtcactggt tttttcctca
     9061 ttcttttagc tggaacaatc tattatggga gatacactca gccaaaaatg tcttctcata
     9121 taaatgctgc ttctcacatg acaatgaact caactaacga tacgcatata caaaagacaa
     9181 atgaagggtt gttagctgat cctaagcaaa aggtaaattt gacaacacaa aagataaatg
     9241 atctcaaact tgatacagag acgcactctc tctatatgac aacagatagt ggtgctaatt
     9301 gggtatttgt gccgattgat tcgcaatggt tgcgttttgg cgaatacacc ctgacaacgg
     9361 ggctgattcc tgaaggttat tggatggaca acacatatga tatttccgcc gatttctcat
     9421 ggtttatcta ttcttctggg gatgatgtac gtctgctgac ttcaagagat aatggtaaaa
     9481 catggcaaac gtctattatc acccaatcag ttcagccgat acgttatcga aaagcggtat
     9541 tttatggcaa cgatggtcta tttatctgta catcagccag tgggatgtct gcagaaactt
     9601 tgtacattta cactactatg gatggcggaa tcacttggat aaaaagtgga agtacaatga
     9661 tcaatcagcc agtacaaaat gtcagcttcg ttacaacttc tttaggtttt gtttcgacac
     9721 gtgaaagttt gttttataca aacaacggag gacgctcatt caaagaatca gttctgtcga
     9781 ttccggaaaa ctatcagaca ggggggatag atctttttca atcaccaaat gaagttactc
     9841 aaataagcgc gaatacgtta gagacaaaat tttatttgtt gaaaaaagga ccaatcgatg
     9901 cagggaaaat gtttgcctgc ctcttccgtt caactgataa cggggaaaca tggcaattcg
     9961 ttcagcaact atcgcaagta gaacaaggag attaaagaag agagattgtg agcctgacgt
    10021 tcagcaccga gtcacaagaa acaaattcaa aaaacagctt ctcatatttg ttgaatagtg
    10081 taactcgtga ttcggagttg acaagagcaa caagaagcga ttttgaagta tagcttctcg
    10141 tattttacaa gatcgtgtct tattgccgat aggttgtctc ttgaacaccg tttattcgta
    10201 aaaagggatt gtgacaagtc ttttgtcact acttaccgaa cgaaactgaa ggagctatcc
    10261 aaaaagtatc attagtatta ttctttgtgt ttctagtggc accactagta catttaaaaa
    10321 agctatcgat catggactaa tcatacatga tcgatagctt tttagataat gtttgttacg
    10381 ctatctgaaa ttgactatta taaagactgg cataaagcgt tggtgattgg agtagttcag
    10441 aatgtgttcc tttttcgacg atatcgccat tcttcattac aaggatcatg tctgcatttt
    10501 caatcgttga caaacggtgt gcaatcacaa aacttgtcct atcttttgtc acagcttcca
    10561 ttgcttgctg aatcaatgct tctgttcgtg tatctacgct agaagttgct tcatctaaaa
    10621 taacgacagg aggattcgct agaatgactc gagcaattgt caataattgt tgctgtcctt
    10681 gagataacgt gccgttttcg ctagaaatga tcgtatcata tccgtctggc agtgttcgaa
    10741 taaagtgatc acattgtgcg atttcagccg cttcgataat ttgttctctt gtggcatcca
    10801 ttttcccgta ggcgatatta tcagctaccg ttccttcaaa cagccaggta ttttgtaaaa
    10861 ccatcccaaa agaacgacgt agttctccac gtgaaagctt ggtaatatca agaccgtcga
    10921 attcgatctt tcctttattc agttcataaa aacgcatcag cagattgact aaagtcgttt
    10981 ttcctgcacc agttggacca acgatcgcta ccgtttgttt tggctttact gaaaaatcga
    11041 cttgattcat caatatttta tctgatgtgt aaccaaactg tacatttttg aaagctattt
    11101 ttcctttcgg ttgttctaaa agtcttgcat ctggaaggtc tggaatttca tctgtttcat
    11161 ctaatatctc aaatatccta tcgattgctg ccattgcgga ttggatcgag ttgatcacat
    11221 aagaagcggt agaaattggt tcagaaatct gattgatgta ctgaagataa gcttgtaaga
    11281 agccgatcgt cacaccacct gatagaacaa gcatagcacc gaataccgca cttatgatga
    11341 aggcgagttg attaatgaaa cgaatggccg gatagatagc acagttcata aattgagcac
    11401 gtttaaaagc gttgtattgc tttttattta cttcgtgtat agcagcttct gcatgagctt
    11461 gctgattgaa tgttttgacc actagattac cagctaagat ttcttccatt cgattattta
    11521 aaacacccag ttcatactga ttctgttcag aaatctgttt gtttttgttc gcaatcttag
    11581 ttgtaacaat tgaactgcca acgatcagca ataagacgag caaagtaagc ttgctttcga
    11641 tataaaacag catcagacca gcagcagcta ttgttacgac agaagtaaaa aattgattga
    11701 tacctgtcaa taacacttga gaaagttgat tgagaccggt agttgtccga ctaatgatgt
    11761 cacctacttg atgattgtca aaaaacgaca tcggtaatgt tttgaatttt tttgtgattt
    11821 cttttcgcac cctcaatgtg atcttttcgc ttaacgctgc cattgtccgt tcctgaataa
    11881 atgaagtgat gctgcttaag actgaacagc cgatcagcaa taagacaggg aacaacaatg
    11941 cttgtttgat atcactgaaa gaaagctgtc caatacctgt ttttcttatt tctgataaga
    12001 gatcatcgat cccgattccc atgatcaagg gcatggctac gactaatagg ttcccgaata
    12061 aactgcatag aaacaatccg taaaaatatt tatgttcagg tttgatcatt ttccaaaaac
    12121 gtatcaaagc acgcgtgttc aacgtttttt tcttttccat cgtatccctt ctttctatat
    12181 tccttgtgat tttgcaaact cctgataagt ttggcaatta gacagtagtt cttcatgagt
    12241 accttgtcca acgatttttc cttcatctaa aacaatgatg ttatctgctt gttggattgt
    12301 actgaggcgt tgagcaacaa tcacgagagt tttctccgac atgtgtttat gaagggctgc
    12361 tcttaatgct gcatctgttt tatagtctaa agcggagaaa ctatcatcga atacatagat
    12421 ctctgctggt ttgatcaacg ctcgagcaat acatatccgc tgtttctggc cccctgaata
    12481 attagaaccg ccttgagcaa caaagctgtc caatccgtca ggaagggtgt ccactagttc
    12541 ttctaattga gcgatcttga tcgctttaga caactcttct gttgaggcat attcatttcc
    12601 catctgcaag ttgcttaaaa ttgtcccgct gaataagaaa gccttctgag ggacataact
    12661 gatgtgggag cggatctgtt cttgagtcat ttgagtaaga ggaataccac caagggttac
    12721 ttttcctatc gtagggtcac taagtctcaa gagaagtttc gccaaactac tttttccaga
    12781 tccggtcccg ccaacgatcg ctgttgtttt tcctttaggt attgtgaaat caatatcttc
    12841 tagaactgga tcagagattt cagtatattt aaatgtgaca tgttcaaaag cagctgcatt
    12901 tgtctgatca aaggttggtt cagctactgt tttgatcgtc tcttcctcaa tttcgatctc
    12961 tgcttgcagt atttcttcta tccgtcgtaa tgaggcaaac gatttaggga taatgaccaa
    13021 taccatagct gcgatcatca agtaagcaag tgtcagcata gagtattcga ctacagcagt
    13081 cacgacaccg atttgtaatg ctccttctgc tacaagattt ccgccaaacc acaaaataga
    13141 agcataaacg attcccatga gcaaaaaagc aattggagtg acccaagcaa atattcggtt
    13201 cactttgatc atttgattag catagtcagc aaagctctta ttcgttcgct tttcttcata
    13261 tgattgatta tcaaaggcac ggatcatatt aatcccagta aagaattctc tcaatgtgat
    13321 ggtgatccga tccatttttg gctggatact caaagataaa ggtgcccctc gtttcatcag
    13381 tcgataaaca atccatacat aaaaaacaac agagatcaat gtaacccatg ttagtaatag
    13441 agaataacga aacatcatga gaatggtgaa aacgcaaata accggtgctg gtaagatcat
    13501 ttggcaaaat aaaacaatca tttgctggac attatcgaca tcattcgtca ttcttgtcaa
    13561 aagagatcca gaactaaaac gactgatatc cttcattgac agctgttgga atttacggaa
    13621 atatttctcc cgcgtttgga atccaaacct agcggaagcc aatgctgaaa agtaactaga
    13681 ggcaactgca gcgattgttc ctagaaacgc tacaagcagc atttcaactc caattttttt
    13741 tataactgag gcttcgccac ttgctatacc tgtgtcgatc agctttgcta ctaattttgg
    13801 tacacctaat gtaccggcga tttctaaaca gatcatcaca aaggtaagga gagcgagtcc
    13861 tttgtttttc tgtaagaatg tttttaagat agacatatta ttcctccttt tttcctgata
    13921 cttttcgatt ctataccttc aagtaacttg aaggtcaata gaaaaaagaa taaactgaaa
    13981 aagaggtgag aaaaaatgaa aaaaatgtat acgattggcc aagtatcgga actatttgat
    14041 ttgccaaaat caacgatccg ctattgggat gaacaaggat taatccgttc aagtagacaa
    14101 gaagagaatg attatcgatt gtttgatatc gatgatattt ttatgcttta tgatatcgtt
    14161 ttttatagaa aattagatat accgatcaaa cagatgaaga atttatatgg aaaaacattg
    14221 acggagttat atgagacact tgatgaaaca gaaagaagaa tccataaaga actggtggtg
    14281 atgaaacaaa aacaaaaaga gataagggag caaaaaaaac agttgaaatt gatgatcgat
    14341 acaaacgagg aagaatttcc tgtagaagag atcccttttg actgtatgat ctcaacggag
    14401 tttgaagata ttgtggaaat caaaaaattt ctacctaact attcaagctt tgggatgatg
    14461 agtatgccag cttccagttc acagacgatg tatggatttt ttatcgaccc tagtgaagta
    14521 catttattta ctcaagacgt gatttgggag aaaaaagata cggctgttta tcgtcgattc
    14581 ttattgaaat ccgagatgaa ccatgcggaa cgtaataata ttttagaaat cagagaaaga
    14641 atgtatgaaa aaggatggaa aacaggagaa gtgatcggcc agtttctatt gacgaatacg
    14701 gatgaaaaca atatcagaac tgaatattat catgcatgga tagaaatgaa aaaataggaa
    14761 atatgtgttt aagataactc gaaaatgatg gttgttttag ttataaagaa aaattttctg
    14821 gttcgattac gggtttaatg tgggggatta ttagtcgtgg atagatagaa ttttagtttt
    14881 ttagaggaaa tatgtcttta aaaatggaat ggttgcaatt cttagcgata tatacgatgt
    14941 aattgtcctc ttaaaaaagt atggaaaaat aattgtattg ggtgttatgt ataattcatg
    15001 gtgaactgag actaatgaga agaaaaattc atattgttat gagtgagatt gtatcagatg
    15061 agaatgataa attaaatagg tgcataaaag cattacactt aaaatacatt gttgcttaca
    15121 ttattacaat atgttaataa ggcaaaaata aatagatgga ttgaataaac atatttttta
    15181 atcaaatagt ccctactgtg actttcctca gctatcggtg atactaccga tagcattttt
    15241 ttgcttataa aataattata agtatttaga gatttttctt ctaacattct tcaaacaaga
    15301 aaaatcacaa aggttattgt tatttttata tattcttttt aagaatgatt gtttttttat
    15361 agaaatttta aaaaataaaa cacgttattg atggatagtt agtttgttat ttggtaatat
    15421 tatagaagtt gactggtagt gatttatttt tcgtcgtttt ataaaaatgt tattttttgg
    15481 aaaaattcac aaatatgtaa cgaatgtttt tctggaattt gctgtgttaa aaagcagtat
    15541 gactaatata aatactattg tcatttatgc aattttttat ggatagtaat tttagagggg
    15601 aatcaatgaa ggaagaatag aagggaaaaa tagttgcaaa tacgccagtt agcaaaaata
    15661 gcaatacatc ttcaagcttt aaaattcgag agaatcatct tggtagtgga atcaactaca
    15721 acaaaaggat taaaccaatt aatagataga attaccaatg gaaaaataga aaaggtagtt
    15781 attctataca aaagttgttt aattcgcttc ggttatgaac ttagtgaaac cctttgcaat
    15841 atatggtaca gaatatagaa attattgaca ttacagaaaa tgatgaagat ttaatacaga
    15901 ttgtcactat ttgtagatac cttttacaag gaaaccgagc caataaagct aagaagatga
    15961 ttaaggagtt gatggaagac gatacaagtt aagaaagtga aactacgccc aaataaagag
    16021 caaaaagagt aattggacgt ggaaaatgca agaaatgaac catcgattcg gtggacagtt
    16081 tattagtaat gacggtttga gaacatccat gacgagaatg aaggaacatc ctaaatgcgt
    16141 ttagttgaac caagtgccaa ataatatggc caaataagcg atcagttatc gatgaatccc
    16201 aagtattcta aactatatat tcattttgat gctaagcatt gatatatttt tttgggattg
    16261 atgaaggtta accaatacag ggactcactg atgaaattct agagtctgac cttggtatca
    16321 acgatttagt gattgtttct aatggaaaag tataaaagta tataagtaca ttaacaaaat
    16381 aactattagg gttacgctcc agcttgtgca aggcactggc aggaggaatc gtgaaatcat
    16441 aattatggtt aagccacacg gacaactaaa agtcatacaa agctatcgaa tcaatcaaca
    16501 gaagacaatc ggcaatcatt agctttgttt acagcttaca ttgcaacgct tgagttgaac
    16561 cgaaaatacg agggaggtaa cgcagccatt ttgagttggg gaatcttttt agaaaattat
    16621 cgggtacctt gttgtttagt caaaattata agggggagta atagtgagga acaaatttca
    16681 taaactgtta agtatgtttc tagttatgct tattgtgatc aatcaatttg ggaacataac
    16741 ggttctagct gagtctttag cagaacagcc agagcgttcg ctgacgatcg aagttgatca
    16801 agaggaggct gctttgggtg agcagttcca gttgcgagtc agaggaacac cagacctgct
    16861 aaatgcattg gtcattgata agagtgagga tttgattgaa ggggaagtga agcaactcaa
    16921 tgattacgaa cgtctgatta cttattcttc ccagcattca ggtaaatacg aattgaccgc
    16981 aagaagcggt gatattcaat caaatacggt ctcaatagaa atcagtgtac cagaagaaag
    17041 cacaagtgag tcttttaatg taccagaaga aagcacaagt gaatctttta atataccaga
    17101 agaaagctta agtgaatctt ttaatgaagc cagatcatct gagccatcta taacgcagga
    17161 atctcagatt gaaagacaag aggagctctt gaattatgac atcggcatct ctgctgagcg
    17221 ccccactttg ccgagcaggc atacacaaac gttaaaggga tacattcaag gaggcgctgg
    17281 cgatattctt gaagaatatg gggagatggt cgtacgagtt cctagagcat cgattggctt
    17341 aattgagttc attagagtgg aggtcgctga tgattcacct ttaaagccac tggcatttta
    17401 ccaagaaggc acagacgttg tttttccatt tacctttgat tatgaaggat taaatgaagc
    17461 cgctcagtcg tatacattca gtatcacgtt tgaagttgct ttctttcaat caggcggtac
    17521 tgagccaaat aatgactttc aagtgagtct tacttatgct gagcgagcag caaacacgga
    17581 attttcaatt acgcctattc cttcatcaag acccattttt tcgaaattat actatggctc
    17641 tagagaaatc gacagccaag gaaatcttgg gaatctgctg attgacgggc aagacgtgac
    17701 caacagtaat aaatttattt tgcaggtaaa ttatgaagga tcacgaaaag acggtgtagt
    17761 ggttaccgat gtactaccgc aaggaacaac tttggcaccg aatccgacta catggagttc
    17821 cactggaaat agagaaccta tttcaggtgg ggttcggatc gcagaagtaa cgaatccagg
    17881 tgaagcaaac gttagaactc attatgtttc cgaggaattt gtggacaaag tatcttttaa
    17941 taaggaaacg aatacacttg ttgtggactt tggtaatcta gcagagggtc aatcgtattt
    18001 tattgaatat gctcttgaag tgaccgatgt cgacttgttc aatgaaggaa gacaagagga
    18061 tgggttttct cggaatcgag cgagtatgac ctacaataat caggtaatga gccgagacta
    18121 ccgcttgaga atccctgaaa gtaatcttcc ggcaatctct ttaagaaaaa gtgtggacaa
    18181 aaatgttatc aatctcaatg aaaatgaact aacgtatact ctgcatgtct cgatgttttc
    18241 tggaacaaga aatacgcttg ttattgaaga tgttttggaa gaaggcatgg aatttgtgtc
    18301 atttctatca gatattccct ctttcattga tgccgaagtc aataatggaa tagttcgttt
    18361 cagtgcgaat aatacgattg gtggtccgac aagttttacc ctctctttta aggtcaatgt
    18421 agaggcgtat gcggtcggcg atcaaatttt aaactttgca acgcttgtga atagtgacaa
    18481 tcgattgaat acgagtactg taagaacaag gaaaatcgat gggcgtatta aagtaattaa
    18541 aactgatgag aatggccaaa ggctggcagg agcaaaattt gaaattttat caagcgattc
    18601 acaagtgata caagaaggta taacggcaga aaacggagaa tttttaagtg aaccgcttcc
    18661 tgtaggtagc tatcaagtcc gagaaacaga agcaccggaa gggtatcttt tagatgcgac
    18721 ggtacatgat gtttttataa atgaatactc catagaagaa gtgacgttaa ccattgaaaa
    18781 catccttgat acgggtggtg ttgaactaat taaacatgct gaaggcagtg gtgaagtcct
//
LOCUS       DAFEKH010000055        17438 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.058, whole genome shotgun sequence.
ACCESSION   DAFEKH010000055
VERSION     DAFEKH010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17438
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.058"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            282..521
                     /locus_tag="LP386_002212"
     CDS             282..521
                     /locus_tag="LP386_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919424.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(883..1143)
                     /locus_tag="LP386_002213"
     CDS             complement(883..1143)
                     /locus_tag="LP386_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919425.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(1328..1825)
                     /locus_tag="LP386_002214"
     CDS             complement(1328..1825)
                     /locus_tag="LP386_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HBL1919426.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            complement(1955..2665)
                     /gene="budA"
                     /locus_tag="LP386_002215"
     CDS             complement(1955..2665)
                     /gene="budA"
                     /locus_tag="LP386_002215"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HBL1919427.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(2678..4342)
                     /gene="alsS"
                     /locus_tag="LP386_002216"
     CDS             complement(2678..4342)
                     /gene="alsS"
                     /locus_tag="LP386_002216"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HBL1919428.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(4547..5209)
                     /locus_tag="LP386_002217"
     CDS             complement(4547..5209)
                     /locus_tag="LP386_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBL1919429.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            complement(5219..6034)
                     /locus_tag="LP386_002218"
     CDS             complement(5219..6034)
                     /locus_tag="LP386_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL1919430.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(6296..6739)
                     /locus_tag="LP386_002219"
     CDS             complement(6296..6739)
                     /locus_tag="LP386_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HBL1919431.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(6873..7211)
                     /locus_tag="LP386_002220"
     CDS             complement(6873..7211)
                     /locus_tag="LP386_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL1919432.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(7199..7576)
                     /locus_tag="LP386_002221"
     CDS             complement(7199..7576)
                     /locus_tag="LP386_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBL1919433.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKEIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            7800..8993
                     /locus_tag="LP386_002222"
     CDS             7800..8993
                     /locus_tag="LP386_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL1919434.1"
                     /translation="MTTYQRKVLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(9159..9581)
                     /locus_tag="LP386_002223"
     CDS             complement(9159..9581)
                     /locus_tag="LP386_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1919435.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            9976..10170
                     /locus_tag="LP386_002224"
     CDS             9976..10170
                     /locus_tag="LP386_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919436.1"
                     /translation="MVAGSLLSGCGATTSTTQSTSSDQASSSSTTISESTADSSKEQE
                     QIEKKKEEKQKAEKAALEKK"
     gene            10167..10661
                     /locus_tag="LP386_002225"
     CDS             10167..10661
                     /locus_tag="LP386_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919437.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQEAIAQQQAEQARQQSA
                     AEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSK
                     CYGN"
     gene            complement(10823..11995)
                     /locus_tag="LP386_002226"
     CDS             complement(10823..11995)
                     /locus_tag="LP386_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL1919438.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(12201..13016)
                     /locus_tag="LP386_002227"
     CDS             complement(12201..13016)
                     /locus_tag="LP386_002227"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBL1919439.1"
                     /translation="MTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVE
                     TKAPDGYQLTNPQKETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNTI
                     TVENVQNYGDFHFIKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWS
                     DEVTGSDWEEVKLISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDD
                     DPTTSDETTIDNQPKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            complement(13166..13612)
                     /locus_tag="LP386_002228"
     CDS             complement(13166..13612)
                     /locus_tag="LP386_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HBL1919440.1"
                     /translation="MKNIKTKIWTFLGTAIMLLPFVLGLGTAEVSAAVSPTPENVTVN
                     LHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKDTAVPADATPFA
                     SVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLP"
     gene            complement(13609..14613)
                     /locus_tag="LP386_002229"
     CDS             complement(13609..14613)
                     /locus_tag="LP386_002229"
                     /inference="COORDINATES: protein
                     motif:HMM:NF037639.1,HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBL1919441.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKIKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            complement(14653..14982)
                     /locus_tag="LP386_002230"
     CDS             complement(14653..14982)
                     /locus_tag="LP386_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HBL1919442.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     TEIKTSD"
     gene            complement(15108..17435)
                     /locus_tag="LP386_002231"
     CDS             complement(15108..17435)
                     /locus_tag="LP386_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBL1919443.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSAIETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
BASE COUNT         5035 a         3467 c         3043 g         5893 t
ORIGIN      
        1 tatcctccta gcaactattt aaatacccaa aaaaattacc tctagataat atcataccta
       61 cgttttcact tataaatttt ttcataaaaa aagcgtttag aggcataatc gttaatacag
      121 atggtaacca atgtatctgg tttgaactgg gatatcaccc tctccatata tgtattacta
      181 agactaatag atactataaa agacttgata gttttgcatt gattttgcct aatactgagc
      241 ataggtgtat gctaaacgat actataagga gtgtgtacat aatgaaaaga attctgttta
      301 tcagtttatc aaatttattg ttacttactg cttgtgggac ttctgcatca aagaacatac
      361 cttcagatac gcaaatttcg aatagtatcg attcaacaat ttctacaaat gagaaaaatt
      421 ctccggtaga aacttccgat ataaaagttt ctacctctgc aaaaaacagg gtaaagaaac
      481 tgtcagcacg tctcctttat ttcaaacaaa ctctgaatta gcttcttcat cttcttcagc
      541 aaataatgat gatagtttcg cgtttactcc taactaaatg caacctttac aaatgcttta
      601 cgataacaag cctgagctaa atgatcctga tatcagtttt gcattttttg aaatgattgg
      661 atcggatgat ctttttaaaa ctactagttt gtctatccga aaataggaca gttctggcag
      721 tataggtttt tatcgagttt ctccaccagg cctcgttaca gagacagatt ctctaggcga
      781 accttttgaa taaatcaaaa atcatgaaca atcactgcca actaaataaa gtgccttcaa
      841 aagcttggtc ttctcgcttt tgaaggcact ttatttaaat ctttatgaaa ctaaagtatg
      901 ttcatatttg ttgctatagt tatatagata ttctgttgtt tccaactcat aaacgtgagt
      961 atattttgcc actacttttc cgcatttttc taatatttca ttgcgatcga cgtcatgata
     1021 ttcgtctacg cagatcacaa cacaattttc taatttactg attacttctc caaccacttt
     1081 ttgtttcaag ccaataggtt ggcaaatata tttttttcct aaaatgatag tttcgttatt
     1141 catatttcat ccatccttaa tgtttttcca ttatttaaaa tgataatacc attaaaatat
     1201 gattatgaaa atcaataaca cttgtgattt tataaaaaaa taaaaaaacc gaaaaacaga
     1261 aatgcccact gtctttccgg ctctttttat tcttgatttc tcttcttttt tgtttcaata
     1321 gacgatttta gttattaata aatgaaaaag catttatatt aaaatttgct aataaaagat
     1381 ctacatattt ttctagaaat gcttgatcga tttcatcata ccctttcgtt actccgcaat
     1441 cgatatctaa aacaccgatt aaattacctt cttttaccat tggcactacg atttctgatt
     1501 gtgcggctga atcgcaggaa atgtaatttg catgggtttt gacatcatca acgatcaatg
     1561 tttcttgttt ttcagctgat tctccacaaa ctccttttcc catcttgata cgtgtgcaag
     1621 aaactcgccc ttggaacggt cctaaaatca attcattacc atcgaataaa taatatcctg
     1681 caaagacagt ctcaggcaaa gtctcattca acaatgcaga tgaatttgct aaatttgcta
     1741 accagttatc ttctgcttct aataatcctt gttgctgtaa taataaaatt tcgtatgcat
     1801 cttttttctg tttttctgtc cacatgataa aaaccgctcc tttttgatct atggagaaga
     1861 ttatagctca gtttttttgt aaacgctagg tttcctcctc aaaaaaacga gatacgtcag
     1921 gttaatcacc ttgaacgcat ctcgctgtct ttttctattc tgcttgttgg atttctgctg
     1981 ctaaatcagc ataatcaatc gtttcgtgaa caaaagtcgg atcatcaact ggaaaatgct
     2041 gtacaaggga cgagatgcgg ctaatctcaa cttttccttc agccacttca aaatccatta
     2101 catgtccgcc aaatgtatgt gtatcatcga taaaatgcaa gtgaaatccc gctgcagcaa
     2161 ctccttggaa taattcaggc gtaaagaacc cgactaatgt tccttggaca ttgctttgtt
     2221 ggaattctgg ttgagactct gaaatttttg ctagtcttct gtaaggtttt tcttgcttcg
     2281 gcatgatacg gatgtgcata tttttgaata atccagttat cttcactgcc aaaaataggt
     2341 tttccccggc ttctcttact aatatgtctt ttttcaattg ttctccatct gcagtttttg
     2401 agacagaaaa actagtatct ggcgtaaaat ctgtaattgc tgcatagggg gtaagttcac
     2461 ttccatctaa ttgggcaact gagccatctg atcttccttg ataagctacg ccatctaaaa
     2521 agatgacttc accatcaagc ccatgcaatg ttcccaatcc cagagttcct ttttctaata
     2581 tatgagcaat cgtttctgtt ccatccatca agccagccat caaagctcct aatgtcccgt
     2641 gctggtataa gattttttca gtcatgtcga cacttcctta atagaattga tctggtaaga
     2701 ttgtttctcc caatttctca ttatcacggt aatcaatcgg aatatcaata attacgggtc
     2761 cttctgtcgc aaatccttct tctaaagctt tttctaattc ctctacactt gtagctcgga
     2821 ttcctttagc gccaaaagct tctgcatatt tcacaaaatc aactggacca aagtctacac
     2881 ctgacgcccg ctgatatttc attttttctt ggaactctac catattgtag tgtccatcat
     2941 tccaaatcaa atgaacgata ttcaattttt tacgtaccgc cgtttctaaa tcctgggcag
     3001 agaataaaaa tcccccatcg ccggaaactg atacgatttg tgtatttgga cgcaccaatg
     3061 cagcagaaat cgcccatggc aatgcaacac caagcgtttg cataccatta ctgaataaca
     3121 aatgacgagg ttcataactt ctaaagtggc gtgccatcca aatataatga ctacctacat
     3181 ctacggtaac agtcatatca tctgttactt ttgactgaag cgtgttaata acttctaaag
     3241 gatgcaagat acctgcttct ccttttgatt gaacaatgtc ccgctccgtt aattctgctt
     3301 gaagagatgc taaatattct tttgcatctt ctgacacttg ttgaggctct aatgaacctg
     3361 tcaataaatc aagagtggct gagatatcac cgatcaattc tctttcaggc tgcataaaag
     3421 gatcgatttc agctggcgct tcatcgatca caatgatccg cgcatctttt tccgcattcc
     3481 agtttcttgc ttcatattcg attggatcat agccaatagc aataactaga tcacttcgtt
     3541 tcaaaagcat atctcctggt tggtttctaa ataaacccac acgaccaaag aaatgcgctt
     3601 ctaattcacg tgagatcact ccagctgctt ggaatgtctc tacaacaggc aatgctgtct
     3661 ttccaactaa ttgcctgatg gctaacgttt ctttttcact tgatcctcgc atacctacta
     3721 atagtaccgg tagttttgct tctctaatgc gttcagctag gtaacggata tcatctgcag
     3781 aagcagaacc taatttagga tcgctcaatg gcttgatgac attcccttgg acaggtgcat
     3841 ccactacatc ttgcgggata ctgataaagc tcgcgccttt ttttgaactc ttagccatac
     3901 gataagcatt ggcaatcact tctgaaattg tttctggatc ttggatttct gcactgtatt
     3961 ttgtgattgg ctggaacagt gctgcattat ccatgctttg atgggtcaac ttcaatagat
     4021 cgcttcgttt tacttgtccg gcaattgcta aaactgggtc accttctgct gtcgctgtta
     4081 ccaaacctgt agctaagtta ctagcaccag gaccacttgt tgcgataact actcctggct
     4141 ctcctgtaat acgtccgatt gcttgtgcca taaatgcagc attttgttcg tgacgagtca
     4201 cgattaattc aggaccttga tcctctaatt cattaaatac accatcgatt tttgcacctg
     4261 gtataccgaa tacataatca acatgatgat taatcaaact ttctactaca gatttcgaac
     4321 cttgtttcat tttttcgtcc attgaacatc gtccttttta tgctttattt ttaattatta
     4381 gttagaaata atcacaaata attgatacag tttctaaacc tgtttcattc aaaagtatag
     4441 cacgttttat ttcatttgtt tagccatatg tttcaaaaaa tgaaaaagaa tgacagtttt
     4501 tacataaaaa ctgtcattct taattgaaag tttcaattta taaagtctac agatccatag
     4561 ttctcatcaa tttacgattg ttgaagtaaa tcaaaccaaa tacgatagaa ggacctagta
     4621 gaatacacca ttggggcttt acgaaaaaga agagaaacaa acttgtcaat agtaaaaaat
     4681 ctagtaaact cacataccat tttttcaacg tatagtagaa cgctatccgt agaacttgat
     4741 ttggtttcga cgctggattt ctcacctgaa aataccagta gttgatgcta aaggaaactg
     4801 ataaacaagc aagtaaaaca aacaacggaa tcaaccattt tccataagaa aaacgtataa
     4861 aaaagaaaca atcaaaaatc attatcacac taactatcca agcaaatagc caataaaaaa
     4921 atccctttag ccaaaattgg cgaaacgtct ttatgaacaa acgtactggt gaaaaacttt
     4981 tttcttttgc taattcttct gtcataccta tcatcacgat gcaacctgga ccaataaaaa
     5041 gtaaagaaaa aataaaggaa aagacattcc ttccatctat cgacaaaagg aacgcagctg
     5101 ctatatacaa gatattgaca caccaaaaac aaaggctact tgccaatgat tgatacaacc
     5161 aataaaagaa ttccatataa acatttttgt caaaacgctg ctctttcata atcacctcct
     5221 attccttcat tcctgatgaa gcgatccctt ctacaaaata tttttgcatc gctaaaaata
     5281 taaaagcaac aggaagaaca gaaacaactg aggcagccat gattaatgcg tactctgcat
     5341 caaatagccc aataaacatt ttcaacccta actggattgt tttattttcc gtagaagaca
     5401 aataaatgaa tggccccata taatcgttcc atgtattaac gaatgtgatg atcgtcaaac
     5461 tggcaatcgc cggttttgta agaggtaaaa tgatcttgcg atagattccc cactctgata
     5521 agccatcgat ccgcgcactc tcacataaag aatctgggat actactgtag tattgcttca
     5581 acaagaacac accaaaagca ttgaacgctt gtaatagcac caacgaccac aacgtatatg
     5641 ttaaacccac ttttctcatc ataatgaact gcgggatcat ataagactgc caagggacag
     5701 caatcgtgcc gatatatgct aaaaataaaa tatcgcgccc tttaaaattt agtttagaaa
     5761 acccgtaagc agcaaaacta gaagtaaaca actgaatcaa cgtgatcaca acgcttaaaa
     5821 aagctgtatt cttaaaaaat gtcactaaag gaatacgaga ccaaataacc agataattct
     5881 ctaaatgcca agttttaggg atccattgaa tcggaatcgt gaacacttca ttatttgctt
     5941 tgaatgaagc agaaaccatc cataaaaaag gaatgatcgt caataaagct aatacaatca
     6001 gcagaatcat acccaaccat tgaataaagg gcatgttttt tgaacgaatt tttgcttttt
     6061 ttctttcatt tcgaacacct ccaaagttat aatcttcatt tctttgtaat gattacaatc
     6121 cagaacaacg gttattatag ctgattcatt tccgttcttc ttatgtttgt aagcgcttat
     6181 ttaacaagtt atgtaaatct ctttattttt tttgatttaa aaatgaaaaa atacaaaagc
     6241 aagactgtca tacgtctcgc ttttgtattg aaatttcttc gattagagat acttattact
     6301 gttcaaaagc ttctttgaaa cggtgaatca attcattgac tacaggtgat aaaatccgat
     6361 tctttttcca gactagcatg cagttcgttt caatcattgg gtcaagcgga acgaatgtca
     6421 ctcgctttga aagatgactt acagcacctt ctatgactaa agcagcacct acctgattct
     6481 caattagcgc aaatacattg aaaatcaaat tgtacgttcc tgtgatcagc aactgctcct
     6541 tttttatgcc taaccagtca gcaaacattc gctgtatttc tggacgcttt gagatcaaaa
     6601 gaggtacatt cgcaaagtct tcttttgtta tcacgtcttt ttttgctaaa acagaatttt
     6661 ctaaaatgag caatccccat ttttcctttc ttggtaacaa aatcgtttcg tatttctctg
     6721 tatctactgg atctagcaaa atcgctaaat ctaacaggct tttttctagt cactccgtga
     6781 tatcatcact tgttccgctg tggatatgaa attgaacgct gggataatca cggatcaact
     6841 tttctagtaa tagtgccaat gtattcgaat tatcagcttc cacacagccg atcgtaaatc
     6901 ggccgctgaa taattgtttt tttctgttct cgaattcttg agtggtttga ttcgttaaat
     6961 ctaaaatttc ttctgctcgg cttttttaga aaataacctg cttctgtcaa gatcattttg
     7021 cggttttcgc gtacaaacag ttctgttcct agttcctctt ctaactcctt cagttgtcgg
     7081 cttaaggttg gttgtgtaag atgtagaact tctgcggctt gagagattgt tccttcttct
     7141 gcaattgtcc aaaaatattt tagtaagcgt aactccatag cgatgctcct tgattttttt
     7201 acttgataca ttccatttta tttctagata acacacgatc atatttcttg atttttcctt
     7261 gtaaacgttc caaacactct tgcatttcag caatttcttt cgtcaaaagt tcactttctt
     7321 caatcaaaag cttacgccgc tcaaatacag ttgcttctcc ttcgctagat aggcgaatat
     7381 attcaatcaa agactcgatc gataatccgg catttcgcat acagatcgta aagtcgaccc
     7441 attttaggtc ttcttctgta taatcacgga ttccgccttt tgtccgatta actggtggaa
     7501 tcaacccgat tcgttcataa tagcgcaatg tatcggccga aatgcccttt tcttcactga
     7561 cttgtttgat attcatctga tcactctttc tcttaatttc ttgccacttt acttatgtat
     7621 tttatttatt ctacaacttt aagtgtactc caagtcaata ctcatttcta ttaaaactaa
     7681 gctggattat ctatatcggt tgtttgtgta ttatttcaaa taaaaaagtc ttgttttttt
     7741 attctttttt ggatatactt ttaacaattt agggaaattt taggaaaagg ggtataaaaa
     7801 tgacaacgta tcagcgaaag gtattattat cgacatcggc gggaattgct ttagagaata
     7861 tggatattat gtttttagct ttttcattat cttcaatgat tacttctttt catattagtg
     7921 gtacgcaagc gggtttcatt tcaacgatca ctaatttggg gatgctcatt ggaggtattt
     7981 tttttggcat catagctgat aaatatggac gtgtgaaagt attttctcaa acggtccttc
     8041 tgttttcgat tgcttcttta ttgatgtatt ttgcttcaaa catctacttg gtttatctct
     8101 ttcgctttat cgcaggtgta ggagcgggag gagaatacgg ggcgtgtatg tccttgattt
     8161 ccgaaagttt ttcaaaaaaa caaattggac gagcttcttc ggttgctggt attggtgcgc
     8221 aggtcggtgc ggctttggct gcgattttag ctgctgtgat cattccaacg tttggttgga
     8281 agatgttgta tgtcgtaggt gtactgccgg tgttgatggt cttgttcatt cgtcgcggct
     8341 tgactgaacc aaaggaattc aaatctgtac aatctgccga aaagaaaacc aaacttagca
     8401 gactgtttga atcaaaacat cttgcttggc aaacatgtgg ccttagtatc atggtaactg
     8461 tccaaattgc cggctatttt gggttaatga attggctgcc ttcaattatg caaaatcgat
     8521 tagggctttc ggtttctggg tcttcattgt ggatggtcag tactatttta ggcatgtctt
     8581 tggggatgat gacttttggc ataatcatgg ataaattggg gcctaaacta gccttttctt
     8641 tgtttttaat ttgttcatcc ttatctgtct atctacttgt gttagcccat agccagtgga
     8701 gtttggtagc agccgctgtg atagtcggct actttatcaa tggcatgtat ggtggatatg
     8761 gcgcagtgat tagtagtttg tatccaacag aaatccgcgc gacggcgaat aatttcatta
     8821 tgaaccttgg acgagctgtt ggtggttttt cttctatcgt catcggtttc ttgatggatc
     8881 attatagttt aactgccgta atcttgtttt tgagcggtat ttacctagtc agtctgctgg
     8941 tcttgacaac tcttactggt gttacagcat taagggaaag cttgcagcat tgatagttga
     9001 gtctgtaaat gacaagaaag aggtgtggca aaagcttgca tctgcggtaa taagaccagc
     9061 caaatcaaaa acatgagaca ctgtttccgt ttggctggtc gtattacttg atgcagggca
     9121 gctttttcaa ctgctaattt ccttctatct ggcggcgact attctttgac gtccgtcatt
     9181 tcaaagtact ttactaataa cttagcataa cgaaaaactg tggatacact cgtatattga
     9241 gcgtctgcat aatcttccaa atttttctca ggatgttgat acatgaattc aatcaaatga
     9301 taattatatg attttctgta gaaatgaaga taaataatgt agattgggaa gttctcctgc
     9361 ttttccatag aaaagcgccg attattctca ttcttcaaaa tgaccttatc aggatatttt
     9421 tggaacaatt cttctaaatc tgttagataa ttcaagatag acttacttga taccttcaat
     9481 tcgttttgta gttcttctat tgaacaccaa cgttctgttt caagcagtaa atgaatcatt
     9541 ttaattttct tttgagaaac ttttgttaaa aaagtctgca tattttctcc tcctgtatct
     9601 actttactat actacataca agaaaaaaaa cggatacaaa tatcatattg tcacaccgtc
     9661 aatagtgcat aaacctgtta ttatttctct ttttttccta agtattctat tgatatgaat
     9721 catttaatcg tttattatat aaatgtcaat aatctaataa taaaataacg tacatatttt
     9781 attattgcat acttaataac agaactatag caaaaaatcc cgtgtatcaa cacgggatta
     9841 gattaagttt cctcaatcac tattcataac acaattatta taacaagtaa gtaaacaatt
     9901 gaaaaggaca tttattgaaa acggttgttt tttacttaag gaggaaattt agcgaaaaaa
     9961 ttagttgcat tgtttttggt cgcaggaagt ttgttgagtg ggtgtggtgc tactacgtct
    10021 actactcaaa gcacaagttc agatcaggct tccagcagca gtaccacgat ctccgaaagt
    10081 acggcagatt catcgaaaga acaagaacaa attgaaaaga aaaaagaaga gaaacaaaaa
    10141 gcggaaaaag ctgcactaga aaaaaagtga cagaagcgga atctgctttg tcacaagctg
    10201 aagcaaatcc tacaaaagaa aactatgcaa ctgcttcagc agctatccaa gcgctacctg
    10261 aaaacaaaca agagttgaca agccgtcttg ctgcaattga ttccacaatc aaagcaaaag
    10321 aagcagaaga agaacggaaa aagcaagaag aaattgcacg acaacaagca gaacaagcgc
    10381 aacaagaagc aatcgcacag caacaagcag aacaggcgag gcaagaagca atcgcacagc
    10441 aacaagcaga acaggcgcga cagcaatcag cagctgaaca ggcctctcag caggcacaag
    10501 ccgcagctcc tgagcaaaat aatgaacaaa ctgtctatgt cacaccgacc ggttcaaaat
    10561 accatacaca taaatgtgga aatggtacgt atacccctgc cactttaagc gaagctcaag
    10621 ctcgtggttt aaccccttgc tccaaatgtt atggaaacta attcaaaagt tatactataa
    10681 taataaaatt cttctgaaac ataaaaaaat agaagatggc gttccagata gtaaaccaaa
    10741 aataacagtt tacacgtcca tttcgtcagc ttctctcttt tttcatttag tctgttccct
    10801 ctgctttttt ggacatcttc attcattctt tctcaatcaa atagtacacc tctttttctt
    10861 ttcgcagttt atatcttcct tttttcaatt tcattgaaaa ctgtttcgaa tgtttatgtt
    10921 ttacatggat tttaagcagg agctcctcat gttgcaagcg atagttcctg ccttttaaat
    10981 cagaaaatct cactagtccg tattcatcag aagctttcac aaatggaact ttttctctag
    11041 taatatagtg tttgccgttg agcgttttta cagaaaagac cattccttcg attggtcgtc
    11101 cgtttgtgtt ctttacataa aaagataaag gatagtttcg cttagcgatg gccaaagaat
    11161 ctaaataagc gatgagtagc caaactaagc cgattgatcc aagtagtata ccgataaacc
    11221 aaataaaaaa tttccatttt ttccattgat caattccttg gatcgctttt tttgcctctt
    11281 ttgcttgata aggaatacga tgccccgtca caagcagtcg atgtgtattg accatataag
    11341 gagtacaggt aagcaaagtc acgagatctc tgcctttttg gatacccaaa gaatctactt
    11401 catcaggtaa gaccacttgg attttttcta cttgatacgc caatgtcttt ccattgatct
    11461 ggatgaaaaa ctggtctcct tttttcaact taggcaaatc tgtaaataat tttgcttctg
    11521 ggagtccacg atgcccagaa agaacggcat gggtgttttt cccgccagtc ggataagaac
    11581 tttcttccaa taatgacgtt cctttttgca aaaatatttc cgttgtctga tcgaatatag
    11641 gtaagctgac attgattttt gggatttcga tgactccaag catatgttcc ataaaaaagg
    11701 cattactagg taaatctttt aatgcttttg catcaactgc ttggttgaaa ctgcctatcc
    11761 ctggtgatac gttttgctct gccaactgtt ggtttttctt tgtcattttt tcctgctgtt
    11821 tttttatttc ctctgaattc ttattcgatg cttgcttttg ataatggatg atcatttgct
    11881 gggcaagaaa atcattcagt gaatcttcta caaaaggata agaaaagatc ccgatcccaa
    11941 cgactaaaat gattgccatg aagatgtcca gtattcttat tctgctttta ttcatcatgt
    12001 ccacctattt tctaatatgt atatgaagag gttgtgaaat cagcgccttg acctgagtat
    12061 tagcgaagca aacggcaaaa tagttcctcc tattttgccg tttgttgagc gaataccaag
    12121 agaccgacca cttgtcacaa cctttctccc catttgaatc actatcgttt atttatcgta
    12181 tgatttttgt ttccaatagt ttaagcttct gtttcttgat ggcgtttttt gaaatagatc
    12241 actgctcctc caactaaagc agtacctacc aagatgaata cgatgatccc cataccacca
    12301 gttgaaggca agattccttt aggttggtta tcgatcgttg tttcatcaga agttgttgga
    12361 tcatcatcta ctgtaaattc agtgtacgca gcttcattct taggtaatgc gtagccttct
    12421 ggtgcttttg tttcttgaag gcagtatgcc ccttgtttca gcccttcgat tgaaaatttc
    12481 ccttctgaat cagaaatcaa tttcacttct tcccagtcag aacctgtgac ttcatctgac
    12541 caagcatatg ggtattctcc tgaggcaagg tttgctattt ttttcattaa tttaacagtt
    12601 ggatcttttg ctcttagaat agaaaattct gcatcggcta atttttcttg cgtgttcaca
    12661 tcttgtttga tgaagtggaa atcaccgtag ttttggacat tttctacagt aatcgtgtta
    12721 tccgtagttg tattttcccg attgactaca ccgtttggat tcccaagatt ggcttcatct
    12781 gcgccatgga tgataccggt tgtttgttgc aattttccgt tttttactat aaaagtagtt
    12841 tctttttgtg gattggttaa ttgataacca tctggtgctt ttgtttcaac taaagtataa
    12901 ttgccgtcta ttaatccatt gacactgatg gatccttcag tatcagttgt gaatgtcaac
    12961 gctgactcag caggatcata gagagcgaca ccagtgtttt catcaaaacc ggtcacgaat
    13021 tgattctctg aatttttgat ctggaattgc gcccctgcta acttatctac ccctgaaaag
    13081 ttcccagctt tctggatttt gatattgctt tctttgatga catttttagc atataggtga
    13141 atcgtgtcta aaggtttgtc agggtctagg gtaagcttaa cacgatattt ggcgacgttt
    13201 cgacaccggg ctttggtgtt tctacaaaga cgtatacagc atctttccca tcagatttac
    13261 ctggaagagt caggttagct aatccttcac cagaagtcgt tacacttgcg aagggtgtag
    13321 cgtctgctgg aactgctgtg tctttacttg gatagtacgt agcagtgatg tcatatacgt
    13381 tgaattcaac gccgttcaac ggttcgctat tcggaaatgt caattccgtt ccgttgttta
    13441 tttgattttc tggtgctgaa gtgaatttca atttatgcaa attaaccgta acattttctg
    13501 gtgtaggtga tacggctgca gaaacctctg cagttcctag gccgagaacg aaaggaagca
    13561 gcatgatagc agttcctaaa aacgtccata tttttgtttt gatgtttttc attttatttc
    13621 cctcctattg tttccttttt gttgtttttt ataaaaccaa gctgtccctg ttgaaaggac
    13681 tagcaataac cctaaaattg agaaacctcc aagcatctct tcgcttgttt ttggaaagct
    13741 tcctccattt ttttcatttg atggaccatt tgtctgcatc tgaactggcg tttttccatt
    13801 attcgtcgga tttgcttttg gttcgttgat gatttccaat ggtataggat gaagcggatc
    13861 ataactgcct ttttcaactt caaagagaat ggttgattga ctcaatatat atcctttagg
    13921 cggtttaatc tccactagtt cgtaacttcc aaaagacaat ccatggacag aaaatgttcc
    13981 atctttactg gaagtaaaaa tcgttgctct tgaatcatct ttggctaccc aatgatttat
    14041 cccgttttct tgcgctaagt attggtcatt ttttttgact agaaattgag catctgctag
    14101 tttttgtttc gtttgccgat ccactttgac aaattgtttg cctcctgttt ggatggcaag
    14161 atgtgtttct actgtttgat tgtcagtcgt caaacgtaca tcgttatcaa atgtcgtttt
    14221 ttcactgttt tctttcaatg tcatttggta acggatcgtt aatttttttc cagcaaacga
    14281 actaagatct tttccagaat ctgataagac aaaaccatgt tttatttttt gtgtgtgaaa
    14341 tgtatgaatc ttgtctccac caatcaaaaa atcgatcgtt tctggttcta gccataactg
    14401 aggatcagct gtatctttga tcgtataggt tcctatctcg ttgatgttct caggaattgt
    14461 tacggtgatg agataaggga ctttatcccc atctgcaaaa tctgtctgct tattctctac
    14521 tgtttttgtt aatgtgagtg cagcaggtat tttttgttcg ctctttggat acaagtggat
    14581 ggtcgtcaat ttatgattag atgaatctgt cacaggaagc acaacgacaa atggtgctga
    14641 tttttctttt acttaatctg aagtctttat ttccgtaaat cggtaaacag cgtcacgacc
    14701 ttgctcatct ttgtccgatg cactaaaaga agcaatgccc tcttcctcgt ctactgtttt
    14761 tgtcacattt tctgccagta ttttttcact atcacttttt tgtgctagtt ttctttgtgc
    14821 gtcttccaca ctacttcctt ctgaccgcag cttgtaaaat tcatccgaga catcatatat
    14881 agcgaaagta acgccgttca acccttttac tccttgaaag ttatccggga tatttattcc
    14941 gtcgttttga ctgatacttg gcatcttatc gctttcgaac attcgattat gcaaagtaaa
    15001 tgtaataggt gattctctag ctgacacagt cggagaacct ataaaaaaga ccagtaggat
    15061 aaaaaagaga acagcaaata tatccacacg tacatttttt gtttttttca tcgctgttca
    15121 cctgcttttt tcttacgatg gataaaataa aagaagccag aaaaaataaa gatcagtcct
    15181 aaaaagacaa agggcagtag acctatccca cctgtcgaag gaagcaagag agtcggattg
    15241 atcgtcaact tagcggtatc tgttgcgata atcgtataat tattgtttac acttccttcg
    15301 cctaaactaa tcgttactat ttgtgatcca atatctgtcc ggctgttaac tgttagggta
    15361 taatccaatg attcgcctaa gacaacaccg gtaacgtgga gatttccaac cgaaatcgag
    15421 tgactttggg catcataatt aaaggcagcg tcatcgacag taatcactgc gttagcttta
    15481 tagatggtat aagttcctga tgtgttggct atatcagtaa atgacaactt gggatttgct
    15541 gctttgactt tgtctattcc gctattcgtt agtttaattg tatagctgcc agcattaacc
    15601 atattttttg ctgattgtgc atctgctgtg taatccatac tgctaagtgc cacttgtact
    15661 ggagtaagcg aactagtgac accctctgct agcttgacat ggattgacgg gacacctgct
    15721 tttccatcat atgtcttact gccactgagc tctaccgcac cgctgatttg cttaatcgta
    15781 tagacatcag atgtctgcac gatagtaaat aaatagtttg ttctggcagc tagtttagct
    15841 agtccgcttt ttgtcaattg ccaagacgta taggttccaa tttcagtagg cgcagttact
    15901 tcaactccct tttcattcat cgctttgaaa tcagttggat tccatgtgat ttgatcaata
    15961 ctgagatcat tgtttaaaag ggatgttgat tctgttttat cattaaaggc atatttaacg
    16021 atcggtacaa cagaaagacc atcatagtac ttactgccat ttgcattgat tgatactgtt
    16081 gcatttgtct tataatatag gatgacttca gaaatctgtt ttccatttgc gtcctttacg
    16141 attacatttc catttgtatc taaactagct aaaacactca ttgctgattg gttctttgtt
    16201 tctatcgctg aaacagctgt aaaggtatat ccgttgatag taggcgtatt agtcgtcagg
    16261 tcttgtgcag cacttccgta agtaagattc attattttag aaggagcaat catctgtcca
    16321 aaatagtctt gatacttaat agtgattggt gtttgtttgc ctgtataggt caccgtatcg
    16381 acgttacttt ctagggctgt gaaagaaccg tttgtttgtg caaaagaata gcccgttact
    16441 gctgttggag tgataaccac tttgtcaccc acatggattc cagataatgt agtcccgtac
    16501 gttccgattt ttgctgctcc accattgact gtataagaaa aagttcctgt ccgattcgca
    16561 ttgacctgaa ccgttgctgc ttgataggtt ggaaaatttg aaacatttcc cttaccatca
    16621 acgatctgcc catttttgat cgagtacccc gtgaatggaa tatcatttgc taactgtata
    16681 ccgattgaaa aagtactcat acctcctccg gcaggaagcc ctccccatgt tgagggtgta
    16741 aaagaataac ttttatccgc attgggtgta actgaatcga tcgtatttcc agcggtagcc
    16801 acccccatat agatactttt tgggaatgtg atagtagtac catttactgt ggagccaata
    16861 aacagattat ggatatctgg acggttatca ataaaagcga ttgctttggt tacgccttgt
    16921 aacgcagttt tatccgcact catcgatccg ttaaccgcaa caatgactcc atctttggca
    16981 tatatcactg tatatccatc tggtatggta tgtccgttga aattcgcagt ggccgcaaca
    17041 gtactaaatg tctggcttct acctgtttct gaataagctt tctcccctgc tgcttttgct
    17101 gctgtgattt ctttttctgt cggatcaatc agttgagtcg aggatgtggt tgaggttgtc
    17161 tcgttgttgc tagactgatt ggtgctttct atggactgta tttcagaata gggtggacta
    17221 tttgtctcct ctgtcgtttg gttagcaaaa tttgacgttt ctgtataaac gtttacataa
    17281 atacttgata agctccctaa gaaagtaaaa atcaagatga tcgaaatcat aatgggatgt
    17341 aagtattttc ttttagatac agctttgagt ctagaaacaa aatgtttttg acatatacgt
    17401 tggattttat tttgagtttt cttaatcatt ttcatccc
//
LOCUS       DAFEKH010000056        17107 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.059, whole genome shotgun sequence.
ACCESSION   DAFEKH010000056
VERSION     DAFEKH010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17107
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.059"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            7..1398
                     /locus_tag="LP386_002232"
     CDS             7..1398
                     /locus_tag="LP386_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBL1919444.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIETSGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            1414..2454
                     /locus_tag="LP386_002233"
     CDS             1414..2454
                     /locus_tag="LP386_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL1919445.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            2473..3558
                     /locus_tag="LP386_002234"
     CDS             2473..3558
                     /locus_tag="LP386_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HBL1919446.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            3591..4553
                     /locus_tag="LP386_002235"
     CDS             3591..4553
                     /locus_tag="LP386_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBL1919447.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSSVEFIRGIDLDQIKHKEFYYKHIDVYQKHDYPRINRNNTTAFKIFR
                     AIINRCLRMIKLPPKIRHHKFDLYHGSQWWALSKECLTELIQMYEQNQQDYLNFKIGM
                     FAPDEKFFHTLFFNSSFKNKNVIGGPDLPLELKNIEETTLQTSKLANIHIIDPSMNKW
                     FDERDIDQIKESEKLFVRKVKSDYSDKLLNRIDKEILKVGNIDE"
     gene            4546..5979
                     /locus_tag="LP386_002236"
     CDS             4546..5979
                     /locus_tag="LP386_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HBL1919448.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQI
                     FYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKGELI"
     gene            5976..7046
                     /locus_tag="LP386_002237"
     CDS             5976..7046
                     /locus_tag="LP386_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919449.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKKIDDYF
                     VYCPELLLYDVKNIKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYG
                     IDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTL
                     LISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLS
                     EEKILLPENWAELRKLVEYGII"
     gene            7033..8454
                     /locus_tag="LP386_002238"
     CDS             7033..8454
                     /locus_tag="LP386_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HBL1919450.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFITIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFSLILHILINQMLIRYVLTS
                     LLIISLVIYFLKIKNRIIDDYNS"
     gene            8467..9474
                     /locus_tag="LP386_002239"
     CDS             8467..9474
                     /locus_tag="LP386_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBL1919451.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            9486..10490
                     /gene="neuB"
                     /locus_tag="LP386_002240"
     CDS             9486..10490
                     /gene="neuB"
                     /locus_tag="LP386_002240"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HBL1919452.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            10487..11635
                     /gene="neuC"
                     /locus_tag="LP386_002241"
     CDS             10487..11635
                     /gene="neuC"
                     /locus_tag="LP386_002241"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HBL1919453.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            11608..12285
                     /locus_tag="LP386_002242"
     CDS             11608..12285
                     /locus_tag="LP386_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBL1919454.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            12275..13417
                     /locus_tag="LP386_002243"
     CDS             12275..13417
                     /locus_tag="LP386_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBL1919455.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            13430..14407
                     /locus_tag="LP386_002244"
     CDS             13430..14407
                     /locus_tag="LP386_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL1919456.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            14407..15315
                     /locus_tag="LP386_002245"
     CDS             14407..15315
                     /locus_tag="LP386_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HBL1919457.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            15316..16068
                     /locus_tag="LP386_002246"
     CDS             15316..16068
                     /locus_tag="LP386_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HBL1919458.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            16073..17020
                     /locus_tag="LP386_002247"
     CDS             16073..17020
                     /locus_tag="LP386_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HBL1919459.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT         6165 a         2190 c         3089 g         5663 t
ORIGIN      
        1 gtatatatga ataaaaatgg agaatggagt gctgcacgac ggatattcat tatattaatg
       61 gatgttattg tatacaatgc agcaatatat agtagtttct tactgaagtt tcgtggagag
      121 atcccattac gaaatttaga aactttccaa cactcagcaa ttattatttc agtgattttt
      181 attgcgttga acattttgtt gggtgcatat gttttttata atcgaatgat cagtgacatc
      241 gtgtttgtca cagtcatcgg tcaggtattg atgacactag ggatcatggt agtgactttt
      301 gcgggccgct ggtttgcttt tccacgtctt gttatcttac tttcatttgt tctcggtacg
      361 cttttcttaa gtatctatcg tattctcgta tataaacttt atttacgcgt aagtcgagat
      421 aaaaaggtcg tcattattgg gttagaaaag gatgtcgcac cagcaatcca aaattttggt
      481 tcaaagaaaa acaacaaaca taaagtcgaa gcagtcattc ttgataacta ttatgcaaac
      541 atcaaaaata tgattaaaga catcgatatt gtctatcttg cttctcatat cgaagaaact
      601 gaaaaaatca aaatctatca attagttact aaaaatgaaa aaaaattgtt tttgaataca
      661 acatttgaaa acttgacatt gatcaatcca aatattatga atttcgaaga tgaaagtatt
      721 attgaaacat ctggatttag aatccaacct gaatatgaac tattcaaacg tttgtttgat
      781 atcatcgttt cacttgtttt attagttatt gcttcaccat ttatgttatt cacagcaatt
      841 ttagtcaaag tgacatcacc gggaccaatc atctataaac aagtgcggat cacaaaaaat
      901 caaaaggaat tttcaatcta taaattccgc tcgatgaccg ccacagccga agcaaaatct
      961 ggaccagttt tagctaagag caatgatgca cgagtaacgc ctgtaggtaa atttattcga
     1021 gctgtccgct ttgatgaatt accacaaatc ttcaatgtgc tgaaaggcga tatgtcgatc
     1081 gtaggaccac gtcctgaacg tcctttcttc gtcgatcagt tcaatgcaga aaacccttat
     1141 tactacttac ggcataatgt tcgtgctggt atcactgggt atgcacaagt ctatggaaaa
     1201 tatgtctctg attacaacag taaattacgt tttgatttac tttatatcaa aaaatattca
     1261 ttgatgcttg atttaaagat cttgctgcaa accatcaaga tcctatttga taaaatgtcc
     1321 tctcaaggac ttgaagaaga cgaaaatgtg atctcattgg cagaaattgc ttttccgaat
     1381 gaaaaaatct ttcgctagtt gggaggcgta aaaatgaaca atccgaaatt cagcataatc
     1441 gtaccagtat acaatgcaga agcaactatt ggtcgaacga ttgatattct aaaagaattg
     1501 gattatgaag agtacgaagt cgttttagta aatgatggat caacagatca aacacaggaa
     1561 atcattcaag aactgattga aaatgatgaa cgttttgaat tgattactac gaccaatcaa
     1621 gggcccggat tagcaagaaa cgaaggaata agacagtcaa aaggagaata tctcttattc
     1681 ttcgatgcag atgacacgcc agtaaaaacg atcttgtcag attatgatca tttgctagaa
     1741 aagagtccaa aagcggatct tgttgttagt tcgtttgttt ttcgtacaat ggacgaggga
     1801 agaatcgttt ccgaaaaaga aaacttagtt acagaatgtc actatctaac tcacgaagag
     1861 tttataaaag acatgtatca gttaatgaat gaacagttga tgtatgttgt atggaacaaa
     1921 tgctatcgta gcgatattct gaaaaataac caaattctat ttaaaactta taatagttgt
     1981 gaggatcgaa tatttaactt acattattat gaatactgtc atcaagtgat catgaaccca
     2041 aaagtagaat atatttatga atttgaaggt gggaagggga tcactaatca ataccgacct
     2101 aacaagttcg aaacatttaa agaattctat tcattagcaa atactgtaac agacgatatt
     2161 aataaagacg gtatggcggc gcttctttta aaagggacaa cttcagttat tttttctatt
     2221 tatagtacct ctgcaagaac ttcaaaagag aagaaagacg aagcaaagca gatattgagt
     2281 gatccagtga tccgagaagc caagcaaatt gctaagacgg attcttcagc aaaaaaaata
     2341 acaaagttgc tttacaatat gccagctcca ctatttttat ctgctgtaaa agttggaagc
     2401 ttcgttgaag tgaaaatgcc agggttaatg gctgctttga agcgagtata ttagttaatg
     2461 gaggaaaata taatgaaaag aattttgcat tttcagggac gaatgggttt aggtggagca
     2521 gagtctttca tgatgaattt atatcgtaaa attgatcgta caaactatca atttgatttt
     2581 ttgatttatg aagattatgc agatgttcaa gactatcatt cagagattga aagattagga
     2641 ggccgtattt ttgttgtacc taatcctaag aaaaatattt ttaaatattt aatagaagtg
     2701 aataagttac taaaaaaaga atctttttct atagttcaca atcaggttta ttttggcggg
     2761 ggaattaatt tatggttagc caaaaagaat ggaatcagac agagaattgc tcatagccat
     2821 gcaactgaag atggaaaatc tcaaaatatt gtaatgaatg tattgcgtaa atttttaacc
     2881 aaattgttgt tacaaaatgc aacagactac cttgccgtta gtcaagaagc tggtgaaagt
     2941 ctgtttcaaa accatccctt tgagatagtt cataatggta ttgatttaga gctttatagt
     3001 aaaaattcag aagctaaggt taataagaga aaagaattgg atatctcaat gagtactttt
     3061 gttgtgggaa acattggacg attagagaaa caaaaaaatc aatcttattt gttagagatt
     3121 tttttagaaa tactaaaaat gaattctgat tcttacttga ttttagtagg tgaagggtca
     3181 cttagaaata aactgaaagc caaagcagta gaattggata tagagaaaag agtaaaattt
     3241 ttaggagaaa gaaacgatat tcccgagtta ttatctgtga tggatgtttt tgtaatgcct
     3301 tctctttatg aaggtctgcc aatggttgga ttagaagcac aagcagcaaa attaaaatta
     3361 gtcttagcag atactatttc caaagataca aagttaacaa ataatgtgga ttttgtatca
     3421 ttagatgaaa caccacaaga atgggcaaaa aaagtaataa aagagccgta tgctaataaa
     3481 ataacacaag aactaaagag ttatgatgtt tcgtacacta ctgaacaaat ggagagtata
     3541 tatagtagag atcattaaaa atgttcaaga tattttagga gtgattattt ttgaaaatat
     3601 gttatttgat attggcatac aatgatattg gcaacttaaa gagattggtc aatcgattga
     3661 acgaaaatgc agtttttatt attcatatag ataaaaaaac tgatatagaa ccatttattg
     3721 aagcatttaa atcatatgat aatgttgaat ttttatgtaa taaaaaccgt gttaaaattt
     3781 attggggtgg tttttccatt gtacaagcag aaatcaattt agtaaagaga gcattacaaa
     3841 atgagaaata tttaaaatat gtattattat ctggtgctga ttatccaatc aaagataatg
     3901 agtatattta taattatttt aaaaagaata gttcagtgga gtttattcgt ggaatagatc
     3961 tagatcaaat taaacataaa gaattttatt ataaacatat agatgtatat caaaaacatg
     4021 attatcctag aattaatagg aataacacaa ctgcatttaa aatttttaga gctataatta
     4081 atcgttgtct gaggatgatt aaacttcccc caaaaattag acaccataaa tttgatttgt
     4141 atcatggttc tcaatggtgg gctttgtcga aagaatgcct aacagaatta atacaaatgt
     4201 atgaacaaaa tcaacaagac tacctgaatt ttaaaatagg tatgtttgcc ccagatgaaa
     4261 aattttttca tacacttttt tttaattcct cgttcaaaaa taaaaatgtt attggaggac
     4321 cagatttacc acttgaattg aaaaatattg aagaaactac tttacaaact tcgaaattag
     4381 caaatattca tattattgat ccttccatga acaaatggtt tgatgaaagg gatatagatc
     4441 aaataaaaga aagtgaaaaa ttatttgtaa gaaaagttaa atcggattac tctgataaac
     4501 tattaaatag aattgataaa gaaattttga aagttggaaa tatagatgaa tagaatagta
     4561 cctgttttag agaagagttt attaagtcga gatgcgtttc gagtaataaa tttaatcatt
     4621 tgtctgcttt attttatgcc tagtactttt aatgtaacta atatcccgat gaaaatagct
     4681 tttgcttggg gtggaattat agttttgtat gaggttttta taaagaaaaa tttttttaaa
     4741 atgcgttttt cttggctact gattggagca atgattagtt ttatcttaac tataatcatt
     4801 aacagagaaa attttttaat tccatctatt tataattttg gatatttgct gattactttg
     4861 atagtaattt ttcctgcaga cttttcacaa agtgaagagg aaaaaaagaa aaaaatggtg
     4921 tattttaata atgttttcat tatcataatt tttttagctg cgctaatatc tatctatcaa
     4981 tttatttttt tgatttctta tcatgtccca acaggaacgc caggattact tgcaagacaa
     5041 ggttttattg aacatcggtt atttggtgtc tatacaagtc caaatgttgg agctatgttt
     5101 ggatatactt ctattatttt aagtttaatt agtgtattaa tttcaaaaat aacaaaaacg
     5161 attcgtgttt tttatatgat gaattttatc gtacaaatat tttatattac actttcttcg
     5221 tctagaggtg cccaggtagt aatttgttct tttttagtat tatttctttt gttgtttgcc
     5281 aattcaaaat ttagaaagag cattagagaa gtactacctg taaaaatcaa atggatggta
     5341 agcatattat tagttctatt ggtatatttt tcttttggta ctaattatgc taaggatttt
     5401 ttagcaacaa ttcctgtatc gattgataga aaagtagaag ttatagagtc aaatgaatca
     5461 gataaaactc cacttccaga aaaagaagta atattacagc attctagtga taactccgaa
     5521 atttcagctg gtcgttttac gatttggaaa gctgcgctta aagttataag accaactttg
     5581 ttatttggtt atggagagac cgatttctat gggaatagcg atgcaaaatt tttgaaaaaa
     5641 gtagatcttg atactacaga tgtgaatgaa ctaaaaagag cacatggaaa catgcataat
     5701 ggatttcttc aagtacttgt atcaagtggt ataattgctt ttatatgtat ctatgctttc
     5761 tatgtgttaa atatctttag tttactcaaa acatttttta gaagtaaagt gaattatgcg
     5821 tttcttggta ttgttttaat ttttatacta tctattttta tagatgaaat ggtggaggct
     5881 catgtacttt tcaataagcg cgatgtcatt tcaattgttt tctggtatta tttgggaagc
     5941 atttcttact tgtatttaaa aaaaggagaa ttaatatgaa gacagctttc attgcttgga
     6001 ctcctttaca tttgattaat atattaaatg tttatcaaaa tttttaccga gaatcaaaag
     6061 gagatttatt tatttattct gaatttgaaa acgctagaag atatagtgag cgtataaaag
     6121 aattagggct atttaatgat gttgtttttg tgaatcaccg gaaaatcggt tcttccttta
     6181 aacgtaaaat taacttgtta actaaccata atcaattttt ctcggatgat ttatccgttt
     6241 atgatgaaat ttttatacag ggggaaaatt atttcacaaa aatacttttc tccaatgttt
     6301 acaaaaaaaa tccagatgta aaactaaatt atatagaaga tggtttgggt acttatttga
     6361 agaagagtat attttcaaca agtaaaaacg ttcaaagagt ttttaaaata ttaaataaaa
     6421 atagcatctt caaaaaaaaa attgacgatt attttgtcta ttgtccggaa ttgttacttt
     6481 atgatgtaaa aaatataaaa aaaattccca aaatagatga aaacagtaaa ttgatgaaaa
     6541 acatacaatc aatctttggg atagaagaag tttttgtcgg agataaatgt atcttttttg
     6601 atcaaccttt attatctgat ggttatggca tagatgaaac agatattttc gctaaagtaa
     6661 atagtatatt ttctggaaaa aaagaaactt taattaagct tcatcctaga gcaaggacaa
     6721 atcgttatgg tgaaaaaaac atattgaatt ccagtttacc gtttgaagtc ttgctacttg
     6781 aaaatgactt ctcttcaaca cttttgatta gtcctatatc tacaatttct ttttcaccat
     6841 ctatgatgtt tgaaaagacg atcaactcta ttatgttggc taaattaatt ttaaatgaat
     6901 atacagcatt atctgaagat aaaaaagaaa cattgacaaa tattgttctt ttctgtgaac
     6961 attataaccg tctatcagaa gaaaaaattt tactcccaga aaactgggca gaattaagaa
     7021 agttggtaga gtatgggatt atttaacaca ctttccaagt caaaattagt taagtccagt
     7081 ttctggtata ctatagggaa tttttttatt aagggaattt cattcataac tattcctatt
     7141 tttgtaaata ttactactca agcagaatat ggtttgatta ataatttcac ttcatttgta
     7201 tcaatttttt cgattcttgt tgggctaagc ctaaattcgg caattaataa tgcaagtttt
     7261 gactataaag atgacataaa tgaatttatg tcatcggtac tttctctagc tacactttcg
     7321 ttaattgtgt tcttattaat agggaacata tattttttgt tttcaaatgc tttttttgat
     7381 atgaaccaac ttgtatttaa tttgatgtta ttacaaagtt ttgctagttt tgtaattagt
     7441 tatatccagt cttattttac gattaacttt aaccatttta aatatttgat tttatctttt
     7501 atatctactt ttttgaatat tgcaatctct gtagctttga tgcagacatt atattttgat
     7561 gataaatatg ttggcagagt agtcggcgga acactgtcat ttgtgttgat aggtttagta
     7621 atttatttaa gaataatgat aaagggtgct catttttttg ataaaaaaca gtggagatac
     7681 gctttaaaaa tctctttgcc gctaatccca cattccttag caaatatagt tttagcacaa
     7741 ttcgatagaa ttatgattaa ttcttattta ggtcctgctg cggggggaat atattcctac
     7801 attagtaaca taggtattat tctaagcgta atatggatgt ctactaataa cgcctgggtt
     7861 ccatggttct atggtgagat gagtaaaaat aatgaaaaaa aagtgaagaa agttagtaac
     7921 tattatttag tagtctttac tttgattacg atgattgtaa tggtagtttc gattgattta
     7981 gcaaaattta tggctccgaa agactattat tctgggttat ctttagtggt tccgataacc
     8041 ttaggctatt tctttcagtt tttatatagt ttaccagtta atgctgaatt ttatgagaaa
     8101 aaaacatcgt ttattacgat tggtacagta gcaagtgcta tagttaatat actattaaac
     8161 atgattttca tacctaggtt aggaataatt gctgctggat acacaaccgt atttacgtat
     8221 tttttacttt ttatttttca ttataatatc gctaaaaaaa ttacgaataa acaattattt
     8281 gacacaaaaa aaatatgtat cataataatt tttgtatcaa ttttttcttt gatacttcat
     8341 attttaatca atcaaatgtt gattcgttac gttttgacat cattattgat aattagttta
     8401 gttatatatt ttttaaagat taagaatcga attatagatg actataattc ataggaggag
     8461 atataagtgt ttaaaggaaa aacaatatta gtaactggcg gaactggttc cattggaagt
     8521 gaaattgttc gtcagctttt aaaatatgaa ccaaaagcta tcagaattta tagtagaggt
     8581 gaagaaaaac aattttatat gcaacaagag ctctcaaatc acactaattt gagattttta
     8641 attggtgata tcagagactc tcaaaggatt gattatgcat gtcgtgatgt ggatattatt
     8701 tttcatgctg ccgcaatgaa acacgttcca gcaagtgaat ataatcctat ggaagctgta
     8761 aaaacaaatg tgatgggaac tcaaaatgta atagatgcag cgatcaaaaa taatgtaaaa
     8821 cattttgtag gtatcagtac agataaagta gtgagtccta ctaacaccat gggtgcgaca
     8881 aagttattga gtgaaaaatt aataatagct gccaatcagt ataaaggaaa aacagaaaca
     8941 atattttctt gtgtaaggtt tggaaatgtc atggggtcaa gtggatctgt tattcctctt
     9001 tttagtaaac aaataaaaaa caataaagat attactttga cagatgttga tatgacacga
     9061 tttatgatgt caataccgga tgctgcaaga ttagttctgt ctgctgctat gaattcaaaa
     9121 tttggagaaa catatgtctt aaaaatgccg gcaatcaata ttttaacttt agctcaatca
     9181 ttaataaaaa tatataatga tacacatgat gaaaaatata gaggtgaaat aaaagttgta
     9241 ggtatcaggc caggagaaaa attatatgaa gagctaatga ctacagacga aattgaacgc
     9301 tcatatgaaa atgataaaat gtatatcatt ccaccacact atcatgctac tgacgaactg
     9361 tacaaagatt atgaaaaaat taaaatcact gcatactctt cagatgcaac agaattaatg
     9421 agtggacagg aatttattag aatcgcaaaa gagaataatg tcgtgacttg gtaaggagtt
     9481 ttatgatgaa atcagaagta tatgtaattg cagaaattgg tgtaaaccat aatggaagtc
     9541 tagatttagc tttagaaagt attgataaag ctaaagaatg tggagctaac gcggttaaat
     9601 ttcaaacatt taaaacgaat aagctagttt ccaaaaaggc tccaatggca aaatatcaga
     9661 aggataatct taaagaggac agttctcaat ttgaaatgct aaaaaaatta gaattatctc
     9721 aatctgattt tattagaata aaagattatt gtatacaaaa taaaattgat tttttgtcta
     9781 ctccttttga tgaagaaagt gcagactttc taaaacaaat tggtgtacaa ggatttaaaa
     9841 ttggctcagg agatttaaca aatttacctt ttcttagaaa aatagatatg tatgggttgc
     9901 cagttttatt atctacaggt atggctgata ttcatgaggt cagtgaggct gtagattgtt
     9961 tcatagatag tccagttact attttacatt gtacttcaaa ttatccggct agttctgaag
    10021 atattaattt attggcgatt aacacattaa aagaaatgtt cgggataccc gttgggtact
    10081 ccgatcattc attgggatat gatgttggta tttgtgctgt tgcgatgggt gctaaggtaa
    10141 ttgagaaaca ttttaccttg gataaggaac tacctggtcc agatcataaa gcttctttag
    10201 atcctcagga atttgcagat tttgtaaagc atattagaaa cactgaaata tttttaggtg
    10261 atggtgttaa gcgagcaatg ccttctgaac ttagtacaaa agaagtatca agaaaaagcc
    10321 tagtggtcac tgagaattta aatgtgggag atattcttac agagaaatct cttacaataa
    10381 aacgtcctgg aaatggaata gctcctaagt ttttatatca atatattggc aaaaaagtta
    10441 aaagaccaat aagtgcagat agtgttctgc ttgaggaaga tgttgaatga aaaaaatact
    10501 tatagtaagt ggaacacgag ctgattatgg aatatataaa cctgttgctg agaatttact
    10561 acaagataat tgggatgtat catttgttgt ttctggaatg catttatccc ataaatatgg
    10621 atttactaaa gaattgatct tagctgacgg atttagaatt agtggagaag ttcaaagttt
    10681 gtttttagag aacaataagg gaaacatggc tcggtctgtg gcattagaga taaatggttt
    10741 cacaaatata tttgaacaaa ctagccctga ttttgtatta ttactagggg atagaggaga
    10801 aatgttggca gctgcgatag cttgtttgta tcttggaatc aaaacagcac atattcacgg
    10861 aggcgaagtg tctggtactg tagatgaatc aataagacat gccataacga aaatagcatc
    10921 tgttcatttt gctgctacgg aaaaaagcaa agagcgttta ataaaaatgg gggaagattc
    10981 ttggagagtt tttcccgtcg gagctcctag aatagatact attttaaata atagattacc
    11041 tagttttaga gatataaaag aaaaatatca tctaaaattt gaaaagaaaa aatacgtttt
    11101 gcaagtattt catccagttg taaccgaact agaaaatata gaaaaacaaa ttttagcttt
    11161 gatcaattca atggaacaac aatctcaacc aattatttgc attttaccta atagtgatgc
    11221 tggtagcgaa attatcagaa aaatgtacca gaaatattta aaaacggata ttatttatat
    11281 tacgaattta gagccggagg aatacctgac tatattaaaa gagtgcaaat ttatgatcgg
    11341 aaattcttct tctgggataa ttgaagctgc atcattcaaa ataccagtaa taaatttagg
    11401 aaccagacaa aatggacgag aacaatctaa aaatattata aatgcaaatc taaatgaaaa
    11461 tgaaattgaa actgctttga ataaaataca agatcctcag tttataaaaa gcttgaaaaa
    11521 tgttaagaac atctacggtg acggcaacag ttctagaaga ataacaaaaa cattgaatca
    11581 aatattgaat gatggggaag atattaagtg gattcaaaaa caaatagctt attaaaatat
    11641 actagtgatc catacattat tattggggct ggcggacacg caaaagtcat tattgaaacc
    11701 ttaagattag aaaataagtt aatatatgga ttttttgatg ataagcaaaa taaaatgcaa
    11761 gatctgaaat atcttgggaa aataaacgaa ttgaatagct gggcggatag caaaaaaaaa
    11821 atctataaat ttattgtagc tattggtgac tgtgtagtaa gaaaaaagat tataaaaaaa
    11881 ttgaatatgc caagtgagca atatggaata gctgttcatc caagtgctat agtggcaaaa
    11941 gaaatttcaa ttggttatgg aactgttatt tttgcgaatg ctgtaattaa cccagatgct
    12001 gtaattggag agcatgctat aataaacaca ggtagcattg ttgagcatga ttgtagaatt
    12061 aataactatg ttcatttatc tccaggtgta tgcttagcgg gtggagtaca tgtaggtgta
    12121 ggaactcaaa taggaattgg ttctcaatgt atccagatga agaaaattgg atcttggtgt
    12181 atgataggcg cagggagcac tattgttaag gatattccct cacattcctt agcttatggc
    12241 aatccagcta aaattaagaa agaaggaatt aattttgaat tctagaattt tattatcaag
    12301 tcctcatatg ggaggaacag aagaaaaata tgttgctaag gcttttaaag ataattggat
    12361 agcgccatta ggtgaaaatg tggataaatt tgaagaaagt attacaaaat atactggttc
    12421 taagggcgga gcttctgcgt taagttcagg tacagctgcc atacatcttg ccttaagact
    12481 gcttaatgtt ggaaaaaacg atattgtctt tgctccttca tttactttta tagctacagt
    12541 aaatcctatt ttatatcaag gggctgtacc agtgttcatt gactcagaac ctaatacatg
    12601 gaatatgagc cctgttgcac tagagagcgc attagaagaa gctgaaagaa acaaccaatt
    12661 acctaaggca atcatcgtag tgaatttata tggtcaaatg gctgattatg aacgaatttt
    12721 agctattgca aaccaattta atgttccagt gatagaagat gcagcggaat cgttaggttc
    12781 tacttataag ggaatttcgt caggcttatt tgggacaatt gggatctatt catttaacgg
    12841 taataagatc atcacaacct caggtggagg agctctagtg tctagtgata aaaaatatgt
    12901 tgagcattca agatttttag caacacaagc aagagatcaa gcaccgtatt atcaacatag
    12961 cgaaataggt tataattacc gtctaagcaa tatttctgcc ggtatcggac gtggacaaat
    13021 ggaagtattg aatgatagag tagctaaacg aagagaaatt ttcaatcgat ataaggaagc
    13081 tttttctgga attgatagaa ttgaaatgat gccagaagtg gatggcatgg tgccaaatcg
    13141 ttggttgtct actttaacga tcaatgatta taattctatt gatcaagtag ttaacgtaat
    13201 aaataaacta aatgaaaaaa acattgaaac aagagctttg tggaaaccac tacatttgca
    13261 accagtattt caaggggtaa aaatgtatta ccatgataat aatcttagtg tgtcagaaaa
    13321 gttatttaat agcggcttat gcttaccttc tggaagtaat atgacagata gtgaacaaga
    13381 atttgttatt gatgagttta aaaaaatatt caagtaggtg tgatatttta tgaacatagg
    13441 aattattggt ttaggttcca tggggaaaag aagacttaga ctcattcaag aacactttaa
    13501 tgatatttta ctatgtggtg ttgatactaa tgaggcgaga cgaaaggaag ttgaaaagga
    13561 atttggaata ccaacttata atagtctaac agaggcaaaa aatttgtttg aaataaattc
    13621 agtttttgtt tgtacatccc ctataaccca tgaatttatt ataaaagagg ctttaaattt
    13681 agattgtaat atctttacgg aaatcaattt attaaatgaa tattatgatg aaataatcga
    13741 agtagctaaa aagaaagata gattacttta tctatcttct acatttttga agagaaaaga
    13801 aattcaatat attaagtcta aagtgacgca taataaaaaa atttcttatc aataccatgt
    13861 aggacagtat ttacccgact ggcatccttg ggaagattat cgcaattttt ttgtttcaaa
    13921 caaaaaaact aatgggtgta gagaaatatt cgctattgaa ttaccttgga ttatagatac
    13981 atttgggaaa gttaaatcgt ttactgtaat gacccagaaa ttatccaatc ttgatattga
    14041 ttattcggac agtttcactc ttattattga gcatgaaact ggtatagttg gaactttaag
    14101 tgtagatgtt gtttcaagag tagctaaaag aaatttaact ataattggtg aaaagatttt
    14161 aatagaatgg gaaggtaacc cggattctct attttcatgg aatgaagaaa cttctagtat
    14221 gacagatatt caattgtacg atgaggttat gcatgataat aattattcac atactattat
    14281 tgaagatgca tatttagagg agattaaaga atttttcacg cttttggaaa agaaaatgga
    14341 accccaatat acttttgaaa aagataagta tattattaac ttaattaacg acattgaggt
    14401 aaattaatga tgaaagtaat tttttttggg ttagggtcaa ttggaaagag acatctaaaa
    14461 aatctaataa gctatggaaa aaagaattct attaattttg atataacagc ttatagtagc
    14521 agtggaaaaa aagagtttga agaaataacg tatattcaaa atagagacga tttggataca
    14581 cattatgata tagcttttat tacaaatccg acttttaagc atctggaaac actaaatgta
    14641 attgttgaaa aagttgatta catattttta gaaaaacctg ctttttctga gagtattgat
    14701 cttactcaat ataattatga ttacaaaaat atttatgttg ctgctccact gaggtataaa
    14761 aatatcatgg aagttgttcg taatagtatt caaagtaaaa aagtatattc tgtaagagct
    14821 atttgttcta cttatcttcc tgattggaga aaaggtactg attatagaaa taattattct
    14881 gcctttaaat ctatgggggg aggagtagaa ttagactgta tacatgaatt ggattatatt
    14941 ataaacctat ttggtttccc taaatcagta aaaaaacagt ttggtaaata ttcgaatctt
    15001 gaaattaaca gtaatgattt agcaacatat atattgagat acgatgataa aattatagaa
    15061 attcatttag attattttgg aagagttcct acaagaaaat ttcaattgtt tactttagat
    15121 gaatgtatca atgttgactt attaaataat aaaataagtt ttgaagaaaa cattgttaaa
    15181 gaaatgcctg aatctgctaa tgatatgtat gagaaggagt tgaaatattt ctttgaaaac
    15241 gtagtaacag gcaaagaaaa ctggaatgat ttatatcatg caaacgaagt attgaaaata
    15301 gctgaggaga aataaatgga aattttattt actatttgtg gtagagctgg gtctaagggg
    15361 tttaaaaata aaaatttgaa atatttggca ggaaagcccc tagtccattt cgctttagca
    15421 atgatagata tctatcaaca aaaacatcct gaacataatt gcacgacttg tttgaatacg
    15481 gacagtaatg agttagtaga attgacgact aagttaaatc cgtctgtgaa aattgtagaa
    15541 cgtaaacctg aattagctac agatactgta gggaaaattg aagtgatacg tgattcattc
    15601 ttacaactag aaagagaaga taatatattt gatttaatta tagatttaga tttgacttca
    15661 cctttacgtg aagtttctaa tcttgaagaa ttaatagatg aacatctaaa aaatttagat
    15721 aaagacgtct acttttcagt tgtttctgca agacgtaatc cctattttaa tatggtaaaa
    15781 agaattgaaa atgaagttac tatagttaat aaatcaagat acacatctag gcaacagaca
    15841 cctgaagttt ttgaaatgaa tgcctcaatg tattctttta aacctgaatt tctaaaaaaa
    15901 agtaattata tttttgatgg gcaatgtggg ataataaaaa tgagagatta tctaatttta
    15961 gatattgata gtgaagaaga ttttaaatgg ttagaatttt tgtttcctaa atttttagaa
    16021 gattcttcgg agcttcaaga tatctataat tatttatatc ggaggtaaaa ggatgagctg
    16081 ttatcttatc accggtgggg ctggcttcat tggttctacc ttagccaatc atttaggaga
    16141 agaacatgtg gtaatcgtcg tcgatgactt atcaatggga aaagtagaaa atcttgatat
    16201 gacgaaaaat atcactttta ttgagggaga tgtcgctgag aaatccttga tggaagagat
    16261 catgaaagct aataaatttg attatatctt tcatttagca gcagttgcta gtgtggcaga
    16321 ttcagttgcc cgaccagtag aaacacatcg tgtgaatttt gaaagtgtat taatgatttt
    16381 agaattgatc cgcaagtatc aacctgattt aaaacggatc gtgtttagtt cttcagcggc
    16441 tgtttatggg gatgaaccga ctttaccaaa aaaagaagag tccgtgattc gcccattgac
    16501 gccttatgcg gttgataaat tcgctgcaga acaatatgtg ctagattatt gtcatttata
    16561 tgatgtaccc ggtagcgcag ttcgtttttt caatgtctat ggtccaaatc aaaatccgaa
    16621 ttctccatac agtggtgtga tttctattct cgtagatcgc tataagaaac aaatcgtagg
    16681 agaagcaact tcatttacat tatttggtga tggaagccag tctagagact ttgtttatat
    16741 agatgatgta atccaagcat tacttttagt tgcgaatgag gaagctgcac tggggaaaca
    16801 attcaatgtt ggaacgggta aagcaaccac acttttggaa ttgattcatg caatcaatga
    16861 aattctcggt gtagaattga cacttgaata caaagaagag cgttcgggtg atatccatga
    16921 ctctctagca gatattacta agatccagtc aattggctat caaccgaaat atggtatttt
    16981 aagtggaatg actaattatt tgaaaactga aatcaattaa aacatactaa gataagatta
    17041 gagggtaaat tcaggctctt tgtcaataag gactgatgag ttttgtaaaa tcaaatctgg
    17101 gatagaa
//
LOCUS       DAFEKH010000057        17027 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.060, whole genome shotgun sequence.
ACCESSION   DAFEKH010000057
VERSION     DAFEKH010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17027
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.060"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            510..734
                     /locus_tag="LP386_002248"
     CDS             510..734
                     /locus_tag="LP386_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919460.1"
                     /translation="MRTYWYVSLNNKYPKPMKGQHRRVVMSVQMKAKYSIVEMIREAT
                     PVEIDYCKLVYCGCGRWKEDHVQKNISKYI"
     gene            752..1180
                     /locus_tag="LP386_002249"
     CDS             752..1180
                     /locus_tag="LP386_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919461.1"
                     /translation="MEKSDTKANRYKPTAAEKKLLEVLINPDNLGKPVQELCSLAKIG
                     RTKYYDAMSKDGFVDLVNETTMDLIKGKASDVLNATYKYALTEKGHQDRKMILTIAGI
                     YADKQELKHSGGVDIRKQYEKMSDEELEELVKRYEKINDS"
     gene            1158..2576
                     /gene="terL"
                     /locus_tag="LP386_002250"
     CDS             1158..2576
                     /gene="terL"
                     /locus_tag="LP386_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit"
                     /protein_id="HBL1919462.1"
                     /translation="MKKSTTLNRVEYAVVQRELAIRKARKSFWLFCQLLYPEFYKDDR
                     LYLKDLCHTLQDFYEDKIDKKILVINMPPRHGKTFTARLFVLWMFGQNPKTKIITGSY
                     NQILSSLFAQQTRDGIMVENENVKAEYFKDIFPEVQIKYGDAAKGFWSLDGSEEKNYL
                     ATSPGGTSTGIGANYVIVDDIIKTAEEAYNERVLDSHWEWYNNTLAQRMERPRKQILI
                     MTRWSSNDLAGKMLTRRKNNVHQICYKAVQEDGSMLCNEIMTHDEYLDVVQEMNVDIA
                     EANYQQEPIDQKGRLYQKFLTYDTLPDNIIKIWNYTDTADKGADYFASPVFAETSDHD
                     AYIIDVMYTKEPMETTEIAHANMIIRNRVNKVRIEGNNGGRGFRRNSERITKERGYRG
                     AVFEDFHQSDNKLSRILANSAWVENHVYYPDDWATRWPDFYEAMVSYQREGKNAHDDA
                     PDAVTGIAETIIEADDFEFIAY"
     gene            2588..4123
                     /locus_tag="LP386_002251"
     CDS             2588..4123
                     /locus_tag="LP386_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010779952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBL1919463.1"
                     /translation="MFYSGITLKKYKRLRTKYSTQIEEGLFDPNAFMEDMKPFFDDRE
                     RKYLAYTSEKNEIDSREKPKTKIIKVNNKIHAGMYSVVVDQAVNHFTGIPIKWDYDVS
                     EQKRTFIQRMRDKLLGNDISAPSTPEEFETLTRQLSTMRFGMLDPDTATFQGATGLAF
                     RLLEPVETNDGWELRASNIEPWKAEKYENGAVYIKEKYDPYQKKFYEEMKVVTPKSIF
                     TYARYTDYPGTVQGAFKTLGNVPNPLGVINLTEFKNNTNRYCDFEVAEEISDAIDRVL
                     SDQQNEIEQFKLAYMLITGADLSEDKAKKMMEQLGIINLKDPNAKAGYVTKDLQKDFN
                     EYHFDLLKKQFYTVCKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAEVMAAYLDFAEKVTIDPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMIDVESRQSYPDGEYGGGIVESNRNEVLDQTSRTGRFSKTQNGKSNAK
                     ETK"
     gene            4203..5081
                     /locus_tag="LP386_002252"
     CDS             4203..5081
                     /locus_tag="LP386_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBL1919464.1"
                     /translation="MMEFYSTSDQKKYREYVEKNYKSLKMYDAKYKEFIEEYFPSFDY
                     AKVNRLLQMRSDIFRILAESAIDADVNKYFSDRLEDILQRSYVSNANVFAQILNVDLP
                     NYLSKEELERYLNYPWSGKTFSRRLWGNISSLEQKLSNAITTSVASGEGVLVALRTMR
                     EDPEICDMFKREESKYNKAIENLVRTEYAKFAQDGIEKSYIETGVDEYNVLTAKDEKV
                     CSICGGKAKNNPYKLSEAIIGENRAPFHGRCRCTDVPNMPKLGKDIDEEYERLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            5083..5400
                     /locus_tag="LP386_002253"
     CDS             5083..5400
                     /locus_tag="LP386_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919465.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYENMGCIVVRTDYKEGK
                     SSN"
     gene            5527..6150
                     /locus_tag="LP386_002254"
     CDS             5527..6150
                     /locus_tag="LP386_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HBL1919466.1"
                     /translation="MIMKHKSLMPMNLQYFAEGDDQKFSFDDFKSFVESNEEAQKFIQ
                     SQSQSVADKQLEAWKQNNLDKIKQDTIKEYEESKKNKSPEQIQLEKLQAEFEAEKALR
                     VTSDNKAFVAEQIAGLELDGELKESISQFMLNNLVSSDTDFTKNAVEGFTSVLNAINE
                     KHADALKELQMKSAFGGTQQSNNQVQQNNETLTNPEEQLGQILQQFN"
     gene            6165..7055
                     /locus_tag="LP386_002255"
     CDS             6165..7055
                     /locus_tag="LP386_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 domain-containing protein"
                     /protein_id="HBL1919467.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            7078..7293
                     /locus_tag="LP386_002256"
     CDS             7078..7293
                     /locus_tag="LP386_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919468.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            7305..7646
                     /locus_tag="LP386_002257"
     CDS             7305..7646
                     /locus_tag="LP386_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919469.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            7646..8017
                     /locus_tag="LP386_002258"
     CDS             7646..8017
                     /locus_tag="LP386_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919470.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            8010..8405
                     /locus_tag="LP386_002259"
     CDS             8010..8405
                     /locus_tag="LP386_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBL1919471.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGAVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            8407..8784
                     /locus_tag="LP386_002260"
     CDS             8407..8784
                     /locus_tag="LP386_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919472.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNKPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            8785..9393
                     /locus_tag="LP386_002261"
     CDS             8785..9393
                     /locus_tag="LP386_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL1919473.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            9393..9734
                     /locus_tag="LP386_002262"
     CDS             9393..9734
                     /locus_tag="LP386_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919474.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGTVVEDAAGVMEE
                     MQTATDKQSVKKALSRAYSFIADTLFEGQFTGEDYCKGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            9976..12765
                     /locus_tag="LP386_002263"
     CDS             9976..12765
                     /locus_tag="LP386_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBL1919475.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANSFVLIIGAVVGAI
                     AVFGYFMATNEEFRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVESVK
                     DAWSGIKEWFSNTWQGIKNGATGLFDKTVETSMNAVDSVKNAWSNTKQWFSDIWQSIK
                     DSATEKWNEIKGSIMEVAGPLITGLKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LTPVLFITSMISGGWEETKNNMIGVWNNIKESALNIWESIKNIFVSYITNIYFAALNI
                     WTGFKLTLINIWNEVVSQAKSIWINVKYFFINLWIDIKYFAIQKWIELKFGIIQTWID
                     LKYNAITTWNNIKQFFKDTWQNIKDIAYNTWISIKNSMINTWNNIKESFWNIVTGIVN
                     SAENAWTNLKNGVSKAINRVKEIFDSLREINLFEIGKNIIDGLINGVVEKWNALKKTI
                     KGIAGSIKDSIKGALGIHSPSRWMRDMVGKNIVQGIIVGIDKEKSKLDQTMTDLVKTP
                     SVQPVITGSNSQPVVQAKQNTSSNAVNEIHLHLNVYGDLPDSMIKQIAKKMKTELTRQ
                     MKRDADAVGGTLYAT"
     gene            12755..13495
                     /locus_tag="LP386_002264"
     CDS             12755..13495
                     /locus_tag="LP386_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL1919476.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKAYYKNVTRKIECYYKAPSIDLVQEWEDRITEWLDMNSYSDFILYYDQQYIYQ
                     AIVTEAPEFKGTRKTGNIVPFEFTVSLRPFKENYSGRFAIQQIKAFELFNPEKYASKP
                     LIKLSGSGDASFYINNDKYDLKLLDRELYIDSKLEESYRKLDDNLEHQDHVTLFLDFP
                     FLYPGKNEIKWTNNIHSFEIIPRWWRKV"
     gene            13492..16203
                     /locus_tag="LP386_002265"
     CDS             13492..16203
                     /locus_tag="LP386_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HBL1919477.1"
                     /translation="MIPRIYSPTETDFSTNGLGILKDTTKCEIYEVANGKYELELEYP
                     LGTRFDEYFENDYQIKAKSNDQEEYHIFFIDDKDIDTFLDTVTIYAQSRTNRLGRRAV
                     TFAGVDSKTGREAMAIIENNMDKKSDIRLYSDITTVSSTTFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRDNIGTIRYGKDLSGLKVKLDWTGVKTRIIPYADPQS
                     DAGTTSRIYGSPVDSEYINNYPDVYTEHVQFTEEQGVKDVNSLNKIAKNYFKTINPGC
                     DKPKISITVEFDKLTDTEEGKEFAKIRNYGLFDTFKIYHRKYKLYFESKVSGVQYDSL
                     SEKVLKLEAGDAQVAFYQQQAVTIQDKLKDYATNNYMSSFNDYVSSMIAGQGNAGGYV
                     VLWPKEKPSNIFIMDSPDLNKAKEVLRMNKNGIAFSKNGWNGPFNSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSNSSIGTI
                     GTTDSAGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVNGKEITGNNSGGSDPGTIPPQLTTEAEKRAWKIWTMLKARGYSEYAAAG
                     ILGNIQGEVGASMNPDTEQLGGPAYGIVQWDGSAYPLVGSPTWNGREYVQRLMNTAGI
                     QEDYRSIEAQVKLLDWCMFNGQWLGKVNPTTVSGFKSINDAKSAAYAFEMNFERPASA
                     HPERQNYAQSWYNKLHGLTSPEPGGNFICPIQKPVTVTSECGWRTSPINGGQEFHNGI
                     DLVNGNPNTPVFAALDGEVVQAGANYYDWYGNYVVIKHNNGKWTGYAHLSRIDVSVGQ
                     KVQKGAQIGLMGTTGPSTGEHLHFQIMKNYWPQPVVDFENPRNYIQF"
     gene            16216..>17027
                     /locus_tag="LP386_002266"
     CDS             16216..>17027
                     /locus_tag="LP386_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HBL1919478.1"
                     /translation="MSKWNVVLSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKINYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FDRWREEQENSFQDWREGQESDYLSWFESIKDILKSIDPGGVMLAELMDARVDIQGVR
                     HASISERLLADMDYLYQKLRATLFTIEYGEIEVTDILQDDLFSDNHEVEKVGT"
BASE COUNT         6068 a         2427 c         3553 g         4979 t
ORIGIN      
        1 catttatcag tgatattatg gtagtgtcga aagattagtg ataggtctga gacaaaataa
       61 taataaaagg aacatcgttt tattattgtt tcacaattaa gcttcgatag acagcaacgg
      121 aaatattaag aataaggatg tgaattttaa ctccttctaa attgttctta ttatctatca
      181 tccgttgctg tctattgtta catacagatc gcttaggcgg tctttttatt ttggccgaaa
      241 acctacattt tcgatggccg attattggag gaggaatagc atgttcaaac tatctgaaat
      301 cattaagaag tccgacgttg agaaattaga gatgttaaaa aagaagttga agaaatagca
      361 gtctcttcgt gaggctgttt tattttgctc acaaaaatag accactatcg ggtaatagtg
      421 gtcaggaatt aaatgaaaaa gatgttaggg ttgttagcta agtataacat cataacgctt
      481 acaaaacaat gcaagaagga taaattatta tgagaactta ctggtatgtg tcattaaaca
      541 ataaatatcc gaagccaatg aaaggacagc ataggcgtgt agtcatgtct gttcaaatga
      601 aggcgaagta ttcgattgta gaaatgatca gagaggcaac gccagtagag attgattatt
      661 gcaagctagt ctattgtggg tgcggccgtt ggaaagagga tcatgtacaa aaaaatatca
      721 gcaagtacat atagagaggc ggtgattaag gatggaaaaa agcgatacga aagcgaacag
      781 atacaaacct actgctgcag agaaaaaact cttggaagta ttgataaatc cagataactt
      841 aggcaaaccg gtgcaagagt tgtgttcact ggcgaaaata ggtaggacca aatattacga
      901 cgccatgagc aaagatggct ttgttgatct agttaacgaa acaacaatgg atctgatcaa
      961 aggaaaagct tctgatgtcc ttaatgccac ttacaagtat gcattgactg aaaaaggtca
     1021 tcaggatagg aaaatgattc tgactattgc tggaatctat gcagacaaac aagaactcaa
     1081 acattctggc ggcgtcgata tccgaaaaca gtatgagaaa atgtccgatg aagaattaga
     1141 agagttggtg aaacggtatg aaaaaatcaa cgactcttaa tcgtgttgag tatgccgttg
     1201 ttcaaagaga gctagccatt cgaaaagcta ggaaaagttt ttggctattc tgccagcttc
     1261 tttatccaga gttttacaaa gatgatcggt tgtatttgaa agatttatgt catacgctac
     1321 aagattttta cgaagataaa atcgacaaaa aaattttggt tattaacatg ccgcctcgac
     1381 atgggaagac ttttacagcg cggctattcg ttttatggat gtttggacaa aatccaaaga
     1441 cgaaaattat taccggatct tataaccaaa tcctgtcatc tttatttgcg caacaaacac
     1501 gtgatggaat catggttgaa aacgaaaatg ttaaggctga atactttaaa gatatttttc
     1561 cagaggtgca aatcaaatat ggagatgctg caaagggttt ctggtcttta gatggttcag
     1621 aagaaaagaa ttatttagcg acttctcctg gtggaacatc cactggtatt ggcgcgaatt
     1681 atgtaattgt tgatgacatc attaaaaccg cagaagaagc ctataacgag cgtgttttag
     1741 attctcactg ggaatggtat aacaacacgt tggcccaacg aatggaacgg ccacgtaaac
     1801 agatattgat tatgacacgt tggtcaagta atgatttagc cggaaaaatg ttgacgagac
     1861 gaaaaaataa tgttcatcag atctgttata aagcagtaca agaagacggc tcgatgttgt
     1921 gcaacgagat tatgacccac gatgagtact tagatgtggt acaagaaatg aatgtagata
     1981 ttgcagaagc caactatcag caagaaccaa ttgaccaaaa aggcaggcta tatcagaagt
     2041 ttcttactta tgatacgttg cctgataaca ttatcaaaat atggaactac accgacaccg
     2101 ccgacaaggg tgccgattac tttgcgtctc ctgtttttgc tgagacgtct gatcatgatg
     2161 cttatattat cgatgtcatg tatacaaaag agccgatgga aacaactgaa atagcccacg
     2221 ctaatatgat tattcgcaat cgagttaata aggtacggat tgaaggaaac aatggcgggc
     2281 gtggattcag aagaaattca gaaagaatta caaaagagcg aggctatcga ggtgcagtat
     2341 ttgaagactt tcatcaatcg gataataaac tgtctagaat actggcgaat agtgcttggg
     2401 tggaaaatca tgtttactat ccagatgatt gggcgacacg ttggccggac ttttatgagg
     2461 ctatggttag ttatcaacgt gaaggtaaga acgctcatga tgatgctccg gatgcagtta
     2521 caggaattgc agaaacgatt atagaagcag atgacttcga gtttattgct tattaggagg
     2581 tgggtctttg ttttattctg gaatcacatt gaaaaaatac aaacgtttaa gaacgaaata
     2641 ttcaacgcaa atcgaagaag gattattcga tcctaacgct tttatggaag atatgaaacc
     2701 ctttttcgat gatcgagaaa gaaagtatct tgcttatact agcgagaaaa acgagatcga
     2761 cagtcgtgag aaaccaaaaa caaaaatcat taaggtcaat aacaagattc atgcgggaat
     2821 gtattcagtg gtcgttgatc aagcagttaa ccatttcaca ggaataccaa ttaaatggga
     2881 ttatgatgtt tcggaacaga aaaggacatt cattcaacga atgagagaca aattactggg
     2941 taatgatatc agcgcccctt ctaccccaga agaatttgaa acactcacga gacaattaag
     3001 tactatgcgg tttggaatgt tagaccccga tactgcaaca tttcaaggag cgacagggct
     3061 tgctttcaga ttactggagc ctgttgagac aaatgatggt tgggaactaa gagcaagcaa
     3121 cattgagccg tggaaagctg aaaagtacga aaacggcgca gtgtacatta aagagaaata
     3181 cgatccatat caaaagaagt tttatgaaga gatgaaggtt gtcacgccga aatcaatatt
     3241 tacttatgct cgatatactg attaccctgg cacggtacaa ggagcattta aaacgctggg
     3301 taatgttcct aatcctttag gcgttatcaa tcttacggag tttaaaaaca atacaaaccg
     3361 ttactgtgac tttgaagttg cagaggagat tagtgatgct attgatcgtg ttttatctga
     3421 tcagcagaac gagattgaac aattcaagtt agcttatatg ctgatcactg gggcagattt
     3481 gtccgaggat aaagccaaga agatgatgga gcaactaggg atcatcaatc tgaaagaccc
     3541 taatgcgaaa gccggctacg tgacaaagga tctacaaaag gatttcaacg agtatcattt
     3601 tgatcttctt aaaaagcaat tctacacggt gtgtaaagca attgatttca atgacgaagt
     3661 ctttaagtcg aatagttctg gggaagcccg aaagtggcaa atcattagtt tagaagctaa
     3721 gacaaatacc aaagaacagt actttcgaga aggattgaaa gagtgtgccg aggttatggc
     3781 tgcttatttg gattttgccg agaaagttac aattgatccg gaaaagatca ttttcacctt
     3841 ctctcgttcg cttccaacag atttaagcta cctagctgag gcattgccta agttggcacc
     3901 atacgtttct aagaggacga ttcaaagtca gatcccgttc gtcacagatg ttgattatga
     3961 aaacgaaatg attgacgtcg aaagcagaca atcttaccca gacggcgagt atggaggtgg
     4021 catcgttgag tcaaatagaa acgaagtact ggaccaaacg tcgagaactg gaagatttag
     4081 caagactcaa aatggaaaat caaacgctaa agaaactaag tagtgtcttt cctgatgcgt
     4141 tgaaagaaat tcaagcggag ttattatccc aagctgattt acacgatatt acctatgctg
     4201 agatgatgga attttatagt acaagtgatc agaaaaaata tcgtgaatac gttgaaaaga
     4261 actacaaatc actgaagatg tatgatgcaa aatacaaaga gttcatcgaa gaatactttc
     4321 cttctttcga ctacgccaaa gtgaatcggc tgcttcaaat gaggtcagat atttttcgaa
     4381 ttcttgcaga gagtgcaata gatgcagatg tgaataaata tttttcggat cggttagaag
     4441 atatcttgca acgttcgtat gtatcaaacg caaacgtatt tgcccagatt ttgaacgtag
     4501 atttgccgaa ttacttatca aaggaagaac ttgaacgtta cctgaactat ccttggtcag
     4561 gtaagacatt ctcgcgtcgt ttatggggca atatttcatc tctagaacaa aagctatcta
     4621 acgccattac aactagtgta gcaagtggcg aaggagttct cgtggcatta cgaacaatgc
     4681 gagaagaccc agaaatatgc gatatgttca aaagggagga atcgaagtac aacaaggcga
     4741 tcgaaaatct tgtgagaaca gaatacgcta aattcgctca agatggtatt gagaaatctt
     4801 atattgaaac tggcgtagac gaatacaatg tcttaactgc aaaagatgaa aaggtatgtt
     4861 caatatgcgg tggcaaagca aagaacaacc catacaagtt gagtgaagcg atcattggtg
     4921 agaaccgtgc gccttttcat ggccgatgca gatgtacaga tgttcctaat atgccgaaat
     4981 taggaaaaga tattgacgaa gagtatgagc gtttatttgg cgatttatta gatgagtttg
     5041 cacatgattc ttttggaatt aatttgaaac ggaggaagta gaatgaaaga tttttttgaa
     5101 gcagtactaa caattaatgt aaatgctgat attgcagaag cctacaaaac agctattgag
     5161 tctgagaacc atcctaatgg cttgagagac cattggaatg gcaattatgc ctacgtggtt
     5221 attggcgatc aaactgttaa ttatcaagat aatactccag ttgataagaa taccgttaat
     5281 ttaacgattc aattattatc tcattcatta ccaaatttaa aagaaacagt tgattggtat
     5341 gaaaatatgg gatgtattgt tgttagaact gactacaaag aaggaaagtc tagtaattag
     5401 gcttttttat tttgtccgaa atgacgttaa actagcgcaa tactgggctt ggttgaatgg
     5461 tggggcgcaa ctattaaaac tcaaagcaat gcggggcgtg aaaacgaatc gtggggcgaa
     5521 aggagaatga ttatgaaaca caaatcatta atgccaatga atttgcaata ctttgccgaa
     5581 ggtgacgatc aaaagttttc ttttgatgac ttcaaatctt ttgtggaatc caatgaagaa
     5641 gctcaaaaat ttattcagtc acaatctcaa agtgttgccg acaaacaatt ggaagcttgg
     5701 aaacaaaata acttagataa aattaaacag gataccatca aggaatatga ggaatctaag
     5761 aaaaacaagt cacctgagca aattcaactg gaaaaactac aagctgaatt tgaagcagaa
     5821 aaagcgttgc gtgtgacaag tgataataaa gcatttgttg cagaacaaat tgctggatta
     5881 gaactagatg gagagttaaa agagtctatt tctcaattta tgctaaataa tcttgttagt
     5941 tcggatacag atttcactaa gaatgctgtt gaaggtttta caagtgtttt gaatgcaatt
     6001 aatgagaaac atgcagatgc attaaaagaa ctacaaatga agtctgcatt tggtggaact
     6061 caacaatcga ataaccaggt tcagcagaac aatgaaacat taacaaatcc agaagaacaa
     6121 ttaggacaaa ttcttcaaca atttaactag gagagtgaaa aattatgaaa aaaacatctt
     6181 taaataattt agagtatttg gatatttcac cagcgattaa tgctatgcaa gtaccaaata
     6241 cacctttttt aagctattta cttggtgctg gaaaaacaga gccagcaaac tcgacagaaa
     6301 ttaaatggcg tgaatatgat atcaacaacg atgattcttc tgaaaaactt gagggcggag
     6361 aatatccaga tgctgaatca ggtcgaactt ggtttaacaa ctatactgaa atttttagaa
     6421 aatcaacctc tgtatctggt acattagatg ctattaatgt gaatggagtc ggaaatgaat
     6481 taactaatca agtagcacta cgtggtatgg aaatgaaaat tgatttgaac cgaaaattga
     6541 ttactggtgt aaaagctgat gaaaatggtt ctaaaggtcg tcgaatgaat gggattttga
     6601 acttgatcaa ttcagcaaat aaggcagaaa cagccactgc gggtgcagta acaagaaaag
     6661 atatcgatac tttatttaaa ttgatgtatg aaaaaggtta tatgggagaa aaactatgct
     6721 tgatttctcc agatatgcag gagttaatga ctgatgagtt agatggaaaa tcaacaaaaa
     6781 ttgttcagtt cggggaaaga gtaacttttg gattgcaaat tggaaatatc gtgtctaatt
     6841 acggtacagg tattgctcta ctagaaccat cattgccaaa aggaacaatt gccgcaatcg
     6901 atactaatta tgtgaaacta cgtccattac gtgaatggag agcagaagaa cttgcaaaaa
     6961 caacggattc tagacgtatc ggtcttgtag gtgaatactc tcttgaatac aatgcttcaa
     7021 actctggggc aattttaaat ttaaagtctg aataaaaggg agttagtact cccttttttg
     7081 ataggaggaa ttacagtggt aaaaaaagat gaaactaaaa aagatgaagt cgtgaaatat
     7141 agagtaggta aaactaaaaa ttttgttggg tttgttcatc ctaaaactcg tagatttatc
     7201 acagcagatt caaataacga atttatcatt tctatagatg ataaagaagc aattgcaatt
     7261 ttggaagatg caattgatgt taatgaaatt taggaagtga tctgatggat gaatcgctaa
     7321 aaacggaaat cattgagtct acaaaagaag attttccaga tttgagtgaa gaacgcataa
     7381 ctaatttatt agaaataatt ttgctagaaa ttgaatcata caacacttgt aaaaatgata
     7441 tttcatggga aaagttaaaa agcgtgatta gtgaagtgtt gtataaaata ataaaaaatg
     7501 aatcagaaaa aacagtatct tcagttagac gtggcgatac aacgattagt tatgcttcaa
     7561 caacaaatga tgttagtgag ttacttctag gctatggtga tttgatacga agagttattg
     7621 gttgtggagg attggagttt ttttaatgaa tgaagcagat attttagaaa ctacttatga
     7681 agatagttgt attattgaaa gactgacgga cattgaagat tctaatacaa atattactat
     7741 tcaagattac aaaaaagtat atgataatcc tatttcttgc gctctttcac aaggtcaaat
     7801 cgatggacta gcagtcatag aagatggaga gatggtaaat gtttcaactg acacatataa
     7861 attatttgtt catcctaaga ttaaactaaa aaaaggagat cgaataacaa taactcaaaa
     7921 ggccagtggc ttaatttttt ctctatttgc tactaagcct ttttactatc ctagtcattg
     7981 tgaagtgaat ttgataggaa gtgagaaaaa tgggtaatct caaatatgaa tcaaatgcag
     8041 aaaagatcat tgagaatttt aaaaatatga ctgtaattgc tcaaaaagaa ggaatatcct
     8101 tcgttaacga ttcaatgaat aaagtcgtta gtttagctaa accattaact cctgtaaaat
     8161 caggtaattt aaggcgagga tatcgtgtag taaaagctag aaaactatca agcggtcgaa
     8221 ttgttggagc agttataaac aatgaacatt attttaaata tgtagaagaa ggtcatagga
     8281 ctaaaaatgg tggctttgtc aaagggaaat tcatgttaac tcgtgcaacg aatcttgcaa
     8341 atatgtctta tattcctcga agatttaaac aaatggcaat aaaaatcgtt aagaaaggaa
     8401 agtaacatga aagatgaaat cattgctgca atcagtagca aattaaaaga aatctatcct
     8461 gatgggacaa tatatcttga ttcagttatg cagtcaacta aagattttta tttcgtttta
     8521 tcagtaatgg aatctggaac tgaaaatgta ggaattgata ttcaaaatgt ttctttctta
     8581 attgatattg cattgattga taataaacct aatagaaatt taattaatga attagtctca
     8641 cgttgtggga ctttttttaa tacgattaca atcgatgagc aaatattatt tccaaaagcc
     8701 tatttacctg atgaagcaga tggtgttcaa catattcgtt ttacattaga atttccacaa
     8761 tatattgaat ggagtgaaag ataaatggga gaaaaaagaa gtaaaaccgg aattatttct
     8821 gtcgaaaaac ctacttggtt tcctttggaa gatgagacag ggaatttccc ggtatatggt
     8881 actgcgttgc caatgggaac agcagtaagt atcaaaccaa cagctaatta tgaaacaaca
     8941 caagattatg gggattcagt ggttcaagat caatttacag cttttggtgg tgcagaagtt
     9001 gaactggaag caaatggata tactcataaa gttttatcta caattactgg agggaaaatt
     9061 gttaaaggtg gtgccttgcg ttctggagaa gatattgcgc aagatggtgc gtttgcatat
     9121 agacgtaaaa aatcgaatgg gaaataccgt tatacggtct tttataaagg acagtttgct
     9181 ctagattcag atgaaacgtc aacgattgaa ggaagtaaag taagttttac tcatccaact
     9241 tggaagggtt catttgtaga tgtaccagga cttggatata tgtattcagt tgatgaagat
     9301 gatgaaggcg tggataaagc aatgatcgga aattggttta caaaagtagc aattccaatt
     9361 gaagaagcag aactttcagg aggtacagaa taatgtcaaa atatcaaaca acgattaaat
     9421 taacgaaaaa agatgaagaa ggtaaatatg agcaagtaca atttaaatct gctgaatttt
     9481 taccaggaac agttgtagaa gatgctgcag gagttatgga agaaatgcaa acagcgactg
     9541 ataaacaatc agttaaaaaa gctttaagtc gtgcttattc atttattgca gatactttat
     9601 ttgagggaca atttactggt gaagattatt gcaaaggaat tgatgctcgt gagattgcct
     9661 cattgacagg aaaattattg aagtctgtta ctgcaggttt tgatgaaact tatacagaga
     9721 cgaaaaaaaa gtaagtgagg cgctcaagtc accttcattt aagtattcga ttacttaccg
     9781 agaattagat ataaagacgc aattactcga agcaggttgg acgttaccag aaattgaacg
     9841 tactgacttg gatgagttaa tgcgtctttt tgcttttaga gatgcggtaa aagagcatga
     9901 agatgttgag tactatgata atttcactca attttaggag gtgatacttt gaataacgat
     9961 gacctaattc tgaagatgat actagatgaa tctggtttta ctgccggtat gaataatgct
    10021 gtcaaaaagt tgaactcttt tgatgaaaca atcgaaagaa aaagtagaaa tagtggcagt
    10081 tcattaggta gtatttggaa aatatttgct ggaagttttc tagctagcgg agtaactaga
    10141 atcgtaggag ctggctttga tctaatcaag ggttccataa gtggagcggt tgatcgagta
    10201 gatacgatga ataacgctct acgaaatttc caaaatatgg gatttagtaa ttcagaaatt
    10261 atgaagaata tcggaaagaa tgggctttta tctcaaggta ttcaaggact tcctactgct
    10321 ttgaatgatg cgataagtca tgttcaactt cttgcttctt ctacaggtga tttaactcgt
    10381 tcaactcaaa tatttaaagc tttaaatgat ggaattcttg gtttcggtgg ttcaactgat
    10441 caagttaatg aagctgttat tcaattatct caaagtttct caaacggaaa agtagacgca
    10501 caaacttgga actcaatgat caacgctcaa cttggaccta ctctttctgc tattgctaaa
    10561 aagatgggaa ttacaatggg agatctgaaa gaaggtttat ctcaaggtaa gatttctgtt
    10621 gaagaattcc aaaatcaatt aatagaaatg gataccaaag gtggcggagg acttaaatca
    10681 ttaagtcaaa tcgctaaaga ttctactaag ggaattaaaa cctctataca aaatgcaaaa
    10741 acagctgtta cacgtggtgt tggtgaggta atagaaggat taaataaagc attagtagat
    10801 tcagatttag gtggatttaa gggaattatt gataaagtgg gcagttcaat ggaatcgttc
    10861 ttaaaagtaa ttgctgcaaa tattcctaca gcagtatcat ttttaagtaa tttatttaac
    10921 gaaattcaaa aatttggttc tgctttgaaa ttcatgatgc cctttcttgt tcctgcagct
    10981 accgcttttg gagcgttcat gtttcaactt aaaggtatac cagcaataat aaaaagcttc
    11041 aataatttta agaatgccat aattggcgtt ggaaattcat taaagattat gggggcaata
    11101 gctgctgcta attcatttgt tttaattatt ggtgcagtcg ttggtgcaat agctgttttc
    11161 ggttacttta tggcaaccaa tgaagagttt agaaacaagg ttatatctat ttggaatgat
    11221 gtgaaagatt ccgtaattgg tgtattaaaa aatataaagg actggggaat tgatacttgg
    11281 aattctgcta aagaaatggc atcaaatgct gttgagagtg tcaaggatgc ttggtctgga
    11341 ataaaggaat ggttttcaaa tacttggcaa ggcattaaaa atggagcaac aggtttattt
    11401 gataaaacag tagaaacatc tatgaatgcg gttgatagtg taaaaaacgc atggtcaaat
    11461 acaaagcaat ggttttctga tatttggcag agcataaaag attcagcaac tgaaaaatgg
    11521 aatgaaatta aaggttctat catggaagtt gctggtccat tgattacagg tttaaagaac
    11581 gcattcttgc atgtcacttt ttatttagag accttatgga ataatctagt tgagattggt
    11641 aaaaatgttt ttgagatttt aaaaaatgtt atacttacgc cagttttgtt tattacctcc
    11701 atgatttctg gtggatggga agaaacaaaa aacaacatga ttggtgtatg gaataatatt
    11761 aaagaaagtg ctctaaatat ttgggagtct ataaaaaata tttttgttag ttacattaca
    11821 aatatttatt ttgctgcgct taatatttgg acagggttca aacttacttt gataaacatt
    11881 tggaatgaag tagtaagtca agctaaatca atttggatta atgtaaaata cttttttatt
    11941 aatctttgga ttgacattaa gtattttgct attcaaaaat ggattgaatt aaaattcggg
    12001 attattcaaa cttggattga tttaaaatat aatgctatta ctacttggaa caatattaaa
    12061 cagttcttca aagatacttg gcagaacatt aaagatatag catacaatac atggatttct
    12121 ataaagaatt ccatgatcaa tacttggaat aacatcaagg aatctttctg gaatattgtt
    12181 actggaattg ttaactccgc tgaaaatgca tggactaatc taaaaaatgg tgtttcaaaa
    12241 gcaattaatc gggtgaaaga aatctttgat tcattaaggg aaatcaattt attcgaaatc
    12301 ggtaagaata tcattgatgg acttatcaat ggtgtagtag aaaaatggaa tgcattgaaa
    12361 aagactatta aaggaatagc tggaagtatc aaagattcta ttaagggtgc attaggtatt
    12421 cattctccat ctagatggat gagggatatg gtaggtaaaa atattgttca aggtattatc
    12481 gttggtattg ataaagaaaa aagtaaattg gatcagacaa tgactgattt agtgaaaact
    12541 ccgtcggttc aaccagttat tacagggtct aatagtcaac cagtggtaca agctaaacaa
    12601 aatacatctt caaatgcagt gaatgaaatt cacttgcatt taaatgttta tggagatcta
    12661 cctgattcga tgattaaaca aatcgccaag aagatgaaaa cagaattgac gagacaaatg
    12721 aaacgagatg ctgatgcagt aggagggaca ttatatgcaa cttaaaagag gacaattttt
    12781 tatcaatcaa cattattctt ctgagtttaa cgtatatatt caaaataggc ctgcctctgt
    12841 ttcagctagt cgtgtaattg aattgagaga acgtgaaggc aatgactcaa ttattatcga
    12901 taaagcctat tacaaaaacg ttactagaaa aattgaatgt tattacaaag caccatcgat
    12961 tgatttagtg caggaatggg aagatcgaat tactgaatgg ttagatatga actcttacag
    13021 tgattttatt ctttattacg atcaacaata tatctatcaa gctatagtaa ccgaagcgcc
    13081 agaatttaaa ggaacaagaa aaacagggaa catagttcca tttgaattta cagttagtct
    13141 tcgaccattc aaagaaaatt atagtggtcg ttttgctatt caacagataa aagctttcga
    13201 gttatttaat ccagagaagt atgcttcaaa accgcttatt aaattgagtg gttctggaga
    13261 tgcttctttt tatattaata atgataaata tgatttgaaa ctattagata gagaattata
    13321 tatagattct aaactagaag agtcttatcg aaagctagat gacaatttag aacatcaaga
    13381 tcatgtcact ttatttttag attttccatt tctataccct ggaaaaaatg aaatcaaatg
    13441 gacgaataac atacattcgt ttgagataat accaaggtgg tggagaaaag tatgatacca
    13501 agaatatata gtcctaccga gacagatttt tctacgaatg gtttagggat tttgaaggac
    13561 accacaaaat gtgagatata tgaagtagca aatggaaaat atgaattaga gttggagtat
    13621 ccattaggta ctcgatttga tgaatatttt gaaaatgact atcaaataaa agcaaagtca
    13681 aatgatcaag aagagtatca tatctttttt attgatgata aagatattga taccttttta
    13741 gataccgtaa ctatttatgc ccagagtcgt acaaatcggc ttggaagacg agcggtcact
    13801 tttgctggag tcgactctaa aactggtcga gaagcaatgg caattattga aaacaatatg
    13861 gataaaaaat cagatatacg cttatattct gatattacaa ctgtatcaag tacaactttt
    13921 gaagcaagaa atgttttaaa ttgtattgct ggtgaacaag gatctttact tcagtattgg
    13981 ggcggagaaa ttaaacgtga gccttttaag ctatctttat taaagcgaag aggtcgtgat
    14041 aatattggca caatccgata tggaaaagat ttatctgggt taaaagttaa gttagattgg
    14101 acaggcgtga aaacaagaat tattccgtat gctgatcctc aaagtgatgc aggtacaact
    14161 agccgaattt atggctcgcc agtagatagc gaatatatta ataattatcc tgatgtatat
    14221 acagaacacg ttcaattcac agaagaacag ggagttaaag acgttaatag cttaaataaa
    14281 atagctaaga attatttcaa aacaattaat ccaggctgtg ataaaccgaa gatttctatt
    14341 accgttgagt tcgataaatt aacggacacc gaagaaggaa aagaattcgc taagataaga
    14401 aattatgggt tatttgatac gtttaaaata tatcatcgaa aatataaact atattttgaa
    14461 tcgaaagtta gcggtgttca atatgattca ttatctgaaa aggttttgaa attggaagct
    14521 ggggatgctc aagttgcttt ttatcaacaa caagctgtta ctattcaaga taaattaaaa
    14581 gattatgcta cgaataatta tatgagtagt tttaatgatt atgtgtcctc tatgattgca
    14641 ggtcaaggaa atgcaggcgg ttatgtagtt ttatggccaa aagaaaaacc ttcaaatatt
    14701 tttataatgg atagccctga tttaaacaag gcaaaagaag tattaagaat gaacaaaaat
    14761 ggaattgcct tttctaaaaa tggttggaat ggtcctttta attccgcttg gacattggat
    14821 agtatattca atgctaattt tattcaaaca ggattaataa aggcagatat ctttcaaaac
    14881 tcttttaata aaactggaga tgtattgaaa ttagttaatg gactacttca aatttggaat
    14941 aacaaaaaga aaataatgga gttaaccaaa aaaggaatgg agttttggaa ttctaatagt
    15001 tcaattggaa cgattggaac aactgattct gctggtaatc cttttcctgg agcttctact
    15061 cccacaccta ttgaagataa ttctttagtt attcgtacaa atggagacgg caaatatatt
    15121 ttgatttctc ctaaagttgg taaaggatta gttttattag gaaatggtaa agcaatttat
    15181 tttggagact tagatgtaca aggcaaactc acagttaacg gaaaagaaat cacagggaac
    15241 aacagtggag gaagtgatcc tggaactatc cctcctcaat tgacgacgga agctgaaaaa
    15301 agagcatgga aaatttggac aatgctgaaa gctcgtggct attctgaata tgcagctgca
    15361 ggtattctag gaaatattca gggggaggtt ggagcaagta tgaaccctga tacagaacaa
    15421 cttggtggtc cagcttatgg gattgttcaa tgggatggtt ctgcttatcc gttagtcgga
    15481 tcaccaactt ggaacggacg agagtatgtt cagcgtttga tgaacaccgc agggattcaa
    15541 gaagattatc gaagtattga agcccaagta aaattattag attggtgtat gttcaacggt
    15601 caatggctcg gaaaagtaaa tccaaccaca gtatcaggat ttaaatcgat caatgatgcc
    15661 aaaagtgcag cgtatgcttt tgaaatgaac ttcgaacgcc cagcttctgc acatccagaa
    15721 cgccaaaatt atgcccaatc ttggtataac aaattacatg gattaactag tccagaacct
    15781 ggagggaatt tcatttgtcc aattcaaaaa ccagtgacag ttacttcaga atgtggatgg
    15841 agaactagtc caataaatgg cggccaagaa tttcataatg gaattgatct tgtaaatgga
    15901 aatcctaata cacctgtttt tgcagcatta gatggggaag ttgttcaggc tggtgctaat
    15961 tattatgact ggtatggtaa ttacgtggtt attaaacata ataatgggaa gtggacaggt
    16021 tatgctcatt tgtctcgtat tgatgtttct gttggacaaa aagtccagaa aggtgctcaa
    16081 ataggcttga tgggaacaac tggtccatct acaggagaac atctacattt tcaaattatg
    16141 aaaaattatt ggccacagcc agttgttgat tttgagaatc caagaaatta tatccaattt
    16201 taaggtggtg attctatgag taaatggaat gtcgttttaa gtacaacaga accatataat
    16261 tatgtgggga tgattcaagt tcgacaaggc aataagaata cagaggttat ggaagcgact
    16321 atagttgaaa atggtcttcc ctacgattta tcagaatgta aggtatattt tgaatcagtt
    16381 gtaggtggga aatatccagt ccaattagaa acaaaaattg tggatgctaa aaaagggaaa
    16441 attaactata tttttgataa atattccatg cagtgtttgc atcgacaaac agccaatttc
    16501 attatattta aaggagaaga cttgattgga acaactcaag acttctccta ttttgtcatc
    16561 aatgctgttt caaaaacaga aggagaaatg ggttcttatt ggcaatcaat tgaagattta
    16621 attgctgata tgacagattt tattaatgaa aataaaggcg attttacgga ctggatgaat
    16681 gaaaggaaag aagaatttga tcgctggaga gaagaacagg agaatagttt ccaagattgg
    16741 agagaaggac aagaatcaga ttatttgtca tggtttgaat caatcaagga tattttgaag
    16801 tctatcgatc caggtggagt aatgttagcc gaattaatgg atgcacgtgt tgatattcaa
    16861 ggagttcgtc atgcgtctat ttcagagcgc ttgctggcag atatggatta tctatatcag
    16921 aaattacgag caacactttt cacgattgaa tacggtgaga ttgaagtgac tgatattttg
    16981 caggatgatc tcttttcaga taatcacgaa gtcgaaaaag ttggaac
//
LOCUS       DAFEKH010000058        17005 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.061, whole genome shotgun sequence.
ACCESSION   DAFEKH010000058
VERSION     DAFEKH010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17005
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.061"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..124)
                     /locus_tag="LP386_002267"
     CDS             complement(<1..124)
                     /locus_tag="LP386_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HBL1919479.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVF"
     gene            complement(228..539)
                     /locus_tag="LP386_002268"
     CDS             complement(228..539)
                     /locus_tag="LP386_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBL1919480.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(541..738)
                     /locus_tag="LP386_002269"
     CDS             complement(541..738)
                     /locus_tag="LP386_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HBL1919481.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1132..2859)
                     /locus_tag="LP386_002270"
     CDS             complement(1132..2859)
                     /locus_tag="LP386_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HBL1919482.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2852..4045)
                     /locus_tag="LP386_002271"
     CDS             complement(2852..4045)
                     /locus_tag="LP386_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HBL1919483.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4232..4876)
                     /locus_tag="LP386_002272"
     CDS             complement(4232..4876)
                     /locus_tag="LP386_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL1919484.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4970..5104)
                     /locus_tag="LP386_002273"
     CDS             complement(4970..5104)
                     /locus_tag="LP386_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HBL1919485.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(5106..7238)
                     /gene="feoB"
                     /locus_tag="LP386_002274"
     CDS             complement(5106..7238)
                     /gene="feoB"
                     /locus_tag="LP386_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBL1919486.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7235..7708)
                     /locus_tag="LP386_002275"
     CDS             complement(7235..7708)
                     /locus_tag="LP386_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBL1919487.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8109..8333
                     /gene="nrdH"
                     /locus_tag="LP386_002276"
     CDS             8109..8333
                     /gene="nrdH"
                     /locus_tag="LP386_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HBL1919488.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8492..10651
                     /gene="nrdE"
                     /locus_tag="LP386_002277"
     CDS             8492..10651
                     /gene="nrdE"
                     /locus_tag="LP386_002277"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HBL1919489.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNSLYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10701..11666
                     /gene="nrdF"
                     /locus_tag="LP386_002278"
     CDS             10701..11666
                     /gene="nrdF"
                     /locus_tag="LP386_002278"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HBL1919490.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11755..12894)
                     /locus_tag="LP386_002279"
     CDS             complement(11755..12894)
                     /locus_tag="LP386_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL1919491.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13203..13916)
                     /locus_tag="LP386_002280"
     CDS             complement(13203..13916)
                     /locus_tag="LP386_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBL1919492.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14170..14871)
                     /gene="nagB"
                     /locus_tag="LP386_002281"
     CDS             complement(14170..14871)
                     /gene="nagB"
                     /locus_tag="LP386_002281"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBL1919493.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            15105..16637
                     /locus_tag="LP386_002282"
     CDS             15105..16637
                     /locus_tag="LP386_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBL1919494.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16828..>17005)
                     /locus_tag="LP386_002283"
     CDS             complement(16828..>17005)
                     /locus_tag="LP386_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL1919495.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5278 a         3495 c         2908 g         5324 t
ORIGIN      
        1 aaaaaacaca ttccactaaa tttgatgccg gttttccttg aggttttgtt ccagcacctc
       61 ctttaatttt tttaagctct tgatctgaac attgtttagc atttagtcta tttttttctt
      121 ccattacgat tccccctaca aactataaat acttttatgt cactgattca atatacctat
      181 ttttctaatc aaaaaatttt gagacatatt taatattata agtatcatta aaattgagat
      241 ttatctccat aatctgctcg atataaacca tttattccag cagttcttcc aatttcactc
      301 aaatttctta ttaattcctc ttgatattca gtgaatctta ttttattagt ataagcagta
      361 aaatatagat aattcaccaa tctatttatt aaaggactgg gatctaattc atatttttgt
      421 ttttctaatt ttaaatatac cttttgtaaa acctcaagaa tatcagaata tttaggatct
      481 ttacttatag atatatcatt atataattca tgaacaattt gcttagcatt ttttttcatt
      541 ttagcacttc cctggaattg ctccacctaa aaaaccacct atagacattc ctgcaataca
      601 agtagttgcc ttggcccaat cgaccgtaca tttattttta gtgcaataca ctccatttcc
      661 ataatatttt ccactatgag tggtaccccc atagataagt tgtgtctctt taatagacaa
      721 aatttttaaa tgtttcataa tctaatcacc cctaaattaa tgtttttaga ctattattct
      781 aacattcatt aaatttcaaa aaacaattcc ttcttgaaac gtagcaaaat aattcctgaa
      841 taagaattta atcactttta agtatataaa ctatgtatat tctttaatat tttttgagaa
      901 tgcacttcgt acataataaa ctttaatcac attagtcttt catacctacg atcgatctct
      961 ttgactcgca cccataaatt cataatagtt tgtcggcgtc tttgaacgtt tcgaagatga
     1021 gctacgcatt ctcttttttt atagacaaaa aagatagaga cgaacatgga gcttccaaat
     1081 ttggatattt gatccaattt tggaagctcc atttatttcg tgtctgtctt tttatttttt
     1141 ccagctttcg actaattctt ggttctcttt gatccagtct tttgctgctt gctgtggatc
     1201 ttttccattg ttgatttcca acataacttt ttccatatct ttttctgacc aatggaaatt
     1261 gtctaatact ttgtaagctt ctggctggtc ttctttcaat ccttttcgaa ccatcgtatg
     1321 gatctgctct tcgcttccca ttccgttttc aggatcttct aagtatttca gatcatattt
     1381 ggcaaacatc caatgaggtg tccatcctgt aactacaatt ggttcgtgtt ttttgatcgc
     1441 ttgacctagt gcaacggtca ttgctcctga agaagatgtc tctactttcc agtctttcaa
     1501 gttgtcatat ttttggatcg tgttttcagc agccgtaact acaccagctc ctggctcgat
     1561 tcctatgatt ttcttacctg cctgatcggt taactcatcg atcgaattta catccatgta
     1621 ggctggcact gctaaaccaa cttttgctcc tgtcaaattg gcacctaggt cttcgacttg
     1681 atctttatat tgtgcatatt gtgaaccatg agttttaggt agccaagctg aaaccatggc
     1741 atctgactcg ccatttgaaa cagatttcca catgattgaa ttatctaatg gcgtcatcgt
     1801 tacatcatag cccatttgtt tcaatacttc accgactaca tttgttgaag caacttctgt
     1861 atcccattca acataagata agttgatacg ttttgtttct ttggcagatg aaaaactccc
     1921 tataccaatc gcacctaaga tcactactac tacagcacca atgatcagtc cttgacgttt
     1981 tttacttttc tgtgttgttg ctcctgcagc ttttttattg tttggctggt tcaaatgctg
     2041 tgtaaaacgg tcaatgatga ttgctaagat aactaatgca accccgttga caaatccatt
     2101 cccgacttgt gctctttgca atgctgataa tacgccgcgt cctaagccgg gtgcaccgat
     2161 catagaggca ataacgacca ttgaaagtga cagcattgtt gtttgattga tccctgccat
     2221 gatcgtactt ttagctaaag gcaattctag tttgaatagt ttttgacgac ttgtgctccc
     2281 gaatgaatca gaagcttcta ctaattcttt aggaacttgt cgaatcccta aattcgtaaa
     2341 acgaacggtt ggtggcagag caaagatgac tgaggcaaat acccctggaa ccatcccgat
     2401 accgaaaaat gcaactgctg gaatcaaata aacgaatcct ggcattgtct gcataaagtc
     2461 aaggatcggt ttgataatac tttgggcttt actgcttttt gccatcaaga tccctaatgg
     2521 taccccaatg atgatcgaga tcacactaga taaaagaaca agtgtgacag tattcatcaa
     2581 atcattccat agaccttggt tataaataaa ccatagaccg attaatgtga acaacgtaag
     2641 tcctggacgt ttcttagaaa taaagaaagc tgctaccgtc aataacaaga taaacaaagg
     2701 agctggaatc actaacagta aatttgtaat ccccgacatc actgcctgtc caatcgtttg
     2761 taaaaatgaa aataggccag aaaaagttgt cgtaaaccat tctgtgatat tttctaccca
     2821 gtttgccact ggtaattgat agttcaatag attattcatg ttcactcacc tcgcttgttt
     2881 ctgctaatgc ttcaatcaca ctacctcgga tgacgacacc ttttaatttt ccatcctcta
     2941 caactgcaag tggagtcggt gagtcataaa taatattgaa aatatcactt accaccatgt
     3001 ctttcccaat caccgtcaca ttttcatcta ggaagtcgat caatggacgt ttttgcttcc
     3061 tagcttctaa cgcttgatct gcagtgatga tccctttcag gtgtctcttt ctgtcaacag
     3121 ccatcagcat gctgacttct tcattacgca tccttgtcaa tgcaacgttt ggtccatcag
     3181 attcgatatt cgtcgtcaat gcaggtacca tgatgttttg agccgtaagc actttggaac
     3241 gatcgacttc ttccacaaat tcacgtacat aatcatttgc tggattggtc aatatttctt
     3301 cacctgttcc gatctgcatg atttcgccgt ctttcatcaa ggcgattctg tccccaatcc
     3361 gtaaagcttc attcaaatca tgggtaatga aaataatcgt tttttgaaca ttggcttgca
     3421 ggtccagtaa ttcgtcttgc atttctcgcc ggatcagcgg atcaagagcc gagaacgctt
     3481 cgtccatcag caagatctca ggatcatttg ctaaagctct ggctaggcca acccgttgtt
     3541 gcatcccacc agataactga ctaggatatt ggtctttaaa tgaaagcaaa ctagaatttt
     3601 ctaatgcttt ttctgctttt tcttgtcgtt cttctttagg tacaccacgg acttctaacc
     3661 cgtattctgt attttccaag atcgttcgat gtggaaacag accgaagttt tggaaaacca
     3721 tattgatttt atgacgacgg acttctcgca attcttcttt gcttaacttc gatacatctt
     3781 ctccatcaat atagatactg cccgaagttg gctcaatcag acgattcaat agacggatca
     3841 atgtggattt cccactcccg gaaagcccca tgatcacgaa gatttctcct tcttttacgt
     3901 caaaattcac gtcatacaca ccaaccgttg caccggtttt ctttaaaatc tccgttttcg
     3961 gctggtgatc attcatcata tctaaagcgg cttgtgtctt tttaccaaat atctttgtta
     4021 aatgttttac ttctactttt accaaacaaa ttctcctttt ttatgtaaat tcatttttct
     4081 ttctgaaaaa agtgaccaca ctatgttaac atcatgtagt cactttgtca aaaatgaaag
     4141 aaatttgctt gtccaaactg aaaaaaactt ggctaaatct ttgtaaataa aaggtttagc
     4201 caagttaata tttttttaat atttcacaca atcattctgc aagctgatgc tccgggtaaa
     4261 aaaagtttgt catacgctgt agtgtatatt catttccaat aaaatgaacg atgtcccctg
     4321 ccgtaaattt agcatagggg ccaggtgaaa caagcagttc ttcattatga gaaattgcga
     4381 taactgtggc gccagtcgcc tgccagatat tcaactcgct aattgaacgg tccagatgca
     4441 ttgctttttc tgataaagat aattcaaacg gaagtaaagg attcatctta tgtattcgct
     4501 tcgtttgatt gaccagctga tccaataatt gagaaaaatg attcagctca tcttgttgct
     4561 tctccacact tgccatgatt tctgcttttg tatcttggat ggattgtaca tcttgatatt
     4621 gcaataggaa atcttttgct ttttccttcg aagcaacaaa tgccccactt ccatgccgta
     4681 cttccatgat tccaagatct accagcacat tgatagcctt gcgggtagtc tcaggagaag
     4741 cattgtacgt actggcaagt gttgagcggg catggatctt ctcacccact ttatatcggt
     4801 tttcaacgat acgttcggct aaatcaacag caatctgctg gtagcgcggg cggacgattt
     4861 ttttctttcc agacattttc tttcctcttt ctttttttac tttccctcat cttactatgc
     4921 tctagcaaaa taagcaaaaa aggggagaat agcctcttgc aacgactgat catcgcttga
     4981 tctgttcctt ttttactggg caagctgttt gacagtcatc acaattctta ccggatttta
     5041 aacgagtata gacaattgcg cctgcacttc caaagattaa cacacttaat aagaatgtcg
     5101 ccatcctatt cctctccttc taatgacaat atagtataaa actggttctt ggattttggc
     5161 tgacggaaca aaacataaac gagtcctatc atcagtaaaa tagcaagata cgtccctaac
     5221 gctacctgtc caccctccaa taagtgtccc aactgataaa tcacaaaact aactaaataa
     5281 gctaaaccgc attgatagcc tatggcgatc caagtccatt tcttggcatt catttcccga
     5341 tggatagccc caattgccgc aaaacaaggc gcacaaagta aattgaaggc taacaatgaa
     5401 taagctgctg cgggagtata tgtgtgttgt agcacttgcc agatttctct gccattttcg
     5461 gatacttccg catgaccaaa caaaatacca aatgtgccaa taatattttc tttagcgacc
     5521 aatcctgtaa tcgctgcgac tgttccttgc cagtttcccc aaccaagcgg ctgaaaaaca
     5581 actgccagga ttcgcccgaa aaaggctaag atactttggt cttcagaaac aggttgagca
     5641 taaaaattat aagaagagct gaaccagatc acgatactag aaacaaagat aatcgttcct
     5701 gcttttttaa caaaagactt gctgcggtca taggtttgtc ttaggaccgc tgaccattga
     5761 ggaaaatgat atgcgggcaa ttccatgata aaaggagctg tatctccagc aaacaaacgt
     5821 gtttttttca agctgattcc agagaaaata attgcagtca taccaagaaa ataggcagaa
     5881 ggagctaccc aagattgatg aggaaaaaag gcccctgcta ctaaggcaat aatcggcaac
     5941 tttgcagaac aaggcatgaa ggttgtgacc atgatcgtca aacgacgatc ttgctcgttt
     6001 tcaatcgtgc gactggccat gacgcctggc actccacatc ctgtagcaat cagcatagga
     6061 atgaaggatt ttcctgaaag accgaatttc ctgaaaagtc gatccatgac aaaagcgatc
     6121 ctcgccatat atccgcagtc ttccagaaag ctcaagcata aaaacaatat aatcaattgc
     6181 ggtagaaatc ctaacactgc tcccacgcct gcgatgatgc cgttcaagat cagctcctgc
     6241 atccatcccg ctacttgcca ttcagctaac aatctgccaa catgttctgg taaccatgta
     6301 ccaaacaatg tgtcattgat ccaatctgtc cccattgttc ctactgtttg aatagccaga
     6361 taatagatca gccacatcac aaatgcgaag atcggcaagg ctaaccaacg attcgttgca
     6421 atctgatcga ttttgtcact catcgataat tggaaagaat catttgacac aacacagagt
     6481 gtacatagtt gggtaataaa ttcataacgt tcattgacca gaatcgtctc actatcgtcg
     6541 tccaatagtt tctctgttaa ctggatcagt tgctcgatct ctttttgctg agaaactgct
     6601 atctcgtaat cctctcttac cttctgatct cgttcaaaat atttcattgc ataccagcgt
     6661 ttcttgccgc tttgttctcc tagtacatct tcaatttcat gtaaagctgc ttctaaacgt
     6721 ggatcatatg tacagggaac aggaatagaa ggccgctttt ttgcagactc ctgaatcttt
     6781 tcgattagtt tttcgattcc ttgctttttc aatacgctga ttggtaaaac tggtacacca
     6841 agaccatagg aaagcttttc tagattgatt ttttttcctt cttttttgat gacatccatc
     6901 atattcagac caatgatcat aggaatgtct aaatccaata actgcgtagt taaataaaga
     6961 tttcgttcta aattggtagc atcaataatg ttgatgatca gttcaggctg ttcctgaacc
     7021 aaataatctc ttgcaatcac ttcttctggt gtataaggag acaaagaata gatgccgggt
     7081 aggtcctgaa tatgaatgtt cggatttttt ttcaacgatc cttctttttt ttctactgtt
     7141 acgcccggcc aattccctac atattgattc gaaccagtca agagattgaa caagctagtt
     7201 ttcccgctgt ttggatttcc gactaacgcg atattcattc tttttcctcc ctttgtatca
     7261 agattagttc ggcctctgac tttcgtaacg tcagttcata ccctcgcact gtcagttcga
     7321 ttggatctcc cagaggggct agttttcgga taactatttt tacatttcgc gtcaatccca
     7381 tatccattaa ccgtcgcttc actgcgcctt gtccgtggat tgctacgacg atcccagtct
     7441 ctcctgcttt taattgatca agagaagtcc agctttcaga ggaagcagtc tttttattga
     7501 caaagatttg acctagtatt tcccgactta ctgccactcg atgacttttt accagtaaaa
     7561 tggcattgtt gcctgataaa ttgacgacga cgattttact tccggcaacg atcccgatat
     7621 tttgcaaatg gcgttttgtt ttttcttctg tttcgattcg ttcgacttga taaacgaaat
     7681 tctgctttgc ctgcgctaag gtctgcatat tgattcctct cttgtgaaat aaatcatgta
     7741 ttaaaatcat tcattatatg ttctaatttt cttacgtgtt acgcaaataa atgagaatca
     7801 ttctcacata gaatactctc ggtaattgag aatgtcaatt atacttgtga tattatgagc
     7861 gaatctttag tattgataga taaaaatgag aaaaaaatat ttcttcatag ttttccacaa
     7921 ttttttctct attaaatttg ctattttccc acacgatact tgttttcagc tcttttttca
     7981 aaaacacaaa acttagtatt ccacagtttc cacaacacaa tatgtagtgt ttgttgtttg
     8041 acttttttac taagagtttt atactatcta ttatagataa taagaatgtg ttagaggagg
     8101 cactcaccat gaacgtaaaa atcttttcta aaaataattg tatgcaatgt aagatggtca
     8161 aacggttttt aacagaaaat caaattgctt ttgaagaagt caatatcgat gaacagcctg
     8221 aagcagtaga ctggttgaaa gcacaaggat tccaaagtgt tcctgtcatt acttctgatg
     8281 cagaaacagt tatcggattc cgtcctgatc agttgcgtaa acttgccagc taacatgact
     8341 aaaagaatca aaacgtgata catggatttg aagggcttga gacagcacca gtttttgtcg
     8401 caaacttcca aatccttttt taaagcttaa aaacaatgca atgatttgca atcaagcatc
     8461 atcaaatacg aaatgaaggt tgggcgtacg tatgagtctt aaaaatttac aagatgtcag
     8521 ttatttcaag ctgaataatg aaatcaatcg gccagtcaat ggtcaaatcc ctttgaataa
     8581 ggataaagaa gctttagttg ccttttttga ggaaaatgtc aaaccaaata cgatgacttt
     8641 tccatctatt atggaaaaaa tcaattactt gatcgatcaa gaatatatag aagcagaatt
     8701 cattcaattg tattcaccat catttattga aaagctatat caatttttgg acgagcaaca
     8761 tttttctttc aaatctttta tggctgctta caaattttat tctcaatatg cgttgaaaac
     8821 caacgacggt tccgcttatc tggaaactta tgaagatcga gtagccttca attcgcttta
     8881 ctttgcgaac ggggatgaag aattagcact tgctcttgca gacgaaatga tccatcaacg
     8941 atatcagcca gctacacctt ctttcttgaa tgctggacgt aaacgtcggg gcgaattggt
     9001 gtcttgtttc ttgactcaag tcactgacga tatgaactct atcgggcgct caatcaactc
     9061 tgctttgcaa ttgtcccgta ttggtggcgg cgtagggatt actttatcaa atcttcgtga
     9121 agccggcgct cctatcaaag gatatgaggg tgctgcaagt ggtgtcgttc cagtcatgaa
     9181 attattcgaa gatagtttca gctattctaa tcaattaggt cagcgtcaag gagctggcgt
     9241 ggtttatttg aacgttttcc atccagacat tattgctttc ctttcagcaa aaaaagaaaa
     9301 tgcagatgaa aagattcgcg taaaaactct ttctcttggc gtgatcgtac ctgataaatt
     9361 ttatgaattg acacgtaaaa acgaagatat gtatttattt agtccatata gtgtcgaaaa
     9421 agaatatggt gtcccattct cttatgtaaa tattacagct gagtatgatc atctagttgc
     9481 aaatccaaac attcgcaaac aaaaaatcaa agcgcgtgat cttgaaaatg aaatctcaaa
     9541 attacaacaa gaatctggct atccttacgt aatcaatatt gatacagcga accgcgagaa
     9601 tccaatcgat ggcaagatca tcatgagtaa tttatgttca gagattttac aagttcaaac
     9661 gccttctgtg attaacggca aacaggaata tgaagtatta ggaacagata tctcatgtaa
     9721 cttaggctcg acaaatatcg tgaatttgat gcaaagccct aactttggtc aatctgtgcg
     9781 tacgatgact cgtgcattga catttattac agatgcatct gatatcgatg tcgtaccacc
     9841 gatccaaaac ggaaataagc tgaatcatac gattggatta ggtgccatgg gcttacacac
     9901 ttatcttgca aaagaacaaa tggaatatgg ctcagaggat tcattagact ttacaaatat
     9961 ttacttcatg ctgttgaatt attggacact tgttgaaagc aacaatatcg ctcgtgaaag
    10021 aaaacaagtt ttccataatt ttgaaaaatc agcttatgct gacggcactt atttcgaaaa
    10081 atacgtaact ggagaattcc agccaaaatc agaaaaagtc aaagcattgt ttgaaggcat
    10141 ttttatccca actgctgaag attggaatgc tttgaaacaa gcagtaatga aagatggact
    10201 gtatcatcaa aatcgcttgg cagtagcacc aaatggctca atttcatata tcaacgatac
    10261 gagtgcaagt attcatccta tcactcgcat gatcgaagaa cgccaagaga agaaaatcgg
    10321 taaaatttat tacccagcgc cttatctatc caatgagacg attccgtatt acacttctgc
    10381 ttatgatatg gacatgcgta aagtaatcga tgtttatgca acggcacaac aacacgtcga
    10441 tcaaggcatg agtttgactt tattcatgcg ttctgaaatc ccagaaggca tttatgaatg
    10501 gaagacaaca acgaagcaaa cgacacgtga tttgaatatt ttaagacatt acgctttcca
    10561 caaaggaatc aaatccattt attacgtacg tacctttact gatgatgcag aagaaatcgg
    10621 aagcaatcaa tgtgaaagct gcgtgatcta atatcataga tagattcgct tattcatatt
    10681 ttaattaaag gagcattctc atgtcagaaa catattatga agcaataaac tggaatgaaa
    10741 ttgaagatat cattgataaa tccacttggg agaagctgac agagcaattt tggctagata
    10801 cacgtatccc actttcaaat gacctagatg attggcgtac attgtctcaa ttggaaaaag
    10861 atacagtagg acatgtattt ggcggtttga cactgctaga tactgtccaa tctgaaagtg
    10921 gcatggatca gttgcgtaaa gatgtccgca ctccccatga agaagccgtt ttgaacaata
    10981 ttcaattcat ggaatccgtt catgccaaaa gttattcttc tatttttagt acactgaata
    11041 cgaaaaaaga aatcgaagaa atttttgact ggacaaatac gaatccttat ctgcaaaaaa
    11101 aagctgagcg tatcaatgaa atctacaaac acggtacacc gctagaaaag aaaattgcca
    11161 gcgtcttttt agaaacattc ttgttctatt caggttttta tactcctctt tattatttag
    11221 gaaacaacaa attggctaac gtagcagaga tcatcaaact aatcatccga gatgaatctg
    11281 tacatggaac ctacatcggt tacaaattcc aattaggatt caacgagtta cctgaagcag
    11341 aacaagaaac gttaaaagac tggatgtaca atcttcttta tgagctttac gaaaacgaag
    11401 aacgttatac agaagaatta tacgatccaa tcggctggac agaagaagtc aagacattcc
    11461 tacgctataa tgccaacaaa gcattgatga acctagggat ggatccactc tttccagata
    11521 ctgccaatga tgtcaaccca atcgtaatga acgggatttc aacaggcaca agcaaccatg
    11581 acttcttctc acaagtcgga aacggctatt tgttaggtca tgtagaagcg atgaaagacg
    11641 acgattattt gattggattg gaataaggat ttattttaat tcaaaaattt ttcgaaaaat
    11701 aaaaagagtt tagcgtacag atattttaaa tgtacactga actctttttt atgcttattc
    11761 acttgtttct tccagcactt ttggactgtc taacttttcc gaaacatgtt ccattcttct
    11821 caataaatag attttccgga tatttaatat tatcgtctta atcactgcat agacaggtat
    11881 gcaaatcagc atgcctaata ttcctgcgac acttcctgct ccaatcaata ccaagatgat
    11941 cgtcaaagga tggatattca ttgatttccc aaataacaac ggcttgatca aatttccatc
    12001 taattgttgg atcactaaaa tcgacaacgc catatacaaa gcttgaaatg gagagataaa
    12061 caaaccgaca atgattgctg gtaccgctcc aataaaaggg ccgacatacg ggataatatt
    12121 cgtgattccg caaatgaccg caagcaacaa gctataaggc tgatcgaata ttctcattgc
    12181 caaaaagctc attacaccaa taatcaaagc atctaagatc gtactgctga tataggcaga
    12241 taatgtttcg tttaattctt ttaccgtttg gcgtaactct ttacgaatcg ctttcggaaa
    12301 gaagtgagac aacgcatcaa taaatttgtg cccatccttg aacataaata gcaaaataaa
    12361 tggaacggta aataacaaaa taaaaaattg catcataaat gaaatgattt ttgagacact
    12421 tgcagataaa ctgactaata tgatattgaa caaattacta agagataaat ttgctgatgc
    12481 taattgttct tccaaattga aatttttaaa ctcttcccgc tgcgccaatt catttaacca
    12541 tttgcttgtt tcatctgcat acattggcaa gctctgggtc aattgaattg tctgttccat
    12601 taactgaggc actacattca tgacagttaa aacaactaaa atgattacga ccaaaaacgt
    12661 caataaaaaa ccgaacactc tcgggatccg atgcttttcg agaaaaacaa cgattggatc
    12721 gaacatataa tagataaaac cagcaacaag caatggtaaa aaaattgccg aaagcatttt
    12781 caatattgga ctaaaaatat tcggcatttg taaaataaag tacacgccga tgatcgtgag
    12841 tactagctcc actgtccaga aaaataattt tgattgttta aaacgtgatt gcatacatct
    12901 cctccaaggt cctttgatac ttctattcta tcatttaaca aagagttacg cgctgagatt
    12961 ttcatttgct taaaaaaaac aaaaaaaata aacatatttt aatgagtaga cgagtactta
    13021 aacaaaaaca cggtttggag tagtgacaaa aattatactg cagtcccttt ttccaaataa
    13081 acggtgttca aaagcttgca tcttcgtaat aagcccagcc aaacgaaaaa tataaggaac
    13141 tatttttatt tggctgggct tattacttga tgtaggacat ctattttaca acctcagatc
    13201 atttattgcg caatactgac taaatgcaac tttgtgatat ttttgtgtac ggacaactcc
    13261 tcgatcacat cggcataagt gagccctttt ggaagatcaa tcgtatagat atttttgtac
    13321 actcggtagt catcaacgaa ttttacgtca aaattcacat cttcgattac gatatttttc
    13381 tcttcaaaat aatcggtaag aaaatctttg gtttcttttc tatggataaa ttggatttct
    13441 aactttttag tcgtaggtac atggatcacg cgtttcacta ctgtgagtgc aatagcaatc
    13501 ccgataaaac tgatgatcgc aatggaatag taacccatgc cgatggcgat ccctaatcca
    13561 gcaattgccc ataaagaagc ggcagtcgta agtcccgtca ccgattgttt cgtgacgatg
    13621 atcgttcccg cgcctaagaa accgacacca ctcaccactt gagcaatcag ccttgcttca
    13681 tctgaacgaa tcgttccagc aagctgtgga tactctaaag catctcttaa tgcaccacta
    13741 gcgatctcaa cttggatcaa tgcaatgata catgctccca tacaaactaa aatatgcgta
    13801 cgcatacctg ctggacgatt tttatattgt cgttcaaaac cgattgctcc gccaaatagc
    13861 atagcgatcc ctaaacgtaa aataatctct ggaattgtca ataccatatc attcatctaa
    13921 acaccctcca gtccaatata tcatgtctga aaggagcaga caaaaaaagt gcaattttta
    13981 cctcttacga aaaaaggact gtgacaaaat ttttgtcata gtccttttta tgaataaacg
    14041 gtgttcaatc agctgaccct cggtattact caacaaacgg caaaatatgg ggagctattt
    14101 ttcctttgtc ttctctaata ctcaggtcaa aacgctgatt tcacaacctc tttagcctac
    14161 tattgaaaat tacaacttac ttgctgcttc ttcatcgatg atcacaacaa cattgtcgtg
    14221 attttgcaat acacttgctg gcaaatgatt cgttacaggt ccttcaatca tccctttgat
    14281 tgcatcagct ttgctttcgc caaatgccat caagacgatt tctttacttt tcataattga
    14341 accgattccc attgaaacag cttttgttgg tacatcttct gctttatcga agaatcgttt
    14401 gtttgcattg attgttgatt ctgttaagtc aactactgaa gtcgttccgt caaatgaagc
    14461 accaggttca ttgaaaccga tatgtccatt ttgcccgatt cctaagattt ggatatcgat
    14521 tggatgtgca tcgatgattt gatcatactt tttgcatgct gcttccagat cttctgcttt
    14581 tccatctggt acaaacgttt ctttgaatgg ttttttatca aataattgga catccatgaa
    14641 atgacggtag ctttgttcat ctgaaccgcc tagtccaacg tactcatcta agtttacaga
    14701 agtcatttca ctgaaatcca aatcgcttga agtcatttct ttatataaag taactggtgt
    14761 gcttcctgtt gccaatccta atacttttgc acctttgttc ataccttctt tgatgatttc
    14821 aaatgctttt tttccgcctt cttcagcgtt ttttacacga atgatttcca tagtgattgc
    14881 tcctttatat tttggtatag cccaattata gcattctttt tttcttttta caataattag
    14941 tatagaccaa attgcatttt tttcattttc ttgacaataa ataggaatcc gtgttaggtt
    15001 tcataagatg gttcaatcaa acaatccatg ttgcatgaaa accaagcaag tgattcactg
    15061 tggacgcttt atgtctgcag tttttttatg aaaaaggagt tattatgagt atactgacat
    15121 taaacaacat tacccagcaa tttggcgaca aaatcctcta tgaaggtgtc gatctgcaat
    15181 taaatgctgg cgaacatctt gggctgattg gacaaaacgg agccggtaaa agtacattga
    15241 ttaaaatcat cactggtgag atcttaccag atgacggaca gatccattgg caaaaaaata
    15301 ttcacaaagg ttacctcgat caatatgtgg aagtcgatga aacattaaca atcgaagaat
    15361 ttctaaaaac tgcgtacgca aaagaatacg aaaaggaaga aaaaattgct tttctttacc
    15421 aaacatatag cgagaccttc gatgattcct tgctggaaaa agctgggaaa ctccaaacgg
    15481 aattagacca aggagtgttt tatcaaatcg acaccttagt tgctgagatg agcagcgggt
    15541 tggggatcga tgtcttaggt ttagattcac tgttgaaaaa tctaagtggt ggacaacgtt
    15601 caaaggtgat tttagcaaaa ctacttttag aaaacccaga tgttctgatc ttagatgaac
    15661 caaccaatca cttagatgat cagcatatcc aatggctgac gcagtttctt caggattttg
    15721 acggtgcgta tatcgtgatt tcccatgacc aagaatttct tgatcagatc accacccata
    15781 tcgcagacat cgagtttgga aagattacta agtatactgg ccatctaaaa caagcattga
    15841 aacaaaagga acaaaatcgc gaaagctatt tgcgccaata tcatgctcaa caaaaacaaa
    15901 tcgaaaagac cgaagcttat attcgaaaat acaaagccgg ttcccgatca acgatggcaa
    15961 aaagccgaca aaaacaatta gataaaatcg aacggctgac gcctccagct tcagcaagta
    16021 aagctgtctt tgattttcca ttctcgccta ttgtcacgac attagcagtg gaaacaactg
    16081 atttagtcat cggatatgat cgaccgctac ttgcacccat caatttgacc atccgctttg
    16141 gtgaaaatat tgccattcga ggcttcaacg ggattggaaa atctacttta ttaaaaacac
    16201 tgatcggtga gattgaaaaa ataagtggcg atttccactt cccagataac acaaaaatca
    16261 attacttttc acaagatctg tactgggaaa atccattaga aacaccacta caatatttaa
    16321 gcagtcaatt tccaaaagcg actatcaaag aattacgtcg ccaactagct aaagcagggt
    16381 tagttaatca attagcaagt gaacctctca ctacattaag tggtggggaa caaactaagg
    16441 tgaaacttgc acagttgaca atgaaccaag gtaatttact gattctcgat gaaccgacga
    16501 accatatcga tcaagaaacg aaagaaagct tacaagacgg gatacagaaa tttccaggaa
    16561 cagtaatcat cgtctctcat gaacaagaat tttatcaaga tcttgtgcaa cgagtcattg
    16621 agattgaacc aaaataaacg tttgattgaa tagttgaaaa aaaggagctg tgacaaaagt
    16681 tttgtcacaa ctccttcttc tgaataaatg gtggccaatt agctgacctt cggtattagc
    16741 tcaaaaaacg gcaaaatatg aggagctatt tttatttggc tattcttatt acttgatgca
    16801 gaacagcttt tcacaacctc ttttcgtcta ttttttattt tcgagatttc tctttccttt
    16861 aaaaacaact gtttgaaaga agaacgcaca tccttgaaaa acaagcccgc taaccgttac
    16921 acctaaccag ccatactgct gccacattgt cgtccctagc aatgaaccag ccgcacctcc
    16981 aataaagtac ataaacataa ataca
//
LOCUS       DAFEKH010000059        16866 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.062, whole genome shotgun sequence.
ACCESSION   DAFEKH010000059
VERSION     DAFEKH010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16866
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.062"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            203..1144
                     /locus_tag="LP386_002284"
     CDS             203..1144
                     /locus_tag="LP386_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HBL1919496.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            1213..1944
                     /locus_tag="LP386_002285"
     CDS             1213..1944
                     /locus_tag="LP386_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HBL1919497.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            2088..4268
                     /locus_tag="LP386_002286"
     CDS             2088..4268
                     /locus_tag="LP386_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HBL1919498.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            4288..4800
                     /locus_tag="LP386_002287"
     CDS             4288..4800
                     /locus_tag="LP386_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HBL1919499.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVLEDVMEKSNGLRQKEKTLMKHKKSDERIE
                     GLWKKVSRGI"
     gene            4773..5534
                     /locus_tag="LP386_002288"
     CDS             4773..5534
                     /locus_tag="LP386_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBL1919500.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            5665..6999
                     /locus_tag="LP386_002289"
     CDS             5665..6999
                     /locus_tag="LP386_002289"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HBL1919501.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            7306..7791
                     /locus_tag="LP386_002290"
     CDS             7306..7791
                     /locus_tag="LP386_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HBL1919502.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            7784..8467
                     /locus_tag="LP386_002291"
     CDS             7784..8467
                     /locus_tag="LP386_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HBL1919503.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            8593..11238
                     /gene="polA"
                     /locus_tag="LP386_002292"
     CDS             8593..11238
                     /gene="polA"
                     /locus_tag="LP386_002292"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HBL1919504.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELADKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            11283..12119
                     /gene="mutM"
                     /locus_tag="LP386_002293"
     CDS             11283..12119
                     /gene="mutM"
                     /locus_tag="LP386_002293"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HBL1919505.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            12083..12712
                     /locus_tag="LP386_002294"
     CDS             12083..12712
                     /locus_tag="LP386_002294"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HBL1919506.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            12764..13096
                     /locus_tag="LP386_002295"
     CDS             12764..13096
                     /locus_tag="LP386_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBL1919507.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHISDEQKIEEQRMKH
                     YTGIEEKL"
     gene            13408..13899
                     /gene="nrdR"
                     /locus_tag="LP386_002296"
     CDS             13408..13899
                     /gene="nrdR"
                     /locus_tag="LP386_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HBL1919508.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            13922..15295
                     /locus_tag="LP386_002297"
     CDS             13922..15295
                     /locus_tag="LP386_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBL1919509.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            15295..16221
                     /gene="dnaI"
                     /locus_tag="LP386_002298"
     CDS             15295..16221
                     /gene="dnaI"
                     /locus_tag="LP386_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HBL1919510.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            16350..16790
                     /locus_tag="LP386_002299"
     CDS             16350..16790
                     /locus_tag="LP386_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBL1919511.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
BASE COUNT         5759 a         2954 c         3715 g         4438 t
ORIGIN      
        1 atgttggtga agttcaccaa catcaaaaag tatagagccg tttttctgtg cgaaacagga
       61 aagcgaagtc tttttaattc aaataataat attatgtaaa caaaaaactt tccatgcgta
      121 attatacaca agcaaataaa tcgtcaaatg cgaacgcctt ctttatactg tttaggaacg
      181 aaaagaagga aggaagaaat acatggatta tcaagtactg ctttattaca attatacaaa
      241 aatcgaagaa ccagaggaat ttgccaaaaa tcatttagcc ttttgcaaat ctttggatct
      301 taaaggtcgt attctagtag ctgaagaagg aataaatggt actgtgtctg gaaccgttga
      361 aaacacgact gcctatatga aagcaatgaa agctgatcct cgatttgctg atacgatgtt
      421 caagatcgat ccaagcgaag gacatgcctt taagaagatg tttgtaagat accgtccaga
      481 gcttgtaagt ttaaagctag aagaggacat tgatccaaac caagtgacag gtgcctatct
      541 ttcaccgcaa gaatttaaag aagctatttt agatgaacag acagtggtga ttgatgcacg
      601 gaatgattat gaatatgact tgggacattt tcgaggggct gtacgcccag atatacgcag
      661 ttttcgagag cttccagact ggatccgcga gcacaaagaa gaatttatgg aaaaacgggt
      721 agtgacctac tgtactggtg gcattcgttg cgagaagttt tctggttggc ttgtccgtga
      781 aggattcaaa gatgtcggac agctgcatgg cggtattgct acttatggta aggatcctga
      841 agtccaagga gaattatggg acggcaagat gtatgtgttt gatgaacgga tcgctgtcga
      901 tatcaaccaa gtagataaac aaatcgtcgg tcgcgactgg tttgacggaa caccatgtga
      961 acgatatatc aattgtagca atcctgagtg caatcgtcag attcttgctt ccattgaaaa
     1021 tgaagaaaaa catttaggag catgtagcat agagtgtgcg aaacatccgc gcaatcgcta
     1081 tgttcaagac catggaatct ctccagaaga agcagaactg cggtttacag ctttaattaa
     1141 atagaaaaca atagttttga ttgtcgacca tttccaatat gcgctatact agcgttgagg
     1201 atggtgatcc acatgaaatc attgatttat gctattgggg atgtccatgg caaacatgag
     1261 ctttttgaaa aacttattca ctattatgat ccaaagatcc atcagcttgt tttattaggg
     1321 gatctcaatg atcgaggtcc tcgtacaaaa gaatgttttt tattaggaaa gcaattagtc
     1381 gaagaaacag gagccattta cctccgggga aaccatgaag aatatttttt gcaatttctg
     1441 caatcaccgg aggactggta tgcgccttat atgagaaatg gtggaaaaga aacgtttgaa
     1501 agcctgattc acccaggggc atcggaggaa tactccccaa ctgaaatctc gatgatgatc
     1561 caatcgagat attcagaact gattaaattt ttagtccagc gccccttgta ttatgaatgg
     1621 gaaaattatc tttttgtcca tgccggtgtg gatttgacaa agaaagactg gcgtaagaca
     1681 agtctaagag actttatttg gataagggaa ccatttcatg aagggaaaaa caatacaggt
     1741 aagacaattg tatttggaca tacgattaca ccaatgctcc atggagatat gcagacaaca
     1801 gacctctgga ttcaggatca taaaatcgga atggacggtg gggctgtatt cggagggtca
     1861 ttgcatgggg ttgtttttga caaggaaggt attcttcaag atattgaata tcagaacaac
     1921 gaaggacctt ggcatggaat ctgactaatg gaaagaatga aggagctgtg actttgttgc
     1981 ggctcttttt atttttatag agaatattgt ttctttcagt agtttaaccc aggataaaaa
     2041 gtatgataga ataaagaagc aatttttagc agaaaagagg cattttaatg acggaaaatt
     2101 tgaaccagac gatcattcag cttgtacaaa aagaactttc agactatcgt cctaagcagt
     2161 tgactactgt acttaatttg ttaaatgaag gaaacactgt tccttttatc gcgcgttacc
     2221 gaaaagaaat gactggaagt cttgatgaag tccagattcg tgaaatcgaa gagcggtatg
     2281 cctatcttga aaacttagaa aaacgtaaaa ctgaagtgat tcggctaatc gatgaacaag
     2341 ggaaactgac tcccgagtta gaagcagaaa tcacccaagc cgtgaaaatg caacaagtgg
     2401 aagatttgta tcgtccatac aaacaaaaac gacggacaaa agcaacgatt gctaaagaaa
     2461 aaggacttga accactcgcg aagtggctga tgcagcttac agatggagag gtgcaatctg
     2521 aagcagaaaa atatattgac aaagaaaaag aagtctcttc tgccgaagaa gcgttgcacg
     2581 gtgctcatga gattattgct gaacaagtca gcgataatgc aaaatttcgg acttggattc
     2641 ggtcttatac gtataacaaa ggtatgtatg tcagcaatgt caaggatgag caagcagatg
     2701 aaaaaggcgt atatgaaatg tattatgact ttgcagaacc cgtccataaa atggtttctc
     2761 atcgaatatt agctactaat cgtggagaaa aagaagatat tctgaaagta ttctttcaag
     2821 tagatgaagc agcaatttta gcttacttgg atcgccaaat agtcaaaaat cctgcctctc
     2881 cttcttcttc attcgtcaga gaagcctatc aggatagtta taaacgcttt attcagccag
     2941 caatcgagcg agaactgcgc aatgaattga ctgaaaaggc agatgagcaa gcaatcgcta
     3001 ttttcggcga aaacctccgt aatcttttgt tgcaaccgcc actaaaaggt aaagttgtcc
     3061 tgggatttga tccggcttat cgtactggat gtaaactagc agtcgtagat gcgacaggga
     3121 aagttttagc aatcgaagtt atttatcctc ataaacctgc agcgcaagca aaaagagaag
     3181 ctgctggacc agcttttatc caattaatta ataaatatca agtagatatg gtagctatcg
     3241 gaaatggtac agccagtcgg gaatctgaac tttttgtggc tgagcagttg aaatccgccg
     3301 accataaaac ctattacgct atcgtcaacg aagcaggcgc ttctgtttac tccgctagcg
     3361 aaattgcacg aaaagaattt ccgcatctac aagttgaaga aagaagtgct gtttctattg
     3421 cccgtcgcct gcaagatcct ttagctgaat tagtcaaaat cgatcctaaa gctgtcggag
     3481 taggccagta ccaacatgac gtttctcaaa aacgtttggc tgaacaattg gattttgttg
     3541 tggaaacagc ggttaaccaa gtaggtgtgg atgtgaatac agcaagcccg cagctcttgc
     3601 agcatatatc aggattgaat aaaacaactg cccaaaacat tgtcatttat cgtgaagaaa
     3661 acggagaatt caccgcacga actcaattga aaaaagtgcc acgcttagga ccaaaagcat
     3721 atgaacaagc aatcggattc ttgcgagtcc ctggtgggaa aaacattttg gacaacacag
     3781 gtatccatcc cgaaagttat tctattgcaa aagaaatatt aacttcagtc caactttcag
     3841 aaaaagagct tggtacagaa gaagcagtag aaaaattgac acgattatcc gtagagaaac
     3901 tggctgaaag cctatcagtc ggagaagaaa cgttagccga tattttagct gggctgacac
     3961 aacctggacg agatatgcgt gatgagatgc cagcgccctt attacgtaca gatgtattga
     4021 gtatggaaga cttgaaacca gggatggaat tgactggaac ggtccgtaat gtcattgact
     4081 tcggcgcatt tgttgatatc ggtgtgaagc aagacggact tgtccatata tcgaaactca
     4141 gcaaaaaatt cgtcaagcat cctacagatg tcgtgtcagt aggagatatc gtaacagttt
     4201 ggatagaaca agtcgatacg aaaaaaggca gaatcagttt gacgatgctt tccccttatg
     4261 aagagtaaca atgaggagta acaaaaattg acacaagaag aactgcagca gttagtagaa
     4321 gagatatcat taaaaagctt ccagcttcct ttcaagcacc aagcaatgtt caatccacgc
     4381 ttacgtacaa ctggcgggcg ctatcattta aacgatcatc atttagattt taatgcgaag
     4441 ctatttgaag agtcagacga agagacgatt gcaggaatca tcaaacatga actttgccat
     4501 tatcatcttc atctagctgg aagagggtat cagcataaag atatggattt caagtatctt
     4561 ttgaaaaaaa caggagggtt gcgctatgca ccagccttga cgaagaaaca gataaagatg
     4621 gagtattatc gatgccaaga ttgttctgcc acgatctgcc gcaagagaag aatcgatgta
     4681 ctggaagatg tcatggagaa atcaaatgga ttgagacaaa aagagaagac tttaatgaag
     4741 cacaaaaaat cagatgaaag gatagaaggc ctttggaaaa aagtgagcag aggaatctaa
     4801 aagactggaa tcagctatta aattttttag ccgcacctga agagggaaat tttgaggaac
     4861 tgacggcacc tacacttatt ttagctggaa actgtcttcc tatcttagct gataaagcag
     4921 cacaaatgta tttaaatggc caagtagatc aattgttttt ggtcggaggg gtggggcatg
     4981 cgactagaat cctttatgag aattttgaaa agcaaggatt tcattttgaa gatggcatga
     5041 gtgaaagtga aatctgtcgt cagtatctaa aagaagtcta tgatttgccc gataaggctt
     5101 ttctgataga atcgaagtct acaaattctg gagagaacgc cactttttca ctggagattc
     5161 ttcattcctt aggagctgta ccagaaaaaa tcttattgat gaatgatccg acactgcaac
     5221 gcaggactcg agcaactttt gagaaagtat ggcaaaatga acaaactatt ttcgcgaatg
     5281 ctgtgccatt tgtgccggaa atccttcact tttctgaaga gatcatcttt acagcaaaag
     5341 aactgaatca tcaatggcct aaggaatatt tccatgcgct agtattagga gaaatggaac
     5401 gtctccatga cgatgagaac ggctatggtc cgaaaggaaa agattttatt cctcacattg
     5461 atatatcaga ggaagtttgg tcttcttaca ccagaattaa agagtcaata aaaacggatt
     5521 tttctcgtac ttgaccattt tagcaagcga atcctccttt ccaaataaat ttggttgaaa
     5581 ttttcaatcg tttataagat aatgaggagc gtgttgaatg taatagctaa aagaatggac
     5641 gctagataag agaagaggat tcaaatggaa aatcaaaata aattgtatca ttttgttggt
     5701 atcaaaggtt caggaatgag ctccttggct cttgttttac atgaacaagg tctaaatgtc
     5761 caaggatcag acattgaaaa atatttcttt acacaaagag atttagaaaa agcaaatatc
     5821 acgattctgc catttaacgc agataatgta aaaccaggga tgacgatcat tgcaggaaat
     5881 gcatttcctg attcacatga agaaatccag cgagcaaaag aattaggttt ggaagtgatt
     5941 cgctatcacg actttattgg tcattttatc caaaattata cgagtatcgc tgtaacaggc
     6001 tctcacggaa aaacaagtac gactggactg ctctctcatg tattgagtgg tgtccgtcca
     6061 acaagttatc taattggaga tggaacagga catggtgatc cgcaagcgga attcttttca
     6121 tttgaggcct gtgaatatcg ccgtcatttc cttgcctatt caccagacta tgcaatcatg
     6181 accaatatcg attttgatca tccggattat tatacaagta tcgacgatgt atttacagct
     6241 ttccaaacaa tggctggaca agtgaaaaaa gctatttttg cgtatggtga cgatgcttat
     6301 ttacgcaaat taaaagcaaa tgtgccgatt tattattatg gtgtcacaga aaacgatgat
     6361 atccaagcac gaaacatcga acgcacaact tctggttctg cttttgatgt ctatcatggg
     6421 gatgaatttg ttgggcactt cactgtacca gcattcggta aacacaatat cttaaatgct
     6481 ttaggtgtta ttgcagtagc ttatttcgaa aaactggatc tgaaagaagt tgcagaagaa
     6541 atgctgactt tcccaggagt aaaacgtcga ttcagtgaaa agatcgtagc agacatgacc
     6601 gtagtcgatg attatgcgca tcaccctgca gagatcaaag caacgattga tggcgcacgc
     6661 caaaaatatc cagataaaga aataattgca gttttccaac cccatacgtt tacgcgtacg
     6721 attgcattga tggatgaatt tgcagaagca cttgatttag ctgataaagt ttacttatgc
     6781 gatatttttg gttcggctcg ggaagaacaa ggaaacgtta agattgaaga ccttggagcg
     6841 aaaatcaaaa aaggtggaga agtcatcaaa gaaaataatg tatctccatt gttagattat
     6901 catgatgcag tagtaatctt catgggtgct ggagatgttc aaaaatttga acaagcgtat
     6961 gaaaaacttt taagcagcac gacgaaaaat gtactgtaat acaattactg cagtgtcctt
     7021 ataaaaatag aaagaggggg agtggcaaaa atcttgccaa gccccctttt ttgcaactta
     7081 tgataaacgg tgttcaaaag cttgcatctg cggtaataag cccaatcaaa tcaaaaacat
     7141 gagaagctgt tttttcttgg ctgttcttat tatttgatgc aggacagctt tttcacgacc
     7201 tctgtaaact ataggaatct gttaaatcaa gggagcagaa cttgcctttt acgctacttt
     7261 tggtacaata atgtatgatt aaaaataaac tggagggttt ctatcttgaa cataggtaag
     7321 ccgagaaaac taggaaaaac aataaatgaa atcgaggaag gcgactcgtt atccttaaca
     7381 gaatctattg aagataacca gcttttgctg tatttgggat tgacgaatga tgcaaatcct
     7441 ttgtatatcc aacatgactt tgcacaaaaa acagaatatc aacagccaat cgttccatca
     7501 gtgatgctga tggggatcat cacaagtgca atttcaaagc atcttcctgg accaggatca
     7561 catgttgtca atttttctgt caattttatt gaaccggttt tccattatga aacactgact
     7621 tttcagtttg aggtcataaa agtagataag atgaaggatg tggtgacgat ttctgtagaa
     7681 gcggagaata cgaacgaaga tcgtgtgttg gatgctgtcg ttatggtcca accgccacaa
     7741 gttcctgaat tggaaatagc aatcgaaagt gaaggtgaat tgaatgaata atccaagtac
     7801 atcaatgtca ggtatcaatc gtttttatgc aaaagtttat ggatttttag gtatgggact
     7861 tgcccttagt gcagtcactt cttacttggc tctttgggta tttcctttgc aattagcaac
     7921 ttttatcaat aattttccac taggctttgt gggtctgtgg atcgttgaac tgattttagt
     7981 aatggttcta ggcgtaaaag cacaaaagaa tccgagctta gcaatcggtg gatttattgc
     8041 ctactctctt ttgaatggca taacattagc ggttactctt gcatactacg atattggaac
     8101 agtaacgcaa gctttcttga cagctacttt gatgttcatg gggatgtctg ttgtcggagt
     8161 aacaacaaaa agagatctta gcggggttgg aagagcagga caggcagctt taatcggagt
     8221 gatcattgca ctagtcttga acatcttcat tttgagaagt agcgtagttg agctgttcat
     8281 ctccctactg ttagtcgtca tctttgcagg gattacagct tatgataacc aaagcatccg
     8341 taatatctat gtccagacaa acggaacagc acatagtgga attgctgtat tcatggcatt
     8401 gaagctgtat ttggacttta tcaacttgtt cttggcgttt ctgagaatct ttggacggaa
     8461 caactaaaaa agaaaaaaat tcatcagttg gggctatacc gaattatttg gtatggtccc
     8521 gctttttctt ttcgcattcc gcaggattct ttgttagaat gaataagaac tttacagtaa
     8581 ggagttaaga agatgacaaa aaataaatta ttactcgttg atgggaacag tgtggctttt
     8641 cgcgcattct ttgcgcttca caattctctt gaacgtttca aaaatagaaa cggtcttcat
     8701 acaaatgcaa tctatgcatt caatacgatg tttgaaaatg ttatgcaaaa agagcaaccg
     8761 actcatgttc tggttgcgtt cgatgcagga aaaacgactt ttcggacaga aatgtatgcg
     8821 gagtacaaag gtggaagatc caaaacacct ggcgaattca aagaacaaat gccatatata
     8881 cgtgatttgt tgacaggact aggggtacag tattacgaat tgcccaatta tgaagcagat
     8941 gatattatcg gtactttggc agaaaaagta gacaaagatc aatttgatgt cgtcgtgctt
     9001 tcaggtgatc gggatttgac tcaattagct agtaaagaag taaaagtgga tatcactgta
     9061 aaaggtgtca gcgatatcga aagctataca ccagaacatg tagcggaaaa atatgatggg
     9121 ttgacgccaa aacagattat tgacatgaag ggactagccg gagatgcctc tgacaatatc
     9181 cccggtgtga ctaaaatcgg tgaaaaaaca gctatcaagc tattgaaaca atatggctca
     9241 gtcgaaggaa tttatgaaca tatcgatgaa atgaagcaaa gcaaaatgaa agaaaatctg
     9301 ataaatgaca aagagcaggc tttcttatcg aaaaaattgg cgaccatcaa tacttcagcg
     9361 cctgtggatg tctctatcga ctcattgaag tatgaaggga aaaatctcga taaactcgtt
     9421 ccgttttata aagaaatgga tttcaatcag ttcctttcta aattgaatat cgtagaagaa
     9481 gaagtaaaaa tggatgatat tttgtttgaa gtcgttcatg aattcaaaga ggaaatgttt
     9541 actacggata tggcgttgta cgtggaaatg atgggcgaca attatcatac agaggaaatc
     9601 gtcggagtag cgtgggggac agaaaagaaa atttatgtca cgaacgatct atctgtattc
     9661 gaaaaccgag cgttccattc ttggatcact gatccgactc ggctgaaaaa agtatatgat
     9721 gcgaaacgaa cttatgttgc tttaaaccgc tatactggaa aaacgaaagg aatcgatttt
     9781 gatgtcttgc taggtgcata ccttctcgat acgaatgaaa aaagcacaga tatcgaagga
     9841 atagctgctc attacggata caacgatatc caatcagatg aagctgtata cggcaaaggg
     9901 gcgaaaaaag gtttaccaga agaagaggaa ctcttttttg ctcatttagc gcgaaaagta
     9961 gctgcaatca atgcgttgac accaaaattg agccaagaac tggcagataa aaaccaagaa
    10021 gatcttttcc ggaaaatgga actgccattg tctatcattt tggcagagat ggaaataagc
    10081 gggatcaaag tagatgcgac tcgcttacaa gaaatgaagg gcgagttctc tgctcgctta
    10141 agagagatcg aacaaaaaat ctacgaagaa gccggcgaag aattcaattt gaattcacca
    10201 aagcaattag gagtgatctt atttgaaaaa atgggattac ccgttatcaa aaaaacaaaa
    10261 actggatatt ccacagccgt agatgtactg gaacagcttc gtgaacaagc accaatcgta
    10321 gaggatatcc tcacctatcg tcaaattgca aaaattcaat ctacctatgt cgagggactg
    10381 ctgaaagtga tccaatcaga tggaaaagtg catacccgtt atgtccagac attgacccaa
    10441 acaggacgat taagctctgt tgatcctaat ttgcagaaca tcccgattcg attagatgaa
    10501 gggagaaaga tacgtcaggc atttgttcct agagaaaaag actggctgat ttattcttct
    10561 gactattcac aaatcgagtt acgcgtactt gcgcatatct caaatgatga acatttgaaa
    10621 gctgccttcc tagaaggtca agatatccat gccagcacag cgatgcgtgt atttggaatc
    10681 gaaaaggcag aggatgtcac accaaatatg cgtaggcagg caaaagcagt gaattttggt
    10741 atcgtgtatg gcatctctga ttacggactt tcacaaaatc taggaatcag ccgaaaagca
    10801 gcacagcaat acatcgatac gtactttgaa aaatacccag gtgtcaaaga atatatggaa
    10861 agaatcgtac gcgaagcaaa agaccaaggc tacgtcgaaa cgctgtatca ccgccgtcga
    10921 tatctgccag acatcaattc aagaaattac aatatccgtt cttttgcgga acgaacagct
    10981 atcaatacac caatccaagg aagtgctgct gatattttga aaatcgcgat gatcgaattg
    11041 gataaacgat taaaagaaac aggtcttcaa gctacgatgc tgttacaagt tcatgatgaa
    11101 cttgtcttcg aggtaccgga aaaagaactt gaatcattag ataaattggt gaaggaagtt
    11161 atggaacaag ctgtttctct tcatgtacca ctgatcactg acagcagttg gggaaaaacg
    11221 tggtacgaag caaaataaac attgtttaag acagagcaat ataatgaagg tgaaaagaaa
    11281 aaatgccaga attaccagaa gtagaaaccg ttcgtaaagg attggaacgg ttagtagtag
    11341 gaaaaacgat tcaaaaagtt caggtcttgt ggcccaagat catcgagcaa ccagagacac
    11401 ccatctttga ggcttctctt gttggcgaaa ccatccaatc cattggacgt agagggaagt
    11461 ttttaatttt tcatctcgat cattgtgaac tgatctcaca cttgcgaatg gaaggaaaat
    11521 atcaatttac gaaagaaaat acaccaatcg ataaacatac gcatgtactt ttcttttttg
    11581 aggatggaag ccaacttcgc tacaacgatg tacgaaaatt tggtcgtatg acaatcgtcg
    11641 aaaaaggagc aagtgcaact taccgaggaa tcatgaaatt gggacctgag cctttgccag
    11701 atagcttctt attagcagat ttcgcaaatg gactgaaaaa gtcccacaaa gcaatcaagc
    11761 cattgctgct agaccaacgt ctagtgactg gtctaggtaa tatttatgta gatgaagcat
    11821 tatgggaagc gaagatccat ccagaacaac cggcgaacac actgcgcccc aaagaggtag
    11881 aacaattacg tctatcgatc attgatgttt tggatcgtgc aatagaagcc ggaggtacca
    11941 cgattcgcag ttatttgaat gcattaggag aatcaggcgg atttcaagta gcactgcatg
    12001 tctatcagca aactggcaaa ccatgtatac gttgtggaac gccgatcgtg aaaacaaaag
    12061 tggcacaaag ggggacgcac tattgtccga attgtcaaag gctaaaaatc gcaaagtagg
    12121 atttgtttta ggtttgacgg gtggaatagc taccggtaaa agtacggcag ccaaagtctt
    12181 tcagtctcat ggatttcctt tgatcgatgg cgatgtgatt gccagagaaa ctgttgagcc
    12241 tggaacgctt gctctgagga aaattgtatc agtgtttggc caagaggtat tgcagcctga
    12301 tgggcaacta gatcgaggga aacttgggat gattgttttt ccatcaaagg aaaaacggca
    12361 aaaacttgat cagctattag atccgtttat ccgaaaagcg ataaaagatc aaatcgcctc
    12421 tctaagttcc aatcatcctt tagtaattgt agatatccca ttgctctacg aaggtcatta
    12481 tgaccactat atggatgcag tagctgtcgt ttatactacg ccagaaactc agcttcagcg
    12541 tttgatgaaa cgtaatcaac tgacgctaga acaagcgcag cagagaatta gtagtcaact
    12601 tccaatcgaa gaaaaaaagc agcgtgcgga tattttgttc gacaacaatg gaacaaaaga
    12661 aaaacttgtg ggacaaatcg aaaattggct ttttgctaat cgctttcttt gagtatctgt
    12721 gtcaattttg ctatcctgag tatatagaaa gtgagggata gcgatgggat cattaaaaaa
    12781 tcaaaaggat aaagtcgtag gtaacgcaaa agaaaaaatc ggcgagatgc tcaataaaga
    12841 aaatctaatc gatgaaggtc gtacgcaatc agaaacagca gaagaaaaag aaaagcagta
    12901 ccaagcaaga atcgatgaaa tagaagacca gcaggcagaa gaagaagcga agcggcaaga
    12961 tttgactcaa gaacgaaaaa atccgacacc tgatcgtagt aaaacaccgc tcccagaaag
    13021 tgaccacatt tccgatgagc aaaaaatcga ggaacagcga atgaaacact atacaggaat
    13081 cgaagagaag ttataaaata gtaaaaaatc gagatgtgac ttgaagcaga tgagaaggtg
    13141 ttcatctgct tcaagttttt tgtgctagat gactaaatca gcttttgtgt aagttatttc
    13201 tcagtaatca aggtgatcag tattggaaaa ttgaaattta gtaaggacag gggacacaat
    13261 tacgcatgaa agtagaaaaa attgttctta tatccgtgtt ttttgggtag gacagtcgcg
    13321 tttgtgattt gtttcgtgtt ataatacaac tagttgtaaa gaaagacaca tcctttatat
    13381 aaaatgcgat gcaagaggtg agacaaaatg agatgtccca gatgtcaaca taataattca
    13441 cgagtaatcg acagccgtca agcagatgat ggacgtgcga tccgtcgccg tcgcgaatgt
    13501 gagaattgtt cgttccgatt cactacattt gaacgaattg aagctgctcc gttattagta
    13561 atcaagaaaa acggggaacg cgaagagttc aatcgcgata aaattttaag aggactcatc
    13621 cgttcagcag aaaaaagacc tgtagctatg gaacaaatgg aacaaatcgt caaccatgtc
    13681 gaaaaccgcg tacgcagtct cggagaaaac gaagtatcga cgaatctaat tggtgaatat
    13741 gtgatggaag atttagttga tttagacgaa atcgcttata ttcgttttgc aagtgtttat
    13801 cgccagttca aagatatgtc tgttttctta aaagagttgc aagatatcgt ggataaagca
    13861 aaagaaaata ataaagagaa taataaagaa aacaattaag aaacaaaaag gaggcatttc
    13921 cttggaaaat gcttggaaag agcttcaacc aaaaaatatt taccaaggaa gaaaagcggc
    13981 tccgctgaga gaagacagca agaacgcctt gctgtatctt tatcagccac taatcggcgg
    14041 agaagccttg agtatctatt tcaccctgtt atcagaaatc tctcaagaat ctggcaaagg
    14101 tcctgaaggg atgcatgcag atctgcttag tagtctaggc tgcggtatcc cgcaatttta
    14161 tgatgcaaga aaaaagctag aaggaatcgg cttactggat gtttatttta aagaagatag
    14221 tgatctggga cctcgtttta tttatgagct gttagaacca ctcattccta aagcattttt
    14281 caaagactct gttctggctt ttcttcttct ggaaaaagtt ggtgaacgac gattccagaa
    14341 gcttacccaa ttctttgaac ctaaaaggca tacagcagag ggatatcaaa aaatcacaaa
    14401 aaaattttta gatgtttatc gcttcaatga agcagtgtac gctgctaatc aagaaaacat
    14461 cgaatcgctg aataaatctt ttgaagaatc tgaatcagta gcattacttg aagcagattc
    14521 gacattcgat tggcagtttt tgaatgattg gctggcaaaa aaacatattg caagtcttga
    14581 tgatccaatc atcaaacaag tcgacatgta tcatcagctt tacggtttcg atgaattgac
    14641 acttggcgaa ctgatcagtc aatcttatga ctttagtgaa caaaaagtat ctgaaaaaga
    14701 actgcaaaaa gccattttgg caatgcagag acgtccggtg aagcaaacaa aagaaacagt
    14761 tgcggtttct gaaaacagta atgaaccctc gtcaaacgaa catttgacaa acgcagcgct
    14821 tcagctgata aaagaagcac agagcattcc accgatgaaa tatctggaag caatcaagtc
    14881 agaaaaaggc ggatatgttt ctaaacaaga aaactggtta ctgcaagatc ttgtttctca
    14941 atcaggtctt tccagtagcg tgatcaatgt tttgctgaat tatgtactag tgatcaagaa
    15001 taatgctagc ttaaatgcca gttatgtaaa tacagtggca aatgaatggg cacaaaagaa
    15061 aatcgccaca gcagaagaag cgatccagca cattcggcaa ataagtaatc aagcaaaaca
    15121 atcaaaacaa aagaagcaaa caaattatca aactggcaag cgaaatgttc gacgggaaaa
    15181 gcttcctgat tgggtcaacc agccaaaaga tgaaaaacag atcagcagcg agaaaaaagc
    15241 agagattgac cgccgtttta aagaatacct ggcaaaaaag gagggtgata tctagtggaa
    15301 gacgtaggca aagaattgaa gaggatcatc agcaaacgca attatcaaga aaagtatgct
    15361 gaaatgatcg ctgaagtctt aaatgatgcg gatgttcaag cttttctaag cgcacaccaa
    15421 gaagaattga cacaagcgga tattgaaaaa agttacgcta aattgtatga attcgtgcaa
    15481 gaaaagcgta aatatcaaaa aaacgatcca acgatgatcg ctcccggcta tgagccgaag
    15541 ctgacgttga attttcatta tgtggatgtc acttatgtac caacggaagc attgttagca
    15601 cggcaaagac aagaagaaat cagaagccga gtaaaagcaa tggatatgcc aaaagatatt
    15661 caatcggctt cttttgaaaa ctttgaacgt acagatggac gaggatatgc gagcttagaa
    15721 gccctagatt ttgtagagaa atatactgct gatccaaaag ggtatcataa aggactgtat
    15781 ctagtaggaa gttttggtat tggaaaaaca tatttattag gagcaacagc gagagaatta
    15841 gcgattgctg gattcaccac gacgctagtc cattttccga catttgccgt tgagatgaaa
    15901 caggcaatcg gaaaagatca agtggcagaa aagttagatg cagtgaaacg ttcacctatt
    15961 ttgatgatcg atgacattgg tgcagatgcg atgagtagtt ggatacgaga cgaagtattc
    16021 ggtgttatcc ttcaatatcg gatgcaggaa cagttaccaa ccttcttctc atcgaatttt
    16081 acaatggatg aattggaaca gcatttgtcc gtcactcaac gtggagatga agagccgcta
    16141 aaagcgaaac ggataatgga acgcatacgt tatttgacaa aagaaatcga aatgactggt
    16201 cgcaaccgac gcaatggttg aacagttgac aagtccaact gacatttgac ctagtagtaa
    16261 aagcaggtca gcgaatcatt atatggacag aaatgaccgg agacaatcac cgcaacaagt
    16321 aatgcagaaa cttaaacgga ggatttttta tgagggctat tttttctagt atatctgtag
    16381 ttggtctatt ttttctttta gcaggctgcg gtagcgcaga tagcaacaca ggttctgttg
    16441 attcgattga tgcgggtcaa acagtaaaaa caagcagtac gaaaacggag agacaaagca
    16501 tatttgtcgg aacgattgaa agtattactc aagtagaagc agaagaagaa acgcttcagt
    16561 tgaaactcgt cgatgtcatg gccaaagaag atccagcgaa tatgggaacg tcattcagca
    16621 atgacggagt gatcttaaat gctactgctg aaaaaataag cgtggacata aatgaattga
    16681 aaatcggtga caaagtccaa tttacattag ttgagatgcc gatcatgacg atgtctatcc
    16741 caccgcaagt tcctggagat tcgattattg atgtttcatt gaacaaataa ccaataacat
    16801 tttttcaaaa ataagaaaat gttgttttat agaacgaaaa ggtatatttt ttaaggagat
    16861 atggga
//
LOCUS       DAFEKH010000060        16823 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.063, whole genome shotgun sequence.
ACCESSION   DAFEKH010000060
VERSION     DAFEKH010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16823
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.063"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(39..405)
                     /gene="ssrA"
                     /locus_tag="LP386_002300"
     tmRNA           complement(39..405)
                     /gene="ssrA"
                     /locus_tag="LP386_002300"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(576..1349)
                     /locus_tag="LP386_002301"
     CDS             complement(576..1349)
                     /locus_tag="LP386_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL1919512.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            1493..1843
                     /locus_tag="LP386_002302"
     CDS             1493..1843
                     /locus_tag="LP386_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBL1919513.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            1824..2540
                     /locus_tag="LP386_002303"
     CDS             1824..2540
                     /locus_tag="LP386_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1919514.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            2540..3988
                     /locus_tag="LP386_002304"
     CDS             2540..3988
                     /locus_tag="LP386_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL1919515.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4058..4567)
                     /locus_tag="LP386_002305"
     CDS             complement(4058..4567)
                     /locus_tag="LP386_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919516.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(4557..5282)
                     /locus_tag="LP386_002306"
     CDS             complement(4557..5282)
                     /locus_tag="LP386_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919517.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            complement(5540..6880)
                     /locus_tag="LP386_002307"
     CDS             complement(5540..6880)
                     /locus_tag="LP386_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBL1919518.1"
                     /translation="MSYSEFTKELLDILDLNLTFHEDAFRKERINDETCFVFDGTLTY
                     QPEECFHCHYQNKQTIIKWGWKKVSILLNDVSNYKTIVRINKQRFKCKHCGKTFLAED
                     SVSDRRCSIARRVKQAILELLSEPISMSLIARMKHISPTTVIRILRSLRPKTVSLNQP
                     LPEVVCFDEFKSVKNVSGAMSFVMMDGKTHQLIDIVENRQLNPLRDYFLRYPRKVREQ
                     VRLVVSDFYTPYRTLVKECFPNARIVADRFHISQHIGRAFTNHRIQVMKTFKKGDRRS
                     KHLKKYWRLLQKNAWELNGQHRYWRPSFRDHLTEAEIVDRLLYYDDSLKRGYEVYQVF
                     LSAIRRQDVPEFVALLKEDYKELPEHYQPVFTTFKKYRTEIKRALRVPYSNGPIECLN
                     NHIKVLKRIAYGFRNFQNYRERIFLYRGKYFKKTKNTTQLTKARTTTRLDKIAV"
     gene            complement(7047..9167)
                     /locus_tag="LP386_002308"
     CDS             complement(7047..9167)
                     /locus_tag="LP386_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBL1919519.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYISAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            9397..10575
                     /locus_tag="LP386_002309"
     CDS             9397..10575
                     /locus_tag="LP386_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HBL1919520.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            10591..11349
                     /gene="aroD"
                     /locus_tag="LP386_002310"
     CDS             10591..11349
                     /gene="aroD"
                     /locus_tag="LP386_002310"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBL1919521.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFFSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            11372..11857
                     /gene="ybaK"
                     /locus_tag="LP386_002311"
     CDS             11372..11857
                     /gene="ybaK"
                     /locus_tag="LP386_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HBL1919522.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(11928..13181)
                     /locus_tag="LP386_002312"
     CDS             complement(11928..13181)
                     /locus_tag="LP386_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBL1919523.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            13298..14647
                     /gene="gdhA"
                     /locus_tag="LP386_002313"
     CDS             13298..14647
                     /gene="gdhA"
                     /locus_tag="LP386_002313"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HBL1919524.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            14759..16105
                     /locus_tag="LP386_002314"
     CDS             14759..16105
                     /locus_tag="LP386_002314"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HBL1919525.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(16413..16799)
                     /locus_tag="LP386_002315"
     CDS             complement(16413..16799)
                     /locus_tag="LP386_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBL1919526.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         5407 a         3035 c         3443 g         4938 t
ORIGIN      
        1 aaggatttaa gcatctagcg aaatctgctg aaatctcaca atggagacgg cgggagtcga
       61 acccgcgtcc aaacacatcg ccacttaaaa atctacgttc atagtcaact catttaagga
      121 ttcactttac agcttgccga gtgacaggca ttctgtatcg ctagtctgat gttctctttt
      181 tcaacttaca gacggaaagt tgaaacgtat cccactaaag ttaggaccct tactcgagca
      241 catgggcgat gccgagagga tctacgctaa ctgtttttag gcagctaaag cgtaagagtt
      301 gttttcgttt ttagcagtta tatttaactg taacgttttt acgtagacgt aacctacgaa
      361 acgcaattca agctcgactg tgcctgtcga atccgtaacg tccccgttag ctaacaaggg
      421 ttacgtgtat ttttcataca aaattagtat agcatatatt gggataaatt caataaaaaa
      481 gcgaatcata tcccattatt tatataataa ctgccccttt cttaagaaaa aataagcgat
      541 tttcttaaga aaagaggtag cttcaaaaaa agatcttaaa tcagatcaaa atacttcaat
      601 gcgtggacaa ttccgccttc tgtatttttc tttgtgataa aggtagaaag ttcttttaat
      661 ccgtcatagg cgttgcccat agcgattttg ttgtcgcaag cttccaacaa ggcaaaatca
      721 ttcggaccat cgccaaatcc aaaagtagga actttttcca gctgaagttc tttttgcaga
      781 cgtttgacac ctgccccttt tgagattcct ttcttcactg tatcgatcga gtaaggacca
      841 ttccgataaa aagttagctc aggaaaatgt tcgtgatagt attcgtcacc tgattgagat
      901 aagatcagca acatatttac tgtgttttct ttaaagccta aaggatcaat ttccggaaca
      961 tctgaatgaa tgaagtcgta agcattgatc attgtttggc tatgaccggt acaccagatt
     1021 ttctgatcgt tatagtaaga aagttcatga ccgttcaact gtacatgatc atacattttt
     1081 tgacattctt ctgaagaaaa tgtttgagaa tagatttctt cgccgtctac tcgaatgaaa
     1141 gaaccattca tggtgaccgc agaagtaatg cccgcatctt ccatgataga gtggatttct
     1201 gcttctgtac gtcctgtagc gatgacgggg agaacattgt tttcttttaa tgcgttcata
     1261 gcttttgcca cttcgggtgt gatttttgat ttcgcatcta gtaatgttcc atcaagatca
     1321 aagaaagtga ttgcacgata atttgacaca aataaaactc cttttttatt ggaataagtt
     1381 tatcttaaca aagaatgaac aaaagacaaa cctttcgtga agaattcctg aacatattgg
     1441 ttcagtcaac aatttagagt atactataag aagagaattt aggagggaaa gaatgatttt
     1501 tttcagtatt ggtatcttat tcttaataat tggcagtctt tttcggattc tgccctcaaa
     1561 aggaaatctg cctttttatg ggtatcattc gcctcttgcc gcaaaaacag acgctcattg
     1621 gcggctggct caaaagacaa gcggaaactg gttttttctt atgggcttac tgatggcatt
     1681 gatcggctat tatttaaaga catctgggca tacgaattat tttctgattg aaatgcttct
     1741 gctagtattt ccaattatgc ctatttttat tatgacagaa aagaaattac agaaatatga
     1801 cctggaaact ggagggaacg ataatgaata ttttaatgat tgaagataat caatctgttt
     1861 ctgaaatgat gcagatgttt ttcttaaatg aaggttggga agcaactttc aagtatgatg
     1921 gaaaagaagg gctcgatgcc tttttagaaa acccacaaca ttgggatatg attacactag
     1981 acctgaattt gcccacactg gacggtatgc tagtaggaag agagatccgc aaagtttcaa
     2041 gtactgtgcc gattatcatg ctgacagcta gagattctga aagcgatcag gtgatcggct
     2101 tagagatggg ggcagatgat tatgtcacaa aacctttcag tcctctgacg cttattgctc
     2161 gaatgaaagc tttgcatcgc cgtagtgagt tggcagaagc aagagaagaa gcagtagttt
     2221 cagatgatca ttttgatatc gagactagtc atttcaagat gaatacgaaa acacgagaag
     2281 cgtatctgga caaccggcca attgaaggac tgacgcctaa agagttcgat ctattgttta
     2341 ctttagcaaa aaaaccacgt caagtattct ctcgggagca gttgcttgaa ttagtctggg
     2401 attatcagta ctttggtgat gaacggacag tggacgccca tatcaagaaa ttacgacaaa
     2461 aaatcgaaaa ggtcggacca caagtcatcc aaactgtttg gggagtcggc tacaaattcg
     2521 atgattctgg tgttgcctaa tgcgttattt gtatcagcaa ctcttagctt tctgcggaat
     2581 ggtcgcgttg atcttattga tcgttggagt ttcttttaca caactgacaa aacaaacgat
     2641 tgaagaaaac aattaccagc aactgtttgg atatgctgaa tcagttgaaa agacaacgca
     2701 aacctatgcc gatacgctcc cgcagtttag tcaagatcag gcgtttcaaa atgcattgct
     2761 gctgacagag caagtactga cagaacaaaa tgtgaacttt atatttatcg ataaaaacga
     2821 acgtgtcatt tatccgacta atacagcttt actgaatttt accttaacag ctgatcaatg
     2881 gaaaaatctg aggaatggac gtcaagaaaa attcacatcg aataaaaata ttttaggaca
     2941 agcacaggcg acctcttacg cacttgtgcc atttaatttg aatcatgaat tctatggagc
     3001 acttgtagtt agtcaacctg cgcgaaatat cgataacagc gttcgtccaa ttacactgaa
     3061 cctgttcaaa ggatttattt tttccagtat cgttgcagtt attgccagct atgcttttgc
     3121 agcattccaa gttaagcgta tcaatcggtt aaggaatgcg acgaaagaag tgacgaatgg
     3181 taattttgat gtacagctcc ccgtacatga caaagatgaa tttgatgagt tagcagatga
     3241 tttcaataaa atgacgaatt cattgaaaga atctcaagca gaaattgaag aacaagaaaa
     3301 tcgtcgaaga caatttatgg cagatgcttc tcacgagatg agaacacctc ttacgacaat
     3361 caacggactt ctggaagggt tagaatacaa tgcaatccct gaaaatcagc gagaaaacgc
     3421 gattaaattg atgaaaaatg aaacagagcg tctgatccgt ttggtgaatg aaaacttgga
     3481 ttatgaaaaa atccgtacga atcaaatcag tatggtcatt aaaaaattca atggaacaga
     3541 aacattgaaa aatattgttg cacagttaga agctaaagca gaagcagcag gagatacatt
     3601 gacattgaaa gccgttgatg atattgatgt ttacgctgat tatgaccgat ttgtccaaat
     3661 catggtcaat attattcaaa acgcgataca gtttactgaa aacggccaaa tcacgattac
     3721 tttagaaaaa ggctatcttg aaacgatcat cacgattgaa gatacgggaa ttggaatgtc
     3781 tgaacaacaa atgaaaagta tctgggatcg ttattataaa gtagatcctt caagaaaaaa
     3841 tacaaaatat ggtgaatcag gattaggttt accaatcgtg cagcaacttg tacgcttgca
     3901 taaaggaaaa ttagaagtag aaagcgaact aggaaaagga acaaaattcg ctgttcgttt
     3961 gcctgacgta gaaatcaaaa aagagtaaaa aacaagcggt ataaaagatc atgaatcgat
     4021 cttctatacc gcttgttttt actataaaat gattgattta gcccgcgggc tctaaacgat
     4081 caatataagg actttgagca atagtagcat catgagtaaa gagtaagata ccttgatttt
     4141 cttcatgagc taaataagaa agcaagtgga gtagctcttg gatctccaat acactaagtt
     4201 catcaaatgt atcttcaata acaatattgt ttcgcttgga aagcaaggca tgaagtaatt
     4261 gcagctttac tttttcaaaa gacgtcaact cagctgccgc acaattaagc aaggaaggag
     4321 agatatcaag tttttcttga taggccaaac gatcttgttt gatttctttt tccggtacat
     4381 ccaacaggac atggtcttta agattcagat aaggaaacat cggccaattt ttttggatga
     4441 tcgcaaaatt atccagtttt gcaacaagaa cctctttttt caagtgctcc aatattttat
     4501 gctgtttttc gagaggacac aaaataacgg tcaagtgttc agcatgaatc aaatattcag
     4561 gtttcattac gtccaggcct cctactttgc aaatgatgga taaaaaaagt gaaagggaat
     4621 agactaagaa tgagacagca tccactgagc ccaataagag tttgggcaaa tcccttaagt
     4681 atatctgtga aaaaaagatc attttggaaa tcgatggtaa aaaaagtctg ttgatccatc
     4741 ggaattgtaa gtccgcttac cgaagtcaag atatcacgga tatctggcag ttcagtagtc
     4801 tttaagacaa gaaaattgat cctttgaaga agcgcttcat aaactgactg gaagcttacg
     4861 atccacaata aaaccaagat acaacaaaga aagagaggaa agaacagctg ccagaaaata
     4921 aaaaggaata atttggtttt agaaagacca gtcaggtgcc aattgatcaa ttcctgcttg
     4981 ttttgcctga ctgaatagta aaagaaaaag ataaaaagga aggcaaatag aaaaaataaa
     5041 ctgaatatgc cttttatata aaatcggcta gctaattcta aagccggaag aagctctgta
     5101 gatgcagaag cgccaataaa tgaaagccga tcttggactt gattggctaa agccgattgc
     5161 aaatggtaaa gagtcaggca tgctatcaat aaaaaagcag aaaagcttga aaataaacaa
     5221 tagagtattg tctgcttttt gtaataaatt aatcgagcag tagcatagcg gattattttc
     5281 atacttttca cctctataaa aagtatagaa aatgaatatg aataaagtat gaaattcctt
     5341 tagtgaaatc acgaattaaa accagaaaat attttgtaaa aagcaagagg ttgtgaagaa
     5401 gctgccctat tctattaccg tagatgcaag cttttgaaca ctgtttattc gaaaagagga
     5461 gcagcgacaa taattttggg ctcttcgtca atgagtgttg gtgaagaaat tcaatagaat
     5521 aatcgagata ctcacacggc tagacagcta tcttgtctag ccgtgttgtt gttctggctt
     5581 tagtcagttg ggtagtgttc ttagttttct tgaaatattt tcctcgatat aaaaagattc
     5641 gttctcggta gttttgaaag tttctaaagc cataggcaat tcgttttagt actttgatat
     5701 ggttgttcaa acattctata gggccgttgg aatagggaac tcgcaacgct cgtttgattt
     5761 ctgttcgata tttcttgaag gtcgtgaaca ctggttgata gtgctctggc aactccttgt
     5821 agtcttcttt taggagcgcg acgaattcag gaacatcttg tcttctgata gcggaaagaa
     5881 aaacctggta gacttcgtag cctcgcttta aggagtcatc ataatataat agccgatcga
     5941 ctatctccgc ttctgtcaga tgatctcgaa atgacggacg ccagtagcga tgctgaccat
     6001 tcaattccca cgcattcttt tgaagtagtc tccagtattt ctttaagtgc ttcgaccgac
     6061 gatccccttt tttaaaggtc ttcattactt gaattcggtg gttggtaaag gcccgaccga
     6121 tgtgttggct aatatgaaag cgatcggcga cgattcgggc attcggaaaa cactctttca
     6181 ccaatgtgcg atagggtgta tagaaatctg aaaccactag acgtacttgt tcacggactt
     6241 ttctagggta gcgcaagaaa tagtcgcgta aaggattgag ttgccgattt tccacaatat
     6301 caatcagttg atgggtcttg ccgtccatca tgacaaagct catggctccc gagacgtttt
     6361 tcaccgattt gaattcatcg aaacacacca cttctggtaa cggctggttc aaagaaacgg
     6421 ttttaggccg aaggctgcga agtattcgaa tgacagtggt cggagaaatg tgcttcatac
     6481 gtgcaatcaa agacatagaa ataggctcac ttaatagctc aagaatggct tgtttgactc
     6541 tgcgggcaat ggagcagcga cgatcgctaa ctgaatcttc tgctaaaaaa gtctttccac
     6601 agtgtttaca tttgaagcgc tgtttgttaa tccgcacaat ggtcttgtag ttactgacat
     6661 cattcaataa gatggatact tttttccagc cccatttaat gatcgtttgc ttattttgat
     6721 agtggcaatg gaagcattcc tctggttgat aggtcaatgt gccatcaaaa acaaaacatg
     6781 tttcgtcatt aatgcgctct ttgcgaaagg catcttcatg aaaggtaaga tttaggtcta
     6841 gaatatctag taactctttg gtaaactctg aataggacat cttgaaacac tcctttgaat
     6901 ggttttcgtc gactttattc taaaggattt caaggtgtct gtttgcgttt attagaaaaa
     6961 agaaaaagta ttggcaacag aaggcgtcac caacactaga tattatagat cctaattttg
     7021 tcgctgctcc ttttaaattt attttatcat tcggaagaac ttgtggtcgt tccgtgaagt
     7081 tcttggtacg tttgcgtttt ataaagatca acagttgatt gtccgttgtg ttcactaaag
     7141 acactagttg acttgtcacc aagagatttt tcagcttctt ttaatttctc taagccattc
     7201 ttgtagtcat aatcactggt atcaattggg tctaatccac tattcgtata gaaccgaaga
     7261 agatcaccat tattgatttg gtcagaaaca gctaactgtt tatcaacttt ttctttcagt
     7321 gaatcaattt cattctgtac ttcctcagta ggttcagtaa tagcttcacc agtttcgtta
     7381 ctatagatcg taccaccgta gtaagtatat tttggtgtaa caaaatcacc atcacggaaa
     7441 gaaacaagct gttcatgatc tttcgagaat agatcttgtc ctaactgaat ataatttttt
     7501 gtatctacac ctagtaagtg aagtaatgta ggcaaggcat caacttgtcc gccgtaagtg
     7561 tgattgattc cgccctgtgt ttgtccaggg atatggatca tataagggac acgctgcatt
     7621 tgtgcattgt cgtagtttgt ccaagtagaa cttgtttttc caactaattc agctagattt
     7681 ttatttcttg aattcgagac accgtaatgg tcaccgtaaa ggacgatgac tgaattatca
     7741 tacaagccgc tttctttcaa ataattgaag aattcttgta cggcggtatc taaataattg
     7801 gctgtcgcaa agtaaccgtt gatcgtttca tcatttgtat tggctaacgg gaatcctgct
     7861 tcgtcattgg tgaattttga ataaggataa tggttagata cagcaatgaa ttttgaataa
     7921 aatggttgtt gcagacgttc caagtattgt acggattgtt ggaaaaatgg tttatcatgc
     7981 aacccgtatt ggaacgaatt gtcatcatta acatcataat aagaagaatc aaagaaataa
     8041 tcatatccta aattcttgta tgtctcgttt cgattccaga atgtaccagc gttcccatgg
     8101 aataccgcac taatgtaacc ttgtgtttga cttaaaatat caggtgcagc ttggaaagta
     8161 ttttttccgc ctaattgtgt gaacaaggag ccttgattca agccaaacaa tgaattttcc
     8221 atcagcgttt ccgcatcgct tgtttttcct gcttttactt gatggaaaaa gttgtcaaaa
     8281 ctgaacgtgc tgttgctgtg gtaaagacta ttgatgaaag gtgtaacttc atgctggaga
     8341 ccattctcat ctgtcaattt ataatcgatc aggaattgct ggaagctttc taaatggata
     8401 taaatcacat tttttcctct agcgagcccg aacaaatcgt catttggtgc tgcataatgt
     8461 tcttttacat aattttctac ttctttcata tcattgggac ttgcttctgc ccgcacttgg
     8521 tttgtctggt aagtttgaac accgtcataa accatgaaag cattcaagcc aagatatttg
     8581 accaaataat cacgagagaa tgttcgagtc agcaattctg gacgatcagc ttccgccata
     8641 aaaagatttc ctgagaaaat cataactgct aatgtagaga tcgcaaaagc cattcttgct
     8701 cggatcgggc gagggtccaa cttgattttt tttgcaatca gcagaacagt caagataata
     8761 aaatcgatcc aatagatcac atcatatggg cgaaacagtc gaatggcact ttctcccaga
     8821 ccactcgcta ctttcccagc acctaaaatc gtgttgatcg taatgaagtc cgtgaattct
     8881 cgataataag tgacattcga aaaaacaagc aatgtcaaaa gaaaataaat gaccatcatc
     8941 gtgatataag caactctagg gcgtctgata taaagagcaa ttccaagtaa taacaatgta
     9001 gttgcaatag ggttgataaa caagataaag tattgaatgc cactttcgat tccgagatgg
     9061 aaatcaacta aataggcaaa aatcgttttc aaccaaagta aaacgactag taaagaaaaa
     9121 aatccgagcc tcttattcaa aaaggcaggt gtttttatac atttcaagat aatcttcctt
     9181 tctgcacttc ttaatcacag aagtgtcctg aaaccatgtt acacagctca cttattctca
     9241 tttattttac tagtatgaca atatagtgtc aattgaaacc agaagtttat gctgtttcat
     9301 taaggttttc tttaagcttc atgaaaaaat gagcagtaag acaagtccta tgttttttgt
     9361 tatacttggg aagagaaagc taaagcaggt gaaggaatga aagtaaaagt aaaaaaaaga
     9421 gcaagcaatc gattgaaaaa aggatatcca ctgatccaaa aagaagacct tgctcatccc
     9481 caaaaagaaa ccacgcaatg ggtggaatta gttgattcgc aaaaccaatt tatcgcaaaa
     9541 ggatatctag gaaagcagaa taagggaatc ggttgggtat tgagccagca gaacatccca
     9601 tttgatcaat ctttttttga agaatttttt gtgaagtcaa aagaaaaaag aactttcttt
     9661 ttttcagatg attctactac cgcttttcgt atattcaatg gagaaggaga cgggatcggc
     9721 ggtctgattg ttgattatta tgcaggttat gctgtttttt cttggtataa cgaaacgtta
     9781 tatgcacatc gtgaattatt gattcaagct tttcgtgaaa tctacccgga aatcatagga
     9841 ggctatgaga aaattcgatt tgaatcagta aatctgcctg agagccagtt catttacgga
     9901 aaagaggcac cggaaccctt gatcgtaaaa gaaaacggag taaaatttgc cgtttattta
     9961 aatgaaggat taatgactgg gatcttttta gaccaaaaag aagtacgggg atcattagca
    10021 gaaggtttcg cttctgggaa aacagttttg aacatgttta gttataccgg cgccttttct
    10081 gttgctgccg caatgggagg ggcaatcgaa acaacaagtg tcgatctagc aaaacgcagt
    10141 ttaaaaaaaa cacaggaaca gtttgaagtg aatggtttgg atgtcgatca gcaaaaaatc
    10201 attgttatgg acgtattcga gtatttcaaa tacgccaaaa gaaaacaatt tttatatgac
    10261 atgattgtat tggatccacc aagttttgcc agaaataaga aaaaagtctt tcgcgtagca
    10321 aaagattatg gggaactggt caaggatagt ctggatattt tagcagaaga cgggatactt
    10381 attgcgtcta caaatgctgc gaatgtctcg atagaacaat tccaaacaat gattgaagag
    10441 gaattccatg ccaaaaatgt ttcttttgaa caacttgctt tatatcgtct gccaaaagat
    10501 ttccagacga cggatacctt tttagaaggc aattatctga aagtgtttgt ttatcaaatt
    10561 aaaaataacc attagaagga gcgatgcaga atggttcggg taaagggatt gaatatagga
    10621 agcggtagac caaagatttg tgcgcctctt atcggggccg tccgagagga agtattacgt
    10681 gaagcagttc ttgcacgtga agcaggggcc gatttagtcg aatggcgagt cgatcattat
    10741 cgtgaagttt tttcttttga tgaagtagca gaaacattgg ttcttatcca tgagatgctt
    10801 gatggactgc cgttattatt tacgtttcgt accttagctg aaggcggaga acaagacata
    10861 tcgatccgtc agtatcgcga cctttatgaa catgtgatac acacaggatt agtagatatg
    10921 gtcgatatcg agttgttcaa agtagaaagt ctaggaaaaa gactgataga ggaaatcaag
    10981 tctttaaaca ttcctttaat tatcagtagt catgatttta aagaaacacc agcagaccct
    11041 gtcttgcttt accgattgaa tgttatggaa cattttggag ccgatatcgg aaaactggca
    11101 gtaactccca ataatgaacg agatgttttg cggttgatgg agttgactag acgggcaaat
    11161 gcttttttct ccatgcctat tattacgatg tccatgggaa atcttggtaa aatttctcgt
    11221 ctggttggcg gaacgacggg ttccgttatg acatttggtt ccttaagcag cgattctact
    11281 tctgctccag gacaattacc ggtcaaagca ttgaagcaaa ttattcaatt attaaatgaa
    11341 ccgttgtaga acaagtttga ggtgatattt tttggcaaag aaaaaaatag taaaaacgaa
    11401 tgcaatccgt atggtcgaac aaaaaaagat tccctataca gagcacgaat atgagtggga
    11461 cgaaagccac ctaagtgcgt catcggtcgc tgaacagctt ccagaaagcc aatctcgtat
    11521 atttaaaaca ctggttgctg tgggcaatgt gacggggcct cttgttgctg tgataccggg
    11581 agaagccgaa ttgaatctaa aaaaattagc aaaagtttca gggaataaaa aagtagaaat
    11641 gctccattta aaagatttgg aagcaacgac cggatacata cgtggtggct gctcgcctat
    11701 aggtatgaaa aaactatttc ctacttattt agatcaaatt gcagaaagct atgaacaaat
    11761 cattgtctcg gctggcagaa gagggctaca gatggagtta gcacctcaag atatctgtgc
    11821 attaacgagc ggacaatttg cagatataaa acaataaatc atacgtataa aagaaagaag
    11881 gaggccggga tgttgtttgt ccagtctcct tctttctttt ttatacatta tgctctttgc
    11941 ccggcattca ttcctgctac atgccctgta gcgaaagccg ctgtgatatt aaagccgcca
    12001 gtataaccat tgacatccag taattctccc gcaaaataca gaccatcaat gattttactc
    12061 tccaatgttt taggataaat ttcctttaga gaaacccctc cgccagttac aaatgatttc
    12121 tcaataggaa aagttttgtt gattgatagc ttaaactctt tgcatagttg aacaaaatct
    12181 tgaatttgtt tttgagaggc ttgttgtcct gtcagatgat ccatttcaag ccgctcaaga
    12241 aagaaaacta acaatcgctc aggcaatata ccatgccaag cattgaccaa gttctttttg
    12301 gttgctttac ttttttctgt caatatatga ataagctctt gtttggtttg tgtagggaaa
    12361 caatccagag aaagtgtcac tggttctccc gttttctcta attctttatt gacaaaactt
    12421 gaacaacgca gtgcagccgg accagaaata ccgaaatggg tgaaaagtaa atccatcgta
    12481 tgttcagtca atacacgacc ttttttattt aaaacgcgta aagtgatgtc ttgtaaagaa
    12541 agcccttgaa gtgttttctc ctgaatatac ggttcatccg atatcaaggg ggactctgtc
    12601 gcataaagag gcgtcaccgt gtgacccact cgcttcacga tcttgtaccc atctccagta
    12661 gaaccagtag atggataagt ccgtccacca gttgttaaga taatggcagg agcatggaac
    12721 tcttcgaatt ccgtgcgtat accgtaaatt ttatgttctt tgtggatcaa tttctctact
    12781 cgagtagaga atagaagcgt cacatctagt tctttcagac gattgagcaa tgcttcgata
    12841 atcgtttttg atttatttgt tacaggaaac atccgtccat gatcctcttc ttttaaatgt
    12901 acgccttgtg attcaaagaa gttcatgata tcgaaattat tccattgcgc aaacgtacta
    12961 tataaaaact ttccatttcc aggaatatgt gcaatcaaat catcaacagg acgattgttc
    13021 gtaacattgc accgaccacc acctgtcatc agtagttttt ttcctgcttt tttgtttttt
    13081 tcgatcaaga gtacgcgtgc gccttgttca gctgcactga tcgctgccat catcccgctt
    13141 gttccagcgc cgactacgat cacatcatac agtttttcca ttccctcacc tcaaggaaag
    13201 tgtagcatat ctgaagaaag aaaacagaaa aaaatgtttt gagccaaaag agaaaatgag
    13261 ctaaaatgag ggaagataag caaaggagcg tggaacgatg acaaacgcaa cagaatatgt
    13321 tcaagcaatt caagaaaagc tacatcaaaa ggatcaaggg caagaagaat ttttacaagc
    13381 aatcgatgaa ttcatgccca cggttatgtc ttttttggac actcatcccg aatatatcga
    13441 aaagaatatc ttagaacttt taacggaacc agaaagagtt attcaatttc gagtgccttg
    13501 gcaagatgat gaaggaaact ggcgagtaaa tagagggtac cgtatccaat acaactcagc
    13561 tatcggccct tataaaggtg gattgcgctt ccatcctagt gtcaatctaa gtatcttgaa
    13621 atttttggct tttgaacaga ttttcaagaa tagtttaacc ggtctgccaa tcggtggagg
    13681 aaaaggcgga agtgacttcg atcctaaagg aaaatctgat aatgagatca tgcgtttttg
    13741 tcaaagtttc atgctggaat tgtcaaaaca tatcggccca tcgattgatg ttcctgcggg
    13801 agatatcggt gtaggagcta gagaaatcgg ctatttgttc ggcgaatata aacgattgaa
    13861 aaaatatgat actggtgtgt tgacaggtaa acctttggat ttttggggaa gtaagatacg
    13921 tacggaagct actggttatg gattagtgta ttatgtcaaa catctattga acgaagaaaa
    13981 agattcattt aatcaaaaaa cagtttttgt ttccggaagc gggaatgtag ccatttatgc
    14041 aatcgaaaaa gtgcaagagc taggcgggaa agttgttaca tgttcagatt ctagcgggta
    14101 catctatgat ccagaaggaa tagatgtgaa actattgaaa gaagtcaaag aaatcaatag
    14161 acaacgtttg acggaatacg caaaccaacg tccttctgct atttatcatg ctggagaatc
    14221 tgtttggaca ttgaaagaaa aagcggatat cgctttgcca tgtgctactc aaaatgaaat
    14281 agacgaaagc ttggccgaaa tcttagtaga aaatgggatc aaaatcgtag cagaaggcgc
    14341 taatatgcca tgtacagtaa aagctgtttc tgttcttcat gaagcaggcg tgtggtattg
    14401 tccaggaaaa gctgctaatg ctggaggagt agcagtatct gctttagaaa tgagtcagaa
    14461 cgtccagcga ttgacttggg aaagagagca agtggatgag cagctggatc aaatcatgga
    14521 aacgatttac catacgtgtc gccaaacagc agccgagtac ggcgacgaaa aaaatctgct
    14581 tcttggagca aatgttgctg gatttgaaaa agttgccaaa gcaatggcag cagaaggttt
    14641 agtttgaaaa atgaaacttt cttggaaata ttgtcagcat tttgtttatt tgcttgaaaa
    14701 ataataaaaa aaaacgtaaa gtattacctg tagagtaaac ctataaggag gagaacaaat
    14761 ggcacacatt cattttgact attcaaaagt agcaccgttt gtcaacgaac aagagttagg
    14821 gtacatgcaa agccaagtaa cagcagccca caacgaatta cgggaaggta ctggcgcagg
    14881 aagcgacttc cgcggctgga tcgatttacc aacgaactat gacaaagaag aatttgcacg
    14941 tatcaaagaa gcagctaaaa aaatccaatc tgattctgaa gtattagttg ttatcggtat
    15001 cggtggttct tatttaggcg ctcgtgcagc gatcgacttc ttgaatcaca cattcttcaa
    15061 tttattagat agcaacacaa gaaaagcacc acaaatcttc tttgccggaa attcaatcag
    15121 ctcaacatat attgctgact tgatcgaagt aatcggtgat cgcgactttt cagtaaacgt
    15181 tatttcaaaa tctggaacaa ctactgaacc agcgattgcg ttccgtgtat tcaaagagct
    15241 tcttgttaag aaatatggac aagaagaagc aaacaaacgt atctacgcta caacagataa
    15301 agcaaaaggt gcagttaaag tagaagcaga tgcagaaggt tgggaaactt tcgtgattcc
    15361 tgatgacatc ggcggacgtt tctctgtatt aactgctgtt ggtttgttac caatcgctgt
    15421 tagtggtgca gatatcgatg cattgatgca aggtgccgct gatgcaagca aagcatactc
    15481 aagcgacaaa ctagaagaaa acgaagctta ccaatacgca gcaatgcgca acattcttta
    15541 ccgtaaaggc aaagtaactg agttgttgat caactatgaa ccaggaatgc aatacttctc
    15601 agaatggtgg aaacaattgt atggtgaatc tgaaggaaaa gaccaaaaag gcatctatcc
    15661 ttcaagcgca aacttctcaa ctgatttgca ctctttagga caattcatcc aagaaggacg
    15721 tcgcaatatt tttgaaacag ttgtgaaggt tgaaaaacct cgtaaatcaa tcacaattcc
    15781 tgaacaagca gaagatttag acggtctagg ctacttgcaa ggaaaagaag tggacttcgt
    15841 aaatacaaaa gcatttgaag gaacattgct tgctcataca gacggtgacg tgcctaactt
    15901 gctagtcaaa attccagaaa tggatgctta tacattgggt tatacaatgt acttctttga
    15961 aattgctgta ggtatttcag gttacttgaa tggaatcaac ccattcgacc aaccaggtgt
    16021 agaagcttac aagaaaaaca tgttcgcact tctaggcaaa ccaggctttg aagatcttgc
    16081 taaagaattg aacgaacgcc tgtaagataa gggtttttcg ctagatttaa ataatcagtg
    16141 atagaaacat gttcgcttta aaatgaaaac tggtacccat ttaggtactc aaacatactg
    16201 catcgtttat tcagaataag gggctgtgac aagacgtttg tcacagtccc ttgtttgtat
    16261 agaaatcgat tgattgcctt gctctttagt ttgttttagg actttaagaa cagtgaggct
    16321 gacttcgaag gttaattctg tttttttgtt ttctagaatc agtaagcaaa aaagcactca
    16381 cttcgagtgc ttttttgcga tatattctta gcttaagata ggcctaattt ttcttttaca
    16441 gatgagggta ccttatcgct ggtaattact tttttctcta tgatccgctt ttcgcttgct
    16501 ttcaactgca agatcgttcc ttcggggtaa gcagaaccat tggcagagtc accagaagta
    16561 atgacatcga aatctaactg tcttttttca ccgttttcag cataagcatc tacgttgtat
    16621 ttaaaacctc ttccaattac ttccccatta tctgctttga tatcagtttc tgcaggcatt
    16681 ggagctttga ctaccgcata ataatcttta cctacataag tagactgata gtagtcccaa
    16741 cctttccatc ctataaaagc aatcaatatg ataacgatca accctaaaat ttttttcatg
    16801 aaagatctcc ttttttattt tta
//
LOCUS       DAFEKH010000061        16527 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.064, whole genome shotgun sequence.
ACCESSION   DAFEKH010000061
VERSION     DAFEKH010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16527
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.064"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(141..416)
                     /locus_tag="LP386_002316"
     CDS             complement(141..416)
                     /locus_tag="LP386_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBL1919527.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(659..1969)
                     /gene="der"
                     /locus_tag="LP386_002317"
     CDS             complement(659..1969)
                     /gene="der"
                     /locus_tag="LP386_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HBL1919528.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(2151..3380)
                     /gene="rpsA"
                     /locus_tag="LP386_002318"
     CDS             complement(2151..3380)
                     /gene="rpsA"
                     /locus_tag="LP386_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HBL1919529.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(3515..4195)
                     /locus_tag="LP386_002319"
     CDS             complement(3515..4195)
                     /locus_tag="LP386_002319"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HBL1919530.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(4244..4879)
                     /locus_tag="LP386_002320"
     CDS             complement(4244..4879)
                     /locus_tag="LP386_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL1919531.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(4945..6348)
                     /locus_tag="LP386_002321"
     CDS             complement(4945..6348)
                     /locus_tag="LP386_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HBL1919532.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATKQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(6335..7366)
                     /locus_tag="LP386_002322"
     CDS             complement(6335..7366)
                     /locus_tag="LP386_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1919533.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESEVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            7397..7618
                     /locus_tag="LP386_002323"
     CDS             7397..7618
                     /locus_tag="LP386_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBL1919534.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(7783..8520)
                     /locus_tag="LP386_002324"
     CDS             complement(7783..8520)
                     /locus_tag="LP386_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HBL1919535.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(8673..10013)
                     /locus_tag="LP386_002325"
     CDS             complement(8673..10013)
                     /locus_tag="LP386_002325"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HBL1919536.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(10250..11773)
                     /locus_tag="LP386_002326"
     CDS             complement(10250..11773)
                     /locus_tag="LP386_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HBL1919537.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(12151..12762)
                     /locus_tag="LP386_002327"
     CDS             complement(12151..12762)
                     /locus_tag="LP386_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBL1919538.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(12885..13010)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(13092..13808)
                     /locus_tag="LP386_002328"
     CDS             complement(13092..13808)
                     /locus_tag="LP386_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBL1919539.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(13814..14383)
                     /gene="scpB"
                     /locus_tag="LP386_002329"
     CDS             complement(13814..14383)
                     /gene="scpB"
                     /locus_tag="LP386_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HBL1919540.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(14367..15164)
                     /locus_tag="LP386_002330"
     CDS             complement(14367..15164)
                     /locus_tag="LP386_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HBL1919541.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFGTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(15134..15505)
                     /locus_tag="LP386_002331"
     CDS             complement(15134..15505)
                     /locus_tag="LP386_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBL1919542.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(15524..16411)
                     /gene="xerD"
                     /locus_tag="LP386_002332"
     CDS             complement(15524..16411)
                     /gene="xerD"
                     /locus_tag="LP386_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HBL1919543.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
BASE COUNT         4645 a         3577 c         2798 g         5507 t
ORIGIN      
        1 aaaaattaaa taaaatacat gtgttttcta tgtatgacat acggattcgg aatctctgtc
       61 tcttatttat tccttttctg ctaggaaata aaaagaaaag cacttgtagc cctagagcca
      121 caagcgcttt ttcaactgtc ttatttaaca gcgtctttta atgctttacc tggtttgaat
      181 gcaggtactt tgctagctgg aatttcgatt tcttcaccag tttgtgggtt acgacctttg
      241 cgagctgcgc gttcgcgaac ttcaaagtta ccaaaaccga ttaattgaac tttttcgccg
      301 ttagctaaag catcttgaat agttgaaaat acagcatcta ctgctgcagt tgcatctttt
      361 ttagttaaat cagtagctga agcaactttt tcgattaatt ctgctttgtt tgccatggat
      421 agattcacct cctccacaag agatatgata gaaatatcat ttagttaaaa ctttctgagt
      481 ggtccagaag tttaaaaaga aatattgatt aacttcaata ttctgttatc acgatatcat
      541 atgaaccgct taatagcaag gtttttacca attttcacat gcttttttta gtcatagaaa
      601 cgtaacaaac gaaactgtct ttttcttttg aaaaaaaaac gtcgatatgg taaaatgcct
      661 attttctcct acgagggata attcggatgg acgtcccttc aaaagtaaat gcttttctga
      721 tttgattttc taagaaacgt tcataagaaa aatgcatcaa ttcctcttca ttgacaaaaa
      781 cgacaaatgt aggtggtttg acagcgactt gtgtagcata aaaaatcttc aggcgttttc
      841 ctttatctgt tggtgttgga ttgattgcta cagcatccat aatgatatca ttcaacacag
      901 ccgaagagat acgaagattc tggttcatac ttacttgttc gatcatttca ggcagacgtt
      961 ccaaccgttg tttagtcact gcagaaacaa aaacgattgg agcgtaatca agataccgga
     1021 attcatcacg aatctcttgt tcgaaatcac gcattgtatt ggtttctttc tttacaagat
     1081 cccatttatt cacgacgata ataattccac gaccagcttc atgggcgtaa cccgctactc
     1141 gcttgtcttg ttcccgaatc ccttcttcag cattcagtac catcaaaacg atatcagaac
     1201 ggtcaatggc acgcattgca cgcatcacgc tgtatttttc agtattttcg tatacttttc
     1261 cgcgtttacg cataccagct gtatctatca ttaagaattt ctgaccactt tcagaaacga
     1321 agtgggtgtc gattgcgtct cgggtcgttc cttcaatatc cgaaacaatt acacgttctt
     1381 ctcctaaaat cgcattgatc aaagaggatt taccaacatt tgggcgacca atcaaactaa
     1441 acttaatcgt gtcgtcgtcc tcttcttcag tctcttcaga gaaatacttc actgcttcat
     1501 ctaaaatatc accaatccct agtccatggc ttcctgaaac aggataagga tcgcctagcc
     1561 ctaaggaata aaattcatag atatcgtttc tcatttctgg attatctact ttattgactg
     1621 ctaaaatcac tggtttatta cttctgtata aaattttcgc aaccatctca tctgcgtctg
     1681 tcacgccttc gcgtccgctg actacacaaa tgattacatc tgcttcttca atcgcgattt
     1741 ctgcttgatg cttgatctga tccataaaag gttcatcgcc aagatcaatt ccgcctgtgt
     1801 cgatcacgct gaattctcga cctaaccatt caccttttgc ataaatacga tcacgagtta
     1861 ctccaggagt atcttcgaca atcgagatac gctcaccagc gatgcggtta aaaatcgtag
     1921 acttaccgac gttcgggcgg ccaacgattg caattgttgg atttgccata ttatttcctc
     1981 ctcacaagtt tccaatctca cttagtttaa cgaatgcatt gccaactttc aagcatagat
     2041 tgtcaattaa acgaagtatt tttattcctt attgaaatac taatcgcttt tcaaaagaaa
     2101 aactgagaca aaagcagctg ctttcatctc agtcacagat acaaaatcaa ttatttttca
     2161 gaatcatcgg ttgctttttc ttctacttct tctttcaacg catcacctaa aatgtctccc
     2221 atagtaaatc cagtattttc ttctggtaat tcataagact caacattttt tggttcttct
     2281 tctgaagctg gtttttcttc taaagctttg atactcaatg caatacgatg ttcttctgga
     2341 tggatctcta atactttcac tttcacttcg tcaccttcat gaagcacttc atgtggtgtc
     2401 gcaatatgtt tatgtgaaat ttgagagata tggactagcc cttctactcc agggaacact
     2461 tcaacaaagg caccgaagct tgtcaaacgt ttaactgttc cgtctaatac tgtgccaact
     2521 ggagcttttg tatcgatttc tgaccaaggt ccaggctgtg tgtctttgat tgacaaggaa
     2581 acacgttctt gttcaggatt gatagacaac actttgacat ttacatcatc attgacagcc
     2641 aatacatcac ttggttttgc tacatgacta tgtgaaatct ctgagacatg gactagaccg
     2701 tcaattccgc ctaggtcgac aaatgcgcca aaatcagtaa gacgtgcaac acgtccactg
     2761 agaacatctc cctcatggat agttgaaaga atttcttttt tcttttcttc tctttcgttt
     2821 tccactaccg ctttatgcga taagatcaaa cgattttctg atggttcgat ttcgatgatt
     2881 ttaaagctca atgttttgcc tttatagtct gaaaagtctg caacaaaatg atcttccacc
     2941 attgatgcag ggacaaaacc acgtacaccg acgtcaacga ctaaaccgcc tttgacaaca
     3001 tttgtaacag gtgcttcgat gaccttgccc tcttggaaat ctctttcgat atcttcccaa
     3061 acttttttag catctaaacg gcgttttgaa agtaggtagc tgccgttttc tttatctttg
     3121 ccgatcgtac tgataacgac taaatctaat acatcaccga cttttactac ttcgctgata
     3181 tcttctaccg gcaaagttga taattctttt gccggaacga ctccttcaac tccagcccct
     3241 tcgattccga caatcacttg tttgtcttca atgactaaaa cttcgccctt aacaacatcg
     3301 ccaactttta cttcttgtac gcttttcatt gcgtcttcca ttgactggtt gttctcttga
     3361 ttttgatcaa attctgtcat aacacttgtc ctcctaacca acattctgcc gtaagtacgg
     3421 tactgttttt agtttaattg attattcaaa aaaaataaag cgatttcgtt cgttttcctt
     3481 gaaaaaacaa ttgtttttca ttttttttct taatttaaaa aagaagataa ccttttttca
     3541 aaacaacagc ttttattgct gcaacgactt ctggaatcga tttgccagtc gtatcgatac
     3601 gaacagcatc ctctgcttgc ttcagcggag agacgtccct tgttgaatca taatggtctc
     3661 tttcctgtat ctctttcgtc agtgtttcaa gatcagtcgg aattcctttt tcttggttct
     3721 ctttgaaacg tctttctgca cgctcactta cgcttgctac taaaaagatt ttcacttctg
     3781 cattcggtaa tacagctgtc ccgatgtctc ttccgtccat gacaacgcca ccgcgttccc
     3841 ctatttttcg ttggacagca actaattctt ctctgacttt tccatgtgca gagacttcag
     3901 aaacagcttt tgtgacatct ggttgacgga tttctaaagt cacatctttt gatgctatga
     3961 atacatgctg tccatcttct tgttgcgaaa aagagatagg atactttttg atcagcgaaa
     4021 ctagcccttc ttcatctgaa aaagatacat tgttcgtaat agctaaataa gttactgcgc
     4081 gatacatggc accggtatct gtataaatat aattcaattc ttttgctaat atcttggcaa
     4141 cggtactttt cccagatgaa gcaggcccgt cgattgcaat actgatttgt gtcatgatat
     4201 aactcctttt tctcagaaaa aaagccgcaa agcgcggcta ttattattta attcttaatt
     4261 cttgaccagg gtaaagcata aagttgtttg gatctaagcc attcaattca aacaattgat
     4321 cagtggtgat ccctgcacgc tcagccactt gttttggacc ttcgcctgct tgaacagtcg
     4381 ttgttgaacc ggctgcagct gatgaagaag gtgttgtttc tgctgcattg ctgcttgaat
     4441 cccctgcttg ataagttgcc tcacttgagg aagtcggtgt tgtctctgct gcaatactgc
     4501 tttctgacgt tacacctgta tcttgagaca cagtagattc ttccgcgatt gtactagatt
     4561 ctactgttga agtctcagtt gactcctctt ttgttgtact tgtagaactt tctactactg
     4621 atgtcgaagt ttcagaagaa gttgctgctg ttgcattgtt gcttgatcca tttctgatcc
     4681 agaaataagc acctgctgga atagcgatac ataagaccag taaaatcaaa aatagcgaaa
     4741 gaaataatgt atttcctttc ttttgttgtc tctgagaact tcttgatgaa acttcatcat
     4801 ctgtatcgta gattggttgt tcccatggtt cttgtgtttc gttattttct gtagattgat
     4861 gtctatcttt tctgctcact gttttacctc ctaaactcta tcgtgtgtat tataccatag
     4921 gaaaaagtgt cttgtcctaa aaaatcaatg ttccatgttt tttttaaata aatttagtaa
     4981 aatcgtttcc caatgaagtt gttcagtctt agaaaaaagc ttcctctttg gcagaagttc
     5041 tgcttttgct ccatcaatat cacaacaatt ctgcggcttt tcggagagtt tttcgccaaa
     5101 ataagctaag atgaattttc tgcggcagtt ttcttcatta atatagcgaa gcatctgctg
     5161 caggcggaat tctttttctt tttcctgacg tttgagccgt tccacccaat tttctggttt
     5221 ttcagactgc tggatcagct ccatccattt tttttgcagc tcatcaaagg gagcttgctt
     5281 tgtggcatat tccaaataaa gctcaaaact ttgtcgctgt tctctagaaa gttgattaaa
     5341 gaaataatgg atacgttcat ccccactttg ataaaaaaga attgctgcac tttcttcctg
     5401 atctctgcct gctcgaccga tttcttgtac atagttttct agactgtctg gcaaatcata
     5461 atggaccaca taacggatat cagatttatc gatccccata ccaaatgcat tcgtagcaat
     5521 gagaaactgc agctgatttt ttacaaactg ctgttgaagt tgtcttcttt gagctgcatc
     5581 aagaccaccg tgatagtatc caactgtaaa acgttccctg aataaatgat acaatcgttc
     5641 gacttctttt tttgttgcac aataaatgat tgccgctcct tgtgctcttt ccatgaagtg
     5701 ttcaagttct tgttcttttt gctgcgtttt ccgaacaaaa agcgagatat tttgccgatt
     5761 gactgattgt ctgatctctt ttggtggtcg atcaaatagt acatgacgta tatctcttgc
     5821 tactaaatct gttgctgtcg ccgttagtgc cagtgtgacc gggtttccta aaagctttcg
     5881 gatttttcct aactgttgat attctggacg gaaatcaact ccccattgag acacgcaatg
     5941 agcctcatct actacatata acgcaatatt ttgttttttc agatgctcta aaagagaagg
     6001 attagtcaac atttcgggac tcaaaaacaa aaatttatat tgcgatagat gacggaggac
     6061 gtatcttctt tcagattgcg aaagtaaact attgaaagca gctactcgtt tctcccctcg
     6121 tttttgtaat tgcgtcactt gatcttccat tagagaaagc agcggtgaca cgatgatgac
     6181 cagaccttcc attaaatacc ccgtcaattg atagcaaagg ctttttcccg ttcctgtagg
     6241 caaaatagcg agagtatctt ctccatcaag caacgcctga ataatttctt cttggccggg
     6301 acgaaatgaa tcaaatccaa aatatttttt taattcattt attaacattc tgtatcgctt
     6361 cctttctcaa tagatagatt tgatacaaac gaaattctcc ataatctaat tgtccatcta
     6421 cattccattc gctaaagcgc cactctcgca cggaatcctt atttggttcc aaacgttcga
     6481 ttgtttctgc agagagaatc cactcgtatg gaaaatcatc aaaaaacaag gcccactcaa
     6541 taagatgatc tgttactgtt cctcttttta aatgacggat tgccatgatc tggtcaattg
     6601 tctgaccatt cataaacatc tgcttggtga tcatcatgct ttgattgaaa ttttgctgta
     6661 ataatgaatc gatcaaagcg tgccaaagcg aatctggccg tttttcgatt tgtgctaaca
     6721 aaaggtggat acatctgctt tgttgcagat aaacctctga ctcatcattg ttttttgcca
     6781 gctgataagg aagcagccct gttcgctcat ttccagataa ttggttagct aaaaaatctg
     6841 ctgcttcttc tggtatctcc gaaaacagct gcaccaaact ctcatacgca gtatcaatca
     6901 aaatttcacg tggcaattgg ctttcactaa gccatttttt tagttggaaa gtataaaaag
     6961 gacttgtctc tgctggaaga tagtcttgaa tacccgttgc cagattagaa attacttgaa
     7021 cagcaaattt aatgagccgc caactagttt cccctgttct gccatagcgg tcaaaacgca
     7081 aaccagtatg ttctatttga tgttcggaca acatatcagc ccctgcaggc gttagctttg
     7141 cttcattttc atttatttcg atccaacctt gctgcgcaat tttttgcaaa atttgataaa
     7201 acttatcctg cttcaattct ggaaaactgt tatggataaa caaaagttcg tgggtaaatc
     7261 cataaataag tactgaagtc gttcgttttc ccacaaggag ttggtaaaga gaactaatcc
     7321 gcagcttgtg tcctgatgaa aatagcgata aaataaaaac aatcatatta ttctccttaa
     7381 gttaggatgg ttagaaatgt cactactatg taaacttgta cctgaacgct gtattgcatg
     7441 cggtctttgt caaatcgaag cgccagatat tttcgattat gatgaagaag gaatcgtttt
     7501 atttgcccaa gaaccagagg ctcatcaaca gttcgtgatg ccggaagaag aaacatatgt
     7561 aaaaaaagcg tatcaaaaat gtccagttcg agcgatttta ttagaaaata aaatataaat
     7621 ataaacgaaa ctttaaaaac gtacactaag ttctctaaac ttgaaaataa gccgggatct
     7681 gtttctcttg ttccgtgaaa tcccgactta ttttgaaaga ttcatttgct atctatagtt
     7741 aattgactag ttttttcacg gaccctatag gacccattta tattatttca actttttcag
     7801 ccagttttcc aatgtattga cgatcacagt ttgctggtct gcgttagaaa tttctgcctc
     7861 tccatctcct ttttgctcac catagctgcc aaaacctcca tgatttccgc cattgattga
     7921 tacatactct gttctttccg gtaaatactg cttagcttct tgataagctt cctgattcaa
     7981 tactttatct tttgtcgccg tgatcgataa aacaggaaca gctgattctg tcaatgttcc
     8041 ttttttgtcg ggataacttg ccatgaagaa tacccctttt aaatgtttgt ctgaatgatt
     8101 cttattgaca taacgacttg ccattacgcc acctaatgaa tggccaccga tcacataatc
     8161 ggaatttgga aaatcttctt tgaccttatc cgctttgttt ccgcccatca ctgctagatc
     8221 aagtggcatt ttgacaatag cgactgaaaa gccgtttttt gctaaatctt gcgcccaaat
     8281 actataactt tctggctcta cgagagcacc aggataaaaa ataagtaatg gagactttcc
     8341 atgattcttt ttctctcctt caaaaaataa gtaatcttct ttgttttttc cttcttttac
     8401 caacacttgc gcttctgacg atggttcgta cgtattttgc tgtatatagt aataaccggc
     8461 tccaccgagt aatcctaaaa tgatgactaa gccaattagt attcgtctaa atattttcac
     8521 tttctcccac cttttctatc tgagtgaccc ctttttctta atcaagtatg attatacctt
     8581 aaaaaaataa gagagaaatg caaactttcc agcatcaaat aaaaaaagac ggaatatcca
     8641 tttgaatatc cgcccttttt gtatgtttat ttttatttag cacataaacg atacacagct
     8701 tctgcataaa tttccattgc tttatacata ctacttaatt cccatcgttc attcgcctgg
     8761 tgcataaagt caggagtatc agggaacatc gcaccgaatg ccacacactg gttcatcgta
     8821 cgagcaaaag tagcgccgcc tgatacaaac ggttcagtca tgtctccagt aatatcgcga
     8881 tatgtcccca atagattttt cactaactca ctgtctagtg gcacgtataa tgaatcaagg
     8941 aagtcaaatt cttcataagt caacccatat ttttctgctg ttttagttaa tttagctact
     9001 aaatcatctt tcttgaatgt aacagggatt ctcatatcta caccgatttt tgtttgttct
     9061 ggtgtgattt ccaaacttgc aaagttcatc gttagctcgc cggattgttc atcttctgtt
     9121 ttgcccacga cagcttcacc agttgcattt tcttgaacta attttcctaa gaaattgatt
     9181 gggccaaaat caaatacttc tgaaagagca attgccagac gagaaatagc attcactcct
     9241 tgtgctgcat ctttcgcgtg gatactttta ccaagaacga cgatgccttc accttgttct
     9301 tcgaaatcga attcgtgttt tttcaatgct tcttttactt cagaaagctt ttctccagag
     9361 taaggagctg catcaggaac aacattcaac gctcctccag cttttacaga aaactcgttc
     9421 gttcctggtc ctgtcaagta agcttgcaat aagccttttt ctgcataaat taaaggaaat
     9481 tcagcatctg gcgcaaatcc ttgcgtaatt ccttcttctt tttcgttata tttttctaaa
     9541 caacgccata aattttcttc atctgtacca aagataaaac gaatacgtgt cttgaattcc
     9601 acgccagcat caatcaaagc tttgacggca tacattgccg caatagaagg acctttgtca
     9661 tcttgggatc cgcgaccaac taaccagccg tcttttatag ttggatcgaa tggttttgtt
     9721 tcccaattat tttcgtcccc tgctggaaca acgtccatat gacacaagat accgaataat
     9781 tcatctccag agccaatctc tgaataaccg taatagcctt ctggatcttt aaatgttcta
     9841 aatcctagct tttcactgat ttccaatact ttatccaaag cttcaatcac ttttttaccg
     9901 aagggatgtc cttgtcctga atctgcttca tctagtacgg aaggaattcg gatcaattcg
     9961 ctcaatgatt ctaatgcttg ttcatgatgt tgttctgtca caaatttttt catgatatta
    10021 tcctcctaat atgttaaaaa gggtcatgtc aaattcctcc gacacaacct cttcttctca
    10081 aataatgacg ttttaagcct gctccatcag caagcagaat gttcttaaca aatgatgaaa
    10141 gaaaaaacac tcactgaatg gagctattga cttgtccacg tgcttatcga tagccgttta
    10201 tcggtttctt cattcttatg atagaccttg tacctgtatt tgtctaggtt tagaacattg
    10261 ctgctacacc taggatcaca cagatggcta caaataatat cgcaattaat ttaccggtaa
    10321 atttccacca cactgaaaca tcgaaacgag caattgctac agcacccatt acgatagcag
    10381 atgttggtgt aattaagttt actaaaccag atgcagattg ataagcagtg attactaaat
    10441 ccttaccgac gccggcaaat tcacccatag gtcccatgat tcccattgtt gcagcagcta
    10501 agccggaagt tgaaggaatc aagaatgaca tagggatata gaaaataaat gtaataatga
    10561 tgaatacact tgaagataat gaacttaatc cttgttcgcc ccaatgtaag atggtgtctg
    10621 tgattaatcc attgttcata accacttgga taccacgagc aacagctact acgattgcta
    10681 caccgatcaa atcagaagca ccagctaaaa attcagagac aaattcagac tctttcatgc
    10741 cataagtgat tgctactacg atggacatta ctaagaataa catagtaatt tctgggaagt
    10801 accagtcacc taatggaagc atgcttttac ctagaaccgt acctagtacc ggaaggtttg
    10861 ttaaccagtt tgtcaatgat tcaaaaatcg tgaaattcgc attcaaggtt gtccaaggaa
    10921 tcaaactgat gatcatgata ccaaaagtaa taaagaacaa tacattaaca tgtttttgtt
    10981 ttttcgtgat tacttcttga cgaccgattg cttcaatatc gaaatgcttc atatcttctt
    11041 tacgttggtt gtatactaat gattttgttg gatctttttc gatctttgat gcataacgat
    11101 acacatatac aatagaaata gctaacaaaa taacgaacat caagaatcga agaccaatac
    11161 cttcacccat cgaaatccca acagcttgtg aagctacgcc tgttgcaaaa ggatttaccg
    11221 ttgaagctag acagcctact tgagacccta ctaatacgat tgctacagct actactgtat
    11281 caaagcctac agccatcatg actgggatca gtaaagcata gaatggaatc gtttcttctg
    11341 ccattccgta agtagagccg cctaatgcaa ataacagcat caatactgga ataagcattt
    11401 tttcttttcc tttgaatttc ttcacaactg aagcaatccc ggcatctagt gcccctgttt
    11461 tgttgataat acctaaaaat ccaccaacaa ccaaaatgaa gaaagagatt gggattgcag
    11521 caggtgtttc tttagttagc tcccccgctg gtacacctag catcccattg attggcgcca
    11581 tgaaaatatc ccacagccct tgaggatttt gttgtactcg ttcatatgat ccagcgacga
    11641 tgttgcctgc atcgtctaca ctatagtgcc cagctggtat aaaccaagta agtacagcga
    11701 ttactgcaat aataataaat aagaccgtat acgctgaagg catttgaaat tttttctttt
    11761 ttgtttgttc catcttcttc ttcctttctt ttccgttaga gacaacaatt ttggctctaa
    11821 tgttatttta tcaaaaagag tatcagaaca aaaataataa cacgcatttt gtaaaacttt
    11881 tgttcaaaaa gttcgttttt ccctattccc tcctcttttt tcaggttttt aaagctttct
    11941 tctttttcat tgtagcgttt cctttttttt ataaacaaac attttcgtct tttaaaagga
    12001 gaagaatttc acatttgcaa agaattgatt gatttttatg cataaatcaa aaaaatactc
    12061 aaaacaaaca aataaaacgt ttacattatt gcatgtcttg tatttttttc caaaaaaaaa
    12121 gaccaagaaa tttcttgatc tttttgatat ttatttgact gctgtatgac gttgttcgaa
    12181 ctgatgttgt tttcgactta accatggaag aagttgcgca tgcagcacta aaaagacagc
    12241 actcacgatg aatcctttga tcaagttgaa aggaacgatc ccaatcagta catagtttgc
    12301 taaagacatg cccagcatct gtgttgcgtt cagccctaaa aacattaagt aaagaggcgt
    12361 aataacgaaa taatttgcga tactcataaa aatagttaga gcgatggttc ctgtaatgac
    12421 acctaaaaat ttgtttcttc ctttatgctg tttctttaca ctaaagaaat aataaatcgg
    12481 gaatgtaaag atcgttgttg ataagaaact agcagtgtct cctaccaaat tatccggaga
    12541 aaaacctgta gtcagcagat gtaatactga acgcaagaac gctgttgcaa ctccggccgc
    12601 tggaccgaat aagaacatgc tgatcaatac cgagatatca ctaaaatcga tcttcaaaaa
    12661 actaaaagcc ggcatgatcg gaaaagcaaa atactgtaaa actaatgcga tcgcagcaaa
    12721 catcgctact gcaaccattt tctgtacacg ggtgttcttc atttgaaatc ctcctgttag
    12781 gactcctctt cagcgaactt tttgacgttt ctctccaaat gaaaaaactc tattttccag
    12841 ggaaaataga gttagagtta tttgatcaag cgtcgtcaaa taagctctat cttctttatc
    12901 cagactatac tgtcggtatc ggaatttcac cgattcagct atttttttgc aaaataggtc
    12961 gtggactata accaccggtc gggaatttca ccctgcccct gaagacgaac cttatataat
    13021 ttttgtttac atattcatta tacatatcta ttcaaaaaac gcaacatcta acacttataa
    13081 aaagtaagtg ttcattttga gtggttcagc aaactgctga cttctttttt gttcagttca
    13141 cggtaatccc caggacgtag gccttgtaaa gtcagatctc cgtatttttc acgttttagt
    13201 ttttgcacag gaagaccaac tgcttgaagc atatttttca cttgatgatt acgtccttcg
    13261 tggatcgtca attccacgat actgtggttt gtcttaggat ccactgataa aatttggaat
    13321 ttagctggag atgtttttcg tccttcgatc tttattcctt ttgtcaaagg tgcaagcatc
    13381 gattttgtag cgatcccttt tacctttgca acgtaaactt tatccacttc atgttttgga
    13441 tgtgtcaggc gctgagcaaa atctccatca tttgtcagta gcaagatccc cgaagtatcg
    13501 taatccagtc gacctacagg atagatacgt tcttttacca tcggcaaaag atccgtaaca
    13561 acttttcttc ctttgtcatc tgcaacagca gaaataactc ctttaggttt gtacaataaa
    13621 tagtaaccgt attcttcttg ataaattggg acttcatcca cttccacagt gtcatgtttc
    13681 ccaactttta tccctaattc ccttacaact tgtccgttta cttttacacg tcctgcaagg
    13741 atgaattctt ctgcttttcg acgagaagtg atgccagcgt gggcaattac tttctgcaat
    13801 ctctccatta caattattct cctttattca ttccatcaaa gaatagatct ggtgacacgt
    13861 cttcttcaag tgaaatttcc atttcttgtg tatcaggcag ttcttctaat gatttcaaac
    13921 caaaataatc taagaagtag ccagttgttc catataatat cggccgacct ggtccttcta
    13981 ctctaccttt ttcttcaatc agtttatggg cagctagacg ctgtaccgct cctgaaacct
    14041 gaactcctcg aatctgctcg atttcagctc ttgtgattgg ctgtttataa gcgatgattg
    14101 ctaaggtttc gacggcggct tgagataatg tgtttgatgt cccttgcgca tatcgcttaa
    14161 gtaagggagc cagctctttt ttagtcgtta atacataatg gctttccgtt tcaaaaatat
    14221 gcaaagctga gtgcgagttt tgagtgtaag attcttttaa ttctttcact aaacttgtga
    14281 cttctgcttc gctgagattt aacagtccgc ttaattcttc attactgatc ccttcctcgc
    14341 caacaataaa aagaagggct tcaagttcac ttaatttcgt catgttcggt atctcctact
    14401 gctggataaa gcataattga ttcatagttt tctttttgtt gcgcaatgat ctgccctttt
    14461 ttcatcaatt ctagcaaagc cataaaagta gtgacaactt cacttttaga aggtgactca
    14521 aaaaaagaat cgaaagtaca gccatgcgca tttcttttta tacgctcttc gataaatacc
    14581 attcgttctt cgatcgttgt gtcatcgggc gtgatcgttt tttccacttt ttgagaaaat
    14641 ttcttacgtt ctaagatttt ctgcatggca cggatcaaat cgattttttt gacttgtcct
    14701 cgcttcaacg gcttttcagc atccgctaac ccatcgatgt tcataggttc ttttgtgtaa
    14761 taaagacttc gttcctctgc tttttctgtc agtctttcag ctgcatattt atatttacgg
    14821 tattctaaaa gctgagtgac caattcttct cgaggatctt cttcccataa ttcttcatcg
    14881 tctgtgccga attcttggac aggaagcaat gtcttgcttt tgattgccat caatgtagca
    14941 gccatcacta agtattctcc tgcaacagct agctcgagtg ttttcattgt atggatataa
    15001 ttcatatatt gctccgtgat cgtagcgatc ggtatatcat atatatcgat ttccatttgc
    15061 tgaatcagat gaagcagcag atcgagagga ccctcgaata catctaattt aatattgatc
    15121 tccgtcaact cattcactct ttcttctttt tctttgctag ccattttcca atgtaaggct
    15181 ctgtgatttc agttgcacgg atggagacat ccgggtactt ttcctgtaat tcatctaaca
    15241 tttgaaagcc catattctca ccgcgataag acggattcaa agaaatgtca tggatgatca
    15301 gctgatcgtt cgttgcccag taaataccaa taatcccttg aatgttggtt gaaccttctg
    15361 gcgtaaagaa aaaaagttca taatcgtctt cagattcgta cgtatcaatc tccttcaaca
    15421 aagaagtttt acctgtcagt ttcttatgga aactcaatag tcccatagca attttacggt
    15481 tttctttccg gtaatgtgtt aacatcttct caccttccta tgactaagcc cttggaaaat
    15541 gctgcttata aacatccgtc attcttttct tcgtgatatg tgtataaatc tgagtcgtag
    15601 agatatccgc gtgacctaac aattcctgta ctgtccgcaa atcagctcca ttttctagca
    15661 gatgtgtggc aaagctatgc cgcagcgtat gtggtgttac ttctttgtaa atcccagcct
    15721 ctcgtactaa ctgcttcaga tttttccaga ttccttgccg agaaagacct ttcccatgat
    15781 tattgacaaa tacatgcatt tcagatgcgt cctttacaag taatggacgt gcttcgtcta
    15841 agtagcgttc cagccattgg atcgcataat cacctaaagg aatgatccgc tctttatctc
    15901 cttttccaac tgtctgtacc agtccaagag aaagatgaag atctcccaat ttcaatccaa
    15961 tcaattcact gacgcgcatc ccagtagcat acatgacttc caagattgca cgatctctta
    16021 tccctaacgt ttttgtcgta tcaggtgctt caatcagctt ttctacttct gtcagagtca
    16081 atgtacttgg taatttctgt gctttcttcg gcgtatcgat atgttgcatc ggatcatgat
    16141 cagtgatacg ctcttgccgt aaaaactgat ggaatcttct gagacttgag atcatccgag
    16201 taacagttgc tgtcgctttt ttttcttcat gcaacttctc cagaaaacgg atgactaaaa
    16261 agcgatcgac atcctgccat gaagcaattt tctgctcctg tagaaaatgc aagtactgtt
    16321 ccaaatcacg ttcatagctt tgtcgtgtat tggcggacaa tccccgttca atattcaagt
    16381 agtggagata atcgttgatt tgctctttca taataatccc cctcatgcct ctctatcata
    16441 tcagataccg cttcattctg atagtctttt tccataatct gagcaaagaa aaagccgtct
    16501 agacactcag acggactggt ttctttt
//
LOCUS       DAFEKH010000062        15793 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.065, whole genome shotgun sequence.
ACCESSION   DAFEKH010000062
VERSION     DAFEKH010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15793
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.065"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..1040
                     /locus_tag="LP386_002333"
     CDS             <1..1040
                     /locus_tag="LP386_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBL1919544.1"
                     /translation="TNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKYNPEGQ
                     KVTTDLNKEPDASEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSSDEV
                     EVDVTVTDTRSDADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVS
                     TAGNKKGTVVVTYPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPNAEV
                     TVTLPDGSQYHGTADKNGNFTVKVPKLEAGTKVRVTATDESGNTSEPTNVVVSSNKKD
                     SGKNGSKGSKTDNQDGNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGTLGL
                     LGYKNRKKENE"
     gene            1174..2517
                     /locus_tag="LP386_002334"
     CDS             1174..2517
                     /locus_tag="LP386_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL1919545.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKLILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDNTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GKEKIEKIVTTRDNKYAMDMVIQAIGFLSHSPIGKKEFLRDVSGAYLTDEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINDQSFTPSGSQFTNGFSIFG
                     YNFYAAGLNLKTARLLSEAIDYIEIEDYIRPIFSKTNNIVKLRISFEKKAKRIVGVQF
                     YSQEDLSGLLTMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNSGA"
     gene            2629..4032
                     /locus_tag="LP386_002335"
     CDS             2629..4032
                     /locus_tag="LP386_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HBL1919546.1"
                     /translation="MKKSLKLASAVLLMSHLLIATPFHVLASENSTYKIAKERTKTTE
                     MSNSDVTAEGSEFSTTSSSESSTTLNAESSTTSSSESSMTSNAESSTTSSSESSTISS
                     TESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFSTSQQIESTETFQSQPV
                     LSGNEEIHFDKNESVENFIMKIGDSARKIGQKYDLYASVMIAQAILESASGQSQLAQA
                     PNYNLFGIKGTYNGSFVIMVTNEDLGNGTLYKTQSKFRVYENYEESFEDYAKLLTKGI
                     SGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNGLIKTYDLTDYDKEVQGP
                     QMNKNGYQIPIHNYSISSLFGNRGDEFHRGLDMAAAQGEPIHAVKAGKVIKAEFHYSW
                     GNYVVIQHEDGSTALYAHQQQYLVKTGDNVVQGQMIGYVGSTGNSTGPHLHLEICKDS
                     SLSQSMLVDPKTLLFGN"
     gene            4450..4665
                     /locus_tag="LP386_002336"
     CDS             4450..4665
                     /locus_tag="LP386_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919547.1"
                     /translation="MNQEIADIKLIKEVLQESTANAIASGSGISLSTAKKLKSGERNV
                     EKLNLSDAIKITEFAIKNRHVKIEIWK"
     gene            complement(4751..5662)
                     /locus_tag="LP386_002337"
     CDS             complement(4751..5662)
                     /locus_tag="LP386_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL1919548.1"
                     /translation="MKIKIERNQKEKSPKKNKERVISVGKHRKMVLALWLLLSCSLAF
                     GIYRNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWRNNKEAIEKRMSNL
                     EQYLTENGLALSQDMVRADIPTSSEVQSIKILDVEKHSEEFIVSFLVEQQITEGKKTQ
                     SISSAYRVTIFEDENGSHIVTSLPTMIAKPEKAKYESKQIGIESDIDAKTTEEVTDFL
                     ETFFKLYPSASEKELEYYVENKAVQPINSNLKLVELVNPTFKLKGKEIQGEIFVKYLN
                     NTTKVSNIFEFTLTLQKVKNWKIIDIG"
     gene            complement(5681..6685)
                     /locus_tag="LP386_002338"
     CDS             complement(5681..6685)
                     /locus_tag="LP386_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBL1919549.1"
                     /translation="MNVKKLSIISLTILTLSFMVVLMCVGLLFGEDSEGSNSSGASSG
                     GSNVSEEVLKHRAMVEKYAKESNISEYVLILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVAKNGKKHNFALA
                     ESFSKEKSSGQKVDYPNPIAIKKNGGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGASPETGFDCSGLTQWCYAKVGLKLPRVAQDQYNAMTHIDVKDA
                     KPGDLVFFHSTYDTGTYVTHVGIYAGENRMFHAGDPVGWTNLTESYWQQHLIGAGRYK
                     "
     gene            complement(6682..8805)
                     /locus_tag="LP386_002339"
     CDS             complement(6682..8805)
                     /locus_tag="LP386_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBL1919550.1"
                     /translation="MKKKLLRIVGIIAISLCTILLLLSLIGTVAEATGLVDDTVKSGN
                     LYSQYSLDNYQLDFFVDSSWGWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQVSGFYFGFLLLMILALGVYVAYI
                     GLLKREATKAVRAVINFVTIFLLSGSFIAYAPTYITKINNFSSDVSEAALSLGTELVV
                     PNSESKGKDSVDLIRDSLFSIQVRQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRIMRKPHMLMNRKLR
                     QLNRNVIRTLAFGGGAAVGHKLEKEQSKSKFKPSGSSLRKNSRLPNDHEVPSDSTKEN
                     PVSNNKKQSRMNLAGRKMGKVLDTQALVKDKTKQVRDQVRNTPTNLKYNFHKGIEKTK
                     KAPKEFKRGLVQEKANRAELREKQRQHRDEKMAEKRKVLNETGNRHKKRRENVSIKPE
                     RQPQKDRAPKKEAPKQIVRVNPNPEIKRKLSSHEIVSKRISQPSSKKNSFQQVKQRST
                     LPKRTNQKVQKRMNPRPKSRSGEKK"
     gene            complement(8810..10090)
                     /locus_tag="LP386_002340"
     CDS             complement(8810..10090)
                     /locus_tag="LP386_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL1919551.1"
                     /translation="MHVRCGAGENLEITSKGYLSLFTSDFLAGLGFGATQMLGELEGI
                     YFGYNVDTGRNVYLKPALASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFG
                     GQAVIVDPKGERGSWKETLPEIASEINILNLTSKPENQGLLDPYVIMKKKKDSESLAI
                     DILTFLTGISSRDGEKFPVLRKAIRTVTQSNQRGLLQVITELRNDGTPVAENIADHIE
                     SFTDYDFAHLLFSDGSITQSISLEKQLNIIQVADLVLPDAETTFEEYTTMELLSVSML
                     IVISTFALDFIHSNREIFKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQ
                     NSDDLLDERLKNNIGLKFAFRSTDIHEIKKTLEFFGLDQEDESNQKRLRDLENGQCLM
                     QDLYGRVGVVQVHPVFEELFHAFDTRPPVQKRME"
     gene            complement(10130..11896)
                     /gene="ltrA"
                     /locus_tag="LP386_002341"
     CDS             complement(10130..11896)
                     /gene="ltrA"
                     /locus_tag="LP386_002341"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBL1919552.1"
                     /translation="MQETFDWLYERSSKQATKGIDLYKIIMSEENILLAYRIIKSNTG
                     SKTSGIDNQTISDFKFQNKQKFVNDIRKTIENYQPQPVRRVNIPKSNGKTRPLGIPTM
                     KDRLIQQMFKQVLEPICEAKFFKHSYGFRPNRSTEHAIARCNFIAHKCKCHHVVDVDI
                     KGFFDNVHHGKLIKQLYTIGIKDRRVLAIISKMLKVTVAGQGTSTSGVPQGGVLSTLL
                     SNVVLNDLDWWIANQWETFQTKRKYSSVDNMHHALVKSKLKKMHIVRYCDDFKIFTTN
                     HKHAVKIYHAVKGYIKQRLNLDISPDKSKITNLRRNYSEFLGFELKVIKQKKQQYVTV
                     SRVSKKSKSRIKKEIREKIKAIQKSPTRKTVNQYNQYVRGIQNYYQKATLINHDFSSI
                     YYSCLPALYNRLKPFGKYEIPRSPPITYKKFYPLTKRTFCVRKNYLFPLDSVKWKRLE
                     FFKPHINNYTQDGRLAKLRKLKPSVYSELVTLSTMETDESLEYLDNRLSRYSMQNGKC
                     SVTGIFLRTQDVHCHHIIPRKFGGTDEFDNLVIIHKWVHRLIHAKTKETIKEYLQLLQ
                     LTNKQMKKLNKYRLECNLTEFH"
     gene            complement(12640..13869)
                     /locus_tag="LP386_002342"
                     /pseudo
     CDS             complement(12640..13869)
                     /locus_tag="LP386_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP/GTP-binding protein"
     gene            complement(13856..14245)
                     /locus_tag="LP386_002343"
     CDS             complement(13856..14245)
                     /locus_tag="LP386_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL1919553.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHMPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(14328..15053)
                     /locus_tag="LP386_002344"
     CDS             complement(14328..15053)
                     /locus_tag="LP386_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919554.1"
                     /translation="MLEVMIIMNFDFDLKSFIDIFVPVLTSFAVCFITLFFTNKQHKK
                     AMKQQERQHEESLDLSKQQYADEKQRNEEQDRLSYYPYLKLIPKISEHRFAGKMVKSD
                     ENDVFKLPFELINEGLGMAFSIDFVYLEETINTNDHEVNLLSLLSAQKHIDDSLDALG
                     VSAPIDTDILRVGKKTEFELYWMKYNNEVMSIPKYSVSKWEIKIRFSDFQDRIYQQRY
                     TFITSAGYQEIHRLWSDKPQLID"
     gene            complement(15102..15605)
                     /locus_tag="LP386_002345"
     CDS             complement(15102..15605)
                     /locus_tag="LP386_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBL1919555.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFSPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPIGEVALEIQHAFFNSFEEMVEH
                     VDDIICYPDCNDMSDVAYYLIEETGAFGEVPTHLQNYIDYEAYGRDLELEGNYLVTNR
                     GTFEFIG"
     gene            complement(15617..>15793)
                     /locus_tag="LP386_002346"
     CDS             complement(15617..>15793)
                     /locus_tag="LP386_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919556.1"
                     /translation="QSLVLLAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGV
                     KDVLLNLFNRIVGA"
BASE COUNT         5050 a         2960 c         2683 g         5100 t
ORIGIN      
        1 ataccaacac accaggcaat tacgaaggtg tcattgaagt aacgtatcca gacggtacga
       61 aagatacagt gaaagttcca gtagaagtga cagacaatcg ttctaatgca gataaataca
      121 atcctgaagg acaaaaagtg acgacagact taaataaaga gccagatgca tctgagggaa
      181 ttaagaacaa agaagattta ccaaaaggaa ctacttatgc ttggaaagag aaagtagatg
      241 ttagcacagc tggaaacaaa aaaggtacta ttgtagtgac atatccagat ggatcatctg
      301 atgaagttga agtagacgtt acagtgacag atactcgttc cgatgcagat aaatacaatc
      361 ctgaaggaca aaaagtgacg acagacttaa ataaagagcc agatgcatct gagggaatta
      421 agaacaaaga agatttacca aaaggaacta cttatacttg gaaagaaaaa gtagatgtta
      481 gtacagctgg aaacaaaaaa ggcactgttg tagtaacata tccagatgga tctaaagaag
      541 aagtagaagt tactatttct gtagtagata aaaaagcacc gaataaacct caagttgatc
      601 ctattacaga gggtgaccaa attgttactg gtaaaactga accaaatgca gaggtaacag
      661 ttacattacc agacggaagt caataccatg ggacagctga taagaatggt aattttacag
      721 ttaaagttcc taaattagag gcagggacaa aagtgagagt aactgcaacg gatgaatctg
      781 gtaatactag tgaacctact aatgtagttg tttcttccaa caaaaaagac agtggaaaaa
      841 acggtagtaa aggtagtaag acggacaatc aagatggcaa tagcaatcaa gacaaaaata
      901 gaggcaaaag ccagtcctca aaagtttttc ctaagacggg agagagtgac agtaatatct
      961 ttactattag cggtggttta atactgttag gaacgttagg attattaggg tataaaaatc
     1021 gaaaaaaaga gaatgaatag aaaatcaatt tcttaagtct tctctgagaa gaggaagaat
     1081 ctttttcttc ctctttttgc ttttttatga tgggaaataa gtgttagtta aagatgaata
     1141 tactttttat agaaaggaaa agaatgtaat taagtggaaa aaatagtaat tattggttca
     1201 aaccattcag ggctagccgc agctcgattt ctaaacttaa gcgattcaaa ttatgaagtt
     1261 attctaatcg ataaaaaatc agaaattagt tacttggaat gtgggacatc gttatttata
     1321 aaaggagaag taagtaattt agaagatctt ttttatcaaa atagaatgac actaaattct
     1381 gagataaaaa agttatttct agagacagaa gttgacaaaa ttgatattca aaataaaaag
     1441 attagttgtg taaaaaaaga tggcacaaga ttttcccaag aatatgacaa acttatatta
     1501 gctacaggtt caaagcaaat tatgttagat ataccgggga ataatttagc taatattttt
     1561 tcgataaaga attttccaaa tgccaaagag attttcaaag ctttagatga taatactatt
     1621 aaaaaagtag gtattattgg agcaggatat attggagttg aaattgctga agctataaga
     1681 aaaagaggga aagaagtata tcttttcgat gttgcagata gagtgttgtc gacctattac
     1741 gaccgtagtt tttcagataa agttgaagaa atactatcaa aaaacgggat acatctttgt
     1801 ctatcagaaa gtcctaaaaa gtatttagga aaagaaaaga ttgaaaaaat agtgactaca
     1861 agagataaca aatacgctat ggatatggtc atacaagcta taggattcct atctcatagt
     1921 ccaataggaa aaaaggagtt cttgagagat gttagtggag catatctaac ggatgaatac
     1981 caacaaacaa atataaaaga catatatgct attggagatt gtgctacaac tttttttaca
     2041 tccattaata gaagtagcgt tgatttttct atctctaatg ctctaagaac ggcttatatt
     2101 gcaactcaac atattaacga tcaaagtttt acaccttcgg ggtctcaatt cacaaatggc
     2161 ttttctatat ttggttacaa tttttatgca gcaggtttga atttaaaaac agcacgctta
     2221 ttaagcgagg ctatagatta tatagaaata gaagattata ttagaccgat tttttctaaa
     2281 acaaacaata ttgtaaaatt aagaattagt tttgaaaaaa aagcaaagag aatagtaggt
     2341 gtacaatttt atagtcaaga agatctatct ggattattga caatgttctc tcttgctata
     2401 gaagaacaaa ttacattaga caaattgaaa atgttagatt atttatttca tcctagtttt
     2461 agtcaaccct ataattttat tttaaaggca gtaacaggat taaatagtgg agcataatcg
     2521 ttattaaatg aaatcaagaa atatactgta ttactcaatt cattgaaaat atttgtcata
     2581 ttttttaata gaaaacacta ttaaagaaaa aaaagagagg taaatcaaat gaaaaaatct
     2641 ttaaaacttg catcagcagt tctattaatg tcccatctcc ttatagcaac acctttccat
     2701 gtgttggcaa gcgaaaattc aacatacaaa attgcaaaag aaagaaccaa gacgactgaa
     2761 atgagtaatt ccgatgtaac agcagagggt agtgaatttt caacaacttc atcaagtgaa
     2821 agtagtacga ctttaaatgc tgagtcttca acaacttcat caagtgaaag tagtatgact
     2881 tcaaatgccg agtcttcaac aacttcatca agtgaaagta gtacgatttc aagtaccgaa
     2941 tcttcaacaa cttcaagtag tacaagtgaa ataacttctt cgaaagttac aaagccaaac
     3001 catatagagt cttcaaaaaa ggaagcgcca aaaacggaag gacaaacaaa aactttttcg
     3061 acatcacagc aaatagaatc aacagaaact ttccaatcac aaccagtact atctggtaat
     3121 gaagaaattc attttgacaa aaatgagtct gtagaaaatt ttattatgaa aattggtgat
     3181 tctgcgagaa aaattggtca gaaatatgat ttatatgctt ctgttatgat tgcacaagca
     3241 atcttagaat ctgccagtgg tcaaagccaa ttagctcagg caccgaatta caatttattt
     3301 gggataaaag gaacttataa tggaagcttt gtcataatgg taacaaacga agatttgggt
     3361 aatggaacgc tttataagac tcaatcgaaa tttagagtgt atgaaaacta tgaggaaagt
     3421 tttgaagatt atgccaaatt attaactaag ggaattagtg gaaataaaga tttttatgcc
     3481 ggagcattaa aagctaatag taaaacatat cgagaagcaa ctaaattcct tacaggacgg
     3541 tatgcaacag atactcaata ctatttaaag ctaaatggat taattaaaac ctatgattta
     3601 actgactatg acaaagaagt tcaaggacca caaatgaata agaacggata tcaaatacct
     3661 attcataatt attcaatatc tagtttgttt ggaaatcgtg gagatgagtt ccatcgagga
     3721 cttgatatgg cagctgcaca aggtgaaccg attcatgcag ttaaagctgg taaagttatt
     3781 aaagcagagt ttcactattc ttggggaaat tacgttgtta tacaacacga agatggatca
     3841 acagcgttat atgctcacca acaacaatac ttagtaaaaa ctggagacaa cgttgtgcaa
     3901 ggacaaatga ttggctatgt aggaagtact gggaatagta caggaccaca cctccatttg
     3961 gaaatttgca aagatagtag tctttctcaa agcatgttag ttgatccgaa aaccttatta
     4021 tttgggaact aaaaagaaaa agagcatttt attagaagta tggattaggg aatatagtag
     4081 tagtgggctc taaagattat gaaatcttta agagctcttt ttaagacgat tgtttaaaac
     4141 gaattaacca agtaggagct ttcctagaat ttataaaatt atagtttctt gtatgacatg
     4201 tatatagcat gctaaaatac caataaataa ggtttaagat aaacgcaaaa agtcgaaaaa
     4261 ttaacactta ttttgtgata ttaattttaa tttgcaaaac aagctatatg gaaaaagttt
     4321 aaactttttc tagagtccct attactagtt aaaaagacca ctgtagtcct ctgataaatc
     4381 atcataaaga ccacagtagt ccccttaaag tttttccaaa ttaactatct gagaaaggag
     4441 agaagatttt tgaatcaaga aatagctgat attaaattaa tcaaagaagt tttacaagaa
     4501 tctaccgcaa acgcgatagc atctggatca gggattagct taagtacagc aaaaaaacta
     4561 aaaagtggcg agagaaatgt agaaaaacta aatctttctg atgcaataaa aatcactgag
     4621 tttgctatta agaataggca tgtgaaaatt gaaatttgga aatgacggat acaactatta
     4681 tagttttgtt ttttctaagt atcatattta tgaatatgct tttgctaaac atctaattat
     4741 agattaattt ttatccaata tctataattt tccaattttt taccttttgg agagtaaggg
     4801 taaattcaaa gatattgctt actttagttg tattattaag atacttaaca aaaatttctc
     4861 cttgaatttc ttttcctttc agtttaaaag taggattaac caattcaact aatttcaaat
     4921 tactattaat tggctgaact gctttgtttt caacatagta ttcaagttcc ttttccgatg
     4981 ctgatggata cagtttaaaa aaggtctcta aaaaatcggt gacttcttcc gtggttttag
     5041 catcaatgtc agattcgatt cctatttgtt ttgattcata ttttgccttt tctggctttg
     5101 caatcatagt aggcaaactc gttactatat ggctcccatt ttcatcttca aagattgtca
     5161 ctcgatatgc agaagaaatt gattgtgtct tttttccctc tgtaatctgt tgctcgacta
     5221 aaaatgaaac gataaattct tccgagtgtt tttcaacatc tagaattttt atagattgaa
     5281 cttcggaact cgtgggaata tctgctcgaa ccatatcttg gcttaaagcg agaccgtttt
     5341 ctgtaaggta ctgttcgaga ttactcattc tcttttcaat tgcttccttg ttatttctcc
     5401 atgaaaaata ttctttcgca aaatcctctg taaaactttc aacgcctgaa gtattcacta
     5461 ccttctcttt tataactact ttttcatgag tcgtatgctg atcaatggct gtgaaatttc
     5521 tgtagattcc aaaagcaagg ctacaagaca ataaaagcca aagagcaagc accatttttc
     5581 gatgcttgcc cactgaaatg actcgttctt tattcttttt tgggctcttt tccttttgat
     5641 tccgttcaat ttttatcttc atgttttttc ctcttttctc ttatttgtac cgtccagcac
     5701 cgataagatg ctgctgccaa tagctttctg ttagatttgt ccagcccact ggatctcctg
     5761 catgaaacat gcgattctct cctgcataaa taccgacatg ggtcacataa gtaccggtat
     5821 cataagtcga atgaaagaaa accaaatcac ctggtttggc atcttttaca tcaatatggg
     5881 tcatggcatt atactgatct tgagccaccc gaggaagttt cagaccaact ttggcataac
     5941 accattgagt caagccacta caatcaaacc cagtttcggg acttgctcca ccaaacacat
     6001 aagccgttcc ttcatactta aacgcctcat caaaaatccc ttggactgtt ttatcatcaa
     6061 actgtgttgt agttaggtat tgcttcacta ataagcaata aaacatattg ccatagttat
     6121 accgccaccc accatttttc ttaatcgcta tgggattagg gtaatcaact ttttggccgc
     6181 tcgatttttc ctttgaaaaa gattcggcta aagcaaaatt atgcttcttc ccgtttttcg
     6241 cgacatgatc cagatacccg ccaccatagt tatacgcttg aataatgcta tcttgatcac
     6301 accctagttc tttggaacgc ttaaccaaag acgcaaaata gagacatcct tgtttgatgg
     6361 atgcctcggt acttaatgaa ttcggtggca acccggctga ctccgaactc tgcatcacat
     6421 cttccattgt gccaccagat tccacttgaa taatcgccaa aagaatcagg acatattctg
     6481 agatgtttga ttccttggca tatttttcca ccattgctcg gtgtttcaaa acttcttctg
     6541 agacattact tcccccagaa gaagcacctg aactattact tccttcactg tcttccccaa
     6601 acaacaagcc cacacacatc aagacgacca taaaggagag tgtcaagatg gttaacgaaa
     6661 tgatacttaa tttctttaca ttcatttttt ctcacccgac cttgattttg gacgagggtt
     6721 cattcttttt tgtacttttt gattggttcg cttgggcaga gtagacctct gtttcacttg
     6781 ttggaaagaa tttttcttac ttgatggttg acttattctt tttgaaacaa tttcatgact
     6841 agatagtttt cgtttgattt cgggattcgg atttactctc acaatctgtt ttggtgcttc
     6901 tttttttggc gctctatctt tttgaggttg gcgctctggt tttatcgaaa cattttccct
     6961 tcttttctta tgacgattac cggtttcgtt caatactttg cgcttttcag ccattttttc
     7021 atctctatgt tgtcgttgtt tttctctcaa ctccgctcga tttgcttttt cttggacaag
     7081 tccgcgcttg aattctttcg gtgctttttt cgtcttttca attcctttgt ggaagttgta
     7141 tttcaagttg gtcggcgtat tccttacctg atcccttact tgtttagtct tatctttcac
     7201 caaagcttgg gtatccagaa ctttgcccat ttttctccca gccaaattca ttcgggattg
     7261 tttcttatta tttgaaactg gattctcctt agtcgagtca gatggtacct cgtgatcgtt
     7321 aggtaatcgt gaattctttc gtagagaaga accggatggc ttaaatttgg attttgattg
     7381 ttccttttcc aacttatgtc caactgctgc accaccgcca aaagccagag ttcggatcac
     7441 atttcgattg agttgccgca atttacggtt catcaacatg tgcggtttcc gcatgatgcg
     7501 ccttcccatt gactgactat cattgctttg gagattgaac atactcatga tgtcacctaa
     7561 tttgaaatag ataccggcaa aggtcacgat ttgcaggaac gcaaccataa agaaaggata
     7621 ggtagctgaa atattgaaaa acatggtgga gatactaaaa gcagtcgtaa tgactaaggt
     7681 aactcccgct cgcatcataa tcgtattgaa taaacgaata atcgccttct ttcccaagct
     7741 ctcataagtt ggtaacatgg ataacagaaa actaattggc agaaacatgg cgaaaatgat
     7801 aaagagaatt tgggagaaca acataatccc cgtcagtaag aagacaaaga atgagatacc
     7861 aatattaaac aacaccaaaa agaccacggt ccctagtcgg ttcatggtct ttgtaatact
     7921 tagattcgcg ttgtcattgt cttcaatttc agcttttacc gcttcttctc gatcctttcc
     7981 cttattttca tctggactca cagataaaat tttattgacc cggtcttcac caatttcttc
     8041 tatgttggaa tcatcaaatt gcaacaagag ccaaggttgt cggacttgaa tagaaaacaa
     8101 actatcacga atcaaatcca cactgtcttt tcctttgctt tccgaattcg gcacaacgag
     8161 ctctgttccg agactaagag ccgcttcact aacatccgaa ctaaagttat tgatttttgt
     8221 gatataggta ggcgcatacg cgataaagga accagagaga aggaagatcg ttacaaagtt
     8281 aatgacagcc cggactgctt tggtagcttc tcgctttaat agtccgatat acgccacata
     8341 gactcctaga gctaaaatca ttaataatag aaatccaaaa tagaaacccg agacctgtaa
     8401 tccattttca gtaataccgg ctagcgtttg gatatttttc ccaatacttt ctgccgtatc
     8461 cgaaataaaa tctaatttgt acgcttcttg taccacatac ccggtcgcat ttgataaata
     8521 caaactaacg gtccaaatga aatttgtaat ggcgtagaga ccgtacatca cactctttcc
     8581 taacccatcg ccccagttcc aaggcagcca gccccacgaa ctatctacaa agaaatccaa
     8641 ttgatagtta tcaagtgaat attgagaata gagattgcca gatttaacgg tatcatcaac
     8701 taatccagtt gcttccgcta ctgttccaat cagactcaaa agaagtaaaa tggtgcagag
     8761 actaattgca attattccca caatccgtaa aagtttcttt ttcatctcct cactccattc
     8821 tcttttgaac aggcgggcgt gtatcaaaag catggaagag ttcttcaaag actggatgca
     8881 cttgtaccac accaacgcga ccatacaagt cctgcatcaa acattgccca ttttccaaat
     8941 ctcgcagacg cttttgattg ctttcatctt cttgatcaag accaaagaat tcgagtgtct
     9001 tcttgatttc atgaatatct gtgcttcgaa aggcaaattt cagcccaatg ttgtttttca
     9061 gacgttcatc taataaatca tcactatttt gagtgacaaa gtaaacgccg gcattcatag
     9121 cacggccagc acgaactagt ttattcgaaa gagtttttcc ttgtgcgact tgaaggaagc
     9181 tccaggcttc atccaaatcc acgattttga aaatttctcg attgctatga ataaaatcca
     9241 aggcaaatgt ggagataaca atcaacatgg aaacactaag caattccatc gtagtgtact
     9301 cttcaaatgt agtctccgca tccggcaaaa ccaaatctgc cacctgaatg atattcaatt
     9361 gtttctctaa actaatcgat tgtgtaattg aaccatctga aaaaagtaaa tgcgcaaaat
     9421 cataatcggt aaacgattca atatgatcag caatattttc cgcaactggt gtcccatcat
     9481 ttcgaagctc ggtaatgact tgtaacaacc cacgttgatt gctttgggta acggttcgaa
     9541 tagcttttcg taaaacggga aatttctctc catcccgact agaaattcca gttagaaaag
     9601 tcagaatatc aattgctaga ctttcagaat ccttcttttt cttcatgatc acatagggat
     9661 caagtaaccc ttgattttct ggtttactgg ttaggttgag gatattaatt tcactcgcaa
     9721 tttctggtaa ggtttctttc cagctaccac gctctccttt gggatcaaca atcaccgctt
     9781 gaccgccaaa caggacagca tagtaaacta aaagattatt actaaaggat ttcccaccac
     9841 caagtgaacc aagaaaagcg gcggccagtg cattggtgac ggaacctttg accccttgtg
     9901 aagccaatgc cggtttaaga taaacattgc gtccagtatc cacattgtag ccaaaataaa
     9961 ttccctccaa ttctcctaac atttgggttg ccccaaagcc aagcccagca agaaaatcag
    10021 aagtaaatag cgataggtaa ccctttgaag ttatctctag gttttccccc gctccacacc
    10081 gtacgtgcaa ctttcatcgc atacggcgtt ccaacttgtt cgtatttctt tagtgaaatt
    10141 cagttaaatt acattctaaa cgatatttgt ttaacttctt catttgctta tttgttagtt
    10201 gaagaagttg tagatactct ttaatcgttt cttttgtttt ggcatggatg agtctgtgta
    10261 cccatttatg gataataact aggttatcaa actcatctgt acccccaaat ttacgaggaa
    10321 taatatgatg acaatgaaca tcttgcgttc ttagaaaaat ccctgtaacg gaacattttc
    10381 cattttgcat agaatatctt gacagtcgat tgtctaagta ttcaagactt tcatctgttt
    10441 ccatcgtact aagggtaacc aattcagaat aaaccgaagg ttttaatttc ctcagtttag
    10501 ccaatcgtcc atcttgcgta tagttgttga tgtgaggttt gaaaaattct aaccttttcc
    10561 atttcacgct atctaatgga aataaataat tcttcctaac acaaaacgtt ctttttgtga
    10621 gaggataaaa ctttttatac gtaatgggtg ggcttctagg gatttcatat tttccgaatg
    10681 gttttaaacg attatatagt gctggtaagc aggaatagta gatagaagaa aagtcatggt
    10741 taatcaaggt ggctttttga taataattct gaatacctcg tacatactgg ttgtattggt
    10801 taacagtttt tctagtagga gatttctgaa ttgcttttat cttttctctg atttccttct
    10861 taattctact ttttgatttc tttgagactc tcgaaacagt aacatattgt tgtttctttt
    10921 gttttatgac ctttagctcg aatcctagaa attctgaata atttcttcta agatttgtaa
    10981 tttttgattt gtctggtgaa atatctaggt tcaaccgttg tttaatatat cccttgaccg
    11041 catgatagat ttttactgca tgtttatgat ttgttgtaaa gattttaaaa tcatcacaat
    11101 aacgtacgat gtgcattttc tttaatttcg actttaccaa agcatggtgc atattatcta
    11161 cactgctata ttttcttttt gtttgaaatg tttcccattg attggcaatc caccaatcta
    11221 agtcatttag aacaacattc gataataatg tagataacac gccaccttgt gggacgccag
    11281 aagtggaagt gccttgtcct gctactgtca cttttaacat tttagagatt attgctaata
    11341 cgcgtcgatc ttttataccg atggtataaa gctgtttgat taactttcca tgatggacgt
    11401 tatcaaagaa tcccttaatg tcgacatcta ccacatgatg acatttgcat ttatgtgcaa
    11461 taaaattaca tcttgctatt gcatgttctg tagagcgatt aggtcggaac ccataggaat
    11521 gtttgaaaaa ttttgcttca catatgggtt ctaacacttg tttaaacatt tgttgtatca
    11581 agcggtcttt catagtggga atgcctagag gacgagtttt cccattactt tttggaatgt
    11641 tgactcgtct aactggctgc ggctgataat tttcaattgt ttttcgaata tcatttacaa
    11701 acttttgttt gttttgaaat ttgaaatcac tgattgtttg attatctatc ccagatgttt
    11761 tagaaccagt atttgattta ataattctat atgctagtag gatattttcc tctgacataa
    11821 ttattttata aaggtcaata ccttttgttg cttgtttgct acttctttca tagagccaat
    11881 caaaagtttc ttgcatttga tagtattcat aatatcgtaa ttctgtactc actgatggat
    11941 tatttctcct aactttaaaa ttagtcccat cctcttacca gatcttgtga gtttcattta
    12001 actgtattca cttttcaaag aacaagtctt ggggctatcc ctccacgttg attagacgct
    12061 tcacaggtac tgtgccccta ctctcgcaga aattaaggat tttcgactat tagtcttata
    12121 tccaacgctc caataacagt tgttgaataa gtgttttctg ttttcctcgt tccagttatt
    12181 ctagccatac atctatcctt aggtgcttac tttgagcctg aatattatat aaggtcattg
    12241 ttccttatcc cgaatttcat aaatacgact cttacttttc ggtaatattc gttgcttttg
    12301 caacccaatt atctttcgat aaaagtcatc ctttagaccc gtacattcgc aagttcgtca
    12361 gttccgtagg aacattctca ccatagatag tttgtggcgt cccggcatat cctttaccat
    12421 ataagttatt acttacttag gtattgttct gccgacttta cctagcttca cacgaatatt
    12481 cactgttatg aatattcgca tgtaggagta tcagaccagt tgcttcaacc aacttgacgg
    12541 ttttcatttc aactgtgaaa taactagttg taattatctt tagttcttga taattctccc
    12601 atttcatgcc tatgcactta tagggaaacg agtcgcacca tattggatat agtcattcat
    12661 gtatcgcttg ctagctggca aaaactcttc atgaagtccc atcatatcgc caaagggacg
    12721 aaccaatttt acattggtat catcataaaa atctaaaacc tcatcacacc gacgttttaa
    12781 ttcatccaat gattctgcac tcactcgaac aacatagctt aatttgtaca tggattcttt
    12841 ggattgatcc aacgttgttt ctagttcatc cacggagtcc aacgcatcca agacattgga
    12901 attggtttca ttgtcggact ggtacgcatg gttgtctaag tctttcagtt cttttttctt
    12961 attgcgaact gtcgccagtg cctttttatt cgtcacgatt tctacattca tactcgtgtc
    13021 gattgggaaa gtgaattgtt gttgctggta ataaaagagt tcagaagatg gaaactccat
    13081 ctcaccgaca atcgtattaa tcgttagata ggccacataa gattcatgat tttcatgttc
    13141 catgtgtaag taccgaggct tctcttcaat caaacagcga cttgggcgaa gtaggtcata
    13201 gcgctttatc aatgtttcag attttagctt tttcttagac aactgaaatt catattcttc
    13261 aaatggtgtt cctttttctc cataaatgtg ttcaatcaaa taagttagat cactaggtgt
    13321 tactcgtctt actttgaatc tacgagccaa tttactttcc atcaattttt caagcttagt
    13381 ataccggcga atttcttcat tggataacga aacaaaatca cccatcaaat gatgattcac
    13441 tccatagaca aactcttgaa gtccggataa aaaagagttc ttgagacttt tcaggtttac
    13501 ttcttcgtct gtgacaatca gtttgaagcc aataaaaaag cgatagtcaa tttgactatc
    13561 gccaatcatc gataccaatg catccgtctg taagtcgatt ctctgttttg cgacttcttt
    13621 caaacgacca gttatctctt ttttcgaccg ttcctgcgtg gcacgaatgc tgctttctgt
    13681 cgcaatttgt aacgcatgaa tcttaccttc acgattttgc gcaatcaatt ggcgaaagtt
    13741 atcgtggact tgatacttct gttcaagtga taagaaggag taattgtaag ggactagttc
    13801 gtagtaagca aagcactctc cctcttggtt aaaaacaaga ttattttcaa tatatttaat
    13861 cgggtacata attcacactc ctcactaggg tgattggttc atcccatcgt tttttctgtt
    13921 ctttgacttt ctttcctgca aaagtaacct taaatcgcaa gtgataacta ataaaggatc
    13981 gtaaaaaccc taatggcttc tttccatcaa aggtcttttg cgacataaac caagtgactg
    14041 ccacaggtat gcccaagtat tttaaaaatg ccccctctat catagatagt ggaggcatat
    14101 gagcaaacac aatgacaaac agcaaggata agacaaacca agccatttga ttaaaggtta
    14161 caggaaaagg cagctgaaag tcattgattg cgtaaatgac tttttcaact gcccagatac
    14221 tggtatagct ttttattttt ttcattagtt tcacttccta aaaaagcgcc tgataaagac
    14281 gactctgcat gaatattaat tttcttttta aaagtgtatt ccaactttca atctatcaac
    14341 tgaggtttat cagaccataa tctgtggatt tcttggtatc cagctgaagt aataaaagta
    14401 tatctttgtt gatatattct atcttgaaaa tcactaaacc gtatttttat ttcccattta
    14461 ctcactgaat atttagggat actcattact tcgttattat atttcatcca atataattca
    14521 aattctgttt ttttccctac tcttagaata tctgtatcaa taggcgctga aactcctaac
    14581 gcatccagac tatcatcaat atgtttttga gccgaaagta atgataatag atttacttca
    14641 tggtcgtttg tgttgatagt ttcttctaaa tacacaaagt caattgaaaa agccattccc
    14701 agaccttcat taataagctc aaatggtaat ttaaaaacat cattttcgtc agactttacc
    14761 attttaccag caaaacggtg ttcagatatt ttgggtataa gttttaaata agggtaataa
    14821 cttagacggt cctgctcttc atttctttgt ttttcatcag catattgttg ctttgataaa
    14881 tcaagtgatt cctcatgttg tctctcttgc tgtttcatcg cttttttatg ttgtttattt
    14941 gtaaaaaaaa gtgtgataaa acatactgca aatgaagtta gtacagggac aaatatgtct
    15001 ataaatgatt taaggtcaaa gtcaaaattc ataataatca taacctccag cattatatat
    15061 ttatcaataa ttatatccct aaacctatat catgaaaatg tttatcctat gaattcaaat
    15121 gttcctctat ttgtcacaag ataatttcct tctagttcca agtcacgtcc atatgcttca
    15181 tagtcaatat agttttgcaa gtgtgtaggc acctctccaa aagcacctgt ttcttcaatc
    15241 aaataatacg ccacatcact catatcgtta caatcgggat aacagataat atcatccaca
    15301 tgctccacca tttcctcaaa agagttgaag aaagcatgtt ggatttccaa agcaacttca
    15361 ccaatcggtg ttccttctag ttcctctgct aaaccacaca accgattgat ttcctcaatt
    15421 ggtgtatatt catcaatctc aaaaggcaac tcataatcat ggatcgcata ctcttcgtat
    15481 tcgtcattta aaccaatccg ttctttcact tcgtcaaaat cgacaggtgg gctaaaccaa
    15541 gcccccacca attcaccttc gttatatttt ccaaggttcg caatatatac acgcatctgc
    15601 tccataatgg tcccccttac gcaccgacaa tccgattaaa caagttgagt aagacatctt
    15661 tcacaccaga agcgttgaag accagtccta ccgcaatcag cgcaatcacc aaaaaaccaa
    15721 tcagcttgga aaactcacgt ttgaagccta aaaataaacc aatgaccaca attgccaata
    15781 agactaaaga ttg
//
LOCUS       DAFEKH010000063        15313 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.066, whole genome shotgun sequence.
ACCESSION   DAFEKH010000063
VERSION     DAFEKH010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15313
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.066"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            278..787
                     /locus_tag="LP386_002347"
     CDS             278..787
                     /locus_tag="LP386_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL1919557.1"
                     /translation="MVQGIERGVYVVDKIQFNQVIEEFIKVNNLMTHIQKRPIRITND
                     LKLSTSMIHLIDVIGNYPETSITELADRLGVTKGAVSQQIPTLEKMNLISISQKKGNK
                     KTKLVSLTKYGRKVYESHNYLHEELYSSINEALESFSPDQISTIKQILEKVSYTINEY
                     QVSLTRKED"
     gene            880..2042
                     /locus_tag="LP386_002348"
     CDS             join(880..1156,1156..2042)
                     /locus_tag="LP386_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBL1919558.1"
                     /translation="MSRRQRRTYSKEFKQQVVDLYLAGKPRAEIIRDYELTTSAFDKW
                     VKQAQTTGSFQEKDNLTPEQVELIALRKKNKQLEMENDILKQAALILGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
     gene            2322..3302
                     /locus_tag="LP386_002349"
     CDS             2322..3302
                     /locus_tag="LP386_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1919559.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLPVKLIKKNTA"
     gene            3424..4842
                     /locus_tag="LP386_002350"
     CDS             3424..4842
                     /locus_tag="LP386_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HBL1919560.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            4913..6382
                     /locus_tag="LP386_002351"
     CDS             4913..6382
                     /locus_tag="LP386_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL1919561.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            6392..6859
                     /locus_tag="LP386_002352"
     CDS             6392..6859
                     /locus_tag="LP386_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL1919562.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            6895..7767
                     /locus_tag="LP386_002353"
     CDS             6895..7767
                     /locus_tag="LP386_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL1919563.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFITSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            7849..10383
                     /locus_tag="LP386_002354"
     CDS             7849..10383
                     /locus_tag="LP386_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL1919564.1"
                     /translation="MKKKMKDEVLEYIKNNLKYYDFSAQDIAMKFCIKRNVASHYLNQ
                     LFSDGKLLKNDSVRPVMFKYNQQKPKDCFSKFIGADISLKSTIDKCKATVMYPPNGLP
                     LIIKGNSGVGKSFLASLIYQYALDRKVIHNDAKFVVVNCADYANNPELLSAVLFGYKK
                     GAFTGAEKDTAGMLSSANGGYLFLDEVHNLSAENQEKLFLLMDSQKYRKLGESVQWEY
                     ANVRLILATTEDKNTSLLATFRRRIPAEITLPDYNNRSTSEKIQLLFEFLKDEAITID
                     SKIFCSIELFTDLLSKTFEGNVGELRNEIKLLCAEGYLGNKRKSSIYLGDKLDSGFWI
                     DPEISIDLKKMFLKSLSEIDLIELFQNHISIEESMSQLRDRILKECAGSSEYNYLESD
                     EFIALRNYVVNKISPIIDSTGLCLLDEFLADISLFIMFIDVIEETSRNFLLSKFRKFR
                     MKNDKQKLLANEIWSSLEVEESKQELLLKWILFLVKKFYVKIPETHCLIVMHGKITAS
                     AIARETNKLLNTYVYEAFDMPIEGETSDLINLINNFCKSIDTTNGLILLVDMGSLEQM
                     YEKIESNVIGDLVILNNVSTALAIECGIQVCQKKPISHFYQMDFDSFQVKVQYYKGLS
                     QKKNVIVSCLSGEGISEKVKDILKRYLDNQVEILIFDFNALKKIAKEKDTMIFKNTIC
                     VLSTTEFYIQGIDCLNLENLINGNQTLEKLNKYMDSDSCEFCLNELVKLFTIEGASTK
                     LRFLDSKKVFNEIEKVLYLYEKYYDVKIPSFLRINLFLHLSGMIERIMIGDGITNEHL
                     KEGAQLFDTFLNVSKDFFSEIKDIYCIEIPKGEYELIYTIFEQTIF"
     gene            10539..11312
                     /locus_tag="LP386_002355"
     CDS             10539..11312
                     /locus_tag="LP386_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL1919565.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
     gene            11305..12096
                     /locus_tag="LP386_002356"
     CDS             11305..12096
                     /locus_tag="LP386_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL1919566.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            12106..12597
                     /locus_tag="LP386_002357"
     CDS             12106..12597
                     /locus_tag="LP386_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1919567.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            12615..13025
                     /locus_tag="LP386_002358"
     CDS             12615..13025
                     /locus_tag="LP386_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL1919568.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            13029..14429
                     /locus_tag="LP386_002359"
     CDS             13029..14429
                     /locus_tag="LP386_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HBL1919569.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIENFKEITPFSSFKLEKEFGKKERVIVP
                     KIEDYFLFETTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPNYPWPQ
                     MFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMTVTEGA
                     IKVDKLDYSINYECGF"
     gene            14452..14826
                     /locus_tag="LP386_002360"
     CDS             14452..14826
                     /locus_tag="LP386_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL1919570.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYESLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
BASE COUNT         5315 a         2156 c         3060 g         4782 t
ORIGIN      
        1 ttttttattt gtctcgctta attatacaaa cggcgtgata aaaaacgaga aatgaattat
       61 aggtttagac ctttatcatt tctcgtttta ttttattgta tcaaggctct atcataagtg
      121 gtaaaatcta cttttaaatc acatgtaatc attgataagt ccagtgtttt agcggataat
      181 cagcttttta tttatttttt cttataaatt tgataaatag aaattagtat agccctaaac
      241 aaattatttg tgttttattg tttagggcta tactatattg gtacaaggaa tagaaagagg
      301 tgtttatgtg gttgataaaa ttcagtttaa tcaagttata gaagaattca tcaaagtaaa
      361 taatttaatg acccatattc aaaaacgacc aatcagaata actaatgatc taaaactcag
      421 tacgagtatg attcatttga ttgatgtgat tggaaattat cctgaaacta gtattacgga
      481 attagctgat cgattaggcg ttaccaaagg agctgtatcc caacagattc ccactttaga
      541 gaaaatgaat cttataagca tttctcaaaa aaaaggaaat aagaaaacta aacttgtatc
      601 gttaacaaaa tatggtcgaa aggtgtacga atcacataat tatttacatg aagagcttta
      661 tagctcaata aatgaagcgt tagaatcatt ctcaccagac caaatttcaa ccattaaaca
      721 gattctagaa aaagtatctt atacaatcaa tgaatatcaa gtaagtctga caagaaagga
      781 agattgacat gaaaaaaatg atttttgaat cggctacact agactagaca gaaaaaataa
      841 ggtgtgtaaa ataaatgaaa acacactgga ggaattttta tgtcaagacg tcaacgtaga
      901 acctattcaa aagaattcaa acaacaagtc gtcgatcttt atctcgcagg aaagccccga
      961 gctgaaatca ttcgagatta tgagctgact acctcggcct ttgataagtg ggtcaagcaa
     1021 gcgcaaacta ctggctcgtt tcaggaaaaa gataacttga cccctgaaca agtagaacta
     1081 attgcattac gaaagaaaaa taaacagctt gaaatggaga atgacatttt aaagcaagcg
     1141 gcgctgatat tgggacgaaa agacaagtaa ttgataccaa taagcacaaa tactcaatat
     1201 cagcgatgtg taaagtgtta aacatctctt gccaaaccta ttattatcaa gccaaaccag
     1261 ttgaagatga atcagaactg gaagaactcg ttcaagaaga atttattcgc aatcgaaaag
     1321 cttatggtac caggaagctg aagcagtgct tggccaatct aggtcttcaa gtgagtcaac
     1381 gcagaatcgg ccgtatgatg aaacagcgtg gcttgcgttc aacatacaca ttggctcatt
     1441 tcaaattcca ttcttctact tgtaacgaag ccaagaccgc caatattcta gacggaacct
     1501 tcctacagga aaagtcatta gaagcgattg taaccgacct tacctatgtt cgtgttggga
     1561 agaaatggca gtatatctgc ctgattcttg atttgtttaa tcgagaaatc atcggctatt
     1621 catgcgggga gaagaaagat gcgacgttag tcaaggaagc ttttgcaaag attccgtact
     1681 cgttgaataa tgtacaactt tttcacacgg atcgtggaaa agaattcgat aaccagacga
     1741 ttgacgaaat tttatgggcc tttaatatca cgcgttcctt aagcaaaaaa ggctgcccct
     1801 atgataacgc cgttgcagaa tccacctata aatctgtcaa agtagaattc gttcatcaat
     1861 accgctttga gacattggct aatttgcgat tagagctatt tgattacgtc cattggtgga
     1921 ataccatccg gctgcacggc acgttaggct atgagacacc gatcagtttt cgacagcaga
     1981 gattggcgca gcgaatcctt gataatgagc tcggatgtga taccggtggc gaggcacctt
     2041 aattatttga atgagcttct gccttagaga atcagattcg aggaggctcg ttgtcaaggg
     2101 cagtcggaac accagcagca agcttacgca ataccttata atttttgtca aaaaaagtgt
     2161 tgccattcca catatatctt taaacagcta ttgccagata aaaataaatg atattatata
     2221 tataaatact tatccgaaaa ggggaatgag agagtcaagg ttcttggaat gtcgaatagt
     2281 cgagtaggta gattttctat ctacaacctt gttgtttaaa aatgaaaaaa attggaatta
     2341 gagaagttgc gaaagaggca aatgtttctc ctacgactgt gtcgagggta ttgaatgatc
     2401 gtggatattt gagtgaggaa acaaaaagaa aagtttttga tgccatgaaa aaattagaat
     2461 actatcctaa tgaactggcg agagcacttt ttaaaaacga aacatatacc gtaggtttga
     2521 tttttcctac aattactaat ccatttcacg ctgagttaat tcaagatatc gagttcgagc
     2581 tttccagcag gggatataaa gtgttgctgt gcaatagctt aaacaatcca acaaaagaaa
     2641 aagagtactt gacgatgttg agaaagaatc aggttgatgg aattatagta ggaacgcaca
     2701 ataaagatat tgcggattat gatattccag ggctacctat tgtagcgatt gatagaagtc
     2761 ttggtgaaaa tacagttaca gtatcttgtg ataattacag gggtggggaa ttagctactc
     2821 aactacttgt aaatcatggc tgtcagaata tactgtgtat tcggggagat agtaagataa
     2881 agctacccgc gaatagtagg actttagcat ataaagatgt tttgaataaa ttcatgctgg
     2941 aaccgttagt cctagaagta ccatttgtaa aagaaatcaa tgaaaaaaat gaaataatta
     3001 agacatatct ggaaactcat ccaaatattg acggggtttt tgcaggagat gatttattgg
     3061 cttctttggc gattaacaac ttaggaagtt cgggcaaaag agttccaaaa gaggttaaag
     3121 tgattggatt tgatggagct caacaaacat tgatttataa tccagaatta tcaactattc
     3181 aacagcctat agatcaaata tctaaagtag cagtaaaaaa attattgaat atgattaagg
     3241 gcgaaaagga gacggatgaa ctttcacttc cagtaaagct cataaaaaaa aatacagcat
     3301 aagttaaatc ggcgaaaaat tccttcgtcg atttaaaaat atttttatga aacgggttga
     3361 catatgaaac gggttgacat atattagttg tgaagataaa aaccttttca ctggaggaag
     3421 aaaatggaga aattattaat taaaagcaat aatcatcaac tttactacca acctaaggat
     3481 gtttgggtcg gagatgttat gccttacggg aaagaaggaa aattctttat ttatcatcaa
     3541 cgtgatacta gaaatccagt tccttttgga gaaccgtttg gctgggcttt agcaactacg
     3601 aaagattttg ttcattttga agactttggg gaatctcttt taagagggga tgacaatgag
     3661 agagaccagt ttatctacgc tggttctgta tttgaggcaa atggaaaggt tcacgcattt
     3721 tatacagggt ataatcgtga attcttagcg cagggaaaga catctcaagt gttgcttcat
     3781 gctgagagtg atgattttgt tcattgggaa aaatcagaaa cagcattgga gttagaacca
     3841 caagaagggt atgatattcg aaactggaga gatccatttg tcgtttggga tgatgaaaaa
     3901 gaagaatatt tgctaatttt aggggcgcga aagggtcagg ataaacatct acaaaccgga
     3961 cgtttagtgg aatttacatc aaaagattta actaattggg aattcaaagg tgatttttgg
     4021 gctccgggat tgtataccat gtttgaaatg ccagaacttt tcaagattgg tgactggtgg
     4081 tatcttgtct attcagaata ctcagatgga aataaaatac tctatcgaat gagtcaaagt
     4141 ttggaaggtc cttggattaa gcctaaagat gaagcttttg atggacgggc ttattatgca
     4201 ggtagaacag cttatgatgg aaaacgtcga gtcctatttg gatgggtacc aacaaaagat
     4261 caagaaaatg ataaaaacaa ttatttatgg ggaggtactt tggttcctca tgaagtctat
     4321 caaaaagagg atttttcact tggggtaaaa cccatagacg aagtgtggaa tgcattcata
     4381 aatttacatg atattgccga tgtagagata gaaacagcag acacaagaga agaagtaacg
     4441 cttgtcaaaa atagtggaac tttgtttaat ttagaaacaa caatttcatt tgatgagaat
     4501 cttagtgact tttcactgag attatataaa aaccttgaga cagatgaatc ttacgaatat
     4561 cgcttcaatt tagatgaggg gcgtcttaca tttgataaaa acccttgtta cccttggttt
     4621 caatatatgg ataaaggact tattagacct atatctttaa agcctaacca atcttataaa
     4681 ctaaaagtga ttgttgatga caatataatg acactttata ttgatggaat cgctcttaac
     4741 gctcgtgtac atggttgttt tggtcaagca attactatta cagcaacaaa tggatcaatg
     4801 actgcaataa ataccaagtt ttcaaatgaa ataaagaaat aataaacgtc aatcatgtgg
     4861 caggtctgaa aatcaaacat gacctgtcac atttaaaagg gaggataaat gaatggacta
     4921 caaaaaaatt gccgaagatg tattggaaaa cgttggagga aaagagaata tctcaagcgc
     4981 tacacactgc attactcgtt tacgtttaat tcttaaagac aaaagcaaag cgaatatgga
     5041 aatgcttgag gaaatagaag gtgcaaaagg tgttcttttc aatagtggac agttacaagt
     5101 aattttcgga acaggtataa ttgaaaaggt ttacaaagag ttcgttgaat tgacaggagc
     5161 taaggaagta tccgtttctg aaatgaaaga cgaaggagtc aataattcag gaaatagact
     5221 tcaacgagct tttaaagttt tctcggatat ctttattccg atcattccag cttttattgg
     5281 ggcagcaatg gttttaggaa ttcgttcgtt gattaccact cctggaatgt ttggaatgga
     5341 tggctcattc gctgatcaca atgtattcct aaatgattta tccaaatttc tgggtattat
     5401 tgcaaccaca tttgattatt taccagtttt agttatgtat tctgcaacaa aacgttttgg
     5461 cggaaaccct attttaggat tacttgtagg atttgttatg attcatccag gactagccaa
     5521 tcggaatgat ttcgtcatgg gaactataaa gcctgattat tggcatttat ttggattaag
     5581 cattccagca gttgcgtttc aagggggtgt ttttccagca attttgactt cttggttttt
     5641 agcaaaagtt gagaaaatta caaataaata ttctcctcaa gtacttgctt acattttagt
     5701 cccaactgtg acaattgttc ttgccaactt tgcactattt ttagtgtttg gtccattggg
     5761 gaattttatc ggtaatgttt taggtggaat cattgatttc ctatatatga agatgggtgc
     5821 ctttggtgct tttgtttttg caggcgcgtt acaaccatta gttgtaacag gaacacaaca
     5881 tgctattcaa ggtattgagg caaacttagt cgcaacaact ggattcaatt atatccaacc
     5941 tatttggtca gtttcaatta ttgcccaagg tggcggttgt attggtatgt atttactctt
     6001 taagaaaaaa tctaaagata gagatattgc gatttcaagc tttattccaa cactggtagg
     6061 tattactgaa ccggctatct ttgctgttaa tttgaaatat tcaatcgttc cttttgtttg
     6121 ctcgtttatt ggtgctggtt ttggtggagc atttatgaaa atttttgatg taaaagccat
     6181 tggacaagga ttgactgtat tgccaggtct gactattgct aatccagttc ttccttatat
     6241 atttggtaat ctcatagcat tcattttacc aatcattttt attctcgctt atgataaata
     6301 taaagtgttt atccctgaag ctaaacaccg taaatttgca gaaaaaactg actcaaaaaa
     6361 attgccagtt caagtaaagt gagatgagag catgttaaat ttttttagaa aaaatgaaat
     6421 aagcgttgta gcacctgcaa ccggtgtttt tgaaaaactg gagaaattaa gtgatccagt
     6481 cttttcaaaa ggaatgatgg gacaaggatt tgcaattgat gcaaaaaacg aaacgattgt
     6541 atctccaatc gatggttttg tttcaagtat ttttcctaca aaacatgcct taggaataaa
     6601 aacaaaatca ggaattgaga tacttgttca tgtaggaata gatacagttg agctaaatgg
     6661 tgagggattt gatattaaag ttcaagaagg acaaaaagtt aaggctgggg atattcttat
     6721 gaccattaat tttgtagttt ttgaaaagaa tcacaagact aaagatgtca ttgttgtttt
     6781 tccagactac caagacgaaa ttttcattcc gaaacttgaa gaagtaaaac aaggacaaga
     6841 attgtttgtt cttggctaat gataagtaat taataataga atcgaggaaa atgtatggtt
     6901 tttggggcta ttgaagctgg tggaacaaaa tttgtttgtg ccattggaga taaagatttg
     6961 aacatatttg aaaaagtcag ctttcccacg actacaccca aagaaacaat gaatttagtt
     7021 ttagattttt ttaatcatca taaagatgat ttagaaggta tcggagtggg atcgttcggt
     7081 cctattgata ttcattgtga atctaaaacg tatggcttca ttacatcaac gccaaaactt
     7141 gcttggcagg attttgattt tattggaagt ttaaaaaagc aacttaatat tccaactgct
     7201 tggacgactg atgtaaatgc ctcttgctat ggtgaatatg tttctggaaa tggcagaggc
     7261 ctttcaagtg ttgtttacta taccgtagga acgggcatag gaggtggcgc tatccaaaac
     7321 ggaaacttca ttgaaggttt tagtcatcca gaaatgggac atatgcttgt aaaacgacac
     7381 aataaagaca acttttctgg gacatgtcca ttccacggag actgtttaga gggcttagct
     7441 gctggtccgg caatcgaaag aagatcaggg aaaaagggac aagaagtgac tgaaaatgac
     7501 gttacttggg aaatagaagc ttattacatt gctcagtgtg catataatac aacattgatg
     7561 ttatcacctg atgtcattat atttggtggc ggagtaatga aacaaaaaca cttaaaaaag
     7621 aaagtacaag ataagtttat tgagttgatc aacggatatg tcgctattcc cgatgttgac
     7681 aattatatta tgacaccaaa attgttagat aattctggta ttgtaggttg tttagcttta
     7741 gcaagagacg ttaaagaaaa atcttaattt ggaaaaaaga tcgtctcgac tatttgtttg
     7801 gttgatgcga tctttttttt caattagtaa ttgaagggac gcctaaaagt gaaaaaaaaa
     7861 atgaaagatg aagtattaga gtatatcaaa aataatttaa agtattacga tttttctgct
     7921 caagatattg caatgaaatt ttgtattaaa agaaatgtcg cttcccacta tttgaatcag
     7981 ttattttcag atggaaaatt actaaagaat gattctgtta gaccagtaat gttcaagtat
     8041 aatcaacaaa agccaaaaga ctgcttttct aagtttattg gagcagacat atctttgaaa
     8101 tccactatag ataaatgcaa agctactgta atgtatcccc ctaatggcct cccattaata
     8161 ataaaaggaa acagtggcgt tggaaaaagt tttttagcaa gtttgatcta tcagtatgct
     8221 cttgatagaa aagtaattca taatgacgca aaatttgttg ttgtgaattg tgcagattat
     8281 gcaaataatc cagagctatt gtcagcagtt ttatttggat ataaaaaagg agcctttact
     8341 ggggctgaaa aagatactgc agggatgcta tcttctgcta atggaggata ccttttttta
     8401 gatgaggttc acaatctaag tgcagaaaac caagagaaat tgtttcttct tatggattct
     8461 caaaagtatc gtaaacttgg tgaaagtgtg caatgggagt atgcaaatgt tcgccttatc
     8521 ttagccacaa cagaagataa aaatacctct ttgttagcaa cttttagaag acgcatccca
     8581 gctgaaatca ctctgccaga ttacaataat agaagtacat ctgaaaaaat tcaattatta
     8641 tttgaatttc ttaaagatga agcaattaca attgattcaa aaatattttg ttcgattgaa
     8701 ctttttactg atcttttatc gaaaacattt gaaggaaatg ttggagaatt gaggaatgaa
     8761 atcaagcttc tttgtgcaga aggttattta ggaaataaga gaaagtcttc aatttattta
     8821 ggggacaaac tagacagcgg tttttggata gatccagaaa ttagtataga tttaaaaaaa
     8881 atgtttctta aatcactttc tgaaattgat ttgattgaac tttttcaaaa tcacatttca
     8941 attgaagaaa gcatgagtca attaagagat agaatactta aagagtgtgc aggttcttct
     9001 gagtataatt atttagaaag tgacgaattt atagcattaa gaaactatgt tgttaataaa
     9061 atatcaccaa ttattgattc gacaggtcta tgtttattag atgaattctt ggcggatatc
     9121 agtctattta taatgtttat tgatgtaatt gaagaaacat caagaaattt tttgctgtct
     9181 aagttcagaa aatttcgtat gaaaaatgat aaacaaaaat tattggcaaa tgagatttgg
     9241 agtagtttag aagtcgaaga aagtaaacaa gaacttttgt tgaaatggat actttttctt
     9301 gtaaagaagt tctatgtgaa aataccagaa acccattgtc tgatagttat gcacggtaaa
     9361 ataacagctt ctgcgatcgc aagggaaaca aataagttgc tgaatacata tgtttatgag
     9421 gctttcgata tgccaattga aggtgagact agtgacttaa ttaacctaat caacaatttt
     9481 tgtaaaagta tagatacgac gaatggactc attctgctag ttgatatggg atcattggaa
     9541 caaatgtatg aaaaaattga atccaatgta ataggtgatt tggtaatttt aaacaatgtt
     9601 tctacagctt tagcgattga atgtgggatt caagtttgcc aaaaaaagcc aattagtcat
     9661 ttttaccaga tggattttga ttcgtttcaa gttaaagttc agtattataa aggattatca
     9721 caaaagaaaa atgtaatagt atcttgtctc tctggtgagg ggatttctga aaaagttaag
     9781 gatattttaa aacggtatct cgataatcaa gtggagattt tgatttttga ttttaacgca
     9841 ttaaagaaaa tagcaaagga aaaagatact atgattttta agaatacaat ttgtgttctt
     9901 tcaaccactg aattttacat tcaaggaatc gattgtttaa atttagaaaa tctaattaat
     9961 gggaatcaaa ccttagaaaa attaaataag tatatggact cggatagctg tgagttctgc
    10021 ttaaatgaat tagttaaact ctttactatt gaaggcgcta gtactaagct tcgcttttta
    10081 gattccaaaa aagtattcaa tgagatagaa aaagtactat atttgtatga aaaatattac
    10141 gatgtcaaaa tcccaagttt tctgagaatt aatctatttc tacatctttc tggaatgatt
    10201 gaacgaatta tgattggtga tggaataaca aatgaacatt tgaaagaggg agcgcaacta
    10261 tttgatactt ttttaaatgt atcaaaagat tttttttcag aaatcaaaga tatttactgt
    10321 attgaaatac ccaaaggaga gtatgagtta atctatacaa tttttgagca gactattttc
    10381 taaatagcat actagcgtct aaaaaaatga aagggtgtcc aaagtatatt tagacgctca
    10441 tttaattaat atttactgta ttttcccgct ttattggata atgttagttg gcacagtaat
    10501 tgcttatata aaagtataag aagaaaggag agaacaaaat ggcgttttgg caaacatttt
    10561 tagttgtgtt gtatggattt ttcattaact gggataagga agggcccaaa atcggaacct
    10621 cccaacctgt cgttgcaggt ttcttgaccg gacttattat gggagatatt caaactggac
    10681 tttatatcgg tgggactttg caattaatga cactaggtat tactagtttt ggtggtgcat
    10741 cagtaccgga ttatcaaaca gcagcattga tcggtactta tttagcaatc tcaactaacc
    10801 aggatgcttc tataggaata actttagcaa taccggtagc aatgttaatt gtacaactag
    10861 atgttctaaa gtggtcaaca aacatttttt ttcaacaaaa ggcagaaaaa ttcgcacaaa
    10921 aagaagatta tcaaaaatta gagtggatgc aatatttggc atcaattaat acaagctttg
    10981 tatctggaat tcctgttttg ttaactgtga tattaggccc aacgttagtg ggaagtgcaa
    11041 tcaattatat tcctgaatgg gttaccggtg gtttaaaggt agcaggggga ctattacctg
    11101 ctgttgggat aggaatgcta cttaaatatt tacctacaaa agattacttt gcctatttgt
    11161 tagttggttt cgttttggca gtttatttcc aaataccaat tttagggatt tcgttacttg
    11221 gcgctgcaat cgcactaatc gtatataaaa atagatcaaa taatactcaa gtagcaccag
    11281 ctgcaacagg aggttttgac gaagatgaat aagaaactga caaaaatcga caaacaagta
    11341 attttccggt ggattctcaa tggtgcaact tcattaaatt atgaaaaaat ggaagggttg
    11401 ggttatgcgt attctatgct tccttttatc aaggacacat ataaagatga tcctgaagga
    11461 atgaaacaat ccgttttagc tcacctacaa ttttttaaca ctacgccgta tacagcgcct
    11521 tacattattg gtatgaatgt tggaattgaa aaagaagaaa aaaataagtc tttggaagca
    11581 gtaagtgctc tgaaaacagg tctaatgggt cctttagcgg gaattggaga tagtgtattt
    11641 gtagttattc catggactat ttttggagca attgcagcta atatggcatt ggaaggtagt
    11701 tttgttggaa ttattttgtg gatactggca tcaattttat taaggattac tgcttatcct
    11761 ttataccttg ctgggaaaga atcgggtgcg agcctactaa ctcaaattga aacaaaatta
    11821 aagtctatta ctgatgcagt atcaatttta gggttaatgg tggtcggtgc actcattgcc
    11881 acagttgtaa aagtgaatgt tggctttgaa tttaaacaag gcgacttaac aatgaccgga
    11941 aatgaaatct ttgatcaagt tatgcctggt ttattacctg catgtgtagt agcaattgtg
    12001 tattatttgt taggacgaaa ggttaaacca gtttatgtaa ttctattaat cttagtagtt
    12061 tctattgcgt taagagcgtt aaatattttg aagtaggtgt tgaatatgga tgaaaaaatg
    12121 aaaggtatta tacatgttcg tattgatgat cgaatgattc atggacaagt agcaacacaa
    12181 tggacaaatc aattgagtgc taacagaatt atggttatta ataatgaagt agccaatgat
    12241 gacgtaaaaa aagctgtagt tcgcctcgct gcaccaccta atgttagaac ttcaataatt
    12301 acaagggaag tagcagttaa aaatattctt tctggtaaat atgaaggaca aaaagttctt
    12361 attgttgcag tttctccaat cgatgttaaa tttttgattg ataacggttt accaataaca
    12421 agtgtaaacg taggaaattt atcaagaagg aatggaacag aacgcatccg tccgacgata
    12481 aatattactg aagaagagag agaggctttt aaagaactaa ttagtgatgg agttgaagtg
    12541 acagtgatac aaactcctag agattcaaaa gaatttttaa aggattttat ttattaagaa
    12601 cagaggatga gtggatggag tttataatta catctcatgg aaatattgcc attggatttg
    12661 tagatacatt aaaaatgttt tttggcgata atttaaattg tcatgtggta acacttggag
    12721 atgcaggcat tgaagaattc cgtgaaaaca ttgaaaaaat agtttctcaa gtaaaaaatc
    12781 aagaagttat ggtatttgct gacttgattg gtggaacacc tttcaacgaa tttgctaaaa
    12841 gaagtgaagt atttcaaaat gggtttcaac ttcttggtgg catgaattta ggaattttga
    12901 ttgaggctgt caatttgaga ttacaaggaa aaaaaagcga tgatatcatc gaaaatctaa
    12961 gaaatatgaa tacaattgcg tgtcttgcag atatgcaaag acatactaac gaagaggatg
    13021 agtgataaat gcaaaaaatt ttttacaagc ctaaagattt ttggtttggg gattgcatgc
    13081 ctttttataa agatggaact ttttatctat ttcatcaacg agatacgaga aatcctaaac
    13141 ctttaactga tccttttggg tggtcactag ttacaaccac tgattttgtg aaatttgaag
    13201 aatacgggga agtaattcat cgtggtggca acgatgacat tgatcaatac atttacgctg
    13261 gaagtattgt ccaaggaatc aatgagtatt tagctttgta tactggacat aatcgcaaag
    13321 ctaagttgga tggaaaaact tcagaagtgt taatgattgc aagttctaaa gatttaattc
    13381 attggaaaaa ggatggcgaa gcagcaaaac ttgttcctca agaaggatat gataagaatg
    13441 attggcgcga tccttttgca atttttgatc aagatcatgg aaaatacgtt ttgatactag
    13501 gagctagaaa accagcaagt aagaaaaagc cgacggggag attggtctat tttgaatccg
    13561 aagatttaaa agattggaat ttcaaaggag actactgggc taataatgaa tttaacatga
    13621 ttgaaatgcc tgatatattt gaaattgatg gaacgtggta tttacttttt tcagagtatt
    13681 gtgaagataa aaagactaaa tatcgagtcg gagcaggatt attttcagat tggaaatcac
    13741 cagtagacga agctttcgac ggaaaagcct attatgcagc aagaacagtc ggaactaatg
    13801 aaactggccg ttttctaact ggctgggtgg caacaaaaga aggggagaac gatcaaaata
    13861 actgggattg gggcggtgca cttgttccac atcaaattat tcaaaagaca gacaaaactc
    13921 ttggtgttaa actgcctgaa aaaataattg agaattttaa agaaatcact ccattttcaa
    13981 gttttaagtt agagaaagaa tttggaaaaa aagaaagagt aattgttcct aaaatcgaag
    14041 attattttct atttgaaaca actttgacta ttacatcgtt aacaaaggag tttgctttaa
    14101 aattatttgt agatagtgat actcaagaag gatacgaatt tcgtatttca ttgattaata
    14161 atcagcttac tttcggaaaa actccgaact atccttggcc tcaaatgttt gataaggggc
    14221 tgcaacgacc actatttttg gaaataggca aagaatatga actaaagtta attgttgatg
    14281 atacgatagc tgttttatat attgataatg ttgctttaag tactagaatg tatgataaag
    14341 tcggaacagc attaagtatg actgttacgg agggagcaat caaggtagat aaactagact
    14401 attcaataaa ttatgaatgt ggattttaaa acaattgaag ggatgatgta agtgaaatta
    14461 aatggtttac aacatattgg aattccaaca aaagattttg gagcttcaaa aatcttttat
    14521 gaatccttag ggtttagtct gattaatgaa gaaatgaatg tgggaagtaa agtcggcttt
    14581 ttcgagttga atggaacgat aatagaaata tgggaagata aaactactga gtgtagagga
    14641 gccattgatc atctagcatt agatacggat gacatagatg aggtattcaa ttcaattcaa
    14701 gatttaggat atgaattatt agataaaaat attatggaat taccgttctg ggaaaatgga
    14761 atccgttact ttaatttcta cggaccaaat catgagatta tagagataag ccaaatgaag
    14821 aaataaatag ataacgaagt gctctaagtt ggtatgaacg aaaagtactt cattttttgg
    14881 tatcagcatt tcaatagttt aatgagaatt tactatttca aattaattca aagtgacagt
    14941 attttttact tatttggttt caaattttgt aatccttcct atttattgga atacactcca
    15001 cattttgtat acaagtcata tcatgtttta gcaaagctct taccaagcaa agttataatg
    15061 atgttttcca aagtttgatc tttcgatgga ggctaacaca tattttttgc aggacagcca
    15121 aaattagatg tatagaatag agtctgtgag gcgtatagac agtttattgt ctgtatgcct
    15181 ttttttattt tgaaaaattt ttagtatttt tcgaaaaatg ctcactccta gagtaagcgc
    15241 cccatagaac agtaccttac taacaaatgc acctcaagat atacttgagc tatcaagaag
    15301 tctggaggtt ttc
//
LOCUS       DAFEKH010000064        14879 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.067, whole genome shotgun sequence.
ACCESSION   DAFEKH010000064
VERSION     DAFEKH010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14879)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14879)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14879
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.067"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            418..1032
                     /locus_tag="LP386_002361"
     CDS             418..1032
                     /locus_tag="LP386_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL1919571.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            1805..3544
                     /gene="yfcC"
                     /locus_tag="LP386_002362"
     CDS             1805..3544
                     /gene="yfcC"
                     /locus_tag="LP386_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBL1919572.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            3701..4885
                     /gene="iadA"
                     /locus_tag="LP386_002363"
     CDS             3701..4885
                     /gene="iadA"
                     /locus_tag="LP386_002363"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HBL1919573.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            4996..5199
                     /locus_tag="LP386_002364"
     CDS             4996..5199
                     /locus_tag="LP386_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBL1919574.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(5300..5962)
                     /locus_tag="LP386_002365"
     CDS             complement(5300..5962)
                     /locus_tag="LP386_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1919575.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(5975..7477)
                     /locus_tag="LP386_002366"
     CDS             complement(5975..7477)
                     /locus_tag="LP386_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1919576.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            8025..9704
                     /locus_tag="LP386_002367"
     CDS             8025..9704
                     /locus_tag="LP386_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBL1919577.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            9831..10310
                     /locus_tag="LP386_002368"
     CDS             9831..10310
                     /locus_tag="LP386_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HBL1919578.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            10529..11209
                     /locus_tag="LP386_002369"
     CDS             10529..11209
                     /locus_tag="LP386_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBL1919579.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            11217..12548
                     /locus_tag="LP386_002370"
     CDS             11217..12548
                     /locus_tag="LP386_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBL1919580.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            12563..13525
                     /locus_tag="LP386_002371"
     CDS             12563..13525
                     /locus_tag="LP386_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HBL1919581.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            13636..13974
                     /locus_tag="LP386_002372"
     CDS             13636..13974
                     /locus_tag="LP386_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HBL1919582.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            14053..14760
                     /locus_tag="LP386_002373"
     CDS             14053..14760
                     /locus_tag="LP386_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HBL1919583.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
BASE COUNT         4774 a         2583 c         3203 g         4319 t
ORIGIN      
        1 tttttttgta ttttcttgct tgcacttgga taagagatta cttacaataa attcagatag
       61 aaacagctga ataaaaaaag gctccctgac ccttagttgg cgctaagaat cagggaatga
      121 ccagtcacac acatacaccc tgaccgatca ttttgccata gtcaatgcag tgcatcgacc
      181 taatttattg tacctaatct agggtgaaaa ttctacccct atgtagatat tttccatggt
      241 ctgcacgttg ttttatttgc tatgtcaagg tattgggcgt attcgttcaa tgcctttttt
      301 gtgtttgaaa cagcaaagac cacatgtgtt actgtctaac tactgttttt ttatgtactt
      361 ccttagatta ggcagctgtt tctattcatg tcaagtatag ctaggcggga gagataaatg
      421 agtttatgtt attttgacta ttatcaccaa ttggaagaga aattaaggat agaagagccg
      481 ctgatgcttc aagctggcac ttggatcgcg aaacaaatta atcaaggtgg tagattgcag
      541 atatatgcta gccgcacact aagtggtgta gcatttgaat tttgggatca aaccccggat
      601 cttgtaccaa gtatattgat tgaaaatcca gccggaggtg tctatgaaac gctagaaggt
      661 gcaggacagg caattattga tcagctttct gtcaaatcag aagacatttt tcttcttctt
      721 tcgaatgaag gaagaaaccc ggcaatcatc gaactagctc agtggatcaa agaaaatggt
      781 catccattaa tcattgttac tggatttgat ttgtcacgaa gtatcaaatc gcaacatagc
      841 agtggtttgc gattatttga atttgctgat ttggttttgg acaaccacgc caatttacat
      901 gatgcagtct tgactttgcc aaatctagat ccagcgatct gcggaacagc ctctcttgca
      961 acgatctttt tgctgcagca agttttgtat tttacagcaa aacagctagt ccaggacaca
     1021 agtggaaaat agttatccac atgttgacaa agttccttaa aaaaataatg ttccacataa
     1081 aaatggagcg tttgaaaaaa agaaaacgat tattaatgag gattaacaac gactactttt
     1141 tttgttttag ttattttaag atggatcatc tttgatttta agcttgtttt gtttaaagtt
     1201 tgttattttt ataagttgtt tcacagttat gagaaatgag ttataagaat atgtagtgtc
     1261 agaaaaataa aaagtagtgg aaaaagagac aagaaagaat ccatatggat tctttcttgt
     1321 ctcttaatac acgttgatga aagagtcttc cccaaaactc tttacaaagt aattatagta
     1381 catttgttat cattattgca atgaagttta cctgatataa caaaattgtc caacaggata
     1441 cctttttcta atagaaataa aatacacaaa aattgaagga tagataatgg atatttataa
     1501 gtgtttatta ttttttttgc aatgaaattc aatttttcaa tgattgtaaa atgaaaaaaa
     1561 caggacgaga ttttctctaa tctaaaaata aaaaaagaat tttaaggaaa aacagagaaa
     1621 taaaatactt aatataaatg gaaagagaaa aaaataatca tacataggag aaaaaaaaca
     1681 aaatagaaaa aagtgatttt ctaataaatt attcatgtgg aaatgtcatt tttactgtat
     1741 aattcatttg attatccatt ttttattcat caaaattact gaaaaaagaa aggaagaaat
     1801 aaatttgaag aaaacaaatt cttcaggaaa accgaaacgc gacttcacta aattatcgac
     1861 accccatacg tatgtcatta tttttggtgt agtcatcttt gcatggatac tgacttttgt
     1921 cgttccagca ggaaagttca gcacgcaaga tattgaatac aaagatgcaa atggcgaaac
     1981 aagtactcgt actgttttac gtcaagattc cttccgttat gcttacgagc tggataagtc
     2041 gtatgtgttt gatcaattag aagaactgca agatcatcca gcagaacgtg aaaaactgga
     2101 tgttccggaa aaaggattgg aaaaagtcat tgctgacgga gaaaaaaatc ttacgcagga
     2161 aaaactagat gaaatctcct tgacagatga tgtgctttac gatcagtacg gcgaaaatat
     2221 ctatgatact tctaaaaaat tgcataaaac agccaaaata tggggaacag atgattttgg
     2281 cggctttggt ttcttaaatt ttgtttttga aggactagta tctggagata agtatggatc
     2341 tgctgtaggg atcgctgcat tgatccttgt tgttggaggt gcttttggta ttattatgcg
     2401 taccggagcg atcgacgcag gtatctatgc gtttatcagt aaaactaagg gactggagcg
     2461 tttagcttta ccgctattat tctttgcttt ttcattcggt ggcgctacat tcgggatggc
     2521 agaagaggta attccattct caatggtgat ggttccattt gtcattgcgt taggatatga
     2581 ctcgatcgta gcagtaaccg tgacttatgt cgcatctcaa gtcggaaatg cgacctcttg
     2641 gatgagcccg tttagcgtag cggtggctca agggattgct ggaatccccg tgttgtctgg
     2701 tgcgacattc cgattgatta tgtgggtagt tgttactgca ttagccgctg gttatatgat
     2761 gatatatgca gaaaaaatcc gtaaaaaacc agaaagttcg ttgacttaca aatcagatga
     2821 ttatttccgt tctcatatca aaaagacatc tgatgaaaat aaaaaattca tgcttgggca
     2881 taaattgatc ttattagaga tgttagttgt ccttgtctgg atcgtttggg gcgtgactca
     2941 aaaaggctat tacattccag aaatcgcttc tcaattcttt gtgatgggat tagttgctgg
     3001 aatcattgct gttcttttca aattagatgg aatgaaagtc aatgacatcg cttcttcttt
     3061 ccaatctggt gcagctgatt tagctggtac agcaatcgta gtaggtatgg ccaaagggat
     3121 tcttcttgtc ttgggaggat ctgatgcatc tgttccttca gctttgaata cgattttgca
     3181 tgggatcggg acggcgttga ccggtgttcc agctgtcatt ggtgcttggg cgatgtacat
     3241 cttccaaagt ttgttcaact tggttgttac atcaaattca ggacaagcag ctttgactat
     3301 gccaatcatg gctccactgg cagatttagt aggtgtatcc agacaagtag cagttcttgc
     3361 ttatcagctt ggttcaggtt ttatggacgc ttttacaccc gtatcagcca gcttgattgg
     3421 tgtgctaggt gttgcacgga tcgaatgggc aaaatgggca agattccaaa tcaagatgca
     3481 aggattcctg tttgttttag gaactatttt catcatgatt gccattgcaa taggtctgca
     3541 gtagtactgg agacctgtaa ataaaaaagt aatccaaaca gtagataagg actccaagaa
     3601 ccgtcatttt acggtaaaat caaaggagta aagatcctat cgtttggatt attttttaag
     3661 atcctatcat cagttatact taaagaaaga ggaaaaatgt atgaaaatca ttcgacaaat
     3721 tgaagtgttt gcaccagatt acttaggaaa aatggatgta ctgattgccg gtgggaagat
     3781 tttggctgta gaagaacagc tagaaggcgg ctacgaagga gtggaagtag aagaactttc
     3841 aggtgaggga aaagtactaa ccccgggttt cattgactgt catttccata ttttaggtgg
     3901 aggaggagaa ggcggttatc aaaatcgaac gccagaagtc acattgagcc aattgactac
     3961 agctggtgta acgacagttg tcggttgttt gggaacagac ggagaaggta gagatatgac
     4021 tgcgttgatc agcaaagcga aaggtctgga agcagaagga atctccactt atgtatacga
     4081 aggttcgtac cgattgccgg taaaaacagt aacagattct atcatcaaag actttttgac
     4141 aattgataaa attatcggaa tcggagaaat cgcagtatcc gatcaccgtt cttctcagcc
     4201 aagttttgaa gagttcgctc gtgcagtagc agatgctcgt gtaggaggca tgttatccgg
     4261 aaaagctggg atcatcaatg tccacttagg cggaggaaaa agaaagctag agctattgac
     4321 acgaatcgta gaagaaacag aaattccgat cacacaattt ttgcctactc atgcaaatcg
     4381 cacaccagaa ttatttgaag cttgcgtggc atttgccaaa cgtggtggca cgattgactt
     4441 cactgctagc gaagatcctg atttttggga gaagacagat ggtgaagttc gcttcagcaa
     4501 agcactgaaa cgattgatcg aggaagatgt ttctttagat aatttcacga tgacctcaga
     4561 tggacaagga agcttgcctt attttgatga aaacaatcat ttcctagggt taggagtagg
     4621 aagtgccaag gcattgctag tagggatcaa agaagctgtg caaaaagaaa gtatcccttt
     4681 ggaaatcgcc ttacgagcta taaccagtaa tccagcacgt atattgaaat tggataaaaa
     4741 aggaaaaatc gaaattggtg ctgatgcaga tctgtgtatc ttggataaag aaacgcttga
     4801 tattgataca gttatcgcta aaggagaaat aatggtccaa gaaaaagaag tcaaagtatg
     4861 ggggactttc gaaaaaagtt tttaatcaac agctctaact atctttttta gaaaacgagc
     4921 gttctgtttg tctgtatctg ttgttgatgt taccctgaag gtagatcaat aaacaaacta
     4981 agaggaggaa gcacaatggc agatttaaaa ggacgttcta aagatatgaa agataaagta
     5041 gtcggtgaag gaaaagaagc atacggcaaa gcaacagacg acaagagcaa agaaacagaa
     5101 gggaaagcac aatcactagg tgctgacatc aaagaaaaag ctcgaaattt aggcgacgaa
     5161 gtcaaagaca agttttctcg aaaagacgaa aaaaaataaa aaccacttat tactaattga
     5221 atcaagcaaa taaaaaatcc gaaccatatc tgcgagacag atatggttcg gattttttat
     5281 ttgatcatta tcctgttttt taaacttcga ttttttgaaa ttttttattt tttagttcaa
     5341 agacttcatc acagcttttt gctacttcaa tctcatgagt cacgatgata atacagcgat
     5401 tttgttcatg ggcgatttct tggaaaagtt tgacgatatc ttgtgaagtt gtttcatcta
     5461 gatttccagt aggctcatcc gctacgatta gttgatgttc acagcagata gcacgaacga
     5521 tagcgactcg ctgctgctga cctcccgaaa gtttggtcac ctgttttttt gctaatattt
     5581 catcaattcc tacacgagcc agtcgatcta aagcaacttg tcgataattc tcttgcttgg
     5641 tcttagtgat ttccattgct gctatgacgt tgtctagagc cgataaataa ggaagcaagt
     5701 tgtaagcttg gaaaataatc gagacatcat ttttacgata acttcttaac ccgattttgt
     5761 tcagtgaacg atcttgatag tatacctttc cttcttttgg tgcatctagt ccagaaataa
     5821 gcgaaagaaa agtcgttttt ccagaaccac ttgctcctaa aatagcgtac atttttccag
     5881 cttcgaaatt cagttctaca tctttataaa gcgcatcttg cggatcttga taccaaaatc
     5941 ccaattgttc tgtccgtaac atcaaattcc tcctttagtt taataggatt tttcttgggt
     6001 ttaatcttaa tatccctata gaagctaaaa agacagaaaa cagactgatt ccaaatgcta
     6061 ctccggctaa tagtcccaat tgtgcaggtt tgacattgat ttccaattcg ctgacttgat
     6121 cagaaacagc aaatggatta ttcgtggttc cttgttgacc atcgcgttga ccgccttgtt
     6181 cttgtctgtt acctggcatt tgtccaccgc caggagcttg ctggttttgt gtcgtggttt
     6241 ctgtctgttg gtcaagtagc tgctgtccca cggcattcgc gacgacgttt ccgctaagcg
     6301 aagcaactcc taatgcaaga atcatacaaa tagccacttc ggtaaacaat tggagaatga
     6361 ttttacttct ggattctcct aaagatagca agacgcctaa ctcatgccga cgctcccgaa
     6421 tggtaatcat aatgatcaga gtaagtatga taataccggc tacagccact agtaaaacaa
     6481 catttttaga aaaacttgcc acgttgttta aaggttccaa cattgactga tacatggaat
     6541 catttgattg taagctaaat gtatctgtgt cgatcagctt ctcagcttct ttgagaaact
     6601 catccatttt atctggatca gatagagtgt aaatagcaga atctatcgtg ttatcgtcag
     6661 atgtcccatt tagttcattt gcaaaagtgt aagaagtgta aagtgtattc gacggattca
     6721 tgaagttgaa tttcataccc atactgccgc ttgtttcgct ggattcataa attcctttga
     6781 tcgtcatttc ataagtggta tcttcatctt cagtactcgt gattgtgaaa gtatctccga
     6841 ctgccaggtc atttgtttct gctagagtag aatcaatgac tacattgttt gtgcctttgt
     6901 cgctgtcatc tattccttca ccatccgtga tttttgctgt tccatcagaa aaattactat
     6961 tttgtgcagt tgctgacaca ccactgattt gaaagtctgc ttgagtcatt tgcggattcc
     7021 cgcccattcc tccagcaggt tcaccgcctg catcagtagt ttctgaactg tcttcacttg
     7081 aatcagaact agtgatggca gttattccat cttttgccat agctgaggcg gaactttcaa
     7141 aggaataact ctttacatta tctaattcag ctattttttc cgcgtccgtt aaggaaactg
     7201 gtgtaagaga aaaactgcct ggatctggac gttcttcagt ggtagaaccg cttgaagaag
     7261 tttgttcctg ttttttaaat gaagcttctc gattggcact taaagtcact gttgctccaa
     7321 cttctttttg tgcttgattc gctgcttctt ctgcagcgct tcgaatcgtg aggccagcta
     7381 gcacaaaaat aagaatggct gtgaacacgg caaacaataa caatgaacgt ccccatttta
     7441 cttttgtact tttccatgca cgtttcataa aattcatatt ttgcatccct cctagtagat
     7501 gcatttgata atagacaacc tatcttaaag ctagcttaaa tcttatgctg tttgcacacc
     7561 atcaacatga ggttctgtat atataaaaag tcactatagt tattgcaaaa aatgtggtaa
     7621 aatgaaaaaa gtatgtttca aaccgacgaa gaagaaatga aagaggaata gcaaaagaaa
     7681 tcctagatgc tacagaggga tttttacgtg catagttgtt ctaacaattg ctgatactag
     7741 cgatttagtt tatttgttgt ataataatgg ggaacagctg aatacttata taagtattct
     7801 ggctatagcg tttcgcaaaa gatccatttt gttaatgaag tatatccaaa ataaaatgcc
     7861 catccaactg tcagaacgcg gatgtgctgg taattttcct gctgattctc cataagttga
     7921 gaaatagtga ttttgcatat gcttcattgg aatggctcat atatttagat aaagaagaaa
     7981 atcgacatct ttaaacttgg atgtcataag aagaggtgaa gtttgtgagt accattaaaa
     8041 ttatcccatt aggcggcgtt cgtgaaaatg gaaaaaacat gtatgtcgca gaagtgggcg
     8101 aggatatttt tattttagat tgtgggctaa aatatcctga aaatgagttg ttggggatcg
     8161 acgtcgtaat ccctgatttt acgtatttag aagaaaacat tgatcgtgta gctggtgtct
     8221 ttttaacaca tggacatgca gatgcgatcg gggcacttcc ttacttgttg tcaaaaattt
     8281 ctgtaccagt attcgggaca gagttgacga tcgagttagc aaaattgaat gtcagtcgta
     8341 atgaagcagc caaaggattt aaggatttcc atgtggtaga tgagcataca gaaatagact
     8401 ttggtgaaac agtagtgagc tttttccgta ccactcatac gataccagat tcagtgggga
     8461 tcaatctgaa aacaaaagaa ggtagtatcg tttatacggg agattttaaa tttgaccaaa
     8521 cggctatccc aatgtatcaa acagattatg cacgattggc ggaaatcggc aaagaaggag
     8581 tcttagcctt actaagtgaa tcggcaaatg cagaaaatcc tcagcctgta gcttctgaag
     8641 cccaaatagc agatgaagta tttgatacga tcaaatattg ggaagggcgt atcatcgtcg
     8701 cttgtgtagc aagtaatttg caacgagtgc aacaagtatt ggatgcagca gaaaaagcac
     8761 aacgaaaagt tgtcttgact ggtcaagatt tcgaacgaat tattcgcaca gcgatgcgtt
     8821 tagaaaaact tcaattacca agtgaagatc tgcttgttac gttgaaagac atgaaaaact
     8881 atgatccaga agaactgatc attttagaaa ctggccgaat gggtgaaccc atcaagtctc
     8941 tgcaaaaaat ggcaaacggt acacaccgta atgtcaagat tgaagaagga gatttggttt
     9001 atatcactac tacgccaagc atcgcgatgg aaaccatcgt ggcgaaaacg gaagatatca
     9061 tttatcgagc tggtggaaca gtgaagttga tctctgagaa tatgcgcgtt tctggccatg
     9121 ccaatcctaa tgacttgcaa ttaatgatca atttgatgaa accaacatat tttgtgccag
     9181 ttcaaggaga gtatcgtgaa ttagctgctc atgcagattt ggctcatgca gtagggatgc
     9241 catacaaaaa tatctatatt actggacgcg gagacgtgct ggaatataag aacaagcgta
     9301 tgagtgttgc aggaactaca agtgcagaaa atgtaatgat tgatggatta ggcataggtg
     9361 atatcggaaa cattgtttta cgtgatcgaa aaatcttgtc agaagacggg attttcgtag
     9421 cggttgtcac tatcagtcgg cgagaaaaga aaatcatttc aaaacctcaa attacttcac
     9481 ggggattcgt ttacgtaaaa gctagccgtg atctgatgaa agaaagcagc aatatgattg
     9541 aaacaatcgt tgagaaacat ttagaaagca atgattttga gtggagcaaa ttaaagcaag
     9601 acatccgaga tcaattaggc cgttacttat ttgaacaaac aaaacgccgc ccagtgatct
     9661 tgccagtcat tatggaagct actcaacgtc gaaataaaaa ataaacaaaa agagtaagat
     9721 gaacctctct atagagtgct cgtcttgctc tttttttgcg aaaaacaaat aatttttgaa
     9781 tacagcatcc ctcgctttat aataaacgat agaataaagg gagtgaatca atgatgagtc
     9841 aaacaaaagt cgaacgttat ttagaagaac aaaagatcag ctatcaacca cttgatttta
     9901 gtcatgtggt agaagaatct ttcacagaag aactacaaaa aagagggatt gatccagctt
     9961 tgatatgtaa aactctcgta gtgaaaggaa acaaaactgg ggtgatcatc gcattgattc
    10021 ctttgaacga tcacttagat tacaaaaaaa cgagacaagt gacgaaagat cgtaaagttg
    10081 gttttcctgg aatggatttt gtattaatgc atacaggata tccccacgga gcaaacaccc
    10141 ctattggaat aaaactcgca catcctgatt attgtttttt agcagacagt tctttaaaag
    10201 aaaaagaaga agtaattgtg tcaagcggtg aaatcgggag aagccttcgg ataaaagtag
    10261 ccgatttaga aaagatcgtc catcctattt acgctgattt aattagttaa gggacgagaa
    10321 gagaagctaa gcagagcaga gacctcaaac ttgagattat atctgcttgg tacttggtgc
    10381 atcctgtatt atctgttaca attgctttgt acatactgta ctatcaatcc aatgaaaata
    10441 tatttagcag ctatattttt tcattgatgt gcaagtgatg aaatcgtttt taataaaaaa
    10501 gatacagaga aaacgcgagg tgtaaaatat gaaaattacg tatcatggac attcctgttt
    10561 aacaattgaa atggaaaatg gccaacgcgt gatgattgac ccgtttatta caggaaatcc
    10621 attgacagac ttaactgcag aagaagtaaa gacagattgg ttgctgatta ctcatggtca
    10681 tagtgaccac ataggagata tgattcctat tgcaaaagaa aatcaagcca caattatcag
    10741 tattgttgag attgctgatt atgcgaacag cagaggagta gattcattcg gtatgaatat
    10801 cggtggaaaa catgcgtttc cattcggcgt ggtaaaattc gtacatgcac agcatagttc
    10861 aagctatgaa gtagacggta tcgttcagta tatgggcgag cctagcggaa ttattattca
    10921 agcagaagga aaaacgattt atcatgcagg ggatactgct tatttcagtg atctaggatt
    10981 gcttgcagaa gaattcgata ttgatgtcgc tttcttgccg attggcgata actatacgat
    11041 ggggccagaa gatgcagcaa aggctgcgca aacaattcgt gccaagaaag tagttccaat
    11101 ccattacaat actttccctg tcattgaaca agatcccgaa tcttttgtag agttactgga
    11161 agatagtgaa ggaaaaataa tgagcgtctc ggaaacgctg gaagtgtagg cagaaaatgg
    11221 cgacaaaaca tgatttgatt ttagaatata ttgaaagttt acctgttggc aatcgaattt
    11281 ctgtaagaag catcgcaaaa gaattgaatg tcagtgaagg aacagcgtac cgtgcaatca
    11341 aagatgcaga aaatgtcgga ctagtttcaa caattcaacg agtagggacc atccgtatcg
    11401 aacgcaaatt aaaaaaacat attgaacgtt tgacatttgg cgaggtcgtc aggatcattg
    11461 aaggggacgt tttaggcggg gcggcaggat tagacaaggt cttgaataaa ttcgtcatcg
    11521 gcgcgatgac taaacatgcc atggaacgct atattacgcc aggatcacta atgatcgtcg
    11581 gcaaccgggc ggaagtccaa aaattagcat tggaagatgg cgccgcagta ttgatcacag
    11641 gaggattcaa tacgactgct gagattgcaa agctagctga tgatcttgaa atgccgatct
    11701 tacgcacctc ttatgataca tttacagtcg caaccatgat caaccgagcg ttaagcgacc
    11761 aattgatcaa aaaagatatc atgcttgtca gtgatatcta tatgccagct gaaaagactc
    11821 attatttgca gcagacagat acgatttctg attatcagcg tttgtcagaa gaaacgcagc
    11881 attcgcgttt tccagtcgtc aaccgccatc atcgtttgat ggggattgtt acggcaaaag
    11941 atgttttagg gaaatcgcca aaccagatca tcgatcgggt gatgacgaaa gaaccaatca
    12001 gtgtaaagaa aacaatgagt attgcctctg ttagccatca aatgatctgg gatgggctag
    12061 aagtcatgcc ggtcgtttcc gatgacttga cattggaagg cttgattacc cggcaagatg
    12121 taatgaaagc gatgcagctt gtccagcgac aaccgcagat tgcagatacg atttcggatc
    12181 agatatctgg aaatatccat acgattgata ctgaccgtga aggaaatcgt ttggaaaacc
    12241 ctaagttcaa attcgtagta gcaccacaaa tggtcaatgg cgttggaacc atttcttttg
    12301 gcgtacttag cgaaatcatt tctgatgtcg cacaaaaaac aatggtgatg aaccaaaaac
    12361 gaaatatctt gattgaacaa gtgaacctac attatttgcg gctgatccaa ttggaaagcg
    12421 aattagacat tcgtccacgt gtattggaaa tcggcagacg ttccgctaaa ctggatatcg
    12481 aagtgtttat tgaaaacacc atcgtttcca aagcaatcgt tgtttgtcaa gtaatggaac
    12541 gttcttagaa agcaggagtg aaatgacagt acagcaagaa atagtagata caataaaaaa
    12601 atacgataaa atcattatcc acaggcattt gcgccctgat cctgatgcat taggatcaca
    12661 agtaggatta gccgaactat tacgggaaag tttcccagaa aaagaaatac gtcaagtagg
    12721 tgaaacgatt gaagggcttc gctttttagc agaaatgcaa gaagttgaag atgtcttcta
    12781 ccaaggagcg ctagtcatcg tgactgatac agctaattca cccagaatca gtgatcaaag
    12841 atatcagttg gcagaaaaac tgatcaaaat cgaccatcat cccaatgatg acccttatgg
    12901 agatcttgtg tgggtaaata caaaagcaag tagctgtagt gagatgattg cagaatttgc
    12961 tttgatgttt cctgaatctt taaagatgaa cgttaaggct gcacggttac tttatgcagg
    13021 aatcgtcgga gatacagggc gctttttgta tccctccacg acgtcccgta cattagagat
    13081 tgcttcgata ttgagaaatt atccatttga tgcaagtgct ttgaacagag agattgaaca
    13141 aatgccgatg aaagtcgcta aactttccgg ttatctttat caaaatatcc aggtggatga
    13201 aaatggtgca ggaagaataa tccttccgca agaaattctt gataaatatg gaatcgatga
    13261 ttcagagaca gcttcgatcg tttcacttcc tggagtgatt gacgaagtgc tggcttgggg
    13321 gatttttgtt cagcagcctt cagggtatta ccgcgtacgt ttacgttcta aggggccgat
    13381 catcaatgaa ttggctaaac gccatcatgg aggaggccat ccattagcaa gtggtgcgaa
    13441 tgcaaaagat ttagcagaag tagaggaaat ctataaagag atccaagata tatgccaatc
    13501 gtataagagc agaaaaacag aatgatactt cgttcgaaaa cgtgcctttt gtagtaaaaa
    13561 tcacaaatgt atcttttcaa gatcttcttt ttccgttaca atagtgctca ctaaagattt
    13621 taaaggagaa agaagatgac attaccaaat tgcccagaat gtggctcaga gtacacatat
    13681 gaagatcgag gcttgttgat ttgcccagaa tgcgggaacg aatggaacaa agaagaacaa
    13741 gaaactgtca tagaagacgg attagtggta ttagatgcaa atggaaaccg tctgttagag
    13801 ggcgatagcg tgacagtgat taaagacttg aaagtaaaag gtgcgtcagg tgccattaaa
    13861 caaggaacaa aagtcaagaa catccgttta gtagaaggcg atcataatat cgattgcaag
    13921 gtagaaggat ttggaccgat gaaactgaaa tcggaatttg tgaaaaagaa ttaaagaata
    13981 ttcaaggtct tttcacattc ttttcctact actaatgata aaataaagta aacgaaaagg
    14041 agtgaaacga aaatgtatgg ttatggaatg tatggttttt tagatccgac atttcttttg
    14101 gtcattcttg gattagttat ttccggaatt gcgtcagcgt acgtcaatag tactttccga
    14161 aaatacgatc aagtgagaag caaaaacaat gtgactggta cacaagcagc acaatatata
    14221 ttacaaagtc aacagataaa taatgtcggt gttcaacaaa ttgccggaga tctcacagat
    14281 aactacaatt caggtaataa gatgttgagt ttgtctcaag caactgcaca gtctacttca
    14341 gttgctgcga taggtgtagc agctcatgaa tgcggacatg cggtacaaga tgcttcgggt
    14401 tatgtcccat tgaagattcg tgcagcactt gttccagcag ctaactttgg ttcgatgatt
    14461 tcgttcccct tgattatggt aggtgtattg cttagctgga actctacgtt aatcaatatc
    14521 gggattttcg ctttttcttt agcattactt ttccaattgg tgacattacc agtcgaattt
    14581 aacgcgtctc ggcgagcaat ccaaattttg agtgaaggcg gactactgac ggaagaagaa
    14641 gtaccgatgg caagacacgt attatttgca gcagcactga cttatgttgc agcagcgctt
    14701 tcgacattcc tgcagctgtt gcgcttgatc ttattgttcg gcggcaaccg aagagattaa
    14761 aataaagaag ttgtgaaatc agcgctttga tctgagctaa taccgagagt tagctgattg
    14821 aataccattt atttggaata agggctcttt gtcaataagg actgatgggt tgtacaaaa
//
LOCUS       DAFEKH010000065        14750 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.068, whole genome shotgun sequence.
ACCESSION   DAFEKH010000065
VERSION     DAFEKH010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14750
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.068"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(555..917)
                     /locus_tag="LP386_002374"
     CDS             complement(555..917)
                     /locus_tag="LP386_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919584.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(991..1371)
                     /locus_tag="LP386_002375"
     CDS             complement(991..1371)
                     /locus_tag="LP386_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HBL1919585.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1435..2628
                     /locus_tag="LP386_002376"
     CDS             1435..2628
                     /locus_tag="LP386_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBL1919586.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            complement(2705..3289)
                     /locus_tag="LP386_002377"
     CDS             complement(2705..3289)
                     /locus_tag="LP386_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL1919587.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            3490..4488
                     /locus_tag="LP386_002378"
     CDS             3490..4488
                     /locus_tag="LP386_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBL1919588.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            4600..5109
                     /locus_tag="LP386_002379"
     CDS             4600..5109
                     /locus_tag="LP386_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HBL1919589.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(5139..5798)
                     /locus_tag="LP386_002380"
     CDS             complement(5139..5798)
                     /locus_tag="LP386_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HBL1919590.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(5800..6564)
                     /locus_tag="LP386_002381"
     CDS             complement(5800..6564)
                     /locus_tag="LP386_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HBL1919591.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(6572..7249)
                     /locus_tag="LP386_002382"
     CDS             complement(6572..7249)
                     /locus_tag="LP386_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HBL1919592.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(7286..8671)
                     /locus_tag="LP386_002383"
     CDS             complement(7286..8671)
                     /locus_tag="LP386_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBL1919593.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(8881..8965)
                     /gene="ffs"
                     /locus_tag="LP386_002384"
     ncRNA           complement(8881..8965)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="LP386_002384"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(8988..9503)
                     /gene="tadA"
                     /locus_tag="LP386_002385"
     CDS             complement(8988..9503)
                     /gene="tadA"
                     /locus_tag="LP386_002385"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HBL1919594.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            9610..10467
                     /locus_tag="LP386_002386"
     CDS             9610..10467
                     /locus_tag="LP386_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1919595.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYRYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(10548..10883)
                     /locus_tag="LP386_002387"
     CDS             complement(10548..10883)
                     /locus_tag="LP386_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919596.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(10950..12320)
                     /locus_tag="LP386_002388"
     CDS             complement(10950..12320)
                     /locus_tag="LP386_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HBL1919597.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(12398..12934)
                     /locus_tag="LP386_002389"
     CDS             complement(12398..12934)
                     /locus_tag="LP386_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL1919598.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            13243..14724
                     /locus_tag="LP386_002390"
     CDS             13243..14724
                     /locus_tag="LP386_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1919599.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
BASE COUNT         4527 a         2929 c         2396 g         4898 t
ORIGIN      
        1 ttcatcggga gtgtttcccg attcgttttt ggctgccgta gcaactttta tatcatatca
       61 gagagacaag cgattgtcaa ctctttttta aaagtttttt tcgatttcgt ttttcgaaat
      121 ctttcagcaa ctcatttatc gtaacttatc gtttgttatt tgtcaagaac ttttttgaag
      181 tttttttcga tagaatcaag cttcgcaagt ggttcttttt taacgactca gttatcttat
      241 catgtcgtta gtaacatgtc aataactatt ttttaaattt tttagaaatg tgatataaca
      301 tccacttcag aatcaacgct gttaaattta tcatgtattt cttccttggt caactataaa
      361 ttaagcatta ctttgtgaaa tgatttttcg atcaattatt attattcgtt atacaaccgt
      421 tttcaacata ttttgaaaat aaaatgcact aaaaaactat ctttagcaga acatttcatt
      481 gtattttttg gaccaaacaa taaaaaaaga agtttgaaaa aaattcaaac ttctttgttc
      541 gcttaatctg tattttagaa gaaaggcact ccctctactt cgtaagttcc aagaacagag
      601 cgcatttgac ctggttcttc ccaaatatat ccttcgccta attcttctct ttgattcttt
      661 tgttcagttt caaagacaaa caacggaaca ttttcctctt taatatgtgt atttgtcaat
      721 tccatcaaac taatcttgct aacatcgata tgaactattt cttttaagaa attaagtata
      781 ttcgctaaac cagtctttcc ttcagaaagt tccgctaacg caaattccaa cttgtcatca
      841 attgaatgga ccaaaaattt tttagtacca tcctccaaat gcaacataat tgtaccagca
      901 actcttttgc ttgccaaaat ttccacctcg atcaacttgt tctatggctt acataaaaat
      961 tctagcacat tttcagaaaa aatacacttt ttatttctta ttttctttcc gttctagttc
     1021 agataatgct tcttctatcc aaataggtaa ctgctccgca atagtggtaa atccgatctt
     1081 acgattttta ttcgtgaaat acctttttct gcgatatgga acagctggat ttgttttttc
     1141 taacgttctt aaagataaac tgattttttt ggaatattca tcaatgtcga tgatctgaac
     1201 tgttactggc tgtccgactt ttaacaatga atggatattt ttcgtataac cggattgtac
     1261 ttctgaaaca tgaataagtc cttgcgtctc gttatcaaga gaaacgaatg cgccataagg
     1321 ctgtatccct gtcacttttc cttcaattat ttgtccaatt ttataagtca tctacttccc
     1381 tctcttcgca tttatcatta tactgtaaat agctcaaaaa aagaagcgac gaaaatgact
     1441 ggaggtctta agatgatcga atttgataaa cagatttcaa gaaaagatac agaaagtgta
     1501 aaatgggacg caattgctga gacatatcaa atggatgact tacttccttt gtgggtagca
     1561 gatatggact tcttgtctcc cggtggggta gctaaagcgt ttagtgaata catcaaacat
     1621 ggaatctttg gttatgccac tctgtctgat aaactatatc aggctatcat tcattgggaa
     1681 cgccaacacc atgctgtgga gttgacgaaa gaaaatatcg tttttacaag tggtgtgtta
     1741 accagtttag ctgcagcagt acaaactttt acaaaaccag gcgattctat tttgattcat
     1801 gacccagttt atcctccatt ttcctctatt atagaaacaa atcaacgtca catcgttcga
     1861 agctctttgc tagaaaaaaa taatcatttc atcatggact tgtctgacat ggagaaaaaa
     1921 atcgaagaaa acaatgtaaa agcaatgatt ttatgcaatc ctcacaatcc tggagggcgt
     1981 gtttggagca aagaagaatt gaaacagtta agcgaattgt gtttaaaaca tcaagtgatt
     2041 ctgtttagtg acgagatcca tcaagattta actttattcg atcatacatt tacttccatg
     2101 ctaacgattg atcctaattt agatgatcta ctagttgctt ttacttccgc aaccaagact
     2161 ttcaatctag ctgcaatcaa aaattcaatg gtatttatca aaaatccaga gatgaaagct
     2221 gattttgaaa aacatttagt gatgaaccaa cagcacgaaa tcaacacttt tggactgatt
     2281 ggaacccaag cggcttatga gacgggtgga gaatggttaa gccaactgat tccttatcta
     2341 gaaaaaaatg ttcaaacagt taatcagttt tttgaacagt atcttccgaa agtgagaata
     2401 atgaaccctg aaggaactta cttaatgtgg ttagatttta ccgcctatat ttcagacgac
     2461 caagaattgg agaacactct tgttcggaaa ggaaaagtcg tattaaatcc tggcatcacg
     2521 tttggtcctt ccggtcatgg gcatatgcgc ttgaatattg cttgtccaga agaaacttta
     2581 ctggaaggac ttaatcgaat caagtatgct ttagagacaa tcgattaaat catttattca
     2641 aaataaaagg acgagacctt actaggtttc gtcctttttc ataattactc cgtaccatac
     2701 caaactattc tgaaatttca attgtttcaa tcactacatc atgtacaggt cggtcttgtg
     2761 gaccacgttg tacatttgcg atttcatcta ctgtgtccat cccttctagt acatgtccaa
     2821 agactgtatg tcggaaatct agccaaggag ttccgccacc tttatacgct tcaatgattt
     2881 ctgatgggaa tccagcacct tctagttgtc caagcatatt agctggcaca tttgtgttat
     2941 ttacaataaa gaattggctt ccgtttgtgt ttggacctga atttgccata gataaagctc
     3001 cgcgaaggtt gaacagttca cgactgaatt catcttcaaa actttcgcca taaatacttt
     3061 cgccacccat tcctgttcca gttggatcgc cgccttggat catgaaatca ggaataacgc
     3121 ggtgaaaaat cacgccatca taataacctt ttttggaaag ttcaatgaaa ttttgaaccg
     3181 tcttcggtgc tagttcaggg aataattgaa cagtaatgtc accacggttt gttttgataa
     3241 cagcttttgg tcctttttca ctttttaaat ctagttgtgg gaatgccata ttgtttcctc
     3301 ctaatatttg catacttcat aataataata acataatacc taacctctcg taaaaatact
     3361 agatttgttt tcttttattt ttcatcacta gatacattct ataacttacc gtttcgattt
     3421 cgaattcaaa catttttgag aagcattctc aattaaattc tgctatagtg tgaaaaggga
     3481 ggaattttta tggaaatcta tgacattaca atcatcggtg caggtcctgt agggatgttt
     3541 gccgcttttt acgcaggaat gcgccaagct aaaacaaaaa tcattgacag tctacctcaa
     3601 cttggtggtc aattagcaac tttgtatccc gaaaaatata tttacgatat tcctgggtat
     3661 ccagcaataa aagcaagtga attaatcgat caattagaaa aacaattaac tacttttaac
     3721 catacattcc atttaaaaga agaagttctc tcgcttactc gtgaagacga agttatcgag
     3781 attactacaa ataaaggcat ccattattcc aaagcagtca ttttagcttt aggaaatggt
     3841 tcattccagc caagaaaatt gaatttagat aatgctgaat catttgaaaa ccacggattg
     3901 gattatttcg tgaatgattt gatgaagtat gctggaaaaa aagtcgctat tgctggaggt
     3961 ggtgattctg ctatcgattg gacgttgatg ttagagccta ttgcaagcga agtttacttg
     4021 attcatcgtc gcccggaatt tcgtgcgcac gaacatagtg tatcacgctt gaaatcttca
     4081 tctgtcaact tgcttactcc ctatctcatc gatggattat caggcaataa tggggaactg
     4141 acagatatcc ggttaaaaaa agtgaaaagt gacgagacga ttgatttgat gattgattct
     4201 ctgatcgtca attatggatt ctcttctaat ttagaacatc tttcttcttg gggacttgat
     4261 agtaccagaa atgccattac tgtaaaatca gatatgtcta cttctattcc aggcgtttat
     4321 gcagctggtg acatctgtac ctatgaagga aaagtgaaac tgattgctac tgggctcggt
     4381 gaagcaccta ctgcagtgaa caacgcttta cactatatta atccaaagga acgaactcag
     4441 cctggtcaca gcacaagctt atacgataaa aatcttcgtc ctagttgatt ttttatatct
     4501 ctttgcattt caagttaaac ccgaaagcag tttcttgcat ttttttcatg ttccgttaac
     4561 atgaaataga gaaagaaaaa ataaaggggg agcaataata tggtcgtcaa aactgagact
     4621 ttagaagaaa aggcaagaga actattgaag gaacgtggcg taactgtaga agatatcgca
     4681 caacttgtca tgtttttaca aaaagactat atttctgatt tgactttggc ggattgtact
     4741 gaaagtgtca acagcgtgct aacaaagcgt gaagtacata acgccattat cactggaatc
     4801 caattagata tattagcaga aaagaaaaaa ttgatgagtc cgttgcaaca tattatcgaa
     4861 gatgacgaag gcctttacgg tatcgatgag atcctagcct tgtcaatcgt gaatgtttac
     4921 ggtacgatcg gctttacgaa ttatggttat atcgacaagg tgaaacctgg tattttaaaa
     4981 gaactaaaca gccacgatgg cgttcatgtc cataccttct tagatgatat cgtcggagcg
     5041 atcgccgctg ctgctgccag tcgattagca cacaaagaac cagaaaaaag aagtcgcctt
     5101 actcaataat tcaacaaaaa aagaaagaaa acgtctattt agacgagttc tttctttttt
     5161 gtttgtttca agctattttt tcctaagaaa agaaaaacag caaaaaataa ttctaataat
     5221 acaaaaaata agataaagct atgcatgaaa aattcttctg gaagtacatt gatgattgga
     5281 tcagtaacgg gatcgaataa ccagtcatcg ttgttgaaaa acgtttcatg aaaaaggata
     5341 aaaaagcgat caaatcctat catcatgaaa aaaccgaaaa caactggcag taacatgccg
     5401 atttgaaacg gacgaatcaa ccgccaaagc cgatcattct tttgcaaata tttgataaac
     5461 aaaatactcg ggatcaaagt gatgaaaaac acagcataat ccactaaaaa caaaattttc
     5521 acttcataaa agtgatgggc tccgctagca gaaactggga aatctggcaa gctgaggatg
     5581 gttttgaagg gattattgag ataattcatt aggtgatcaa aatttttcag taacgtctct
     5641 tgatctaaag aagtataatc caaaatttgc aaatgtccga tatcaaatac gtatagtggt
     5701 cgaaagttga tcgtcacacc aactgccaga ctgatcagtg tcagaaatag gctgaacaat
     5761 ccagcatatt ccatccactg ccatctcgaa tttttcatat tagaagctcc attcatccag
     5821 tgattgtttc acataggtag ctgggatagg caacccaggt acatcttctt cttttgtaaa
     5881 acctgataaa acgagcaaag tatctatatt attgcgtatc ccagcttgga tatctgtttc
     5941 atagttatct ccaaccatga ttacttcttc tttttgcagc cctaatactt caacggcttt
     6001 atccataatg atggcttctg gttttccgat gtagatcggc ggcgtttggg ttgctgtctc
     6061 tacaaaagag atgactgacc ctgctccagg aagaaggccg cgttcagtag gtatattctt
     6121 atctgggttc gttccaatga aagtagcacc tttttgaata gcaagtgttg ctttaactac
     6181 tttttcatag gtcagataat tatctaagcc taccactaca tagtcaggag cctcttcttc
     6241 ccatgtaaat ccggcagcta aaatcaagtc aatcaatcct gcttctccga taacatagac
     6301 ttttttccct tttccatctg ctttcataaa atcgattgtt gccaaagtag ctgtgtagac
     6361 tgtctctgga gctacatgaa tgtcaaactc atctgctaga cgattagcta ctgtttctgg
     6421 tgacttagtc gtgttattgg taacaaacaa gaaaggtaat tttctttttt gcaattcttc
     6481 cacaaatcgt ttaccggccg gtatgggttg tgtcccacga taaatcgttc cgtctaaatc
     6541 aattaaatat cctttatagt ccattcatcc actactcttc cctttttctg atcgtaaatg
     6601 ctgtttttgt tttttctact tgtttaggtt gttcttgttt ttttactttt tcagaggttt
     6661 ttgctgactc tgtttttcga tttttaataa ccggtttttt gcgattagat gcgactggtc
     6721 cttttttctc atcgatatac gcacgattat ggtttttttt cttttttcgg cgctgagttg
     6781 tcttttcttt tttaccgccg attctctcga tgacaaaata cgcacaacca aaattgcaat
     6841 attcgtaaag atagtcttcc aaggaatcga ttcgctgatc tggatgcgcc cgtcgattat
     6901 ccgcttggaa aaatcctttt aggcgtagtt gttcataacc ccaatctcct acgatataat
     6961 catatcgggc tagtacatca ctgtaacgtt ctccaagctt ttctgcatta aatccttcac
     7021 gataatcgga cacaagccga taatgtcttt cacctatcaa aaaattactg tcatctaaca
     7081 gtgtcactag ctcgcctttg actttttctg ctttaggctc ctcaacgatt tcttccaaag
     7141 cagctgtcag ttcttcggtg actgttgttt cctgttcagc tgatgatttt ttcttagcaa
     7201 tttctgtttt atgctcaacg ttctgctgtt cattttgttt tgcagacatg cgttcaccac
     7261 ctatcttttt tattatacct tgtttttatt tgattgggta gtgagctttc aagtaatctc
     7321 ctaccacact tcggataaat tcagggaaca aaaattcatt ttttccagca atctcaatcg
     7381 ttggaaaaaa tggaacaaac atcaaatgat ctacggtagt aaaagtataa tttttattca
     7441 gatcgattgg cttgttcttc caaaagactt gatggttaat agaatcatat gtgattccat
     7501 tatagaccat ctgcccaaaa atcttaccgc gaaatcccat tcccttcata ggatagttac
     7561 gtaaaaagtt acgatttttt tctatttcta aaactaagcg gatcagatca tttccaccca
     7621 atgtgacatt taacaagtgc atcggatgcg gcaacgcagt gtgaagctga tcctgattga
     7681 cccgcccttt tggaatttca gttaaaaaca gaccactgtt taatattgct gcttccgtct
     7741 ttcctcgttc tttcaccgcc tcaaaggcta cttggataaa cgaatgctca ttgaagatat
     7801 ctagactcag agaaaatggc aaatctgcta cttctttttc ttttaataat tcatgcccac
     7861 gttctagata actatttatt tcttgttcat cttctgtaaa agctgtcatt gtttcggtag
     7921 ggatggcttt ggctgaatgc ttaaggattt ttttctcttc atcgatggtt aaatggactt
     7981 caccgacata ctgcccgtac tttccagcgg ctgctatttg gacatcattg attacgtgac
     8041 cttctctgaa taaatgatgg gtgtgcgatc ctaaaataac atcaattgct ggtatttctt
     8101 ttgcaatttg gaaatcatcc tgaatcccga gatgactcat caaaactaaa acatccactt
     8161 gtgaacgtaa atcttcgact aattctggca aaatatcata aggattccgt atgtcccagc
     8221 cattcggatt ataagtaagc ggaaatggag cagtaaatgc aattagtccg attttcgtct
     8281 ggtgtttcgt tgtaatgatt ttatatggtt tcgtccatgc cggtggctgg agcgtatttt
     8341 tatcgaataa gttatccagg atgatatcaa actcagcatg atcgtataaa tgattcaact
     8401 cttctttgga atttcctacg ccttcattgt ttcctatcgt cgctgcatca taaccaactt
     8461 cattcatcag caagatattt tcctgtccat tcgttgcttc tgacaatgga tgccaacgat
     8521 ccacaaaatc acctagatct actgcaatcg ttgtcgtttt ttctttcttt tcgttttctc
     8581 gtttacgttg atccaaaaac cttctgatcc ttggccaatt ttctaaatga gaatgcagat
     8641 cattcgtatg taaaatcact attttttcca tgtaccctct cgcctctctt tatctttatc
     8701 ataccatagg cagctttttc ttccattgaa acaagctcta tttcagagtt tttcctgcct
     8761 tgaagcaaat tgtataagta caatattcga taaatcagtc tggctaaaaa atcaggaaca
     8821 ttcattttta cagtactata aaaataaaaa aaacagaccc gaaagtctgt tgtcgtttca
     8881 ttataatcag acacatggcg gaacctgctt agtgctgctt ccttccagac ctgacacgct
     8941 tcacaagccc accattgtcc tagcctttcg gcaaagaata gtatacctta tttttcattc
     9001 gttgaccagt ctttttttaa tttctttttt cgctggcgga gctttcggaa aaagtcagtc
     9061 aaaatcatcc cacattcgtc ttctaaaatg ccaccttcta catatgcttg gtggttaaac
     9121 cgctcgtcct ccaaaagatt catcaaggta ccggctgttc cgccttttgg atcatacgcg
     9181 ccgaaataaa cttctgctac acgagacaaa atcatcgcgc cgctgcacat aggacaaggc
     9241 tctaaggtaa caaaaagtgc agcatcttcc aagcgccagc ttcccacttt ttcacaggct
     9301 tccttgattg caagcatttc tgcatgtgta gtagcatctt gcgtggtttc tctaaggtta
     9361 tatcctcttc caatcacttt tccatccaat acaaccactg ctccaatcgg aacttcatga
     9421 agcatttctg ctttctttgc ttctgccaat gcaaggcgca tccatttttc tttttctact
     9481 gcatcaagat ttgtatttac caattaccct tccctgcctt tgttttttct tgttttactt
     9541 tagcatatga taaaaaggct gtaactaact tttttttcta tggtaaaata aatacaagag
     9601 gtgaacaaga tgaaaatgga taaattactt gctctttacc cacaagcaca gaaaaaaaac
     9661 tctccagcat cagaagcgga tatcctttct tttgcaattg atgatgcttt tatctggatc
     9721 aaacaagatt cattatctca acaagaaacc agccttttga aagcgttatt ccctgtaatc
     9781 aacgatcaaa aaaaacaccc atggtatcgc tatcttttta aagatgcttc ttgtgttcaa
     9841 gaaaaaagct ttcgtttgat ccagcttcac gtcgaatcaa aaggagaatt cttaaaaaaa
     9901 gaatggcaag atactatttt ggaattattt cgctattctg ctgatttctt tttttataca
     9961 gacacagatg cgctcttagt cgaacaaata aaccgtgatt atcttgatgc tactgaaatc
    10021 aacggtattt ttctatcttt agatgctgat tttgatacga caacgtctgt attcgttggt
    10081 tctttccatt cacctggcac cgacctcgtc cctttgtttg ctgaagaaag aaaaattttt
    10141 ttaacagagc aaaacaatct ttatactcac agccgtactt tttctatgca agatgtggct
    10201 ttacattact atacaaaaga tactgtaaaa gatagtaagt tgatcaaaag ttacatagaa
    10261 ctgatcaaac aaaatgaaat ggaagtgatc attcaagaat tatggaatga attaggcaat
    10321 gtcagctctg ctgcaaaaac actgtttctt catcgtaata ctctaaaata tcgaatcgaa
    10381 aaatttcaag aacagtctgg tttcaatcta aaaaaagcca acgatttact gttttgctat
    10441 cttttattgc ttcatgaaca taattaaaga tagattaaag gggttgtgac aataattttg
    10501 tcacaacccc ttatttcgaa tgaatagtgt tcaaaagcta gtttctctta catcattttt
    10561 tcaacaaaat gcattagccg gtcttttaca tcttcggttg aatctttgat tgaatcacca
    10621 taaacagaga ttttcttttt tcctgatttg atttttgcta acattcccat caaagaatcc
    10681 aagtcactat ctgaaagacc atctacgatt tctagtaatt tttcatttcc atcaaatttg
    10741 tcatagacga atttttttac tttcgtccga gtagtcatat gatggatctt ttccattact
    10801 tttcccgata caacgactgc tgtcgctaca ctggcagcgg ctgctacgct taatccgatt
    10861 gttacttttg ttgatgtttt cataagtatc agctcctttt tatctatctc catcatagca
    10921 tagacaaaaa aataaacgaa ctaatccact cagtgaaatc tcaatccttt agggaaaaag
    10981 ttctttactg ttccttttac ttgtttccca aatccgacag gtatcttatc taatactagc
    11041 aaaacccatc cttgattccc atcacgttga aatgtttctc ctgctgtgta agattgccat
    11101 tccttttgag tgatcggcaa gcaaggtata ttctctatct tttttgtagc aagcgctaat
    11161 gcatagctag gttcaaatcg attctttttg aaatctccta aatgcaaacc tgtacgtacg
    11221 acttttaaac catcgagaga aggggctaac tcaggaactt cccaaagatg gtcgttgaac
    11281 actaaaagtc ttccagtagc ttcataatga aaatcatttg aaaactccgt ccagagtttt
    11341 tcctgctctt ttgtcatttg cactttactt ttttttcgtg tcttcttttc tttatgcatc
    11401 tgattttgtc catgaaaagt cagctttgca acaaaatgtc cttcaccctg atctttatga
    11461 ggccatatac gtattgtttt ttccaaacca gctacgcttc cccattcaga acgtcctgaa
    11521 ctaacggatt gagtcaaagg aatctcctca atcgttactg gataattttc tacaagccag
    11581 ctaatgatct cttcattttc ttctggtgca aacgtacaag tcgaataaat cagttgtcct
    11641 ttatttttta gcatttttat tgctgaagac aaaatctctt gctgacgttt ttgacagtat
    11701 agcggagatt cttctgtcca ctcttttatt gcatttggat cttttcggaa cattccttct
    11761 cctgaacaag gagcatcaac cacgatccga tcaaaaaagc ccgaaaaatg agggacaagt
    11821 tctgcgggtg catgatttgt cactattgcg ttcgaaactc cccatcgttc tatattttct
    11881 gataaaatct tcgcacgttt cggaaagatc tcattcgtca ctaataaccc tttccccttc
    11941 atttgagcag ctaattgggt tgatttacca ccgggagccg cacacaaatc caaaactttt
    12001 tcaccgggtt ttgctgcagc agctgttcca acgatcattg cacttggttc ttggctatat
    12061 tcatacccag cttgatggag gaaagacttt ccattgacag tgccaagaaa tccctcattg
    12121 ctgtagggag cgggttgtaa ttcttcgcta tggtaagttt ggaccatgtc caatcctgcc
    12181 ggttttagtg gattccaccg aaatcctttt ttcacgcttc cttgttcaag cgcagaaaaa
    12241 aaatcggatg cttcttcgcc taaaagaaga cgatattttt tgataaattg ctgtggtaac
    12301 gttgtcgctt cctccttcat tccaatgttt cgttagacat tttacaatct tttttacgaa
    12361 aaataaaggt ggctgatcta ctttttcatg ttgctgccta aggtgactgt tcctttaaga
    12421 tattttccaa gtattcatcc gtcacctcgt ttttatccca aacagcgttc atcatttcaa
    12481 gaaaatcttg agaagaatca tctgagcgca aacttcccaa tgcattaagc cataccaatt
    12541 caagcgactt ttcttctttg atcttcgtgt gacctttgac atatgagaaa aatggccgct
    12601 taaatagcga atccatgtct aaatcagatt ttgcaatgat ttcacgaata ctttcatgga
    12661 tagaaaaaaa atctttcaat aagtagacaa tgcttaaaac atcatcggaa ctgcattcag
    12721 ctaagtagtt ttcaaaataa acagtgattt cttctaatat cttctctttt aacccgctga
    12781 ttgatttgaa atgtgtataa atcgggtatg tagaacaacc gcagaactct gctaactctc
    12841 ttgcagtaat tgacttcatt ccatattctt ccacgtatac catacttttg aacagcaaat
    12901 attctttact ataatttgtt actctcccca tcattcttac ctccgtctct tttcatctac
    12961 ccataaataa ataacataaa taattctaaa aatattattg ataattatca aaacatattt
    13021 agttatatcc attaaaaatc aatttttccg ccttaaaaac aagaatatct tgacaaaata
    13081 ccctaggaaa taaacaatag aataaacaag gtaacaaaaa aattaaataa cgttatataa
    13141 aaaagaaggc gacactctgt gagaataaca cagactgaaa tgactttcca ctcacagttt
    13201 ttgtctaact atatacaaaa acagaataaa aaggaggtat ttatgctaat tgaagcaaga
    13261 aaaaaagagt tacttgttct acaaatggtc attcaaaaaa ataattgttc tttacaagaa
    13321 ttatccaatg acttacatat tccaaaacgg acaatcaaag aactgatccg aaaaataaat
    13381 gtatcactca agcaattttt attgattgat gaatttattt attctaatca taaaggagag
    13441 atccaaacca aagaaaccga tcaaactaaa aagttagctg ttttttctaa gttaaaatta
    13501 tgctacctaa aagaatccaa tcgttttaac tatttgatgt tactaatcaa ttatccacaa
    13561 actgctgtac caaaaaaata tttacttgaa caactttata tatcgccctc ctatctcgaa
    13621 aaactgacaa aacagctcaa tcattcctta aaaaaattcc atttacggat cctatctgta
    13681 aaaaattgct gtactcttga aggaaatgag ttatctatcc gtctctatct ttactttttt
    13741 ctttcagata catttggagg taacgattgg ccattttcct cacttgaatt aaatgcacta
    13801 aaaatgaaca gtacagatga gcaaatagaa aaaatttcaa aacaagaaaa aaatatctac
    13861 ttgctgttaa ctttattcat attacgaaac aaacaacagg catattttcc aaaaacttct
    13921 tctgaaatca ctgaattgat ggacttattg cagcatacac atgattattc agaatacttt
    13981 acttcttttt cagtgagtcg cccttgtgaa gagacagaaa cagagagagc ctactttaat
    14041 tattttttct attgtttttt tccaaatcaa atctcttttc gacaaaaaca ggagattggt
    14101 tttttatttt ccacaagcaa aaaccttatt tgtcgacaag tcggtcaatt gatgacttac
    14161 ttaactcaac agtttcctct caaccattta gaaaataaaa taccaattta tttttatttt
    14221 cttgtgttgg cagttgtttt tttcgaactg ttgggtgaat ccagcagtag tttttctaca
    14281 ctttgctttc cagaagccac gtccaatcat tctagttctt ttatacagga aaagaaatta
    14341 agagaaaaaa tcgatacaat tttttcaaaa aatggggaaa gaaaccaaat cagtcaatac
    14401 cttagtcaat tgatccaaca cttactacaa acagaaacga aagagcagtt actcatccat
    14461 ttgcagataa ccaaacagtt tacaggaaat tatcatcttc aaagccattt gcagcagtta
    14521 tttcgcaaag atgctgttaa aattaccgca tattcagaac atgctgattt gatcattaca
    14581 gatcagcatg agaaaatttc agatgaaacg gagactttct atctggatac aacgcacaat
    14641 acagtgttat ttggcaagtt aataaaagcg gttcatgaac tgtatatgaa aaaaggttat
    14701 gagaacaaaa caaagaggat gtgacaaaat tcttgtcaca tcctcttatt
//
LOCUS       DAFEKH010000066        14624 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.069, whole genome shotgun sequence.
ACCESSION   DAFEKH010000066
VERSION     DAFEKH010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14624
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.069"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            3..815
                     /locus_tag="LP386_002391"
     CDS             3..815
                     /locus_tag="LP386_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HBL1919600.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            812..1612
                     /locus_tag="LP386_002392"
     CDS             812..1612
                     /locus_tag="LP386_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HBL1919601.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            1773..3041
                     /gene="rseP"
                     /locus_tag="LP386_002393"
     CDS             1773..3041
                     /gene="rseP"
                     /locus_tag="LP386_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HBL1919602.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            3109..4818
                     /locus_tag="LP386_002394"
     CDS             3109..4818
                     /locus_tag="LP386_002394"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBL1919603.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            5030..9388
                     /locus_tag="LP386_002395"
     CDS             5030..9388
                     /locus_tag="LP386_002395"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HBL1919604.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            9533..10006
                     /gene="rimP"
                     /locus_tag="LP386_002396"
     CDS             9533..10006
                     /gene="rimP"
                     /locus_tag="LP386_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HBL1919605.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            10029..11204
                     /gene="nusA"
                     /locus_tag="LP386_002397"
     CDS             10029..11204
                     /gene="nusA"
                     /locus_tag="LP386_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HBL1919606.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            11226..11519
                     /locus_tag="LP386_002398"
     CDS             11226..11519
                     /locus_tag="LP386_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HBL1919607.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            11516..11827
                     /locus_tag="LP386_002399"
     CDS             11516..11827
                     /locus_tag="LP386_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HBL1919608.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            11840..14146
                     /gene="infB"
                     /locus_tag="LP386_002400"
     CDS             11840..14146
                     /gene="infB"
                     /locus_tag="LP386_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HBL1919609.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            14173..14520
                     /gene="rbfA"
                     /locus_tag="LP386_002401"
     CDS             14173..14520
                     /gene="rbfA"
                     /locus_tag="LP386_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HBL1919610.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
BASE COUNT         4982 a         2598 c         3255 g         3789 t
ORIGIN      
        1 gaatgttacg tttttttccg caaaaaaaca aatatattca agaaaaaagc gaatttcaat
       61 ttaataccga tggaccaatt cctcagcaca ttgccatcat catggacggc aatggtcgtt
      121 gggcgcaaaa ccgtcgtttg ccacgagttg ctggccataa agaaggcatg gaaacagtaa
      181 agaaagtcac aaaaaaagca tcaaggcttg gagtgaaagt gttgacgctt tatgcctttt
      241 cgactgaaaa ctggaagcga ccaaaagatg aagtaagttt tctcatgcaa ctacctgtcg
      301 acttctttga tacgttcgta ccagaattga ttaaagaaaa tgtcaaagtt catgtcatgg
      361 gttatgaaaa cgtattgcca gaacatacgc aagatgctgt aagacgtgca attgagcaaa
      421 caaaaaacaa tactggaatg gtattgaatt ttgctttgaa ttatggaagt agagcagaga
      481 tcgtgactgc tgtccaagaa attgccgaag aagtagcaaa aggagaaata cacgcagaag
      541 aaatcgatga tgaattgatt gctaagcatt taatgacagg tttcttgcct aaagagttac
      601 aagatcctga gctgatgatc cgtacaagtg gagaagagcg aattagtaat tttctgttat
      661 ggcagatcgc atatagtgag ctgtatttta caaaagcgct ttggcctgat tttgatggtg
      721 cgcatcttga agaagcaatc gcctcttatc aaaatcgaga ccgtcgattc ggcggtgtaa
      781 aaaaaacaga agatgagaaa ggggatcagt catgaaacaa cgtgtgatca cagcagctgt
      841 ggcgctagtc ttgtttattc cgattatatg gatcggaggc atagcggttg agcttacagc
      901 agcaatctta gcggtagtag gagtttacga gctgttccgg atgaaaggat tgacactctt
      961 aagttttgaa ggagttttat ccgccgttgg tgcagtgtta cttgttttgc caaaagaaag
     1021 atggtttttc tttcttccag agaatgtaag tacatttatg ttattttatc ttatagttat
     1081 gattctttta ggaacatcag ttatttctaa aaatacgtat acgattgatg aagcaggttt
     1141 tcctgtgctt gtcagcttgt atgtgggaat aggtttccag aattttgtca atgcacgaac
     1201 agaaagcttg gctgttttga tatttggtct atttattgtt tgggcaactg atatcggagc
     1261 atatatggtt ggtcgacgtt atggtcagca taagttaagt cctgatattt cgcccaacaa
     1321 aacgattgaa ggtgcgctcg gtggtatcgg tagtgctgtt gtagtcgcat ttctttattt
     1381 attgctatac ccagcaaaag aactattcaa tcatggtatg tttgtcatgc ttctgatgac
     1441 gattattttt tcagcagtcg gacaatttgg tgatttggtc gaatctgcaa tcaaacgtca
     1501 ttatgatgtg aaagactcgg gaaatatctt accaggccat ggtggaatct tagaccgttt
     1561 cgacagtttg ctgtttgtat ttcctatcat gcatttattt ggcattattt agtaagtata
     1621 cctgcgtttc tttgtgaatt tcataaaaga cgcaggtttt tatttttcat tatattgata
     1681 ctattggtgt ctttggtata ctatggtaaa attatagtgt tttatcgttg ttttataaaa
     1741 aacacaaaaa acaagtaaag gagaaaaaag ctatgaaaac gattctgaca tttatcatcg
     1801 tttttggtat attagtgatt gttcatgagt ttggtcattt cttctttgcg aaacgatcag
     1861 gaatcctcgt ccgcgaattt gctatcggta tgggtccgaa aatttatggg catcaagcaa
     1921 aagacgggac aacatatacg cttcgcctat tacctattgg cggttatgtt cgaatggcag
     1981 gcaatgggga tgatgaaaca gaaatggcac caggaatgcc tctttctctt ttactaaatt
     2041 ctgacggcat cgtagagaag ataaatttaa gtaagaaaat ccaattgaca aatgctatcc
     2101 cgatggaatt gagccgttat gatttagaag atgagctgac tatcactggt tatgtgaatg
     2161 gagacgaaac agaagtagta acctaccctg ttgatcacga tgcgacgatt attgaaaacg
     2221 acggaacaga aatcagaatt gcgccaaaag acgtacagtt ccaatcggct aaattgtggc
     2281 agcgtatgct gaccaacttt gctggaccca tgaataactt tattttggca atcgtgttat
     2341 tcatcattct ggcatttatg caaggtggtg ttcaagtgac gaacactaat cgcgtaggag
     2401 agatcatgcc taatggagct gcggcagaag caggcttaaa agaaaatgat gaggtagtca
     2461 gtgtggacgg aaaagaaatc cattcatgga atgatctgac aacagtcatt acgaaaaatc
     2521 caggtaaaac attagacttt aagatcgaac gagaaggtca ggtgcaatct gtcgacgtga
     2581 caccgaaatc tgtagagtca aatggcgaaa aagttggcca acttggtata aaagccccaa
     2641 tgaatacagg ttttatggat aagatcattg gagggacgcg tcaagctttc agcggttcat
     2701 tggaaatttt caaagcctta ggatcactat ttacaggttt cagtttagat aaattaggcg
     2761 gacctgtcat gatgtaccaa ttgtcttcag aagcagcaaa tcaaggtgta acaactgtta
     2821 ttagtttgat ggcgcttctt tcaatgaatc tcggaatcgt caatctgctt ccgattcctg
     2881 ccttagatgg cgggaaatta gtcttgaata tttttgaagg gattcgcggg aaaccattaa
     2941 gtcaagaaaa agaaggaata ttgacattag ctggctttgg atttttaatg ttgttgatgg
     3001 tgctagttac atggaacgat attcaacgat tctttttcta gaaaaagttg acaaataggg
     3061 tataataaca aacgataact attttgagga aataaaggag tatatagaat gagacaatca
     3121 aaaatgttga ttccaacatt acgcgaagtt ccaaatgatg cagaagtatt aagccatcaa
     3181 atcttgctaa gagctggata tatccgccaa gtatcagcgg gtatttattc atatctgcca
     3241 ttagcaaatc gtgtattgga aaaactgaaa cgcattatgc gggaagaatt tgaaaaaatc
     3301 ggagcggtag aaatgctgat gcctgccatc ttgccagcag aactttggga agaatccggg
     3361 cgttacgaaa catatggacc aaacttgtat cgtttcaaag accgcaatga tcgaaaaatg
     3421 atccttggac caactcacga agaaactttt actgatttga tgcgtaatga aatcaattca
     3481 tataagaaat tacctttaaa tctttatcaa atccaaccta aatatcgtga cgaaaaacga
     3541 cctcgcttcg gtttgcttcg cggaagagag tttatcatga aagatgcata ttctttccat
     3601 gcaacggaag aaagtttgga cgagacatat aaagattacg aaaaagccta taccgaagta
     3661 ttcaagcgtt gtggcttaga atttcgctcg atcatcggag acggcggcgc aatgggcggg
     3721 aaagactcaa aggaattcat ggcgatctca gaaatcgggg aggatacgat ctgttattcg
     3781 actgaaagtg attatgctgc aaacttggag atggctacaa gctactatgt atcaaaaaaa
     3841 tcgcatgaaa cacagcttga attggagaaa gtagctacac ctaacgtaaa atcaattgac
     3901 gaagtagcag atttcttttc tgttgaacct caaaaaatca tcaagtctgt attgttcatt
     3961 gcggatgaac aacctgtcct tgttttggta cgtggagacc atgaagtcaa tgacgtaaaa
     4021 ctgaaaaact ttttatctgc tgacttttta gaagaagcaa cagaagaaga agcacaaaaa
     4081 tatctaggtg ctgagtttgg ttctgtcgga ccagtcggtg tttcagatga cgtaaaagta
     4141 tatgcagacc gttatgtcca agatttagcg aatgccatta ctggagcgaa cgaaacagga
     4201 ttccactata aaaatgtgaa tccagaacgc gatttcactg tgctttctta tgaagatctt
     4261 cgttttgtac aagaaggaga tccttcacca gacaacaacg gtgttcttgc ctttactcga
     4321 ggaatcgaaa tcggacatat attcaaaatc ggcactcgtt acagtgaatc tatgggagca
     4381 actgtactag acgaaaatgg acgagaaaaa tttgtgatta tgggctgtta tggtatcggt
     4441 gtaagtcgtt tattatcagc aatcgtagaa caacattcag atgaacaagg aatcaattgg
     4501 ccaaaaggaa ttgcgccatt tgatctgcat atcgtccaaa tgaatctaaa agacgaatac
     4561 caaacaagcc tgacgaatga actagaagaa gcgatgacaa aagctggcta tgaagtactg
     4621 gttgatgaca gaaatgaacg cgcaggagtg aaattcgcgg attctgattt gattggctgt
     4681 ccaatcagaa tcactgtcgg taaaaaagca gtggatggaa tcgtagaagt gaaaatcaag
     4741 aaaactggcg aaatggttga agtacgtaaa gaagaattgg cgaatacttt accaatcctc
     4801 ttgaaccaag gcgaataata agcgttaaaa cacagaaaat aaaaatagct gaatcagctg
     4861 tttttgacaa tctgatgatt cgcttttaaa attggaactg cgatttgaat cgcagttcca
     4921 attttttaat gtaaaactca gaaaaaacga gtatactaaa aggtactgaa aaagaagagg
     4981 ataagatgcg atcaattgca ttgtttctca tcagaaaggg cgtatatctt tgtcagaaaa
     5041 acgagattta tttgaaaaac tgttggaaca aatccaacta gaggaagcag aaaaaaatca
     5101 tccactgctt actgctggtg aaatggatag tgtagtggtc catcgtaaat cgcgtttatg
     5161 ggaatttacg ctacattttt ccaaaatttt gcctattatg ctatatcggt cattgactca
     5221 gcatctgact atcgctttta aagatattgc acaagtcaaa ctgaatatct tagcagatga
     5281 ccagacattc gatgaacagc tcttgcaaga ttactgggcc caagctttgg aaaatcagca
     5341 atgcgataca ccactagcac agcaagtatt gaaaacgcag gtacctgtga taaaagatcg
     5401 taaagtcatc ttgccaatcg acagtacagg agctatttct tatttgaagc aacaatactt
     5461 gccattagta gaagagttgt tcgtcagtta cggattccca aaatttcgta tcgaaccaga
     5521 agtggatgag cagcaagcgg aacgagtatt gaaacttttt gaagaacgca aacaagaaca
     5581 ggcagaagcc tttatgaagc aagcagctga aagtctagtt gtccacgaac aaaagaaaaa
     5641 ggaaagaaaa gagcaatcgc cagctcttga aggacccatc cacatccagc taggacgaaa
     5701 tattccagcc gatgaaccaa cgacaccaat gatcagtatc gttgaagaag aacgaagagt
     5761 cacacttgag gggtacgtat tcgacaaaga agtcagagaa ctacgttcaa aacgcaagat
     5821 cttgactttg aaaatcacag attatacttc atcatttatc gtcaaaaaat tctcgaacgg
     5881 cgaaaaagat gaacaagtat ttgatgcgat cagtgtcggt agctggttaa aggtacgagg
     5941 aagtattcaa gaagatacgt ttgtccgtga tttggtcatg aatgcgcaag atatcataga
     6001 agtcaaacat acacctcgca aagattatgc tcctgaaggg gaaaaacgag tagagcttca
     6061 tgttcatagc aatatgagta cgatggatgc aacaaacagc atctctgatc ttgtggcaca
     6121 agcagggaaa tggggacacc gagctatcgc cattacagac cacggtggtg cgcaagcctt
     6181 tccggaagca catagtgctg gaaaaaaagc aggtgtgaaa atcttatacg gcgtggaagc
     6241 gaatgtcgta gatgatggtg tcccaattgc ttataatgat gcacatgaag cattgagtga
     6301 agccacatat gtcgtatttg acgtggaaac gacaggattg tctgcagtat atgacacgat
     6361 catcgagcta gccgcagtca aaatgtataa aggaaatgtg atcgaaagct ttgatgaatt
     6421 tatcgatcca ggacatcctt tgtcacgaac aacggtagat ctgactggta tcacggatgg
     6481 aatggttcga ggatcaaagt cggaagaaga agtattgcgg atgttccttg aattttcaaa
     6541 agatacaatt ttggtagccc acaacgcggc ttttgatatg gggttcttga atactagcta
     6601 cgcaaggtat ggtattcctg aagcggccaa tccagtcatt gatacgttgg aattagctag
     6661 atatctgtat cctcaattca aacgtttcgg attaggtgtg ttatctaaaa aatttggtgt
     6721 cagcttggaa cagcatcacc gagcaatcta tgatgctgaa gcaactggtc acttagcatg
     6781 gatctttgtg aaagaggcaa tggacaatca taacatgctt tatcatgatc agctaaatga
     6841 gcatatcgga gaaggagatt cttacaaaag ggctcgacct ttccatgtaa cgattttagc
     6901 aaaaaatcag gcaggactga aagatttgtt caaactgatt tcaatgtcga atgtcgaata
     6961 cttcgaacgc gtcccacgaa taccacgctc ccaattgaaa aagatgcgtg aaaatctatt
     7021 gatcggctca gcttgtgata agggagaaat attcgaagcc atgatgcaaa aaggggtaga
     7081 agaggcaaga aaccgagcaa aattctacga ttatattgaa gttatgccaa aagcggtcta
     7141 tgcgcctttg atcgagcaag aattggtaaa aaatgaacat gatttggaag aaattatcca
     7201 aaatttggta gaaatcggaa aaagtttgga taaaatcgtt gttgcaacag gtaatgtaca
     7261 ttatctgaac gaagaagatg ccatttaccg aaaaattttg atcaattcta tgggcggagc
     7321 gaatccgttg aatcgtcata gtttgccgga tgtccatttc cgaacaaccg atgagatgct
     7381 aactgcattt cactttttag gggaagaaac agcgaaagag atcgtagtag aaaatacgaa
     7441 taaaatcgca gatatctgcg aagaagtgat tccagtcaaa gatgaacttt atacaccgaa
     7501 gattccaggt tcagaagatg aaatatcaga attgagttac acaaaagcaa aacaaatgta
     7561 cggagatccg ttacctgaga tcattcaaaa acgattaaaa aaagagttga attctattaa
     7621 tggtaatggc ttctcggtta tttatctgat cgcccaaaaa ctagtgcata aaagtaatga
     7681 agatggctat ctagtaggtt cacgtggctc tgttggctct agctttgttg cgacgatgac
     7741 aggaatcact gaagttaatc cgttagcccc tcattattat tgtccagagt gccaatattc
     7801 cgagtttttt gaagatggta cgtatggttc tggatttgac atgccagaaa aacaatgtcc
     7861 aaaatgtggt gcacgcttaa acaaagacgg tcatgatatt ccatttgaga catttttagg
     7921 attccatgga gacaaagtgc ccgatattga tttgaacttc tcaggtgatt atcaagcaga
     7981 agcccataac tatacgaaag tattgtttgg cgaagactat gtttaccgtg ccggaacgat
     8041 tggtacagtc gccgacaaaa cagcatatgg ctatgtaaaa ggatacgaaa gggacaataa
     8101 tctgcagttt cgaagtgcag aagtcgacag attagcaaaa ggcgctactg gagtcaaacg
     8161 gacaaccggc cagcatccag gggggatcat cgttattccc gattatatgg atgtctatga
     8221 ttttacgccg atccaatatc cagcagacga tcaaaattcg gaatggaaaa cgactcattt
     8281 tgattttcac tcgattcacg ataatgtatt gaaattagat attctagggc atgatgaccc
     8341 aactgttatt cggatgcttc aagatttatc agggatcgat ccacaaacga tccctacgga
     8401 tgacccggaa gtgatgcgga tatttgccgg tcctgaagta cttggagtaa gtcaggaaca
     8461 aatttattcc aaaacaggga cattaggtat tccagaattc ggcactcgtt ttgttcgagg
     8521 gatgctagaa gaaacgcatc ctacaacttt tgcagaacta ctgcaaattt ccggactatc
     8581 tcatggtaca gacgtatggt taggaaatgc ggaagaattg attcgacgag gagatgcgac
     8641 actggcggaa gtaatcggct gtcgtgatga tattatggtt tatttgatcc atgctggatt
     8701 agatagcggg atggcattta aaatcatgga aactgttcgt aaaggacaat ggaacaagat
     8761 ccctgatgaa ttgcgagaaa cctatctatc ggcgatgaaa gaaaataatg tgcccgactg
     8821 gtatatcgat tcttgttcaa aaatcaaata tatgtttccg aaagcccatg ctgcagctta
     8881 cgtattgatg gctcttcgtg tcgcttattt caaggtttat ttccctattt tgtattactg
     8941 tgcatacttt tctgtacgtg cagacgactt tgatctagtc tccatgtgca aaggaaaaga
     9001 tgctgtgaaa caagcaatga aagaaatcac ggacaaagga ttagatgctt ccgtaaaaga
     9061 aaagaatcaa ctgacagtgc tggagttagc caatgaaatg ctggaacgag gattcaaatt
     9121 tggaatgatt gatttgtata aatcggatgc cgttaacttt gttattgaag gtgatacgtt
     9181 gatcgcacca tttagagctg tcccaagttt gggaaccaac gtggcaaaac aaatcgttga
     9241 agcaagaaaa gacggtccat ttttatccaa agaagatctt gccacccgcg gtaaagtttc
     9301 aaaaacattg atcgaatata tgaacgacaa tggcgtattg aaagatctac cagatgaaaa
     9361 tcaattatcg ttattcgata tgctataagc atctgttttc ctgtctgctt gtaattttaa
     9421 gcagagtatg gtatagttct tataggtaat gatactaact gtgagtgagc ggatttttcg
     9481 ctcactcttt ttaatggaat tacgcactta attttttaag gaggcgaaac ttttgagtag
     9541 cgtcgttgaa acagtcacag aaatggtgac accgatttta gatgaacaaa attttgaact
     9601 tgtcgaagtc gaatttgtaa aagaaggaaa aagctggttc ttacgagtat ttattgacaa
     9661 agaaggcggt atcgatatcg aagaatgcgc ctttgtcagt gagaaactga gtgaaaaact
     9721 tgatgcagca gatccagatc cgattcctca agcttatttc ctggaggtat cctccccggg
     9781 agcagagcgg ccattgaaaa aagaaagcga ctatgaaaag gcacttggtg attatgtcca
     9841 tgtctcctta taccaaccag tagatggcga aaaacaatat gaaggatttc ttcaatcatt
     9901 tgatgctgaa cagcttacat tgaaaatacg cataaaaaca cgagaaaaag aattgacttt
     9961 tgaccgaaaa aatattgcaa aagctcgctt agctatccaa ttttaatcac ggagaggaat
    10021 cagaaaaaat gagtaaagaa atgttaaatg cgttagacgc tttagaagct gaaaaaggga
    10081 tctcaaaaga aatcgtgatc gatgctttag aagcagcatt ggtttctgca tacaaacgtc
    10141 actatggcca agcacaaaac gtcgaagtgg aatttgatca gaaaaaagga aagatccatg
    10201 tctatgcggt aaaagaagta acggaagaag tgatggattc acagttggaa gtctcattga
    10261 aagatgcact tttaatcaat ccagcatatg agatcggtga tacgatccgt tttgaagtaa
    10321 caccaaaaga ttttgggcgg atcgctgcgc aaacggctaa acaagttatt ttacagcgtg
    10381 tacgtgaagc agaaagaacg attatttata acgaattcag tgcttatgaa aaagacatca
    10441 tgcaaggaat cgtcgaacgc caggataaac gttatattta tgtcaatctt ggtaaaattg
    10501 aggcagttct ttctaaacaa gatcaaatgc caaatgaatt ttatcaacca catgatcgaa
    10561 tcaaagttta tgtttcccga gtagaaaata cgtctaaagg tccgcaagta tttgttagcc
    10621 gcagccatcc agacctattg cgccgcttat ttgagcaaga agtaccagaa gtctatgatg
    10681 gaatcgttga aattgtcagc atcgcccgtg aagctggcga tcgttcaaaa gtggcagttc
    10741 gctcaaatga tccaaatatc gatgcagtcg gtacatgtgt cgggccaaag ggacaacgag
    10801 ttcaagcaat cgtcaatgaa ttaaaaggcg aaaacatgga tatcgtcgaa tggaatgaag
    10861 atccagctgt attcattgca aatgcattga atcctgcaca agtcatggat gtgatcttcg
    10921 atgagacaaa tccaaaggcc tgcacagttg tcgttccaga ctaccaatta tcgctagcaa
    10981 tcggtaaacg cggacaaaac gcacgtttag ctgctaaatt gactaaccat aaaatcgata
    11041 tcaaatcaga atctgacatg acggaatttt atgaaaatca agaacaacaa aaagaaacag
    11101 aagaactgca tgatgaagca atcgttcagt cagatttaac agacgatgaa tatgaaacaa
    11161 ttgcattcaa caatgaaacg gtcgaagaaa aaccagaagc ttaactttag taaggaggca
    11221 aagagatgaa acaaaggaaa attcctttac gcaaatccgt ggtttcaggt gaaatgaaac
    11281 ctaaaaaaga gatggtccga atcacccgtt caaaagaagg ggaagtatcg atcgatccaa
    11341 ctggaaaaat gcctggacga ggagcgtatg tctcacttga gccggaagaa gtacaacaag
    11401 cttgggataa aaaaattctc gatcgagtac tcgaaacaac attaacagat gagttttatc
    11461 aagaacttct tgactatgtc actcaccaaa aagcacgtaa agagttattt ggaaaatgaa
    11521 tacagttaat cggcaaaaag ccatgaatct catcggtcta gcgatgcgcg cgggaaaact
    11581 aatcacgggt gaagaactga ccattgctga aatccgcaaa caaaaagcaa aattggtgtt
    11641 tgtggcaacc gatgcaagcg agaatacaag aaaaaagata aaagataaga gttcatatta
    11701 tgaagttcct tgctttgagc tattttctga agcagaaatc acgcagatga tcggaaaacc
    11761 tcgcaaggta ttcggaataa tggatgccgg atttgcgaag aagaccaagg agctaattga
    11821 aggttaggaa ggtgattgca tgggcaacaa aagaatctat gaattagcaa aagaactcaa
    11881 aaaatctagt aaagacgtcg tggaaaaagc acaacaactt ggcatcgatg tgaaaaacca
    11941 tatgggtgcg attactagca atgatgagaa gaaattgcaa caagcgttca aaaacccaag
    12001 cacgaaacaa caagctgcac aacaagcaag cagaaaacca gccaatcaac agccgaacga
    12061 tcaacgtaaa aaagaaacaa cgaacaatca acaaaaaaat aaaaataacc gcagttatca
    12121 agatcgcggt caagggagcg gtcaagtgaa tcaaggaaaa aaaccaacaa caaaccaaaa
    12181 taatacggga aataccagca gccaaaatcg tcaaggaacg agccaaggcg gcaatcaaaa
    12241 ccgtactaac aataacaaca aaccaaacaa taacaatcgc ggcaaattta ataataataa
    12301 ccgtaatcgt tataataaaa aaggtaaaaa aggcaaacag caacaatcaa ctaaaccagc
    12361 tgtaccacca cgcaaattcc gtgaattgcc agatgtatta gagtatactg aaggtatgaa
    12421 cgtagcagat attgcgaaaa aaattcatcg tgagccagca gaaatcatta aaaaattatt
    12481 tatgcttggt gtcatggtca atcaaaacca agcactggat aaagatacga ttgaactgtt
    12541 agcgacggac tatggcatgg aaccacaaga aaaagtccaa gttgacattg ctgatatcga
    12601 taaattcttc gaggcagaag aagtcgatcc agataaatta gtctcacgtc cgccagtcgt
    12661 aacgattatg ggacacgtag accatgggaa aacaacttta ttggatacat tacgccattc
    12721 acgtgtaaca agcggcgaag ccggcggaat cacacagcat atcggtgcct accagatcga
    12781 tattgatggt aaaccaatca ctttcttgga tacaccagga catgcggcct ttacaagtat
    12841 gcgtgcacgt ggagcaagta tcacagatat cacgatctta gttgttgctg cagatgatgg
    12901 cgtcatgcca caaacagttg aagcaatcaa ccatgccaaa gctgcaggcg ttccaatcat
    12961 cgtcgctgta aataaaattg ataaaccagg tgcaaaccct caacatgtta tgcaagaatt
    13021 aagtgagtat gagttaattc ctgaagcatg gggtggagaa acgatctttg ttgagatctc
    13081 agcgaaattc ggccaaaaca tcgaagaatt gctggaaatg atcctgttag tcgcagaagt
    13141 agaagattta aaagcagatc caacacaacg cgcaatcgga acagtgatcg aagcacgtct
    13201 tgataaaggt aaaggtcctg tgtcaacctt acttgtccaa gaaggaacac ttcatgttgg
    13261 tgacccaatc gttgtcggta atacttacgg acgtgtccgt gtaatgacaa acgatcttgg
    13321 ccgtcgcgat aaagaagcag gacctgcaac gccagtagaa atcactggct tgaatgatgt
    13381 acctcaagca ggtgaccgtt tcgtagtctt cgaagacgaa aagacagcac gtgcagcggg
    13441 tgaagaacgc gcgaaacgtg cattattaga aaaccgtgct gccacaagcc gtgtgacttt
    13501 ggataactta tttgaaagcc tgaaagaagg cgaattgaaa gaagttaacg taatcatcaa
    13561 agcagatgta caaggttcag cagaagcact ggctgcatca ttgaagaaga ttgatgtgga
    13621 aggtgtccgt gtaaaaatcg tccattcagc tgtcggagca atcaatgaaa gtgatgtaac
    13681 cttagcagca gccagcaacg ctattatcat cggtttcaac gttcgtccta caccgcaggc
    13741 aaaagtgcaa gctgatactg aagaagtcga tattcgtctt caccgtatca tctataaagc
    13801 catcgaagaa atcgaaactg cgatgaaagg gatgctagac cctgaatttg aagaaaaaat
    13861 caccggtcaa atgatcgttc gtgaaacctt caaagtttct aaagttggta cgattgcagg
    13921 tgcctatgta acagaaggat atattcgtag agatagcggt gtccgtgtaa tccgtgacgg
    13981 aatcgtaatc tatgaaggcc aacttgcaag tctgaaacga ttcaaagatg acgtgaaaga
    14041 agtcaaaatg ggttatgaat gtggtgcaat gattgaaaaa ttcaatgaca tcaaagtaga
    14101 tgacgtaatt gaaggattta tcatggaaga agtcaaaaat gactaaaaac tgataaaagg
    14161 aggccaatca ttatggctaa ctaccgtgac cgccgagtcg gtcaagaaat cttaaaagaa
    14221 gtcaatgata ttttgcgcaa aaaggtccgt gaccctcgtg tggagaacgt aacgatcaca
    14281 gatgtgaaag ttacggggga cttacagcaa gcaacgatct attacagcat tttatctgac
    14341 ttagcatcag ataagaaaac agcacaagat ggattgaata aagcatcagg attgattcgt
    14401 cgagagttag ggcacaatct aagtatttat aagacacctg aattgttctt tgaacttgat
    14461 gaatcagttg tctatggcaa ccatatcgat gaattgcttc gcgacttgaa caaagactaa
    14521 tcaaaaactc ccgcaaatcc tgtgaaatca ggctctttgt caataaggac tgatgagttg
    14581 tgcaaaatca aatctgagtc agaatgaacc acattctggc tcag
//
LOCUS       DAFEKH010000067        14511 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.070, whole genome shotgun sequence.
ACCESSION   DAFEKH010000067
VERSION     DAFEKH010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14511
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.070"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..153
                     /locus_tag="LP386_002402"
     CDS             <1..153
                     /locus_tag="LP386_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBL1919611.1"
                     /translation="NKFYQSLRTASSTIKGMETIRGIYKKNRRNGTLFSFSVSTEIKV
                     LMGITA"
     gene            159..575
                     /locus_tag="LP386_002403"
     CDS             159..575
                     /locus_tag="LP386_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919612.1"
                     /translation="MEFREGAFDFQTSQQNRKFIPEDFQNLQLENMRLEDLFRLADDD
                     KYRFEVLKIKKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNR
                     NSTDVVMITDIYVEDEVIIKYMKPVIKLVNKNKGNG"
     gene            681..944
                     /locus_tag="LP386_002404"
     CDS             681..944
                     /locus_tag="LP386_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBL1919613.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDLKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            944..1216
                     /locus_tag="LP386_002405"
     CDS             944..1216
                     /locus_tag="LP386_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBL1919614.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTYEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            1293..1622
                     /locus_tag="LP386_002406"
     CDS             1293..1622
                     /locus_tag="LP386_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL1919615.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            1612..1899
                     /locus_tag="LP386_002407"
     CDS             1612..1899
                     /locus_tag="LP386_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBL1919616.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKVIPVLLCGTHENFYEQLKKLI"
     gene            2185..3042
                     /locus_tag="LP386_002408"
     CDS             2185..3042
                     /locus_tag="LP386_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBL1919617.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            3043..3591
                     /locus_tag="LP386_002409"
     CDS             3043..3591
                     /locus_tag="LP386_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919618.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            complement(3888..4835)
                     /locus_tag="LP386_002410"
     CDS             complement(3888..4835)
                     /locus_tag="LP386_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator"
                     /protein_id="HBL1919619.1"
                     /translation="MHLEFSDYESLLVKICEDYYLEDINISEISKKYGITRYKALKYI
                     EDAREKQLVSISINSPYARNYELEEIFKNYFKTNIYILKSSEDLSQHDLLFSKFAADY
                     IQELIKKANVVALSWGDTVYKVIDQFKMGAREELIFTQFIGEIGKYNSLAGSTRLVQK
                     AAERYESSYLTLSIPLYVINETARELMALEPSLANTLATASHADMLISGIGTLSSIDS
                     VEPWNKHRKILFPSMTDTVGFLYGRPFNINGEFIKASEDKTFGLSLKEIFDIPKRIGI
                     CKSKFKAESCLGALNGNFFTDLFLDEKTAWKILSLIKKE"
     gene            5023..6210
                     /locus_tag="LP386_002411"
     CDS             5023..6210
                     /locus_tag="LP386_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HBL1919620.1"
                     /translation="MLDEVLEIHKKNVGVLRMETTEAVQDDQDLAKMYTPGVAELSLM
                     IEKNHALARELTISGKLVAVITDGSAVLGLGNVGNQAGLPIVEGKALLYKNLAGVNAI
                     PLAIEQKSVDEIVQTIVNLQNSFAGIHLEDIAAPKCFEIEEKLQEKLSIPVYHDDQEG
                     TAIVVLAGLINAAKIQRKTLTELRVLINGMGASGVATARLLIAAGIKNLTLVDKQGRL
                     KKQDSTLNKYQRELLDHIHDTNNNASVLEDAIVGQDVFIGLSIGNVLTPEMIGKMNDN
                     PIIFALANPVPEITPDLAKESGAKLIATGSSKYPNQVNNILVFPGLFKGLLLSKANKV
                     DLSLQLEVAKQLAAKVAEPTVEKFIPNVFDEGVANVVSQAVLDYLQKLKENEDNIHAE
                     NIK"
     gene            6191..7495
                     /locus_tag="LP386_002412"
     CDS             6191..7495
                     /locus_tag="LP386_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HBL1919621.1"
                     /translation="MLKTLNRIKIGFIPLSLYIILVLAYLAMTISNIVPENDMLVSLG
                     IMTVFAYLLEEIGKTIPILKDLGGKVLVVTFLPAFLVYKHWLPQSTVTVVSDFMNNNN
                     FLMFFITLLVVGSIASMNRQTLVKATSRIIIILILCDVIGSLIGTGVGILLGLSAWNA
                     YFFIVAPIMAGGVGEGAMPLSIGYAAILSGMGQNDIFGKILPCVMLGSLVAVLLSGML
                     KKIGEKYPQLNGQGNLIDGDDEHLENLKGSAKPVNIEKTLLAGVVAITIYFVAVYVEH
                     LLKSLLGFSIPSPVILLVSLMGAKMLGFIPKNIEEGGNSLYGFTVRGITPPLLFGVGV
                     AKTDWLELIEVFKNPATIVTIIVTVVAIVATAFIAAKFLKMYPVDTAIAVSCCSGQGG
                     TGALAILAAGDRMELMPFAQVAVRLGGAMTVTFAIFLMGLLS"
     gene            7521..8534
                     /gene="citC"
                     /locus_tag="LP386_002413"
     CDS             7521..8534
                     /gene="citC"
                     /locus_tag="LP386_002413"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HBL1919622.1"
                     /translation="MFDQTDIQRLFLKNNYIKDQWENLLLDSGIQKKQIEDFQHLDQT
                     LGIYHKEKLVGTVSYQNNVIKYIAVSEKYKDGGHTFNVLVSAIIQAMSQQEIFHYIVF
                     TKPRYQKSFNFLGFETIVSTPKIAVLEMGDSSIKQYLERIPKVNGEKKAAIVMNANPF
                     TEGHYYLVKQAANNNDWVYVFVLEKEQNLFSTKDRLKLVQQGLQKLKNVIVLSGGEYI
                     ISPATFPTYFLREDDEIAKEQMVVDATLFKERIATYLDISARYVGEEPLSPMTRSYND
                     ILETILPPEIKVHVLARKKTEQHQVISASQVRKAYLAGQLEKIKYMVPETTYQYLKNK
                     RER"
     gene            8538..8831
                     /gene="citD"
                     /locus_tag="LP386_002414"
     CDS             8538..8831
                     /gene="citD"
                     /locus_tag="LP386_002414"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HBL1919623.1"
                     /translation="MEINKSAIAGTLESSDVQIMISPNTEGIEIDLDSQVIEQFGKQI
                     KKVIYDTLAVYQIKNVKLKVVDKGALDCVIVARLKTAIHRSLGIQHQETPWEV"
     gene            8836..9741
                     /gene="citE"
                     /locus_tag="LP386_002415"
     CDS             8836..9741
                     /gene="citE"
                     /locus_tag="LP386_002415"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HBL1919624.1"
                     /translation="MMKERLRRTMMFVPGNNPAMIKDAGIYGADSIMFDLEDAVSMAE
                     KDSARMLVAEALKTVDYGDTELIVRINDLHSEFGRADIFAMVKAGAHVLRLPKTETSE
                     DITEVEKVIIEAENYHNVPIGRTLMMAAIEGASGVLNAPAIAKASDRLIGIAIGAEDY
                     VTNMKTKRYPDGNELFFARSMIVHAARAAGISAFDTVYSDVDDMEGFLNEVRLIHQLG
                     FDGKSCINPRQIPVVNTVYQPSIKEIKRSLDIISAIEEAKEKGSGVISLNGKMIDKPI
                     VERAQRTLMLAKASRLIDEEGNIHA"
     gene            9734..11293
                     /gene="citF"
                     /locus_tag="LP386_002416"
     CDS             9734..11293
                     /gene="citF"
                     /locus_tag="LP386_002416"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HBL1919625.1"
                     /translation="MHNKQRRSIPSSVLTKYKKEFQSVSLSPQTIQRCAPKVTTVTNQ
                     TNKLMHSIKEAIEKSGLKDGMTISFHHHLREGDFVFNQVMAVIREMGIKELTLAPSSL
                     TNTMNEMVIECIKDGTVTHITSSGMRGSLGEFISHGGMDNPVILRSHGNRPRAIESGE
                     LKIDVAFLGVPTSDDYGNANATVGKSVFGSLGYAKVDAQYADKVILLTDHLVPYPNTP
                     ISIPQTQVDYVVEVEAIGDPNKIGAGATRFTKNPKELKIAEMVKDVIVHSPYFKDGFS
                     FQTGTGGAALAVTRYLASEMEEKQIKASFALGGITKPTVDLLEKGLVEKVLDVQDFDK
                     GAAEGMARLENQQEIDASFYADPSNKGAVVNQLDVAILSALEIDTNFNVNVMTGSDGV
                     LRGAIGGHQDAATAKLTIISAPLVRGRIPTVVNDVTTLITPGKSIDVLVTEVGVAINP
                     QRKDLIAIFERIPQIPVFTIEELQQKAEKIVGIPEPLQFTDRIVAYVEYRDGSILDVV
                     RQVKEFEEERS"
     gene            11290..11847
                     /gene="citX"
                     /locus_tag="LP386_002417"
     CDS             11290..11847
                     /gene="citX"
                     /locus_tag="LP386_002417"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HBL1919626.1"
                     /translation="MMFDTGEIQEIEDILIHKEQRANLQSNLLSKYSNSSLMVFTLNI
                     PGPIKNNPMIEQVFRQGQQSIQQMFLKKKVEMTYTKEINLPSGLDWYVIVTEAPLNLK
                     KWLVTLEEQDALGRLFDLDVLFKKGEQITIVSRQALNHGERPCFICGKSAKVCARNRT
                     HTVKEMQKKIEQIVADSLKGALKHA"
     gene            11840..12703
                     /gene="citG"
                     /locus_tag="LP386_002418"
     CDS             11840..12703
                     /gene="citG"
                     /locus_tag="LP386_002418"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HBL1919627.1"
                     /translation="MHDNIQKIAQEAQLAMLYEVTCINKPGLVDPVDPGSHQDMDIFT
                     FLQSSVVLTPYFEEFIQTGLDRQHQPIEETFMAIRQIGLEAETAMFSVTNGINTHKGA
                     IFSLGIFLAICGRLTIWKVPCKKSFFQKEIQKMTKNLLNDFGKIDQTKPKAWTWGEYL
                     FVNHGLTGIRGEAKRGYPCVFDRGLPYYQAYQGSQQDKMIDTLLFLSMEVEDTNLIKR
                     SNNRHVFEEYQLLIRPYFELGGVKTIQGKKYLDYLNQQFKKKNWSIGGSADLLILTIF
                     LDKIMDKGWLC"
     gene            12937..13346
                     /gene="tnpA"
                     /locus_tag="LP386_002419"
                     /pseudo
     CDS             12937..13346
                     /gene="tnpA"
                     /locus_tag="LP386_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(13983..14511)
                     /locus_tag="LP386_002420"
                     /pseudo
     CDS             complement(13983..14511)
                     /locus_tag="LP386_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5156 a         2168 c         2859 g         4328 t
ORIGIN      
        1 aataaatttt atcaaagtct ccgtacagcc tcttccacga ttaagggcat ggagaccatt
       61 cgaggaatat ataaaaagaa ccgaagaaat ggaacgctct tcagcttttc ggtgtctact
      121 gaaatcaagg tattaatggg aataacagcc taagatattt ggagttcaga gagggcgcgt
      181 ttgattttca aacttcgcaa cagaaccgaa aatttatacc ggaagatttt caaaacttac
      241 agttagaaaa catgcgttta gaagatttat ttagattagc agatgatgat aagtatagat
      301 ttgaagtttt gaaaattaaa aagaatgaac tattgaataa gttatatcct gagaatgcga
      361 taaaagcaca ttttggtgat gctaatcata tgtatagttg gttcattcct aaaagattta
      421 gagggaaaat caatgctgga gatcaagtga aagtactcaa tcgaaatagt acagatgtcg
      481 taatgataac agatatctac gtagaagatg aagttataat caaatatatg aagcctgtga
      541 taaaacttgt taataaaaat aaaggaaacg gataacactt tacaatgctg ttttggtact
      601 ccaatttaaa caaaacaatc gaatttacgt acttaattaa gtacgttaga atggagatat
      661 aaattagagg gggagtagat atggcaaaaa cagtcttaaa tcctagctca gcacggaaaa
      721 atttttataa gttgttgaaa gatgtaaatg agaatcatac ggaaattgaa atcattagtg
      781 agcgcagtga aaataatgcg gtgcttattg gtttggatga tttgaaagca atcaaagaaa
      841 cgctattact tgagcaaata ggcactttgg gtgttgttcg taagcgagaa aaagatgata
      901 gtggatttac taatgttgat gaaattgatt gggataactt ataatgaata actattctgt
      961 gatgattaaa aactcggcta aagctgattt aaagaaaatc aaacagtcta atttgaaacc
     1021 tcaatttgag aaggttattc agactttaaa ggaagatccc tatctcccta cccaatcatt
     1081 tgagaagtta aaacctacat atgaaggtag gtattctaga agattgaata gacaacaccg
     1141 ggttgtttat aaggtagatg aagatgaaca cgtggttgaa atttattcag caaggacgca
     1201 ttacgagtca cagtaattac ttgtaaatac attatctcgt ggtataatgt atttactaag
     1261 taattacata ctgttagaaa tgagggattt aaatgattac aaaaacaaga aaacaaggca
     1321 attcaatcat gttgacagta cctaaagatt ttaatgttcc taatggagtc gaagttgaag
     1381 caaagttggt agagaatggt attctttatg aatttgttga accacaaaaa gaattttatg
     1441 attttagcga agatattttg tctgatataa ttgcagaagg ctacgataaa gatgagattc
     1501 ttgtagaatt taagaataga aaaaacaaaa tgcattcttc ctttagagat attgctgaag
     1561 atacacttac taattctaaa gtaatgacta aagaggagtt ggcaacagaa attggcttat
     1621 gaaatcgttc cttcaaaaca tgtcattaag tatttaaaaa agctaaaaga gaagccattg
     1681 aaagaaaaat ttttgaattt aatttatgat gaaattgcga ttgatccata taagggtgaa
     1741 caaaaaactg gggatttatc aggtatttgg tctagtgggt tcaaatatgc gggcacaaca
     1801 tatagagtag cttacgagat tatagaaaac aaggttattc cagtattgtt atgtggaacg
     1861 catgaaaact tttatgaaca gttgaaaaaa ttaatctagt gatttgttgt cgttcttaag
     1921 aaggacggct tcttttttat cgaaaatctg attcgtctac atgactaaag tcgcgagtat
     1981 tctctgcttc tcgataaatt aaataacgtc attactttga ggaaagctat aaatcaatat
     2041 atttcaactt ttccttattt atgtactacc ttttacttat taattataag gtagtacata
     2101 tatatctttt ttttggtagt aactaaaaat aaatatgtta taatagtatc aaatgaatat
     2161 tgctaaaaga aaagaggtag gaacgtggta gcgaagaaat atgtaattgg taattttaaa
     2221 ggtggcgtag gtaaaagtac gtgcgcgcaa atgttagggt ttgaatcagc agttaatgaa
     2281 ggaaaaagaa ccttgataat tgacttggat atgcaaggaa atacttctga tgtgatgaac
     2341 ttaacgcata tgaacttcac taacgaagaa ggaggcggag aaggtgaacc gattgtttac
     2401 gaaaatactg tgactgacgt gttgataaac aatcttccac ctaaagaggc tgtctataaa
     2461 gtaatcaata acctctatat acttccagca gatatgtcct ttgaaatgta tgatgattgg
     2521 atcaaagacc aatataatga ttcattatcc caattcaaat atatgaaaga aaagctagaa
     2581 ccattatttg atgagtttga cgtcatctat ttagatgtcc caccttctat ttctgtatat
     2641 agtaaatccg cgatgtacat tgcggactgg gcaatcgtcg tcttacagac ccaagtaaaa
     2701 tcgatgagaa atgcgatgca atatcttgag tatatggact tttttgtgaa agaatttgat
     2761 acaaatttat atgttgctgg tgttattcct ttcatgttgg aaagcggtga cgcagtagat
     2821 caggaaatgt ataaacaagc ccaagagatt tatggggaac atttgattaa aaatgttgta
     2881 ctcaaaaatg cgcgcttaaa acgatacgac ggatcaggta ttacgatgga gaagacaaag
     2941 aaaggtctct taaaacaatg ggatcgcaaa agccacgaat tatttatcag tattttgaaa
     3001 gaattggaag aacacgagaa ttggtatgcg gaggtggagt aattggctga catcaaagga
     3061 cttgatattt ttgggaacaa caaaggactc gccaaaataa aaaaagaagc agaagcaaag
     3121 aaaaagcagc aagcaattac accatctgaa aataagcaat tagaagtgca ccaagttcaa
     3181 gaaataaaaa cttcctccaa tgttgaaaga cagagtagag gaagaacaaa aaaagttggc
     3241 gcaccaatca gaaagtttga taaggtttat tccaccaagc atcctttaaa actgtcgact
     3301 ttgttaaatg cgacttccag agttttagta gaaaagtatg agactaatat gacaagagat
     3361 gaattgctta gaaaagcttt agatgagtat attaaacaga atcttacgca agaagataag
     3421 caagatttgt ttaatgacgt ggtgaaagaa ctagacttgt tcagagaaaa atatccaatt
     3481 gttccagaat tagatgaccg tggagaaata ataagaacta ccagtcagat aaaacaagat
     3541 accgaagact cactgcgcaa agggtgggga atgaataata aagttagata gaaccccctt
     3601 tttatagcat aaaaaagatt tagaaggata tatgatccta ttgcatgaga agtacaataa
     3661 aattaataag aagtaacatt aacgaaaaaa cgtggaaatt attcagtgaa tacaaagaaa
     3721 ttaaatcttg aaaagtaatg gagtatggct tggaaaagtt caaaaaatat caagacaagc
     3781 ttctcaaaaa aagggatttt gatatccaat aaaaagagtg aatcattgta ctgccctcca
     3841 aaaaagtagt accaaaaatc taaatttttt ggaggatttt acatgactca ctcttttttt
     3901 atcaaagaaa gtattttcca agcagttttt tcatccaaaa ataaatctgt aaaaaaatta
     3961 ccattcaagg cgcctaaaca actctccgct ttgaacttac ttttacaaat accaattcgt
     4021 tttggaatat cgaaaatttc ttttaaagaa agaccaaaag tcttatcctc agatgctttg
     4081 atgaattcac cattgatatt gaagggtctt ccgtaaagaa atccaacagt atccgtcatg
     4141 cttggaaata ggattttacg atgcttgttc cagggttcga cagaatcaat agaggataag
     4201 gtgccaattc cagaaattaa catatctgca tgcgaagcgg ttgctaaggt attagctaaa
     4261 gaaggttcta gagccattag ttcacgtgca gtttcattga tgacatataa aggaatactg
     4321 agagtcaaat aagaagactc ataacgttca gcagcttttt gaactaatcg tgtggagcca
     4381 gctaaggaat tatattttcc gatttcgcca atgaattgag taaaaattaa ttcttcacga
     4441 gcacccattt taaactgatc aatcactttg taaacggtat ctccccaaga tagtgcaacc
     4501 acattggctt tcttaattaa ttcttgaatg taatcggcag caaattttga aaataataaa
     4561 tcgtgttgtg ataagtcttc actacttttt aatatataga tattcgtttt aaagtaattt
     4621 ttgaagattt cttctagctc ataattccta gcatacggag aattaattga aatactaact
     4681 aattgttttt cacgtgcatc ttcaatatat tttaaagctt tatatctggt gatcccatat
     4741 tttttagaaa tttcactaat attgatatcc tcgagataat agtcttcaca aatttttaca
     4801 aggagtgatt catagtcaga gaattccaga tgcatagtat agctcctaac tttttcaaat
     4861 agatattttt tctcattata ccaaaaaaat tgaatttagt ctttttttaa atttttaaaa
     4921 ataagcatca tttttttaaa atttaaaatg aaagggtttt tttattttaa aaaaagtgtt
     4981 aaagtggttt tgtaattaaa aaatgtaaaa aggagtgaag gtatgcttga tgaagtttta
     5041 gaaatccata aaaaaaatgt aggtgtttta cggatggaaa caacagaagc cgtgcaagat
     5101 gatcaagatt tagcaaaaat gtacacccca ggtgtagcag aactaagttt aatgattgag
     5161 aaaaatcatg ctttggcaag agaattaaca attagtggta aattagtggc cgttattaca
     5221 gacgggtcgg cggtattagg tcttggaaat gtaggaaacc aagctggatt accaatcgtc
     5281 gaagggaaag cgctgcttta taaaaattta gcaggtgtca atgcgattcc attagccatc
     5341 gaacaaaaat cagtagacga gattgtacaa acaattgtca atttgcaaaa tagttttgca
     5401 gggatccatt tagaagatat tgcagcaccg aagtgttttg agattgaaga aaaattacaa
     5461 gaaaaacttt ctattcctgt gtatcatgac gatcaagaag gaacagcgat agttgtttta
     5521 gctggattga tcaatgctgc taagatccaa aggaaaacat taactgaact tcgagttttg
     5581 atcaacggca tgggagcatc tggggttgca acagctagac tattaatcgc tgctggtatc
     5641 aaaaatctaa cattggtgga taaacaaggg agattaaaga agcaagatag tacattaaat
     5701 aaatatcaaa gagagttgtt ggatcatata catgatacaa ataataatgc aagcgttttg
     5761 gaagatgcaa tcgttggaca agatgttttt atcggtcttt caataggaaa tgttttaacg
     5821 cctgaaatga ttggaaaaat gaatgataat ccgattattt ttgctttagc caatccagta
     5881 ccagagatca cacccgattt agcaaaagaa tctggtgcaa agctaatcgc tacaggttct
     5941 tcgaaatatc ctaaccaagt aaacaatatt ttagtatttc ccggattgtt caagggacta
     6001 ttactatcga aagcgaataa agtcgatctt tcattacaac ttgaagtagc caaacaatta
     6061 gctgctaagg tcgcagagcc tacggtagaa aaattcatcc ctaatgtttt tgatgaagga
     6121 gtcgcaaacg tcgtttcaca ggcagttttg gattatttac aaaaactaaa agaaaacgag
     6181 gataatatac atgctgaaaa cattaaatag aattaaaatt ggttttattc ctttatctct
     6241 ttatatcatt ttggtactcg cgtatcttgc aatgacgata agcaatatcg ttccagaaaa
     6301 tgatatgtta gtttctttgg gtattatgac tgtttttgct tatttattag aagaaattgg
     6361 taaaactatt cctattttaa aagatttagg tggtaaagta ttagttgtta catttttgcc
     6421 tgcatttcta gtctataaac attggctacc tcaaagtact gtaactgtgg tttctgattt
     6481 tatgaataat aacaatttct tgatgttctt tatcacacta ctagttgtcg gcagtattgc
     6541 ttcaatgaat cggcaaacat tggttaaagc aacttcacgt attatcatta ttttaatttt
     6601 atgcgatgtg attggttctt tgataggaac aggtgtggga atactccttg ggctatctgc
     6661 ttggaatgcg tatttcttta tcgttgcgcc gattatggct ggtggtgttg gggaaggagc
     6721 gatgccatta tcgattggtt atgcagcaat attatctggt atgggacaaa atgatatctt
     6781 tgggaagatt ctaccgtgtg tgatgttggg aagtttagtc gcagttctac tgtctggtat
     6841 gctcaaaaaa attggagaga aatacccaca attaaatggt cagggtaatt tgatcgatgg
     6901 ggatgatgaa catttagaga acttgaaggg ttcagctaaa ccagtcaata ttgaaaaaac
     6961 attgttagca ggcgtggtag caataacgat ttattttgtt gctgtctatg ttgagcactt
     7021 attaaaatca ctccttggct tttctattcc ttcacctgtg atcttattag tctctcttat
     7081 gggggctaaa atgcttggtt ttatccctaa aaatatcgaa gaaggtggaa attcgttgta
     7141 tggattcact gttcgtggga tcacacctcc cttacttttt ggcgtagggg ttgcaaaaac
     7201 agattggtta gagctgatcg aagtatttaa aaatcctgca acgatagtaa caatcattgt
     7261 gacggtagta gctattgtcg ctacagcttt tatcgccgca aaatttttaa aaatgtaccc
     7321 agttgatact gccatcgcag tttcatgttg tagcggacaa ggcggtacag gtgctttagc
     7381 tatcttagct gcgggtgatc gcatggaatt aatgccattt gcacaagttg ctgttcgact
     7441 agggggtgct atgaccgtaa cgttcgctat ctttttaatg ggtctgctat cataagaaca
     7501 taaagaaagg acgtgaccat gtgtttgatc aaacagatat ccaacgatta tttttaaaaa
     7561 ataactatat caaagaccaa tgggaaaatc ttttgcttga ttcaggaata caaaagaagc
     7621 aaatcgaaga ttttcaacat ttagatcaaa cattgggtat ataccataaa gaaaagttag
     7681 taggaacagt atcttatcaa aacaacgtga ttaaatatat cgccgtgtct gaaaaatata
     7741 aagatggtgg acatacattt aatgtactag tctctgcaat aattcaggca atgagtcaac
     7801 aagagatttt tcattatatt gttttcacga aaccgcgcta tcaaaaaagt tttaactttt
     7861 taggttttga aacaatcgta tctaccccaa aaatagctgt attagaaatg ggagatagtt
     7921 ctataaaaca gtacctagag aggattccta aagtgaatgg tgaaaaaaaa gcagcaattg
     7981 tcatgaatgc gaacccattt acagaagggc attattattt agtaaaacaa gctgccaata
     8041 acaacgattg ggtatatgta tttgtactcg aaaaagaaca aaatcttttt tcgacgaagg
     8101 accgactcaa attagttcaa caaggattac aaaaactgaa aaatgtcatt gttctatcag
     8161 gtggcgagta tattattagc cctgcaacgt ttcccaccta ttttttacga gaagatgatg
     8221 aaatagcaaa ggagcaaatg gtcgtagatg ctactttatt caaagaaaga attgccactt
     8281 atttagatat ctctgctaga tatgtgggag aagaaccact ttccccaatg actcgttcat
     8341 ataacgacat actggaaacg attttacccc ctgaaataaa agttcatgtc cttgcaagga
     8401 agaaaacgga acaacaccaa gttatttctg cttctcaagt tcgtaaagcg tatcttgctg
     8461 ggcaattgga aaaaataaaa tatatggttc cagaaacaac ctatcaatac ttaaaaaata
     8521 aaagggagcg ttaagtaatg gaaataaata aatcagcgat tgctggaaca ttagagtcaa
     8581 gtgatgtcca aatcatgatt tcaccgaata cagaaggaat agaaatcgat ttagacagtc
     8641 aagtgattga gcaatttgga aaacaaatca aaaaagttat ctatgacaca ctagcagttt
     8701 atcagattaa aaacgtaaaa ctcaaggtag tagataaagg ggcattagat tgcgttattg
     8761 ttgcacgatt aaaaacagcg atccatcgtt ccttaggtat ccaacaccaa gaaacaccgt
     8821 gggaggttta attagatgat gaaagaacgt ttgagaagaa caatgatgtt tgttccagga
     8881 aataatccag cgatgatcaa agatgcaggt atttatggtg ctgactcgat tatgttcgac
     8941 ctggaagatg cagtgtctat ggcagaaaaa gacagcgcaa gaatgcttgt ggctgaggca
     9001 ttgaaaacag tggattatgg tgacacagaa ttaattgttc gaataaatga cctgcactca
     9061 gaatttggac gtgcagacat ttttgcaatg gttaaagccg gcgcgcatgt attacgttta
     9121 cctaaaacag aaacctctga agatataaca gaagtagaaa aagtgattat agaagcagaa
     9181 aactatcata atgttccgat agggcgaaca ttgatgatgg cagccattga aggtgcttct
     9241 ggtgtattga acgcacctgc gatcgccaaa gcatctgatc gattgattgg aatcgccatt
     9301 ggggcagaag actatgtgac aaatatgaaa accaaacgat atccagatgg aaacgaattg
     9361 ttttttgctc gcagtatgat cgttcatgct gcacgtgcag caggcatttc cgcatttgac
     9421 actgtttact ctgatgtgga tgatatggaa ggatttttaa acgaagtacg tttaatccat
     9481 caattaggtt ttgatggaaa atcttgtatc aatccacggc aaattccagt agtcaatact
     9541 gtttatcagc cgtcaatcaa agaaatcaaa cgatcactag acatcatctc ggcaatcgaa
     9601 gaagcaaaag aaaaaggttc tggcgtaatt tctttaaatg gaaaaatgat cgataaacca
     9661 attgtagaac gtgcacaacg gacattgatg ttagcaaaag catcacgatt gattgatgag
     9721 gagggaaata tccatgcata ataaacaaag acgtagcatt ccatcaagtg ttttaacaaa
     9781 gtataaaaaa gaattccaaa gtgtttcatt atcgccacaa acgattcaac gttgtgcacc
     9841 aaaagtaacg actgtaacta atcagacaaa taaattgatg cactcgatca aagaagctat
     9901 agaaaaatcg ggcttaaaag atggaatgac gatttcattt catcatcatt tgagagaagg
     9961 tgattttgtt tttaaccaag tgatggccgt gatccgtgaa atgggcatca aagaattgac
    10021 cttagcacca agttctttaa cgaacactat gaatgagatg gttattgaat gcatcaagga
    10081 cggtacagta actcatatca caagcagtgg gatgcgcggc agcttaggtg aatttatttc
    10141 tcatggagga atggacaatc ctgtgatttt acgttctcat ggtaatcgtc cacgtgcaat
    10201 tgaaagtggt gaattgaaaa tcgatgttgc atttctagga gtaccaacat ctgatgatta
    10261 tggaaatgct aatgcgactg ttggaaaatc cgtttttggt tcattagggt atgcaaaagt
    10321 agatgcacaa tatgcagata aagtcattct tctaactgat catttagttc cttaccctaa
    10381 tacgcccatt agtattccgc aaacacaagt cgactatgtc gtggaagtag aagcaattgg
    10441 tgatccgaat aaaatcggtg ctggtgctac acggtttact aaaaacccaa aagaattaaa
    10501 aattgctgaa atggtcaaag atgtcattgt tcactcacct tatttcaaag atggcttttc
    10561 ttttcaaaca ggaacgggtg gtgcagcttt agcagtaacg cgttacttag ctagtgaaat
    10621 ggaagaaaaa cagatcaaag cttcttttgc attaggtggc atcactaaac caacggttga
    10681 tttattggaa aaaggtcttg ttgaaaaagt gttagatgtc caagactttg acaaaggagc
    10741 agctgaagga atggcgcggc ttgagaacca acaggagatc gatgcttcct tttatgctga
    10801 tccaagtaat aaaggagcgg ttgttaacca attagatgtc gctattttat ctgcattaga
    10861 aattgacaca aacttcaatg taaatgttat gactggttca gatggtgtgc taagaggtgc
    10921 gattggtgga catcaagatg cagcaacggc taaacttact atcatctcag cgccgttagt
    10981 acgtggccga atacctacag tagtaaatga tgttactaca ttgatcacac cagggaaaag
    11041 tatcgatgta ttagtcacag aagtaggggt tgctatcaat ccccaacgta aagatctaat
    11101 agctattttt gaaagaattc cacaaattcc tgtttttaca atagaagaat tacagcaaaa
    11161 agcagaaaaa atagtaggca tcccggaacc tttgcaattc acagatcgga tagttgccta
    11221 tgtagaatac cgagatggtt caattttaga tgtcgttcgt caggtgaaag aatttgaaga
    11281 agagagatca tgatgtttga tactggagaa attcaagaaa tcgaggatat tttgatccat
    11341 aaagaacaac gtgctaactt gcaaagcaac ctgctttcca agtattcaaa tagttcattg
    11401 atggtcttta cattgaatat tcctgggccg atcaaaaata atccaatgat tgagcaggta
    11461 tttcgtcagg gacagcagtc aattcagcaa atgtttttaa aaaaaaaggt ggaaatgacg
    11521 tacacaaaag aaatcaattt gccaagtgga ttggactggt acgtaatagt aacagaagca
    11581 cctttgaatc tcaaaaaatg gttggtcacg ttagaagagc aagacgcatt aggtagactt
    11641 tttgatttag atgtcttgtt caaaaaagga gagcagataa caattgtcag tcgccaagct
    11701 cttaatcatg gggaacgtcc ttgttttatt tgtgggaaat cagcaaaggt atgtgcacgt
    11761 aatcgtacac atactgtgaa agaaatgcaa aagaaaatcg aacaaatagt agccgattcc
    11821 ttaaaaggag cattgaaaca tgcatgataa tattcaaaaa atagcacaag aagcacaatt
    11881 agcgatgctt tatgaagtta catgtatcaa taaaccagga ttggttgatc cagtagaccc
    11941 cgggtctcat caagatatgg acatttttac ttttctacaa agtagtgtag ttttgactcc
    12001 ctattttgaa gaatttatcc aaacaggatt ggaccgacaa catcaaccaa ttgaagaaac
    12061 ctttatggcg attcgacaga ttggtttaga ggctgaaact gcgatgttct cagtgacaaa
    12121 tggtataaat acacataaag gtgctatctt ttcattgggg atttttcttg ctatttgtgg
    12181 ccggttaact atttggaaag ttccttgtaa aaaaagtttc tttcaaaaag aaattcaaaa
    12241 aatgacgaaa aatctactta acgattttgg gaagattgat caaacaaaac caaaagcatg
    12301 gacttgggga gaatatctat ttgttaacca tggattgaca gggatacgag gggaagccaa
    12361 aagaggttat ccttgtgttt ttgaccgagg attgccttat tatcaagcat atcaagggtc
    12421 gcaacaagat aagatgatag acactttact ttttctatca atggaagtag aagataccaa
    12481 tttgatcaaa cgaagtaata atagacatgt ttttgaagag tatcaattac ttattcgtcc
    12541 ttattttgaa ttagggggtg taaaaaccat acaaggtaaa aaatatttgg attacctaaa
    12601 tcagcaattt aaaaagaaaa attggagtat tggtggaagt gcagacttat tgatccttac
    12661 aatcttttta gataaaatca tggacaaagg atggttatgt tgatactata atacattatt
    12721 ttgtattagt aagctaataa ctaaaaaatg gttcaataca aatattttat aaaaaatggt
    12781 agtgcctatc ctttcagatt gtagacaaag aaaaatttct ttgtctacaa tttttttgtt
    12841 aatgacttca gtcagtttcg tgcgcaaagc gtgcgaaaca agaaaaccat gcgtttctac
    12901 acgtggaaga actagcatat cgaaaggagt tttttcatgt caaatgacga taaaagttta
    12961 gcccatactc gttggaattt taagtatcat attgtattta caccaaaata tcgacgaaaa
    13021 gtaatctata ggcaattacg aaaagatatt ggaaaaatac ttaggaagtt gtgcaaaata
    13081 aaaaacgtgg aaattataga agcacatgca acgccagatc atattcacat gcttgttcaa
    13141 gtaccatcaa aaataagtat atccagtttt atagttatct gaaagatcgt agtgctgtgc
    13201 taatccacga gcagcacgta aatcacaaat atagatacgg aaataaatca ttttggtcgg
    13261 aggaatatta tgtgagtaca gtcgaattga atcaaaagac aattgaaaaa tacatccgtg
    13321 aacaagaagc tgatgatcgc atttgagata gtataagtaa aagagagtag atgttgcaat
    13381 aacaaaaggg taaaaatgga ctacctccag taaaataccg aaaaatagtt taacttttgg
    13441 agataagtcc atttaagggt ctatagaatg acaatttttt taggggattt tactattatt
    13501 acttcaagac ccgcttggat tcgcaaagtg agtgaactct taaaactacc tgatagtagg
    13561 ttgttttaag agttatctga aagtaaaaat tgcatttata tttttgataa atacgtaaat
    13621 ttatatatac gtatttatca aagttttagg ccaaaggaat attgtgtaaa tacactagga
    13681 ttgaatgaat agaccagaag aaattgcgtc caagaacaaa agaagcatga tagtgctcta
    13741 tataaattgg gcattcaaga atctgaaatt taaaggtaga attttagtta gacttttaga
    13801 ttttaaacac aaaaataacc atacaagcaa caagaagcaa agtgctatat tataaattgt
    13861 ccgtccgttt acttacataa gatcattggg gctattttta aaagagaata atagataata
    13921 aatgaaaaaa aagtcaagtc cacaatcctg tgtaaaatac tatacaatgc tctcactatt
    13981 ttttacttgg caaatttaat atattttctt gatgaagaaa gccactcatc gtgttgatca
    14041 ataaggactg ctccaattaa acgattggct gaaacgcagt ttggaaagat acgaataatt
    14101 ttttctcttc tgcgcacttc ttgattcagt cgttcaatta gattggtact ctttagtcga
    14161 ttgtgggaat ttccttgtac ggtatattga aaggcgtctt cgaatccatc atccaatgat
    14221 gcgcaagctt ttgaatattt tggttgatcg atataatcat gaatcaatcg atttttagcc
    14281 tcacgagcta agttaatatc tgtgaactta aaaattcctt taacagcttc tctgaaagat
    14341 tttgaatttt ttttaggaat ggtggtaaag atatttctta ggaagtgaac ttggatcttt
    14401 gccaacttgc gttggtgaag gattttctaa tggcagagac taatcctttg tgcgcatcag
    14461 aaataacgag ttctgtacct tgtaaaccgc gttcttttag gtattcaaaa a
//
LOCUS       DAFEKH010000068        14136 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.071, whole genome shotgun sequence.
ACCESSION   DAFEKH010000068
VERSION     DAFEKH010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14136
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.071"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            66..767
                     /locus_tag="LP386_002421"
     CDS             66..767
                     /locus_tag="LP386_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HBL1919628.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            764..1885
                     /locus_tag="LP386_002422"
     CDS             764..1885
                     /locus_tag="LP386_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBL1919629.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            1900..3132
                     /gene="pepT"
                     /locus_tag="LP386_002423"
     CDS             1900..3132
                     /gene="pepT"
                     /locus_tag="LP386_002423"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HBL1919630.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            3264..4172
                     /locus_tag="LP386_002424"
     CDS             3264..4172
                     /locus_tag="LP386_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HBL1919631.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            4207..4479
                     /locus_tag="LP386_002425"
     CDS             4207..4479
                     /locus_tag="LP386_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HBL1919632.1"
                     /translation="MDVLLHNLLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            4490..5536
                     /locus_tag="LP386_002426"
     CDS             4490..5536
                     /locus_tag="LP386_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBL1919633.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            5787..8396
                     /gene="clpB"
                     /locus_tag="LP386_002427"
     CDS             5787..8396
                     /gene="clpB"
                     /locus_tag="LP386_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HBL1919634.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQPNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(8547..9233)
                     /locus_tag="LP386_002428"
     CDS             complement(8547..9233)
                     /locus_tag="LP386_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919635.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(9211..9705)
                     /locus_tag="LP386_002429"
     CDS             complement(9211..9705)
                     /locus_tag="LP386_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBL1919636.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(9725..10945)
                     /locus_tag="LP386_002430"
     CDS             complement(9725..10945)
                     /locus_tag="LP386_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1919637.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            11092..12927
                     /gene="lepA"
                     /locus_tag="LP386_002431"
     CDS             11092..12927
                     /gene="lepA"
                     /locus_tag="LP386_002431"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HBL1919638.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEDEPKK"
     gene            complement(13021..>14136)
                     /locus_tag="LP386_002432"
     CDS             complement(13021..>14136)
                     /locus_tag="LP386_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL1919639.1"
                     /translation="FVSLNYTNGEDINDDGSRKKVEKVGGDTRPEAEAALRKVLSDID
                     ETGQYFLGTDTRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLS
                     PALLQNFINAEFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEAR
                     PTTKKDLKIISLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNG
                     TITVEKQMVKNDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYI
                     DSNAVCTKEDGELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEIS
                     ERLGHSRISITMDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT         4564 a         2598 c         2926 g         4048 t
ORIGIN      
        1 ttttttattc ctagtctcct tattttattt ggaaaatgct ataattatct agaaggagtg
       61 aagctatgaa ccatttagat ttatctcagc gcttagccgc agtgggtgac tttgtccctg
      121 aatccgctcg tttagcagac attggatcag atcacgctta cttacccgtt gcattgatat
      181 taagaggaaa aatcgaatat gcagttgctg gtgaagtcgt tcaaggtcct tatgaatcag
      241 cacgtaagca agtcaaaaaa gatggattag aagaccgtat caccgtacgc cttgcaaatg
      301 gtctagatgc tatccagcca caagatggta ttacagctgt cacgattgcg ggtatgggag
      361 gttcactgat ccgagatatc ctagaagctg gcaagttgaa tcaacgctta agcggacaag
      421 aacgtttgat ccttcagcca aacatcggag agcgtacatt acgatcttgg ctgcaagaaa
      481 atcagtataa aatccaatca gaaaaaatac ttgaagaaaa taaaaaaata tatgaaatca
      541 ttgtagccga aaaagaacaa aaaccagtta cttacaatga aatggagctg atgttcgggc
      601 catttctgct tgaagagaaa agtgagatct tcaaatcaaa atggacaaga gagcttcaac
      661 aaagaaaagc tatccgtgaa cagctcaaac aagcagctaa tcaagaggca cgtcaaaaac
      721 aaatcgagca ggaaatccaa atgattgagg aggttttaaa gccatgacaa tcagcggacg
      781 cactttcatc caaaagtttg aaagctattg tcctcagtgg ctagctgaag aaggagaccc
      841 agtcggactg catatcggaa cattggataa gccaatccaa cgagtaatga tgacattaga
      901 cgttcgtcca gaagtggtcg aagaagcaat caagaaaaaa atcgatttgc tgattgctaa
      961 acatcctcca atctttcgtc ctgtaaaacg gctggttact gatcagccac aagaaaaaat
     1021 gtatgcagat ttgttgaaac atgatattgc cgtctatgca gcacacacga acatggatat
     1081 tatttgggat ggactgaatg actggttttg tgaacttctc ggtattgaag tggagagtta
     1141 tttagtaaag actcatgaga ttcattataa aaaactggcc gtttatgtac ctgtggatca
     1201 tgcacagaaa atgcgtgaag tattagctgc agctggtgct ggtacacaag gtgattatac
     1261 cggtacaagt tttacctcga ttggacacgg tcgatttact ccggaagctg gtgcacaacc
     1321 agcgattggg aaagtaggga agacagaaca agttcaagag gcaaaagttg aggttatttt
     1381 gccggaaact atcgaaaaac aagtgattca agccatgcgg tcagctcatc cttatgagga
     1441 acctgcttat gatcttttcg ctatagatga accagtcgaa atgtttgggt taggacgagt
     1501 aggtgaattg ccgcaagaaa tttctataga ggcatttgta gaacaagtaa aagaagcgtt
     1561 ccaactagat ggactgagaa tagtccagcc aaaaaatgca aaatcctctg tgaagcgcat
     1621 tgcgatttgc ggtggaagcg gtgaaaaatt ttatccgcaa gcaatcgccc aaagagcaga
     1681 tgtctatatc acgggagata tctattatca tacggctcat gatatgcaaa gcgctgggtt
     1741 gattgcaatt gatcccggtc attatattga atcgttatgc aagcaacgat ttatcgagaa
     1801 atttgaatct tggaaacaag aagaaaattg ggatattaac tttttcgttt ctgaaacaaa
     1861 tacaaaccca tttcaattta attaaaagga gagaatacta tgtacgaaaa tcttttgcca
     1921 cgttttttac gatatgtcaa aacagaaaca cgctccgatg caacaagcaa aacgactcca
     1981 tcgactcaga cacaagttgc ttttgcgcaa gaattgaaaa aagaattaga agagttaggc
     2041 ttagctgatg ttttctataa tgaagataac ggattcgtta tgggaacatt accaagcaat
     2101 gttgatcatg aagtgcgttc cattggattt atttcccaca tggatacagc agattttaat
     2161 gcagtaggag tcaatccaca aatcattgaa aactatgatg gcgagtctac gatcgtacta
     2221 gatgcggaag aacgctatac attgaataca aaagattttc caaatttgaa aaattatgaa
     2281 ggccacacat tgatcacaac agatggcagt acattactgg gagcagatga caaatcaggg
     2341 attgcggaaa tcatgactgc aatggagatc ttgatcaata atccttctat ccctcacggt
     2401 accatcaaag tggcttttgg tcctgatgaa gaaatcggtg tcggagcgga taaattcgat
     2461 gttgagcaat tcgatgtaga ttttgcttat acagtcgatg gtggtccttt aggtgagttg
     2521 cagtatgaaa cgtttagtgc tgctcaagca aatattacga tccaagggaa aaatgtacat
     2581 ccagggacgg caaaagatac aatgatcaat gctctacagt tagcaatcga ttttcataat
     2641 cagcttccag ccgatgaagt tccagaaaaa acggaaggat acgaaggttt cttccatttg
     2701 atggcattgg atgggaatcc tgaagaagct tctatgagtt atatcattcg cgatcatgat
     2761 cgtgaaaaat tcgaagcacg caaagcacaa atcacacata tccaagaaga gttgaatcag
     2821 cgatttgatc aagaacgaat caaagtagat atgtatgatc aatattacaa catgaaagaa
     2881 atcattgaaa aagatatgag catcgtggaa ttagcgaaac aagcaatgat cgagcttggt
     2941 atctctccag tgatcgaacc agttcgtgga ggaacagatg gttcaaaaat ctcttacatg
     3001 ggtattccga cgccaaatct atttgccgga ggagaaaata tgcacggacg attcgaattt
     3061 gtttctttac aagtaatgga aaaagcaaca gacgtgattg taaaaattgc agaattgaac
     3121 acaaagagtt aaaatcgaaa aagaacagct tatgacaagg cgttcgtccc aatgatggaa
     3181 tgtcatctgt ctaaggctaa agggcaggac aatggaattg gttgtcccgc cctctttttt
     3241 gaagagtaaa taggaggtaa agaatggaaa agctgctagt tttttataac aaaagttcag
     3301 ggaaagatga gggtgagaaa ttagcacgct ggtttcaaga ttatgtaaaa gaaaagcagc
     3361 cagaattata tgtagaacta gctgaaactg gcccatcgat tgatgatgcg gaattagtca
     3421 agaaagcaga agccatagaa gctgatactt tagtaattat aggtggagac ggcacgattc
     3481 atcatatcgt ccaagcgttc caaaaaacat tatctcaata ccatgtcgga ttacttccag
     3541 gtggaactgt caacaacctt gcacgtgttc ttgagattcc cctcaaaaaa gaagaagctg
     3601 ctgacgtgat cctggaaggc aatgtacgga aaatagacta tggtcaagtc aatgatgaag
     3661 tcattatctc tacactgaca atcggaatct tagcagatac agcagtttgg atcagtcaag
     3721 aagaaaaaca gcgttacggc tcgtggatct ttatcaagaa gttttttaag ttattgctga
     3781 agaagaaaaa atatcatttg gatttagaaa cagacgagga gcattggaaa ggaaaatccc
     3841 aactgttgac agtcacgatg tctaactccg tgggcggttt tacaaatttt gacgactcag
     3901 cgaccctaga tgatggaaaa tttcatgtaa cgatcgtacc ttccttagat attttccgat
     3961 ttatttttta tttgcctaga atcatgagag gcaaattcta tacgatcccc ggcattactt
     4021 atttcacagc caaacgcatg aaaatccaag cgcaggaaaa atctgtgggc actcgaacgg
     4081 atggagacac gacagatgat cttccagttg aattatctgt tgtatcaaaa ggattaacag
     4141 tttattcacc aaagaaagaa gaaaaagctt agaaatagta gttaacagaa agttggaaga
     4201 agagtaatgg atgtattgtt acacaatctt ttgtggtttt accttttcat tgtgaatttt
     4261 tacttatttt gtctgatggg gtatgataaa catcaggcta gaactagcgg ctggcgtgtt
     4321 cctgagaata atttgatatt tgtcagcctg ttaggcggtg gtttgggagg attgatctct
     4381 cgaaaagttt tccatcataa aactcggaaa aagaagttta ctataggatt cgctgcaggt
     4441 gtacttgttg atttgattct catttatttt ttccattaag gagcaggaga tgtcgtctaa
     4501 aggaacgaaa actaaaatca ttctgaatct gcttttgctg attgtgattt ttgccattat
     4561 ttattattta atcaatcaat catttgcaga tatctttgcc gaattgctgt ctaccagtgt
     4621 tgttgttttg gcagcggctg ttatattagg gacagtttac caaatcgctg aagggcgctc
     4681 aatcaaagaa attgctgaac ctttcgcgcc gaattttaca acgaaagatg ggttcttgac
     4741 ctctagctat attgcgtttt accgaatcgt ttcgtttggt acaggaacgc tgatctcgga
     4801 gatttatttt tataacaaaa aaggaatgaa gctatcccag ggagcagggg tgacagcact
     4861 ccatatgatt atgtacaaac tggcagtgat cacttatgca ttagctggct tggtcatcca
     4921 attctctctt ttttattcta atggtccatc aatgatctgg tttatcatcg ctggtatcct
     4981 tttgacgatc gtgattgttg cctttttatt ggcgatgtcc gtcagcttga atgttcaaat
     5041 attttttgtc agcttatcga ataagttatt taaaagtgag cgtttgcgga aatgggtgga
     5101 tacatgcaat cagcagatct actctttaag ggaaacggtc caaaccatta tccaagacag
     5161 gactgcgcta ttgcggattt atctatggaa tatgttaaaa cttgtatttt ggtatgtact
     5221 tccttatttg attctgattg aaaaccatcc taaaatagat tttctactga ccatttcgtt
     5281 tatcagcttt gcagtagtgc tttcaggggt tattcctacg cctgctggta ttggttcctt
     5341 tgaatttgtc tatttgttat tattcagacc agttgttgga acagttgacg cagtttcttc
     5401 gcttttactg tatcgtttca gttcctttat cttgccattt ctctatggat ttgtgtatgt
     5461 gattgctgaa cggcgaagag tgatcaaaga agaaataata gaagtaaaaa aagagaataa
     5521 agaaaatcaa gggtaggtct tttataagat ctaccctttt tatcaaatca aagaaaaacg
     5581 ttatggataa gataatttta cgtttgtttg gctctttttt tatatacata caatcaattt
     5641 tgttttttta agatttatat aagtcgagaa aaaaagtcaa aaaaccatgt gtatattttg
     5701 accaaaattg accaaagcga tataatagtt tttgtaaaga tcaaagaaat aagtgatctt
     5761 acctttaatt aggagggtat acctgtatga atattgagaa aatgactacg acgcttcaag
     5821 aagcgattgc tgaagctcaa cagattgcgg tcactcgaaa acatcaagat atcgacattg
     5881 cccatgtatg gaaaatcttt ttacaaccta atcattttgg tcgaaatttc tatacggatg
     5941 ccggattgga tgtcgaatct tttgaacatg aaattgatcg tctactggat gagtatccag
     6001 ttgtttctgg tggaaacgtc caatatggac aaaacctcag ccagaatttc tttcgattat
     6061 tgaatgaagc agaccaaata cgtgaaagct tcggcgacga gtttctttca acggaagtcg
     6121 ttattttagc gttgatgaaa ttaaaaaatt atccgttaac tgtttatttg aataaaaacg
     6181 gattatctga aaaagaattg cgtaaaaaca tcgaagagat gagaggagga gaaagagtga
     6241 cctcacaaaa ccaagaagaa caatacaaag cattagaaaa atacggcgtt gatttagtac
     6301 agcaagtcaa aagcggaaaa atggatccaa tcatcggtcg tgatgaagaa atccgtgatg
     6361 tcatccgtat tctttcacga aaaacaaaaa ataatcctgt tctgatagga gaacccggtg
     6421 tagggaaaac ggcaatcgtt gaagggcttg ctcaacgtat cgtacgcaaa gatgtgcctg
     6481 aaaatttaaa agataaaacg attttttcat tagatatggg tgcattgatc gctggagcaa
     6541 aattccgtgg tgaatttgaa gaaagactaa aagcagtctt gaaagaagtc aaaaaaagtg
     6601 atggacgtat cctcttgttc atcgatgaaa tccacaatat cgtaggggca ggaaaaacag
     6661 aaggaagtat ggatgccgga aatctgttga aaccaatgct tgctcgcggt gaattacatt
     6721 tgatcggtgc cacaacttta gatgagtacc gtcaatatat ggaaaaagac aaagcgttgg
     6781 aacgtcgctt tcaaaaggta ttagtcaaag aaccaacagt ggaagatacg atcagtattc
     6841 tgcgtggatt aaaagaacgt tttgagatcc accatggtgt taacatccat gacaacgcat
     6901 tagtagcagc agctacttta tctgaccgtt atattactga tcggttctta ccggacaaag
     6961 caatcgattt gatcgatgaa gccagtgcaa cgattcgggt agaaatgaac tctatgccaa
     7021 cggaattaga tcaagttact agacgtttga tgcagttgga aatcgaagaa gctgcactga
     7081 aaaaagaatc agatgatgca agtaaaaaac gcttgaaaaa tttgcaagaa gaattagctg
     7141 aacttcgtga agaagcaaat gcgatgaaga tgcagtggga aacagaaaaa gaagaagtca
     7201 attctgtttc agcaaaacgt gctgaaatcg ataaagcaaa acacgaatta gaagatgcag
     7261 aaaataacta tgatttagaa cgcgctgctg tattgcgtca tggtacgata cctcaattag
     7321 aaaaagaatt gaaggaatta gaagctaaag caaaagacag cgagattaag atggttcaag
     7381 agtccgttac cgaaaatgag attgctcaag tcgttggcag attaacgggt atccccgtaa
     7441 cgaaacttgt agaaggtgaa cgagaaaaac taattaaatt gaatgaaaca cttcataaac
     7501 gagtgattgg tcaagatgaa gcagttgatg cggtcagtga cgcggtaatt cgttcacggg
     7561 ctggattgca agacccaaat cgtcctctag gttctttcct tttcctagga ccaactggtg
     7621 tcggaaaaac cgaattagcg aaagcgttag ctgagaactt gtttgactca gaagatcata
     7681 tggtacggat cgatatgagt gaatatatgg aaaaacatgc tgtgtctcgt ctagtcggag
     7741 ctcctccagg ctatgtaggt tacgaagaag gtggtcaatt aacggaagct gtcagacgaa
     7801 atccttatac aatcgtcttg ttggatgaaa tcgaaaaagc gcatcccgat gtcttcaata
     7861 tcttgttaca agtcctagat gacggacgct tgactgattc aaaagggcga gtagtagatt
     7921 tcaaaaatac ggttctgatc atgaccagca atatcggttc acagttactg ctggaaggcg
     7981 tgactgctga tggaacgatt ccagaagcag tggctgaaca agtcaacacg ctattacgtg
     8041 gaaacttcaa accagaattc ttgaaccgaa tcgacgacac gattttattt acaccattga
     8101 gcctagacaa cgtgaaagga atcgttgaca aaatggtggc gcaattggca caacgtctgg
     8161 aacatcaaga aatcctgctg acaatcagtg atgaagccaa aacgtggatt gctgaaaatg
     8221 cttatgaacc agcatatggt gcaagaccat tgaaacgatt tatcactaag gaagtagaaa
     8281 caccactagc taaagaaatc gttgcaggac atgttatgcc taaatcaaaa gtaacgatta
     8341 ctttacttga tggacaactt catttcaaaa cagaagagct agaagaaatc gtctaatctt
     8401 ccattgagac tataaaagaa aaaaggggtc tgacacaact agtgtcagac ctcctttttt
     8461 caaataaaca gtgttccaga agtagtttct tcgaaaaata agccgaaatt tcttgaagct
     8521 gcccgcttct gtcacaacct cttttattag gtatttttca ctttttctaa tttataactt
     8581 tcaaagtaac gctcatcttt tttactttga gaccatgcaa acaatcccat taaggcagca
     8641 cctatcgtat ttgtcagcaa gtcgcccatc gtatccatca atgctgctcg tccgacaaac
     8701 agtgtgccat cagaagcagc aaaacgttga agattcatgc ctaagaactg gtcgcataag
     8761 aattcccaga actcccaaaa cacgccgcaa agtccagcaa acgcaaagcc gaataagagg
     8821 aacaaccaag gactggtttt tgatatctca gcatctttca tcaagtaacc aatcaatcca
     8881 tagccaagag ctgtcaggac cattggactc accgcatgta agattttgtc ccaaaaagag
     8941 atgatactga tcaaatgcat ccctgtgcct aaaaagacag agatgaacaa gaaaaaccag
     9001 taaaacaaaa cgattgctgc tggtatttta agtttgaaaa ctttcaaaat gacttgtggc
     9061 atgaaaatca atgcaatccc taataaagat tccacgataa atgtgattcc ttgagaagtc
     9121 gaatattttt gtgtgataaa ttcataaaaa ttatagcaga caacgaatac accaaaagca
     9181 agtaaagcta tttgcacctt tttgatttct ttaatcactg aaagtccctc catctaaaaa
     9241 tctttttact tctgaaagca actcaatttc tgaagaaacc acttttccgt tcaatttgat
     9301 caaacctatt gtatataagt tcaggtagtg aaattgattt tcagctgttt cttgtagtgc
     9361 agcgattttt ttcgggtggg ttccgccttg ctgtcgagta tcagtatata agccgatcac
     9421 tgggatgcct ttcgcataag ccacaccgat ttccgatgct accccggcat cgatcgtcag
     9481 cccatctagt aaagcaatca ttaaatcact agccaacact ttttctgtgt cagcaagagc
     9541 aatcattcga ctgtctgcat aagcagtttt gtcattgatt gcttcatttt cttgaggaag
     9601 atagatcgaa agctcagaag agagctctct gatttcttta actaactgtt ggttatataa
     9661 caaatcactt ttagcaaaca ttggtgcggc aaaataaatt ttcatctaaa catcatcctt
     9721 tttatcaaaa ataatcgcta aagtaagctt ccatgtttgg aatgatacgc tctagtgact
     9781 tcagtgtttc ttcatctgtt tctaaccgtt cgattcttgc caaataagaa gcacggcgat
     9841 aattcatcat caagcaagtc aatgtttgga tatccagtcg aacggatttt cctataggtt
     9901 catttaagac acggacttgt ccctgttcat cccatgttaa agcgaagaca ccattattcc
     9961 aaggagcgac aggatcttca atgatgaaat gaaaagcatc agctgttcca acaaacggaa
    10021 accgttgaag gaattctttt acatcaacga tccgagccat aaaatatggt tcgatctgct
    10081 ctttgatctg actatcttca atcaaaaatg ctaaaggctc atttttataa atatctccat
    10141 gtacccagta gatcatggaa aaatgtgcgg aaataaagtt ccataagcca tttcgagctt
    10201 cttgatcaag atagaacatt tcttttacgt gaaatatttc ttcagctacc cagtagaaca
    10261 gaacacctct tggttcatgg ttgctatcgt agtagacagc ggctgtgcgc tcatcttcat
    10321 tttcgaaacg ccaatactct tcccaatgaa aatcactgcg gaataaagca ccatggtttt
    10381 gttgggcaaa tttgtcataa acggaaaata cgtctggatg atcaactggt aatcgctcaa
    10441 ccataccact tactgggatt tgtttaggta gctgtgtatc tctgatttta aaggaaagtt
    10501 tatcagacat gatttcccat cctttacgcc gatagtaggg gatactgtaa ggatacaaat
    10561 aagagatcca ttgcttattc ttgcgcatat tatccaatgc aacgataatt agatcttgca
    10621 tcaatccatg gttagcatat tctggataag ttccaactcc agtcacacca cccattttat
    10681 aacgtgcacc gtgaatattg acttcacaag gatagatagc gatttgagag atcagtttat
    10741 tttcgtggaa ccatccgaac actttcgata cttccaaaat cggttttttg gaacggataa
    10801 aagctcgttt attctcaaac ccgctttcct cgatgtctgc ttcagtcact tggaacacat
    10861 aggaaagcaa ttcattgaat tgatcgatat gttcttgagt gaccggtttt aattcaagat
    10921 tttctctaaa atctttttga tccatttttt catctccatt tattagcttg ataacagtat
    10981 agcaaaattc tacaaaaaaa acttctatag ctgactaatt aaaaactctt taaattactg
    11041 cttttcgttg gtataatgga aagtgctgat tatatgaaaa gaggagacgc tatggatata
    11101 aagaaaatga aagaacgcca agagcagatt cgtaattttt cgatcatcgc tcatatcgac
    11161 catgggaaat ctacattggc cgatcgtatt ttagaaatga cgcacactgt gacgtctcgc
    11221 gaaatgcaag atcagctgtt agactcgatg gatttggaac gtgaacgtgg aatcacgatt
    11281 aaattaaatg ctgtagaact caattacaca gcgaaaaatg gagaaacata tatctttcac
    11341 ttgattgaca ccccagggca cgtcgacttc acctatgaag tctctcgaag ccttgctgcc
    11401 tgtgagggtg ccgttttagt ggtcgatgca gcacaaggaa tcgaagcaca aacattggcc
    11461 aatgtttatt tagcgttaga caatgatttg gagatcctgc cagtcatcaa taaaatcgac
    11521 ctacccgcag cagatcccga acgtgtccgt caagaaatcg aagacgtaat cggaatcgat
    11581 gctagtgaag ctgtattagc cagtgccaaa tcagggattg ggattgaaga tattctcgag
    11641 cagatcgtgg aatatgttcc tgcaccaagt ggagacttag atgcaccgct aaaagctttg
    11701 atctttgact ctatttatga tagttaccgc ggtgttgttc taaatgtccg gatcacggac
    11761 ggtatggtca aacccggaga caaaatcaaa ctgatgagta atggcaaaac atttgatgtt
    11821 acagaggtcg gggtcttctc gccaaaagca gttgctagag actttttgat ggtcggtgat
    11881 gtcggttata tcacagcaag tatcaaaact gtccaagata cacgagtagg ggatacagta
    11941 acgttagcag acaatcctgc cgctgaagct ttaccaggtt accgaaaaat gaatccgatg
    12001 gtttattgtg gtctttatcc aattgatact tctcgttaca acgatttgcg ggaagcttta
    12061 gaaaaactgc aattgaatga tgctgcttta caattcgaac cagaaacctc tcaagcatta
    12121 ggttttgggt tccgctgtgg attcctcgga cttcttcata tggatgtcgt ccaagaacgc
    12181 ttggaacggg aattcaatct agaattgatc acgactgcac catccgttat ttaccatgtt
    12241 aataaaacgg atggtacgac tgctacagta gataacccgg cagattttcc tgaacctgta
    12301 acgattcagg atgtagaaga accattcgtc aaagcacaga tcatggtccc aaatgatttt
    12361 gtcggtgcag taatggaact ttctcaacga aaacggggag aattcattac gatggattat
    12421 ttagatgatt accgagtaaa tgtcgtctat aatattccgc tttctgaaat tgtctttgac
    12481 tttttcgaca aattgaaatc aagcacgaaa ggctatgcct cattggatta tgaaatgtct
    12541 ggttatcaaa aaagcaagtt agtgaagatg gacatcttgc tgaatggaga aaaagtcgat
    12601 gcattaagct ttatcgttca ccgagacttt gcctatgaac gtggaaaagc aatcgttgaa
    12661 aaactgaaaa aactaatccc acgccaacaa tttgaggtgc caatccaagc agctattgga
    12721 caaaaaatcg ttgcccgttc agacatcaaa gccttgcgta aaaacgtctt ggctaaatgt
    12781 tatggtggag atgtttctcg taaacgtaaa ctcttagaga aacaaaaaga agggaagaag
    12841 cggatgaaac aaatcggctc cgtcgaagtt ccgcaagaag ccttcatggc cgttctgaaa
    12901 atggacgagg acgaaccgaa gaaatagcaa gggtttgttt gaaaacagtg taaaaaataa
    12961 accatgttta catggatttg ccaccggttt gccaccggtg gtttttttcg gtggcaaaaa
    13021 tcaagaattc tttctaagat tttccatgat atcgaccgtt tcatttctca tcttatctgt
    13081 tacatgcgag taagtatcca tcgtaattga aattctgctg tggcccaatc gttcagagat
    13141 ttctttcatt tttgcgccat tttcgagaag aagtgtagca tgagtatgtc tgagagaatg
    13201 gaagttaaaa gagagggaga gtgcattcga tatcctccta gtattccatt tcactacact
    13261 tggcgtaact agctcaccgt cttccttcgt acatactgca tttgaatcaa tgtagagctt
    13321 tccatacttc attcgatttt ctaattgttg tttcttatgt tttttcagaa ttgctagcaa
    13381 ggtttgtcca ataaaaatcg ttcgattgga actgcttgtc tttggcgtac catataccca
    13441 tgcgccgtca ttctttacca tttgtttctc tacagtaatt gttccatttg aaaaatcgac
    13501 atcatcccac gtcagaccac aaacttcgcc aacgcgcatt cccgtataaa atccaatatt
    13561 caaaggaata tagaaaggat gtccttcagg agtaatttct agcatatgat caaagtcctc
    13621 aagagaaatg atttttagat cttttttagt cgttggtcgt gcttcatatt ttggtatttt
    13681 tacatacagc ataggatttt gcttgattaa tccccaagga taaaccgcca tattcagcgc
    13741 attcttaagg acagagtgag taatagtcat tgttttcttc gagtaaccct ttttaaattc
    13801 agcattgatg aaattttgta aaagagcagg ggagagatcc gtaagttttt tctttcctaa
    13861 ataaccgttt atatgatttt tgatggtaaa tcggtagttt tcataggtat tgtattttag
    13921 atttagttta acgtattcct ccatccaaaa atcaaggtat tgttttactc gagtatccgt
    13981 acctaaaaag tattgtcctg tttcgtcaat atctgataaa acttttcgta aagcagcttc
    14041 ggcctctggt cgggtgtctc cgccaacttt ctccactttt tttcttgagc catcatcatt
    14101 gatatcttcg ccgtttgtat aattaagcga gacaaa
//
LOCUS       DAFEKH010000069        14116 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.072, whole genome shotgun sequence.
ACCESSION   DAFEKH010000069
VERSION     DAFEKH010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14116
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.072"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..554)
                     /locus_tag="LP386_002433"
     CDS             complement(<1..554)
                     /locus_tag="LP386_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HBL1919640.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGA"
     gene            complement(570..1049)
                     /locus_tag="LP386_002434"
     CDS             complement(570..1049)
                     /locus_tag="LP386_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HBL1919641.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKARLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(1055..2079)
                     /locus_tag="LP386_002435"
                     /pseudo
     CDS             complement(1055..2079)
                     /locus_tag="LP386_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
     gene            complement(2096..3202)
                     /locus_tag="LP386_002436"
     CDS             complement(2096..3202)
                     /locus_tag="LP386_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBL1919642.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(3431..6028)
                     /gene="adhE"
                     /locus_tag="LP386_002437"
                     /gene_synonym="adhC"
     CDS             complement(3431..6028)
                     /gene="adhE"
                     /locus_tag="LP386_002437"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBL1919643.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKTMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(6333..6713)
                     /gene="yajC"
                     /locus_tag="LP386_002438"
     CDS             complement(6333..6713)
                     /gene="yajC"
                     /locus_tag="LP386_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HBL1919644.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(6810..7955)
                     /gene="tgt"
                     /locus_tag="LP386_002439"
     CDS             complement(6810..7955)
                     /gene="tgt"
                     /locus_tag="LP386_002439"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HBL1919645.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            8173..8871
                     /locus_tag="LP386_002440"
     CDS             8173..8871
                     /locus_tag="LP386_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBL1919646.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(9039..11678)
                     /locus_tag="LP386_002441"
     CDS             complement(9039..11678)
                     /locus_tag="LP386_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBL1919647.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(12297..13328)
                     /gene="queA"
                     /locus_tag="LP386_002442"
     CDS             complement(12297..13328)
                     /gene="queA"
                     /locus_tag="LP386_002442"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HBL1919648.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            13521..>14116
                     /locus_tag="LP386_002443"
     CDS             13521..>14116
                     /locus_tag="LP386_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1919649.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEA"
BASE COUNT         3956 a         3096 c         2543 g         4521 t
ORIGIN      
        1 gcgcctacga gataacctcc cataaacaaa gcagagatcg aagcaccacc agcaacaagt
       61 gaatacatga taaaagcagt acttggagga atgaccatac ctgtcggagc tgacgcgata
      121 ttgaccgctg tcgcaaactt ccggtcatat ccttcttcca cttgctgagg gatcaacact
      181 ccaccaatcg cggtagaagc ggcaatggcc gagctagaga tggaaccaaa taaagcattc
      241 cctaacacat tcgtatgagc caaagccccc ggcacgcgcc cgacgaacaa catcgcaaaa
      301 tccactagtt tcttagctat ccctccatta ttcatgataa tgcccgagag aacgaaaaac
      361 ggaatagcga tcagcgaaaa actattgata cttcccacca ttttttgagc tgaactaaaa
      421 gcagaaacat caaacggtat aactaacaat aaagtcatca tcgatgagaa tgcaatactt
      481 atagcaatcg gcatccctaa tacaagcaac acaacaaata caaaaaataa cactaatccg
      541 gcttctattg ccattttatt cctccatttt tatatttttt cttgaattgc tggcttgttg
      601 cttaatgtat cgattagatt gatcaggcta tagataatga tgagtacccc cgatacaggt
      661 actgacagat aaacatatcc cataggaata cttaaagaag gcgagatctg ccccattgtc
      721 aatgtgacag cattccatcc gccatacacc atgatcatcg cagcaaatac cagaaataaa
      781 ctttgaacaa caacttctaa aattttactt tttttgccag ttaatttttc acttaaaacc
      841 gttacggcta aacgtgcttt ttgtcccaca acatacgcgg aagacaacat ggcaaaccag
      901 acaagaccga atcgaacaag ctcttccgtg accgtatttg gatttcctaa aaccgttctg
      961 gaaaatactt gccataaaac aacagcgacc atcccaacaa gcaaaacagc tcccaggatc
     1021 tctaatacct tgtttaaaat cattttcatt acagctacgc tccttgctct tggatctttt
     1081 gataaaggtc tttgtaggta ggatcgtttt tgaatatatc atgaagtggg gcaactgcct
     1141 ctcgaaacgg tgtattatct acatcattga attggactcc atgttcttct tgtgctaaag
     1201 ctttttcttc ttcaattgct tttgcaaaag cttcaatttc aaaaaccgtt gattctttcg
     1261 ctgcttcttc aatggctttt tcctgttcat cagttagctg ttctttgatg gcatcattca
     1321 tgatgatgat atctggcaca cgtgtatgct catcatagga atagtattta gctaccccgc
     1381 catgtccagc tgtatacaag acaaattcat tgttttctga tccgttgatc aaattggatt
     1441 gaagagacgt gtacacttca tcacttccca taggtacggg cgaaccgcct aaaagctcta
     1501 ccattttgat agcggtttcg ctttgcatca cacggatctt ctttcccttc aaatcttccg
     1561 gcgtatggat cggaccgtct accatataaa agctgcgctg accagaatca taataggtca
     1621 atccggtaaa tcctaaattt ttggtcgatt ggtagattgg ctccattatt tcttcattat
     1681 ccatcacctt aaagaaatgt tcttcatcat tgaatagata aggaacggaa aaaatcgaat
     1741 aatctttaga gaaactttcc aacgctgagg cacttacttt tgtgaaatct actgctcctg
     1801 actgtgtcaa ttcgatcagt tcacgttctc cacccagttg tccatctggg aaatactgga
     1861 tctgtacgga accatctgtt ttttctttta ctaaacgccc aaattcattc attgcatcaa
     1921 ttactggctg ttgcttgcat aagcaaagcg caaggtaact atctcattta cgtctgcatc
     1981 tgcgacagtt gccacactag aattatttcc gcagccgctt agacctagca gacctaggct
     2041 aagcgaactt gctgcaaaca gcagtgatgt ttttttcata tgggtttcct ttcttttaac
     2101 aataagagac gagcaattct gtcaaacaaa gcaccgttaa cgactgtcca taaggcattg
     2161 ctgtgattcc gatattccga taaaaatcta aactgtcccc cattcctgtc ccgattgaaa
     2221 cgttttgaac ttctcctttt tcatcgattt gttcaagcaa tccttggata gcacgataag
     2281 cgacttcttt atattcttgt ggtaaataac gtttatggac cgctttcaaa ataccgtaag
     2341 caaatcctgc agttgcagaa gattctacgt aagaagaagg atcatccaac aacgtatgcc
     2401 ataaaccgct ttcagactga taagttttta atgcacgcac ttgtgcttca agtgtttcga
     2461 tcaataattt gcgcaatgca tcttctttcg ataattctaa gatttcaatg atctctggaa
     2521 tagcaatcgt caaccagcag tttccacgag cccaaaatgc ttcggcatag ttatgatttc
     2581 cttcaaacgt ccagccgtga taccacaatc ctgttcgttt atccatcaag tatttgatat
     2641 ggatcataaa ctggtaacga gcttcttcta aatattctgg gcgattcaac agtttcccga
     2701 tttttgccaa aggaagcact gtcatcatca atgtatcgtc ccacaactga ttcttatttt
     2761 ccggtccata tgtggcatgc tgtaacccgt cttcatttgt ccgaggcatg tcattcatga
     2821 cccattctgc ccattgttct aaataaggca aatagcgtga atctttcgtg tcttcataca
     2881 agtaagccat agtcaatagc ggtgccattg tattgacgtt tttgggcgga gcgccttctt
     2941 ccatacgatc ctcaaaccat tcattgacca cttgataagc gcgaggattt tttgtcatct
     3001 ggtaattttt ataaatacca tatagaccga caccttgtgg ccaattccac actgtccagc
     3061 ttttgtcatc tactttcagt ccatcaaagt ccaacaaaaa ttcaccatta tcgtctttga
     3121 tcgttgtcag gttttcaacg agcaggtcaa ttttttcttt cactaattct ttaggtacaa
     3181 aaatctcttc tttaataatc atctttacgc caccttttta aacgctttca ttttatatcc
     3241 ttaatatagc agtaataccg tccactataa atatcgcttt ttgaacaaaa actgtctaaa
     3301 attgacctaa atgttaaata acaaaagtaa ctttcagtta cttggaaatt aaaaaaagaa
     3361 cttggagaaa caacgttttc caagttcttt ttcatctatt ttcttatctt ttttctacgc
     3421 tttcttttgc ttatccgttg taagcatcaa tgatgatctg tttcaattca gagatcaatg
     3481 gttctttcgg attagctgtc gtacattggt cttcgtaagc taattcagcc atacggtcta
     3541 cggttgtatc tagtgtttct tgtgtgactc cttgagcttt tagactcatg ttgatgccga
     3601 cagattttcc taattcataa acagccgttg ctaaagcttc gactaattcc tctgttgttt
     3661 cgcctttcag acctaagaat tttgcgatat ctgcgtaatc tgtatctgca cggaaatagt
     3721 catatttagg gaacatcgca tgtttttgtg gatcttttgc attatagcgg ataatatgcg
     3781 gtaaaagaat cgcatttgtc cgtccatgag ggatcccgta ttccccgccg attttatgtg
     3841 cgactgagtg acaaatacct aggaatgcgt tagcaaacgc cataccagcc attgtagaag
     3901 cgttgtgcat tttttcacgt gattccatat caggtgtttt tactgatttt tctaaatagt
     3961 caaagactaa cttgattgct tgtaggctca atccacgtgt ataatctgaa gccatgactg
     4021 aaacatagga ttcgattgca tgtgttaaca catccatccc ggtatctgct gtgacagatg
     4081 ctggaactga catgacgaat tgaggatcga cgattgcgac atctggcgtc aatgcataat
     4141 ctgctaacgg atatttcaca tgtgtttcac tgtcagtgat gaccgcaaat ggcgttactt
     4201 cagaaccagt ccctgatgtt gtcgggatac atacgaattg tgttttttct ggtttgtcga
     4261 tcttatatgt ccgtttacgg atatccaaga atttttgttt tgcaccaaag aaagatgtgt
     4321 ctgggtgttc atagaacatc cacattccct tagctgcgtc cattgcagaa ccgcctccaa
     4381 gagcgattac tgtatctggc ttgaagtctg ccatcagttt cgttcctgcg tatacggtat
     4441 ttgtcgatgg gttcggttca acatctgaga agacttcgat cttcacatca tttttacgtc
     4501 gtgccaatac ttcacgaact gtatcgcagt aaccgaattg gaccatacca gggtcacaaa
     4561 cgatcatgac acgttcaacg ttttccattt tctctaagta caatagagag ttcttttcaa
     4621 agaagatttt tggcggtaat ttgaaccatt gcatgttatt tctccgtttc gctacagttt
     4681 tgacattgat taagtttaca gcagagacgt tacgagaaac agagttctta ccataagaac
     4741 cgcatcccaa agtcaatgac ggaatcattt cgttatagat atcaccgatg ccgccttctg
     4801 cagatggtgt attcactaaa atacgacaag ctttcattcg aagaccgaat ttgacatgca
     4861 actcttcgtt ttctgaatgg ataactgctg tatgtcctaa tcctccaaga ttcaacatac
     4921 cttcacacaa atcaaacgca tggtccgtgt tgttagcttt gatcatggca agaactggag
     4981 aaagtttttc tcttgatagc ggataatctg ggcctacgcc ttccaattca gcaatcagca
     5041 ttttcgttcc ttttggtaca ctgattcctg ccaattttgc gatttccatc gcagaatgtc
     5101 caacgattga tggattgacc gcatattttc cttcgttcat cactgcatct tctaattttt
     5161 gcaattcatc tggttttacg atataaactt ggtgtgcttg gaattctgct tttactgctg
     5221 catagatttc tttatccacg atcacagctt gttcagaagc acaaatcatt ccattatcaa
     5281 atgttttcga aacgatcaaa tcgttcactg cacgtttaat ttttgctgtt ttttcaatat
     5341 aagctggtac gttacctgga cctacaccta aagctggttt tcctgtagag taagcagact
     5401 tgaccattcc agctccacct gtcgctaaga cgatcgcgat acctggatgg ttcattagca
     5461 tagaagtcgc ttcgatcgaa ggatgttcga tccattggat acaattttca ggagctccgg
     5521 cagcgatagc agcatcacgt accactcgtg ctgcttctgc agaagatttt tgggcacttg
     5581 gatggaaagc aaaaacgatt ggatttcttg ttttcaacgc gatcattgtt ttgaaaatcg
     5641 ttgtggaagt cggattcgtt gttggagtta ctccgcaaac cacaccgact ggttcagcaa
     5701 tttcaatcaa ccctttttgg acatcttcat tgatcacacc aactgtttta tcatgtttga
     5761 tattatgcca aatatattcg gacgcataca tatttttgat tgctttatct tcgtaaacac
     5821 cgcggcctgt ttcctctaca gccatcttcg ctaatggcat atgttgatcc aaagctgcca
     5881 ttgccatttc atgcacgata tggtctactt tttcttgatc aaagctttcc atttctttca
     5941 atgctgcatt tgctttttct gccaaatcat caatcattgc ttgtacgtca attgtcttcg
     6001 ttttttcttt ttctattact ttagccatca ttatcctcct aatgggtcat ggttatttgt
     6061 taaataattc acatgtatat catacaatat ttatttttct atgtaaacac ttttttgtga
     6121 tttttttcac agttattttt aaatataaaa ttgctttatt tacaggtgtt tgtatagaaa
     6181 aatatataaa gttatttatt attatttata tgacacaccc gattattcaa tattgagcaa
     6241 tatatcccat gctcttatct ctttcttttt tgaataaaaa atgaggtagg acatctttct
     6301 gccctacctc gtctttaaat aagctttgat acttattttt cttccttctc ttctgtctct
     6361 tccagcgttt ctgttgtttc agtttttact tcaactgtct cagctggttc ttctgttgtt
     6421 tcaacagtag tcgttgcatc atttgttacg acagtccctg gtttgaccgt tttgattgct
     6481 gcacgatcgt actcaaggaa gatcccttcg cagtctaaaa caactgtccg tttgtcattg
     6541 tcgatttctg aaacaactcc atgtaatccg ccgatcgtta cgactgaatc acctggtttc
     6601 atgctatcta acaagttttg acgttcttgc tgttgtttct tttgcgaacg tgacataaaa
     6661 aaccacattg ctaatagcgc gataaacatc acaagcattg gtaatgttcc catttttttc
     6721 acctcactaa ttctgtatct acaaaaaaca ctttagcaga aaaatgctga taacactagt
     6781 tttttactta atttttaaaa gattttcctt tagaagcttt ttgcgttttc tttattgaac
     6841 ccgtattctt caaaaaaggc ttctctaaat tcaagcaaat tatcatccat gattgcttga
     6901 cgtacttgtt tcattagatt caacaagaag tataaattgt ggtaagaagt caaacgaatc
     6961 ccaaatgttt catcacattt gatcaaatgg cggatatagg cacgtgtata gtttttacat
     7021 gtataacaat cacatttctc atcaattgga cggaaatcat gggcatattt cgcatttttc
     7081 actactagac ggccttgaga agtcatacat gtgccatttc gagcgattcg agtaggcaag
     7141 acacagtcaa acatgtctac tccacggata acaccatcga tcaatgaatc agcagcaccg
     7201 acacccatca agtaacgtgg tttgttttcg gggatcaacg gtgtagtgaa ttctaataca
     7261 cgattcattt ctgatttagg ttccccgaca gataacccgc cgattgagta accagggaaa
     7321 tccatcccga ctagatcttt cgcgctttga cgacgaagat cttcaaaccc tgctccttgg
     7381 atgattccaa ataatccttg acggtctgga ttagcatgag ctttcaatcc tcgttctgcc
     7441 catcgagacg tacgttctac tgattttttc acgtagtcgt aactttcatc gaatggtgga
     7501 cattcgtcaa aactcatcat gatatcagag cccaatttat tttggatgtt gattgctttt
     7561 tctggtgata aaaacatacg cgaaccgttc aagtgatttt tgaaatgcac gccttcttct
     7621 tcgatattcc gcatatcact taatgaaaaa acttgaaagc cgcctgaatc tgttaaaatc
     7681 ggttgatccc agttcataaa tttatgcagt ccgccagctt cttctactaa gtcttcacca
     7741 gggcgtagcc ataaatgata tgtattactt aaaataacgc cagcacccat ttctttcaac
     7801 tcttctgggg acattgtttt tactgtagct aatgttccta ctggcatgaa cattggtgtg
     7861 gggaaagttc cgtgtggcgt gatcaattcc cctaaacgcg cgccagtatg tttttctttc
     7921 ttgattaaac gatagcgaat ggcaggttgc gtcattcatt tccctacttt ctatataaaa
     7981 tatcttgaca actcccacca tcataatcgt ttcaagtgct ttttgcaagt tccctcggct
     8041 tccttctact ttatttaata ttcttttttt tatccttttt ttatgaataa caaaaaaaag
     8101 aaaaacatta tgacagaaat attttttgat acatggtata ttggtgttat taaagaaaag
     8161 gagggaaaaa tcatgcaatc ttctgcagaa ttaaaacgcc aagcaaaaga gagtctaaaa
     8221 ggacgttggg gacaagctgt tttactaaat ctaatcccta cattgattgg tattgctact
     8281 attcttctta ttatgattcc tattatcttg tttgccacca ccatatatga tggatcagcg
     8341 agcgtctcag aagcgacaac ttcaggaggc ggtagttcag gaggcggtgg cggaattatt
     8401 tccagcatca ttagcgcttt gttcatgagc ggtatttctt ggacttatct tgatatttta
     8461 cgtggacaaa aagatcagat cgaaccattc aaagatgcat ttcgtggatt caaaggtttg
     8521 tttatcggcg gagtgatcag cttagctgtg ctgatctcga tctttacaac attatggggt
     8581 ttgctattag ttattcctgg aatcattaaa agctattctt attctcaaag ctattttatt
     8641 tactacgata tcgtccaaga aacaggacaa acacctaaag tactggatac gatcactgca
     8701 agtcgaaaat tgatggatgg ttataaagga caacttttct ggttagatct ttcatttatc
     8761 ggctggcata tcttagcatt agcaactgct ggtattggtt atctatggct cagcccatac
     8821 atttctgcaa caaaagcagc attttatgaa caattgccaa aagatattta aaagagagtg
     8881 tgacttgtga ccgagggggt ggcaggagaa caccgtttat cgagaggcag taaaagaaac
     8941 attcagccca ttagcaaaaa ggaggtgtga caacattcat gtcacacctc ctttttgtat
     9001 agttccagta aaaagaaaat caacttagaa acagttaatc attcctcttc ttctgcttcc
     9061 ggtaatcgat ggaacttgat cagttcattc accgcgattg gtacgataga taaaatccct
     9121 accaagaacc agtgattcaa actgatgtgt actaggccga atagttcttg cgtaaatggc
     9181 agcaaagcaa cagccgttgt aatagctaat gccagtaacg ccatttctac caaagcttta
     9241 ttggtcgcta aattgacttt gaagatcgat tggctgctgc gtacattgaa cacatgcaga
     9301 atcgatgaat aagctaagat caagaatgca acagtttgac cgacatgctg acttgcgtct
     9361 acccatgggc tgatagtatc gacataacta cctaaataat aaccaaacaa ggttacgatg
     9421 gtgaagaccc ctgcatttat ggcaattttt tgcaataaac ctcgagcaaa gatcccttca
     9481 tttttcggaa tgggtggctg atccatgatg ccgtgttccg ctggctctct tcctaaagca
     9541 aatcctggaa gtccatcagc aactacattg acaaacagta gttgcacagc tgtaaatggt
     9601 gctccccatc ctaacagcat cgcaatcaaa acaataaaga tctccgaaat attacagctt
     9661 agcaaaaagt tgatagcttt acgaatattc tgataaaccg aacgtccttg actgacagcg
     9721 tctacgatcg tcgcaaagtt gtcatccgtc aaaatcatat ctgcggcact ttgcgccaca
     9781 tctgttcctg tgatccccat ggcacaccca acgttacttg ctttcaacgc tggtgcatca
     9841 ttcacaccat ccccagtcat cgctacgact gcacccgtac gttgccaaga tttgacgatc
     9901 cggatcttgt cttctggcgt tacccgagca tagacagaga gagctttgac acgcgcatct
     9961 aattcttcgt ctgataattg atgcagttct gatcctgaaa gtgcttctga cggatcattc
    10021 aagataccta attctttcgc tatggcactg gcagtcacca catgatctcc agtgatcatg
    10081 actgttttga tgccagcctt tttcgctcgc ttgattgctc ctttactttc tggacgtggt
    10141 ggatcgatca ttccgatcag accaatcaaa cgtaagtctt tttccagtgc ttcagaagaa
    10201 atatcttgcg gttcttcgtc ataagtagca taaccaacag caatcactct cagtgcccgt
    10261 ttaccaaagc gatcattaac gatcgccgct tgttctacat cgcctgaact aaagcgcgga
    10321 gcaagaacat cgaatgctcc tttggtgatt gagatgtatt tttcgcccat ttggtgaact
    10381 gttgtcatca tttttcgttc agaatcaaaa ggaagctcgt ttactcgtgg atatttttct
    10441 tctaattctg cctttgtatg ataattctct tcaacagccc ttacgatggc tacttctgtt
    10501 ggattacctt tgataacaag gtcgtcatct tcttgctcga ccgtcacatc tgtacatagt
    10561 gcagccattt tcaatatttc catcgcgctg ttcgtcattg aatcttcgat attcgttact
    10621 tcatcttctt tgctccatac ccggcggacg cgcatttcat tttgtgtcag cgttcctgtt
    10681 ttgtctgagc agataacatt agcggttcct agcgtttcaa ctgctggcaa ctgtcggatg
    10741 atcgcatgtt tcctcgccat cttctgcaca ccgtatgcaa gtgtcaacgt aacaataaca
    10801 gtcaaggttt ccggtacagc tgcaacagcc aaggaaatcg aagtcatgaa catctcaagg
    10861 agtggttctc cttgcagttc accaatcaca aatactaaag ccgcagccgc taaagcgatc
    10921 atactgattc gtttgcctag ctgattcaat cggacctgta aaggtgtttt ttgcatagta
    10981 ttttcgttca aaagatccgc gatcttaccc atttctgtag ccatgccaat ggcagtgacg
    11041 atcgctttcc cacgacctgc agcaaccgta catcctttaa ataccatatt aagttggtca
    11101 cctaatgact catcttcttc agcaataaat gctgcatctt tttcaactgc ttcactttct
    11161 ccagtcaacg ccgattcttc tacacgtaat tgtgatgctt cgatcaaacg ggcatcggca
    11221 gaaatagcat caccggactc taaaacaaga atatcaccca ctaccagttg ctctgactca
    11281 acagtggtca ctttgccgtc tcgtatgaca gttgccgttt gtttattcat atcttgcaag
    11341 gattccagtg ctttttctgc gtttccttct tggacaatcg ccaataccga gttgatcaca
    11401 acgatagcga tgatcagcag tccttcaaat aaatccccat gttctgtagc aaatgcggta
    11461 taaaaggaaa tcaccgctgc tacaagaagg atgatcgttg taaaatcgga caagcttcga
    11521 aagaattttt tgatcatcga ttctttcggc gcctcatcga atttattcaa tccctgcttt
    11581 tttcgccgtt catccacttc ttgtgaagac aacccagtat ctggatctgc ttctgttacc
    11641 ttctttactt cttctattgt ctgcttgtat tcttccatcc tattcctcct ttaaaatctt
    11701 cgtacaaaaa aaggtactta ttttactata acatcctttt tttatttact tcaaataaag
    11761 ggcttatcga ttatttgtta agaaagcgta aaatttaaag tgcttatatt tgcaaacgct
    11821 accaaaggat gctattatat agatgtaagg aaggaggata ccatcaaata gacagaagaa
    11881 tttctcgata gaacagtgta agcaaacaaa gttgttagaa gtacaggttt cacccagaca
    11941 tgcgtgtaga gtacaaacct ataaatagtg aatgcgtatg gatgtttgga tcacgaagta
    12001 tccgaaacaa gaagtaatgc gatacgtaac aattgaataa cgtaaacgtc tgaaaattga
    12061 ataggaacaa gagatgtttc aaatgttgaa gatgtaacga aaacaaaatt tttgtttaac
    12121 atgaagaaat tcaacaccgt gctttgcatg tatgatggaa agttacaatc atttctgttt
    12181 atttgaatcc ttccgaggta caagaaagcc gagcttatcg agagctcggc tttttctttg
    12241 tcataaaatc tttgtaaagc ttttttgtta ttcaaaacta gcggcttttc ataaccttat
    12301 ttcacgaaca tcgcatctcc aaaactaaag aaacgatagc gctcttcaat cgcatgctgg
    12361 taagcagata aagtcaattc tcttcctgca aaggcactaa ctaacatgac taaagtcgat
    12421 tttggcaaat ggaaattagt tgagaaagct tctaccactt tgaattcata gccaggcgta
    12481 atgaaaatat cagtccatcc gctgtctgct ttgatttctc cattaaattt cgttccaatc
    12541 gtttctaatg ttcgaattga agttgttccg acagccacga ttttcccgcc atttttacgt
    12601 acttggttca atcgctcagc cgcttcttcc gtcaaacggt agaattcact atgcatatgg
    12661 tgttcttcaa ttttatctac gctgacaggt cggaatgtac ctaaccctac atgtagtgtc
    12721 agatagacta attcaacacc ctttgcttcg atctcatcaa gtaattcttt cgtaaaatgc
    12781 aatccagctg ttggcgctgc agcagaacca ttttctttcg catagacagt ttgatagcga
    12841 tctgggtctt ccagacgttc tttgatatat ggaggcaatg gcatttctcc caatgattca
    12901 agaatctcta gaaaaattcc ttcatactca aagtcaatga tccgtccgcc gtgttccaat
    12961 tcttctttca ctactgcttg caatctgcca tcaccaaaag agattcttgt cccaactttg
    13021 gcacgtttcg caggtttgat caatgtctcc cacgtatctc cttgtgtatt cgttagaaga
    13081 aggacttcta aatgcgcacc agtatctggt ttttctccat ataaacgagc aggcagaact
    13141 cgtgtattat tcataactag cgcatcacca ggctgtaact cttcaatgat ttcatggaaa
    13201 tgtttatctt ccatctctcc agttttccga tccaaaacaa gtaaacgaga atgatcgcgg
    13261 tcttttaatg gtgtttgtgc gattaattct tccggcaagt caaaatcaaa atcttctgtt
    13321 gttaacatat cgtcactcac tttctatcat gtgcttcatc attctatcat gtttttcgtt
    13381 ctgttggcaa aatcagcact ttttcacttc tattttttgt tttcctaaat aaaaaaacta
    13441 ccctatttgt attttttcat tgttttaggc atactagtaa tagatagttc ttcattgaaa
    13501 atagaaaaag aggtggcacc atgattgaat ttcaaaatgt gtcaaaaatt tataaaggtg
    13561 gaaaagtcgc tgtagaggac gtcaatcttt catttgaaaa gggtgagttc atttgtttta
    13621 tcggtacgag cggaagcgga aaaacgacga cgatgcggat gatcaaccga atgactgatc
    13681 caacacaagg gaaaattttg attgatggaa aatccatcca agaaattgat ccagtggaat
    13741 tgcgacgtca gatcggctat gttatccaaa gtattggatt gatgcctcac atgacgatcc
    13801 gtgaaaatat cactcttgtc caaaaattgt tgaaagtcag tcaagaagaa cggaataaaa
    13861 cagctgaaaa aatgattgat cttgtggaat tgccccgtga gatgttagat cgctacccac
    13921 atgaattatc tggtggtcag cagcagcgta ttggagtcgt tcgtgccctt gcagcgaatc
    13981 aagatatcat cttgatggac gagccattcg gtgcgcttga tccaatcact cgtgattcct
    14041 tgcaagacct tgtcaaagat ttacaagagc gtttgggaaa aacgatcgta tttgtaaccc
    14101 atgacatgga tgaagc
//
LOCUS       DAFEKH010000070        13427 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.073, whole genome shotgun sequence.
ACCESSION   DAFEKH010000070
VERSION     DAFEKH010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13427
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.073"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..912)
                     /locus_tag="LP386_002444"
     CDS             complement(<1..912)
                     /locus_tag="LP386_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HBL1919650.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIY"
     gene            1340..1903
                     /gene="efp"
                     /locus_tag="LP386_002445"
     CDS             1340..1903
                     /gene="efp"
                     /locus_tag="LP386_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HBL1919651.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            2004..2174
                     /locus_tag="LP386_002446"
     CDS             2004..2174
                     /locus_tag="LP386_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919652.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            2389..3648
                     /gene="lysA"
                     /locus_tag="LP386_002447"
     CDS             2389..3648
                     /gene="lysA"
                     /locus_tag="LP386_002447"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HBL1919653.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            3635..4435
                     /gene="dapF"
                     /locus_tag="LP386_002448"
     CDS             3635..4435
                     /gene="dapF"
                     /locus_tag="LP386_002448"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HBL1919654.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            4438..5319
                     /locus_tag="LP386_002449"
     CDS             4438..5319
                     /locus_tag="LP386_002449"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBL1919655.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            5316..6032
                     /locus_tag="LP386_002450"
     CDS             5316..6032
                     /locus_tag="LP386_002450"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBL1919656.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            6038..6733
                     /gene="dapD"
                     /locus_tag="LP386_002451"
     CDS             6038..6733
                     /gene="dapD"
                     /locus_tag="LP386_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HBL1919657.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            6749..7750
                     /locus_tag="LP386_002452"
     CDS             6749..7750
                     /locus_tag="LP386_002452"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBL1919658.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINENRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            7747..9108
                     /locus_tag="LP386_002453"
     CDS             7747..9108
                     /locus_tag="LP386_002453"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBL1919659.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            9068..10219
                     /locus_tag="LP386_002454"
     CDS             9068..10219
                     /locus_tag="LP386_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBL1919660.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            10194..11363
                     /locus_tag="LP386_002455"
     CDS             10194..11363
                     /locus_tag="LP386_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBL1919661.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            11538..12917
                     /locus_tag="LP386_002456"
     CDS             11538..12917
                     /locus_tag="LP386_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL1919662.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            13198..13427
                     /locus_tag="LP386_002457"
                     /pseudo
     CDS             13198..13427
                     /locus_tag="LP386_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4483 a         2338 c         2924 g         3682 t
ORIGIN      
        1 gtaaatgttt tttgataaat agcggtctgc tgcgtctgga aaaatcgtaa cgacacgatg
       61 accaggtggt aaacgacgaa tttctcttaa tgctgctgca aaagccgcac cactcgaact
      121 tccaactaat agtccttgtt ctcgtgctaa ctgcctagta tagttaaacc cttctacatc
      181 agagattgtc tcgatctgat tgattgaaag gggagaaaga aacggcggaa tgaattctac
      241 accgataccc tcaatttcgt gaggggctgg atcaccacca tttaacacag agccctctgg
      301 ttctacaccg attattcgaa tgtcgggata tttttctttc aaaaaggtag aagttccagc
      361 aaaggttcca ccactcccaa ttcctgctac aaaactatgg atattttctt tgatttcatg
      421 aaagatttct ggccctaacg tatgatagta agcagcagga ttatctttat tttcaaattg
      481 aagaggcaga tagctgtttg atatctcctc tgcaagtttt ttacttttgc tgatggcacc
      541 gatgattcct tgctcactag gagaatggat gatctttgct cccaatgctt tcatcaattg
      601 ttgtttttct aagctaaact tctctggaac aacaaaaacc gttcttaatt tgtatgtgag
      661 tgcggccaga gcgatcccaa ttcctgtatt tccggcagtt ggttcgatga tcgtcgtttt
      721 ttcattgatt tttccttggg caaatccttc tttgatcaaa taactgccca atctatcttt
      781 gatacttcct ccaggattta aatattctag ttttgcataa atagcagaac ctttaggcat
      841 agaatagtgc tgattgtcaa agcgataaag cggtgtggaa ccaatagctt ctgtaattgt
      901 cgagataatc atgtgggcct cctaaaaaaa gataataaaa aaaggagctg actattaaat
      961 cagctccttg aaagacatag agaaaaattg agtagataaa aagataagtt acctggtact
     1021 cattctatga agggcaatta atagacatga caaatagtat gctgctttta tgcaccatac
     1081 aacagcaacg attcaattgt ttttggttgc tgactgtcat gtgtatccct ccaagtaaaa
     1141 tttttattaa cgatagcatg aaaaaaaata aaagtcaaag gcttgaaaga aaaaaatatt
     1201 tcgatagcat cgtttacccg tgtttatttt tctgacaaat aggcatgaga ccttaaaaga
     1261 tagagaatac tctagttttc tggccggttg tctgatacaa taaagttgat tatgataaag
     1321 aaaagaagga gcaaaaataa tgatctcagc aagtgattta agagccggta tgactttcgt
     1381 acaagacggc aaactgatta aagttctgga tgcaagccac cataaacctg gtaaaggaaa
     1441 tacagttatg cgtatgaaac tgaaagatgt ccgttcaggt gcaacatacg acacaacgtt
     1501 cagaccagaa gaaaaatttg aaaaagcaca tatcgacaca aaacctgtac aatatttgta
     1561 cacgatggat gatacagctt tcttcatgga tttggaaaca tatgagcaat atgaaattcc
     1621 tgtagaaaca gtagaagaag aaatgaaata tatcctagaa aacatggaag taaaaatcca
     1681 atttttcggt agcgaagtca tcggcgttca attaccaaca actgtcgtat tacgtgttgt
     1741 ggaaacacaa ccttccatca aaggtgcaac agtcactggt tcaggtaagc cagcgacaat
     1801 ggaaactggc ttagtagtca atgttcctga cttcatcgaa acagatgaat tgttggaaat
     1861 caatacagca gaaggttctt atgtaaaacg tgcgtcaaaa taattcgcta acggattgat
     1921 aagaatttga aaacagagct tgacctcttg aaaggcagat catcggatct gcctttcaag
     1981 aggttttttg tggaatcagc aaattgaaaa ataaaaaagt atttgatttt atttatattt
     2041 tgaaagatga atggcaaaag ctagagaaag aaaaaactgc acttatttat gaagaaattg
     2101 aaatgattca taaaattgaa aatatccgaa ctattccgaa ctatattgaa gcgaaaatat
     2161 tttttcatca ctaaatagtg ttgaatttat gtttttatgt ataaatagct tctaatagtt
     2221 cgggtatttt gtttttataa ccatttttat tcttattttt aaaaaaatat ttcgaaatat
     2281 actagacaat tcagaaaatt ttgtttaata ttattccaat aaaattcaaa tctttatcaa
     2341 atgaaattcc aataaaaacg gaaaaaaagt gaaaagagga atgaaaaaat gacagaattg
     2401 ataattggcg gagtcacagc aagcacattg gcagaaaagt ataagacacc tctgtatgtg
     2461 tatgatgaag aaaagatgag acaaacgatg ctgtcattca agcgaggctt tgtatcgaaa
     2521 cgttttgata caaaagtgct ttacgcctct aaagcattcc aaacgattga gatgctgcat
     2581 ttagttcgtg aatatggatt cgggctagat gttgtcagtg gtggggaaat ctataccgct
     2641 ttgcaagctg attttcctag agatactatc tacttccatg gtaacaacaa gacgccagag
     2701 gaactgatct atgcacttga aaatgatttg ttgcatattg ttgccgataa tttgatggaa
     2761 gttgaattat tagcagaatt aagccaacgc tatttaaaaa aaatctgtat catgcttcgg
     2821 ttgaatgtcg gagtagaagc acatactcat gaatatatcg tcactgcgca tattgattca
     2881 aaattcggca tgagctatga aagtaaagag tgccaacaag cccttcagtt gataaaagaa
     2941 agcagctatc tagagttaga aggatttcat gctcatatcg ggtcacaaat ttttgatgtt
     3001 actgcttggt tagctgaaat cgacaaattg acgaattact taaccgattt tgaccaacct
     3061 ctttccttga atcttggcgg agggtttggg attcgttata cacaaaatga tcagccgatc
     3121 ccagtcgaag aggcactaaa aaaactgatt gaatatacgg aagaagcttt ggaaaaacga
     3181 aaactgacca ttcgtcaatt actgatcgaa ccgggtagaa gtattgttgg agaagctggt
     3241 acaacactat acacgattgg tttcatcaaa aagacaccac ataaaaaata ttactttgta
     3301 gatggcggga tgacagataa tatccgtcca gctctgtatc aggcagaata cgattgtgat
     3361 ttagcagcaa aactgtcgga agaaaaaaca gagaaagtga cgattgcagg aaaaatgtgt
     3421 gaatcaggcg atgtggtaat taaagaagct tatttgccga aagcagaatc gggtgatctt
     3481 ttagctgttt attccacggg agcttatgga tactcgatga gcagcaacta caatcgagcg
     3541 acacgaccag cagttgtttt tgtcaataat ggccaatcaa gactgattgt tcgcagacaa
     3601 gcattttctg atctactaag gggggaagtt tcctatgatc cttcataaat ataatggctg
     3661 cggaaatgat tttatcttat tagattacgc agaagacaca gattatagtc aattagccgc
     3721 ttctttatgc acaaaagaaa aatatgatat agacggattg atcgccgtaa aaatcgatcc
     3781 gttggaaatg atctattaca acaaagatgg cagccgcgcg ccgatgtgcg gaaatggcat
     3841 tcgctgtttt gctcgatacg taaatgatca gaacatgatg aatgaacagg aattcaacgt
     3901 agagacatta gcaggcacaa gaaaaattac ggtgttggat ccctcacctt tttattgcag
     3961 cgtagatatg ggagtgccag atgattctcc ggaaaaaatc aaagctaatc aaacttatcc
     4021 aataaaaaac caggaaatag agatcaatgg tgaaaaagta acgatcacta gtttattttt
     4081 aggaacgatt cataccgttg tttttgttga aaatgcgcgt gaggaagtct ggagaaaaag
     4141 aggtgaactg atctgtcatc atcctttgtt caaagaaaaa accaatgtca actttgtaga
     4201 agtagtcaat gaacaagaat tgatcgtccg tacctatgaa agaggagtag gttggacact
     4261 tgcttgcggt acaggttgct gtgcctctta tgtggttgct aaggaaactg ggaaaatttc
     4321 agcagatcag gtagttgttc acttggaaca aggagacttg atgatctctg gtgaggatgc
     4381 gatacaaatg gctggcccag cagttcatga atggacaaga atattggagg aatgaagatg
     4441 ataaaaggtt cgatcgtggc gctgatcacg ccgatgaatg aagagggatc agtagattat
     4501 gctggtttgg aaaaattgat ccaattccat ttagatgaac aaacagatgg attattagtt
     4561 ttaggtacaa caggagaatc ttctacgctc acacaatctg aggaggagca gatccttcaa
     4621 ctgacagtaa agaaagtggc tggccgtgtg ccggtgattg caggagctgg aacgaataat
     4681 acgaaagaaa cgattgaaaa agcgaagcat tttgcttctt tgggggcaga cgcacttttg
     4741 gtcatcaccc cttactacaa caaaacaagt gatgcaggac tagctgctca ttttacagca
     4801 attgcagaag cctcaccgat tccgcttatt ttgtataatg ttccttctag aacaggcatg
     4861 tcgattccaa tccatgtatt agtaaattta gcagaacatc ctaatatcat tggtttgaaa
     4921 gaagcctcag gagatatggc ttatgtgatg gatgccgctc ggttgattgg agaagaattc
     4981 ttcctttaca gtggaaatga tgatttgatc ctaccagtaa tgagtgtagg aggaagcggt
     5041 gtaataagtg tatgggcgaa tatccaacct aaaatagtcc atgaattagt aaaagatacg
     5101 caggacggaa gatggcagca agcaaaagaa aagcaattaa atgcacttga actgatccat
     5161 gccttgttca gtgagaccaa tcctattcct gtcaaagcag ccatgtcatt attagactta
     5221 ccttccggac ctctacgcct gcctttagtt tctctttcaa aagagaaaaa gaaacaatta
     5281 gctcagcttt tgttaaaaga aaggacggtt gaaaaatgaa aatcggactg attggcagtg
     5341 gacagatggg aaatagagtc gaagaagttg cacaagaaag aggagatacg gtccttcttt
     5401 tacggacggc acctaaagaa gcaactacgc ttgcttttac ggaactgcca gaactgctta
     5461 ttgatttttc tcatccagat aatttagaga aaatcctttc gtatagctta tcatatcaac
     5521 ttccgttagt cattggcacg acaggttata cacaatcaca gttccaagaa ataaaagaac
     5581 atgccaaaca tgtacctgtg atgtatagtg ctaatttttc gttcggcatc atggtgatga
     5641 atcaactaat caagcaagca gctgcaatgt tgcaaggctg gcagatcgaa ctgattgaaa
     5701 aacatcatag tcgtaaaaaa gatgcaccat ctggtactgc aaatatgctg cttcaaacaa
     5761 tccaagaagt gcaaaagctg cagcccgtat acaactggca agggaaaaaa agagaagaaa
     5821 accaaattgg tgtacacagt attcgtgcag gttctttacc tggtgaacat gatgtattgt
     5881 ttgctgctac tgatgaaata tttacgatca aacatgaatc tttttctaat cgaatctttg
     5941 ctgcaggcgc agtagaagca gcggactggt tgaaagatca gtcaccaggt tattacaaat
     6001 tagaagattt attaatggac aaaggggtgt aaaaaacgtg gaagctcaag aaatcatccg
     6061 ctacattcaa acggcatcta aaaagacgcc tgtgaaagtc tatctgaatg taaccgagcc
     6121 aatcgaattt aaagaaagta aagtttttgg tgaaggaagc agcttcgttg tttttggtga
     6181 ctatgagacg attgctccgg ttttagaagc tgaatcagaa aaaatcattg aaatcgaaat
     6241 cgaaactgct gcaagataca gcgcagttcc tttgctagat attaaaaaaa ttaatgctcg
     6301 tatcgaacca ggtgctatta tcagagatca agtgtcaatc ggcaacaatg ccgtgatcat
     6361 gatgggagcg attatcaata ttggtgcagt aatcggtgaa aacacgatga ttgatatggg
     6421 tgctgtctta ggtggacgag cgacagtggg caaaaactgc catattggtg caggagctgt
     6481 cttagcaggt gtgatcgaac cagcatcggc caaaccggtt atcgtagaag acggcgtact
     6541 ggtaggtgcg aatgcagtga ttgttgaagg tgtccatatc ggaaaagatg cagtcgtggc
     6601 agcaggagca gtggttttag aagatgtggc agcagaaact gttgtcggtg gaatacctgc
     6661 acgtgtatta aaaataagtg atgatcagac aaaagaaaat acagcattga ttgctgcgtt
     6721 acgcgaatta tagaggagat ggagaaaaat gcgcgaaata gatacctgta ttgtgggggc
     6781 aaccggatta gtcggccaaa cgatgctcaa agtgttagaa gaatatgatt ttccagtagg
     6841 acgattgaaa ttattagctt caaaacgttc agccggtaaa gtttgtgtat tcaagaaaaa
     6901 gaaacacact gtacaggaat tgacagaaac ttcatttgaa ggatatgatt tagcgctatt
     6961 ttctgcaggt gcttctgtat ccaaagagtt tgcgccaatc gcacgaagtc agggactatt
     7021 tgtcatagat aattcctcag catggcggga agattcggat attccattaa tcgttccaga
     7081 ggtcaatctg gaagactata cattgaatcg gctgattgca aatccaaatt gttcaaccat
     7141 tcaagcggta cttccgctta aagctttaca agaagccttt ggtatccagc gagtcaatta
     7201 ttcgacctat caagcagttt ctggttccgg gcaaaaaggc attgaagatc ttcatcgtac
     7261 gcaaaatgac gaggaaccag ttttgtatcc ttataatatt agccaaacgg tgattccgga
     7321 aatcgatcag cctttggaaa atgggtatac aaaagaagaa cagaaaatga taaatgagaa
     7381 ccgtaagatt ctgcatcagc ctgctttgcc agtatcagca acctgcgtac gtgtgccaat
     7441 cgaaaatgga catggagtct ctgtggcagt tcaactgcaa aaagagttta cgacggaaga
     7501 aattagagag tgtctcagcc agtttccagg gattcaatta gaagatgatc tagcagcaca
     7561 taaatatccg acgagcattc ttgctagagg aacagatatg gtttatgttg ggaggatcag
     7621 aaaagacact tctttagaga acggattgtt gttctatacg actgccgata acatacgcaa
     7681 aggagccgct gcgaatgccg tacagattgc tgcagcttta atgcagaaaa tagcggaggt
     7741 ggcaagatga gtaatacgct gaaagtagcg aaattcggcg gaacatcgat gtctcatgaa
     7801 gagcaattca aaaaagtccg tacaattgtt ctttcagatc ccaatcgcca agtgatcgtt
     7861 gtttctgctt taggcaaacg tacgtcagat gatgacaaag taacagactt actttatttg
     7921 atttatgctt accttcagca tcatgttgat tggacacccc tttggaaaag gatttgtgat
     7981 cgtttcattc aagtaagaga tgttcttgcc ctgcagttac ctattgaaga tgaactagca
     8041 cgcatacaga aacaactgga agacgaaaag ataactgaag attatttagt aagtagaggt
     8101 gaatatctga ctgctcaact gatggctgag tatcttggtt accagtttat tgacgcaaaa
     8161 gacctgattt tctttgacta tgatgggaaa atcgatcagg aaaaaacagc acaggaaatc
     8221 acaaaagcat ttaaaagata tccgaaaatg gttgttccag ggttttacgg ggcgaaccct
     8281 gcaggaaaag aaaaattatt gggccgtggg ggaagcgaca ttaccggcgc gatactggcg
     8341 aagatgttgc aagcggaaag ttatgagaat tggacggatg tttcaggaat catgatggct
     8401 gatccgcgaa tcatcgatca tcctaaaatc atcgaggaaa tctcttttag agaactgaga
     8461 gagatggctt atatgggggc taacgttctt catgaagcag ctgttttccc agttcaagag
     8521 gctgatatcc ccatccaaat aaaaaatacc aatgatcctt tcgctcaagg gacaaaaata
     8581 tcgaatcacg aaatagaaaa ggaaaatgga ctgacaggaa tagctggacg caaggatttt
     8641 ctttccatca ctttattcaa acgtcatatg tccgatgaaa tcgggtttat ctggaaagca
     8701 atgagcattt ttgctaaaca tgagatatca atcgaacata ttccttcagg gatcgacaat
     8761 atcggagtga tcgtctcagc agaagcgatt gccgataagt tatttctcat cacgaaagaa
     8821 ttaaaagaaa cacttggcgt ggaagaaatc gtcgtgatcg aagacttagc tttgatctct
     8881 gtcgttgggg gtccgcataa agaattgatt ggattatctg ggaaagtgtt atcgatattg
     8941 aacaaattag aaattcgcac atcgatctta tcacaaggag cacaggagtt gaatctgatc
     9001 atcggtgtac cgaataatca atatgaaaca gtagtgaagg gtatctatga agggatggtg
     9061 aatacggatg ctgaaagaat atcgaatggc actccatcaa attcctgaaa tcgggtttca
     9121 tgaattcaag acaaaaaaat atttatatga acaagtaaaa aacagcgagg ccgttatcca
     9181 tgaaatcggc gaaacaggac tactccttta ttttgataat cagcaagaag aaacgattgc
     9241 ttttcgaaca gatatcgatg cactgccagt caaagaagaa acgaatctct cttttgcttc
     9301 taagcatgaa ggttatatgc atgcatgtgg tcatgacgga catatggcga tgcttttagg
     9361 gttgactgac tttataacta aacacattga ggatcttatt tataatgtag tactgatcta
     9421 tcagccatca gaagaaattt ccggtggcgc acaaagcgtt attcagtcag gattgttgga
     9481 taaatatgaa gtacaagcaa tatttggctt tcatctatgg cctggactag ctaagggaga
     9541 agttttctct cgaccaggac ctttgatggc acaaagcagt gaaacagaca ttatcattaa
     9601 aggccagtct gcacatattg cttctagtga aaaaggaatc gatagtctgg aggcagctgt
     9661 acgatttttg aagaatgttt atgattttga ccggcaatta ccggcagagt ggaatcatct
     9721 aatgaaattt ggccaaatcc aaggtggaac gatccgaaat gttttagctg gagaagttat
     9781 tgtatccgga agtatccgtt cttacagttc agatatgcaa aattatttga agaggggatt
     9841 agaccattta gcagaacagt ttcactctac agctactatt tcttttcgct ataatgacgg
     9901 ctatccagct gtaatcaacc atagaggctt atatgcagca ctgttagatt caaacaaact
     9961 acatgaatta gatgctccag ttcttcaagc cgaagatttt ggcatatata cgcaacaata
    10021 tccatgtgta tttttctttt taggtgtcgg tgatacccct gctttacatg atccgacgtt
    10081 cgattttgat atggatgttt tagaaaatgg tgtagaatgg tacaaaacga ttctttttac
    10141 agaaaatctt cttgtaaaaa tcgatagcag ttcaaaagag gagcgagtaa ataatgatga
    10201 atttatccaa tcgatttagt cctaggcttt ctagaataga agtatcaaaa atacgacaat
    10261 tcgatcagca aatatcgtcg ataccagatg tgatcaaact caccctggga gaaccggatt
    10321 ttccaactcc tgaacatgtc aagcaagcag gaatagcagc gattgaagaa gacttttctc
    10381 actataccgg aatgagagga ttagaggaac tgcgggaagc ggcttgtata tttcagcaac
    10441 agcgttatgg attaacttat gatccgcaaa cggaagtttt gacgacagtt ggtgcaacgg
    10501 aagcgattgc ctctgcgttg ttatctgttt tggaagaagg agacaaggtt cttattccag
    10561 cgcctgctta ttcaggatat cagccattag tggaactagc tggtgctgaa ttgatcccga
    10621 tagatacttc tgacacaggg tttgtctgtc agccggaaca atttgaacga gcatttgaac
    10681 aatatggatc agctgtcaaa gcagtcattt taaactatcc taacaatcct actgggacga
    10741 cattgtctgc aaaacaattg aaagcaatcg ctgaggtttt aaaaaaatat ccggtatttg
    10801 ttataagtga tgaagtatat gctgaattga cttatagtgg aacgcatatg tccatagcta
    10861 cttatcttcc agaacaaaca atcgtgataa gcgggttatc caagtcacat gcgatgactg
    10921 gttggcgagt gggctttatt tttgctcaaa aagcccttat tgacgaacta attaaagtcc
    10981 atcaatatct ggtgactgcc gctacaacga tgtcgcaaaa agctgcggct gaagcgctaa
    11041 taaatggggt gaaagatagc gagaatatga aagagcaata tcaaacacga agagactatc
    11101 tggtccagca attggcgcct ttaggatttg aagtgaccca gccaaacggt gcattttact
    11161 tgttttgcaa actcccagct gccattcaaa ctgactcttg gcagttttgt gtagaattag
    11221 cggaacaggc aaaagttgcg tgtatcccag gaattgcatt tggcccagaa ggagaaggtt
    11281 atatccggat ttcttatgct agcagcatgg aaaaattaca tgaggcctgc aaacggatca
    11341 aagacttttt aacagaacag tgattcatag attttatcaa aaaaacaatc gttaattttg
    11401 cggtatattc tgcaaggaga cgattgtttt ttaaatttag ttcaaatgaa cgcgtttctt
    11461 ttgattcata actaatgtaa tgttaagttt aaattgttta gaatgatttt aaaagaatat
    11521 tcaaggaggt ttcatcaatg gaaaaaatca aagttgtcat tgtaggtgca tctcatggag
    11581 ggcatcaatc gatcttggaa ctattgacac gatacggtga aaatgtagat atcacgctat
    11641 ttgaagcagg agactatatt tccttcatgt catgtggtat ggagctgtat ttagaagaca
    11701 aggtaacaga tgtaaatgat gtacgtaatt tcagaccaga aaactttccg caatccaatg
    11761 ttcatatttt aaataatcac gaagtaaaaa cgatcgatgc cgataaaaaa acagtaacgg
    11821 ttactagcgc atcagataac gaaacaaaag aatatcctta tgacaaattg attttgagtt
    11881 ctggtgtcaa accaaacaat ctgccagtac caggagcaga tctagaaaat gtctacttga
    11941 tgcgtggata caattgggca accaaaatca aagaaaaatt aaatgatccg gctattaaaa
    12001 aaatcgctgt cgtaggtgcg ggttacattg ggatcgaagc agcagaagca agccgaaaag
    12061 ctgggaaaga agtcgtattg cttgatgtga tcgatagacc tttaggcact tatttagatg
    12121 ctgagatgac agatatttta gaacaacacc taaatgaaaa cggtattgaa gttttgacaa
    12181 atgcaaaaat cgaagctttt actggtaacg gaaaagttga ggcaatcaaa acaagtgaaa
    12241 aagaaatccc agcagatcta gtcattcaag ctgccggtgt gaaggcaaat acagaatggt
    12301 taaaagggat cgtcgactta gatgaacgtg gctggatcca aacaaatgaa tacttgcaaa
    12361 cgaatcttcc agatgtgtat gcagtaggag atgctacact tgcttattct atcccagcac
    12421 gcaaaaaaat gccgatcgct ttagcgactg ttgcacgtag agaagcacgt tatgtagtaa
    12481 aacatctttt tgaagaagta ccaaacaaac cgttcggcgg agtcgtaggt tcctctgcat
    12541 taagtgtctt tgactatcat tttgcagcaa gcggattgaa tagctttaca gcagcaaaag
    12601 caggagtaga tgtacgagtg tcttattatg aagatacgtt acgaccaaaa tatgtaccag
    12661 aagaacaagg aaatccaaaa gtgtccatcc aattattctc ggatccaatg acccatcaat
    12721 tgctaggagg agcagtatta tctacctatg atgttacagg tcaaggaaat gtattggcac
    12781 tagcgatcca aaacaaactg actttagaag aactagcaga agctgacttc ttcttccagc
    12841 caggctttga ccgacaatgg agcatgttga atctagccgc tcaacaagcg ttaggagaag
    12901 aaccatttgt agaataagaa aacgaaatat ttgaaaagag gttgtgaaaa agctgccttg
    12961 catcaagtaa taagaacagc caagtaaaaa cagcttctta tgtttttaac ttggctggac
    13021 ttattaccgc agatgcaagc ttttgaacac cgtttatttt caaaaaaggg actgtgacac
    13081 gatttgtgta ccgaccccca aaagttagac caaaaaatct aacttttgga ggtcggtatt
    13141 ttttatggtt aaatatactt ttgaacttaa attaaagatc gttcatgatt atttggatgg
    13201 caaaggcgat tggaccgtaa aaatccagat caagagattg aagcggaaat gcttaaaatt
    13261 cgggagaagc acaaggatta tggctgttta cggatgacca atgaactaag aaaccgcggt
    13321 ttctctatca ataaaaagaa agttcagcgc ttgatcaaga agctaggaat aaaagtaacg
    13381 gcatacacgc gtaaatcacg tcgctacaat tcttatcgag gaaaagt
//
LOCUS       DAFEKH010000071        13346 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.074, whole genome shotgun sequence.
ACCESSION   DAFEKH010000071
VERSION     DAFEKH010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13346
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.074"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(45..1364)
                     /locus_tag="LP386_002458"
     CDS             complement(45..1364)
                     /locus_tag="LP386_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL1919663.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
     gene            complement(1361..2014)
                     /locus_tag="LP386_002459"
     CDS             complement(1361..2014)
                     /locus_tag="LP386_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1919664.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            2302..2822
                     /locus_tag="LP386_002460"
                     /pseudo
     CDS             2302..2822
                     /locus_tag="LP386_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2724..3440)
                     /locus_tag="LP386_002461"
     CDS             complement(2724..3440)
                     /locus_tag="LP386_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBL1919665.1"
                     /translation="MIKEKIDSFVTIDDLQVGKPDPEGYLLCLKRLRVEQAVVVEDSP
                     VGAQAAPHMTVDVQALDADFFAFSGHKMCGPTGIGVLYGKRQLLEQMEPVEFGGEMID
                     FVNLYDSSWKELPWKFEAGTPNIAGAIDYLNEIGMENIHRYEQELVAYVLPKLQAIGG
                     ITIYGPQDPEHHTGVVAFNLDGIHPRDVATALDMEGVAVRSGHHCAQRFIDDFCLTNW
                     SFKQSMIMPFERLQCRGIFE"
     gene            complement(3564..3749)
                     /locus_tag="LP386_002462"
     CDS             complement(3564..3749)
                     /locus_tag="LP386_002462"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919666.1"
                     /translation="MTKALIFDFDGTMIDSEWMFYESIHHYLLKPIYWSSSAIKFLLQ
                     TINKVLGRQQNCPFMKG"
     gene            3976..5249
                     /locus_tag="LP386_002463"
                     /pseudo
     CDS             3976..5249
                     /locus_tag="LP386_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(5356..6387)
                     /locus_tag="LP386_002464"
     CDS             complement(5356..6387)
                     /locus_tag="LP386_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1919667.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(6394..7224)
                     /locus_tag="LP386_002465"
     CDS             complement(6394..7224)
                     /locus_tag="LP386_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1919668.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(7221..8036)
                     /locus_tag="LP386_002466"
     CDS             complement(7221..8036)
                     /locus_tag="LP386_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBL1919669.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(8033..8857)
                     /locus_tag="LP386_002467"
     CDS             complement(8033..8857)
                     /locus_tag="LP386_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HBL1919670.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(8847..9947)
                     /locus_tag="LP386_002468"
     CDS             complement(8847..9947)
                     /locus_tag="LP386_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBL1919671.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            10125..10910
                     /locus_tag="LP386_002469"
     CDS             10125..10910
                     /locus_tag="LP386_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HBL1919672.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            10943..11326
                     /locus_tag="LP386_002470"
     CDS             10943..11326
                     /locus_tag="LP386_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBL1919673.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            11402..11533
                     /locus_tag="LP386_002471"
     CDS             11402..11533
                     /locus_tag="LP386_002471"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL1919674.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            11502..11738
                     /locus_tag="LP386_002472"
     CDS             11502..11738
                     /locus_tag="LP386_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL1919675.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            complement(11816..12787)
                     /locus_tag="LP386_002473"
     CDS             complement(11816..12787)
                     /locus_tag="LP386_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBL1919676.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
BASE COUNT         4055 a         2912 c         2307 g         4072 t
ORIGIN      
        1 ataagtctct atttttcaat aactattgca aaattatatc ttaattaaga aaatattttt
       61 attttaaaga taaaaaattc ttcatcctgc aatactttat attctatatt gtaattattc
      121 agaatattac ttacaatata taaacctaat ccattactat tttccttatt taaatcaaat
      181 ttaacatcaa atattttatc catattcgaa attttattgt taccgtatga attctctata
      241 tataaccaat cattaactat cccaatatta attaccccat ttacatcagt atattttacc
      301 gcattactaa tcaaattaga tagaataatc tttaaagctg tttttcctat ataaacattc
      361 tcgtctaata tataattatt gacagttatt ttcttttgat ttgctaatat ttcatacttt
      421 tttaatatgt cttctaatgt atcatttatt ttcaaatatt cttcatcatt attcaaattt
      481 tctatagaat gaactgataa tatttgagaa atattttttg ttaaactatc aacgatttca
      541 atacattcat taatataaat atctctttct ttatattttc caatattgta tttcatgttt
      601 tccagtatta ttttaagact agcaagaggg gttttaagtt catgggatgc acctttaaaa
      661 aagtcatatt ttaacttttc taattttaaa atttctttat ttttaaattc caaatcgtca
      721 attgttctta ataaagtaga atacaaatca ttaatttgtt gttttaattc tccaacttca
      781 tcattagagc taacttttaa actcattttt ttatcaagtt tcatcatttt atcagtaaca
      841 atttttattt cttgtatatt attttttatt gattttgcat aaattaaaga aataatagca
      901 gaaaataaaa ttgatattaa taaagaatat ggtaaaaatt taaggcttaa atctttcgca
      961 tctttttgca tatcagctgt agaaacaaat tgtagatttg tttttttacc atcattaagc
     1021 tttatttctc tttcttcaat tatcaaagaa ttactatcac tttctaaatt aacatttata
     1081 ttatctttga tttgtatttc attcttatta tttttttctt ttatgaatac ttttatttca
     1141 ctactcttgg aataaaactc caaagtttgt tctatatatt ttatttcttt tccattcata
     1201 ttactagaaa tttcatttgc catattatga atcttttctt ttctcgtctc caaatatgtt
     1261 ttaggaaaga taaaaaaaat taatgaatga actaatataa ttattattcc aagaacagaa
     1321 aatatttgta tgaacatttt tggaaatatc tttaattttt tcattttctc tccaatttat
     1381 atcctacatt tcttatagta gttatacagt ctaattgtaa tttttttcta agttctttta
     1441 tatatacatc tattactcga tcataaggag tttcttcgct atctttccat acataatcaa
     1501 taatttgcat tcttgttaac acttgtccat tattatccaa taaacatttt aatacttcta
     1561 gttcttttgc atttacatct atttcttcac catttatttt agctgtatag ctattaaaat
     1621 taaccgatag atccttatat tcaaacttct ctaaatgtcc ataattcttc ttaattaaag
     1681 aatctattct agcttttaag accggcaatg aaaatggctt ttctacatat ccgtctacta
     1741 aattagtaaa tgcatcaatt ttatattctt catcactaaa tgcagtcaag attagaattg
     1801 gtaaattgct tttctttcta atttctttca acacttctaa accatttata aaaggtatct
     1861 gaatgtctaa gataaccaaa tttatatcgc tattaaattt tgacaaggct tctcttccat
     1921 ctttagcttg aataacagta tatccaaatt ctgaaagata ttcacttatt ccctctctta
     1981 tcatattatc atcttcaaca gttaatattt tcatatatac ctccacttaa gcctatacac
     2041 tagatattat acagcatatt atggctctat aatatctagt gttggtgacg ccttctgttg
     2101 ccaatacttt ttcttttttt taataaatgc aaacagacac cttgaaatcc tttagaaaaa
     2161 aggcttctat aatattttgt gttgttggaa aatcgaaggc gattttctac taacactttt
     2221 tcttcgtttc aactcaaaaa gagactcact tttggtaaaa tttagtcgac caaaacatca
     2281 ccctaccaaa ggagtcgctc tatggataat catactagaa aattactcgg attaacagat
     2341 aaacatttat tttttgatga agaatggctg attgaaaaag aatataaagg cgttcaagcg
     2401 cagtttatta aagggagatt ggatgacgca ccttcccatt gtgaacactg tggatcgatt
     2461 cgtattatcc gcaacggttc ctatacgaca cgtactcaga tgttgaaagt caaagaaaag
     2521 ttgactattt tagaattaaa acgtacccgt tttctatgct atgattgtgg gcagaccttt
     2581 tctgcgaaaa cggacttagt tgatgaacat catcaactaa caaaggaact gaagcaggcg
     2641 attctcatag aactgtacga aaatcaatca cgtaatctga aaatcagaag aagtaccgtc
     2701 ggctcaagcg atattggaaa ctcttactca aagattccac gacattggag ccgctcaaac
     2761 ggcattatca tcgactgttt aaacgaccaa ttagtcaaac agaaatcgtc gatgaaccgt
     2821 tgtgcacaat ggtgtcctga acgtacagcg acaccttcca tatccagagc agtcgccaca
     2881 tcacggggat ggatgccatc caaattaaaa gcaaccacgc cagtatgatg ttcaggatct
     2941 tgcggtccgt aaatggtgat accgccgatc gcttgtaatt taggtaaaac gtaggcaacc
     3001 agttcttgct cataacgatg aatattctcc ataccaatct cattcaagta atcgattgct
     3061 cctgcaatgt tcggagtacc agcttcaaat ttccatggca gctctttcca tgaactatcg
     3121 taaagattga caaaatctat catttcaccg ccgaattcga ctggctccat ttgttctaac
     3181 aattgacgtt tgccatataa tacaccgatt cctgtcggcc cgcacatttt atgcccgcta
     3241 aaggcgaaaa aatctgcatc caacgcttgt acatcaactg tcatatgcgg tgctgcttgg
     3301 gcaccgactg gactatcctc aactacaaca gcctgttcaa ccctcagccg tttcaagcac
     3361 aacaaataac cttctggatc tggtttgccg acctgaagat catcgatcgt cacaaaggaa
     3421 tcaatttttt ccttaatcat cggatgtgct tcaaaaaaat agtctagctc ccgcagttca
     3481 gaattgagac tactccgatt ttccagtgct gctgatccgc tgctcaaaat gttcagcatc
     3541 cactggtctc ccaaccgctt gacttatccc ttcataaaag gacagttctg ctgccgtccc
     3601 aacaccttgt tgatagtctg caaaaggaat tttatagccg aactgctcca gtaaataggc
     3661 ttcagtaaat agtgatgaat actctcgtaa aacatccatt cactgtcaat catcgtccca
     3721 tcaaaatcaa aaataagtgc tttggtcatc ttctttcccc cttacccaaa acaagcaaaa
     3781 gctgtgtcct gctctctcta cagtatcagc ataaaaactg ccgtctgaaa agtcaaaggt
     3841 gaaagaaatg tggcgctata atttctagga ctgatagtaa atcattctat cagtcctttt
     3901 gagcataaaa aaacaaaaca tacagaagct ccgttagaat tgaatcacca caacacaatc
     3961 aaaggagcgt tctgtatgcc tgatcttcat cttatcaaac tattactagg aatcaaagat
     4021 ggaaacattc aaatcactca tgtcgagaag aaaaaaatac attcaatcaa cagtatcgtt
     4081 gtttctgcca cgctcattaa aacgattcag ccctgtcctc agtgtaaaca ggtgaatcaa
     4141 catgggctga tcgttaagaa cggaaagaaa aaatcgctgg tccttctcaa taagtgtgcg
     4201 aatcaacgga cttatcttgc tttggcaaag caacggtacc tctgtcgtgg ctgtcacacc
     4261 tattttacgg cgaataccta cattgttgaa aaaaactgtt ttatcgccaa acaagtacat
     4321 tataaaatat tggaggaatt gactgaaaaa caagcaatga cgacgatttc taaacattgc
     4381 ggcgtttctt ggtcaaccgt ttcgcgaaca ctcgcttctc tgctccccat gacaaacgtg
     4441 aaaataaatt ggttgcctcg ctgttcattg gtagatgaat ttcgttcatt gaaaaatcaa
     4501 gtcggtccct attctttttc ttgtatggat ggcgatactg ggaaattact ggatattctt
     4561 ccttcacgta agaagaaaga tctcatttct tattttatgc aatttgaacg acgtgcacgt
     4621 ttaaacgtaa aaatactcgt aacagatatg aacgcctctt atgctttgct gataaaagag
     4681 tgctttcctc atgccaaact cgttgtggat cgctttcaca tcgtcaagca cctcattcgc
     4741 agttttaagg atatttgact atgagtcatg aaaagcttcg accgaaacga tccaatacaa
     4801 gccaaacact atcgacaagt gaaggcttta tctcgacttc tgatcaaacg acaggacacg
     4861 cttgtttatg ataaatggac aaaatggcgt aattttggtt gggcctattt aaccgaaagt
     4921 gaagtcgtag aacgtctact ttctacttct gatgaactac gaatagctta tgcttactat
     4981 caagaaattc ttcaagcttt ttatgacaaa gaagcggaca tcttctttca gcttgtaaaa
     5041 acaatgccca agtcggttcc aagagaactg catcatataa aaaaagcgtt tataaactat
     5101 gaatccggca ttcgtttagc cttagagttg ccttactcaa atggcaaaat agaaaatctg
     5161 catacccaca tcaaagcatt gaaacgaata gcttacgggt taggatgaga accagaattt
     5221 tcttaatcaa tcatctgatc acttattaaa cataaaaaaa catctaaagc agaaaatcaa
     5281 ttctacctta gatgttctta tatcactcta tcagtcctat ttgacaaaga gccagaaatg
     5341 tttgccgact atacactagc tttgttgtgc aaaatgctga gtatcaattt ccacagggat
     5401 tgctagaata tctttcagct gaatgtataa ggcatcgcta attttctctt cccgatcgtt
     5461 caaccgatcc actaaaattt ctttgccctc cagcgtttga aaaacatacc gttgaatgtt
     5521 gcctaaaata aatgattcct tccatagaac cggaatctta accccctgag gaaccggttc
     5581 aaattgaatc agctccggtc ttaaataata aatgcagcga ttgcccttag cggaaaactc
     5641 gtgggtatac tgattcagct cataccattc gaaacgatta tagttgccga taaattccgc
     5701 aacaaatcgg ctctgaggat tctgatacaa ttccttcgag gtggaaacct gagccacccg
     5761 cccagcttcc atcacaaaaa tccgatcact gattcgcatc gcctcttctt ggtcatgagt
     5821 cacaaaaatc atcgtcatcc ctagcgattg ctggatagcg cgcaaatccc gctgcagctg
     5881 ttttctaatt cgggcatcca aagcacttaa tggctcatcc agcagcagga ctttcggttc
     5941 agtgaccaat gagcgagcca gtgccacccg ttgtcgttga ccgccagaaa gaaactggac
     6001 atttttatct gcctgctccg tcatatccac caatgatagc atctcaaaaa ccttttcctg
     6061 aatcacctca ggactcagct tctttacctt caaaccaaag gctacatttt caaaaacagt
     6121 catagttgga aacaatgcat actgttgaaa aacaaagccg atattgcgat ccttcgtagg
     6181 cttatcggca atattctcat tgtccagcac aatctcaccg ctctttggtt gttccaatcc
     6241 cgtgatacag cgcagcaacg tagactttcc gcacccgctg ggacctagta aagtaaccag
     6301 ctcacccttt tcaatctgaa tttcatcaat agctaaaatc tgtttttcat caaaaaacag
     6361 attgagatca tgtatttcta aaaacatttt ccgtcacaac tcctttaagg gcttcttttt
     6421 cgactgcttc tcttccctcg tctgcttaag ggacagctgt tgcttttgtc gataagtcag
     6481 cataaaggta gttaaagcaa ttcccaccat aaacagcaaa tacaaaacca tcacagcgct
     6541 agccaaatgg ccgttttcgt tcatccgccg cagcatatag atgcgtaccg tctgaaatcg
     6601 accgccaatc aacaggttcg tcagcatgta ctccccaaaa accgaagaaa aaatcatcag
     6661 agaaactagg gtcacaccga tacggatgtt tggaaacagc acctggataa taatcgtaga
     6721 catcggggcg cccaaggttt ctgctgcatc cactaattcc ttcagattaa ttaagcgcat
     6781 ctggttgtta agactaagat agacaatcgg caacgccgta ataaacaatg cacctaccaa
     6841 cactacaaac attgggatac cagtttcagc atacgttcga agcaaagccg ttaccaaaat
     6901 cactcctggt aaagcatacg gcagcaggag cagcttttcc agccaacgat tcaaacgagg
     6961 gaaatacaaa tgaatccaaa taatggtggg aatcatcaac aacagaatcg tcaccaagac
     7021 cacacctgct aataaaagtg agcgacccac cgcagcaata aattccctgt ccgtcagcag
     7081 ctgttggaac cattgcaagg taaaatcact aggtaaaagc gattttgacc atttagtgga
     7141 gctggcatac aaaatcgttc caataatcgg cagcaagtaa tacaggacaa agcagaacaa
     7201 aatcggtttt attaactttt tcacgtctgc accaccttgc ctttcttttg aataatcaac
     7261 attgccgtta ccagcaggac acctaaagcg actgccaacg cactgcctaa attaggcttg
     7321 gcgaacacat ctcccgacac taaagccgca attcgaatcg ttaaaagatt tacattactg
     7381 ctggtcaggg catacgctgt ttcataggtc cccatgccat tagcaaataa gatgacaaag
     7441 gtgctggcaa tcgatggtcg caaaaaaggc aaagccacct tgaaccaagc atacgctgat
     7501 gaagcgccca gcaattgtgc ggactccagc cattcctttt tcacttcctt catgctggga
     7561 tacaaaaaca agacccctaa cggaatttgg aaataggtat acgtgatggt caatccccac
     7621 caagaataca aattgaagtc cgctagaaat ggcaaaatca ttttcagcac acctacattc
     7681 cccaacaaaa taataaaaga gaatgccagc ggaatcccag caaaattagc tgccaaattg
     7741 gaaacaaagg tgattttctc ctgcaattta gtcgatagat tcattaagca taaacataaa
     7801 ataaacgtcc cgattaaccc aatcacactg gagctgacag caatcagtac gctgttaaca
     7861 aaggcctgtg tgtaatattt gttgctgaaa atatcactgt aattggccaa tgtccactgg
     7921 ttagttaaat cactgtgcaa gctgcacaga accataaaaa gcagcggcag cagtaaaaat
     7981 gcacagaaga taaaggaggc aggaaccaga accaagcgtt ttttcatctc tttcatcccc
     8041 tcatcaattc ttgaatgtcc tgcattttct ctgacggtgc aattcctaat aaccagcaaa
     8101 acaatggagc cgccagcagc tgtggtacag tttgttcctt cagcttttgg cgtttatttg
     8161 aaatcaaata aaaaggaact tcacgatgtg cagccaagct gccgccatgc agtccgtgcg
     8221 catccatccc gtgatccgca gtcaccacga cttgataacc tttttgcagc cattcaggaa
     8281 ggtaaatagc caataatctg tccgcctgat taaccgctgc tgcatattca tgagaatcgg
     8341 cggtaaattt gtgaccgaca tcatcaatat tcatcgaatg tacgaccaaa aagtctggct
     8401 gatactgatt cactaaataa tgggcatccg caaataaatg cgaatcaggg taagtgtcct
     8461 cactataaaa gatgccatgc tgaatcagtc gctcctcctg atgctggatg cgatcaacca
     8521 aacgattata gggggcttga ttgtacaact cgctgtacca gtggtaagcg gcggctcctg
     8581 tttttccgcc agcttcctta actaattcaa acagcgacca ctctttggat cgctgagcat
     8641 ggtaattact atagatgcca ttttcatagg ctggaacgcc ggtcatcagt acttcgtata
     8701 acggacgtga attgctgggc agctcacttt ttaccttcaa taagcttgct tgctggtgct
     8761 caactaaatg attcatgaac ccaagctggg cgacggctgt gtcgtagcga cagccgtcta
     8821 gtataactac aatcagtttg tcaagtctac tttgcatagg tcagtacctc cgcctgccaa
     8881 agctctggaa gctctacaga ggtcttgttc caagcttcat tgtcttcaac tggcaccgcc
     8941 gcttcataag catcctccgg cagtaatttt tcagctactt ctttaggcag ctctaccttg
     9001 cgaataggtc gcgcatagcc ctttgccaaa ttgatttgcc cttcatcaga taaaatatat
     9061 tcccgtgcta gctttgccgc attgggatga ggggcatttt tattgattaa ggttgtatac
     9121 ccgctaatga tggagccgtc tgttggcaca gttacctcaa aacgctcgga gtcaatttgg
     9181 tcacgataat ttagtccatt gaagtcccaa acaactgcca catcgatttc acctttttca
     9241 agatttgcta cgctggcatc aacggtggac aaacggcctt tttctgccat ttttttgtag
     9301 taattcagac ctggctgaat atccttttcg tcacctccgt tggcaatcgc cgcagccaat
     9361 acagcaaatt gtgcttggtt ggcaatcgtc acatccccca cgctaacttg atagtcaccc
     9421 tcttgcagct ccttccagct agtcggtgct tgcttcacat tctctttatc ggtgataaag
     9481 gaaatggttc ccgtatagct taacaaccaa tccccatcat catcctttgc ccaatccgga
     9541 atttcctccc aatagttggt cttataaggt aaggttaact ctttgctttc agccaacgga
     9601 ccgaagctga taccgacatc accaatatcg gcggttccat tttttccttc tgattcaaac
     9661 ttagccaatt cttctgcact ggacatatcc gtatccacgt gacttaagcc gtattctttt
     9721 tcaaggtcgt tccaagtgcc tacccaattt gcccaagtat ccggcattcc caagctggca
     9781 atctctcctt cttccttggc tttttctata atcgtatcta aagagtcgtc tgccgcagcc
     9841 gattgcttcg ttgcttcacc tgagccgcag cctgtcagca ggatacttac tgttgctgca
     9901 caaaataaac cgatagtcat gttacgaatt ttttcattca ttttcattca ttcttctccc
     9961 ctttcgataa ttccattcta acaaagcttt gtaatgagag aatcagtttc ttgaaaaggt
    10021 ttcatgaaca atgtaaaggt tgtatatggt ttgtaaattt cgacgaattc ccgttaacct
    10081 tctaaagctt ttgcggtatg atagtagaaa aaaggaggct ccctatgcag tattatgatc
    10141 agcatctcca cacgtatttt tcctttgatt cagaggaaaa atttgaaaac tatttagcct
    10201 atcagccgga gtttttcgtt tctacggatc actttgattt aaacaatcca tctaccggaa
    10261 aagatgacat tccggattat ccagcctata taaacaaact ggactcttta aaagaaacct
    10321 attccaccaa atttctgcga ggtatcgaga ttggcgttgt tccaggacaa gaagagcgga
    10381 tcgtggatta cctcgctcag catccttatg atttaaagct ggtaagtatt catcaaaatg
    10441 gccgctttga ttatatggac gatgtggttt taaccaaaga tcccattcaa actaccaagg
    10501 aatattttga tcagatgttg caggtcttga cggattttcc agaaggagat attttgactc
    10561 actttgatta tggattacgc cgcttcacct tcacagcgga agaattcgcg gagcattttg
    10621 aggctcagct gctaacgatt ttcaaaaagg ttgttgaacg agaattggcg atggagttaa
    10681 atgccaagag cttcttgaaa tacggcaacg aagaccttta ccgttatgcc gttcctttgt
    10741 atcaaagtgt cggcggaaag ctctttacct taggctcgga tgctcatgtt gccgaagatt
    10801 atcagctggg ctttaaaaaa atgagtcagc tgttggcaga ctgtcaggta gaaaagttgc
    10861 tagtcattca aggaaaagaa cgccgcctga cgccgctgcc gattttgtga ttcctatata
    10921 atagaagaaa gtggtgaaaa aaatgagcaa cctgtgggac tacaatcaag aggcacccat
    10981 ccattattta attgcgcgac attgggatgc gttgaaaatt gaggcggttt gccgatcctt
    11041 gttagcagcc gttccaaaac aacaactgga aaattttttg gtggctgaca gcttgcagcg
    11101 ggaaaaagtt caggcttatt ttgcagcctt taaagatcag cctttggaat atttgcatgc
    11161 gcagtttcat cttttttatc aagtagccgc cccagatgac tacaacgatt tacgaggaca
    11221 gctgcaattg acctttcaag cggatgaaac cgcctatacc gttttattgg gaatggctcg
    11281 ccttggtgat caggcgaagg tcgagtggcg gattttcgat atttgatggc aggatcaagg
    11341 cgtttcagtt gcaaaccttc ctctctttca attagaaaaa ccgcagcagg aagaagtttg
    11401 tgtgctggtc accgatgctg gtgaaattcg tctccgctta tttcctgacc aagctcccct
    11461 ggctgtagcc aactggcgct ccctagctga gcaaggcgtt tatgacaaca cacctttcgg
    11521 ctcgtgtcat taaggaattt gttattcaag gtggcgcttt ggatggttct ggtgatgaag
    11581 ctgtttccag ctatgagggc tttttcgctg atgaagtgca tcgcggactt tatcatttta
    11641 atggcgcctt ggccttaggg gaccacggcc cccacaccaa cggcaaccag ttttttattg
    11701 tgcaaaacac aaaggcgcag gctgacctgc taatgtaaag caagcatact tggagcttgg
    11761 aggactaccg gagctggatg gtcgttatac tgtttttgga caggtatacc aagggttaga
    11821 aatcgtagca gcgatcgcag ctcagccgac aaacagtgaa gatgtaccga ttgagccagt
    11881 gttcattcga caaattaact tcgaaaaaac atcgtaaaaa gacactcact gacttcagca
    11941 aaagctctat tcttgagctg gctgcagcta gtgagtgtct ttcatttatc cataagataa
    12001 agcttggatt caataaataa ataaatgttt tggttaaagc tgtgaccagc aaatgaggaa
    12061 ccgtgcgagc cagttgatct gccaatgcaa acatttcttt aggtgaaggc gctggcgtgt
    12121 ctgccaacgg atactccagt cccaatgctt ggtaaccgtg cataccatag cagtggtacg
    12181 gtagtaattc taacggtacg aaccgatcaa gatctgccac aaaacaagca atcgtcagca
    12241 gctcggtcag gttcatattg atacctggaa ccacaggaac tcgaattcgc acttcgcagt
    12301 taggatactc aattaaaaag cgacgaatat tcttcaaaat ttgttggtta tctaagccgg
    12361 tccattgttt gtggagcttg ctggtaaaca tttttacatc cacaaacaat gtatccacat
    12421 agggagctac cttttggatt tcattataag caccacaaaa gctggtttcc agtacggtat
    12481 tgattccaat gtatttcgat ttttgcaaaa tttctttagc aaaatccgcc tgaaccagtg
    12541 cctcgcctcc gctaatggtc actccgccat ccgagtgaaa gtaaaaaaca gcatccttct
    12601 caatctcatc cattacctct tcagcggtca tggtctggcc aaatcctttt tcaatctgct
    12661 tgctttgtga ttcgggaatc gaacaccagg cacagcgtaa tgggcagccc tttaaataaa
    12721 caacggtccg taaaccagca ccatcatgta gagaaccctg ttctattctt aatactgttc
    12781 cttccatata gatttttgaa ttacacacta gtttaaacta aaacacacaa ggaaaaactt
    12841 accatttaat cataaaatta gctcatataa atatactagg atgtaaaata gactggtcaa
    12901 aatctggtca aaaaagagga ctaatacagg tagtcctctt ttttgttatt ttaatattct
    12961 aaatcatttt ttattggttt attcccttat tcgatgtaga ctcaaatcac tatatcacta
    13021 gatatcaaac ggcgtcatac ggaatcaaaa acatcaaatt tgacctgtta aatggtcatt
    13081 gaataacatt caaaatcaat aaaacggagt cagacacgga gtcaaaaacg ctgagagtaa
    13141 aaaatatata cagccttgta ggtaaagtac cacagggctg tatatttttt atttcagatt
    13201 accttaaatg attccattta ctttttatct cattttttcc tactagttag tatcaaatac
    13261 tctcctattt tctcaataaa ctatttttgg atacatggta tctgaaacag ctaaaacctt
    13321 gtcattacag caaaaaatca cgttat
//
LOCUS       DAFEKH010000072        13145 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.075, whole genome shotgun sequence.
ACCESSION   DAFEKH010000072
VERSION     DAFEKH010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13145
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.075"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(77..149)
                     /locus_tag="LP386_002474"
     tRNA            complement(77..149)
                     /locus_tag="LP386_002474"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Lys,seq:ctt)
     gene            530..1099
                     /locus_tag="LP386_002475"
     CDS             530..1099
                     /locus_tag="LP386_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HBL1919677.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1086..1946
                     /locus_tag="LP386_002476"
     CDS             1086..1946
                     /locus_tag="LP386_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBL1919678.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2136..2840
                     /locus_tag="LP386_002477"
     CDS             2136..2840
                     /locus_tag="LP386_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1919679.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2845..4680
                     /gene="walK"
                     /locus_tag="LP386_002478"
     CDS             2845..4680
                     /gene="walK"
                     /locus_tag="LP386_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HBL1919680.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4677..5993
                     /locus_tag="LP386_002479"
     CDS             4677..5993
                     /locus_tag="LP386_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919681.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5994..6863
                     /locus_tag="LP386_002480"
     CDS             5994..6863
                     /locus_tag="LP386_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HBL1919682.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6918..7727
                     /locus_tag="LP386_002481"
     CDS             6918..7727
                     /locus_tag="LP386_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBL1919683.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7830..8459)
                     /locus_tag="LP386_002482"
     CDS             complement(7830..8459)
                     /locus_tag="LP386_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HBL1919684.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8629..9921
                     /locus_tag="LP386_002483"
     CDS             8629..9921
                     /locus_tag="LP386_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL1919685.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9997..10659)
                     /locus_tag="LP386_002484"
     CDS             complement(9997..10659)
                     /locus_tag="LP386_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBL1919686.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10884..11168
                     /gene="groES"
                     /locus_tag="LP386_002485"
     CDS             10884..11168
                     /gene="groES"
                     /locus_tag="LP386_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HBL1919687.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11219..12844
                     /gene="groL"
                     /locus_tag="LP386_002486"
     CDS             11219..12844
                     /gene="groL"
                     /locus_tag="LP386_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HBL1919688.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4369 a         2264 c         2833 g         3679 t
ORIGIN      
        1 taaaaaaaga acagcgtaaa tgttttcgaa atgctttcgc accaacattt acctgttccg
       61 tgggtttggc acccaatggg ccgtgagggg ctcgaacccg cgacccgctg attaagagtc
      121 agctgctcta ccaactgagc taacggcccg tacaaaaagt acttaataat agtagcacta
      181 agaattttaa aatgcaagac tacatttaaa gaaaatcaga aaaatcttta cttccttata
      241 ggaaatcatt catagattat tcacatttgc tcgctattat ataagcatac caacaaacaa
      301 agttcttgca agagaacaaa ccctaacact tttttcattt tttactcctt tcccgccgtc
      361 tccccggcgg gtctcctgtt cttaacgata aaagacaaga aggcttagcc ttcttgtttt
      421 ttgttttcat ggaatcccgc taatcaaatc acctagttaa agcaactaga ttgaatgttt
      481 atcataagtc tgatatcatg tttatgaaat gaaaaaagga gcggttatga tggaaaaaat
      541 gcgtcagcaa ttaatggagt gggggaagga actagaaaca ttccgtctgc ctcactggga
      601 agaactccct gacttagaac tttatatgga ccaagtcaga acgttagttg atcgttatct
      661 ttcacctgtg atacaaggag aaaagcatcc attgcttacc tcttctatgg taaacaatta
      721 cgttaaacta ggtttgatac cagcaccagt taaaaaaaga tataacaaag aacacgtagc
      781 atttttactt gcaatcacta cgttgaaaca agtattgact attcctgaaa tcaaagaagg
      841 gatattgttc caaggaaaaa cagtaggaat tcgtgaagcc tataatctat tttgcgatga
      901 acaagaagca gctgtgtgga tggtcagcca attagcacaa ggtaaatctc atccgcaaaa
      961 attcgaccag gcaacccctg tagaatatat tgctgtaaga gcggcaactt tatcgtttgc
     1021 aatgaaactt cttgcggaaa aaacgattgt tctagaaacc gaatatttaa aagaggagaa
     1081 aacaaatgaa aaacaataaa atcgcaattt tagtagattc aggtacggat gtgccagaag
     1141 aattgataaa aaaatacgag atgtatatga tcccattgaa aattatttat aaagatcagg
     1201 tatatacaga taaaattgac attacctctg aagagatcta tcaacgtttg ccagaggaaa
     1261 tccctggtac atctttgccg gatggtgagt cgatcacaga aatctttgag caaatcaaaa
     1321 aagacggtta tgaaaaggta cttgcggtaa caatttccag tggattgagc gggacatata
     1381 atgtggttcg tttaattgca caacagcaag aagaattgga agcatatgta ctagatacga
     1441 aaaatattgg tattggtgca ggtttttctg cgatccaagc agcaaaatgg ctggaagaag
     1501 gagtagaatg ggatcaactg atcagtaatc tgaatgagtt agtcgaaaga acaaaagttt
     1561 tctttaatgt tgcgacattg gaatatcttc aaaaaggtgg acggatcggt ttagttgctt
     1621 ctattgtagg aaccgcttta aagcttaacc caatcatctc atgtaatgaa gaagggattt
     1681 attacacagt aggaaaagct aggggacgta aaaaaagttt ggataaaacg gttgcttacg
     1741 tcaaagaaaa aatcggtaat gcaaaggtct tcaacttagc tgttgcccat ggggatgcga
     1801 aagaagaagc aattgaaatg gaagcgagac ttaaaagaga gttcccacaa gcaaaccaaa
     1861 tctactttgg ccagatttct ccggcattag tagtccacac tggtccggga ttattgggtg
     1921 tcggtgtaca agttttagaa ggataaatca aaaaaaggaa acactgaggt gaaaatcagt
     1981 gttttccttt tttattgaag ttagaacaaa aaataataaa gtattttgca ctttcatttt
     2041 aattttctct tttgttttat aggcaaagat gaaacaaaag cagaaatacg gtataatgag
     2101 aaggtatgac aataatatat aagaggtggc tctttatgaa aaaagtttta gttgtcgatg
     2161 atgagaagcc gatttcggat atcgtcaaat tcaatttagc caaagaaggc tatgatgttt
     2221 atactgcata tgatggggaa gaagccttgg aaaaagttgc tgaggtagaa cctgatttga
     2281 ttttacttga tttgatgcta cctaaaatgg acggcttaga agttgctcgt gaggtacgca
     2341 aaacttatga tatgccgatc attatggtaa cagccaaaga ttctgaaatt gataaagtcc
     2401 taggcttaga gttaggcgcc gatgattacg tgaccaagcc attttccaac cgagaattag
     2461 ttgcacgtgt caaagcaaat cttcgtcgcg gtgccacggc tgcgaaggaa ccagaagagg
     2521 cagcacctgc ggaattgacg attggtgatt tgacgatcca tccagaagct tacatggtga
     2581 cgaaacgagg agaaacaatc gagttaacac atcgtgaatt cgaactactc ttttacttgg
     2641 cgaagcacct tggacaagtg atgacaagag aacatttatt acaaacggtt tggggttatg
     2701 attattttgg agatgtacga acagtggatg taactgtacg tcgtttgcgt gaaaagatcg
     2761 aagataatcc aagccatcca aattatttag tgacacgtcg tggtgtcggt tactatttgc
     2821 gtaacccaga acaggagtaa ttggatgaaa agaaaagtcc gcttttttcg atcagtcaat
     2881 tttaagatcg ctattacctt tattctgatt ttattgatct cgatcgaaat tattggtgcc
     2941 tactttatac gtggtttaga acgttccacg atcaatacat ttattaaaga tatgaatcaa
     3001 acggtggaat cattagcaac aacaatcagc ccggaattga atcgaaaaga taatgcagat
     3061 gatgaagagg taaatgcgaa tatcaaaaga tttattgaaa acagtgcgac tagcgatatc
     3121 atcgaaatac gggtcgttga cgaaaaaggg atcatccgag gaacaaccga tgtcaatgaa
     3181 caaagcgctg tgggaaagaa aaatgattat gttgatatca atgatttcac gactaaacgt
     3241 tatgttgctt tagataacga cgataaacgg gtgaatatca atgttcaacc gatcctgtcc
     3301 ccgaccggcg atgccgttat cggggctctt tacgtcaaaa gtaatatcga acaaaaatat
     3361 tcggaaatca ataacacagc agtcattttc tttactgcct cactaattgc ggcatttatt
     3421 tcaatgatcg tatctgtttt agttgctcgt tcgattacac agccgatcgg tgaaatgaga
     3481 gaacaagcca ttcgaatcgc tagaggagac tacagtcgga aagtcaaagt gcatggacaa
     3541 gatgaacttg gacagctggc tgataccttc aatcagttag ctgaacgtat tgaagaagct
     3601 caagatacaa tggaagctga acgcaatcgt ttggatagcg tgctatccca tatgacagac
     3661 ggcgtcattg cgacagatcg caggggtaaa gtcattacga tcaatgatat ggctgtttcc
     3721 ttgctagata tcaaaaacga ggaagcaatc ggacaatcga ttttgacact tttagatatc
     3781 gaagaagaat atacgttgcg gaaattatta gaagatccaa acgaaatggt acttgaccgt
     3841 tcaaccagta cattggaaag tgatcagatg atcttgcgag tagacttttc tatgatccgt
     3901 cgcgaatcag gttttatcag cggattagta gctgtcttgc atgatgtgac agaacaagaa
     3961 aaaacagaac gggaacgtcg tgaattcgtc tctaatgttt cccatgaact tcgtacaccg
     4021 ttgacaagta tgcgtagtta tatcgaagca ttgagcgaag gtgcgtggaa agacgaggaa
     4081 gtagcaccaa attttttgaa ggtaacgcta gatgaaacag accgaatgat tcgaatgatc
     4141 aatgacctct taaatctatc tcgcatggat acaggtaata cccagcttca attagaatat
     4201 gtcaatttca acgagttagt gaattttgtt cttgaccggt ttgatatgat ggtgggaaat
     4261 caggaaaaaa attataagat ccgtcgtgaa tttacgcaaa gagatctttg ggtcgaagta
     4321 gatacagata aaatcatcca agtagtcgat aatatcatga ataacgcgat caagtattca
     4381 ccagatgggg gaacgattac ttgtcgctta ttagaaacgc ataataacgt ggttttaagt
     4441 atcaccgatc aaggattggg gattcctaaa aaagatctga accgagtgtt cgagcggttc
     4501 tatcgagtag ataaagcacg tgcaagagca caaggtggga caggacttgg attagctatt
     4561 tctagagaag tgattaaggc gcatcgaggc gctatttggg cagagagcaa ggaaggaaaa
     4621 gggtcgactt tttatatctc gctgccatat gaaccttatg aggaggaatg gtgggaatga
     4681 gaatctctga aaaagtcgtt cgtataggac tcattttgat ggttgcgtta agcatatact
     4741 tctcttatgc aatctggctg agcccagcag gaaaaagttc aatcaacgta gatgagacaa
     4801 acactcaaat gatcgagtct caaagcaatc gaaaaacttc cgaagtcttt cttccgcttc
     4861 atgttacatg gcaccattcg ggaatgatcc aagaaaccaa cagtgaaaat ctcgtgtacc
     4921 gattgcaatt gatcatcgat aaagcaagat ttggaaagct ttctgaagta gtttcaggag
     4981 acaaatcaca gtttgaacag gtgaaaaatc tgaactctgg ttttgagttg gcctataatg
     5041 cgcctttttt gctaagagaa tacaaggaag catttgattt agatttagat gtgtcgaact
     5101 tggcaaaaga aagcgaaaat atgtatttta ctagaataca attcgatcaa ggaaataaaa
     5161 aaatccgatt tttgaattat tcgaaccatc tcgtatatga agcaaatatt tcgttgaatt
     5221 ggacagatat caataaagaa ttaacagcaa aagacacaaa atggacagaa atgacaacag
     5281 aaccatcgac gatcgacacg caatatgcta cgaaacattc gatcaaactg aaaaagtata
     5341 gttatatcct gtcacagcaa ccctatacac tttttagaaa tgcttttttc cagaaaccag
     5401 atagcgtgaa aaataatgat gaaagcaatg aattgatttt ttacggtggg aatgaaacaa
     5461 tgtctatcca ttcggaaacg caagtagttg attttcgtgg agagctgcca gagaaaaaag
     5521 aaaatgctag tgtattttct gaaagtttcc cctatattag caaattaggc agttctttag
     5581 ggaacctcag atattttgac cgcagtgaca atacgatcga ttatcggata ttcgtggaag
     5641 gcttcccggt ttttgggaca gacagcagag gacagattgg tgtggaagtt ggcggtgaaa
     5701 cgaatggttc tgtgcaagtg aatatccaaa ccagtttgaa tacgattcaa gtgccgatac
     5761 cttcagacga agaagtagaa cttgcaagta cgaatgaaat catccagcag ttaaaagcta
     5821 agggagcaga tagcaacaag attggttcag tgatcgttgg ctatacatgg caaaatgtca
     5881 aagaaacgaa tcgtgtcgtt gatctcttac ctgaatggta tgtgaaatat aaagataact
     5941 ggtattcagc taacgacctt ctggaaaaat tacctggatt ggaggcgaat taattggatt
     6001 tcaaaaaaat cgaatggata tttttcgtcg cttttttagg gttgaatgtg tttttattca
     6061 gcagttatca tgacgcggta taccaagaaa acaatgtcat tcgctctaat cagactgaat
     6121 caatccaaca acgtctggct agcgacgata tcacttacac ggggaagatt tcgtctgaga
     6181 acaagcaagg ctattatctt agcgcggagc agaccaatct tagcacttca ttagcgaatt
     6241 atcgcaaggc tggtaaaagc ggcttgctgg caagtggtgt gtttttagac ggtgatgttt
     6301 tgacgaaatc tttatccagt tcagatgctg aaaagaacgt gatcgatcca gataaaatta
     6361 gtagttcctt ggaagatttt ttatctaaca aagacaatat tttattcggt aatgattatg
     6421 tgtacacgaa aaacttttct catttagaag aagaaccact agaaatccaa gcaagccaag
     6481 agtatgaagg catcccattc aatgatgata cagcaaaaat cgttctttct ttagaaaaaa
     6541 acgataatga ttatagcatc acgaaataca tgcagacgca tttatctgat atcgagcagc
     6601 tgcgcgaaaa gacggaactg tatacggaag aggaagcaat caatacattg tacatcaata
     6661 acaaaatacc aagaggatca aaaattttat ggcgtcagct agcttattcc tgtattctga
     6721 aagtccggga aaaaaatgtg tatgttcctg tttggcatgt agcgatcgaa acaagcgata
     6781 aagtggtcca aattgagagt gtcaacgctt tcagcaatac gatcgtgaca aacaatactg
     6841 taccaaaagt ggaagatcaa taaaaaagcg agtataatga aaaaagttta caaagtaaga
     6901 agggaagtag gagtcaaatg gctgaagaaa aaccagcttt taaaatcagt atcctagcaa
     6961 gtggaagttc gggtaattca ctttatatcg aaagtgaaaa aaaacggctt ttggtcgatg
     7021 caggacttag cggtaaaaaa atcacttcct tgatggctca aattgatcgg acaccggacc
     7081 aattagatgg aatacttgtg acgcatgaac atcgagatca tatacatggc gtgggtgtct
     7141 tggctcgtaa gtatcatttg gatgtttttg ccaatcagca gacttgggaa gcgatggaac
     7201 cactgattgg aaatgtacca gtggaacaaa aacatctatt tgagatgggg aaagtcagaa
     7261 cattcggcga tatcgatatt gagagtttcg gcgtctccca tgacgcagcg gctccgcaat
     7321 tttatcgttt ccataaagaa aatcggtcat tcgtcatgtt gacggacacc ggatattgca
     7381 gtgattatat gcgaggtgtc attgaaaatg ccgatggtta tttgatggaa agtaatcatg
     7441 atcttgagat gttacgcatg ggaccttatc cgtggaattt aaaacagcgt attttaggag
     7501 atagaggaca tctttccaac gaagacggtg cacttgtcat gactgatgtg atcggtaatc
     7561 ggaccaaacg aatctatctt ggccatctta gcaaggaaaa caatatgaaa gaacttgctc
     7621 atttaacaat ggaaaatgtt ttgaaagaaa aagattttgg cgttggacat gattttgaaa
     7681 tctatgatac agatccagat gaagcaactg agctattttc gatttaaaca gttcaatcaa
     7741 taaaaatata aaaagcagaa gataaaatca atcagggttg gttttatctt ctatttttat
     7801 ttttttagca tattaaaaaa ataaccgtat tatcgactga ctacactgat gtgctgcttt
     7861 tcatgtttct catccagtat ctcatctact aatgcaatcg cgtaatctgc catgctgatc
     7921 gtactgtcgc cagcagcgtt tctttgtaaa taatcatcac ttaacaaata agtacctgta
     7981 cgtttgccat gtggatcaaa taaagaagct ggactgatat aagtccaatg tagattttta
     8041 gattgtttca attttaacaa tccttcgtac atattgaaag ctgttggata gaagggtgca
     8101 tttttaggta cttggtcaat catacgagtc gtcttttctg tatctaagaa taacgaagag
     8161 gcacccccaa cgacaattaa gcgtgtatcg gttccttcaa gcatctcaat caaatgggac
     8221 aaagaagttt gatgcatttc ttcttttcct ttgggagcgt tgaaagcatc aacgacaaca
     8281 tcaaaagatg caagatcagt agttgtcaac tcaaataaat ccttttgtat aaacggaaca
     8341 tctgatggca atttttctgg atgacgcacg attgccgtca cgtctaaatc tctggacaat
     8401 gcttcgtcta aaataaatga acctgcatgg ccagtagctc caatgagtgc aattttcata
     8461 aaaaacctcc ttttttattc ctgtccattg taagcagttg ctgaatattc gtcaaagaat
     8521 ccgatttttg aaaagctcag tgcgcattcc tttcatggtt cgtgatcatt gggtatagtt
     8581 aaattaagaa aactgattga taaaaataga agttgaagga gataagaaat gaaagagtgg
     8641 ttagatcgtg cctttttacc aatgataaca tctgttgtga atcttagacc cttaactgct
     8701 ttgcgtaatg gaatgactta cacgatccca ataattattg ttggctcgct gtttttctta
     8761 tttgctcatt ttcctgtgga ttacatcgct cagtggatag acaaaacagg attttctatg
     8821 tattttacac aagtatacca ggctacattt gatgtgatag ccttttggat cgtttttgcc
     8881 attgcatacg cttatgcaaa agaagaagac atcgatcgct taccagtcgg cataacagcc
     8941 ttgtctgctt atctactgct tattcagcca ctaaatactc agatagatac tgtctggaca
     9001 ggtgctgaag ggatactagg agcagttaca actgggctca tcatcggatg gggctatgca
     9061 cgtttagtaa gacttgcgaa agggtggaag caaagagaga agatacctga aaatgtttgg
     9121 cagtctttta cttcattgat tccaatcatt gttatagtca cttttacgct tatcggttca
     9181 gcggtttttc aacagttgtt cagaatgact gttgttcaag gagtatggac atatgtccag
     9241 cttcccattc aatcgttcat agacacgttg tttggtgtgc ttttattagg tttttttgtt
     9301 ccgtttttat ggttatttgg tcttcatgga tctgcgatgg tcaatgggtt ggttagtccc
     9361 gtcttgcaag cgaattcatt agcgaatgca gaaatcttag cctcaggaca agagttgacg
     9421 gtggcaaatg gcggacatat cgttactcag caatttctcg atcagttcat gacggttacg
     9481 ggtgctggat tgacgttagg ggctgtattt tttatgacgg tttttgcgaa atcgaagaaa
     9541 tacagagaat taggaaatct tgctctttta ccagcctttt tcaacatcaa tgaatcaatt
     9601 attttttcca caccgatcgt gatgaacccg atgatggctg ttccttttat tttcgcaccg
     9661 gtcgtttcag gattgattac ctattccgct ttatattttg gattcgttcc tttatttaca
     9721 gcagtccaag tcccttggac aacaccgccg atcctctcgg gtttcttagt aggcggagtg
     9781 cctgcagcga ttttacaagg tatcgtgttg tcaattagtt ttttcattta tttcccattt
     9841 ttgaaaaaaa tagattctgc aaactgcaaa aaggaaagac agacaaaaaa tgatggagca
     9901 gcagaaaaga tgaacgacta aaaaacaaaa atactcctgt cgctttagat tgggaaaatc
     9961 accaatctag gatgacagga gtatttatag tcatgtttat actagccctt tttggacagc
    10021 taattgaaca agaacaacta atgtgttcat tcctacgtgt gtgatcatcg atgtccagat
    10081 ccgaccagtt gctttgtact ctaggctgaa gaagaaacct aggaaaaagt agattagcag
    10141 atgaccatca ttatgagcaa acgcaaacag caaagagctg atcactgctc cgacccaaaa
    10201 atttgaatat cgactgatga tccccagtat actgcggcgg aatacgaact cttccatgat
    10261 gggtccagca acagttgtcg ccaaaataaa agcgggtgct tccatgatca tctggatgat
    10321 attttgtgta ttctcggaag gggttgcttt gccaaacaat acagattcta acatgacagc
    10381 gatgctttgc agaatcaatg cgacaaagat tccaaccaat ccataaataa caatctttgg
    10441 agcagaagct ttttttaccg ctgattcgat cgctaagggt tcacgttgct taaaataaaa
    10501 aatagctagg acaacggcgc ctagtatata catgactgca gttgctgtga tcaattcaga
    10561 cgtagatttt acaagtccta tcgaagctag gatcaagggt gagataaaaa ttagaccata
    10621 gcaaaaaatg ctgaggaagc tatatttttt taaagacatg taattcctcc ttttaaggga
    10681 taacaagcat gcaaggcaag cttatatcga ttgatttcaa ttatatcata atttcaataa
    10741 gcagctgtca gaataaaatt tcttttcttt gatttaaaag cttgcaaaaa agagggagaa
    10801 tgagtattat taaaaatgta ggttagcact cgaaggttaa gagtgctaac agattaaaaa
    10861 aagagttatc ggagggattt atcgtgttaa aaccattagg tgatcgcgtc attatcgaag
    10921 tcgcaaaaga agaagaaaaa actgtcggag gaatcgtttt agcttctgct gctaaagaga
    10981 aaccccaaac tgggacagtt gttgcagtcg gtgaaggccg tttgttagaa aacggtgaaa
    11041 aagttcctgc cgctgtaaaa gcaggcgacc aagttatgtt cgaaaaatac gccggtacag
    11101 aagtaaaata cgaaggaaaa gaatatctga tcgtcgcagg aaaagatatc atggcgattg
    11161 ttgagtaaat ttggaagata aaaaaataat caaaaataat caatgaggtg aatcaatcat
    11221 ggcaaaagaa ttgaaatttg cagaagacgc acgcgcagct atgttacgcg gggtagataa
    11281 attagcagat acagtgaaag taacattagg acctaaaggc cgaaatgtcg tactagaaaa
    11341 atcttacggc tctccattga tcacaaatga tggtgtgacg atcgcaaaag aaatcgaatt
    11401 agaagatcat tttgaaaaca tgggtgcaaa acttgtatca gaagtagcat caaaaacaaa
    11461 tgatattgca ggagacggta caacgacagc aactgttctg acacaagcaa tcgttcgcga
    11521 aggtttaaaa aacgtaactg caggtgctaa tcctctaggc attcgtcgcg ggatcgaatt
    11581 ggcaacaaaa gcagcagtcg aagaattgca taatatctca actgttgttg attcaaaaga
    11641 agccattgca caagtagcag ctgtttcttc gggttctgat aaagttggac atttgattgc
    11701 tgatgcaatg gaaaaagttg gaaacgacgg tgtcatcaca atcgaagaat caaaagggat
    11761 cgaaacagaa ctagatgttg tagaaggtat gcagtttgat cgtggttact tatcacaata
    11821 tatggtaaca gataacgaca aaatggaagc tgttctagaa aacccatata tcttgatcac
    11881 agacaaaaaa atctctaaca tccaagatat tctgccattg ttagaacaaa tcttgcaaca
    11941 atcacgtcca ttgttgatta ttgctgacga tgtagatggt gaagcattgc caactcttgt
    12001 attgaacaaa atccgtggaa cattcaacgt agtagctgta aaagctcctg gtttcggcga
    12061 tcgtcgtaaa gcaatgcttg aagatatcgc tattttgaca ggtggtacag taattactga
    12121 cgatctaggt ttagaattga aagatgtaac aatcgaaaac ttaggaaatg cttctaaagt
    12181 tgttgtagat aaagacaata caacgatcgt agaaggttct ggagaaaaag aagcaatcga
    12241 agctcgtgtg caattgatca aaaaccaaat tgctgaaaca acttctgatt ttgaccgcga
    12301 aaaattacaa gaacgcttag ctaaattagc aggtggtgta gctgttgtta aagttggtgc
    12361 agctactgaa acagaattga aagaattaaa attacgcatt gaagatgcat tgaatgctac
    12421 acgtgccgca gtagaagaag gaatggtctc aggtggtggt acagctctag tgaacgttat
    12481 cagcaaagtt tctgctgtag aagcagaagg agacgtggca acaggtatca agatcgttgt
    12541 tcgtgcttta gaagaaccaa ttcgtcaaat cgctgaaaac gctggttatg aaggatcagt
    12601 gattgttgat aaattgaaga acgtggaact aggcactggt ttcaatgctg ctactggaga
    12661 atgggtaaac atggttgaag caggtatcgt agacccaact aaagtaacac gttctgcctt
    12721 gcaaaatgcc gcttccgttt ctgccttgtt attaacgaca gaagcagtcg ttgcagataa
    12781 accagaacca gcagcgccag cagctcctgc aatggatcca tcaatgatgg gcggtatgat
    12841 gtaagaaaaa gcaacttgct tatctacaac tgatcattag tgaaagacag ataaaaagag
    12901 gctggaacag aagcgtttaa ctccaagaaa taagaagaaa ttcacggaaa ttgcttttca
    12961 aatttttgtg aatttcagct tatttccgaa ggagttgctt ctgcttccgc tgtttatacg
    13021 tgtttagagc gtgagacaaa agtgttcttt acttttgtcc cacgctcttt tttgtgtgta
    13081 attataatga aaatagttat ttttaatagt tataatattt tatctattaa aagtaaatat
    13141 ccatt
//
LOCUS       DAFEKH010000073        12660 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.076, whole genome shotgun sequence.
ACCESSION   DAFEKH010000073
VERSION     DAFEKH010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12660
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.076"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            270..539
                     /gene="rpsN"
                     /locus_tag="LP386_002487"
     CDS             270..539
                     /gene="rpsN"
                     /locus_tag="LP386_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBL1919689.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            554..733
                     /gene="rpmF"
                     /locus_tag="LP386_002488"
     CDS             554..733
                     /gene="rpmF"
                     /locus_tag="LP386_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBL1919690.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            765..1142
                     /locus_tag="LP386_002489"
     CDS             765..1142
                     /locus_tag="LP386_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919691.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            1163..1312
                     /gene="rpmG"
                     /locus_tag="LP386_002490"
     CDS             1163..1312
                     /gene="rpmG"
                     /locus_tag="LP386_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBL1919692.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            1336..2319
                     /locus_tag="LP386_002491"
     CDS             1336..2319
                     /locus_tag="LP386_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HBL1919693.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            2349..2471
                     /locus_tag="LP386_002492"
     CDS             2349..2471
                     /locus_tag="LP386_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBL1919694.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            2489..4012
                     /locus_tag="LP386_002493"
     CDS             2489..4012
                     /locus_tag="LP386_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HBL1919695.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIIGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNEMHNWPTFYPASLSKHEIAQEMMAH"
     gene            4036..4275
                     /locus_tag="LP386_002494"
     CDS             4036..4275
                     /locus_tag="LP386_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1919696.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(4468..4929)
                     /locus_tag="LP386_002495"
     CDS             complement(4468..4929)
                     /locus_tag="LP386_002495"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL1919697.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(5124..5342)
                     /locus_tag="LP386_002496"
     CDS             complement(5124..5342)
                     /locus_tag="LP386_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1919698.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            5460..7076
                     /locus_tag="LP386_002497"
     CDS             5460..7076
                     /locus_tag="LP386_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBL1919699.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            complement(7317..8657)
                     /locus_tag="LP386_002498"
                     /pseudo
     CDS             complement(7317..8657)
                     /locus_tag="LP386_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(8933..9088)
                     /locus_tag="LP386_002499"
     CDS             complement(8933..9088)
                     /locus_tag="LP386_002499"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HBL1919700.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            complement(9384..9716)
                     /locus_tag="LP386_002500"
     CDS             complement(9384..9716)
                     /locus_tag="LP386_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1919701.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRLAISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            complement(10230..10421)
                     /locus_tag="LP386_002501"
     CDS             complement(10230..10421)
                     /locus_tag="LP386_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1919702.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            complement(10515..10901)
                     /locus_tag="LP386_002502"
     CDS             complement(10515..10901)
                     /locus_tag="LP386_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBL1919703.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            11595..>12660
                     /locus_tag="LP386_002503"
     CDS             11595..>12660
                     /locus_tag="LP386_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HBL1919704.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFNMIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKDFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHKPLIEYTENLSKI
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYCQWRNKNAVLWRFKN"
BASE COUNT         4263 a         1930 c         2398 g         4069 t
ORIGIN      
        1 aaaagctact taaaacggta tttgtgtttg attggactaa taaaagtgaa ttcttatttt
       61 tcagagccta aactgcatat tcttttaaat gatttgatta tctctatgta ccgataaatt
      121 cgttttcaaa tagttatcta ttcatatgag ttttatttca tgttatttat tgttgacaag
      181 agcaactctt gttgataaag tatcagtgtc aaaacgtaac gattacgatt tgaggtgtct
      241 aaatcaaaat aaaaggagta taaaggtata tggcaaaaaa gtcgaaaatt gctaaagcaa
      301 agaaacaaat ggcgatgatt gaaaagtatg cagataaacg tcaggaatta aaagccgcag
      361 gagatcgcac cgctctcgct aaattgccaa gagattcaaa tccgaatcgt ctgaggcttc
      421 gtgatcagac ggatggtcgt ccaagagggt atatgcgaaa gttcggtatg tcccgtatta
      481 agtttagaga acttgcccat caagggttga ttcctggagt aaaaaaagca agttggtaaa
      541 aggaggaaat atcatggcag taccagcaag aaaaacatct aaggcgaaga aacggttaag
      601 aagaactcat caaactgtag taaaaccaga aatttcattt gacgaagcga atggtgatta
      661 tagacgtagc catcatgtat ctttaaaagg gtactataat ggaaagaaag taattaaagg
      721 agcttcaaaa tagtttaata tataactttt aggagggaat caaaatggaa attatttacc
      781 cacctttagt tgaagaagga ttaaagtatt atcttgaaac gacccagcaa tcgctagata
      841 aatgcacttt ttatcgttcg atggtagaga gaggaattat tactgaaacg ggtttaccga
      901 cccaacaggc aattgaaaat ggattagtca aagattacta tgaggaccaa ggcttatcat
      961 ttgatgattt tttaagaatc tatccaattt ttgaagagta tgacgaggag ttatttcaat
     1021 gtatcgatgg ttattgggag atacctgttg atatgaaaga aaatttagtt tcacaattgg
     1081 aatctggcga gttaactttt gaagatgcac aacaaattca agcatatctt gaagatcgat
     1141 aagtattgaa ggaggaagat ttatgcgtca aaatattatt ttggaatgtg tcgaaactgg
     1201 agaacgtctg tatctcacca gcaaaaataa acggaataac cctgaacggt tagaattaaa
     1261 aaagtattcg ccaaaattgc gcagacgggc aatttttaaa gaagtgaaat agctaagtgg
     1321 taaaaaggtg acaaaatggg cataccagtt acaatcgttt ctgggttttt aggggctgga
     1381 aaaacaacgc taatcaatca agccttgcaa gtctcaccct accccaggga agaaattatt
     1441 ataattgaaa atgagtttgg tgaagttggg attgatcaca aattattagt tcatagcgag
     1501 gaacgggtgt tacaactaaa taatggatgt atgtgttgca gtcttcgcag tgatttatta
     1561 gcaatattga tttctttact ggaaacaata gaagaacatc aacaaccaat ttcacaaatc
     1621 atcattgaaa ctacaggtat agcagatccc caaccaatca ttcaaacact tttaacagcg
     1681 cctcaactaa gaggaagagt atatatcgat agtttattga ctgttattga tagtgacagt
     1741 tttgaactta ttgaaagaga accacaagcc cttaagcaac ttgtcatggc agatcgcatt
     1801 tttgtgtcta gaaaacaaaa cttgaattta tctgcactaa aaaaattaca gagagaaatc
     1861 aaaagtatta accctttatc cgatattcga atgttcacac atagtgaaac gattcaaaaa
     1921 aaggattttt ataatttgaa aaaatttaat catcccttag tttttgaaag tgattcatca
     1981 gaaaatcact ataatggcaa atactatcat caacaccatc aagtacatga gtttaaatca
     2041 attctcttaa cttcagatca agacataaaa aaagattttt tactccaatg gattgactgg
     2101 ctgattttaa ccaaccaagg gagcctgtat cgttttaaag gattgattgc tttacaagag
     2161 caggatttta tagttgccat gcaagaggta aacgaacagg ttaattttca atacaccact
     2221 cgacaaaaag accaaaccac tattattcta atcggaaaaa tgttggatga agaaaggatc
     2281 aaacagagtt ttgataaatt actggcggaa agcaaataat gataagtagt gattgggggt
     2341 aatttctaat ggagaaaacg gatatatcta gtgcatatcg acgacttaaa agcccgaata
     2401 ttaaaactag aaaaagggca ttaaaaatta tcaaagaaca taaacgaaat aaaatgaaga
     2461 aattagcata attaaggaag gaaaaagaat gaagaaaatc agtgtaggac ttattgggat
     2521 agcagctcta ggattattgg gagcttgctc cagcactaat gatgcaaaag tatcgaatga
     2581 taaagatgga aaattagaaa ttgtaacaac attctatcca atgtatgatt tcaccaaaaa
     2641 catcatcggc gatgaagcga acgtggattt aatggttcca gcgggatcag aacctcatga
     2701 ctatgagccc tcagctaagg atatggcaaa agctcatgat gctgatgttt ttgtatatca
     2761 taacgaaaac atggaatcat gggtaccaaa agctaaagaa agttggaaga aagctgggcc
     2821 taatgtagta gaaggaacaa aagacatgat tttattgcca ggtagtgaag aagaagatca
     2881 tgatcacgga gaagaagatc accatcatga actagatcct catacgtggg tttcacccaa
     2941 aatggcaatt aaggaagttt caaatatcaa ggatcagtta gttaaattgt atccgaaaaa
     3001 agcaaaagta tttgagacaa atgctgaaaa gtatttgact aaactgaaac ggttggatgc
     3061 tgactatacc actagtctta aagaagcgaa acaaaaaagt tttgtgacgc aacacgcagc
     3121 ctttggatat ttagctttgg attatggatt gaaacaagtt cctattgctg gactaagtcc
     3181 tgaagaagag ccatcttctg gtcgattagc tgaattaaaa gagtatgtta aaaaaaataa
     3241 gatcaattat atttactttg aaaagaatgc taatgataaa attgcaaaaa ctttggccaa
     3301 cgaagctggg ataaaattgg aagtactgaa tcctcttgaa agtcttacaa aagaacaaat
     3361 ggataatggt gaagattatg tttcagtaat ggaagacaat ctaaaagcgt tagaaaaaac
     3421 aactatggtt gctggtgaag aggtagttcc agaaaaagaa gcgaaggatg aaaagacagt
     3481 tgctaatggg tactttaaag atgccgatgt gaaggatcgc gaattgagtg attatacagg
     3541 cgaatggcaa tctgtttatc cgttgttaaa agatggaatt ttggatgaag ttttcgatta
     3601 caaagcaaaa atcaataaag acatgacagc tgccgagtac aaagattatt atactactgg
     3661 ctataagaca gatattgata ctatcaacat taaagacaac accattgatt ttgtagtcaa
     3721 cggtgaacat catcaataca catacaaata tgttggatac aaaattttga attatgaaaa
     3781 aggaaaccgt ggtgttcgtt ttaattttga aactgatgat gcaggtgctg gtcgttttaa
     3841 atatattcaa tttagtgatc atggaattgc accaagtaag gcagagcatt tccatatttt
     3901 ctttggtgga gaaagtcaag aaaaactcta taatgaaatg cataattggc ctactttcta
     3961 tccagcttca ttgtctaaac atgaaattgc tcaagaaatg atggctcatt aaaatccaat
     4021 ttttggagga aatacatggt aagaaaagta ttattgtcta tggattccaa gaatattgat
     4081 gcttatcggc gttatcgatt tgcaaagcaa atgagattaa atgggagtac attagctgat
     4141 attgctgcaa ctttacatgt tagtattgac acagttcata gagtattaaa acgggatcct
     4201 gattgttgtt ttatcaaggt caatactgga agaagtagac gtttagcaaa acggcataat
     4261 agcttggcca attaattgat aataccagag tagatcattt ttcccttatt tggatttgat
     4321 ctgcttttta ttatgtcttg aattgtcaaa tcaagcgcaa cactttatca aagaagactt
     4381 cataaggtgt tctccaatct aaacactttc taggtctgtt attcagtttt tcaatcatct
     4441 gatttatcgt tgagttatct accgtagcta tctctttcga ttttggcaag tattctcgaa
     4501 tgagtctatt cgtattttaa tttgttcatt gttgccaagg gcatgaggat ctggaaaata
     4561 aaagggcata ttattcaatg cttctgtaac tgcgaaatga ttggagaatt cttttcctct
     4621 atctggagtg atcgttttga ccgcctcatt tggaatactg cttaaaagtt caatcatttt
     4681 ctcgctcaca taagcggctt tctttctggg gaccttcttt cctgctaaaa ggaagcatga
     4741 ttttctgtct gtcaaagtca ctaaacaagt accaccagtt ttgccagcta caatatcggc
     4801 tttccaatga ccaaaatcac ttctatcatc tgcggatttt ggacggccat ggatcgaatg
     4861 agtaaggcaa atctttccac gagactcgac atgatttttt gtatgtcttg tttttcctcg
     4921 atggtgcaat gaacggatca ggcctttatt gccgtgtgag aggggttctg tatcgaaaag
     4981 atcattgcaa attgcacgtt agatcgtgat aaaactaatt gaaaagtcca tatgttcatg
     5041 cttcaaacga ttcgagattt cctctggcga ccactgaaaa tcgacaaata aatgacgaac
     5101 aattgaccaa actcacggat catttagaat gtgataacgt ccgcattttt ttcttcgata
     5161 agcataattt ttttccgctt tggaaggtga atagtttttt tcttgtttct tctcagttca
     5221 tgtaaaatag taaacgggct atgctgaatg tcgttgccaa ttatactaat agaaaatcct
     5281 tcttcgtgaa gcagaaagat tctttctcgt tcgagtatag taagatgacg atactggctc
     5341 ataattattt tccttctagg agtgttctcg acaaacttat actagttgga tatcgattat
     5401 gactcatttt tatgtgttgc acttaaagtg taaattcaag gtatagaaag aggttcccta
     5461 tgaaaaaaat acctattaca atcttaactg gctatcttgg ttcaggaaaa acgatacttc
     5521 taaatcatat tctgtacggt gatcacggaa aggaaattgc tgtcattgta aatgacatag
     5581 gggaagtaaa tgttgatggg gtattagtcg acaagaaagg ttttaaaaga actggagaaa
     5641 aacttgtttc gatgccgaat ggatgcattt gttgtacatt acgcgaagat ttgattgttg
     5701 aactagatca attagtgcaa ttttctgact tgaatcaaat tgttattgaa gcttcaggaa
     5761 tcagcaaacc aattccaatt attcaagcaa ttatattagc taaaaaccct ttagacattg
     5821 atttgaccca acgattagag attggtgcca ttattatagt agtggatgta aaacgttttt
     5881 gggataattt cgaaacgggt gaaaagattc aggaaagaaa agctgaaggt aatgtagttg
     5941 aagaagaaca ggatattcgt ggcttgttaa ttgatcaatt cgagtgttgt aacatattac
     6001 ttttaaataa tagtgactta gtgtcaacca agacgattta caaaattaac ggtctaattg
     6061 ctaagttaca gtccaatgcc aaaataatta ggacaattaa aggtgaagta gacttatcga
     6121 aaattctaaa tacaaatctt tttaatatag atgagacttc ctattcagtg ggctggttca
     6181 aagagttaga gcttggctat caaaatcata ttcctgaaac agaagaatat ggtatctcaa
     6241 gttttatcta tcgaaatcgg ttactccttg acgcacaaaa atttgcccat cttacggata
     6301 aaaattttcc tggcaatatt acaagagcaa aagggtttct ttggtttgcc caacatagtg
     6361 atttttcgac gatctttgaa acatcgggta gctataaaag tattgaatca ttaaattatt
     6421 gggtagctag tttacctaaa attgagtgtc aaatgattat acaaaaaaat cccgaattga
     6481 aggaagcctg gcatccgttg tttggtgaac gcattaataa actagttttt attggtatga
     6541 agatggatca acaatgtatt aaggaacaac ttgagggttg tttaactgat tctcttaatg
     6601 cagataattt ccgaaaaatt tcaccatttc catggaaaaa gtctaatatg tttagccaga
     6661 tatcgttaat gaaattttta agaaaagctg gtgtcaagat aggcgatgtc ataattattg
     6721 gcattttgat tattacctct tttattccct tatttgtatt ctctatagaa aaggagaatg
     6781 aaacaactga agatgctatc aaatatgcca tcgttcgaat tgatggcaag gaaatggatc
     6841 gcttcgattt ggataagatc aatcataaac tcgtgaatta tcatcctgcg aagggacaat
     6901 ataatattgt tgagattaaa gatggaagaa ttcgagttaa agaagataat agtcctgatc
     6961 aaatcgcggt tagaactgga tggatctcaa aacccggtca aacgagtatt tgtttacccc
     7021 ataagttagt tattagtatt gagaaaaaag aaagcacaga ttactacatt tactaatctg
     7081 gaaatagatg aggaggtttt taataagaaa aagatattat tattaataat agcaggggct
     7141 ttattaagtg tgttaagcgc ttgtggacaa gaaaaagaag cggtgacaac aggcacaagt
     7201 atctttaacg ggacctgcaa tggtttagtt aacagtcggt tagattactt attttggctc
     7261 ttcgtcaatg agtgttggtg aagaaattca atagaataat cgagatactc acacggctag
     7321 acagctatct tgtctagccg tgttgttgtt ctggctttag tcagttgggt agtattctta
     7381 gttttcttaa aatattttcc tcgatataaa aagattcgtt ctcggtagtt ttgaaagttt
     7441 ctaaagccat aggcaattcg ttttagtact ttgatatggt tattcaaaca ttctataggg
     7501 ccgttggaat agggaacgcg caacgctcgt ttgatttctg tttggtattt cttgaaggtc
     7561 gtgaacactg gttggtagtg ctctggcaac tccttgtagt cttcttttag gagcgcgacg
     7621 aattttggaa cagcttgtct tctaatagcg gaaagaaaat cctggtagac ttcgtagcct
     7681 cgctttaagg agtcatcata agataatagc cgatcgacta tctccgcttc tgtcagatga
     7741 tctcgaaatg acggacgcca gtagcgatgc tggcccttca attcccacgc attcttttga
     7801 agtagtctcc agtatttctt taagtgcttc gaccgacgat cccttttttt aaaggtcttc
     7861 attacttgaa ttcggtgatt ggtaaaggcc cgatcgatgt gttggctaat atgaaagcga
     7921 tcggcgacga ttcgggcatt cggaaaacgc tctttcacca atgtgcgata gggtgtatag
     7981 aaatctgaaa ccactagacg tacttgttca cggacttttc tagggtagcg caagaaatag
     8041 ccgcgtaaag gattgagttg ccgattttcc acaatatcaa tcagttgata ggtcttgccg
     8101 tccatcatga caaagctcat ggctcccgag acatttttca ctgatttgaa ttcatcgaaa
     8161 cacaccactt ctggtaacag ctggttcaaa gaaatggttt taggccgaag gctgcgaagt
     8221 attcgaatga cagtggtcgg agaaatgtgc ttcatacgtg cgatcaaaga catagaaaga
     8281 ggttcgctta atagctcaag aatggcttgt ttgactctgc gagcaatgga gcagcgacga
     8341 tcactaactg aatcttctgc taaaaaagtc tttccacagt gtttacattt gaagcgctgt
     8401 ttgttaatcc gcagaatggt cttgtagtta ctgacatcat tcaataagat ggatactttt
     8461 ttccagccct atttaatgat cgtttgttca ttttgatagt ggcgatgaaa gcattcctcc
     8521 ggttgatagg tcaatgtgcc atcaaaagca aaacatgttt cgtcattgat gcgctctttg
     8581 cgaaaggcat cttcatgaaa ggtaagattt aggtctagaa tatctagtaa ctctttggta
     8641 aactctgaat aggacatctt gaaacactac tttgaatggt ttttgtcgac tttattctaa
     8701 aggattttaa ggtgtctgtt tgcgtttatt agaaaaaaga aaaagtattg gcaacagaag
     8761 gcgtcaccaa cactagatat tatagatccc ttattttctt cgcttcaaat tgtcaaggag
     8821 tcatcataaa ttttgtatgg attcttttgt ttgggtagta gtcttctaaa taattttgga
     8881 ttaacacctt catctctatt ttacttttat atttgttgga gtcgattaat tctcatttga
     8941 ttgatcgatg aaacgcttca attactgcat tgtcaacagg agtcccagtt tggctcactg
     9001 aatgtgtgat gtggtggtcg ttcaacagct cttgataaat aaaagaccga tgctggctac
     9061 ctctatcgga atgaattacc gtaggcaatt ctccttaata aatttgtaat ggacggacga
     9121 caatctcttt tttcatgtgt gaatctacca tatagtaacg tagaatacga gttgctaagt
     9181 caatataggt ggacaaatag aggcgaccgt cattacatgg aatgtaagta atatccatca
     9241 cccaaacagc atcaatttgg ttctgttcaa attatcgatt caacattttt ttaccatttc
     9301 tttgattgtt ttttctctac catgagaaga tttgcgtcga tgaaatcctc ttgtgcataa
     9361 attcatttca cgcataagaa cagctacaac acgtttattg atttcgattc cttcatcgta
     9421 aagtttttga gtgatccctg gagatccgta tcgatctttg tgttcgtaga acactcgtct
     9481 tcctctttta gtcgtttatt ttcctgttca agaatgtaga aatctgcttt atcaggtaat
     9541 ctttttcctt gtccagcaaa agcatttttc ccgtatcgac gatattctga aacccatcgg
     9601 gaaattgcta gacgagagat attgtattct tcagcaattt tcttggtagt tacttttttc
     9661 tcaaggatat cctgtgaaat ctttagttta aatttacgat catatgtttt tctcaataga
     9721 gttcattcct tccggtaacg taactgatag tcaagaaaag tgtatcatag cccaacttag
     9781 tatcagggtt tgtcaactaa actgtggaag ttgatagata agagttttta acaaccaaaa
     9841 ttctcttgac tatttttgaa atcagacaaa ttttgattgg acacatagtt gaataaatct
     9901 accgtcgtta cggaaggtaa atcgcatgct tttcaattct agaggagaag tcctcgttga
     9961 agtaccatag cccagttctg gattcgacct cctgcccact tcatacgtaa ataaagtaat
    10021 tttaggagtg agactgtgac aaaagttatt tttaagctaa aaacgaatta aaaaacgttg
    10081 ataattaaaa tcattcgttt tagattctat gaatcattat agaacgctgt aaaatcgata
    10141 ctttataatt ataaagaaga tagtttcaaa tttattgttc gaaatttgaa actatctttt
    10201 tacttatgtc acagactccc ttagttgagt tattctttaa tttcgaattt cgagatagct
    10261 agatatattg caagcataca ttcttgataa caatcttgat catattttcc agttctccag
    10321 gattgcttat gaatcaaaga gctaaatctt ttgagaattg cctcaacagc ttcttcattt
    10381 ccagcctttg ctaaaatgaa atcttctttt aaagaattca taaatctacc ttcttcccat
    10441 ggacttataa tctatttctt tgggaaggag gagaacgagc aaagaagcat acaaaattag
    10501 ttattatgca gatattaaac cagcattttt tgaatttttt tgtaaagtcg atgttttaaa
    10561 tttgtcgcac cctgtcttgt aatccccaga acctttccaa tttctttatc agttttatca
    10621 aagataaatt tttcgataag aaaaatttgt tcaggttctt tcaacaaagg aaggattttt
    10681 gctaatttta tatcttcaac aaggagagtc acatttaaaa cattaatcgg ttgtttaaat
    10741 tttatagtat ctttagtaaa caaatatggt gggagttgat caagttgttc atgtttttga
    10801 atttcttctt gttttttata ataagtatta gcggtgttca aaatgacctt ttcaaagaat
    10861 cgaatcaact gggcatttac gcgttcgtcg ttatctgaca tattgcacac ctcctccatt
    10921 aagatttaaa gggaaaagag gcaaaaaaca cgaaaagaag ctaatgcaat tatgctgcgc
    10981 tgcgaataac ttctataagc tcacatgcat tgataggact gctgatgttt attttcaaaa
    11041 atgttttttt agttgataat ggatagttat ctttatactt agaaaagaaa attcatatat
    11101 cttcttaaat atcaaacatg tccttatggc taagaaaatg tcttgagctt tttacgtata
    11161 ataaatcttt tctaaaacct ccttttggat aatattctta ttcgtgtata gattgtattt
    11221 tttatttctt cccccttcat aattaacaac tagaaaagag ttcgaataga cacgtaattg
    11281 aacgaaaatt tttattggat tcccaaattg gaatatttag aaacgaaaaa ttcctattat
    11341 ctgtatagtg cttagataat aacggatcat aataattatt gtctttgaac tagatatatg
    11401 taaatagtat tcatcatgat gaaaaatgat gagttctcgg tgataaaatg tactttttat
    11461 ggtggaatat acatgaaagc gataagtgga tattttataa tgaagtaagt tagcttattt
    11521 tgacagagga atagtatttt agataacgta taaaatacta tttaatgatg tagaaaggaa
    11581 agagagaaac aaaagtgttt tcagataaag aagtcttatt aaagtctctt catgtttgtt
    11641 taaagttacc tatcgtggtt tttaattccg aattcaatat gataaaagag tatcgctcag
    11701 atagaactac ttattttttt tatgattata aaaagttact aactgataat attaaaaaaa
    11761 ctaaagattt ccatttcttt actggtgatt ttaatgagat gtttcttcta tacatgttta
    11821 aaaccagata ttacttattt ggtccattta gagcaaataa tattgataaa gattttttta
    11881 aactaaaaat gaacaatttg aatgttgcaa tggctgatag agaacgactc tataattcat
    11941 tgcaaaattt gactttgtat tctttaggag acattcgaga tattctgatt ttagttcatt
    12001 atttttttac tggaaaaata gaagatctat tccataaacc gttaattgaa tatacagaaa
    12061 atctaagtaa aattatcgag caaatcaaaa tagataatct gttatcacaa aattacgatc
    12121 cagaaatata tctgtttctt tatgaaaata aaatactgga atatgttaaa aatggagata
    12181 ttcgaaattt agaaaacatg gtttttaatc tgagtaatgg aataattcca agtgttagtg
    12241 gagatacgat tcggtctgaa aaaaattatt ctatcattgt ttttgaaaag ttagcacaaa
    12301 cgtctataac attaggaatg gatataatag aagcgtatca aagtagagat gctttgatac
    12361 aagaaaacga attagctgta tcgttacctg aggtcttaaa agtgagggat tctgggattg
    12421 tttattatac taaggaaatc ggaaaaacta agatagagca tctttctccc ttaatttctt
    12481 ctgtcgttca attcatcggc ttaaatatct ataaaagaat tactgtaaag gaaatagcta
    12541 attatttttc tgtaagtgaa actaaattaa gagaaagctt taagaatgaa atgcatatta
    12601 cgatttataa ttattgtcaa tggcggaata aaaatgctgt tttatggcgg tttaaaaatg
//
LOCUS       DAFEKH010000074        12246 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.077, whole genome shotgun sequence.
ACCESSION   DAFEKH010000074
VERSION     DAFEKH010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.077"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(17..1246)
                     /gene="hflX"
                     /locus_tag="LP386_002504"
     CDS             complement(17..1246)
                     /gene="hflX"
                     /locus_tag="LP386_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBL1919705.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
     gene            complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="LP386_002505"
     CDS             complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="LP386_002505"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HBL1919706.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            complement(2169..2906)
                     /locus_tag="LP386_002506"
     CDS             complement(2169..2906)
                     /locus_tag="LP386_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBL1919707.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            complement(2997..3524)
                     /locus_tag="LP386_002507"
     CDS             complement(2997..3524)
                     /locus_tag="LP386_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919708.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            3704..4297
                     /gene="clpP"
                     /locus_tag="LP386_002508"
     CDS             3704..4297
                     /gene="clpP"
                     /locus_tag="LP386_002508"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBL1919709.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            complement(4401..4886)
                     /locus_tag="LP386_002509"
     CDS             complement(4401..4886)
                     /locus_tag="LP386_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HBL1919710.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(5039..5236)
                     /locus_tag="LP386_002510"
     CDS             complement(5039..5236)
                     /locus_tag="LP386_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919711.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="LP386_002511"
     CDS             complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="LP386_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HBL1919712.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="LP386_002512"
     CDS             complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="LP386_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HBL1919713.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            9211..9423
                     /locus_tag="LP386_002513"
     CDS             9211..9423
                     /locus_tag="LP386_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HBL1919714.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9425..11104
                     /locus_tag="LP386_002514"
     CDS             9425..11104
                     /locus_tag="LP386_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBL1919715.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(11358..11558)
                     /locus_tag="LP386_002515"
     CDS             complement(11358..11558)
                     /locus_tag="LP386_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL1919716.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(11708..11869)
                     /locus_tag="LP386_002516"
                     /pseudo
     CDS             complement(11708..11869)
                     /locus_tag="LP386_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein"
BASE COUNT         3575 a         2636 c         2117 g         3918 t
ORIGIN      
        1 ttaaaaaaat aaaattttat tggttttttc ttaaccattt tgaattggtt tttgcaaacc
       61 ctttaacttc atattcgttt gtttcttcca tgtacgcttc gtccaaaacc attgtttgtc
      121 ttctcaactc gcttaatttc tgtccttcgt tgcttggcac agaaagtgta taaggggtca
      181 ttagttccat cagctgacgt ttgattgctt cgatcaacgc catcttacct tctttcgtct
      241 gagtagaaat caatacattt gggaatagcg taggcgtgaa catcgctggg tcgatctggt
      301 ctgccttatt gtaaacagtc agtatcggca tttctttcat attcagttca tccatcaatt
      361 ttaagacagt ctgctcctgt aaaatacgat ctggagaact agcatcgact acatgtagca
      421 aaagatccat attttgactt tcttctaatg tagaatggaa agcatcgatc agttgcgtag
      481 gcaggtcttg gatgaacccg acggtatccg ttacagtaat ctcaaatcct tcagcaaaac
      541 gccatctctt agtcaatgga tctaacgttg caaacaattg atctttcgaa taagtatccg
      601 cttgtgtcaa tagattcaag atagttgact tcccggcatt cgtgtagcca ataagtccaa
      661 tctgaaaaat ctcgctattt tttctttttt ggcgattgcg ctctcgatga gcttctactt
      721 ctttcaattc tttcttaaca gcaaaaattt tattccgtat atgtcggcgg tctgtttcta
      781 actttgtttc acctggccct cttgttccga tcccaccgcc aagacgagat aatgttttcc
      841 cttgccctac taaacgaggc agcaggtatt ctaactgagc aagttcaacc tgcagcttcc
      901 cttctttcga acgagcacgc atcgcaaaaa tatctaagat aagctgcacg cgatcaatta
      961 ccggaagacc aacagcatcg gtaatcagtt ggctctgtct cggagttagc tcatgattaa
     1021 agatgatcaa atccgcttca tgcgcatccg cttgttgaac taattcttgt aatttccctt
     1081 taccgataat cgtttgccga tccacttgtg gtctcttttg tgtaattgtg aatacgactt
     1141 ctcctgatgc ggtattcgtc agctgaacta gctcttccat tgactctgaa aagtaacgct
     1201 ggtttgcttc ggtttctacc cctacgatga tcactttttc ttccatttta ttccgcctcc
     1261 agccattttt tgattgtttg ctcaatctga cttttttgat ttggctcact tataagatca
     1321 aaccactgtg catccaaacg gttacgaaac cacgtcaact gacgtttcgc gtatcttctc
     1381 gaatgtagtt tgacttgttc tgttgcttct tccaatgttt ctttcccttc aaaataaggg
     1441 aaaaattctt tatatccaat accttgactg gcctggactt ctccaagctc atacacctta
     1501 cgcgcttctg ctactaaacc ttctgctagc atcaaatcga ctctttgatt gattcgttca
     1561 taaagaatac tacgcttcgt atctaatcca atcatgaggt aatcatacaa ttgctttggc
     1621 tcttctttag gtgccgtgat actatgtcct gtcgtctcta aaacttccag agctcttatc
     1681 actttgcgtt gattgttcca gtggattttc tcagcagctg ccgggtcttt ttctttcaac
     1741 tgattccata atgcttggga accaattgtt tcagctaacg tttcatactt ttttctaatc
     1801 tcaggattcg cttcttctgt cgctcctaac tgataatcat atagaaggga ttggatatag
     1861 agacccgtac caccagctat gataggtagg tgccctcggt tcgcaatctc ggtaatcaat
     1921 tgtcgacctg aatgctgaaa atcagcggct gagtaacgtt gagtaggttc gatcacatca
     1981 atcaaatgat gcggaacatt attcatctct tcttctttga tttttgctgt accgatatcc
     2041 agatttttat agatttgcaa tgaatcacca ctgatgatct ctcctccaaa tagttgtgcg
     2101 agttccacac ttagcgctgt tttaccgact gctgtcggac cgacgatcac taatactttt
     2161 tccatatttt acctactttt cgttgattgt ttccaccgaa gagctttctc cggaaaatca
     2221 gttattattc catctatttt gagttcttga catttggcca tttcttcttc atcgttaatc
     2281 gtccatgcac gaattgcttt tggaaaatca gctgcctgga ctggatgttc gaacaaccaa
     2341 gtattttttg gatgtactcc ttctatataa ggggtttctg ctgctagttg gatcttttta
     2401 tcagaagtac tcatcaataa gtccagctgt atctccggtt ccagtaatgc gattttttcc
     2461 aaagaatcca aatgaaagct gcaatatgca tgttgaaaag gccaatctct actttttaat
     2521 gtttcggcta atttttcttc gataccggga tattcatact gatcagtttt aatttcaatc
     2581 attagcatcc ctcggtaatt tttttggagg agcagtccta acacttctct caattcagga
     2641 actttagctg ctggaaattc tttgctgaat ttgccccctg cattcaattt tttgagttct
     2701 tccaatgttt tttctcgaat cagcccttta ccgttagtcg tccggtccac ttcttcgtcg
     2761 tgcataacga tcaaataacc atctttgctt agatggacat ctagttcgat accatctgca
     2821 cctactcgta cagcttctgc aaatgcagga agcgtatttt ctgggtgggt gccgctgctt
     2881 ccgcgatggg catagatttg taacatcttt cttcactccg ttcagttcta ttgtatcatt
     2941 aagaaaaaaa gaaagcatta ccacgctctc atgtgcaacg gcaatgcttc aaaatatcag
     3001 ctccaaacat catctttcga gaagaaacca atcggctggc gcgtcatagt cttcaactga
     3061 gctttttttt cattgatcat ttcagtcaga ctatccgtaa aattctctaa aatcacgcgt
     3121 ccgcctttat aagcatatcc accaatcttc attgtttcat ctggagataa aatcactttt
     3181 cgatgggaga tattcttaaa tagctcgtct aaaatataat ttggcagata aaaactattt
     3241 tgcgctgaaa atgattggag atacgcaaaa tcgtcaatcg tgatataaca atcatcaaat
     3301 gcatcaaagc tgacatattc ttccatcagc gttgtccgtt tttgcaagat ctcgttgatc
     3361 tttttattta attgattcag cgtctcgatt tctttgactt tcaattccaa ttcacgtcta
     3421 cgctgttctt tattttccaa gtgacgcatt tgcagtatca tgccgatata gacaactaca
     3481 gcacctgtca gcactccgat aaggccagta ataccaacta tcaatctgtt gttcctcctt
     3541 gttttgtttc tctgcttatc ataccataaa gcgggtttat gcgactaatt tgcctaagtt
     3601 ttttatttga ccttttttga ccaaaaatgt atactacatt ttaggtatta gaaactaaat
     3661 tatggtacac tatttctaaa cgaaatcaag gaggaactct attatgaatt taattcctac
     3721 agtcattgaa caatcttcac gaggtgaaag agcttacgat atctactcac gtttattgaa
     3781 agaccgtatc atcatgttaa gcggccaagt aacagatgat cttgctaatt cgatcatcgc
     3841 ccaattgctt ttcttagacg ctcaagattc tgaaaaagat atctatcttt atatcaattc
     3901 tcctggtggt tcagttacag caggtatggc tatttacgac acaatgaact ttgtcaaagc
     3961 agatgtccaa acaattgtta tgggtatggc tgcttcaatg ggaagcttct tgctgacagc
     4021 tggtacaaaa ggtaaacgat ttgctttacc aaatgctgag atcatgatcc atcaacctct
     4081 tggcggcgct caagggcaag caactgaaat cgaaattgcg gcacgccata ttttgcaaac
     4141 acgcgaacgc ttaaacaaaa ttttagctga acgcactgga caaccgcttg aagtgattga
     4201 aaaagataca gatcgtgaca actatatgac agctgaacaa gcaaaagcat atggattgat
     4261 cgatgaagtc atggaaaaca gttcttcatt aaattaatct gtttcaaagg aagctttttt
     4321 aagctctctt atctaaacca aataaaaaag gatggtcaac tcaaactgac catccttttt
     4381 tattttatgg atgctactgc ctatctttgc tccttgaatt ttccttgcgc atgcatccga
     4441 cctatctcga cataatgctg gatgttttct ttgttttttt gtatttcttc ttttgtcaaa
     4501 ggacggatca ctttagctgg gcgaccaaaa gccaagacat taggaggaat aacttttcct
     4561 tctgttacta atgatccagc accaatcaaa ctattctcac caataaccgc atgattcaat
     4621 atcgtggtcc ccatcccgat cagcgcccct ttttcgattg tacagccatg tagcatgcac
     4681 tgatgtccta ccgtcacatt ctccgcaata tctacaggtg catcatgatc gacatggatg
     4741 attgtaccat cttggatatt cgttctttgt cctattttta tccaattact gtccccgcgt
     4801 aaaacagctt gataccagat cgtcacatct tctgacaatg tcacatcacc aatcactgtg
     4861 gcatttgatg ctataaaccg ttccatattt atttttctcc tttcattttt tgtagaaact
     4921 aatcctattg aataaaggta tcatagcata tatttatttc ataagaaaaa aaacaggtaa
     4981 aacctgctca ggccagatgt ctatttacag tatctggtaa ctgacgtttt acctgttttt
     5041 attgtacatc tatattttct tctattactt tttttaaaat taattcgtac acttctattt
     5101 gtgctgccaa gcgttcgatt tgaaactcat tttcaaaaaa atcagctgaa tcaaaaggct
     5161 tcgtctgaca gacgtgcgtt aaacgatcaa cttctctttt ggcttcagta attttttcat
     5221 ttaaaaactg ttccatctcc gtgtcctcac ttttcttgat aactttactt taccattatc
     5281 aagaatagag aacaaaaaat aagttttaaa ctgttttatt cttatatgac ttattctgct
     5341 tcctcagcaa attggctgtt atacagtttt tcataaaatc caccttgtgc caataaactc
     5401 tcatgcgttc ctttttcaat gatctgacct tgatccatca ctagaatcag atctgcatca
     5461 cggattgtcg ataaacggtg agcgatgacg aaacttgtcc gtccctccat cacgcgatcc
     5521 attgcttttt gaatcaacgc ttctaaacgg gtgtctactg aacttgttgc ttcatctaaa
     5581 atcaagattt taggatcgga gaccactgct cgggcaatcg tcagcaactg tttttgtcct
     5641 aaagacacat tgtctccctc agaattgatg gccatatcat atccatctgg catcgttcgg
     5701 ataaaatgat ctacgtttgc tgttttcgca gcatcaacta cttcataatc tgtcgcatca
     5761 agctttccga agcggatatt atctgcaatc gttccttgat aaagccatgc atcttgcaag
     5821 accataccaa atagcgaacg cacatcactg cgactcattg atttggtgtc gattccatca
     5881 atccttattg ctcctttgtc tacgtcataa aaacgcatca atagattgat caatgtcgtc
     5941 ttgccggcac cggtcggacc gaccacagct acggtttgac cagctttcac ttcaaaattc
     6001 aaatcttgga ttaatggttt cttcggatca tatgcaaaat cgacatgatc gaatgtcaca
     6061 tctcctaaaa tcgtttctgg cagtgaagca tctactttgt tttctttttc ttctggctca
     6121 tctaaaatct cgaatacacg tttcgttgcc gctgatgcac tttgcaaaac tgaagacaat
     6181 tgtgtcacgt tccccattgg ctgactgatt tgccaaatat attggatgaa tgcttgtagt
     6241 tgaccgacaa cgatcgcccc agtaataaca taaaagcttc ctagaacagc cataccaata
     6301 taagtagcat aggcagttaa ttgaactaga ggcatcatca agccagaaat gaatgctgca
     6361 cgaaacccaa agtatttcaa gctgtgatta acttttttga atccttccaa tgtttctttt
     6421 tcgcgtccat atactttcaa tacactaaaa cctgtcatat tttcttggac gtagccgttt
     6481 agctcaccaa gagaattctg catgctttga aaatatttct gcgaagcatt gatcactcgt
     6541 tttgagatcc agatcgatgt tggaatcatg atcatagaga tcagcgccat catcggctgg
     6601 atataaaaca tcattgctgc agccaacgta attcccaata tcgcatttac gataccaata
     6661 aaagcttgtt gtaaagcacc gctgactgca tctacatcat tcgtcacacg agacaaaata
     6721 tttccttgct ggtttttatc gaaatatgaa accggaagac gattgatttt ttcttctatg
     6781 tctcttctca aatcatgcat ggcactttga acgacatttg tcatcaaaac accagaaagt
     6841 aattgcgaaa tacaataccc tattccaaca actgtgatcc aaatgagaca tttgaatata
     6901 taagaaaaat tgattgattc gccattggca atattacggc tgatttctgt agtaggaagt
     6961 cctgtaacat atggcaaagc cacgttgaaa gccactgtca gaactgtaaa taggatcact
     7021 aaaagaaaag tctcacgata cggtctgata tatcgagcta aacgttttaa ggaagaaaag
     7081 gtttttttca tgctaattcc tcctttgata attgagaagc ggcaatatca taataaatcg
     7141 ggcatttttc caacaactcc cgatgcgtcc ccataccgac gacttctcct tcatttaata
     7201 cgatgatctt atctgcatgc atgatcgttc ccacacgttg tgctacgatc aatacagtag
     7261 attctgtcgt ttcttttttc agacgagcac gtaacttcgc atccgtttga taatctaatg
     7321 cagaaaagct gtcatcaaaa atatagattt ccggacggcg tatgatggct ctggctattg
     7381 ccaatcgttg tttttgtcca cctgaaaaat tggaaccacc ttctgataaa tgttcattaa
     7441 atccatctgg ttttcgagaa atgaattctg aagcttgagc aatctcagct gcacgttcca
     7501 tttcttcttg cgtagcatct tctttcccgt atcgcaaatt atctgcaatc gttccagtaa
     7561 atagcagcgc tttttgcgga ataaacccaa tcttatctcg caacttgctt agccgataat
     7621 ctctcacgtc tactccatcg atcaagatct ttccttcact cacatcataa aagcgaggga
     7681 tcaattggat caacgtagat tttccgctac cggtacttcc aataaaagca acggtctctc
     7741 ctggagaggc tgtaaaactg acatttcgta tcactggctc ttgcgaatgg cctggataag
     7801 caaatgttac attttgaaat tcgatatacc ctttagtttt tgtatcagat ataccatttg
     7861 gatcttctac aatcgaaggt ttggcatcta gggcttcttg gatacgtcca gctgaaacag
     7921 ctgctcttgg atacatcatg aacacactag caaataacat gaatgagaac aaggcatgga
     7981 atatatactc gataaacgca atcaaatctc ctacacgaag ctcgcctgca tcgatttgca
     8041 ctgccccgct ccagatgatc aataccatta cgatattaaa taagaaataa aaacccggtt
     8101 gtgcaacagc catcaaacgg aataagcttt ttgaactaga agcataattc tcattgacta
     8161 cagcaaaacg tttttcttca aacttttcat tgacgaatgc acgaatcaca cgcaatcctg
     8221 aaagattttc ccgcaagata ctgttgattt tatctaagtt tttttgttgc tttttagata
     8281 acggttcaga caccttagca atcgctacga ctgccaataa tagtaaaggt aatgcaccta
     8341 ctacatacaa actgagtgtc acacttgtac gcatgaccat gtacaaactg acaatgaaca
     8401 tcattggtgc cataaaaccg atacgtaaaa tattttgcag gaacaacatg atctgataag
     8461 catcgtttgt tgtacgagtg atcaatgaag atacgcctag attttcgtat tcctgatgcg
     8521 aataactttg gatcttttcg aacaaatcat ctcgaatatc tgctacgata ttagtcgtaa
     8581 tcctcgaacc aaaataacct aacaagatat tcaaaataat accgattaca gtaataacga
     8641 tcataaatat cccttgttgc ttcacataat caaaatcatc attgcggatt cctacatcga
     8701 tcatacgtgc taaaatcgta ggaagtccta attcaatcaa aataaaacca aatacgcata
     8761 tgaaattgaa aaacaagaat ttcttataac gcatggtata atgccacatt agtttcactt
     8821 tctcatctcc ttttaatctt ttgttacatt ttcattacta aaaatgatag cacaacgagc
     8881 ctattaatag aacacttctc tcataaaaaa gtcattatga ttatagcggg atgataaaca
     8941 ttgatttttt ctttcaatct agttgatttc tatacttatt tgctgtttta tgctagaata
     9001 acaattaatt gttgtatatt ttttatacag aaggtacggt tgaaaaaata tccgaacaga
     9061 taagcaaaaa cgaggcttgt ctctttgact cgaatccagt attctagtca aagcatatga
     9121 aaaaccaggt ggcttgtccc ctcgttttgt gttgtctaaa aaaatcaact agctaaatca
     9181 ctgctttacg cagataaagg agacaaaaca atgatctata aagtttatta tcaagaaaca
     9241 aaagtacgca accctaaacg ggaagaaaca aaatctcttt acattgaggc aaaaagcgat
     9301 gtagacgctc gccaacgtgt ggaagaaaat accccataca atattgaatt cgttcaactt
     9361 ctagaaggaa gtcatctaga gtacgaaaaa gaaaatgctg atttctcatt agtggagttt
     9421 taatatgaaa ctttccatca aaaataacga gacaggcgtc tttgctattg gtggattagg
     9481 tgaaatcggg aaaaatacgt atggggtaca attccaagat gaaatcattt tgattgatgc
     9541 cgggatcaaa ttcccggaag acgatttact tggaattgac tatgtcattc ccgactacag
     9601 ctacatcata caaaacttac acaaagtaaa agccttggtg attactcacg ggcacgaaga
     9661 ccacatcggc ggaataccct acttgctgaa acaagcaaat attcctatct atgctggtcc
     9721 tctcgcatta gcgttgatca caaacaaatt agatgagcat ggcttgcttc gagatgcaga
     9781 gctccatgag atcaatgaag atacgatcat ccgttttaga aagacttctg tcagcttttt
     9841 cagaacgacc catagtatcc cagatgcatt agggatcgtg gtgaaaacac cttctggaaa
     9901 tatcgtagcg actggagact tcaaattcga tttcactcct gttggcgaac cagcaaactt
     9961 gcataaaatg gctcgtatcg gggaagaagg agtcttgtgc cttttatctg atagtacaaa
    10021 tgctgagatt ccaacattta ctaaatcaga aaaaacgatt gggcattcta ttttgaagat
    10081 cttttcaaaa atcgaaggac gtatcatttt tgccagcttt gcttctaaca tcttccgttt
    10141 gcagcaagca gcagatgccg ctgtggcaac tggtcgtaaa atcgctgttt tcggacgaag
    10201 catggaaaat gccatcgtca acggtcaacg tttaggatat atcaaagttc cagacggcac
    10261 atttgtagat gcacacgaaa tcaatcgctt gcctgccaat gaaacgatga tcctatgtac
    10321 aggttctcaa ggagaagcga tggccgcgtt gagccgcatc gcgaatggta ctcaccgtca
    10381 aatccaaatc cagccagacg atacagtgat cttttcaagt tcacctattc ctggtaatac
    10441 aacaagtgtc aatcatttga tcaatttgct gtctgaagct ggtgcagaag tgattcacgg
    10501 aaaaatcaat aacatccata cttccggtca cggtggacaa gaagaacaaa aattaatgct
    10561 tcgtttgatg aagccaaaat attttattcc tgtccacgga gaattccgca tgttgaaagt
    10621 acatgcttct ctagcacaag atgtaggtgt tcctgcagaa aactgcttca tcatggaaaa
    10681 tggcgatgtt ttagcgttaa ctagcgattc tgcgcgtcct gctgggcatt ttgtggctgg
    10741 agatgtgtat atcgatggta gcgggatcgg tgatattggt aatgtcgttt tacgtgaccg
    10801 tcacctgctt tcagaagaag gtcttgtatt agctgtcgcg acagtggata tcaagaaaaa
    10861 agaaatcttg gctggtccag atattctctc tcgtggattt gtctacatgc gagaatcagg
    10921 agaaatgatc aatgaagctc agcgaatctt attccacgct ttaagagaat gtttgaatgg
    10981 acctgactgt tcagaatata aattgaaaga agcgatgact ggcgcgcttc agcctttctt
    11041 attcgaacgt acagaaagac atccaatgat tttgccaatg gtaatgacac cagatgaaga
    11101 ataaataaga ggttatgaaa tcagcacctt gtcctgaata taagagaaaa caaatgaaaa
    11161 acatgagaag ccatttttgt ttgttcttat tccttgatac aaggtggctc tttcatagcc
    11221 tcttaaattt atttactttt tcatacaaaa aaatacctgc cacaagagaa attgtctctt
    11281 gtggcaggta tttttgttac tcgctttgtt ctctcgtaaa aattgatgtc taccatcaat
    11341 ttgatttaca gataaaatta agcttttaca acgtttgcag cttgtgggcc gcggtctgat
    11401 tcttcaacgt cgaaagtcac tgcttgacct tcttctaatg ttttgaatcc gtcaccttgg
    11461 atagctgaga agtgaacgaa tacgtcgctt ccatcttcac gtgagataaa tccaaatcct
    11521 ttttcagcgt tgaaccattt tactgttccg ttttccataa taatatcctc ctcgtgccaa
    11581 aagcactaat ttaaattgta acattgctcg tgtacgatag aggtgcaaca gatgtttcaa
    11641 cttctattcc caaacaaaat tacaatataa ttgtacactt gcttcatttt ttttgcaaga
    11701 aagcaactta cttctcttcc atcattcctt cttctctcaa actaaaatat cgtttgcgtc
    11761 cgatgatcaa gtggtccagt acagtgatcc ccatcatttc tccacacttt tgtatccttt
    11821 tggtaaaatt catatcctgc tgcgatggaa taacattacc agaaggataa tataggttag
    11881 tacacgtata aaaatatctt ttatattgac acaatttatt taacaagtat aataataatt
    11941 gaaagtgaat ttaaacaaat atacaccata aacacaacgt acctgcgaat acgttgtgtt
    12001 tttttctttt tcaaaaaaag acgcttaccg ctgcgaaaca gtaagcgcca ttgtcggctc
    12061 taatgtttat ctagccaatg actaaataat gccaaagtta aaccaattaa caatggcaag
    12121 agcacgtgct ccaaagtgaa ttcaaacaaa tcatacacct cctcccacga aaatctctgt
    12181 ggaagcgacg agccgacatt ttattatacc attattgaat tttatttttt atcaaataga
    12241 ttaaat
//
LOCUS       DAFEKH010000075        11743 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.078, whole genome shotgun sequence.
ACCESSION   DAFEKH010000075
VERSION     DAFEKH010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11743
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.078"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            469..1032
                     /locus_tag="LP386_002517"
     CDS             469..1032
                     /locus_tag="LP386_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919717.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(1093..1437)
                     /locus_tag="LP386_002518"
     CDS             complement(1093..1437)
                     /locus_tag="LP386_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919718.1"
                     /translation="MISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFHYSPYRLF
                     QYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHDEVYLAEC
                     LANLEQKGIYLT"
     gene            complement(1534..1779)
                     /locus_tag="LP386_002519"
     CDS             complement(1534..1779)
                     /locus_tag="LP386_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1919719.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(1849..2103)
                     /locus_tag="LP386_002520"
     CDS             complement(1849..2103)
                     /locus_tag="LP386_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919720.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(2267..2590)
                     /locus_tag="LP386_002521"
     CDS             complement(2267..2590)
                     /locus_tag="LP386_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919721.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            2777..2850
                     /locus_tag="LP386_002522"
     tRNA            2777..2850
                     /locus_tag="LP386_002522"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2811..2813,aa:Ile,seq:cat)
     gene            complement(3235..3732)
                     /locus_tag="LP386_002523"
     CDS             complement(3235..3732)
                     /locus_tag="LP386_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBL1919722.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(3772..4581)
                     /locus_tag="LP386_002524"
     CDS             complement(3772..4581)
                     /locus_tag="LP386_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL1919723.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIDMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            4915..5772
                     /locus_tag="LP386_002525"
     CDS             4915..5772
                     /locus_tag="LP386_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBL1919724.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            5765..6667
                     /locus_tag="LP386_002526"
     CDS             5765..6667
                     /locus_tag="LP386_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBL1919725.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            6700..7050
                     /locus_tag="LP386_002527"
     CDS             6700..7050
                     /locus_tag="LP386_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBL1919726.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            7099..8022
                     /locus_tag="LP386_002528"
     CDS             7099..8022
                     /locus_tag="LP386_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBL1919727.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            8100..8993
                     /locus_tag="LP386_002529"
     CDS             8100..8993
                     /locus_tag="LP386_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL1919728.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKVAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            9031..9594
                     /gene="amaP"
                     /locus_tag="LP386_002530"
     CDS             9031..9594
                     /gene="amaP"
                     /locus_tag="LP386_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBL1919729.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            9608..9796
                     /locus_tag="LP386_002531"
     CDS             9608..9796
                     /locus_tag="LP386_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBL1919730.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            9809..10711
                     /locus_tag="LP386_002532"
     CDS             9809..10711
                     /locus_tag="LP386_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBL1919731.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            10743..10985
                     /locus_tag="LP386_002533"
     CDS             10743..10985
                     /locus_tag="LP386_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBL1919732.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(11241..11612)
                     /locus_tag="LP386_002534"
     CDS             complement(11241..11612)
                     /locus_tag="LP386_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919733.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         4164 a         1982 c         2220 g         3377 t
ORIGIN      
        1 caattttgtg gagcgtgaag cttttatggt agaggaaaat acgaataaag tgatgttgat
       61 aaaaagattc ctatcttgaa tatgaatcga gatgtcttga aaatgaatga gtttgaccaa
      121 tcattatcct atcgaaattt acagtttcgt tcgattggtc tgtcaattaa tgaaaaagta
      181 aaaaagaata tgttctagga agagggcggc acatctaaat ttttaagtaa cggacagttc
      241 aaatatcaag cattgaaaga ggctatccta ctgtttgaag gaatacgaat atataaaaac
      301 gacaaagagg aaaaagtagt tcattaaatc ccttcaagtg atgaaagaat gagatctaat
      361 aaaacctgat ctttcatctg tttttttaat aacgtaataa tttttttatt ttttgtgctt
      421 tcgccgttat tgtagagtga tttagcattc ttatttttaa aaataactgt gttatatatt
      481 aaaaaaggca taatagttat aagctttttt aaagaatatt tagaaattat taattttcgt
      541 ctgaaaacaa aaaaagaaag cgttattatt ttagtctatt ttcagggggg gaaccttatg
      601 ataaaaaaac tatttttact atcaatatta acgctagcaa tggcaggttg ttctgactct
      661 ggcttagcaa ctgaactgat cacaaaatca actgaagcca cgacagagga gttaaaatgt
      721 ggaaacgatc acagtgacta cagaggctta aatcgacgat gcatgggaat attaggcaga
      781 agcaattgta agcatcgatg tagtaatcga agaaggtgta gaagaagcaa cagaaaaatc
      841 aaaagaaaga tcaaaagaag caatctgtgc tgtgcatcgt atacagacgt cgaagatgcg
      901 gtacttttaa accacgtcag gagatgttca tttatgtcta gggaagttgg cgatgaacca
      961 aaactagagt acgcttttag ttttgcacgt gaggatgaag ataaccctaa aacttacgac
     1021 attttagctt gatctaagat ggttaaagct ttttaatgaa gtaagaggag atagaaggct
     1081 tttctagtta tattaggtaa gataaattcc tttttgctcc aaatttgcta aacattctgc
     1141 tagataaact tcatcgtgtt ccggataaat cggcacgttg cgctctacag taggtaaatc
     1201 aaaaaatgct tcgcatgatt tgccacgata cataggattt ttccactctg gtgctgggct
     1261 gtaaccacgt ttttccattt catccatgac aagctgatga tattggaata atctataagg
     1321 agaatagtga aaaacataat ccacagtagc atgtttcttt ccccagccat ttcctcttaa
     1381 tgcacagcat tcccgatgtt gtcctaaaag ctgttgacga ggaagctttg aaatcaattt
     1441 ttcatgccat aatcacatag aaatgtctcc tttatatata gattgttaac cttagacgtt
     1501 aaatgaaaaa accagcacca aggctggaaa aaatcacttc agtttgcttg ctgtttctga
     1561 gcgaccaatt aggtaatcaa cggaaatatc gtaaaagtca gcgatataga ttaattcaat
     1621 gatgcttgga atttcttctc cttcttcgta cttacgatat ttgaataaag gaatacttaa
     1681 cgcgctagaa acagctactt gagataaaga tcggccagtt cttaagaaat tcagacgaca
     1741 acgtaaagta tccagtaaaa tagcttcttc gatactcatt taatcacctt tcattatagt
     1801 agaatagtta taatgactat agaaagctac acatgcaatc aatagtactc aatgtttttt
     1861 atttaaacgt atcaaataaa gaatgacgat caataaagac aaaaccagtc ctgataattc
     1921 ttctataaaa acactatcgg gttcaaagta gttgtaatta aaaactttcc acataaagta
     1981 gatagccgga agagtcaaaa tagctaaata aaaccgttct ttgttccaat tcataagata
     2041 aacaatactt gcgaccagtg cgaccgcagg cacccaaaac aaaactctca ccaacgtaat
     2101 catgtaacgg actcctcaac gattcatata ataaaagata acatgttatt gcatacatca
     2161 caaatgaaat gctaggaaaa taaaagaaga atagatcaat gaaaaatgaa aaagcagaac
     2221 agttttctgc tgataagcag gaactgttcc gctgaatgtg tcttatctat cgagaaaaaa
     2281 tcaatggatt gatatctaag taattcaata catataaaaa gaggacgatc gcattcacta
     2341 aaaaggaaag aatgatgatc ccatagcgaa tggaaacata tttaacaaat acttttgttt
     2401 gaatacgggc atatcttttt cctttatagc tgagcatcat gacaagaagc aaaagggtaa
     2461 tcacaccttg aaaaatcatt ccaataaaca gaattcctga ggtttgataa tttaattgga
     2521 gaaaataagc tgctgccgca actaaatcga ataaaatcgc aataaatggc aaaataatca
     2581 ctcctaacat tgagaataaa taaaagaata acattttttc taaaataagc aaataaaaat
     2641 taaagtaaca aaatagttat gacacaagta aaagaaataa gaataacaat attattttac
     2701 ttatattttg aaacttgtga gagtttgtca ttcgtgctat agttgaaaag taacaaaaat
     2761 aaattttatt tatgatgtac ctttagctca gttggttaga gcagacggct cataaccgtc
     2821 cggtcgtagg ttcgagtcct acaaggtaca taagaggttg tgaaaaagct gccctgcatc
     2881 aagtaataag aacagccaag taaaaacagc ttcttatgtt tttacttggc tgttcttatt
     2941 actgcagatg caagcttttg aataccgttt aaggaagagg ttgtgaaatc agcgttttga
     3001 cctgagtatt agcttaacaa acggaaaaat agttcctcat attttgccgt ttgttaagct
     3061 aataccgagg gtcagctgat tgaacaccat ttaagaaaga ggtcgtgagc ctgccgtttc
     3121 actctgtgtc ataaaaaagc caatctactt tgatagaaaa agcacgtagg actaaaacag
     3181 ttctgcgtgc tttttttatt gtgtgttaaa tatcgtaaat gaagatagat atttttatga
     3241 ttcgacgata gagacgttga aatctttcaa cagctctaaa gcggattctc cgtgttttct
     3301 actggagact aacattggat caacaaaaaa gtctgcttca ggaaaagcac tctgcaggcc
     3361 tatcagatta gagagtacac acaagtttgt ttcaatcccg actacttcga tctctttttg
     3421 ttcttctttg ctttcaaata aagtttcctg gatttcagct aaagtttcag gtggaatcgt
     3481 aaagtaatac tttttaatca ctcgttcatt ttcttgtgga gaaagaagag ggatcaattg
     3541 caaatcttct cgttcttctt ctttgtcctt cagttcaact ggtatatccc gtgtgaagag
     3601 aatatattca ttattttggc gtgctttagc taatctttga gcaatacgtt ctgccaattg
     3661 atctgactct ggaatataaa attcgctgtt tggatcaaga atatgatttt gcatatcaat
     3721 aataactaac attttctttc ctcctacatt catatcgtca ttttattctt tttaatagaa
     3781 gttttttaaa atataagcaa caccagcttc ttcattcgtc agtgttactt ggtttgcaat
     3841 ttcttttact tgtcgctgtg cattccccat cgcaatactc aacccgctgt aattcaacat
     3901 atcaatgtcg ttttcttgat cgccaaaagc catgatgtca ctcgattcga ttccaaggta
     3961 atccgccaga aaaacaagtg aatgagcttt agtgatacct gtaggcgtga tttctaagaa
     4021 atgcggatca gagaatactg attggatacc atctgcttgc agatctcttt gtagcttctg
     4081 tagtttttct tcactcttat ctgttaatgc taatttaaga tagctaagag aaggatcttc
     4141 caacatattt aaaatttgat caaaagaatg gttctgtaaa ttgaaatgtt cataataagg
     4201 gtcatctttg actagatttg attcatcgaa tgtcagctga tcatcttggg tttctcggct
     4261 agcaatgatg gatattttcg cttcttgagc atagaagaag gcttttctca gtgtatcgct
     4321 atctattttt gaacgtctga gaactttcgc catttttcca tccttcattt cagcaatcag
     4381 tgaaccattg gaagaaatca aatagccacc gattcctaat tcggaaaaaa tatctttagc
     4441 agaaatgctg ttccttccgg tagcgacggt tacgattccg ccattttcat caaatttccg
     4501 aagtgcttgg atattttctt ctggtatctt tccatttcga tcaagcaagg taccgtctaa
     4561 atcaatcgct gctagtttca ttttatcttc ctactttctt tttacatatc tattttcctg
     4621 ttaccttaag attaaatgag aatttaaaaa aatgaaacta acttgctttg tcattatgaa
     4681 ttttttcaaa aaacattctt aagaaaaagg tggctatata tagtagtttt tggtcaatac
     4741 ctttgaataa aaagccatga aaaacgaata gttagcgctt accgatgcgt tttgtgataa
     4801 aaaaatttta aaatattcaa tgaaaacaaa gcatatattt tgctttaaaa ccaaatgagg
     4861 aatattctag atgtagaaca ggttagaaaa agattagaaa aaggagtgat tttgatggag
     4921 aagagatacg gcgtagttcc tgtggtaact gcttcagacg aaaattatgc tccttacttg
     4981 agcgtgatga tcgcaactgc attagaaaat tgcaataaaa caagacgcat aaaattttat
     5041 gtgattgacg atggtctatc agaatatagt aaagaaggat tggaagaaac ggtaaataaa
     5101 tattcaagta atgcaagtat ccaattcctg acagtggaaa aagatatcta cgaagacttc
     5161 ctagtcagtg accatatcac aactaccgct tacttaagaa tttctttacc aaacttatta
     5221 gctaaagagg attataagaa agtcctttac ttagattcag atgtgttagt actagacgat
     5281 atcgtaaaac tatatgatga gccgttaaat ggaaaaacaa tcggcgctat tatcgatcca
     5341 ggccaagtga aagctttgga aagattagga atcgattccg atgacttgta cttcaattca
     5401 ggagtgatgg tgattgacat tgatcaatgg aataaaaaag aaattacaga aaaaactatc
     5461 cattacctca gtgaaaatgg cgatcgaatc atctatcacg accaagatgc tttgaatgct
     5521 gtactttatg aagattggga acaacttcat ccaaaatgga acatgcagac ttcgctgatt
     5581 tttgaacgtc atccagcacc aaatgaaaaa tatgaacgtc agtataaaga aggaaatgaa
     5641 aaaccttcga tcgttcactt tacaggacat gataaacctt ggaatacgtt gaaagatcat
     5701 ccgtatacca atttatactt aaaaaaatta gcacacagta ctctaacgaa agtaggcgag
     5761 atcaatgaat aaaaaagaaa tagcagtagt cgcaagttgt aacacaaaat tcgtaccaca
     5821 tttagctgca ttatttgtct cagtattaga taattgcaac ccgtctaaat ttgttcggtt
     5881 ctatgtgatt gacgatgata tcgattttga aagtaaacag cttttacgct tctcagtgaa
     5941 aaacgcacga atgaactcag atgtggaatt cttgaaaatc aataaagaat tctttacaaa
     6001 tgtggtaatc agcgatcgta ttccagaaac agcttattat cgtattgcga ttccggaatt
     6061 gttccgcggc acagaagttg aacgtatctt atatatggat tgcgacatga tcgctttaca
     6121 agatatctct aaattatggc gtcttgactt cggtgattca atcgtagcag ctgttgaaga
     6181 cgctgggttc catcaacgac tggaaaaaat gaaaatttca gctaaatcaa tgcgttattt
     6241 caactcaggt ttgatgctga tcaatgtgaa aaaatggtta gatgaaaata ttacgcaaaa
     6301 agtattagat ttcatcgaac ataatccaga aaaattacga ttccatgacc aagatgcatt
     6361 aaatgctatc ttacatgacc gttggttacc acttcatccg cgttggaatg cacaaggcta
     6421 tatcatggca aaagcaaaaa aacatccaac agcagcaggt gaacgtgaat acgaagaaac
     6481 tcgcaacaat ccttacatta tccatttttc aggacatgtg aaaccgtgga gcaaggattt
     6541 tgaagggcca acgaagaaat attacgaaaa atatgcaggg atgacggctt tccgttgtgt
     6601 agctaaattc cctaaatatc caaaatatgc aaaagttcaa ccaaaaacag atgtagttgt
     6661 taaataatag aagacaacaa ctgaagaggg ggagtaggaa tggaaattac aatgtctaaa
     6721 aatgcagtag agacgttaat tgaaaaggtt ggggaaaata caaaaatcgc actcgcgctt
     6781 atcaatgatt ccgatccatt tctaagggac aaaggtgctt ttgcaaaagg cagctttttt
     6841 caaatcattc cttttgtttc ggaatttgga gaatatgcga ctaaaatcga gcatccatta
     6901 ttggacatct atacatctaa attagagcaa aattatttcg gtaaacgatt gaacatggac
     6961 ttcaacaaac agcttgacag cttttcatta gaaaatgaaa tcgcagtact cgattataat
     7021 atcaaattaa agaactgctt cttcagctaa tagtttcgag aaagtccaaa aaggaggtat
     7081 acattgagat actactttgt ggatgaagaa aagaatgtaa tagaaacaga tgaaaaaaaa
     7141 tataattggc tcgtacttga tagtgcaaag cccgaagaga ttgagcaagc aatcgaagaa
     7201 ttcgagcttc ctgatgatat tttcgtagga accgaatatc cggaagaagt ttctcggatg
     7261 gagcgccttt atgagacgaa actagagcat ccattttctt tggtagtgat taatctagat
     7321 cagtcagata atcgtatcga aaaaaaatta acgccaatat cttttgtact ttccgataat
     7381 ctcttgatta cttgtatcga tagaaaaacc gaatttgtgg atcggctgct gacaaagcat
     7441 ggaaatcatt taaactcgtt tgaaaagatc atcacgtata cattattaga tatttacacc
     7501 cattacgtga aagaactaag agagatgaaa aagcgaattg acgctttgga taaagcagct
     7561 cgtaaaacaa cggaaaatga agaactgtat aaacaggcag atcttgaaag agacatcgta
     7621 tatatcgatc ataccttaag agatcaacgg gaaacaatgg atcaattatg gaattctgaa
     7681 actttcatca aacgtttaga cgatgaacag ctactctatg atgtccattt gagacagcga
     7741 caaacagaaa aaatgatcga gatctatcga gatttattag agagtattgg tgatctattc
     7801 aacgggatga tggacaataa tctaaatcat atcatgaaat atctagattc agctgcatta
     7861 atcatttccg ttccggcgtt gttcgcaggg atttggggaa tgaatacagg aggattaccg
     7921 ggtaaaagtt ctgctctagg ctttatactc gtagtctttg gctctttgat agcagcagta
     7981 gttttaggtt accatttata ccggaaagat tatacaaatt aaagaatcta tttaaaacag
     8041 gtatcaaaca aagaaatttg ttttggcaat acaatttaaa aactaggagg aatacagcaa
     8101 tgacagaacc aaaattaatc gacccgcgaa acttgtacca tacggagaaa tttcctaaac
     8161 aagatcagga tacaccagct ttacagcaga atatgattcc tgttcctgat tgtggagaag
     8221 aatcctatga aggcaataat caactagaaa accgccgtgt actaatcact ggtggagatt
     8281 cagggatcgg tcgtgcagca gcgattgcat ttgctagaga aggggcagat atcgctcttc
     8341 aattcttccc aggagaagaa aaagatgcag aggaagtagc aaaatacgtg aaagttgcag
     8401 gacgtaagat tgtcttacta ccttttgatc ttcgtgacga acaagcacct aaagaaatca
     8461 tagataaagc cgtgagtgaa cttggcgggc tagatacgat ggtactaaac gcaggacagc
     8521 aaatttcttg tcagtctatt gctgagttac cacttgagca agtcaaagac acatttatga
     8581 taaacatcat cgctatgttt gctttagtga aagaagctgt tccgcatatc ccagcaggag
     8641 gagcaatcgt aacaacaact tctgttcaag cattcaatcc aagcgaacat ttattagatt
     8701 acgcagcaac aaaagcttca atcgctaact ttacgatcgg tttagcaaaa cagcttgcac
     8761 ctaaaggaat ccgtgtaaat ggtgtagcac ctggtccaat ctggacacca ttacaactag
     8821 acgaaggaca accttctgat tcgatccctg aatttggtca gcaaagttta ctagaacgtg
     8881 caggtcagcc aggagaatta gcaccagttt atgttttctt agcatcgaat aaagcaagtt
     8941 atgttacagc ccaaatttac ggagtaactg gtggagaagc gatcaactta taagaagttg
     9001 atcgtttcac ccctatgagg aggtgcgaaa atgaataaag gtgtaaaaac gatcggagtg
     9061 atcggaacat tacttttgct atctgtgctt ttgtttgcga tactattaag tgcaacctat
     9121 ccattgcctt ttcagctaga gaagtttcga ttcttttcca tcactaattc atacgtgcaa
     9181 caatatgtat tttggcttgc cgttgcattt gctattttga caattatcac gttacttgtt
     9241 ttcctgtttt atccaaaaac aatcggaaac tttctactga aacatggtga tggggagttg
     9301 acgttggata aaaaagcaat tgaaggaatg gttcgttctc acttgcatga agatgaattc
     9361 atccattcac caaaagtaaa tgtcaaagca acgaaaaaca agatcgccgt caatgtaaaa
     9421 ggggagttga aacgaacttc agcactcatt ggtaaaacag gaacattgat gaaagaaatc
     9481 gaaaatgaag tacaacacat attgggaaca aaagagccag tgaaagtatc ggtgaaatac
     9541 acaggctttg aagaaccagc taaacgaagc aatgaccgca aacgagtaga ataggggggg
     9601 accaaaaatg aaagaactat tttcgacata caagctccct atcatctttg gggtacttgg
     9661 attgatatta gccgttttat ggatcaccgt gggctttttc aagaccttat tgatcttgat
     9721 catggcagcg atcggcgtcg ctatcggttt ttatctgaaa caaacgaaaa tcttagatca
     9781 ctattttaaa tcttaggagg aaacatccat gaataacaat aacaaaaata ataacaataa
     9841 aatgaacaac caaaaaccag tgtctgcaca tccagaccca acgacaccaa accaatcaaa
     9901 tggtgtgaac gatgaaaaga acaaaacagc accagtatct gcacatccag atccagtagt
     9961 ccctaacgtt caacaaggag tagaagagaa gaaacatgat gcagaaaagc atgcacctca
    10021 tcatccagga actccagaat ctaaagttcc agaacaacat gatgcaatcg atccttctaa
    10081 acctgtggaa gagcaaaaac atccttctga ccatgcgaaa gcacaagaaa aacttagttc
    10141 tgaccacaca aacggacaag gaaaacttgg ttctgatcat acaaataacc aaggaaagca
    10201 tgattctgaa caggaagatt caatgcgcgg tgagctgaat tatgaagata aagttgtgca
    10261 aaaaatcatc ggaatcgcaa ttgaacaagt agacggttta ttatctgcaa acggtggttt
    10321 cttctctaat gtggcaggaa aacttgtgaa tacagataat gtaacggctg ggatcgaaac
    10381 agaagtcggt aaaaaacaag tagcagttga tatggatgtc attgtggaat atggcaaaga
    10441 tatcgaaaaa atctttgaag aaatgcaaga agtaatcggc aaagaagtaa aaaatatgac
    10501 acatttagaa gtgatcgaag tcaacgctaa cgtagtggac atcaaaacaa aagaagaatt
    10561 tgaaaaagat caagaaacgg tgcaagacaa agtaactgac gcagcgaaaa aaaccggtga
    10621 atttgcttcg aatcaaacag ataaagtaaa atcagcagct ggaagcggcg cacaaaaagt
    10681 aaaagaaaat acagaaccac gggttcagta ataaggaagt aaaacattag gaggaacgaa
    10741 acatgggatt tatttggtca cttatcgtcg gaggaattat cggagcaatt gcaggagcaa
    10801 tcacgaataa aggttcttcg atggggatta ttgcaaatgt cgtagcaggt ttagttggat
    10861 cagcacttgg tcaagcatta ttaggttctt ggggaccaag tattgcagga atggcaatcg
    10921 tgccatcatt gattggtgcc atcattttag tactaatcgt atcattcttt gctcgaaaac
    10981 tgtaaaaaga cttttaaaaa gaggtcgtga aaaagctgtt cttcatcaag taataagaac
    11041 agccaaacaa aaatagcttc tcatattttt catttggttg ggcatattat cgaagatgca
    11101 agcttttgaa cactgtttat acggaataag aggctgtgac aagacttttg tcacagcctc
    11161 ttatttatgc gggcaaattc ccaattagat ttttaaaagt ttttccttaa atgtgtcttt
    11221 attgatacag agaagcttct ttaataaaac aatgcctccc taaattttct tgagatagga
    11281 aaggtgaaca tacaaaataa tacgaccact ttgaaaaccc agatgatcca caaatggatc
    11341 gtatgatact gatgaagtaa aaagcaatgg atcagaaact caaagagatt gaaaaagaca
    11401 aggaagaaat aatatctctt ttttactctt gtctgtttta gccaataata gctcgtaaag
    11461 taatctagac aaacaaatag aagtaaacaa agtttcgtaa gagcagcaat cgtatcatgt
    11521 tgctctgcta gacgattgac gagcaggaaa aatgttggta atggaatata gatcacgagt
    11581 aatgaaagaa aaaagtaaac aataaatggc atactattcc tcctaattgt gtgagttcgc
    11641 cctcatttta aaataacgat atttgtttgt gaagcttttt cgtgtcgtaa caaatgttat
    11701 ctaatgtatt tttaaataaa taatcattat tatcaaaata atg
//
LOCUS       DAFEKH010000076        11238 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.079, whole genome shotgun sequence.
ACCESSION   DAFEKH010000076
VERSION     DAFEKH010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11238
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.079"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            83..1129
                     /gene="gmd"
                     /locus_tag="LP386_002535"
     CDS             83..1129
                     /gene="gmd"
                     /locus_tag="LP386_002535"
                     /EC_number="4.2.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="HBL1919734.1"
                     /translation="MKKALITGITGQDGSYLADFLLEKGYEVHGITRRASISNTARID
                     HLMGKITLHDGDLSDSSSLIRIISIVQPDEIYNLAAQSHVQVSFDVPEYSGDVDALGV
                     MRILEACRILGLTKKTKIYQASTSELYGKVEEVPQRETTPFHPYSPYAVAKQYGFWIT
                     KEYREAYGMFAVNGILFNHESERRGENFVTRKITLAAGRIAEGLQDHLELGNMDSLRD
                     WGYAKDYVECMWMILQHETPEDFVIATGEQHTVRDFTEKAFAANGMTIRWEGTGIDEK
                     GYDVETGKMLVCVNPQWFRPTDVDNLWGDPTKAKTVLGWNPQKTSYEELVNIMAKHDR
                     ELAKREAAMKNAVK"
     gene            1209..2222
                     /locus_tag="LP386_002536"
     CDS             1209..2222
                     /locus_tag="LP386_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919735.1"
                     /translation="MATLCRCEAKITLVCGANHLDFAKRNLEQELPKELIDRVRYRPI
                     NTDIGLINREGTLLVDTGKLTEICEYFLAKVPSLAKTEAEWLKREAVSAVLCDMPIWA
                     MDACDMAGVPFLYVGNFTWTELYREFLPEHIWKEYAKRYGKIQHTMLYALNNEEMLEF
                     LQNSEKTPTSVVARPIHNDEVQRIKSQHEKPPVFVALGMSARFKQPIDVSHAPYDFIT
                     TLGVPLVGENVTVISNSTPNTQDYIAAADYVITKAGWGTVAECILAQRPMALFARDTV
                     LEDRTTICKLQKLGLAISVTPENLHRVERVIEDLKQLDTSNFDTFYDAASEIADKLIS
                     LMQ"
     gene            2259..3203
                     /locus_tag="LP386_002537"
     CDS             2259..3203
                     /locus_tag="LP386_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014424865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-L-fucose synthase"
                     /protein_id="HBL1919736.1"
                     /translation="MMEKDAKIYVAGHRGMAGSAIVRELNRQDYNNIITRTHKELDLC
                     RQDAVEAFFAQEKPDYVFLAAAKVGGIIANQNALADFMYENMILEMNVINSAWKNGCK
                     KLQFLGSSCIYPRMAPQPMPESCLLTSELEKTNEAYALAKISGLKYCEFLNKQYGTDY
                     ISVMPTNLYGPNDNYHPTHSHVLPALIRRFHEAKEAGLPTVTCWGDGSPLREFLYVDD
                     LANLCVFLMNNYSGDETVNAGTGKELSIKELTEMVAKVIGYEGEILWDTSKPNGTPRK
                     LLDVSKATKLGWTYKTELEDGIRLSYEDFLNNPMRAER"
     gene            3271..4584
                     /locus_tag="LP386_002538"
     CDS             3271..4584
                     /locus_tag="LP386_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBL1919737.1"
                     /translation="MNIVLLSGGSGKRLWPLSNDIRSKQFIKIFKTEDGYESMVQRVY
                     RQIKKVDNDATVTIATSKTQVSAIHNQLGEDVGVSVEPCRRDTFPAIALATAYLVDVM
                     GIDPEESVVVCPVDPYVEDDYFEALKSLSDQADKGEANLVLMGIEPTYPSEKYGYIIP
                     ESAEQTAFVNTFKEKPSEAVAKEYIAQGALWNGGVFVYKLKYVMERAHQLIDFVDYQD
                     LFNKYDTLTKISFDYAVVEHEDKIQVQRFAGMWKDLGTWNTLTEGMEESIIGKGVMNE
                     NCDGVHILNELDVPVLAMGLHDVVISASREGILVSDKEQSSYIKPFVDKFEQQIMFAE
                     KSWGSYKVMDVEAESMTIKVTLNASHSMNYHSHKNRDEVWVVLAGTGKTIVDGYEQVV
                     KAGDVITMSAGCRHTIMADTELKLIEVQLGKDINVKDKQKFELEY"
     gene            4668..5570
                     /locus_tag="LP386_002539"
     CDS             4668..5570
                     /locus_tag="LP386_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase"
                     /protein_id="HBL1919738.1"
                     /translation="MMNLQKELRCLLLRKLGMLYAPGWTELCCVWSEYQGMTLTEVLQ
                     EHPEFLGTHPQTKGELPILIKFIDAKKDLSVQVHPTDEYAIEKENGQLGKTEMWYVLD
                     ASLIYGLQKITEEAVIREAIAQGTVERYLQKVPVKKNDVFFIEAGTIHAIGAGALIAE
                     IQENSNLTYRLYDYDRVDKNGKKRELHVDKALEVANLKGLSEPKQPLRVLKYRAGVAA
                     ELLCRCKHFEVSRMIVNTERRQTVHYRADSVSFRVLLCVNGCGTVRFDNESLDIYKGD
                     CLFVPADSTEISIHGSIQFLDVRG"
     gene            5575..7227
                     /locus_tag="LP386_002540"
     CDS             5575..7227
                     /locus_tag="LP386_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBL1919739.1"
                     /translation="MNYKVEYERWLNHANADIIEELRSYSEKDIEDSFYKNLSFGTGG
                     LRGTIGAGTNRMNVHTVGKASQGLADYLNKNYEAASVVVGYDSRIKSDVFAKTAADIF
                     AANGIQVHLWPELLPVPTVSFATRYLKADAGVMITASHNPSKYNGYKVYGADGCQITT
                     EAATAILAEIEKLDIFADVKMDGDASKIASIQSEVLTAFIEEVKGQSVLFGEKVDKNV
                     AIVYSPLNGTGLVPVTRTLAEMGYSNVTVVEEQRLPDGNFPTCPYPNPEIKEAMSLGM
                     EYAKKYNADLLLATDPDCDRVGIAVKSAHGDYVLLSGNETGLLLLDYICSQRIKHGKM
                     PADPVMVKTIVTMDLGERIASNYGVRTIDVLTGFKFIGEQIGMLEKAGKADSYIFGFE
                     ESYGYLSGSYVRDKDGVNAAYLICEMFSYYKTQGISLLDKLNEIYTKYGYCLNTLHSF
                     EFDGAAGFTKMQEIMVEFHKGLDIIGGKKVIETLDYSKGLNGLPKSDVLKFMLEDNCS
                     VVVRPSGTEPKLKTYISVSAENKEAAEAMEAIMAAELAEMFE"
     gene            7251..8117
                     /locus_tag="LP386_002541"
     CDS             7251..8117
                     /locus_tag="LP386_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1919740.1"
                     /translation="MEELFSNALKSVKSNRVLYTASFFARSSLLYLQEIGQLTALKAH
                     TSRRTGLSSYLCFLVEVGSGTLEYKGQKYTLQVGDMVFIDCLKPYVHESSEDDLWTLR
                     WCHFNGIGMTEVYKKYLERGGQPVFKTSKTDKYADLLRSLHMVAEGQEYVRDMKINVL
                     LSELLMHLMEDSWNPDKVPNFSTKKMELQNIKQYLDDHYTEKITLDQLSAEFFINKQY
                     LAKIFRETYGTTVVGYLNQKRITQAKHLLRFTNLSMEEIATKIGITDANYFSRTFFKV
                     EGVRPSEFRKMW"
     gene            complement(8159..8350)
                     /locus_tag="LP386_002542"
     CDS             complement(8159..8350)
                     /locus_tag="LP386_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919741.1"
                     /translation="MIIRDDHIYTCDSCHYSFPADEQPERCPDCGKTATRLDTEIETE
                     DYYRVRAEIKAEIKALNAG"
     gene            8380..8919
                     /locus_tag="LP386_002543"
     CDS             8380..8919
                     /locus_tag="LP386_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919742.1"
                     /translation="MQLLLYRIGDSTKIRFLINVRFRVIYSTVLPKGIPQRQKWMIHM
                     EEIMQMILGNAKFQLGQVVSTPAVLETFNPLQTANGIPEALSNLWFRQEISIAEIEDA
                     VLDAKNGKELANSLNRIKLFRKFTLDRELDGMVRLKGADVWKNISYLKVYTATPPKKP
                     TPPRFQSNGWSLFFSHKSA"
     gene            9047..9400
                     /locus_tag="LP386_002544"
     CDS             9047..9400
                     /locus_tag="LP386_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919743.1"
                     /translation="MAMSEKAKKYLKEIKGAKTIPELKDVEIAIKRDGILAWAEFTKL
                     NEAVEEKKVALRKKKQETSLQEILFWAYKKESDKLLKMMDEGADKDAIQMQVQRYDSI
                     GQIIAEADLEDEYEV"
     gene            9867..10343
                     /locus_tag="LP386_002545"
                     /pseudo
     CDS             9867..10343
                     /locus_tag="LP386_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290865.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
     gene            10343..10537
                     /locus_tag="LP386_002546"
     CDS             10343..10537
                     /locus_tag="LP386_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919744.1"
                     /translation="MAETRPKGYPKLKEYTPNRFMLSECHYDKARADRAVNFIGQLRH
                     TKGKWAGNRFWLLPWQEQII"
     gene            10543..10828
                     /locus_tag="LP386_002547"
                     /pseudo
     CDS             10543..10828
                     /locus_tag="LP386_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311319.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
     gene            10842..11208
                     /locus_tag="LP386_002548"
                     /pseudo
     CDS             10842..11208
                     /locus_tag="LP386_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387104.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
BASE COUNT         3153 a         2303 c         2855 g         2927 t
ORIGIN      
        1 ttatcgtgta ttcttgaaaa gtattagaaa ttacgagcca tttatatggt cttatcactt
       61 acataggaaa ggataatgta tcatgaaaaa agcgctgatt actggtatta ctggtcagga
      121 cggttcctat ctggcagatt tcctgctaga gaagggctac gaagttcacg gtatcactcg
      181 ccgtgcttct atttccaata ccgctcgcat tgaccatttg atgggcaaga tcacccttca
      241 tgacggtgac ctgtccgact catcttctct gattcgtatc atcagcattg ttcagcctga
      301 tgaaatctat aacctcgctg cacagagcca tgttcaggtt tcttttgatg ttcctgagta
      361 ctccggcgat gttgatgctt tgggcgttat gcgtattctg gaagcttgcc gtattctggg
      421 cctgacgaag aagactaaga tttatcaggc atctacttct gagctgtatg gcaaggttga
      481 agaagttcct cagcgtgaaa ccactccgtt tcatccttac agcccttatg ctgttgcaaa
      541 gcagtatggc ttctggatca ctaaggaata tcgtgaagct tatggcatgt tcgctgtcaa
      601 cggtattctg ttcaaccatg aatccgaacg tcgcggtgag aatttcgtca cccgtaagat
      661 caccctcgct gccggccgca ttgcagaagg cctgcaggac catctggaac tgggcaacat
      721 ggactccctg cgtgactggg gctatgcaaa ggactatgtt gagtgcatgt ggatgattct
      781 ccagcatgag actcccgagg acttcgtgat cgctaccggc gagcagcaca ctgttcgtga
      841 cttcaccgag aaggcattcg cagcaaatgg catgaccatt cgttgggaag gcactggcat
      901 tgatgaaaag ggctacgatg ttgaaaccgg caagatgctc gtttgtgtaa atccacagtg
      961 gttccgtccg actgacgttg acaacctgtg gggcgacccg actaaggcaa agaccgttct
     1021 cggttggaat ccgcagaaga cctcttacga ggaactggtt aacatcatgg caaagcatga
     1081 ccgtgaattg gcaaagcgcg aagctgcaat gaagaacgca gtcaagtaag ctgacattga
     1141 ataaacatat ctgtttctat ctttccagtc acggcttcgg acatatcgcg cggaatctgc
     1201 ccattattat ggcaacactc tgccgatgcg aagcgaagat tacactggtt tgcggcgcaa
     1261 atcatctgga ttttgcaaag cgcaatttgg agcaggaact gcccaaagag ctgatagacc
     1321 gcgtgcgcta tcgtccaata aacacagata tcggtctgat taaccgtgag ggcaccctac
     1381 tggtggacac gggtaagctg accgagatct gtgaatattt tttggcaaag gttccttctt
     1441 tggcaaagac agaagccgaa tggctcaagc gagaagctgt cagcgcagtg ctttgcgata
     1501 tgccaatctg ggcaatggat gcctgcgata tggcaggagt acctttcctg tatgtaggaa
     1561 acttcacttg gacagagctg tatcgcgaat ttttacccga acatatttgg aaagaatatg
     1621 ccaagcgtta cggtaaaatt cagcacacca tgctttatgc gctaaataac gaagaaatgt
     1681 tggaatttct ccaaaacagc gaaaaaacac cgacttccgt tgtggcgcgt ccgattcata
     1741 acgacgaagt gcaacgcatt aaatcacagc atgaaaaacc gcctgtattt gtcgcactcg
     1801 gtatgtccgc gcggttcaaa cagccaattg atgtcagtca cgcgccgtat gatttcatta
     1861 caacgctagg tgttccgctt gtgggagaaa acgtaaccgt tatttctaac agcaccccca
     1921 atacacagga ctatatagcg gcggcagatt acgttattac aaaggctgga tggggaactg
     1981 ttgcggagtg tattctcgca cagcgtccga tggcactgtt cgcccgcgat acagttttgg
     2041 aagatagaac aactatttgt aaattgcaaa aactgggtct ggcaatttcc gtcacaccgg
     2101 aaaacctcca ccgcgtagag cgggtgattg aggacctcaa acagctagac acctcaaatt
     2161 ttgatacatt ttatgatgct gcgagcgaaa tcgcagacaa attgatttct ctcatgcaat
     2221 gagagatgct ctaaatttag aaaggagcaa gcattattat gatggaaaaa gacgcaaaaa
     2281 tctacgtagc cggtcatcgt ggcatggctg gttccgcaat cgtgcgcgag ctgaaccgtc
     2341 aggactacaa caatattatc acccgcaccc ataaggagct tgacctgtgc cgtcaggacg
     2401 ctgttgaagc atttttcgca caggaaaagc cggattatgt atttctcgct gctgcaaagg
     2461 ttggcggtat tatcgcaaac cagaacgctc tggcagactt catgtatgaa aacatgattc
     2521 tggaaatgaa cgtcatcaac tccgcatgga agaatggctg taagaagtta cagttcctcg
     2581 gttcttcctg tatctatccg cgtatggcac cgcagccgat gccggaaagc tgtctgctga
     2641 caagtgagct ggaaaagacc aacgaggctt atgcactggc aaagatttct ggcctgaagt
     2701 actgtgagtt tctaaacaag cagtacggta ctgactatat ctctgttatg cctactaacc
     2761 tgtatggacc taacgacaac tatcatccta ctcacagtca tgtgctcccc gctttgattc
     2821 gtcgcttcca tgaggctaag gaagcaggtc tgcctactgt tacctgctgg ggtgatggtt
     2881 ctcctctgcg cgaattccta tatgttgacg atctggcaaa cctgtgtgtg ttcctgatga
     2941 ataactatag cggtgacgag actgttaatg caggtactgg caaggaactg tctatcaagg
     3001 aactgaccga gatggtagca aaggttattg gttacgaagg cgagattctg tgggatacca
     3061 gcaagccgaa cggtacacct cgtaagctgc tggatgtttc caaggcaacc aagctgggat
     3121 ggacatataa gactgagttg gaagatggca tccgtctgtc ctacgaggac ttcctgaata
     3181 acccgatgcg tgctgaacgc taatttaccg aggttgctgt gatttttgag gattgcagca
     3241 gcctctttct tataaaaagg agagatcatt atgaatattg ttttactgtc tggcggttct
     3301 ggtaagcgcc tttggccgct gtctaatgac atccgttcca agcagttcat taagattttc
     3361 aaaactgaag atggatatga atccatggtt cagcgtgtct accgccagat taagaaggta
     3421 gataacgacg caactgttac gattgcaacc tctaagacac aggtttctgc tatccataac
     3481 caacttggtg aggatgtggg tgtatctgta gagccttgtc gccgcgatac cttcccggca
     3541 atcgcattgg ctaccgctta tctggtagat gtgatgggca ttgatccaga agagtccgta
     3601 gttgtttgcc cggttgaccc ttacgtagaa gatgactatt ttgaggccct gaaatctctg
     3661 tccgatcagg ctgacaaagg cgaagctaat ctggtgctca tgggtattga accgacttat
     3721 ccttccgaga agtacggcta catcattcct gagagcgcag agcagactgc tttcgtaaat
     3781 accttcaagg aaaaaccttc tgaggctgtg gcaaaggaat atatcgcaca gggtgcactg
     3841 tggaacggtg gtgtgtttgt ctacaagctg aagtatgtca tggagcgtgc acatcagctg
     3901 attgactttg tagattatca ggatctgttc aacaaatacg atactctgac taagatttcc
     3961 ttcgactatg ccgttgttga gcatgaggac aagattcagg tacagcgttt tgctggtatg
     4021 tggaaggatc tggggacttg gaatactctg accgaaggta tggaggaatc cattatcggt
     4081 aaaggtgtta tgaatgagaa ttgcgatggc gtacacatcc tgaacgaact ggatgttcct
     4141 gtgttggcta tgggtctgca tgatgtggtc atctctgcat ctcgggaagg tattctggtt
     4201 tccgataagg aacagtccag ctatattaag cctttcgttg acaagttcga gcagcagatc
     4261 atgttcgcag agaagtcttg gggtagttat aaggttatgg atgtagaagc agagagcatg
     4321 accattaagg ttactctgaa tgctagtcac tccatgaatt atcacagcca caagaaccgt
     4381 gacgaggtgt gggtggttct ggccggtact ggtaagacca tcgtggatgg atatgagcag
     4441 gttgttaagg ctggcgatgt gatcaccatg agtgctggct gtcggcatac cattatggca
     4501 gatactgagc tgaagctgat tgaagtacag cttggcaagg atatcaatgt taaagataaa
     4561 cagaaatttg agttagagta ttaaaaaacg gaggagggct cgttatacag aaaccgtttt
     4621 tattgaagcc ttccgcaaag gattatctgt gggggggaac cgcctgaatg atgaatttgc
     4681 aaaaggaatt gagatgtctc ctcttgcgga aacttggaat gctctacgca cccggatgga
     4741 ccgagctttg ttgtgtctgg tcagagtatc aggggatgac cttgacggag gtgttgcaag
     4801 aacacccaga gtttctggga acgcatccgc agaccaaagg agaattgccg atcctgatca
     4861 aattcattga tgcgaaaaag gatttgtctg ttcaggtaca tcccacagat gaatatgcaa
     4921 ttgaaaaaga aaacgggcag cttggaaaga cagagatgtg gtatgtactg gatgccagct
     4981 taatctatgg gctgcagaaa ataacagaag aagctgtgat ccgtgaagcg attgctcagg
     5041 gaactgttga gcgttatctt cagaaggttc cggtcaaaaa gaatgatgtg ttctttattg
     5101 aggcgggaac gattcatgcg attggtgcgg gtgcactaat tgcagaaatt caggaaaatt
     5161 ccaatctgac ttatcgtctc tacgattatg accgtgttga caaaaatggt aaaaagagag
     5221 aacttcatgt agacaaagcg ctagaagtag cgaacttgaa agggttgtca gaaccgaaac
     5281 agccgcttcg tgttctaaaa tatcgtgctg gtgtagctgc ggaattgctt tgcagatgca
     5341 agcatttcga ggtctctcgt atgattgtca acactgagag aagacagacg gtacactatc
     5401 gtgcggattc agtcagcttc cgtgtgttgc tgtgtgtcaa tggctgtggt accgttcgat
     5461 ttgataatga atcgttggac atctataagg gggactgcct ttttgtgccg gccgattcta
     5521 ctgaaatcag cattcacggg tcgattcagt ttctggatgt gagaggataa taatatgaat
     5581 tataaagtag aatatgagcg ttggctgaat catgccaatg cagatattat agaagaactg
     5641 cgttcctatt ctgagaagga cattgaggac tctttctata aaaatttgtc tttcggtact
     5701 ggtggtctgc gtggtaccat cggtgcaggc actaatcgca tgaacgtaca caccgtaggt
     5761 aaggcaagcc aaggtctggc agactatctg aataagaact atgaagccgc ttccgtggtg
     5821 gttggctatg attcccgtat caaatctgat gtgtttgcaa agactgccgc agacatcttt
     5881 gctgcaaatg gtattcaggt gcacttgtgg ccagaactgc ttcctgttcc tacagtatct
     5941 tttgcgactc gttatctgaa ggcagatgcc ggtgttatga ttacggcatc tcataaccct
     6001 tctaaatata acggctacaa ggtatacggt gcagacggct gtcagattac taccgaggct
     6061 gctactgcaa ttctggcaga aatcgaaaag ctggacatct ttgctgatgt aaagatggat
     6121 ggcgatgctt ctaagattgc atccattcag tcggaagttc tgactgcttt catcgaagaa
     6181 gtgaaggggc agtccgtcct gtttggcgaa aaagtggaca agaatgttgc tatcgtgtat
     6241 tctcctctga atggtaccgg tctggtgcct gttacccgca ccctggcaga gatgggatac
     6301 agcaatgtga ccgttgtgga agaacagcgt ctgccggacg gtaatttccc gacttgtcct
     6361 tatccgaacc ctgaaattaa ggaagctatg tctctgggta tggagtatgc caagaagtac
     6421 aatgcggatc tgctgttggc cactgaccct gactgcgacc gtgttggtat cgcagttaag
     6481 agcgcacatg gtgactatgt tctgttgtct ggtaatgaga ctggtctgct acttctggac
     6541 tacatctgtt ctcagagaat taagcatgga aaaatgcctg ctgaccctgt gatggtcaag
     6601 accatcgtca ccatggattt gggtgaacgt atcgcatcca actatggtgt tcgtaccatc
     6661 gatgtgctga ccggctttaa gtttatcggt gagcagattg gtatgttgga aaaggctggt
     6721 aaggctgaca gctatatctt cggctttgag gaatcttacg gctatctgtc cggtagctat
     6781 gtccgtgaca aggacggtgt taacgctgct tatctaatct gtgaaatgtt ctcttactac
     6841 aagactcagg gtatcagcct gctggataag ctgaatgaga tttatacaaa gtatggctat
     6901 tgtttgaaca ccctgcattc cttcgagttt gacggtgcgg caggttttac caagatgcag
     6961 gaaattatgg ttgaattcca caagggtctc gatataattg gtggtaagaa ggttattgaa
     7021 actttagact acagtaaggg cctgaatggt ctgccgaagt ctgatgtttt gaagtttatg
     7081 ctggaagata actgctctgt tgtggttcgt ccttctggta ctgagccgaa gctgaagacc
     7141 tatatcagcg tcagcgcaga gaacaaggaa gccgccgaag ctatggaagc tattatggct
     7201 gctgaactgg cggaaatgtt cgagtaagaa aagaaaggag aaatcttgta atggaggaac
     7261 tgttttctaa cgctttgaaa tcggtgaagt caaatcgtgt gctgtacacg gcatcgttct
     7321 ttgcaagatc ctctcttttg tatttgcagg aaattggaca gctgactgct ctgaaggcac
     7381 atacatctag gcgtacagga ttgtcatctt acctttgttt cctggtagaa gttggttcag
     7441 gcacattgga gtataagggg cagaaatata cgcttcaagt aggagatatg gtgtttattg
     7501 actgtttgaa gccgtatgtc catgagtcat cagaagatga tttgtggact ttgcggtggt
     7561 gccattttaa tggcattggt atgacggaag tctacaaaaa ataccttgaa cgaggtggtc
     7621 aaccggtctt taaaacatca aaaacagata agtatgctga cttgctgagg agccttcata
     7681 tggtggcaga gggacaggag tatgtccggg atatgaaaat caatgttcta ctcagtgaac
     7741 tgctgatgca tttgatggaa gattcttgga atcctgacaa agtgccgaat ttctctacaa
     7801 aaaaaatgga attgcagaac ataaaacaat atctggatga ccattacacg gagaagatta
     7861 cgctggatca gttgagtgca gagtttttta tcaataaaca gtacttagct aagatttttc
     7921 gtgaaactta cggtacaact gttgtcggtt atctgaatca gaaacgaatc acacaggcca
     7981 agcacttgct acgctttaca aatctaagta tggaagagat tgcaacaaaa attggcataa
     8041 cagatgcaaa ctatttttcc agaacttttt tcaaggtgga aggtgttcgt cccagcgaat
     8101 tccgcaagat gtggtaataa aaagccggcg gtgttgagcc gccggtcagt acctgtcgtt
     8161 aacccgcatt caaagcttta atctcagctt tgatttcagc acgaacacga tagtaatctt
     8221 cagtttcgat ttcggtatcc agccgagttg ctgtctttcc gcagtcagga caacgctctg
     8281 gctgttcgtc ggcagggaag ctgtagtggc aggaatcaca ggtgtaaatg tgatcgtcac
     8341 gtataatcat cacctaccaa tccagtgctt agatttttca tgcaattact attatatcga
     8401 attggtgatt ccacaaaaat ccgcttcttg ataaatgtac gattcagagt gatatatagt
     8461 actgtactgc caaagggaat accacaacgg cagaaatgga tgattcacat ggaagaaatt
     8521 atgcagatga ttttagggaa cgcaaaattc cagctcggac aggtggtttc gacccctgct
     8581 gtattggaaa ctttcaaccc cctgcagacc gcaaacggca ttcccgaagc cttgagcaac
     8641 ctttggttta gacaggaaat tagtattgcg gagatcgagg acgcagttct ggatgccaag
     8701 aacggcaagg agctagcaaa cagcctcaac cgcatcaagc ttttccgcaa gttcaccctc
     8761 gaccgagagc tggacggcat ggtcagactg aagggcgcgg acgtctggaa gaacatcagc
     8821 tacctcaagg tctacaccgc cacgccgcct aagaaaccga cccccccaag gttccagtcg
     8881 aacggctgga gccttttctt ctctcataaa tcggcataat gtatacaaat acagctccaa
     8941 atgattgtgt agtatatgcc tgtggattga cttgatatag tcgagagact atggcaatat
     9001 acacacaacc aaaggggaaa atcccaaaaa caaggaggaa acgctaatgg caatgagcga
     9061 aaaggcaaag aaatatttga aggagatcaa gggtgcaaag accatcccgg agctgaagga
     9121 tgtggagatc gcaatcaagc gagacggtat ccttgcttgg gcagagttca ccaagttgaa
     9181 cgaggcggtg gaagagaaga aggtcgccct tcgcaagaaa aagcaggaga ccagccttca
     9241 ggagatcctt ttctgggcct acaaaaagga atcagacaag ctgctgaaga tgatggacga
     9301 gggagcagac aaggatgcca tccagatgca ggtccagcgt tacgacagca tcggccagat
     9361 cattgcagag gcagacctcg aagatgagta tgaggtttga gaatacagcc tgaaccacta
     9421 agaaccaaat accgaaaggg acttctgaaa cagacagagg tccctttctt ttgctcactt
     9481 tggcggtcaa ttatgaacca aaaaccagtc gaatgattgt gtacattatg gctttcaaac
     9541 gacttgataa taatcacttt tagagtgata tatgtactac aaaaaacaaa agactggaga
     9601 aaacaacaga tgagcgaata cagaatcatt tatatcagcg acgaggacgg cggcgaggtg
     9661 gaaggatgtg gctacacggc tacgatggtt atgatgcggt cagaaacttc ttggaatttg
     9721 cctgcggcat cttgaaaatc ctgcgggtgc gattcatcag aagagtggac tgaaatacaa
     9781 gttagcagat agagaagaga gtcaggtttc gacttggctc tgttctctgt ctactggcag
     9841 aaatacattg aagggaggtg acgactgtgg caaccagagg aagaaaatca accccgacag
     9901 ccatgaagaa gctggaggga aatccgggca atcgcccact caatgcaaaa gagtcaacgc
     9961 cggaaaagaa ggcaccgacc tgtccgaagt ggctggaacc agaggcaaag aaggaatgga
    10021 agcgtctggc aaagcagatg gaggccatcg gaatcttgac agatgtggat atggctgcct
    10081 ttgccggtta gtgccaagcc tacgcccgct ggaaggaagc cgaggaattc attacccagc
    10141 acggtatcat cgtgaaaacc ctatccggct attggcagca ggtaccacag gtgtttattg
    10201 cccagaccta tctgaaaatt atgaaccgat tttccgagca gttcggtctg acgccttcgt
    10261 ccagaagccg tatcattgcc ggtgatggcg gtggtgtcgg agcagaagat gcgatggagg
    10321 ctctgttggg aggtggtagc tgatggcaga aaccagacca aagggctatc ccaaattaaa
    10381 ggaatacaca ccaaaccgat tcatgctttc ggaatgtcac tacgacaaag ccagagcgga
    10441 tcgggcggtg aactttatcg gacagctccg acacaccaaa ggcaaatggg caggcaaccg
    10501 cttctggctc ttgccttggc aggaacagat catctagtgt aatctcgctt aactgtatta
    10561 acggacgtag cgactttatt aagagtgttc atggtaggag cattagttgc aacaatgatt
    10621 gatattaaat ttttatggta ccaacgattg gcgatgtgac attgaatatg caaaactata
    10681 tcgatatgat attatctaaa atcttactcg ctgggatcgt cgaggtgttt attggttgtt
    10741 aggaaagaaa aatatgaccc aactcgagcg atttttatcg tattacttgt gtgtggcttt
    10801 atctgcattg tgtgtgattt cgaaataagg gagagccaaa aatgagtaga aaattgatat
    10861 tgattagtca cggaaaattt tgtgaggaat tgaaaaaaag tacaaaaatg attatgggac
    10921 ctcaagagaa tatctacacg ttacctttat taccagaaga tggcactgaa acatacagac
    10981 aaaagctctt actgtcatag attcgttaaa tgattttgtg gtactatgcg atcttttagg
    11041 cggtacacct actaatatca tttctaaact gataatggaa ggacaacaga ttaaacttta
    11101 tgtcggatta atcttcctat ggtcattgaa tttatcaact cgcaagtgat tggttcagag
    11161 cccgagtttg ttcgtgcagg atgtgaaagc attgtatctg tcaactaatt aattagtgga
    11221 atagtagaag atgaagag
//
LOCUS       DAFEKH010000077        11126 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.080, whole genome shotgun sequence.
ACCESSION   DAFEKH010000077
VERSION     DAFEKH010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11126
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.080"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..370
                     /locus_tag="LP386_002549"
     CDS             <1..370
                     /locus_tag="LP386_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL1919745.1"
                     /translation="FVGDDYMKVLPKFSSGSACIVKYAVEDLPEAYPEVMTANCDDNP
                     WIIRKRHGGVVPACEEQGRPLKPLPFKAAVYVLGTGDNHSLYGKTTKYQTKMREILEM
                     FIAKRKIKGKLKAEFSVDWL"
     gene            357..1487
                     /locus_tag="LP386_002550"
     CDS             357..1487
                     /locus_tag="LP386_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBL1919746.1"
                     /translation="MIGYKVSIMKVLMCESQMPENWYSFDLSKELNQYVDLTLLCKRD
                     VPPLDPKIKSKHILYHKSTNKVFSALVFLKSLFLIWKEIRFGDYDIVHLQLMKSLKYE
                     GGLYVLCKRHYKKLIMTVHNVLPHEVREKDRQEHFNIYSNCDGFIVHNRVTEQHLYAE
                     FPELNAKSYVCPHAIYGDVKHISRAYDKDKFEFILFGQIRPYKGIDVLLNAITELPMD
                     VRKKVHFTIAGQQHPKQDSTDYKKMIEDLKVSDCVLYKPERISDEEMDSMFRNADAAI
                     FPYKEIYGSGALLMAYTYCLPTIVSNVPAFMEETEEGKIGLLFENLNSKSLADTIVKY
                     VNLSPAEKSKIEDDIYELVNRKYTWAASAKLTYEAYKQILNE"
     gene            1518..2753
                     /locus_tag="LP386_002551"
     CDS             1518..2753
                     /locus_tag="LP386_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919747.1"
                     /translation="MQISKWKIIQFLMVFLMIISSSILKPLGGWLGETMNVRLVTVIL
                     AIVCLLIASLPAFRKNRYLNFCTLLICVVIIAAYIYSDKTIWVKSRESMSLYYVLLAY
                     PLFCTLINQAWNLDSMLNTICGVTFLSYILRTSISLIQKFSGVLLYENIYRECAPENW
                     YRGGFLRINPPCFTIIIIPIALYMIERQVVARRKVKYYLLIASALAYSAVIHGSRSVL
                     VYQIIVLGCYILFKKGSSKRKIAMWVLAGLLVVIFINSTMFSTFVETFTNSTGEYAGS
                     AESRFASVWFFVPKFLQSPLFGTGILTGEEFTFILPGGVRGHLSDIGFFYTITQYGVG
                     ILIFDILFIIKGFKTALLASKVGMTGYQYLAFGITLSVLLTGINIDWFYPIFTPAIPV
                     CLAVIEYIYQECRSVANIE"
     gene            2778..3887
                     /locus_tag="LP386_002552"
     CDS             2778..3887
                     /locus_tag="LP386_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919748.1"
                     /translation="MNKKEILYNILKKYENLPYVFRNMFGHNISKLVSWKLTADCATV
                     EENSEVYAAFQLRSKDMSDVPVMGLVNCCKDVAIVMQGPLCLKDDFSYNTLAYYKKCY
                     PNALIILSTWKDEDIKALKRIEDLGVIVICSEKPEKPGHLNINYQVGNTLPGIVRAKQ
                     LGAKYVCKTRTDQRIYHPNAMAFFCSLLEQYPVNNEDDWKLIQNQRLLLLSMPYGDMF
                     FPYCLSDFLYFGDVDDMINLFSIPSDVREKGAVSRGVSRREISENNLAPEVQLLRSYI
                     SRMGGNEECSIRAYWEFVKNHVITINKNQIDLYWHKYVGRYSNNTIYGTYYIDDSQDA
                     LHCYNFDFINWLNLYTGKYEYKAKYEKYMDFVWEE"
     gene            3929..5263
                     /gene="gmhB"
                     /locus_tag="LP386_002553"
     CDS             3929..5263
                     /gene="gmhB"
                     /locus_tag="LP386_002553"
                     /EC_number="3.1.3.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-glycero-beta-D-manno-heptose 1,7-bisphosphate
                     7-phosphatase"
                     /protein_id="HBL1919749.1"
                     /translation="MKTVIMAGGRGSRISELFPDIPKPMIPIDGIPVLERELCSLRDQ
                     GFNDIILTVSYLHEKIEEHFGDGSKLGIKIKYFIEKTPLGNAGALYFLLDELGDEPFL
                     LLNADAVFDVDFRQMIRFHVENNADVTLFTHPNSHPYDSGLIISDDNKKVLQWLAKED
                     QRPEYYKNRVNAGLHVINPKVLRENPLMEIVNKSIVEGGGLPYKIDLDRMILKPLANT
                     GRMYCYDSPEYVKDMGTPDRYRAVIKDFQKGIIVGKNLSNPQKAIFLDRDGTINKYVG
                     FLRNAEEFELIDGVSEAIKIINSLGFLCIVITNQPVIARGEVTVDELNSIHNKLETML
                     GHAGGFLNGIYYCPHHPHKGYAGEVIELKIDCNCRKPKPGLLLEASKDFNINLSQSFM
                     VGDSESDVIAGKNAGCKTVLITEDITLPANYGQDYSVCSLLEFVKNHLCTMQ"
     gene            5298..6935
                     /locus_tag="LP386_002554"
     CDS             5298..6935
                     /locus_tag="LP386_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HBL1919750.1"
                     /translation="MKVLIPAAKVVEKELQSIGMLPAIIYPINKKIVFDYLYNQYNAI
                     CDSLDIICYEKADKVHRRLKNYHDSRIHICDLPELGDLGQTVYFGLSDEDEPVLINFA
                     DTIVMESMSDIEMDTFYYSEDFVSSTWTYFKINEGIITDIHDKEEAYVSDKREKLFIG
                     VFMFSSSKLLKSCLREAVESRKQGGINSFYRALQLYSERCPLKAVRTEKWFDIGHIDK
                     YYNTKLEVKAREFNHISIDKDRGILKKTSDDKDKFIGEIKWYLKLPADIEYVRPRIFD
                     YSTSYVAPYVDMEYYAYHTVHELYLYGDLKYNQWHDLFSRIKFICSDFKRYTLKDEKI
                     RESLEDMYLRKTMQRFQKLSEDKRFSAFFEKQIQINGRKFISLTGVIELLKNLIPSML
                     YDVNEFCIIHGDLCFANMMVDSNCSFVKVIDPRGKFGKYDIYGDSRYELAKLFHSLDG
                     KYDYIIKDLFTVEYDTECAVIDYTINTRVRDYDLFELFKSVFSDEIKDDFDKIVLIEA
                     LLFLSMIPLHGESFDHQIVMLATGMELLARVSNKVIL"
     gene            7037..7432
                     /locus_tag="LP386_002555"
     CDS             7037..7432
                     /locus_tag="LP386_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HBL1919751.1"
                     /translation="MYSEYSFVFDIDGTLCPIKKKDERYEDLVPYENMVEKLRFYKEN
                     GAKITLFTSRNVNSYKGNLGMINANTAKVLLAWLDKWDIPYDEILYGKPWPGHKGFYV
                     DDRTVRPDEFLRCSVDELNEICNSSKKRF"
     gene            7450..8181
                     /locus_tag="LP386_002556"
     CDS             7450..8181
                     /locus_tag="LP386_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL1919752.1"
                     /translation="MEKKMTVIITMAGLGSRFRKIGYAVPKYMINAKGRTLFDWAMDS
                     LVGYNKNVDKYIFVVRQEDNASAFIKEHCAYFGIENVEVIEIDYMTDGQATTCMLAIP
                     YCNQDNEIMVYNIDTYVESNEMKYEDICGDGHIPCFHADGDHWSFAKLNDRNEVIEVR
                     EKVRISDNCTLGAYYFSSAKLYKALYEEYYADSSNMEKNEKYIAPLYNFMIKKGLKVT
                     ISIVDAKKVHVLGTPEELNVFLNQE"
     gene            8205..9656
                     /locus_tag="LP386_002557"
     CDS             8205..9656
                     /locus_tag="LP386_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HBL1919753.1"
                     /translation="MTSNNLIVKTLSRYKNTPLPVKAALWFMVCGFLQRGVSMITTPI
                     FTRVLSTEQYGLYSTYLSWESLLLMITSLSLFKAMMNLYVKYDNQEHILSTVSGLTLV
                     LTIFWFVIAIFIKDILAEILGLTPVLVVCMFSYFIFQAEIQCWSLHKRYIYDYKTLLV
                     ATLAVTVGSSVVGCLAVLFISPTAEARALMNVLVTGVVGVAVYISVFRRCKDFKDNEV
                     WNFAVVFCVSLMPHYLSEFILNGSDKIMINYLCGSSDVAIYSVAYSIGALINLVTNSV
                     NSTFAPYQYQKIKSGEYDLLSKRANEVLGLVAAMLFALMLFSKEIVLIFGGQKYIDSV
                     NLIVPICIGIYFNYMFQLFARVQEYFEKKLTVVIPSVLCAIMNIVLNYVFIKLYGYQA
                     VAYTTVFSYMFFCVIHYIFYRKVCKELLDGKNIYDVRGILLISAITIAGGILISIINK
                     FDFIKYLIIAIACVAAIIFRKRLLLLVRRIMSK"
     gene            9682..10293
                     /locus_tag="LP386_002558"
     CDS             9682..10293
                     /locus_tag="LP386_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBL1919754.1"
                     /translation="MIDIISAIMVNVLTALYQPFLFAVLTAYLFMYWYLFIVDNSRDP
                     KNLKDSVLIWLRYFKASSKFRRLFFLAFYFTLILFKTLLNRNMWMNPLSNVIGQWSLY
                     IIDNATGESRLTTECVENTMLFIPFCMLLLWWRDIKCDIIRTIYVGIKYVFLFSLSIE
                     FTQLFFRLGTFQLSDLFYNTLGGLIGALLYWLFYRLNKYIDLK"
     gene            10475..10990
                     /locus_tag="LP386_002559"
     CDS             10475..10990
                     /locus_tag="LP386_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HBL1919755.1"
                     /translation="MVVVMVKVFDIIKFSDFRGYTAVALDNETLFSIGIEFHIKQINQ
                     GFSHNKYTMRGLHYQSGEHAQGKIVMCLHGEIMNIALDIRQGSSTYGCVYVNTLSESN
                     GKCAYIPRGYAHGYLTMEDNTLVQWCVDNDFNSNAAKCISYESVDIEWPVSRQCFVIS
                     EKDKNGERLSF"
BASE COUNT         3676 a         1464 c         2265 g         3721 t
ORIGIN      
        1 ctttgttgga gacgattata tgaaggttct accaaagttc tcatcaggaa gtgcgtgtat
       61 agtaaaatat gcagtggaag acctgcctga ggcatatccg gaagttatga cagcaaattg
      121 tgatgataat ccatggatca ttagaaaacg acatgggggc gttgttccag catgtgaaga
      181 gcaagggcgt ccattaaaac ctcttccatt caaagcagca gtatatgtat taggaacagg
      241 ggacaatcac tcgctttatg gtaaaacgac aaaatatcag acgaagatgc gagagatact
      301 ggaaatgttt atagcaaaac gtaaaattaa aggaaaactg aaagcagaat tttctgttga
      361 ttggttataa ggtgagtatt atgaaggtat tgatgtgtga aagccaaatg ccagagaatt
      421 ggtattcgtt tgatctttct aaagaactta atcaatatgt tgatttaaca ttgctgtgta
      481 agcgtgatgt tcctccttta gatcctaaaa ttaagagcaa acatattttg tatcataaaa
      541 gtacaaataa agtgttttcg gcacttgttt ttctgaaaag cttgttctta atttggaagg
      601 aaataagatt tggtgattat gatattgttc atttgcaatt gatgaaaagt ctcaaatatg
      661 aaggcggatt gtacgtttta tgtaagagac actataaaaa attaattatg acagttcata
      721 atgtgttacc acatgaggtt cgtgaaaagg atcgccaaga gcactttaat atatattcaa
      781 attgtgatgg tttcattgtt cacaatcgag taacagaaca gcatttatat gctgaattcc
      841 cagaattaaa tgcaaagtca tatgtttgtc cacatgctat ctatggagat gttaaacata
      901 tatctagagc gtatgataaa gataagtttg aatttatctt gtttggacaa attcgtccat
      961 ataagggaat tgatgtactg cttaatgcaa tcacagaact tccaatggat gtaagaaaga
     1021 aagttcattt taccatagca ggtcaacaac atcctaaaca ggatagtact gactataaaa
     1081 aaatgattga agatttaaag gtttcagatt gtgttctata taagccagag agaatttctg
     1141 atgaagaaat ggacagtatg ttcagaaatg cagatgccgc aatatttcca tataaagaaa
     1201 tctatggaag tggagcgctt cttatggcat acacttattg cttaccaact attgttagta
     1261 atgtacctgc ttttatggaa gaaaccgagg aaggaaagat agggttactt ttcgaaaatt
     1321 tgaattctaa gagcctagca gacacaattg taaagtatgt gaaccttagc ccagctgaga
     1381 aaagcaaaat agaggatgat atatatgagc ttgtaaaccg caagtatacc tgggcggcat
     1441 ctgcaaaact cacatacgag gcatacaaac aaattttgaa tgagtagtaa aacaattaga
     1501 aaggaataat aattaacatg cagattagta aatggaaaat catacagttt ctaatggtct
     1561 ttctaatgat tatctcatca agcatattga agcctttggg cggctggttg ggagaaacga
     1621 tgaacgttag acttgtgaca gtcattctag caatagtatg tttgttaata gcctcattac
     1681 cagcatttag aaaaaataga tatttaaatt tctgcacttt actgatttgt gttgttataa
     1741 tagcagctta catctactca gataagacaa tatgggttaa atctagggaa agtatgagtt
     1801 tatactatgt attattggcg tatccattgt tctgtacttt aattaaccaa gcgtggaatt
     1861 tggattcaat gctaaatacg atatgtggtg taacatttct ttcatacatt cttagaacat
     1921 ctatttcact tattcagaaa ttttcaggag tacttctcta tgaaaacata tatcgtgagt
     1981 gtgccccgga aaattggtat cgtggaggct ttttaagaat taatccacca tgttttacaa
     2041 ttataataat accgattgct ttgtatatga ttgagcgaca agttgtagct agaagaaaag
     2101 taaaatatta tttactgatt gctagcgcac tggcatattc tgctgttatt catggttcta
     2161 gatctgtcct tgtctatcaa attattgtac ttggttgcta tatccttttt aagaaaggtt
     2221 cttcgaaaag aaaaattgca atgtgggttt tagctgggtt gcttgtagtc atatttatta
     2281 attcgaccat gttctcaaca tttgttgaaa ctttcacaaa cagtacaggt gaatatgcag
     2341 gatctgctga atctcgattt gcttcagttt ggttttttgt tcctaaattt ttgcaatcgc
     2401 ctttgttcgg tactggtatt cttactggtg aggaatttac gtttatatta ccaggaggag
     2461 ttagaggaca cctatctgat attggatttt tctatacaat tactcaatat ggtgtaggta
     2521 tacttatatt tgatattctg tttattataa aagggttcaa aacagcatta cttgcatcaa
     2581 aagtgggtat gactggctat caatatttag catttggaat tacattaagt gttttgctaa
     2641 cagggattaa tatagactgg ttttatccga tatttactcc agctattcct gtatgcttag
     2701 cggttataga atacatctat caagaatgta gaagtgtggc taacatagaa taggaaatat
     2761 taataggagt gcatctcatg aataagaaag agattttata taacatattg aagaagtacg
     2821 aaaatttacc atatgtgttt aggaacatgt ttggtcataa tataagtaaa ctcgtatctt
     2881 ggaaattgac tgctgattgt gcaacagtag aagaaaattc tgaagtttat gcagcgtttc
     2941 aattgcgctc aaaggacatg tctgatgttc cagtgatggg tttagttaat tgttgcaaag
     3001 atgtagcaat tgtaatgcag gggccactat gtttaaagga tgatttctct tataatactc
     3061 tggcctacta taagaaatgt tatccaaatg ctttaattat tctttcgaca tggaaggacg
     3121 aagatattaa ggcattgaaa aggatagagg atcttggagt tatagttatt tgtagtgaga
     3181 aacctgaaaa gcctggacac ttaaatatta attatcaagt tggaaacact ttgcctggaa
     3241 tagtcagagc aaagcagctt ggtgcaaagt atgtttgtaa aactagaaca gatcaaagaa
     3301 tataccatcc aaatgcaatg gcgtttttct gcagtttact tgaacagtat cctgttaata
     3361 acgaagatga ttggaaatta atacaaaatc agcgattact gttactatca atgccgtatg
     3421 gagacatgtt tttcccgtat tgtttgtcag acttcctgta ttttggtgat gttgatgata
     3481 tgataaacct cttctcgatt cctagtgatg tgagagaaaa gggagctgtg tctagaggag
     3541 tctcaagaag ggagatatct gaaaataatt tagctccaga agttcagctt cttcgaagct
     3601 atatttcacg aatggggggc aatgaggagt gctctattag ggcatattgg gagtttgtaa
     3661 aaaaccatgt tattactatt aacaaaaatc aaattgattt gtactggcat aaatatgtag
     3721 gtcgttattc aaataatact atttatggta cgtattatat tgatgatagc caagatgcac
     3781 ttcactgcta taattttgat tttataaatt ggttgaattt gtacactgga aaatacgaat
     3841 acaaagcaaa atatgaaaaa tatatggact ttgtttggga agagtaatta acttttatag
     3901 taaaaagtac tttagggaag ggcatattat gaaaacagta attatggcgg gcggacgagg
     3961 aagccgaatt tcggaattgt ttccggatat tcctaagcca atgattccta tagatggcat
     4021 tccagtttta gaacgagaat tgtgttcgct tagagatcaa ggctttaatg atattatttt
     4081 gactgtttcc tatttgcatg aaaaaataga ggagcatttc ggagatggtt caaaattagg
     4141 aattaaaatc aaatatttta ttgaaaaaac tccacttggc aatgcaggtg cattgtattt
     4201 tttgttggat gaactgggtg atgaaccgtt tttacttttg aatgctgatg cagtatttga
     4261 tgttgatttc aggcagatga ttagatttca tgttgagaat aacgcagatg ttactttgtt
     4321 tacgcatcct aactcacatc cgtatgatag tggattaatt atatccgatg acaataagaa
     4381 agtgcttcaa tggttagcga aggaagatca aagacctgaa tattataaaa accgagtaaa
     4441 tgcaggtctt catgttataa atccgaaggt gttgagagaa aatccattaa tggaaattgt
     4501 aaataaatca atagttgaag gtggggggct accatacaaa attgatttag atagaatgat
     4561 tctgaaacca ttggctaaca cagggcgtat gtattgctac gattctccag agtatgttaa
     4621 agatatggga acaccggacc gatatagagc tgtaattaag gactttcaaa agggaattat
     4681 tgttggtaaa aatctatcca atccacaaaa agcaatcttt ttagatagag atggaacgat
     4741 taataaatac gttggttttt tgagaaatgc agaagaattt gagttaattg atggagtatc
     4801 ggaggcaatt aagattatta attctctagg ttttctgtgt attgttataa caaatcagcc
     4861 tgtaattgca agaggtgaag ttactgttga tgagcttaat agtattcaca ataagcttga
     4921 aacaatgcta gggcatgctg gtggattttt aaacggtatt tattactgtc cgcaccatcc
     4981 ccataaagga tatgcaggag aggttataga attaaaaatt gattgcaatt gtcgcaagcc
     5041 aaaacctgga ctgttattag aagcatcaaa ggattttaac ataaacctaa gtcaatcatt
     5101 tatggttgga gatagtgaaa gtgatgtaat tgctggaaaa aatgctggtt gtaagacagt
     5161 actgattaca gaagacatca ccttgcctgc taattatggc caagactata gtgtctgttc
     5221 attgttagaa tttgttaaaa atcatttatg cactatgcaa taattggttt agtgaaactt
     5281 gtaaaaggag taattagatg aaggtattaa ttccagcagc aaaagttgtt gaaaaagaat
     5341 tgcagagtat aggaatgtta ccagcaatta tctatccaat taataaaaaa attgtctttg
     5401 attatttgta taatcagtat aatgcaatct gcgattcatt ggatattatc tgttatgaaa
     5461 aagcggataa ggttcataga agactgaaaa actatcatga ttccagaatt catatatgtg
     5521 accttcctga attaggggat ctagggcaaa ccgtgtattt tgggttatca gatgaagatg
     5581 agcctgttct aattaacttc gcagatacaa ttgttatgga gagtatgtct gatatagaaa
     5641 tggatacatt ctattattct gaagattttg tgtcgagtac ttggacatac tttaaaatta
     5701 atgaaggaat aattactgat atccacgata aagaggaagc ttacgtatcc gataaacgtg
     5761 aaaaattatt tattggcgta tttatgtttt cttcgtcaaa acttctgaag agttgcttaa
     5821 gagaggcagt tgagagtcgg aaacaggggg gaataaactc attttatcgg gctttacagc
     5881 tatacagcga acgttgtccg ctaaaggccg taagaacaga aaagtggttt gatattggac
     5941 acatcgataa atattacaat acaaagttgg aagttaaagc acgagagttt aatcatatct
     6001 ctatagataa agatcgaggg atattgaaga aaactagcga tgacaaggat aaatttattg
     6061 gagaaataaa gtggtattta aaacttcctg ctgatattga atatgtaaga cctagaattt
     6121 ttgattattc tacatcttac gtagctccct atgttgatat ggaatattat gcatatcata
     6181 cggttcatga gttatactta tatggtgatt taaaatataa ccagtggcat gatctgttta
     6241 gccgtataaa gtttatctgt agcgatttta agcgatacac cttaaaagat gaaaagatta
     6301 gagagtcatt ggaagatatg tatttgcgaa aaaccatgca gagatttcaa aaattgtctg
     6361 aagataaaag attttcagct ttttttgaga aacaaattca aattaatggt cgtaagttta
     6421 tttctttaac cggtgtaatt gaacttctaa agaatcttat cccaagtatg ctctatgatg
     6481 taaatgaatt ttgtattata catggagatt tgtgttttgc taatatgatg gtagattcca
     6541 attgttcctt tgttaaggtt attgatccta ggggaaaatt tggaaaatat gatatttatg
     6601 gggacagcag atatgaatta gcaaaactat ttcatagttt agatggtaaa tatgattata
     6661 tcatcaagga tctatttact gtagaatatg ataccgagtg tgcagtgata gattatacaa
     6721 ttaatacgcg tgtaagagat tacgatttat ttgaattgtt taagtcggtc ttttcggacg
     6781 agattaagga cgattttgat aagattgtat tgatagaagc gttgctattt cttagtatga
     6841 ttccattaca cggtgaaagt tttgatcacc aaatagtgat gcttgctaca ggtatggaac
     6901 ttcttgcaag agtaagtaat aaagttatac tctaatataa attgtgcctt aatgaataac
     6961 ggttacaata ctgttttagc aatgtaggca ttaaggcacg attatattaa ttaatacaat
     7021 agaagggaag agaaaaatgt atagtgaata ttcttttgtg tttgatatcg atggcacttt
     7081 gtgtccgata aagaagaagg atgagcgata tgaggatttg gtgccgtatg agaatatggt
     7141 tgaaaaactg agattctata aggagaatgg tgctaaaatt acattgttca cctcacgcaa
     7201 tgttaattcc tataaaggaa atttgggaat gataaatgct aatactgcaa aagtgctctt
     7261 ggcgtggttg gataaatggg acattccgta tgatgaaatc ctgtatggta agccttggcc
     7321 ggggcataaa ggcttctatg tagatgatcg aacggttaga cctgatgagt ttttgagatg
     7381 ctctgtagat gaattaaatg aaatctgcaa cagttcaaaa aaaagattct aaataaggag
     7441 gttagttcta tggaaaaaaa gatgacagtt atcattacga tggcaggttt gggaagtcgt
     7501 tttcgaaaaa ttggttatgc ggttcctaaa tatatgatta atgccaaagg aagaacttta
     7561 tttgattggg ccatggatag tttggttgga tacaataaaa atgttgataa gtatattttt
     7621 gttgttcgtc aggaagacaa cgcttcagct tttataaagg agcattgtgc ttactttggt
     7681 attgaaaacg tagaagtgat tgaaatagac tatatgacag atggtcaagc aactacatgt
     7741 atgttggcta ttccttattg caatcaagac aatgagatta tggtttacaa tattgataca
     7801 tacgtggaat caaatgagat gaaatacgaa gatatttgtg gagatggaca tattccatgc
     7861 tttcatgctg atggcgatca ttggagtttt gcaaagctta acgatcgaaa tgaagtaata
     7921 gaagtccgcg aaaaagttcg catttctgat aattgtactc ttggtgcgta ttatttctca
     7981 tcggcaaagc tgtataaagc tttatatgaa gagtattatg cagactcctc taatatggag
     8041 aagaatgaaa aatatatagc accattatat aactttatga taaaaaaagg gttaaaggtg
     8101 actattagca tagtagatgc gaaaaaggtt catgtgcttg gtactccaga agagctcaat
     8161 gtgtttttga atcaagaata aatagtgttt aggagaaaat agcagtgacc agtaataatc
     8221 taattgtaaa aacattaagc agatataaga atactccact tcctgttaag gctgcattat
     8281 ggtttatggt atgtggtttt ttacagagag gggtttcaat gattacaacc ccaattttta
     8341 ctagagtttt gtctacagaa caatacggtt tatacagcac ttatctatcg tgggaatcct
     8401 tattgctcat gattacatcg cttagtttgt tcaaagccat gatgaatctt tatgtaaaat
     8461 atgataatca agaacatatt ctttcgacag tatccggatt gactttagta ctgactattt
     8521 tttggtttgt tattgctatt tttattaagg atatattggc agaaatttta ggattgacac
     8581 cagttctagt tgtctgtatg ttctcatatt ttatatttca ggcagaaata caatgttggt
     8641 ctttacacaa acgatatata tatgattata agactttatt agtagctacc cttgcagtta
     8701 ctgttggctc atctgtagtt ggctgtttag cggttctgtt tatatctcct accgctgagg
     8761 cgagagcctt aatgaatgtc ctagtgactg gtgttgttgg cgtggctgtg tatatatcgg
     8821 tatttagaag atgtaaggat tttaaggata atgaagtgtg gaatttcgca gtagtatttt
     8881 gtgtatcgtt gatgccacac tatttatctg aatttattct gaatggttct gataaaatta
     8941 tgataaatta cttatgtggt tcgtcagatg ttgctattta cagcgtggca tattctattg
     9001 gtgctctaat taaccttgtt acaaattctg tcaattccac ttttgcacct tatcagtatc
     9061 aaaaaatcaa gtcaggagaa tatgatttac tatcaaaaag agctaatgaa gttcttggtt
     9121 tggtagcggc tatgcttttt gcattaatgc tatttagtaa agaaattgtg ttgatatttg
     9181 gtgggcagaa atatatcgac agtgttaatt taattgtacc tatatgtatc ggtatttatt
     9241 tcaactatat gtttcagctg tttgctagag tacaggaata ctttgaaaag aaactcactg
     9301 tcgttattcc atcggttttg tgtgcaatta tgaatattgt actaaattat gtttttataa
     9361 agttatatgg gtatcaggcg gtagcataca caactgtatt ctcatatatg tttttctgcg
     9421 tcatccatta tattttttat agaaaagttt gcaaagaact attggatgga aaaaacatat
     9481 atgatgtcag aggaatactt ttgatttctg caatcacgat agctggtggc atcctaattt
     9541 caataattaa taaatttgat ttcataaaat atttaattat agcaattgct tgtgtcgctg
     9601 caattatatt tagaaaacga ttgctacttt tagtaaggag aattatgagc aaataaacat
     9661 ttgctcatag agagatagag aatgatagat attatttctg ctataatggt aaatgtatta
     9721 acagcattat atcagccgtt cttatttgcc gtattaacag cgtatctgtt tatgtactgg
     9781 tatctattta tagttgataa ctctcgagat cctaaaaact taaaagattc tgtattaatc
     9841 tggttgagat attttaaagc atctagtaaa tttcgcagac tcttttttct tgcgttttat
     9901 tttactttga tattatttaa aaccttgctt aatcgaaata tgtggatgaa cccgctttca
     9961 aacgttattg gacagtggtc attatatatt atagataatg ctacaggaga gagcagattg
    10021 acaacagaat gcgtggagaa cacgatgctg tttatccctt tttgcatgtt attgttatgg
    10081 tggcgtgaca ttaaatgtga tattatacgc accatctatg ttgggattaa gtatgtgttt
    10141 ttattctcat taagtataga atttacacaa ctgtttttta ggcttggtac atttcaacta
    10201 tcggatttgt tttataacac cctagggggc ttaattggtg ctttgctata ttggctattc
    10261 taccgattaa ataagtatat agacttaaaa tagaactgct ttgaatttta atatggttaa
    10321 tatttttctg cagacaggat tgtgtaatct catcaagaat actttacatg ccatctattt
    10381 ttgctaaaac attgttgtta tatcttcaag aggtagggaa ttttattgct ttaaatgagg
    10441 tcgagcgaat taaaaaattg gtaaaatata taacatggtg gtagttatgg taaaagtgtt
    10501 tgatataatt aagttttcgg atttcagagg atatactgct gttgcattgg ataatgagac
    10561 tcttttctcg attggtattg agtttcacat taagcaaata aatcaaggat ttagtcataa
    10621 taaatatact atgcgagggc tacattatca gagtggagag catgctcaag gaaagatagt
    10681 gatgtgccta catggtgaaa ttatgaatat cgcacttgat attcgacaag gatcttccac
    10741 ttatggatgt gtgtatgtca acacattgag tgaaagcaat ggtaaatgtg cgtatatccc
    10801 acgtggatat gctcatggct atcttactat ggaggacaat acgctagttc agtggtgcgt
    10861 agataatgat ttcaattcta atgctgccaa atgtataagt tatgaaagcg tagatattga
    10921 atggccggtc agtcggcagt gtttcgttat aagtgagaaa gacaaaaatg gggaaagatt
    10981 aagcttttga ttaaaatgag ctgtggagaa aagaaggata ctggaaaata agaagaacaa
    11041 taaccgagca aatgctcggt tatttctatg aggaatacat aaaactaaat ttagatatag
    11101 atatttattc acgaaaaact aatatt
//
LOCUS       DAFEKH010000078        10979 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.081, whole genome shotgun sequence.
ACCESSION   DAFEKH010000078
VERSION     DAFEKH010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10979
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.081"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(58..1434)
                     /locus_tag="LP386_002560"
     CDS             complement(58..1434)
                     /locus_tag="LP386_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBL1919756.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(1562..2680)
                     /locus_tag="LP386_002561"
     CDS             complement(1562..2680)
                     /locus_tag="LP386_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL1919757.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            2822..3256
                     /locus_tag="LP386_002562"
     CDS             2822..3256
                     /locus_tag="LP386_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1919758.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(3334..3867)
                     /locus_tag="LP386_002563"
     CDS             complement(3334..3867)
                     /locus_tag="LP386_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HBL1919759.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(3961..5139)
                     /gene="mutY"
                     /locus_tag="LP386_002564"
     CDS             complement(3961..5139)
                     /gene="mutY"
                     /locus_tag="LP386_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HBL1919760.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(5132..5929)
                     /gene="recX"
                     /locus_tag="LP386_002565"
     CDS             complement(5132..5929)
                     /gene="recX"
                     /locus_tag="LP386_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HBL1919761.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            6036..7418
                     /gene="rlmD"
                     /locus_tag="LP386_002566"
     CDS             6036..7418
                     /gene="rlmD"
                     /locus_tag="LP386_002566"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBL1919762.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(7592..8170)
                     /locus_tag="LP386_002567"
     CDS             complement(7592..8170)
                     /locus_tag="LP386_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HBL1919763.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            8492..8962
                     /locus_tag="LP386_002568"
     CDS             8492..8962
                     /locus_tag="LP386_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HBL1919764.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(9070..10296)
                     /locus_tag="LP386_002569"
     CDS             complement(9070..10296)
                     /locus_tag="LP386_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBL1919765.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
BASE COUNT         3277 a         2190 c         1844 g         3668 t
ORIGIN      
        1 gaaaagacgt gttgcttgtt tattcaagca acacgtcttt cataaccaag tttccaatta
       61 tcttcttggc tcgtcatctt cgaattcttt tctgaagtat cttcgttctt cttcaggttc
      121 cgcttctgtt tcttccggat catgaaaaat gacacggatt ttaaggattc gagaaccttc
      181 catttcttca gaaaccagcg taatattatc gacatcaaac gataactttt cgccttcatc
      241 cggaatcatg cctaatgctg taatcaaata accagccatc gtatctacat cactcatatg
      301 cagatcactg tcaaaagctt cattgaactc atcaatcagc atacgtcctt ggatgatata
      361 ttcgtgttca tcgatttttt cataaagatt ctcaacttca tctgattcat catcgatttc
      421 tccgacgatt tcttctaaaa ggtcttctag tgttgctaac ccaacgacgc cgccatattc
      481 atctaataaa atagccatct gattctgcgt ctttttcatt tcatataaca gatcatcaat
      541 aaagaccgtt tcaggaacga ataaaggctc ctgcatgatt ttcttgatat ctaaattatc
      601 aaagccgaat ttatgggcag cttttagtaa attctttgta tgaaggattc cgactacttt
      661 atctttgtct tcgttataaa cagggattct tgaatagttt tcggataaaa cttcattcac
      721 attttcttcc acagtgtcgt tgatatcaat cataaatgca tccgttcgtg ggaccatgac
      781 ttctcgggca actttcgtat caagagaaaa aaccccttgg agcatttcta attcttcatt
      841 attcaatacg ccttcgtttt caagcatata acgcatttca tctctggtca tttttgaatc
      901 ttcatcatca aaagtcatcg gcgtgatacg cgccaataaa cttgtggaag cagaaagcag
      961 ccagacgaag ggcttagcta ctacaccaat caagcgtatc agccctgaag tgaactttgc
     1021 gacttcttct gatttattta aagcaatacg tttagggtac aattctccaa aaacaatcga
     1081 tacataggtc aaaatagcca gcacaatgat atttgcaata ttttttgccg ctgtgccgcc
     1141 acctaatacc ggagctaacc gttccgataa agtattagct agtgaagcac cagacaaaat
     1201 gttgaccaaa gtgattccta cttggattgt cgataggaaa ttatttggat tctgcaatat
     1261 ttttaaaagc ttttgagatt tcacatctcc ttcatcagct ttttgctcga ttcgattctt
     1321 attgatcgaa acaacagcaa tttcggaagc tgctaaaaaa gcattgatca atgtcaaaac
     1381 gatcaataat aaaatctgcg ctaacagcga ctgactctca gggtcagcat tcataatcgc
     1441 attctctcct tataaaatta atttttagtt tacgatagaa aaaaacgtgg cactatagcc
     1501 acgttaaaat ggtatcacaa agcaattttc tttgcaataa aaacaagtgt actaaaacta
     1561 cctacgaggt cgtagcaatt ttcttcttgt tttcattttg cttgtcttct ttgacgattt
     1621 tgattatata ggaaatgatc gtcttgcaga ttgcgtaaaa aggaacacct aagaagatac
     1681 caagcaatcc ggcaatattt ccagctacta gaagaacgat aatgatcgtt aatggatgga
     1741 ttttcagtga tttcccaatt acattaggat aaatgatatt cccatccaac tgttggacga
     1801 ttagcacaac cacacaacaa agtaatgctt ttaccggatc attgaagact gttactagaa
     1861 atgcaggtgc tagtcctaga taaggtccta aatatggaat taggtttgtc aatcccgcaa
     1921 tgaccccaaa taagaaagca taatccacac caattaccat atatcctaaa aatgtgaagg
     1981 taccaacgaa taaacattcg attgcttgtc cgctaatgta attagccaat gttttattca
     2041 gttgccccaa taactccaca atttggtttc ttcttttttc tgggaaaaac tgttggatgt
     2101 ttggcactag tttttctccg tctttcaaca tatagaacaa gatgaatggt gctgtaatga
     2161 ttactacggt tgccgaagcg atcgttccaa cgatcgaacc taaactattg gatactccac
     2221 taaggaattg ctgaatgatt gtcccgtaag aaatgtctaa ttgctcaaaa tatttattga
     2281 tatctacttc cttgaacaaa ggcaattcgg ctacctcttt taaccagctt tctacctgtt
     2341 tgatgaaatc aggcatatta gatgccaatg aggaaatttg ctgtactaga cttgggatga
     2401 cactaagtaa aatccaaata attgctgcaa ctaaaaggag cagcacaatt gcgacagccc
     2461 atattctttt gatttttgct ttcatcaaca gcttgacaat aggattcaat aaatagtaaa
     2521 gaaagcctgc aatcagtaca ggtgcaaata acgtggaaaa aaatgtcccg atcggttcga
     2581 aaataaagtt tatttctgat gaaatcatga tcaatgcagc tatgatcaat aattcaagcg
     2641 accaaaacat tagtttagac tgtctaagtt tttcaaacaa tagatttcct cctttctttc
     2701 ttactagtat atattatatt cgttaaaaat tcttttattc tttttttatt tttgaaaact
     2761 tgccatactt tttatttgtt ttattttcca gtatactata cgaaaggaag gtggctagac
     2821 catgaaagtt gtacaaacaa aagatacaat gagcaatatt tacttagatg ctgtacggat
     2881 caggcatcaa gtttttgtag tcgaacaggg tgtgcctttg tctcgagaaa tagacaaaga
     2941 tgaagcccat tgtatccact tcgtcctgta ctcagataaa aaagaaccgc aaggaactgt
     3001 acgtcttttg cctttagaaa acggaaaaat gaaattacag cggatggcga ttctttctga
     3061 atacagacac caagggttag gaaaaatatt gattgaagaa gcagaaaact ttgctaagaa
     3121 tcaaggctat aatacgattt tattaggggc acagtccaca gctgaaactt tttacgaaaa
     3181 actaggatat acagcttacg gcgatccttt tgaagatgct ggcatgcctc atatttatat
     3241 gaaaaagact ttataaaaat ttatttcgaa aaaagcaaaa aacagcaagc ttttgagaaa
     3301 aatctctcac tggcttactg ttcttttttg tgtttactta cgcgacaatt gcttgtaacg
     3361 gttataccaa atatcaatat agccttccga gaacgggcca tctccattat tgatccagtc
     3421 aaccagaatc ttcacatttt cttttaggat gaagtcaata tcgttcgggt aattcatcat
     3481 tttgctgtgc atctcatatt catcgacatc caatagtcgt ttctcgccgt caggaaatac
     3541 cttgatatcc aagtcatagt cgatatattt caaggcctca tcgtccagca aaaaaggtga
     3601 agctagatta caataatagg aaaccccctt ttctctgatc attgctatta cattgaacca
     3661 gtatttttta tgaaaataaa caatcgctgg ttcgcgcgtt acccatcggc gtccatcaga
     3721 ttcagtgact aatgtgtgat cattcacgcc gatcatagag tgttcgcttg tttttaatac
     3781 catggtatct cgccacgttc gatgcaattt gccgtcgtgc ttgtaacttt ggatcgtcac
     3841 aaactctcct tcttttggaa ctcccatagc aacccttcct taagcagcat tttgtgcttt
     3901 gtgtttgggt gttcattaca ccgacatcat aattattata tcaataaaaa tgagctttgc
     3961 ctagaaagga ttcctattgt ttcgattttt ctctaactga tctaccagtt tcatttggac
     4021 cttaggaaaa acgaccgaat caaatgcatc aggcttcaac cacttcgaag ttttgttctc
     4081 ggtaaattct tgttctgctc cctcggttgc ccgtccgtaa aaaaggagaa catgccattt
     4141 cagatgacta aaaatatgag taacttctcc taaatgtcgt gtctgccaaa caaagagttc
     4201 ctgcttttca aatgggagat tttgctcttc ttctgctact aggtcatcaa acagatcgat
     4261 ttctggcttt gtttcccatt cttttttcaa tcgctcatac tcctcttgtg tcacttccat
     4321 cattggaaat gtccacatat tcgccagcaa tttttggcta tctctttctt caaaataata
     4381 cgctccagaa tgattttgaa gagctgcact gatataataa acgtcttttg gctttgcttt
     4441 ttttgttttt acaggaaaac tcgtttggat tcctcgtttg ttagctaaac aaaaggcttg
     4501 gatcggacaa gtctcacact ttggagaagt tggtgtacag atagctgaac ctagatccat
     4561 cattgcttgg ttgaattcac ctggatgctt ttcatcaatg attttccgca tcgcttcatc
     4621 aaagattttc ctgctagaag cttttgcgat gtctgcttca atgcaaaaca atctgctgac
     4681 tactcgcatc acgttgccgt caactgcagg ttctggaagt ccaaatgcga tacttgcaat
     4741 cgcgcctgtc gtatatggtc ctattccctt caatgagcta atttcttcag gcgtttgcgg
     4801 catttcccca tcaaattctg acatgatctg tttagcagca gcttggatgt tccgggctct
     4861 tgagtaataa ccaaggccct cccatgcttt taaaagcttt tcttctggag catttgctag
     4921 ctcttcaatt gtaggaaacc attccatgaa acgataaaaa taatcgatca ctgtgtctac
     4981 tctggtttgc tgaagcatga tctcagagat ccagatacga taaggatcac gattatagcg
     5041 ccaaggcagg tttctttttt cttgttcata ccattgaatg aactgatctt gaaattcttt
     5101 tgtttcttta tctgtccatt tttcccattc tttattcact ttcctcttcc ttttccgtaa
     5161 tgaatcgctg gatcatatcc aaatcaaatc ctttttgata taagctttgc tttactttta
     5221 gatttctttt tttaggttca aaccttaaat ttcttcgcca tagtttatct ccttgtttga
     5281 ctaaataatc atattctatt tcttgatctg cttcttgcgg aagatcagct atcgcttgtt
     5341 ggatcacttc ttgagaaaag cctttcgtca tcaatgtttg ttggattttt ctcaataatt
     5401 ctttttggct ttttccgtga ttttttccaa acgctttttc ggctgtctga tgtgcatttt
     5461 gaacttggtc ttcaaatgta tattggctga gcgcttgttc aatgatttca ggtttcaaac
     5521 ctttttgctg catctgctgc gctaatttct ttggtccttt gtcacttaag cgcatattcg
     5581 tgcgcacata actttcccca tagaccaaat catcgacaag gtccaattct tttaagcggg
     5641 ctacgatttt atttcgatct tcttgaagga tttccttttc ttttaagtat gttcggattt
     5701 ctttttccga tcgcaactga taacttaagt aattcattgc taggtgaaaa ccgaaatcag
     5761 ctccgctact cttcttgatc tcttggatag tttcttcgtc taattcccgt ccttttaata
     5821 atcgatagcg tactaataca tcttcagata cttgtaaagc ttctccttca gataaatcta
     5881 cgcgatagaa agggcctttg cctttactga ttctcgtaac ggttaacata aacatcctcc
     5941 tcgaacatat attctctatc ataccacaga aaatccccgt aatcaggtat tatatgttag
     6001 aataaaccac agaaaaaaga aaaagggaga tacttatggc agaaacaatt gtcaaaactg
     6061 gacaaacggt tcctttgaaa atcaagcgtt taggcataaa tggtgaagga atcggttatt
     6121 tcaaacggtt gatcatattt gttccatatg cactaccaaa agaagaagta ctagtgaaaa
     6181 tcacgaaagc aactcctcgc tatgcagaag gagaattaat aaaagtcaaa aaaacaagca
     6241 aagatcgcgt agtggcacca tgtcctgttt actatgaatg cggtggctgt caattacaac
     6301 acttagctta tcaagctcaa ttggatttta aaaaggatct gcttttgcaa gcattggaaa
     6361 aattcaaacc agcaggcttt cgatcttatc aacttttgcc gacgatcggg atggatgagc
     6421 cttggcatta tagaaacaaa gcacaatttc agttacgaaa aaataagcag actcaaaaaa
     6481 ttgaagctgg tttatacgaa gcaaactctc atcagttagt ccctataaca gactgcttgg
     6541 ttcaagaacc tcgaacacaa aaagtaatga atactgttgt tcaactattg aataaatttg
     6601 atgcacccat ctatgatgaa cggacaaaca gtggaatctt ccgcacaatc atggttagaa
     6661 tcggcgttaa aactggggag ttacaagttg tttttattac tcgcagtaaa aaattcccgc
     6721 aaaaaaacgc aatgatccgt gagatcaatg aacgactgcc cgaagttgtt tcaatcatgc
     6781 aaaatgtcca ggcacaaaaa acgtctctcg tgatggggga tgaaacgatc cacttatggg
     6841 gaaaagaagc cattgaagaa caaatcaatg aagtgacttt cgatctttct cctcgtgcct
     6901 tctttcaact caatcctcag cagaccgaat tgctttatgg cgaaggaatc aaagcattag
     6961 atgtccagcc taatgaaacg atcgtggatg cttattgcgg agttgggacg atcggcttaa
     7021 gtgtagcaaa acaagccaaa gaagtacggg gaatggatac cgttcctcaa gcaatcgctg
     7081 atgcaaaaaa aaatgcggaa agattaggat atcacaacac tcgatatgaa gtcgggacag
     7141 cagagcaagt tctgcctaaa tggttgaatg aaggttttca gcctgatggt atcatcgtag
     7201 atccaccacg tacgggtttg gataacgcat tgatccaatc attattgaaa taccctccaa
     7261 aaaaacttgt ttatatctcc tgtaatgttt ctacacttgc cagagatctg gttaatttaa
     7321 gtaaaaagtt caagattgaa tatttacagt ccgtcgacat gtttcctcag actgcacgtt
     7381 gtgaagttgt cgtgaagatg acgagactcg ctgactaaat gaaagaggtt gtgaaaaagt
     7441 ctgccctgta tcaagtaata agaacagcca aacaaaaata gctcttcatg ttttatgaat
     7501 actgtacttg tgaccgaaga gttaacagga ggacactatt tatttaaaaa aagggttgtg
     7561 acatagtttt tgtcacagcc ctttttgatt attattggat attcacgtct atcacttgat
     7621 aaaatgcatt tgtcgtatcg ctgatattcc atactgctaa aatcacatta tatccttttc
     7681 gatcctgcgg aagtgtgatc gtttggttga ctgtttttgg tggaacagtt gctttgtcgt
     7741 ctatttttgt gatcaattca aaatcactaa atttcaaagg ttgattagga ttccaagttg
     7801 gtttggtaat gtagtaatcc caagtacttg tccgatgttg tgctgttaaa ttccaagtaa
     7861 tatttaatgt tcctggatta accatgtttt tatgccatct gttagatgtc tgttcatcta
     7921 aaggctcaaa gccgctgact cctgcactag caatttttcc atcaatgaat gtatttttgg
     7981 tagcttcgat actttgcggt tcccattgtg ctcttccgac attttgattt aagtttcctg
     8041 ctgctgatgt tcctaggtat gcacggcttc ctggagaagt aatataacca tgcgcaaaac
     8101 ctggaatgct aaaaccgaac aaccctaaac taactaaccc aataaacaat aacgtactaa
     8161 tctttttcat gtagaaacct ccttcatttg ataaccacat tgtaaacgct ttattgtatt
     8221 aacacaaaca ttatgctttt ataattttat gttgaagtaa aaaaggtgaa aaaagtaaga
     8281 tgcagattat aacagaagta gacgagaaaa gtacaaatag aaaacatgag aatcaaatca
     8341 tatgatcttt ttcaaaaaca tcattcatat aaacaaatgt tcaacttttt aataacaaca
     8401 attatcaatt tttttcttac ttcacaaact aaatacaggt cttgctgtga gccttcatgg
     8461 taaactaata ttatagaaag gagttagtaa aatgaagatg ataaaagata ttcgtttttg
     8521 ggtttgtgtt ataggaattg tcatattagg ctttttatca gggttgctta gcggaaatcc
     8581 cggaaaatat tactattctt tgcaacttcc accatttgca ccacctagct ggatatttgg
     8641 gccgatgtgg accttactgt atatattgat gggtatttct ctttatttgt tacttaatca
     8701 caacaacaaa aaacagcgaa acaatcttgt cggtcttttt gtgattcagt tcatttttaa
     8761 ttttatatgg tctgctctat tttttaattt aagaaatatt ttcattgcag caatcgatat
     8821 tacactttta gttattttct tgtcagtgct tatgtatcag ttgtggctgc atcatcgcct
     8881 ggcaatgtgg ctcatgattc cttattattt atgggtacta ttcgcaactc tattgaatta
     8941 ttcaatttat tttttaaact aagcgctaaa aagagacgtc ctgtaattta acacatagaa
     9001 aaagtgccac ctaagttaga ttttttgtct aatttaggtg gcactcttta ttaaccaaac
     9061 tatttttttc tagtacccac ttgttgttcc atactcatta ttctggtcat aaccataacc
     9121 attttgttcc tgtccagcgt aaggatcata actttgagta tcttgacttg gtgtatagta
     9181 ctgacttgta tcttctgttt gctgataata ggtattcgga tcttggtact gatcatatgt
     9241 gttttctgaa taggaagaat aatcggtgta cccttcacta ttcgatccat caccgtttgt
     9301 cgaatcgcca tcttccgaat catcaaagaa catcattgaa gcattctcat ttttcaaatt
     9361 aggtaatgta tcgcttgttt ttatatttaa ttgtttcttc agttcatttt ggatcgaaag
     9421 aagatcattt tttcctaaaa tttgatagta gatatcattg atcatttgtc cttcgccttg
     9481 caactggtct tgtttgattg tttcaaacgc cggggtgtag ttcgtcgcta catcaagcat
     9541 gtcatcccaa tctaagtccg tcgtcacatt gttctcaact gcttttaaaa tttttctata
     9601 attgcttacg ccatctaaac ttaaaacttt attgacgatt ttcgtcacta cttcccgctg
     9661 acgacgttgt cgaccgatat cgccttctgg atcttcgtgt cgcattcgag aataggctaa
     9721 acctttttct ccattcaatg tttgttcacc tactggtaca tggacaccat ccaaagtaaa
     9781 gtcaatttta ttattcactt tgatgccacc gaccgcattg atcaaatctt ccatgccatc
     9841 caaattgatc gttacataat gatcaatagg aatatcgagc agttgctcaa ttgaatccat
     9901 ggccatttcg acaccaccaa atgcgtaggc atgatttaat ttatctaccg ttccataacc
     9961 tacgatattc gtataaatat ctcggtccaa actgatgatc gttgattttt tttgtttcgg
    10021 attaactgtt actaccatca tcgtatcaga acgtccttgt tccgttcttc ctaatccacc
    10081 ggtatctaaa cctaatagca aaaccgaaaa aggttctttg tcatcaatgc ttactctctc
    10141 agaacgtttg gaggatattc gattagagtt tttagaaatt ttgtttactg tttggctcgc
    10201 ttctcccata aatctgattc cgtatgctga taatccggca atcagcaaaa cgaatacccc
    10261 taacaaggtt aatagaactt tttgccatcg cttcataata cacctctgtt tcacattttc
    10321 taaaatattg tctcatataa ctgttcaatc agcaaattca ctttttaatc ataagaaaac
    10381 tttaaaaaac atttttgtgt aacgattatt attttttaaa atttctcaaa attcttaact
    10441 atcataccat accgtgaaaa agatcgaaag accgaataca cgcagttcgc aatcgtttta
    10501 tcttttttta tgtatttttt ccagaaaaag cgaacaacaa ggtattttcc aaataatcgt
    10561 gcagtaaaat gatcgcacat acctttccca tctttttaac agtctttgcc taccgttcag
    10621 attatcattc gatttcacga caatttcttc ctatgactgg tccttttgtt aaacccatct
    10681 tctattcgtt ttatttccag ctcactgcat ggctcttaaa atgactcgaa ctagtgattg
    10741 cattaccatc atcttttaat ggatagatat gctcctcttc aaagtaaaac gattttcttt
    10801 taaagtaata gaattgacat ggtaatgagt atgtatacta gtggtttcac aaatggtctt
    10861 ttattcaaca tccaaaaact gaaatttctt taaaatccat tactaacgaa gaaaatgttc
    10921 cttgcttgat aattagttag gacatgtcaa gtgaacaaat gcatttactt agccaaaaa
//
LOCUS       DAFEKH010000079        10717 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.082, whole genome shotgun sequence.
ACCESSION   DAFEKH010000079
VERSION     DAFEKH010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10717
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.082"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(25..162)
                     /locus_tag="LP386_002570"
     CDS             complement(25..162)
                     /locus_tag="LP386_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBL1919766.1"
                     /translation="MKRGIVMEIVKDILLVFGGSMLGVTVMCLMHASAAADRAMEKKG
                     K"
     gene            complement(159..1343)
                     /locus_tag="LP386_002571"
     CDS             complement(159..1343)
                     /locus_tag="LP386_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBL1919767.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATTCGLSRPYLNQIENGGV
                     TASTKTMRKIFDQLESFNPELPLTLLFDYVRIRFPTTDARKIIQEILHLKFDYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKPDDKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNQKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVNNTRLSDRHKKILEQQSMAIENL
                     II"
     gene            complement(1600..1854)
                     /locus_tag="LP386_002572"
     CDS             complement(1600..1854)
                     /locus_tag="LP386_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919768.1"
                     /translation="MIGKIQSDPELEEELYRLNFDIRKNGVKVPDDPYVIDEETDARM
                     ELNQVISELERIADFAKEPDIRQYLFEIKAELEIEGITAE"
     gene            complement(1879..3021)
                     /locus_tag="LP386_002573"
     CDS             complement(1879..3021)
                     /locus_tag="LP386_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HBL1919769.1"
                     /translation="MTFLDLFAGIGGFCLGMEQAGHQCIGFCEIDDFARQSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     AAILQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQNRERI
                     FLIGHSRDACTEQVFPIIGSSPTSDQNIRNLLNINPSNRGMGGQVYGSDDVAPTLTGD
                     EGIKIALPVDDGISVAGMLLGNFEQGNRVYEITGTAPTLSTKQGGTKIMLRKNETEYQ
                     EVKPGNSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKEVKTDDL"
     gene            complement(3081..4433)
                     /locus_tag="LP386_002574"
     CDS             complement(3081..4433)
                     /locus_tag="LP386_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBL1919770.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFWVALGRMSELGYS
                     MMFGEVDKKFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREISDIGGLNVNTEG
                     "
     gene            complement(4504..4848)
                     /locus_tag="LP386_002575"
     CDS             complement(4504..4848)
                     /locus_tag="LP386_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HBL1919771.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDAEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            complement(4858..5232)
                     /locus_tag="LP386_002576"
     CDS             complement(4858..5232)
                     /locus_tag="LP386_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBL1919772.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            complement(5245..5559)
                     /locus_tag="LP386_002577"
     CDS             complement(5245..5559)
                     /locus_tag="LP386_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBL1919773.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            complement(5673..8900)
                     /gene="fss3"
                     /locus_tag="LP386_002578"
     CDS             complement(5673..8900)
                     /gene="fss3"
                     /locus_tag="LP386_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HBL1919774.1"
                     /translation="MKKPRFKNWRLLATLSLLCQTIGGSLGPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSEKAKLVSVLWKEAGTDVDTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     ESKINQAIADYQKKPSFHNSTVKTVLGQSTTVTDTNGLNLSEFDEVVENIANIDYRVN
                     GNQLVITPNANSKESGELTLKKSANTGTPVAYKMAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKETGNVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGAKVTIT
                     EKSVPAPYTIDTTPITATIKSGETISVTSKNTREKGQIILNKMGVETGTDLWNDKYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASNGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGNETQGKAEFKGAEYTL
                     FTAKDGQAVKWSEAFKPELVKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDNEKNAVITRDVTAKEQVIRFGFDFFKFAGSAAGTAETGF
                     NDLTFKVSPLEGTSEITDAEDEAITAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKADYTKSEYIFTITEKGQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLGTWKDGGKELTDLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     EATKAAQEKDEKAKPVVIAETTATLANKEKTGTWKILHKLTAEQVLDKTIVLFNYVYE
                     NKKPYEAGDDPVAKDASLNNQAQTVNCTVERHVSIQTKAHLEDGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDNTTKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYGKDGNINGKHNEDLKEKTQTLTPKKVPTTPSAPEQPEIPTVP
                     SDSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            complement(8979..9641)
                     /locus_tag="LP386_002579"
     CDS             complement(8979..9641)
                     /locus_tag="LP386_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919775.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
     gene            10258..10488
                     /locus_tag="LP386_002580"
     CDS             10258..10488
                     /locus_tag="LP386_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919776.1"
                     /translation="MMEDFIRKNISDEYADFYEQSSKKDKFQMDVSILAILAFSENNQ
                     PVIAKKETVLSEGKIKTRYILEVETKFKNRSE"
     gene            10494..>10717
                     /locus_tag="LP386_002581"
     CDS             10494..>10717
                     /locus_tag="LP386_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919777.1"
                     /translation="MLFNETQLWFKFDPSNRFIKDFYKVWDSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKDVYFLFDIVTDVP"
BASE COUNT         2954 a         2365 c         1821 g         3577 t
ORIGIN      
        1 aaattttgac cgaaattcat ttcatcactt tcctttcttt tccattgctc ggtccgccgc
       61 tgcacttgca tgcatcaagc acatcacagt aacaccaagc atactgccac caaacaccaa
      121 taaaatatct ttcacaattt ccatcacgat tcctcttttc atataatcaa attttcaatt
      181 gccatacttt gttgctccaa aatctttttg tgccggtctg atagtcgagt attatttacc
      241 atatcctgaa tgtacgttgt ctgattcaac cgatccaact ccttggccat cttccacgta
      301 ggggcgactt gtcgtccaag ccagttcaac gttcgttcaa tggtataagg cttcggttca
      361 gaagttaatt gaatttcctt ctgattccgt ccaatgaagc gcccccattg ttcattcaag
      421 ggccagttag ttcgcctttt gccttccacc ttatccgcaa atcgcaagta ccggttaata
      481 atggaaaatg tggtactttc aatactgcga ccttttaaca aatcttgaat tgcatgataa
      541 gctcgatcat ttttcagtcg gatttcaaaa cgatttttcg tttcggtctg gtctaaagga
      601 atccctaact tgatatattg ctcatagtct ttttcgtaca aacagaaata gacctcactc
      661 ttaagactgc caatatacaa agtattgccc ataccatctt tatcatcagg tttcaacagt
      721 tccccggaac gatagctttt gaaggtacga aacaaggaga tacattcttc cttctgacat
      781 tttttcgtta aatcaggaat atctaacagg ccaactcgat cattgattgc caggtctaag
      841 cgtttcatca cgccaccggc ttttagacaa tcttcgaaaa agtcatacca gctacgcttt
      901 tgggcgagta aaaaagtttc aaactgccga caaccacgac cctttaattc taaaaggacg
      961 cctttatctt cttcatgtga caacatcacc acaatatctc ccataacata ttgttcttga
     1021 taggagtaaa aggcgtaatc ttcgtggagc atataatcaa atttcaaatg gagaatctct
     1081 tgaatgattt tcctcgcatc cgttgtggga aagcgaatcc ttacatagtc aaacagtaac
     1141 gttaaaggta actcgggatt gaaactttcc agttggtcaa aaattttcct catggttttt
     1201 gtcgatgcgg ttacgccacc attttctatc tgatttaagt acgggcgact aagtccacaa
     1261 gtcgtagcta atttattttg tgaaacgcca tattcattac gccggtcttt taatagccga
     1321 taatctaaat tcctttgtgc caagttctca cctccaaatt taaggtgtta actttttcaa
     1381 atcagttaac atctacacaa attgcttatt atccttgata ggacagccat tccttatcgt
     1441 tgcttgctta ttttttgtgt ttttgtaccc ccctgttaga tacggggggg tgagacatca
     1501 tggccggcta acgccgtcca taaacaggca cagcaccacg gaggatttct gcttcgcaaa
     1561 tcccccgcgg tcagtgccta tcagtggttt atttggccgt tactccgcgg taataccctc
     1621 aatttccaac tctgctttta tctcaaacaa gtattggcgg atatcaggtt ctttagcaaa
     1681 gtccgcaatt cgttccaatt cactgatgac ttgattcagc tccattcgag catccgtttc
     1741 ctcatcaatt acatacggat catcagggac tttcaccccg tttttgcgaa tatcaaaatt
     1801 gagccggtac agttcttctt ccaattccgg atctgactga atcttgccaa tcacccagta
     1861 gattccccaa tcaactcatc ataaatcatc tgtttttacc tcctttaatc ttctagcaat
     1921 atcaaaaatg accggaactg ttacagaatt tccagcctgc ttatacaact gactatctga
     1981 attgacttga gaagctcgat caaaagccca gtccggaaag ccctgaagcc gccagcactc
     2041 cctaggtgtt aactttcgaa tttgatactg atccgtgacg actgcttgtt ggtctcctgt
     2101 taataaggta tgcacacttt gttttcccag acggcctcga cgacttgtgg aattaggaaa
     2161 agccaggttc acactgttcc ctggcttcac ctcttgatat tctgtttcgt ttttccgaag
     2221 catgatcttc gttccgcctt gtttcgttga caaagtaggc gctgttccag ttatctcata
     2281 aacccgattg ccttgttcaa aatttcccag taacataccc gctacagaaa ttccatcatc
     2341 taccggcaat gcgattttga ttccttcatc accggtcaag gtaggcgcta cgtcatctga
     2401 cccatagact tgtcccccca ttcctcgatt ggaagggttg atatttaata agtttctgat
     2461 gttttgatca gatgttggag acgatccaat gataggaaat acttgttcgg tacatgcgtc
     2521 tcgagaatgt ccgataagga agatccgctc acggttttgg ggaacgtagg cctttgagtt
     2581 aagcacttgc cattccacat cataccccaa tccatccagc gttcggagga tcgtctcgaa
     2641 cgtagcccct ccttcgtgat tgagtaatcc ccggacgttc tcaaggaata aaaacttagg
     2701 ttggagaata gcggcgaacc gagcgatttc aaagaataaa gtacctcgag tatcggaaaa
     2761 tccttgccgc tttcccgcaa ttgaaaaagc ttggcacgga aatccaccgc aaaggatatc
     2821 cactggtccg agagattgaa taaactcgtc tgatacactt gtgatgtcat gcatttccac
     2881 ctccttactt gtatcatgga ttgccttata actctggcga gcaaaatcat caatttcaca
     2941 aaagccgata cactggtgac ccgcttgttc catacctaag caaaagccac caatcccagc
     3001 gaataaatct aaaaatgtca taaatcacct cgtaaaaaaa gcccaggatt cttgacactc
     3061 ctaggctaca tactattatt ttatccttcc gtattaacgt ttaatccacc aatgtcgcta
     3121 atttccctta agaaatcata tccttttggt acaagtggcg tataaaactc actaatcaca
     3181 ctccctcccg tatctacata gcctcgacct ttgatacgct tcataaagaa ttttttatca
     3241 acctcgccaa acatcatgga atatcccagt tcactcatac gacccaaagc cacccagaaa
     3301 ttaaattgat cgcgaatccc gtctcctaaa tatttcgcat ccggtctttg acaagctaga
     3361 atcagaaaga aaccagattg acgacctaac atcacgattt gtttgagctt attcaaaatc
     3421 accgcacttt ccttcgtcgt taacatttcc atataaacca cgtattcatc aaagattaaa
     3481 aagtttggtg gaagtccaag aaacgcataa ttctctcctg ttttgtagtt gggcatttct
     3541 ttcattgcct tgctacgagt catcatgcgc tcatagaaat cttccacaca agcagaaatt
     3601 tcctcctttt gggaatagac atgaggcatt accgtaccta aatcggctaa gtccgcattt
     3661 ttgggatcaa gaacaaaaag ctcggcatca gattttaata aagcctcgat gatagtgagt
     3721 aaaaagtaag tcttcccacc acctgtgccg ccagcgatta acatatgagg taaagaatca
     3781 taagcccata cttgattttt catcaatcgc aaagccccac tttctgccac tacttcgtct
     3841 atcccaattc gattggcaat tatatcatac agtaaagtgt actccacata ggagtctttg
     3901 agttcctttt ctactagttc acaatataga ccactttcta acttcttttc cagctttaaa
     3961 agctgatctt gatattttcc cagtgaaatt tgaacgcgaa tagaaagtaa accatccttc
     4021 atacggtaat agattttggg gaagtaactg attgtctctt tggttcgact actattgagg
     4081 tctttgaaaa atccttcact ctgagtttgt tttacttcgt accaatgatt ttctagaatc
     4141 atccgggcta gcttttgtcg atgccacaaa ctgcgccaat gatcctgaaa aaagtgtata
     4201 taaagcaaca tcgtgcttcc tgaaagaacg agacttccta gcaaatagat taaatctttt
     4261 atagaacgaa cgatttctat agtagaaagt gatagcttag aaatatcaaa ttgtctaagc
     4321 tcttgaaaat aaaagacgct catccaaccg atgaacagag cgagtagcca gccaagaaca
     4381 aagtgataaa ccaagtgctg atctcctgcc cgtatacgat gccctttgta catttttatg
     4441 gtttccacct ccaatcgaaa aaagcttcat aggatttcat tgatccaatt tcaagcagtt
     4501 atgctagtca tttactgcta tagggagttg tttcgtttcc actagttgct ttaaaaaaac
     4561 ttcaatggca tccggcattt ccacaccaat ttcttccaat acggtttcgg cttctcgaca
     4621 tagactttca tttacttcga taaccataaa gaaggactct tcttccccta accaattcag
     4681 tacatcaaaa tcttcttcgg catcgttacc tacttccagt aacccttgat gcataatcag
     4741 aaacattttt tcatcatagg ttaatgcttt agtgagttgt tcctccgtta gctcaccttt
     4801 tccatattga tcgagacaat ctaaaatatg ttcaacatta atttccatac gcttcaccta
     4861 tttctttcct tcattttggt ttgtagaatt tccctgatct ggttgtcgtt tcaagactaa
     4921 atcatcggcc ttaatgaacc aattgacagt agttccttct cggaaaacat aattggcgac
     4981 cgtatccatg attggattga ccaactctac ctctgcgtca taggcaaact cgcgtaaggg
     5041 tacatttgct gggatactaa cttggatcat tcgaccttgc gcagaggatt tcaaattata
     5101 agtccgttct tttacctcgt tactaaccgt tccatcctca ttttgcttcc gtacttctcg
     5161 gcgtaatgcg gaaaatcgta atttcccaaa cgttagtcct gaatctacaa caataccttc
     5221 tgttaatctc atcttctttt cctcctatgc tttcactaaa tcatcgacat acaacacgta
     5281 gtcggtaaac ccacgattct caatctcata gcctttggca accaaatggg gattcacggc
     5341 ttttagtggt tgatcttgat caaaatcctt ttcgccggct tccgcagcta ccaccacttc
     5401 aatatcatcg gctcgttgct tactggaata caaatgataa ctacgaccaa ttactgtagt
     5461 attccgccca tatccttcag ttaaaacttc gccttcgccg gcatacctta tctttccaaa
     5521 ggtttcggcc atatctggca caacaaattt caattccatc ttcttttcct cttttcattt
     5581 ttagttttgg atacaaaaat agcgcgacca ctttttttag gaggcggtcg cgcacgttgg
     5641 tttttcctat ttagttgttt catcacatca ccttagtttc ggcgattcca gaaataatac
     5701 ccagcagtcg caaagatcaa ggtaaaccca ataaacagca gaacattaga atttttctcc
     5761 cctgtttgtg ggaatgtctt tactgtagga ctagattctt gagagtcact tggaacagtt
     5821 ggtatttccg gttgttctgg tgcacttggt gttgtcggaa cttttttagg tgttaaagtt
     5881 tgagtttttt cttttagatc ctcattgtgt ttcccattga tgtttccgtc tttgccatag
     5941 ttaatttctt tgaaggtaaa acttgtacct tctggatatt tacttgtgtc cactttttcc
     6001 gcaagtacgg ttttagtgaa ttctttgtca ttcacttcat aatcaatttt gccagatttc
     6061 caaatttctt tggtcgtatt atccggaagt aatgcataca gaattgtttc aaaagcttct
     6121 tttgagccat ccagtacatc atgggtaatc gacacatcat cgaacatatc caccacatcc
     6181 ccatgagtaa aggtttgcga accatcttct aggtgggctt ttgtttggat ggaaacatgg
     6241 cgttccaccg tacaattgac agtttgggct tgattgttca agctagcatc tttcgctact
     6301 ggatcatcac ctgcttcata gggtttcttg ttttcataca catagttgaa taagacgatg
     6361 gttttatcca aaacttgttc tgcggttaat ttatgcaaaa ttttccaagt tcctgttttc
     6421 tctttattcg ccaacgttgc ggttgtttcg gcaattacca ctggtttggc tttttcatct
     6481 ttttcttggg cagcttttgt cgcttccaca tcaatggctt gcgctaccac ataccagtct
     6541 tctttgattt catgcaagtt atagctcaat ttatcaacta gctcggtaga atcaaggtct
     6601 gtcaattctt tgcctccgtc tttccaagtc ccaagagaag ttaagctatc ttcttcttca
     6661 ggtaaatcat agagcatcaa acgattcaag ctaacagaaa atgctttatt cgtcagtttc
     6721 tcgtaaggaa cggtcaccgt tttaattggt tgtttttgtc ctttttcggt aatcgtaaaa
     6781 atgtattcac tcttagtgta atccgcttta ttttctttaa aagtagaacg gatttctaat
     6841 ggcgtaattt tttgaaatcc ttctggagcc tctacttctt caagtaaata atccccataa
     6901 ggaagatttt caaacttgcc atagccatca aaacctagtt gctcgttata agctgtaatt
     6961 gcttcatctt cggcatctgt aatctcactg gttccttcca atggcgatac tttaaaggtc
     7021 agatcattga agccagtttc ggcagtccca gcagctgatc cagcaaattt aaagaaatca
     7081 aagccaaagc gaatgacttg ttcttttgcc gtaacatctc gggtaatcac ggcatttttt
     7141 tcgttatcat ccaccttttt gatggaaaca gggtactttg tttcatccaa ggtatatcct
     7201 tcaggtgctt tggtttcttg ccagtaatac tcattaatcg ctaagtgttt aacagcaact
     7261 tgattctttt catctaaagt caaagtcacc gtttcatcag aagctttcgt tcccttcact
     7321 aactctggtt taaaagcctc actccatttg accgcttgac catcttttgc agtaaagaga
     7381 gtatattcag ctcctttaaa ctcagcttta ccttgagttt cattaccggt atctttgtct
     7441 tcttttgtca aagtggtttc accagtgatt tcttggtttt gcccttttac gttactggta
     7501 acaagagcca cggtttgatt gacatagttc aattcgactt ttactggttt aaaggtattc
     7561 acaaagccat tactagcttt ggtttcggtc acataatagg ttcccaattc caacgcattg
     7621 gcaatctctt ttggtgtttc cgcatgacct ttttcatccg tggtcatttc ttggacaatt
     7681 tcaccggttg gactgtcttt gcgaatggca aacgtatttc cggctaatga gtatttgtcg
     7741 ttccaaagat cagttcctgt ttccaccccc attttattca aaatgatttg acctttttcg
     7801 cgagtatttt ttgaagtcac agaaatagtc tcaccagatt taatggttgc ggtgattggt
     7861 gtagtgtcaa tcgtataagg agctggcact gatttttcag taatggttac tttcgcgcca
     7921 tgaggaatct catccaatgt cgcaatgcct tctttatcgg tggtcacgtc ttttgcaggt
     7981 aatgtttttc caaagtctaa atggaaaacg gttcccggta caacatttcc tgtttcttta
     8041 tcgacttttt taatcttcaa agaaccctca gtttccacat caattttgat tgtgtaggta
     8101 ttgggcttat caattgcccc cgccatcaaa gtttgttgac cagccatttt ataagctacc
     8161 ggtgttcctg tattagctga cttctttagg gttaattcac cactctcttt tgaattggca
     8221 tttggagtaa tcactagttg attgccgttc acacgataat caatatttgc gatattctcg
     8281 acaacttcat caaactccga taaattcaag ccgttcgtat ctgtcacagt agtcgattga
     8341 cctaacacgg ttttcactgt ggagttatgg aagcttggtt tcttttgata atccgcaatg
     8401 gcttgattga tttttgactc aatggctgcg atatttactg cactaccatc agaacgttta
     8461 attgagtgaa gcgtgtagcc attaacttct tgccaaatca tcttctgggc cacaatatgt
     8521 gtatccacat ccgtaccagc ttccttccat aaaacggaaa ctaatttcgc tttctccgac
     8581 atatcaggca atggattttt ctcataacca ggagtgaact cattgtaaat cggcacccct
     8641 ggctcaatac agaaaatatc ttgcttcaca ccattgtaaa ctgcatagtg cggaacggta
     8701 acttctgaca tgggacgacc atcgctaaat gtaccttcga cagcatactg gtgagccaaa
     8761 tccaattcca cagttaccgt ttgtggatga gtaatttcat cagcaaaggc aatcgttggg
     8821 ccaagcgatc caccaattgt ttggcataat agactcagtg ttgcgagcaa acgccaattc
     8881 ttaaatcttg gctttttcat aaaataaatc tcctttcgtt tttgggtaat aaaaaagacg
     8941 tccaaatttt aattttgaac gtctgattta gagtgatact atttagtttt ctttgtcttg
     9001 gataggttgt ttctctgctt ataaattttg attcttcgat aatcaaatcc aatctctgcc
     9061 atcaattcct cccaattttt gttcgttctt ttcataattg tatcaactga tggtagtttt
     9121 ggggattgaa ctagttttcg aaactttgtc attgataaat catcctgtag ttttaatcgg
     9181 attatttcat tttttagttc taacagcagt tcgaaatcag taaatcgaga tccatcattt
     9241 ttttctttaa aaagtggacg tatatctcct aacatctttt taatggtact aagtgaagga
     9301 atattcttcc ctactgattt ttgttcgtac attcgttgag aggttatctt ctcgcactta
     9361 ataaaggctt ctactatttc caataattct tgttctgaca ttctagccca ttttccatac
     9421 ccagtatttt ctcgtcctat actaatcaat aaattctccc atgatccata ttttttgtta
     9481 atgaaccaca tacttggtgc agaatttgga ttttctgata gctttttctg gtattgacgg
     9541 ctagatgtaa ttccgtgttt ttcgatgaat tcattaattg ttaaaatcag ttttaactca
     9601 ctttgatttt tccaaatgat acgtccatca ttttgcttca cgataaaaac tcctaatagt
     9661 tatttagata gaagcctatc acatcaactt tttagtagaa aagtacatgt tttgtctttt
     9721 ttgctaatag ctgacccttt gagaaacttg ggttcaaaag ttgctaaatt cggtaaatgt
     9781 tttggtattt ttcgtattat atttgtcgtc aagctgacta ctaaattttg ccctattttg
     9841 acgacactga tagtcaatgt cggacaatct aggacaattt ttaagggaat atgattgaaa
     9901 aatggtccaa aacagccaaa aatggcttaa aactgtgata gagaaaaaag aaaaagccct
     9961 tgatatacaa ggacttttca caaatttcag atttccaagg aagttttccg tgtttatctt
    10021 ctgatttctt tgatacgagc agcttttccg tgtaatgcac gtaaacaaaa ccactatatt
    10081 ctattatgta tctaataccc tcaaaacagc tataaatcaa caataccgac atataataaa
    10141 cactatgttc aatctgagat atatcaaagg taaacgtatt tttgccccct ttttgcccct
    10201 caaatatcgc tttacaacga gaacgtaagt tcgtataatc gttttgaggt gatttttatg
    10261 atggaagact ttattagaaa aaatatcagt gatgaatatg cagactttta tgagcaaagc
    10321 agcaaaaaag ataaattcca gatggatgtt tcaatcttag ctatattagc tttttccgaa
    10381 aataaccaac ctgtaattgc gaaaaaagaa acagtattat ctgaaggcaa aataaaaact
    10441 cgatatatat tagaggtaga aactaagttt aaaaatagat cggagtaatg gctatgcttt
    10501 ttaatgagac gcaattatgg tttaaatttg atccttcgaa tagatttatc aaagattttt
    10561 ataaagtatg ggattcagaa gttttctttt tagcaatcga agatagttta ttaatcaatc
    10621 tctactattc taataagaac tatttcaaaa ttcctgctgc gaaaactaga atgaagaagg
    10681 atgtatattt tttgtttgat atcgtgactg acgtgcc
//
LOCUS       DAFEKH010000080        10198 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.083, whole genome shotgun sequence.
ACCESSION   DAFEKH010000080
VERSION     DAFEKH010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10198)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10198)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10198
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.083"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..948
                     /locus_tag="LP386_002582"
     CDS             <1..948
                     /locus_tag="LP386_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HBL1919778.1"
                     /translation="AFLWKDPQTNETVGASYQGTFIDYERFGERGTYKHIDKNSTANH
                     GFNLKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSE
                     LRKKQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEY
                     KVIYEEVAKEEKITPEAIMAIHKTENNLQLTNQLVSAHKVNASFGQQLSVNDSIEAIN
                     LKDICREVAKELKACERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEF
                     VPEVKKDWNDQLKHEIYQQEIRKQKRAMLFQQGRQQERE"
     gene            959..3163
                     /locus_tag="LP386_002583"
     CDS             959..3163
                     /locus_tag="LP386_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HBL1919779.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFSGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQAGADHGKIFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGTIHQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKTVGKVPVDLGWKKLFGK
                     ESDRKEKEEEPLLPKVTKGEAVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGEQKGTQATFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEATRHLGVCPKCREQEVLLYQNVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNGRTSQSVRGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNYKKRTRRTTK"
     gene            3179..3328
                     /locus_tag="LP386_002584"
     CDS             3179..3328
                     /locus_tag="LP386_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919780.1"
                     /translation="MRNTTHKQQEIENQKAKIRLEQEKLRANKRRLQQLKNQQRIQKE
                     IELDR"
     gene            3404..3997
                     /locus_tag="LP386_002585"
     CDS             3404..3997
                     /locus_tag="LP386_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HBL1919781.1"
                     /translation="MQDKLKELLAIRDGNLSMKEARKFGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEFEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            4010..4909
                     /locus_tag="LP386_002586"
     CDS             4010..4909
                     /locus_tag="LP386_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HBL1919782.1"
                     /translation="MTPTQFAAKTRNLAKSTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTEQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIRGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            4912..5385
                     /gene="ssb"
                     /locus_tag="LP386_002587"
     CDS             4912..5385
                     /gene="ssb"
                     /locus_tag="LP386_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBL1919783.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFANQNGNR
                     EADFINCVIWRKPAETMATLAKKGGLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSTTSPSPTTFEQRDTNNGLDASQNPFGGQSIDISDDDLPF"
     gene            5751..6011
                     /locus_tag="LP386_002588"
     CDS             5751..6011
                     /locus_tag="LP386_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919784.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDQFTRLMGI"
     gene            6456..6662
                     /locus_tag="LP386_002589"
     CDS             6456..6662
                     /locus_tag="LP386_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HBL1919785.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            6662..6913
                     /locus_tag="LP386_002590"
     CDS             6662..6913
                     /locus_tag="LP386_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919786.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTTETPLV
                     EDAPTMLFEDLVKIAGYELHYQENLETYENEYWLTELEN"
     gene            6929..7345
                     /locus_tag="LP386_002591"
     CDS             6929..7345
                     /locus_tag="LP386_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919787.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFIETKKAKTVSSEWLDYFENINKYGACYIMK"
     gene            7327..7599
                     /locus_tag="LP386_002592"
     CDS             7327..7599
                     /locus_tag="LP386_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919788.1"
                     /translation="MLHHEVIRRIQKDFSCMEEMKYFVQNVEEQLYLESETSQTKVTV
                     SHNRLDVYKRRPESLKKGAELLRLETEKYVMNVYLEKSELVENFMD"
     gene            7766..8167
                     /gene="tnpA"
                     /locus_tag="LP386_002593"
     CDS             7766..8167
                     /gene="tnpA"
                     /locus_tag="LP386_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_045009167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBL1919789.1"
                     /translation="MSEIHYGRGYVYSIQYHLVWCVKYRHDVLYGQVDIDVKQFLKQI
                     ADDNNIKIIEIESDKDHIHLLIECTPQHYIPSIVKVFKGASARLLFKKHPELKQLLWG
                     GHLWNPSYFVATVSENTEEQIRKYIQNQKKK"
     gene            8179..9324
                     /locus_tag="LP386_002594"
     CDS             8179..9324
                     /locus_tag="LP386_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1919790.1"
                     /translation="MLQHRAYKFRIYPNQEQEILMTKTIGCSRFVYNYFLNLWNHEYT
                     TTGKGLSYNSCSAMLPQMKRNAETIWLKEVDSIAIQSSLKNLSDAFSRFFKKQNKRPQ
                     FKSKKHPIQSYTTKNVNNSIEIRNNFVKLPKLGFVKFAKSQEPKGRILNATIRKNSSG
                     KFFVSILCEEEIVEFPKSNSAIGIDLGITDFAILSDGQKIDNNKFTSKMAKKLKREQR
                     KLSKRALLAKKKGVNLFEAKNYQKQKRKVARLHEKVMNQRNDFLNKLSTEIIKNHDII
                     CIEDLNTKGMLRNHKLAKSISDVSWSSFVTKLQYKANWYGRKIIKVDKWFPSSQICSN
                     CGHKDGKKSLEIREWTCPVCHAHHDRDINASINILTEGLRLHVMGLA"
     gene            9562..9825
                     /locus_tag="LP386_002595"
     CDS             9562..9825
                     /locus_tag="LP386_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HBL1919791.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            9819..10169
                     /locus_tag="LP386_002596"
     CDS             9819..10169
                     /locus_tag="LP386_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBL1919792.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
BASE COUNT         3809 a         1664 c         2028 g         2697 t
ORIGIN      
        1 gcctttttat ggaaagatcc acagacaaat gagacagtag gggcgagtta tcaaggaacg
       61 ttcattgatt atgaacgttt tggtgagaga ggcacatata agcatataga taaaaattcg
      121 acagcgaatc atggctttaa cctaaagatc ggtgacccta agcagttaaa attttttgag
      181 agtagtattg atttacttag ctatgctgca ctaaatcgtg atcagttaaa cgatacgtgg
      241 ttagtttcga tggaagggtt aaaacaccat gtgatcagtc attattttgg tgaggcagta
      301 tctgaattga gaaagaaaca agcctttcct caatccatcg agatttgtgt ggataatgac
      361 cgtgcaggac atattttcta cgaaaaagaa caattaatgg gcgcagttga tccatttacg
      421 aatcagaaag tacgttgtga acgaggaatc gctaatgatt ggcaagtgcc aaaagaatac
      481 aaagtcattt atgaagaagt cgcaaaagaa gaaaagatca caccagaagc tattatggcc
      541 atacacaaga cagaaaacaa tctgcaatta acgaaccaat tggtttccgc tcacaaagta
      601 aatgcgtctt ttggtcagca gctttctgtt aacgattcaa tagaagctat taatttgaaa
      661 gatatttgta gagaagtcgc aaaagaatta aaagcttgtg aacgcgtgga tggtacgtac
      721 gattttgatc gtttttatca agaaaaaggg gatattaatg ctcagattct tttctcttat
      781 aaagcagaac aatactacaa aggctataaa aatcatgaac atgaatttgt acctgaagta
      841 aaaaaggatt ggaatgatca attgaagcat gaaatctacc aacaagagat cagaaagcaa
      901 aaacgtgcca tgttgtttca acaaggtaga cagcaagaaa gggagtgaaa tcgtcatgat
      961 gaaaaccgtt attttagcag aaaaaccgtc acaagcgaag gcttatgccg atagcttttc
     1021 taaagctacc cgaaaagatg ggtattttga gatccaagat cgattgtttt caggagaaac
     1081 tgtgatcacg tatggttttg gtcatttagt cgagttagat tcgcccgata tgtacgatga
     1141 aaattggaaa caatggtcat tagagcattt gcctattttc cctacacatt atcactatca
     1201 tgttcctaaa gataagaaaa agcaattcaa ggtggtgaaa cagcaacttc aatcggccga
     1261 caccattatt attgcgacag atagcgatcg tgaaggggaa ctgatagctt ggacgatcat
     1321 tcaacaagca ggcgccgatc atggaaagat atttaaaaga ctttggatca actccttaga
     1381 aaaagaagcc atttatcagg gattccagca gttacgagat gcagaagaga cctacccaaa
     1441 atttgaagaa gcacaagcac gccagatcgc cgattggttg atcggcatga acggtagccc
     1501 gctgtatagt ttactcttgc agcaaaaagg cataccagga agtttttcct taggcagagt
     1561 ccaaacccca acgctttaca tgatttatca attacaggaa aagattagaa acttccaaaa
     1621 agaaccatat tttgaaggaa aagcccaagt aatcgctcaa aatggcgcat ttgatgcgaa
     1681 gcttgatccg aatgaaaccc aagcgacgca agaagcattt gaagattatt taaaagaaaa
     1741 gggggttcaa ttgggaaaac agccaggtac gatccaccaa gttgaaaccg agaaaaaaag
     1801 tgcggcaagt ccacgtcttt tttctctatc cagccttcaa tctaaaatga atcagctcat
     1861 gaaagctagt gccaaagata ctttggaagc catgcaaggg ttgtatgaag ggaaatatct
     1921 aagctaccca cgaacagata ccccttatat tacagaaggg gagtatgcgt atctgttgga
     1981 tcacttagac gaatacaaac actttttaaa ggccgaagcc attcctactc ctattcatac
     2041 accgaatagt cgatatgtga ataataagaa agtccaggaa cattacgcga tcattcctac
     2101 aaagacggtc atgacggcag cggcttttga acaattaagt ccactgcagc aggctattta
     2161 tgaacaagtg ttaaaaacaa cggtggccat gtttgcggaa aagtatacct atgaagaaac
     2221 aacgatcttg acgcaagttc agcagcttca gctaaagaca gtcggaaaag taccagtaga
     2281 tctaggttgg aaaaagctgt ttggcaaaga gagcgacaga aaagaaaagg aagaagaacc
     2341 gctacttcct aaagtgacaa aaggagaagc ggtgacggta gatctacaag tccttgaaaa
     2401 agaaacgaag ccaccacaac cttataccga aggtacgttg atcacagcga tgaaaacagc
     2461 tggaaaaacc gtggatagcg aagaagcaca atccatattg aaagaagtag aaggaatcgg
     2521 tacagaagca acacgagcaa atattattga aactttgaaa caaaaggaat atatcaaggt
     2581 agaaaaaaat aagcttgtgg tgacaaataa agggatttta ctttgccaag ccgtggaaaa
     2641 agagccgctg ctaacaagtg ccgaaatgac cgccaaatgg gaaagttact tattaaagat
     2701 tggtgagcag aaaggaacac aagctacttt cttagctaat atccaaaaat ttgtctctca
     2761 cttgttggaa gtcgtaccgg gacaaatcca gtcaacagat tttggatcaa cgttacaaga
     2821 ggtgaaagca gccagtgaaa aacaggaagc aacgcgtcat ttaggtgttt gtccaaaatg
     2881 tcgggaacaa gaagtcttgc tttatcaaaa tgtggcggca tgtacgtctg aagcctgtga
     2941 ttttaaatta tggacaacga ttgccaaaaa gaaactcaca gccacacaac tgaaagagat
     3001 cattcaaaac ggccgaacaa gccaatcagt cagaggacta aaaggtcaga aaggttcgtt
     3061 tgaagcaacg atcgttttaa aagaagactt tacaacaggc tttgaatttt ctgaaaagaa
     3121 aaaaacgaac tataagaaaa gaacacgccg cactacaaaa taatgaaggg gttatcctat
     3181 gcgaaataca acacacaaac aacaagaaat cgaaaatcaa aaagcaaaaa ttcgtttaga
     3241 acaagagaaa ttacgtgcaa ataaaagaag actgcaacaa ttaaagaacc agcagcgcat
     3301 tcaaaaagaa atcgaattag atcgatagac gttaatcttg ttacaaataa actactatga
     3361 tatatttgat gtagtgtatt tgtaacgaag ggaggggaag taaatgcaag ataaactgaa
     3421 agaattgttg gctattcgcg atggaaattt atctatgaag gaagccagga aatttggaat
     3481 cgcagcaacc actgtacaaa gattggtgaa tcaaggaaaa ttgatcaaag ttgatcgtgg
     3541 ttattatgta gaggatggtc atggaataga tgatttattt tggcttcagc aacgattttc
     3601 caggggaatc ttctctcatg aaacgacttt agatatttac cagctttcta cgaatatgcc
     3661 gaaattcatt cacttaactt ttccccatgg ctataacgtt gatcgttcaa ttacaaaaga
     3721 gcagcagtta caatttcatt tcgtgaagaa agaagtttat gaactaggaa aagtagaggg
     3781 aacttccttt caaggaaatc ctattactat gtatgataaa gagcgtacac tttgtgatat
     3841 ttggaatccg agatatgaat ttgaatatga aatgaaatta gaagcattaa aagagtacat
     3901 ggaagaccca ttgagagatc caagtaaatt aagagattac atgacaaaac tacatgtaga
     3961 aaaagaaatg aaataccaca tgcaaagctt atattgatgg aggaaaaaga tgacaccgac
     4021 acaatttgca gcaaaaacaa gaaatttagc aaagagtaca ggattaaatg cacagttagt
     4081 gcaacggcat tttatgatgg atcgtctaat tgaacaaatt tctgaatcaa agtacaaaaa
     4141 tgacttcatt ttgaaaggcg gctttttatt aggatcaaaa tatggaatcg atagaaggac
     4201 aacaattgat atcgatacga catttagaaa tagcaaatta actgaagaaa aattgaagag
     4261 catttttaat gatttaacta gaaaacccac aaaagaaggc attgttttct ctattcaagg
     4321 aatgaaggaa acaagagaag ccgattttta tcctggattt caaattaaat tggtggctaa
     4381 tttagagaaa gtacgtgtac cgtttaaaat ggacgtgaca acaggagatt ctatttatcc
     4441 tgaagtagat acacactatc accaattaat gtttgaagat aaaaaagtgg agattccagc
     4501 ttatccaaca gaacaaatta ttgcagaaaa gctaagtgct acgttcagct ttggcacaga
     4561 taattcgaga gcaaaagatt actacgactt atttaccatt ccgaaactag aaaatatcga
     4621 tacgaaagag ttatacaaaa gtgttcgaaa tacatttaca aaacgtgggg atacaaaacc
     4681 gttgtccttt tattatgaaa gagaaatgga taagatcaga ggaaatgact atttggaaaa
     4741 gcagtgggaa aaatatcgct cagttaacac gtttgcgaat tccatttcat ttacagatac
     4801 agtcaacgaa attgatcacc taatgaaaag tgtgatcaaa attgaaaatc aagaaagaaa
     4861 acggcagttt aaaagatcac aacaaatgaa tcaagaaatg gagagataaa gatgattaat
     4921 aatgtgacat tagtaggacg cttaaccaaa gatcccgatt tacgttatac tgcaagtggc
     4981 acagcagtag cgacttttac cctagccgtc aaccgaaatt tcgcgaatca aaacggcaat
     5041 cgagaagccg attttattaa ctgcgtgatt tggcgcaaac cagcagaaac aatggcgaca
     5101 ttagctaaaa aaggcggctt gatcggtgtt gtcggacgga ttcaaacacg aacttatgac
     5161 aaccagcaag gacaacgtgt gtatgtgact gaagttgtag cagataactt tcaactatta
     5221 gaaagtaaag cagcgacaga gagccgtgcg cacgctgatc aatcaaccac cagtccaagc
     5281 cccactacct ttgaacaacg ggatacaaac aatggattgg acgcttcaca aaatccattt
     5341 ggtggacaat caatcgatat tagcgatgat gatctaccat tctaagtagc attttctatt
     5401 ggttgcattt gctacggttt atgttataat ttagtcaaca aaaagaattt tcaatctata
     5461 accaaaaacc actagctggc gggctagtgg ttttctttta cgtttctatt ataagaatta
     5521 acgggtaggc ttactgtctt tcttggcaaa tttacaatca agccatttgc agatatagtg
     5581 cgcggctact tctgccatga ttgcaaaaac aaaatcaaaa agaattttca aacctataac
     5641 ctcctcccct tgccagatta ggccggggta gcagacagca agactattat agcataattg
     5701 aaatattcaa atgattggat ttttgctata attttagcga ggtgattgtg atgaacaaat
     5761 atgttggttt gcttgataaa atccgagtaa taaaaacgca accgttattg gttcgcttta
     5821 ctttacaaac gattcatgaa tcgattaatt gtgtagttgc agatattgaa attatcgata
     5881 aattgctaat tatggatgat ggaaaataca atattgccgt cacaggtcac ttcaataaac
     5941 gaaaccagct agttattgct agcatgtatg ttagaaatcc cgatcagttt acgcgattga
     6001 tgggcatata aaaaaagaag agttgcaatc ctaatgtagg actgcagctc tttttgtttt
     6061 acatagaaac aagaaaaatg aaaaggcctt tttaggaagg cgcgagcgcc ttctcaattg
     6121 aaaaacctct ctcactccaa ccgccaccgc cgttcgagaa gaaaggaagt gaacgttgca
     6181 cgttcactaa gataaagggt cttgcaaagc aagacaaaat agaaaaaact tcctctcacc
     6241 aaaaggttcg ttcctgttcg ttatctcttt attgatttgc cagaccggca acaagttgcc
     6301 ttttatcacc aaaaagcgac aaggacaagg gtaaatggca cgctgcgcgc ccttgtcctt
     6361 gtcgcttttc gttgattcat tctggccaac aaatcaataa agaaagaact aacgaaagga
     6421 agtaaaacct ttcctaagag gaggcagaat caatcatgcg aaagaaattt gattattggg
     6481 gtgttccctt cagcgaatta ttcccaaact atcatgcacc acatactgtc gaatgcgatt
     6541 gtggagaaag agcgaaatgt atcaaaagct atcgtttgta tcaatgtcca acatgcggga
     6601 aaaaatatac cttgtcttat ggcgattata ttttgattga tgagaaagga aagaaacgtt
     6661 gatgaaaaca caacacaaat tattgactgt aaaagaagtc gttcaaattt tggtggacaa
     6721 agaagtcatt tctgaaaaag tagcagaagc tttacttatt ccgcggtact ggacgacaga
     6781 aaccccttta gtagaggatg caccgactat gctatttgaa gacctagtga agattgcagg
     6841 atatgaactg cattatcaag aaaacttgga aacttatgaa aacgaatatt ggttaaccga
     6901 attagagaac taaaaaggag aaaaaaatat ggctcaaaat tactatgacg aatttgtcaa
     6961 attacctttg gataaaatgg cacaaaaaat ggaggatatg acattcctat acaatgagac
     7021 acgtgttcca aaaaaacatt ataaggaaag attgtcggta gctgtggaag aaatgattga
     7081 atcaggtgtc gaaatgaatc tcattgcgac gtattatcga acactggaag aactgaaaaa
     7141 gcaaaatgca aaatggtttt tccaagcctt actatgcttg gaagtaggcg tcaaaccaag
     7201 cacaatcaaa ccttctgaat accaagcttt agaactaacg tatgcgaaat ttatcgaaac
     7261 gaaaaaagct aagactgttt caagtgaatg gttagattat tttgaaaata tcaataagta
     7321 tggcgcatgt tacatcatga agtaatcaga cggattcaaa aagactttag ttgtatggaa
     7381 gaaatgaagt actttgttca aaatgttgaa gaacagttat atttggaaag cgaaacgagt
     7441 caaacaaagg tcacagtcag ccataatcgt ttagatgtgt ataaacgtcg tcctgaatca
     7501 ttaaaaaaag gagcggagct tctacgacta gaaacagaaa aatacgtcat gaatgtttac
     7561 ctagaaaaaa gtgagttggt cgaaaatttt atggactagc cgagaacacc cgtgatttta
     7621 atcatgggat gaatcggatt cagttgtgac ctagctttag ctaggttaaa caactgacaa
     7681 atataaacta aataatagtg aaatgtcttg caataattga ttttgtagaa atacatatat
     7741 taaaataatt gcgaggtgtt tttgtatgtc agaaattcat tatggacggg gttatgtcta
     7801 ttctattcaa tatcatcttg tttggtgtgt aaaatatcga catgatgttt tgtatggtca
     7861 ggtagatatt gatgtcaaac agtttttgaa acaaattgct gatgataata atataaaaat
     7921 tatagaaata gaatcagata aagaccatat tcatttactc attgaatgca ccccacaaca
     7981 ctatattcct agtattgtta aagtatttaa aggcgcatcc gctagactgc tgtttaaaaa
     8041 acatcctgaa cttaaacaac tcctttgggg tggacatctt tggaatccaa gctactttgt
     8101 agctactgtt agcgaaaata cagaagaaca aattagaaaa tatatacaaa atcagaaaaa
     8161 gaaatgaggt gaatccgtat gctacaacat agggcttata aatttagaat ctatcctaat
     8221 caagaacaag aaatattaat gactaaaact attggctgtt caagatttgt ctataattat
     8281 tttttgaatt tgtggaatca tgaatatacg actactggaa aaggattatc ttataattct
     8341 tgttctgcca tgcttccaca aatgaaaaga aatgcagaga caatttggtt aaaagaagtt
     8401 gacagtattg cgattcaatc ctcattgaaa aatctttctg atgctttttc tcgcttcttt
     8461 aaaaagcaaa ataaacgacc acaatttaaa agtaaaaaac atcctataca aagttataca
     8521 actaaaaatg tgaataatag tatcgaaatt agaaacaatt tcgtaaaact acctaagtta
     8581 ggatttgtta aatttgcgaa aagtcaagag cccaaagggc gaatcttaaa tgctacgatt
     8641 cgaaaaaatt cgagtggtaa attttttgtt tccatcctgt gtgaagaaga aatagttgag
     8701 tttcctaaat ctaattccgc tattggaatc gaccttggta taactgattt tgcaatcctt
     8761 tctgatggtc aaaagattga taacaataaa ttcacgtcaa aaatggcaaa aaaactcaaa
     8821 cgtgaacaac gtaagttgtc aaaacgtgca ttactagcta aaaagaaagg cgtcaatctc
     8881 tttgaagcta aaaattatca aaaacaaaaa cgaaaagtag cacgactaca tgaaaaagta
     8941 atgaatcaac gcaatgactt tttaaacaag ttgagcacag agattatcaa aaaccacgat
     9001 attatctgta tagaagactt aaatacaaaa ggtatgttgc gtaatcataa actagcaaaa
     9061 agcatttctg atgtgtcttg gtctagtttt gtgactaagt tacaatacaa agctaactgg
     9121 tacggtcgga aaatcatcaa agtagataaa tggtttccat ctagtcaaat ctgttcaaat
     9181 tgtggacaca aagacggcaa gaaatctcta gaaattcgag aatggacttg tcctgtttgt
     9241 catgctcatc atgaccgaga tatcaatgct agtatcaata ttttgaccga aggtctaaga
     9301 ttacatgtca tgggattagc ttagatccaa tcatcaaaaa ccgtaggaac tacggggata
     9361 gcttggtaaa taagagaaac cgctgtgagt aaagaaatac gcttgcaagt atgctctatt
     9421 cccaagaatc tcgtgacttt agtcatgaga ggttcaagga ttcatggaat gttaatctaa
     9481 tttaatagaa aaggataatt aagtatatac gttttttctt atgtatgtta tactatgtat
     9541 atacagaaag aggtgtctac tatggaaatg ttacctataa aaaaatgggg aaatagtaat
     9601 ggccttagat tgccaaagta tattatggaa tatcttggaa ttcatacaga agacaaagtg
     9661 aagataatac aagaagaagt aaacggtcag aagcggctaa ttatcgaagc ggctaatata
     9721 gaaaatgaat taacaattga acagttattt gaaaattaca ctgatgaaag aaatcatgtg
     9781 acgattcaaa atttaggtga agcagtaggt aatgaaaaat ggtgagaaaa cctagacaag
     9841 gcgatattct attattgaat acagcacctc gatctggaca cgaacagaca ggtaaaagac
     9901 cttatattgt tttaagtcat gatattattg cggattatag taacgttgtt acagttgctc
     9961 caatttctag tacaactaga aactatccgc tatatgtaaa tataaactca gaatatgaaa
    10021 tgaagacaac aggaaaagta ttattagatc aactaacgac aattgattat gaagccagag
    10081 agtgtatttt tttggaaaaa gcgcatgata gtttagttga ggagttattg atgaaagtta
    10141 gaacagtttt tcaaaaagta agcaaataaa atagaaacag cagcatgatc aactattc
//
LOCUS       DAFEKH010000081         9633 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.084, whole genome shotgun sequence.
ACCESSION   DAFEKH010000081
VERSION     DAFEKH010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9633
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.084"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..957
                     /locus_tag="LP386_002597"
     CDS             <1..957
                     /locus_tag="LP386_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HBL1919793.1"
                     /translation="AFLWKDPQTGETVGASYQGTIVDFNRFGKRGTYKHIDKNPTPNH
                     GFNLKIGDPKHLKFFESSIDLLSYAALNREKLQDAWLVSMDGLKHHVISHYVEESISE
                     LRRKQTFPQSIEICVDNDRAGHIFYEKEQMKGIVDPFTNKKIRCERGIPNDWQVPKEY
                     KATYEAVAKEMSVEPEAIMAIHKTETNLQLTNQLVSAHDVQSTFGKMLAKGEPVETID
                     LKEACTTVAKELKVCERADGTYNFDRFYSRKANIKDVNAGILLSYKAEQYYKGYKKHE
                     HEFVPEVKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            968..2977
                     /gene="topB"
                     /locus_tag="LP386_002598"
     CDS             968..2977
                     /gene="topB"
                     /locus_tag="LP386_002598"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBL1919794.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFTGETVIT
                     YGFGHLVELDSPDMYDEKWKQWALEHLPIFPNQYHYHVPKDKKKQFSVVKRQLQSADT
                     IVIATDSDREGELIAWSIIQQAGANQGKTFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEVQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEAYLKEKGVQLGKQPGTILQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIEKVPLDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKRSEGFI"
     gene            3093..3242
                     /locus_tag="LP386_002599"
     CDS             3093..3242
                     /locus_tag="LP386_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919795.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            3323..3919
                     /locus_tag="LP386_002600"
     CDS             3323..3919
                     /locus_tag="LP386_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HBL1919796.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYTKAEWYELGKIEIKSRYGNPIIAYDPEKTLCDIWNPWYNVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTMRSYIMALN"
     gene            3932..4831
                     /locus_tag="LP386_002601"
     CDS             3932..4831
                     /locus_tag="LP386_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HBL1919797.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGSKYGIENRTTKDIDTTLREMKVTKETLTTVLNDIFSTPTKEGIQFEI
                     QGMKETREADYYPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFEDRTI
                     PLESYPTEQIIAEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTR
                     RGKTDPLKIYYEKDMDVLKNSHELKDTWKKYQKSNPYAASITYDETMDSISNLMEKVI
                     HVEEKERKLAYQRHQQMNREMER"
     gene            4834..4965
                     /gene="ssb"
                     /locus_tag="LP386_002602"
     CDS             4834..4965
                     /gene="ssb"
                     /locus_tag="LP386_002602"
                     /inference="COORDINATES: protein motif:HMM:TIGR00621.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBL1919798.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGN"
     gene            4987..5319
                     /gene="ssb"
                     /locus_tag="LP386_002603"
     CDS             4987..5319
                     /gene="ssb"
                     /locus_tag="LP386_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBL1919799.1"
                     /translation="MIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEV
                     VADNFQLLESKAATESRAHADQSSTSPSTATFEQRNTATPNNNGLNASQNPFGGQSID
                     ISDDDLPF"
     gene            5364..5597
                     /locus_tag="LP386_002604"
     CDS             5364..5597
                     /locus_tag="LP386_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919800.1"
                     /translation="MDLLIPVIAFIDGISLGVTENPLVNRIAKGSLFLVFVYLVCSYL
                     LKRAGKDNSFWRLTKVTVAATAVILTAILPLYM"
     gene            complement(5756..5878)
                     /locus_tag="LP386_002605"
     CDS             complement(5756..5878)
                     /locus_tag="LP386_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HBL1919801.1"
                     /translation="MKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK"
     gene            6068..6292
                     /locus_tag="LP386_002606"
     CDS             6068..6292
                     /locus_tag="LP386_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919802.1"
                     /translation="MIKTQPLLVRFTLRTSHEPINCVVANIEIADKLLILEEGKYTIS
                     VTGHFNKRKQLVIESMQIRNPDHFTRSMSI"
     gene            6735..6941
                     /locus_tag="LP386_002607"
     CDS             6735..6941
                     /locus_tag="LP386_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HBL1919803.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            6941..7192
                     /locus_tag="LP386_002608"
     CDS             6941..7192
                     /locus_tag="LP386_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919804.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEVLLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENLETYENEYWLTKLEN"
     gene            7208..7363
                     /locus_tag="LP386_002609"
     CDS             7208..7363
                     /locus_tag="LP386_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919805.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKEKLSV
                     AVEEMIE"
     gene            7373..7645
                     /locus_tag="LP386_002610"
     CDS             7373..7645
                     /locus_tag="LP386_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919806.1"
                     /translation="MNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQ
                     ALELTYAKFIETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            8090..8269
                     /locus_tag="LP386_002611"
     CDS             8090..8269
                     /locus_tag="LP386_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919807.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDVPALKK"
     gene            8328..8684
                     /locus_tag="LP386_002612"
     CDS             8328..8684
                     /locus_tag="LP386_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919808.1"
                     /translation="MLKTKKNSYKLKLSILSIICLLGMIISGHLYRVAYTQFIEYKVH
                     SLGLAGDRYVEYVHYSLKCSSYILLWLIFSLFELLNLIAISSYHLDKLNTKSSRYNEV
                     FKENVKLESDLNKLKK"
BASE COUNT         3462 a         1602 c         1979 g         2590 t
ORIGIN      
        1 gcttttttat ggaaagatcc acagacagga gagacagtag gggcaagtta tcaaggaacg
       61 atcgtcgatt ttaatcgttt cggtaaacgg ggaacgtata aacacattga caagaatcct
      121 acgccaaatc acggatttaa tttaaaaata ggcgatccga agcatttaaa attctttgaa
      181 agtagtattg atctgttaag ttacgctgca ttgaatcggg agaaactaca agatgcctgg
      241 ttagtttcga tggacgggtt aaaacatcat gtaatcagtc attacgttga agagtcgatt
      301 tctgaattaa gacgaaaaca aacatttcct caatcgattg aaatatgtgt ggacaatgat
      361 cgtgcaggac atatttttta tgaaaaagaa cagatgaagg gaatcgttga tccttttacc
      421 aataagaaaa tccgttgtga gcgaggaatt ccaaatgatt ggcaagtacc taaagaatac
      481 aaagctactt atgaagcagt cgcaaaagaa atgagtgttg aacctgaagc aattatggcc
      541 atacacaaaa ctgaaactaa tttacagctg acaaatcaat tggtgtctgc tcatgatgtt
      601 caatctacgt ttggaaagat gttggcgaag ggcgaaccag tagaaacaat tgatttgaaa
      661 gaagcatgta ccacggtcgc gaaggaactg aaagtatgtg aacgcgcaga tggaacatac
      721 aactttgatc gtttttatag tagaaaagcc aacataaaag acgttaatgc aggaatcctt
      781 ctttcctata aagcagaaca atactacaaa ggctataaaa agcatgaaca tgaatttgta
      841 cctgaagtga aaaaggattg gaatgatcaa ttgaagcatg agatccagca acaagaaatc
      901 agaaagcaaa aacgtgcgat gttgtttcaa caaggcagac aacaagaaag ggagtgaagt
      961 cgtcactatg aaaaccgtca ttttagcaga aaaaccgtca caagcgaagg cttatgccga
     1021 tagcttttct aaagctaccc gaaaagatgg gtattttgag atccaagatc gattgtttac
     1081 aggagaaact gtgatcacgt atggttttgg tcatttagtc gagttagatt cgcccgatat
     1141 gtacgatgaa aaatggaaac aatgggcatt agaacatttg cctattttcc ccaatcaata
     1201 ccactatcat gttcctaaag ataagaaaaa gcagtttagt gtcgtcaaac gacagctgca
     1261 gtcagctgat acgattgtga tcgcgactga tagcgatcgt gaaggggagc tgattgcctg
     1321 gtcaatcatt caacaagcag gcgccaatca aggaaaaacc tttaaaagac tttggatcaa
     1381 ctccttagaa aaagaagcca tttatcaggg attccaacag ttacgagacg cagaagagac
     1441 ctatccaaaa tttgaagaag tacaagcacg tcagatcgcc gattggttaa ttgggatgaa
     1501 cggtagccca ctgtatagtt tactcttgca gcaaaaaggc ataccaggaa gtttttcttt
     1561 aggtagagtc caaaccccaa cactctatat gatttatcaa ttgcaggaaa agattagaaa
     1621 cttccaaaaa gaaccatatt ttgaaggaaa agcccaagta atcgctcaaa atggcgcatt
     1681 tgatgcgaag cttgatccaa atgaaaccca agcgacacaa gaagcatttg aagcctattt
     1741 aaaagaaaaa ggtgttcaat taggaaaaca gccaggtacg atccttcaag tcgaaacaga
     1801 gaaaaaaagt gcggctagcc cacgtctttt ttctttatcg agccttcagt ctaaaatgaa
     1861 tcaactcatg aaagctagtg ccaaagatac tttggaagcc atgcaagggt tgtatgaagg
     1921 aaaatatcta agctatccgc gaacggatac cccttatatt acggaagggg aatatgcgta
     1981 tctgttggat cacttagacg aatacaagca ttttttaaaa gccgaagcga ttccgactcc
     2041 tattcataca ccgaatagtc ggtatgtgaa taataagaaa gtccaggaac attacgcgat
     2101 cattcctaca aaaacggtta tgacagcagc ggcttttgaa caactaagtc cactgcagca
     2161 ggctatttat gaacaagtgt taaaaacaac ggtggccatg tttgcggaaa agtataccta
     2221 tgaagaaaca acgatcttga cgcaagttca gcagcttcag ttaaaggcaa tcgaaaaggt
     2281 gccgctagat ctaggttgga agaagttatt tggaaaagag agcgacggaa aagagaagga
     2341 agaagagccg ctacttccta aagtgacaaa aggagaaatg gtgacggtgg atctacaagt
     2401 tcttgaaaaa gaaaccaagc caccacaacc ttataccgaa ggtacgttga tcactgcaat
     2461 gaaaacagct gggaaaaccg tggatagtga agaagcgcaa tccatattga aagaagtgga
     2521 aggaatcggt acagaagcga cacgggcgaa tattattgaa accttgaaac aaaaggaata
     2581 tatcaaggta gagaaaaata agctcgtggt gacgaataaa gggattttgc tttgccaagc
     2641 cgtggaaaaa gagccgctgc ttacgagcgc cgaaatgacc gccaaatggg aaagctactt
     2701 gttaaagatc ggtgaacgaa aaggaacaca aaccactttt ctagccaata tccaaaaatt
     2761 tgtctctcac ttattggaag tcgtaccagg gcaaatccaa tccactgatt ttggatcgac
     2821 gttacaagaa gtgaaagcag ccagtgaaaa gcaagaagcc gcgcgtcatt taggaatttg
     2881 tccaaaatgc caggaacaag aagtcttact ctatcaaaag gtggcagctt gtacgtctga
     2941 agcctgtgat tttaaaaggt cagaagggtt catttgaagc aacgattgtt ttaaaagaag
     3001 acttcactac aggctttgaa ttttctgaaa agaaaaaaac gaacttcaag aaaagaacac
     3061 gccgcactgc aaaataatgg agggttaatc ttatgcgtaa taccacacac aaacaacaag
     3121 aaatcgaaaa tcaaaaagcc aaaattcgtt cagaacagga aaaaatgcgt gccagcaaac
     3181 gaagactgca gcaattgaag aaccagcaga ggattcaaaa agaaatcgaa ttagatcgat
     3241 aaaatcttcc taactattgt atacgtataa acttatgtta tactgttttt ataagtttat
     3301 acgtatacaa aggagggaga aaatgacaaa agcaatggta tacaagctgc tagaagaatt
     3361 taatggaact ttggctttga aggatgccaa aaaagcgggc atttctcctg taacgatcaa
     3421 acgtatggta gatcgagggg agctggatcg agagtatcca ggttttttca ccttacctgg
     3481 tcaatttcct gatgaattgt ttatggcgca aaaaaaatat gaacgcggca ttatttcaca
     3541 tattaccgcg ttagatttgt atgatttaac agatatgatc cctagacaga tcgatctgac
     3601 tgtaccttac ggttatcacg tttctgaaaa aggattgaag gaattcgcag ttgagctaca
     3661 ctatacaaaa gcggaatggt atgaattagg taagattgaa ataaaaagtc gctatgggaa
     3721 tcctattata gcttatgatc cagaaaaaac cttgtgtgac atttggaatc cctggtataa
     3781 cgttgaggat gaaatcaaag taaaagcaat caaaaactac atggagtcgg acagaaaaaa
     3841 tcttagaaaa ttgaatgagt atcgacgaat tttgcctaca gataaaacga tgcgctctta
     3901 tattatggct ttaaattaaa ggagaataca catgacacct acgcaattaa aagcaaaagt
     3961 gaagaatatt tctagagaaa aagaagttga tccgcagctt gttttaagac attttatgat
     4021 ggaaaaattc ttggaaaaaa tctcagagtc tccttatcgt gaaaattttg tgttaaaagg
     4081 cggcttctta attggctcaa agtatggcat tgaaaatcga acaactaaag acattgatac
     4141 gactttacgg gaaatgaaag taaccaaaga aacattgaca acggttctaa acgatatttt
     4201 ttcaacgccg acgaaagaag gcattcaatt tgagattcaa ggaatgaaag aaacgaggga
     4261 agctgattat tatccagggt ttagcttacg tgtactggca catttggaaa acatgcggcc
     4321 agattttaag gtagatgtta ctacaggtga ctcgatctat cctgcgacga tcactcacag
     4381 tcataaattg atgtttgagg atcgaacgat tcctttggaa tcctatccta cagaacaaat
     4441 tattgctgaa aaattaagtg caacctttga ttttttaaca gataattcga gaggaaaaga
     4501 tttttatgat ctctatacta ttcctaaaat ggagaagatc gatgagaaga ccttgaaaga
     4561 tagtgtgaga aatacattta cacgtcgagg aaaaactgat ccgttaaaga tatactatga
     4621 aaaggatatg gatgtactga aaaatagtca cgagctaaaa gatacctgga agaaatatca
     4681 aaaaagcaat ccttatgctg cgtcgatcac gtacgatgag acaatggatt cgattagtaa
     4741 tttgatggaa aaagtgattc acgtcgaaga aaaagagcga aaactagctt atcaaagaca
     4801 ccaacagatg aatagagaaa tggagagata aagatgatta ataatgtgac attagtagga
     4861 cgcttaacca aagatcctga tttacgttat accgcaagtg gtactgcagt agcgactttt
     4921 accctagccg tcaaccgaaa tttcacgaat caaaacggca attgagaagc cgattttatt
     4981 aactgcgtga tttggcgcaa accagcagaa acaatggcga cattagctaa aaaaggtagc
     5041 ttgattggtg tagttgggcg gattcaaacg cggacttacg acaaccagca aggacaacgt
     5101 gtatatgtga ctgaagttgt agcagataac tttcaactat tagaaagtaa agcagcgaca
     5161 gagagccgtg cgcacgctga tcaatcgtcc accagtccaa gcaccgccac ctttgaacaa
     5221 cggaatacag cgacgcctaa caacaatgga ttgaacgctt cacagaatcc atttggtgga
     5281 caatcaatcg atattagcga tgatgatcta ccgttttagt ttgagaaaga aggagtaagc
     5341 atggcaaaaa aattagtctg acgatggatc tattgatacc cgtaattgca tttatagacg
     5401 ggatttcttt gggcgtcact gaaaatcctt tggtaaatag aattgcgaaa ggatcactat
     5461 ttcttgtatt cgtgtatctt gtctgttctt atcttttaaa aagagcagga aaggataatt
     5521 ccttttggcg attgactaaa gtcacagtag cagcgacagc tgttatactt acggctattc
     5581 taccgcttta tatgtagagt taacgggaaa tcgttgaact tcttgcgaaa tattgctata
     5641 atgaacatga aaaagaggag ttgcgctaac aacccctcat taacagcacc gattaaagaa
     5701 cggtggcaga atattagtta tttggaaata accgctgacc tgctaaagta gacggttatt
     5761 tctttttgtc atttttaagc atatttacaa tcaaactaat caaagcaatg gtaaacatac
     5821 caaaaccaag aatggtttga attgtctcat atgcggacaa aaggcttact cctttcatag
     5881 attttagcac ttacattcat aagcaccacc acctttccag aagtcgccac cgtcttcaaa
     5941 ctttactgtc ttgactatta tagcatatct aaaatcgaat aaaaattctc aattttagct
     6001 gtttttgcta taattttagc gaggtgatcg tgatggaaca atatattggt ttactcgata
     6061 aattagggtg atcaagacac agccattgct tgtgcgattt acattacgca cgagtcatga
     6121 accaatcaat tgtgtagtgg ccaatataga aatagcggat aaattgctga ttttggaaga
     6181 aggcaagtat actatttcag tgacaggtca cttcaataaa cgaaagcaac tagtcattga
     6241 atcaatgcaa attagaaacc ctgatcattt tacgcgatcg atgagcatat aaaagaagag
     6301 ctgcagtcct aaatgaggat tgtagctctt tttgttttac atagaaacag taaaaatgaa
     6361 aaggcctgtt taggaaggca caagcgcctt ctcaattgaa agacctttct ctcactccaa
     6421 ccgccaccgc cgttcgagaa gaaaggaagt gaacgctacg cgttcactaa gataaagggt
     6481 cttgcatagc aagacaaaat agaaaaaatt tcctctcacc aaaaggttcg ctcctgttcg
     6541 ttatctcttt attgatttgt cagaccggca acaagttgcc ttttatcacc aaaaagcgac
     6601 aaggacaagg gtaaatggca cgctgcgcgc ccttgtcttg tcgcttttcg ttgattcatt
     6661 ctggccaaca aatcaataaa gaaagaacta acgaaaggaa gtaaaacctt tcctaagagg
     6721 aggcagaatc aatcatgcga aagaaatttg attattgggg tgttcccttc agcgaattat
     6781 tcccaaacta tcatgcacca catactgtcg aatgcgattg tggagaaaga gcgaaatgta
     6841 tcaaaagcta ttgtttgtat caatgtccaa catgcgggaa aaaatatacc ttgtcttatg
     6901 gcgattatat tttaattgat gagaaaggaa agaaacgctg atgaaaacac aacacaaatt
     6961 attgactgta aaagaagtcg ttcaaatttt ggtggacaaa gaagtcattt ctgaaaaagt
     7021 agcagaagtt ttacttattc cgcggtactg gacgatagaa acccctttag tagaggatgc
     7081 accgactatg ctatttgaag acctagtgaa gattgcagga tatgaactgc attatcaaga
     7141 aaacttggaa acttatgaaa acgaatattg gttaaccaaa ttagagaact aaaaaggaga
     7201 aaaaaatatg gctcaaaatt actatgacga atttgtcaaa ttacctttgg ataaaatggc
     7261 acaaaaaatg gaggatatga cgttcctata caacgaaaca cgtgttccaa aaaaacatta
     7321 taaagaaaaa ttgtcggtag ctgtggaaga aatgattgaa taaggtgtcg aaatgaatct
     7381 tattgcgacg tactatcgaa cactggaaga actgaaaaag caaaatgcaa aatggttttt
     7441 ccaagcctta ctatgcttgg aagtaggtgt caaaccaagc actattaaac cttctgaata
     7501 ccaagcttta gaactaacgt atgcgaaatt tatcgaaacg aaaaaagcca agactgtttc
     7561 aagtgaatgg ttagattatt ttgaaaatat caataagtat ggcgcatatt acaccatgaa
     7621 aaaggaagac aacgaaaatg aataaggtga tttatcaact aacaacggat tccatatcaa
     7681 cgatttgaaa gaaaaaaagg tcaataatca tttataccga aaagtgagaa tgtgtgaaac
     7741 aaggacaaaa aacgcctagt aactaaggaa atggttctta tttcgcacca atcgctccaa
     7801 ccgcccccgc cgcttaggtg gtgcgaaata aacgggcaaa gcccgataac ttaagagaaa
     7861 gaaggtgatc catttgaaca agattattcc cttattgtta gtactgtttg ttggcgaaat
     7921 acttatgcga gatagtgcag ctgtacagtt aaacctcgct gtatttttgg taatactggt
     7981 gttttgtttg atcttttggc ggtttgtatt agtcctcgtg agtctactat tcaagatgat
     8041 tgcagccata tttttcatag ggttatttcg atgaaaggag tgagtaccaa tgccaattgc
     8101 aataggaaat aaacggttac ccgtgacatt agatgaaaag agacaaaaag aattgcagca
     8161 actaaagcag aagtatggca aaagtgaatc taagattatg tgtattgcgt tagatctatt
     8221 gatcgcgcaa gaaaaagcag gatttgatgt accagcgcta aaaaagtgac gtcacttttt
     8281 aatttgatct atataagtga tatcactttt accaaggagg gaattaaatg ttaaaaacta
     8341 aaaagaattc gtacaaatta aagcttagta tactatctat tatttgtctt ttaggcatga
     8401 taattagtgg tcatttgtat agagtggcat atacgcagtt tattgagtac aaggttcact
     8461 ctttaggatt agctggggat cgatacgttg aatatgtcca ttattcatta aaatgttctt
     8521 catatattct tctttggctt attttttcat tgtttgaatt gctaaattta atagcaatat
     8581 cttcatatca cttagataag ctaaatacca aatctagccg ttataacgaa gtgtttaagg
     8641 aaaatgtgaa gttagaaagt gacttaaaca agctaaaaaa ataaaaagaa gaaaacataa
     8701 gttaactaaa attattttat taagaatgat ggaatataag gataaggtta ccaacataac
     8761 gatcattact tctctgatat gctatggact tctatcaatc agtattttgt ctatagatta
     8821 tggagtaact atactgcaag ccttagtttt ggctatgcct atgtatctat ctttgtttat
     8881 catgcatgaa atatataagc tatttgtttt atcaaaaaat gtagaaatac gggtaaatat
     8941 tttggtgaat agttatcaaa aagaactcaa agaaagaaga cggtggcggt atttattgaa
     9001 aggatgaaaa agtaggattt gacatactgg tattcagaaa gtgccgtcac ttttaaaaca
     9061 atggaaaagg tggagataag atgaagaaaa aacaaactaa actatcatta gcagatattt
     9121 aacacagtta accgcaactg aagatggtgt tgttgaattt gaacaatctg aaattgcggt
     9181 agtagatgat cgttacctta aaatgcctta cttctttgac caagcaaagg tcatttgcct
     9241 ttgtcactac gatggggtac gtgattttag gcgttaaaaa gtagtgatta tatcaacttt
     9301 acgagtaaat ataaatttag acatgaaact gaattatcca atggaaaatc atggtttata
     9361 atctagaaaa attatagtaa tgattggatt atatatattc tttcgtattt tcgtacaact
     9421 gtagcttgtc aaaattgaga aatttaaccg attaggtact ttacatcgtt atttgggtaa
     9481 tttctaaaac atgaagctta ccaacgaata aactgagact atcttattaa ttgatcaata
     9541 taagaaaata tctttgagga gatgatgtac tatgttttcg tctatccacg attggttagg
     9601 tggtcttttc ggcggtggag gtaaaggttt tta
//
LOCUS       DAFEKH010000082         9615 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.085, whole genome shotgun sequence.
ACCESSION   DAFEKH010000082
VERSION     DAFEKH010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9615
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.085"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            9..851
                     /locus_tag="LP386_002613"
     CDS             9..851
                     /locus_tag="LP386_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBL1919809.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVTVVLFFKELLIT
                     SFDPLMAKAMGMNVSFYHYLLMILLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGACSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERKL"
     gene            851..1798
                     /locus_tag="LP386_002614"
     CDS             851..1798
                     /locus_tag="LP386_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBL1919810.1"
                     /translation="MRKWKAVLGSLGILIALFIFGACSTNSKDKDTVASNEKLKVVVT
                     NSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETGG
                     NAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKNI
                     EKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYFS
                     KAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDTN
                     IPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            1813..2046
                     /locus_tag="LP386_002615"
     CDS             1813..2046
                     /locus_tag="LP386_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HBL1919811.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            2377..2961
                     /locus_tag="LP386_002616"
     CDS             2377..2961
                     /locus_tag="LP386_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL1919812.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLV
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            3092..3760
                     /locus_tag="LP386_002617"
     CDS             3092..3760
                     /locus_tag="LP386_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBL1919813.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFGTSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            3771..5186
                     /locus_tag="LP386_002618"
     CDS             3771..5186
                     /locus_tag="LP386_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBL1919814.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            5204..5773
                     /locus_tag="LP386_002619"
     CDS             5204..5773
                     /locus_tag="LP386_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HBL1919815.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVVSWVLMQLGSAAGQWIPIWFFTDRFRQDWIDRGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            5883..7637
                     /locus_tag="LP386_002620"
     CDS             5883..7637
                     /locus_tag="LP386_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1919816.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQYLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHRVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            7597..9363
                     /locus_tag="LP386_002621"
     CDS             7597..9363
                     /locus_tag="LP386_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1919817.1"
                     /translation="MQMIGGLTMKNFYKKKFALTDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENAKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVTMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
BASE COUNT         3345 a         1259 c         1757 g         3254 t
ORIGIN      
        1 ggaataatat gcttcaaaat tttattaatg gtctgtatga ctttcacttt ttacagaatg
       61 ctctaattac atctgtagtt atagggattg tttctggaac agtaggttgt tttattattt
      121 taagaggaat gtctcttatg ggtgatgcta tttctcatgc tgttttgcca ggagtagcaa
      181 tttcttatat tttaggtatt aattttttta ttggtgcgat tgtatttggt ctattagctt
      241 ctatcattat tacttttata aaaagcaata gtgtaataaa aggagataca gcaattggta
      301 ttactttcag ttctttttta gcattaggag ttatccttat aggagttgca aatagctcaa
      361 cggatttatt tcatatctta tttggaaata ttttagctgt acaagatatt gataagtgga
      421 ttacaattgg cgtttctgtt ttagtgttgg ttacagttgt tctatttttt aaagaattat
      481 taatcacttc ttttgatcca ttaatggcaa aagcaatggg gatgaatgtc agtttttatc
      541 attatctatt aatgattcta ttaactttag tagcagtaac agctatgcaa agtgtgggaa
      601 ctatattaat tgttgcaatg ttaattacac cagctgctac agcatattta tatgcaaaca
      661 gcttaaaaac tatgatattt atttcggcga cagtcggagc gtgctcatca ttgctaggtt
      721 tgttcattgg ttatagtttt aacatagcag caggatcaag tattgtttta acagcggcat
      781 tcttatttgt aattagtttt ctaatctcac caaaacaaaa atttttaaga aagaaggaga
      841 gaaagttatg atgagaaaat ggaaagcagt actgggaagt ctggggattt tgattgctct
      901 ttttatattc ggggcatgtt caacaaatag taaagacaaa gatacagtgg cttcgaacga
      961 aaaattaaag gtagtagtta ctaattcgat tttagcagat attactgaaa atatagcaaa
     1021 agataaaatt gatttacaca gtatcgtacc tattgggaaa gatccccacg aatatgaacc
     1081 tttgcctgaa gatgttcaaa aaacttcaaa agcagatttg attttttata acggtgttaa
     1141 cttggaaact ggaggaaatg cttggtttac aaaattagta aaaaatgcga acaaagagga
     1201 aaacaaagac tattttgcag caagtgatgg catagatgtt atttacttag agggtcagag
     1261 tgagaaaggg aaggaagatc cccatgcttg gttaaattta gaaaacggta ttatttacgc
     1321 taaaaatatt gaaaaacagt tagcggaaaa agatcctgat aataaaaaat tctataaaga
     1381 aaatctagat aagtatattg aaaaattgga ttctctagac aaagaagcta aatctaaatt
     1441 tgcttcaatt ccgaatgata aaaaaatgat tgttacaagt gaaggatgct ttaaatattt
     1501 ctcgaaagcg tataatgtgc cttctgctta catttgggaa atcaacactg aagaagaagg
     1561 aacaccagat caaataaaac acttagttga aaaattacgc acaacaaaag ttccctcctt
     1621 attcgtagaa agcagtgtgg acgatagacc aatgaaaaca gtatcaaaag ataccaatat
     1681 tcctatctat tcaacgattt ttactgattc aattgcagaa aaaggacaag atggtgatag
     1741 ttactatgcg atgatgaaat ggaacctgga taaaattgct gaaggccttt cgaaataatt
     1801 tggagggtag gtatggtaca aattaaaacg actactatac taatttattt actagcaatt
     1861 caggaattat caaaaagaaa aaagaaatta aaaaataatg atttagcaaa agttctaagt
     1921 gttagtccag catctgtaag tgagatgctg gctaaactta gatatgagga ctatttagat
     1981 ataggatttc aattaactga taaagggaaa aaatttattg acgattacaa aaaaggtttt
     2041 aagtaaaaga ctttattttt agggaggata agaaaatggc tattggagtg attatgatag
     2101 gacttaccct aatagctgga tataattttt ttaaatcttt ctcggattat tttagaaaag
     2161 gtgaatgatt tagatgagtc tattaattct tgtaggattg ctttttgtat cagttatttt
     2221 gctctttctc attagtttag ctctaaggaa tgagttcagt aatagacgtt aacgattgaa
     2281 acttcaagtc ctgtgtaaga taatatagtt aattcatctt attaggagga agtacccata
     2341 gaaaccagag attatattac aactcaccaa aaattaatag aaagtggact aagccatttt
     2401 gaaaaagaag gatttcagca aactaagata aggcaactgt gcttgaccgc aggcgtaact
     2461 acgggtgctt tttataaaca ttttacttct aaggaagcgt tatttgaaga aattattcag
     2521 ccgcatatta atgcgcttat taatatgtat aatgaagagt ttaccaaata cctcttaaac
     2581 ttagaaaata tagatataga gaaaagttgg agagagaact tcaatgaatt agatccattt
     2641 attaattata tttttgagaa taaacgtata ttcgatttgg ttttattcca atcagctgga
     2701 accaaatatc aagatattgt tgaaaaaatt acatcatttg tgacaaaaaa gacagtctgt
     2761 tgtctagata agttaaagac tatcggaatg atcaatcaaa atttagtctt taatgaagaa
     2821 gaaatccact tctacattta ctcattctac gctacattct atgatatatt gaagcatagc
     2881 tattcaaaag aaaagactat gctattaacc agaagattgt atcaattttc tgttcctggg
     2941 tggattgaat tactgagtta attaaaaaaa agcttgcatt gagaattgtt ctcagttatg
     3001 ctttttgata agatcgcact gttatctgaa taacggtgca tttttgtcag cttaagataa
     3061 cagtgcgatc ttattttttg gaggtgaaag agtgtcaaaa atcaatccgt taaccttgat
     3121 tactttaaat attttttttc cggtcattat ttttttagga aagggaaata tatttcaagt
     3181 ggggtgtttc attattgcta cagttttagt attgatgttt cgtaaaataa agacatgtat
     3241 ttatttcatc ttgatttatt cagttctgtt tttagtaatg aaaattattg atgctatcaa
     3301 gatagagttt tttactatat tttttgggac atccttatat attgtatttc gaatgttgcc
     3361 ggtcgtaatg atctcatggt tgttggttag tgtctatact agcaatgaat tattatcctc
     3421 tttagaaaaa atacatttac cgaaaaaaat aatgttaagt attacagtag tgatcagatt
     3481 ctttccgact tatcgttctg aaataagaat gattaaagaa tctttaaaaa tgagaaacat
     3541 tcgcttgtct ttttttcagc ctctgcaata tttggaattt ctgttagttc ccgttcttat
     3601 acgtgcaact atgattgctg aagaaatgac cgctaatgca ataacaaagg ggatagaatc
     3661 tcctgtgaaa agaagttctt actataaaac aaacatgagc ttattagact atatcatcct
     3721 gttttccgtt actatttttt tcttaagtat tttgatttga ggtgaaagaa ttgtttgaat
     3781 ttaacaatgt ttctttttca tataaggatg ttaaggaaca agcgcttgtt gaccttaatt
     3841 tttcaataaa aaaaggcagt cttacattga ttactggttc ttctgggagt gggaaatcca
     3901 cactattaaa gttaatgaat ggacttattc caagacttta tgacggaaaa ttggttgggg
     3961 aaattttatt tgaaaataac tcgctacaat ccttaacaca agaaagtata tcaaaaaata
     4021 ttggctacgt aagtcaagat cctagaggac aattctttac aacaaataca acgagtgagt
     4081 tagtattttc gatggaaaac tttggattta caaaagagca tatggataaa agaatcaatg
     4141 aattagctga attattagat ctttcaaata tattagataa aaacattttt tcgctatcaa
     4201 gtggtgaacg gcagaaaatt tctattggat gtagtttatc gctaaactct aaattaatta
     4261 tattggatga accgtcttca aatttggact tcaaagcgac taagaaactt gctgacttac
     4321 tttgtgattt aaaaaataaa ggatttacta ttgttatagc tgaacatcgt ttttactatt
     4381 tgaaagaatt aattgatcaa gttctatttg ttaaaaatag aactgtaaaa actacaacta
     4441 ttcagttgtt aaaaactgaa aacaataacg cattaaggaa atttgacatt tttaatagtt
     4501 cgattgaagt tccctatatc gaaaaggtaa gtgcagatgt attaaaagtt gaagaaatta
     4561 cttatgaaaa tattctaaaa gacataaatt ttgatgtcaa agttggagat gttattggtt
     4621 tggtagggaa aaacggtgtg gggaaaacaa ccttactaag aatactcatg aagattattc
     4681 gccctaccaa aggaaagata atcgaaaata aaaaaaattt gtcatcgccg tttttagtaa
     4741 tgcaagaaat ggattaccaa tttttcacag aatcagtgag gagcgagtta gccctgggga
     4801 atgaaatagt tagtaaagat cagcaagaaa aaattttaaa aaaaatggaa ctttataaaa
     4861 tgaaagatca attaccgttt gatttatccg gtggagaaaa acaaagatta ttggtttcta
     4921 tagcttcatt gtcaaaaact aatttatttc tatttgatga acctacaagt gggttggatt
     4981 atatcaatat ggaaaggatt gctgacctta ttaaagactt aaaagaaaag ggtgcagtag
     5041 ttatagccac tcatgatccg gaatttcttt ataaaacatg caatagaatt atttatttaa
     5101 aaaatggtgg aataaaaaaa gatataaaac ttagagtaga agattcaact ttgatagaac
     5161 agatttttaa tgacataacg aaatagaatt gaggagaata tatatgaaaa caaaagatta
     5221 tatttttatt ggtttagcta cagttatttc cctagtaatt tacttttttt caataatggt
     5281 tagtagtatt ggtggggcgt ttggtcacag catatcccca gggatttttg gattattatc
     5341 tggaatcata tttgtttata ttagctataa ctaccctaga aaaggaattt ttactattta
     5401 cacaattgtt ttattgttat tttttacgtt aatgggcggg gcgtacttac cttggtttat
     5461 cagttcgatt agtatggcga tcttagctga tattattcta tctgtatttg gatatgatcg
     5521 agcaattcct caagttgtgt cttgggttct aatgcaacta ggcagtgctg ccggacagtg
     5581 gattcccata tggttcttta cagatcgttt tcgtcaagac tggatagata gaggacaatc
     5641 tgctgcaaca atggatgcaa tgatccacta cgcggtgggt atatggggaa ttatttcagt
     5701 gttagttgta gcaagtttat ctatgattgg tgtattgatt ggaagaaaag tcttaaaaaa
     5761 atacaaaaaa tagaacgtag tttaccttct atctgtttgt acatctctaa tttacgctat
     5821 tacggaaagc attaacagtt gtaaacgaat aagagaagaa attgaatgcg ggggaggaaa
     5881 aaatgaaagt atacaaaaaa ttatttagtt atgtccctaa aatgaaatac tacggatggt
     5941 tagccacttt attttctgat ttttctgtcg tattaacagt ctatggatat tacagtattt
     6001 acaaatttct tcagtctcta attattgtag gagatgaata tttagctaag agttatgcgg
     6061 ttcaaactgt tgcttggtta actttaggag ctttatttta tattttttct ggcttatttt
     6121 ctcatatcct tgggtttcgc ttagagacta atttgagaaa aaagggaatt agcggtttaa
     6181 cagaagcaag ttttcgtttt tttgatttaa attcttcggg atatattcga aagacaattg
     6241 atgacaacgc ggctaaaaca catatggcaa ttgctcactt gattccagat agtgctcaag
     6301 ccatagtaac acctgtttta tcagttgcct taggcttttt cattaacttt aaaattggat
     6361 tggttctaat cgccatgtta gtaattggtg tattcttgtt aaagaaaatg acagagaata
     6421 caaattttat tcaaaaatat caagaatcgt tagatgtgtt aagctctgaa acggtagaat
     6481 atatccgcgg aattcaagtt ataaagatat ttggtgctaa agtaacatca tttaaagcct
     6541 tgaataaagc aattaacgat tatgctaagt ttgcatataa gtattctttg agtgggaaaa
     6601 caccttttgt tctttttcaa tggctatttt ttggcatagt ttgcattttg atagttccta
     6661 taaccttttt tataacttct cttaccactc ccaagatatt agctgttgac ttgttgatgt
     6721 tgtttttttt aagtggaatt atttttgttt ctttcatgag aataatgtat gtaagtatgc
     6781 acttgtttga agcaagatat gcagtcgaaa cactagactc cctttattta gaaatgaagc
     6841 aagaccaact aaaatatggg aacgagacac agattaaaaa ttgtgacatt gcatttgaaa
     6901 atgtcagctt ttcatacaaa gaagagtgtg ttttagaaaa tttcaactta gttttagaac
     6961 aaaaaagaat ttatgcatta gtaggaaaat caggaagcgg aaagagtacg atagctaaac
     7021 taatttcagg tttctacaat gtggataagg gacagattaa aattggtggt aagcctttaa
     7081 atcactattc aaaagacaca attattaaca caattgcttt tgtctttcaa gatacgaaac
     7141 tattcaatca gagtatttac gataacgttt ctatagcaaa tcctcaagcg ccagcaagta
     7201 aagtatttga cgcgctaaga ttagccggtt gcgaatcgat tttagaaaaa tttcccgaaa
     7261 gagagcatac cttaattggt agtaaaggag tttatctgtc aggaggagaa aaacaacgta
     7321 tagctattgc cagagcaatt ttaaaagatg caaagattgt tattatggat gaagccagtg
     7381 catctattga tccagataat gagtatgaac tacaaaaggc ttttcaatat ttgatgaaag
     7441 aaaaaacagt tattatgata gctcatcgat tatccagcat taaatctgta gatgaaattc
     7501 ttgtcttgtc agaaggaaaa atagtagaac gtggaaatca taatgaatta atggctaaac
     7561 atcgagtgta taaacaattg gtcactaatt atgagaatgc aaatgattgg aggcttgaca
     7621 atgaaaaatt tttataaaaa aaaatttgct ttaactgatc agggcgcaga agctttaact
     7681 aaagcttcta tttctagttt ttttgtatac tgcattaata tggtaccagc attcattata
     7741 atgatgctga tagacgaatt agttttagaa aatgcaaagc cccgttggct ttattttgca
     7801 gtatcgtttg ttactttgct tttcatgtat tggttgttag atagggagta tgaaaactta
     7861 tataatagta cttataaaga aagtgcgcat ttaagagtgc aaattgcaga cgatttgtca
     7921 aatttaccat tatcctattt ttcaaaacat aatttatcag atttatctca aactatcatg
     7981 tctgacgttg aaggtattga gcatgcgatg agtcatgcaa tacctaaagc cggcggtatg
     8041 gctctgtttt tcccttttat ttcagtgatg cttttggttg gtaatgtcac aatgggatta
     8101 gctgttattt tgccaacgtt atttagtttt gtcttaatct tgttatcaaa gaaatcccaa
     8161 acgaaagcca atactaaata ttacgatact ttgagagaaa actcggaaga atttcaagaa
     8221 actattgaat tgcagcaaga gattaatagc tttaatctat ctaaaaaagt tcaagacaga
     8281 cttttcaaaa aaatggaaga gagtgaaagg attcatttaa aggtagaatt aagtactttt
     8341 tcagtcatgg ccttatcctc tattttctca tatgttagtt tagcagtagt cattctagta
     8401 ggtgttcact tactgttaac gggtgaagtg actatactct acgtcgttgg ttacttacta
     8461 gccgcaataa aaataaagga ttccttcgat tctatgaaag aagcagtgct tgaaatattt
     8521 tatttagctc ctaaaataca gcgaattaga gctatgaagg aaaccagtat ccaagaggga
     8581 tcagatagtc ctctgaaatc ttttgacatt gagttgcgag atgtctcttt ctcatatgat
     8641 aacaataccc caattttaga tcatatctct tttacggcta aacaaggaga agtgactgcg
     8701 ttagtaggtg ctagtggttc cgggaaaact agtatcttga aattagtgtc tagactgtat
     8761 gattatgatg aaggctgtat tttaattgat gggtatgata ttaaacgtgt atctccagct
     8821 tctttgttta gcaaaatcgc tattgttttt caagaggtaa ctttgtttaa tacaagtatt
     8881 ttggaaaata tacgtattgg aaatagtcaa gcgtcagatg aggaagtgaa aaaagcagct
     8941 cgtttagcta actgcgaaga ctttattgaa aaactacctg acggttatca tacattggtc
     9001 ggagaaaacg gaagttcact ttctggagga gagcgacaac gcctatccat agcacgggct
     9061 tttttgaaaa atgcgccaat tttaatttta gatgaaatta ctgccagttt agatgcggaa
     9121 aatgaaaaac gtattcagga aagtttaaat cgtttaatac aagataagac agtactaatt
     9181 atatcgcatc gcttgaagtc tattgaaaag gtaaataaaa ttgtagtgat ggatcaagga
     9241 aaactagttg atcaaggtac tcataatgag ttgtatcgaa ggtcagaaat atacaaaaat
     9301 ctcataaaga aaactaaact atctgagaaa ttcgtctatg aaaaagaagc tcaatcacga
     9361 tgatgaaata ggctttaaat taacctacaa tttttgggat atagttataa ttctttttca
     9421 aaaagaataa ttttattaaa cagcatctaa ttttgaatac acgaaagaat cagtatgatt
     9481 gaattagttc acttaatgtc tattcttata atataaggaa taatcaaagt tttaaaaaat
     9541 tggcgataaa ccagttaaac ataaaagatt gaataaaaag ttatagtttc tttcatattg
     9601 ccgttttaag tagag
//
LOCUS       DAFEKH010000083         9387 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.086, whole genome shotgun sequence.
ACCESSION   DAFEKH010000083
VERSION     DAFEKH010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9387
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.086"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            2..77
                     /locus_tag="LP386_002622"
     tRNA            2..77
                     /locus_tag="LP386_002622"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            79..149
                     /locus_tag="LP386_002623"
     tRNA            79..149
                     /locus_tag="LP386_002623"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:111..113,aa:Gly,seq:tcc)
     gene            163..236
                     /locus_tag="LP386_002624"
     tRNA            163..236
                     /locus_tag="LP386_002624"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:197..199,aa:Ile,seq:gat)
     gene            261..348
                     /locus_tag="LP386_002625"
     tRNA            261..348
                     /locus_tag="LP386_002625"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:295..297,aa:Ser,seq:gct)
     gene            370..441
                     /locus_tag="LP386_002626"
     tRNA            370..441
                     /locus_tag="LP386_002626"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:403..405,aa:Glu,seq:ttc)
     gene            464..553
                     /locus_tag="LP386_002627"
     tRNA            464..553
                     /locus_tag="LP386_002627"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:500..502,aa:Ser,seq:tga)
     gene            566..639
                     /locus_tag="LP386_002628"
     tRNA            566..639
                     /locus_tag="LP386_002628"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:600..602,aa:Met,seq:cat)
     gene            658..730
                     /locus_tag="LP386_002629"
     tRNA            658..730
                     /locus_tag="LP386_002629"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:691..693,aa:Asp,seq:gtc)
     gene            734..806
                     /locus_tag="LP386_002630"
     tRNA            734..806
                     /locus_tag="LP386_002630"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:767..769,aa:Phe,seq:gaa)
     gene            811..881
                     /locus_tag="LP386_002631"
     tRNA            811..881
                     /locus_tag="LP386_002631"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:843..845,aa:Gly,seq:tcc)
     gene            894..967
                     /locus_tag="LP386_002632"
     tRNA            894..967
                     /locus_tag="LP386_002632"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:928..930,aa:Ile,seq:gat)
     gene            979..1050
                     /locus_tag="LP386_002633"
     tRNA            979..1050
                     /locus_tag="LP386_002633"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1012..1014,aa:Glu,seq:ttc)
     regulatory      1239..1318
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            1316..2509
                     /locus_tag="LP386_002634"
     CDS             1316..2509
                     /locus_tag="LP386_002634"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HBL1919818.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            2639..4111
                     /locus_tag="LP386_002635"
     CDS             2639..4111
                     /locus_tag="LP386_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL1919819.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            4194..4982
                     /locus_tag="LP386_002636"
     CDS             4194..4982
                     /locus_tag="LP386_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HBL1919820.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(5049..5717)
                     /locus_tag="LP386_002637"
     CDS             complement(5049..5717)
                     /locus_tag="LP386_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HBL1919821.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            5832..7544
                     /locus_tag="LP386_002638"
     CDS             5832..7544
                     /locus_tag="LP386_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1919822.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            7547..9319
                     /locus_tag="LP386_002639"
     CDS             7547..9319
                     /locus_tag="LP386_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1919823.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
BASE COUNT         2767 a         1643 c         2121 g         2856 t
ORIGIN      
        1 tggttccgtg gtgtaggggt taacatgcct gcctgtcacg caggagatcg cgggttcgat
       61 tcccgtcgga accgccatgc gggtgtagtt tagtggtaaa accacagcct tccaagctgt
      121 tgtcgcgagt tcgattctcg tcacccgctt ttagtttttt atgggcctat agctcagctg
      181 gttagagcgc acgcctgata agcgtgaggt cgatggttcg agtccattta ggcccattag
      241 tacaaaatct tattggtttt ggggaagtac tcaagtggct gaagaggcgc ccctgctaag
      301 ggtgtaggtc gggaaaccgg cgcgagggtt caaatccctc cttctccgtt tcaatatttt
      361 gttttacctg gcccgttggt caagcggtta agacaccgcc ctttcacggc ggtaacacgg
      421 gttcgaatcc cgtacgggtc attaatttaa tatagtttta catggaggat tacccaagtc
      481 cggctgaagg gaacggtctt gaaaaccgtc aggcgggtaa aaccgtgcaa gggttcgaat
      541 cccttatcct cctttttcat attatcgcgg gatggagcag tctggtagct cgtcgggctc
      601 ataacccgaa ggtcgtaggt tcaaatcctg ctcccgcaat taaaaactaa aaacattggt
      661 tccgtggtgt aggggttaac atgcctgcct gtcacgcagg agatcgcggg ttcgattccc
      721 gtcggaaccg tttggctcgg tagctcagtt ggtagagcaa tggattgaag ctccatgtgt
      781 cggcagttcg attctgtccc gcgccattat gcgggtgtag tttagtggta aaaccacagc
      841 cttccaagct gttgtcgcga gttcgattct cgtcacccgc ttttagtttt tatgggccta
      901 tagctcagct ggttagagcg cacgcctgat aagcgtgagg tcgatggttc gagtccattt
      961 aggcccattt attttattgg cccgttggtc aagcggttaa gacaccgccc tttcacggcg
     1021 gtaacacggg ttcgaatccc gtacgggtca tggaagatac tttttgagta tctttttctt
     1081 tttatctgaa agaatgattt taaaaagctt agcagagtta tctttatgga tgattgtgct
     1141 aagctttttt ggacagttct aatgtaaaat atttttatat tttttaagca aaaaaatgaa
     1201 aaaatacgag cagaaaactg ttttatctgc tatacttggt tcgttgcaag ttcccgaaag
     1261 gatccgcagg acggagatgc cttgtaaccg aatttaacta gggggaatca ttataatggt
     1321 agaaagacac ttatttacat cagaatctgt ttctgaagga catccagata aaattgctga
     1381 ccaaatcagt gatgcaatct tggatgcaat tttaaaacaa gatccaacag cacgagtagc
     1441 gtgtgaaacg tctgtaacaa ctggtcttgt tttagtattt ggagaaatat ctacgacggc
     1501 atatgtagat attcaaaaag tcgtacggga aacaataaaa gaaattggtt atacacgtgc
     1561 aaaattcgga tttgatggag atacagcagc tgtattggtt gcgattgatg aacaatctcc
     1621 tgatattgct caaggagttg atgaagcact tgagatccgg gatgaagata aaaaagacgt
     1681 attagatgag attggtgctg gtgaccaagg tttaatgttt gggtttgctg tagatgaaac
     1741 accagaattg atgcctttac caatcgcttt gagtcatcgt ctggtacgac gcttggcaga
     1801 tttgcgtaaa tcaaatgaat taacgtattt acgtccagat gcaaaatctc aagtaacggt
     1861 tgaatatgat gatcaaggac aaccggaacg cgtagataca atcgttattt caacacagca
     1921 tgatgatgca gtagataatg aaacaattcg tcatgatgtc atcgaaaaag tagtgaagga
     1981 agttattcca gctgaattat tagatgatca aacgaaatat tatatcaatc cgactggccg
     2041 atttgtcatt ggtggtcctc aaggggatgc cggattaaca ggaagaaaaa tcattgttga
     2101 tacgtatggc ggttatgctc gtcatggtgg cggtgctttt tctggtaaag atgcgacaaa
     2161 agttgaccgt tctgccagct atgctgcacg ttatattgct aaaaacattg ttgcagcagg
     2221 gcttgctcgc aaagcagaag tacagctagc ttatgcgatt ggtgttgctc aacctgtttc
     2281 gatctcaatc aatactttcg gtactggaac ggttccggaa gaagaactga ttgctgcagt
     2341 gagagaaaac ttcgatcttc ggccagcagg aatcatcgag atgcttgatt tgcgtcgtcc
     2401 gatttacaaa caaacagctg cttacggtca ttttggtcgt acagatgtag atttgccttg
     2461 ggaacatacg gacaaagtag atgcgttgaa agcaagttta gcaaaataag ttatattcag
     2521 ctggaacgat cgccaagtgg tggttgttcc agcttttttt atggcagtta acctcttgaa
     2581 aaagatagta attatttatc tatttttaga tcctgtcata atgaaaggga ggaataagat
     2641 gaaaaaagaa acaaatgtta ctttggtcac agtgagtatt ttcattgcaa cgttcatgac
     2701 ggctattgaa ggtacaatcg taacaaccgc tatgccaacg attgtcggtt cattacatgg
     2761 aatggaaatc atgaactggg tattttcgat ttatttgctg acaaacgcta tgcttactcc
     2821 gatttacgga aaacttgcgg ataaagtggg acggaaacca atctttattt ttgggacatt
     2881 attgtttatt atcggttcgt tattttgcgg tttatctcaa agcatgattg ggttgattgc
     2941 tgctcgtgcg attcaaggga tgggtgctgg ggcaatgatg ccagtagctt tgacgatcat
     3001 cggcgatctt tattctattg aaaagcgagc aaaagtttta ggtttgaata gttcagcctg
     3061 ggggattgcc agtgtttttg gaccgcttgc gggaggattc atcgttgaaa cgatcagctg
     3121 gcactggatc ttttttatca atgtgccgat cggaattcta ttaattattt tgatttggct
     3181 atatttaaat gaaccaaaaa tcatacatga gtctaaacca atggatattt ttggtagttt
     3241 tagtttgatg gccatgcttg tctcattgct gttagggttc caattattag gagacgaagg
     3301 aatgagtccg cttgtttctg ctttgctgct aggtagtatc gtaatgttag gtatttttgt
     3361 ttttgccgaa aaaagagcta aagatcctgt catcatgatg catttattca aaaatccact
     3421 atttgttgtg gtcaacttgg ctgcagcatt ggctagtggt tttttgatgg gaatcgatgt
     3481 ttatatccct atgtggatgc aaggtgtatt agggctgaat gcagcaattg gtgggctggt
     3541 attagcacca ttatcactag tctggatggt cggttctttc cttgcaagca agtggatgac
     3601 tcaaatgaaa actcattggg tcttgagaat tggactacta atcgcagcta ttgggggcgc
     3661 ttggttgtat cttatgcctt tcagaagtaa ctatttatgg ttttttgcta tatcaacggt
     3721 catcggtata ggcttaggtg tgaccatgac tacctcgact gtcagtgcac aaaatagtgt
     3781 atctcgtgac cagcttggtg tagcaacttc ttttaatacg ttagttcgaa caattggtca
     3841 aacagtcatg gtttctattt ttggtttatt gataaatggg gtaactaaac gagaacttgc
     3901 agcagcaaat ttaacaaatg atgcagatat catgaataaa ctggtgaatc cacaaacggc
     3961 taaatatatt gatgcggata ttttgttacc attaagaaaa attctttatg atgggttaca
     4021 ttccgtttat ctagttggct tgttactcgt gatcattgct ttggtcttaa cgcttttcgt
     4081 tcatgaaaaa agtggtaaaa taaaacagta gtttcggtta agatatgtac gtagccgaat
     4141 cattcaaatt taaagttatt caaaaataac ttcttactaa ggaaggcgaa aatatggcat
     4201 ttattcaagc aaatatttat tcgaatgtgt tagaaatgga agtcaatcta aatgtgatac
     4261 taccgcaaac aacaaaaaag gtgattggca ccagttcaga gcaagagaca acggatatac
     4321 ctgttttata tttacttcat ggaatgggtg gcaatcatag tgtatgggaa agacgtacgt
     4381 cgattgaacg ttatgtagca aactacggat tagctgtcat catgccatct actgatcttg
     4441 gctggtacac agatacagtt tatgacatga agtattggac attcattgca gaagagctac
     4501 ctgagatttg tcatgaatta ttcccgcaat taacaagaaa aagagaaaaa acatatgccg
     4561 ctggattatc gatgggcgga tatggcgcgt taaaactagg ccttgcaaaa tcagaaaatt
     4621 tcgcagcagt aatctctctt tcaggcgctg tttctgtagg aaatcgaatg gatgatcttt
     4681 tgatggttcg taaagcatct ttttgggaag ggatctttgg accattggat caaatcgaag
     4741 gttcaaaaaa tgatccgcaa tacttattga aagaactagt aaaaagcgga aaaccagttc
     4801 caagatttta tatggcttgt ggggaatctg attttcttta tcaggcaaat caggaaatgg
     4861 tatctgctat gcaggaacaa ggcttggcgg tcacctttga acaaggacct ggcgatcata
     4921 actggatctt ctgggaccaa tggattcaac gtgcattggc gtggctaatg gaagaaaaat
     4981 aaaaaaagag tcttaaaaag atagctccta tagagatcac aaacatagtg atctctatag
     5041 gagctttttt actgctcgtt ttctcttctt ttattttgtt ggcataagcc ttcaatatag
     5101 gtttgtgcac tcgttagaaa gagtgctttt tcattcaatt ctgcatggga ctgcatactt
     5161 tctttaaatc cctctaattg attttcaact acataattac gcataaatag aactgtttct
     5221 ttcaaaaatt catttccgtc cataattttt tgtcgaagct gctgttcatg ctgctgatcc
     5281 attaactgtc caatcaataa attgtggaga gaggcaatgg cctgatgact ttgggtgact
     5341 gaaaatcctt cacgaacaag taattggatc atttgctcca aatgttctaa tcgactcgga
     5401 aaagcgggca cagtattgat ttctaattct gccccacaag ggaaacgtgt ataaaggtca
     5461 tagtaatttt ccatatactg cagcaactgt tcattccaag gcaaagttgg atctggaagc
     5521 gctaattctt cttccattgt ttcagccatt ttttgcaaga gctgttgttt gtttttgaaa
     5581 taccaatata aagcaggtgc ttgaacatga attctgtttg cgatgtttcg catggaaagc
     5641 tgcgaaagag cttgtgtttc agccaggata tcaaaggcgg cctgaatgat gattgcttga
     5701 gaaagcttta tttccatttt atcaacctcg tgtattgcat tatcttttta aacatggtaa
     5761 attgttagtc ggtctaattt tacagtgtta aattagtcct gtcaatttaa acaaaggggt
     5821 gtaatcaacg aatgaaatta atcttacgac atgcgaaaaa atataaagta gctgttttta
     5881 tttccttgct gtccgtagca gtcatggttg cagcagcatt atggcaacct aagttactac
     5941 agcaagtatt ggaagctatt attacagaag ataatgatga aatgaaaaca attggtattt
     6001 acctgatcag tctggctttg ctaggattag ccgcaggtgt aacgaacacg attttctctg
     6061 caaaagtagc tcaaggcgta agtgcagata tccgagaaga agcatttcga aagatccaga
     6121 cattttcatt tggaaatatc gaacagttct ctgctggaaa tcttgttgtt cgtctaacaa
     6181 atgatatcac gcaaatccaa aatttagtga tgatttcttt gcaatcactt tttcgaattc
     6241 cattcttatt tattggtgcc ttcattttag ctatgatcac gatgccgcaa ttatggtgga
     6301 tcatcgtagc gcttatcgtt acggtatttc tgattacggc actttcattt acaaggatgg
     6361 gcaagcactt catgatcatt caaaaactga ttgatcgtgt gaatagcatt gcaaaagaaa
     6421 acttactagg gattcgtgta gtgaaatctt ttgtacaaga agaaaaccaa ttgaagtcat
     6481 tcagcaaagt aagtgaggac ttaacaaaac acaacatcat agtcggtaca ttattttctg
     6541 tgatgatccc gtccttcatg ctggctgcca atttggctgt ggttggggcg atcttttttg
     6601 tgagcgatct tgttaaagat gatcctacgt taattggtgg aattgcttca ttcatgaact
     6661 acttgatgca gattatgatg gcaatcatta ttggcggaat gatgatgatg atgacttcaa
     6721 gagcagccgt atcgctgaag cggattgcgg aaattttaga tgctgaacca gatcttactt
     6781 atttagacgt tccagaacaa gagttgacgg gttctgtcac ttttgaccat gtttcttttc
     6841 gttatcctgg tgaggataca gatacgctta aagatatcag cttttctatc aaacctggag
     6901 aaatggttgg tatcgtcggg gcgactggtg ccgggaagtc aacactagca caattgatcc
     6961 ctcgtctatt tgatccgaca gaaggcaaag ttgaagtagg tggtgtagat cttcgtcaag
     7021 taaatgaaaa gagtttaaga caaacggttt cctttgtttt gcaaaaagca attttattct
     7081 caggaacgat tgctcaaaac ttgcgccaag ggaaaaagaa tgcaacagaa aaagagatgg
     7141 aacatgcttc ttctattgct caagcaaaag aattcatcga aaagttatct gatcgttacg
     7201 aagcaccaat agaagaacgt agcagtaact tttctggtgg tcaaaagcaa cgtttatcca
     7261 ttactcgtgg cgttatcggt aatccaaaga tcttgatcct agatgacagt acgagtgcac
     7321 tggatgctcg ctctgaaaag ctggtccgag aagcactcga tcgagatttg aagggaacaa
     7381 cgacgattgt catcgcacaa aaaattgctt ctgttgtcaa agcagaccgc atcttagtat
     7441 tggatgaagg cagattagtc ggcgaaggaa cccatgagga attggtagct ggaaaccgtg
     7501 tctatcagga aatctttgaa actcaaaaag gaacggagga gtaagtatga ctgatctaat
     7561 aaaagcaagt aaatttttct atcactattt gaagcggtac aaactctcct ttttctttat
     7621 ctttatcaca gtgatcattg ctacctatct acaagtaaag gcacctcaat acatcgggga
     7681 agcttttcaa gaattagcta attacgtagg aggcttgatg caaggcgtag acgataaaag
     7741 caaatttgtt tctgtaatat ggaaactctt gctgttttat gtactagcta gtgcagccaa
     7801 ctttatctat agtattttgt tcacacaagt agtagggaag tcaacgaacc gaatgcgtat
     7861 cggtctattc aacaaattgg aaaaattgac gatccgtttc tttgattctc atcaagacgg
     7921 tgaaatttta agtcgtttta ccagtgactt agataatatt caaaatagtt tgaaccaagc
     7981 tttgcttcaa gtcatcacga atgctgtttt acttgtcggg atcttgatca tgatgttccg
     8041 ccaaaatgta gagttagctt gggctacaat tgcttccact ccagtagccg ttttgatagc
     8101 tgtcttgatt atccgcaaag cacggaaata tgtggatctt cagcaagatg aagtggggaa
     8161 actaaatggt tatatggatg aaaaaatcag cggacaacgt gtcatcatca caaatggctt
     8221 acaagaagaa acgattgaag gattcttaga gcataatcaa agtgttcgcg aagcaacctt
     8281 caaaggacaa gcttattctg gtctactatt tccgatgatg caaggaatgt cactggtcaa
     8341 tacagcgata gttatctttt tcggcggctg gttagcatta aatggtgatt tggaacgttc
     8401 ggtggcatta ggcttagttg tgacattcgt ccagtattca caacaatatt accaaccact
     8461 gatgcagatt tcatctggat acagcatgat ccaattagcg attacagggg caagacgatt
     8521 gaatgaaata tttgatgaaa aagatgaagt caaaccagaa aacggtaaag catttgatgg
     8581 tgttgaaaaa ggtcttgcgt tgcagcacgt agattttggt tattctccag aaaaactagt
     8641 cttgaaagat gtctcgatca atgtggacaa aggagaaatg gttgctcttg ttggtccaac
     8701 aggatcgggg aaaacgacga tcatgaatct gctaaaccgt ttttacgatg tcaatgatgg
     8761 ttcagtagtc atcgatggaa tagatatccg agattatgat cttgatgcat tacgtagaca
     8821 tgtaggaatc gttttgcaag aatctgtatt gttctccgga acgatcaaag acaatatcac
     8881 attcggcaaa ccggacgctt cagatgaaga agtcatcaat gcagcaaaac aagcgaatat
     8941 tcatgacttc atcatgacgt tagaaaaagg ttatgataca gagatatccg aagaaaataa
     9001 cttattcagt acaggtcaaa agcagttgat cagtattgct cgaacgatca tcacaaatcc
     9061 atctttattg attttggatg aagcaacaag taatgtagac acggtaacag aagcaaggat
     9121 ccaaaaagca atggatgaag caatcaaagg aagaaccagc tttgtgattg ctcaccggct
     9181 gaaaacaatc ttgaatgcag atagaatcgt tgtcttgcgt gatggggaag tcattgaaga
     9241 aggcagtcat catgagttat tagcagaaaa tggattttat gcggaacttt atcataatca
     9301 atttgtattt gaaagttaaa ttaaaagaac ctcgttataa cggggttctt tttatatatt
     9361 ttatgttgtt tgtttttata aggggca
//
LOCUS       DAFEKH010000084         8968 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.087, whole genome shotgun sequence.
ACCESSION   DAFEKH010000084
VERSION     DAFEKH010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8968)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8968)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8968
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.087"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(56..349)
                     /locus_tag="LP386_002640"
     CDS             complement(56..349)
                     /locus_tag="LP386_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HBL1919824.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(377..1042)
                     /locus_tag="LP386_002641"
     CDS             complement(377..1042)
                     /locus_tag="LP386_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HBL1919825.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(1182..1814)
                     /locus_tag="LP386_002642"
     CDS             complement(1182..1814)
                     /locus_tag="LP386_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1919826.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(1821..2888)
                     /locus_tag="LP386_002643"
     CDS             complement(1821..2888)
                     /locus_tag="LP386_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBL1919827.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(2885..3616)
                     /locus_tag="LP386_002644"
     CDS             complement(2885..3616)
                     /locus_tag="LP386_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HBL1919828.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(3785..4264)
                     /gene="greA"
                     /locus_tag="LP386_002645"
     CDS             complement(3785..4264)
                     /gene="greA"
                     /locus_tag="LP386_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HBL1919829.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(4400..5575)
                     /gene="mltG"
                     /locus_tag="LP386_002646"
     CDS             complement(4400..5575)
                     /gene="mltG"
                     /locus_tag="LP386_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HBL1919830.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            5779..6948
                     /locus_tag="LP386_002647"
     CDS             5779..6948
                     /locus_tag="LP386_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBL1919831.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            complement(7215..8849)
                     /locus_tag="LP386_002648"
     CDS             complement(7215..8849)
                     /locus_tag="LP386_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919832.1"
                     /translation="MRWYMNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAF
                     HINRALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLY
                     IVTLITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPL
                     ILLGFIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIF
                     LIIKLIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDS
                     ELLSFGIGLTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLN
                     IIQAPWRFMIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNM
                     VKEMNFQGTYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPN
                     KDEITFTLKSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTI
                     RYSYTFFSKISLFISIITLIVLLFYCIKLKIRTSHE"
BASE COUNT         2855 a         1701 c         1333 g         3079 t
ORIGIN      
        1 atattttcaa aagaaaaaag agaaggtgac aaaaattgtg tcaccctctc tttttttatt
       61 gttttttaaa gtgataggtt ggctcctcca ggttgggatc ataatcaaca agtaaatcat
      121 atcctttaaa gaaccattca tctgcttcct cgataaaaaa aagtgtccca tcaatttcca
      181 ctttctttac aggatgttct ggctgttcaa ctgacattcc aatcgaaaaa ccatcatgaa
      241 cctctgtttt gccgtagact tttccaaaaa aacgtattcc gtaagtttct ggcagatcaa
      301 tttctgagtc aaaccacttt tgtgcttttg gcgttaccgt taatttcatc ccaacaacct
      361 actttctctt ttctttctat tgattcatct tatcgtctag aatatccaca tcgcctgtct
      421 ctccaataac cagtagatta tcattttcac gaacatattc atctgctgca ggagaagcga
      481 taaccgtttg atctactctt cgtatggcga ctactgttaa gtcaaaacgt tgcctgaaat
      541 ttaattcagc taatgttttg ttgaaaaatt taggattgga gactcggatt tctgctaaag
      601 aatatttatc tgacaactct aggtaatcta aaatattctt tgacactaaa ttatgcgcaa
      661 tccttattcc catgtctcgc tcgggatgga cgacgcgatc agctccgatc ttttcaagta
      721 ctctggcatg atactcattt tgggcttttg ctaaaatatt tggtacgccc atttccttta
      781 ccatcagagt aactaagata ctggcttgaa tatcttctcc aatagcgaca attacatgat
      841 cgaaatttct tatgcctaat gatcgaagtg tcatttcatc ctgtgcattt gccacaacag
      901 catgagtggc tatattcata tattcattga cccgatcttc attactatca atagccagta
      961 cttcttgacc agcttcgatc agtgttcggc agatacttcc gccaaatcgt ccaagaccta
     1021 caattgcaaa attttgtttc accgttttcc tcctttagta tcttcttttc tcagtataac
     1081 aaagccttta caaaaacaaa agcaagcatc attattgtaa aaaagccaag aaaaataata
     1141 gttattttct cagcttttga ttatcctctt tatcatcgtt tttatttcac caaaccatgt
     1201 ttgaatgcat agatagcggc ttgtgtacgg tcttccactt ctagcttagc caatatattg
     1261 gaaacatgtg tttttactgt tttcagtgta ataaacaatt cgtccgctat ttcctgatta
     1321 ctttttcctt cagaaatcag cattaaaatt tcattttccc gattcgttag ttcttcatgt
     1381 aatacaggct catttcgccg actcattttt tccatcattt ttgttgtcac ttctggttct
     1441 aatactcgct cgccacgttg cgttgccctt atagcatcag caatttcatg tgcggtagag
     1501 gtcttcaaca aataccctgc tgcacctgct tcaatggcag gataaacttt ttcgtcatca
     1561 ataaaactgg ttacgataat gattttagct tctggccaat cttttaagat tgcttttgtt
     1621 gattcgatac catccatttc ttccatgact aagtccatta aaatgacgtc cggtcgaagt
     1681 gtcatcgcct tctcatagcc ttgtcgtcca ttttcagctt ctccaattac ttcaatgtct
     1741 tcttgaatag ataaataaga agagacgcct aagcgcacca tttcatggtc atctactaat
     1801 aaaactttta tcatccttat ctatgcctcc ttcatcaaag ggaccttgat ttctacactt
     1861 gtaccttgac ctttaaaact aatgattttt actgttccac caataccagc tactcgttct
     1921 ttgatattgt tcaatccata acttcccgtt ttcgtttcat tcatattaaa ccctgttccg
     1981 tcgtcaataa tacgtaacaa aagattattg tctattttgt gcaaatatac ctctaattca
     2041 ttggctttag catgtcttaa tgtatttgat aacaattctt gaacgattcg gaacaagtga
     2101 tcctcaatgg aactagatag ttttacatct tctacatccc atttcagcga aatctggatt
     2161 ttattttgca attccttcaa taactgctcg ataccttgct ttaaactttt ctcttctaaa
     2221 ttgactggac gtagatgaag aagcagcgca cgcatctcag actgggaagc gttgatgatc
     2281 tctgctacca ttttcaactg cttgcgaaac atttctggtg tctcgctttt ttctgcttgc
     2341 tccgtcaatg ccgacatcat catcattgct gcaaacaatt gttgcgaaac tgaatcatgc
     2401 agctcacggg ctaatcgatg tctttctaat tctaaaattt cttctttggt ttgtccatct
     2461 acatattggg gacggctcgt tacaatttgt aattcactag atacttcaat cattttttct
     2521 tttatcttag tgatttcctt atcaatatct ttgatgtata aatcgtccga tgcacttggg
     2581 atcggaagaa gcaacaattt ggattcataa ttgccagaag aaagtgcacg cagcttttct
     2641 tcgattttcc cgtattttgt cttttgaata agtgataata atagaaagac aattaatcct
     2701 acacctaagg aaatggctaa caaatggaag ataagcggaa catataataa acgtgcacgc
     2761 agtaattctc cccaccaatg actttgattg ctggcataaa aataagtgaa aagtgaaaat
     2821 agaataataa ggaaagccgc aatccccgaa taaacagcta gcatcgctct ggatattttt
     2881 cccatcatat tcgtatcacc tcgacatctc caatcaaggt attagtaata atcttcaatc
     2941 tacgagggtt ttcatcataa tcactgctgt agattttgat ttgttcattt ttcaaagaaa
     3001 attgctcttc ttcaaacaag acatttccta ctaatgtcgc atgctctaat cggatggcta
     3061 cgcccaaagg tactaagatc cgtgttctgc ctatcccttt tcttacaatc acaatattat
     3121 catcttttgg caaaagcgta ttgcccaaat ctatgatagt atcaccagaa atgacggcga
     3181 tgttgatatc gtcccattca tagacgtcgt ttccaatacg ttggttaccg aataattgct
     3241 gtcttttccg ctcattatta tgtgttttta attgctctgt ttggatcatc atgatctgtt
     3301 tctttcgcca aaaagcattt ttggttaaat ctatccctga aatctctaca cctttcagac
     3361 caataaataa aacggcaaat acagccatca tccataaagc aggactgttg actaagctaa
     3421 aaaaaatgac caaacttcct aatatcaatt gaaaattttg aaatttagta cgaggatgtt
     3481 tgcgcatagc tagatatata ttgaaaatac cgaatatcac taaaagcaaa agtccagtat
     3541 tgtttacgat ttgccaaaca gcaaataaca gcagtagtgc ttcaactacc acaaaaaaac
     3601 gccaagaact attcatcgct ctttctccct cctgacacat tctcatttca tcatacctat
     3661 ttttttaact gttggctata ggactttaga tgtaagatcg tttgttgaaa tctaaaatac
     3721 acaaagagaa aaagatctag agtgtatcat cagtaagatg aactctctag atctttcagt
     3781 cagactacgc ttgttctact ttgacgattt taactaacat atcgccacct ggagtagcaa
     3841 tagttacttc atcattttta cgtttgccaa tcaatgcttg cgcaatagga gaatcattgg
     3901 aaattttgcc agaaaacgga tctgcttcag cgcttccgac aatcgtgtac tcttcttctt
     3961 ctccatctgg tagttcgatg aatgtaactg ttttaccaat tgatacctca tctgcatcta
     4021 caccgtcgtt atcgatgatt tgagcaaaac gaatcatatt ttcaattgtt gtgattcttc
     4081 cttcaacaaa tgcttgttca tctttcgctg attcatattc agagttttcg gaaagatctc
     4141 cgaaaccgcg ggcaattttg attcgttcaa tgatttctcc gcgtttgact gtttttagtt
     4201 cttctaattc tttttctaat ttttctttac cttctagagt cattggataa actttctcta
     4261 ccatgtgtaa cgtctccttt tttcgataaa ataccgcaaa aggtaatctt ttgaggaata
     4321 tagtccaaaa aagattacca cgcttttctt caaatgtaaa tgtttttcta aaaatgatca
     4381 atgtctagag cctgtttttc taagaattat ttacatattt ttccactaat tccatatgtt
     4441 cttcataagt tttagcgaaa taaacatttc cagtgctcgt atctgctacg aaataataat
     4501 agtcattttc tgctggttct aatactgcct tgattgcctc ttcgcttgga ttgtcaaaag
     4561 gtccaggtcc atagccggta ttggtataca aattatatgg tgaatctaca gctgtatctt
     4621 catacgtcac taattctttg tgttcaccta atgcgtataa aacagagata tctgactgaa
     4681 gtggcatatt tgctttgatt cggttaaaga agacttgtgc aatgttttta cgatcatttt
     4741 cttttacgcc ttctttttca actagagaag ctagagttaa aacttcttgt acagtcaaat
     4801 ttttctgctt gatagctgaa taatagtttt gcatgaccgt attcgtcttg ttcaccattt
     4861 caatcactag atccttaagc gaagtactcg tgtaataatc atatgtggct gggaataagt
     4921 aaccttccaa acggtatttt gtgttctcag ctttagatgc actttccaac agttctggga
     4981 atttttggtg caactcgtta aagaaagtct catcattcac taaatctaaa aattctttct
     5041 tgtctttacc agttaccttc gctacccgtt cagcaatctg atcgatatcg tacccttctg
     5101 gaatggcaat tttcccatct gcaacttttg ttggctcaga agtaccgcct tcttgcaact
     5161 gtttgccaat ctcgtcaaga gtcatattag gcgctaactg ataatagcca gcttgaaagc
     5221 cagttaaatt tttaaatttt gtataataat tgaaaacaat cccgctttta ataatattgt
     5281 ccttctccaa aatctcacca atctgcttgt tagaagagcc actcgggatc tcgacttgga
     5341 ctaattggtc atctgattta tctaaaggct tcaacccgct atctacataa cgatacacgg
     5401 taaatccaag aaatccgcca ataatcaata atgtaagagc aatcactaaa atgatcttcc
     5461 tcacaatctt atcttctttt ttacgcagat ttctccgctt gtcgattata tctgctgtag
     5521 ctgccttact ggcttctttt ttatctttac ttgggtgttg tttgtttcct gacaaaacaa
     5581 ctcctcctta ctatcaagtt cgtaacttta ttcattatac atgatatttg aattggcgtg
     5641 aatgatttta tttaaatatt ctatcaaaaa tgtaagtagt aaatccatta ctataagatt
     5701 aaaataaatg ttatcaagat acaagctatt ttagctttat tctttctgta aaaaagaaag
     5761 gagactaaat aaactattat gaaaaaagga aaacatgcta aaaaaagaaa atattcattt
     5821 ttaatgatcg ttgtcgtgtt gtttagcctt agtgcgttct ctacaggaac tattcttgga
     5881 tggcaatttt acaataatga acactctcag atagttgccc atgctcaatc agctcaaaaa
     5941 aagttgatac tgactaccaa tgaacaacag ctcgttgaaa aaatcgatca actattaaga
     6001 aaaaatgatt atattggctc aatttacgta aagaaaaata atcgcatcat catggaaaaa
     6061 ggctatggct atgcgaataa actcacgcaa caaccaaatg atccttctct ttattatcag
     6121 attggttcgg ttcaaaaagc attgactact cttttgattt taaaacaagt cgagcgtggg
     6181 cacctttctt tagatactaa gctggctcaa ttctatccac aaattgctgg cagccagcaa
     6241 attactatcc gtgacttgct gtatatgcgc tcaggcttgc accgaactgc ttctccaacc
     6301 ataccgatga ctgatgaaga agtcgttcaa tttgcgattc agcacttaaa atttacagat
     6361 tatcagacct ctcattatga ttcattgaac tttaccatat tgactggaat tttgatcaaa
     6421 ttaacaaatc aaccgtatga aaaattattg accgatgata tcatcgaacc tttaggatta
     6481 cagcatacaa aattttatga ccaagtcaaa aattcatcca atcatgcact atcctatcaa
     6541 atgtctaaag aggatgatta ctttaaacca ctgacagaat ctgaaacaga gatccataac
     6601 gaattaggga ctggtaatat cagtatgtcc gtctatgatt taaatacgct gtttacacaa
     6661 gttttatctg gaaaactagt ttccaaagac ttactcttct cattatggcg tgaaaatgcg
     6721 aatggacatc catatagtgg tggggtatat agcggagata attatatcct gtcgcaagga
     6781 aatatcgact cttttgatac atctgctata tttagcaaag attcacagga tgctatcatc
     6841 atggaaagca atataaaagc tgacaaaact atcaaactgc ctactgctga tctaagaaac
     6901 caaatctatg acctgatgga aggaactact aagttggcaa atagctgata tgatgaaaag
     6961 atagcaaata ctacttcttt gaatagcatt tgcttaaaaa aagtactcga ctaaacgtag
     7021 gaaagagtgt gggacaaatc taaaaatcaa tttttgctac agactttaat tccaaataaa
     7081 cagaacagaa agaggtgttc ttctttctgt tctgtccaaa ttattctaag atttctcttt
     7141 accaacatta tttgacaaag ggcctattaa atctaaaata gtatctttag attgctaaaa
     7201 tatgtgctag caaatcattc atggcttgtt cttattttta attttatgca ataaaaaaga
     7261 agaacaatta gcgtgattat agaaataaat aatgagattt tagaaaaaaa tgtgtatgaa
     7321 tacctgattg ttactttatt tattccactt tcacttttta ctgtaacaaa aggacctcct
     7381 tgttttagta ctgtagcatt ttttgaatta acagtaaccg ttaatccttt ataccggaat
     7441 acaggtaaaa ctattgtttt gccttttgaa gatttaagcg taaatgtaat ttcatcttta
     7501 tttggagaaa agctactata aataacttga ccatcttctg taacttgatg gtttttcaaa
     7561 agcaattgat cttttttata gcctataggt acataatcaa aattctcaaa ttcttcaagt
     7621 ttattttcca tttgttcatt agaataagtt ccttgaaaat tcatttcttt caccatgtta
     7681 actactgatg aataatttaa aattgaaata gctaatatta ataatagtat aaaatttctt
     7741 ctccttgtat aagaaaattt ttccaactgt ggagaaataa atagagatac tgaaaaagat
     7801 atgaacaatg ttgaaaatat cataaaacgc caaggagctt gaataatatt taaaggagta
     7861 ttttgtaagg caaaccatgg aaatattttt gtacaaagta gaatagatat tatacccatt
     7921 atataagtga ttttagataa gattcctaat tttttaaagt taaatgttag tataattaaa
     7981 caaataagca aagttaagcc aataccaaat gatagtaatt ctgaatctat acttccaatc
     8041 aaaaactctt tacccagata aattgctctt ttttgtaata tatccacata aggtctattc
     8101 agatcttgat acaatgtctg ctcaatcata ggacctataa acgctagtga aagaagtaaa
     8161 gtaactatag cagcttttat taatttaata attaagaaga tttctatttt ctttttccga
     8221 taaaattgaa taattaaagc aattataatc attaccatag tcatagctac agaaagaaca
     8281 tgagtgtaaa ttaataaagt catgctaatc gccaacataa cccaagattc tttttttgag
     8341 tcgtaaagct ttataaaccc gagtaaaata agaggaagta ttgacattgc gagtaattcc
     8401 cccattgccc ctcgaagaaa tatttctaca ctcctaaaag aagatgttgt atatataata
     8461 gcgaaaaagg agctagtaac atgttttttg gtaatttcat acattacata atgacatata
     8521 aatagagtaa tgagcgtaac aatataaaga aaaaggttat agcctattgc taaattagta
     8581 aacttgatca ataaaaataa aggatataga gttaaccatg ggtaaaaatt atttacttgc
     8641 atgccatatg atctaaacgt ttcaaaatta ataggggagc taaaaataga ttctaaactt
     8701 aacgcacgat taatgtgaaa tgccgtatca taaaagccaa atatttccat gtttttaaat
     8761 gctggaaata aatataataa actaacaaat gcataaacta taaatatttt tacagaaaaa
     8821 atttttttca aattcatata ccacctcatg tttttttata ttacatatag tatcatttat
     8881 ttttttaaaa cactagatta gtcactatat aaaatgtgat taattttatt attaataaaa
     8941 tattttttat attacaaaag tagtgttt
//
LOCUS       DAFEKH010000085         8693 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.088, whole genome shotgun sequence.
ACCESSION   DAFEKH010000085
VERSION     DAFEKH010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8693
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.088"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..400
                     /locus_tag="LP386_002649"
     CDS             <1..400
                     /locus_tag="LP386_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HBL1919833.1"
                     /translation="ADGLTLDIWLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSI
                     TSAFKKLKEYGFYQGTEHRTIKYLNNLIEQDHRPVKRRNKLYRSLRTASTTIKGMEAI
                     RGLYKKTRKEGTLFGFSVCTEIKVLLGIPA"
     gene            complement(1016..2056)
                     /locus_tag="LP386_002650"
     CDS             complement(1016..2056)
                     /locus_tag="LP386_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBL1919834.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(2405..2731)
                     /locus_tag="LP386_002651"
     CDS             complement(2405..2731)
                     /locus_tag="LP386_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919835.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(2718..3521)
                     /locus_tag="LP386_002652"
     CDS             complement(2718..3521)
                     /locus_tag="LP386_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBL1919836.1"
                     /translation="MGDILMARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVD
                     IDPQGNATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAERE
                     FTQVGSEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLK
                     GLIKLSETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKT
                     YIRRTITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(3874..4164)
                     /locus_tag="LP386_002653"
     CDS             complement(3874..4164)
                     /locus_tag="LP386_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HBL1919837.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(4300..4479)
                     /locus_tag="LP386_002654"
     CDS             complement(4300..4479)
                     /locus_tag="LP386_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919838.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            complement(4476..4826)
                     /locus_tag="LP386_002655"
     CDS             complement(4476..4826)
                     /locus_tag="LP386_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919839.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(4819..6144)
                     /locus_tag="LP386_002656"
     CDS             complement(4819..6144)
                     /locus_tag="LP386_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBL1919840.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRS
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTKSLNLFTTEETRSQRRKKLAQMIQERIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFIAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGILSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
     gene            complement(6313..6897)
                     /locus_tag="LP386_002657"
     CDS             complement(6313..6897)
                     /locus_tag="LP386_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1919841.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
     gene            complement(7108..7311)
                     /locus_tag="LP386_002658"
     CDS             complement(7108..7311)
                     /locus_tag="LP386_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919842.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            complement(7321..7743)
                     /locus_tag="LP386_002659"
     CDS             complement(7321..7743)
                     /locus_tag="LP386_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919843.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            8057..8671
                     /locus_tag="LP386_002660"
     CDS             8057..8671
                     /locus_tag="LP386_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1919844.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIITSVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
BASE COUNT         2698 a         1573 c         1318 g         3104 t
ORIGIN      
        1 tgcagatggt ttaaccttgg atatttggtt acgtaaaaaa cgggacacac aagcagccta
       61 tgcttttctt aagcggttag tgaagcagtt tgatgaaccg aaggttgtag tcacagataa
      121 agccccctct attacaagtg cctttaagaa actaaaagaa tacggctttt atcaagggac
      181 agaacatcgt accattaaat acctgaataa tttgattgaa caagaccatc gtccagtaaa
      241 gagacgcaat aaattatatc gaagtttacg cactgcctct accacgatta aaggcatgga
      301 agccattcga ggattatata agaaaacccg aaaagaaggc actctcttcg ggttttcggt
      361 ctgtactgaa atcaaggtat tattgggaat cccagcttaa atcatagata ccgtaaggga
      421 ttttattctt tatttaaaac tttgcaacag aaccgtccgt tgcgggtaat accgtaacac
      481 tgaagggcac gcattaaggc gtcatcttaa tgctttcctg taggacactg acggagatta
      541 ccagtctccc gagccttaca ggggcctttc ttttttttgt attttcaatt atcacaattt
      601 atcgtccaaa agtgcagaac gaaaatcaat tcatcacaag catatcagac aattaaattt
      661 aaaacaacta aaaatataca aaaaagtgta attgaatatt agcagcactg cctgaaaaga
      721 agtaatatca ggcttttcag cttggggaaa taagtgaatt acctctcttc atgaattatt
      781 ataactcaaa aaagcacata tgcaaacact agttccctat ttttttgaat gaaaaataac
      841 taaaatatct aacgattatg actttaaaac ctacgtttgt gattgttttc ataaactttt
      901 aatctaaaaa ctccggaata atagctattt atttgtaaca tttgtaataa aattaaaatc
      961 ataaaaaagt tctaatttaa aattgatcat ttttatagtg atcgcttttt atcaactact
     1021 ctagccaatt ttccgtacta actgttggta attcgttaaa tgtttctctt tgttcgtttg
     1081 caagctttgc cgcaatagct ttttcgacaa accaattttt tacataaacg aaaattagat
     1141 tctgcaaatt gtttactttt tcagtttttt gtttttgata agctttcagc aaagtcatat
     1201 ataatccttt gtcagcatca attccataag attccagttc ttcataaaca acaactgttt
     1261 gctctaattc ttcagctttt ttctttgcat tatgaatagt ttggacggtt ttttgagcgt
     1321 cttcgtaagt actagaaaat gtttttatca agtttaatac attttctggt acaaatgtat
     1381 ttatactgtc ctctttcatg atgtcgacga agttatctag taaaacttga ttttgtaact
     1441 gatcagtttc agtgtctatt atgtgtctat tagtgtctat agaattagaa tagaatagat
     1501 tgtctgcgat tttcgcaatt acggttgagt ccttgatatg actggatttt gccgtatttg
     1561 cgattttcgc aattacggtg gtatcattga tttctcgcgg ttttgccgta tttgcgattt
     1621 tcgcaattac ggtggtatca gtattgtctt cctcttccat gattttaaag acgtcttgat
     1681 tcgttacttc tggcttgcct aagtacaata aattaggcat ggattcaatc ttaccgtcac
     1741 gtttatttac tcttcctctc ttctgtttca gaagacctgc tttttctaat tcctttttga
     1801 ttttagatac tttaccttcg cggcattgta acaatttcat taattcttca actgtgaata
     1861 tgaaaaatat attatcatca gaatctaccc agttattttt gactgaataa tcaaatcgat
     1921 ctttaagtag catataagca atttttgcat catttgatag atccatgtat ttttcgttag
     1981 taaaaaatac cttaggcatt tgataatatt tttcacgata aatttctttt gatttgtaat
     2041 aattaaaatc attcatagcc aatcctcttt ctgtaggata gcgttttgtt caaaactatg
     2101 ttacaatgaa ttaaacaaat atatctatcc actatatatt tttctactgc tgataagtcg
     2161 ccaaactttg ttaaagcagt agtctttttt tatctttttt tagtttacct taaaaaataa
     2221 attaaagcaa accgctctat ttcaaggttt aagctcatag taactatatc acgatattac
     2281 aataatatta tatcacgata tcgtaatatt acaatatgaa gataagcgac ttatcagctt
     2341 tgatactact gatttttata aaaaaaatat cacgatatta tgatatcgtg atattgaatg
     2401 taaattaaat tttattttgt ttctttgcta gtttatatcc ttcaatcaag tattcttcag
     2461 gtatggactt taatagcgca tcttctataa cgtctggttt acttttgtct gattcagcaa
     2521 tagtcgtcca atatttgagt gctgacatta gaattggatt tatacgaatg ctatctgctg
     2581 ttcttacact acttccttga tcttttatga ctttacttat atttttcttg gttaattcga
     2641 tttcttctac ttcttttgat ttaaaattct ttttattttt atttcctagt aatctactta
     2701 ctgcagcttg actgcgatta tcttctgcca tcaaaatcac caacttcttt taaatattct
     2761 tctgtaaatg ctttatagtc atcttcagct gttgagggtt tattaaaatt gattagatct
     2821 gatccagcag cttgcgcttc gtcaacggtt attgtcctac gaatataagt tttgaaaatt
     2881 tttgcaccaa tgactctaga aatttcggtt gctgcagacg tcatttcttt agaaatgtta
     2941 taacgcttat tatacttagt aaatagaact cctcgtactt caagcttgtc gttcgtatat
     3001 tcttttaccg tttcaatagt ttcacttaac tttattagtc cttttaatga gaaatacgca
     3061 gcttcaactg gaatgataat ttcatcagaa acagtaaatg cgttgactgt aagcattcct
     3121 aaacttggtg gacaatcaat tataatataa tcatagttgt ccttgattgg ttgaagtact
     3181 cttttaagcc tgtgttcact tcctacttga gtaaattccc tctctgcaga agaaagggct
     3241 atgtcggctg gcaaaacatc aattccttta tagtccagaa tagcatctgt aatgtcagcc
     3301 tcccctttta atacttcata aattgtaggt tggtttgttc catctatatc gaaacctaca
     3361 ttatctgtag catttccctg aggatcaatg tccactaaaa gtacattttt accgtaaaca
     3421 aatttcaaac atgctgctaa attaacgcta gtcgtagttt tagaaactcc acctttttga
     3481 ttggctactg acaatattct tgccattaaa atatccccca ttcatcttat attataatat
     3541 aattatatca taatattgtg atattgcaat atcgtatatg cattatattg taatattgtg
     3601 tgattatttt gttttaaaga tatatatcgg ttcggatata aagattattc atatgttatt
     3661 cgaaattaaa ataatcactt tttattactt taaaattttt tattaatgat aagaaatatg
     3721 ttttgcgagc agcaactaga ataatttaaa cattactaaa ctgtctatat tgttactaat
     3781 aattcccttc ttatagtgca ttttcttaga aaaaaacaat attacgatat catgatatta
     3841 agatatcgta atattataca attgtgattg atattatata tgttttttta tttttttatc
     3901 atgtttaatc ttgaaggaat catattcttt ttctaaagac aggagctttt cataaacatc
     3961 agacatgttt aaactagagg ccaggcttaa atcataaacg aatgaagcag gtaatgattt
     4021 tattctacgt tgtcgggtta tccagcttgc aaccgttcct tgtgggtagg catataactc
     4081 acaaaattgt tctacagtga ttcctaaatt cttgataatg taaacattga tcgggtgcga
     4141 gtaaacaaat gtattgatag acatggtgcg taagcctact ttcttttatt attgcgtttg
     4201 caataatagt ttaacacacg cattattcta gtatctactc ctatttgtaa aaacaaaaaa
     4261 ggattcatag agataactct atagaatccg taaaatacct tatatatata acgggaagat
     4321 ataaaaccta aaattatgat aacctgctgc agcttctaca tagaaagaga agcgctcaac
     4381 accaacctca tttatcaaac gttggccata accccaaatc tcttctgata gctgatcaaa
     4441 ggttatatac tttagctcat attgctggat aatgttcatt ctaatcgact ccatttatta
     4501 tcctggtaaa attcgatatg acgtatttcg tcgtagtgaa ttttgtcttt tccaacgtag
     4561 atccccagct catcactacc taagatcttg ccaatgatat cttctggata gtatccttca
     4621 gcgtttcgtt cttctttttg aatagatact gatctatttt ttatgactgc agcgttcaat
     4681 acttccgcaa tctcttcagt cgtcatttgt tcttttgcta aattttgact ggttcgttgt
     4741 tcattgtcgg catcaatttc ttcagtatga tcagataaat aaaaccctgc ccactttaaa
     4801 cgtccacgat cattgtaatc aatcattttt aattccccca tttccgcccg catgaccacc
     4861 aacaagtgtg cttctagtaa tgcttctagc gccttctaac attgaagaag catgtacaat
     4921 cgacgtaaaa ccatattttt gccgaatctt gtcaataatt ttatctaaat tttcttcgtc
     4981 aatttgcttt tgtggatcac taaataaatc cagctgaagc gaatcggtgt acacaagctt
     5041 gctataggtt attccaacat gccttacttc ttgtccttca taatacttat caaacaagaa
     5101 aagacaataa ttctgcaatt cctttgtatt atctgtgata gggatcttca tctggtgtga
     5161 aaaccctggt ctcgtttcta agatcgacgt gccaatgtgt aaatggacac aacctgtttt
     5221 acagttatgc tgcctaatgc gtatcgctac ttgttccgcc atttctttta ccaccagctc
     5281 gatttcattt cttctagtat aatctcgtgg taacacttgt gaatttccat atgatttttc
     5341 ctttgtcggt tctggtggga ttgctatatc tgttcgatcg atcccattag catggaagta
     5401 cagctgtaat ccaatcacac ctaatctatt cttaatcgta taaggattcc agttagcaag
     5461 gtctctaatg ctcaaaattc ccatttggtt gagccttttt ttcattcgcg aaccaattcc
     5521 ccaaaagtcc gtcatttcgg gaatattcca tactttctca ggaacgtttt cgtacgtcca
     5581 ttccgcaata aatccttcat tatgctttgc ttcattgtct aaggctaatt tagccaaaag
     5641 gggattatcg ccgacgccta ccgtagcaat caaacctaac tcttctttaa tacgttcttg
     5701 gatcatttga gcgagcttct tccttcgctg acttcgtgtt tcttcagtcg taaaaagatt
     5761 cagtgatttt gtcactttta aaatcgattc atcgatcgag taaatcagta gatcttcatc
     5821 agccacatat cttctgaaaa tattatttac ctgcatattt cgcttgatat ataggttcat
     5881 acgtggtgga acaacgtgta gtgttttagg aaatggttgt ggtaagtcac gtggtctact
     5941 cacatttgta ataccatacc gcttttttgc ttcaggagaa gaagctaata tcaatcctga
     6001 accagtatta tcagatcgac tcataacaac aagttctgtt gttaatggat ctaaatttct
     6061 ttctatacat tcgacacttg cgtaaaagct tttcatatcg attaaaaagt aatcatttac
     6121 tggctctttt gaataatcca tcataaataa cactccattc ttccacatta tacaaacata
     6181 tgttcgatgt tgtaaagaag aaatagctaa atatttgaga ataagttatc agtagacact
     6241 tacaaaaaat tctcatacta ttgtcacttt tctagataaa tggcaaaaat tttcagcatt
     6301 aaatgacaaa aactaatgag aatttgtctt tccatttttc tcctccattt ttgccaaata
     6361 acgataaatg gtggttcttg agacgttcca ccgttccgca atagtcttaa taggtgtacc
     6421 gctatccact aaagtcttca gtaattccaa atcttgttca gacaattttt caggacgacc
     6481 accaaaccgt cctcttgcac gagcagctgc tcgtcctgct gcggatcgtt ccaggatcaa
     6541 attacgctca aattctgcaa atgccgcaaa caaatgaaac atgagctgtc ctgtagaact
     6601 tgatttgtcc atcgtaatat tttcttgaat actatgaaaa ctcacaccac gctcattcag
     6661 tcgattgacg attgaaatca aatcttccat atttctacct aaacgatcta agcgccaaac
     6721 gacaagtgta tcgccagagc gaacaaaatc aatggccatt tctaatcctg gtcgattact
     6781 ttttgcccca ctcatatgat cagtaaaaat tttttcacaa ccaaatttat ttaggctgtc
     6841 ttcttgtaaa tccaaatttt gtaaaccagt agatacccgg gcgtatccta ttttcaaaaa
     6901 aatcactcct tcattaattt tattgtaaca taactttatc catatagttt aactgaacat
     6961 agatattgtt atgggtttat gaacatgaaa tgaattgttt ttttgaaaaa taaagcaaaa
     7021 aaagaaagtg tccagaaatg ggtgatttta tgaacacttt caattagaaa aaaagaatgt
     7081 cgactagaca ctcttttttt aaaatcatta tttttctttt tgatatgttt tttggtctct
     7141 tttttttctt ttttcttcag aatcttctag attagaaatt gatttttgaa ttttttgtgt
     7201 ctcctgtaaa gttcgctgaa cttgtaaagc tgattcttct ttcggtaaat taattttact
     7261 tagaatatcg ctatcttgat aaaaatttgg tgtgttcaca aattctggca taaaaaatcc
     7321 ctactttcta gttaaggttc ctgaataagt cgcaatccaa ttgtttccag ctgatttata
     7381 actttgtaaa tacaattttc catagtacca ataaccattt cttttttctt tccaattccg
     7441 tgattgagga ggtctagaag gccaaccaac tttatcaaaa atcatcgttc ctgtcactcg
     7501 tatcgtttta gaagctgctc gagcaagtaa tggagaaact attaaataat tttcagtaac
     7561 agttaagtcg ttagttgggt taccaatggc tattccgttc ctatctaaag gagttaattc
     7621 ttggttatta tctactacag tagttggttc atttgtacta tcagcaaatg taggaattgt
     7681 agttccagtt acactaattc caatagttaa aatacctaaa gataaaataa acttattttt
     7741 cattgtctat cacctcgaaa tcaaaaataa gaaaacgttt tcttaataaa tcttaacaga
     7801 taaatcaagt tatatactag aaaattcata aaatatattt ttaatgtcat aatcgtttaa
     7861 attttcttga ttgacattta tttacaaaaa atattgccat ttaaaaagaa aagtgacaca
     7921 tactatttcc tccatcatta gtttttgtct atataaggtt taccctaaat agacactggt
     7981 ataacattga aaaatatggc ttcctcgtgt atgattaggg tgtattttaa atagttgcag
     8041 aaagtaggta aaagttttga gagttgcata catacgtgtc tcatcgatcg atcaaaatga
     8101 acaacgccag attgaagaaa tgaaaaaatt cggtgcagag agaattttca tcgagaaaca
     8161 atctggcgca acgattactc atcgacctgt tttccaagaa gcattagatt acgtccgaga
     8221 tcaagatatt tttattgtgg aagctattga tcgacttgga agaaattatg acgagatcat
     8281 cacttcagtc aattacttga agaagaaaaa tgtgaagctg atcattacta gtttaccgat
     8341 catggctgaa gcaattggca atcctctcct ggataaattc attaaggatc tgatcatcca
     8401 aattttggcc atgatcgctg aacaagaacg gactgaatcg aaacgtcgcc aggcacaagg
     8461 aattaagatc gcaaaagcaa acggcgtcta caaagggcgg cccaaattat acagtgcaga
     8521 cgcaaaagat ccccaacgtc gccttgttta caaaagcatc gttgaagatc ttaaaaatgg
     8581 tgttgcgatt gctaagattg ctaaagacta caatgttacg agacaaaccg tgtatagaat
     8641 aaaaaaagac agcatggtca atgacaaata gttgatcatg ctgcttttat tat
//
LOCUS       DAFEKH010000086         8660 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.089, whole genome shotgun sequence.
ACCESSION   DAFEKH010000086
VERSION     DAFEKH010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8660
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.089"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(178..735)
                     /gene="frr"
                     /locus_tag="LP386_002661"
     CDS             complement(178..735)
                     /gene="frr"
                     /locus_tag="LP386_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HBL1919845.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(738..1460)
                     /locus_tag="LP386_002662"
     CDS             complement(738..1460)
                     /locus_tag="LP386_002662"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HBL1919846.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(1596..2477)
                     /locus_tag="LP386_002663"
     CDS             complement(1596..2477)
                     /locus_tag="LP386_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HBL1919847.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(2576..3358)
                     /gene="rpsB"
                     /locus_tag="LP386_002664"
     CDS             complement(2576..3358)
                     /gene="rpsB"
                     /locus_tag="LP386_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HBL1919848.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            3717..4196
                     /locus_tag="LP386_002665"
     CDS             3717..4196
                     /locus_tag="LP386_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HBL1919849.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            4413..5504
                     /gene="phnW"
                     /locus_tag="LP386_002666"
     CDS             4413..5504
                     /gene="phnW"
                     /locus_tag="LP386_002666"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HBL1919850.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            5497..5625
                     /locus_tag="LP386_002667"
     CDS             5497..5625
                     /locus_tag="LP386_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBL1919851.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGTQLTDKEIR"
     gene            5629..6174
                     /locus_tag="LP386_002668"
     CDS             5629..6174
                     /locus_tag="LP386_002668"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBL1919852.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(6628..8319)
                     /locus_tag="LP386_002669"
     CDS             complement(6628..8319)
                     /locus_tag="LP386_002669"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HBL1919853.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
BASE COUNT         2409 a         1772 c         1568 g         2911 t
ORIGIN      
        1 ttaaaagatt cccactatct taagtattat agcaatatct aactgttttt cctatgaaat
       61 cattgttttt ttatttaaaa actgaataat tttttctttt tttaattttt aaataaaaga
      121 aatataaata aaaacagagg aagcggaatg atccgcccct ctgtttttat gattttatta
      181 aacttccaat aattcttttt ctttatcagc agcgatctta tctacttctt tgatgctgtt
      241 atctgtcaat gtttgtacgt ctttttctaa tccgcgcaaa tcatcttcgg taatatcacc
      301 atttttttgt tgttttttat attcatcgat cgcatcacga cggatgttac gaatcgcgat
      361 ttttgcattt tctgcttctt ttttcacatc tttagctaat tcttttctgc gttcttctgt
      421 cagttgcggg ataactaagc gaatgacatt tccatcattg gttggactga ttccgatatc
      481 acttgccata atagcttttt caacatcttg aagaatgctc ttgtcaaaag gtgtgatcat
      541 taaaacacgt gcttctggaa tttggattga tgccatttgg ttcaatggtg ttggcgcacc
      601 gtagtagttc acagtaatac ggtccaaaag gctagcgttc gcacggcctg cgcggatttg
      661 cccaagttca cgttgaagat tttgtgctgc ttttttcatt ttttcttttg cttctgtcat
      721 aattgcatct gccattttta tttccccctt acagttgttc cgatattttc gcctaagatt
      781 gcacggcgaa tatttccgtg ttcatttaaa ttgaagacaa gcagtggaat atcattatcc
      841 atgcttagtg aacttgcagt tgaatccatg acttgtaatc ctttggcaat aacttccaga
      901 tgagtcagtt cttcaaattt tactgcattt gcatctactt tcggatcagc agaataaaca
      961 ccgtctacat tgtttttagc catcaggata acatctgcgc cgatttctgc cgcgcgtaat
     1021 gctgctgttg tgtctgtcga gaagtacggg ttgccggtac cgcctgcaaa gataacgatc
     1081 cgtccttttt ctaaatgacg ttctgcttta cggcgaatat atggctctgc gatttgacgc
     1141 atttcaatcg aagtttgcac gcgtgtcggt acacccacgt tttccaacgt atcctgtaaa
     1201 gctaaggcat tcataactgt agctaacata cccatgtaat cagcttgagc acgttccatg
     1261 cccatttgtg ctccgatttg tccgcgccag atatttccgc cgcccacaac gattgccatt
     1321 tcaacgccca gctcgtgaac ttctttgatt tcttggatga tttctttgat tactggtggt
     1381 ttgattccaa atcctgcgtc cccagctaaa gcttctccac tcaattttaa gactacacgc
     1441 tgatatttcg gtgtgaccat gttcattcct ccaatatttt ctattgccat tttaccatac
     1501 ttagatgatt tcgacactct aagactggtt tttcttgttt tgcttaaaaa aagggagcgc
     1561 acaaaccgtg cgttcccgtc tgttattcaa cagaattatt ttttcacttg gctcataact
     1621 tcttctacaa agttatcttc gcgtttttcg ataccttcgc caacttcgaa acgtacgaat
     1681 gttttaacag ttgcgccttt tgatgcaacg tatttttcaa cagtcatatc aggatcttta
     1741 acgaatggtt ggtccaccaa agcgatttct gctttgaatt tcttcaagcg tccttctacc
     1801 attttttcaa cgatattcgc tggtttgcct tcgttcaatg cttgttctgt aagaacagtt
     1861 ttttcatgtt ctaattcagc ttctggaatt tgtgattcgt ttacataacg aggattgata
     1921 gctgctacgt gcatagctac gtctcttgca actgtttcgt cagttgttcc atctagaaca
     1981 gtcaatacgg caatacgtcc gcccatatgc aagtatccac caaatgcagc attgtcgtct
     2041 ttttctacaa cttcaaagcg acggaagctg attttttctc cgataacttg agttgcttcg
     2101 atcaagtcag attcaattgt acctttatct gttttgattt tcattgcagc ttccatgtct
     2161 gctggtttgt tttcagcaac aagttctgca atttctttta ctaaatcttg gaacatttcg
     2221 tttttagaaa caaagtctgt ttctgagttt acttcaacga ttgctgcagt gttacctttc
     2281 acagcaactg aagccaatcc ttcagctgca atgcggtcat ttttcttcgc agcctttgcc
     2341 attccttttt cacgtaaaag atcaactgct ttttccatgt cgccttctac ttcaactaat
     2401 gcttttttcg catccatcat tcctacgcca gtcatttcgc gtagttcttt taccatttta
     2461 gctgtaacgt ctgccatgtt taactcctcc tgtgtgtttt tctttttaaa aaaagctgct
     2521 tcaaaggaga gtgaggcttg tcgcccagcc tttgaaacag ctccatcatt caaaattatt
     2581 ctgctgaaga attgtcgcct tcaacaacat ctacgatttc ttcgattgat gttgctgtgt
     2641 tttcttctgt gaaatcttct tcaactactt gatcttcacc ttggtttcct tcgatgaaag
     2701 catcagccat ttttgaagta atcaatttaa cggcacgaat tgcatcgtcg tttgaaggga
     2761 ttactacgtc gatttcatct ggatcgcagt ttgtatcaac catagctacg attgggatat
     2821 ttaatttgtg tgcttcttga acagcaatac gttctttacg tgggtcaacg atgtacatta
     2881 catctgggat tcttggcata tcagcgatac cgcctaagaa tttttcaaga cgttcacgtt
     2941 ctttgttcaa accagcaact tcttttttag gtagaacttc aaaagttcca tcttcttcca
     3001 ttgcattgat ttgtttcaaa cggctgatac gtttttggat agtatcccag tttgtcaatg
     3061 ttccgcctaa ccaacgatgg ttaacgaagt attgtcctgc acgagttgct tcttctttga
     3121 ttgcttcttg tgcttgtttt tttgtaccta cgaataatgc tacgccgcct tcttcagcaa
     3181 cgctcttcat gtaatcataa gctgcatcta ctaatttaac tgttttttgc aagtcaatga
     3241 tgtagattcc gtttctttct gtgaagatat atttcttcat ttttggattc cagcgacgag
     3301 tttggtgacc aaagtgtacg ccggcttcta gtaattgttt catagaaatt actgccatgt
     3361 ttgtttcctc cgatttggtt ttatttttcc tcttcttatc ttctaccttg ccggcaaact
     3421 ttttcaagca cctaccgaca atccaataag aatgtggatt tgctgatgca taaagcaccc
     3481 tcagctatta tacagacaaa agatccgtat cgcaagagca aatatacttt tctgctcaac
     3541 attcaatagt ttacctgaaa gataaaaaga attcaagaaa aacagtagat ttctctttgt
     3601 ttctttatta tcctttttcc ataaaataat tttaggtata aaagacgaat attattgggc
     3661 aatccttctt ttttttgtta tgatacatgt gaaatctttc gtaaaggaga aagaaaatgc
     3721 gcaaagctca aagacatttg ctgattaaac aagtcattga agaattcccg atccgtacgc
     3781 aagaagaact attaaacaaa cttgggcatt atggcgttac cgccacgcag gcaacgattt
     3841 ctcgagatat ccgtgatcta aaaatcgtga aggcacctga tgaaaatggc gtttcccgct
     3901 tcgtattgtt tcgcgaaaaa ggaactcctg agactaggac tgaggaagag gatcggctgg
     3961 ttcaaatgat tgaagacatt gtattgaaag tcgaacgagt ccactttttg acgatcgtca
     4021 ataccttgcc agacaatgct catttatttg catctgtttt agatgagatc aaacctccct
     4081 ctattgtcag tacaattgct ggattcgata cgatcatggt catctcggaa aatgaggagg
     4141 acgcaaaacg agtagaagaa tttcttcacc atccaactga agtatcactt ttttaatcag
     4201 agcacgtatt cctaatatgg aatgcgtgtt tttttatttt caatattttc cttattgaat
     4261 aaacctttac actctttaca aaaatacatc attttttatt caaatttttc aacaccttga
     4321 ttgaatcaca ataatcatca tttatattgg atgttaacaa gagcagcttc ttgctctttg
     4381 tgtatttcaa aaaagaaatg aaaggaaatc atatgtataa attattaact tctggaccat
     4441 tgacgacttc tgaaacagtg aaaaatgcta tgctgatcga tcattgtact tgggatcaag
     4501 aatacaaaga aattacacaa tggataagaa aaaaattatt ggatcttgct caagtatcgg
     4561 aaggaatata cacaacggtc ttaatgcaag gtagcagctc cttcggggta gaatcggtat
     4621 taagttctgt gatcaggcca gaagatactg tactgatttg ttcaaacggc gcatatagac
     4681 aacgaatgat caacatgtgc gaatgtctga aactgaacta taccgtttat gaggtatcgg
     4741 aacatcaaat cctccaagct catgtgatta cacagctgat tgaagagaat ccgtctatct
     4801 ccgcactagc aatggtccat agcgagacta cttccggtat tttgaataat ttggaagaga
     4861 ttgctgctgt cacacaagaa agagatcttt tgtttatagt ggacgcgatg tcaagctttg
     4921 gtgggatacc gatttgtgta gccgaactag ggattgattt tttgatttcc agctcaaaca
     4981 aatgtattca aggtgttcca ggcttttctt ttgtacttgc taataaagcg gaactggaaa
     5041 aacgaaaaaa tgttagccga agtttgtcac ttgatctata tgaccagtac cgcgtgatgg
     5101 aaaacgagaa tggcaaatgg cgtttcactt cccctaccca tacggttttg gcttttcaac
     5161 aagcgctgaa ggaactagag gcagaaggag gaatcgaaac tcgatattca cgttatctcg
     5221 ccaataatca tgtgctacga caaaaaatga cagagatggg gttccagcct ttcattcaag
     5281 aatatcaggg gccattcatc acctcttttc tttaccctaa ggactggcga tttgatttta
     5341 atcattttta tcagtattta aagcaaaatg gatttgtgat ctatcccggg aaaatcagcg
     5401 atcatgaatg ttttcgtatc ggaaatattg gcgagatcta tccggaagat attttggaac
     5461 tgacagcaat tatcaaagac tataaggaga acgttaatga ttaaaactgt aatttttgat
     5521 tgggcaggaa caactgtgga ctttggctgt atggctcctg tccacgcttt tagaaatgct
     5581 tttctagaaa aaggaaccca actgactgac aaagaaatcc gctaaccgat gggaaaatta
     5641 aaatgggatc atatccaaca gcttctttcc ctcccttctg tcaaaaaaca atggatagct
     5701 atttatggac aactacctca ggaaaaagag gtggaggaat tgtatcaaca atttgaacat
     5761 tatctgttta aagatttggt caagcattct accttgaaac ccgacacatt ggaaacgatc
     5821 gaacggttga gaaacgctgg gatcaatatt ggttccacga atggatttaa tgctcctatg
     5881 atgacaatcg tagcagaaac cgcaaaaaaa gaaaggtatt caccagactt catggcaact
     5941 tttgaagacg tcgaagggta tggtcgaccg tttccttata tgatccataa aaacatgcag
     6001 tacttcaaaa acaagtcggt tgatgaagta atcaaagtcg gagatacggt ctcagatatc
     6061 caggaaggga aaaatgccgg agtgttgaca gtaggtgtaa ttgaaggtag ttcgctaatg
     6121 gggatttctt atgatgagta ccaaaaatta gagatgggga aaaagatcgt ttaaaacagt
     6181 ctgttgctct tagattccaa caagccggcg ctgatatttg tgtaaacaat ttaaaagagt
     6241 taacagaata cattttgtac gctgacaaga atccagaatg acttttatac aaaataagag
     6301 gttgtgaaaa agctgtcctg tatcaagtaa taaaaacagc caagcaaaaa tagctcctca
     6361 tatttttcgt ttggttaggc ttattaccgc agatgcaagc ttttgaacac cgtttattcg
     6421 aaaaaaaaaa gggagctgtg acacgacttt tgtcacagtc cccttatttg caaacaaaca
     6481 gtgtttaaga gacaacctct ccactaaacg gtgttcattc agctgactct cggtatttgc
     6541 tcaaaaaacg ataaaatttg aaaagctatt ttctcttttg tttctctaat actcggatca
     6601 gaacgctgat ttcacattct ctttttctta catcttatct ggtgcatgaa gtcctagcaa
     6661 acgaaggtct tctttcaata atacagtcac tgcataaact agagctaagc gtgcttcttt
     6721 ttgttcatca tcagctaaaa tcttcgtatg agcatagtat ttgttgaatg cttgtgctaa
     6781 tttgattgca tgtttcgcaa tcactgacgg ttcgtatttt tccccagcag acaagaccgt
     6841 ttcagggtat ttttgaacta atttaaccac ttcccagctg gtatcgtcat tcaatgcata
     6901 gtctgctgtt tctgaaggga caaatcctgc tttttccaac aggctgactg cacgagcatg
     6961 tgtatattgc acataaggtc cagtttctcc ttcaaatcga acaacttctt ccaggttaaa
     7021 gtcaaatgta ttcagtcgat cgtttttcaa atcgtggaaa atgactgccc caaccccaac
     7081 ttgtttagct acagcatctt tgttttccaa atcagggttt ttctcgctga tttgttcttt
     7141 agcagattgg attgcttcat ttaatacttc ttctaataag acgatctttc ctttacgagt
     7201 tgataatttt ttaccacctt gcgtgatcaa accaaatgga atatggtgca tgtcgtcaga
     7261 ccagtcaaag cccatttcct tcaagacagc tttcaactgt ttaaaatgat agctttgttc
     7321 attccctact acatatagag attgtttgaa gtcgtaagta cgtttacggt acaatgcagc
     7381 agctaagtca cgtgtaatgt atagtgtcgc accgtctgac ttcttaatca acgctggatt
     7441 caggtcataa gcagataggt caacgatctc tgcaccttta tcctcgttca gcaaatgttt
     7501 ttcttctaaa agtttgacga tttcatccat cttgtcattg tagaaagctt caccgttcaa
     7561 cgaatcgaaa cgtacttcca gcagatcata gattttattg aattctttca tcgattcatc
     7621 acggaaccat tgccataatt gaatagcctc tttatcgcct tcttccagac gtttgaacca
     7681 agcacgagct tcttcattta attctggttc tgtttcagct acctcatgga attggacgta
     7741 taaacgaagc aattcattga ttggttctgc tttaacagct tcttctgtac cccatttttt
     7801 gtaagcgacg atcagttttc caaactgtgt tccccagtca cctaaatggt tgatgcggat
     7861 tggctgataa ccgatttttt ccataatgaa accgatcgaa ttaccgataa ctgtcgaacg
     7921 caaatgtccc attgagattg gtttggcaat attaggagaa gacatgtcga ttggtactgt
     7981 tccttgattc ccgatgttgc tatccccata atgttctttt tctttcacta ctgtttgcaa
     8041 aacttttttg ctgataagtt ctttattcat gaaaaagttc aagtaaggtc cgacaacttc
     8101 gattttttca aagttggcag aatcgatttt ttctgctaaa tctgcagcga tttgctgtgg
     8161 cgcttttcgg taaacttttg ctaatgaaaa ggctggaaat gcaacatctc cgtgttcagc
     8221 tgattttgga ttttctagta attgctcgac ttgttccagt gttaaatcat ctttgacagc
     8281 gtcatagaca gcttttgcga caagatcttt attattcatc tttattcctc ctaaagtgtt
     8341 cccttgattg ttaaacaaaa aaaatctcta gcgacggcat acttagtatg ccatcactag
     8401 agacgagatt tcccgcggta ccactccaat tgtcctaaaa aaggaccagc tccatctgat
     8461 atcggtagac gaccgtctgt ttaaaacaga attctccaag tgcgcttcgt tgtatcttct
     8521 tcattcggct tccaccactt ccgaattcgc tagccaagaa tgatacaagt actctcttgt
     8581 tcaacaaatc ttagtcttat taaactttct tgaattatat cagaaaaaaa aacgaaaggc
     8641 tagtcgtttc ataaaaaaaa
//
LOCUS       DAFEKH010000087         8490 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.090, whole genome shotgun sequence.
ACCESSION   DAFEKH010000087
VERSION     DAFEKH010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8490
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.090"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..173)
                     /locus_tag="LP386_002670"
     CDS             complement(<1..173)
                     /locus_tag="LP386_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006735101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1919854.1"
                     /translation="MATKIADELENHVLETGMQKITTHASITAKPFFEKRGYKVINEQ
                     TVELRGQLFTNFL"
     gene            complement(593..1714)
                     /locus_tag="LP386_002671"
     CDS             complement(593..1714)
                     /locus_tag="LP386_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HBL1919855.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVMDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYKPG"
     gene            2042..3451
                     /gene="istA"
                     /locus_tag="LP386_002672"
     CDS             2042..3451
                     /gene="istA"
                     /locus_tag="LP386_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HBL1919856.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            3448..4176
                     /gene="istB"
                     /locus_tag="LP386_002673"
     CDS             3448..4176
                     /gene="istB"
                     /locus_tag="LP386_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HBL1919857.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSY"
     gene            complement(4304..5215)
                     /locus_tag="LP386_002674"
     CDS             complement(4304..5215)
                     /locus_tag="LP386_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL1919858.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGLALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(5232..6239)
                     /locus_tag="LP386_002675"
     CDS             complement(5232..6239)
                     /locus_tag="LP386_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBL1919859.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSSPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(6236..8365)
                     /locus_tag="LP386_002676"
     CDS             complement(6236..8365)
                     /locus_tag="LP386_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBL1919860.1"
                     /translation="MKKKLFRIVGIVFISIVLLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSSTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(8370..>8490)
                     /locus_tag="LP386_002677"
     CDS             complement(8370..>8490)
                     /locus_tag="LP386_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL1919861.1"
                     /translation="GQCLMQDLYGRVGVVQVHPVFEELFHAFDTRPPVQERME"
BASE COUNT         2600 a         1726 c         1485 g         2679 t
ORIGIN      
        1 attaaaaagt tagtaaataa ttgccctcta agttccacgg tctgttcatt aataacttta
       61 tatcctcgtt tttcaaaaaa tggctttgcg gtaatggaag cgtgggtagt gattttttgc
      121 ataccagttt ctaaaacatg gttttccaat tcatctgcaa ttttagtcgc aatacctttt
      181 ccttgatggc tatgtttttg tcacaacttc agtattcctg taacaatacg gatttcagta
      241 tacaacaaca gcttttgaaa agatacttgc aaaaggatta agatatctat gacctgctat
      301 gctcactgat gttgaaaaga atgttttatt aggattgagg taagcaagat agtgaatatg
      361 tccggaaagc ctgtaaaata aggcttttcg gacatatgtg aagttataaa aagatagcga
      421 aaaatctatt tagtatcact aatgttgcga acatatcgtc agaatagtct gacatttatt
      481 tcttgctaaa aatttcaaaa aagtcaagtg ctgacgcagc ggatgactat tttccagaaa
      541 attttagtat gtattcaaaa atcaaacgtg acaacagcta ttaactacat cctcatccag
      601 gtttgtaacg tttgaaccac tcttctgcgg gctcaaacat taagtaatgg aaggtacgtt
      661 tcaattgaaa cagcgtcgct gtcgtattca actcaatttt tatcacataa gtgagaagcg
      721 ttgcgattaa ggtgaggatg acttgattta tcgccccttg ttcactatgt gaatatagtc
      781 gtttaatggt cagattttgt tttaagtgtt tgaacaacaa ttcaatctgc caacgggctt
      841 gatacatgtc ggccacttcg tttggcgata catcaaagag attggtcacc attcgcagga
      901 ttttttgtcc cttggtaaga accgttacca acctaaaacg ctctgtcaca tggttgacac
      961 cgccgacaag aatcacttgt tggtcactga ttatcgtccc atcacgggtt gttgtatctg
     1021 ctacttcaat ttgatccaag atggtaattt ttgtattaga ttttgtccgt gtaacgaaga
     1081 aatagccgtc acgatttagt ttgtctaaca acttgtaatc aaagtagccg cgatccatca
     1141 catacgttgc ttgcgtttta tcaacaagaa cttcaaggtg attacggtca tgctcactcg
     1201 catttgtcat cgtaaaactt tcaggatact gattggtttt atcaagataa cagagattca
     1261 aatgtagctt gatgccagac tttgttttcc gaaacttggc ccatggaaac catgctttgt
     1321 tcaacggaat agtcgttgaa tcaatcaatt gtagactggt tgtttttgag cttggctgct
     1381 gagcagaaat tctggcgact aattgcgtaa aaatttccat caatacttct tgcttgattt
     1441 ctggcgctct acgagataac gagctgtaac acagggaatc aatgccaagt tccttgcaga
     1501 ggcgctgatc taaaaaggcg cgatcaatct cgcgatagct tggcaattct tcataaaccg
     1561 catgaagtaa cactttaagc gtcgtttgga agtctagttt tttactgtag aaatcaaagt
     1621 cgctaattaa gctttgagag ttttctgata aaccagaaaa atttattgca gaaaaccatt
     1681 tttgaaatga ggtttttacg ttatacttat ccatgcgtga gtccttttta ttggtcttgg
     1741 ataagtcatc cgagaatagt ataaaggact tttttgcgtt tggatagctt tgtattaggc
     1801 ttttgatggg ttaaaaagtc tttgcaacac tagtaattta gtatttatgt ataaattgaa
     1861 agatatttta ccaccactta gtcttcttaa aagtgatcca acattttgtt tgtggcagaa
     1921 tttaactaca cactaatgca gccgaaagta cacaactatg cagcagtttg actgcgaact
     1981 ggtttccttc catcataagt ttgaatgact tagtgatgga ggtacagaaa ggttgttaac
     2041 tttggatgat attaaaacaa taaaacattt gagaaataat cgtgatcagt caattgatca
     2101 gataagaaaa gcaatgaata tcaattggcg aacagcgaaa aaatacgccg atagtgatca
     2161 actattcatt acagatccca ctcgaaaaaa caaatccatg atggatgatg gttggggaga
     2221 aatcatcggt agttggctag aagaagacct acgtttacgc agaaaacttc gtagaacggc
     2281 caaagctatc catgaacaat tgaaaccttt gggtttccct ggctcctatc gaacagtttg
     2341 tgtatacatt tctcaatgga aaaagcagcg ttacgacgaa acgaattacc aagctgtcga
     2401 tcgtcttgat catccgatcg gagaagcaca ggtcgatttt ggaacaatgg aagttatgca
     2461 tgaagatcac atgaaagata tacaacttct tatcatgtca tttccctata gtaatgcgac
     2521 gtccgcaagt gccatgccag ctcaaaacca agagtgtttc ctggaagcat taaaacaact
     2581 atttaatcaa tgcggcggcg ttccaaaaac gatcagaata gataacttaa ctccagcggt
     2641 gaaaaaaaca aaatcaaaat ttgaagaagc acaactaacc gatgaattct tacgtttcac
     2701 cattcattat ggttgtgatg ttcaagtctg taacccacgt agtgggcatg aaaaaggaca
     2761 tgtcgaaaat aaagtgggtt atgtccgata caatttcttc tcgacttcgc caatcatgga
     2821 ctcttttgag tccctaaata agcaacttga agaacaatta aaagcagatc gaaaaaggac
     2881 gcattattca aaacatcaat taatcgaaga tttgtggaag aaagaaaata aagcgttaca
     2941 ttctcttcca caagaggatt acccaatttt taaagaagtg gaagctaaac taaatcgtta
     3001 tcacgaaatg aaattggatc aaacggttat tcatattcct aaagcatatg gctattctca
     3061 attgactgtt gttttgactt ggaataaatt caaagttctt acgcctcatg gagaaatatt
     3121 aatgaacgaa tatcgcccct atatgaacaa aaaaagattg atcccatgga gtgacatcat
     3181 gaaacaatgg agtaataaat tgaatgtcgt tagttattcg aggtattgga agtacttgcc
     3241 tgcacgcctt caaaattatc tagcgattga taataatcac ctgaaataca gacggataaa
     3301 acaattacta agtttattag cgacctacga tatccaacaa attaatgaac aattttacga
     3361 attagtcgtt caagaagacg ccccctctga ctttgatgtg aattggtcaa actatgatgc
     3421 attaacaaaa acaggaggtg tgcaaaaatg attggacaga cgttagaaga ttattgtaaa
     3481 aagcttcgat taagccatat catcacgaac ataccaagag cttctttcga agctccagaa
     3541 caatttatta ccgatttatt ccgtttagaa ctggagacca gacagcagat caaattagaa
     3601 cggatggaaa aattagccaa atttcctgta ccaaaatcgc taaagaacta tgaatggcac
     3661 gaagatattt ttctaccatc tcatctagat aaggagaccc ttgtctctct tgattttcta
     3721 aaaaggcaag aaaacattgt ttgtgttggc tctcctggta cagggaaaac acatctagcg
     3781 atcgcattag ggagaaaagc ctgtagtgaa ggtgtttcaa ccaaattttt ccgagttaac
     3841 aatctcgtag agcaattaga gaatgcatta aaaaaacaac agctagccag tttcaagaag
     3901 cgattcgaaa caacagaatt aattattctt gatgaaatgg ggtacttacc attgacaaaa
     3961 gaaggagctg aacttctctt ccaactgatt tcagattggt atgagcaaaa gagcattatt
     4021 attacctcta atttagaatt cagtcaatgg aatcgagtgt ttatggattc tcgattaaca
     4081 gctgctctcg ttgatcggct aatccatcac gctcacatta tcagcttcaa aggcgaaagt
     4141 ttcagattga aaaattcatt atctaaatca tattgaagga aaaaactagt tgcagcaaaa
     4201 ctctgcactt tcggctgcat ttttttgtaa aaagctattg cacaacacaa acatttgaac
     4261 gacgtaattc caaatgttgg attgctttta gataatcttt tatttattca caattgctaa
     4321 tagtccaatt ttcatttttg tatagtttta atctatactg aaaaacactt gttgttttgg
     4381 acaactcatc aagatactca acaccaacaa tcacttgaat cgctttaccc ttttgtttgt
     4441 aaataggatt cactaattcc acaaatttca aattagtatt aattggttgc atcgcgtctt
     4501 tttcaacata atgctctagt tctttttctg aggctgctgg ataaagcctg aaaaacgtct
     4561 ctaaaaactc ggtgatttct tccgttgtct ttgaatcaat ttttgaatca ctttttactt
     4621 gtcttacttt atgttttgcc ttttctggct taccaatcat agtgggtaaa ctcgttacaa
     4681 tatgattgcc tttttcatct tcaaagatca tcagacgata tgcagaagaa attgattgtg
     4741 tctttttccc ttctgtaatc ttttgatcta ccacaaatga aacgacaaat tcttccgagt
     4801 gtttttcaac atctagaatt tttactgata caacctcgga actagtggga atatccgctc
     4861 gaaccatatc ttggctcaaa gcgagccctt cttctgtaag gtactgctca agattagtca
     4921 ttctcttttc aattacctcc ttgttattct tccatgaaaa atattctttc acaaaatcta
     4981 cagtaaaatt ttctactcca gaggtattca ctattttctc tttcacgacc actttctcat
     5041 gagttgtatg ctgatcaatg gccgtgaagt ttttgtagat tccaaaagca aggctacaag
     5101 acaataaaag ccaaagggca agcaccattt ttcgatgctt gcccacggat actactcgtt
     5161 ctttcttctt ttttggaatc ttttccttgt tacttcgctc aatttttatc ttcattttcc
     5221 attcctcttt tctattgttt ataccgacca gcaccaataa tgtgctgttg ccaatagcta
     5281 tcggtaagat tggtccaacc caccggatct cctgcatgaa acattctgtt ctctcctgca
     5341 taaatgccca catgagtcac ataagtaccg gcatcataag ttgaatgaaa gaaaatcaaa
     5401 tcgcctggtt tggcatcttt taagtcaata tgagtcatag catcatattg atcctgagcc
     5461 acccgaggga gtttcaaacc aactttggca taacaccatt gagttaaacc actacaatca
     5521 aacccagttc cgggacttga cccaccaaat acataagccg ttccttcata cttgaacgcc
     5581 tcgtcaaaaa ttccttggac tgttttatca tcaaactgtg ttgtagttag gtactgcttc
     5641 actaataagc aataaaacat attgccatag ttataccgcc acccactatt ttccttaatc
     5701 gcgatgggat tgggataatc gactttttga ccacccgatt tttcttttga aaaagattcg
     5761 gctaaagcaa aactatgctt ctttccgttt ttcgcgacat aatccaaata cccgtcacca
     5821 tagttataag cctgaatgat actatcttga tcgcatccta gttctttgga acacttaacc
     5881 aaagacgaaa aatagagaca cacttgtttg atggatgcct cggtacttaa tgaattcggt
     5941 gataaacctg ctgattcaga actttgcatg acatcttcca ttgtacctcc agattcgact
     6001 tgaataatcg ccaaaagaat cgaaacatac tctgttatat ctgattcttt ggcatacttt
     6061 tccaccattg aacggtgttt caaaactact tctgagacac tactacctcc aggagaagtt
     6121 ccagaactac cacttccctc accgtcctca ccaaacaaca aacccacaca catcaagatg
     6181 cccacaaaag agatggtcag gaaggttaac gaaataatac tcaatttttt taagttcatc
     6241 ttttctcacc tggctttggt tttgggcgag tgttcttttt tctttgtact tgttgattgg
     6301 ttcgctttgg aaaagtgaat ctctgtttca cttgttgaaa ggaattgttc ttgcttagtg
     6361 gctgagtgct tccgtttgga atgacttctt gactagaaag tttccgtttg atttcaggat
     6421 tcgaatgtac ttgtaccctt ggttttaaag acctattttc tggtagttca tttttctgtg
     6481 gttttatctc cttttttatc ggaacatttt cccttccttt ctcatgacga ttccatgctt
     6541 cgttcaatac tttgcgtttt tcatccattt ttgcgtctct tcgttgtcgt tgtttttctc
     6601 gcaactcccc tcgatttgct ttttcttcga aaggccctcg cttaaagtcc tctggtactt
     6661 ttttcgtctt ttccatgcct ttatgaaggc tgtatttcaa gttagttggt gcatcggtta
     6721 cttgattttt tgcttgtttc gctttgtcct tcacgatttc ttttgtatcg agtacttttc
     6781 caacttttct accaactaaa tttattcgtg attctttctt cgtgcccact ggttgttctt
     6841 gttttttcag atcagaattt agctcgttaa tgcttctcgc ggaatggttc tttctattgg
     6901 acactctatt gatttttgaa ctacctttcc cttttgtaga actggtagct agtttcccac
     6961 caactgctgc accgccacca aaagcaaaag ttcgacccac atttcgatta agctgtcgca
     7021 attttcgatt catcaacatt tgcggtttcc gcatgactcg ccttcccatt gactgactat
     7081 cattactttg aaggttaaac atgctcataa tgtcacctaa tttgaaatag ataccggcaa
     7141 aggtcacaat ttgtagaaaa gctaccataa agaagggata ggtggccgaa atattgaaaa
     7201 acatcgtgga gatactgaat gcagtcgtaa tgactaaggt aactcccgct cgcatcataa
     7261 tcgtattgaa caaacgaata atcgcccttt tgcccaaact ctcatacgtc ggcaacatcg
     7321 acaataagaa actaatgggc agaaacatcg caaagataat gaaaaggatt tgtgagaaca
     7381 acataatccc tgtcagaaga aacacaaaaa aggaaatccc aatattaaac aacactaaaa
     7441 agaccacggt tcctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattat
     7501 cttcaatctc tgctttgact gcttcttccc gatccttacc cttattttca tccggactca
     7561 cggataaaat cttattaacc cgaccctcgc caatttcttc tatattggaa tcatcgaatt
     7621 gtaatagtaa ccagggttgt tgaacttgaa tcgaaaataa actgtctcga atcaaatcca
     7681 cactatcttt tccctggctt tctgaattag gtacaacaat cttggttcca aggctaagag
     7741 ccgcttcact aacgtctgag ctaaagtcat tgatttttgt aatataggtg ggcgcatacg
     7801 caatgaaaga acccgagagt agaaaaatca tcacaaaatt aatgacggtt cggactgctt
     7861 tggtagtttc tcgttttaat aatccggtat acgccacata aactcctaga gctaaaatca
     7921 tcaataatag gaacccaaag tagaatcccg aagtctgtaa tccattttca gtgataccgg
     7981 ctaaagtttg gatattcttt ccaatacttt tagccgtatc cgaaatgaaa tccaacttgt
     8041 aagcttcttg aaccacatag cccgtggcgt ttgataaata cagacttact gtccaaataa
     8101 aattggtaat ggcataaaga ccatacatca cgcttttccc taagccatcc ccccaattcc
     8161 aaggtaacca atcccaagaa ctatccacaa agaaatccag ttgataattg ttcagagaat
     8221 atttggaata aaggtttccg gcttcaactg tatcatcaac cagacctgtc gcctcagcta
     8281 ccgtaccgac taaactcaat agaactgtca ataggacgat gctaataaaa acgattccca
     8341 caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac cggcggacga
     8401 gtgtcaaaag catggaagag ttcttcaaag actggatgaa cttgaaccac acctactcgc
     8461 ccatacaagt cttgcatcaa gcattgaccg
//
LOCUS       DAFEKH010000088         8298 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.091, whole genome shotgun sequence.
ACCESSION   DAFEKH010000088
VERSION     DAFEKH010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8298)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8298)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8298
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.091"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            47..679
                     /locus_tag="LP386_002678"
     CDS             47..679
                     /locus_tag="LP386_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBL1919862.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGNQSYLDAKN
                     MVLRESHIQKLTMQKTGLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTTIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(681..1586)
                     /locus_tag="LP386_002679"
     CDS             complement(681..1586)
                     /locus_tag="LP386_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBL1919863.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWEIALIISLVLSIWMLIALWRRIR"
     gene            complement(1671..2330)
                     /locus_tag="LP386_002680"
     CDS             complement(1671..2330)
                     /locus_tag="LP386_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBL1919864.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     CVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVS
                     I"
     gene            2646..3590
                     /gene="mvk"
                     /locus_tag="LP386_002681"
     CDS             2646..3590
                     /gene="mvk"
                     /locus_tag="LP386_002681"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HBL1919865.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            3583..4560
                     /gene="mvaD"
                     /locus_tag="LP386_002682"
     CDS             3583..4560
                     /gene="mvaD"
                     /locus_tag="LP386_002682"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HBL1919866.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKKGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            4573..5658
                     /locus_tag="LP386_002683"
     CDS             4573..5658
                     /locus_tag="LP386_002683"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HBL1919867.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            5655..6719
                     /locus_tag="LP386_002684"
     CDS             5655..6719
                     /locus_tag="LP386_002684"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HBL1919868.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKDPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAQEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(6968..7771)
                     /locus_tag="LP386_002685"
     CDS             complement(6968..7771)
                     /locus_tag="LP386_002685"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HBL1919869.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIRDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(7791..8096)
                     /gene="kduI"
                     /locus_tag="LP386_002686"
                     /pseudo
     CDS             complement(7791..8096)
                     /gene="kduI"
                     /locus_tag="LP386_002686"
                     /inference="COORDINATES: protein motif:HMM:NF002091.0"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
     gene            complement(8078..>8298)
                     /locus_tag="LP386_002687"
     CDS             complement(8078..>8298)
                     /locus_tag="LP386_002687"
                     /inference="COORDINATES: protein motif:HMM:NF018513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HBL1919870.1"
                     /translation="ALGIMLVAFIVAKKNKYPVVEKGQMAHAGKIIKEAIPSLLLIVI
                     IIGGILTGIFTAVEASAIAVIYKWVIRF"
BASE COUNT         2505 a         1740 c         1625 g         2428 t
ORIGIN      
        1 gattcccgct tctttgctat actaaagaaa aacgaggtga acccacatga aaaaaatcga
       61 acctattcca ccttctcttc ctcttcttac aaagggagag ttttatttag aagatgagga
      121 gatcttctct ggtcttctga tcaacggagg taaccaaagc tatctcgatg ccaaaaatat
      181 ggtattaaga gagagtcata tccaaaaact tacgatgcaa aaaacaggtt tacgtcattt
      241 tgaatgcagt aatgtcattt ttgaaaaatg tgatttttcc aatctggagt ggattggtgg
      301 cagtttccac caagtcgtgt ttcatcaatg taaattaaca ggtacgaatt ttgccgaaag
      361 ttatcttcga gactgtactt tcactgattg tattgcttcg atggcttcct ttagtagtac
      421 aaacttgaaa gctgtctcct tcgatcattg tcaattagaa gacagcgaat tttatgaggt
      481 cacttggaaa aacctttttt tgtctgacaa tcagttaacc ggttcgaact ggtttcgaac
      541 ttctctgaag ggattagact ttacgactaa tttcttcaca acaatcgctt tatctcaaga
      601 ttctttggcg ggactaatcg tcaatcaaga gcaagcactt gtgatcgccc aagcccttgg
      661 tttgcagatc aaagactaga tcaacgaatc cgccgccaca gtgcaataag catccaaata
      721 gataagacca aactgatgat caaggcgatt tcccatccga aaacggaatg ggtaaagggt
      781 aactggagat tcattccgaa gaatcctgtc acaatagttg gaacggtcaa gatcagcgac
      841 cagaccgtca aaaatttcat cgtgtcattc aagttgttat tcagcaaatt attataagtg
      901 ccagagagct ggtctaaaat ctgcgaagct aagttcgtca tttcaactgc ttgtcgtgct
      961 tcgatcagtg catcgtccaa ctcttctttt tccttttctg acaacttgcg ataaatagcc
     1021 agtgccttga tttgttctaa aagtactaca ttttgttttg ttcctgtaac taagtaaacc
     1081 aaaccgatct ctaaatctga aagttgcagc agattcttgt tcgttgtttt ttctcttaat
     1141 ttcagattaa gccgctgacg ttcactattc acttcctcga ttaaaggaaa aaaggaatca
     1201 gaaatcaaaa acaatgtacg aaacaataaa ctgtatacac tcatgtctgg catccgttcc
     1261 aaaagcgatc gaattagtcg aatcacgtac tcggtattcg gcgtggtaaa tgtaaacaaa
     1321 ccgtcttctt ttaaaataaa agcgatagga ctagtttcat aatgattatc gactttttgc
     1381 tggtgcggaa catttgatac aagcagtaac gcttcatcaa aagaatcgta ctctacgcgc
     1441 gcccgttcat ttttatctag agaataagtc agcatctcgt cactaatgcc atattcttct
     1501 tttaagtttt taacagctag cacatcgttt tgctgtacat tgatccaaaa attacggtct
     1561 tgattaaaat agtgtttttc ccgcatactc tatcctcctg acatttgttt ccagtataaa
     1621 gaaaaaagtc gctcaaataa aggtttaccc tttatttgag caactgtaaa tcaaatggat
     1681 actttggttt ggcgaatctc tgctaatttt tcttcgatca ttttcaagac ttcttctttt
     1741 gcttgaggat cttccacaaa attatagcgg tctccatcga tttggatttt tggactttct
     1801 ttgtattctt cataccattg atcataacgt ctgttcaatt ctttgtaata atcgtataga
     1861 cttgggtcaa aggacaattg ttcatacgaa cgaccacgtt tttcgatacg ctctaacatc
     1921 gtatcaaaag atacacgaat atgaactaat aaatccggat gttttttatg ggcagcatag
     1981 ggaagttctt ccatcatgtt ttccagcagt tcatcataca cacaaacttc tgtttctgtt
     2041 gctcttccta gatctgcatt tagatggaaa agcagtgaat cttcataaat cgaacggtcc
     2101 aatacattat tgtcatcttt cattgcttgt ttgatgcttg caaaacgttt attcaaaaaa
     2161 taaatttgca gcaaaaaagc atactgttca gggtttgcat aaaataaggg caagacttca
     2221 ttatcatcaa tcgattcata aaatgcctga ctatcaaagt gttcagccat catttctgtt
     2281 aaacttgatt ttccggcacc aattgtacct gctaaaacga tcacgctcat ttacctccag
     2341 ctcacttcat cactaaatat tgtgtttaac tccaaccttt tttaaatata cccccaatat
     2401 ctagtagtgt caattgtatt ttttctagtc aaagaagaaa aaaagtcaaa aaattcttaa
     2461 gaaaaaagtg ttttttcttt agaaaacgta ttcttagttt tacttctgag atggttttag
     2521 taaaataaag gaggaatgtt ttttgagacc cttagtggac aaaaaaattc gtgaagcagc
     2581 gcaactcgtt ttgggcgctt tattttttgc ttaaaaatca cttttacgtg agaaggagtt
     2641 agattatggc aaactatggc caaggagaat caagcggaaa gatcatattg atgggcgagc
     2701 acgcggttgt ttatggagaa ccagcgattg cctttccttt ctatgcaaca aaagtcaccg
     2761 cattccttga agagctggat gcaatggacg atcaactggt ttcttcctac tattcaggaa
     2821 atttagccga agctcctcat gcattaaaaa atatcaaaaa attattcatt cacttaaaaa
     2881 aacagcatga catccaaaaa aacttgcaac tgaccattga aagcacgatt cctgctgaac
     2941 gtggaatggg atcaagcgct gcagtcgcca cagcagtcac tcgtgctttt tatgattact
     3001 tagcatttcc tttgtctcgt gaaatactat tagaaaatgt ccagctttcg gaaaaaatcg
     3061 cccacggtaa tcctagtgga atcgatgcag ccgctactag cagcttgcag ccgatttatt
     3121 ttacaaaagg gcatcctttt gactactttt ctttgaacat cgatgctttt ttgattgtcg
     3181 ctgatacagg aatcaaagga caaacaagag aagccgtcaa agatgtcgct cacctctttg
     3241 aaacccagcc tcatgaaact ggacaaatga tccaaaaatt aggatacttg acgaagcaag
     3301 caaaacaagc aatcattgag aattcaccag aaacgttggc acagacaatg gatgaatcac
     3361 agtcacttct ggaaaagctg acaatcagca atgattttct taatctattg atccaaacag
     3421 caaaagatac cggggcattg ggtgccaaat taactggcgg tggacgcggt ggctgtatga
     3481 ttgcattagc acaaacaaaa acaaaagccc aagaaatcag tcaagcactt gaagatgcgg
     3541 gtgctgctga aacttggata caaggattag gagtacatac ctatgtttaa aggcaaagca
     3601 cgcgcatata ccaacattgc tctaatcaaa tattggggta agaaaaatga agaactcatc
     3661 cttccaatga acaacagcct ttcgttaaca ttggatgcat tttatacaga gacagaagtc
     3721 atcttttctg atagctatat ggtagatgaa ttttatctag atggcacctt acaagacgaa
     3781 aaagcaacaa aaaaagtcag tcagtttctt gacctttttc gtaaagaagc cggcctctca
     3841 ctaaaagctt cagtaatcag tcagaatttc gttcctaccg cagctggatt agcctcctct
     3901 gccagcgggc tagctgcttt agcaggagct tgcaatactg ctcttaagct tggattagac
     3961 gatctctctc tttcaagatt tgctcgacgc gggtctggtt cagcttgccg aagtattttc
     4021 ggtggtttcg ttgaatggga aaaaggccat gacgacttaa gttcttacgc taagccagtc
     4081 ccttccgatt ctttcgaaga cgatttagca atggttttcg ttttgatcaa cgaccagaaa
     4141 aaagaagtgt ccagcagaaa tgggatgcgt cgaacagtcg aaacatccag tttttatcaa
     4201 ggctggttag attccgttga aggggatcta tatcaattga aacaagcaat caaaacaaaa
     4261 gatttccaac ttctcggaga aacgatggaa agaaacggac taaaaatgca tggaacgact
     4321 ttagctgccc agcctccatt cacttactgg tctcctgaca gcttaaaagc gatggatgcg
     4381 gtgcggcaat tgagaaaaaa aggcattcca tgctacttta cgatggatgc tggccctaat
     4441 gtcaaagttt tagtggaaaa cagccattta tctgaggtac aagaaacatt taccaaatta
     4501 tttagcaaag aacaagtaat tactgcccat gctggtccag gaattgcgat tattgaataa
     4561 agggagattt ttatgattga agtatctgca ccaggcaaac tctatattgc cggagaatat
     4621 gcagttgttg aaacaggaca tccagcagtt atcgctgcag tcgatcaatt cgtaacagtc
     4681 actgtagaat ccgcacgaaa agtcggaagt atccaatctg cacaatatag tgggatgcct
     4741 gtacgttgga caagacgcaa cggagaatta gttttagata ttcgggaaaa tccttttcat
     4801 tatatccttg ctgctattcg tttgactgaa aagtatgcac aagaaaaaaa cattctttta
     4861 tccttttatg atctgaaagt aacaagtgag ttagacagtt caaatggccg gaaatatgga
     4921 ttgggttcta gcggtgccgt gaccgttgca acggtcaaag ccttgaatgt tttttacgcg
     4981 ttgaatttat ctcaattgga gattttcaag attgcagcac tagccaattt agcagttcaa
     5041 gataatggtt cctgcggcga catcgctgct agctgttatg gtggctggat cgctttctca
     5101 accttcgacc atccttggct ccaagaacaa gaaactcagc attctatcag tgagttactt
     5161 gccctggatt ggccaggtct atccattgag ccattgattg ctcctgaaga tttacgttta
     5221 ttgattggtt ggacgggtag ccctgcctct acttctgatt tggtcgatca agttcaccgt
     5281 tcgagagaag acaaaatggt ggcttatcag cttttcttaa aaaacagtac agaatgtgtc
     5341 aacgaaatga tcaaagggtt taaagaaaat aatgtaacgt tgatccaaca gatgattcga
     5401 aaaaaccgac aattactgca tgatttatct gcaatcactg gggtcgtcat cgaaacgcct
     5461 gctttgaaca aattgtgtaa tttagctgaa cagtatgaag gagccgcaaa atcttctggt
     5521 gcaggtggtg gcgattgcgg aatcgtaatt gttgaccaga aatctggcat ccttccttta
     5581 atgagtgcat gggaaaaagc agaaatcact ccactgccgt tacatgtcta tagcgatcaa
     5641 agaaaggaaa accgatgaat cgaaaagacg aacatgtttc actagctaaa gcctttcatg
     5701 ataaacaaaa aaacgaattt gacttcgtac ggatcatcca taaccctttg ccgcaaatag
     5761 cagtttctga tgtcgatcta agtacacagg cagttgggtt tacactaagc agcccatttt
     5821 atatcaatgc gatgactggc ggaagcgaaa aaacaaaaaa aatcaaccaa gatcttgcaa
     5881 tcgtcgcaag agaagcagat ttgatgattg ccactggttc agtcagcgct gccttgaaag
     5941 acccttcttt agccgatact tatacgatta tgcgacaaga atatcctcac gggaaaatca
     6001 ttgccaacat cggtgcaggg acttctgtcg aaagagccca agaagctatc cgattgtttc
     6061 acgcagatgc cttacagatt catttgaatg cacctcaaga gttggttatg cctgagggag
     6121 accgtgattt taccaattgg aaagtactta ttcaagagac tcaaacagcc attgacgtcc
     6181 ccctcatcgt aaaagaagtc ggttttggca tgacaagaga aacgctcaat gatctagctg
     6241 ctttaggagt tcatacagtt gatatcagcg gtcgaagcgg aacaagcttc acccagatcg
     6301 aaaacgcccg tcgctccaag cgggaactga gttatttagc tgactggggg caatcgacag
     6361 tctcttcatt gcttgaagca aatgaagcag acacttctat ggaaatccta gcctccggag
     6421 gtatccgcaa tgcctatgac atatttaaag ccctttgtct cggcgcaaat gcagtgggta
     6481 cttcaggaac cgtactgacg catctgatga atcacggcgt agaagaaact attatactga
     6541 tgaagcaatg gcaagaagag cttcgtctgc tttatactat ggtcggcgca acgaataccg
     6601 cggccctaca ccaacaatca ctgatctttt ccggaccagt gaaggattgg tgcgaagcaa
     6661 gagggatcga cttagtgaag tatggaagac gcacagaaaa gagcgtggga caaaagtaaa
     6721 gaacactttt atcccacgct ctaaacacgt ataaacggcg gaagcaaaag caactccttc
     6781 ggaaataagc tgaaattcac aaaaatttga aaagcaattt tcgtgaattc cttcttattt
     6841 cttggagtta aacgcttctg tcccagcctc ttttttcgaa taaatgatgt ttaatcagct
     6901 gtccttcggt attcgttcaa gccgctgatt tcacaacctc tccactaaac ggtgtactaa
     6961 agctctttta aggttgtttt ccgatatagg caagtatgcc tccgtccaca tacaagacat
     7021 ggccgttaac gaaatcagat gcgctagaag ccaagaagac agatggtcca gccaaatcga
     7081 ttggctcgcc ccagcgtgct gctggcgtac gtccaacgat aaattgatcg aatggatgac
     7141 gttcaccgtt ttcttgtgtt tcgcgtaatg gagcagtttg cggtgtagca atataacctg
     7201 gtccaattcc attacattgg atattgtatt gaccgtattc agaagcgatg tttttcgtca
     7261 gcatttttaa tccgcctttt gccgcagcat aagcactgac cgtttcgcgt cctaattcac
     7321 tcatcatgga gcagatattg atgattttac cgccgccttt ttcgatcata tcccgaataa
     7381 ctgcttttga aacgatgaat ggggcattta aatccacgtc gattacttgg cggaagtctg
     7441 ccgcatccat ttcgatcatc ggtgtccgtt tgatgatccc tgcattgttg actagaatat
     7501 caactgaacc tacatcttct ttgatctgtt gaaccatcgc ttgaaccgct tcttcatcgg
     7561 tcacatcgca gacataacct tttgcatcga tgcctgcttc tttataatgc gctatacctt
     7621 catcaactga ttcttgattc aagttattaa atacgatttt tgctcctgct gtagctaaag
     7681 agcgtgcaat ctcaaatcca ataccataga cagcaccggt gactaatgct acttttccat
     7741 ctaaacgaaa catatccata ctaaattcca tcattttctc tcccttatgc ttattttaat
     7801 tgatccattt gcaccatatc catgtctgta taggtgatat tttctccgca cattgcccag
     7861 atgaatgagt aattgcttgt acctacacct gaatggatcg accagcttgg cgaaataatg
     7921 gcttgttcat tgtctacgac taaatgtttt gtttcatctg gtttgcccat catatggaac
     7981 acacgtgtat cttcattggc ataatcaaaa tagacataag cttccatacg acgttcatgt
     8041 gtatgacaag gcatcgtatt ccaagcactt cctggttcta aaatcgtata acccatttat
     8101 aaatgacagc tatcgctgaa gcttctactg ctgtaaatat ccccgtcaag ataccaccga
     8161 taatgatgac aatcaataga aggctaggaa tcgcctcttt tattattttt ccagcatgag
     8221 ccatctgtcc tttttcgaca acagggtatt tattcttttt agcaacgatg aatgctacta
     8281 gcatgattcc tagcgccc
//
LOCUS       DAFEKH010000089         8184 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.092, whole genome shotgun sequence.
ACCESSION   DAFEKH010000089
VERSION     DAFEKH010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8184)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8184)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8184
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.092"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            968..2218
                     /locus_tag="LP386_002688"
     CDS             968..2218
                     /locus_tag="LP386_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HBL1919871.1"
                     /translation="MKKQYNIAVAGTGYVGLSIATLLAQHHKVTAVDIIPEKVELINN
                     RKSPIQDDYIEKYLAEKELNLTATLDAKAAYQSADFVVIAAPTNYNSRTQHFDTSAVE
                     AVIRLVMEVNPDAIMVIKSTIPVGYTASVRVKTGSKNIIFSPEFLRESKALYDNLYPS
                     RIIVGTDMDDERLVEDAHTFATLLQEGAIKENVDTLFMGFTEAEAVKLFANTYLALRV
                     SYFNELDTYAEMKGLNTQQIINGVCLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYA
                     DVPENLIEAIVESNRTRKDFIADRVLQMAGYYNYAEANQYDAGKEKPVVIGVYRLTMK
                     SNSDNFRQSSIQGVMKRVKAKGATVVIYEPTLKDGETFFGSKVVNDLEQFKAMCDSVI
                     ANRYDACLDDIKEKVYTRDIFQRD"
     gene            2237..3247
                     /locus_tag="LP386_002689"
     CDS             2237..3247
                     /locus_tag="LP386_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HBL1919872.1"
                     /translation="MIITKTPFRMSFFGGGTDMEDYFKENGGAVLSTTFDKYCYVNVR
                     HLPRFFDYSAELSYSRTERVTSIEDIEHPAIRNAMKMLDVHEIRLTYEADLPARSGLG
                     TSSSFAVGMLNAFYALEGKYADKKKLADEAIYLERVLCNEAGGWQDQIAASYGGFNRI
                     NFNVDGYEVLPVIISPERKKQLNNNLMMFFTGFTRFSSDVQKANNVSGTEDKRVRLKK
                     MYELVDEAEAILTDKNRNLDDFGRQLDVTWRLKKGTGGAISTGSIDELYEKGMAAGAL
                     GGKLLGAGGGGFLVFYVQPEKQDAVRWAMRDLMYIPFEFEDGGTRVIHYTPETYIEKQ
                     NG"
     gene            3257..3910
                     /locus_tag="LP386_002690"
     CDS             3257..3910
                     /locus_tag="LP386_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL1919873.1"
                     /translation="MLAEKLNKHIDLLIKRYPTLETIKQDIIDGYLIMEECYLNGGKL
                     LVAGNGGSAADSEHIAGELMKRFKTPRPVSKEFADKLVAIDPVRGPELAKNLECGLTA
                     IPLVAHEALSTAYINDVDGLGVFAQQLFGFGRSGDVFLGISTSGNSKNIMSATVVARA
                     LGIKVIGLTGAKGGELATVADVCVKAPEVETYMIQEYHLPIYHCWCLMLEDKFFGNE"
     gene            3929..4927
                     /locus_tag="LP386_002691"
     CDS             3929..4927
                     /locus_tag="LP386_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HBL1919874.1"
                     /translation="MKKTIMVTGGCGMIGSNLVKRLVKEGCWDVYVADNLWRGKLEYL
                     NDEDGHPVIDLDTHFFNADLTDYEQAKKVIGTTEYVVHLADVVAGIDYVFKNQGELFR
                     INNLINSNVFDCCRKAGKEKIKGVIYVGTVCSFPLTRQNTLNPEPLREEELFPALPES
                     AYGWSKLMGQLEMGYLEKETGIPCCILMLHNVYGTPTDFGERSQVIPALIRKAINNPE
                     EPFNVWGSGEQGRAFIHVNDIVNALVLALDKGWGHGHIQIGPSHCTSIKEIAYKIIEI
                     SGKDIKPFFDTSKPEGDKARCADYSKAKEILDWKPTVSLEEGLRESYNWIEKQIKG"
     gene            5003..5764
                     /locus_tag="LP386_002692"
     CDS             5003..5764
                     /locus_tag="LP386_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HBL1919875.1"
                     /translation="MEKNMYKRKRDFTVCGIVGVCATTKNEFVREVFSMPTSPVSATV
                     DLVGVPAIISAKENPKIAEMYSQATMAAIDGMPIVKIGRRKGFTCERCAAPDIMGMVF
                     EEGVRQGKTHYFYGGKDNEVLNKLRANLERDYPGIKIVGMYSPPFRPLNEEEDSKICE
                     EINNLNPDFLWVGIGAPKQEMWMWEHQKKIHNTVMFGVGAGFNFFAGTLEKAPEWMEK
                     ASLEWLFRLVKEPRRLWRRYILGGIKYIYYTIESK"
     gene            5782..6888
                     /locus_tag="LP386_002693"
     CDS             5782..6888
                     /locus_tag="LP386_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBL1919876.1"
                     /translation="MKILIVVTMTNNFGKKGSYNSQEIGLARGLAELGHEVIVYKSVK
                     SDEEVGTEQLSNTAMIHYIKCRYVGSNGFLSTKNFDKNADVLIQFADLQLSVPHVYSW
                     TVKNGIKYIPYNGITRSQSGNKYIKTIIEILAHRNYKIYKKNGCVAKNDRVSEKLVQL
                     GVNKVKLAPVCVDFEQLHKNYEAIDFTTLREKWNIPRDVRVILYVGRFEKDKRPLDMI
                     SLFNKLDEHNYLLMVGTGALLEQTKQQINLLGLQNRVKIIERIPNKDIWELYCLSDVF
                     VNLNYTEIWGMVLLEAMYYRLGIIAVNAPGPQNIILDNRYGMLAKSDDEILTFLKDGR
                     FTNDIIDAAYQRVTTEFRWSKSGEIMLSMLEGDK"
     gene            6878..7111
                     /locus_tag="LP386_002694"
     CDS             6878..7111
                     /locus_tag="LP386_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919877.1"
                     /translation="MINDMEVTKLMALRNRYALNIVDNCTRKIAKILGCCIGKGAQIG
                     NSVEFVHNSVGTVIHSDTILEDGVKVYQNVTCG"
     gene            7310..7765
                     /locus_tag="LP386_002695"
     CDS             7310..7765
                     /locus_tag="LP386_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine acetyltransferase"
                     /protein_id="HBL1919878.1"
                     /translation="MNAYKLYKVERWFYLHKMEFFAKIVKALIYVLHNSSISYQTEIG
                     DNCKFLYGGIGCVIGKDTKIGNHVIIGTNVLTGGRSNKPGMPTIGNNVYIATGAKILG
                     NITIGDNVIVGANAVVINDVEPNCSVGGVPARVLKKDIDVNDYCSLNRY"
     gene            7779..>8184
                     /locus_tag="LP386_002696"
     CDS             7779..>8184
                     /locus_tag="LP386_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL1919879.1"
                     /translation="MLYFVIPLMSAKAANNWEMVSTLFNRTLWSCYNQTDPDFKIIVA
                     CHEIPKLTHEYDDRVEFIQVSEKDAPIPTNQDEKMIDKGYKTHALAMRLRELGGGFAM
                     MVDADDLVSSHLAEYVNSHPQENGFYVKTGYVY"
BASE COUNT         2547 a         1236 c         1952 g         2449 t
ORIGIN      
        1 ttaccaacat gtttagacat tttcctctag gaaaaaatta actagcacca cgggtgatat
       61 atatgtatat ggtgactgaa gacaaaaaaa cagaactaat gaaactgaat aaaaatatag
      121 agtgaactag tttctaagag ggattttaaa ctagatttca ttggtaataa aatttggaga
      181 gatggaaaaa cagcacttaa ggaagcagat tttgttgtca tttttgttcc tacaaactat
      241 ggtagtgaat gtgttattga attagtgatg tctgttattt cagaggcatt ggggataatt
      301 aaatccacta tacctgtagg atatacaaaa agtggaagaa aaaaatatta tcaatagatt
      361 ttatttagtt cagaattttt acgtgaaagt agattattaa tgataatctt tatccaatta
      421 gaattattat cgtaggatgt gatgatgaaa gccgtgaaat tgttcaagta tttaccaatg
      481 tctccctgcc agtaaatccg cttagaattt gagccttgaa aatgtgcaat gataaaaaac
      541 aaaaactcgc tcaaaataga cagtttgggg tgggaataga ccaataatgt accagacaaa
      601 cttccatttg gggtgaaaat aggtcaataa agcgatgtta aacatacctt tggagtaaga
      661 atagagggta ataagtgaat ttataaactt tttggtgact ggttgagtgg aaaatgtagg
      721 tacatttcaa tgcgaaaatg tattataacc ccaaacgagg tcaataaaaa tgactcaaac
      781 ttgcaatata accctaaacg ggtaggggat ttatgaaaaa ttgaatttgc cggcgtagga
      841 gctggctgtt ttaagtatga atgaacacag ctttcgggct gttttatata aatagcaggt
      901 tactgttcac aaacagcatt ttgttaagaa agtagtgacc acagcagtgg tggaaagagg
      961 aaatattatg aagaaacagt ataacattgc agtcgccggc accggttatg ttggtttgag
     1021 tattgccact ctgttggcac agcaccataa ggttacagcg gtggatatca ttccagagaa
     1081 ggttgaactg attaataacc gtaaatctcc aatccaggat gattatattg aaaagtacct
     1141 ggctgagaaa gaactgaatc tgaccgcaac attggatgca aaggcagcat accagtctgc
     1201 ggattttgtt gttattgcgg ctcctactaa ctacaatagc cgcactcaac attttgacac
     1261 atccgctgtt gaggctgtta ttaggctggt catggaagta aatcctgatg ccattatggt
     1321 tattaagtcc accattcctg ttggatacac cgcttctgtt cgtgtaaaga ctggtagcaa
     1381 gaatattatt ttcagccctg agttcctgcg tgaaagtaag gcactgtatg acaatctgta
     1441 tccttcgcgt attattgtgg gtaccgatat ggatgatgag cgtttggttg aggatgcaca
     1501 cacttttgct acactgctac aggaaggcgc aatcaaagag aatgtggaca cattgttcat
     1561 gggctttact gaagcagaag ctgttaagct gtttgccaat acatatctgg ctcttcgtgt
     1621 cagctacttc aatgagctgg acacttatgc agagatgaaa ggcttgaaca ctcagcagat
     1681 cattaatgga gtttgccttg atcctcgtat tggtactcat tacaacaacc cttcctttgg
     1741 ttacggtggc tattgcctgc cgaaggatac caagcagctt ctggccaact acgcagatgt
     1801 tcctgaaaat ctgatcgagg caatcgttga atctaaccgt actcgtaagg actttattgc
     1861 ggatcgtgta cttcagatgg ctggttatta caattacgca gaagcaaatc agtatgatgc
     1921 tggcaaagaa aagcctgttg tgattggtgt ttaccgtttg accatgaaat ccaattctga
     1981 taacttccgc cagagttcta tccagggcgt tatgaagcgt gtaaaagcta aaggtgcaac
     2041 tgttgtgatt tatgagccga ccttgaaaga tggagagact ttctttggca gtaaggttgt
     2101 gaatgatttg gaacagttta aggcaatgtg tgattctgtt atagcaaatc gctacgatgc
     2161 ttgccttgat gacattaagg aaaaagtata tacccgtgat atcttccaga gagactaaga
     2221 ttaggagaga gtatttatga ttattacaaa aacaccgttt cgtatgtctt tttttggcgg
     2281 tggaacggat atggaggatt atttcaaaga gaatggcggt gcagttcttt ctactacttt
     2341 tgataagtac tgttatgtga atgtgagaca tctgcctaga ttttttgatt acagcgctga
     2401 gttatcttat tctcgtactg agagagtaac tagcattgaa gatattgagc atcctgcgat
     2461 tcgtaatgcg atgaaaatgc tcgatgtgca tgaaattcgg cttacatacg aagctgattt
     2521 acctgctcgc tctggtctgg gtacatccag ttcttttgca gttggtatgt tgaatgcttt
     2581 ttatgcactg gagggtaagt atgctgacaa gaagaaactt gctgatgaag ccatttatct
     2641 tgaaagagtt ctgtgtaatg aagccggtgg atggcaggat cagattgccg catcttatgg
     2701 tgggttcaat cgaattaatt tcaatgtgga tggttatgag gtgctgcctg tcattatttc
     2761 gcctgaacgt aaaaagcagc ttaacaacaa tctgatgatg ttctttaccg gattcactag
     2821 attttcttct gatgttcaaa aggctaacaa cgtcagtggc acagaggata agagagtaag
     2881 actgaaaaag atgtatgagc ttgtagatga agctgaggca attcttactg ataagaacag
     2941 aaatttagat gatttcggta gacagcttga tgttacttgg agattgaaaa aaggtactgg
     3001 tggagcaatt agtacaggaa gcattgatga actatatgaa aagggtatgg ctgcaggtgc
     3061 tttaggcgga aagttgctcg gtgcaggtgg tggaggtttc ttggttttct atgtacaacc
     3121 tgagaaacag gatgcagttc gttgggctat gcgtgatttg atgtatattc cgtttgaatt
     3181 tgaagatggt ggaactagag ttattcacta cacgccggaa acttatattg aaaaacagaa
     3241 tggataagga gtaacaatgt tagcggaaaa acttaataaa catattgact tattgattaa
     3301 acgatatcct acacttgaga cgattaaaca ggacattatc gatggatacc taattatgga
     3361 ggaatgctat ttgaatggtg gtaaacttct tgtggcagga aacggaggat cagccgctga
     3421 ctcggaacat attgctggcg agttgatgaa gcggtttaag acgccacgtc ctgtaagtaa
     3481 ggaatttgcc gataagttag ttgcaattga ccctgtaaga ggtccggaat tagccaaaaa
     3541 tctcgagtgt ggtttaacgg caattccttt ggtcgcacac gaagcattgt ctactgctta
     3601 tattaatgat gtcgatggtt tgggtgtctt cgcacagcag ctgtttggct ttggtagatc
     3661 tggtgacgta ttccttggta tttcgacgtc cggaaatagc aagaatatta tgagcgcaac
     3721 tgttgttgct agggctctcg gtataaaagt tattggcttg acgggcgcaa agggtgggga
     3781 acttgccacg gtagcagatg tttgtgttaa ggctcctgaa gttgaaacat acatgattca
     3841 agagtatcac ttgccgatat atcattgttg gtgtttgatg ctggaagata aattctttgg
     3901 aaacgaataa aatttggagg aatgttaaat gaaaaagaca attatggtta ccggtggttg
     3961 cggtatgatt ggctccaatc ttgttaagag actggtgaag gaaggctgct gggatgttta
     4021 tgtagctgat aatctgtgga gaggaaagtt ggagtacctg aacgacgaag atgggcatcc
     4081 tgtcatcgac ctggatactc atttcttcaa tgctgatctg actgattatg agcaggctaa
     4141 aaaggttatt ggtacgactg agtatgtagt tcatctggct gatgttgtgg ctggcattga
     4201 ctatgtgttt aagaaccagg gcgaattgtt ccgaatcaat aatctgatca attctaatgt
     4261 ttttgattgt tgccgtaagg ctggcaagga gaaaatcaag ggtgttatct atgttggtac
     4321 cgtatgctcc ttccctctga ccagacagaa tactttgaat cctgagcctc tccgggaaga
     4381 ggagttgttc cctgctcttc ctgagtctgc ttatggctgg agcaaactga tgggccagtt
     4441 ggagatgggg tatttggaaa aagaaaccgg aattccgtgc tgtatcctga tgcttcataa
     4501 tgtttatggc acacctactg attttggcga acgtagtcag gttattcctg ctctgattcg
     4561 taaagcaatc aataatcctg aagagccttt taatgtgtgg ggtagcggag agcagggacg
     4621 tgctttcatt catgtcaatg atatcgtaaa tgcattggtg ctcgccctgg ataagggttg
     4681 gggtcatggt catattcaga ttggcccttc tcactgtact tccatcaagg aaattgcata
     4741 taagatcatt gaaatttctg gcaaagacat caagcctttc tttgatactt ctaagcctga
     4801 aggtgataag gctcgttgcg cagattattc taaggcgaaa gagattttgg attggaagcc
     4861 tactgtttct ttggaagagg gtcttcgtga atcctacaat tggattgaaa agcagattaa
     4921 gggttaataa gtatataagc tgttcttcct ccgtgtaatt agaggatgcg gaggaagaac
     4981 atatgagtaa ggatgtactg agatggaaaa gaatatgtat aaaagaaaac gtgatttcac
     5041 tgtgtgtgga atagtaggtg tttgtgctac tacaaagaac gagtttgtaa gggaagtttt
     5101 ttccatgcca acatctccgg taagtgcgac tgttgatctc gtgggagtgc cggccattat
     5161 ttcggcaaag gaaaatccca aaattgctga gatgtatagc caggctacaa tggctgcaat
     5221 agatggtatg cctattgtta aaattggacg gcgcaaagga tttacctgtg aacgatgtgc
     5281 tgcaccagat attatgggaa tggtttttga agaaggcgtt agacagggaa aaacacatta
     5341 tttctatggt ggaaaagata acgaagtgtt aaataagctt cgtgcaaacc tagaaagaga
     5401 ttacccggga atcaaaattg ttggaatgta ttccccacca tttcgtccgt taaatgaaga
     5461 agaggatagc aagatttgcg aggaaatcaa caacttaaat ccagattttc tgtgggttgg
     5521 tattggtgcg cctaagcaag aaatgtggat gtgggaacac cagaagaaga tccataacac
     5581 agtaatgttc ggtgtaggcg ccggctttaa cttttttgcg ggcactttgg aaaaagctcc
     5641 tgaatggatg gaaaaagcta gtctagagtg gttatttaga ctggtaaagg aacctcgtag
     5701 actatggagg cggtatatct tgggaggtat aaagtatatc tactatacta ttgaatctaa
     5761 gtaggggggc aataaaaata gatgaaaata cttatagtag ttacaatgac gaataacttt
     5821 ggtaagaagg ggtcctataa ttctcaggaa ataggattag ctcgagggtt agctgaatta
     5881 ggccacgaag ttattgtata taaaagtgta aaaagtgatg aggaagttgg aacagagcaa
     5941 ttaagcaata cggcgatgat tcactatatc aagtgtcgtt atgtaggatc aaatggattc
     6001 ttatcaacaa agaattttga taagaatgcg gatgttctaa tacaatttgc ggaccttcaa
     6061 ctatcagtac ctcatgtata ctcatggact gtaaaaaatg gaataaaata tataccttat
     6121 aatgggataa cgcgaagtca aagtggcaat aaatatataa agacaattat tgaaatattg
     6181 gcgcatcgaa attataaaat ttataagaaa aatgggtgtg ttgccaaaaa tgatcgagtt
     6241 tctgaaaaat tagtacaatt aggagtaaat aaagtgaaac ttgctcctgt ttgtgtggat
     6301 tttgaacagt tacataagaa ttacgaagca atagatttta ctactctcag agaaaaatgg
     6361 aatattcctc gcgatgttcg tgttatttta tatgtaggac ggtttgaaaa ggataaaaga
     6421 ccgttagata tgattagttt atttaataaa cttgatgagc ataattattt gctgatggta
     6481 ggaactggtg ctttactcga gcaaacgaag cagcagataa atttacttgg actgcagaat
     6541 agagtaaaaa taattgagcg tattcctaac aaagatattt gggagttata ttgcttatcg
     6601 gatgtatttg taaatctaaa ctatactgaa atttggggta tggttttgct agaggcaatg
     6661 tactatcgcc tcggaattat tgctgttaat gcacctggcc cacagaatat tattttggat
     6721 aatagatatg gaatgttggc taaatctgac gatgaaattt tgacattctt aaaagacgga
     6781 cgatttacca acgatatcat agatgcagca tatcagcgtg taactacaga atttagatgg
     6841 tcaaagtcgg gagaaattat gcttagcatg ttggaaggtg ataaatgata tggaagtaac
     6901 gaaattaatg gcattgagga atcgatatgc tttaaacata gttgataatt gcacgagaaa
     6961 aatagccaaa attcttggtt gttgtattgg taaaggtgca cagataggga actctgttga
     7021 atttgttcat aattctgtag gcactgtgat tcattctgac acaatccttg aagatggtgt
     7081 taaagtttat cagaatgtga cgtgtggttg agcagatagt aatgaacgta tcatcattcg
     7141 agtaaaaaag aacgctgttt tatgtgtggg tgctaaaatt ctttgtaaat ctaacacaga
     7201 attatgcgtt ggggaaggtg ctgtagttgc tgcaaataca gtggtattga ggtctattcc
     7261 accctacgaa gtgtgggggg tacctgctaa aaagatgggg agataaaaca tgaatgcata
     7321 taaattatac aaagtagaac gatggtttta cttacacaaa atggagtttt ttgccaagat
     7381 tgtaaaggca ctaatttatg tacttcataa tagctcaatt tcatatcaaa cagaaattgg
     7441 agataattgt aagttcttat acggtggcat aggttgtgta attggaaaag atacaaaaat
     7501 aggtaatcac gttataatcg gaacgaatgt actgactggt ggtagatcca ataagcctgg
     7561 tatgcctaca attggaaaca atgtatatat cgctactggc gcaaaaattt taggtaatat
     7621 cacaataggg gacaatgtaa tagtaggggc taatgctgtg gtcattaatg atgttgaacc
     7681 taattgttcg gtaggaggcg ttccggctag agtattgaaa aaagatattg atgtaaatga
     7741 ttattgtagt ttgaatcgtt actaaaagga gagattgtat gttgtatttt gttattcctt
     7801 taatgagtgc gaaggcagca aacaattggg agatggttag taccttattt aaccgaacat
     7861 tatggtcgtg ttataatcag actgatcctg atttcaaaat cattgttgct tgccatgaaa
     7921 ttcctaaact cacgcatgaa tatgatgaca gagttgaatt tattcaagtt agcgaaaagg
     7981 atgcccctat tcccacaaat caagacgaaa aaatgattga taagggttat aaaacacatg
     8041 ctctcgcaat gcgtttgcga gagttgggcg gcggtttcgc tatgatggtt gacgcagatg
     8101 atcttgtaag ttctcatttg gcggaatatg tgaattccca tccccaggaa aatggatttt
     8161 atgtcaaaac gggatacgtg tact
//
LOCUS       DAFEKH010000090         8066 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.093, whole genome shotgun sequence.
ACCESSION   DAFEKH010000090
VERSION     DAFEKH010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8066
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.093"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..882
                     /locus_tag="LP386_002697"
     CDS             <1..882
                     /locus_tag="LP386_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HBL1919880.1"
                     /translation="ISVPVALFSFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTY
                     NDYFQIGMIGMIVSLVVVLTVANISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVL
                     GVVLLDLQIILGFILAGIWALLFTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMT
                     LAMFNNSAAYASPYFSAIFGDWIPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILA
                     VVLAVNPTMSPAFLFPLFAITTIAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGW
                     IIGAILCLITFLLYGNA"
     gene            930..3059
                     /locus_tag="LP386_002698"
     CDS             930..3059
                     /locus_tag="LP386_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HBL1919881.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKNLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKAIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPHTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            3034..3723
                     /locus_tag="LP386_002699"
     CDS             3034..3723
                     /locus_tag="LP386_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919882.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKEIE
                     KRCTEYDLDYK"
     gene            complement(4131..4817)
                     /locus_tag="LP386_002700"
     CDS             complement(4131..4817)
                     /locus_tag="LP386_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL1919883.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(4953..5147)
                     /locus_tag="LP386_002701"
     CDS             complement(4953..5147)
                     /locus_tag="LP386_002701"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919884.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(5197..5637)
                     /locus_tag="LP386_002702"
     CDS             complement(5197..5637)
                     /locus_tag="LP386_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HBL1919885.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELEQLFQAYASLDDVNS"
     gene            complement(5641..6486)
                     /locus_tag="LP386_002703"
     CDS             complement(5641..6486)
                     /locus_tag="LP386_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HBL1919886.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVDWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLVANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAVYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            6635..8053
                     /gene="pepV"
                     /locus_tag="LP386_002704"
     CDS             6635..8053
                     /gene="pepV"
                     /locus_tag="LP386_002704"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HBL1919887.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
BASE COUNT         2481 a         1515 c         1713 g         2357 t
ORIGIN      
        1 atttcagtac cggttgcact gttctcattt atgggctcga ttatggctgg aatctttgct
       61 aatatcgtca atttcaaaca atatcaaacg atttatgctg gtttcaatcc agcggctgaa
      121 agctatactt ataatgacta tttccaaatt ggtatgattg ggatgattgt aagcttagtt
      181 gtggtactaa cggtcgctaa tatatcaatg aacaaaaaga aacgctatgc aatggcagca
      241 aacgtaccag ctgaaggtgg cgacgcacca atgatctcat ggttagccgt attattacca
      301 gttttagggg tcgttctttt agatcttcaa atcatcttag gttttattct agcaggtatc
      361 tgggcattgc tgtttactgg aaaattgcgc ggaggttata aagaaatctg tcgtcagttt
      421 gcgaaattat ttacagatgg cgcagtcgat gttgcaccaa tggttggttt cttgatgacc
      481 ttagcgatgt tcaataattc agctgcgtat gcttctcctt atttttcagc tatttttgga
      541 gattggatac cgcaatcacc attagtcttg gcaatcgtat ttgctatatt gacaccacta
      601 ggatttttcc gcggtccaat gaatctagtc ggttcaggct cagctatttt agctgtcgtg
      661 ttagctgtta atccaacgat gtcgccagcc tttttgttcc cgttatttgc aattacaacg
      721 attgctcctc agcatttaga tattacacaa tcttgggttg cttggggatt aggttataca
      781 aaagtaactt ctcgagaata tatgaagaaa tccatcccaa ctggttggat catcggtgcg
      841 atcttatgcc tgatcacgtt cttattgtac gggaacgcct agtaaacaaa acgtcgataa
      901 aaacgattag ataaatggag gaaaagaaaa tgaaacgttt tgtgcgaatg ggaattgatg
      961 ttggcggtac acatacgaaa gcagtcgcaa tcgataatgc gacgcacgaa atcatcggaa
     1021 aatcttcagt gaaaacaacc cacgatgatg tccgtggagt agctgcaggt gtcgttcagt
     1081 cttttcaaaa ttgtttgcgg gaaaataata tcagtccaga agatgttgtg tttgttgcac
     1141 attctaccac acaagcgact aatgcactga ttgaaggaga cgtagcaaaa gtcggcgtaa
     1201 tcgggatggc aaaaggtgga ttagaaggtt ttttagcaaa acgacaaact agattgaacg
     1261 atatcgattt agggaataag aaaaaaatag agattgtcaa tgcattctta cctgtcaaaa
     1321 acttaaatgt agaccgtgtt tcagaaacga tttcttcttt agaaagagaa agagcggagg
     1381 tcttggtttc ttctatggca tttggagtag ataatgggga accagaacga gttgtttatg
     1441 aagcagcatc tgtgaaagcg atccctacaa cgatggcttc tgacatcaca aaattatatg
     1501 gattgacaag aagaactcgg acagcagcaa tcaacgcatc tattttacca aaaatgctag
     1561 atacggcaac ctcgacagaa gactccgtac gagaagcagg ggtcaatgtt tctttgatga
     1621 ttatgcgcgg agacggcgga gtaatggaaa tcaatgaaat gaaaaaacga cctgttttaa
     1681 ccatgctttc cggtcctgct gcatcagtca tgggctcttt gatgtacttg agagcgtcta
     1741 atggtgttta ttttgaagta ggcggaacaa caaccaatat cggggtcatt aaaaatggac
     1801 gtccagcaat cgattattca attgtaggtg gccacccaac atatatctct tcattagatg
     1861 ttcgggttct aggtgtggca ggcggttcga tggtacgggc taatcagtca ggaatcatcg
     1921 atgtcggtcc acgttctgca catattgccg gtctagatta tgcagtattt acggagacag
     1981 aaaaaatcaa aggtcctaag gttgaatttt tctctcctaa agaaggagac cctgctgatt
     2041 acgtcaaggt agtgatggaa gacggagaag aagtgactat tacaaataca tgtgcagcca
     2101 atgttcttgg attagtgcaa gaagaacatt tttcttatgg aaatgtccca tctgcacgaa
     2161 aagccataca ggcattagca gactattgtc atacgacggt tgaagacatc gcagagcaga
     2221 tcatggaaaa atcctatgct aagattgaac cggtgatttt agaattggca gacaagtatc
     2281 acttggagaa agatcagatt tctcttgtag gtgtaggggg cggcgctgcc tcattgatta
     2341 cttactttag taataaaatg ggtgtgaaat attcgattcc tgaaaacgcc gaagtgattt
     2401 cttctattgg tgtagcactt gcaatggtcc gagatgttgt agaacgtatc atcccttcgc
     2461 caagtaaaga agatatacga tcgttgaaaa atgaagcgat gaataaagcg attgaatcag
     2521 gcgctacacc agaatcgatc gaagtccacg tagaaatcga tccacatact tcaaaagtaa
     2581 cggctatcgc tactggttct acggaagtga aagcaaccga tctaaccaag gagatcacaa
     2641 cagaagaagc actagagctt gctgcagagg atatgcgatt aaataaaaat gaagtttgct
     2701 tattggaaaa tacacctttc ttttatgtat gcggcgaaca gaatcgttca aaaaatgctg
     2761 gaagtcttcg gatcatcgat caaaaaggat ttatcaaggt ccaacgtgga catgcttcat
     2821 gtatgaaaac aactgcagcc aattatatga cagctgtcga acaactttgg gaagatatgg
     2881 cagtttatca aactgaattg attgcccgac cagaatttta tctctgctta ggagcaagag
     2941 tctctgattt tacagcgacg gatctggaac aactacagct tttgatggat ctggaagtat
     3001 ctactatgga accggaggaa gaagtgatcg tcgttgccgg aaatatcaaa caaacataag
     3061 ttagaagagt tactaaacga attacaacag atccccgaag aaatttgggg attctaccag
     3121 tttcggcgag atttattttg gaaaaagatt cctttgtcca agcagaaaat tcttatacaa
     3181 caatcaatcg attgtggtat cgaaacggca tgtagcatca aaaaaaagta cccttttgcc
     3241 gatgtaggag aaatctgtga acaaatggct gttccaatcg tttcctgtga atcagagcaa
     3301 ataaacgaac gaatcacttt tgcaacttat gcagaagatg aagggatccg attgatgacg
     3361 gagccgttag aaaaattaaa atgttcagga ctagcttcga tctctaaaga aacagcgcaa
     3421 gctttgatta ttggacatga actatttcac cacatcgaag cttctgttaa gggaatttat
     3481 acgcaaagcg aaaaaattgt gctgtggcgg ttgccttttt atacacatca atcaaacatt
     3541 cgtgcattga gcgagatagc agcgatgagt ttttcaaaag agatgaatca aagcgatttt
     3601 tcgccttatg tattagaggc agtcttactt tggccatata atgaaattcg tagccaaggg
     3661 atcttagaag aaataaaaga aatagaaaaa agatgtacgg agtatgattt agattacaaa
     3721 taaagagact gtgacaaaag tcgtgtcaca gtcctttttt tccgaataaa cggtgttctc
     3781 ctgtcaactc ctcggtcaca agtcaaaata ttcaacaaac atgagaagct gttttttgaa
     3841 attgttcctt gtgactcgga gatgaacggc aggctcacga cctcttggaa aaaggtgttc
     3901 aaaagcttgc atctgcggta ataagaacag ccaagttaaa aacataagaa gctattttta
     3961 cttggctgtt cttattactt gatgcagggc agctttttca caacctctca ataaacggtg
     4021 tgcaatcagc tgaccctcgg tattagctca aaaaaaacgg caaaatatga ggaactattt
     4081 tgccgtttat ttctctaata ctcaggtcaa aacgctgatt ccaaaacctc ttatttgatg
     4141 ggtctgtcct gaatatcttc aaaataatcg gggtaattat gaatcacgta ttcttgctcc
     4201 tcgataatca tatgtaaatg catcgtgcaa agaaatccga cttcatcaaa gttatgatca
     4261 atcattgatt gaagcattgt ctgatgttca tctaatactc gaccccagtc taattctgaa
     4321 atcgtcaaac gtaaccatct gaaacggttc aagtgcgtac tataactttc tagccaatcc
     4381 caaatttctc gttttccagc aatttcataa caagttcggt gaaaatcagt atccaaatca
     4441 aaaaaagctt ttttattttg agcgatcact gcctgatcgg tttgttctag tattttttct
     4501 agtttagctt gatcttgctt ggtcattttc gcactgcatt cttgcaggat cggtttttcc
     4561 aacttttccc gcgtataacg ggctaatgaa gcagatcgga tatcgatttt tgaaacataa
     4621 gtgccggact gtggaatggt ttttacaagc tcttgattgc gcagttggat cagtgcttct
     4681 cgaatcggtg tacgcccgat agctagttgt tcttctaaca ctttatcgga gattttactt
     4741 ccgggtgcta actcggaata aatgatttgt ttacgtatag attcataagc ttgctgttgc
     4801 aaattattga taaccattta accttccttt ctatgcagat ataatctatt ataacataaa
     4861 tcgcttacaa atcgtgtggg cataaaaaca cagtctgcaa aaaaagccct gataggcatg
     4921 cctattagag cctcgaaaag aaaaatattg aatcaatctg gtcgtacctc ttggatcggt
     4981 ttgacacgac cgccgattct tttagcaaaa gcttcggatt cttttttgtc tttgaaaatg
     5041 agcagattgt ctaagttttt ttcccgagtg cgacagccag ttttatcgat gtaaccgtgc
     5101 attactttaa cgacatacat ggggatcacc tgcttttttc ttttcattat acgaactact
     5161 cgacacaata caagaaaaat gcttagacgg tctttattaa gaatttacat catccaaaga
     5221 agcgtacgct tggaataact gttctaactc cggattgact ttgctcagct tcactaatcg
     5281 ttgcgaatca gaaagtaaaa aacagtgttt actactgcca gtagttttta attttttgtc
     5341 ttcagttccc acaatttcgt agctaaaatc caaccgtgtt cccgtatact tttggatagt
     5401 tgggtggatg ctcacttttt ctccgtaatg gatcatttct ttatagctgc aatttacttc
     5461 cagaacgggg atgatgatcc cagattcttc gattttttta tagggaaacc ctagatgtac
     5521 caataaggct acccgagcct cttcaaacca gcggatataa ttgctgtgat gaataatccc
     5581 catttgatct gtttcataat aaaaaggttc tcgcacataa cctgtaaatt tctccatgac
     5641 tcatgcctcg ttttccattg attttttaca aaaataattc atccacttcg gaagtgcttc
     5701 gctgatttgt gtcggcaaaa caatatattg ttcttttgcc agctggtctc caatgaaact
     5761 atgaagataa acagctgctg caatcgtttg gtcattttga ggaaactggg ctaaaaatcc
     5821 tgtgatcatc ccagctaaag tgtcacccat gccgcctgtt gccatagcag cagaacctaa
     5881 aggattggtg tagaagtgct ggtgaccata aatttttgtc tcatgacttt tcaaaacgag
     5941 cacagcaccg atttcctgtt gcttcttttt gttttcttta tcccgttgtt cttgtatcgg
     6001 tagagaactc aaccgttgcc actccatttg atgaggtgta agtacagttt gttcgggata
     6061 gggtagcaaa agatgattag caacaagtaa acttaaagca gagccatcaa tcaccagcca
     6121 ttgttctttt gattggtttt ctagtacttg tttgaaacgt tccaaactct tagaagaagt
     6181 acccaatccg ggaccaatca agagtacatc tgcttgcttt attacggaaa gaaactggtc
     6241 agtatccgtc caatctacaa tcattgcttc tggcagatga ctgtgaagag cactccgatt
     6301 tttttcatca gttactacag tcgtgagacc cgctccactg tgtacggcag ctaaagcact
     6361 cataatgatt gctccgccat attgttcatt gccgccaatc aaaacgatac gtccaaatgt
     6421 tcctttatgt gaaatctttg gacgaggtgt gatgactctt ttcactagtt gttcgtttat
     6481 cagcatcgaa aaacctcctt ttactcatta tagcgtatat tttttttaga gaaaaacaga
     6541 taagaaaagg aattgtcaga ttttttgaac tatttttttc tgtaatttgt ggtatcatga
     6601 acacgaagac ttaaataagt ggaggattaa ctttatgaca attgattggc aaaaagaagt
     6661 agaagcacgt aaagaagact tgcttgaaga cttgaaaaat cttttacgtg tcaacagcga
     6721 gcgcgatgat tcaaaagtaa caccagatgc accatttgga cctggacctc gcgacgcatt
     6781 gaaacatatg ttagcttatg gcgaacgtga tggatttaaa gtaaaaaatg tcgataacta
     6841 tgcagggcat attgatcttg gcgaaggaga cgaaacgcta gggatatttg gacacatgga
     6901 tgtcgttcct gcaggagatg gctgggacac agatccttat gaaccagtaa tcaaggatgg
     6961 aaagatcttt gcacgcggat caagcgatga caaaggtcca agtatggcag cttactatgc
     7021 gatgaagatc attaaagaac ttgacttgaa actatcaaaa aaagttcgct tcgtagtcgg
     7081 cagcgatgaa gaaagcggct ggggcgatat ggcttattat ttcgaacatg aagaagaacc
     7141 agattttggt ttctcaccag atgctgaatt cccaatcatc aatggtgaaa aaggaaatgt
     7201 ttctttagct ttacgcttca aaggcgacaa tgcaggagat tatgtcttga aatcttttgt
     7261 ttccggactt cgcgaaaata tggtgccagg aacagcaact gcagcacttc aagtaccaag
     7321 tgcagatgca gctatcgcga tggaagaagc attttaccaa ttcatcgaag caaatccagt
     7381 aagcggaacg attgaagcgg acaatacgta tgtaaaaatc gaattagttg gtaaaggcgc
     7441 acatggtgca agcccacaat ctggtatcaa tgcaggttct ttcttggcat tgttcttaga
     7501 taactatgaa ttcctaggat ctgctaaaca atttatccat gtagcagctg cttatgtcca
     7561 tgaagatttt tatggagaaa aactaggagt cgcttatgaa gatgaaaaaa tgggcaaatt
     7621 gacaatgaat gctggactat ttgcttttga agaaaatggt acagaggaag cgaacttcat
     7681 caatatgaat ttccgttttc caaaaggtgt aacagtagac ggattgcaaa gtgacatcga
     7741 acaaacagtg gggcaagaag gcgcaacagt tactcgaggt gctcgcgtaa tggaaccaca
     7801 ttacgtacca atggatgatc cattggtggc tacattattg caagtctatg aagaccacac
     7861 tggagaaaaa ggctacgaac aaatcatcgg tggcggaact tacggacgtt tgttgaaacg
     7921 tggcgttgct tatggagcga tgttcccagg atatactgat acaatgcatc aagcaaacga
     7981 atttatgagt cttgatgact tgttcagagc aacagcaatc tatgcagatg ccatctatcg
     8041 tttggcgaaa taaaaatact aaaaaa
//
LOCUS       DAFEKH010000091         7702 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.094, whole genome shotgun sequence.
ACCESSION   DAFEKH010000091
VERSION     DAFEKH010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7702
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.094"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..224)
                     /locus_tag="LP386_002705"
     CDS             complement(<1..224)
                     /locus_tag="LP386_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBL1919888.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFYSWK"
     gene            370..453
                     /locus_tag="LP386_002706"
     CDS             370..453
                     /locus_tag="LP386_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HBL1919889.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            578..1315
                     /gene="erm(B)"
                     /locus_tag="LP386_002707"
     CDS             578..1315
                     /gene="erm(B)"
                     /locus_tag="LP386_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBL1919890.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            1485..1745
                     /locus_tag="LP386_002708"
                     /pseudo
     CDS             1485..1745
                     /locus_tag="LP386_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            1908..2573
                     /locus_tag="LP386_002709"
                     /pseudo
     CDS             1908..2573
                     /locus_tag="LP386_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            2609..2854
                     /locus_tag="LP386_002710"
     CDS             2609..2854
                     /locus_tag="LP386_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBL1919891.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            2957..3826
                     /locus_tag="LP386_002711"
     CDS             2957..3826
                     /locus_tag="LP386_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HBL1919892.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            3807..4541
                     /locus_tag="LP386_002712"
     CDS             3807..4541
                     /locus_tag="LP386_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL1919893.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            4574..5486
                     /gene="ant(6)"
                     /locus_tag="LP386_002713"
                     /pseudo
     CDS             4574..5486
                     /gene="ant(6)"
                     /locus_tag="LP386_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
     gene            5483..6025
                     /gene="sat4"
                     /locus_tag="LP386_002714"
     CDS             5483..6025
                     /gene="sat4"
                     /locus_tag="LP386_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HBL1919894.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            6118..6912
                     /locus_tag="LP386_002715"
                     /note="aph(3')-IIIa"
     CDS             6118..6912
                     /locus_tag="LP386_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HBL1919895.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            7188..>7702
                     /locus_tag="LP386_002716"
     CDS             7188..>7702
                     /locus_tag="LP386_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBL1919896.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMI"
BASE COUNT         2685 a         1177 c         1595 g         2245 t
ORIGIN      
        1 attttccatg aataaaagga ttttttattt ttctttttcc aaatttgata gagtagtttg
       61 ccatattctt gcacccaacg ataaatcgtc gtatgagaaa cgttaatgcc acgatcatat
      121 aagatttctt gaacttcacg atagctaagg ttataacgaa gatagtagcc cacggctaca
      181 ataatcacat cctgctgaaa ttgctttcct ttaaaatgat tcatcgtcat tcctcctgct
      241 atctttttct attattctac cttatttgat agtagattta aaactttgca acagaaccat
      301 tttgtgtata ataggaattg aagttaaatt agatgctaaa aatttgtaat taagaaggag
      361 ggattcgtca tgttggtatt ccaaatgcgt aatgtagata aaacatctac tgttttgaaa
      421 cagactaaaa acagtgatta cgcagataaa taaatacgtt agattaattc ctaccagtga
      481 ctaatcttat gactttttaa acagataact aaaattacaa acaaatcgtt taacttctgt
      541 atttatttac agatgtaata acttcaggag tgattacatg aacaaaaata taaaatattc
      601 tcaaaacttt ttaacgagtg aaaaagtact caaccaaata ataaaacaat tgaatttaaa
      661 agaaaccgat accgtttacg aaattggaac aggtaaaggg catttaacga cgaaactggc
      721 taaaataagt aaacaggtaa cgtctattga attagacagt catctattca acttatcgtc
      781 agaaaaatta aaactgaaca ttcgtgtcac tttaattcac caagatattc tacagtttca
      841 attccctaac aaacagaggt ataaaattgt tgggagtatt ccttaccatt taagcacaca
      901 aattattaaa aaagtggttt ttgaaagcca tgcgtctgac atctatctga ttgttgaaga
      961 aggattctac aagcgtacct tggatattca ccgaacacta gggttgctct tgcacactca
     1021 agtctcgatt cagcaattgc ttaagctgcc agcggaatgc tttcatccta aaccaaaagt
     1081 aaacagtgtc ttaataaaac ttacccgcca taccacagat gttccagata aatattggaa
     1141 gctatatacg tactttgttt caaaatgggt caatcgagaa tatcgtcaac tgtttactaa
     1201 aaatcagttt catcaagcaa tgaaacacgc caaagtaaac aatttaagta ccgttactta
     1261 tgagcaagta ttgtctattt ttaatagtta tctattattt aacgggagga aataattcta
     1321 tgagtcgctt ttttaaattt ggaaagttac acgttactaa agggaatgga gataaattat
     1381 tagatatact actgacagct tccaagaagc taaagaggtc cctagcgcct acggggaatt
     1441 tgtatcgata aggggtacaa attcccacta agcgctcggg accccttgta ggaaaatgtc
     1501 ctaagtgtgg caacaatatt gtattaaaaa aatcgtttta tggttgttca aattatcctg
     1561 aatgtaagtt tactttagct gaacatttta gaaagaaaaa actaaccaaa acgaatgtaa
     1621 aagaattact ggagggaaaa gaaaccctgg taaaaggaat caaaaacaaa gagaaaaagc
     1681 cctacaatgc cgttgtaaaa attggggaaa agggatatat tgattttatc tctttttcaa
     1741 aataaacatg gggctgaccc aaaagtagct cctatatgaa aaatagaggt ctttccattt
     1801 agatagtagt ggaaagacct ctatttatct tttgaaagtg aatacaaaaa taaagcacac
     1861 tctgctataa tataggtgat taatccattt gagagaggtg ctttatcatg tatcaaaatt
     1921 ataccataaa ccaactttgt ttgcctatag atcttgaaat taaattagaa gaaaatgatt
     1981 ttgctcatgc cattgtgcag tttgttgact ctattcccga tgaagtcttt cttccttatt
     2041 atcaatctat gggtagaccc caatatcatc ctcgtatgct actttccatt attctttgtg
     2101 cctatattca aggggtttat tcgggccgcc aaatacaaaa tatgctgata gatagtattc
     2161 ggatgcgcta cttatctcaa gagcaattcc ctaactttcg tactattaat cgttttcgcg
     2221 ttcatccgat tatgaacgat attctagatc attcatttgt tcaatttcgt gagctactgg
     2281 ttcaaagtgg cttaatcagt ggcagtgctc tatacattga tggtacaaaa attgaagcgg
     2341 atgcgaataa atactctttc gtttggaaaa aaagtatttt aaagtataag gatagccttg
     2401 atcaaaaagc ccttgaaaac taccaacaaa tggtggaaac aaaaatctta cctgagttaa
     2461 tagatgattt aaaggatgaa ctttctatag aagagattga aaggattcgt caatctttgg
     2521 aagaaaagga aaatcaatta attgaagcga ttgaccaaac cgaaacagta gaagggggct
     2581 gacccattat taataaggag tggacaacat gattgatgta aatgagctat tggaagaagc
     2641 tattagagaa actgaaaatc taaatgatgg cgaagttttt cttgttaaag atttattcaa
     2701 gggatatgtg gggaatagga tacccagaaa ggatcgactt ctgcttggaa cgttattttt
     2761 aaaccatgtt agcaaaatga atggtaattt aaaggctatt gaaaagactt catctaatca
     2821 gcagaggtat aaaaagacaa ttgataagtt ttaactatct tttgtgaaat taaaaaaatt
     2881 ataaatatgt tgagtagaag caaaagattt ggcttggaat ttttacagca gtgaatcgat
     2941 aaaaggagca tgcttgatgg tagataatat tattaaatca gtagcagaga aattatcctc
     3001 tctgtcttat atagaaggta ttgttttagg tggttcacgt gcaaggggca cccatacaga
     3061 ggattcggat atagatatcg gcatctatta caattcagaa tcatttgaca taaatactat
     3121 taatcaattc gctacaaagc tggatgatga gcatagaaat aaccttgttg tacctcccgg
     3181 agcatggggt gattggatta atggcggcgg atggttagtc ataaacgggt atcatgtgga
     3241 tttaatttta cgtgatatta aacgtgtgga acaaataatg aaagatacag agcacggaat
     3301 tgttactgcc aattatcaga ctgggcatcc ccatggttat attagtgcaa tgtatcgagg
     3361 agaattagcg attagcaaaa tactatatgc taagaatgaa agcttatgcg aattaaaaaa
     3421 acaggcagaa acttatccca atgctttgca gaaaagttta gttaactttt ttatgtttga
     3481 agcagggttc tctttaatgt ttgtaaaagc aaattcggga acagacgata aatattatat
     3541 tgcgggtcat gtttttcgta tagtttcatg tttaaatcaa gtgttatttg catgtaataa
     3601 tgcttattgt atcaacgaaa agaaagctat aaaactgctt gaaacttttg aacataaacc
     3661 tgaaaaatat accgagaagg taaatcatat ttttgaagta ctcggtatct cactttttga
     3721 atgctacgac atgaccgaga agctttataa tgaagtgaat gaaattgtat cggagataaa
     3781 taacttttta aacgaggaga gttcagatga aagaaaacaa atatgatgat aatatatttt
     3841 ttcaaaaata cagtcaaatg agtcgctcgc agaaaggact ggctggtgcg ggagaatggg
     3901 agactttgaa aaagatgcta cctgatttta agggtaagcg tgtgcttgat ttaggatgcg
     3961 gctatggatg gcactgtata tatgcgatgg aaaacggtgc ttcctctgta gtaggtgttg
     4021 atatttctca taaaatgctc gaagtagcaa aaggaaaaac ccattttcca cagattgaat
     4081 atgaatgctg tgccatagaa gatgtggatt tcccagagga gagctttgat gtaatactaa
     4141 gttcgcttgc gtttcattat gtagcagact atgagaattt aataaaaaag atatatagga
     4201 tgctgaaggc tggtggcaat ttagttttta cagttgaaca tcctgttttt actgctcatg
     4261 gaacacaaga ctggtattat aacgaaaaag gagaaatact gcatttcccg gtggacaatt
     4321 attattatga gggcaaacgg acagctatgt ttttggaaga aaaggttaca aaatatcata
     4381 gaacactgac cacatatcta aatacactgc tttcaaatag ttttataata aatcagattg
     4441 tggagccaca gccgccagag aacatgatgg atattccggg gatggcggat gaaatgcgac
     4501 gcccaatgat gctgattgta tcggcaaaaa agaagatgta ataatataga aaaaataaac
     4561 gaggagtatg taaatgagat cagaaaaaga aatgatggat ttagtacttt ctttagcaga
     4621 acaggatgaa cgaacgtatt cgaattgtga cccttgaggg gtcacgcgca aatattaata
     4681 tacctaaaga tgaatttcag gattatgata ttacatattt tgtaagtgat atagaaccgt
     4741 ttatatctaa tgatgactgg cttaatcaat ttgggaatat aataatgatg caaaagccgg
     4801 aggatatgga attattccca cctgaagaaa agggattttc ctatcttatg ctatttgatg
     4861 attacaataa aattgatctt accttattgc ccttggaaga gttagataat tacctaaagg
     4921 gcgataaatt aataaaggtt ctaattgata aagattgtag aattaaaagg gacatagttc
     4981 cgactgatat agattatcat gtaagaaagc caagcgcaag ggagtatgat gattgctgca
     5041 atgaattttg gaatgtaaca ccttatgtta ttaaaggatt gtgccgtaag gaaattttat
     5101 ttgctattga tcattttaat cagattgttc gccatgagct gctgagaatg atatcatgga
     5161 aggtcggcat cgaaacaggc tttaaattaa gtgtaggcaa gaactataag tttattgaaa
     5221 ggtatatatc cgaggatttg tgggagaaac ttttgtccac ctaccggatg gattcctatg
     5281 aaaacatatg ggaagcatta tttctatgcc atcaattgtt cagggcggta tccggtgagg
     5341 tggcggaaag gcttcattat gcctatccgg agtatgatag gaatataaca aaatatacca
     5401 gggacatgta taaaaaatac actggtaaaa ccggctgcct ggatagcaca tatgccgctg
     5461 atatagaaga gaggcgggaa cagtgattac agaaatgaaa gcagggcacc tgaaagatat
     5521 cgataaaccc agcgaaccat ttgaggtgat aggtaagatt ataccgaggt atgaaaacga
     5581 gaattggacc tttacagaat tactctatga agcgccatat ttaaaaagct accaagacga
     5641 agaggatgaa gaggatgagg aggcagattg ccttgaatat attgacaata ctgataagat
     5701 aatatatctt tactaccaag acgataaatg cgtcggaaaa gttaaactgc gaaaaaattg
     5761 gaaccggtac gcttatatag aagatatcgc cgtatgtaag gatttcaggg ggcaaggcat
     5821 aggcagcgcg cttatcaata tatctataga atgggcaaag cataaaaact tgcatggact
     5881 aatgcttgaa acccaggaca ataaccttat agcttgtaaa ttctatcata attgtggttt
     5941 caaaatcggc tccgtcgata ctatgttata cgccaacttt gaaaacaact ttgaaaaagc
     6001 tgttttctgg tatttaaggt tttagaatgc aaggaacagt gaattggagt tcgtcttgtt
     6061 ataattagct tcttggggta tctttaaata ctgtagaaaa gaggaaggaa ataataaatg
     6121 gctaaaatga gaatatcacc ggaattgaaa aaactgatcg aaaaataccg ctgcgtaaaa
     6181 gatacggaag gaatgtctcc tgctaaggta tataagctgg tgggagaaaa tgaaaaccta
     6241 tatttaaaaa tgacggacag ccggtataaa gggaccacct atgatgtgga acgggaaaag
     6301 gacatgatgc tatggctgga aggaaagctg cctgttccaa aggtcctgca ctttgaacgg
     6361 catgatggct ggagcaatct gctcatgagt gaggccgatg gcgtcctttg ctcggaagag
     6421 tatgaagatg aacaaagccc tgaaaagatt atcgagctgt atgcggagtg catcaggctc
     6481 tttcactcca tcgacatatc ggattgtccc tatacgaata gcttagacag ccgcttagcc
     6541 gaattggatt acttactgaa taacgatctg gccgatgtgg attgcgaaaa ctgggaagaa
     6601 gacactccat ttaaagatcc gcgcgagctg tatgattttt taaagacgga aaagcccgaa
     6661 gaggaacttg tcttttccca cggcgacctg ggagacagca acatctttgt gaaagatggc
     6721 aaagtaagtg gctttattga tcttgggaga agcggcaggg cggacaagtg gtatgacatt
     6781 gccttctgcg tccggtcgat cagggaggat atcggggaag aacagtatgt cgagctattt
     6841 tttgacttac tggggatcaa gcctgattgg gagaaaataa aatattatat tttactggat
     6901 gaattgtttt agtacctaga tttagatgtc taaaaagctt taactacaag ctttttagac
     6961 atctaatctt ttctgaagta catccgcaac tgtccatact ctgatgtttt atatcttttc
     7021 taaaagttcg ctagatagag ttctatatta gagatgtaaa gagttttggt gaagaggttt
     7081 gtgagtatgg cttttataac cagggtgcaa tgagaagcac taacagcagc tagcttaaga
     7141 acgcatagga tatacttttt atggaagtca cagaggagga ataaaatttg aacaggatta
     7201 acagagtaac ctctattctt attcagctgc aatcaaaaaa aataattcct gccaaagaaa
     7261 ttgcacagcg atttaatata agcttaagga cagtttacag agatatccgg acacttgaag
     7321 aagccggaat accaattgga tctgaggccg gaaaaggata ttttcttgta gagggcttcc
     7381 tacttccgcc ggtaatgttt acagcggcgg aagtgggtgc attgattaca gcagggaaat
     7441 ttttaaattg ccatggagat gaatcattta taaaggattt tgattcagct atgtataaaa
     7501 tcaaatctat tttgaagcat ggtgaaaaaa actatgcaca ggagttggag aacagtatta
     7561 acgtgtacag cacatctgga cagaaaaata cattggcgga taacgttatt gcagcaattc
     7621 agactgcaat ctgcaataaa agggtaatat caattcaata tcctgcatca ggagggcaag
     7681 aaccggaaag cagaatgata ga
//
LOCUS       DAFEKH010000092         7608 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.095, whole genome shotgun sequence.
ACCESSION   DAFEKH010000092
VERSION     DAFEKH010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7608
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.095"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(37..642)
                     /locus_tag="LP386_002717"
     CDS             complement(37..642)
                     /locus_tag="LP386_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HBL1919897.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVASYGMICSARELHLPNAPEKKGILVLPEDAVVGEVFPK"
     gene            complement(838..1302)
                     /locus_tag="LP386_002718"
     CDS             complement(838..1302)
                     /locus_tag="LP386_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBL1919898.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKALEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKQMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYAIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            complement(1324..1644)
                     /locus_tag="LP386_002719"
     CDS             complement(1324..1644)
                     /locus_tag="LP386_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBL1919899.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VIKG"
     gene            complement(1787..2866)
                     /gene="pepA"
                     /locus_tag="LP386_002720"
     CDS             complement(1787..2866)
                     /gene="pepA"
                     /locus_tag="LP386_002720"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HBL1919900.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            3066..3416
                     /locus_tag="LP386_002721"
     CDS             3066..3416
                     /locus_tag="LP386_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBL1919901.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKTSFLKEGAIEGAWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLDISRKKGAID"
     gene            3601..4554
                     /locus_tag="LP386_002722"
     CDS             3601..4554
                     /locus_tag="LP386_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBL1919902.1"
                     /translation="MESREKIAVLIPCYNEEATISTVIEDFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAAHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVKNTITYLYKTKIRDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMCKDYKPLLFFGIWTIFFFLFGLVMGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYQNKEMK"
     gene            4567..6354
                     /locus_tag="LP386_002723"
     CDS             4567..6354
                     /locus_tag="LP386_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919903.1"
                     /translation="MHKKKENLFPTFFATLFASGFAFFTSYGLGTLNPTVIIGLAMVL
                     LLAFKQYGIELFSIKNKVAAIARLFFSAAFALTLSIGRQIQFQYVSANYTKTTIADGS
                     IFYFLVYFSIFVYSFLFLQSIYLSMPKLETFFTAQNTQAFSSRKYFLFFTVFLVLCWL
                     PYLLALYPGVVLPDSLSSVAQSMGDVPISNHHPVLFTLLVKLFVHDLPTDTINHGVFL
                     FSIFQTLITASAISYSLCWLLKRNIHFFPVLISLCYFAFAPVFPIYALNMQKDTLFSI
                     ACFLFSLAVFDFIFQREKPTILNQIYVIILALLTTYLRNNGIYVVTGTGLICGLIILK
                     QKRYQAFFQVVLGYTVIAGLLIHPLMARYAIPTETAEQLGVPLQQISRTIVMDGDLSK
                     KDKAFMNQLLPIKDYEAYSPSLADSIKWHKNFNNEFLNTHKKEFLSLWARNLPSNIKI
                     YTDAYILETFGFWVPGTKNSYGFLDTRVNTNNYGMKQVDLIEHLTGLSGMKKIIDARD
                     FFGSGTLLWLAIGSALLAIFKKKYRYLLLFLPGMLVFATIMIATPVAFSLRYVFVLAL
                     GLPVYILSPFLLDKREKMKTDIGDTHETI"
     gene            6341..7543
                     /locus_tag="LP386_002724"
     CDS             6341..7543
                     /locus_tag="LP386_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919904.1"
                     /translation="MKLFKKIFFAFVLLIASYCVLLTITFFIPQHSIESNAEKSLQMV
                     EKEGMYPSINQGNMLGTRLDNFTDHLMIRKTKADPELNSLENAMSMADYPRYWHGYQL
                     FLRPLLLGMSLGSIRMIYAAILFLLIGLTSYFLTKCSDIYLTTALLISLAIGNAATFF
                     FSMQFSNIWILTLLSVLLFLTKPQLSNTNQQLFLYFFVIGSLANFFDLLTTPVISWGI
                     PVIIIYYVTNKYLMDKRSSLSKQVGSFVFTGIFWGLGYGLTWVAKWILSSIILNKNIV
                     KDAINQILFRTEGNDKYPLHRLEMLKSNIRLMYPKVAILLLLITCLVFLYFAYRKRNS
                     WRPFQLLVLFVLAAVTPYIWYNILANHSQIHYWFTYRTQIITSFAILSAFAFLIPPEK
                     SKDELNYF"
BASE COUNT         2168 a         1446 c         1366 g         2628 t
ORIGIN      
        1 aaaaagaggt tgtgacaaag acttgtcaca acctctttat tttggaaata cttctccgac
       61 tacggcatcc tcaggcaata ctaagattcc ttttttttct ggagcatttg gcaaatgcaa
      121 ttcacgagca gaacaaatca ttccatagct ggctacccct cgcaaagttc ctggccagat
      181 catcattcca tctggcatca tggctcctgg ttttgcaacg acaacttttt gtccagcttc
      241 gatatttggt gcaccgcaaa caatttgcaa tactgtccca ttgtccactt ctgtctcagt
      301 aatcgataaa tggtcagagt caggatgcgg gacgcatgtt tttacatacc cgacaacgat
      361 cttcggttca tgatcagctt caagctgttc ttcgaatcct gcttctttaa tcaatcgatt
      421 caatttcgct aattcttcat ctgttaagct tacttggccg ttcccttcaa ttgttagatg
      481 atcggagata tggaaaaagt tccaagcaac aacttgacct tgttcatctt tgatccgagc
      541 aacattccat ttacgttcga cagtgttttc tgttccttta tcgtcggcta tgataaccat
      601 caaagtgtct ccgacgtgtg ctttgttata agcaaaaatc atgttctttc ctccattatc
      661 ctttgctgag atttatctta acaaaaaatt gcattcactg catgagattt ttttcatgct
      721 ttatttccga agaagcttct tctggaacac catttattcg taacaaggga ctgtgacaag
      781 acttttgtca cagtcccttt actgtttgat taaaaaggtt atacaagttc cacttgctta
      841 attactcggc tgttcttctt cgtcagaaac gatcaagaca tcacaaggtg aatgacgtat
      901 gacgtagctg gctacacttc ctgtcataaa gcgttcgact gcatttagtc cagactgccc
      961 aaccatgatt agatcgattg catatttttt tggcaatttg actgccatgg attcacgaac
     1021 agagccgtat gcaataattc cttctatatt tgtgtaatca acagattttc catattcttt
     1081 acattcttcg atcatttgct tggctgtttc agtttgctga tcgactagat tttgatcaat
     1141 aggagcatag cccataaaat tataaaattg ctgatcgatt acgtttgcta catatacttt
     1201 cccattatta cggcgagcca cttctaacgc ttttttgaaa gcagcaagtg cttgttcact
     1261 accgtcaata cctactaaaa tgttcttata ttcttgattc atcttgaccc ctcctaacag
     1321 atgtcagcct tttattacac tttctaggaa cgattcgatt tcctgttttg ttttacgatc
     1381 tttattcact agacgaccta attcttttcc gtcttggatc acgacaaaac ttgggatacc
     1441 aaaaatgttc cattcagcgg ctacatctat gtacttgtca cggtctactt caataaattg
     1501 ccaatcagaa aagtcatttt cgatttcagg catttgcggt ttgataaaac ggcagtctcc
     1561 gcaccagccg gcagtaaaga aaaatacact ttttccagtt tctacgtagc ctgctaattc
     1621 ttctaaacta tttgggataa tcattctttt tcctctactt tctgtttatg tatttttcaa
     1681 ttaaattata cacctttctt tcgaactaac aaacattgat cctcttttta taaaaaaaat
     1741 ctgacaaaag gttgcttttg ccagatttta tagtttcact atcgcgttat ttcccgtata
     1801 cgatcgtgtt cactgttgat ttatctaaac ctttcaatgt ttgaatcaac atttctcgtg
     1861 cagcttcaaa atcgcgaata ctgaacatcg tttgatgcgt atggatataa cgtcccacta
     1921 cgccaatcac tgtacttggg attccttcat tttgtgtatg agcagcacct gcatctgtac
     1981 cgccttttga aacaaagtat tgataaggga tgttgtttgt ttcagcgata tctagcaagt
     2041 actcacgcaa acgaggaagc atgatcaaac ctggatcttg gatacgcatc aatgtacctt
     2101 ctcctaaatg tccgaatgtg ccatttttcg tcactgtgtc atctgctgca gagcagtcta
     2161 ctgcaaagaa cagatctggc ttgaatttat tgacagaagc tttagaacca cgcaagccta
     2221 cttcttcttg gacattcgcg cctgcaatca atgtatgacc taatgtttca ttttgtaacg
     2281 cttctaaagc ttctaatacc attgtacagc catagcggtt gtcccacgat ttgctgatga
     2341 tattcttccc gttggctgtt ttgatcgttt cagcgtaagg aacgattgtg tctcctggaa
     2401 gaacaccgta actcattgcc tcttctcttg attcaaaccc agcatcgaac aaaatatctg
     2461 ttacttctac tgatttttgt ccgcttgttc ctcgtaataa atgtggggga acggaagaag
     2521 aaatacatgg ataattctta ccagtagagg ttttaagtgt aaaacgttga gcagaaacaa
     2581 cgtaagggtt ccatccgcct agaggtacga ctttaaaaag cccgttttct tggatttgtg
     2641 tcagcatgaa tccgacttca tccatatgtg ctgcgaccat tacacgaggt gcatccgctt
     2701 cttcatggtg gcgcagccca aaaatgccgc ccaaaccatc taactgtaac tcatctacca
     2761 gcggttccat atgactttcc atataggcgc gaacgtcttg ttcaaaaccg cttgttcctt
     2821 gtaattctgt taactctttg attcgttgaa atgttttttc ttccatatgc tattcgtcta
     2881 aatttcagac taaactcctc tcagacttat attgatctgc ggataaaata tgattttttc
     2941 tgcagaccga tcgtatttat tatagcttat tttttctggt agcggttatt tatttcaaag
     3001 aaaatatgag agtgtggtaa aataaacaca aagagtagca agtgagaaga aggaggtata
     3061 tccacatgta tgaagaaagc gaattaagct attttaaagg cgggttagcc gttgggatcg
     3121 gtctaggatt attgagtggg gtagcttcaa cgatttggta tcatcgcaaa aaagtgttat
     3181 cagcagacca agtgcttgaa aatatcaaaa catctttttt aaaagaaggc gcaatcgaag
     3241 gtgcttggat ctcttttgaa aaagaaccta ttcggaaatt cgccgttcgg tcgagtgctt
     3301 atcggggtgg gctttcccgg atagaagatg gcgaaactgt ttattatgaa tttttagcag
     3361 atgctcatac aggaaccgta ttagacattt caagaaaaaa gggcgcaata gattaatacg
     3421 tcaaaaaaat gaaataacga atacgcaccc actatctaaa agagaggtat cctatccttc
     3481 ttttatagtg ggtgattttt ataaaaatag ggctatttcc tcttggaata gctagtattt
     3541 gtagttatta tacggtattc ttgaaataag attagtttta ttatataagg agagtgacaa
     3601 atggaatcac gtgaaaaaat tgccgtgctc attccttgtt ataacgaaga ggcgacaatt
     3661 tcaactgtta ttgaagattt taaaagggaa ttaccagaag cagatattta tgtctatgat
     3721 aataattcga ccgatcgaac atacgaattg gccgttcaag gcggagcaat cgtaaagaaa
     3781 gaaccacgtc aaggaaaagg gaatgtaatc cgtcaaatgt tttttgatat tgatgccgat
     3841 tattatttga tggtagatgg tgatgatact tatcctgcag aagctgcaca tggtttgctt
     3901 gagaaattac gttctggcga agcagatatg gtcattggcg atcgtctatc aaatggaacc
     3961 tattttgatg aaaataagcg tcctttccat gattttggga ataatctggt taaaaataca
     4021 attacttact tatataaaac aaaaattcgc gatgtcatga ccggctatcg aggattcaat
     4081 cgaatttttg tcaaaagctt ccctattatg agttctggtt ttcaaatcga aacagaattg
     4141 acgattcatg ctttagataa aaaattcaag ttcgttgaga ttccaatcga ttatcgcgat
     4201 cgtcctgaag gtagcgaatc aaaattgaat acattctctg acggattcaa agtgatcatg
     4261 atgatcatca aaatgtgcaa agattataaa cctttgcttt tctttgggat ctggaccatc
     4321 ttcttctttt tatttggatt ggtcatgggg attcctgtga ttcgtgaata tatgctgaca
     4381 agctttatta cacgcatccc ttctgcgatt ttaagtactg gattgatgac tttagccctt
     4441 ctttcattag taacagggtt gattttggat acggtcgtca caaatgccaa gaaagaatat
     4501 gaattgaatt tataccatgt ctaccacgaa tatcaaaata aagaaatgaa gtaggaggcc
     4561 ttttttatgc ataagaaaaa ggagaatcta tttcctactt tttttgcaac tttatttgcg
     4621 tcaggttttg ctttttttac ttcttatggt ctaggaactt tgaatccaac agtaatcatt
     4681 ggtttagcca tggttttgct acttgctttt aagcaatatg gaatagagtt gttttcaata
     4741 aaaaacaaag ttgcagctat tgcccgattg tttttttctg cagcttttgc tcttacactt
     4801 tctattggca gacagataca atttcagtat gtctcagcaa actatacaaa gacaacgatt
     4861 gctgatggaa gtatttttta ctttcttgtt tatttctcca tttttgtgta ttctttttta
     4921 tttttacaat cgatttattt atcaatgcca aaactggaaa cattttttac tgctcaaaac
     4981 acacaggctt tctcttcaag aaaatatttt ttattcttta ctgtcttttt agttctgtgt
     5041 tggcttcctt atctgttggc attgtatcct ggagtggttt tgcctgattc gttaagttcg
     5101 gtcgcccaat ctatgggtga tgttcctata agcaatcatc atccagtctt attcacctta
     5161 ctggtcaagc tatttgttca tgatttacca actgatacga tcaatcacgg tgtattttta
     5221 ttttcgattt ttcaaacatt gataacagct tcagcgataa gttattctct ttgctggctg
     5281 ttaaaaagaa acatccattt ttttccggta ctcattagtt tatgctattt tgcatttgca
     5341 ccggtttttc caatctacgc cttgaacatg caaaaagata ctttgttctc tatcgcttgc
     5401 tttttatttt ccttagcggt ttttgacttt atttttcaac gagaaaagcc aacgattctc
     5461 aatcagattt acgtaatcat ccttgcttta ctgaccacct atctaagaaa taatgggatt
     5521 tatgtagtaa ccggcacagg tttgatttgc ggcttgatta ttttgaaaca aaaaaggtat
     5581 caagcattct ttcaagtggt gctgggttat acagtgattg ctggactact catccacccg
     5641 ttgatggctc gttatgctat tcctacagaa actgctgaac aattaggtgt tcctttgcag
     5701 caaatttcta gaactattgt tatggatggt gacttgtcta agaaagataa agcattcatg
     5761 aatcagctac tcccgataaa agattatgaa gcgtattctc ctagtcttgc agactcaatc
     5821 aagtggcata aaaattttaa caatgagttt ttgaatacac ataaaaaaga atttctatca
     5881 ctatgggcaa gaaatttacc aagtaatata aaaatctata cagatgctta tattttagaa
     5941 acgttcgggt tctgggtacc tggtacaaaa aatagttacg gctttttaga tactcgtgta
     6001 aacacgaata attatggtat gaagcaagta gatttgattg aacatcttac tggattgtca
     6061 ggaatgaaaa aaatcatcga tgctcgtgat ttctttggtt ccggcacatt actgtggtta
     6121 gctatcggca gtgcactttt agcaatcttt aagaaaaaat atcggtattt actccttttt
     6181 cttcccggta tgcttgtttt tgctactatt atgattgcta ctcctgtggc ttttagttta
     6241 cggtatgtgt ttgttttagc attaggtcta cctgtttata tcctctctcc ttttttacta
     6301 gataaaagag aaaaaatgaa aacagatata ggagatactc atgaaactat ttaaaaagat
     6361 attttttgct tttgttctct tgatcgctag ctattgcgta ctactgacaa ttactttttt
     6421 cattccgcag cactctattg aatcgaatgc agaaaaatct ctacagatgg ttgaaaaaga
     6481 aggaatgtat ccttctatca atcaaggaaa tatgctaggc actcggttag ataattttac
     6541 tgatcatttg atgatacgaa aaacaaaagc agatcctgaa ttgaactcct tggagaacgc
     6601 gatgtctatg gcggattatc cccgttattg gcatggttat cagctttttt tacgaccttt
     6661 actgctaggg atgagtttgg ggagtattcg aatgatttac gcagccattc tttttctgct
     6721 gattggattg acgagctact ttttaaccaa gtgtagcgac atctatttaa cgacagcctt
     6781 gttgatttcg cttgctatag gaaatgctgc aacctttttc ttcagtatgc aattttcaaa
     6841 tatttggatt ttgactttat tgtctgtatt actattttta acaaaaccac aactctccaa
     6901 caccaaccaa caattattct tgtatttctt tgtcattggt tctttagcta acttttttga
     6961 cttgttgaca acaccggtca tctcttgggg gatacctgtg atcattattt attatgtaac
     7021 aaataagtat ttaatggata aacgcagttc attgagcaaa caagtaggca gttttgtttt
     7081 taccggtatc ttttggggat taggctatgg tttgacatgg gtggctaaat ggatcctatc
     7141 atcgatcata ttgaacaaaa acattgtaaa agatgcaatc aaccaaatcc tctttcgaac
     7201 ggaaggaaac gacaaatacc cgttgcatcg attagagatg ctgaaaagca atattagatt
     7261 gatgtatcca aaagtagcaa tattattgct attgattact tgtcttgttt ttctctattt
     7321 tgcttatcgt aaacgaaata gctggcgtcc gttccaactt ctagttttgt ttgttttagc
     7381 tgctgtaacg ccgtatattt ggtacaatat tttagctaat cactcacaga ttcattattg
     7441 gtttacgtat cgtacgcaaa tcatcacaag ttttgctata cttagtgctt tcgccttttt
     7501 gatccctcct gagaaatcaa aagacgaact aaattacttt taagaatacc gatgtactaa
     7561 ttcattttta aacataaaaa ctccagctgt cagagatagc cggagttt
//
LOCUS       DAFEKH010000093         7597 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.096, whole genome shotgun sequence.
ACCESSION   DAFEKH010000093
VERSION     DAFEKH010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7597
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.096"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(941..1354)
                     /locus_tag="LP386_002725"
     CDS             complement(941..1354)
                     /locus_tag="LP386_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HBL1919905.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1810..2295)
                     /locus_tag="LP386_002726"
     CDS             complement(1810..2295)
                     /locus_tag="LP386_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919906.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2434..2679)
                     /locus_tag="LP386_002727"
     CDS             complement(2434..2679)
                     /locus_tag="LP386_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HBL1919907.1"
                     /translation="MFYHLRKENSNENLDAIALTLLIVGGLNWLLVGLFELDLVAMIA
                     GGSTTIFAKIIYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2872..3672
                     /locus_tag="LP386_002728"
     CDS             2872..3672
                     /locus_tag="LP386_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL1919908.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3691..5559
                     /locus_tag="LP386_002729"
     CDS             3691..5559
                     /locus_tag="LP386_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBL1919909.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRSYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELCDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5552..6043
                     /locus_tag="LP386_002730"
     CDS             5552..6043
                     /locus_tag="LP386_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HBL1919910.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6031..6585
                     /gene="srlA"
                     /locus_tag="LP386_002731"
     CDS             6031..6585
                     /gene="srlA"
                     /locus_tag="LP386_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBL1919911.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6603..>7597
                     /locus_tag="LP386_002732"
     CDS             6603..>7597
                     /locus_tag="LP386_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBL1919912.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVPTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2706 a         1214 c         1443 g         2234 t
ORIGIN      
        1 tgttactatg aataacataa taagaaagta aagtggattg atttgagatc tttttatact
       61 tcaaaaaaga taacacccaa ctttcaaaaa tatgttttgg aagttgggac aaacgagtta
      121 atacatttta atacattatt ttttattcaa aaaaaatagc acaatggcaa agatcgtaag
      181 agagatcata agccccaatg aatgactaaa aagaaaagca gaatcacatg ccatatcatc
      241 ccatatttct tcaagaaaat aaataagcgg gaaaaaggga aggaatagta gaacatcgat
      301 ccagcaccat ttttttcttc ttttgaaata acataaaaca ataaacatga acgtgcaggg
      361 aagtaaaaac aaagctttac tcataactaa caaaatacca gctcctttta tttttttctc
      421 ccccacattc aaagagtaac aatggtatgt acttaataat agaaaaatgg atcaacttgt
      481 atgaataaca gctgaaaaga tctgcaccaa ataaaaaact tccagccaaa actgactgga
      541 agtttatttt tttctgaaat attctaacac aaatatgaaa aagatggccg aagctaataa
      601 gccgatttcg tagcaaaaca atgagatacc agagtcgtaa taataaaatc ctctaatctt
      661 atggataaaa tagatcatcg gacaagcaga taagagtaag tatttgttag gccttttgaa
      721 taagtaaaag aaagcactgg tcattatgat aaatggtatc caaaacaaaa gtttacttaa
      781 gacaatcaaa tgatcaactc ccatattttt taccaagaga gatcataaca tctttatcgt
      841 aaaaacaaaa tatttttttg ctcattttga aaatttaaac atactcgttc ttatccaaat
      901 atataaaaat cgcccctcat tcatcgagag gcgataagtt ctaatttaac tcaatttttt
      961 ttgtttcttt tggctgataa gctgttttag gtaataccaa tttcagcaca ccgtttttaa
     1021 aggttccagt gattttttct tcatcaacat taggaagata gaatgaacgt ttgtaagaga
     1081 ccgaatgtct ttctttccgt acatagttgc catcttcttt atcttctgta tgggactcat
     1141 gattggcgga gatcgtcaaa gtattatctg aatattcaac tgtcgtgtct tctttgtcac
     1201 agccaggcat atcagcagtt agtttgtatt ctttttcatt ttcgactaaa tctacttttg
     1261 gataacttga aacacctaaa aaatcattga atgctggact aaacacgtca ttgaaatcag
     1321 ggaacatgtc gcgaatgcta ggtacatttg ccatttttga tcatcctttc aataagtatt
     1381 ttttatttat ccctatttac gtaataactc tattttgaaa aaaatgcaag tataatggtt
     1441 agctttgtga atatttcatc taatacgata caaaggctat ctttctaatt tgaaaaaggg
     1501 atcattaaaa taataagaag aaaatatgtc aaaaggtaaa aaagtaaatt cttctatcca
     1561 aatatagaaa aattgaatct agaaaaccgc ccgacaataa atttcattaa ctcagttgac
     1621 cgaaaatgaa gtagatacca aaaatttatc aagagagcaa gtagagaagt gagtatattc
     1681 ataagagaaa tagctgtaac gaattattag gttaatgcaa atgcttattt atactccgta
     1741 taactttctc agaaaaaatg ataccaataa tgacttgcta gtactgtaaa tccgtataat
     1801 atcatctaat caaaatggtg ttccatttgc atctgtcatc gtaatcgatc cttcgggtga
     1861 cactcgataa aaaccaacgc ttccagatcc tccttgggaa cggatttgtt tgctggaagc
     1921 tgtgaacaaa taatctcgat caattttttg ataaaagcta ataacaatat cgtcactttg
     1981 taattcggaa cggtgggcaa taagaaatag aagtgctttg tcagagtttt ctaatggaag
     2041 agaaggtaca gtgctttctt gcatttcaga tgttgaagaa atgctaaacg actgaatact
     2101 tgattggcta tgttgcgaat ctacattacc agtagaagta ttagtaatgg aagtagtaga
     2161 agtactttta gttgaaccaa cctcagttgt tgaaatggct gctgaagatt ctttaacaga
     2221 attctttgtt ttatatccac aggcagaaaa aagtattaca gttcccaaca agcctgcgta
     2281 aatcccttta tgcatgatag ctcctcctaa aatagattat ctttattcag tatatcactt
     2341 aaacaaagaa aagcagatgg tttaaaatga aaaaaccttc ccaataaagg gaaggttcat
     2401 gaagataata acttttttaa taattatagc tttctaatat ctttcatcaa cttttctagt
     2461 aatcattggg aaaaatttca agcagtagat cgcacaaata cctacgacga tataaatgat
     2521 cttcgcaaaa atagttgttg aaccaccagc aatcatagct actaaatcaa gttcgaacaa
     2581 gcctaccaac agccagttca accctcccac aatcaataaa gttaatgcaa tagcatctaa
     2641 gttttcatta gaattctcct ttcttaaatg ataaaacaat tatatatcaa aaagagaaac
     2701 attgcttata taacgctcag gaattttagc aatctatgca aaaagatgaa aatttttttt
     2761 gctcttccat tagtacacat tttttagctg aagctgtaaa tttcatgtct taattttttt
     2821 tagtgagctt ttatactgga tttgtaagaa aaaagaagga gaggatcaca tatgtcggat
     2881 tggttggata ttgcaggaaa agtagtaatt gtaactggag gttcctcagg aattggaaga
     2941 agtatcgtcg aaaatttgtt gaagcagaat gcacaagtag cgaattttga tgtaactgaa
     3001 tgccgtatac agcatgaaaa cctactatct ttaaaagtcg atgtgtcttc taaaacggac
     3061 atagaagaag ggatatataa agtaatgaaa catttcaaga cgatcgatgg tctagtcaat
     3121 aatgcaggaa taaatattcc ttctcttcta atagatagaa atcatccaaa aagcaagtat
     3181 gaattatcag aacaagtttt tgataagatg atcgctgtca atcaaaaaag tgtatatttg
     3241 atgagccaag cagttggaag aatcttggtg caaaagggat caggagtgat cgtgaatctt
     3301 tcttctgaat caggattgga aggatcagaa ggacagagct gttatgctgc tacaaaagca
     3361 gcgatgaaca gttttactcg ttcttgggca aaagagttag gaaagaggaa tgttcgtgtg
     3421 gtaggtgttg caccagggat actggaagaa accggtttga gaacacaaga atatgaagaa
     3481 gctctttctt atacgagagg tataagcgtc gaacagctga gaaacggtta cagtcgaaca
     3541 agtacgatcc ctctaggaag gagtggtaag ctgcaagaag tggcggatct agtctgctat
     3601 tatctttcag aaagatcaag ttatatcact ggagtcacga ctaatatttc aggaggtaaa
     3661 acaagaggat aaaggatagg ggggacgcac gtgacgctag taaacagatg gtaccaatta
     3721 ttgaaattac tagtcactca caagaaagtt tcaatccagg aagtgcaaaa agaaatcaaa
     3781 accagtaatc aaaccataaa aaaagatatt ggggagttga atgaagaaat tgccggtatt
     3841 gcaaaaatca tccaaaaaaa caaacatttt gaacttgaaa tttatgattt tgattttttt
     3901 gatgagatca tgcaaggaaa attgaaaaca gccagtgatt tcaattcggc atccaaaaga
     3961 atcgcttatt tactaaatag gctgatcgaa acagaggatt tcttacgtat ggatgatttg
     4021 tctgaagaag tcggtgtcag cagaggaaca gtggtcaagg atctaaagac attaaaagag
     4081 atgatcaatg attttgatgt aaagattaca ggcacaccaa ataaaggact aagaataata
     4141 ggagatgagc tagaattacg actactttta ttttattttg tttctcccta cttttcagag
     4201 acgaaaacag aacagtttct agaagaaaaa caagcaatca aacattttca gaagaagacg
     4261 aatgctagta aacaagaaat caccctttta acgaaagtta tcggtatttc tttgaataga
     4321 atctctagta actatctgtt gaagaagccc atcaatcgtt acagtgggtg ttttgaatat
     4381 atccaagaat tcaatgaact gatcaatcag ttggaagaaa tctatgaact aactttgagc
     4441 caatatgaaa aagattttat cagttttcct ttgaacatca tcaacacaag tataacgatg
     4501 ataaggaaag ctaactctga tttgcgctta tatttcgacc ccatgatgat gcgtattcga
     4561 cgattagatc tcattgatct ggatgagtcc ttcttatatc aagagatgaa acagcacctc
     4621 tctttattga taaatcgggt aatttttcgt tatcgattga ctgatttatt ttatggtgag
     4681 atagaaaaaa agtatccttt ttcttaccaa atcgctagcg aatgcataca agcattagaa
     4741 gctatcttgc aacataagat ctctaaagta gagatcagct acctaacgtt gtatttggag
     4801 ttagcatttc gatatcaaaa agagcatttt tcctctaaaa aagtagccat tgttcatacg
     4861 acaggaaaag gaacagcatt aatgatccaa agacaaatca aaaggatatt ggggagggat
     4921 atacaaataa cacatgtttc agaagaacaa tatgaaaaag tagatctaaa caaatatttc
     4981 gctgttttta caacgattcc gttaaaaaat gtaaatgaag agacaccggt gatccatttg
     5041 actaatcttt ttgatgactc ttggttaagg gcacaatggc aaaaagcaaa aaaaaagcga
     5101 ttagccgggt ttcattctac tgtttttttc tatcaaatat ggaaagaaaa aaagacgtat
     5161 caagaatatt taaacaaatt agtcgctcct ttgatcagaa gctattatgt ggatgaagaa
     5221 tttgaaaaaa ggatcttgaa aagagaatat cagcaaagca catttgttaa caaagaattt
     5281 gcttttcctc acacaaccaa ccagctatct caacacattg ttttatcagt agggctaata
     5341 actgatcaag gtttagcaga aacaggagga aatggagtta tttttttatt tgccatacct
     5401 gaagaaatga cggctgaagt tgagaatgaa ttatttgagc tatgcgatat cctatttgaa
     5461 ctcataaaaa tgggaataga tgagtttatt gaattagcac cgacacaaga atcattttta
     5521 aaactaatca aaagtaaagg agagagactt catgaatgat atgtatctat tcatagtttt
     5581 cgcagcttca gcttatgtgc tgcaagcagt tatcagttgg aagcaactaa agcatttcaa
     5641 tcaaacatat agcgaactgc gaagaaaagg aaaagtagcg attggtaaac gacctgggaa
     5701 aatccgttca ggcacgattg ttatgctagc tatagacgat catgatcaag ttttagaagt
     5761 cagaaaaatg caaggggtta catctttggc aaaatttcat tcattacctg tctatgcggg
     5821 tgaagatatc cattacatcg atcgttacca tccctcagtt cgagcggaag atcgtttgac
     5881 acaagcagct ttagaaaatg ccagagaagt atacttacga atagaggcag gaaatgaaaa
     5941 aagtgaacaa ccttcattgc cttttattgc tatgctcaat aattttcgga tatggaaaag
     6001 tacgatcaaa gaaaaaagga gtgacaaacg atggatatca taacaaaatt tgctgaggga
     6061 tttatgaggc tgttccaaac aggtgcagaa acattcataa gctggatgac aggaatcgta
     6121 ccagttgtct tgatgctgat ggttgcaatg aatacgctga ttgctttttt aggtgaagac
     6181 cgagtaacga aagtagccaa attatcagcg aaaaatccgc ttactcgtta ccttgtgtta
     6241 ccgttcttat ctgcttttat gttgggaaat cctatgtcat ttacaatggc tcgtttcctt
     6301 ccagaatact acaaaccaag ctattatgct gctcaagctc aattttgtca tacgagcaat
     6361 ggtgtattcc cccatattaa tcctggagaa ttgtttgtat ggatggggat tgctcaaggg
     6421 atcgaaacct tagggctaaa ttcgatggag ctggctatcc gatacttgct tgtgggactg
     6481 ctgatgaact ttattggtgg ttggataact gattttacta ctggatttgt atgcagacag
     6541 caaggaatcg ttcttagcaa aaaagtagag ctttcagttg attagagaaa ggagagtttt
     6601 aaatgtatgg tgatattaag atcgtaagag gaaacggcgg gtatggaggt cctttgatta
     6661 ttaggccgac aaaagataaa cacaagttca tctatgtcac aggtggaggt gagaggccaa
     6721 tgatcgtaga taaaatagaa gaactgacag gtatggagtc tatcaatggg ttcaaaacat
     6781 caatacctga tagtgaaatc gcgcttgcaa tcgttgactg tggagggact cttagatgtg
     6841 gaatttatcc taaaaaaggg ataccaacca tcaatatcgt tcccacagga aaaagtggcc
     6901 cattagcaca atatatcact gaagatattt atgtttcagc agtagggtta gaacaaatac
     6961 agccactaat ggaaactgat gataacaaag aaacagtaaa tactgcatct ccagataaaa
     7021 agtacaaata tgatacttct aaaaagataa ccgagcaaaa agcagagcag caaaactgga
     7081 tagcaaaaat tggaatgggc gcgggaaaag tagttgctac attcaatcaa tcagcaagag
     7141 aagcagtaga tacgatgatc cggacagtga tcccttttat ggctttcgtt tcccttttga
     7201 ttggtgtgat acaaggttct gggatcggta atgtatttgc taacattatg gcacctttag
     7261 caggaaatgc agttggatta acaatcattg gctttatttg ttcactgcca tttttatctc
     7321 ctttgcttgg tccaggggca gttattagcc aagtgattgg aacattgatc ggtgtagaga
     7381 ttgggaaagg aaatattcct ccccaattag cattaccggc actatttgct atcaatactc
     7441 aaaatgcatg tgattttatt ccagtcggtc taggtttgga agaagcaaaa gctgagacag
     7501 tagaagtagg tgtaccatca gttctttatt caagatttct taacggcatc ccacgagtta
     7561 tcattgcttg ggtagcaagt tttggattat atagctg
//
LOCUS       DAFEKH010000094         7295 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.097, whole genome shotgun sequence.
ACCESSION   DAFEKH010000094
VERSION     DAFEKH010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7295
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.097"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            1..1259
                     /locus_tag="LP386_002733"
                     /pseudo
     CDS             1..1259
                     /locus_tag="LP386_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
     gene            1252..1599
                     /locus_tag="LP386_002734"
     CDS             1252..1599
                     /locus_tag="LP386_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919913.1"
                     /translation="MIEYNDRGRLKWVGFYLSDHTERINSDNVQRANHNSAKEQMTTE
                     EIAKVLKTAVIKNRPVCIQKEERNAEGYYPDDIVGKIIGSDELGVFVEEEKVHYDEIR
                     NVSFAELVKWSQI"
     gene            3027..3794
                     /locus_tag="LP386_002735"
     CDS             3027..3794
                     /locus_tag="LP386_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HBL1919914.1"
                     /translation="MRDRILEVNQEMVNKLTNISGNYEKYDGTLLDNYIFHDTQNIRI
                     GRSKPRAFILIKEKYLNEWNSTYEMVMTDNFEKVLNFRNALLGSDIGNSSLESIEIEN
                     KTENEGEGLIKNVLKIEQKYISEDRSFYRVTSSVGLANFATNLIGNNASESLLVMCLN
                     TKNEVIAYSEVFKGGINQSVAIPREIFQLALLNNSAKIAVSHNHPSGYEFPSENDKSF
                     TTNLKNAGKTIGIELLDHIIVTSKNTSYYSFQENGSL"
     gene            3820..4362
                     /locus_tag="LP386_002736"
     CDS             3820..4362
                     /locus_tag="LP386_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919915.1"
                     /translation="MGERTQALITVKYGNSKTKASVSIHYQWGYGRYMLMDVLNQGIY
                     LINKAYDLRDKSREELAKGIFDRSTGVINFATYESGVSAYDETGFDGRYEPYQETIED
                     VMKFSDNNDGYAHLEMVFDENGYSLDDKTRLRLFDIEGKQIGLNKFCKNGKEFATKDF
                     IKGYRLLLENYGINLEESVK"
     gene            4363..4930
                     /locus_tag="LP386_002737"
                     /pseudo
     CDS             4363..4930
                     /locus_tag="LP386_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320752.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            4942..5190
                     /locus_tag="LP386_002738"
     CDS             4942..5190
                     /locus_tag="LP386_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919916.1"
                     /translation="MEEMDFLDLENLVEFGYTWKGMIGISRSLANAFYERNYAVYVLY
                     DDNTESLVDEEYKLDLENVLYGIEKEDLAKYIFSWLGQ"
     gene            5209..5448
                     /locus_tag="LP386_002739"
     CDS             5209..5448
                     /locus_tag="LP386_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919917.1"
                     /translation="MTKFKSKGMQWCSYYYVGNDEELLRKAQQKGYPDKMLKQIGYYM
                     PEERIEKESCEVLFDSEQLLVLLTQNKLICQFENN"
     gene            5465..6049
                     /locus_tag="LP386_002740"
     CDS             5465..6049
                     /locus_tag="LP386_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919918.1"
                     /translation="MNENKMVLSEYARLRTINWLNGMQSSGAFDGFDEEYMDFESLSN
                     EDIRYYFIEWYFTEPDEEVEDEQELILERQRILFSEQDSKRLYGLYDLQLNGLKAQYV
                     ADSYDDMVEQGADRVVTYSEDDEEEWENYSDDEICFNDGYMPIEITEEEYDKVSDSDE
                     IGMCTVVSGLDIDVQRVEVAYQKMKERIKSKVES"
     gene            6151..6432
                     /locus_tag="LP386_002741"
     CDS             6151..6432
                     /locus_tag="LP386_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HBL1919919.1"
                     /translation="MKVKSPKEKSRIQVGIDKDLKENAEMILEELGLNPTTAITILYK
                     QVVARGEFPVEIKLSEEEKQGIRLQQLTMDMPVDVLDTDEKLEEWFNEA"
     gene            6422..6763
                     /locus_tag="LP386_002742"
     CDS             6422..6763
                     /locus_tag="LP386_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBL1919920.1"
                     /translation="MKPNEIVTVYVAFTDKNGGKRRPILVVSDKEDRVEFFGITSQYE
                     KKSDQIKRVYFPIAEWEKAGLKKQSWIDVWSLKAISKSRENISFKKVGMLSVSDTKKL
                     NSFIERLKRKV"
BASE COUNT         2718 a          986 c         1507 g         2084 t
ORIGIN      
        1 agcgtggaat gtattgaacg aaatttagac ccaatgacta caccgttaat tgtcatgagt
       61 agatcggata acactggttc aggtctgact ctagcttctt cacctactgc aaagaaaaaa
      121 tatcatatca ctaatgttag tagagctaat gatttacctt atccattacc aaaagaactt
      181 tatattgttc cacctcgaat gaacttatat ataaaaaaaa tatggaagtt aatcagattt
      241 ttagaaagta tgtcgcagat gaagatttat tgatttattc gattgatgaa tcaattttaa
      301 aagtgacaaa atccttaaat ttatttacta gttcagaaac aagaagcgag aggagaagag
      361 aattagctaa aataatcaaa gatgagattg agaaagaaac aggactaata gcaacagtcg
      421 gaataggaga caacccatta ttagctaaac tcgcactgga caatgaagcg aagagtagta
      481 aagaatttat agctgagtgg acttatgaga ctgtacctaa aaaaatatgg aaaataaacg
      541 agatgactga cttttggggc attggatcac gcatgaaaaa aagattgaat catatgggaa
      601 ttatgagtat agaagattta gcaaattgga atccctacac aattaaaagt cagttaggtg
      661 taatcggact tcagttatat ttccatgcca atggaattga tcgtacggat attgctattc
      721 cagcagaacc aaccaaagaa aagtcttatg ggaattcaca agttctacca aaagattata
      781 cgaggagaga agaagtagaa ctagtagtca aggagatggc agagcaagta gccattcgaa
      841 ttagacaaca taattgcaaa actggttgtg tacgcttagc aattggtacg tcaattttgg
      901 aagaaaaatc aggtttctcg caccagatga aaataccaat tacagataat acgaaagaat
      961 tacaaaatta ttgtcttttt ttattcaata agttttatga ggggcaggaa gtaagacata
     1021 taggagtaac ttatagcaga ttagtataca cagattccct acaattagat ttatttagtg
     1081 atccaagaaa aaagattgct gaagaaaatt tggataggat tattgataag attagacaaa
     1141 aatatggatt tacagctatt atacgtgctt catctatgtt agaaggtgca agaagtatta
     1201 cgagaagcac tttaatagga ggacacgcag gaggattagg aggtttgcat aatgattgaa
     1261 tacaacgata gaggacgttt aaaatgggta ggattttatt tgtctgatca tactgaaaga
     1321 atcaattcag acaatgtaca acgtgccaat cataactcgg caaaagaaca aatgacgact
     1381 gaagagattg cgaaagtact gaagactgct gtcataaaaa atagacctgt ctgcattcaa
     1441 aaagaggaac gaaacgctga aggctactat ccagatgata tagtaggcaa aattattgga
     1501 agtgacgagc ttggtgtatt tgtggaagaa gaaaaagtac actatgatga aattaggaat
     1561 gtttcttttg cggaattagt aaaatggagt cagatatgaa cattattaag aaatacgaat
     1621 tgggttatgt tacctatgaa gagctaatag aagaaatatg gggatatggt caacaattaa
     1681 ttaattaatc aagtggggat tgattgcttt tgtttctata ttgaatccgg atcaggatat
     1741 catagataca gatattatgt cgttccatat ccatcagaat aagttcttag agattatatt
     1801 ttcagttaat gtataatatc tttttgttat caatgtgata taattacatt actttagtag
     1861 cttgattagt aaatccagca atttttctat tattcctagt atcgcaacta ctagaagtaa
     1921 ttttgctgtt tgattttcta atcaagcttt ttttgcttta ttagaaaacg atatggatta
     1981 gcagaagagt atttattaca gaaaaagaat tagataagat gttaccagaa aagagttcta
     2041 atattgaact ctttttttat gcctaaattt tttctatcaa ttttgctatt caataaataa
     2101 tttaattaaa aaaagttgta ttagtaggag aatctcctaa agctaccgca agccgtccta
     2161 gccatcgcct agcccgacat tgctagatta ttagtgcatc tcgccataaa cattttctaa
     2221 agccaccgca agccgttcta agcatagctt agcccgacat tgctagatta ttagtgcatc
     2281 tcgccataaa cattttctaa agccaccgca agccgttcta agcatagctt agcccgacat
     2341 tgctagatta gtgcatctcg ccataaacat tttctaaagc caccgcaagc cgttctaagc
     2401 atagcttagc ccgacattgc tagattaagt gcatctcgcc ataaacattt tctaaagcca
     2461 ccgcaaaccg tcctagccat cgcctagtcc gattttgctt gatctgttcc atttctgttt
     2521 atttagtggg tcaacaccgt aaccttaaat agccatcgcc tatttaagat tactaggtct
     2581 tctttgaagg taaaaagtct ttcattcttc aagactttta ggctttcaag ctacgcctga
     2641 aagcattgga attcatcgct ctttatttgg ttttgccatt tataattcct tacgcccatt
     2701 atctttctcg cctgtcatac cttgtcagaa gtgtttagag cttatctcat ctttggatta
     2761 atacaagtgg cgtaaatttt tttctaaacg caagcgttac gaaaataatt tacttaaaca
     2821 cttgtattaa tccggcagat aagaacgcat tctaatcact cccgacaagg caagacaggc
     2881 gaaaaagaca aataaatgaa cgaaaggaag aaacataaaa tgcaaaacca aatagcgatg
     2941 aagaaaaaac cacctccctc taaaacaatc caaacaaaaa agaattttga aaaaccaaaa
     3001 atcaaaaaca gaaagaagcg ttcaacatga gagatagaat tttagaagtt aatcaagaaa
     3061 tggtaaacaa gttaacaaat atcagtggga actatgaaaa gtacgatggt actttacttg
     3121 ataactatat ttttcacgat acacaaaata tcagaattgg cagaagtaaa ccgagagcgt
     3181 tcattctcat caaagagaaa tatttgaatg aatggaatag cacctatgaa atggttatga
     3241 ctgataactt tgaaaaggta ttgaatttca gaaatgcttt gttgggttct gatattggaa
     3301 atagcagtct tgaatctatt gaaattgaaa ataagaccga gaatgaaggt gaaggattga
     3361 ttaagaatgt cttgaaaatc gaacaaaaat atatcagtga agatagaagt ttttatagag
     3421 tcacaagctc ggttggtcta gcaaactttg ctactaactt aattggaaac aatgctagtg
     3481 aatctttgct agtgatgtgt ctgaatacaa agaatgaggt cattgcttat agcgaagttt
     3541 tcaaaggtgg aattaatcaa tcagtagcga taccaagaga gatttttcaa ctagctttgc
     3601 taaacaattc agcaaaaatc gcagtatcac ataatcatcc gagcggatat gaatttccaa
     3661 gtgaaaatga caaaagtttt actacgaatt tgaaaaacgc aggaaaaaca attggtattg
     3721 aattgttaga ccatatcatc gtcacaagca aaaacacaag ctattactca tttcaagaaa
     3781 atggttcttt ataaaaatta gagaaaagag gaaaacaaga tgggcgaaag aacacaagcg
     3841 ttaattacag tcaaatatgg taacagcaaa acgaaagcaa gcgtgtcgat tcattatcag
     3901 tgggggtatg gtcgatatat gctgatggac gtattgaatc aaggaattta tttaatcaat
     3961 aaagcatacg acttacgaga taaatcaaga gaagaattag caaaaggaat ctttgataga
     4021 agtacagggg ttatcaattt tgccacctat gaatcaggcg tgagtgctta tgatgaaaca
     4081 ggatttgatg ggcgctatga accttatcaa gaaacgattg aagatgtgat gaagttttct
     4141 gataacaatg atggctatgc tcatttagag atggtgttcg atgaaaatgg atatagtcta
     4201 gatgataaaa ccagattgcg attgtttgat attgagggta aacagatagg actaaacaag
     4261 ttttgtaaga atggaaaaga gtttgctaca aaagatttta ttaagggata cagattgttg
     4321 ctagaaaatt atggaataaa cctagaagag agcgtgaaat aaatgtttca aaaaagaaaa
     4381 gaccaattcc ctaatttaga agtgaaaagt caaaaagtga ttgatggtga aatgattgaa
     4441 ctattccaaa aaaaattatg gaacgataga aactaccgca agttgcaaat actattttca
     4501 aggaaagaga aacacgttta aaggctttgc cgattctgat gaagaattgg caaagaaaat
     4561 cactgattgg cttgttagga gtgaacatgt tgctagagaa gataccgtta gaaaaacgac
     4621 tgatggggca gtcttaacag gtactaaatg tgtttgttgt aatcatgaat ttgtagaaga
     4681 tgaaggttgt taccgaatca atgaagatgg cgattatctt tgccagagtt gccatgataa
     4741 agaattccca tctcaaagaa gttggtttga atatatgcta caagattacg agatggaaac
     4801 agaagatggt gaagaagtaa tttgtaccaa agaagaattg agtaagcgta gcgatgatga
     4861 gattgaagaa tggtgtgtgt ggttagcaga atcagagaat tgtgttgcct actacacaac
     4921 agcagaatag ggggaatcag catggaagaa atggattttc tagatctaga gaatttggtc
     4981 gagtttggtt atacatggaa aggaatgata ggtattagca gaagtcttgc taatgccttt
     5041 tatgaaagaa attatgcagt ctatgtcctt tatgatgaca atacagaaag ccttgttgat
     5101 gaagagtata aattggattt agagaatgtt ttatatggga tagaaaaaga agatttagca
     5161 aaatatattt tttcatggtt gggtcaataa acgaaagagg gtagcaacat gacaaaattc
     5221 aaaagtaaag gtatgcaatg gtgttcttat tattatgttg ggaatgatga agagcttttg
     5281 agaaaagccc aacaaaaagg ttatccagat aagatgttaa aacagattgg ctattacatg
     5341 ccagaagaga gaatagaaaa agaatcttgt gaggttcttt ttgatagtga acagctatta
     5401 gttttgttaa ctcaaaataa attgatttgt caatttgaaa ataattaata tggggtgaag
     5461 aaccatgaat gagaataaga tggtattaag tgaatacgca agattgagaa ccattaattg
     5521 gttgaatggt atgcaaagta gtggcgcttt tgatggattt gatgaagagt atatggactt
     5581 tgaaagttta tcgaatgagg atattagata ttattttatc gaatggtatt ttacagaacc
     5641 agatgaagag gtggaagatg aacaagaatt aattttagaa cgacaaagaa ttttattcag
     5701 tgaacaagat agtaagaggt tgtatggttt atatgacttg caactgaatg gattaaaagc
     5761 gcagtacgtt gctgatagtt acgatgatat ggtagaacag ggggcagata gggttgtcac
     5821 ttattcagaa gatgatgaag aggaatggga aaactattca gatgatgaga tatgctttaa
     5881 tgatgggtat atgcctattg aaatcaccga agaagaatat gataaagtgt ccgatagcga
     5941 tgagattggt atgtgtacgg ttgtaagtgg attggatata gatgtccaaa gagtagaggt
     6001 tgcataccag aagatgaaag aacgtataaa aagtaaagta gaatcttgat ttgattgttt
     6061 gcaaagtagc caattaagag tataatataa tcataaatgc atttaatgga tataataatg
     6121 agtatattat actcaaaaga ggtgaacgga atgaaggtca aaagtccaaa agaaaaaagc
     6181 agaattcaag tcggaataga caaggattta aaagaaaacg cagaaatgat attggaagag
     6241 ttagggttaa atccaacaac agcaatcaca atcctttata agcaagtggt cgctagaggt
     6301 gagtttccag tagagataaa gctaagcgaa gaggaaaagc aaggaatcag attgcaacag
     6361 ctaactatgg atatgccagt tgatgttcta gatacagatg aaaagttaga agagtggttc
     6421 aatgaagcct aatgagatag taacggtcta tgttgcattt acagataaaa atggtggtaa
     6481 aagaagacct attttggtgg ttagtgataa agaagataga gtagaatttt ttggaatcac
     6541 aagtcaatat gagaagaaat cagaccaaat aaagagagtg tattttccta ttgcagaatg
     6601 ggaaaaagca ggtcttaaaa agcaatcatg gattgacgta tggtctttaa aggctatttc
     6661 taaaagccga gagaacatat catttaaaaa ggttggtatg ctatcagtta gtgatacgaa
     6721 aaagctaaat agttttatcg agagattaaa aagaaaagtc taacaaggct tttctttttt
     6781 gtttatatgt atattaagat atacgtttat ataaacgtat ttatgtatat aaaaatacac
     6841 gtaaatatat acgtgattat aaacattaat aaaatattaa gaattgttaa atagtgataa
     6901 atagtaatat acgaattata agatatattt tatgttaaat gtatgtaaat aaataaaatg
     6961 actgacggat gttgaatagt gataaataac aataattcag acggatacag cgagtgaagt
     7021 agcttgctac gaacgaacag gcagaatgaa acggcagttt cattagagca agtcgcttgc
     7081 gacgtagcgt tactgctgat gtaactggca agttacatag agagagtttg cttgcaaacg
     7141 aacgttacct acttgaatag aaataaaaaa taacagatta gtgaattttg aataggagcc
     7201 acaactcaac caaccgcttg cggtgggtga gtcccccgga gggtgcaatc cgaccgaccg
     7261 ctcgctacgc gaccgttcgt tcgtcttttc ctccg
//
LOCUS       DAFEKH010000095         6644 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.098, whole genome shotgun sequence.
ACCESSION   DAFEKH010000095
VERSION     DAFEKH010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6644
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.098"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(1..859)
                     /locus_tag="LP386_002743"
                     /pseudo
     CDS             complement(1..859)
                     /locus_tag="LP386_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            1102..1557
                     /gene="tnpA"
                     /locus_tag="LP386_002744"
     CDS             1102..1557
                     /gene="tnpA"
                     /locus_tag="LP386_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBL1919921.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1822..1920
                     /locus_tag="LP386_002745"
                     /pseudo
     CDS             1822..1920
                     /locus_tag="LP386_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2143..2373)
                     /locus_tag="LP386_002746"
     CDS             complement(2143..2373)
                     /locus_tag="LP386_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HBL1919922.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(2603..3421)
                     /locus_tag="LP386_002747"
     CDS             complement(2603..3421)
                     /locus_tag="LP386_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL1919923.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            3582..4271
                     /locus_tag="LP386_002748"
     CDS             3582..4271
                     /locus_tag="LP386_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBL1919924.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4285..5787
                     /locus_tag="LP386_002749"
     CDS             4285..5787
                     /locus_tag="LP386_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL1919925.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            5800..6276
                     /locus_tag="LP386_002750"
     CDS             5800..6276
                     /locus_tag="LP386_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL1919926.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(6373..6483)
                     /locus_tag="LP386_002751"
                     /pseudo
     CDS             complement(6373..6483)
                     /locus_tag="LP386_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2172 a         1032 c         1204 g         2236 t
ORIGIN      
        1 acttgtcctc gataagaatt gtagcgccgt gatttacgtg tgtatgtcgt tacttttatt
       61 cctagcttct tgatcaggcg ctgaactttc tttttattga tagagaaacc gcggtttctt
      121 agttcattgg tcatccgtaa acagccataa tccttgtgct tctcccgaac tttaagcatt
      181 tccgcttcaa tctcttgatc tggattttta cggtccaatc gtttttgcca gtacataaag
      241 attgccttag ggaactttaa agtttctaga agctcaacta atttaaacgg tcctcggagg
      301 cttgcgatga ttcgtgcgat tgcttcattc gtcgttgttg ggcttcctgt tttcgcagct
      361 tcctcaattc ttttaaaaag gcattttcaa tttgaaggga acggactcgt ttctccaact
      421 cctcgatgcg ttcacgttct ttagacgttg ctttagttgt agattttttc ttatttttgg
      481 gttcattttt cttagacaag ataggtggac atcctttcgt ttttgagagt ccatcgatcc
      541 caccctcacg gaattgacgc atccaactag cgatcaaatt agggttgttc atgttaagtg
      601 tgttggcaac ttcacgatag gacagctcac ttgttagata taactctatc gcatccagct
      661 taaattgaac agaatatttt ttcttttgtc gctttcttac tagaccctct tcaccaaatt
      721 cttgataggc attgatccag cgcttcactt gtgatggagc cttaatggaa tatttctttg
      781 ccagataatc acttccgcct ttaccatcca agtaatcatg aacgatcttt aatttaagtt
      841 caaaagtata cttagccata aaaaataccg acctccaaaa gttagatttt ttggtctaac
      901 ttttgggggt cggtacaaaa cttaaaagtt ttagaccctt ttattttctt aatgacttca
      961 gtcagttttg tgcgtaaagc gtgcgaaaca agaaaaccgc gcgtttctac gcgtggaaga
     1021 agtatcttta gcgataaaaa ctcctttcga tatactagtg agtggctacc aaccgctcat
     1081 cagatcgaaa ggagtttttt catgtcaaat gacgataaaa gtttagcata tactcgttgg
     1141 aattgtaagt atcatattat ttttacacca aaatatcaac gaaaagtaat ctatgggcaa
     1201 ttacgaaaag atcttggaaa aatacttagg aagttgtgcg aaatgaaaga tgtggaaatc
     1261 atagaagcac atgcaatgct agatcatatt cacatgcttg ttcgagtacc accaaaaata
     1321 tgtatatcca gttttatggg gtatctgaaa ggtcgtagtg cggtactaat ccacgagcag
     1381 cacgcaaatc tcaaatataa atacggaaac aaatcctttt ggtcgaagag atactatgtg
     1441 agtacagtcg gattgaatca aaagacaaat gaaaaataca tccgtgaaca agaagctgat
     1501 gatcgcattc gatatattat aagtaaaaga gagtacgtag aaccatttaa aaaataaaga
     1561 gaagtaagtg agtgaagatg agcagttggc ggtcttttaa aaatcccctt ttaaggggca
     1621 gcgagtgtcg accccttcta gggggattaa aaatacaccc gtcctcacgg gtgtatgggt
     1681 tactgataga cttgatttta actggtgtca gaaacttatg tccagaaagg gtgatgaaat
     1741 tttggcaatt tacggctatt caagaattag cacaagcaac caagattaca aaacacaaat
     1801 tcaaacatta gaaaatgctg gcgcagaaat aatcttccta gaaaatcact ggattatcga
     1861 acacctttgg aagtattttt gagttacgta agtattgatg atctgtctaa cttaatttga
     1921 caattaagag tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat
     1981 gaactaataa ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc
     2041 ataaactttt aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca
     2101 taacattgaa gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt
     2161 cttataaaca agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt
     2221 tatagaaaac attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc
     2281 agtaggttcc tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt
     2341 atttaagaga ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta
     2401 cacgtttttc tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc
     2461 aagaaccgta ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa
     2521 taagctatca agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta
     2581 ggtttagcta agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt
     2641 tttctcttaa ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat
     2701 cacaaatata aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa
     2761 tggctgtttg taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta
     2821 tagcaataat ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg
     2881 ttttcccaga taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt
     2941 gggcttgaaa atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat
     3001 tttctaaatc aagactagta tttccactag atcccactcc aaatatatat atgttttttg
     3061 attgagtgat cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg
     3121 aatagagagc ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat
     3181 gttctttttt ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag
     3241 aaaaaccaat tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct
     3301 taatatcact catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga
     3361 cttttttttc agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca
     3421 tacaaactcc tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact
     3481 cctaaatact ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag
     3541 ttgttatcca aaaataataa aaaattggag tgtttaggat aatggataaa aagaggtttt
     3601 tagatcttat ttcaaaaggt ttgattgttt cctgtcaagc attacctggt gaaccatttt
     3661 acaaagagga agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag
     3721 ttggtatacg tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac
     3781 caatgattgg aattattaaa agagattatc caccagaatc tccattcatt actgccacta
     3841 tgagagaagt agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc
     3901 ttagaaatcg acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat
     3961 atcctcatca gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata
     4021 aagcaggaat agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac
     4081 aagatgggcc agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg
     4141 ctgagggaag gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag
     4201 gtattgttgt gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag
     4261 cattaagtta gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc
     4321 atgttaccaa ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta
     4381 acaaatgaga gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt
     4441 ttaagtatta tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca
     4501 attggtattg ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga
     4561 gtagcttatc tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa
     4621 gatgcaacac tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt
     4681 ttacacaatc gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca
     4741 agatttattc cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta
     4801 atttggccac caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt
     4861 agtttaggaa cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac
     4921 cacaccattt accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga
     4981 tcaacaattg ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact
     5041 ggtctgttta cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga
     5101 ttaccagcag catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat
     5161 ggtgggcttt attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt
     5221 gaatatatgt ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga
     5281 ttatcttttt attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt
     5341 ttgatcgact ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa
     5401 ttaattcctt ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc
     5461 aaaaaattta aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa
     5521 gtaataaaca aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt
     5581 ggaaaagaaa atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg
     5641 aatggggaga ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa
     5701 gtgaagggtg gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc
     5761 aatcaaatat taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag
     5821 aaaaaacaag aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta
     5881 aatgatcctg tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt
     5941 tcaaaaattt atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct
     6001 attaatataa aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt
     6061 gaattacaag gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa
     6121 acctcgttgg ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt
     6181 atagttgttt ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt
     6241 gctcatggga attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa
     6301 aataagctaa ataggatatt tgtcaaatga agttggtgaa cagaaagaac tgttttcttt
     6361 ctgttcattt ttttatttta ttagtaatga ttccccatgc caaatcatga tccgtaattt
     6421 aaagttataa aagcttcgaa atccattggc atttcgttgg aataccttga tatgattatt
     6481 caaatataaa atatagagag aagagagaga gggaagatat ttataaaggg caaagttatg
     6541 tttactcaac ttaggaaata gaaatagatc aatttatatt ctcttgtcaa tcgaatatga
     6601 accttagcac tatataccaa atatagtaaa atgctgaaag atgt
//
LOCUS       DAFEKH010000096         6467 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.099, whole genome shotgun sequence.
ACCESSION   DAFEKH010000096
VERSION     DAFEKH010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6467
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.099"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(109..564)
                     /locus_tag="LP386_002752"
     CDS             complement(109..564)
                     /locus_tag="LP386_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919927.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(718..1926)
                     /locus_tag="LP386_002753"
     CDS             complement(718..1926)
                     /locus_tag="LP386_002753"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HBL1919928.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(2038..2370)
                     /locus_tag="LP386_002754"
     CDS             complement(2038..2370)
                     /locus_tag="LP386_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBL1919929.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            2518..3393
                     /locus_tag="LP386_002755"
     CDS             2518..3393
                     /locus_tag="LP386_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL1919930.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(3475..4056)
                     /locus_tag="LP386_002756"
     CDS             complement(3475..4056)
                     /locus_tag="LP386_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HBL1919931.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(4062..5321)
                     /locus_tag="LP386_002757"
     CDS             complement(4062..5321)
                     /locus_tag="LP386_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBL1919932.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(5323..6369)
                     /locus_tag="LP386_002758"
     CDS             complement(5323..6369)
                     /locus_tag="LP386_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919933.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
BASE COUNT         1804 a         1337 c         1102 g         2224 t
ORIGIN      
        1 aaatcttgtc acagtccctt attctgaata aacggtgtgg aagagacagc ctatcagtag
       61 taataagaca catctctttc acagcctcat ttttgcgtaa aaatcgattt attcgaaaaa
      121 ttccccgtat acatcttcta cacgttgatc tggattgatc acgatataca agttacctgt
      181 tttttcgctg atttttgttg attgatattg attgtctaat ccttctgttc ctttatctag
      241 atatgggaag tacacaagat caggtgtgcc atttcggtaa aggatttcca ttcgctcgat
      301 atcttcgtat ttcaatgcgc gattaaacat gcccatttcc agtccgccta ggttgatatc
      361 atgtgtcgca actgcgtccc cttcatggaa gatttcgatt ttaaatccag cacacggatg
      421 gatttcaaca aattcactgc cattgattcg tccaaaactt gttgtgattt gtttgatcca
      481 aagatcgccg atatgacggc ggttgatcgt ccaggtttct ccatttctaa aataaaattt
      541 tagcgctgtc atttctttac tcattaaaaa gactccttta tgatgtaatt tattcttgta
      601 ctacctcagt ttagcacaaa tttatgtaag tggtcacatc ttatgttttt tcttctaatg
      661 acgtatctgc ccactttaag tagccaacaa agctgagcag atacagtcta gtgtttttta
      721 aatcaatttt tctttcgata aaaaatccaa aacctgtttt ttatcatttt ttattctttg
      781 ttctacgacg gctttttcag ctaattgcaa agcttcacta acccacttac caggtttttt
      841 tccagtttct tctagcaaga ttttaccatc tactgctaat tcgcttaatg acttgatagg
      901 taaacgatca taggattctc ctacggcatc catctgaggt gtttcgtcaa aatagatcat
      961 caattcttct acttgcagtg catgtttttt gcctaagaag tacaattcga atggttccaa
     1021 agctccagtt tctcgttgtc gtagtccttg gacaagtgct tgaacgtctt taatcatttg
     1081 gttagaacac ttccacgatt tcaaaaagga acgaatctca ttttctttta gatccagttg
     1141 gctgatcaat aatgcccatg cttggctctc ttctttcaat gggacggatg gtaattcagc
     1201 aaaacgtaaa agtgcttcgc cttcttcttt caaaccggga cagcaaatgt agcactctgt
     1261 ttcaataaat gcatggattc ccgcggcccg ttcatttccc aagagcatct tgatgaattc
     1321 cacatttata cgttctacag atattttacc taatagctcg tggttttctt tgatggcgta
     1381 gaaggtttct tcctctaatt tgaaccctag ttgactgaca aaacgcaacc cgcgcatcat
     1441 tcgtaaggca tcttcatgga accgctcatg aggattgcct acagctcgca agatctgttc
     1501 ttctagatct tgcagaccat cgaacaaatc gatgatttct ccatcttctt tcaaagcaaa
     1561 cgcattgatc gtaaaatctc ttcttttcaa atcttctgcc aacgaacgaa cgaattcgac
     1621 atgatctggt ctacggtagt cctgataagt tgattccgtc cgaaatgtgg tgatctcata
     1681 ttgttcatca ttttctaata ccaacacagt tccatgttcg atcccaatat ctatcgtttt
     1741 tggaaaaagc tgtttgattt cttctggaaa tgcgcttgtt gcgatatcca catcatggat
     1801 tggctggttc agcaagatat cacgaacact tccacctaca aaataagctt catatcctgc
     1861 attctctaat tttttcagaa ctggaattgc cttttggtat tccagaggta attgttttaa
     1921 tttcattttt ccaacctttc ctgcgtgttt cttgtcctga gataaagact cagttgcatg
     1981 gtgactgttt gacaagtccg tttcagagtc ttcaaggcca ggaccacttc atcttgttta
     2041 ctcgtcctta cgctcaaagc gattatggtc tctttgattg aatttttcca tgtttttttc
     2101 aaaaacttca gttaagtcga tattcaatga attagccatg atcatcgtaa cgaataaaac
     2161 atcaccaagt tcttctgcta ccgagttaac tggttcagaa gcctttttgc ttttttctcc
     2221 ataagtgtgg ttgacttctc ttgccaattc acctacttct tcagttaatc gagccatctg
     2281 agctaatgga gagaaatacc ccaccttgaa ttgctggata tattcatcca cttcctgctg
     2341 catactgtat aaagaacgct ttttatccat ctttttccct ccaaaactat cttaccaaaa
     2401 ctttaacgca aatcctagat aagagcaatt gagaaaatcg aatttccatg ctacatttag
     2461 gaaggaattt ctaaatggaa attctgtgaa aatacataat tgaaagctgg aattcatatg
     2521 gtcaaacgaa aaacagtaaa agaagttctt tttatcatta taggaacaag tatttatgca
     2581 tttggtcttg tttacttgaa catcgctaat catttagcag aagggggagt ctcagggatc
     2641 accttgatct taagagcttt atttggtatt gatccagctt atacgacttt attaatcaac
     2701 atcccattga ttttactagg aggaaagatc ctcggtaaac gttccttggc ctatactgtt
     2761 ctaggtacac tttctttgtc attcttttta tggatctggc aaagggttcc actagaaatc
     2821 aatttacagc atgatctact gatcgtttct ctacttgcgg gtttagttgc aggtgtagga
     2881 agcgggatcg tctaccgcat gggtggaaca acaggcggca gtgatattat cgctcggatt
     2941 ttagaacaaa attacggcat cactatgggg cgttccctat tggcatttga tatcatcgtc
     3001 ttacttgctt cattaaccta tatcgacttg aaacgtatga tgtatacgtt gattgtttcg
     3061 tatgttttca gtcgtgtgat tgattcgatc ttagatggcg gatattctgc aaaaggtcta
     3121 cttgtcgtct ccaacaaaag cgaagagatt gcaccactac tgatgaccgg tctgcaaaga
     3181 ggtgtgactt tcctttctgg agaaggcgca ttctctggta attcaaaaaa aatcatctat
     3241 atggtcgtta gctctagtga attaactgaa gctaagagga tcgtccacga gattgacgaa
     3301 aaagctttcc tttcaatcat caatgtgcat gaagtggaag ggcaaggctt tacttatttg
     3361 aagccacaga caagattact gaaaaaacta taagaaaaaa gacaaagata ggctatgagg
     3421 aaagattcca catccagctg acctttgtct tttttagtac tatactattt ttaactaatt
     3481 gttatgttca cttacccggt tacttttctt ttgtgtctgc aaaaggatct ttcggttaac
     3541 ttcatcagat aatttcaaaa aagcatccct atctccatct tctagtgctt gatcgatttg
     3601 agcataaagc atttttagtt ttgcctcttc ttctttttct tgaaaatatc gttcaattaa
     3661 ttcagtatct tcttcactga ctgaagaatc ccaagaagaa aatggattgt cttctaagat
     3721 agatagatat tctcttgtct gccaagcatt ttcgaatata cattccacat ataaaggctt
     3781 tttccaattc aaacggattt catgaaaaat ctggtctgtg tccgtaaatt cttttccctg
     3841 caaaaacaat ttcatgggtt ccccttcaac agatagatca ctgatctgca gtcctcgatc
     3901 cgcaaaattc gccccttcaa caaagtggac attgcttaaa atcgcttcat gattggcaag
     3961 ataattcaag atccaaaaaa cttctcttcg gctaaaagat acatgattga ccatccacgt
     4021 taaaaaattc ttcttttccc gtacatcaat tagcattttt ctcacctctc tgttaggtca
     4081 tctaataatg acagtgcctc catatctcct ggttcaagtg ttaaataata agtcaataat
     4141 tcttgcgctc ttttcagctg cccttcttct cttaagaaaa aggcatactc tttcaagaaa
     4201 tctggttcat gtgatagttc atgataagcc tgttcatagt gtacagctgc aacggtaaag
     4261 tcttctaatt cattataagc atgggctagg ttccattctg cataaggatt agcagtttct
     4321 tccatctgat tgatcacttg tatcacatct tcatatcttt catcatccaa gtaaagatta
     4381 cttaaagtaa gtaatgtttc atcttgtttg tctcctactt ctaaagcttt cagtaaaagt
     4441 tcttctgctc gctgtctatc atgcagacgg aaagcatttt ccgaggccag gtgataaagt
     4501 tcgacttggt aaggattttc tttgattcct tcttctaaca ctgtttgtgc ttcttcaatc
     4561 atttcttctt cttgaagagc ttgtcctaga tatagatata acgattgata atgcggatta
     4621 acttctcgaa gttcttccag atagttgatt gcctgctgat tttctttcaa ttgaagattc
     4681 gtaaaagcta gctggaacag tcgatcatct gtcctttctt ctttcagtgc ttcttctaaa
     4741 ggtacgatag ctgcttcgaa ttctccttgc atacttaagg attgtcctaa acgttcctgc
     4801 atcgagattc ctgaaatttc atttatcccg cttgccaaca atgtttcata aaccactgct
     4861 gcctctttga aacgatcaac tgaaaaatac aattcagcta gcgcaaactg gatcaatggt
     4921 tcatcaggaa gcaacccagc tgcttctttc aattttgctt cactcacttc agggattccg
     4981 ataacttggt acaaatcagc tatcgccaat aagctttgcg gatagtaatc actttgctta
     5041 tccacttttt ccaggtattc aaaagctaag tcgatctcat tatcttcgat tgcaatttct
     5101 gctaacggga tgttcagtcc gtcattttct gggtattggt tgatcagttg ttcaaaaatc
     5161 tgttttgctt cgatcaaaaa gccaatagcc agcaattctt cgcctagttc agctaatata
     5221 tctgctgggt cttcttttaa tgctttttct aaaaagattt gtgcttgtga caagtcttca
     5281 tctgataaag cttgcaacat tttttcgcta tttgtattca tttcaattcc ctcttatctc
     5341 actgacgatt tgttgaaata ccgtcattgt tctcaataat tctttttcgt ttggatgttg
     5401 gtatccgtct attataccta ttttttctaa aacaagtatt tttttgcttt tttctgccaa
     5461 aaaaagaact ttttccaaat actccatctt tgaaatctgt tccagccagt ggattggata
     5521 gccaagcaag tccagccaca caaaaaagtt ttttagttgg aaatcaaaag gatatgcttg
     5581 gagattccac acgaaatgaa acatcattcc taaaaatttt ttcatactag cagaaagtag
     5641 atggccattt tcggtcagat aaaaagcttg ttcaaacagt ttaccataat ttgacaggtt
     5701 ttctgcctct aattgataaa aatagatcat ttcttcgatc atcccggcaa acggccgagt
     5761 cgttaattgc tttttatttg gatagttttt atacagattt tgcaaaaaac gatgatcaca
     5821 aatcattccg caacagataa aagtcaaaaa gtcaatctgc tttccgtcca cctgccgctc
     5881 gctgattgtt tgatcataaa cgatgcgttc tggcagattg atggtttgca gcactacacg
     5941 atttggtagc tgcaaaatcg tccgctgcgg tgttaatgct cggcttagag aacggatcga
     6001 tacagggatc atccatagtg atgaatcaag ggttgtatgt ttttgaaaaa aacctgccag
     6061 atccatgatc ccttcatttc caaatccgat gataaacatg gattgatttt cgggatagcg
     6121 tttgacgaaa tcaagcaggt tctttaattc tgttaaatga ttgcattgag tgttggcaca
     6181 aatataccag tcattgtttg cttgatttgc aaataacggg ttgatcttat ctgcaaacaa
     6241 atcataatag cgctgattcg ttaaaaataa gattggctga tcaatggaaa gttctcttag
     6301 ctgactgact agcgtttctc cgtaaaacac tttcgtcaac gcatcttcta cttgataatc
     6361 aagttccata cgcatccctc ctcttcttat ttttatttta ccattagtaa gcaaattcta
     6421 gaaaagataa gagcaaagct cacctcataa cttggaaata aataaaa
//
LOCUS       DAFEKH010000097         6410 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.100, whole genome shotgun sequence.
ACCESSION   DAFEKH010000097
VERSION     DAFEKH010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6410
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.100"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            75..1379
                     /locus_tag="LP386_002759"
     CDS             75..1379
                     /locus_tag="LP386_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBL1919934.1"
                     /translation="MLNDINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLS
                     QNSLFLKTCLLYLEEDEPDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPR
                     FTEMERRLLLLNVSYRLGGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILLI
                     GFAISFLRQQVCAVTIDSKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLF
                     NLCNYGFHSYQLIAEDFQQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIH
                     LMRSAWDNYQLFMPEKFYLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVI
                     ELSGILRLTKEHLTIYIVTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQ
                     QSSNRVLCERTLYTPDAVQYENIIPISINTIDRAIISAVQNK"
     gene            complement(1471..1836)
                     /locus_tag="LP386_002760"
     CDS             complement(1471..1836)
                     /locus_tag="LP386_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBL1919935.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(1833..2198)
                     /locus_tag="LP386_002761"
     CDS             complement(1833..2198)
                     /locus_tag="LP386_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBL1919936.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(2390..2638)
                     /locus_tag="LP386_002762"
     CDS             complement(2390..2638)
                     /locus_tag="LP386_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919937.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            2637..2765
                     /locus_tag="LP386_002763"
     CDS             2637..2765
                     /locus_tag="LP386_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HBL1919938.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            2822..4516
                     /locus_tag="LP386_002764"
     CDS             2822..4516
                     /locus_tag="LP386_002764"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HBL1919939.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKMTNTLTQ
                     EEEHVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            4520..4639
                     /locus_tag="LP386_002765"
                     /pseudo
     CDS             4520..4639
                     /locus_tag="LP386_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            4616..4789
                     /locus_tag="LP386_002766"
     CDS             4616..4789
                     /locus_tag="LP386_002766"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919940.1"
                     /translation="MQAFEHRLPRGCEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQA
                     FEHRLPRGYEKVV"
     gene            5167..6300
                     /locus_tag="LP386_002767"
     CDS             5167..6300
                     /locus_tag="LP386_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HBL1919941.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQNGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYE
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
BASE COUNT         2121 a         1222 c         1169 g         1898 t
ORIGIN      
        1 gtgggcaatt ctatgtaaat aaagaagtca atctagaaaa gctctccaat ctcctgcatg
       61 tttgcaaaac cactttgctc aatgatatca ataacataaa aaaagaattt gaagaacaga
      121 tcgcttatac acatcgggaa aaggaccgtt acactttata tttttcagaa catatacctc
      181 gatgcaagat catgcagcaa ttgtctcaaa attcgttgtt tttaaaaact tgtctgcttt
      241 atttggaaga agatgaacct gattatcttc aattaactga atgtgaattc atctctgtca
      301 gcaaagctta ttcattaaaa aaacaagtat tagcttattt taatgactgc gggatcgaaa
      361 tcgaccgcta ctcccctcga ttcactgaaa tggaaagacg tctgctgctt cttaatgtgt
      421 cgtatcgttt aggcggtttt aattcttggg agctacctga atcgtttttt gaacgtgccg
      481 atcgtttcat tgaatccgta acggaaaata gtggcagatt ttatgataaa gaaaataaag
      541 aaatcttatt gattggtttt gctatcagtt tcctacgcca gcaagtgtgt gctgtgacaa
      601 tagattcaaa atttatcgaa gaaatcaaaa aacgtcctat ttacaattat gtcgaatcag
      661 catgggaaaa cactgatttc caaacctatt ataaaaaaga agaattcgcc tttattttga
      721 cactattcaa tctttgtaat tatggtttcc attcttatca gttgattgcg gaagactttc
      781 aacagctaca ccaagtgttt attgacaata ctcccgaaat aaaagaacta gttgctacct
      841 ttgaatctca cttcaatcaa gaattattcg gaaaccaacc attcgaacgt gcgctgattc
      901 atctgatgcg ttcggcttgg gataactatc aattattcat gccagaaaaa ttttatcttc
      961 taaatgagga acagacaaat ttatataaag aagtccagac aattttttcc agctggtcca
     1021 gccagttacc ttatgatcta cggttgaatc ctaattgcat gcgggctttt gtgatcgaat
     1081 tgagcggaat tctccgtctg acaaaagaac atctgactat ctatatcgtc acaaattcgg
     1141 atgttcatta tctgatttat cgggaagcct tggaagctgt aactactttc gattttcaag
     1201 ttgcaccaac aatttattca agtatatctg atataaagaa gtatgcgcag cagtcctcaa
     1261 accgggtatt atgtgaacgt acattatata caccagatgc ggtccaatat gaaaatatta
     1321 ttcctatttc gatcaatacg atcgatcgag ctatcatttc agctgtgcaa aacaaataag
     1381 ggactgtgac aaaaatcatg tcacagcctc ttatttgttg aagatgccca tttctgtaac
     1441 aatctcttga tacacatcag gctcacaacc tcacttattt tggacatcta cgggtccgat
     1501 ctctttattt aaaaaataag aaatgatggt tcggataact accaacgccg ctagttggaa
     1561 aatatcctgc aaggtaggtt tgataatcga ttcgatgatc ccagctgaaa caagaatttc
     1621 caaacttaga agtatatagc ctcccaacat ctttttaata gcattgttct cgctgactcg
     1681 gtcgctttgc acttttgtat ggacaaataa atatttcaaa aaatccttga ttgatagaca
     1741 aacaccccaa accaataaac agatagcaaa gatatcaagt cccagtacaa gtttttcaaa
     1801 atatggaaga agaaactgca tcaactctgt cgtcatccta cctctcctct tctttgtttt
     1861 tctttgtctt ctatttcctg attcaagaaa taagaaatga ctgttcgaat gataataata
     1921 agtgcaagct tcaaaatatc tgtccaagtc ggcttgataa ctgactcgat gatatcagca
     1981 acgactagta cttccaagct taacaaaata taacttgcta gcagttttct tgtatctgca
     2041 ttacgagtat tacgttctgc atagtttttc ttgacatgag accaatcaaa aagtttgaat
     2101 agaacaagaa cgatcccgac aattaagata ccgatagaac aaatatttaa aatagcaatg
     2161 atccattcta gaaattcaat taaatttgag cgaaacatat acgctaccta ctttctttta
     2221 atttgttcct attcttttat tgtaaaagaa agttaccttg ttcgtctatt taaaagttgt
     2281 tctaatgata acggttcgct taaatttttc tttttcactc tccccttttt ctccctccat
     2341 ccataaatcg tggaagtatc caaaacaacg tagcaagtta aaataaggct tagtccgtca
     2401 tcagcttttc aaagaagcac tgtctcggtg ctttttttgt acccaaattt ctaaaaatag
     2461 aaccatacac ctcctcaaat cttttcttct tacctaccct atttttattt acaggaaaat
     2521 cagacacttc ttcttttttg tcaaaatttc ctttttcttc tcgtcctatc atttggcatt
     2581 ctaataaaaa cgaactatcc ttggatatag aaagagaaaa caaggaggcg tttttcatga
     2641 gtaaaaaatt aatcaaagtc ggcatcggtt taggtttgct tgcccttggc gctgcatatc
     2701 taggaaaaaa gacaggacta ttcgaagatg acagtcattt atatgatgaa ttcgaatcaa
     2761 tctagcatcc tatttagttg aatcactacg gacatacttg gaagacattg gaggaatcac
     2821 aatgagaaaa agtaaagcaa taatgattgg tgccggtatt gccaatatgg cagcggctgt
     2881 ttatttgatt caagaaggca aatggaaagg ggatcagatc accttttatt cattggatga
     2941 tcacggttca aatgatggtg caccgaccga cactgtagtg gatgaatatt ggaataaaaa
     3001 ccatccatta gaaaaccaaa aaggctatat tgctcgaggc ggtcgcatgc ttaattaccg
     3061 tacctatgta gatttgatgg atctgttaag tcgaatacct tctgttactg agccagggat
     3121 gactgctgaa gaagatacga gagattttga tgcaaaacac cgaacctttg acaaagcacg
     3181 tttgatggaa ggtggcaaag gaatcattga tggcggaaaa ctgggattca ataataaaga
     3241 ccgtattctt ctgactaaac tgattgctat gcctgattca gaagaagaaa aactagacaa
     3301 tatcactatc gaagaatatt tcaaagatga tccacacttt tttgaaacaa acttctggtt
     3361 tatgtgggaa acaacatttg ctttcagaac acgtagttct gctcaagaat tgcgtcgcta
     3421 tatgcatcaa atgatttatg aattcactca aatcgaacat ctagtgggcg tcaatcgaac
     3481 acgttacaat caatacgaaa gtattatgct tcctttgatc gagtacttga aagaacaagg
     3541 atgcaaaatc attttgaacc gccgtgtcac tgactgggaa ttcaaagaaa caccgatgca
     3601 agatgaaatc actgtgactg gtttgaaaat gaccaataca ctgactcaag aagaagaaca
     3661 cgttgtggtc gatgaagata cagcagttat tttcactaat gggtccatta cagattcagc
     3721 tactttagga gattacgaaa caccagctgt agaaaatatg gattatggtg cagcttctag
     3781 tctctggaaa aaagccagtg aacgtttcta caacttggga aatcctgaca aattctttgc
     3841 tgatcgagat gcaagcgaat gggtcagctt taccctgacg acgaaaaacc atttgttgtt
     3901 gaatgaaatc acccgtatca cgactcaaga accaggaaat gccttgaatt catttatttc
     3961 aaccacaccg atcacgccgt taggccaaaa agatgtcaat atgtctatcg tcgtgcatca
     4021 tcaaccgcat tttacgtctc agaaaccaaa tgaaacagtt atttggggtt atttccttta
     4081 tccaagacga cgtggcgaat ttgtggataa acagtatatt aaaatgaatg gaaaagaaat
     4141 gctagaagaa ctgattggac aactttcaaa agtagatcct ggaccagtga atattcgtga
     4201 aaaagaaaca gaaattttcg acagcgtaat aaataatatc cctgtctata tgccttatgc
     4261 ttccgcgttg ttcaataatc gtgccaaaag cgatcgacca aaagtcattc ctaaacattc
     4321 gaccaatctg gcctttacag gagaatttgt cgagcagcct tatcagatga tctttactga
     4381 acaaagtgct gtacgttctg gagaaatcgc tgctttccat tttgcgggta tccctatgtc
     4441 acgtcttgtc aaaacaccgc gttacgacaa agatattcct actctagctc gtgccgcaaa
     4501 aaaaatgttt gaataatcaa gaggttgtga aaaagctgcc ctgcatcaag taataagaac
     4561 aaccaggcta aaacagcttc ttatgttttt gatttggttg gacttattac cgcagatgca
     4621 agcttttgaa caccgtttac caagaggttg tgaaaaagct gccctgcatc aagtaataag
     4681 agcagccaag ctaaaacagc ttcttatgtt tttgacttgg ttggacttat taccgcagat
     4741 gcaagctttt gaacaccgtt taccaagagg ttatgaaaaa gtcgtttagt ttcgagtatg
     4801 aagaaaaatt ttgtgaaaat ggttcctcac gtttttgcat aaatttgact taataccgag
     4861 aaactgatcc cttctgtcat aacctctttt tatttatgtc tgtttctttt tgaaaacaac
     4921 cattttttca acgtttactc tcttgccaat ccaacatcat ctaacagata caactatttc
     4981 aatgattacc attacactaa aaaatcggaa actcacctct ccgaacacaa atacataaga
     5041 ctatagaatg tttcatttaa gaaaaaaagc gtttcattat caaaaaggta agatctcctt
     5101 taaaatgaaa ttatctgtag tactaataat gcagacaatt ttatgaatct gaaaggagca
     5161 tctccaatga aagcagtcac ttggcaagga aaacagaaaa tggaaatcag aaacgtagat
     5221 gatccaaaaa tattagaacc aacagatgca atcatccgta tcacagcaac agccatttgc
     5281 ggctccgatc tgcatcttta ccatcatggt gaagcagttt tggaaaaagg gtatgttgta
     5341 ggacacgaac caatgggaat cgttgaagaa gtgggatctc aagttcaaac attgaaaaaa
     5401 gggcaacgtg tggttatccc ttttaatatt agttgtggtc attgtcattt ctgcctgaat
     5461 cacatggaaa gccaatgtga tgaatcaaat ccagatcagt tatatggcgg gcttttcgga
     5521 tttggcaagt tgaacggtaa tcattggggt ggtcaagcgg aatatctaag agttccttat
     5581 gcagactcta cttcatttgt tgtaccagat aatgatcttc ctgatgaaaa agttttattt
     5641 ctatcagata ttttgcccac agcttattgg agcgttgaaa acgcaggagt aaaaaaaggc
     5701 gatacagttg tgattctagg ttctggtcca gtcggtctat tcgctcaaaa attcgctgtt
     5761 atggctggag cagagcgcgt aatcgcagta gatccagtac agcaccgtct agataaagcg
     5821 gctaattaca atggggttga aacttatttc ttagaagaca cggcacaagc tggaacagaa
     5881 ttgtatgaac tggctaaagg tggcgcagat gtcattatcg attgtgtagg aatggacgga
     5941 ttagagcctg tcaaagaaaa agcgaaaaat ttagtaagct tacaaaacgg cacaatctct
     6001 ccattacaga tggcatcgca agctgtcaaa aaatttggaa cagtccaagt aactggtgtt
     6061 tatatgactc cagcttcttc ttacccgctg caagaatttt ttatgcggga tatcgctgtc
     6121 aagcatggac aggcaccaat tatccatcta atgccaaaaa tttacgaaat gattgcagaa
     6181 ggactattcg atcctacaca aatcattact cattcgctgc cactatcaga agcagcacaa
     6241 gcatatgaga tctttgacaa aaaagaagat aaaaatataa aagttgtttt gaaaccttga
     6301 attcagtaaa aaatacaggt gattttcttt atgcccaaaa tcaaacgaaa tacccatgag
     6361 atcgaaatag gaaaagaaga agatatcgaa atacgaggac gtcgcttccg
//
LOCUS       DAFEKH010000098         6385 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.101, whole genome shotgun sequence.
ACCESSION   DAFEKH010000098
VERSION     DAFEKH010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6385
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.101"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..115)
                     /locus_tag="LP386_002768"
     CDS             complement(<1..115)
                     /locus_tag="LP386_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBL1919942.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDR"
     gene            246..698
                     /locus_tag="LP386_002769"
     CDS             246..698
                     /locus_tag="LP386_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919943.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            712..1401
                     /locus_tag="LP386_002770"
     CDS             712..1401
                     /locus_tag="LP386_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919944.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1526..3877
                     /locus_tag="LP386_002771"
     CDS             1526..3877
                     /locus_tag="LP386_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HBL1919945.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3957..4352
                     /locus_tag="LP386_002772"
     CDS             3957..4352
                     /locus_tag="LP386_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919946.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4677..5294
                     /locus_tag="LP386_002773"
     CDS             4677..5294
                     /locus_tag="LP386_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1919947.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5335..5634
                     /locus_tag="LP386_002774"
     CDS             5335..5634
                     /locus_tag="LP386_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HBL1919948.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            5668..5835
                     /locus_tag="LP386_002775"
     CDS             5668..5835
                     /locus_tag="LP386_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBL1919949.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(5880..6227)
                     /locus_tag="LP386_002776"
     CDS             complement(5880..6227)
                     /locus_tag="LP386_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1919950.1"
                     /translation="MEFREGAFDFQTSQQNQLLDTAMFDMFLSLLSYIAQNEREKIRE
                     RQRQGVLLAQKAGRYKGRPIEYSINSTDPQKRLVFKTVVDMLKQGIPVAEIAKENGIS
                     RPTIYKIKKANDL"
     gene            complement(6233..>6385)
                     /locus_tag="LP386_002777"
     CDS             complement(6233..>6385)
                     /locus_tag="LP386_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBL1919951.1"
                     /translation="NKFYQSLRTASSTIKGMETIRGIYKKNRRNGTLFGFSVSTEIKV
                     LMGITA"
BASE COUNT         2184 a          898 c         1279 g         2024 t
ORIGIN      
        1 cacgatcata taagatttct tgaacttcac gatagctaag gttataacga agatagtagc
       61 ccacggctac aataatcaca tcctgctgaa attgctttcc tttaaaatga ttcatcgtta
      121 ttcctcctgc tatctttttc tattattcta tcttatttga tagtagattt aaaactttgc
      181 aacagaacca attatcttat cgtagatata tattataaat ttaataagaa agcgaggtga
      241 gaatcgtgaa aaaaacgata ctaagtattt tttcagtatt tacaatatta attgggggct
      301 attttctttt gaatttagat tctgttaatt caaacgctca aataaaagat caaagagtag
      361 ctgaacataa taataaaaaa atgagtttga ccaaaaatat ctattctatg tcagatgaag
      421 aattgtataa agaatttggt gatttatccg gggaacagtt agaagaaagt attccaggaa
      481 ttagtgactc agataaaatt gttgtcttgt ctgctggtgg gcaattaatg ggagatggca
      541 aatccgaatt agttagttat aaacaaaatc acagacagtt tattgatgtt aatactgatt
      601 ccaacgctat ttcgattaag gatctaaaag agcttttaaa tagtaaaaga aatgaattaa
      661 agcagataaa agaaactaat tcagtggaat tagagtaaag gaagattcat tatgaaaaag
      721 atttttggtg tttctgttgg gctacttatg atgttaacat ttggaaatgc agtatatgct
      781 gctgagaaag aagttatttc agatccagag cagtacgcct cacgatactt tgctgatttt
      841 gaagaagaag ataaagtact tgcattgcca gaaggtggtt ttttaaaagg ggaagctaaa
      901 attgtatcta tggataatcc agatataatt caaggttcat ataattcaga aactgatcct
      961 gcttcagttt cagtgacaga agcaaaaaaa attgttgctg aaaaattcaa aaatgatatt
     1021 gaaactactc caattatgcc tcgaggagca tttccacccg atgttggtac tagcggacac
     1081 cttcttgtac tagcaggagg aggaagctat aaatcacagc catttagtgg tgcgggatgg
     1141 cgttttggag gtatgggtgt aaaaccagct gatggtacag gcaacttttt acgttggaaa
     1201 tcctacattg acgatggaag agtaggaaat gtaaatcaag ccaacgcaac taaatctggt
     1261 tctattcaag gaatggcatt gtatgctcgt gaaggattca aatactttgc accaaacggg
     1321 cctggttgga caatgaatat aggtatttat tacacttata atcctgttgc aggtacgtat
     1381 tatgttgttc aaaatattta ataaaacagc acaaagagat ttctttgtgc tgttttatta
     1441 tttttagttg ttgacaaaca ctaaaatata aaatataatc aacacataaa cgaacgtatg
     1501 ttcggcaaga aagcagggga tttttatgga tgagatggtt ttaagtactc agaaatggct
     1561 aaacaagaaa tacagtaatg ttacagggtt tgataaggtt ccagaaaatg ggcgaacagg
     1621 gtggcctaca atctatggac ttattgaagg actacaagta gaacttggta ttactaatct
     1681 agtagctaat tttggaccta ccactgaaaa aatgtacgat aatcaggtta ctcctaaatg
     1741 gggcaaaaat ctacctaaaa atattgtatt tcttattcaa ggtgcctttt ggtgtaaggg
     1801 gattaatcca ggtggcttcg atggggtata tactccatat ttagatactg ctgtaaaaga
     1861 gttgcagact gatgcagggt ttaatggaag cgctgtaact ggagttttgg atgcgaaatg
     1921 ggccaaagcg ttatttgata tgagtgcttt tgttcttgtt cccggcggag atagtaaaat
     1981 tagaaaaatg cagcaatggt taaatgtaaa ttatttagaa tacacgggaa taatgccttg
     2041 tgatggtatt tatcaaagaa attcaaatca agcattaatt tttgcattac aagctgaact
     2101 aggatattct cccagtgaag caacagggtc ttatggtaat gggacaacta gtaaaactta
     2161 tcctgtgtct gaaggtaact cgggaaacta tgtaagaata attcaatatg gattatatgt
     2221 taatggttat tttgaagacg gtacattcga tggtattttc actaaatata tgggtttaga
     2281 agtactggca ttccgaaaat ttatggtatt gcctgaatat actgaaatag cagatgttgt
     2341 tgtaataaaa ggactattgt ctagcgctgg agatattaga agatctgcag atggcgcaga
     2401 tacttctacg caattaacta gatctcaaat ccaaacattg gttgataatg atataaaaat
     2461 agttggtaga tatcttactg gtactgttgg aattggaaaa gatgaacgaa ataagtatct
     2521 aactacagag gaattgaata atattttttc taaaaattta tctgtgtttc ctatctatca
     2581 agatggaggt gcagcattag cttattttac ttatgatcgt ggcttatcag atggtaagaa
     2641 ggctatagat gcagcaaaaa atctaaatat accattaaca acagttattt attttgctgt
     2701 tgatctagac atgttagggg aagaaattct tgcatatgct ggagaatatt ttaagggggt
     2761 atctgctgta atgtcatata gcgggtatca aacgggtgtt tacggaacaa gaaatgtttg
     2821 ttctcaaata atcaataacg ggtatgcttc gtttgcattt gtttcagata tgtcgactgg
     2881 ttatagtggg aatttaggtt ttcctatgcc tagacaatgg tcttttgatc aatttgttga
     2941 atttaccata ggaagtggca acggagctgt tggtatcgat ttaatcgcta catcgggtag
     3001 agatagcgga tttaatgagt tatcaaatga tactaataat gataattaca ttgccaaata
     3061 caatcagaag gttataaatc agatggtacg tgcgtatcaa tatctatcac aagctggtct
     3121 tgataatcct tggaaccctc atttgacatt ttatagatat gtaaattatt ctggtttgtc
     3181 atgggacatc atttcttctc ctgtaacaga gcatgataga aaaatttatg atgaatatag
     3241 gaataaatta actaatagcg agggcctgta taattatttt atagatccta atactggttc
     3301 aataataggt ttgcctcact taattgtgac gttacaatca cagatgtttc tagccgacac
     3361 aatcaatgat agtgtttctg actttgcagg ttggttagga gatttaatga cttgctgggg
     3421 tgaagttaag aaattaggaa tacaaatgga gcaaggtgta tttgcattag taggtacggc
     3481 tgcaggtgga acatttagtc tagaagattt ataccaagat gttgacgcgg taaatgttta
     3541 taccttagca aaaagaaatt ctgattcaac agctttatcg gctttaaaaa cgtactattg
     3601 tgataagggt gctattgata gatttaatca atttgttaag aacagatttg gttcttcaga
     3661 taaaatcgct tcagtaacaa atagtttatt agaaaatgac gaaacagttg atatcttagg
     3721 tgtagggata atttcatttt tcattgataa aatagttaat aattcacttg ggacagattt
     3781 tacttatctt gattttattg gagatgaggg gaaagttgca aatggatttt ctgaaaaaat
     3841 tattcaattt caagaaaata gaagtaaact taattaagaa tcgtttacta tttaaacagt
     3901 gtccttttcc tttttaaata tatacgataa aataagtata tgaattgtaa aaggacatga
     3961 tgattatgga agaaatagaa tggaataatc tgactcaaaa taataaaaat aattctggat
     4021 gtggaattat ctttatgttt gttatagttt tgggaatagt agtactttta ataactgtca
     4081 agatagtaga ttactttgcg aatactcctg aagaacaaat acagagaaaa cttcctgagt
     4141 ttgaaagagt accaccttat gatccaagag ataattcatt tcaagtaaaa aaattaaaag
     4201 agtctccaaa tgaaatgtgg tttgaagtta cagttgaatc aagcgacttc aaagaaaaaa
     4261 agaaagaata caattatatt gtaaaggcaa aagtatcaaa aagatttatt tttaacccta
     4321 aattagaaat atatagtgtt gtaatagaat aatagtgtta aaaaaattgt aaaagttaaa
     4381 gaagtcaaat tctgatgtga aaaataaaat ataccatgga agacataaaa gaaaaactgg
     4441 ataactagtt tatttaatgg cagaccgtta aggcctgcca tttttatgta ttttagcgga
     4501 ataaatataa tcatgcggga gtgtaaactt actgtttcaa aaagtatact ttttgacatg
     4561 ccttgatttt ctttgtttat gtatggcata ataaccacat aatacaattt gaaacgtttc
     4621 tgatttaatc tgattgtttt gaaacaattt tagtgaaaaa agggtagata aaaacgatga
     4681 gaaaattttt ttatatccgg gtcagtagtt atgatcaatc gatcgaacga caactgattt
     4741 ccgcgaagga attaggaatc cctgaagaat atatatttgt agaaaaagcc agcggcaaag
     4801 attttaaacg ccctgaatat caattaatga aacggatgtt tcgaaaagga gatttactct
     4861 atctacaatc attagataga ctaggcagaa ataaacaaat gattttagaa gaatggcgag
     4921 aattaactaa ggaaaagcag attgatattt ctgtgttaga catgcctctg ttagatactg
     4981 ctagttacaa gcaactagat gggttagaga cgcttatctc tgacttaatt ctgcaattac
     5041 tcagctatat ggccgaagac gagcggaaac gaattaatag ccggcaaaga gaaggcgtag
     5101 aagctgcgaa acaaaagggt gtaaaattcg gcagaaagaa aattgcttta cctcctgaat
     5161 ttcctgcgat ctattctgac tggaaagcag gaaagataac tgcagtctat gctatggatc
     5221 aattgggcat gaaacgaaat accttttatc gacgggtgaa agaatatgaa cataccttgc
     5281 accacttttc ttgatagata taacagctat tagacgggaa gggagagttt gaaaatggac
     5341 ttaacgaatc aaagggtcgt ttttactgga acgctgcagc aaatgacacg aacccaagcc
     5401 atcggtttgg ttcactcttt aaacggccat tgtcaatcaa gtgttacttc aaaaacaaat
     5461 ttcctggttt gtggtcagta ttctaagtcg ttgtttgatg attctctcta tacaaaaaag
     5521 gaacaaaccg cgcgggactt gattgcgtta ggtcatgaga ttaccatttt atcagaagtc
     5581 gaattttatg cgttaattag tcaacagttg aaagaatggc aacggtattt ataatcgtta
     5641 gtaaaattta caaggaggaa aatttttatg aagcgaaaat cttatgatcg ttggggcatt
     5701 gaaataacta gttttaatcg aaatattgct tttcacgtgg agtgtgactg tggggaatta
     5761 gcaaaaagtg tttatcaaaa aaattacttt tactgtccta aatgccatcg ccgatacggg
     5821 gtacatggaa catagaaacg aaatagtgcg gtagaaaagc gaatgaatgt agtatatttc
     5881 tacaaatcat tcgctttctt tattttataa atagttggtc gagagatccc gttttctttt
     5941 gcaatctctg caactggaat gccttgcttt aacatgtcca ccacggtttt aaaaactaag
     6001 cgtttttgcg gatctgttga gttaatagaa tactcgattg gtcgtccctt atatcggccg
     6061 gctttttgag ccaataatac tccttgccgc tgacgttcac gaattttctc acgctcgttt
     6121 tgtgcaatat aacttagcag tgataaaaac atatcgaaca tagcggtatc caggagttgg
     6181 ttctgttgcg aagtttgaaa atcaaacgcg ccctctctga actccaaata tcttaggctg
     6241 ttattcccat taataccttg atttcagtag acaccgaaaa gccgaagagc gttccatttc
     6301 ttcggttctt tttatatatt cctcgaatgg tctccatgcc cttaatcgtg gaagaggctg
     6361 tacggagact ttgataaaat ttatt
//
LOCUS       DAFEKH010000099         6267 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.102, whole genome shotgun sequence.
ACCESSION   DAFEKH010000099
VERSION     DAFEKH010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6267
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.102"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(95..667)
                     /locus_tag="LP386_002778"
     CDS             complement(95..667)
                     /locus_tag="LP386_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL1919952.1"
                     /translation="MTNKDQNKNYLEAIILELQNNSKRINSVELEQFSEKIVQAKHIF
                     LAGAGRSGIAMQAFTNRLMHLGFSVSLVGEISSPHSQPGDLLIICSGSGETGSLKNLA
                     AKANQSGVSIALVTMKKDSSIGQLADSVLVLPGITKDENQREEDTFSQPMGSSFEQLA
                     FLTFDSLVLSLMDKTGESSETMFARHADFE"
     gene            complement(674..1336)
                     /gene="rpe"
                     /locus_tag="LP386_002779"
     CDS             complement(674..1336)
                     /gene="rpe"
                     /locus_tag="LP386_002779"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBL1919953.1"
                     /translation="MTIAPSLLNAPIAEVKELFEILKEKNVDYLHIDVMDGCFVPDMA
                     FGPSVIKDIRPLTDVVFDVHLMIDTPEKIVTRFVEAGADIVTFHIEATKHAMKVIQLV
                     KEAGAKVGITFNPATPVSFIEPVLSLVDQVLVMTINPGTENKHFIQETVVKIEQLDVI
                     RKQNDYTYDIEVDGKIDNQTIKVCSKAGADIFVSGGFIFNGKNTPQEQIDKLNQSLEE
                     VK"
     gene            complement(1352..1867)
                     /locus_tag="LP386_002780"
     CDS             complement(1352..1867)
                     /locus_tag="LP386_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HBL1919954.1"
                     /translation="MRFHHDTLTIETVSGRPSYHDIRKELLDTVDTAGIENGMLVISS
                     PHTTCSLFFEETMHDTNFFGDDYLHVDINNVMETIIPKMTSENQYNSPGPKHIDFGTR
                     LSDPNYPAEKWVMLNTDAHLRSSIYGTNSMTLIVQEGKLLLGEMGRVYFVDWDQLRER
                     TRTINLMIMGE"
     gene            complement(1869..2153)
                     /locus_tag="LP386_002781"
     CDS             complement(1869..2153)
                     /locus_tag="LP386_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1919955.1"
                     /translation="MKKLLVICGAGHATSTIAVAKLSKWLEEEGLTDQVKIYQSKIAD
                     ELNKIDEYDAVVSTTIVPDVIKAKVTNGLGLLTGIGTDAIYADVKERLGV"
     gene            complement(2187..3515)
                     /locus_tag="LP386_002782"
     CDS             complement(2187..3515)
                     /locus_tag="LP386_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBL1919956.1"
                     /translation="MDIVLNAFEWFIGLGSNVFLPLIIFVIGILFGLKPGKAFVSGVT
                     VGIGSIGLGLVLSLLSDGLGTAIQQMGEQYGGGLNILDIGVGVGGPLAYSTSLGILMI
                     PISLILNFIFVVLGWTKTLNVDIWNFWFAIFLGMITQSVTGNFWFGLIGAIVAVILQW
                     FLADRTQKTVSEFFGYPGISITHMMGLSGVLFAKPVNWVFDRIPGFNKIDADAETLTK
                     RFGVLGDTVVIGLIIGIVVGIMAGYDVAGIGNLGIMTAAVMKIMPKMVAMFMEGLMPI
                     AEAAKEFTNKKLNGRQVNIGMDAALTVGHPTIMSTSLLLVPISLLLALILPGNKVLPF
                     GDLAFFAFAICLMIPYFKGNIVRSLVGCSLYVVTTLYMATWLAPIITDVFTLASFDVG
                     TAGLVTMLLCGLWPVGLFVLLASYFGVIGIGGLGVVLVGASIYMNKVKKA"
     gene            complement(3529..3984)
                     /locus_tag="LP386_002783"
     CDS             complement(3529..3984)
                     /locus_tag="LP386_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL1919957.1"
                     /translation="MYLDKELCLFQLEVKDQKELFQVMSEQLKNAGCVKDSFLEGITN
                     REQEFPTGLEVNQIGFAIPHTDSAHVNSSQICFASLKEPLVFSDMTDKSHEIPVRLVF
                     MLAMSQPHEQIDTLQNLVSLFQNEEKVNELLACTTKEAFIELVHSAGVY"
     gene            complement(3987..5933)
                     /locus_tag="LP386_002784"
     CDS             complement(3987..5933)
                     /locus_tag="LP386_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL1919958.1"
                     /translation="MIERHVNLLKLLSRQEDFKPASFFSDKLAVSTKTIYQDIELLED
                     YVVNYQVTIERLPSLGIKLIGDRKNVEHLISSVENYLEKDIYSPEKRRVEIIKEVLFG
                     DKPVSLTHLSQSFMVSKTSLYNDLRIINKIIGSGEVKLQSSAEGISFTGNEQAIQRAI
                     KQLVFYYANDMESKTFFQVLNMLFDSKVISVIHDLLFNDYSELTEKVSDYYVRSLIST
                     LVIQCNRLLKGHHLTVEEEFLFNSIRYMETYIVANGLIEELKAKLNLPFYDADKEYLC
                     RQLFAHRVTNNLKTSNEEYAMSVHKLIERMSEIEKIDLTQNDRLYQSLLYHVPAMVLR
                     LKKGIKIQNPLLENIKSQYSELFSIVWYAMSILEEEFDVTLTDDEVSLILIHFQIAIE
                     DQSKANNIIIICQYGISSAQLIYNKVRRFLPAKDNVEISTLDKFHLAEIGEVDLIISS
                     LSFDAGGIPLVRVSPLVSKTDYMNIMEAYTKYLIEEPSRFIQNELIPKAVKVPTISKF
                     VQSSLVKTGVQVESKEECLDLMISELEANSLVTEEFRASIFSREKMGNTNLESGVALP
                     HANPSMVIESNIFIVALKNAINWGDRKVKLVIMVSLAEEDVSEIRGVYEELYQFIGQK
                     EMVDRLLQVHDSEKLLRIFQQKGE"
BASE COUNT         2061 a         1205 c          875 g         2126 t
ORIGIN      
        1 aattattaag ttatgtctaa tcaaataaaa aaaccattct catatttgct gaataattag
       61 catttagaga atggtttttt atctttaaaa tctactactc aaaatctgca tgtcgagcaa
      121 acatcgtttc tgagctttca cctgttttat ccattaaaga taacactaaa ctatcaaagg
      181 tgagaaatgc taattgttca aaacttgaac ccataggttg tgaaaaagta tcttcttctc
      241 gttgattttc atctttggta atacctggta atacaagaac agaatctgct aattgaccaa
      301 tcgacgagtc ttttttcatg gtaactaaag caatgcttac accactttga tttgctttgg
      361 ccgctaaatt ttttaaacta cctgtttcac ctgagccaga acagataatt aataaatctc
      421 caggttgcga atgtggtgaa ctaatttcac cgacaaggct gactgaaaaa cctaaatgca
      481 ttaagcgatt cgtaaatgct tgcatggcaa ttccagagcg tcctgcacca gctagaaaga
      541 tgtgtttagc ttgaacaatt ttctcactaa attgttctaa ctctacagaa ttaatacgtt
      601 ttgagttatt ttgtaattct aagataatcg cttctaaata gtttttattt tggtctttat
      661 tggtcatgat cttttacttc acttcctcta atgattgatt tagtttatca atttgttctt
      721 gcggggtatt tttcccattg aagatgaaac cgcctgatac aaaaatatcc gcccctgctt
      781 tagaacaaac tttaatcgtt tgattatcaa tcttgccatc tacttcaata tcatacgtat
      841 aatcattttg tttgcgtatt acatctaact gttcgatttt aactactgtc tcttgaataa
      901 aatgcttatt ctctgttcct ggattgattg tcattactaa tacttgatcg actaaagata
      961 atactggttc aataaaactg actggtgttg caggattaaa agtaatccct acttttgctc
     1021 ctgcttcctt gactaactga atgaccttca ttgcgtgttt ggtagcttca atgtggaagg
     1081 taacaatatc tgctcctgct tctacaaatc ttgtgacaat tttttctggt gtatcaatca
     1141 tcaaatgaac atcaaacaca acgtctgtta gtggacgaat atctttaata acacttggtc
     1201 caaaagccat atctggtaca aaacagccat ccattacatc aatatgcaaa taatcaacat
     1261 tcttttcttt taagatttca aataactctt taacttctgc gataggtgca tttaacaatg
     1321 atggagcaat tgtcattctc tattcccccg tttattctcc cataatcatg agattgattg
     1381 ttctagttcg ctctcttagt tgatcccaat cgacaaaata gacacggccc atttctccta
     1441 ataaaagttt accttcttga acaattaaag tcattgagtt ggttccataa atagatgaac
     1501 gtaaatgtgc atcggtattt agcatgaccc atttttctgc agggtaattg ggatcagata
     1561 atcttgttcc aaaatcaatg tgttttggcc ccggactgtt gtattgattt tcactcgtca
     1621 tttttggaat aatcgtttcc attacattgt tgatgtctac atgtaaataa tcatcaccaa
     1681 aaaagtttgt gtcatgcatc gtttcttcaa aaaagagtga gcaagttgta tgcgggctcg
     1741 aaattactaa cattccattc tcaatacctg ctgtatcaac tgtatctaaa agttcttttc
     1801 gaatatcatg atacgaagga cgccctgaaa ctgtttcaat agtcaaagtg tcatgatgaa
     1861 aacgcatatt aaacacctaa tctttctttt acatctgcat aaatggcatc tgtaccaata
     1921 cctgttaata agcccaagcc attcgttact ttagctttaa ttacatcagg gacaattgtt
     1981 gtacttacta cagcatcata ttcatcaatt ttatttagct catcagcaat tttagattga
     2041 taaattttca cttgatctgt taatccttct tcttccaacc attttgataa ttttgctact
     2101 gcaattgtag aagtagcatg acctgctcca caaataacta ataatttttt catattgatc
     2161 tcttctttct tattttaatt ttatgattaa gctttcttca ctttgttcat gtagatagaa
     2221 gcacctacta aaacaactcc taatccacct attccaatta caccaaagta agatgctaat
     2281 aaaacaaaca accctactgg ccataatcca cataacaaca tagttactaa tcctgctgtc
     2341 cccacatcga aacttgctaa tgtaaacaca tcagtgataa ttggtgccaa ccatgttgcc
     2401 atatataatg ttgtaacaac atacaacgaa catcctacta atgatctcac aatatttcct
     2461 ttaaaataag gaatcattaa acagatggcg aaagcaaaga atgctaaatc tccaaaaggt
     2521 aatactttat ttcctggaag aattagtgct agcaataatg agattggtac aagcaataga
     2581 gaagttgaca taatagttgg atgacccaca gttaacgctg catccattcc aatgtttact
     2641 tggcgaccat ttaacttttt attcgtaaat tctttcgccg cttctgcaat tggcattaaa
     2701 ccttccataa acattgctac cattttaggc ataatcttca tcactgccgc agtcataatt
     2761 cctaagtttc caattcctgc tacgtcatag cctgccataa tacccactac aataccgata
     2821 attaggccaa taacaactgt gtcacctaaa acaccgaaac gttttgttaa tgtttctgca
     2881 tctgcatcta ttttattaaa tccaggaata cgatcaaaaa cccaatttac tggtttggca
     2941 aatagtactc ctgataatcc catcatatgt gtgatagaga ttcctggata gccgaaaaat
     3001 tcgctaacag ttttttgtgt acgatctgct aagaaccatt gtaaaattac tgcgacaatc
     3061 gcgccaatta agccaaacca aaagtttccc gtaacagatt gagtaatcat acctaggaaa
     3121 attgcgaacc aaaagttcca aatatcaaca ttcaatgttt ttgtccaacc caaaaccaca
     3181 aatatgaagt taagaattaa tgaaattgga atcattaaaa ttcccaatga tgtagagtaa
     3241 gccaaaggtc caccaacacc tacgccaata tctaggatat tcaggccacc accgtattgt
     3301 tcccccattt gttgaattgc tgttcctaaa ccatctgata ataaacttaa aactaatcct
     3361 aaaccaatag aaccgatacc aacagtaacg ccggaaacaa atgctttacc aggttttaat
     3421 ccaaataata tcccgattac aaaaataatc agtggtaaaa agacgtttga ccctaatcca
     3481 ataaaccatt caaaggcatt taatacaata tccatctctc tattcctcct aataaactcc
     3541 tgcagaatgt actaactcaa taaatgcttc tttcgtggta catgcaagta attcatttac
     3601 tttttcttca ttttgaaata ggctaactaa gttttgtagt gtatcaattt gttcatgagg
     3661 ttgtgacatt gccaacataa agactaaacg tacaggtatt tcatgagatt tatctgtcat
     3721 atctgaaaat accagtggtt cctttaatga ggcaaaacag atttgagagc tatttacatg
     3781 tgcggaatct gtatgtggga tagcaaaccc aatttgattt acttctaatc cagttggaaa
     3841 ttcttgttca cggttggtga taccttctaa gaaactatct ttcacgcaac cagcgttttt
     3901 taattgttca gacattactt gaaacaattc tttttgatct ttcacttcta attgaaataa
     3961 acataattct ttatctagat acatttttat tctccttttt gttgaaaaat tcttagtaat
     4021 ttttcgctat catgaacttg taacaagcga tcgaccattt ctttttgccc aataaattgg
     4081 taaagttctt catatactcc tctaatctca gatacatctt cttcagctaa actaaccata
     4141 atgactaatt tgacttttcg atcgccccaa ttaatcgcat tttttaatgc tacaataaaa
     4201 atgttggatt caatgaccat tgatggattc gcatgcggta aagcaacacc actttctaaa
     4261 ttagtattcc ccattttctc tctagagaag atagaagcac gaaactcttc agtaactaat
     4321 gaattggctt ctagttcgga aatcatcaaa tccaaacatt cttctttgct ttccacctgt
     4381 actcctgttt ttactaaaga tgattgaaca aatttagata tggtgggaac tttaaccgct
     4441 ttaggaatca gttcattttg aataaatcgc gaaggttctt ctattaaata tttagtataa
     4501 gcttccataa tattcatata atctgtttta cttaccaatg gagataccct tactaagggt
     4561 ataccacctg catcaaagga aagagaggaa ataatcaaat caacttcccc aatttcagct
     4621 aaatgaaact tatctaaagt tgatatttct acattatctt ttgctggtaa aaaccgtcga
     4681 actttattgt aaattaattg cgcagaagaa ataccgtatt ggcaaataat gatgatatta
     4741 tttgctttgg actgatcttc aatagcaatc tgaaaatgaa tcaaaattaa ggaaacttca
     4801 tcgtccgtta aagtcacatc aaattcttct tcaaggatgg acatggcgta ccatactatg
     4861 ctaaagagtt ctgaatattg agatttgata ttttctaata acggattttg aattttaata
     4921 ccttttttta aacgaaggac cattgctggc acatgataca ataaggattg atataatcga
     4981 tcattttgag tcaaatcaat tttttcaatc tcactcattc tttcaatcaa tttatgaacg
     5041 ctcatagcgt actcttcatt gctggttttt aaattatttg tcacacgatg tgcaaatagt
     5101 tgacgacata gatattcttt atctgcgtca taaaatggaa gattcaattt tgccttcaat
     5161 tcttcaatta aaccatttgc cacaatgtac gtttccatat agcgaatgct attgaagagg
     5221 aattcttctt caacagttaa atgatgacct ttcagtaaac ggttacattg gataactaaa
     5281 gtagaaatca atgaccgaac atagtaatca gaaacctttt cagtcagttc actgtaatca
     5341 ttgaatagca aatcatgaat gacactaata acttttgaat caaacaacat atttaaaact
     5401 tgaaaaaatg tttttgattc catgtcattc gcataataga atacaagttg cttgattgct
     5461 cgttgaattg cttgttcatt accagtaaaa ctaattcctt ctgcagatga ctgcaactta
     5521 acttctccac tgccaataat tttattgata attctcaggt cattgtataa cgatgtttta
     5581 ctaaccataa aactttgaga caaatgagtt aaagaaacag gcttatcacc aaacaaaact
     5641 tctttaatga tctcgacacg tcttttttct ggagaataaa tatctttttc aagataattt
     5701 tctaccgatg aaatcaaatg ttcaacgttt ttcctatcac ctatgagttt gatacccaaa
     5761 gaaggtaatc gctcaattgt tacttggtaa ttaactacat aatcttccaa caattcaata
     5821 tcttgataaa tggtcttggt cgacactgcc aatttatcac taaaaaaaga agcgggttta
     5881 aagtcttctt gtcgacttaa taattttaat aaatttacat gtctttcaat caaacttgtt
     5941 cacctcttaa cgctagcatt tgttacctct tttcattatt tattctagca ctggaacccc
     6001 cttccctcaa ttacatctat gtcaataata cttgtggaag tttgttgtaa aggaaatcca
     6061 aataatctta aaaaatgaga aacaaaaaag gagaaatcct taaaagagct aagatattcc
     6121 aatagaaaat actccttatt atggaagtaa tatgaaatat tacaattgaa aaataaaaac
     6181 aatataatgg cgtcactaaa attcgtattt ttttattata atataactta attacaaatg
     6241 ctcatctatg aacaattgag tcctaat
//
LOCUS       DAFEKH010000100         6136 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.103, whole genome shotgun sequence.
ACCESSION   DAFEKH010000100
VERSION     DAFEKH010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6136
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.103"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(207..1169)
                     /locus_tag="LP386_002785"
     CDS             complement(207..1169)
                     /locus_tag="LP386_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1919959.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1171..2610)
                     /locus_tag="LP386_002786"
     CDS             complement(1171..2610)
                     /locus_tag="LP386_002786"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HBL1919960.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2795..4741
                     /locus_tag="LP386_002787"
     CDS             2795..4741
                     /locus_tag="LP386_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HBL1919961.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKINGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            5005..5877
                     /locus_tag="LP386_002788"
     CDS             5005..5877
                     /locus_tag="LP386_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL1919962.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIENRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT         1947 a         1055 c         1083 g         2051 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacagt tgtgtaaaaa tatcatttta gagcatgaaa
       61 aaaggagtgg atttctccac tccaaaaaag tctaactttt gggggtcact acaagttgac
      121 aactcctttt tgtttacaaa tcaattggat atctacaaat tgtattttct aacgaatttt
      181 atagacatta aaaaattaat ttaacgttaa atacttcctc cagaaagtat tgagattggt
      241 aaaatataat ccttatttgt cttttcgcct ttaatttttt tcagaagaat atcaacaata
      301 agacttgcaa tttcatcaat tggttgtctt attgttgtca attgtgggaa aaatttctca
      361 ataaaagagg taccatcgta tccaataatt tttaaatctt ctgggatatt aagtttaagt
      421 tgatgagcaa ttttcatagt gagaatggct gttaaatcat cagaaacaaa aataccatct
      481 ggtttgtgat ttataatagt tgactttatt tccatttcac gacggatagt agacagatta
      541 ttaggaattt tgaaaatttt tccatttgga ttttgaaaag aaaaacctag tgcacgtaat
      601 tctgtgggag aatccgtgtt atcatttcct gtaatcataa tggtattttg acaaccattt
      661 ttttgtaaag tcttagctgc aagttttccc ccttcaaagt tatctgaaga aacaatggaa
      721 acattaggag ctaaatttct atcaaaagca acaataggtg ctctcacacg ctcataatca
      781 gcaattccaa gattatggct tgatgagatt atgccatcaa cttggttggc ttcaagcatt
      841 tcaatgtatt ctctctcttt agcaggatca ttttgactat tgcaaataat cgttttatat
      901 ccatgtttaa ataactctat ttcgagatac tcaatgagtt cagagtaaaa gatattacta
      961 atattaggaa aaataagacc aataagctga ggtgactttc cttgaagtcc acgtgctaaa
     1021 ttatttggtt tataaccaag agttttcata gcttcatgaa ctttttgttt tgttttttct
     1081 gataaatatc ccttattatt aatgacgcgt gaaacggttg ttgggctaac tccagctaat
     1141 tcagcgacat cagttaattt tgctaccatt ttaatatttt aattcaaagt attttccagt
     1201 aggttcgcct gatttgattt gaataccatt ttggtgattt tcagggaata cacgactagt
     1261 aaacactttt tctcctttat taataaaaat ctcaatgatt gagttatcta caaaaatgtt
     1321 agcagttgtt tctttagtat caattgagca ttcacgaatc gtaccaaagt cagtggcata
     1381 ttgaatgcct gctttgctgc gatctaaaat aatttttcct tctttggtat ctacaatcaa
     1441 gctaagtcca tttcctttac tatcagagaa aagaagtaac tccgatttct gatttggagg
     1501 aaaagttagt tcaagctcat aagtattatt tgtttctgct tttgctgtaa attgttcaga
     1561 actagcacgt aatgatgtaa tagcttctac tggatattgg taaagtttac catcttttat
     1621 tgaaagttct tttacaagac tcattgctcc ctgataatca tacttatcag ttggataatc
     1681 gatatcaggt agtccaatcc aactgacaat cagagcacga ccatcaggag tattgaatcc
     1741 ttgagtcgca tacgcttcaa atccataatc aagattttga atttctgaag cgcccacaag
     1801 ttttactttt tctatgtcaa gcgattgaca gatcttaaaa gtattcggat agatattccc
     1861 ataatttagc tcagatttat ccaacccttg aggacaataa atgagaacag gttttttgtc
     1921 tacaaatact agatttggac actcaatcat gtattctgaa ccagtgccgc caaaatcaag
     1981 gttgccaact tcctcccatg tttccacgtt attgtcatcc gctttgtaaa gtttgataaa
     2041 gcctgatttt tctaaatttt gtgctccaac aatcgcatac aattgtcctt cataattaaa
     2101 catttgtgga tcacgaaaat gatcagttac atcagcaggt ttatgaataa gaacattctc
     2161 acctttcgta atgttgtagt ctttatccat ccatgctccg atttgaagtg tatcacgttc
     2221 ccaattttca tttcgaacgt ttcctgtata gagtaagaat agattcccct ctatttcata
     2281 tgcagaaccg gaataagcgc cgtggctatc tcgttttgtg tctggaagaa gttctgctcc
     2341 tgttacatga aaatgaacta aatcatctga ttcattgtgt acccattctt tcaacccatg
     2401 agcagctcca aatggccaat tttgataaaa aagcgtatat tttccgttaa aaaaagaaaa
     2461 accattagga tcgtttaaca atcctgtttt aggttcgata tgatagctag cacgccaagg
     2521 tgatcgtttt acattatcct taattttatc catctcatct ttagtccaat cagaataagc
     2581 acgatatcgt atttctcgag gtaagttcat attttactcc ttcaatttat ctttttacaa
     2641 ctagtatggt aaacgttttc cgttgaaaaa tcaatcattt catttaaaaa aataaactat
     2701 atgacaaacg tttgacatat ttttaagata tgctaaaata aatttgcatt tcagtgaacc
     2761 gttttcacgt aaaaataaaa aaggagtgat tcgaatgaat tacagtaaag tagcttccga
     2821 cgtaatacaa gcggtcggaa aagataacct tattgcagct gcacactgcg ctacacgtct
     2881 tcgtctcgta ctaaaagatg acacgaaagt gaatcaaaaa gctttagacg aaaatccaga
     2941 tgtgaaaagc acatttaaaa ttaatggaca atatcaagtg attatcggtg caggtgatgt
     3001 taatttcgtt tatgacgaac ttatcaaaaa aactggactt tcggaaattt caacagatga
     3061 tttaaaacaa attgctagta aagataaaaa attcaacccc attatggcat taattaaatt
     3121 attatcagat atttttgttc caattatacc tgcccttgtt gcaggtggtt tattaatggc
     3181 attacaaaac tttttaacag ctgctggact ttttggacca aaatcaattg aagaaatgta
     3241 tcctgcgatt gaaggtattt cctcaatgat ccaactgatg tccgctgcac cattcatgtt
     3301 cttaccaatt ttagtaggta tttcagctgc taaacgtttt ggagcaaacc aatttcttgg
     3361 tgctgcaatt ggtatgatca tgacaacacc agatcttggt ggctcaactg aatattggaa
     3421 tatttttggt tatcatgttt cacaaacaaa ctatgcttat caagttattc cagttttagc
     3481 agctgtttgg atattatcta tattagaaaa attctttcat aaaaaattgc catcatctat
     3541 tgactttaca ttcacgccat tattatcagt aatgattact ggatttttga ctttcacagt
     3601 tattggccct gtaatgttat tgttgtctaa tggaattaca gacattattg tttggctata
     3661 taacactact ggatttattg gaatgggtat ttttggagga acatattcac ttatagtcat
     3721 gactggttta catcaatcat ttccagctat tgaaactcaa ttactttcag cgtggacaaa
     3781 tggtatcgga catggagact ttatctttgt agttgcatct atggcaaacg ttgctcaagg
     3841 tgctgcaaca tttgccattt ggttcttaac taaaaattct aagacaaaaa gtcttgcttc
     3901 ctctgcgggt gtctcagcac ttcttggaat tacagagcct gccttgttcg gagttaactt
     3961 aaaataccgc tttccattct tttgtgcttt aattggttca ggaattgcta cagcagtagc
     4021 aggattactt aaagtagttg ctgtttcact tggttcagca ggtttcttgg gatttctttc
     4081 aattaatgca acatctattc cattttacgt attgtgtgaa ttgattagct ttgtagttgc
     4141 ttttgcaatt acttacttct acggtaaaac aaaagctgct ggtatcttta aagcagaaga
     4201 aattgctgaa caaacaccag ttaattcttc aaaagtagca acaacagatc caatatctac
     4261 tgatgttgaa tcaacacaaa caaaagtttc atcagaaaca attgttagtc ccatttctgg
     4321 taaagtgatt agtctttctt cagtaaatga tccagtcttt tcatcagaag ctatgggaaa
     4381 agggattgcc attaaaccaa atggaaacac ggtccattct ccagtagatg gtactattca
     4441 actcacgttt gaaactggac atgcttatgg tattaaatca aataatggtg ctgaagttct
     4501 aattcatatt ggtattgata ctgtatcaat gggaggaaaa ggatttacac aaaaagttac
     4561 tactaatcaa aaagttagaa aaggcgatat tcttggagca tttgaccgtt caatgattga
     4621 gaaagaaggt cttgatgata caacaatgat tattgtgacc aatacttcgg attattcaga
     4681 agtaaatata gtagctgaaa atacagtcac tgagggtact gatttacttg aaatcaaata
     4741 aatatatttc cctgagtaaa gatggaattt tctttccaaa atcaaataat atagattaat
     4801 caaatatttg agaataacat tttatttaat cttttcatat atcaattgta tgaaaaatta
     4861 ttagaatttt aaaaaatgat aaaaattcaa aaagaaaaaa tagtagttat ttacttgtca
     4921 tgttactaaa taaaaaaata atttaaatat gatatatagt catttattta gtgatttcat
     4981 tctaaaataa agggagaaat gtctatgcta tacggtgcaa ttgaagcagg cggcacaaaa
     5041 tttgtgtgtg ccattggcga tgaagaaatg acgatcaagg aaagagtgag ctttccgaca
     5101 acgacacctg aggaaacaat gcctttagtc attgacttct tcaaacaata ccaagcagat
     5161 ttagcaggga ttgggattgg ctcatttggg cctatcgata tccatcgcga ttccgccact
     5221 tatgggtaca ttacctcgac cccgaaattg gcatggcaaa attttgattt catcggtacc
     5281 atgaaaaaag aatttccgat cccgatttct tggacaacag atgtcaatgc ggctgcctat
     5341 ggtgagtatg tcttcggcag tggcaaagga ttgagcagtg tcgtttacta tacgatcggt
     5401 acgggtgttg gcggcggtgc cttacaagaa gggcgcttta tcgaagggtt tagtcatcca
     5461 gaaatggggc atatgctcgt cgtccctcat ccaaaagatg actttgctgg cagctgtcca
     5521 tttcatggca actgtttaga agggatggcc gctggacccg ccatcgaaaa ccgcttaggg
     5581 aaaaaaggac aagaggttgc agaagatgat ccttattggg aaatcgaagc ctcctatatt
     5641 gctcaatgtg cctacaatac aaccttgatg ttttctccag atgtgatcat ttttggcggt
     5701 ggtgtgatga aacaacgcca tatgctgcaa aacgtccacg acgcatttgc aaaattggtc
     5761 aatgggtatg tcgaaacacc tgagttaagc aaatatatcg tgaccccagc attagaagac
     5821 aacgctggaa cgctcggttg tttggcattg gctcgagaag cggtcttaca ttcataaacg
     5881 aaaaaaggct cttcgacatt tagtgttggt agagaaagat acaactgaaa atttagtcat
     5941 aaccagttag gcagagtgct taactggttt ttgttttact tggaagatca agccttgaat
     6001 gagataaatt cttgctcgaa agttatggaa atttcgatag ccgtaggcca cttgtattgt
     6061 gcaatagttt tttacaaaaa aaagggggtg cggatatttt tttggacctt tttaacaaat
     6121 atatctttgc ttcttc
//
LOCUS       DAFEKH010000101         6132 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.104, whole genome shotgun sequence.
ACCESSION   DAFEKH010000101
VERSION     DAFEKH010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6132
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.104"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(63..1268)
                     /locus_tag="LP386_002789"
     CDS             complement(63..1268)
                     /locus_tag="LP386_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBL1919963.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            complement(1291..1444)
                     /locus_tag="LP386_002790"
                     /pseudo
     CDS             complement(1291..1444)
                     /locus_tag="LP386_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            complement(1447..2832)
                     /locus_tag="LP386_002791"
     CDS             complement(1447..2832)
                     /locus_tag="LP386_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBL1919964.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            complement(2861..3247)
                     /locus_tag="LP386_002792"
     CDS             complement(2861..3247)
                     /locus_tag="LP386_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBL1919965.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            complement(3263..3577)
                     /locus_tag="LP386_002793"
     CDS             complement(3263..3577)
                     /locus_tag="LP386_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBL1919966.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            complement(3930..4409)
                     /gene="rlmH"
                     /locus_tag="LP386_002794"
     CDS             complement(3930..4409)
                     /gene="rlmH"
                     /locus_tag="LP386_002794"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HBL1919967.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYGLAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            4837..6126
                     /locus_tag="LP386_002795"
     CDS             4837..6126
                     /locus_tag="LP386_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBL1919968.1"
                     /translation="MDRKNVTPKMKKNKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVMMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
BASE COUNT         1774 a         1243 c         1154 g         1961 t
ORIGIN      
        1 aggttttgtc caaaattcat aaaaatgttc tcctctctat attcaatgaa tttgtatttg
       61 agttattttt ttgttgttat cacgtcctgt tcttttactg actgttgctt caaaatctgc
      121 ttgtgtcggt ctgtcagttt cgcatggtcg agaatgtctt ttacaacctg cgtctggttg
      181 atttcatcaa gtttaatcgc aacctttaag gtcggggcaa cttgatgaga tagccagttc
      241 agcgtccttt ggaaggagta aggctctggt tttgtggtta gttttaatcg ttcacgattg
      301 ttcccaataa accaagccca ttcttcattc agtttccaat cagaacgagg tttggaatcg
      361 tctttatcta caaaacggat ataccgattg ataattttaa aggcggtatg ctctggattg
      421 tcatagacga gtaaatcacg gactgcataa taggcacgct catttttcaa tcgaatctca
      481 aaacggtttt ttacttctgc gtcttcaatg ggaatatcat ttttcttgta ctgctcgtag
      541 tccttttcat agatacagaa ataaacttca ctttgtaatg aaccgatata gagggtgttt
      601 cccatacatt ccttttcctc tttgcgtacc agttcgccac tgcgatagct tttaaaactg
      661 cggaagacgg agatacattc ttcctgttgg cacttttcag tgagtacagg gatatttaaa
      721 atccctgtct tatcgttaat ggcaaggtca aggcgtttca tcacaccgcc agccaccaaa
      781 acgtccataa agaactcata ccagcttctt tgttgtgcca gaagatagct ttcaaattgt
      841 ctgcacccac gacctttcaa ttccaccaga actcctttgt ccagttcatg ggagcaaagg
      901 acgaatatgt cgcctaaagc ataatgctct gaataagaat agaaaccata gtcctcatga
      961 agaaaatagg acagtttcag ttgtaagatg ttttcgacca cctgctgtac gtctgttgtc
     1021 ggaaagcgaa ttcttacata atcaaacagc atttcaaggg gagcgtcggg attgaagcgt
     1081 tccagagctt cccaaaggga ctgctgtaaa tcctctgatg gcttgacttt tcctgtttca
     1141 atatcgctta gatactgcct tgtaatacca gtcgcaacag ctaaacggtt ttgagatagt
     1201 ccataagcca agcgtttttc ttttaaatgc tgtaaccaag tttgttcatt cagtaaaaat
     1261 ccctccaatc aaaaaggcgt atgtcaactt ttaaagccca tttgacatac gctgaaattt
     1321 tgtaaatccc ttgtaaccaa aggattttct aatgtttttt tgactgtttc ctgtcgattt
     1381 gtacccccct gttagatacc gaggggttaa gtgctggcgt ggctattgcc acaccagcca
     1441 gcaagatcag tccacacctg cgacttccgc ttcgcacgtc gcctgcgtgg actgtctgct
     1501 gttggataac tttttaattt cctccaagaa atcatatcct tttggtacaa ggggagtata
     1561 aaactctgat atgacacttg ttcctacatc aacatagcca cgacctttga ttcgctttaa
     1621 gaagaaatcc ttttgtacgt cactgccaaa catcatgcca tagcccattt cagacatacg
     1681 acctaaagcc actctgaaat taaactgatc acggattccg tcgcctaaat attttgcgtc
     1741 tggacgttga caagccagta ttagaaagaa gccagcttga cgacctaaca tgacaatctg
     1801 tttcagctta ttcataactg cggtgttttc ttttgttccc agcatttcca tgaaagcgac
     1861 gtattcatca aagattaaga agtgtgccgg gagacctaag taagcataat ttttgccagt
     1921 cttatagttc ttcatctgct tcatttcctc actacgtttc atcatttctt catagaatgt
     1981 ttcaatgcaa gaaagcaagt cttcttttct atagtagaca tttgccatca cagaacctaa
     2041 gtccgcaagg tcagcatttt tcgggtcaag aatatacagt tttgaatctg tatgaagcaa
     2101 ggcttcaatc agtgtcagta taaagtaagt tttaccgcca cctgtaccac cagcaatcaa
     2161 catatgaggg agcttatcat attcccacca tacgtttttc attaagcgaa gtttaccatc
     2221 tttagcttct acttcatcaa tagaaatacg actggctatg gtgtcataga gcaaagtata
     2281 ttccacatag gaatccttta actctttatc cgtcagctca cagtacaagc cactctctaa
     2341 tttcttttcc aagtgtaaga gttggtcttg atattttccc agcgtgattt ccacccgtat
     2401 ctgtatcaag ccatttttaa gtcgataata cattttaggg aagtaggtta tcttttcctt
     2461 tgtacgacca gcactatctt taaagaaacc ctctgttttg acctgttcag attcatacca
     2521 cttgttttca agtatcatct ttgccagttt ttgacggtgg taaagttgtt taaccgtatc
     2581 atagcgaacc cgtttgaata caaacgctac cagcaagcag ataagaattg cgacactgaa
     2641 actgataatt aaatagggaa tgtcaatctt atctgcttgt gataggttaa aatcctgcca
     2701 gttgatctgc tggattgtct tcacatgaaa cagtccgaca accagcagga aaacaggcag
     2761 gagtgacgct atcgtaaaat gaaagactaa atctttacca gatgggcgaa tccttttacc
     2821 acgctgtttc atgcgaaaaa gtctcctttc tacctagcga ctatttgtct tgtgtcggtt
     2881 ctttctttgc ttgtggttga gctttgaatg aactagaatc ctttgtcagc acaatatcgt
     2941 ctgccttgat ataccagtca acatctgctc cttgataggt ggcagtagca acggtgtccg
     3001 caatgggatt gataagttcc acccgtgcgt tataatcaaa ctctttcaaa ggcacgctgg
     3061 caggaatact tacttgaatc atgcgtcctt gtcctttgga ttttaagtca taggtacgtt
     3121 ccttgatttc atctgaaacc gacccgtctt cattttggat tctcacttca cgacgtagag
     3181 cagagaattt caattctcca aaagtcgtgt ctttatctaa tacaatgcca tttgctaatc
     3241 tcatcatttt tcctctcttt ctttattctt ttatcatgtc gtcagcatgt aaaaggtaat
     3301 ttgtaaaacc acgagtgccg attttgtagc cctctgcggt aatacgtgga ttgactaact
     3361 tcacacgttc ctcaaagccg aaatgttttt cgccagcttc agcaggaagc accaccacaa
     3421 tatcatctgc tctttgaaca tcagaataga gattatagct tcttgataag acagttagcc
     3481 gtccgttgat tcttcgctga acgactttat cctcgccagc aaattctaaa ttgccgaatg
     3541 ttttttccat gttgggaatc acaaatttaa gttccatatt tttacctatc ctttcttttt
     3601 tattggctga atgaatgttt gatggtctta aagagtgggg aacgaccttt tgattcttga
     3661 ttttttgttt tcataagttc acttcctttc aaaatcgggt aaaaaaatag acacctcatt
     3721 ttttgaagtg tctacctatt aaatattcaa attttattgg aagtatcttt atatcttcac
     3781 ttttcaagga taaatcgtcg tatcaaagct cattcataag tagtaaatta gtagtaaatt
     3841 gagtggtttt gaccttgata aagtgtgata agtccagttt ttatgcggat aactagattt
     3901 ttatgctatt tttctcttaa aaaatatcat tatttgtggt atggagcccc cgcgttgatc
     3961 cggaaggcac ggtagatttg ctcgacgagg atcaggcgca tcaattgatg tggatacgtc
     4021 attttgccaa aagagatctg agcattgctt cttttcatga cggcttcgct gagtcctaaa
     4081 gaaccgccga taacaaaaac aaggtggctt tttccttgga tacctaattg gtcgatttgt
     4141 ttagcaaaag attcgcttgt gggatttttc ccttcaattg ctaagccata gacgtattct
     4201 tgttctttga ttttcgctaa gatccgttct ccttcttttt cttttacttg tctcatttgc
     4261 gcttcgctta aattctccgg ggctttttcg tcaggaactt cgatcaattc gattttcgca
     4321 taggcattca gccgtttgac atactcattg ataccttgga tcaagtattt ttcttttaat
     4381 tttcctactg aaataatttt gatattcatg ttttctctcc tttgatcttc acgctcactt
     4441 tgtttattat aatcaatttt ttcgtctata tgtttatttt gactattttt gttaaaaaga
     4501 tttccccaac agttatgcac aacatccaca ggtttatcca cagaaaacag cgttgtttta
     4561 ccttatttca tcacattcat taggcaaaca tacgttttat aagaatttat ccactttata
     4621 cacaggctgt ggatatgttt tatcccttat ttttccaatc ctatccgcgt agttttacac
     4681 aatatctgtg gaaaaagaaa atcaaatatt ttcatctgaa aacaatgatt tttcctaaag
     4741 tttttcataa aaagttcaaa gtctcaaagt agactaaagt caacaaataa gactatacta
     4801 acagtagata aatgaatgta attggaggag gaacacatgg atagaaaaaa tgtgacacca
     4861 aagatgaaaa aaaataaaaa taatagcctc tggcgtaagt tgggtctggg gcttgttgga
     4921 gggatcgttg gaggactact gacagctggc attttttatg cagcgatggg cactggcaac
     4981 aatagttcta ctgctacaag cggcaatcaa aattctgccg gtgaaacagt tgtggaaaat
     5041 gtcaaagtca atgtagattc tgatatcacc aaagcggtag ataaagttca agacgctgtc
     5101 gtttctgtta tcaacttaca aagtcaaaac caatcaagcg gttttggcgg attattcggg
     5161 cagcaagaag aaagtagcag ctcagatgat agtaatttgg aagcttatag tgaaggaagc
     5221 ggcgtaatct acaaaaaaga cgggaatact gcttatgtag tcacaaacaa tcacgtagta
     5281 gatggacagc aaggtttgga agtcatgatg aaagacggta cgaaggtaaa agctgaatta
     5341 gttggaacag atgcctattc agatttagcg gtgttgaaga tcaattcaga caaagtcgaa
     5401 acggttgcct cttttgggga ctcaagtgct ttgaaggttg gtgaacctgc gattgcgatt
     5461 ggttccccat taggatctga atatgcgaat tctgtcactt caggaatcat ttcttccttg
     5521 aaccgacaag taacaagtac gaatgaatcg aacgaaacag tcaatatcaa tgcgatccaa
     5581 acagatgcag cgatcaaccc gggaaattct ggtggtcctt tagtgaatat cgaaggacaa
     5641 gttatcggta tcaactcaag taagatcgca agtacttctg aatcgacttc taatgtaagc
     5701 gtagaaggaa tgggatttgc catcccaagt aacgatgtag tgaatatcat caaccaactg
     5761 gaaaaagacg gaaaagtgac acgtccagct ctaggtatca caatggtcga cttatctgcc
     5821 gtttctactc agcaacaaga acaaatcttg aagattcctt catctgtaac taacggtgtc
     5881 atcgtgacaa atgtccaaac agctacaccg gcagaaaaag ctgggttgaa acaatacgac
     5941 gtcattacta agatcgatga caaagaagtt tcttctggtg tagaacttca atctgctttg
     6001 tataagaaaa aagtgggaga ttctgtcaaa atcacttact atgaaggctc gaaagaaaaa
     6061 acaactactg ttgaattgac gatcgatcaa tcggcattaa aacaaaatca aaatagtgaa
     6121 aattaataaa aa
//
LOCUS       DAFEKH010000102         6033 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.105, whole genome shotgun sequence.
ACCESSION   DAFEKH010000102
VERSION     DAFEKH010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6033
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.105"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..933
                     /locus_tag="LP386_002796"
     CDS             <1..933
                     /locus_tag="LP386_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL1919969.1"
                     /translation="RWKETLPEISHEINIVNLTSDEKNKGLLDPYVIMKNTKDSESLA
                     IDILTFLTGISSRDGERFPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHI
                     ESFTDYDFAHLLFSDGYVEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAM
                     LIVISTFALDFIHTDRSIFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVT
                     QNTDDLLDEKLKNNLGLKFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCL
                     ISDLYGRVGVIQFHPVFEELLHAFDTRPPVRKEV"
     gene            936..3119
                     /locus_tag="LP386_002797"
     CDS             936..3119
                     /locus_tag="LP386_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBL1919970.1"
                     /translation="MKPSILNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVTPSGLSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHALMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNMTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRM
                     MRKPRMLMHAHMHRLQRKLGRSVTALGAGSAIASATGKKGQSGSGSSASTQADHSRPN
                     GQEKSTLGKRIGQTIGTVADTKDRMVDTAGNLKEQVKDLPTNARYAVYQGKSKVTDNV
                     HDLTRSISQTKADKASGRKKQQEQRRKTIAERRSEMEQVKQKKQPASSVHERPATKQE
                     QSHDGQTSRQTTVQASYRESQQAKQERPTVKSDSSSLKTERQSNTVQERTVQKPVTST
                     APTDRASQRSITKERQSTVQRVPLQNTKSRPPIKTATIKKGSKKP"
     gene            3116..4117
                     /locus_tag="LP386_002798"
     CDS             3116..4117
                     /locus_tag="LP386_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBL1919971.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDGGFSNIHYGGV
                     DVSAEVLAHKPMVEKVAKEYGIEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLGVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGDEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKFEGWKYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTRHIPLLEAKA
                     GDLVFFHSTYNAGSYITHIGIYLGDNRMFHAGDPIGYADLTSSYWQQHLVGAGRIKQ"
     gene            4132..5046
                     /locus_tag="LP386_002799"
     CDS             4132..5046
                     /locus_tag="LP386_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL1919972.1"
                     /translation="MMKFGKNQNTEKQTPKEKKPRVYKVNPRKKVVIVLWVLLGLSFS
                     FAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWELNDKSIDNRIEN
                     LKAYLTEELQALNVDTVRKDIPVSSSVKGFQIWTVEADGDNQFDVTYSVDQLITEGEN
                     TKTVHSAYIVSVYVDSTGNMVLIKNPTITSIPKKSDYKPKAIESEGTVDSITTNEINE
                     FLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIYNRKDNQVTVSLTVEY
                     IDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            5291..5407
                     /locus_tag="LP386_002800"
     CDS             5291..5407
                     /locus_tag="LP386_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HBL1919973.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            5423..>6033
                     /locus_tag="LP386_002801"
     CDS             5423..>6033
                     /locus_tag="LP386_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HBL1919974.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQE"
BASE COUNT         1936 a         1136 c         1277 g         1684 t
ORIGIN      
        1 agatggaaag aaaccttgcc agagatttcc catgaaatca atatcgtcaa tctgacttct
       61 gatgagaaaa acaaaggctt acttgaccct tatgtaatta tgaaaaatac caaagattct
      121 gaatcactgg ctattgatat tttgacattc cttacgggga tttcctctcg tgatggggaa
      181 cgcttcccaa tccttagaaa agccattcgt gcagtaacca atagtgaagt gcgagggttg
      241 atgaaagtga ttgaagaatt acgggttgag aatacgccac taagtaccag catagccgac
      301 catatcgaaa gttttacaga ctatgacttt gcccatctgc tttttagtga tggttatgta
      361 gagcagtcta tcagccttga aaaacaactg aacattatac aggttgccga cttggtactt
      421 cctgacaagg aaacttcctt tgaggaatat accacaatgg agttactatc ggtagcaatg
      481 ctgattgtca ttagtacctt tgcgttggac tttatccata cagaccgaag tattttcaag
      541 attgtagact tagacgaagc atggagcttc ttacaggtgg cacaagggaa aacactatct
      601 atgaagctgg ttcgtgctgg tcgtgctatg aacgctgggg tatatttcgt gacccaaaat
      661 acagatgacc tcttagatga aaaactgaaa aataacctcg gcttaaaatt tgcctttcgt
      721 tccactgacc ttaacgagat taaaaaaacc cttgcctttt ttggtgtaga cccagaggac
      781 gaaaacaatc agaagcgatt gcgtgatttg gaaaacgggc aatgccttat cagtgattta
      841 tatggtcgtg tcggtgtgat acagttccac cctgtatttg aagaactgct ccatgccttt
      901 gataccagac cacctgtgcg aaaagaggtg taaatgtgaa accatcaata ttaaacagaa
      961 taaaatcaaa ctggacgctg aaacgtctag gtaaagtggc aatgacagtg gctttcacac
     1021 ttgtgattgc catttttctt ttagccatgc tgggaacggt ggttcaagct gcgggcttgg
     1081 tagatgatac ggtcaatgtg gcaaatgaat acagccgata cccacttgaa aactatcaac
     1141 tggattttta tgtggataat agctggggct ggctaccgtg gaactggtcg gacggaattg
     1201 gaaaacaagt catgtatgga ctatatgcca ttaccaattt tatttggaca atcagtcttt
     1261 atgtttccaa tgcgacgggt tacttagtac aggaagccta ttccttagac ttcatttccg
     1321 ctacagcaga ttccattggc aagaatatgc agacccttgc aggggttacg cctagtggac
     1381 tatcaacaga gggtttctat gttggattcc ttttactctt gattttggtt cttggggttt
     1441 atgttgccta tacaggactg ataaagagag aaaccacaaa ggcaattcat gccctcatga
     1501 attttgtgct ggtttttatc ctatcggctt cctttattgc ctacgctccc gactacatta
     1561 aaaaaatcaa tgacttttca tcagacatca gcaacgctag tttgtcactg ggtacaaaaa
     1621 ttgtcatgcc ccattcagat agtcaaggca aggacagtgt ggacttgata cgtgacagcc
     1681 tattttccat acaggttcag caaccgtggc tactgcttca atataacagt tcagacattg
     1741 aaagtattgg tattgaccgt gtggaaagcc tgctctcaac cagtccagat tccaacaatg
     1801 gggaagacag agaaaaaatt gttgcggaag aaattgaaga tagaagcaat accaatatga
     1861 cgattacaaa gacgattaac cgtttaggta cagtcttctt cctatttgtc ttcaatattg
     1921 ggatttccat atttgtattc ctattaacag gaatcatgat tttctcgcag gtacttttta
     1981 tcatctatgc tatgtttctg cctgtgagct ttattttaag catgattcca tcatttgatg
     2041 gtatgtcaaa acgagccata acaaagctct ttaataccat tttgacacga gctggaatca
     2101 cattgattat tacgacagca tttagtattt caaccatgct ctatacctta tcggctggtt
     2161 atccgttctt tttgattgct tttctacaga ttgtgacctt tgcaggaatc tactttaagc
     2221 tgggcgattt aatgagtatg ttttctctac agagtaacga ttctcaaagt gtgggaagtc
     2281 gtatgatgag aaaacctcgt atgcttatgc acgctcacat gcaccgtcta cagcggaaac
     2341 ttggacgctc cgtgactgct ttaggggctg ggtctgccat tgccagtgct acgggtaaaa
     2401 aaggacagtc gggttcggga agttctgcga gtacacaagc agatcactct cgaccaaacg
     2461 ggcaggaaaa atcaacacta ggaaagcgta tcggtcaaac catcggtaca gtagctgata
     2521 ccaaagacag aatggtagat actgctggta atttgaaaga acaggttaag gatttgccga
     2581 ccaatgcaag atatgcagta tatcaaggaa aatctaaagt gacggataat gtccatgatt
     2641 taaccagaag tatttctcaa accaaagcgg ataaagccag tggacgcaag aaacagcagg
     2701 aacaaagacg gaaaaccatt gcggagcgtc gctctgaaat ggaacaggtc aaacagaaaa
     2761 aacagccagc ttcttccgtt catgaaagac cagccactaa gcaagaacaa tctcatgatg
     2821 gacagacttc aaggcaaaca actgtacagg cttcctatag ggaatctcaa caagccaaac
     2881 aagagcgtcc aacagttaag tccgattctt caagtttaaa aacggaacgt caaagtaata
     2941 cagttcaaga aagaacggtt caaaagccag taacttcaac tgcaccaaca gatagagctt
     3001 cacaacgttc aatcacaaaa gaacgtcagt ctactgttca aagagtacca ctacaaaata
     3061 caaaaagtag accaccaatc aaaaccgcca ccattaagaa aggcagtaag aaaccatgaa
     3121 gctgaaaact ttagtgattg gtggttcggg attattcttg atggtcttct cactgcttct
     3181 gtttgtcgcc attttatttt cagatgaaca agatggcggt ttttccaaca ttcactatgg
     3241 cggtgtggat gtttccgcag aagtgctggc tcataagcct atggtagaaa aagttgccaa
     3301 agaatatgga attgaagaat acgtcaatat acttcttgcg attatacagg tggaatcggg
     3361 tggtacagca gaagatgtta tgcagtcctc ggaatccctc ggtcttccac ctaattcatt
     3421 gagtacagaa gaatccatta agcaaggtgt gaagtatttc agtgagttat tagccagtag
     3481 cgaaaggctt ggtgtagatt tagaatcggt tatccagtcc tacaattatg gtggtggttt
     3541 cttaggatat gtggctaatc gtgggaataa atataccttt gaactggctc aaagtttctc
     3601 aaaagagtat tcgggtgacg aaaaagtgtc ttaccccaat cccatagcca tacctatcaa
     3661 tgggggctgg cgatacaatt acgggaatat gttttatgtg caactggtaa cgcagtatct
     3721 tgtcacaaca gagtttgatg atgatacagt acaagccatc atggacgaag ctctgaaatt
     3781 tgaaggctgg aagtatgtct atggcggagc ttccccgact acctcttttg attgtagcgg
     3841 actgacacaa tggacgtatg gaaaagctgg aatcaactta ccacgaacag cacaacagca
     3901 atatgatgta acccggcata tcccattatt ggaagcaaaa gccggcgatt tggttttctt
     3961 tcattctacc tataacgctg gctcttatat tactcatatc gggatttatt taggcgataa
     4021 ccgtatgttt catgcaggcg accctatcgg ttatgccgac ttaacaagct cttactggca
     4081 acagcattta gtgggagcag gacgaatcaa acaataagaa aggacgattc aatgatgaaa
     4141 ttcggaaaaa atcagaatac agaaaaacag acaccaaagg aaaagaaacc tcgtgtctat
     4201 aaggtcaatc ctcgtaaaaa ggttgtgatt gtcctatggg tacttttagg acttagtttc
     4261 agctttgcga tattcaagca ctttacagcc attgataccc ataccattca tgaaaccacc
     4321 atcatagaaa aggaatatgt cgatactcat catgtggaaa attttgtaga gaactttgcg
     4381 aaagtctact attcatggga actaaacgac aagtccattg ataatcgcat agaaaacctg
     4441 aaagcatatc tgacagagga acttcaagct ctgaatgtcg atacagttcg taaagatatt
     4501 cctgtatcgt cttctgtaaa aggatttcag atatggacgg tagaagcaga tggcgacaat
     4561 caatttgatg taacctacag tgtagaccaa ctcattacag agggggaaaa tacaaagacc
     4621 gtccactctg cttatatagt gagtgtctat gtagacagta ctggaaatat ggtcctcatt
     4681 aagaatccga ccattactag cataccaaag aaatcagact ataaaccaaa agctattgaa
     4741 agtgagggta cggttgattc cattacaacc aatgaaatca atgagttttt aacgacgttc
     4801 ttcaagctct atcctacagc gacagccagt gaactttcct actatgtgaa tgacgggata
     4861 ttaaaaccaa tcggaaaaga gtacatcttt caagaactgg taaatcctat ttacaatcgt
     4921 aaggataatc aagtcacggt atcgctgaca gtggagtata tcgaccagca gaccaaagca
     4981 acgcaggtat ctcaatttga tttggtactt gaaaagaacg ggagtaattg gaagattata
     5041 gaataacaaa tattggtaca ttattacagc tattttgtaa tcacgtactc tctttgataa
     5101 aaaattggag attcctttac aaatatgctc ttacgtgcta ttatttaagt atctatttaa
     5161 aaggagttaa taaatatgcg gcaaggtatt cttaaataaa ctgtcaattt gatagtggga
     5221 acaaataatt ggatgtcctt ttttaggagg gcttagtttt ttgcacccag tttaagaata
     5281 cctttatcat gtgattctaa agtatccgga gaatatctgt atgctttgta tgcctatggt
     5341 tatgcataaa aatcccagtg ataagagtat ttatcactgg gatttttatg cccttttggg
     5401 cttttgaatg gaggaaaatc acatgaaaat tattaatatt ggagttttag ctcatgttga
     5461 tgcgggaaaa actaccttaa cagaaagctt attatataac agtggagcga ttacagaatt
     5521 aggaagcgtg gacaaaggta caacgaggac ggataatacg cttttagaac gtcagagagg
     5581 aattacaatt cagacaggaa taacctcttt tcagtgggaa aatacgaagg tgaacatcat
     5641 agacacgcca ggacatatgg atttcttagc agaagtatat cgttcattat cagttttaga
     5701 tggggcaatt ctactgattt ctgcaaaaga tggcgtacaa gcacaaactc gtatattatt
     5761 tcatgcactt aggaaaatgg ggattcccac aatctttttt atcaataaga ttgaccaaaa
     5821 tggaattgat ttatcaacgg tttatcagga tattaaagag aaactttctg ccgaaattgt
     5881 aatcaaacag aaggtagaac tgtatcctaa tatgtgtgtg acgaacttta ccgaatctga
     5941 acaatgggat acggtaatag agggaaacga tgacctttta gagaaatata tgtccggtaa
     6001 atcattagaa gcattggaac tcgaacaaga gga
//
LOCUS       DAFEKH010000103         5907 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.107, whole genome shotgun sequence.
ACCESSION   DAFEKH010000103
VERSION     DAFEKH010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5907
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.107"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            91..309
                     /locus_tag="LP386_002802"
     CDS             91..309
                     /locus_tag="LP386_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919975.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(598..1110)
                     /locus_tag="LP386_002803"
     CDS             complement(598..1110)
                     /locus_tag="LP386_002803"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBL1919976.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(1124..3421)
                     /gene="recJ"
                     /locus_tag="LP386_002804"
     CDS             complement(1124..3421)
                     /gene="recJ"
                     /locus_tag="LP386_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HBL1919977.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(3563..4006)
                     /locus_tag="LP386_002805"
     CDS             complement(3563..4006)
                     /locus_tag="LP386_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HBL1919978.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(4007..4795)
                     /locus_tag="LP386_002806"
     CDS             complement(4007..4795)
                     /locus_tag="LP386_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL1919979.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(4792..5733)
                     /locus_tag="LP386_002807"
     CDS             complement(4792..5733)
                     /locus_tag="LP386_002807"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HBL1919980.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
BASE COUNT         1626 a         1323 c         1025 g         1933 t
ORIGIN      
        1 ttttatcact tccctcttta caaaccgaac aaatattcgt atactaaata tacgaacaat
       61 tgttcgcata aattaaagag gtgagaattc atgaaatcaa tgagacgtct tggcttagta
      121 ttaactgttt tgtttttagg tattattatt ggtaatttcg gcatacgtcc agctttactt
      181 gtgtttgttc cgttatttac tttgtggttc atgttgtggg atgaaaagaa gtaccgtcaa
      241 tctgagcggc gcagaattca tgaagatcat ttctatcatg agccctacta cagatccagg
      301 caatcataat aaggattgac tgctaattat tcaaaagaca agaagttaaa cttttacggg
      361 ggtgtgacaa aaatcggtca catccttttt ttcgaataaa cggtgttcta aagccagttt
      421 ttcggtatta agtcaaattg cggaaaaagt gattttttaa acttctactg gtctttgctt
      481 gtttccattt ataaaaaaat agcgaccctc aaaagtcaga tagagaatct gacttttgag
      541 ggtcgcttta aaatcgcttc tttaagaata acatcaagaa tagcttcttt tttctgctta
      601 atattccatt aatgtaatga tgtcatatcc tttgattttg tcgcgtccat ggagatccat
      661 caattcgatc aaaaatgcgc agcctacgac tacaccgcct aattgttcga tcagttcgat
      721 cgtcgctttg attgttcctc cagtagctag caaatcgtca caaatcagca cacgttgacc
      781 tggtttaatg gcatccttat gcaatgtcaa tgtatctgtt ccatattcta atccataagt
      841 cacttcgatg gtttctcgag gtaacttccc ttttttgcgg actggggcaa aaccgactcc
      901 taactcataa gcaacaggac atcctacgat gaatccacgg gcttctggcc caactaccat
      961 atcaattcgt ttttcttttg cataatttac gatttgttta gtagcttccc gataagcgtc
     1021 accatctgcc atcagtgggg aaatatctcg aaacacaatt ccttttgacg gatagtcggg
     1081 aatactggca atataatctt ttaaatccac tctttgtttc ctcctaggtt gttaaccatt
     1141 tctttatggt aggaatatcg ctcaaaagca aaaattcctc aactttgatt ttattgagcc
     1201 gtcgctggta taatctgctc tcagtcaaag gatgactttc tgggctagcg actttttgta
     1261 aaacaccgtt ctctattgta acaaatttca attcaaaaaa cacctgtatc ataaaaatta
     1321 ataatttttc agggatacgc aaatattgag ctattgcttt tattttatga cgtatatcaa
     1381 ttcgttcttg agaatggatc aatttaaaca attttgcgta ctgttctctt gtgcctaccc
     1441 cattcaaata ggcctcatca ggtgaaatcc ccatcagata aacacgattg aatgaataag
     1501 accgaaaaac ttctttcaga tccgctaaat catctggaca atccataaca actagagagt
     1561 ttggttttct tttttcaatt attgccttta cagaatctag tccttcgaaa acaatcgcag
     1621 cttcctggat aatctcaggc acgaatttca acgtcgaaga atcaaatgct aaataaaggc
     1681 taccttccga cgttcggctc tgttcacgga aacgttttgc ccgccaatca aatacttgca
     1741 gaccacccac agaaaaatca gataccatca gctgcggttt cttacgcccg ttccattcat
     1801 tgatcgaaag ctttcctacc acatctacct gattattcag cagttcttct tcttgagtac
     1861 caaaaccaaa agcgaccgca tcaagctgac tcgatgcatc ggaaaggaca aatttcagat
     1921 gctgttggtt tgctccgatt cttttgatat tttctgcttg gacttgtcga aataaaaact
     1981 gaggcaaagg attatccgta ccaaatggcg ccaatagttt cagctcatca attcgctcta
     2041 ctgttacttc atttggcagc aatacttcat caattctcaa ctcaggccct ctcatcaagt
     2101 caatttgatg atcgactata tattggttca tcttctcctg tagtatagtg acattttcac
     2161 ttggcatcgt taaaccgact gctgcatgat gtcctccgaa gtaagtaaat aaatctcgca
     2221 tctggtcaag catttcaaaa agattcaagg cttcaatact acgtccagat cctttagctg
     2281 atccatcttc ttttaaagta aggacaagcg ttggtttacc cgtttcattc attattttcc
     2341 cagcaacaat gcccaaaacg ccttcatgcc atcctcggtt taccaataga tggatatgat
     2401 tctccttatt gaccatcgct aatgcttctt gtgttatctg ctctacgatt gcttttcttt
     2461 cttcattgat ctcattcaat ttttttgctt gaacggatgc ttcctcttca tcaaacgtcg
     2521 caagtaacga gacggcagga cgtggatcgc ccatccgacc gattgcattt agtctgggag
     2581 caatcgaaaa accgatcgtt gtttcgtctg cgtccctcat ttttacgccg ctttcttcaa
     2641 atagcgcctg aagtcctatc cgttctgaat gatgaatggc atcgattcct aatgaaacaa
     2701 ggattcgatt ctcatcagtc aatgaaacta aatcggcgat cgttcctatc gctactaaat
     2761 ccaaaaattc tgcaggcggt tcttccaata atgcagaagc tactttgaat gctactccga
     2821 ctcctgccaa atctggaaat ggatagtgcc ccgctggatg acgagggtga acaatcgcat
     2881 aagcgtctgg taaattctca ggtagttcgt gatgatctgt aatgatcacg tctacaccag
     2941 cttgctgagc gtatgctacc gcatcatttc ctgctacccc gttatcaaca gtgatgatca
     3001 actggattcc ttcttcgatc ttttcttggt ataccgattg gtttggtcca tacccatgct
     3061 caaatcgatt tggcaggaat acttctactt ctgcaccaag taattccagt gtttctttca
     3121 ttaccgttgc actggtgatc ccatctgcgt cataatcacc gtaaacgagg attttttctc
     3181 cactgattac agcttcttgg attcggctga ttgctttatc catatcgtgt atcagatacg
     3241 gatcatgtaa ttcttgttcc tttggatgta aaaatcggtt gatatccttt tcctcatggt
     3301 aacctctttg ccacagtaac ttaccgacaa atggagataa tttcagttca cggatcattt
     3361 ggagaaagga ttcagaaggc tctgtctcgc ttaacttcca atcaaaattt gcttgtctca
     3421 ctttctcact cctaacttag ttattatagc aaaggaaatc agcaaaaaaa agcagaaaga
     3481 aagaataaaa acagatcaga tccgctagac agatgttcag caggacctga tcttttgtac
     3541 gaccatttat gaaatatccc tattagtcaa aataattgaa gctttgtttg ggcgattgag
     3601 ttttttgttc ttccggcgct ttcaattgac tgatttgtgc ggttttcgct tgtaactccg
     3661 cctgataagc agcttccaac tccgcacgtt cgtttctaaa ctcgcgttgc tgttcttctt
     3721 ttgcttcttc aattttcttt tgaagttctg tttgatattc tgacatttcc tgagtcagct
     3781 gtttgatttg ctttttttgc tgccatagtg ttgccgaagc agtcaaaaat acaatcagtg
     3841 caccaatcag cgcagaaccg atgatcacta agatcaatgg cgcagaaaag gaagtgaagc
     3901 caaaacttac aggaacattt ttattgttca atacagcaaa aagaacaata atcaaaacta
     3961 aaacaaatcc aagaatcaca ttgctttgct ttttcaattc cttcacctac tttttgttaa
     4021 aaattccgct ggctaaataa tcaccaatcg ttggaaacag cgtataaaat tttgatgcaa
     4081 cttctaaaat aaacggttga ttgatttccc gttttggatg tctcatattg cggacgatca
     4141 tttttgccaa cttggcaggt tctaaaacga tttgtccgac tttttccaaa tagcttccgc
     4201 ttggatcagc cttatcgaag aaatttgtct cgattggacc tggattcact gtcgtaacag
     4261 ctacgccaag tggtttcaat tctaatcgca aagcgttgga gaagccaagg actgcaaatt
     4321 tcgtggcaga ataaaccgtt gattttgcag ttgccatttt tccagccata gaggcgatat
     4381 taatgatatg accttgtctt ctttctgcca tatcgatcgc aaatttttgt gtcaaaacca
     4441 tcattcctaa gatgttgact tcaaacatat cgtatgcttt tccaaggtcg aatgtaagga
     4501 agtcttcgaa aatcccaaaa cccgcattgt ttaccagaat atcgacgcgc ccgacttctt
     4561 ccatcacctt ttcatataat tcgtccacgc tttcaggatt gctgacgtct accttgaaag
     4621 cataagcctc tttgccgctc aagcgtctgc actcgtctct gacaccttct acaaatgcca
     4681 ttcttcgtgc gcaacttata acgattgctc cttgctttgc tgcttcataa cagatttgtg
     4741 cgcccagacc gcctgaacta cctgttacta aaacaacttt atcttctaaa ttcatgcctc
     4801 ttcctcctcg cgaaatggaa tctcaatgct atcaaaatct ttcataatcg tcgtgttttc
     4861 aaacacttct tgtgcttctt tttcaagctc taaagctgct tttcctaaat atctcgcact
     4921 gatatgagta agtagcagcc gttttgcctg cgcttctttt gcaacttcag cagcttgatg
     4981 agtcgtggaa tggaaatagt tgtgcgccat tcttgcttca tctttattaa atgtgctttc
     5041 atgtaccaga atatcgctat tttccgcaag cacaacggaa ttatgtgttt ttctcgtatc
     5101 gcctaaaata gtcacgattc gtcctttttt atctggacct acgaaatctt ttccattgat
     5161 cgtccgccca tcttctagtt ggatcgtttc accttgcttc agtttgccgt acagtggtcc
     5221 agctggaata cctaattctt ttagacgatc cacctgcaat tctcctttat gatcatgttc
     5281 aaccacacga taaccaaaac tgtcgatccc atgatttagt ttttttgtat aaacagaaaa
     5341 ttgctgatca gtaaaaatcg gggctgtttc atttagctca atgaatttca gcggataact
     5401 taaacgcgtt tgcgaaatac ctaaagagac ttttatgtat tcctctatcc cttttggccc
     5461 gtaaatctct aatggcgtat ccccaccttg aaatgaccgg ctgctgatga gcccgggaag
     5521 tccaaaaata tgatcgccgt gtaaatgtgt aatgaaaatt ttaccgattt ttctcggacg
     5581 aatagtcgtt cgcaaaatct gcatttgcgt gccttcgcca cagtcgaaca accaaacttc
     5641 attgcgctcg tctaaaagtt tcaatgctat acttgtcaca tttctatgtt ttgcaggaac
     5701 acctgcacct gttcctaaaa attgtaattc cataatctac ctgactttct ttaagttcct
     5761 ctttaatttt agggtaaaaa gaagggataa tcaaccgtaa gtcgagaatg ggttcaaatt
     5821 aaaaataacg ttctaaagcg atagcgtttt ctttgaaaat tactataaaa acagcagcga
     5881 acccgtttga gatcctctgc tgttttt
//
LOCUS       DAFEKH010000104         5878 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.108, whole genome shotgun sequence.
ACCESSION   DAFEKH010000104
VERSION     DAFEKH010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5878)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5878)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5878
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.108"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            642..1376
                     /locus_tag="LP386_002808"
     CDS             642..1376
                     /locus_tag="LP386_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL1919981.1"
                     /translation="MQNTFQSKSLYYQLVEILKQRIENSMVAHDKLPSERELTSFYGV
                     SRTTVRLALQELEKMGYIYRQHGKGTFVSELRTNATDLAGAYSFTEQMRAMGKHPETK
                     ILAFKKIEATKYLASHLNVQLGEPLFQLDRLRLADDLPMMIEKSYLPVKLFMSLSQEI
                     LFLKPLYNLFSENFNQIVRLADEEFYASIVQKEDSELLNIPEGSPVLHLVRSTYNLEN
                     EVIEFTLSVARADKFHYKIRHLRSTN"
     gene            1392..2561
                     /locus_tag="LP386_002809"
     CDS             1392..2561
                     /locus_tag="LP386_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL1919982.1"
                     /translation="MFMFSKEELRKLGAENTTREIRQQPELWHETFDRYQETVADLDR
                     LFTDAKQHAGERPIRVIFTGAGTSQYVGDTLIPFLTSQGNTNQFIFQSIGSTDIVATP
                     KEYLIPDETTILVSFARSGNSPESLAAVKMANQLVNKIYHIVITCAPDGLLATQMPTK
                     KENLVLLMPNKANDAGFAMTSSFSCMTLTALLIFDQASNQQKERYVHQLSRLGEEVIQ
                     RESEIQGYLASDFHRIIYLGSGSLGGLTREAQLKVLELTAGKIATVFDTSLGFRHGPK
                     SFVNEQTLVFLFVSNDSYTQKYDVDMLEEIKNDGIAQRVVGIGQKGSLFSGDSFELVA
                     DSLLPDGYLALADIMVAQTIALLCSVKVGNTPDTPSPSGTVNRVVKGVTIYPYEK"
     gene            2577..3572
                     /gene="lacD"
                     /locus_tag="LP386_002810"
     CDS             2577..3572
                     /gene="lacD"
                     /locus_tag="LP386_002810"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBL1919983.1"
                     /translation="MLEWSENKRQAMERLSTPEGIITALAIDQRGALKKMMSALGMEA
                     TKEKIEQFKTLISQELTPYASAILLDPEYGLPAAQKRAAASGLLLAYEKTGYDQTVPG
                     RLPDLLSDCSVLRLKELGADAVKFLLYYDYAEAEEINRQKQVFVERIGSECMAEGLPF
                     YLELLSYDAKNVDTKSLSYAKAKPRKVIEMMKEFSKTQYKVDVLKVEVPVNMSFVEGN
                     ATGEIAYTRQEAAAYFKEQSDATDLPYIFLSAGVSAALFMETLRFAKHAGARFNGVLC
                     GRATWKDAVAPFVEKGEAATLEWLTEQGTQNIRQLNEVIRETAIPWYEKVSESTC"
     gene            3651..4577
                     /locus_tag="LP386_002811"
     CDS             3651..4577
                     /locus_tag="LP386_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HBL1919984.1"
                     /translation="MNKRLLDYSASDFLKAKPMELKQAILASEGRTIMAENVPSSCPY
                     MGKSVTNAELERAAGADLILFNALDLFNPQISGVPLTLKENPIIWIKKALGRAIGVNL
                     EPVDKEVLMSENRTEISSGRIVSPETLKKANELGFNFICLTGNPGTGVSNRTIEKAIT
                     LSKSIFNGLIIAGKMHGAGVDEPIMNLDIAKRFIKTGVDILLVPAPYTVPYFMESDLR
                     GIVDYIKDFNRNKSIEEKVLVLTANGTSQDSSDQETIKKIALASKACGADIQHIGDSL
                     NGICLPENIFALGQAIRGYRHQIIMLGKSNYR"
     gene            4596..5846
                     /locus_tag="LP386_002812"
     CDS             4596..5846
                     /locus_tag="LP386_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL1919985.1"
                     /translation="MIDKVQKIAAKISNQRHLLALRDSMAAVMPLIIIGSFFMLLANF
                     PIEGFTKWLSEIGVQSFLNKASDSTFGIIGLAVTYSLGHNLAKTYGVDSLSAGLLSLS
                     GYVLLTPLLDADGSIGFPTKYFGTSGLFVGIIVALVSTEIFRWFVLKNITIKMPASVP
                     PNVSRAFVAIIPGFFVVLLWFIVVVICYKLGIENVHALIADTLAKPLSLLTKTLPGII
                     LVILIQCFFWMFGIHGAQVTGPIIEPLLLQNSDVNRIAYQAGKELPNIITYEFLYNFV
                     FSGGAGCLFALAILTFFFSKSQENKTLGKLSIAPVSFQVAEPLLFGFPTILNIKMLIP
                     FVTAPVVTTLITYFSMSMGLVAKPVGATIPWTTPPIIAGFLASGGRISGAVIQVITIA
                     INVLIYYPFFKLDDNAKLKSEKND"
BASE COUNT         1968 a          956 c         1203 g         1751 t
ORIGIN      
        1 agtttgaaaa atgctatttc gaggtagaag gatattatat aagcacggtt gactaaacga
       61 agtgataata aaaaaagtta ttcaagaata agaaaaatta tgatacgaat tcagataaac
      121 tggagaatac agagaccttt aaaagggata agaaacaaca taaattcctc ttaagagaga
      181 acgaaaggac aaagccagca acttgataca cgagctagta ttagaggaat ttattctcat
      241 agactccctt ttgaatacgt ttcaacttta attttcatgt tcataaatga tttgaaacca
      301 aagcaaatgc gttgcacttt tcctccgtct tccgaaaatc gttcaattca ctggtaagta
      361 gtcatttgat agtttgaggc aaattgttga ttgatgaagg gtaggagcta aaaaaagata
      421 ccagttgaag agagaaaaag aaaaaaatag agggtgttct tgaatgaaaa aagttggaaa
      481 attatttttc atttcctttt attcctatta aagtcagtga tgtcaatcat attaacaaga
      541 ctaaaaatga aaataaaaaa aagattgttc ttagtattga ctcataaaaa ataccactac
      601 tatacttaca ttgtggttat agccagttag gagagacatc gatgcaaaat acctttcaat
      661 caaaatcact ttattatcag ctggtagaaa tattgaaaca acgaatcgaa aacagtatgg
      721 tcgctcatga caagctgcca tcagaaagag agttgaccag tttttatggc gttagtcgca
      781 cgacggtgcg actagcattg caagaactgg aaaaaatggg ctacatttat cgacaacatg
      841 gaaaaggaac ctttgtttcg gaattaagga caaatgcgac tgatctagct ggcgcatata
      901 gttttaccga acaaatgcgg gcaatgggca aacatcctga aaccaagata ttggccttca
      961 agaagattga agcaactaaa tatttagcga gtcatctgaa tgttcaacta ggtgagcctt
     1021 tatttcaatt agaccgattg cgcttagctg atgatttgcc aatgatgatc gagaaatcct
     1081 atttgccagt gaagctattt atgtcccttt ctcaagaaat tctatttctg aaacctttat
     1141 ataatttgtt ttcagagaat ttcaatcaaa tcgtacggtt ggctgacgag gaattttatg
     1201 ccagcattgt ccagaaagaa gatagtgagt tgctaaatat tccagaagga tcaccagtgc
     1261 tccatttagt tcgctcaacc tataatctcg agaacgaagt gattgaattt acattaagtg
     1321 tagcgcgggc tgataaattt cattataaga tcaggcatct gcgttccact aactgaattg
     1381 gaggaaagaa aatgtttatg ttctcaaaag aagaactacg aaagctagga gcagaaaata
     1441 ctacccgaga aattcgacaa caaccggaac tgtggcatga gacgtttgac cgttatcaag
     1501 aaacagttgc agatttagat cgtttgttta cggatgcgaa acaacatgct ggagagcgac
     1561 caatccgagt catttttaca ggggccggaa cctcgcaata tgtgggagat acactaattc
     1621 cgtttcttac tagtcaagga aatacgaacc agtttatttt tcaaagtatt ggttcgaccg
     1681 atatcgttgc tacgccaaaa gaatacctga ttcctgatga gacaacgatc ttggtctcat
     1741 ttgcccgtag tggaaatagt ccagaaagtc tagccgcagt taagatggcc aatcagctgg
     1801 tcaacaagat ctatcatatc gtgatcacct gtgcaccaga cggattattg gctacacaaa
     1861 tgcctacaaa aaaagaaaat ctagttttac taatgccaaa caaagccaat gacgctggtt
     1921 ttgctatgac aagcagtttc agctgtatga cgctgactgc gctacttatt tttgatcaag
     1981 caagcaatca gcaaaaagaa agatatgttc atcaattaag ccgactagga gaagaagtca
     2041 tccaacgaga atcagagatc caagggtatc tggcatcaga ctttcatcgc atcatttact
     2101 taggttcggg aagcttaggc ggattgacta gagaagcgca attaaaagtt ctcgagttaa
     2161 ctgctggaaa aatcgcaacc gtatttgata catctttagg attcagacat ggtcccaaat
     2221 cttttgtcaa tgagcaaaca ttggttttcc tgtttgtcag caatgactca tatacgcaga
     2281 aatacgatgt agacatgctg gaagaaatca aaaatgacgg tattgcccaa cgcgttgttg
     2341 gaattggtca aaagggttca ttgtttagtg gtgattcctt tgaattagtt gcagattcgt
     2401 tactgccgga tggctatctt gctttagcag atatcatggt agcccaaacg atcgcattac
     2461 tttgttcggt gaaggttggt aatacaccag atacaccatc gccaagtgga acagtcaatc
     2521 gtgtggtcaa aggcgtaacg atttatccat atgaaaaata ggaaagagtg tgaagcatgt
     2581 tagaatggtc ggaaaataaa agacaagcaa tggaacgtct atcgacgcca gaaggcatta
     2641 ttaccgcttt ggcgatcgat cagcgaggcg cgctgaagaa aatgatgtcg gctttaggga
     2701 tggaagcgac aaaggaaaaa attgagcagt ttaaaacact aatttcccaa gaattgactc
     2761 cttatgcctc agcaatttta ttggatcctg aatacggact gcctgctgca cagaagcgtg
     2821 cagcagcgag cggtctgctg ttggcatatg aaaaaactgg ttatgatcaa accgtacccg
     2881 gccgcttgcc ggatctgctg tcggactgtt cagttctgcg attgaaagag ttaggtgcgg
     2941 atgcggtgaa atttttactg tattacgatt atgcagaagc agaggaaatc aatcggcaaa
     3001 agcaagtttt tgttgaacga attggaagcg aatgcatggc tgaaggactg ccattttatt
     3061 tagagttatt gtcatatgat gctaaaaatg tagatacgaa atcgctttcc tatgccaaag
     3121 caaaaccgcg caaagtgatc gaaatgatga aagaattctc gaaaacccag tataaagtag
     3181 atgtcttaaa ggttgaagta ccagtaaaca tgtcatttgt tgaaggaaat gcaacagggg
     3241 agatcgccta tacacgtcaa gaagctgccg cttattttaa agaacaaagc gatgcaacag
     3301 atttgccgta tatcttctta agtgctgggg tatcagcggc attattcatg gagacattgc
     3361 gttttgccaa acatgctggg gcacgattca acggtgtact ctgtggcaga gcaacttgga
     3421 aagatgcagt cgctcctttc gttgaaaaag gagaagcggc aactttagaa tggctgacag
     3481 aacaagggac acaaaacatt cgtcaattga atgaagtgat aagagaaact gccatcccat
     3541 ggtatgagaa agtaagtgaa agcacttgtt aatgtttcta atatattagt agtgataaga
     3601 gatatgtgtg attataattt atcattattg aaactgggag gatattttat atgaataaaa
     3661 gattgttaga ttattcagct tcagattttt tgaaagctaa gccgatggaa ttaaagcagg
     3721 caattttggc ttctgaaggt agaacaatta tggcagaaaa tgtgccaagt agctgtcctt
     3781 acatgggaaa atcagtgaca aatgcagaat tggagagagc tgctggagct gatttaattt
     3841 tgtttaatgc actagatctt tttaatcctc aaatttcagg tgtaccttta actctaaaag
     3901 agaatccaat aatctggatt aaaaaagctt taggaagagc tattggtgta aatttagaac
     3961 ctgtagacaa agaagttttg atgagtgaaa atcgaactga aatttcaagt ggtagaatcg
     4021 tttctcctga gactttaaaa aaggcaaatg aattaggctt taattttatt tgtttaactg
     4081 gaaatccagg aacaggagta tctaatagaa ctattgagaa agcaataaca ttatccaaat
     4141 caatttttaa tggattaatt atcgctggaa aaatgcatgg tgctggtgtt gatgaaccaa
     4201 ttatgaactt agatatagca aaaagattta ttaaaacagg tgtagatatt ttattagttc
     4261 ctgctccata cactgttccg tatttcatgg aaagtgattt gcgaggaatc gttgattata
     4321 taaaagattt taatagaaat aaatctattg aggaaaaagt tctagtacta acggctaatg
     4381 gaacaagcca agactcttct gaccaagaaa ctattaaaaa aattgcatta gcatcaaaag
     4441 catgtggagc tgatattcaa cacatagggg attctttaaa tggtatttgt cttccagaaa
     4501 atatttttgc tttgggtcaa gcaattcggg gatatcgtca tcaaattatt atgttaggaa
     4561 aatctaatta tcgttaatta aggaggaaat gaaagatgat cgacaaagtt caaaaaatag
     4621 ctgcaaaaat tagtaatcaa agacatctac tagctttaag agacagcatg gctgcagtta
     4681 tgccattaat cattattggt tcctttttta tgttattagc aaatttcccg atagaaggat
     4741 ttacaaaatg gttatctgaa attggagtac aatccttttt gaacaaagca tcagattcaa
     4801 catttggtat tattggatta gctgttacct actctttggg acacaatcta gcaaagactt
     4861 atggtgtaga ctcattatca gcaggattat tatctttgag tggatatgtt ttacttacac
     4921 ctttattgga tgcagatggt tctataggat ttccaacaaa atactttggt acctcgggtc
     4981 tttttgttgg tattattgta gcacttgtat ctacagaaat tttccggtgg tttgtactta
     5041 aaaatattac aattaaaatg ccggcaagcg ttccaccaaa tgtaagccga gctttcgttg
     5101 ctattattcc tggctttttt gtcgttctac tatggtttat tgttgttgta atttgttata
     5161 aacttggaat tgaaaatgtt catgctctta ttgcagatac actcgcaaaa ccactatctt
     5221 tactgacgaa aactttacca ggaattatat tggttatact tattcaatgt ttcttttgga
     5281 tgtttggtat tcatggtgca caggtaacgg ggccaataat tgaaccgtta ttattgcaaa
     5341 actctgatgt aaatagaatt gcttatcaag ctggaaaaga acttcctaac attataactt
     5401 atgaattctt atataacttt gttttttctg gtggtgcagg ttgtttattt gcacttgcca
     5461 ttttaacatt tttcttttca aagagtcagg aaaataaaac tttaggtaag ttatcaatcg
     5521 ctccagtaag ttttcaagta gcagagcccc ttctatttgg gtttccaact atattaaata
     5581 taaaaatgtt aattccattt gtaactgcac cagtagtaac aacattaatt acttattttt
     5641 caatgagtat gggattagtt gcaaaacctg taggagcaac aatcccatgg acaactccac
     5701 cgataattgc cggattttta gcttctggtg gacgaataag tggtgcagtg attcaagtaa
     5761 taacaattgc aataaatgtt ttgatatact atccattctt taaattagat gataatgcca
     5821 agctaaaaag cgaaaaaaat gattagaact acctatatgt ttctaactgt agttaagt
//
LOCUS       DAFEKH010000105         5702 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.109, whole genome shotgun sequence.
ACCESSION   DAFEKH010000105
VERSION     DAFEKH010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5702
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.109"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..340)
                     /locus_tag="LP386_002813"
     CDS             complement(<1..340)
                     /locus_tag="LP386_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1919986.1"
                     /translation="MMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFEFIYPIV
                     EATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDTNVAYRWFLGYSFEEKIP
                     HFSTFGKNYVR"
     gene            complement(1671..2336)
                     /locus_tag="LP386_002814"
     CDS             complement(1671..2336)
                     /locus_tag="LP386_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1919987.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            2516..4498
                     /locus_tag="LP386_002815"
     CDS             2516..4498
                     /locus_tag="LP386_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HBL1919988.1"
                     /translation="MSGFALVSINKQVLYRTNEFFHQTDTYTPIRLPQHFIGQEEYEQ
                     LIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLEMTLYYQGDVKSSHEKVPY
                     SNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLFTDRFNQAFHTDYATNIFE
                     DFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNDFSLHQV
                     LWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGIYGISLISLLLVE
                     KIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFSSSQLAVSHEPPKEIAGED
                     YHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSILVNVSDYLNEENEQFGRG
                     IKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQEIS
                     EKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSMYLERNILSGEIYPPLKIK
                     IGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFSFF
                     LLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIEREP
                     KYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            4502..5140
                     /locus_tag="LP386_002816"
     CDS             4502..5140
                     /locus_tag="LP386_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1919989.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            5168..5596
                     /locus_tag="LP386_002817"
     CDS             5168..5596
                     /locus_tag="LP386_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919990.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
BASE COUNT         1881 a          879 c         1045 g         1897 t
ORIGIN      
        1 ggcgaacata attctttcca aaagttgaga aatgggggat tttctcctcg aaggagtagc
       61 ctaagaacca gcggtaagcg acattggtat cgacttcctt aatggtttgt cgcatggaac
      121 ggataccgaa taaatactga ataaacacca atttgatcag aatcactgga tcgatacttg
      181 ggcgacctaa atcggagtaa gtggcttcga cgattggata aataaattca aaatcaagcg
      241 cggcatcaat ctttcgaacg agatgatctt gaggaactag atcatcaatc gtaagcatcg
      301 caaattgatt tctaccattc gtattgtttt tagacatcat agctatcact ccttgcattc
      361 gttttcataa atctattata aaagaaaaga ctgtagatat catccataaa atggactttg
      421 tctacagtct gaggactacc tgtattagtc ctcttttttg accagatttt gaccagtcta
      481 ttttacattc taatatattc atatgagcta attttatgat taaatggtaa gtgtttcctt
      541 gtttgtttta gtttaaacta gtgtgtaatt taaaaatcta tatggaaggg tctgtggggt
      601 aatacttaaa taaaggctag gaacctgata acatcaaggt tcctagcctt tttataataa
      661 aatgaagcga aaataatttc ttttaaagag ccgagattat cagctatata agagtgaatt
      721 tgatgcaaaa aacagagccg aaacagtctt ggtgttcgta gctctgctta tatgtttcga
      781 atttaagaca aagagttggc aaaagatgtt gataaggaag ataagataac tgtgttatat
      841 aaactaggta actaactgta acaagctaat tttaagagat tcttattaga agacgtttag
      901 gaatataact aagaaaatga ttatacaggt aattgtcatt tcaataatgt tttctaattt
      961 tcgcgtcttt gttttaagaa aaaggccaga atcagttgga aaaaagttcg tacgatagtg
     1021 aagaggggca aaatttccta ctaatattcc cactaacaag agataaaacg gccaggttgg
     1081 tgtgattcct ctataaaaaa atgcccatgc taccgaaatc ccatagatta acaactgaac
     1141 aatttttaca atgaaaaaat tgttctgcca ttactcaaag tctcttcctc cttgtatcgt
     1201 ttatttgttt cattttatca ttatgatagg cgcttgaaca atccattttg tattttattg
     1261 agtactcttg gataaactac cagcgattat catatttatt tatgttactg taagccatca
     1321 tataaaagta aatgagcaga tcatagaaat ataaaaaaga actaaaattg atctaaatta
     1381 tgtgcagctt gactacgtac caatctatat tacttactag attggtcgtt aatctattcg
     1441 gatcgaatga gcaaaatatt tttgtgaatg tccatccttg attatgattc caaaaagaat
     1501 cattgggagg ctgtggcgta aatattatac tataagccag aaatacctat cattctgaac
     1561 ttttttattt aggaactttc atctcaaggc tttttcaatt aatttgtacc cctgtttttt
     1621 ggataagatc atgtgcattg attttttcta tctctacgtt catctcctac ttaatgccta
     1681 tctggctcct gagggcttct ttttaaggcg tcgtcatagt cttggctgag gatttcttgg
     1741 taatctgagg gaatggcttc ccaagtgagc aggcgaacgt tcatgacgtg ttttcctttg
     1801 tgtttgatta cagcatggtt tttctctttt tctacctctc cagcgtgaaa agacagccat
     1861 gtaccatggc caaagatatc attacatacc caacgttcga tggaattgtc cacgtatcct
     1921 acagggagtg tggtatagcc gatttgtggt ttcaaaaaag gattgaatcg atcgatcgtt
     1981 tcatttttgt attgataatt gataagaaaa agatagacca aacaaaagac gagcagaaag
     2041 aaagatagtg tctttttgag tgagaagggt tgttttgatg aataagattt cttgttaaca
     2101 agaggttcat ctggcaatgt tggttctatt gattcggtag ctgattcaat agaaggaaaa
     2161 tcaatcggca gacctaaagt atgatgtaaa agtgacagca tttcaaggtc tggcattgta
     2221 cgagaatttt cccaactaga aatcgtttta tcggaaacac caattttttc gcctaattct
     2281 ttttgcgtaa gcttacaatt tctgcggtaa gttcgtattt tttctccggt gttcatcttc
     2341 ttctcctttc gattctacag tatatagatt tattctacat gacctataca cttgatagat
     2401 acgttttttt gatgaaaaac ggtatgattt tatcaaagaa tcatttaagt aagggagagt
     2461 ggtgataatc aaaaaaaagt tcacagtttt actcacaatc atagtgaccg gtatcatgag
     2521 tggttttgcc ttggttagta taaataaaca ggtactctat cggacaaatg aatttttcca
     2581 tcaaacagat acttatactc cgattcgatt gccacaacat tttattgggc aagaagaata
     2641 tgagcagcta atcatggtat ttgaaaatgt ctcatcagaa actgagcttt cttatatgaa
     2701 aaaaacagta aatgaatcca atgaagtaga tacatcttgg aacttcaaga tacagccaaa
     2761 gcttgaaatg acattgtatt atcaagggga tgtcaaatct tctcacgaga aggtacccta
     2821 ttctaatacc tcctttcgcg taacgtccat tgaagaatcg atcaaaataa aagattttga
     2881 aggtgaattt ttcttgatga cgagagaaaa agaagcctat gaacggttca tttcactatt
     2941 cactgatcga ttcaatcaag catttcacac tgattatgcc actaatattt ttgaagactt
     3001 tgaaaatagc tattcgtatt cggttatttc aaatacagac gtatataatt atcgagtgta
     3061 tttaactatt ggattgattc ttttattcct tttgttatca tcctttttct tattgatgaa
     3121 taaagaaatc agtttattgt tgaataatga cttttcatta catcaagtat tgtggtgttt
     3181 attggggaaa aagaaaatca ttattacatt cataattgca ggaatcattg gtggttttat
     3241 ttttatgtat tataaggagc aatttcttta tttgttccag atgtacgttt tcttgttcag
     3301 cggaatatat ggtatctctt tgatttctct tttattagtt gaaaaaatcg cttcgttaag
     3361 agaagcgttc aactatatcc aatacattct ttttacattt ggattgttgt tttctcttct
     3421 tttgaccgtt gccaatgtcg aattagcaac tatcgttttt tcttcttcac agttagctgt
     3481 ttcccatgaa ccaccaaaag aaatcgctgg tgaggactat catgtatttt atccagtaac
     3541 catcgggaaa aaccacgtgg attttattta ttccaatcgt tttgcatcag cagcagatca
     3601 ggaattatat gaaactttga ataaaaacgg aagtatatta gtcaatgtat cagattactt
     3661 gaatgaagaa aatgaacagt ttggcagagg gataaaaata aatctgaatt atcttaagaa
     3721 atttcctttg attgatgtct ctggaaggtt gatccaaata accgaaaaag aaacgcaccc
     3781 tgttatattg atccctgaac gatatagaca tacagattta aaaaatgacc tggcgcaaat
     3841 aacagaatat tatcaagaaa tcagtgaaaa agaaccgaaa tttctattta taaaaaacaa
     3901 tcaacccatt tatacattta ttccttctat cccctggatc gaacattatc cggttgttga
     3961 aatactgaca ttgaaaaaca gtatgtattt ggaaagaaat attctcagcg gagaaatcta
     4021 tccaccgtta aagatcaaga taggctcttt gtcgaaagaa aggttatttg agctgattga
     4081 agaaagtcag ttacgtgata acttgcagtt atcatttccg tatactcaga ctgaagagat
     4141 agctgtcaaa gtgttaagca gatcatttca ttacttgata cagatatttt tactcacttt
     4201 cttttctttc ttcttgttga gctatgtcat gttatgcata tattttgtct acaattgtcg
     4261 gaaaatcgct atctttcgtt caagtggtta ttcgctcttt gaaacgtata aagatttctt
     4321 catgatgaac ctcatcaaat ggggaacgac aagtgtaatc ttcctttttc ttatagaaag
     4381 agagcctaaa tatcttttta atattttttt ctttagcttc attgatttta ttctttcagt
     4441 tgtttttatt ttgtctacag aaaagaaaag tcagttattg ctgatgaatg gaggttaaca
     4501 attggagccg ttgatagtga taaaaggtgc gaaaaaaatc attcgaaaca aaacgattct
     4561 tcatttggat cgtttcactg cggatgctgg ggatcttgtg actgttgttg gagaaagtgg
     4621 agcaggtaaa agtacgttat tgaatatatt aggattgaat gatcagttca gttcaggaca
     4681 attctatttg ttcgatcaag agacgaaaca attaactggg agagagaagc gcttgataaa
     4741 aagaaatacc atatcttttc tttttcaaga ttttgggttg attgaatatg aaacaatcga
     4801 ttttaattta gatattggat tgaagttttc gaatttaaat gtttcagata agcgaacagc
     4861 aaagtatgag gcattgaaaa aagtaaatat aaacaagaag ctaagtacgc ctatctacac
     4921 attatctggt ggtgagaagc aaagaatcgc ctgtgcgaga gtcttattga agaatagcaa
     4981 aatcatttta gccgatgaac cgactgggtc attggataaa agaaataagg ataaagtagt
     5041 tgaaatctta tcgcaacaag cttcccaagg tacgttagtt atcgtagtca cgcatgatcc
     5101 atatctgacc aaaataggaa acaagaagat catgctttaa aaatcaaaaa ggaaaggatg
     5161 tcgttttatg aaaaaagcag ttattatttg tgcactaggg ataggttttg ttggaggaaa
     5221 cgctatgtca tctgaagtgg aagcaaattc agttcacggt gaaatctatt acaaatcttt
     5281 aaagccagga gagattcatt ttgatgctaa aggtaatatt attaagtcaa atttaccagt
     5341 agaccgggaa atttctagaa cagcaattaa tcatagctct ggaagatggg tttattatag
     5401 tgatacaact tgtacgagaa aaacaggtca ttctaaccac tatagtcgtg tctataatcg
     5461 tcacggtgca aaagcgaaag ttggaaactc tattcgatca gcaaatgcaa caaaaggagt
     5521 atgggcctat gcaagtgcga caggaaatag aactgacaca ttctcatgtt ggtacaatcc
     5581 aaccggttgg tattaagtat ccaaaagttt atataaaata gaaaaaacat ataatgaaac
     5641 agcgttaaaa gttatttttg gtagttttaa tatattcatt tttagttgta taaaaatata
     5701 tc
//
LOCUS       DAFEKH010000106         5683 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.110, whole genome shotgun sequence.
ACCESSION   DAFEKH010000106
VERSION     DAFEKH010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5683
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.110"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            133..1287
                     /locus_tag="LP386_002818"
     CDS             133..1287
                     /locus_tag="LP386_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBL1919991.1"
                     /translation="MEYSEERQRLAYVRLYGGILHLRDSVRISEKEKIKITEMYTSIN
                     GELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQ
                     REMLLDALLEISDSDPLLQYYVDSTTHEIILSFLGKVQMEVISALLQEKYHVEIELKE
                     PTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSF
                     QNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKA
                     GTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIVDTQLKNNEVILSGEIPARCIQEY
                     RSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRPNSRIDKVRYMFNKIT"
     gene            1385..2758
                     /gene="tet(L)"
                     /locus_tag="LP386_002819"
     CDS             1385..2758
                     /gene="tet(L)"
                     /locus_tag="LP386_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HBL1919992.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
     gene            3322..4584
                     /locus_tag="LP386_002820"
     CDS             3322..4584
                     /locus_tag="LP386_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HBL1919993.1"
                     /translation="MSYAVCRMQKVKSAGLKGMQFHNQRERKSRTNDDIDHERTRENY
                     DLKNDKNIDYNERVKEIIESQKTGTRKTRKDAVLVNELLVTSDRDFFEQLDPGEQKRF
                     FEESYKLFSERYGKQNIAYATVHNDEQTPHMHLGVVPMRDGKLQGKNVFNRQELLWLQ
                     DKFPEHMKKQGFELKRGERGSDRKHIETAKFKKQTLEKEIDFLEKNLAVKKDEWTAYS
                     DKVKSDLEVPAKRHMKSVEVPTGEKSMFGLGKEIMKTEKKPTKNVVISERDYKNLVTA
                     ARDNDRLKQHVRNLMSTDMAREYKKLSKEHGQVKEKYSGLVERFNENVNDYNELLEEN
                     KSLKSKISDLKRDVSLIYESTKEFLKERTDGLKAFKNVFKGFVDKVKDKTAQFQEKHD
                     LEPKKNEFELTHNREVKKERSRDQGMSL"
     gene            4829..>5683
                     /locus_tag="LP386_002821"
     CDS             4829..>5683
                     /locus_tag="LP386_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HBL1919994.1"
                     /translation="MCPNSSIYSDEKSRVLVDKTKSGKVRPWREKKIANVDYFELLHI
                     LEFKKAERVKDCAEILEYKQNRETGERKLYRVWFCKSRLCPMCNWRRAMKHGIQSQKV
                     VAEVIKQKPTVRWLFLTLTVKNVYDGEELNKSLSDMAQRFRRMMQYKKINKNLVGFMR
                     ATEVTINNKDNSYNQHMHVLVCVEPTYFKNTENYVNQKQWIQFWKKAMKLDYDPNVKV
                     QMIRPKNKYKSDIQSAIDETAKYPVKDTDFMTDDEEKNLKRLSDLEEGLHRKRLISYG
                     GLLKEIHKK"
BASE COUNT         1956 a          805 c         1167 g         1755 t
ORIGIN      
        1 tccttgtacc ctgtttatca tggaagcgca aaaagcaaca tagggattga gcagcttata
       61 gaagtgataa cgaataaatt ttattcatca acatacagaa agaagtctga actttgcgga
      121 aatgtcttca aaattgaata ttcggaagaa agacaacgtc ttgcatatgt acgcctttat
      181 ggcggaatcc tgcatttgcg ggattcggtt agaatatcgg aaaaggaaaa aataaaaatt
      241 acagaaatgt atacttcaat aaatggtgaa ttatgtaaaa ttgataaggc ttattccggg
      301 gaaattgtta ttttgcaaaa tgagtttttg aagctaaata gtgttcttgg agatacaaag
      361 ctattgccac agagagagag aattgaaaat ccgctccctc tgctgcaaac aactgttgaa
      421 ccgagcaaac ctcaacaaag ggaaatgtta cttgatgcac ttttagaaat ctccgacagt
      481 gacccgcttc tacaatatta tgtggattct acgacacatg aaattatact ttctttctta
      541 gggaaagtac aaatggaagt gattagtgca ctgttgcaag aaaagtatca tgtggagata
      601 gaactaaaag agcctacagt catttatatg gagagaccgt taaaaaatgc agaatatacc
      661 attcacatcg aagtgccgcc aaatcctttc tgggcttcca ttggtttatc tgtatcaccg
      721 cttccgttgg gaagtggaat gcagtatgag agctcggttt ctcttggata cttaaatcaa
      781 tcatttcaaa atgcagttat ggaagggata cgctatggtt gcgaacaagg attatatggt
      841 tggaatgtga cggattgtaa aatctgtttt aagtatggct tatactatag ccctgttagt
      901 accccagcag attttcggat gcttgctcct attgtattgg aacaagtctt aaaaaaagct
      961 ggaacagaat tgttagagcc atatcttagt tttaaaattt atgcgccaca ggaatatctt
     1021 tcacgagcat acaacgatgc tcctaaatat tgtgcgaaca tcgtagacac tcaattgaaa
     1081 aataatgagg tcattcttag tggagaaatc cctgctcggt gtattcaaga atatcgtagt
     1141 gatttaactt tctttacaaa tggacgtagt gtttgtttaa cagagttaaa agggtaccat
     1201 gttactaccg gtgaacctgt ttgccagccc cgtcgtccaa atagtcggat agataaagta
     1261 cgatatatgt tcaataaaat aacttagtgt attttatgtt gttatataaa tatggtttct
     1321 tgttaaataa gatgaaatat tttttaataa agatttgaat taaagtgtaa aggaggaatt
     1381 aattatgaag tgtaatgaat gtaacagggt taaatacaac caaattttaa tttggctttg
     1441 cgttttatct ttttttagcg tattaaatga aatggttttg aacgtctcat tacctgatat
     1501 tgcaaatgat tttaataaac cacctgcgag tacaaactgg gtgaacacag cctttatgtt
     1561 aaccttttcc attggaacag ctgtatatgg aaagctatct gatcaattag gcatcaaaag
     1621 gttactccta tttggaatta taataaattg tttcgggtcg gtaattgggt ttgttggcca
     1681 ttctttcttt tccttactta ttatggctcg ttttattcaa ggggctggtg cagctgcatt
     1741 tccagcactc gtaatggttg tagttgcgcg ctatattcca aaggaaaata ggggtaaagc
     1801 atttggtctt attggatcga tagtagccat gggagaagga gtcggtccag cgattggtgg
     1861 aatgatagcc cattatattc attggtccta tcttctactc attcctatga taacaattat
     1921 cactgttccg tttcttatga aattattaaa gaaagaagta aggataaaag gtcattttga
     1981 tatcaaagga attatactaa tgtctgtagg cattgtattt tttatgttgt ttacaacatc
     2041 atatagcatt tcttttctta tcgttagcgt gctgtcattc ctgatatttg taaaacatat
     2101 caggaaagta acagatcctt ttgttgatcc cggattaggg aaaaatatac cttttatgat
     2161 tggagttctt tgtgggggaa ttatatttgg aacagtagca gggtttgtct ctatggttcc
     2221 ttatatgatg aaagatgttc accagctaag tactgccgaa atcggaagtg taattatttt
     2281 ccctggaaca atgagtgtca ttattttcgg ctacattggt gggatacttg ttgatagaag
     2341 aggtccttta tacgtgttaa acatcggagt tacatttctt tctgttagct ttttaactgc
     2401 ttcctttctt ttagaaacaa catcatggtt catgacaatt ataatcgtat ttgttttagg
     2461 tgggctttcg ttcaccaaaa cagttatatc aacaattgtt tcaagtagct tgaaacagca
     2521 ggaagctggt gctggaatga gtttgcttaa ctttaccagc tttttatcag agggaacagg
     2581 tattgcaatt gtaggtggtt tattatccat acccttactt gatcaaaggt tgttacctat
     2641 ggaagttgat cagtcaactt atctgtatag taatttgtta ttactttttt caggaatcat
     2701 tgtcattagt tggctggtta ccttgaatgt atataaacat tctcaaaggg atttctaaat
     2761 cgttaaggga tcaactttgg gagagagttc aaaattgatc ctttttttat aacaggaatt
     2821 caaatctttt tgttccatta aagggcgcga ttgctgaata aaagatacga gagacctctc
     2881 ttgtatcttt tttattttga gtggttttgt ccgttacact agaaaaccga aagacaataa
     2941 aaattttatt cttgctgagt ctggctttcg gtaagctaga caaaacggac aaaataaaaa
     3001 ttggcaaggg tttaaaggtg gagatttttt gagtgatctt ctcaaaaaat actacctgtc
     3061 ccttgctgat ttttaaacga gcacgagagc aaaacccccc tttgctgagg tggcagaggg
     3121 caggtttttt tgtttctttt ttctcgtaaa aaaaagaaag gtcttaaagg ttttatggtt
     3181 ttggtcggca ctgccgacag cctcgcagag cacacacttt atgaatataa agtatagtgt
     3241 gttatacttt acttggaagt ggttgccgga aagagcgaaa atgcctcaca tttgtgccac
     3301 ctaaaaagga gcgatttaca tatgagttat gcagtttgta gaatgcaaaa agtgaaatca
     3361 gctggactaa aaggcatgca atttcataat caaagagagc gaaaaagtag aacgaatgat
     3421 gatattgacc atgagcgaac acgtgaaaat tatgatttga aaaatgataa aaatattgat
     3481 tacaacgaac gtgtcaaaga aattattgaa tcacaaaaaa caggtacaag aaaaacgagg
     3541 aaagatgctg ttcttgtaaa tgagttgcta gtaacatctg accgagattt ttttgagcaa
     3601 ctggatccag gagaacaaaa acgatttttt gaggaaagtt ataaattatt ttccgaacga
     3661 tatggcaagc aaaatattgc ttatgcaaca gttcataatg atgagcaaac ccctcacatg
     3721 catttaggtg ttgtgcctat gcgtgatgga aaactgcaag gaaaaaatgt gtttaatcgt
     3781 caagaactgt tatggctaca agataaattc cccgagcata tgaaaaaaca gggttttgag
     3841 ttgaagcgtg gtgaacgtgg ctctgaccgt aaacatattg agacagctaa atttaaaaaa
     3901 caaactttgg aaaaagagat tgattttcta gaaaaaaatt tagcagttaa aaaagatgaa
     3961 tggactgctt atagcgataa agttaaatca gatttagaag taccagcgaa acgacacatg
     4021 aaaagtgttg aagtgccaac gggtgaaaag tccatgtttg gtttgggaaa agaaataatg
     4081 aaaacagaaa agaaaccaac caaaaatgtt gttatatcgg agcgtgatta taaaaactta
     4141 gtgactgctg cgagagataa cgataggtta aaacagcatg ttagaaatct catgagtact
     4201 gatatggcga gagaatataa aaaattaagt aaagaacatg ggcaagttaa agaaaaatat
     4261 agtggtcttg tagagcgatt taatgaaaat gtaaatgatt ataatgagtt gcttgaagaa
     4321 aacaagtctt taaagtctaa aataagcgat ttaaagcgtg atgtgagttt aatctatgaa
     4381 agcactaagg aattccttaa ggaacgtaca gacggcttaa aagcctttaa aaacgttttt
     4441 aaggggtttg tagacaaggt aaaggataaa acagcacaat tccaagaaaa acacgattta
     4501 gaacctaaaa agaacgaatt tgaactaact cataaccgag aggtaaaaaa agaacgaagt
     4561 cgagatcagg gaatgagttt ataaaataaa aaaagcacct gaaaaggtgt ctttttttga
     4621 tggttttgaa cttgttcttt cttatcttga tatatataga aataacgtca tttttatttt
     4681 agttgctgaa aggtgcgttg aagtgttggt atgtatgtgt tttaaagtat tgaaaaccct
     4741 taaaattggt tgcacagaaa aaccccatct gttaaagtta taagtgacca aacaaataac
     4801 taaatagatg ggggtttctt ttaatattat gtgtcctaat agtagcattt attcagatga
     4861 aaaatcaagg gttttagtgg acaagacaaa aagtggaaaa gtgagaccat ggagagaaaa
     4921 gaaaatcgct aatgttgatt actttgaact tctgcatatt cttgaattta aaaaggctga
     4981 aagagtaaaa gattgtgctg aaatattaga gtataaacaa aatcgtgaaa caggcgaaag
     5041 aaagttgtat cgagtgtggt tttgtaaatc caggctttgt ccaatgtgca actggaggag
     5101 agcaatgaaa catggcattc agtcacaaaa ggttgttgct gaagttatta aacaaaagcc
     5161 aacagttcgt tggttgtttc tcacattaac agttaaaaat gtttatgatg gcgaagaatt
     5221 aaataagagt ttgtcagata tggctcaaag atttcgccga atgatgcaat ataaaaaaat
     5281 taataaaaat cttgttggtt ttatgcgtgc aacggaagtg acaataaata ataaagataa
     5341 ttcttataat cagcacatgc atgtattggt atgtgtggaa ccaacttatt ttaagaatac
     5401 agaaaactac gtgaatcaaa aacaatggat tcaattttgg aaaaaggcaa tgaaattaga
     5461 ctatgatcca aatgtaaaag ttcaaatgat tcgaccgaaa aataaatata aatcggatat
     5521 acaatcggca attgacgaaa ctgcaaaata tcctgtaaag gatacggatt ttatgaccga
     5581 tgatgaagaa aagaatttga aacgtttgtc tgatttggag gaaggtttac accgtaaaag
     5641 gttaatctcc tatggtggtt tgttaaaaga aatacataaa aaa
//
LOCUS       DAFEKH010000107         5460 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.111, whole genome shotgun sequence.
ACCESSION   DAFEKH010000107
VERSION     DAFEKH010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.111"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..177
                     /locus_tag="LP386_002822"
     CDS             <1..177
                     /locus_tag="LP386_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1919995.1"
                     /translation="QSLVLLAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGV
                     KDVLLNLFNRIVGA"
     gene            190..690
                     /locus_tag="LP386_002823"
     CDS             190..690
                     /locus_tag="LP386_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBL1919996.1"
                     /translation="MEQIRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELKGTPIGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCNDMSDVAYYLIVEAGDLGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFELM"
     gene            787..2634
                     /locus_tag="LP386_002824"
     CDS             787..2634
                     /locus_tag="LP386_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBL1919997.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEGLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMISDKVSIYSQKQIYEISKNQTSILELLDGYNSDLISEYKN
                     EIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIEDLKKQVEKLSHKSYKDVYDEYSKE
                     TDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGIKVTDEIDEHRGELIKNLVTNRAKI
                     QTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRYQRGIKNLVKSYLKMN"
     gene            2637..3533
                     /locus_tag="LP386_002825"
     CDS             2637..3533
                     /locus_tag="LP386_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL1919998.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNFYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            3583..3972
                     /locus_tag="LP386_002826"
     CDS             3583..3972
                     /locus_tag="LP386_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL1919999.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            3959..>5460
                     /locus_tag="LP386_002827"
     CDS             3959..>5460
                     /locus_tag="LP386_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL1920000.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKFQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDIQTDALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKSLKKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RCYSKLEKLMESKLARRFKVRRVTPSDLTYLIEHIYGEKGIPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPNRCLIEEKPRCLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPLSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKG"
BASE COUNT         1864 a          789 c         1159 g         1648 t
ORIGIN      
        1 caatctttag tcttactagc gattgtggtc attggtttgt ttttaggatt taaacgcgag
       61 ttttccaaac tgattggctt cttggtgatt gctttgattg cggtaggtct ggtctttaat
      121 gcttctggtg tgaaggatgt cttactcaat ttgtttaacc gaattgtcgg tgcctgaggg
      181 ggaatcacaa tggaacagat acgtgtttat attgcgaacc ttggaaaata caatgaaggt
      241 gagttggtgg gggcatggtt taccccaccc gtcgattttg atgaagtgaa agaacggatt
      301 ggattaaatg acgaatatga agagtacgca attcatgatt atgaactgcc ttttgagatt
      361 gatgagtata caccaattga ggaaattaat cggttgtgtg gtttagcgga agagcttaaa
      421 ggaacgccaa ttggtgaggt cgcttcagag attcaacatg ccttcttcaa ttctttcgag
      481 gaaatggtag agcatgtgga tgatatcatc tattatcccg attgtaatga catgagtgat
      541 gtagcgtatt acttgattgt agaagctggt gatttaggcg aagtaccaga acacttgaag
      601 acgtatattg attttgatgc gtgtggtcga gacttggaga ttggcgggaa ttatttggtt
      661 acgagtcgag gggtttttga actaatgtaa atcatttgtt agaattgacc agaaatttct
      721 atcgtacttt tacttttcta tttgatatac tgaaatagaa aatatttgtt gataggggtg
      781 ttactaatgg ttggcaataa gtggtacaaa tgtgatcttc atattcattc aactgcgagt
      841 cagtgctttc aggataaaaa ggttactgct aaggaatggg tagaagaatg tttaaacaaa
      901 ggactcgatt gtgttgcatt aactgatcac aatacagggg aaaatattga tgaatataag
      961 aaagtggcta tcgaaaatgg cttagatttt tttcctggag tggaattaac gtgtggagaa
     1021 aatggaactc atttactagt cctatttgat aaaagtgcat gtacaaatga tatctctgat
     1081 ttcttaacca agatgggtat aaaaagagag gattgggcca gcgctgcagc ttgctcaatg
     1141 aaatcagttt tagaagttat tgattttgct gagcacgagg gcttgctcgt tattcctgca
     1201 catatagatg agtttaatgg aatttcttca gcaaaatttg gaaatctagg aaagatattt
     1261 gaatcagaaa atatatatgc agtacagacg gttcaaaaag aattttttga aaatcgctca
     1321 caaatgattc cctcatctaa gcgtgacact atctatgata gtgtgaatgc cagatatgat
     1381 ggtagagttg gaaaagatac tttggaatct tggtataaat cagttgttga ggcagaaaaa
     1441 aataatatga catttcttag cttttctgat aacccacact cgaaaggaaa ttcaaaacat
     1501 ggactttggg gaataggcac aagatattcc tatataaaaa tgaaggacga acctgacttg
     1561 ggatcacttc gcgatgcttt aatgctaggc gaaactcgag ttcattctga tttttctaat
     1621 ttctccatta atgaaaatga agttttattg gaaaaattaa gcttttctgg gaccactctt
     1681 agcacaaaag aagttgtagt cgaattcagc gataatttaa cttcaattat tggaggaaga
     1741 ggaacaggca aatcttgtat tacaagattc ttggtctatg tccttggaaa ggaagcagaa
     1801 cttgatcaat tttctgaaat acaaagtgat tatcagaact ttgcacaaat tgaacataat
     1861 ggctctggaa tatttttgaa ggatacaatt gtgaaactga atattttcta taaggggaca
     1921 aaatatcaaa taataagaac acaggataga cattctattt atgaatttac acaagagaat
     1981 ggtctggttg aaaaagaaac agaacggttg agaatgattt ccgataaggt gagtatatac
     2041 tctcaaaaac aaatttatga aatttcaaaa aatcaaacta gtatactaga attactagat
     2101 ggatataact ctgatttgat ttcagagtat aaaaatgaga ttgaaacatg tgtaaacgaa
     2161 ataagaaaat taaattggga tattgtttct gtgaaaaaag aaatacaaga taaggcgaag
     2221 gtagagcttg aaattgaaga tttaaaaaaa caagtagaaa agctatctca taagagttat
     2281 aaagatgttt atgatgagta ttcaaaagag acagatattt atagggaact gaaacgtgat
     2341 gtggaggcac ttaaggaaat tcccaaaaat ctaactgata gtgttgacaa aattgacttt
     2401 ggcaatggta taaaagttac agacgaaatt gatgaacacc gcggagaatt gattaagaat
     2461 ttagtgacca atcgggctaa gattcaaaca ataattaatg aaatgtcaga tgaaattgat
     2521 agttatagag cagagctgaa taaatcagat tggaaagtta actataatga ggtttcaaag
     2581 aggtatcaaa gaggtatcaa aaacttagtg aagagttatc tcaagatgaa ttaaaaatgt
     2641 tacaaaacct tgattcttta tatcaatctt tatcaaaaac tgaagagcga ttggaagaaa
     2701 ttattcaaca agaaataaag cttaaagatt accaagttga ggttgactca gcaatgtcaa
     2761 gaatgaataa atcatatcaa aatttctatt ctgagagaag tagttcctcg cgcgaaattt
     2821 tttctgatat tacaggaata gaggctacta ttcaaccaaa tagggatttc aataattatg
     2881 ttaaagagct cagagcttgt attaataagg aggacacttt tgacagtgag tttggatctc
     2941 ttattgataa gctgacaaaa aattccatta ctaatcaaga tatatataat gacatacttg
     3001 atataagagt tagtggggaa agtagtattt tttcagataa aaaattaatc aattctataa
     3061 gaaaattgaa tgatgcacaa gttcttgaat tacaaaccct taagccaaat gatttagtag
     3121 ttatccgact tgaactaaat ggaaaaaaag ttagtttatc gaatgctagt gctggtcaaa
     3181 agacatctgc aattctttct atgattttgg cgtatggaaa ttcaccactc atattggatc
     3241 agcctgaaga tgatttggat agtcaattaa ttaataactt aatcgtaaga agtatcatta
     3301 caaaaaagga aaacagacaa attttaattg taactcataa tgcaaatatc ccagttaatg
     3361 gtgattcaga atggttgatt agcatgggag attcaaaaga aatatcggct gatcagtgcg
     3421 ggtcggtaga tgaacccaat atcaagccaa gaatatgtac tgtgatggaa ggtggcgagg
     3481 atgcttttac aaatagagcg aaacgctatg gttttaaaca aattgtagaa taacactaga
     3541 gggtgagaca tattattatg tccgcccttt ttaggaggaa aaatgaaaaa aataaaaagc
     3601 tataccagta tctgggcagt tgaaaaagtc atttacgcaa tcaatgattt tcagttgcct
     3661 tttcctgtga cttttaacca aatggcttgg ttcgttttat ctttactgtt tgtcatcgta
     3721 tttgcccatg tgcctccact atctatgata gaggaggtct ttttaaaata cttaggcata
     3781 ccggtggctg tcacttggtt tatgtcgcaa aagacgtttg atggcaagaa accactggga
     3841 tttttacgat cctttatcag ctatcacttg cgatttaagg tgacttttgc aggaaagaaa
     3901 gtcaaagaac agaagaaacg atgggatgaa cccagtactc ttgtaaggag tgtgaactat
     3961 gtatccgatt aagtatattg aaaataatct cgtctttaac caagaaggcg agtgttttgc
     4021 ctactatgaa ttagtgcctt acaattactc ctttttgtca cccgaacaga aatttcaagt
     4081 gcatgataac tttcgccaac taattgcgca aaatcgtgaa ggcaagatcc atgcgttaca
     4141 aattgccaca gaaagtagta ttcgcgccac acaagaacga tcaaaaaaag aaattaccgg
     4201 tagactcaaa gaagtagcga aacaacgaat tgatatacag acagatgcat tagtatccat
     4261 gattggcgat agtcagattg attatcgctt ttttattggc tttaaactaa ttgcgacaga
     4321 tgaagaagtc aatctaaaga gtctcaagaa atctttcttt tctgggcttc aagaatttgt
     4381 ctatggagtg aatcatcatt tgatgggcga ttttgtttcc ttatccaatg aagaaattcg
     4441 ctgctattct aagcttgaaa aattaatgga aagcaaattg gctcgaagat ttaaagtcag
     4501 gcgagtcaca ccgagtgacc tgacgtattt gattgaacat atttatggcg aaaaagggat
     4561 accgtttgaa gaatacgaat ttcagctacc aaagaaaaag ctaaaatcag aaacactggt
     4621 gaaacgttat gacttattac gtccaaatcg ttgtttaatt gaagaaaaac caaggtgctt
     4681 acggatggaa catgagaatc atgagtcgta cgtagcgtat ttaacaatta atacaattgt
     4741 gggggagatg gaatttcctt cctcagaact tttctattac cagcaacaac aatttacatt
     4801 cccaatcgac acaagtatga atgtagagat tgtgacgaat aaaaaggctt tagctaccgt
     4861 tcgtaataag aaaaaagaac tgaaagattt agacaatcat gcttaccaat ctgacaatga
     4921 aacgaattcc aatgtcttag atgctttgga ttccgtggat gaattggaaa ccaccttgga
     4981 tcagtcaaaa gaatctatgt acaaactgag ttatgtggtt cgagtgagtg ccgaatcagt
     5041 ggatgaacta aagcgacgct gtgatgaagt gctcgatttt tatgatgata ccaatgtaaa
     5101 actagtccgg ccctttggcg atatgatggg gctacatgaa gaattcttac ccttaagtaa
     5161 acgatatatg aacgactata ttcagtatgt tacgtctgat tttttggcgg ggcttggttt
     5221 tggggctact cagatgctag gagaattaga agggatttac tttggctaca atgtggatac
     5281 aggtcgtaat gtttacctga aaccggcatt ggcttcacaa ggagtcaagg gttcagtaac
     5341 caatgcgctg gccgccgctt tcctgggttc tcttggtgga ggtaaatcct ttagtaacaa
     5401 tctcttagtc tactatgctg ttttgttcgg tggtcaagct gtgattgtcg atccaaaagg
//
LOCUS       DAFEKH010000108         5416 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.113, whole genome shotgun sequence.
ACCESSION   DAFEKH010000108
VERSION     DAFEKH010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5416
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.113"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(444..2594)
                     /locus_tag="LP386_002828"
                     /pseudo
     CDS             complement(444..2594)
                     /locus_tag="LP386_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
     gene            2740..3315
                     /locus_tag="LP386_002829"
     CDS             2740..3315
                     /locus_tag="LP386_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1920001.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            3529..4224
                     /gene="vanR"
                     /locus_tag="LP386_002830"
     CDS             3529..4224
                     /gene="vanR"
                     /locus_tag="LP386_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBL1920002.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            4202..5356
                     /locus_tag="LP386_002831"
     CDS             4202..5356
                     /locus_tag="LP386_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HBL1920003.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT         1686 a         1039 c         1038 g         1653 t
ORIGIN      
        1 acctaaaaat attcgtataa tgaacttgag ttacggaact aggtgaagta gtttccgtaa
       61 aggtcgagag tgcgtcaaca ctgctcgact atttttttac tcttttttct cattttcttt
      121 gattatagca ctcctctaga aaaaataaaa agacctcagg gaatttcatt ccccgaaccc
      181 cttgagcctc ctcctgccga aatagaatgg cgctgccagc atttatttcg ttcagctatc
      241 ggctacacaa tctaacacga ccgttccgct accagtcgcc ttacaggctc cattttcgct
      301 cctctaacgt gtttcaccga ttgtgccgat aactaaacga aataaacgct aaaaccgctc
      361 agaacgcaaa atatgccatt ttagagctat tgtagaaaat atagtttgaa atgcaatttt
      421 cttctttcag ctttttattt cccacttgta aatcggtaga tggtggctcc ttttccagtt
      481 ccataatgtg gatttgcatc tgcatgtagt gatgaaacac ctagctgcat tctcatacca
      541 tctgacgaag atgttgtacc gtcgccccaa tagaaaggca attgtaattt atgatgaaag
      601 tttactaata tggcttgggc tttattcatg gcatcttcat acatgcgcca ttgagataca
      661 ttggctagtt gcttatatgt aagtccgggt gtggcttcgg ccatcttgct caagccaata
      721 ttcattccca ttcctaaaag ggcagccatg ataatgattg tttcttcctt atctggtttt
      781 cgattattgg aagcatgagt gaattgctca tgaaatcctg ttatatgggc cacatccatg
      841 agtaaatcag ttaattttat tcttggtagc atctgataaa ggcttgcact aaattttttt
      901 gcttcttctg gaacatcttt ttctaagcgt gcaagtgata gctttccttt ttcaagagaa
      961 accccatcta acttattgga attggcagct aaccacttta acctttcatt aaagctgctg
     1021 gttctctccg ttatataatc ttcgaatgat aaactaactg ataatctcgt attccccttc
     1081 gattgattcc atgtatcttc cgaaaacaaa tattcctcaa aatccctata ttgtctgctg
     1141 ccaacaatgg aaacatctcc tgcccgaaca tgctcccgaa gttctgttaa aacagccatt
     1201 tcatagtaat gacgattaat tgttgtacca tcatcctcgt ataaatgtct tttccatcgt
     1261 tttgaaataa aatccacagg tgagtcatca ggcacttttc gctttccaga ttcgttcatt
     1321 cctcggataa tctcaacagc ttgtaaaagt ggctcatttg cctttgtaga atgaaattcc
     1381 aatactctta atagcgttgg cgtatatttt cttagtgaat aaaaccgttt ttgcagtaag
     1441 tctaaataat catagtcggc aggacgtgca agttcctgag cctcttctac tgaagagaca
     1501 aaggtattcc attcaataac cgattctaaa accttaaaaa cgtctaattt ttcctctctt
     1561 gctttaatta atgcttgtcc gatgttcgta aagtgtataa ctttctcatt tagcttttta
     1621 ccgttttgtt tctggatttc ctcttgagcc ttacgacctt ttgataacaa actaagtatt
     1681 tgcctatcat gaatttcaaa cgctttatcc gttagctcct gagtaagttg taataaatag
     1741 atggttaata tcgaataacg tttattttct tgaaagtcac ggaatgcata cggctcgtat
     1801 cttgagccta agcgagacag ctgcaacagg cggttacggt gcaaatgact aatttgcact
     1861 gtttctaaat ccattcctcg tatgtattcg agtcgttcta ttatttttag aaaagtttcg
     1921 ggtgaaggat gacccggtgg ctcttttaac caacccaata tcgttttatt ggattcggat
     1981 ggatgctgcg aggtaataat cccttcaagc ttttcttttt gctcatttgt tagagattta
     2041 ctaaccgtat taaatagctt cttttcagcc attgcccttg cttcccacac cattctttca
     2101 agtgtagtga tagcaggcag tataattttg ttttttctta gaaaatctat gcattcatgc
     2161 agtagatgaa tggcatcacc attttccaaa gctaattgat gaaggtactt aaatgtcatt
     2221 cgatattcac tcagggtaaa agttacaaag tcgtattcac ttcgaatttc tttcaaatga
     2281 tcccaaagtg tattttccct ttgaggataa tgatcaagcg aggatggact aacaccaatc
     2341 tgtttcgata tatattgtat gaccgaatct gggatgcttt tgatatgagt gtatggccaa
     2401 ccgggatacc gaagaacagc taattgaaca gcaaatccta aacggttttc ttccctcctt
     2461 cgcttattaa ctatttctaa atcccgtttg gaaaaagtga agtaggtccc cagtatccat
     2521 tcatcttcag ggatttgcat aaaagcctgt ctctgttccg gtgtaagcaa ttctctacct
     2581 ctcgcaattt tcattcagta tcattccatt tctgtatttt caatttatta gttcaattat
     2641 atatcaatag agtgtactct attgatacaa atgtagtaga ctgataaaat catagttaag
     2701 agcgtctcat aagacttgtc tcaaaaatga ggtgatattt tgcggaaaat cggttatatt
     2761 cgtgtcagtt cgactaacca gaatccttca agacaatttc agcagttgaa cgagatcgga
     2821 atggatatta tatatgaaga gaaagtttca ggagcaacaa aggatcgcga gcaacttcaa
     2881 aaagtgttag acgatttaca ggaagatgac atcatttatg ttacagactt aactcgaatc
     2941 actcgtagta cacaagatct atttgaatta atcgataaca tacgagataa aaaggcaagt
     3001 ttaaaatcac taaaagatac atggcttgat ttatcagaag ataatccata cagccaattc
     3061 ttaattactg taatggctgg tgttaaccaa ttagagcgag atcttattcg gatgagacaa
     3121 cgtgaaggga ttgaattggc taagaaagaa ggaaagttta aaggtcgatt aaagaagtat
     3181 cataaaaatc acgcaggaat gaattatgcg gtaaagctat ataaagaagg aaatatgact
     3241 gtaaatcaaa tttgtgaaat tactaatgta tctagggctt cattatacag gaaattatca
     3301 gaagtgaata attagccatt ctgtattccg ctaatgggca atatttttaa agaagaaaag
     3361 gaaactataa aatattaaca gcctcctagc gatgccgaaa agccctttga taaaaaaaga
     3421 atcatcatct taagaaattc ttagtcattt attatgtaaa tgcttataaa ttcggcccta
     3481 taatctgata aattattaag ggcaaactta tgtgaaaggg tgataactat gagcgataaa
     3541 atacttattg tggatgatga acatgaaatt gccgatttgg ttgaattata cttaaaaaac
     3601 gagaattata cggttttcaa atactatacc gccaaagaag cattggaatg tatagacaag
     3661 tctgagattg accttgccat attggacatc atgcttcccg gcacaagcgg ccttactatc
     3721 tgtcaaaaaa taagggacaa gcacacctat ccgattatca tgctgaccgg gaaagataca
     3781 gaggtagata aaattacagg gttaacaatc ggcgcggatg attatataac gaagcccttt
     3841 cgcccactgg agttaattgc tcgggtaaag gcccagttgc gccgatacaa aaaattcagt
     3901 ggagtaaagg agcagaacga aaatgttatc gtccactccg gccttgtcat taatgttaac
     3961 acccatgagt gttatctgaa cgagaagcag ttatccctta ctcccaccga gttttcaata
     4021 ctgcgaatcc tctgtgaaaa caaggggaat gtggttagct ccgagctgct atttcatgag
     4081 atatggggcg acgaatattt cagcaagagc aacaacacca tcaccgtgca tatccggcat
     4141 ttgcgcgaaa aaatgaacga caccattgat aatccgaaat atataaaaac ggtatggggg
     4201 gttggttata aaattgaaaa ataaaaaaaa cgactattcc aaactagaac gaaaacttta
     4261 catgtatatc gttgcaattg ttgtggtagc aattgtattc gtgttgtata ttcgttcaat
     4321 gatccgaggg aaacttgggg attggatctt aagtattttg gaaaacaaat atgacttaaa
     4381 tcacctggac gcgatgaaat tatatcaata ttccatacgg aacaatatag atatctttat
     4441 ttatgtggcg attgtcatta gtattcttat tctatgtcgc gtcatgcttt caaaattcgc
     4501 aaaatacttt gacgagataa ataccggcat tgatgtactt attcagaacg aagataaaca
     4561 aattgagctt tctgcggaaa tggatgttat ggaacaaaag ctcaacacat taaaacggac
     4621 tctggaaaag cgagagcagg atgcaaagct ggccgaacaa agaaaaaatg acgttgttat
     4681 gtacttggcg cacgatatta aaacgcccct tacatccatt atcggttatt tgagcctgct
     4741 tgacgaggct ccagacatgc cggtagatca aaaggcaaag tatgtgcata tcacgttgga
     4801 caaagcgtat cgactcgaac agctaatcga cgagtttttt gagattacac ggtataacct
     4861 acaaacgata acgctaacaa aaacgcacat agacctatac tatatgctgg tgcagatgac
     4921 cgatgaattt tatcctcagc tttccgcaca tggaaaacag gcggttattc acgcccccga
     4981 ggatctgacc gtgtccggcg accctgataa actcgcgaga gtctttaaca acattttgaa
     5041 aaacgccgct gcatacagtg aggataacag catcattgac attaccgcgg gcctctccgg
     5101 ggatgtggtg tcaatcgaat tcaagaacac tggaagcatc ccaaaagata agctagctgc
     5161 catatttgaa aagttctata ggctggacaa tgctcgttct tccgatacgg gtggcgcggg
     5221 acttggattg gcgattgcaa aagaaattat tgttcagcat ggagggcaga tttacgcgga
     5281 aagcaatgat aactatacga cgtttagggt agagcttcca gcgatgccag acttggttga
     5341 taaaaggagg tcctaagaga tgtatataat tttggctctt tgtcaaatga tgttggtaaa
     5401 gagaaatctt agaata
//
LOCUS       DAFEKH010000109         5341 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.114, whole genome shotgun sequence.
ACCESSION   DAFEKH010000109
VERSION     DAFEKH010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5341
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.114"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(62..280)
                     /locus_tag="LP386_002832"
                     /pseudo
     CDS             complement(62..280)
                     /locus_tag="LP386_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(546..740)
                     /locus_tag="LP386_002833"
     CDS             complement(546..740)
                     /locus_tag="LP386_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920004.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
     gene            complement(840..926)
                     /locus_tag="LP386_002834"
                     /pseudo
     CDS             complement(840..926)
                     /locus_tag="LP386_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            2092..3132
                     /locus_tag="LP386_002835"
     CDS             2092..3132
                     /locus_tag="LP386_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBL1920005.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESGISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYE
                     SSPSTITKDWLE"
     gene            3956..4288
                     /locus_tag="LP386_002836"
     CDS             3956..4288
                     /locus_tag="LP386_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HBL1920006.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            4907..5248
                     /locus_tag="LP386_002837"
     CDS             4907..5248
                     /locus_tag="LP386_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HBL1920007.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT         1943 a          728 c          900 g         1770 t
ORIGIN      
        1 taggtatttt tattatatat agatttaaca tatgtcggtc ggttgattga tatagctaaa
       61 gttataactc aaccgaagcc gattcatcta cacgaataaa gttgcgagtg ttctcggcta
      121 attcataaaa attgttatgt gttccatata gcaatactgg aataacttta ttttcttgaa
      181 tctcataagc aactctatac acggtgaccg catacttaaa tccattagac caattacctg
      241 ataaacctcc agttttttgc tcttacttaa atggatcaat ggcaatttca tcacaaacct
      301 atagaggatg agtgacttct gcctaattac gttaaaaaat attgaaagta actctatgta
      361 gcaaaaaata tctagaattt catttcctca aaactgatcg atattgtatc taaaaatata
      421 tactacctaa aataggtagt atatattaaa atatgtgctt ttgttagaaa aatcaataca
      481 taaattatca tatctgtata tgtcatttag gtatttcagt tatgttataa tagttttgct
      541 gtctgctacc ccggcctaat ctggcaaggg gaggaggaga tataatgaaa tacctttttg
      601 attttgtttt tgcaatcaag ccacttgcag atgtagtgtg cagttacctc tgcaaatggc
      661 ttgattgcaa aattgccaaa aaagacagta agcctacccg ttaattctat aatatagaaa
      721 cgtaaaaaaa accccatcag cctgcacgct gatggggttt ggtgatataa tgaaatacct
      781 ctttgttact cataattgta ccataattag tcacgaatgc aaccaataga aaaaactact
      841 tagaacggta gatcatcgct aataacaatg cattgtccac caaatggatt ttgtgaagca
      901 ttaaatacat tgttattaat tgtcgctgct tttaactagg cctctcccct tctattataa
      961 aagaagatat atatcatttc ttaattacct actaccttaa accaaaattt aagtactacc
     1021 taatttaagt attacttaaa caatctaaaa aatagttatc ccaattgtta tgcttttata
     1081 atacgattat ttgtaacaaa atgaatatta tataattaaa cactaccata tttaggtagt
     1141 gtttaattat tagcaaaaca aaaaatattt attctattct cttaacttca actaagttat
     1201 gctgcacacc tttatataaa tcatatgcaa ctcattagct agacaaacta caagcatgta
     1261 gttttatctg ttaattatgt actacctaaa taaagtagtt tataattagc aagtatatat
     1321 atttaaaaat ttaagattaa tttttttatg acttgtacaa atttatctga tattctctta
     1381 ttaagaacta cctaatttgg gtagttctta ttttttacat tttaagtagt atttaattgc
     1441 aatttggtag tattttttta ttatcttatt cttagaacgg tagtacttaa tataaatata
     1501 ggtagtatct aatttaagta ttaatggtag tatctaaatt aacaggtagt atgtaactac
     1561 tttaaagtaa tttttttcag attaacacag tagtatctta ttaaataagt taattttaat
     1621 ggtagtacat aattattata tatatctgac attggtagta cttattgtat tttttagtag
     1681 tatataatct attgttttct agcctaaagc cttgtcttat aagaataata taatatatac
     1741 tactgaaata aggtagtata tattactagt aatggtagta tgttttatat gcataaggta
     1801 gttcttaatt tattttttgt tttgacactg gtagtactta attatcttta attttaaaac
     1861 taaattttat tcatacgttt ttctggtagt atttaattat aaataatatt tatttaaagt
     1921 agttcttaat gactttaaag gtagtacata attcatttta tttctgattt taggtagtat
     1981 ttaattaaaa aacagtttta atgcgtttgc attttttatt tatctttgct attttcgaaa
     2041 agagtaggta attttacata aataaaacaa cgtgaaagta gaggatctac aatgactgat
     2101 tttaaatttt ttaaggcgga tagagtttac aacgaattat tttatcaatt tccaaaagtc
     2161 tttattgttt ctgacgaata caaaaaaatg aaagattcaa ctaagattgc ctatatgctt
     2221 ttaaaagcaa gattagagat cgcaatcagc aaacggcaaa tcgatgaaga aggtaatgtt
     2281 tattttactt atacgacaaa tgaactatgt agagtattaa actgccaaaa acaaaaagcg
     2341 atagcaatca aaaaagagtt ggaatccttt ggtttattat tacaaaagca gatgggattt
     2401 aacaaacagt tagggaaaaa taatcctaat agactatatc tagcagaatt aaaagtctca
     2461 gaaaatgata tctacttact cgaaaaattt gatagagaga atagggaaaa cgttgataaa
     2521 tcagagggta tgaaaatcat acccaccctc gacgaaaaat cagacgctga atcccttggg
     2581 gctcaagagg gtatgaaaat cataccgtgc caaaacgttg ataaatcaga gggtatgaaa
     2641 atcataccag aacttaataa taatatatta gacactaata gacacaatat agacactgaa
     2701 aaagaccgcc tacaagatca attgttgtta gacaattttg agacaattat gacaaacgac
     2761 agcattgcta cgtttgtccc tgaacgagta ttaaatttga taaaaacatt ttcttcaagt
     2821 tacagtgaag ctcaaaaaac cgtccagact attcataatg caaagaaaaa agctgaaata
     2881 gaaagtggta tttcgatagt ttttgaagaa ctcgatagtt attatgtcaa tgcagaacaa
     2941 gaattataca cgacactgtt aaaagcctat caaaaattaa aaaccgaaaa agtcgaaaat
     3001 atccagaacc tgatttttgt ctatgtaaaa aattggttta tcgaaaaacc aatagctgct
     3061 aaagtatcaa gtgaaaaacg tttgaattat gaaagctccc caagcactat tacgaaagac
     3121 tggttagagt gaaactttac tgacaaagtg attgttgctt catggagtaa cattaaaatt
     3181 aaaaattttt tattattcta attatattac gaatattaca aaataatagc tattttaata
     3241 gaatttataa gttaaaatat tatgataaaa atcacaaacg tagcctttta cgtcataagt
     3301 gttaaaagaa ataattaatt tcaaatatag aaaagggaac gtatgtttgc atactccttt
     3361 tttttgagtt ataataatac gcgaagagag ataatttcat tatttaaaca agctaaaaat
     3421 cttgatatta cttcttttca ggcaatacga atattattcg cttacatttt ttgtataaat
     3481 ttaattgtct gctatgcttg tgatgaattg attttcgttc tgcacttttg gatgataaat
     3541 ttggacaatt gaaaatacaa aaaaaagaaa ggcggtatga actcggaagg ctggtaacct
     3601 tcgtcagcgt tcatacacgg cattaagatt tggcccttaa tgcgttaacc tttcagtgtt
     3661 acggtattac ccgcaatgga tttagtataa cagatattca aaagtgatac cacttttttt
     3721 ggctgtgtta aggttaaaaa tacgtgatat tacgatgaat ctatgcctaa gcacaatgtt
     3781 ataaaaatgt ccgtgtggct ctttgccgta tgacgaacgc tgaaattaga gggaacgcat
     3841 gtttggatgc gttccctctt ttttgtttgt catgaacgaa aatcaattct ctatttttga
     3901 aaaataacaa gaaaaacttg ttaaaaatat ttaaagaaat tgggtggttt attttatgtc
     3961 atatacagga attttgagtc tcaaagatat ttgtcactac ggtaaacggt gtaccgctac
     4021 agagaaaatc acgaagaaac tatcaactgg ccaaagtaaa accgttgtgc agtgtaagaa
     4081 atatataatc cagaaagaca aagtctcaga ggaaatgatt tattacattg ggaaacaaaa
     4141 gcaaataatt ttaaaagatc ctatcccctt aaaagagcta tatccaacaa tcaaacatgt
     4201 ttatgaccaa aacggtgtac tgattggtcg aagaaaaaat ggagtcttgc gttgtaccgc
     4261 aaaagggatg gggcgtttga tcggctgaat tgatcattct cataacttgt attttatcgt
     4321 ttttcgcttg cttgaaaata ttgtcgagac ttctaaagga acttagagtc actagaaaaa
     4381 taaggagtag acttgatcta tcaacaattc ccttcgggga gtgacggggt aggttttaac
     4441 gattggtaac gtaaaaaatt ggtcaatcga gtaaatgcgc ttgtttggat agtggtgaaa
     4501 tgaatttgtg taaataataa gcgcagagta aacaagaggg aatttagaag ttagacaagt
     4561 tagaatagcg tctagattaa tcatgagcag ctactaaggg atctagactt tgacgcaaac
     4621 tcatggaata aggagtaggt cttctcgtaa tggggaggac gcacaagaaa ttgtgtcgtg
     4681 tgctgcagta catgtagata cttgcgagga cgttgattat tggatcaatc gagcatttac
     4741 cgctgtctac tagggtttct cgtttcggac gccataaacg agtcgaaatt ttttatgtat
     4801 ttttaagtaa acgaaaaacg ataaaatatg aacaagtcct gaataaagtg aaaaaattga
     4861 tataaaacat agagaaaatg aaatttacgt aatggaggaa tgacaaatga aaaattatga
     4921 tccgaatata cgattgggca cacatactat taaggtttct ttccaacgtt gggattacaa
     4981 aggatttgtg acgtttagaa gaggcggaaa ttgtaaagga ttagatgttt tagcattaga
     5041 cgaggatgat ttatacgatc aaacattgac tgataatcca attggattcg gcttgctacc
     5101 tgaagatgat gaaggtaatg aatggtttaa aatgacgctt atgaatgata atggagacga
     5161 attatctgtt gaagatactt ggtcatattt gagtgattat attgtcagct ttgaaatcat
     5221 tgaatttgta gcggataaag aagaataaaa actggaggaa taaattttac agataaaggc
     5281 ttagaaggag tcacgatgat taataaaaag gtagtattac cttaggcatt gagtaaggaa
     5341 t
//
LOCUS       DAFEKH010000110         5234 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.115, whole genome shotgun sequence.
ACCESSION   DAFEKH010000110
VERSION     DAFEKH010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5234)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5234)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5234
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.115"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            37..939
                     /locus_tag="LP386_002838"
     CDS             37..939
                     /locus_tag="LP386_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL1920008.1"
                     /translation="MNIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISS
                     RDSEKFPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLL
                     FSDGSVTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFI
                     HSDRSIFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYFVTQNADDLLDEKMK
                     NNIGLKFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQ
                     FHPIFEELLHAFDTRPPVRNEVEE"
     gene            936..2963
                     /locus_tag="LP386_002839"
     CDS             936..2963
                     /locus_tag="LP386_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920009.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            2960..3982
                     /locus_tag="LP386_002840"
     CDS             2960..3982
                     /locus_tag="LP386_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBL1920010.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDDETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDLIFFHSTYNAGTYVTHVAIYLEGNRFYHAGDPIGYGDLSSRYWQDHLIGA
                     RRVIHN"
     gene            3999..4928
                     /locus_tag="LP386_002841"
     CDS             3999..4928
                     /locus_tag="LP386_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL1920011.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
BASE COUNT         1723 a          935 c         1068 g         1508 t
ORIGIN      
        1 gaatggaaag aaaccttacc tgatattgcc catgaaatca atattgttaa tctcacgagt
       61 gagaacgaca ataaagggtt acttgaccct tatgtgattt taaaactccc gaaagattca
      121 gaaagccttg ccattgatat tctcacgttc ttaacaggta tttccagccg agatagcgag
      181 aagtttcctg tcctgcgtaa agctattcgg agtgtaactc aaagcaaaca acgagggttg
      241 ttattggtga ttgatgaatt gcgaaaagaa gatacgccca tcagcaatag tattgctgac
      301 catatcgaaa gctttgtcga ttatgatttt gcccatctgt tattcagtga tggcagtgtc
      361 acccaatcca ttagcttgga aaaacaactc aatattattc aagtggcaga tttggtctta
      421 cccgattcca atagctcttt tgaagaatac actaccatgg aattattaag tgtggcaatg
      481 ctgattgtca ttagtacctt tgctttagac tttatccact ctgaccgttc catttttaaa
      541 attgttgacc ttgatgaggc ttggagtttt ttacaagtgg cacaaggaaa agctctatct
      601 atgcgattgg ttcgagcagg acgtgccatg aatgcagggg tctatttcgt tactcaaaac
      661 gcggacgatt tactagatga aaagatgaag aataatattg gcttgaaatt tgcctttcgt
      721 tccactgacc tagtggaaat caaaaagacc ttagaatttt ttggtgtgga caaggaagat
      781 gaaaacaatc agaaacgctt acgtgaatta gaaaatggac aatgtttagt ttcagacatc
      841 tatggtcgtg taggggttat gcagtttcac ccgatttttg aagagttgct tcatgccttt
      901 gataccagac cgcctgtgcg aaatgaggtg gaagaatgac acaaaaacaa aagaaatttc
      961 ttcactatag ttggataacg ctcctttgtg tgggcgttat tttactttta ttaggcacgc
     1021 tgggcaatgc agtacaagcg acaggcttag ttgatgaaac cattgataca agcaatgaat
     1081 actccaagta tggtttgaat caatatcagc ttgattatta tgtggacaat agctggggct
     1141 ggcttccatg gaattggagt gatggcatag gacaatcggt gatgtatgga ttgtatgcca
     1201 ttactaattt tatttggaca atttctcttt atctatcgaa cgccacaggt tatttggtga
     1261 aagaagccta tgccttagat ttcattagtc aaacatccca agcaattggc gaaaacatgc
     1321 agacgattgc aggcattaca ccgaatggct tttccagttc agggttttat gtcggtttcc
     1381 tccttctttt tattctcatt gttggaatct atgttgccta tacaggattg gttaagcgag
     1441 aaacgacgaa agtgatacga gctgttttaa actttgtcgt ggtgtttatt ctatcggctt
     1501 cctttattgc gtatgcaccc gattatattg cgaaaatcaa tgatttttcc aaagatgtca
     1561 gtaccgccag tctgaatatt gggacaaaaa ttgttcttcc taacacggat agtcaaggga
     1621 aagacagtgt ggacatgata cgtgacagct tattctctgt tcaagtaaag caaccatggc
     1681 tattgcttca atatggctcc actgatgtag aagcgttagg ggaagaacgt gtggaaagtt
     1741 tattgtctac cagtccagat acaaacaatg gtgaagatag agaaaatgta gtgattgaag
     1801 aaattgaaga tcatgacaat acctatttaa ccctaccgaa gacgatttcc agattaggaa
     1861 cagtcttctt tttgtttgta ttcaatattg gtatctcgat ttttgttttc cttctaacag
     1921 gaatcatgat tttttcgcaa gtgctattta ttattttcgc tatgtttttg ccaatcagtt
     1981 tcctattaag tatgttgccg agttttgatg gcatgggcag gcatgccatt accaagttat
     2041 ttaatgtgat tatgacaagg gctggtatta ccttgattat taccgttgcc tttagtattt
     2101 ccactatgct ttattcgctg tcagcaagtt ctcccttttt catgattatg tttttacaaa
     2161 ttgtgacctt tgcagggatt tattttaaac tgggcgattt aatgagccta ttcactttac
     2221 aaagcaacga ctctcaaaac atgggcagac aagtgtttcg cagacctcgt caaatgatga
     2281 atcgacaaac cagaagattt caacgcagta tgagtaagat ttttcgtgga aaagcagggt
     2341 caacgaagca aaagacaatg acaacaaagc agaatcaaac caataaagct aaccatactc
     2401 gtcaaaatga acggactaca ccaaagaaag aaacagcact ttccaatgtg aaaaagcaac
     2461 aaggcggtat cgggcaacga ttaggtgaaa agacagccca tgtattggac acgaaaaatc
     2521 gtctagtcaa taaaagaaag caggcaaaac aacagataca ggcgacacca acccatgtca
     2581 aatatgccct tcatcaagga aaagagaatg tcactcataa tgtaacagac tttaaacaat
     2641 ctatggcaga taccaaagct caacgcaaac aacagcgtat gaaccagcag gagcaaaaac
     2701 gaaagaacat tgctcaaaag cgtttggagc tggataaagc aaaagaaaaa agacgaaaag
     2761 aaaacccatc atctcctgtt cagaataacc agcagcatgt tcgcaagcgt cagcaaaccg
     2821 tcacgcctgt tttgtcacaa aacactaaac gtgaaaatca tcagcgacca ttgaaaaaag
     2881 agcaaaaaca aaagacacca ccgaagcaat tcaatcagag gaagctaaat aaaagaacgg
     2941 ataagcgagg acaacaaaca tgaagctaaa aataacagtg atttgtagtg tggtcttctc
     3001 tctcttcttt tttctcttat tattcctagt cattttcttt gcagatgata cggacagtgg
     3061 cgaaaacaac aaggattctt ctattccaca aggcggtgtg accgtttcac cagaagtgtt
     3121 ggcacaccgt ccgttgattg aaaaatatgg taaggaatat gggattgaag actatgtttc
     3181 ttatatctta gccattatgc aagtggaatc gggcggtaca gcagaagatg ttatgcaaag
     3241 ttccgaatct ttgggtttac cgcccaacag tttgagtacc gaagagtcca tcaaacaagg
     3301 ggttaaatat ttcagtgaat tattaaccag tgcagaacaa caaggagtgg atatagattc
     3361 tgttatccaa tcttataatt atggcggtgg ctttttaaat tatgtgagga gtcatgggaa
     3421 aaaatatacc tatgaattag ccgaacagtt ttctaaagag aagtcgggtg gtcaaaaagc
     3481 agactatccc aatcctatag ccatacctgt gaatggtggt tggcgatata actatggaaa
     3541 tcagttttat gttcagttgg tttcacaata cctaaccgac acttccccaa cagaatttga
     3601 tgatgaaacc gtgcaagtca ttatggacga agccttgaaa tacgaagggt ttccctatgt
     3661 ctttggaggg gcgtcgccta ccacctcttt tgattgtagt ggcttaatac aatgggtgta
     3721 tgacaaagct ggcatttctc tccctcgtgt cgcccaagat cagtatgacg ctacgcaaga
     3781 aatctctatg gaagaagccc aagcaggcga ccttatcttc tttcattcaa cctataatgc
     3841 aggcacatat gtgactcatg tggcgatata tttagaggga aatcgctttt atcatgcagg
     3901 cgacccaatc ggttatggcg acttaagcag tcgttattgg caagaccatc tgattggggc
     3961 tagacgtgtt attcataact aagaaaggaa tgaatcaaat gattataaaa atcgagcgaa
     4021 aagaaaagaa ggagaaacca aagaaatcta aaaaaccgag caagcaaaga aaagttccga
     4081 tgattaaagt tggcacgcat aagaaattaa cctttgtttt atgggtttta ttgattggta
     4141 gtgtcggatt tggaatctat aaaaatttta ctgccattga cactcatact gtccgtgaaa
     4201 cagaaatcat taaacagcag attgtcgata ccaaccaagt agaaagtttt gtgaaatcct
     4261 ttgcgaaaga ctacttttcg tggcaacaat cccaagaagc cattgataaa cgaaatgaaa
     4321 aattgaccca ttatttgacg gaagaattgc aggtattaaa tgaagaaatg attcgtaagg
     4381 atattcctac tagttctagt gtgaacgata tacaggtgtg gcaggtttct caagtgaatg
     4441 agaacacctt tgaggtactg ttttctgttg aacaagttat taccgaagac aaagacaagg
     4501 aaactatatc gtctagcttt catgtggttg tccatataga tgaatcagat aatatggtta
     4561 ttatcaaaaa tccgacaatg agtaagaaac ctcaaaaatc ggactaccaa cccaaacagc
     4621 tagaaagtga ccatacagta gatacagaaa cgatggacga aatcactagc tttttagaaa
     4681 cgttcttcca gctctatcct accgccacag aaaaagaatt gacttactat gtaagtaatc
     4741 atgtgttacc tatgattaac aaggaatatg ttttcgagga attggtgaat cctatcttta
     4801 ccagaaaaga taaccaagta atcgtgaatg tcgctgtgaa atatttagat caagaaacaa
     4861 aggcaaccca aatctcgcaa tttgagttga tattagaaaa acaagataat tggaagattg
     4921 taaaataaca aatattggta catgattaca gatactttgt aatcatgtac tctttttgat
     4981 aaaaaattgg agattccttt acaaatatgc tcttacgtgc tattatttaa gtgactattt
     5041 aaaaggagtt aataaatatg cggcaaggta ttcttaaata aactgtcaat ttgatagcgg
     5101 gaacaaataa ttagatgtcc ttttttagga gggcttagtt ttttgtaccc agtttaagaa
     5161 tacctttatc atgtgattct aaagtatcca gagaatatct gtatgctttg tatacctatg
     5221 gttatgcata aaaa
//
LOCUS       DAFEKH010000111         5188 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.116, whole genome shotgun sequence.
ACCESSION   DAFEKH010000111
VERSION     DAFEKH010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5188
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.116"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..307)
                     /locus_tag="LP386_002842"
     CDS             complement(<1..307)
                     /locus_tag="LP386_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL1920012.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNF
                     LKCGGTALEYFEQYKENKRRCGRTEIIFPAEEKEYIEKRSTEGWTPDVIIGRAERTFS
                     "
     gene            950..1513
                     /locus_tag="LP386_002843"
     CDS             950..1513
                     /locus_tag="LP386_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1920013.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
     gene            complement(1792..2079)
                     /locus_tag="LP386_002844"
     CDS             complement(1792..2079)
                     /locus_tag="LP386_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBL1920014.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(2069..2398)
                     /locus_tag="LP386_002845"
     CDS             complement(2069..2398)
                     /locus_tag="LP386_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL1920015.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            2703..3032
                     /locus_tag="LP386_002846"
     CDS             2703..3032
                     /locus_tag="LP386_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1920016.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCVLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            complement(3319..3804)
                     /gene="vanZ"
                     /locus_tag="LP386_002847"
     CDS             complement(3319..3804)
                     /gene="vanZ"
                     /locus_tag="LP386_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HBL1920017.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(3957..4868)
                     /locus_tag="LP386_002848"
     CDS             complement(3957..4868)
                     /locus_tag="LP386_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HBL1920018.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
BASE COUNT         1667 a          901 c          801 g         1819 t
ORIGIN      
        1 aagagaaggt tcgctctgca cggccaataa tgacgtctgg ggtccaacct tcagttgatc
       61 ttttttcaat gtattctttt tcctcagcag gaaaaatgat ttcggttctc ccacaacgtc
      121 gcttattttc tttgtattgt tcaaagtatt caagtgctgt tccaccacat ttgagaaagt
      181 tatagacatt gtaaattgtt tggcgtccac gtttaagctg cttcgcaacg atagcaaccg
      241 gagtttcttg atgaaaatat gcttctatca ttacaagctc gtttggtgta agatgggtat
      301 aagtcattta tgttcactct ccttgtatgc tttagcgggt attacaattt gagtgtaaca
      361 taaatggctt ttttatttgt ctcgcttaat tatacaaacg gcgaagttaa aactttttta
      421 gcagatttta aagtttcgtc aaaactaata tattctggta gctgagcatt caaatagctt
      481 tcagacttca gaagaaaatt acgagcattt ttatagtcca tctctaataa agttattctt
      541 tttttatcca atacattcag ctcaattcct tataatattc tattccttag tatctcaaca
      601 ttatttactt tataaaacga ataaattttg tagttctaat tcaaatattg catgttatat
      661 ctaatatggg agcattttat aattttcatt gtgataaact cgttattaac tttaggatac
      721 actagttagg attaaattag gtatctagaa atttacttaa gatttttttg tttatttcgt
      781 atacacactc gtatcaaaaa caatcgatta tcagacaaaa tgaaatgacc tcttttatta
      841 aataaaagag gtcatatttt gtatcataac ttgttgcatt aactatgtat ctataactcc
      901 cttttatgat acaatcaagc cagaattaaa gtacgaaagg aagaaaagca tgagtggata
      961 catttatggt tatgcccgag tgagtacacg ttcacaagaa ctaaatcgtc aattagactt
     1021 actcaatgaa caaaattgta atgaaatcct aactgagaaa atgacgggaa ccaaagcggt
     1081 tcgtccccaa ctaaatcgtt taaaagataa aattcgtccg ggagatacgg taattgtaga
     1141 aagtttttct cgattgggtc gtagtacaaa ggatttgatt gaccttgtta cctattttga
     1201 agaacaccat gttaagctgg tgagcttgaa agaaaacttc gataccagca cgcctcacgg
     1261 acgcttaatg atgactgtct tccaagcatt tagtcagttc gaacgtgatt taattgttga
     1321 acgtaccaaa gaaggtttga aaagtgcacg tgcgagaggt cgtaaaggtg gccgtccacg
     1381 agtgaaccag aaagatgttg atcgagcagt aaaattgtat aaaagtcagg tttatagcgt
     1441 aaaagaaatt acggaaatga ctggtattag caaggcaaca ctctaccgct acttaaaaga
     1501 caatagggaa taatctattt taatctttag gaatctataa tatttatggg agaattagag
     1561 tgattttttt attattacta aaaaacaata taaaataacg cattttaagc cctctttgtg
     1621 cataaggatg aagcttttaa tttgaaagag gcttaaaatg cgttttaatt ttttctattt
     1681 ttcataaata tataggttag tggtttaaaa ttatagggta ttacaactct cagctgttaa
     1741 aaattatctt ttaaagtgtc gtctatcctc tcaagttgaa acattgggtt cttacctaat
     1801 cttttttaat tgttcataaa aattttcatg cgttccacat agtaagatag gtatcactgc
     1861 attatcttta atttcatatg caacgcgata tgtcgtacct gcatacttga atccaatagc
     1921 ccaaattcct gataaatcac ccgttttttg ttctcccgaa tgaggacgaa ctgctatctc
     1981 atcataaatt atcgttaaaa attgttcttt taatgttttc tcttttaatt tttttagata
     2041 ctttattacg tgtttagaag gtagaatctc ataagccaat ttctgctgcc aactcctctt
     2101 ttgtcatcgg tttagaattt gcaacagtat cttcagcaat agatttaaat gcagaagtta
     2161 acgcattttt tctatttcta aattctttta agatctcttg tttgctataa ccttctgaaa
     2221 gaatatcagc caaaatatct tcactaaaat caaaaaattc ttttttaggc tctacaaact
     2281 cataaaggat accattctct acaagcttag cttctacttc aacaccattg ggcacatcga
     2341 attctttagg gaccgttaac ataatagaat ttccttgttt tcttgttttt gtaatcatat
     2401 tatttcctcc attattttac atttcgtaat tacttagtaa ttacattgta cgctattttt
     2461 agtagaaata caaaataata aaactccttt agaacaattt tcaaaggagt tttatttgat
     2521 taggaaatta tgtagaataa taatatgttt ttaacttgga atcaaaaacg cacttgcaag
     2581 taagtttact tcaatacatg aaattgctta taatagtgta ttggaattaa ggtagattga
     2641 caaaagagtg atcaaatagg tatacttcat tcaaataatc gtttgaatgt gaggtgagat
     2701 gaatgaaaaa agtttgccaa gtgactgtcg tacataaaga aaaagtaaat ggaataaaaa
     2761 ataaattgga tcaaaaagat ttttcaaact tacttgtgtt agggaaatgt ttcagcgatt
     2821 tttctagaat taaaattttc tatgctttag aaacctataa ggaaatgtgc gtctgtgttt
     2881 tagcagaaat acttactgct agtgtcgcta caacgtcaca ccatttacgt tttttaaaaa
     2941 aacatggaat ggcaaaatca cgtcaagatg gaaaagtagt ttattactct ttagcgaatg
     3001 aagacatcct ttccgctatt cgtgtttttt aaagttatca gaaaatctat ctatgaaatc
     3061 ttagtttggg ggtaccgtca ggaaaatgcg gatttacaac gttaaggaaa tttattaaag
     3121 agaccaattc ctcagcacta aaattgataa ttgggctttc tttgttacta tagtgttagg
     3181 taagcttttt actttatcac cggttttccc ctcacttcac acctacgggc gagtttcccc
     3241 acatcccgtt ttccatctaa tccaattcat tcaatatctt tatgtgtatg aaagatcaga
     3301 ttgcttgatt tagacatctt acacgtaatt tattcttaaa tgggtacggt aaacgagcaa
     3361 taatacgagc aaaagtatac ctacaaaaat aataactctg tctaattttt tttgattcat
     3421 atgcttattg cttaaaccat ataatttcag tccaagaaag cctccaacag tatttgtaat
     3481 tacatctgtt atgtctgtcg ctccaatagc gaagataaat tgaattattt caaaagtaag
     3541 acttaaaacc agtacaaaag caaacttagg taaaaatccg atttctttaa aattgacatt
     3601 caaaagcaag ccaaatggaa taaagattat aacattatct atcatctctc tgaaattccc
     3661 agtagcagta aatggagtca agttaagact tctttgatga taattaaata ctgataaaat
     3721 attgtattgt aatttgaata acactaacca gattagtgtc actaaatata aagctagcaa
     3781 tcctctagat aatatttttc ccaatataat ttcctctaat tcttttgttt aagttgtatc
     3841 attagtatag caatgtccta gttaacgtgg gttttaaatt aaaaagctaa cgttacccca
     3901 aaagtgctag tacaataatg ctgttcatta atttcgttgg tttcattccg ccatccttac
     3961 ctccttgaat tagtatgtgt tgatccggga aacactgtca caattacacc gtctatattg
     4021 tttcctgata tctcataacg aagattagtc ggcacatgaa tggtggtatt tttagtaaca
     4081 ggataataaa agatctcata tttttcccca tttacactaa cagaaatggt tttttcttct
     4141 tttaggtaat ccatatattc ctcgagaacg aaattctttt ctttcataat cgcactatgt
     4201 ggtaaaccaa catagcgaat atgccatggt tcatattgaa ttcctgttaa ctctgttttg
     4261 tcctctggat aacgtaaaat gaacccgtat ttccaagcat tttcttctat ccactttcct
     4321 tcaggggctc gttccatttt cgtcaagctt gatcctacat ctagtgataa acctgaatta
     4381 tgctcactat aacctgctgg taaggcatac tcagccccca tttcttggta aagcacactt
     4441 tgctcatcaa agtctcgata gccactatta ataataaaat gactaacgcc accctttaca
     4501 gcatcattga ccatctctga aaatttttgt gctatttctt ttgacatata aatattacta
     4561 tcaagcaacc cgtatccatt tattaattcg tcatgtttag ataaattcac gatatctgac
     4621 ttcacacttt cttggcgaac aggatattta ctattgatta atagcagatt tccttgataa
     4681 acctgttctt ctgtaattgt tttctcttgg gtattttcag aagtcccact attttctaaa
     4741 tgttctttgg gattttgatc ataattttga aattcgactt tttcctgaga aaacagtgct
     4801 tcattaacgt agtcataacc taagtatatt aagaataaca ataacaataa aaaaaacaac
     4861 ttcttcattt tcagtctcct ccttaactat atagttggaa gtatgaaata tttctagaat
     4921 cttcccctta aacggcacaa tctcgtttga gattgtgccg ttttgccccg taaattacag
     4981 tcaattattt cgccctactg gatttactat tatcaccaat gtagatgaat tttcataagt
     5041 gatacccatg ctgaatttaa cgaggctgaa ctgcctgttg acaatgggcg gtgtgaaata
     5101 ccacccctct atgcgatcag tcttattatc aggctatctt gccgcagcgc acgcagataa
     5161 tgaccgcaat atcgctctgc cttacatc
//
LOCUS       DAFEKH010000112         4921 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.117, whole genome shotgun sequence.
ACCESSION   DAFEKH010000112
VERSION     DAFEKH010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4921)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4921)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4921
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.117"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..297)
                     /locus_tag="LP386_002849"
     CDS             complement(<1..297)
                     /locus_tag="LP386_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1920019.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKER"
     gene            483..1418
                     /locus_tag="LP386_002850"
     CDS             483..1418
                     /locus_tag="LP386_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL1920020.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
     gene            complement(1503..2513)
                     /gene="gap"
                     /locus_tag="LP386_002851"
     CDS             complement(1503..2513)
                     /gene="gap"
                     /locus_tag="LP386_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBL1920021.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            2807..4114
                     /gene="obgE"
                     /locus_tag="LP386_002852"
     CDS             2807..4114
                     /gene="obgE"
                     /locus_tag="LP386_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HBL1920022.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            4335..>4921
                     /locus_tag="LP386_002853"
     CDS             4335..>4921
                     /locus_tag="LP386_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HBL1920023.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
BASE COUNT         1547 a          858 c         1097 g         1419 t
ORIGIN      
        1 cctttctttt cgcccgataa tgacgtcagg cgtccaacca agagtgactt tctctttaat
       61 gtaatctact tcatgagcag gtaattgaat gacttttcta ccacattttt tcttattttc
      121 tttatactgg tgccaataat caagagcagt cttgccttgc ttgaacttat tgactacatt
      181 ataaatagtt tgtatagcac gtcccattcg gttagcgatt tcaaccggct tattatgttg
      241 aagataatat gattctatca ttgtcagttc gtctatggta agatgtttgt aggtcattta
      301 tggttacact cctttgtttt ctttcgtcgg aaatacaatt tgagtgtacc ataaatgcct
      361 ttttattttt ctaacttaat tttacaattc gcgggttata aaaatgaaca ttgcatagta
      421 gagattcttt gattatacta attcaaggtt atatgaaaaa agagaaatga gatggatgat
      481 ttatgaaact ttggatgaaa atccttttag gcgtcgcttt agctctgatt gttgcgttag
      541 tgtttgcagg gaattatttt tataattatg ctgttgtgcc ttctgagaaa gactttttag
      601 acgaagatac acctggtaca acacagacat ccaaagaaac ggatgcacat aaatggttta
      661 gttcaaaaga aaaccgaagc gattggacca tcacttcaaa agacggtctg aaattatcag
      721 cgatttatct tcctgctgaa acgaaaagtg aaaaaacagc tcttgtggct catggctata
      781 tgggaaacgc tgaaacgatg accaattacg caaagatgtt tcatgatatg ggttacaatg
      841 tccttgttcc tgatgcaaga ggacatggaa aaagcgaagg ggattacatt ggatttggat
      901 ggccagagcg taaagactat gtacagtgga taaacaaagt gctagaaaac aatggaaaat
      961 cgcaagaaat cgttctatac ggtgtcagca tgggagcagc aacagttatg atgactagcg
     1021 gagaaaaact accagataat gtgaaagcaa tcattgaaga ttgcggttat tcttccgttc
     1081 atgatgagct tgcttatcag ctagacgata tgtttagtct tccagcattt ccgcttatgc
     1141 aagtaacgag tctagtgaca aaagtccgtg ctggctactt tttcggtgaa gcaaatgcag
     1201 tggaacaatt gaagaaaaac cagcgcccaa tgctctttat acatggagac gaagatacat
     1261 ttgtaccatt tgaaatgtta gataaggtct atcgtgcaac gaagggacca aaagaaaagt
     1321 atgttgtaaa aggagccgag catgcggaag catacaagac agatcctgaa aaatatcagc
     1381 aagtagtcca acaattttta agccaatatg ttcattgaac gagtttaaaa gtaggggatg
     1441 aaaagaaaga agcctttgac tggatccagt caaaggcttc ttttatcgat tgatctatca
     1501 aattacaagt tagcgaattt ttctagtaag cgaatcattt ggcaagtaaa tccatactca
     1561 ttgtcatacc atgcaacagt tttaacaagt tggaaatcac cagcagttgt tacttctgtt
     1621 tgcgttgggt caaagatcga accttgagtt gttccaatga catcgctaga aacgatttga
     1681 cggtcatcat acccgaatga aggattgtca actgtgtgtt ttttgattgc ttcgtttact
     1741 tgatcagcag ttacttttgt tttcaatact gaaaccaatt cagttaatga accatcaacg
     1801 actggaacac gttgtgcgtg tccttgtaat tttccttgta gctcagggat aactaagccg
     1861 attgctttcg cagcaccagt agaatgtggg atagtattgt cagcagctga acgagcagca
     1921 cgcaaattac cgccttttac aggtccatct aagagcattt gtgtggaagt gtaggcatga
     1981 actgttgtca ttgtaccaac ttcgatccca aattcattat ttaagaaata agccataggt
     2041 gctaaacagt ttgttgtaca tgaacctgct gagatgattt tgtcgttttc atctaatgta
     2101 tcatcattga cgttatagac gatggttttc atagcaccag ctggggcaga aataactact
     2161 cgtttgacac cagcatctaa atgcgctttt gctttttctt cagatgtata aaaaccagta
     2221 cattctagta cgatatctac accgttttct tttgcccaag ggattttgct tgcgtcgggt
     2281 tctgcataaa cacgagttgc ttcgccatcc actacgattg agtcttctgt tgcagtaact
     2341 gtgccaggat aagtaccatg agtagagtca aattgcaata attgtgctaa catagttgga
     2401 cttgttaagt cgttgattgc tactacttca atatcatctg agacttcttt gatgcggcgg
     2461 aaagccagac ggccaatacg cccaaatccg ttaataccta cttttactgt catatcaaaa
     2521 gttcctcctt tattaggggt gctgtgaaac ggcatcctca attaatacaa ttaatacact
     2581 gttattctgc tacgcaaaga atattttgtc aaaaaattat acttggtagc agaaaaaagg
     2641 ttggaaacct taccaaatga taaaaaaaga agaaggtaaa caatcttttt gctgaaatga
     2701 tagacaaaat cagatttcac cgataaaata agtaagactt ttgtttattg tggaaattca
     2761 ggcagtcaaa taaataaatg aataatagga ggacttaatt atgtccatgt ttttagatca
     2821 agtaacgatc gatgtgaaag ctggcaaggg cggagacgga atggttgcat ttcgtcgcga
     2881 aaaatacgtt cctgacggcg gaccggctgg cggagacggt ggtcgtggcg gcgatgtcat
     2941 cttgatcgtc gatgaagggt tacgtacatt gatggatttt cggttcaatc gccatttcaa
     3001 agcgcagcca ggtgaaaatg ggatgagtaa agggatgcac ggtcgtggtt cagaagatac
     3061 ctatgttaaa gtaccacaag gaaccactgt ccgagatgcg gagactggtg ctcttttagg
     3121 agatttaatt gaaaatggtc aaacactagt tgtggcaaaa ggtggacgcg gtggacgagg
     3181 gaatatccgt tttgcctctc ctcggaatcc tgcaccggaa attgctgaaa acggtgaacc
     3241 aggacaagag cgaaaaatcg aactagaatt gaaagtattg gcagacgttg gacttgtagg
     3301 ttttccatct gtcgggaaat cgactttact atccgttatt tcatctgctc gtccaaaaat
     3361 cggcgcttat catttcacga cgctcgtacc taatctagga atggttacta caagtgatgg
     3421 cagaagtttt gccgcagcag acttgccagg cttgattgaa ggagcttcgc aaggtgttgg
     3481 gctgggtaca caattccttc gtcatatcga aagaacacga gtaattttac atgtgatcga
     3541 tatgagtggg atggaaggac gagatcctta tgaagactat cttgccatca acaaagaatt
     3601 atctacttat aacttacgct tgctagagcg tccgcaaatc atcgtggcaa acaaaatgga
     3661 tatgccggat gcaccggaaa atctagtgaa attcaaagaa cagctgaaca aggaaaaaga
     3721 agatgaattt gctgatgaca tcccagtatt tccaatttct ggagtgactc gacaaggatt
     3781 ggacgcgtta ttgaatgcta cagcagattt gttagaagta acgccagaat tcccattgta
     3841 cgaagaagaa ctggaagaag aaactgtaca ctatggattc aatccagaag gtcctgagtt
     3901 ccaaatcgat cgtgattcag atgcaacgtg gatcttatct ggtgagaaga tcgaaaaatt
     3961 attccaaatg acgaatttcg atcatgatga aacagtgatg cgttttgctc gtcaattacg
     4021 tggtatgggt gtggatgaag ctcttcgggc acgcggtgcg aaagatggcg accttgtacg
     4081 tatcggtgag tttgaatttg aatttgtcga ataggcaagc aaataaaaac aaataccaaa
     4141 aaatatagat tcagatttaa gggaggttgt gacagaagtg atcagcttca agaacgccgt
     4201 ttattcggaa aaaggagctg tgatacgact tttgtcacag ccctatttta ttggaaaaaa
     4261 agagtgcttt tcttttctta tttttcaatt aaaggtaaaa taaataacaa gaaggtatga
     4321 aaggggcgtt tttaatgagc aaacgagtaa tcattttaaa ttttcaagta gaaagccagg
     4381 catatcaggc attttcagaa atcaaaaagt tacatgctgt tcgttcgatt aaaggagaac
     4441 agatggcagt tgtcagccat gatcctaatg ggacacatca attcaaaata gaagatttta
     4501 tcgactttac cggtaataac aaatcttcta cgggtggatt aatcggaatg ttggttggtg
     4561 tattaggtgg tccgctaggg attttattag gatggtttgc cggaggaatg atcggtgcga
     4621 cacaagatgc caaagaaata aaagatgccc agaccgtgtt cgactttgta ggaaataaaa
     4681 tcggtgaagg agctacagga ctgatcttga ttgctgatga agaggacaat cgcccactga
     4741 atcaattggt aatgatggaa ttaggcggag aaattactcg cttggattat gaagatgtcg
     4801 aaaaagatgt gcatgatgcg aaagaagctg aaaatcatgc gaaagaagct gcacaaaaga
     4861 cttggaagga caaacatccg caaacttcca acgacaatga aagttctgga tcttcaaatt
     4921 a
//
LOCUS       DAFEKH010000113         4807 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.119, whole genome shotgun sequence.
ACCESSION   DAFEKH010000113
VERSION     DAFEKH010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4807
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.119"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(89..1174)
                     /gene="xerS"
                     /locus_tag="LP386_002854"
     CDS             complement(89..1174)
                     /gene="xerS"
                     /locus_tag="LP386_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HBL1920024.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
     gene            complement(3250..3768)
                     /locus_tag="LP386_002855"
     CDS             complement(3250..3768)
                     /locus_tag="LP386_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HBL1920025.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
BASE COUNT         1579 a          786 c          730 g         1712 t
ORIGIN      
        1 taaaaatgat aatgaagctt gcctttaaag ttgggctttt atctaatttt agagacaggc
       61 ttcattatta tactattttt tactacattt acaaagcgtt caaagcatca attgtagctg
      121 cattgtctat atgagtatat aaagttgttg tatttgtact tgtatgtccc aattgttggg
      181 cagttaatac caatgaattt gtctgttgat agagtctagt agccaaagta tgacgtaatt
      241 tatgtggact gacttggact ctgaatcctt ttgaatattt tgctaccatc cgttcgattg
      301 caataccgga tatacgcttg gcttctcctt gataaattgc tagaaataaa gctttttcgt
      361 tttctgttac tttgtatcgt tctttccgaa tagctagata attagctaaa tattccattg
      421 caaatgctgc tatatttact gcgtctctct tatttccttt tctagttact accacattat
      481 tcttttctaa agataggtcc tctaaattaa tatttacaac ctcggagagt cttaatccag
      541 atcctaaaat caatgcattg atcgccaggt ctctttctac atctcgttga taatagatca
      601 aagctcgttt gctcaaagtt tttttatatt cattggcaat ataatctaga taattttgtg
      661 tatcttcgtc tagaaataat tttttctcga ttgcgtttgc acgggcagct aacgtagttt
      721 tatctgtgat agttgctact tgatccatag gattattttc taagtatggt tttcctaaag
      781 gattattgga acttttcgaa agatatttaa atagaacctt taatgctgtg atatttctat
      841 tgatagtaga agtagataga cctaagttat tattatcttt gagcttagtt tttgttgtct
      901 ctttttttac attttccttt gtgcgacgtt tcaaatgaga tttgtacaag tttagatcat
      961 aggcagttaa ctgtcttatc gaggtgattg aagtatcggg aacgatagac tcactcagaa
     1021 gccattcata aaagagctta taatttttta gatattctaa agtagttcga ggtgattgat
     1081 ctttatcctc acgatcttga acaaaatctt ttatataatc gggcatatga agtatgattg
     1141 tatctatttt ttgatatatt tctgtatttt tcatgttatt catcctttcg ataagtaggg
     1201 gagaggagta tctctataat tggactatac caattataga gtgttttgtc aattggtata
     1261 ctctgaaatt tattaattta tttcaaaaaa gcagataaat aggtatagat ttaataattt
     1321 aaaataaatg gtatacatga ataggaaagg aaacagaagg aggcaatctt aattttttaa
     1381 attgtctaaa ttatatagaa agaacaatct ttctatataa ttagacataa gagagactac
     1441 ggttgatttg atattaacaa gcgtatatga atgtatatac aaataaaaaa ggggagggag
     1501 aagttaaaga aaattcagag aagtggggca ctcagtagta ttaacaattt aaaaggaatt
     1561 tcttaaagaa aatgggttgc atcctggaga tacaattttt ttagataaag aaaaaattca
     1621 agcaacaatt caaaaaaatc ttaactgctg agattgatgt agcaatatct caatcatcaa
     1681 caaagtacga tcctgccttt caaaagctta ttgataaatg tttattcatt ataaaaataa
     1741 aagaaaaatt tatgtcagct tttttcatca aagtggtaat gataattcgt ctattaattg
     1801 tattttttag gaaatatggt ataattgttt taacgaaaag gtaattcatg atacaccaaa
     1861 aaccactagc tggcgggcta gtggttttct tttacgttct attcagatta acgggtaggc
     1921 ttactgtctt ttttggcaat aattttgcaa tcaagccatt tacagatgta atgcgcggat
     1981 acttctgcta agattgcaaa aaacatatcg aaaaggtaat tcataataca acctcctccc
     2041 cttgccataa taggccgggg tagcagacag cataaatatt ataccataac tgaaaatttc
     2101 attttagtac atttcaatat attgatgaac cagcacaata aaacatgcca tgactaacag
     2161 aaaaaaactt attaaaccag atataacttg taaacatcca actatataga aaacgtaaat
     2221 tttctatata gttggattaa gataacgact atttatttta tcatattttt actataccct
     2281 atacttttac ttggtatatt tatgaataat cgcaaattta cccctatact actagtttgt
     2341 aagttagatt aataaaaata ctaaagttat ttgttctttt attaaataca cctacaactt
     2401 ataaattgat ggtatttaga taacacgaaa gaataaaaat aacagctgat agtaaagttt
     2461 gttgacgatt gctactcaat cgaaagtgag ttagtgcgta tgaacttgct tctgaaaact
     2521 tatgaaatga aagacctttt acatcttgca gaaatcggta ctgggattaa actaagcaat
     2581 aaaaactaat gttcccctca ttctttgaac ttctactatt tgatttattt attctgataa
     2641 atgacgattt caccttcagg atcttcaaat cccgtataga atttatttaa gatctcttca
     2701 gtatcagtaa taggataggc gataggccac ataccctttg atggttagaa taaactgctc
     2761 aaaatctgta tcgtatgttg gctttagcat attaacaaag gctatctcca aattataaac
     2821 cataagcgtt gaatcgttct taacaatttc aattcttcct aacccaaagt cagaagatat
     2881 aattaccgga cttgccttac ccttcatgtg ggttgttgag attccatatt taaagggaat
     2941 tgtcggtact atcggcggtc tgaaaaacat cccaaaaata aaaaaatctt tcccctgcta
     3001 gtctcctaag tccctttgta gcggatatgg caccataatc tcattttatc gaagtgagtc
     3061 atggtttatc tgttggccaa ccaaaattga tacaatctaa cgatgcaccc tctacggcat
     3121 tctaggggag tgcacttgca ttcacccaat aaaaaccggc agttagcaaa gaacttatgt
     3181 agtcgtatgt tcttactgtt aacatacaag aggtctcctt tccacaattg cttagcagta
     3241 aacgggaatt tacaaagcta atctcttcca ttttcttatc tttgttctaa aagtcccaaa
     3301 tggagcaact gtatttacat gaataaattt atatacttcc catacagccg ttttggttgc
     3361 ctcgtctgcc cattttcttt tgtgtgcagt gaatagatct tcatcactca ttgaatcaat
     3421 catcatgtta atatcatcaa tattacgatt gagaatttcc tctaattctt tcaatggtag
     3481 atgtgcatag gtatttgtaa accacttata taactctcct aactgattcc atttaaattg
     3541 atcagaaggc gttttaacag ataatccatt tctttcatca ttttcccatt ttagaattaa
     3601 attcgtccaa ccaacttgat atgctaaatt ttcagcaggt gttctatcca cttcctcaac
     3661 tcttttatcc ttcaattctt caggaatagt ttcaaattct aaaatatatt tagtataagt
     3721 cctatttatt tcttttttta attcttcttt atttttatat gttctcatta tattacctcc
     3781 ataaattcct aattgtctcc tttaattcat ctataatttc atccacgata ttttaatccg
     3841 ttctacaatg catatctgat atgcattgac tgtctaactc atatgtgaat gatttataaa
     3901 atatcccaac gtctcatcta aagaaatgtt gatcgtcagc aaggagctaa aaaatacgaa
     3961 tatatttctt ttgtagtaaa atcggactgg tttgcatatc attttcttcg taaatatcaa
     4021 aatcatgtta actactatca attactaata aaaactacca ctttaagcgt taagaactgt
     4081 taagtttagt taagtgagga tagttcacaa aatccattgt taaacttcac gaaagtggta
     4141 aaactcaaaa tgctttatat aggattacag catcgctctt tcttcgattg cgcgttgggt
     4201 aaaaaatatt atgaagtaaa aattgacgat gacacgttcc ttacggctca tcagatgaaa
     4261 cagctacaaa aacgaaatga tcaactcgaa gaaaatttaa ttctaaaaaa gcgattgcca
     4321 tattcacgcc tcgctcgacg aactattaaa ggtcaagatt tacctgaaga tcatcctttt
     4381 taggaaattg aagcttttta tgttgcacaa tgcatttata atactacaat gatgttttca
     4441 ccagatattc ttctagggtg cggtgtaatg aaacagatac acttgcaaaa gaaaattcac
     4501 cgcgaattta ctaaaattat gaataattat gttaatcttc cgaaattttt ttccaaaatt
     4561 aagggatcaa gctggtgtta tagattgttt aaggttggca aaaaaataac ttctttttaa
     4621 acaattatag aaaaccgata ctctgttaag ttggttgaca cggtgtcgat ttttatgact
     4681 ttcttattct gaaacttcac taacggacag tacctaaaaa gtctatagta tggacgttta
     4741 cgagtactat tttatcaaaa atgctgctca tttcaactta tatgttttag tgaactaccc
     4801 ccactta
//
LOCUS       DAFEKH010000114         4772 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.120, whole genome shotgun sequence.
ACCESSION   DAFEKH010000114
VERSION     DAFEKH010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4772
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.120"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..196)
                     /locus_tag="LP386_002856"
     rRNA            complement(<1..196)
                     /locus_tag="LP386_002856"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            complement(882..2387)
                     /locus_tag="LP386_002857"
     CDS             complement(882..2387)
                     /locus_tag="LP386_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL1920026.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2384..3070)
                     /locus_tag="LP386_002858"
     CDS             complement(2384..3070)
                     /locus_tag="LP386_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1920027.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(3263..4684)
                     /gene="gndA"
                     /locus_tag="LP386_002859"
     CDS             complement(3263..4684)
                     /gene="gndA"
                     /locus_tag="LP386_002859"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HBL1920028.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1317 a          996 c          800 g         1659 t
ORIGIN      
        1 gattgttata cggtattagc acctgtttcc aagtgttatc cccttctgat gggcaggtta
       61 cccacgtgtt actcacccgt tcgccactcc tctttttccg gtggagcaag ctccggtgga
      121 aaaagaagcg ttcgacttgc atgtattagg cacgccgcca gcgttcgtcc tgagccagga
      181 tcaaactctc ataaaaagtt cgaacaatct tgcgattgtt aagctcaatt tgtttgctag
      241 catattgctt gcttgttaaa aatgtttgtt gtcttgaatt gaatcaagac gccctacaca
      301 tttggtttgt cttactttgt tcagttttca aaggtctaat ctttttgttt taacaactct
      361 ttaatcttat cagattcaga agagaatgtc aacaacttct ttgtttattt tttctaaacg
      421 tctttgccac tcattagcag cgacttgatt atcataccat ctttattgtt atttgtcaat
      481 aactttttcg aagttttttt cgataaaatc aagctttatt agctatctca tccaaacgac
      541 ttcgttatta taacatgaca tcaaaagtgc gtcaacacta ttttttataa tttttagtga
      601 caccttaaag gaatcattta gaacaaataa taatatagca atctctttat aaaattgcaa
      661 tagaaaattc cctattttta tttattattt ttaaacacga atattacagc attttattgt
      721 tttttcgttc atctaaaaga tacttacatt taattaacgg atgttattct atttaattgt
      781 tcgctagttt ttttataatg acatccctga atttctcact tgcttgtatt ttgtacctta
      841 ttctttgttg gatatataaa aaaacaagta aagcacatgc tttacttgtc ttctgccttt
      901 gcgataggaa taaagattct aaaaattgtc ccttgcccta ctacactttc tgctaagata
      961 cgtcctttat agttttcaac cagttgttta gcgatagaca accccagacc atttccaccc
     1021 ttcgttctag ctcttgcttt atccactcga taaaaacgat tgaagatctt attaaggtct
     1081 tctttgggta ttccttcgcc aaagtcctga atcgcgatct caaattcatt cagagtggaa
     1141 gaaatagaga tatggacttc ttttcgtgta gttgaatact ttactgcgtt atccaatatg
     1201 ataatgatta attgttcaaa gtgattacga taaatttgca gggtcacttc ttttgtcaaa
     1261 tcatcatcta aagtgatcac atagtctgga tataatatct tgaaattatt ataaacttga
     1321 taggtgactt cttttccttt agttgtttca ttcgcataat gaacatctac ttgttctgct
     1381 cttgataagt ctagcatctc ttgaactaag cttttcatac ggctgatttc ttgcatgctg
     1441 gcgcttaatg attcttctaa tatctcagga tcatctttcc cccaacgatt tagcagacta
     1501 agatgccctt caataattgc aacaggtgtc cttaactcat gagatacgtc ttccacgaat
     1561 tgctcttgtt gttcaatata caaacgcata cggtcaagca tctcattgaa tatttcagct
     1621 aaatctgcca attcatcatt tgtgtcgatt tcaggcatgt ggatatctga ttgcggatct
     1681 ttacgtatag tatccattgt atctctgagt accttgagtg gttttaagaa ataagaagat
     1741 aaaaagaaac ctaaaatact acttaagatc aaagaaacaa cttctaaaac aataagagtc
     1801 aataatagct tatttcgaat atcatagaaa gaagataatt catagaagct ttgcgcatag
     1861 ccgatctttt ctcttgtacc tttagaatat ataggctgga tagataaaaa gccagttttt
     1921 ccttctagtg taacgatcgt tggaacttta cgtgtagtct gaatcaggtt tcgactgttt
     1981 tcatgggttt taaaaatcaa gttctcgtcc aaatcataaa cataaagatc cattgatggc
     2041 tgccctagct cagctataaa ggaatcgatc ttcattaagt ttccttcgac cagtgaagta
     2101 tgatctacga cctcatctcc gtcatttgtc gctttcgtca gattacgata cgtatttact
     2161 aatgtcagtt cttcatccga gttagccaaa cgagaagcta cttctgaaat cgtacgctct
     2221 acattgtttc tttcttttgc cacaatcaga ttgatagatg atttataggt aatgacagcg
     2281 aaaattgtaa acacaacgaa tatgaagaaa gaactcgcaa aggcccactt gattgtcaag
     2341 gagggccctt tcagttctct tttttccgat tttttcggct ttatcacgag cgcatcacat
     2401 aacctgttcc gcgtacagtt tggatatagc tttcctcccc gggaacgtca attttgttgc
     2461 gaagataacg aatatatacg tccactacgt ttgtttcaac ttctgtttcg tatccccaca
     2521 ctttatttag taaaacgtca cgtgctaata ccacgttcac gttttccatt aaagtaagca
     2581 gcaactcgta ttctcttttt gttagttcaa ttacttcatt tccgcgacgt acgacacggt
     2641 tttctttttc gatagtcaaa tcgcgataag taatagtagt ttgtttagcc acatttttat
     2701 cgccttcaat atcgattcga cgcaacaatg cacgaagacg tgctaataat tcttcgatag
     2761 caaatggttt gacgatgtag tcatctgctc cgtggtcaag tccagataca cgatcgatca
     2821 cagaatctct tgcagtcatc ataatgattg gtgtattttt gacttggcgt acacgtctgc
     2881 agacttctaa accgttcaat tctgggagca tcagatccaa caatatggca tcccactcat
     2941 tatttaatgc cgcatctaaa ccagttcggc cgttgtagtg gacttctgcg ttataccctt
     3001 catgcttcaa ctctagctcg acaaatcgtg ccaagttctt ttcatcttca atgattagaa
     3061 tattgctcat ttattatttt atcctttcta ttctactggc tttttaaaaa ctctatcatt
     3121 ataccgataa tatgcttaaa aatctatagt cattttatca tggatagcaa ttttaaaaaa
     3181 gagctgaagt ctactcataa caatcgactt cagctctttc gtcctctttt tattttctca
     3241 tttcctaaca gccgaaagac tattattctt catggtacca tgagtaatgg aagattcctt
     3301 ctttgtcgac acgctcatag gtatgtgcgc caaagtaatc gcgttgggct tggattatat
     3361 ttgcaggcag acgttctgct ctgtatgaat cgaagtaagc gatggctgat gagaaagtcg
     3421 gtacaggtac gccagcttgg acagccaagg caacgacgtc tctgactgat tgctgatatt
     3481 ttttcgtgat ttcaacgaag taatcatcta gcaataaatt ttcgatctca ggatttttgt
     3541 cataggcatc cgtaattttt tgcaagaatc gagctcggat gatacatcca gcgcgccaga
     3601 tttttgcgat ttcaccaaat ggcaagtccc aatcaaattc ttttgaagcg acacgtaatt
     3661 gagcaaatcc ttgggcataa ctcatgattt tactgaaata caacgcttct cggatttttt
     3721 cgaccaattc ttttttgtct cccgtgaact caaaatcgtt cgtacgagac aaaatcttgc
     3781 ttgcttgtac gcgttcttct ttataagcag aaatatagcg ggcaaataca gattcagtga
     3841 tcaatggaag tggcacacct aagtcaagcg cgctttggct tgtccattta cctgttcctt
     3901 tattcccagc tgcatcaagg atcacatcta ctactggttt acctgttcct tcatcgtctt
     3961 tacgtgtcag aatgtcagca gtgatttcta tcaaatagct gtctaattcg ccttgattcc
     4021 attctttaaa gatatcagcc atttcttcta ctgaaaggtt taaaatattc ttcattaagt
     4081 cataagattc agcaatcagt tgcatatctc catactcaat accgttgtgt accattttca
     4141 cataatgtcc ggctccattt gggccaatat atgtgacaca tggtgctccg tcttctgctt
     4201 ttgcagaaat ttgctctaag attggtgcaa ctagcgcata ggcttctttt tgtccaccag
     4261 gcatgattga aggtcctttt aaagctcctt cttcaccacc ggaaacgcct gtaccgataa
     4321 agttgatgcc agagttggct aactcttcat tacgacgcat cgtatcttta aagaatgtat
     4381 ttcctccgtc aatcaaaata tcgcctttat caaggtgagg aagtaactct tggattgttg
     4441 catctgttgc cggtcctgct ttgaccatta gcaagatccg acgtggtttc tcgatagatt
     4501 ctacaaattc ttcgattgta tatgttgctt tgaaattttt atctgggtgt tcttctacta
     4561 cagcggttgt tttagcccct gtacgattga ataaagccac tgaatagccg cggctttcta
     4621 tgttcaaggc tagattttta cccataacgg ccataccgac aacgccgatt tgttgttttg
     4681 acatatgaac tcctcctaca tacgggattt ctccctaatc tcttacatta tagcttaaca
     4741 cggctacatt gcaaactaaa gaacaacata tt
//
LOCUS       DAFEKH010000115         4639 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.121, whole genome shotgun sequence.
ACCESSION   DAFEKH010000115
VERSION     DAFEKH010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4639
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.121"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..187)
                     /locus_tag="LP386_002860"
     CDS             complement(<1..187)
                     /locus_tag="LP386_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1920029.1"
                     /translation="MPRRQRRTYSKEFKQQIVDLYLAGKPRAEIIREYELTPSSFDKW
                     MKQAQSTGSFKERDNLTP"
     gene            257..418
                     /locus_tag="LP386_002861"
     CDS             257..418
                     /locus_tag="LP386_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002608889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBL1920030.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
     gene            437..1714
                     /locus_tag="LP386_002862"
     CDS             437..1714
                     /locus_tag="LP386_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1920031.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1724..2380
                     /locus_tag="LP386_002863"
     CDS             1724..2380
                     /locus_tag="LP386_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1920032.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2380..3756
                     /locus_tag="LP386_002864"
     CDS             2380..3756
                     /locus_tag="LP386_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1920033.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(4042..>4639)
                     /locus_tag="LP386_002865"
     CDS             complement(4042..>4639)
                     /locus_tag="LP386_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1920034.1"
                     /translation="YKSNPKECVNCPLLNQCTKSKNHQRVITRHVWGDLMDEVEHLRL
                     TDLNKSIYKKRKQTIERIFADAKEKHGMRWTKYRGLEKVATHTMLVFAAMNLKKLATW
                     LWKGKEPLFFCSKIRNEVDKKLFQARVTSLEQLLSTVCDVGDISFSIRNQLRFKRSLP
                     VSGNINVYFTKARFKRLIAITVSSIVMFLWLFRMGVIP"
BASE COUNT         1756 a          564 c          822 g         1497 t
ORIGIN      
        1 ctggtgttaa gttgtctctt tctttgaatg agcccgttga ttgtgcttgc ttcatccatt
       61 tatcgaaaga agaaggcgta agctcatact ctcgaataat ttctgcgcga ggcttaccag
      121 cgagatagag atcgacgatt tgttgtttga attcttttga ataggttctt cgttgacgtc
      181 ttggcatgaa aaatcctcca gtgtgttttt tattattcta cacaccttat tttttctgtc
      241 tagtctagtg tagccgattc aggataagga taagtgtatt aattgtggaa aatgtaaaaa
      301 agtttgccaa atgaataaag attcagttga gaattgcaat catctggagt gtatcagatg
      361 tggacgatgt aaaaatgctt gtccagtgga tgcaattagt tatggagtaa gaaaatagag
      421 aggagtagtt aggaaagtga taaaaaatgc tatagcatat attacaagaa agaaaaatag
      481 aactttaata atttttatca tattaactat agttctttct tgcttgtatt cttgtttaac
      541 aataatgaaa tcaagcaatg aaatagaaaa ggctttatat gaaagttcta attcttcaat
      601 atcaataaca aaaaaagatg gtaaatattt taatgttaat caatttaaag atattgaaaa
      661 attaaaagaa attgaagaaa aaataattca atatgatgga ttagcaaaat taaaagatgc
      721 taaagtagtt agcggagaac aaagaataaa tagagaagat ttatctgacg aatttaagaa
      781 tgttgtttca ctcgaagcta caaataatac taaaagaaat attttattta gtagtggagt
      841 atttacaatt aaagaaggta aaaatataga agaaaatgat aagaattcaa ttattgttca
      901 tgaagaattt gctaaacaaa acaatctaaa attaggtgat gaagttgatc ttgaattact
      961 agatattgaa aaaagtggaa aaataaaaag tcataaattt aaaattatag ggatcttttc
     1021 tggtaaaaaa caggaaacat atacaggatt atcttctgat tttagtgaaa atatggtgtt
     1081 tgtagattat tcaacaagcc aagagatatt aaataattca gaaaataatg aaattgcaaa
     1141 taaaatttta atgtattctg gtagtgcaga atctacagac ttagccttaa acaaattgaa
     1201 agagcttaaa attgatgagt caaagtattt tgttgaaaaa gattctaatg cgtttgaaga
     1261 gtctttagag tcagtgagtg gaataaaata tataataaaa gtaatgactt attctattat
     1321 gttaggtggg atggttgttc tttcattaat cttgattcta tggttaaggg aaagaattta
     1381 tgaaataggt atattcttat ctattggaac atctaagata caaattataa tgcaatttat
     1441 attcgagtta atattcatat cgataccaag tataatatct tccttatttt taggaaatgt
     1501 attactaaaa gtaattgtag atggattcat taactcagag gattcaatga tttccggtgg
     1561 aagtttaata aataatagta gttttatgtc aaatataaca acacttggac aaagttattt
     1621 aatattaata agtattattg ttttatcagt tgtatttgct tcttcattaa tgttaatcaa
     1681 gaagcctaaa gaaatcttat caaaaataag ttaggagaaa ataatggata tattagaaat
     1741 aaagaatgta gcatatagtt atgcaaattc taaagaaaaa gttttgtcag gagtaaatca
     1801 aaaatttgaa cttgggaagt tttatgcgat agtaggaaag tcaggaacag gaaaatctac
     1861 acttctttcc ttacttgctg gacttgataa acctcaaaca ggaaaaatat tgtttaagaa
     1921 tgaagatata caaaataaag gatatagtaa tcatagaaaa aataatatat ctttagtatt
     1981 tcaaaactat aatttaatag attatttatc accaattgaa aatattagat tagtaaataa
     2041 atcagcagat gaaagtatct tgtttgaact aggtttagat aaaaaacaaa taaaaagaaa
     2101 tgttatgaaa ttatctggtg gacagcaaca aagagtagct attgctagag cattggtatc
     2161 agatgctcca ataatactag ctgatgagcc tactggtaat ctagacagtg ttactgctgg
     2221 agaaataatt aatatattaa agacattagc taaagataga aataaatgtg taatagttgt
     2281 aacacatagt aaggaagtag cagattctgc ggatatcatt ttagaactaa gtggtaaaaa
     2341 gttgaaaaaa gtaaataaaa tgaatttgga ggttgaataa tgataaaaaa tgcatttgct
     2401 tatgtaacta gaaaaagttt aaaatcatta attatcatat tagttatttt atctatgtca
     2461 actttaagtc tcattagttt atctattaaa gatgctacgg acagagcttc aaaagaaaca
     2521 tttgctaata taacaaatag tttttctatg gagataaata gacaagtaaa tccaggaaca
     2581 cctagaggtg ggggaaatgt aaaaggtgaa gatattaaaa agatatctca aacagatagt
     2641 atagactcct atgtaaaaag aataaacagt gttgcagatt tagttgatta tgatattatt
     2701 gaaactcaag agactcttgc gaatcaatca cctgaaagag caaagaattt taaaagaaca
     2761 gttatgttaa ctggggttaa cgactcaaca aaagaaacaa aatttgtatc agaagcatat
     2821 aaattagtag aaggaaagca tttagaaaat gaagataaaa ataaaatctt aatgcataaa
     2881 gatttagctg aaaaaaataa ccttaaagtt ggagataaga taaaaataaa atctaattta
     2941 tttgatgctg ataatgagaa aggtgcagat gaaacagtag aagtagaaat taaaggtcta
     3001 ttcgatgggc ataatagcgg tgtagtaagt gcagcacaag aactatacga aaatacatta
     3061 atcactgata ttcatacagc tgctaaagtt tatggtaata ccgaagatac agctgtatac
     3121 caagatgcaa cattctttgt aaaaggtgat aagaatcttg atagtgtaat aaaagatctt
     3181 gggaaattag atataaattg gagagaatat aatttgatta aaagttcatc aaattaccct
     3241 gcattacaac aatctatatc aggtatttac tcaatttcaa ataaattatt ttttggctca
     3301 ttaatatttg caggagttgt agtttcatta ttattattct tatggatgaa tgctagaaag
     3361 aaagaaatag cagtattact atcattaggt atatcaaaat tagaaatttt tggtcaattc
     3421 ctaattgaga tggtatttat atcaatcccc gcattcgttg gttcctattt cttagctcaa
     3481 tatacagctg acaagcttgg gaataatata ttgaataagg ttactggtga tatagctaaa
     3541 caaatagcta aacaatctgc atctagccaa ttaggtggtg gggcagaagc tgaaggattt
     3601 aacaagacat tatcaagttt agatatcaat gtattaccta aattcatgat ttatgtagtt
     3661 atatttatga gtttagtact tcttgtatca ttgattattt cttcattcaa tatattaaga
     3721 aggaatccaa aagaattatt aattgacaat aattaaaatt ttcggtgctt tttagcacca
     3781 aaaatgagag tgtaatataa accgtgtaag taaccatcaa tcctaggcgg gtggttgctt
     3841 cacggttttt atttttctaa aataagatca agaggtgatt acacgatggc tagaaagaaa
     3901 agaaatcctg atgctgagaa gttagctgaa tccattttga atacttatca acccgaatct
     3961 gtagaggata tgcaagatgt tttaaaagat gtgtttggtc ccttatttga aaaaatgctt
     4021 caaggagaat tgaataacca tttagggtat gacgcccatt ctaaagagcc aaagaaacat
     4081 gacaatcgac gaaacggtta tggcaataag acgcttaaaa cgagctttgg taaagtaaac
     4141 attgatgttc ccagagaccg ggaggcttct tttgaacctg agttgattcc taatagaaaa
     4201 cgagatgtct ccgacatcgc agactgtaga caaaagctgt tccaaactcg taactcgagc
     4261 ttggaacagc tttttatcta cttcgtttcg aatttttgaa caaaaaaata aaggctcctt
     4321 gcctttccat agccaggtgg ctaatttctt taaattcatt gcagcaaaca ctagcatcgt
     4381 atgcgtcgcg actttttcca agcctcgata cttggtccaa cgcatcccat gcttttcttt
     4441 tgcatccgca aatattcgtt caatcgtttg tttccgtttt ttgtaaattg atttattcag
     4501 atctgttagg cgaagatgtt ccacttcatc catcagatct ccccaaacat gtctcgtgat
     4561 gactcgttga tgatttttac ttttggtaca ttggtttagc agaggacagt tcacacattc
     4621 ttttggattg gatttgtat
//
LOCUS       DAFEKH010000116         4615 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.122, whole genome shotgun sequence.
ACCESSION   DAFEKH010000116
VERSION     DAFEKH010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4615
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.122"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(15..962)
                     /locus_tag="LP386_002866"
     CDS             complement(15..962)
                     /locus_tag="LP386_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBL1920035.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(1140..1943)
                     /locus_tag="LP386_002867"
     CDS             complement(1140..1943)
                     /locus_tag="LP386_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HBL1920036.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            2089..3003
                     /locus_tag="LP386_002868"
     CDS             2089..3003
                     /locus_tag="LP386_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBL1920037.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            3051..3521
                     /locus_tag="LP386_002869"
     CDS             3051..3521
                     /locus_tag="LP386_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HBL1920038.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            3606..4214
                     /locus_tag="LP386_002870"
     CDS             3606..4214
                     /locus_tag="LP386_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBL1920039.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            4348..4548
                     /locus_tag="LP386_002871"
     CDS             4348..4548
                     /locus_tag="LP386_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL1920040.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
BASE COUNT         1511 a          716 c          911 g         1477 t
ORIGIN      
        1 attgttttca gctattaata tcctgcagac aattttactt gattggtttg aagctcatgg
       61 gtggcaaagt agcttttcag attggttaaa aaaatagcca ttaatttctt ttgaaaatca
      121 ggtgtcaaac ctgcaatgtg ggaagtaatc agtacattgt ccattttcca aagaggatga
      181 tcttgtggaa gaggctcttc ctcaaaaacg tctaatgctg caaaggaaag ttgctggtta
      241 tttaaagcct gcaccagatc ttgtgtctta acagaagcac cacggccaac attgatgaat
      301 acagattttg gatcaaagtg ttcaaacata tgctgatcaa agagcccagt tgtttcctcc
      361 gttagaggta agatattgac tacgaaatct acttcaggaa gaacttcctt tagttgattt
      421 aaagaaaaag tcttttccat tccttctgct ggatgaccgg atgtattgat tccatagcag
      481 ttcatgtcta atgctttgca tttttttgca atcatttttc caatatggcc agttccaatg
      541 attagtattt ttttcccttg gatagattgg taatggaccg atgaacctaa ccatttcatg
      601 tcactctgtg ccttttgtgc ttgaaaaaga ccacgagaat acccaaggat gattcctaag
      661 acatgctccg taatcgattc actgtggatg ccactaccat ttgaaagtaa aatatgtttc
      721 tttgaaaaag tctcaagggg tagctgatca acaccagctg agatagattg gacccatttc
      781 aaggtagaag aggctaatag tttttcttgg tagtctgagt tccagcccaa actgatctct
      841 acattttgta gatcctctgg ttgtaattct gttttaaaga tataaccagg cgctatagta
      901 tggatttctt cgataaattc atcacgaaat ggacgatctg cataaatgat tctttctgac
      961 atagttaatt tcccgccttt ctttactcta agtgtagcgc atacaagaag aactttgaag
     1021 cgccttgctt gttttttgag aaagaaatat ttttcaaata aaaaaggggc tgtgacaaaa
     1081 aaatgtcaca acctctaaaa gggtctattg aagtagaaat aacgagttgt ctttatttct
     1141 taattgatcg atatttttgc ccatcctttg acagcttgag caaaaataaa gattcctgca
     1201 aaagcaatga aggcgctagt gtcaaaagaa ggaagaaaga ccatcaagat tgttgcaatt
     1261 atagtaggca atgaaattga atagatcaat gtttttaaac aatcaagaaa agtagctttt
     1321 gttagtcgaa agcgtgcata gagaaaagca gcaatgttgg taaatagcaa agtgatcagc
     1381 agattcagaa aactaggata aatagaaaat ataaatgtca ggacttttat ccaaagtggt
     1441 atagatgctt cacttaaaaa agaacggagc tgcttacctg ttaagttttt taaagattca
     1501 ttggtgtagg gaagttctaa ttggttattg ttcaacaaag cagaagtcgt gcctgtatta
     1561 ggaagagcta tgataagttt gttttttaac atcccgacac taacaaaatt ccccatcaaa
     1621 tcagtagaga tgtcctgttc tgttcgtttt ccctctggat caaatgtgaa gataatggag
     1681 tttgtttggt aaatgaatcc ttctttttct tcggtttgaa gctgcccgtt ttggattgta
     1741 aaatcaggaa tgcgagtagc aatcttttgc ccatccaatt gaatgttgtt taagacttga
     1801 aaaacttgaa aagagattgg caaagccata attatactca aaactaaaag atagacaatg
     1861 gctttccaaa atgggacatt tctcgcctcc tttaggtctt tgaatcgtat aaaggaactg
     1921 ataattaatt gttttgttgt cataagtact cctcatctag tagtgtcatc acttgcaatt
     1981 ctagcgaagt atcaagtgaa atacaagtgc tttaaggaaa cagctgaatg attggtgaaa
     2041 tatcaaaaaa atgttattct tgtctaaaga ctatccaata taaataaaat ggaggaagga
     2101 atagtgccta cacagccaca gagatcatca aaaaaactat ttggagtagt ggttttgaat
     2161 gcggtgatca ctttatcaga atttattgga gggattatgt cagggagttt gtctcttgtt
     2221 tcagatgctt tccataacct tagtgataca ttggcaatta ttttttctta cggggcacaa
     2281 aaaatggccc gaaaagaagc aaataaaaaa cgtacgtatg gctaccagcg tttagaaata
     2341 ttgagtgctt tcatcaactc attcatattg atcatattat ccttgttttt aaccgttgaa
     2401 gcattcaagc ggttcacttc accagaaaag ataaatagtc atttgatgct aacagtagca
     2461 gttattggat tgctcgcgaa tttgttctca gtattattat tacgacaaga agcagatgaa
     2521 agtttgaata taaaatctag ttatttgcat ttgttaagtg atacactgtc ttcggtaagt
     2581 gtgattatcg gagcaatttt gatccgtttt ttcgatatct actggatcga tccagttatt
     2641 acactgatca tttcgatata tatattgata gaagcgataa tggtgatcaa aaaagctgcc
     2701 gctattttga tacaaagtgc acctgctatc gactatgaaa aaatggaaca agaaattgaa
     2761 gcaatcgatg gggtaaagga tgttcatcat gtccatattt ggcagtatag cgaaaagata
     2821 attattttcg acggacatat tgattttgaa gatcagctac taagcgagat tgaaaagata
     2881 tatcctcgta taatttcttt attaaaatta aaatatggta ttacacatgt gacgatccaa
     2941 gcagagacaa aggcaaagga tcaaaaaaaa ttaatttttt taaataaaga tgaaagttat
     3001 tgaaatatag agtatgataa ataagaattt ttaataaggt aggttggctc atgaagcagt
     3061 atcgacagtt aaaaggatat ttagaagcaa aaggatattg ggagatacta gtctatctct
     3121 tttttggtgg tttggctacg attgtaaatt ttgttagttt tgctctcgca cgccaatatt
     3181 ttgatttaag tatggcctta tccaattcta tttcgtggtt ttgttctgta ttgtttgctt
     3241 ttgtaacgaa caaactttgg gtattccatt caaaatcacc gaattttaca catgcactta
     3301 ttgaatgcgg taagttcttc ttctaccgta tcctttctta cggattggac atgggggcaa
     3361 tggtattgtt gatcaatgtt atgaacagca atgagtatgt ggcgaaaatc atcactcaaa
     3421 ttattgttat ccttgcgaac tatattttca gcaagttgtt tatttttaaa gaaactgagg
     3481 tttttgaaga agaagtaggt caaagtgaaa aagacgacta ggcataacaa ttgaagaatt
     3541 tccttctctt tgttactctt tgtaatgtag acattattaa gaaaacattg aggaggaatt
     3601 tttttatgac ttacacatta ccagatctac cttatgcata tgacgcattg gaaccttata
     3661 ttgacgaaga aacgatgcat ctgcatcatg ataagcatca caatacttat gtgacgaatt
     3721 taaattcagc aattgagaaa tacccagaat taggcgaaaa aacaatagaa gaattattat
     3781 ctgatatgga cgctattcca acagatatca agacagctgt acgtaacaat ggtggcggac
     3841 atgctaacca ttcatttttc tgggaaatca tggcaccaaa tgctggtggc gaacctacag
     3901 gagaaataaa agaagcgatt aatgaagctt ttggtgattt ttcttctttt aaagaagaat
     3961 tcaaaaaagc agccgctgga cgatttggtt ctggatgggc ttggcttgta atggaaaatg
     4021 gaaaattagc tattacctct actgcaaatc aagattctcc attgatggaa ggaaagacac
     4081 caattctagg tttggacgtt tgggaacatg cttattattt gaaatataaa aatgtccgac
     4141 cagattatat tgcagcattc tggaatgtta ttaattggga tgaagtaaac aaacgtttcg
     4201 aagcagcaaa ataaccattt cctccgtcat atcagtctta aaaataattt ggaaaataaa
     4261 agagcgaaag cttgctagcg ttttctaaat tgggtataat gttcttgcaa ggttacttgc
     4321 aagaactttt ttggaggata tacatttatg gaacacggaa cggttaaatg gttcaacaat
     4381 gaaaaaggat ttgggtttat tacagtagac ggcggagatg acgtatttgt tcatttctca
     4441 gcaattcaag gagacggctt caagagccta gaagaaggtc aagaagtaga attcacgatt
     4501 gttgaaggtg cacgcggacc tcaagctgct gaagtgacta aattataata atttgttgaa
     4561 taaagacacg acttcttaga gagtcgtgtc tttttgtcta tttatgaagt tttta
//
LOCUS       DAFEKH010000117         4543 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.123, whole genome shotgun sequence.
ACCESSION   DAFEKH010000117
VERSION     DAFEKH010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4543)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4543)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4543
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.123"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..306)
                     /locus_tag="LP386_002872"
     CDS             complement(<1..306)
                     /locus_tag="LP386_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1920041.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRIGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     "
     gene            980..1792
                     /locus_tag="LP386_002873"
     CDS             980..1792
                     /locus_tag="LP386_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920042.1"
                     /translation="MILLAVSMSLLIYTHILSTFMSVIVIGFLFIGSLFSKRKERKEM
                     SNLISNMIKAVGWTILLTAYVWYPMLQQVLHQKINRPFRTKLQERALNISDSLIGAVN
                     NDLVTFTMGTIGVVSFILPLFFKKKFANKEKIINFCAVTTWFLSTNLFPWEFLQKTPI
                     QIIQFPWRILGFQVLFGSLILIIVFLKWKTSNKKSMCSLVGIVLLIFTVTVATEANYS
                     QKIQSYKGRLIMTKKDVTLYTTSRTGGLYDYAPLDALKYKDHLKKHEVKVYD"
     gene            3427..3981
                     /locus_tag="LP386_002874"
     CDS             3427..3981
                     /locus_tag="LP386_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL1920043.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGG"
     gene            4235..>4543
                     /locus_tag="LP386_002875"
     CDS             4235..>4543
                     /locus_tag="LP386_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920044.1"
                     /translation="MINSAYFHIKYLKKYEYEEVVLDYGLNRQSFLIYAINNGNLPSN
                     KKNIIIETYAYLEGGSKKLIKSCNIEYQLSVGEIKCVFEEDLELDLKKIFASIHDYIG
                     L"
BASE COUNT         1631 a          579 c          730 g         1603 t
ORIGIN      
        1 ggctttttcg tttcgttgat aacgttcaaa cactgtgggt gaaaaatggc catcacgtgt
       61 tctgggtact tttaattcta gcgtgcctat acgtgtcgta aagctgcgct cataatagcc
      121 atttcgttga ctttgtcggt tttctgttcg ttcatattct tttgcttgaa tatattctgt
      181 tcgttgattt tccattagtt gattaaatac cgttgttaaa atatttttag aaacgtcatc
      241 ctttacagaa tattcaataa tgctttgaat ctcttcgctt ttcagtgtaa aatgtacttg
      301 ggtcatgtaa aagtcctcct gggtatgttt ttgtcgttaa aaacattgta ccgtaaaagg
      361 actgttacat ggccttttta cttttacaca attataagga ctttatcgaa aaaaagcagt
      421 tatttgttaa aatcattgat attattaata ataagtattt tttgaaaggg gaaatataaa
      481 aggtttttga aaataaataa aaaatagtat tacttgttct attgctagtt attgctagtc
      541 tttattcttt tttgtttttt agggatgtac aaaagatctc aaccacagga gacattgctt
      601 ttcacttttc tagaataaaa tgcttgtcct cagtattttc tggtccaata aattttacca
      661 catttaatag ctatggcgga ggcgtgaatt tttttatcca tatctaacat ctttccagcc
      721 gtaatatttt actggacaac aaacaatttg attctaagtt atatacttac tatacgttgg
      781 gatactgaat atctgtacaa ttctagtgag ctatcaatat ggacaaaaga atagatgcag
      841 ccttcttatt cagctgtttg tatagctttt atggattgat atatattagc gtactgcaat
      901 ttcagaatca attgcgttga cgattgtacc agttgtcttg tattacacat atactcttct
      961 ttatgaaaga aaaaactgcg tgattctttt agctgtcagt atgagtttgc tcatctatac
     1021 ccatattctc tccaccttta tgagtgtgat tgttattggc ttcttgttta tcggctctct
     1081 tttctctaag cggaaagaga gaaaagaaat gtcgaatctg atatcaaata tgataaaagc
     1141 tgttggttgg accattcttt taacagctta cgtttggtat ccgatgttac aacaagtcct
     1201 acatcaaaaa attaatcgtc cttttcgcac aaaacttcaa gaaagggcat taaacatttc
     1261 tgatagttta atcggtgcag taaataatga tttagttaca tttacaatgg gaacaattgg
     1321 tgtggtttca tttattcttc cacttttctt taaaaaaaaa tttgccaata aagaaaagat
     1381 tattaatttt tgtgcagtga ccacttggtt cttatcaacg aatctttttc catgggaatt
     1441 tttacaaaaa acacctattc aaatcattca gtttccttgg agaatcttgg gttttcaagt
     1501 gctttttggt tcattgatct taattatagt gtttttaaag tggaaaacaa gcaacaaaaa
     1561 aagtatgtgt agccttgtag gaatagtcct tcttattttt acagtgactg tagcaacaga
     1621 agcgaattat tcgcagaaaa ttcaatcgta taaaggtcgt ttaattatga ccaaaaaaga
     1681 tgttacactt tatacaacct cgagaactgg aggtctttat gactatgcac cattagatgc
     1741 attgaaatat aaagatcatt taaagaaaca tgaagtaaaa gtctatgatt gatgggagaa
     1801 tgcatctcat aaagcacata attctaaaat aatctataca gtaggagatg cgaatgagca
     1861 aaatatcacg ttacctgtat ttaattactg ggaacagtta tgaaagtaaa tgggaaaaag
     1921 agcactatag aaaatgacaa tggtttagtg tctattaaag gtacgggaaa aagaactata
     1981 gttgaggttt catctacgta tccaactacg atgattctat ctttattaat tagttcaata
     2041 acttttatat tcttatttac acgttattta ataagatgct gcggttaaat gaaaatagat
     2101 tagatagata ttataaatat gttgattcta ttttcatagc aatggagaaa atacattagc
     2161 aatatataaa agaaggtatc aagagtcacg gtgaatttat tccgaaaagt gaaaagaaca
     2221 aatataaaat ttaataaaaa tatagaacta aataggaaaa cgtagacgta attttctacg
     2281 ttttcctttt catatatatt aaatattacg gaaatttata taaactaatt tagtgttttg
     2341 tttgtaattc ctaattttgc tccactttta gataattttt aggtctattt aactcatcag
     2401 acattctatg ctcattttct ccaaatttgt ttcaactctt tcgtacttaa ttttgcgtat
     2461 ttgaaaattc ttcttttaga gtacttttat tacgatacta gtatgatata tatctatagc
     2521 aaacagttaa aatcttccta aaataagcga atagcattcc taaaacctat aaaattttta
     2581 gatgaagcga caagtggaca attaataaac tacttgaaca tgaaattatg gatcaccttt
     2641 caaatttaga aaatggaatt cttatactta ttgcgcaaca tttattgatt gcaaaattat
     2701 gtgacaaaaa gaactagtag aagaaggaat aatggcttga taataaagta ctacctatta
     2761 aaggtagtac tttatttaat ttagtataaa ttaacatact actatatttt aagtttcata
     2821 ttatataaat taataatata ctaccatttt ttggtagtat aatttaaagg taataagtta
     2881 ttcttttatt actatgtttg ggttttatag caaggaaagt ttaataagag tttggaccta
     2941 gcaaacaata ttaatgaggt cattaaatct tattatcttt agtgatataa cgaaatatct
     3001 acacagacaa aattatgatc ttgcgtaaag ttataaaata ttaataaaaa tattttatta
     3061 atgaaaagct tggtagcacg gttattcata tgctaattta tttcacttta tagtaagggg
     3121 agttcttagt atattgtcca aatttaaatt tcatataatt taattatgta aattagctat
     3181 tctaagaact tctacggata actgcccgtc taaaatttaa ttaagagctt agaatcttca
     3241 tataagtaag gttaattttt ttgtacaaaa tagtcggaat attctgagtt actgaaatga
     3301 tataaaatca taaactaaac cccttgattt tcttcacttt taacagagta tatatataag
     3361 ttcatgatta tggtaaaata tatatataat catgaactca gaatattttt aagaagggaa
     3421 acaatagtga gctataatgt acaaccgtta aggacaaatg aagagataca agattttcag
     3481 ttttggctaa gaagaacaag taatccagaa agagatagtt ttttattttt gtttggaatc
     3541 aataatgggt tacgtatgtc agatattata ggattaaaag ttggagacat acgaggtaaa
     3601 agtaagccta ttattgttga acataaaaca ggtaagcgaa aaccgatttt tatagataat
     3661 ttgagagaag agattttatt atatactgaa ggtaaagaag aaaatgattg gttatttcca
     3721 agtcggcaac aaggtcgaca tataacaagg gatcgtgtct atcagatata tgcagatata
     3781 gcagaaaaat taggaagaga tgatatagga acacatacat taagaaaaac ttttgggtat
     3841 cactactaca agaaaactag agacattgct accttaatgt ttatttttaa tcatagctcg
     3901 caagcaatta caaaaaggta cattggtata actgaagatg aaataggggc atcgttacgt
     3961 ggttttaaat tgggaggcta attgagatat taggatatat tttttgtgta taatgaaaac
     4021 ttagaaggtg agattaatga agataactga attttcggaa gtatttaaaa cgtttagtaa
     4081 catttacaat agaataccag agatagaaca aaatgttgta gttgataatg attattatat
     4141 agagaatgat tttaataaac caagaaaata tgacaaccta tacaatttta tacacaatag
     4201 aacaacaata aataacaaca gtaacactcg agttttgatt aattcagcat attttcatat
     4261 taaatattta aagaaatatg agtatgaaga agttgtatta gattatgggc taaatagaca
     4321 gtcattttta atttatgcaa taaataacgg aaatttgcca agcaataaaa agaacataat
     4381 tattgaaaca tatgcctatc tggagggggg atctaaaaaa ctaattaagt catgtaatat
     4441 agagtatcaa ttatcagtag gagaaattaa atgtgttttc gaagaagatt tagaacttga
     4501 cttaaaaaaa atttttgcca gcattcatga ttatataggt ttg
//
LOCUS       DAFEKH010000118         4476 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.124, whole genome shotgun sequence.
ACCESSION   DAFEKH010000118
VERSION     DAFEKH010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4476
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.124"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(832..1125)
                     /locus_tag="LP386_002876"
     CDS             complement(832..1125)
                     /locus_tag="LP386_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HBL1920045.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            complement(1528..2705)
                     /locus_tag="LP386_002877"
                     /pseudo
     CDS             complement(1528..2705)
                     /locus_tag="LP386_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(2809..3123)
                     /locus_tag="LP386_002878"
     CDS             complement(2809..3123)
                     /locus_tag="LP386_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1920046.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            3230..3445
                     /locus_tag="LP386_002879"
     CDS             3230..3445
                     /locus_tag="LP386_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920047.1"
                     /translation="MKQGIADIKIIKEILEKSTANAIAFGTGINLSTVKKLKSGERAE
                     EKLNLADAIKITEFGMKNMPTKIEIWK"
     gene            complement(3745..3987)
                     /locus_tag="LP386_002880"
     CDS             complement(3745..3987)
                     /locus_tag="LP386_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1920048.1"
                     /translation="MKQNKRYIPFIPLTTIKAAASGDSIAMSIVLSKYQNYISRLAMK
                     PVYEEEKGMVMYVDEYMRRQLETKLIEKILEFDTTR"
     gene            complement(3974..4402)
                     /locus_tag="LP386_002881"
     CDS             complement(3974..4402)
                     /locus_tag="LP386_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBL1920049.1"
                     /translation="MGDSEETHIQHTFDSFCKKVVCNEALNIQKKYARFRQRQISMEI
                     LEQKGLGTEFYYLEPNLNSSGTFIVLGMKIFISNEELANAIAALPSQRQEIIFMSFFI
                     GLNDREIGDIIGKSLGSVWYQRQMALEELGKYLGVKYEAK"
BASE COUNT         1418 a          842 c          663 g         1553 t
ORIGIN      
        1 ataaaaaatc atcaaataat cctttacacg ttattctaaa tttaattttt attattttat
       61 tgatgtatag aaagtttggg gctttttttc tctttttatt ctaaggttat tttagtcttg
      121 tcctttaata caaagatttt atttttaaat aaaaaatact ctttttttac gattattgaa
      181 aaaaaaagat aaaacttgat taattgaagt attgcttaaa tttggaagct atgagggaag
      241 aataaaagag ttaggacggg attatctact atttttcttt gttttaaata tttgttatct
      301 ttgaacataa aagagaaatg tgtcgactgc agtgttgtgt ccctcatcac gaataaacgg
      361 tgttcaacta gctgatcttg tattcactta aaaaatggta aagtacgagt tgctattccc
      421 cattttcaat tttctaacgc tcaggacaaa atactgtttt cacaacctca ttggaataaa
      481 agcatatata ttgtttcaag aacgaaatct tgttatcttt ttaaagggca tctgtccaaa
      541 atctaatttt aggaggtacg ttttggtatt tattcgtaca aataaaagag aattatcttt
      601 attcatgtaa cgcatccaat tgattttttc atgtacgctc ctggaacgat tttactgacg
      661 attgcttatt taactgcgaa tcgctcatta gcttttatca tagctatcca tattttgaat
      721 aacgttcttg gctttgtatt atagatacag atgacaaaaa aagttcaagt atgcggtgta
      781 gaaccaatat cgcatacttg aacttttttc aatgagtata aattaaaact tctaattttc
      841 aattcccatc atctgatatg cccgaccgtc tgaacttctt ttgaaaaagc caaatgtgat
      901 tagataacgt ctttgttcga cataatcgcc actagaaaat acgttcagca gtatcgaatt
      961 aacctctgtt tctgtataag tcactccatg gtcaaagcgt ttcaagactt ctttcaatag
     1021 gatgtatttc ttttttgttg aacttggtac ttgttttact tttccatcat tcatgaatgt
     1081 gtctaaaact ttcatctttt cttgctccgt ataagtataa accatcttct ttctcctttt
     1141 gattctaaga atactccatt tatgttagaa tattctggat tttttattaa agcggttact
     1201 cttaagaaag atattatcat agtgctcttt tttttactac tacttatagg tagatttatt
     1261 ctaatccatt attctcccct accaataatt aaagaaaaaa ctggatcagg gtgttcaaat
     1321 tacatgctaa gaaaaaagaa cccttgaata ccaagggttc tttctcagtc tgataacaat
     1381 gattaacgac ggatttcttt gatacttgtg aaaagtcgtt aaagtattga tataaaagga
     1441 tttttattac ctctgactac atattgacta atttgttaaa aaatcgtttt tcaagaatcc
     1501 tgtaatacca gtgctttcac cgttttttta actctctaaa gaactaaaag caatcagagg
     1561 ttttaccttt tcatttgacg ttaagtggcg ataaattttc gaagttgttt ggtcagtatg
     1621 gcctaagcga tctttcaaga cttcccagct acagtgttcc gctactaagc ttgccattgt
     1681 atgacgagct aaatgagtat gaaatggctt attaattcct gagcgattca cgcaccgttt
     1741 gacgtgatca tttacatact ctcgacgata aggaacacca cgtttactag aatcaagata
     1801 cacaaacaaa tatgtttctt ctataataaa cctgtaatgt tgcctcatct cacccaaagc
     1861 cttaatcaac tgttgtagct tttccataac tagaggagtt actagaactc gtctagcaga
     1921 actaactgtc ttagtagttt caattcgaaa atccttactc ttacctttaa ctgccgtttg
     1981 cttatagaac agaatttcat ttcttttgaa atctatatct ccaggctgta gagcaagcgc
     2041 ctcgctgact cggcagccag tgtaaaatag aacatggaaa agtacagaca tcggtaattc
     2101 ctcatgaaca atgccataat tcaaaaaagt tctcaattca tcgacagtaa gaaacttgtc
     2161 ctcaatatta tttatggctt cttttaaatc agttaccgtt aactgatatt ttggcattct
     2221 cacagacttc attggatttt cacttatcaa attctttctt tgacaatatt taaaaatcat
     2281 atttagaact tgaataagtg attgtaaact atttttggca tagccaacat ttgttccatt
     2341 aacgccacat tcctttaagg taaaaagcaa ttcttgaagg cactctggtg tcaaatcaga
     2401 caacttttta tcaccaatcc atcgaacaat aatttttaat tgttcctctc gcttatcata
     2461 ggttatttcc ttttgttcat ttaacgaacg gtaatattgg aaccattgct cacctacaac
     2521 actaaacttg tcattgcttg caacaatttt ttcttaagcc tttgttgttt ctccatttcc
     2581 agataagcga gttgcgcctc acgttttgaa ttaaagccac gtcttgttgt tcgatatgct
     2641 tgaaagtacc atgtgatcct accagtagaa ctgatttgct tcttgaatcg atctgttttt
     2701 tccatttatt gattcctcct attttgaagg aacccaacaa gcagaaaccc tttggaaatc
     2761 tttctatcta tgtcatcatt gtaccgcatc ttagaaagaa aatgtaactt ataaagatcg
     2821 aagtagtcgc aatttttctc gatagtcatt cgaatcactc tttctcatcc attctaaaac
     2881 atcatcacga aaatagtgtc ctcgaatccc gtaccaacag ggaggaaact caccaagttt
     2941 tactaaacgg ttcagtgtac tatcacttat ctgaaatagt cgctttaaat cagtatttgt
     3001 taataccaga ggtaaatgac tgactgcaag caatttttcc gtgtaatctt ccagtttttt
     3061 ttgtaaaatt gaatagaact ctatttccag agaattaaca tttgttttaa cttccaactc
     3121 catcaccctt ctctctcaaa atcaaaacga ccaccacggt accccttaaa attgtaaaaa
     3181 aacactccag tactccatca aaacggacta gaaaagagga atttttaata tgaaacaagg
     3241 aattgcagac ataaaaataa ttaaagaaat tcttgaaaaa tctacggcta atgcaatagc
     3301 attcggaaca ggaatcaact tgagtacagt aaaaaaactt aaaagtggag agagagctga
     3361 agaaaaatta aatcttgccg atgctattaa aatcacagaa tttggcatga aaaatatgcc
     3421 aaccaaaatc gaaatatgga aatagtagtt tttctgatct atcagctgtt ttgccaaagc
     3481 acataggaat ctcacctccc cccagtaatg gcgggccgat ttggttacgg aagtatcatt
     3541 atcgtagtcg cgattctcat attaaaattt gtcgcttaaa agctaacctt gtcatggcgt
     3601 aactagagaa tcaaaatcta catgtactga tagatttgct attcatttgt caaagagcgc
     3661 taggctattt tcagcctatg gaaatccttt attttgaccc gataaaaaac ttccatagaa
     3721 tgaaaaggaa agggaaaaaa tactttaacg agttgtatca aattcaagta tcttctcaat
     3781 caattttgtt tccagttgtc tacgcatata ttcatctaca tacataacca ttcctttttc
     3841 ttcttcataa actggtttca tggctaaccg tgaaatataa ttttgatatt ttgacagaac
     3901 gatggacatg gcaattgaat caccagaagc tgcggctttg attgtcgtta gtggtatgaa
     3961 tggtatatat cgtttatttt gcttcatatt tgacacccaa atactttcct agctcttcca
     4021 aagccatttg tcgttggtac caaacactgc cgagactttt cccaataata tcgccaattt
     4081 cacgatcatt aagaccgatg aagaaggaca taaaaatgat ttcttgtctt tgactaggta
     4141 atgctgcaat cgcatttgcc aactcctcat tggaaataaa gattttcata ccaaggacaa
     4201 taaaagtacc actactattc aaatttggtt ccaaataata gaactctgta cctaaccctt
     4261 tttgttccaa tatttccatt gatatttgcc gttggcgaaa tctagcgtac ttcttttgaa
     4321 tatttaacgc ctcattgcag actactttct tacaaaaact gtcaaacgta tgttgaatgt
     4381 gggtttcctc tgagtcgccc ataatattct ccccctcaaa aaattcattc aactcgtttt
     4441 acttctatcc ctttccatta ttactacaat ctagga
//
LOCUS       DAFEKH010000119         4400 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.125, whole genome shotgun sequence.
ACCESSION   DAFEKH010000119
VERSION     DAFEKH010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4400
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.125"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(98..1618)
                     /locus_tag="LP386_002882"
     CDS             complement(98..1618)
                     /locus_tag="LP386_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBL1920050.1"
                     /translation="MTKMESELLVQIKQLTQLLEIQQQENTLLREQIAEMNRRLFGRK
                     KETPPVDGQIDLLDDSTFNEPEHTGQESQEPITVSSFKRRKRKGLKALSLEGLPEVPI
                     HYELKGADCLCEDCGHTLHDIGATRLREEPLYVPAHIEKQVIYQHAYHCRECEALGET
                     KIKKAPVPKPLINNSLGSSSIVTQSIWEKFVKKVPAYRQEKEWHALGFPLDRKKITNW
                     HIKVSEMVLEPIYNCLHQELSNQEVLHADETSYRVLNTHKEKTFYWLYASGKSEEKQV
                     VLYEHANSRSVDEPKSFLESFSGFLHTDGYAAYGKLPVNNVYCWAHVRRKFFEALGKQ
                     PSPKSHAKIGLDFCDKMFRIERTFNKLSAEERFVARKETLQPVMTEFFHWCESFAYLP
                     KSQLGKAVQYAVNHKDGLQIVLLDGRLELSNNRAERAIKELVIGRKNWLFSKSLKGAR
                     SNGIILSIIQTAVANGLNIRKYLNHLFTEIPNLSSMTPEALRAYLPWNQQIQEICK"
     gene            complement(1861..2046)
                     /locus_tag="LP386_002883"
     CDS             complement(1861..2046)
                     /locus_tag="LP386_002883"
                     /inference="COORDINATES: protein motif:HMM:NF017528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HBL1920051.1"
                     /translation="MPMLIDATALKHIFIVCGKTDLRKGIDGLAAFVIEEYDLDVYDQ
                     ALFLFCGTKKDRFKALY"
     gene            complement(2030..2212)
                     /locus_tag="LP386_002884"
     CDS             complement(2030..2212)
                     /locus_tag="LP386_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920052.1"
                     /translation="MNKKDIVPVQFSSAAQKSQIDTKPKLACRIKSEDKEIFIYNGMD
                     KYLLYTLLKELNANAH"
     gene            2453..2671
                     /locus_tag="LP386_002885"
                     /pseudo
     CDS             2453..2671
                     /locus_tag="LP386_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            3166..3765
                     /locus_tag="LP386_002886"
     CDS             3166..3765
                     /locus_tag="LP386_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL1920053.1"
                     /translation="MKTVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLADVLEISRGRVVVKDRLAMKEQKTAKHNSVYISNKLRKTILEYVQQEFPDQ
                     LLQQDFDGYLFPSRKGTNEPLNRQSLWRIIHDAGTAIGLKDIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            3829..>4400
                     /locus_tag="LP386_002887"
     CDS             3829..>4400
                     /locus_tag="LP386_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriophage abortive infection AbiH family
                     protein"
                     /protein_id="HBL1920054.1"
                     /translation="MSTLYIIGNGFDLSHGLKTRYTDFSKWVEKSHSEIFDKIDTMIN
                     ENNEVRSTADDKIGWFNFESSLHELIQSPVFEDYVEESKDYLIGYGHEDWSDSAHHDF
                     QNMVYDYVVSLEELQQLFKEWIRKEIQPTIEHKIPKYQFSSDVLFFTFNYTDVLEILY
                     KQPKENIYHIHGSYDDIIIGHSENFDNFIG"
BASE COUNT         1402 a          799 c          785 g         1414 t
ORIGIN      
        1 taattcagta gttttgagcg taagcgtgtc atagaatggt acctaaacac aaatagcccg
       61 atttgataca ctcaaatcag gttatttgtg gcttatatta tttacagatt tcttgtatct
      121 gctgattcca tggcaaataa gcgcgtagcg cttcaggtgt catcgaagac agattgggaa
      181 tctctgtaaa aagatgattt aaatatttgc ggatgtttaa cccattcgca acagctgtct
      241 ggataatact caatataatt ccatttgatc tagcgccttt taagctttta gaaaatagcc
      301 agttttttcg accgatcact aactctttga tggcacgctc tgctcggtta tttgaaagtt
      361 ccaagcgtcc atcaagcaac acaatctgaa gtccgtcttt atgattgact gcgtattgaa
      421 ccgcctttcc aagctgcgat tttggcaaat aagcaaaact ctcacaccaa tgaaaaaatt
      481 cagtcatcac aggctgcaac gtttccttcc tcgctacaaa cctttcttct gcgctaagct
      541 tattaaaggt ccgttcgatt cgaaacatct tgtcacagaa gtctaatcct attttggcat
      601 gactttttgg ggacggttgt ttacccaatg cttcaaaaaa ctttctgcga acatgcgccc
      661 aacaataaac attgtttacc ggcagctttc cataggccgc gtaaccatca gtatgcaaga
      721 aaccgctaaa tgattctaaa aaactttttg gctcatcaac ggaacgcgaa tttgcgtgct
      781 cgtagagcac aacttgtttt tcttcgcttt tacctgaagc atataaccag taaaaggtct
      841 tttctttatg agtattcaat acccgatagc ttgtctcatc cgcgtgtaag acctcctgat
      901 tgcttaattc ttgatgaagg caattgtaga ttggctctaa aaccatttca cttaccttga
      961 tatgccaatt agtgattttt ttacgatcaa gagggaaacc aagtgcatgc cattcttttt
     1021 cttgtcgata tgccggcacc tttttaacaa atttttccca aatactctgt gtcacaattg
     1081 aagaggaacc tagactatta ttgatcaacg gtttaggaac aggcgctttt ttgatttttg
     1141 tttctcctaa tgcttcacat tctctgcaat gataggcatg ttggtagatg acttgttttt
     1201 ctatatgggc aggaacatac aatggctctt ctctaagcct tgtcgcaccg atatcatgta
     1261 aagtatgacc acagtcttca cacaaacaat cggcaccttt taattcataa tgaataggaa
     1321 cttcaggcag accttctaat gaaagtgctt tgagtccctt gcgttttctg cgtttaaaag
     1381 aagataccgt aatgggttcc tggctttctt gtccagtgtg ctctggttca ttaaaagttg
     1441 agtcgtctaa taaatcgatt tgcccatcta cgggtggtgt ttcttttttt cgtccaaaca
     1501 agcgtcgatt catttcagca atttgttctc taagaagagt attttcctgt tgctggattt
     1561 caagcaactg tgttaattgc ttgatttgta caagaagttc agattccatt tttgtcattt
     1621 ttacaccacc attctagcga ttttcttaca tctattatac cattttatga caacgaaaaa
     1681 cagacaaaat ccttgattta acaaggtttt cgtctaatat atcgcacctt ttttcgtttc
     1741 ttttagcgta catttttctt cgattgaaag gccagtcagt aagacttctt ttctggaacg
     1801 cggccattga aggtacccac tttcaaatct tttgtacatt aatacaaatc cattttgatc
     1861 ctagtaaaga gccttgaagc gatctttctt cgtaccgcaa aataagaaaa gcgcttgatc
     1921 gtaaacatca aggtcatatt cttctataac gaaagctgct agtccatcaa ttccttttcg
     1981 aagatctgtt tttccacaaa cgataaaaat atgtttcaat gcagttgcat caatgagcat
     2041 tggcattcaa ctcttttaac aaggtataca aaagatattt atccattcca ttataaataa
     2101 atatttcctt atcttccgat ttgattctgc aagctagttt tggcttggtg tcaatttgcg
     2161 atttttgagc cgcacttgaa aattgaactg gtacaatatc ttttttattc attcgttttt
     2221 ctccttctat atttgatagt ttaattatag aagaaagata atcggcgtac gagatactat
     2281 cctatgacac gcttacattt aatttaatat tttgcctcaa attagccaca ctttttatag
     2341 aactaagagg aaaaatgaag ttttcttcct attaatatag ttgtttgaaa tcttaaatat
     2401 agcgttttac gatgtaatgg gaagtatggt gaataaatca actatgttcg tacgaagcat
     2461 ttactcaact aatttaatcg aatctttcaa taaacaaatc aagaaataca gccaccgcaa
     2521 ggaacagttc caaaatgaag agtcgatgga acgtttctta gtctcgtctt ttgatactta
     2581 caaccaaaaa ttcctaggtc gcagtcataa aggtttccaa caggccgaag gcgagctcga
     2641 acaaatgctg agtcaaccga tggagaatta gaaacaatct acagtaggga agaaccattg
     2701 acacaaaatt attgacgctc ccaactaaaa gtgtcaaaat aatgatgaaa tcatttagtt
     2761 cttataaatt agaaaagaga aaataaatat tccatatcta ctttattgga tccgtaacat
     2821 gactaaattc tgaatacttt ttaaagctta tcatttggta aaactgaata taagttaatt
     2881 atatagactg aaaattttga attttcagaa tagaataact taaaagtact gacaaaattt
     2941 tttaaagggg caatattaat gttctgagat aatcaaatcc taccgaaaat atcaaaaatc
     3001 caatgtgaca caatcagatt gtgtctcatt cgagggaatc acacaatccc acgtggctct
     3061 aggcagaatt gaatttttgc ttggggcttt ttccttatat tgattttgaa tgagacttat
     3121 tatatgttat aatgcaatta agtatcattg gagagggcga agaaaatgaa gacggtagaa
     3181 cctattcgag acaaaaaaaa gatcgatgcg atgaaggcaa tcttggcttc gggaaaatat
     3241 ggccaacgaa atttggttct tttttcgatt gggatcaaca ccgcctatcg catttctgat
     3301 ttgcgtcaat tgaagctggc cgacgtgctg gaaatttcac gcggtcgcgt ggtggtcaaa
     3361 gatcgattag cgatgaagga acaaaaaaca gctaaacata attcggtcta tatttccaac
     3421 aaattgcgaa aaacgatttt ggagtacgtt caacaggaat ttcctgatca actccttcag
     3481 caagattttg acggttattt gttccctagt cgaaaaggga cgaatgaacc gctcaaccgc
     3541 caaagtctgt ggcgaatcat tcatgatgct ggcacggcaa tcggattgaa agacattggc
     3601 ccacattcca tgcgaaaaac gttcggttac tttctctata aacaggggac caaaacagaa
     3661 atcattcagt ccttgttgaa ccattcttct cagcgcgaaa cattgcggta tattggtatt
     3721 acacaagaag acaaagatac agctgtaaaa agcttagatt tataatataa aagttaagtt
     3781 taaacatgga tagttttaaa ttagtagatt gagtgttggg aggaaagaat gagtacatta
     3841 tatattatag gaaacggttt tgatttaagt catggtttaa aaactagata cactgatttt
     3901 tcaaaatggg ttgaaaaaag tcatagtgaa atattcgata aaatagacac aatgataaat
     3961 gaaaataatg aggtgagaag tacagctgat gataagatag gttggtttaa ttttgaaagt
     4021 agtttgcatg agttaattca aagtccagtc tttgaagatt atgtagaaga gtctaaggat
     4081 tatctcatag gttatggaca tgaagattgg tcagattctg cccatcatga ttttcaaaat
     4141 atggtttatg attatgttgt ttctctagaa gaattacaac aacttttcaa ggaatggata
     4201 cgcaaagaaa tacagccgac aatagaacat aaaattccaa aataccaatt ttcgtccgat
     4261 gtactattct ttacattcaa ttatacagat gttttggaaa ttctatacaa gcaaccgaaa
     4321 gaaaacatat atcatattca tggcagttat gacgatataa taatcggcca ctccgagaat
     4381 tttgacaact ttataggaga
//
LOCUS       DAFEKH010000120         4157 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.126, whole genome shotgun sequence.
ACCESSION   DAFEKH010000120
VERSION     DAFEKH010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4157
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.126"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            179..775
                     /locus_tag="LP386_002888"
     CDS             179..775
                     /locus_tag="LP386_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBL1920055.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
     gene            899..2698
                     /locus_tag="LP386_002889"
     CDS             899..2698
                     /locus_tag="LP386_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBL1920056.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(2976..3188)
                     /locus_tag="LP386_002890"
     CDS             complement(2976..3188)
                     /locus_tag="LP386_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920057.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            3650..3799
                     /locus_tag="LP386_002891"
     CDS             3650..3799
                     /locus_tag="LP386_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920058.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            complement(4052..>4157)
                     /locus_tag="LP386_002892"
     CDS             complement(4052..>4157)
                     /locus_tag="LP386_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL1920059.1"
                     /translation="ASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
BASE COUNT         1227 a          708 c          729 g         1493 t
ORIGIN      
        1 tttaaaaaaa acaagttatt aaataagtct ttagttggat gtttttttga gatcaatctt
       61 ttatacttat gatgaactta caaaattgtt tgttttctgt catatcaaaa aatggcgcag
      121 ttagttgctt ttctagtaaa gtatagttaa caaagaacct ctaaggagtt gatgaataat
      181 gaatattgct gcctctcgaa aactgataaa tttcatatcc attatcggat taggcctatc
      241 aatcgcgctg acgatttatt ttattaattt aggtgttttc aaagatttga atgcgttaag
      301 aggattagta ggtgattcca tcattttagg accgattatt tttgtcttca tccaaatcct
      361 gcaagtagtt attccaatca ttcctggagg gatcagtact gcagctggtg tcctgatatt
      421 tggcccttat gctggattta tctataacta tattggaatc tgcattggtt cgattatcat
      481 ttttctgcta gggcgtcgtt atggaaagcc attcatactt tccatgatta gcgataagac
      541 atataacaaa tatattggct ggctggataa tcaaaaccgt tttgagaagc tgtttgctct
      601 agctattttt cttccagttg ctcctgacga tgcgttatgt ttgatggctg gattgacaaa
      661 catgtcagtg aaacgatata cactaatcat tttgattgct aaaccactgt cgattttctt
      721 atatagtatg gccttgattt atggaggtca atatctaagt ggtcttcttg gataatattt
      781 attttgtaaa attagtcatt gattgacaat gttaaatctg ggaaagggtc tgcaaaacac
      841 actgcaccct ttcctttttc attagatttg cgctacaatg tgaagagcag gtgataggat
      901 gaattatttg aaacgtagct taggtaatgc ttgggacttt ttaaaaggaa cacaagctta
      961 tttccgtgat gtcttgctga tgcatggctt tattttattt atttgtttac ccttattgag
     1021 cagtacgacc cgttttattt tacaccgagg ggcaattgac tatttgtctt atgacaatat
     1081 tccttcaatt ttttctcaac atcctggggt tctactctcg ttaatcgtag ttttgatgac
     1141 gattttactg ttagtttatt tcgaatttac ttttcttttg atgagtgttt tttttattaa
     1201 aaagaaagaa ccaatctctt tgaagcaact cttacacttg acgatacttc agctgaagaa
     1261 agtgagaccc attacttttt tgtttttcct tgcttatttt ttattgattc taccgatcag
     1321 cggattaagt tttaattctg atctactgtc aaaaataaaa atccccgctt tcattatgga
     1381 ttttattttt gctaatcgtt ggatcatcgt cagttccttt ttactcgttt atattttcct
     1441 tggctatatt gggattcgac tgatttttgc tttaccggaa atgattctac gggatcgtcc
     1501 ttttcgagca gccattcggg aaagctggtc attgaccaaa tcgcgtcttt tggccatcac
     1561 gggccaattt attgtgattg gcggtacgat tttactcctt tcttctttag gatatatcgt
     1621 tgttattttg gcacaaagta tggttgaaca atttttccca gactatgcat tgatcagcgc
     1681 tgtgtttgct atgacgcttt tacaagggat tttattattc aatatcgtga tgtctaccgt
     1741 agggattttt tatatcattg ttgatttcat ggatgacgaa ggcttcttgc ctgagatccc
     1801 taagtggttt atcccacaag cccccaactt gcgtttctct gcgctgaaaa acactggttt
     1861 gactcttttt gcagtttttt tcggtattgg cgtctgtctt tacaatatgg attatctgac
     1921 ttcagctgtt cagacaaaac cagtgactgt ctctcacaga ggtgtgagta cccaaaatgg
     1981 ggcgcaaaat actttagaag cacttgaaaa aacaagcaga gactatcatc ctgattatgt
     2041 agagatggat gttcaggaaa caaaagatgg tcatttcgta gtgatgcatg atgcaaatct
     2101 tcgtcactta acaggggtaa atggaacacc acaggatctt acattgaaag aattgacaaa
     2161 tcttacagtt actgaaaacg gagtgcaagc ccctgtttgt tcttttgatt cttatttgga
     2221 aaaagcacat aagctaaacc aaaaattact tattgagatc aagacctcta aaaaagattc
     2281 ggatgacctt gtcgaacgat ttgtccataa ataccgcaaa gttatcttag agaaccatca
     2341 tattttgcaa agtttgacgt accaaaccgt ttcagattta aaagaagcag aaccaaactt
     2401 ttatgtgggc tacatcttac ctttcaatat tgttgggccc cctgtgacgc ctgctgattt
     2461 tctgacaatg gaatatagta cgatcaaccg taacttcatt aattctgccc accaagacgg
     2521 aaaagaagta tatgtatgga caatcaacga ttcagatgct atgagtcgca tgatgtttta
     2581 tggtgtggat ggtatcataa ccgatgagat gggactacta aatgaaagtg tgaaacaaac
     2641 agatgaagaa atcacttatt cagataaact gctaaatttt gttttgggag tcggctaatc
     2701 aaaaatcgtt aatgaaaaaa gtctttatac aacaaaaaac gcataacctg ccaccgcagg
     2761 tatatgcgtt ttttgtttga cgctcataat gtgtgcttaa ctttctcttg attccttcat
     2821 cgcacgaaca atagctaaaa tagcaggaat tgcagagatc actgcaagaa taattcccat
     2881 tttccctgaa ctttttcttt ttggcatatc ttctcgctcc cttctgtctt tatttatatt
     2941 ataagggagt tcttgcgaat tctcaaaaat actgtttaag aaaccaattc agcaggtgcg
     3001 ctaatatcac agaattttac gagcatgcga tacttgcttt cattgataag ttgatagtct
     3061 cgttggtcat aactttcaac atacacgaca gccgtgttga tatatgtacg ttcaatacag
     3121 ccgattagtt catgagatac tccgatcggt ttgcatatat aagatcttcc tacttctgct
     3181 tttaccattt cattccctct tttctttatt tttattttgt tttttcttta ttttataata
     3241 acaaattacc ttgtatttga aaacgttttt atccattttt ttatttttta ttttgagtat
     3301 ctttctgctt tttagataac tattttttaa cacgatctta gacgttgtga caaaaacgtt
     3361 tgtttatatt cctatgttgt tcgtgcgttt ttttctttat attgctaagt tatttataaa
     3421 gaggtgagca tatgatttat attcaagcaa tagtatttgt aaccttgatg attgggctac
     3481 ttatcggatt aaaagaaaat agctaaacca tttaagaaaa aataaataag gaaaatgata
     3541 aatgcttttt aattgcatca aaaaacgtac gatgctaaac ttggtataag ttcgaaagtt
     3601 taaaggaaac tttcaagaac taaattacat tacacaggag atgaatttta tgacgtttac
     3661 aaaaacaaat atgcaatacc gcgtagcttt tgatacaact tctaaccgtt ttatggcgat
     3721 tgatgcacaa aacgaaaata acgttgcgtt tggtattaca atcgaacaag cagtccgagc
     3781 attaaacgaa tctagataag gagtgaacca ttccaaatgg cgactgatga gatctcggaa
     3841 aatcaataaa agacgtttgt aacggtaatc cgcgacaaac gtctttttgt attcattaca
     3901 tatatttgga aattgtctct ctttatctct agacctaaac aaaaacacaa gttctaatat
     3961 caaccatctc gttttttatg acaattttgt tagctgtttc gatgataata ttccgttatt
     4021 atctgtataa tatttaatat aatcttaatt gtcaaattaa gttagacaga tcatcaatac
     4081 ttacgtaact caaaaatact tccaaaggtg ttcgataatc cagtgatttt ctaggaatat
     4141 tatttcgttt agatgcg
//
LOCUS       DAFEKH010000121         3878 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.127, whole genome shotgun sequence.
ACCESSION   DAFEKH010000121
VERSION     DAFEKH010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3878)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3878)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3878
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.127"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(718..3867)
                     /locus_tag="LP386_002893"
     CDS             complement(718..3867)
                     /locus_tag="LP386_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HBL1920060.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDSFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKILMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMEPVKKESYLDPTVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSVQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSSTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKANHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
BASE COUNT         1076 a          803 c          637 g         1362 t
ORIGIN      
        1 ggactaatac aggtagtcct cttttttgtt attttgatat tctaaatcat tttttattgg
       61 attattccct tgttcgatat agacccaaat tgatctatca ataattatca aactgagtca
      121 tatagagaca aaaatttcaa aaatgacctg ttaaatggtc atcgaatatc atttaaaatc
      181 aatacgacgg agtcagacac ggagtcaaaa caagcccgct gagagtaaaa aatatataca
      241 gtcccatagg taaagtgcca caggactgta tattttttta tttgagatta cctgaaatga
      301 ttccatttac tttttatctc attttttcct actagttagt atcaaatact ctcctatttt
      361 ctcaataaac tattttgggt tacatggtat ctgaaacagc taaaaccttg tcattacagc
      421 aaaaaatcac tttatctccg tttcatttca gatacatttc acttaagcgg attccaaaaa
      481 aacaaaagaa aaaggaaccc ctagttagcc tatgcttttt attggttcct ctcaaaacac
      541 ggtcatataa caacggggtg gggtaaatga atgaaaaagg tggaggaaac attattcaat
      601 agctgtctta aatacttcgt tataaaatgt gaacaaataa aagacatcta tccctatttt
      661 ctacacttcc actttactac catctttgaa tcgtacaatt ttcttaactc ttctcgttta
      721 cctcaattca ttttcaagtg gaatcagctc atcatctaac attttacgcc atgctcgctt
      781 catttcttgt gggtatttaa atggcttcgc ttctggatgg ttggctttat atccttcgta
      841 atccttactg ttgataattg ctttcatatt aggaattgga tcttcacctg gcatatattg
      901 cagattagaa gcatgtaatt ctttctcaga aacaaaccac tcattggaaa agacatgaat
      961 caaatcatca ctcgcttgtg taaaatagcg acgtttaatg acaaagatat cttcattact
     1021 atctaaagtc cccacatcaa acgcatttaa aatttgtcgg taaacttctt tgactccttc
     1081 tgttttattc aatttagcca aagctttttc aatttcttct cgtgcatctg aactattcgc
     1141 cgcataagtt cctagtaatt gatcaatata agtagaatca atatcataca acttcgtggt
     1201 attttcacta taaaattcga tcgtggaaaa atcttctccc tctttttctg gttcttcctc
     1261 tattaatgaa cccttcacgg tctcgtacac gccaatttgt tcttccaaaa gttgaatttg
     1321 attgttcaag gttgaagatt tcaccatgtc atcattgtaa tcgtcataag tcactaacga
     1381 ttcataagca cgattcaatt cttggaatgc tttgacgtac tcgatacgga tttcaagtgg
     1441 cgtatgttca tcaatggatt ccatggatga aacctctttt aacttaccat atgcttgctt
     1501 gaatcttttt ttggattcct gataacttgg ataaatcaaa cccgattctt cttttgcttc
     1561 tgaatacagt tttgtcgcat cctcgacatt cttctccatt gtggctggct ttcggaaagt
     1621 aacaattagt ccttttgttt tttctggata cgtacggttc gtacgtgaaa aagcttggat
     1681 caatcctgca tactctagat tacgatccac aaatagggtt tgaatcgtag gtgcgtcaaa
     1741 acctgtcaat agacgatcca ctacgatcac taaatcaatt tgtttcccaa attgtttgaa
     1801 ttccgctctt tttcgtgcca aacgattatt gatgtctccg ttataacgct caatgtctgc
     1861 taatgaccag gaagtatcat aatactgatt atattcctca ataatttttt gcatttcttc
     1921 ttgttggaca cttgaatctc ggctgttttc ttctaatgaa taggtaatag cgattcgtgg
     1981 aaaatcagga tcctccatcg ttcttccttc acgaatgggc tgattaggaa actcttttgt
     2041 taaccagtca ggttctttcg tcatttcttt gatcgctcga taatactttt tggccatgtc
     2101 aatggaactc gtggttaaga tcgcagactt cgttggacgg ccatttcgaa aatcaaattt
     2161 tgtataggca ttgtctggac ggaacatttt atgaatgact ttttggatat gttcatctgc
     2221 ttcaaaaaca gtagggtcca aataactttc ttttttgaca ggctccattt gatcaatcat
     2281 acgattgatc tgttccggtg aatactctgc atatgtttct acttctttta atttccgata
     2341 gattttattc tctaatgaag tcggctccac ggtgttttca tgctctactt gaaatcctaa
     2401 aaccgagcca tcttctaatg cattcttgat ggtataggta tgcaagacct ctccatactg
     2461 atcatgggtc gtacgtgcca attgcccttt ggcttgtttc cgattctcag ggaaaatcgg
     2521 tgtacctgta aagccaaacc aagtggattt cggaaacatt tttttgattt cttccatatt
     2581 ttcagcactt aacgctcgat gacactcatc tactacaaac acgatatgtt gccccattaa
     2641 tttttggaag cgattggttc cttttttctc ttcttgtttt tttgcatatt tcaacgccgc
     2701 atctagcttt tgacgggttg taataatcac aacatttgca ttggcatctg ccaacagagt
     2761 ttcacttaac tctttggcac ttcctgttcc cacgatcaag ctattcgctt tggcgttccc
     2821 ggaagaaatc ccagtattaa attccgaagc aaatttcgta aactctgtgg tggtttgatt
     2881 atctaaatct ttgcggtcca ctaacatgat cgtccgatcg atccccgatt ttcgtgctaa
     2941 aagcttagta gatacaaaac tagtcaacgt ttttcctgaa ccagtcgcat gccacacata
     3001 tcctgattga tgtttatttg cagcaataaa caaggcttga atcgcatgta cttgataagg
     3061 atgtaacacc atgaggattt tattgtcttg atcttcactg acaatcgtat aatccgcaat
     3121 caagcgatga gcatccggga tatttagcac ttgtttgcaa aactcatata agttttctac
     3181 ctttttatta tctttcgttc gccaactaaa taaaaactta ggatgcaaat cctttggtaa
     3241 ggcatttgca aaataccgag tggtttgttc attggaaacc acaaacaact gtaaggtcga
     3301 aaagatattg ttccgaaaca taccttcttc tgcatatttt ttgatttggt taaacgcctg
     3361 ataaaaacta tcttttgcgg ttacttgttt cagctcgatt tggacaatcg gtaatccatt
     3421 gatcagtaag gtgacgtcaa aacgtcgatc ccgtgcttct atgttacttc cacgttttgc
     3481 aatttgatgg accacttcat aggtagagat tcctccacca atgtcttgat tagaataaag
     3541 aatgagcgag acagaaccca gttgcggatc ttcccgttca atcgtgatcc gagccattcc
     3601 attttcacct tttaaccatt tcgcagcatc aaagggggtt ttcgttcgta gtaacaattc
     3661 tgttttgatc gtttcaaatt ctttatcggt caaaggaaaa tcattcagtt ctgcttgatt
     3721 atttgagatg attttttggc gtaaattgac ccaaagatct tcttctgatt ttagatcggg
     3781 acgatacgtc cactgattat gcccttcccc caatacacgg atcaactgtt cttcgacttc
     3841 cgcttcctca cggtgactaa ttttcattta tcttccct
//
LOCUS       DAFEKH010000122         3810 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.129, whole genome shotgun sequence.
ACCESSION   DAFEKH010000122
VERSION     DAFEKH010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3810)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3810)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3810
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.129"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            97..2196
                     /locus_tag="LP386_002894"
     CDS             97..2196
                     /locus_tag="LP386_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBL1920061.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            2392..3255
                     /locus_tag="LP386_002895"
     CDS             2392..3255
                     /locus_tag="LP386_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBL1920062.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            3360..>3810
                     /locus_tag="LP386_002896"
     CDS             3360..>3810
                     /locus_tag="LP386_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBL1920063.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEK"
BASE COUNT         1522 a          636 c          772 g          880 t
ORIGIN      
        1 ttaagtaaat cctaaaaata agctattggc gtgacgtata gaatatgata gattaaatgg
       61 tagcgtaaac ctagtaaagg agccgatcgc taagtgatga aaaaatgtcc aaattgcgga
      121 tcgaaaaaaa tggagcagaa tactatctgt ccagactgcg gtcatcaaat aactgcagaa
      181 gatcagcaaa taaaagaatc aattgaagaa acaaatacag atgcagctat gcaggataaa
      241 tcaactgaag atgcagtctt tcctgataca gaattaaacg atccaatcga atggtcggaa
      301 ttgaaagatt tacctctaga atctgtaatg gaattattcg aaaaagcaga accagaagac
      361 gaagaaccac ctgctcacga tcaagtaact aatatagaga aaaatgaaca gaagaaagca
      421 actgttcatg agacttcgga agaatcagga aagaatcaag aagaaacgct tgaatcaaaa
      481 caaaaaagaa gagtagctga actgaaagaa atcgtcgata atgaggaaga aaattcgata
      541 ctatccgctt atatcaaagc acatcgtgaa gatacaaaag aagagcacgc gaaagagctg
      601 ctcaaaatga tcagtgaaaa aattgcacag gaaaacaaag tagagccaga aaaggaacaa
      661 gaaactgaaa aagactctga tagagaaaac gccacaggta aagaaacagt aaaaataaaa
      721 gacgtaaaaa cggatatcac agaaaaaact gaagtattta ctgaaaaaca attagaaaag
      781 gaaaaaacga ataaactgcc ggaagcagag aaaaaagaaa tactcgaaaa cacagacaaa
      841 aagtcaacag agcccgatga aataaatagt gaatccgatg ctgaaaatca atctgtaagc
      901 aaagagggta ctgatcttga agcaaaaata gaaaaagaag agaaccagcc taagctgttt
      961 gaagcagaag cgaaatcaat aacaatcgtg ccagatactg aaaaaacaca tcaagaatca
     1021 aacttagaaa aaacagatcc agataaagcg caaaagaaaa aatcaaaaaa agtaccttat
     1081 ctcgttttag cagcagtact tctactcggt ggaggaagct gggcttatta tgaccatcat
     1141 caaaaagtag aagccgaagt agcagcagaa gcaaaaagac agcaacaaat ggaagaactt
     1201 catgagaaac ttgctgcctt ttatacagat gatcaccatc aatttattcg tgcagatatg
     1261 attcatcaag atttatcaaa actaaaaaat gatttatcca gtcttaagaa tgaaaaagga
     1321 tattcagagt tagaaacaac ttaccaagat atccaatcta agatccgaga tatccaaaaa
     1381 gtgaatgagt ggttcatagc acctgccatc gtcgatgatc atctagcaga tgacatcaag
     1441 ttgaaagcag ataaagagat ccaagcaatc gaaacggata acacagattt tggaaaattg
     1501 attcaacaag cacaaacaga agctaaaaat caatatgctg aattgcaaac agctaaagaa
     1561 aaaacagcta tagtctttaa agacggaaaa gtagtggatt cagcaacacg cgaccaatac
     1621 aagacggcaa aagaagcagt agaaaaagtg aaaaatacag atctatctgc tcagttgaat
     1681 gaacaattga aacaagtaga taagatgctc actgataaag agaaaaaaga agaagaggaa
     1741 aagaaaaaag cagaagaagc gaaaaaagca gctgaagaac aagcaaaaca agccgctcaa
     1801 gcagcagctg cagctcaagc cgctcaacaa gctgcggtcg cacaagcagc acagcaagaa
     1861 gcggcatcct cgaccccttc ctcttcaaac tcagcgaatc agccaatcaa atctgccaga
     1921 gcaagtgata ttgccgatgc atctaatcca gcatggacgt gggcaccagg tgtccaaagc
     1981 aaagtgattg ctacatgtat ccaacgtgga tatatcgttg aaggaggtta cagattagaa
     2041 aaagccagaa tcgaaaatgg ggaaggctat tataatctat atgccacttc aacaaaatct
     2101 gcattgatga aaggcattgg agaaagtgct ttgccatttt acatcgtaac catcaactgt
     2161 aaaactggat ggttcggagg aaatgggagc aattaatttt aggcaaatga aagaggctgt
     2221 gagcctgccg tttaacaccg tttattcgaa aaaggggagt atgacacaac tgttgtcata
     2281 ctcctttttt cacctttcca aaccaaggct cagctattca agtagataac attatgttat
     2341 gatagcaaag aaatgtatta agaaaacctt tcactataga gggagaaaaa aatgaacgat
     2401 ttattagcaa ctatatttac aggtattatt attgatgaaa atgaaaaaaa ctactttgtc
     2461 caaaaaaacg gacaaacctt tggcttaagc aaatcagaag gtgaacacaa aatcggtgaa
     2521 gcagttgaag gattcggtta ccaaaatcaa aaacatgaaa atcggatcac tacacaaatt
     2581 cctaaaagcc gtatcggtca ttacgctttt ggaatcgtta ctgctacacg aaaagattta
     2641 ggtgcgtttg tcgatatcgg tcttccagat aaagactttg tcgtatctct tgatgaattg
     2701 ccgacaatga cagagctatg gcctaaaaaa ggggatcgct tgatgatttc ccttagagtt
     2761 gatgcaaaag accgtatttg gggcagttta gcagatgaaa aaatattcaa atctttaagc
     2821 aaatatggaa cagaagaaat gaaaaacaaa gatgtgatag gaacagcata ccgcttgaaa
     2881 ttaacaggta cgtacgtttt aacggaagat ttctatcttg ggtttatcca tccttctgaa
     2941 cgatataatg aacctcgtct aggcgagcag ataaaaggtc gagtgattgg tgtccgacca
     3001 gacggtgtac tgaatctttc attgaagcca agagcatatg aagctatatc agatgatgca
     3061 caaatgattt taaccatttt agaacgttct gcagatcagc aaatcaactt tacagataaa
     3121 tcggatccag aagaaatcat gaaagctttt ggtatcagca aaggagcatt taagcgcgca
     3181 ttaggtaatc ttttgaaaca aggattgatt acacaagaaa acggtgtgac aaaactagtc
     3241 aaaaaatcta attgagaatc ccttgcatgt ttttcttaac tagcttataa taattttaat
     3301 taacatagtg ttatatcttt ttttatttgt aattattata aattgttggg gttgagtaaa
     3361 tggtcatgaa tgctatttcg gcgatgaaaa aaacaaaaca gcagctacat gaagcggggt
     3421 ttaagctgac accgcaaaga gaagctactc tgcttgtgct tttggaaaat gagaaagagc
     3481 atttatctgc agaagaaatc ttctttttag tgaaaaaaaa gagtccggaa attggacttg
     3541 ctactgttta tcgaaccctt gaaatcttga cagaattgaa aattgtcgat aaagtaagtt
     3601 ttaatgatgg attagcccgt tatgatttga gaaaagaagg cgccaaacat ttccatcatc
     3661 atttactatg cttgaactgc ggcacgatcg aggaagtaga agaggatctt ttacttgaag
     3721 tggagcaagt agtagaagaa cgttatcatt ttttagtaaa agatcatcgg ctaacgttcc
     3781 atggaatctg tcaggaatgc tatgaaaaag
//
LOCUS       DAFEKH010000123         3525 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.131, whole genome shotgun sequence.
ACCESSION   DAFEKH010000123
VERSION     DAFEKH010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3525
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.131"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..186
                     /locus_tag="LP386_002897"
     CDS             <1..186
                     /locus_tag="LP386_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1920064.1"
                     /translation="ISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGV
                     SPKQYQLGLVDNFNNIS"
     gene            203..637
                     /locus_tag="LP386_002898"
     CDS             203..637
                     /locus_tag="LP386_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920065.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            1254..>3525
                     /gene="esp"
                     /locus_tag="LP386_002899"
     CDS             1254..>3525
                     /gene="esp"
                     /locus_tag="LP386_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HBL1920066.1"
                     /translation="MISKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLVGVGLVLGTT
                     ELVKAQDEISPSTPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTDNWEIRLQLDERLAKYVENIQVDSKKVAGISYRRTF
                     VRINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKNLDEIFQEIGED
                     NLKSDRLMYRIYLVSHQDNDKIVPGIESTGYFITDQDNFYNKLDVSENNPDQFKHGSV
                     STKYEKPNVQTKDGSGSTGANGAIILDHKLTKEKNFSYSVSATGTPWYANYKIDERLV
                     PYVAGIQMHMVQADRVVYDVSFESGTKVADLAIERREGHENYGVGSITNNDLTKLIDF
                     SNASPRPVVIRYVLQLTEPLDEILAEMKTAAQVEGNEPFGEDFIFDSWLSDTNKKLIQ
                     NTYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAG
                     TGHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSNKLIAKDELKVQIVS
                     PGFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTS
                     NVADSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTIQSGKPTFD
                     KPDVPLANDAFSILDVYNKDFGNASVDANTGIVTFTPAKGVGETEPITGTIPIKIVYQ
                     DGSVGTTDLAVTVSKDI"
BASE COUNT         1272 a          493 c          683 g         1077 t
ORIGIN      
        1 atctctaagc gaaaaatttc tacggctaaa ataatgttga aatcaaacca tactatcagt
       61 gaagtttctt taggtttagg attttcagat tcttcacact tttcgagagt attcaaaaag
      121 tacgcaggtg tatctcctaa gcaatatcaa ttaggtttag tggacaattt caacaacatt
      181 agctgagagg ttttatttta ttatgagact atatcattta cgtagtttgg aggagttgag
      241 gaaattggat tttaacaaaa aatttttttg ggaaatttct gatttgagtt gtttcgtaga
      301 atctgagcgt ctaagtaatg gtaataatag tgtgttaaat gaatatgaca aagtagtaat
      361 taataaagta aaaagtttat gtgaagaagc tagagaatct atcagtcata ttaatggtag
      421 caattttaag caaacattat ttaatctgat taagctagat gctaaaatat caagttattt
      481 attcttttta atacatgatg aatttatgga ttatcaaaaa ttggatcagt taattgaaag
      541 agaaagctgg gaagattatt acgtgggtct aactttttca gaaaagttaa acaactacaa
      601 gttaatagat tataagtatt tgagtgaaag caattaatta ttcatgtaga gtactagaca
      661 ctttaaatat ggacaattca attataaaga aaaagaatca ataatttaat gaggctgtga
      721 caaatgtcat tttttgtttc gctaaaaacg agtgaaaaaa tgttgataac tccaatcatt
      781 cgtttaagat tctaggaatc attcagaaat gctgtgaaac cgatacttta taattataaa
      841 gaaggtgatt tcaaattccg aagaaggaat ttgaagtcac ctttttactt atgtcacagt
      901 ctcattcagt aatgcgggat aaggctcctt attccgctat ttgaatactc tgaagtttaa
      961 tctaagaaag agtaatattt tgaaaacatg cttcatcgca tagaaatgaa cttaatttca
     1021 gaaagaatac atacatatct ttttatatgt tttcagctgc tgaatggtta aaaagcacaa
     1081 atatccgaaa aaaacatgaa gaaatgtact ttttttgttg taatgtgcat gaaattcttt
     1141 aagtaaatta gttaacataa gtttaataag attcctattc tgtgaataat acgtatcaga
     1201 tttatctttt attcttacta ggaaaataac tattaaggga gttgatttga ataatgatta
     1261 gcaagaataa taagagagta tttctagaaa aaacaaagaa acgagtattg aagtacagta
     1321 tcaaaaaatt aagtgttggg gttgcatctg ttttggttgg tgttggtctt gtcttgggaa
     1381 caactgaact agttaaagca caagatgaaa tttctccaag caccccactt gaaacagcga
     1441 taagctccgt acaagtaggt gacaaagtag cttcggggaa tacttttcag gagaatcctg
     1501 gttatacgaa aaattataac ttttcggatt tacaatttag tcctcaagaa ctaactggag
     1561 acacactaaa aggcaataca attggatttg aagtttacgg aaaacataat attgctgctt
     1621 ctaccgataa ttgggaaatc cgcctccaat tggatgagcg attagccaag tacgttgaaa
     1681 acattcaagt agattctaaa aaggttgcgg ggattagtta cagaagaact tttgtccgaa
     1741 tcaatgattc attaggtaga cccacgaaca tttggaaagt taattatatt cgtgcaagcg
     1801 atggattatt tgctggggca gaaacaactg atacacaaac tgctcctaac ggggtaatta
     1861 catttgaaaa gaatctagat gagatttttc aagaaattgg tgaagataac cttaagagtg
     1921 atcgtttgat gtatcgaatc tatctggtaa gtcatcaaga caatgataaa attgtacctg
     1981 gtatagaaag tactggttac tttataacag atcaagataa tttctataat aagttagacg
     2041 tatctgaaaa taatcctgat caatttaaac acggatcggt aagtaccaaa tacgagaaac
     2101 caaatgttca aacgaaagat ggatcggggt ctactggtgc taatggcgct ataatcttgg
     2161 atcataagtt aacaaaagag aaaaatttct cttactcggt ttctgcaacg ggaacgcctt
     2221 ggtatgctaa ctacaaaatt gatgaacgtt tagttccgta tgtagcgggt atacaaatgc
     2281 atatggttca ggctgatcga gtagtatatg acgtttcatt tgaatcagga acaaaagtag
     2341 ctgatttagc aatcgagcga cgggaaggtc atgaaaatta tggtgtaggt tcaataacta
     2401 ataatgattt gactaaactt atcgattttt ctaatgcaag tccacgtcca gttgttattc
     2461 gttatgttct tcaattgact gaaccattag atgaaatttt agcagaaatg aaaacagctg
     2521 cacaagttga aggaaatgaa ccgtttggtg aagacttcat ctttgattct tggttgtcgg
     2581 atacgaataa aaaattaatc cagaacactt atggaacagg ttattattat ttacaagata
     2641 ttgatggtga tggaaaccct gacgataaag aagagagtgg agacacgaat ccatatatcg
     2701 ggaaacctga attagaagaa gtatatgatg ttgatacaac agttaagggg aaagtattca
     2761 tccacgagtt agcgggaaca ggtcacaaag ctcaacttgt tgataaagaa ggtactgtat
     2821 tagcagaaaa aactattgct ccaaatgaaa aagatggagc tccaatttcg gatactgtag
     2881 aatttgaatt tacgggtgtg gattcaaata aattaattgc gaaagatgaa ttaaaagttc
     2941 aaatcgtttc tccaggtttt gataaaccag aagaaggttc aaccgttatc aaggaatcac
     3001 caaaagcggt tgataaacaa accgtggtag ttggatttaa accagatgct aaagaatcaa
     3061 ttcggaataa taaaaactta cctgaagatg cagagtattc atggaaaaca gagcctgata
     3121 cttctaacgt tgctgatagt acgaaaggta ttgtaactgt taaaatcgga aatcgaactt
     3181 ttgacgtaga tgtagagttt gctgtaaaag cttctcaagc tatggaaaat gatgcaacat
     3241 acgtacctat aacaacaacc ccagaaacga caattcaaag tggtaaacct acatttgata
     3301 aaccagatgt tcctctagct aacgatgcct tttcaatttt agatgtttat aataaggact
     3361 tcggcaatgc aagtgttgac gcaaatactg gtattgttac attcactcca gccaaagggg
     3421 taggagaaac ggaacctatt actggaacaa ttcctatcaa aattgtttac caagatggtt
     3481 ctgtaggtac gaccgatttg gcagtaactg taagtaaaga tattt
//
LOCUS       DAFEKH010000124         3369 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.132, whole genome shotgun sequence.
ACCESSION   DAFEKH010000124
VERSION     DAFEKH010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3369)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3369)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3369
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.132"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(161..2158)
                     /gene="tkt"
                     /locus_tag="LP386_002900"
     CDS             complement(161..2158)
                     /gene="tkt"
                     /locus_tag="LP386_002900"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBL1920067.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2260..2511)
                     /locus_tag="LP386_002901"
     CDS             complement(2260..2511)
                     /locus_tag="LP386_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HBL1920068.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2658..3281
                     /gene="lexA"
                     /locus_tag="LP386_002902"
     CDS             2658..3281
                     /gene="lexA"
                     /locus_tag="LP386_002902"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HBL1920069.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
BASE COUNT          920 a          739 c          626 g         1084 t
ORIGIN      
        1 tcaagaaaca caaactaatc cgaagaattc tttgttttgt catttaaatg taacatagcc
       61 gaaaacgaaa agtaatattg atttattctt ctaacacata aagaacagct gtctccaact
      121 tgcagacagc tgttcttatc agtcaaacaa ttgcttggat ctatgatagt tgattgtacg
      181 tattcacgac attttctact gtaaatccaa attcttctaa aattttagtg ccaggggcag
      241 atgcaccgaa atgatcgatt gtaatcgttg cgccctctgt tcctacgtag cgttcccatc
      301 caaatgatgc agcagcttcg atagccacac gtttcttcac tgatttagga agtacacttt
      361 ctttatattc agaagattgt ttttcaaaga ggtcaaagct tggcatagaa acaacagaaa
      421 catctttgcc tttttcagcc aattcttttt gagctttcac agccaaatca acttcagaac
      481 ctgttgcaat caaaatacct tctggtgttt ctccttgtga tggagaaaga acatacgcgc
      541 cttttttcac catttcatct gctacttctt ttgtagaagg caatactgga aggttttgac
      601 gactcaatac aaggatagta ggcgcatctg ttgtctccat cgctactttc caagcagcac
      661 gtgtttcatt tccgtctgcc ggacgaatca cttgaacacc aggcatgcag cgaacagatg
      721 ctagttgttc aatcggttcg tgcgttggtc cgtcttctcc gacagcaacc gagtcatgtg
      781 ttaagacgta aacaacagga gtatgttgga ttgctgctaa acgaactgct ggtcttagat
      841 aatcgacaaa gacaaagaat gttccaccgt agatacgagt tccgccatga agttggatac
      901 cattcatagc cgaagccatt gcaaattcgc ggacaccgaa ccagatgttg cgtccttcat
      961 aatgttcagg agtgaaatct ttatctgcag ccaccattgt attattggaa cctgacaagt
     1021 ccgctgaacc accccagaag cttggtatag ctttcgataa ttcttggatg acttctttac
     1081 ttgaaacacg gcttgcttga ctgcttccaa cttcataagt tggcaattct gcatcccagt
     1141 tttctggtag tttgccatca aaagcatctt caaattgttg tgctaattca ggataagctt
     1201 ttttataatt ggcaaacatt tcattccatg catcttcagc tttttgtcct tcttctatca
     1261 tcgtttgatg gaagcgggca gctacttctt ctggaacagt gaaatctgga tactcccaac
     1321 cataaacttc tttagccatc ttgatgccat cttcaccaag aggagcacca tgaacagcag
     1381 atgttccttc tttaggagca ccatagccga tgactgtttt tacttcgatc aatgttggtt
     1441 tgtctgtttc agcttttgct tcttcaatcg ctttagagat tgcttctagg tcatttccgt
     1501 ctttcactaa gatatgttgc cagccatatg cttcatagcg agcaccaacg ttttctgtga
     1561 aagcttttga agttggaccg tctagtgaaa tatcgtttga atcgtataaa acgatcaatt
     1621 tccctagttt catatgacct gccatcgaac ttgcttcttg agatacccct tccatcaagt
     1681 ctccgtcacc gcatattgca tacgtatagt gatccatcac attaaagttt tctttgttat
     1741 acgttgctgc aaggtgcgct tctgccattg ccataccgac agccattgca atcccttgtc
     1801 ctaatggccc tgtagtggct tctacaccat ctgtatgatg tacttcagga tgtcctggtg
     1861 ttttagaatc ccattgacgg aattgtttca aatcatcgat tgtcacttga tagccagcta
     1921 aatgaagcaa gctatacaac attgctgacc catgtcctgc cgaaagaacg aaacggtcgc
     1981 ggtcagccca gttttttgat gtcgttggat ttactttcag gtgttttgtc cataacgcat
     2041 atgccatagg tgctgcgccc atcggcaatc caggatgtcc tgagtttgct ttttggactg
     2101 cttcaatact taatgtacga attgtgttaa cgccaagttg gtcaattttg tcaaacaaaa
     2161 taacccctcc tattaattta ggtttttttt acctttattt cttacacttt cattctataa
     2221 gatgtcacac gaaaaagcaa tctttttcag tattttttac taaaagttgt catttcggtt
     2281 gtgtaagcct tttttctttt ggatttcttt taatttttcc ggggtcacgt cattgccctc
     2341 aggatcgacg actttcattc cttcgatatg atgacgcata ccggaacgaa aagcttccaa
     2401 atactctttg cgcaagttga tttgttcttg ttcttcggct tttgagagac cattttcctt
     2461 ctttttacgt gcaagttcat tgatccgctc tattttttca ggtgacagca tgctcagccc
     2521 tccttttact ctccttcata ttatataaaa actgaaaaaa aaacaactag ataaactaaa
     2581 taaaatacga acattcgttt gatttagcgc tttttatatg gtactattta tttatcaagt
     2641 gaaagaaggt gtaccttgtg gcccgacaaa ctgaatcaag acaaatcgaa gtcttacgat
     2701 atatccatga acaagtaacc caaaaaggat acccgccgac tgtccgtgaa atcggggaag
     2761 ctgttcagct ttcttctact tctactgttc acggtcatct tgcacggctt gaaaaaaaag
     2821 ggtttatcca aagagatccg acgaaacctc gtgcaatcga gttgacaaaa caaggtttag
     2881 aaaagattgg gattcgtcca acaactattc cagtacttgg cgtcgtaaca gctggagaac
     2941 ccattttagc agtagaggat gcttcagact tctttccaat ccctcctaat ctttcttccg
     3001 aagaaggcag tctctttatg ctgacaattc gtggagatag tatgatcaat gctgggatat
     3061 tggatggtga caacgtgatc gttcggaagc aagaaactgc tcaaaatggc gatattgtca
     3121 ttgcaatgac tgccgaggac gaagcgactt gcaaacgatt ctataaagaa aaaaactttt
     3181 tccgtctgca gcctgaaaac gacttgctcg aaccaatcat cttagatcaa gtatctatat
     3241 taggacgagt agtaggactt tatcgtagtc atatctatta attgctacta attaaaagaa
     3301 aactttttaa aaagagtttg agacgttggt ctcaaactct tttttcgccc gggttcttct
     3361 tctttcaaa
//
LOCUS       DAFEKH010000125         3294 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.133, whole genome shotgun sequence.
ACCESSION   DAFEKH010000125
VERSION     DAFEKH010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.133"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            39..590
                     /locus_tag="LP386_002903"
     CDS             39..590
                     /locus_tag="LP386_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF334 domain-containing protein"
                     /protein_id="HBL1920070.1"
                     /translation="MKRLEASTSNFNNKLDVFEEKTKHARLNFETTAKHYIKRLDEDN
                     LKLDFQQAIQDELSDTKDEIREVTKQAREETKEYKEILESKIKDHNKVVDKSNTALKV
                     MTKGVTNIFFVLIIFVLVMLVTGPIGHFFGIEHLYSFINGFIDDHESAWRYLMLILYA
                     VPYVFFAIILWLIALFFRVFNDL"
     gene            1266..1520
                     /locus_tag="LP386_002904"
                     /pseudo
     CDS             1266..1520
                     /locus_tag="LP386_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405927.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
     gene            1590..2102
                     /locus_tag="LP386_002905"
     CDS             1590..2102
                     /locus_tag="LP386_002905"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1920071.1"
                     /translation="MTNKNNERYSTELKATAIKKMMPPENRGIRQLSQTLGIPEATLC
                     SWRKKARIQGNTTPGTKKNVEKWSSEDKFLIVMESFSMNQVELAEYCRKKGLFKEQIE
                     AWKKTCLSANEQEENRTRELATELKEEKKQARQLEKELRHKEKALAEAAALLLLRKKA
                     HAIWGDQEEE"
     gene            2099..3136
                     /locus_tag="LP386_002906"
     CDS             2099..3136
                     /locus_tag="LP386_002906"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBL1920072.1"
                     /translation="MISSSDRKQAVELIQEANRNGARLTYACNELNISVRTYERWTRE
                     GTIAHDQRPLAKRPVPKNKLTDQEREKIIETVSKKEFMNLPPSQIVPKLADCSIYIAS
                     ESSFYRVLREKNMQHHRGRSQVSQKRIPPSHLATKPNEVWTWDITWLKGPIKGLFYRL
                     YLIIDLFSRKMVGWEIWESEEARHAEKLIKQTVLKERIQGQPLVLHSDNGSPMKAATF
                     QVLLEKLGIQSSYSRPRVSNDNPYSEAAFRTLKYRPEYPNNGFKTIDDARKWTKEFVD
                     WYNDSHLHSGIQFVSPAACHEGRHLAILEKRKQVYEDAKKRHPERWSKGVRNWTPHQS
                     VALNPLKETES"
BASE COUNT         1214 a          555 c          654 g          871 t
ORIGIN      
        1 agagcgagca agacaggaac gagagaacaa acatactcat gaaaagacta gaggcttcga
       61 cctcgaactt taataataag ttagatgttt ttgaagaaaa gactaagcat gcaagattaa
      121 actttgaaac aactgcaaag cactatatta aacgacttga tgaagataat ttgaaattag
      181 attttcaaca agctattcaa gatgaattaa gcgatactaa agacgaaata cgtgaagtga
      241 cgaaacaagc gagagaagaa acaaaagagt ataaagaaat cttagaaagt aaaataaaag
      301 accataacaa agtggttgat aaatcgaata cagcgctaaa agtgatgaca aaaggcgtta
      361 caaatatatt ttttgtgcta attatttttg tacttgtaat gcttgtgaca ggtccgatag
      421 gtcatttctt tggtattgaa catttatata gctttattaa tggttttatt gatgaccacg
      481 aaagtgcatg gcgatatttg atgttgatac tttatgcagt accctatgta ttcttcgcta
      541 tcattctgtg gctcatagca ttgtttttta gagtatttaa tgacctttag gtagatttat
      601 atataaaaag ggctaaatac gcaaaatacc cccttaaaat gcaaaataaa tgcaaataag
      661 ggggtaactc cttatgaaaa aacaactaat agtattataa cacgttttta tgccgagaaa
      721 acttattggt tggaatgggc tatgtgttag ctaacttgtt agcgagttgg ttggacttga
      781 attgggatta atcccaagaa agtaccaact caacaacaca taaagccctg taggttccga
      841 ccaataagga aattggaata aagcaacgaa aggagttgag taaaatgagt gagaaaacga
      901 agaaaatcat tcgagtatca ttagcttttt cacaagtagt agtgcaatca ttgatagttt
      961 attatactta ccagcaatat aaattatcta aagagaatta agttttgatt atgtaataag
     1021 ttttggtact aaaaaagact tgatctaatt agaccaagtc ttttgttagt gttatattaa
     1081 taacaaaata aaaataagaa gtcgctcact ccccgaccaa agtttgtgag caaaataaac
     1141 agtcgatgtt tgtttcttaa ttgtatatct tgatattaaa cgatttaaga ttattcttca
     1201 agatatatat tcgcaaatgt aattggaaaa gcgacttctt aaacaaaatt aaggagtcgc
     1261 tttttatggc aaaaataacg aaaaatgagc aagaaaattt ggtggaaaat tacacaaaaa
     1321 aaccggcgta ctctaatagc cggttagacg cacatttcgt gtgcacttct aatccgaaat
     1381 tgagctttga cgctatgacg atagtcggaa accttaataa aaacagcgct aaaaagctat
     1441 ccgattttat gagtttagat ccacaaatta gactttggga tatacttcaa acaaaattta
     1501 aagctaaagc actacaagac cccctatgtt aggctagttg tcgtatagga taataagtta
     1561 taataaagac tatacggagg atgattacca tgacaaataa aaacaatgaa cgttactcta
     1621 ccgaactgaa agcgacagcc atcaagaaaa tgatgccacc cgaaaatagg gggattcgcc
     1681 aattaagtca aactttgggc attccagaag cgactctttg ttcttggcgt aaaaaagcta
     1741 gaattcaagg gaatactaca cccggaacga aaaaaaatgt cgaaaaatgg tcaagtgaag
     1801 ataaattttt aattgtgatg gaatcattct caatgaacca agtagaactt gcggaatatt
     1861 gccgaaagaa gggcttattt aaagaacaaa ttgaggcttg gaagaaaacg tgcttatctg
     1921 cgaatgaaca ggaagaaaat cgaacgagag aacttgcaac tgaactaaaa gaagagaaaa
     1981 aacaagcgcg tcaattagag aaagaattac gtcataagga aaaagcatta gcggaagccg
     2041 ctgctctctt attactaaga aaaaaagcac acgcgatttg gggggaccaa gaggaagaat
     2101 gatttcatct tcagatcgca aacaagctgt tgaacttatt caagaagcca atcgcaatgg
     2161 ggcccgtctc acctatgcct gtaatgagct gaatattagc gttcgaacct acgaacgatg
     2221 gacgcgtgaa ggtacgatag cgcatgatca acgccctttg gcgaaacgtc ctgtacccaa
     2281 aaataaactg acggatcaag aacgcgaaaa aataatagaa accgtttcaa aaaaagaatt
     2341 tatgaatttg ccacctagcc aaattgtacc aaaacttgcg gattgctcga tttatattgc
     2401 atcagagtct agcttctatc gtgtattgcg agaaaaaaat atgcaacatc accgtggccg
     2461 aagtcaagtt tcacaaaaac gcataccgcc aagtcacctt gcgacgaagc caaatgaagt
     2521 ttggacttgg gatattactt ggctaaaagg tccaataaaa ggactctttt accggttata
     2581 tctcatcatt gatttattta gccgtaaaat ggtaggctgg gagatttggg aatcagaaga
     2641 agctcgtcat gccgaaaaac ttattaaaca gacggtgctt aaggaacgta tccaaggaca
     2701 gccgttggtt ttacactccg ataatggcag ccctatgaaa gccgcgactt ttcaagtctt
     2761 actcgaaaaa ttaggaattc aaagttctta ttcaagacca cgagtgagta atgacaatcc
     2821 ttattcggaa gcggctttcc gaacgttaaa atatcgacca gaatatccca ataacggctt
     2881 taaaacaata gatgatgctc gaaaatggac gaaagagttt gtcgattggt ataacgattc
     2941 tcatttgcat agtgggattc aatttgtgtc tcctgcagcg tgtcatgaag gacgacatct
     3001 cgctatttta gagaaacgaa agcaggttta cgaggacgct aaaaagcgcc atcctgaacg
     3061 ctggtcaaaa ggtgttcgaa attggactcc acatcaatcg gtggcgttga atcctttaaa
     3121 agaaacagaa agttaacagg agcataatct ttcaagatta tcaaataacc ctcgtcaccc
     3181 aataggggaa aaagttattc ttcccctatt ggataacgag gccaaccgac catagggagg
     3241 ttctgctttt tgataggtgg aaaataaaaa tacgacaact atattgacaa acac
//
LOCUS       DAFEKH010000126         3218 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.134, whole genome shotgun sequence.
ACCESSION   DAFEKH010000126
VERSION     DAFEKH010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3218)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3218)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3218
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.134"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            50..1438
                     /locus_tag="LP386_002907"
     CDS             50..1438
                     /locus_tag="LP386_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="HBL1920073.1"
                     /translation="MYKERDDLNYTLIINKDGNYSWRPLVLLHPILYVDLVNCLTKED
                     HWEELKKRFSEFKKDKNINCYSIPVEASKGSKRTDLGETILNWWEYFEQKSLAQNIKY
                     QYCMFTDIADCYPSIYTHSITWAMYGKEKVKNDENKCSGSLGDKIDKKISGMQHNQTN
                     GIPQGSVLMDFVAEIVLGYVDLRLSKELKKLENLKDYKVLRYRDDYRIFSNNRNDLEQ
                     IMKVLSEVLYDLNFKLNSSKTKLSDDIIIDSIKKDKLYWEEIKASIRMNATNLDGDRE
                     IRYSINLQKHLLEIKKLADKHPNSGQLKKALSEFNKERIIKITSKPNDLLPLIGILVD
                     IMINNPGSLPQCVLIIGQLLNFENESKAREIVEMIINKYALKPNTEFMMIWFQRLTTI
                     FGEMFDSVLSSEFVSKIKDPVSNQMFSVDWLNEDAKKSFYEGTIKDEEKYIKMSKKIY
                     ITEFDDFNDYPF"
     gene            1776..>3218
                     /locus_tag="LP386_002908"
     CDS             1776..>3218
                     /locus_tag="LP386_002908"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HBL1920074.1"
                     /translation="MTEQIEKNSKSLYQALWNSADILRSKMDANEYKSYLLGLVFYKY
                     LSDNMLRYVSVLLEEETDDLNKAQDLYVEAFKDADIKDDLLYELKDEFSYTIAPALTF
                     TAQVAAIHDGSFQLEDLVQGFRDIEQSSENFENLFEDIDLYSKKLGSTPQKQNKTIAD
                     VMKELEGLNMAGHAGDVLGDAYEYLIGQFASESGKKAGEFYTPQPVAKLMTQIVLQGK
                     EDKKGFSVYDATMGSGSLLLNAKKYSHQPGTISYFGQELNTSTYNLARMNMILHGVPI
                     ANQHLHNADTLDQDWPTEEPTNFDGVLMNPPYSAKWSADKGFLDDPRFSAYGVLAPKS
                     KADFAFLLHGYYHLKDTGVMAIVLPHGVLFRGGAEGKIRKALLENGAIDTVIGLPANI
                     FFNTSIPTTVIILKKDRAKKDVLFIDASQDFEKIKTQNTLRDYHIDAILEAYKTRTIK
                     DKYAYVAEFDEIVENDYNLNIPRYVDTFEEE"
BASE COUNT         1183 a          505 c          582 g          948 t
ORIGIN      
        1 ttcaaaaaaa aaccaaccga aagatataaa agatattgta gatacacgaa tgtataaaga
       61 acgtgatgac ttaaactata cgcttattat caataaagat ggaaactatt catggcgtcc
      121 tctcgttcta ctacatccta ttctatatgt agatttggtt aattgtctca ctaaagaaga
      181 ccattgggag gagttaaaaa agaggtttag tgaatttaaa aaagataaaa atattaactg
      241 ttattctata cctgttgaag cttccaaagg ttcaaaaagg acagatcttg gtgaaacaat
      301 actaaactgg tgggaatatt ttgaacaaaa aagcttagct cagaatatta aataccaata
      361 ttgcatgttt actgacatcg ctgattgtta tccatcaatt tatactcact ctataacatg
      421 ggccatgtat ggtaaagaaa aagttaaaaa tgatgaaaat aagtgttcgg gctcacttgg
      481 cgataaaata gataaaaaaa tatctggaat gcaacacaat caaacaaatg gtatccctca
      541 gggttccgtt cttatggatt ttgtagcaga gatcgttcta gggtatgttg atttgagatt
      601 atcgaaagaa ttaaaaaaat tagaaaattt aaaagattac aaagtactca gatatagaga
      661 tgattataga atattttcaa ataatcgtaa tgatttggaa caaattatga aagtgttatc
      721 agaagtctta tatgatttaa attttaagtt aaattctagt aaaacaaaat tatcagatga
      781 tattatcata gattctatca aaaaagataa gctctattgg gaagaaatta aggcaagtat
      841 aagaatgaat gccacaaact tagatggtga tagagaaatt cgttatagta taaatttaca
      901 aaaacattta ttggaaataa aaaagttagc agataagcat cctaattcag gccaattgaa
      961 aaaagcactt tctgagttta ataaagaacg cattattaaa atcacttcaa agccgaacga
     1021 tcttttacca cttattggta tcctggtaga tatcatgata aataacccgg gttctttgcc
     1081 gcagtgtgtc ttaattatag ggcagttatt aaatttcgaa aatgagagta aggctagaga
     1141 aatagttgaa atgattataa acaaatatgc tttaaagcca aatactgaat ttatgatgat
     1201 atggtttcaa agattgacca ccatttttgg agaaatgttt gatagtgttt tatcatccga
     1261 atttgtatct aaaatcaaag atcctgtctc taatcagatg ttttctgtag actggctaaa
     1321 tgaagatgct aagaaatctt tttatgaagg gaccattaaa gacgaagaga aatatattaa
     1381 aatgagtaag aaaatatata ttactgaatt tgatgatttt aatgattatc ctttttaagt
     1441 gaaaatttag aatgaatata aaaaacatta caatctaatt tttttaaaaa aatgttatat
     1501 cggaagtaat ctcttgattt ctatactata agataagaaa accactattt aacaaggtta
     1561 ttcgaacctt attttaagtt acttattatt taatgtatcg aaaaaggtga aataggtttg
     1621 ttataataag aattaagtaa gacatgaatt gtctaagcaa atgtagctta tccatttcat
     1681 taaaatacat atggtgaaaa aacaagttca aatagtaact aattttttaa aaaactgatt
     1741 tataaaaaat acaacacgaa tgaggaaaat aaccaatgac agaacaaatc gaaaaaaatt
     1801 caaaaagctt atatcaggca ctgtggaatt ccgcagatat cctgcgttca aaaatggacg
     1861 ctaatgaata caagagctat ttactaggct tggtctttta taaatactta tccgacaaca
     1921 tgctgcggta tgtctccgtt ctattggagg aagaaacgga cgacctaaat aaagcacaag
     1981 acctttacgt tgaagcattt aaagatgcag atataaagga tgatctcttg tatgaactaa
     2041 aagatgagtt ttcatatacc atcgcacccg cattgacctt taccgcgcaa gtggcagcca
     2101 ttcatgatgg atcttttcaa ttagaagacc tggtacaagg tttccgtgac attgaacaat
     2161 ccagcgaaaa ctttgagaac ttatttgaag acattgatct gtattctaaa aaactggggt
     2221 caaccccaca aaaacaaaat aaaaccatcg cagatgttat gaaagaatta gaagggttaa
     2281 acatggcggg gcatgctggc gatgtcttag gcgatgccta tgagtactta attggccaat
     2341 tcgcatctga atccggtaaa aaagccggtg aattctatac cccacaaccg gtcgcaaaat
     2401 tgatgacaca aattgtttta caaggaaaag aagataaaaa aggcttttct gtttacgacg
     2461 cgaccatggg ttcgggctcg ttacttttga acgctaaaaa atattcccat caaccgggaa
     2521 ccatttctta tttcggacaa gagttgaata cgtctaccta taatttggcg cgtatgaaca
     2581 tgattttgca tggggttccc attgccaacc aacacttgca taatgcggat accttggatc
     2641 aagactggcc aacagaagag ccaacgaact tcgatggggt gctcatgaac ccaccgtatt
     2701 ctgcaaaatg gtcggctgat aaaggcttct tagatgaccc acgcttctct gcctatggcg
     2761 tattagcccc taaatcaaaa gcggactttg ctttcttatt acatggctac tatcatttga
     2821 aagatacggg cgtcatggcc attgttttgc cacatggggt gctctttaga gggggcgcag
     2881 aagggaagat acgcaaagcc ttgttagaaa atggtgccat tgacaccgtc attggcttac
     2941 ctgctaacat cttctttaat acgtccattc caacgaccgt aattatcttg aagaaagacc
     3001 gtgcgaaaaa agatgtgctc tttattgatg cgtcacaaga ttttgaaaaa ataaaaacgc
     3061 aaaatacgct acgagattac catattgacg ctattttaga ggcctataaa acccgtacaa
     3121 ttaaagacaa gtatgcttat gtcgcagaat ttgatgaaat tgtggagaat gattacaact
     3181 taaacattcc ccgttacgtg gatacctttg aagaagaa
//
LOCUS       DAFEKH010000127         3199 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.135, whole genome shotgun sequence.
ACCESSION   DAFEKH010000127
VERSION     DAFEKH010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3199
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.135"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            301..585
                     /locus_tag="LP386_002909"
     CDS             301..585
                     /locus_tag="LP386_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920075.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            588..1004
                     /locus_tag="LP386_002910"
     CDS             588..1004
                     /locus_tag="LP386_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920076.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            complement(1141..1860)
                     /locus_tag="LP386_002911"
     CDS             complement(1141..1860)
                     /locus_tag="LP386_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBL1920077.1"
                     /translation="MDEKTELTVKYQNELNLVPLKNFNAKQMDLFFALCARMKDRGLK
                     KVRFSFEELKELSDYKMTATKAFVGDLEKLYKDMLNLTYRTEDEDSIRYFVLFTGFEI
                     NKTKKFVEVSVNPDLEYIINGLTAEFSRFELSAFTSLRSTYAKTLFRLLMQYRSTGYY
                     VVRIEEFRSLMDIPEYYQMGNIDQKVLNPALRELKKYFNDLKVTKIKAKKGNKIAKLE
                     FTFSSLTSDLPKISLRNWLEE"
     gene            2513..2608
                     /locus_tag="LP386_002912"
     CDS             2513..2608
                     /locus_tag="LP386_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HBL1920078.1"
                     /translation="MCFVFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            complement(2910..3155)
                     /locus_tag="LP386_002913"
     CDS             complement(2910..3155)
                     /locus_tag="LP386_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920079.1"
                     /translation="MRLEKEKMEKFPYEYFQNLEKLEQAIQAIKFDLTDEKLLEYKNM
                     TPERKRSLEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
BASE COUNT         1066 a          596 c          499 g         1038 t
ORIGIN      
        1 aaaaaaaatg tcgtttgaaa aactaaataa atttttgatc gtgcattttt aaatttggtt
       61 atcgattaca cgtgcagcac tcccccccga attttaaaga gcataaggaa acgtgtaccc
      121 actttctaaa aaaagtgggt agataggctg tgcctatcac gtttctcaga aaaaaatttg
      181 atatcacttt ttcgccatcg tgggtagctt atgtatagca ttttggcaaa aaacagctat
      241 acaaatatag tatttgtatg gtatacataa attatacata attgcaaaag gagatttttt
      301 atggacattt tagttcggaa tattgatcca aagtttgttg caacaataga caaacgttgc
      361 caagaactca cgaataaaac aggagaaaaa tggagtcgaa ataaatatct aaaagtttta
      421 atcgaaagtg attttgaccg tcaacttacg acttacaaaa aagaccaatt cgatttattg
      481 ctcgataaat ttattgctat ccaaacagaa aatactcaaa tattaagcga gtatgtctac
      541 acaaataatc aaatcattga aatgcttatc ggaggaatga tataaccatg agaaaaactt
      601 ctgtccaaaa acatgttact ttgtacccta gtcatgttga cgttttagat tccatcatcg
      661 aaaaaaatcc agatatcaat aactactcgg aagccattcg ctttttatgt atgagttatg
      721 aacccgatac caacacgacc actaccagca atcaggcaaa actaaatgct atgggaaaag
      781 aaatttccat catgactgaa atcatcgcag aatttgctga tttatatcta aaagatacag
      841 gcgttcttat tggcacaaat tctaaagtat atcaagaagt gaaagaaaaa atcgaagcta
      901 aactaaatcc atcaaatcga aatcgaccaa agaatcatca aaaagaaacc agtcaaacag
      961 tcacttctag aaatttcgac ccaacaaatt ttctaaaacg ataaaaaaca gataggagtt
     1021 attcctatct gttttttatt tagaagcccc atacaatatg ctagaatgta ctagcaatct
     1081 tagtcggttg taagggactt gtctacttgc ttaatgtaag gggggcgagt tcttttttat
     1141 ttattcttct aaccagttac gcagagaaat ctttggcaaa tctgacgtta ggcttgaaaa
     1201 agtaaattct aatttggcga ttttattgcc cttttttgct tttatttttg tgactttaag
     1261 atcattgaag tattttttta gttctcgtaa tgcaggattt aatacttttt gatcaatgtt
     1321 acccatttga tagtattctg ggatatccat taagctccta aactcttcaa tacgaactac
     1381 ataataacca gtagaacggt actgcataag cagtcggaat agagtttttg catacgtaga
     1441 acgcaacgac gtgaaagcag ataattcaaa tctactaaat tcagctgtta aaccattaat
     1501 aatatattct aggtccggat taacactgac ttcaacaaac ttttttgttt tattgatttc
     1561 aaaaccagta aacaaaacaa agtagcgaat agaatcctca tcttcagtac ggtaagtaag
     1621 attaagcata tctttataga gcttttctaa atcaccgaca aaggcttttg tagcagtcat
     1681 cttataatca cttaactctt ttaattcctc gaaagaaaat ctaacttttt tcaaaccacg
     1741 atctttcata cgagcgcata atgcaaaaaa taaatccatc tgcttagcat tgaaattttt
     1801 cagcggtact aaattcaatt cattttgata tttgactgtt aattccgttt tttcatccat
     1861 tcctttcttc cccccttaca aataaataat aacctttaac aaccaactcg taaataggtt
     1921 ggttgttatt atacaaaagg atattagtac tcagataaaa agttgttagt actcagataa
     1981 aaagttgtta gtactcagat aaaaagttgt tagtactcag ataaaaagtt gttagtaccc
     2041 ttctgtatcc gttgggagag taaggctcaa ctgcccccta aaaagggttc taaaaaatct
     2101 ttaaaaaata aataaaataa acgcgcgcgc gcgagcaaaa tttcccgcca aaaaatcacc
     2161 cactttttaa aataaacagg ttcgcgcatg atattaaact gccaatctag ctccctatgg
     2221 tcgctgtaag aaggagtgat cgctacgctc tcacatttta cttgcagcag tcgcctttag
     2281 gctccttcgc caaaaataat tcattaggga ctcctttgtg gcgtcctgag agctcgtcta
     2341 agccgttcta agacaagatt cgataaaaac tatgtccttc gttctaaagc gccttacagg
     2401 cggtcagggc aagccctaac aaccccaagg caataaaaaa cttaggctta tttttgcttt
     2461 tttattgtat aattgattgt cgcctatccg acagtcttgc gactggaagg aggtgtgttt
     2521 cgtgttcact aactttattt gctcccttct tgttgggctt ttaagcgctt tgttcagtta
     2581 ctggttgaat aaccgaaaca agaagtaaaa cttaattaag gcgactcagc ccacaaaaaa
     2641 agccccagag aatccgacct ctctggggct ttcgtgtgtt tcgtgttcac ttatttgcaa
     2701 tcaaattata acagaaataa atatttattt caaaaatatc ctacaaaagt ctaaaatccg
     2761 taattatttc ttatatgcaa catttacaaa taaagtcgct ctgagagctc gtatttttcg
     2821 atttaagacg ttttatttag tttttggtgt atttcattgg tccaagctaa aaaactctta
     2881 gaagcgattt tagagccatt taaacccact taattatatt ctccatgaaa ttcgctccat
     2941 gcgtcaaaag ctgcgtctga aattccgccg tcttcgttca ctagttgcat taatttttcc
     3001 aaagatcgtt ttctttcggg tgtcatattt ttatattcca acaatttttc gtctgttaaa
     3061 tcgaacttga ttgcttgaat tgcttgctct aatttttcta agttttgaaa atattcgtaa
     3121 ggaaattttt ccattttttc tttctccagt ctcacaattt ttctagaaat aaaatcactt
     3181 ctttgccgtc tatactctc
//
LOCUS       DAFEKH010000128         2928 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.136, whole genome shotgun sequence.
ACCESSION   DAFEKH010000128
VERSION     DAFEKH010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2928)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2928)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2928
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.136"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            5..2377
                     /locus_tag="LP386_002914"
     CDS             5..2377
                     /locus_tag="LP386_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920080.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQRKTNGQ
                     PMNDKRNGHSWFRQQERLENKVHSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIENIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKERSEKGKENLLPEVQAI
                     IDSGRVTQWKKNPTIYFLKDYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKENDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQTVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTVETAENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2438..>2928
                     /locus_tag="LP386_002915"
     CDS             2438..>2928
                     /locus_tag="LP386_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920081.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDSKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKHERQNF
                     LVR"
BASE COUNT         1172 a          465 c          636 g          655 t
ORIGIN      
        1 ggacatggca gaagaaaaag aaccactaga caatagtcgc ttgggaaaat ccaaaagaaa
       61 attagtacga ttgcaaaatg aattaaacga acaaattgag aagatgtttg aacaccagag
      121 aaagaccaac ggtcagccaa tgaacgataa gagaaatggg cattcttggt ttaggcaaca
      181 agaacgttta gaaaacaaag tgcatagtct gagagaagag atcaagcaac aagaaaaaca
      241 ggtagaaaaa cttgaaagac aagaagagct aaaggaaatg ggctataaca agtacggcgg
      301 cctggatatg acaatcgaaa atattccaag aatcaaagaa gaaatcgaac gctttgaaaa
      361 aggtgaatcg actttttcag ccgctacgat ccgaaaatac caacggaaat tggaaacatt
      421 agaacagctg aaagaaagat cagaaaaagg aaaagaaaat cttcttcctg aagtacaagc
      481 aattattgac agcggacgag tgacgcaatg gaaaaaaaat ccaaccattt attttttgaa
      541 agactatcga aaagttgctt tagaactgaa tgaaaacggg ggatttgagg aatcaaaaaa
      601 ataccaagcc acgtcggaag aggaaaaagc agctgttcgt gaattacttg aagaggctgc
      661 gccaactgat tctttgaagg agaaagaaaa cgatcatttc tatcgagtag aattcaacga
      721 aaatgatcca gaaaaaggat tgaaaagtta tggtggggag atcgtaacat tagaattgat
      781 cgatcaactc aaaacgttgg ataaccaata cgccgcagaa gcaggttatt ataaattcta
      841 ttttgaagaa gtgaagaacg gagaagtagt cgatcagatc cgaatggatc taggggatgg
      901 cgtcaacagt aatcaaccca tctatttaga gttagcaaaa ttgtgcgaac aagtacctga
      961 aaaggaacaa aaacaaacgg tcaaaaatga acctgtttcg aaagaacaaa tgcagtcgaa
     1021 agaaacaaaa acaaaacaaa agggctatca aaaacgaacg gcagaagaga ttaagcaaga
     1081 agtcaaatcc ctttcgcaac aggcactgga tgcggtgaaa aagcataccc attctcctga
     1141 agacgtgaaa gaacttttga attttatgtc tcgttttcca gaacgatcct ttagaaatca
     1201 attattgatt gaggaacaat ttccaggtgc aacggcttgt ttaggtcgtg ctgcgttgaa
     1261 aaaagaagga atctatatca aaaaagggga acaagggaac aagatctttg tcagaaaaac
     1321 ggtcaaagga ttttatgaga aaggacgtgg ctttgttcga gaaacagaag ctacaccaga
     1381 agataaaaaa cgaatcgaaa gtggtcaaat cgaagtgatc aaaaaacctt actacacgat
     1441 tgaaaaagtg tttgatatca cacaaacaca gttaaaacct gaagactatc cgaaaatctt
     1501 tccgaaccgt gtctttgatt ttcaattgga taaaaaagga cagtcagaac ttcaagctgg
     1561 gattcaagcg gtagccaaca atattggaat acaaattcga gatatgacag aaagtgaagt
     1621 ctatcaaaga gaattaggac aagcacgggg ggcgtatgtt cgtaacgaat ttactggcga
     1681 agaagaaatc gtcatgaata ctcgaaatac tcctacgcag catttagcta caagtattca
     1741 tgaattagcc catgcaagaa tgcacaaatt ttcagaatta gataccgcaa ctaaagaatt
     1801 gcaggcagaa atgacttctt atattgtgtg caaacatttt ggaatggaca cttcggagaa
     1861 agctattcct tatattgcag catggacgaa gaatggtcag acgttggatg ataaggaagc
     1921 ggcggaacgt gggaaaatca tgaatgatgt cagccgtgtc gcaaatgaat tcattcaaac
     1981 catttctaat gaaatcaatc aatacagaga aagagaacca gagatccaac cagcagaagt
     2041 gaagcaggag cataaaaata ctgtagaaac ggcagagaat aagaatattg tgcccgttgg
     2101 ttcactttgg atcgacaaga aagacgggaa agtaatggaa gaagatacgg gtcgaacgtt
     2161 acatttgaag gatgcggcgt ttattgaaga tccgcagcat aatcaagtga ttttaaaagg
     2221 aaaaagttat ggaaaagaga ttcaaacggc gttaccttca gaagaatttg cgctaggaaa
     2281 tccattccga ttttcacttg aaacagtgtc agaagtggcc aaacgaaaaa atgaaatcta
     2341 ttatgaacaa caattgtcac aaaaagaacg cgtataaaac aagtaaaaaa gactatctga
     2401 aaaacggata gtcttttttc ttttgggagg tttgaaaatg accgaaaaaa aaatgagtct
     2461 tattgatcga tgtaaacaga tcgatatagt ggattttgct cgaaacaatg gaatggctgt
     2521 agtcaataaa ggacgagact atcgcttaga agaccatgat tcatttgttt ttgatcgaag
     2581 aaaacaacgt ttttattgga acagtcaaaa tattagtggc gacattattg aattagctaa
     2641 actttttttc atagacaaag agatccaaga ctctaagcaa caatttaaag cagccacaga
     2701 ttttattcta aagaatgaag acaaaacaga acgagtagaa aatcttcatt ttgagacaga
     2761 aaagtacaaa gatcaccccg ttgattatca accactcaca gaaaaaggaa ggaattatct
     2821 gaaggaagaa cgaaaactac cagagtggct gattgattat gcagaaaaag aagggttgat
     2881 tgccgaacta aagccaaaac atgaacggca aaatttctta gttcgaga
//
LOCUS       DAFEKH010000129         2842 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.138, whole genome shotgun sequence.
ACCESSION   DAFEKH010000129
VERSION     DAFEKH010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2842
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.138"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            204..1172
                     /locus_tag="LP386_002916"
     CDS             204..1172
                     /locus_tag="LP386_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HBL1920082.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1165..2196
                     /gene="vanA"
                     /locus_tag="LP386_002917"
     CDS             1165..2196
                     /gene="vanA"
                     /locus_tag="LP386_002917"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HBL1920083.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2202..2810
                     /locus_tag="LP386_002918"
     CDS             2202..2810
                     /locus_tag="LP386_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HBL1920084.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT          840 a          548 c          691 g          763 t
ORIGIN      
        1 aattttttag gaaaatctca aggttatctt tactttttct taggaaatta acaatttaat
       61 attaagaaac ggctcgttct tacacggtag acttaatacc gtaagaacga gccgttttcg
      121 ttcttcagag aaagatttga caagattacc attggcatcc ccgttttatt tggtgccttt
      181 cacagaaagg gttggtctta attatgaata acatcggcat tactgtttat ggatgtgagc
      241 aggatgaggc agatgcattc catgctcttt cgcctcgctt tggcgttatg gcaacgataa
      301 ttaacgccaa cgtgtcggaa tccaacgcca aatccgcgcc tttcaatcaa tgtatcagtg
      361 tgggacataa atcagagatt tccgcctcta ttcttcttgc gctgaagaga gccggtgtga
      421 aatatatttc tacccgaagc atcggctgca atcatataga tacaactgct gctaagagaa
      481 tgggcatcac tgtcgacaat gtggcgtact cgccggatag cgttgccgat tatactatga
      541 tgctaattct tatggcagta cgcaacgtaa aatcgattgt gcgctctgtg gaaaaacatg
      601 atttcaggtt ggacagcgac cgtggcaagg tactcagcga catgacagtt ggtgtggtgg
      661 gaacgggcca gataggcaaa gcggttattg agcggctgcg aggatttgga tgtaaagtgt
      721 tggcttatag tcgcagccga agtatagagg taaactatgt accgtttgat gagttgctgc
      781 aaaatagcga tatcgttacg cttcatgtgc cgctcaatac ggatacgcac tatattatca
      841 gccacgaaca aatacagaga atgaagcaag gagcatttct tatcaatact gggcgcggtc
      901 cacttgtaga tacctatgag ttggttaaag cattagaaaa cgggaaactg ggcggtgccg
      961 cattggatgt attggaagga gaggaagagt ttttctactc tgattgcacc caaaaaccaa
     1021 ttgataatca atttttactt aaacttcaaa gaatgcctaa cgtgataatc acaccgcata
     1081 cggcctatta taccgagcaa gcgttgcgtg ataccgttga aaaaaccatt aaaaactgtt
     1141 tggattttga aaggagacag gagcatgaat agaataaaag ttgcaatact gtttgggggt
     1201 tgctcagagg agcatgacgt atcggtaaaa tctgcaatag agatagccgc taacattaat
     1261 aaagaaaaat acgagccgtt atacattgga attacgaaat ctggtgtatg gaaaatgtgc
     1321 gaaaaacctt gcgcggaatg ggaaaacgac aattgctatt cagctgtact ctcgccggat
     1381 aaaaaaatgc acggattact tgttaaaaag aaccatgaat atgaaatcaa ccatgttgat
     1441 gtagcatttt cagctttgca tggcaagtca ggtgaagatg gatccataca aggtctgttt
     1501 gaattgtccg gtatcccttt tgtaggctgc gatattcaaa gctcagcaat ttgtatggac
     1561 aaatcgttga catacatcgt tgcgaaaaat gctgggatag ctactcccgc cttttgggtt
     1621 attaataaag atgataggcc ggtggcagct acgtttacct atcctgtttt tgttaagccg
     1681 gcgcgttcag gctcatcctt cggtgtgaaa aaagtcaata gcgcggacga attggactac
     1741 gcaattgaat cggcaagaca atatgacagc aaaatcttaa ttgagcaggc tgtttcgggc
     1801 tgtgaggtcg gttgtgcggt attgggaaac agtgccgcgt tagctgttgg cgaggtggac
     1861 caaatcaggc tgcagtacgg aatctttcgt attcatcagg aagtcgagcc ggaaaaaggc
     1921 tctgaaaacg cagttataac cgttcccgca gacctttcag cagaggagcg aggacggata
     1981 caggaaacgg caaaaaaaat atataaagcg ctcggctgta gaggtctagc ccgtgtggat
     2041 atgtttttac aagataacgg ccgcattgta ctgaacgaag tcaatactct gcccggtttc
     2101 acgtcataca gtcgttatcc ccgtatgatg gccgctgcag gtattgcact tcccgaactg
     2161 attgaccgct tgatcgtatt agcgttaaag gggtgataag catggaaata ggatttactt
     2221 ttttagatga aatagtacac ggtgttcgtt gggacgctaa atatgccact tgggataatt
     2281 tcaccggaaa accggttgac ggttatgaag taaatcgcat tgtagggaca tacgagttgg
     2341 ctgaatcgct tttgaaggca aaagaactgg ctgctaccca agggtacgga ttgcttctat
     2401 gggacggtta ccgtcctaat cgtgctgtaa actgttttat gcaatgggct gcacagccgg
     2461 aaaataacct gacaaaggaa agttattatc ccaatattga ccgaactgag atgatttcaa
     2521 aaggatacgt ggcttcaaaa tcaagccata gccgcggcag tgccattgat cttacgcttt
     2581 atcgattaga cacgggtgag cttgtaccaa tggggagccg atttgatttt atggatgaac
     2641 gctctcatca tgcggcaaat ggaatatcat gcaatgaagc gcaaaatcgc agacgtttgc
     2701 gctccatcat ggaaaacagt gggtttgaag catatagcct cgaatggtgg cactatgtat
     2761 taagagacga accatacccc aatagctatt ttgatttccc cgttaaataa acttttaacc
     2821 gttgcacgga caaactatat aa
//
LOCUS       DAFEKH010000130         2778 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.139, whole genome shotgun sequence.
ACCESSION   DAFEKH010000130
VERSION     DAFEKH010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2778
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.139"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..197
                     /locus_tag="LP386_002919"
     CDS             <1..197
                     /locus_tag="LP386_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920085.1"
                     /translation="WFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLIIAIIAVGLV
                     FNAAGVKDILLELFNRIIGA"
     gene            314..811
                     /locus_tag="LP386_002920"
     CDS             314..811
                     /locus_tag="LP386_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBL1920086.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSISELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMSDVARYYIEETGALGEVPASLQNYIDYESYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            898..1290
                     /locus_tag="LP386_002921"
     CDS             898..1290
                     /locus_tag="LP386_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL1920087.1"
                     /translation="MKKIRSYTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAV
                     MILGNLPPLSMIEGAFLKYFGIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRRKLTY
                     AGKKVTLGRNQPQEAITAVRSEFYGISN"
     gene            1274..>2778
                     /locus_tag="LP386_002922"
     CDS             1274..>2778
                     /locus_tag="LP386_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL1920088.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSILSAQERSKNEVTGKLKTVAYDKIDQQTDALISM
                     IGENQVDYRFFIGFKLLLNDQEFSMKSLTVEAKNAFTDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYPLSKKKLEH
                     ETLIKTYDLIKPTRCLVEEKQRYLKIQQEDETAYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKA"
BASE COUNT          839 a          518 c          596 g          825 t
ORIGIN      
        1 actggtttct atcaaacgct caatcactgg tgcttttagc aatcgttgtg attggcttgt
       61 atcttggctt caagcgtgag tttagcaaac tgattggctt tttaattatt gcgattattg
      121 cggttggctt agtcttcaac gctgctggag taaaagacat tttactagag ctattcaatc
      181 gcattattgg tgcttaaata aaaccgttct tttgtggaat ataagtggtt ttcttatgtt
      241 ccgcaaagga atggtacacc aaacgaagtg cggtagggat ttttgaatct ctacaaagaa
      301 aggacgtgaa tatatggacg atatgcaagt ctatattgcg aatttaggca aatacaatga
      361 gggcgaattg gtcggtgcgt ggtttacctt tcccattgac tttgaggaag tcaaagagaa
      421 aatcggcttg aatgatgaat atgaggaata cgccattcat gattacgagt taccctttac
      481 ggttgacgaa tacacttcta ttagcgaact caatcgccta tgggaaatgg tatcggagtt
      541 gccagaagaa ctacaatcgg agctatctgc tctgctcact catttttcaa gtattgaaga
      601 actaagcgaa catcaagaag atattatcat tcattccgat tgtgatgata tgtctgacgt
      661 ggcacgctac tacattgaag aaacgggtgc tttaggcgaa gtgccagcca gtcttcaaaa
      721 ctatattgat tatgaatcct atggtcggga tttagacctt tcgggaacgt ttatctcaac
      781 caatcacggg atttttgaaa tcgtctatta aatctgtcgg tacattctta ctggcagatt
      841 ttcttgttta cggggtagtc aaaagactat ccccattttt atgaaaggat tgattacatg
      901 aagaaaatac gaagctatac cagtatctgg tctgttgaga aagtgttgta ctccatcaat
      961 gactttagac ttccgtttcc cataaccttt acgcaaatga catggtttgt cgtgtcactc
     1021 tttgcagtta tgatacttgg caacttgccc cctctttcta tgatagaggg agcatttctc
     1081 aaatactttg ggattcctgt ggctttcaca tggtttatgt ctacaaaaac ctttgatggt
     1141 aaaaagcctt atggattttt gaagtctgtc attgcttatg cactgcgacg aaagctgacc
     1201 tatgcaggaa aaaaagtaac gcttggcaga aaccagccac aagaagccat tacagcagtt
     1261 aggagtgaat tttatggcat atccaattaa atatattgaa aacaatctgg tctggaataa
     1321 agatggggaa tgttacgctt actatgagct tgttccctac aattactcat ttctaagtcc
     1381 ggaacagaaa atacaagtac atgattcttt cagacagctt atcgcacaaa atcgtgatgg
     1441 caagattcat gctttacaaa tcagtacaga atccagcata ctttctgcac aagaacgttc
     1501 caaaaatgaa gtcactggaa agctcaaaac ggttgcctat gacaaaatcg accaacagac
     1561 agacgcttta atatccatga ttggcgaaaa tcaagtggac taccgtttct ttatcggttt
     1621 taagttgctt ctcaacgatc aggagttttc tatgaaaagt cttaccgttg aagcaaaaaa
     1681 tgcttttact gattttgtct atgatgtgaa ccataagctg atgggcgatt ttgttagtat
     1741 gagtaatgat gaaatcctgc gttttcagaa gatggaaaag cttttagaaa ataaaatctc
     1801 ccgtcgtttc aaaatccgaa gattagataa ggatgacttc ggctatctga ttgaacacct
     1861 ttacggacag acaggcactg cctatgaaga gtatgagtat cctctatcaa agaaaaagct
     1921 ggaacatgaa acactgatta aaacctatga cctcattaag cctactcgct gtctggtgga
     1981 agaaaaacag cgatatttga aaatccagca ggaagacgaa accgcctatg tagcttactt
     2041 taccatcaac agtattgtcg gcgaactgga cttcccgtcc tctgaaatct tctactacca
     2101 gcaacagcaa tttacctttc cgattgatac gtcaatgaat gtggaaattg tagcgaatcg
     2161 taaagcccta tctactgtcc gcaataaaaa gaaagaactg aaagacttgg ataaccacgc
     2221 ttggcaaagt gataatgaaa ccagctctaa tgtggcggaa gctctggaaa gtgtgaacga
     2281 gctggaaacc aatttagacc aaagcaagga atctatgtat aagctgtcct atgttgtaag
     2341 ggtatcagca aatgaccttg acgaacttaa acgtcgttgt aatgaagtga aagatttcta
     2401 tgatgatttg agcgtgaaac tggtacgacc ttttggggat atgctgggct tacatgaaga
     2461 atttttacct gccagcaaaa gatatatgaa tgactatatt caatacgtga cctctgattt
     2521 cctcgctggt ttaggttttg gtgctactca aatgctgggt gaaaatgagg ggatttatgt
     2581 tggctacagc ttagatactg gacgcaatgt ctatctgaaa cctgctcttg ccagtcaagg
     2641 ggttaagggt tcagtaacca atgcgttagc gtctgccttt gtcggttcgc tgggtggtgg
     2701 taaatccttt gcgaataacc ttatcgtcta ttatgcagtg ctttatgggg cacaagcagt
     2761 gattgtagac ccaaaagc
//
LOCUS       DAFEKH010000131         2746 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.140, whole genome shotgun sequence.
ACCESSION   DAFEKH010000131
VERSION     DAFEKH010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2746
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.140"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            226..894
                     /locus_tag="LP386_002923"
     CDS             226..894
                     /locus_tag="LP386_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HBL1920089.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(1094..1324)
                     /locus_tag="LP386_002924"
     CDS             complement(1094..1324)
                     /locus_tag="LP386_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920090.1"
                     /translation="MTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGE
                     AYEDYFMIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(1451..2692)
                     /locus_tag="LP386_002925"
     CDS             complement(1451..2692)
                     /locus_tag="LP386_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBL1920091.1"
                     /translation="MSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPS
                     DLYIVAPRMAYYMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYD
                     MAKLIHKDVFEQTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKI
                     SDITDFWGIGKRTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSF
                     LGQEYTPKSKSIGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVG
                     YSLGYLDPNGKTGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVY
                     ATGLQLNLFEDPEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGG
                     HAGGMSGLEGGKDETDSKKIH"
BASE COUNT          780 a          549 c          542 g          875 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacggt tgtgtaaaaa tatcatttta gagcataaaa
       61 aaaaggagtg gatttctcca ctccaaaaaa gtctaacttt tgggggtcac tacagtgtca
      121 cagtcctttt tttagtaaaa ggatacattt cttccttgta tattccatgc gtgttcgtga
      181 gaaagcatat ataatttaat taacagatag ttagggggag aaaaaatgat tttttcaatt
      241 acaatgaaac tggtgttcgg gttgatcggt ttattattag tggtacgttt gcttgggaag
      301 aaatccatgt cagaaatcac accgtttgat ttagtctata cgcttgtttt aggtgggatc
      361 ttagaagaat caacctatga tgacaatgtc catgtagggc atgtcctatt tgccattgcg
      421 ctttgggcag taatgattta tggtatcgaa cgtatcgtcc aaaaaaatga aaaggtcaat
      481 cgttgggtca aaggcgagcc atctgttcta atcaaagacg gcgtcatcaa catgacagag
      541 ttgacaaata accatatcga gatggagcag ttgcgagcaa tcttaagaca gcaagaatgc
      601 ttttttcttg aaaatgccaa acatgttatc ctagagaatg ccggtcaaat gagtgtattg
      661 aaaaaatcag atgaagacaa agctttatcg atcctgcttg tagatgaagg gcaaattcag
      721 cataaagtgc ttcagtccaa tcaattgact gaagcatggc ttatggagaa cttgaagaaa
      781 gaaggctatg cagatgtaaa acagctgatt tatgttgaat ggtcagaaga aaaagggctc
      841 tacatactaa ataaagaaga cgtcatgcat gaatcttacc gaatagatgg atagatagac
      901 agaggttgtg aaatcagcgc cttggcttgt tactcaaaac taagcgactt tttcacaacc
      961 tctgatatct aatatacgtt gttccagaag ttgcttcttc gaaaaataag ccaaaattcc
     1021 acaaaaattt aagaagcaat tttcgaaaaa tcctttctta ttttttgaag ttgatcactt
     1081 ctgtcacaac ctctcatgtc acaaaccatt tttttgtttc ctttaactca atataccgta
     1141 cgtcttccca caatatcggc tgatggtcaa tcataaagta atcttcatag gcttcaccaa
     1201 tgaagtgccc ttcgacctca tccaagagtc ttccaaattc atcttttaaa ttgagctgaa
     1261 tgattactgc tttacgagat aaaaaggctt ctgtcagtat actatcgatt tcttgcaatg
     1321 tcatttgttg tttaggaaga ggctgtttgc gtgcttcttc ttcatttttt tgataccgtt
     1381 gactagttct tccatcgcaa aagcagtccc ccattttaat ccaaatggcc gatctcgata
     1441 ctcgttatag tcaatgaatt tttttgctgt ccgtctcatc ttttccacct tctaatccac
     1501 tcataccacc tgcatgcccg ccaacgagag aactacgtgc gatggcgcgt cctccttgca
     1561 agagactatg cgcatggatg attgattgaa agccgtattt ttttctaatc gtatcgacaa
     1621 caaaatcaac tttcgcttca tttatctgct tttcaggatc ttcaaaaagg ttaagctgta
     1681 aacctgtcgc gtatacgagg tcggaacagt tcacgcctac acgccgaata tcctggtagt
     1741 ggtaatgctg gtggaaaatg gtcaataaag catctgctag atctctgcta gcatttgtcg
     1801 cttcgatttt catttgctgg tgaaacccgg tcttgccatt tggatcaaga tagcctaaag
     1861 agtatcctac ccataagctg actacttgtg tttttgctgc agatcgtctc aagcgagtgc
     1921 cgacttggtc ggccatttct ttgataacga tctcgatttc ttctcgtctt gtataatctc
     1981 tatctaggat ttgactattt ccgatacttt ttgattttgg tgtatattct tgtcccaaaa
     2041 aacttcgatc gatgccccaa gcatgggcat aaagctgagt accgatgacc cctagcttgc
     2101 ttttcaagtg ataataatcc gcgtgagcta aatcataaac agaatgtata cccatttgtt
     2161 tcagacgttt tgctgttcgt ttgccgattc cccaaaagtc agtgatatct gagattttcc
     2221 ataacttttc tggtacatct tcataacgcc attcagcaaa catttgcttt ccgtcttttg
     2281 agccattgtc taaggctagt ttagcaagta gcgggttatc gccaattcct atagtcgtgt
     2341 agattccggt ctgctcaaac acatctttat ggatcagttt agccatgtcg tacgcatttg
     2401 ttttaccaaa gagtgccatg ctatttgtta catcaaggaa gctttcatcg acggaataga
     2461 catgatggtt cgcttcgtct gcatattttt tatagataga attgatttct ctgttctttt
     2521 ccatataata ggccatcctt ggggcaacaa tatataaatc acttggatag gggaagggaa
     2581 gatctctggc acggctgata ttggtgatgc cgtaagcttt ttttgctgca ggactggaag
     2641 ccaagattaa tccgctaccc cgtgtttctg tcgaatcgga cggataggac atgactacta
     2701 atttagttgt aaggggatca agatcctttt caacgcactc tacgga
//
LOCUS       DAFEKH010000132         2719 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.141, whole genome shotgun sequence.
ACCESSION   DAFEKH010000132
VERSION     DAFEKH010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2719
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.141"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            700..2610
                     /gene="ltrA"
                     /locus_tag="LP386_002926"
     CDS             700..2610
                     /gene="ltrA"
                     /locus_tag="LP386_002926"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBL1920092.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
BASE COUNT         1065 a          420 c          556 g          678 t
ORIGIN      
        1 aaaagctaag gcactaataa aagaacgaaa aagtttggtt attaggagaa ctgataatct
       61 gacaggtgga atgatgaagt aacgctctga aacgcctgcc ctgagcctcc gacaagcatt
      121 gtatgaggaa actcagaatg tttgaagctc ggtaaagacg gctgaaagat accgtaatag
      181 ttgatgaaca tatatcttct atcgaaaact atccagaggt gggtagcgta tccaacaggt
      241 cgggggtcta taaaatatct atggttagaa tgttctataa ggaactgacg aaacagcgaa
      301 tgtacgggtc taaatttgaa ctttgtagaa atgcaaaggt acgagaaatc gtagctggtg
      361 tggcaaagta agaatatagg ttatgaaatg ccatataacg ttacaggcgg tatcaagcca
      421 gcaggcttat agctagtgac ctaaggatat atatgtatag ataagattat cggaacgagg
      481 aaaggtattg ggttctcatc aagagaataa actgacgaag aacaataagc agttgaacta
      541 atgctgaaaa gcagagggcg aacctaagaa attcttgtaa tgagaatgga ggaatgccct
      601 caagtcgtgt atatattaga aaagtattat gttgtttcaa taaggattac gagtaagata
      661 aaaaagctca ctcaatttca agtaaaggag tgaagcctta tgcctaaaaa taaaaatgaa
      721 acattgtgtg tagaagattt aagacacgct gaatattacg aaatgcaaaa cacctttgat
      781 gatttatatg ccaaaagtaa gaatggagat attttcactc atcttatgga tattatccta
      841 tcgagagaaa atatattact ggcatatcga aatatcaaag caaatgcagg cagtaaaaca
      901 gcaggaacag acggtacaat aattaaagat attggcaaat tgccagcaga aacagttgtc
      961 aaaaaagtaa gatacattgt tgcaggcagt ccacatgggt atcgacctaa gccagtgagg
     1021 cgaaaagaaa taccaaaacc aaatggtaaa accagacctc taggtattcc ttgtatgtgg
     1081 gacaggctta tacaacaatg tataaaacaa gtattagaac caatctgcga agctaaattt
     1141 agtgaaaaca gctatggttt tagacctaat aggtcagttg aaaatgcaat aaaagcaacc
     1201 tataaccgcc tacaaatcag ccagctacat tatgtgattg aatttgatat taagggtttc
     1261 tttgacaacg tgaaccattc caagctgata aaacagatat gggctatggg aatacgggac
     1321 aagcacttga tattcatttt aaaaaggata ttaaaagctc caatcaaaat gactaacggt
     1381 acaataacat atccagagaa aggaactccg caagggggaa taatatcccc actactagca
     1441 aacattgttc ttaatgagtt agaccattgg gtagaaagcc aatggcagga aaatcctgtt
     1501 acaaaaaact atgtggttca tatcaataaa agcggtagcc catgtaaaag caacgcttac
     1561 aaagaaatga agaaaacaaa gttaaaggaa atgtatatgg ttcgttatgc agatgatttt
     1621 agagttttct gccgctacaa ggaaagtgct gaaaaagcca aaatagcaat cactcaatgg
     1681 attgaacaac gattaaaatt ggaagtatca caagaaaaaa caagaattgt aaatgttaga
     1741 aaaagatact ccgactttct tggtttcaag attaaaatga taccgagaag aaagaagtta
     1801 gttgttaaat cacatataag tgataaacaa ttcaaaaacc aaaaagacaa gctggtatca
     1861 caggcaaaga aaattgcttc tccctcaaaa gggaaaacgg aattagaaga aacaagactt
     1921 tataattcaa tggtattagg tatgcaaaat tattatcaga ttgcaacgaa tgtaaatctg
     1981 gattgtatga aactgaatag agctgtaatg gctatcttca ctaacagatt aggtacaaac
     2041 aaaaggggca gattgagaaa aacaggcaga caacttacga caaaggaggc aacaagatat
     2101 ggtaaatcta aaatgcttcg gtatgttgct ggcgagggcg aacctatttt ccctgttgga
     2161 tatatccaac acagaaaacc aatggcaaag gtgtatttag cgaattgcta cactctagag
     2221 ggaagaaaat ttatccacac caatctaagt gttgataaat tactgatgta ccagttaatg
     2281 aaattatctt tggaaaatcg cacaatagaa tacgcagaca atcgaatttc gctattttct
     2341 gctcaacatg gaaaatgtgc tataactctg gaagaatttc aacaagctaa tgaaatacat
     2401 tgtcatcata ttgtaccaac tggagctggt ggaaatgacg attataaaaa tcttattttg
     2461 gtaaaagagg cggtacaccg tctaatacac gctaaaacag aagaaacaat acaaaaatat
     2521 atagctctat tgaagctaaa taaagtccag ctcataagac taaataaata tagagtatta
     2581 gctggcaatc aagaattaaa cttgatatag gtctactaca taaatacttt tcaatataaa
     2641 cacgatggaa cgcggagtgc ggtgaaagtc gcacgctccg tgtgaatggg gggaaaagtt
     2701 tgagatattt ataatatca
//
LOCUS       DAFEKH010000133         2668 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.142, whole genome shotgun sequence.
ACCESSION   DAFEKH010000133
VERSION     DAFEKH010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2668)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2668)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2668
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.142"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..318
                     /locus_tag="LP386_002927"
     CDS             <1..318
                     /locus_tag="LP386_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1920093.1"
                     /translation="KAIIPENLDEVKLYLWEDNGEIVGFSGVSAEELVMLFLDPDFIG
                     KRYGSQILIELIETEDIKRIDVNSQNKYAKHFYLSHGFEIESEEDLDGFGKPYPITHL
                     VKK"
     gene            732..1550
                     /locus_tag="LP386_002928"
     CDS             732..1550
                     /locus_tag="LP386_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBL1920094.1"
                     /translation="MNKNPHNLKLVAVDMDGTFARTDYTYDIPRFKAVLSRMKAVDCQ
                     FVVASGNQYYQLRSLFPNYYDELSFVAENGAFVKDKTEVLFSADMPRKAIEVVLDLCK
                     DYPEVKNVMCGLNSAYCERGKVSQAFFDLTNIYYHRLEWVADFAEVQDKILKFAPTMP
                     VEKTEFYVELFREKLAGLLVPTSSGHGSVDLILSECHKTFGLKMLVERLGINPDQCVA
                     FGDGGNDIEMLEYCGLSYEMDNATEAVKQVAKHQCPSNDEDGVLVTLDRLFPNT"
     gene            complement(1623..1982)
                     /locus_tag="LP386_002929"
     CDS             complement(1623..1982)
                     /locus_tag="LP386_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBL1920095.1"
                     /translation="MSDNLFLEVQPEVFKQVPRLKDGFLLTLNDGSNQFSSAEGCCMI
                     GDHFLLVSTQHYIPAYDLTIPCEEATVKTSEYDTTFINGHLVLEVTPSNQTIRLKNES
                     GILDSNVQVYFDSSDAS"
BASE COUNT          924 a          372 c          471 g          901 t
ORIGIN      
        1 aaagcaatca ttcctgagaa cttagatgag gttaaacttt atttatggga agataacgga
       61 gaaattgtcg gttttagtgg tgtaagtgca gaagaattag ttatgctatt tcttgatcca
      121 gattttattg gtaagcgata tggtagtcaa atattaattg agctgattga aactgaagat
      181 ataaaaagaa ttgatgttaa tagtcaaaat aaatatgcaa aacattttta tttaagccat
      241 ggatttgaaa ttgaatctga agaagactta gatggttttg gtaaaccata ccctataacg
      301 catttagtaa aaaaataatt catgaatggt ttattacctg attgaacatg aataaaagta
      361 atatttttat tttgatggcc tatttctagg ttatgaatta tccagatcaa atttgtgtat
      421 tacattcagt aataaggtgc ttatcttagg atcaacttat gatactagct gaccaaggat
      481 gtaccagtta tagaaaatca gttaaagtaa aaatgataaa aatcttatgt caacactgat
      541 ttaggctgac ctgtgggtta ggagaaagac aggtcggtag cttttaatac aaaaaatggc
      601 ttgtatgtat ctagatagtt aactgaaatt agaaatgttc ttatttttaa cggagtaaga
      661 aaaataggct gctttaggtc tgaatacttt ttcaatataa tgaagatatc aaaggcgaca
      721 ggagtgtttt tatgaataag aatcctcata atctaaagtt ggtagcagta gatatggatg
      781 gaacatttgc tcgtactgat tacacatacg atatcccaag gttcaaggct gttttatcgc
      841 gaatgaaagc tgttgattgt caatttgttg ttgcaagtgg aaatcaatac taccaattga
      901 gatcgttatt tccaaattat tatgatgaat taagttttgt tgctgaaaat ggtgcttttg
      961 ttaaagataa aacagaggta ctattttcag ccgatatgcc tagaaaagcg atcgaggtgg
     1021 tccttgattt atgtaaagac tatcctgaag taaaaaatgt gatgtgtggt ctgaatagtg
     1081 cctactgtga aagaggaaag gtgagtcaag cattttttga tctaaccaat atctattacc
     1141 atagattaga atgggtagct gattttgcag aagttcaaga taaaatttta aaatttgctc
     1201 cgactatgcc tgttgaaaaa accgaatttt acgttgaatt gttccgtgaa aaattagccg
     1261 ggctattagt acctaccagt agtggtcatg gttctgtaga cttgattctt tctgagtgcc
     1321 ataaaacttt cggcttgaaa atgttagttg agcgcttggg gattaatcct gaccagtgcg
     1381 ttgcttttgg agatgggggc aatgacattg agatgttgga gtattgtggt ctgagttatg
     1441 aaatggataa tgcaacggaa gctgttaagc aagttgctaa gcatcaatgt ccttcaaatg
     1501 acgaagacgg tgttttagtg acgctcgatc gattgttccc taacacgtaa acactaggta
     1561 attcatcaaa aaacctcgat ataagaaata ttcgaggttt taaaactata tttagaacag
     1621 atttacgaag cgtctgatga gtcaaaatag acttggacat tgctatctaa aataccactt
     1681 tcattcttta aacgaattgt ttgatttgat ggagttacct ctaatactaa atgcccatta
     1741 ataaaggtag tatcgtattc agatgtttta actgttgctt cttcgcaagg tattgttaaa
     1801 tcatatgctg gaatataatg ttgtgtggaa actaataaaa aatgatcacc aatcatacag
     1861 catccctctg ctgaagaaaa ttgattagag ccatcattta aagttaacaa gaatccatcc
     1921 tttaaacgag gtacttgctt aaatacttct ggttgtactt ctaaaaataa attatcgctc
     1981 attttcacga ccaccatcga cttccacagt tgaaattgac attttattta acacacctat
     2041 tcccccttaa ctataactca attctatata aaaaatattc tattctcaaa taattgaact
     2101 tttcaaatcg ccaatttact tcggctttat cagagctcat tcatatcaag agcgattaac
     2161 gctgtaaaaa ttaaaccgaa gatctgataa attttctcta ttttctacaa tatttaaaac
     2221 gcttccttag tctattatat atctatttct cttaggagta tgtttagatg tttgaataat
     2281 agttgcccaa ctttaaaggt tattcttata atattttact tcattttcca atagaaaatt
     2341 caaaggatta ctggtttttc taaaatagtt tagtttaaat acataagtat cctccgacac
     2401 tgtattagtt cataatcatc taaatacaaa attttcaaat aaaaatattt caagctctat
     2461 cgttgacgaa tgtaaacgat acttataaag taatagaaat tgattacatt tgtaaactta
     2521 aaatggttaa tttatctcac ataaaactaa gaataaaata atgattaaaa gtggttagtt
     2581 tttatacgat ttagcctatc ggtaaaaatg aattagagag tgtaaaatat tttgtgtaaa
     2641 tgaaaaaatc catacaaaaa aggaagtc
//
LOCUS       DAFEKH010000134         2640 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.143, whole genome shotgun sequence.
ACCESSION   DAFEKH010000134
VERSION     DAFEKH010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2640
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.143"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            724..2550
                     /gene="ltrA"
                     /locus_tag="LP386_002930"
     CDS             724..2550
                     /gene="ltrA"
                     /locus_tag="LP386_002930"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBL1920096.1"
                     /translation="MLKKNKLRYNEYYDMQHIYDELYAQSKNGNNFYKLLEIIGSEQN
                     ICLAYRNLKSNSGSKTAGTDGMTIDDIKQLSNAEIVATVRESLSNYRPKSVRRVFIPK
                     AGSDKMRPLGIPCIWDRLVQQCILQVLEPICEPKFHNHSYGFRANRSAHHAVSRVTTL
                     INLSKYHYCVDVDIKGFFDNVNHGKLLKQIWTLGIRDKRLICIISKMLKAEIDGEGVP
                     EKGTPQGGLLSPLLSLIVLNELDWWVSSQWETFQPKNRSKNGWLQYAKKYTKLKSGFI
                     VRYADDFKIMCSTYGEAQRFYHSTVDFLNKRLKLEISPEKSKVVNLKKNSSDFLGFKI
                     KVIPKGRTKHGYVAKTDMNQKALKKAKTNLKLKVKDIARHTTGFNISRYNLTVIGMQN
                     YYCIATNVYNNLTEVSYALLPTIRIRLRNIAKSVPFESTSSEFQSRTKGIRPKTKIVM
                     IADNPLLPIQGVQHKNPMNFSQDICNFTKQGRNKVHEDVVVVTKEEIRALLENENPAD
                     SVEFNDNRISAYIAQQGNCYVMNRRGTPSTLICIHKSDKGDNLDRYSNLAFVEIPIAK
                     AILTESADEAKSLLKGYVLNSQQKKKLNRIRTNYGYQTITGK"
BASE COUNT          948 a          461 c          584 g          647 t
ORIGIN      
        1 aaaagagtag gcacagcact tcattaaatc aatatttaat gtgtgttgga gaactaaaca
       61 cacgaatagt cgaatgacgg ggtaacgccc tgaaaggcta ctttaatact ctgactggca
      121 gaaacttgag taaacaaggc tctgtcagaa gctcggtgaa gtcggcagac agacaccgta
      181 acagataatg ctgacgaaag attcccagag gtgggcgttg tgtcctatat gccggaagtc
      241 tataaaatat ctatggttag aatgtagatg agaggtctac tgacgaatcc ttgaatgtac
      301 aggtctatat cggggctgga tagaaatgtc cagtgacaca aacagtgtcg ctactgtggg
      361 tgagtaagac tccgcattta tgaaaatcca tataacgtta aaggcgttat caaggtagca
      421 ggcttataga ggaaacctaa ggatatatgt acagatagtg tgtttggaac gttgaaagct
      481 gacaacatgg agattttact gtctgtgaag tgttcacatc agaaagttat tgtgagatta
      541 gcaatgatat aaggtgtgtt aatgtcagtg agagtggtgg cacagtacct atgaaaccgt
      601 gataacaagc ggtggaggga tagccactag tcatatgaag aatagaatta ctaagaaaaa
      661 tggtatgggt tcgagtaaga ctaagagatg tacttgctcc tgcaaacaag gagggtacag
      721 accatgctaa agaaaaacaa gctccgctat aacgagtatt atgatatgca acatatttat
      781 gacgagttat acgcacagag caagaacggt aataactttt ataagttact tgaaattatt
      841 ggttcggaac aaaatatttg tttagcttac cgtaatctga aatcaaacag tggcagtaaa
      901 acggctggaa cggatggaat gacgatagac gatataaaac aactcagcaa tgctgagatt
      961 gttgctaccg ttcgggaaag ccttagcaac taccgcccca aatcagtcag acgtgttttc
     1021 attccaaaag ctgggagcga taaaatgcgt ccattgggga ttccgtgtat ctgggacagg
     1081 ctggtacaac aatgtatcct gcaagtccta gagccgatat gcgaaccaaa gttccataat
     1141 cattcctatg gattccgtgc gaatcgaagt gcccaccatg cagtcagcag agtaacgaca
     1201 ctgataaatt tatcaaaata tcattactgt gttgacgtag acattaaagg atttttcgat
     1261 aatgtcaatc atggaaaact attaaaacaa atctggacac ttggtattcg ggataaaaga
     1321 ttgatttgca ttatcagcaa aatgctgaaa gccgaaattg acggcgaggg tgtcccagaa
     1381 aaaggaacgc cacaaggcgg tctgttaagt ccactgctct ccctcatagt ccttaatgaa
     1441 ttagactggt gggtaagcag tcagtgggaa acattccagc cgaagaaccg cagtaaaaat
     1501 gggtggcttc aatacgcaaa gaaatatacc aaactgaaaa gcggttttat tgtacgttac
     1561 gctgatgatt ttaaaatcat gtgttcaacc tatggagaag cacaaagatt ttaccacagt
     1621 accgtagatt ttcttaataa aaggctgaaa ttagaaatca gtccagagaa atcaaaggta
     1681 gtaaatctga agaaaaattc atcagatttt ctggggttca aaatcaaagt cattccaaaa
     1741 ggaagaacga aacacggtta tgttgccaaa acagatatga accaaaaagc attaaagaaa
     1801 gcgaaaacaa atctaaagtt aaaggtaaaa gatatagcca gacatacgac tggcttcaat
     1861 atcagcagat ataatctgac agttatcggt atgcagaatt actactgcat agcaactaac
     1921 gtatataaca acctgacaga agtaagttac gctctcttac cgaccatacg aatccgttta
     1981 aggaacattg caaaatcagt tccatttgaa agtacaagtt cagaatttca gagcaggaca
     2041 aaaggaatca gaccaaaaac aaaaatagtg atgattgcgg ataatccgct attgccgatt
     2101 caaggagtac aacacaaaaa tcctatgaat ttctcgcaag atatttgtaa ttttacaaag
     2161 caagggagaa acaaggtgca tgaggacgtt gtagttgtaa caaaagaaga aatccgagcg
     2221 ttgttggaaa atgaaaaccc tgccgatagc gtagagttta acgacaatcg tatttcggca
     2281 tatatcgcac aacaaggcaa ctgctatgta atgaatcgtc gaggaactcc gtccactctg
     2341 atatgtattc acaaatcaga caaaggagat aaccttgaca gatattctaa tctggcattt
     2401 gtggaaattc ccattgcaaa ggcaatccta acagaatcag cagacgaagc aaaatcactg
     2461 ttaaaaggtt atgttcttaa tagtcagcag aagaaaaaac tgaacagaat acggacgaat
     2521 tacggatacc agacaataac tgggaaataa cttataaatc tatttggata tgatggaacg
     2581 ccgtatgaag cgaaagtttc atgtacggtg tgaagcgggg gaaaacttgg agataacatc
//
LOCUS       DAFEKH010000135         2640 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.144, whole genome shotgun sequence.
ACCESSION   DAFEKH010000135
VERSION     DAFEKH010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2640
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.144"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            693..2555
                     /gene="ltrA"
                     /locus_tag="LP386_002931"
     CDS             693..2555
                     /gene="ltrA"
                     /locus_tag="LP386_002931"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBL1920097.1"
                     /translation="MENVSASHSIRHMEYYGMIDSFDNLYKESSDNHVFNNLMEIVTS
                     SNNILLAYRNVKGNSGSVSPGVDNKNIDDLKEIPNADFIKIVQTKFSEYKPQPVKRVE
                     IPKPNGKTRPLGIPTIWDRIVQQCLLQVLEPIMEAKFHDKNYGFRPNRSAHHAFAQAV
                     RLAQVSKLTFVVDIDIEGFFDNVNHSKLIKQLWTLGVQDKWLLGVIRAMLKAPIIHKD
                     GRIEHPKKGTPQGGILSPLLANVVLNELDWWISSQWETHPTRHNYDWYHAEKGYWNKG
                     NKYRALRGSKLKEIYIVRYADDFKIFCRKRSDADNIFIAAKSWLKERLKLDISIEKSK
                     VVNLKKQKSEFLGFTMKLVRKRKTFVIETHMCHKAMKKVSDNLAKQIKVIQHTPTKEE
                     LQKQLVKYNSMVIGIHQYYKKATHISVDCPKINQRIMIIIKNRLDVKKNGHPPSDFVK
                     KNYACSKQLRWINGYPMIPLGFVKHSHTSLPKMGICKYTPEGRVLIHKYLTFPIDIIN
                     QLMNMNNPDESIEFRDNRVSKYSSQRGRCRVTKEFLELADIYCHRIIPKNLGGKDNFQ
                     NLVIIHRNIHQLIHENDKARATLLVMEMRITGTQLEIINQFRKKAKNCELSLNL"
BASE COUNT          918 a          492 c          559 g          671 t
ORIGIN      
        1 aaaaggttag gcacacaagt tcttcttgtg gagaactgat gatttgagga gtgaaatgat
       61 ggcgtaacgt cctgaagcgc tccctctgat actccgattg gcaattctct tggtcagaat
      121 aagaattgtc aagagctcgg taaagtcggc tgagagttac cgcagttgca ttgctgcaat
      181 cgaaagctgt ccagcggtgg atagtgtaac ctataggccg ggagtccaaa aattactcat
      241 ggtgagaatg tgcaattgca ctgacaaact tgcgaatgta cgaatctata ggcttggggt
      301 gcagaaatgt atcttgtccg cacaaaatct atattgtgac acagggtgcg acttgcggtt
      361 tagtaagaat cgtagatatg aataaccgtg cagtgttata ggcactggaa agtcgcaggt
      421 tcagagtgag cacctaaaag taaatgtatg gataaaatca ttggaacgtt gaaagctagt
      481 gacgtggagg actaacctcc tttgaagcgg ttgagacgaa gaataataag ctcattcaca
      541 ctagtgagag tagtggcaca gtacctatga agcagtgata acaagctgtg gagggatagc
      601 cacgagtcaa ttagttttac taacagttat gatgcaatcc atagaatcga gtatgacaaa
      661 ataaacaccg acatccgaag ggaggcggtg ctatggaaaa cgtatcagca tcacactcaa
      721 tccgccatat ggaatactat ggcatgattg acagctttga caatctatac aaagaaagta
      781 gcgataatca cgttttcaat aaccttatgg aaattgtaac ttcgtcgaat aatatcttat
      841 tagcgtatag aaatgttaaa ggaaactctg ggagcgtatc tccaggcgtt gataacaaga
      901 atattgatga tttaaaagaa atacctaatg cggattttat caaaatcgtg caaaccaaat
      961 tttcagaata caaaccacaa ccagttaaaa gagtagaaat cccaaaacca aacgggaaaa
     1021 ctcgtccact tggtatccca actatctggg acagaatcgt acaacaatgt ctattacaag
     1081 tcttagaacc tatcatggaa gcaaaattcc atgataagaa ttatggtttc cgacctaatc
     1141 gatcggcgca ccatgcgttc gctcaagcag tacgattagc acaagtgtct aaacttactt
     1201 ttgtagtaga tatagatatt gagggattct ttgacaacgt aaaccattca aagcttatca
     1261 aacagctctg gacattagga gttcaagata agtggctttt aggtgttatt agggcaatgc
     1321 ttaaagcacc tatcatccat aaggatggcc gaattgagca ccctaagaaa ggaactccgc
     1381 aaggcggaat actttcccca ctcctcgcaa acgttgtgct aaatgaacta gactggtgga
     1441 tatcatcaca gtgggaaacc caccctacaa ggcataatta tgattggtat catgccgaga
     1501 aaggttactg gaacaaagga aataaatatc gagcgttgcg tggttcgaaa ctaaaagaga
     1561 tttatatcgt aagatatgcc gacgacttta aaatcttttg cagaaaacgt agcgatgcag
     1621 acaatatatt tatagccgcc aaatcgtggc taaaggaacg gctgaaactc gatattagca
     1681 tagaaaaatc taaagtggtt aatctgaaaa aacagaaatc cgagtttctc ggttttacta
     1741 tgaaattggt tcgcaaaaga aaaacctttg tcatagaaac gcacatgtgc cataaagcta
     1801 tgaaaaaagt atctgataat ctagcaaaac aaataaaggt aattcaacac acccccacca
     1861 aagaagagtt acaaaagcag ctagttaaat acaactcgat ggtgataggg attcatcaat
     1921 attacaaaaa ggctacccac atcagtgtgg actgtccgaa aattaatcag cgtataatga
     1981 ttatcattaa aaatcgattg gacgttaaga aaaatggaca cccgcctagt gatttcgtta
     2041 agaaaaacta tgcatgttca aagcagttaa gatggattaa tggctatcct atgattcctt
     2101 taggattcgt caaacacagc catacgtcat tacccaaaat gggaatctgc aagtacacgc
     2161 ccgaaggacg tgtgctaata cacaagtatc ttacctttcc aattgatatt atcaaccaac
     2221 ttatgaatat gaataaccct gacgaaagta ttgaatttag ggataatcgt gtctctaagt
     2281 actcttcaca acgaggcaga tgccgagtaa caaaagagtt cttggagcta gcagatattt
     2341 actgtcaccg tatcatacct aaaaatcttg gtggaaaaga taacttccaa aatttagtta
     2401 tcattcatcg gaacattcat caacttattc atgagaacga taaagcgaga gccacactcc
     2461 ttgtaatgga aatgaggatt acaggcactc aacttgagat aatcaaccag ttccgaaaaa
     2521 aagctaaaaa ttgtgaattg tcgctgaatc tataactgta tgatacctgt tagtagacat
     2581 tgatggaacg ccgtatgcgg cgaaagtcgc acgtacggtg tggagcgggg gaaaatctgg
//
LOCUS       DAFEKH010000136         2633 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.145, whole genome shotgun sequence.
ACCESSION   DAFEKH010000136
VERSION     DAFEKH010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2633
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.145"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            5..1149
                     /locus_tag="LP386_002932"
                     /pseudo
     CDS             5..1149
                     /locus_tag="LP386_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
     gene            1320..1778
                     /locus_tag="LP386_002933"
     CDS             1320..1778
                     /locus_tag="LP386_002933"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HBL1920098.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            1937..2407
                     /locus_tag="LP386_002934"
     CDS             1937..2407
                     /locus_tag="LP386_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HBL1920099.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(2460..2575)
                     /gene="rrf"
                     /locus_tag="LP386_002935"
     rRNA            complement(2460..2575)
                     /gene="rrf"
                     /locus_tag="LP386_002935"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          863 a          504 c          496 g          770 t
ORIGIN      
        1 aaacatgcac attcaaacaa aattgatcca cggaggcatc agtgaagatc ccacaacagg
       61 agctgtcagt gtacctattt atcaaacatc cacttatcgg caagatggcg tcggccagcc
      121 taaacaatat gaatattcaa gatctggtaa tcctactcgt tttgcattgg aagaactgat
      181 tgctgatttg gaaggcggtg ttcgaggatt cgctttttct tctggtcttt ctgggattca
      241 tgccgttttt tctctttttc aagctggcga tcatatctta ttaggagatg atgtctatgg
      301 aggaacattc cgtctatttg acaaagttct tactaaaaat ggtctcgagt acacgatcat
      361 agatacgagt aatcttgata aaatagaaca atccatcaaa cccaatacaa aagcacttta
      421 tcttgaaaca cctagcaatc cgcttctaaa gattactgat ttagaaaaaa gtgccactct
      481 ggctcatcaa catggattga tagttattgc tgacaataca tttgctactc cttattttca
      541 aagaccttta gatctcggtt ctgatatcgt tgtccatagc ggtaccaaat atctaggcgg
      601 acacagcgat gtagtagctg gtttagtgac ttctaaccaa aagatctagc cgatcagatc
      661 ggattttacc aaaatgctat cggagccgta cttggtcccc aagatagctg gttacttcag
      721 cgcggaatca agacactaag tgttcgtatg gaggaacatc aaaaaaatgc ttttgtggta
      781 gctgattttc tattttctca tccagcagta gaaaaggtct actatccagg attacccgat
      841 catgaactcc atggagttgc taagcagcag atgagcggct ttagcggaat gatttctttt
      901 actttaaaaa atgaagaatc tgctattcca tttgttgaat cactccaact atttacttta
      961 gcagaaagtt taggtggcgt agaaagttta gtggaaattc cttctgtcat gactcatgcg
     1021 tctattccaa aagaaaaacg agaagaggct ggcataaagg acggcttgat ccgtctttct
     1081 gtaggaattg agtatggtca ggatctcata aacgatttag ctcaggcatt tgacagaatc
     1141 aagaactaga agtcccaata aacgacttag cagaaaaatc taaaaaatat ttcagattgc
     1201 tacaccttgg aaacgataag tgttagaatc aagtagaaag acgtttttgt aaatttcact
     1261 aaataattct ttagtgaaaa gcatcaaaac gaatgaacaa acagatagga gtcttacaaa
     1321 tgagaatgaa tgtcgaaagt tttaatcttg accatacaaa agtcaaagca ccttatgtac
     1381 gtgtagctga tcgaaaaacg ggtgcgcatg gcgatgtcat cattaaatac gacgtccgct
     1441 ttaaacaacc aaataaagaa cacatggaca tgccaagtct acattcactt gagcacttga
     1501 ctgccgaact aatccgcaat cacgcagatt acatcgtaga ctggtctcca atgggatgcc
     1561 aaacaggctt ttacttgact gtattgaatc atgaaagcta cgaagacatt ttagatgttc
     1621 ttgaagcaac aatgaaagat gttcttgaag ctactgaagt acctgcaagc aatgaaacac
     1681 aatgtggctg ggctgccagc catacactag aaggtgcaca agctttggct cgtgaatttt
     1741 tagcaaaacg cgatgaatgg tctgaagtag aagcatagtt tctaaaagaa cgtaaagatg
     1801 agaagcaata tagctatctt atcttcgtat tttattaaat atttattgtc tgaaaagagt
     1861 tctaaacggg aaaacaaata gctagttttc agtttagcgc tctttttatt atataaaata
     1921 gaaaggagaa aactttatgt ctatttataa ttttgaaact actttagaag acggcactgt
     1981 ctattcattg aaaaaatatg caggcaaacc gataatcatt gttaacactg caacaaaatg
     2041 cggtctagca cctcaattta aacaattaga agaactttac caagcttatc agacacaagg
     2101 tctggttatc ttaggctttc cttccaatca atttaaacaa gagctagatt cagcgactga
     2161 agcagcagaa gcttgtaaaa ccacttatgg cgttaccttc cctatgcatc aattgattga
     2221 cgtaaatgga gaaaatacag atcctctttt tacttatctt aaaaatgaag ctcctggtac
     2281 tgtcactaaa gcaataaaat ggaattttac taaatttttg attgatagaa atggcaaagt
     2341 aatcgaacga tttgcaccac aaacttctcc attgaaaatg accgctgcaa ttgaatccgt
     2401 tctttaactt aataaaaata aaaaaagatg aactatttct agttcatctt tttgcctttg
     2461 cgtggcgacg tcctactctc acaaggggca acccctcact acaatcggcg ctaagaagct
     2521 taacttctgt gttcggcatg gttacaggtg tatccttctc gctatcgcca ccacactgtg
     2581 gtgttatctt ttattgagta aattttgttc actcaaaact ggatttgaag tca
//
LOCUS       DAFEKH010000137         2505 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.147, whole genome shotgun sequence.
ACCESSION   DAFEKH010000137
VERSION     DAFEKH010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2505
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.147"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            345..1925
                     /locus_tag="LP386_002936"
     CDS             345..1925
                     /locus_tag="LP386_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HBL1920100.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            2123..2347
                     /locus_tag="LP386_002937"
     CDS             2123..2347
                     /locus_tag="LP386_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HBL1920101.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
BASE COUNT          892 a          404 c          530 g          679 t
ORIGIN      
        1 cttttagtca gctgacaaaa aaatatttga ctcttatggt ttggtggctt tttcattcgc
       61 tgaatccatg ctatactgat tcagttgtag tagttgacaa aggttgtgaa aaagctatcc
      121 tgcattaagt aataagagca gccaagcaaa aacagctttt cgtatttttg gcttgggtgg
      181 gcttattgct gataggctgt ctctagaacg ccgtttactc ggaaaaagag actgctacac
      241 ggcttttgtc acagccctat atgaaattgt ctttctttaa gagatcggac aatctgtgcc
      301 tagagaaaat ataaataatt gaatggaaga aatggagtta ggttatgaat aatccaaaat
      361 taaagcaaca agtggacaat cgcagaactt ttgcgatcat ttcccatccg gatgctggga
      421 aaacaacgat tacagaacaa ttactattgt ttggtggggc tatccgtcaa gccgggaccg
      481 taaaaggcaa aaaaacaggt aattttgcca aatcagactg gatggaaatc gagaaacaac
      541 gtgggatttc tgttactagt tctgttatgc agtttgatta tcaagggaaa cgagtaaata
      601 tcttggatac accaggacat gaagattttt ctgaagatac ttatcgtact ttgatggccg
      661 tggatagtgc ggtcatggta atcgatagtg caaaagggat cgaagcacag acaaagaaat
      721 tattccaagt tgtaaaaaaa cgtggcatcc cgatatttac ttttatcaac aaactagatc
      781 gtgatggtcg tgaaccattg gaattgttag aagaattaga agagctatta gatatcgaat
      841 cttatccgat gaattggcca atcggtatgg gtaaagggct agaaggtctt tatgatatct
      901 accataatcg tgtagagttt tatcgtccgg aaaattatca ggatgaacga ttagtagaat
      961 tggatgaaga tggactgctt cccgaaaatc atcctctaac tgaaaattcc ttatatgaac
     1021 aagtcttaga agaagtagaa ctaatcaaag aggctggaga tgcatttaat caagaaaaaa
     1081 ttgctcgtgg cgatcagaca ccagtatttt ttggttctgc attgactaac ttcggtgtac
     1141 agactttttt agagactttc gttgaattgg caccagctcc ttatggacac aaaacacaag
     1201 atgatcagat ggtaagtcct tatgaggaag aattttcagg tttcgtattc aagatccaag
     1261 caaatatgaa tccagcccat cgtgaccgaa tcgcttttgt ccgaatctgt tctggaacat
     1321 tcgaacgagg aatggatgtc tggttggaac gtacaaataa aaaactgaaa ttaagcaatg
     1381 tcacacaatt tatggcagat tcgagagaaa acgtcgaaaa agcagtagca ggcgatatca
     1441 tcggtgtata tgatacaggc aattatcaga ttggggatac attgttcgaa ggaaaactaa
     1501 aagttgctta tgaagaactc ccttcattta ctccagagct gtttatgaaa gtgactgcaa
     1561 aaaatgtcat gaaacaaaaa tccttccaca aaggaatcta tcaattagtt caagaaggag
     1621 cgattcagct ttataaaaca tatctaacgg aagaatatat cattggagct gttggtcagc
     1681 tacaattcga agtattccaa tatcgtatgt taaatgagta taacgccgaa gtaatcatgt
     1741 ctccaatggg acacaaaatc gctcgctgga tcgatccaga agatttggat gagaagatga
     1801 gttcaagtcg caatatcttg gctcgtgacc gtttcgacca accgttgttc ttattcgaga
     1861 accaatttgc agaacgctgg tttgcggata aatatcccaa tgtaaaatta aaaagtttga
     1921 tgtaaagaag tcttgacaca agctgccctg catcaagtaa taagaatagc caaacaaaaa
     1981 cagcctctca tattttgttt agagccgtga cggattttcc gtgacggctc tttttactat
     2041 attaaaatca tagaaatgtc taatcaaaaa aatataaaaa ttattttgcg tacatatgat
     2101 taaagaaagg agagtgtgac acatggaaac agaatggcaa agacgtgaaa gaaaaaaaca
     2161 gaaaaaagaa gagatgttac gattatgtcg attattagat gtaaaagact gggacaaaaa
     2221 cgagcaaatt gcacaaaaag tacgatcaat catccataaa gaggaaaaag ttaaaaataa
     2281 agacacgcgt agaactgaaa atgaaaagag aaaagtacaa aagaaaagag aaaaatcaaa
     2341 aagctagaaa gaaaaagagg ctgagacaga agcgtttaac tccaagaaat aagctggaat
     2401 tcacaaaaat ttgaaaagca attttcgtga atttcagctt atttccgaag gagttgcttc
     2461 tgctttcgcc gtttatacgt gtttagagcg tgagacaaaa gtgtt
//
LOCUS       DAFEKH010000138         2421 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.148, whole genome shotgun sequence.
ACCESSION   DAFEKH010000138
VERSION     DAFEKH010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2421
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.148"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..171
                     /locus_tag="LP386_002938"
     CDS             <1..171
                     /locus_tag="LP386_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HBL1920102.1"
                     /translation="SLFPLYHGSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFK
                     IEYTKKRQRLAY"
     gene            406..642
                     /locus_tag="LP386_002939"
     CDS             406..642
                     /locus_tag="LP386_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920103.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            649..>2421
                     /locus_tag="LP386_002940"
     CDS             649..>2421
                     /locus_tag="LP386_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HBL1920104.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTVNGGIKM"
BASE COUNT          892 a          367 c          475 g          687 t
ORIGIN      
        1 tctctgttcc ctctttatca tggaagtgca aaaagtaata tagggattga taaccttata
       61 gaagttatta ctaataaatt ttattcatca acacatcgag gtccgtctga actttgcgga
      121 aatgttttca aaattgaata tacaaaaaaa agacaacgtc ttgcatatta agtagttcag
      181 ttttggagta caaaaagtga aaatgtaaac ctaaatgagt atcaaattgc aactgaattt
      241 gatactcgtt ttttattgtt aaatcaacgt ttgttgttaa tttacaccac aaaatgtaag
      301 ttaaaatgta tataaaaatg cgaacgtgaa ataattattg taggaatgca aattggtgtg
      361 ttaaaatggt tacaatttac taagcaaaaa ggggtgcatt ttcctatgca atttcttgag
      421 ccaaaaaata agaacgctaa gtctgtggat tgggaaatat cagagcaagt aagggtgata
      481 gttaagcaat acgctgaata tgcagagcgt actgaaagcg aagcagtgga tgaattctta
      541 ttgaacattt tagacgataa gaagtttatt gaatggattg ccaacaagcg aagtaataag
      601 cggattgttg aaaaaatggg tatcaaagat agagtgggtt gatagacaat gaccaagctt
      661 aaaagattag ccacgaagga agatgaaatt gtagatgtta aaattccgat ttcaaacgaa
      721 gaattaaaag atagggctaa acaatatgat ttattaactc caaaacgatt tgcaacaagg
      781 tataacaaaa tgttgttctt gccaacgtct tttaaatgga acggttctga atatcccatt
      841 caatataatt actgcatcaa tccgttttgt tgtaattttg ggaaagaaca gcacaaattc
      901 aaagatgtaa aagggaaacc aagtcgatat aaaatgactg gtagttccaa agataaaggt
      961 cataaaggta tgtactgcaa tgacaatcct attggcagag gtgtatcgca aaactgtaca
     1021 gtaacccctt tatctaattg gtctgttgtt gaagaaatta aacgccttat agaaatcaat
     1081 agcatccaag atgttgagcc agattatcaa tttcataaag aaggctgctc ggaagaagaa
     1141 tcaaccccat tcaatgagcc gaagcaattt tacaaaaggg ggaaaagtag gggcaaatct
     1201 caacgctatc aatgtaaggc gtgtaagaag ttcactaatg ttctaccaaa aagagaagaa
     1261 accactactt atcaccaaca aaagaacacc attcttccaa tgttcgctaa gatggttgtt
     1321 ggaagggttt cagtcagtcg tacttgtgat attttaggaa ttggagttgg aacctactat
     1381 cataagctgg agtggctgta taggcgttgt ttggagtttt tagaacgata tgagacacaa
     1441 ccccttcaaa caaagaaatt taacgagatg tggcttaata cggacaagat gcactactac
     1501 ctaaataacg tccgtaagaa aggacaaggt tcaaagaaat atacggggtt tgaagacctt
     1561 aatatgcaaa cgtatatagt tgtatctgct gaggtcttat caagatatgt gttccgttct
     1621 gatgttgcct atgattggaa tatttcaatg gatgaattaa atgaagatac aagaaaattc
     1681 aaagaagacc atctcaatac ttttagtcgt aaaaatgata ggttagattg gtcttattat
     1741 ccacaagaac catccgctaa cgatagcgaa aataggaatg cttatcttca cgaattaggg
     1801 aaaattacta ataggagtag atttgtcgat ggtttaaatg ttgatgctcc ttatactaca
     1861 actgctcact attggttaat taaacaaatg gttaatgccg acgaatggcg aatgattagt
     1921 gatgatgact tctctattag aaacgccttt tatagagtat tcacgaaaga attaaggttg
     1981 agcgatgcac atcattttat ttgccaagtt aacaagacga aaagcagaaa acaatgctta
     2041 aaagaattcg gacaagcaaa agcagaactg ctcgattggg gagatatcag aggattcaaa
     2101 acaaagtttc tacggacttt ggcatctcat tatctaactg aattactaac aagtcatcaa
     2161 ttccacgaag aggctattag taaagatgga gaaagatatc gcaaatatgc cgataaccct
     2221 atcaaacatc cattagccac taaggataaa ggattttatt cagttgattg tagaacggat
     2281 ttatctgctc tggaaccaaa cgaaatcgca aagatgctat taaatgttaa tgaccattcg
     2341 accaatagct ttattcaaca gataagacgt tatatatcat ctcttgaaag accattaact
     2401 gtcaatggcg gaataaaaat g
//
LOCUS       DAFEKH010000139         2399 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.149, whole genome shotgun sequence.
ACCESSION   DAFEKH010000139
VERSION     DAFEKH010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2399
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.149"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            206..2068
                     /locus_tag="LP386_002941"
     CDS             206..2068
                     /locus_tag="LP386_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL1920105.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2068..>2399
                     /locus_tag="LP386_002942"
     CDS             2068..>2399
                     /locus_tag="LP386_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL1920106.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          865 a          353 c          466 g          715 t
ORIGIN      
        1 aaaatttgaa aaagcgtttg attatttata ttacgactta gtgcaataaa aaacgctttt
       61 taacagtaca tgtagtcgtc tttataatag ataaactctg taatattagt taaaaagcta
      121 taagttgcac ttagttaagt gcaaacattt catattgtcg ttagtttaga aaacgcttat
      181 attagcaatg taaggagaga tgataatgca gcagctaaca aaaagagaaa ggcagctttt
      241 gatttacttg gtggaaatgt ctgaaccggt aacaatcaaa aagttggctg aaaaagaaaa
      301 tgttagtgtt cggacgataa aatacgatct agatgatata agagagtggc tgaatgagcg
      361 gaagcaagtc ctatatagca aacgtagtca gggaatttgg atgaatatta gtagctctga
      421 tcgaatcaaa ttaaaaagcg aattgatgga tgttaatcgt tttgaaatat ttgcagatca
      481 aagtctccga atcaaacgtt tactaattat gcttttagta acaaaagaag ctattactgg
      541 aatgaaaatg gccaacgcat tagatgtcag caaagatacg atcatgaatg atttagatgt
      601 gctggaaaat aattttctta aggaaggatt gaccttgaat cgtcaggcgc gaaagggttt
      661 ttggatcata ggagaagaac gtctagttcg attaacgatt gaagagattc ttcaaaaaga
      721 gttcacggat tatgacattt ataaattaat gtcattgtta ttgaatggcg gtgagactga
      781 atactttgaa atgtattctg ctactgctac acctatccaa gaggtattta atcaagtaat
      841 cattcgaatg cgacacttac tggaatttga aaatctagag aaactgaatt acgcggaatt
      901 actaaatatt ctgattcgag tgacaattgc taccgttcgc ttacgcaaag aggctacgat
      961 tggtcgttat caattggttg ctgaacaaga attagacaaa aacgatcttt cttatcgcgt
     1021 catgcagcag gtctttgatt attatcagtt gccactgttc gaggatgaat atcattatat
     1081 ctatagtgat acattcgaca cgattcacca gcaagacgtc atgaaactag ttgagaatgt
     1141 gatttataaa gtaagtaaag caatcaacca ttctttttat caagatccac aattgttgac
     1201 gaatctgtat gctcatttat ccatgcgatt atcgagaaag aaaaaatttg tcaatgaata
     1261 taatcctttt aaagaagata tcaagcagaa atacccggaa ttatttgatg cgatcaagca
     1321 agcagttcga caagaaataa gtgaacaaaa tattctgatc aatgattctt tcgtggcata
     1381 tattgcctta cactttttgg tttcctacga aagagaagaa gatctacgaa gcgttagagc
     1441 cgtctacatt tgttcaacag ggttgggtgt gactagtctg atcaagcaaa agatcaatga
     1501 agaattaaat aatatcacta tcgtggcatt tgcttcagta ttgaatgcgc aagaaatgat
     1561 tgctaccaaa gatcctgatt tggtgattag tatttttcca attaatggca tcgatcgtcc
     1621 tttcatcaaa gtccatccat tacccactga acaggacttg aaaaaaattc aacaaataat
     1681 aaaaaaaata cttgcttctt ccaatcagca ggaaaggcat aacttgaatc ttagagaaac
     1741 gtccatcaat aaagatactt tagaagactt tagcaaggaa ttgattttga aagcttatac
     1801 gatttatgaa cgtttacttg tcattttgga agcagaattg atccaagaat atcgagaagc
     1861 ttttttgctt catgtattct taatggttca tcgtatcaca tttgatcaac aatatatggc
     1921 agaaggtcgt caagtagacc agattatttt agacaaagga acactggtag gaaaaatcga
     1981 agcagttttt gcagaaaata atttaggaat caatcagtca gaaatcagtg cattattctc
     2041 atatataaaa gaaggagcgt caagttagtg aaaatgtcag acgaggcttt aaaaattatc
     2101 gaggaaagtc aaaatcggga aaagttaaaa caagtgattg atctaattga agagcgatta
     2161 gtagaacatg ctattgtacc aaccgagttg cagtggacca ttctaattaa tcacttgaat
     2221 gagatgctga aacgttctca aagaaaggaa acgattcccg tagtcgatcg ggatttgttc
     2281 aaagaagtat ccaaagaagc cataactatt tctgatgaaa tagttagaag tatcggtaat
     2341 ttaaccgatg atgaaatata tgttttgtcg attcattttg aaacagcaaa aaataatta
//
LOCUS       DAFEKH010000140         2296 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.150, whole genome shotgun sequence.
ACCESSION   DAFEKH010000140
VERSION     DAFEKH010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2296
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.150"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..1233)
                     /locus_tag="LP386_002943"
     CDS             complement(<1..1233)
                     /locus_tag="LP386_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBL1920107.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQINEEN
                     LDKIIDKIRQKYGFTSIVH"
     gene            1683..>2296
                     /locus_tag="LP386_002944"
     CDS             1683..>2296
                     /locus_tag="LP386_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1920108.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
BASE COUNT          715 a          445 c          387 g          749 t
ORIGIN      
        1 atgtacaatc gacgtaaaac catatttttg ccgaatcttg tcaataattt tatctaaatt
       61 ttcttcgtta atttgctttt gtggatcact aaataaatcc agctgaagcg aatcggtgta
      121 cacaagcttg ctataggtta ttccaacatg ccttacttct tgtccttcat aatacttatc
      181 aaacaagaaa agacaataat tctgcaattc ctttgtatta tctgtgatag ggatcttcat
      241 ctggtgtgaa aaccctggtc tcgtttctaa gatcgacgtg ccaatgtgta aatggacaca
      301 acctgtttta cagttatgct gcctaatgcg tatcgctact tgttccgcca tttcttttac
      361 caccagctcg atttcatttc ttctagtata atctcgtggt aacacttgtg aatttccata
      421 tgatttttcc tttgtcggtt ctggtgggat tgctatatct gttcgatcga ttccgttagc
      481 atggaagtac agctgtaagc caatcacacc tagtctattc ttaatcgtat aaggattcca
      541 gttagcaaga tctctaatgc tcataatccc catctgattg agtctttttt tcattcgaga
      601 gccaattccc caaaagtccg tcatttcagg aatattccat actttttcag gaacgttttc
      661 gtacgtccat tccgcaacaa atccttcatt atgctttgct tcgttgtcta aggctagttt
      721 agccaaaagg ggattatctc cgacacctac tgtagcaatc aatcctagct cttctttaat
      781 attctcctgg atcatttgag ccagcttctt tctccgttga cttcgtgttc cttcagtcgt
      841 aaaaagattc agtgatcggg tcacttttaa gattgattca tcgatcgagt aaatcagtag
      901 atcttcatca gccacatatc ttctgaaaat attatttacc tgcatatttc gcttgatata
      961 taggttcata cgtggtggaa caacgtgtag tgttttagga aatggttgtg gtaagtcacg
     1021 tggtctactc acatttgtaa taccataccg cttttttgct tcaggagaag aagctaatat
     1081 caatcctgaa ccagtattat cagctcgact cataacaaca agttctgttg ttaatggatc
     1141 taaatttctt tctatacatt cgacacttgc gtaaaagctt ttcatatcga ttaaaaagta
     1201 atcatttact ggctcttttg aataatccat cataaataac actccattct ttcacattat
     1261 acaaacatat gttcgatatt gtaaagaaga aatagctaaa tacataaaaa aagaagcata
     1321 ggtatgctat caccctgctt cttcttttga tttgtatgat caatttattc tatcacttta
     1381 ctaattaatt tgaaaatcta ataaaaactc tcactctaaa agagtgagag actgcaaatt
     1441 agagtacgga cttttttgga gttccgttct ttaatattaa caaatgaata aaatccttac
     1501 aacatttgag aataagttat cagtagacac ttacaaaaaa ttctcatact atttcctcca
     1561 tcattagttt ttgtctatat aaggtatacc ctaactagac acgaccgcga cattgaaaaa
     1621 tctggttttc tcgtgtatga ttagggtgtt ttttaaatag ttgcagaaag taggtaaaaa
     1681 ttttgagagt tgcatacata cgtgtctcat ccatcgatca aaatgaacaa cggcagattg
     1741 aagaaatgaa aaaattcggt gcagagagaa ttttcattga gaaacaatct ggcgcaacga
     1801 ttactcatcg acctgttttt caagaagcac tggatttcgt ccgagatcaa gatattttta
     1861 ttgtggaagc tattgatcga cttggaagaa attacgacga gatcatcgct tcagtcaatt
     1921 acttgaagaa gaaaaatgtg cagctgatca tcacaagtct accgatcatg gccgaagcaa
     1981 ttggcaatcc tctcctggat aaattcatta aagatttgat cattcaaatt ttggccatga
     2041 tcgctgaaca agaacgtacc gaatctaaac gacgtcaggc acaaggcatt aagattgcaa
     2101 aagcgaacgg tgtttataaa ggacgtccta agctatacag tgccaatgca aaagatcccc
     2161 aacgtcgtct tgtttataaa aacatcgttg aggatctaaa aaaaggtgtt gcgatcgcta
     2221 agattgcaaa agactacaat gttacgagac aaaccgtata tagaataaaa aaagacagca
     2281 tggtcaatca cgaata
//
LOCUS       DAFEKH010000141         2195 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.151, whole genome shotgun sequence.
ACCESSION   DAFEKH010000141
VERSION     DAFEKH010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2195
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.151"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     misc_feature    110..235
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            279..803
                     /gene="infC"
                     /locus_tag="LP386_002945"
     CDS             279..803
                     /gene="infC"
                     /locus_tag="LP386_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HBL1920109.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            875..1075
                     /gene="rpmI"
                     /locus_tag="LP386_002946"
     CDS             875..1075
                     /gene="rpmI"
                     /locus_tag="LP386_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HBL1920110.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            1128..1487
                     /gene="rplT"
                     /locus_tag="LP386_002947"
     CDS             1128..1487
                     /gene="rplT"
                     /locus_tag="LP386_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HBL1920111.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            1839..>2195
                     /locus_tag="LP386_002948"
     CDS             1839..>2195
                     /locus_tag="LP386_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HBL1920112.1"
                     /translation="MATVWMGLALVGNTFSPNSAMEGQGVIDVLTHIYTTGPAEYAKS
                     ILVNVFFGAFFGRVLVDSGIAATLIRKVVELGGDKPRITMSLLCIVTAVIFMSMTGIG
                     PVISIAVIVLPILMSLG"
BASE COUNT          735 a          384 c          479 g          597 t
ORIGIN      
        1 aattcactgc tagaaagcct gctaatctaa tcattttcag aaaaggaaga caaactgtat
       61 gaaaaacatt gacaaaaaga ttagtttttg ctatactata atggttgaga aataaaagca
      121 gaagcacccg cttctcgcct tagttgataa tgtcactggg ctagatagtt ttcactggtt
      181 ctattaggtg aagtacgcgc gggttctgta agagaactcg tttttttatt gccgtttatt
      241 cggtaagctt ttctttctct cataatattt ggaggtgaat gaccatagca aaggatatga
      301 tggttaacga cggcattcgt gcacgagagt tacgattgat cggttcagat ggtgagcaat
      361 taggagttaa gacaaaagca gaagcattga atattgcaga acaagcaaac ttggatcttg
      421 tgttagttgc ccctggtgcg aaaccaccag ttgcgcgaat catggactac ggtaaatacc
      481 gtttcgaaca acaaaagaaa gaccgcgaag cgcgtaaaaa acaaaaagtg atcaatgtaa
      541 aagaagttcg cttaagtcct acgatcgact tgaatgactt caatacaaaa cttcgtaatg
      601 cacgtaagtt cttggaaaag ggcgataaag tgaaagcttc tatccgtttc aaaggccgtg
      661 ccattaccca taaagaaatt ggtcaaaaag tcttgaatcg cttagctgaa gaaactgcgg
      721 atattgcaac agtggaacaa aaagcgaaaa tggacggacg cagcatgttc ttgacgctgg
      781 caccgaaaaa cgacagtaag taatttgaat gactaactgg ctgttggaca gccgatagtc
      841 ggataacgaa agattttgag gaggaaatat agtcatgcca aaacaaaaaa cacaccgcgg
      901 atcagcaaaa cgtttcaaac gtactggtaa aggcggattg aaacgcttcc gcgcgtttac
      961 aagtcaccgt ttccacggca aaacaaaaaa acaacgccgt caattgcgta aagcaagcat
     1021 ggtttctagt ggcgacttca aacgtattcg ccaacaacta gcaaaaatga aataagaagt
     1081 acaaataaca gaatctgaag atttattttt attaggagga attatacatg gcacgtgtta
     1141 aaggtggaac agtaactcgt aaacgtcgta aaagagtgct aaaattagca aaaggttact
     1201 acggttcaaa acacacttta tttaaaacag caaaagaaca agtaatgaat tcatacaact
     1261 acgcatatcg cgatcgtcgt caaaagaaac gcgacttccg taaattgtgg attgctcgta
     1321 tcaacgcagc agctcgtatg aatggcttga gctactcaaa attaatgcac ggtttgaaag
     1381 ttgctgaaat cgacatcaac cgtaaaatgt tagctgactt ggctgttaac gatgcagcag
     1441 catttactgc attggctgac caagcaaaag aagctttggc taaataagct aaacaattat
     1501 aaagaggaaa gaagataacg aaaagttatg ttctttcctc tttttttatt tacaatcctc
     1561 catcaaatga aacaggacaa taacgtataa gtctaaaata acataattaa ggttttttaa
     1621 ttgaaaactg aacatttatg gtcatccttt aatgaaagcg ctaactacat aagttagaat
     1681 gagtttgact gatatattag tttgcttatc agaaaaacaa aatggacgga ggaataacat
     1741 gagtgatatt attattggta ttttgttagt tatctcattc tttttcatgg tctggtactg
     1801 tgtaaaaggc tacaacttga tggtcggctt ttgtcatcat ggctactgta tggatgggat
     1861 tagcgctagt cggaaacacg ttttcaccaa actcggcgat ggaagggcaa ggagtaattg
     1921 atgtgttgac gcatatctat acgacggggc cagctgagta cgccaaatcg atcttggtaa
     1981 atgtcttctt tggtgccttt ttcgggcgtg ttctagtaga tagcggaatc gcagctaccc
     2041 tgattcgaaa ggtagttgaa cttggagggg acaagccaag aatcacgatg agcttactat
     2101 gtattgtaac cgctgttata ttcatgtcga tgacaggaat cggaccagtg atttctattg
     2161 cagttattgt gttgccgatc ttgatgtcat taggt
//
LOCUS       DAFEKH010000142         2155 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.152, whole genome shotgun sequence.
ACCESSION   DAFEKH010000142
VERSION     DAFEKH010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2155)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2155)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2155
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.152"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            181..483
                     /locus_tag="LP386_002949"
     CDS             181..483
                     /locus_tag="LP386_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920113.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(999..1072)
                     /locus_tag="LP386_002950"
     tRNA            complement(999..1072)
                     /locus_tag="LP386_002950"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1036..1038),aa:Ile,seq:cat)
     gene            complement(1627..1941)
                     /locus_tag="LP386_002951"
     CDS             complement(1627..1941)
                     /locus_tag="LP386_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920114.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT          794 a          325 c          333 g          703 t
ORIGIN      
        1 ttttataagg gtttgagcat tttttatttt cgcagatttt cgttaaatga atgaaaatgg
       61 cattcaaaat agcattcaaa aagaacactt tttaatatat atgttccatc catattatca
      121 atgatattcc tactttacaa aaagaacatt agttcgtata ctctttttga ggtgaacatt
      181 atgttgatgg aaggaaaaac acaattatgg tttaaatttg atccttcgaa tagatttgtc
      241 aaagattttt ataaggtgtg ggattcagaa gttttctttt tagcaatcga agatagctta
      301 ttaatcaatc tctattactc taataagaac tactttaaaa ttccggcaac aaaaaccaga
      361 atgaagaaag atgtgtattt tttgtttgat atcgtgactg atgtgccaga cgcacggagc
      421 gatcatcggc gttatgacta tttgaagtat actttcgttg atccagaaag gtataaagat
      481 taaagtaggc tacctaaaaa aggtagcccg gaacggattt tatcaccata cttataaaag
      541 ggatattttt taagttagta ttaagattgt gtaatatgat gatatctata ttttatagta
      601 tcagtgctat aaaatcaaaa ataagtcact aattaactac cactccaatt ataagtcttt
      661 ttcccattat tttttacagt tatatggtat gctttttaat ggcttcaaat ataaaagagt
      721 ttaaagcgta acacacttat ggggaagtgg tttttgggga acgctttaaa ctcttcttta
      781 ttattatctc acaatataac ccaaatgtct ttccatttaa aaatcaaagt aaaacttttc
      841 aaatatacag aagtataact atgtgaaaca tcctttcatt aatccataaa aggatacata
      901 aaaaagccac tcatttgagt ggcaatgaag aaaagcttta gcttgtataa tactcttcaa
      961 aaaattctaa cacagaacga ttcaattggc tacattaatg taccctgtag gactcgaacc
     1021 tacgaccgga cggttatgag ccgtctgctc tgaccaactg agctaagggt agtggttgtt
     1081 gccacataaa gccataaaca atcaaccagt agaatgcgtg gcaacaaacc tgttatcgca
     1141 tatcttggag tgtgactatt tatgagtgat agtgaagata tgcgtctcca tatatgtatg
     1201 gttgagacag ataaacatgt atgaaaaacg ttgttaaatc aacgtttttt tattttggtc
     1261 aaggagagaa aagtagagaa atacaaaatt ttttgcattg attttgcatt caaaaaaaca
     1321 ttcaaacatt tagaaatccc caatacgtat tcaggaaaat ctattttaag gtttacaaaa
     1381 agaacttttg ttcgtacact ctttttgagg tgaactttta tgctgatgga aggaaaaaca
     1441 caattatggt ttaagcatgt tccttcaaat aagtttttta attataaact ctagagaaat
     1501 taattcatcc taacataaaa taattgttca ctcaaaagtt tttctagaac aattaaaaca
     1561 gcaggcttca cattcgctat acatttgtaa gaagtaataa ttcctgtact aaaaggcata
     1621 attgctttaa ttattttttg acttctcttc aaacacaaga agtagttgtg taataattgc
     1681 agaaataagg attccaataa tagatataaa atttgacatg gaaacgtcta taacattaaa
     1741 agaataaagt gttgaagaaa gtaaactgat tgaaataacc cctccgtaaa aaatagtctg
     1801 tgaatatacc cacttttttt cagaagacgt acttcgtttg gttctaaaac ctatccctgc
     1861 atttctactc ttatcaaaaa accaaatatt tagaagtaat aatattgcta ttattaagat
     1921 aaaattactg taaaaatcca aaagctatcc gagagtataa aatattttgt gtaaatgaaa
     1981 aaatccatac aaaaaaggaa gtcccttctg tagaataaag ttaacgacaa ccaattcaca
     2041 gaaaagagga cttccctatg aatgatttta ctacagaaat tgtgcaaact ctagtcacta
     2101 aaggcgattt aaatgaatta ttccgttcgc acttagaaaa agcgataaac acact
//
LOCUS       DAFEKH010000143         2100 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.153, whole genome shotgun sequence.
ACCESSION   DAFEKH010000143
VERSION     DAFEKH010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2100
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.153"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            92..1318
                     /gene="istA"
                     /locus_tag="LP386_002952"
     CDS             92..1318
                     /gene="istA"
                     /locus_tag="LP386_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001215400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HBL1920115.1"
                     /translation="MRKDVYEGVRFFMINDIKPNFNELGRQYNCDPRTVKKYYLEGSE
                     NSVKKDKDKPKRPSKLDPFKEIIDQKLELNCSAMAIFKFLKKIGYQGGYTIVKDYCRN
                     KKHTEIKKATLRVETVPGTAAQVDWKEDMTLHDKFGKSYTFNLFLYVLHFSKLKFITL
                     TWDRKQDTLFSCLYEAFNHTGGVPKEIWFDNMKTVVDRARTQYRKVVFNTRFYEFSKD
                     AGFEAIACRSYRPQTKGSVESLAKLVERLKPYDYEFYDAVDLISLVNTLCYDLNYEEI
                     SQSTYQRPVDLWEREEKGKLHPVNEALLTPYFEDNIVRIVTNESMVNFRKSKYSVPTK
                     YIGCEVEIEIDPTEKFIEIFYQGEVVQSHELTGKRLNYKETDMFEILKSDVMKHKDDE
                     EIYEYIQRTLTQYDEL"
     gene            1334..2092
                     /gene="istB"
                     /locus_tag="LP386_002953"
     CDS             1334..2092
                     /gene="istB"
                     /locus_tag="LP386_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HBL1920116.1"
                     /translation="MTTNHQKVLTNLDELGLLKMKEYYPHYLDSVRNQTISLTDALYN
                     LTQKQLDYQKEMIDKRAIKLARFPTIKSLEEFDFEFQPSINKHDILQLKSFHFLESST
                     NICFLGNSGVGKTHLATAIGIEACIQGVKTRFILFNDLIEKLTRASQRGTLVRTLKIF
                     TNVPLLIIDEIGYTPISKTQADWFYQLMARRYERASTIITTNIPFSMWAKNFDNTTAS
                     AAILDRLIHHSKVFKITGNSYRLKNYHLDKETIG"
BASE COUNT          738 a          339 c          380 g          643 t
ORIGIN      
        1 aatgtaggaa aacggcggaa taaaaatgtc gtttttccta catttttttc tatacacttt
       61 tcttaactca atctgaatgg aggttaattg attgagaaaa gatgtatacg aaggagttcg
      121 attttttatg attaacgata ttaaacctaa tttcaatgaa ttgggacgcc agtataattg
      181 cgacccacgt actgtcaaaa agtattatct ggaaggctca gaaaactctg taaagaaaga
      241 caaagataag cccaagcgtc cctccaagtt agatcctttc aaggaaataa ttgatcagaa
      301 attagaatta aattgttccg ctatggctat tttcaagttt ttgaaaaaaa ttggttatca
      361 gggtggctat actattgtta aggattattg tcgcaataaa aaacacacag aaattaaaaa
      421 ggcgacactt cgtgttgaaa cagttcctgg aacagctgct caagtcgatt ggaaagaaga
      481 tatgacctta cacgataaat ttggtaaatc ttacacgttc aatctctttc tgtacgttct
      541 acatttttct aaattgaaat tcattacatt aacttgggat cgaaagcagg acaccttatt
      601 ttcatgcttg tatgaagcat ttaatcacac cggaggtgtc ccaaaagaaa tatggttcga
      661 caatatgaaa actgtggttg atcgggcacg tacacaatat cgtaaagtgg tttttaacac
      721 tcgtttctat gagttcagta aagatgctgg ttttgaagct attgcgtgcc ggagttatcg
      781 acctcaaact aaaggctccg tagaatcttt agctaagcta gttgagagac tgaagcctta
      841 tgattatgaa ttctatgatg ccgttgactt aattagttta gtgaatacgc tctgttacga
      901 tttgaattat gaagaaattt ctcaatccac ttatcagcgc cctgttgatc tatgggaacg
      961 tgaagaaaaa ggaaaactac atccagttaa tgaagcgttg ttaactccct attttgaaga
     1021 caatattgtt cgtattgtca ccaacgaatc aatggtcaat tttagaaaat caaaatattc
     1081 tgtccctaca aaatatattg gttgtgaagt tgaaatagaa attgatccaa ccgaaaaatt
     1141 tatcgaaata ttctaccaag gagaggttgt acaatctcac gaattaactg gtaagcgcct
     1201 gaactataaa gaaactgata tgtttgaaat attaaaatca gacgtgatga aacacaaaga
     1261 tgatgaagaa atttatgagt atatacaacg aacattgact caatatgatg aactttaagg
     1321 agctgaaata ataatgacaa caaatcacca aaaagtgtta accaatttag atgagctagg
     1381 cttattaaaa atgaaagagt attatcctca ttaccttgat tccgtgagga atcagacaat
     1441 ttctttgaca gatgcattgt ataatcttac gcaaaagcaa ctggattatc aaaaagaaat
     1501 gatagataag cgtgcaatta aacttgcgcg cttcccaact attaaatcat tggaagaatt
     1561 tgattttgaa tttcagccta gcattaataa gcatgacatt ctgcaactca aaagttttca
     1621 cttcctagaa agtagtacga atatttgttt tcttggcaat agtggggttg gaaaaactca
     1681 cttggctaca gctataggga ttgaagcatg cattcaagga gtcaaaacaa ggtttattct
     1741 ttttaacgat cttatagaaa aattgactcg tgcgagtcag aggggaacat tagttagaac
     1801 actaaaaata tttaccaatg ttcctttact gatcatagat gaaattggtt atacgccgat
     1861 tagtaagaca caagctgatt ggttttatca actgatggca cgtcgatatg aacgcgcttc
     1921 tacaattatt acaacaaaca ttccattttc tatgtgggcg aaaaattttg ataatactac
     1981 agcttcagca gcaattttag atcgattaat ccatcactct aaagttttta aaattactgg
     2041 taattcttat cgattgaaaa attaccactt agataaagaa acgatcggct aataacaggc
//
LOCUS       DAFEKH010000144         2099 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.154, whole genome shotgun sequence.
ACCESSION   DAFEKH010000144
VERSION     DAFEKH010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2099
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.154"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            169..1539
                     /locus_tag="LP386_002954"
     CDS             169..1539
                     /locus_tag="LP386_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4357 domain-containing protein"
                     /protein_id="HBL1920117.1"
                     /translation="MMDKSNEEQTTLYTKYWRRLEEVFDNSKGMEDFFRYYLAAITGE
                     YSAKHILYQAFKDYWHKERDVSSDAELLQKLVRYAGYFARLYYNKPEGKYSEVLSDFQ
                     SMESMMPAPFVLGLSEWYYHDQFITEDQYIDAIKVVNDYQLRRYFNGDDTSRVSKAFP
                     SYLKSVRKYAKANGYENIVDIVIYVLVTRNQSNNMALPSDKALKSNLLNANAYAMRLA
                     RWLLEKIENRENSATLDMSNLSIEHIMPQTSTSYWEEKAGTSGEEYTGLVNTIGNLTL
                     VTNPDNSAAGNKDFETKKKIFEDTLHIRMNKDLYELTEWTSSDISARSEALINELITM
                     YPYLRSSGDYEHDGNREIFLEAQGIKATGYLNEDETVIIHSGSEIYSKIKDIASDSLD
                     ETRQELLDNGIIEETIGGLQFVQDYTASSVSNAAALLLGGSRNGWDYWKYDNGISIND
                     SLRNKK"
     gene            1560..1844
                     /locus_tag="LP386_002955"
     CDS             1560..1844
                     /locus_tag="LP386_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920118.1"
                     /translation="MDKNKLRYAILKLRDEKKNPFIELKGQVPEEDILEQTKFLSRNG
                     LLESMVWADNTVHIWGSVSLEGEKYLVENSGLAKAYALAKEVKNWIPFWG"
BASE COUNT          728 a          307 c          444 g          620 t
ORIGIN      
        1 ttgatttacc aacatgttta gacattttcc tctaggaaaa aattaactag caccacgcgt
       61 attgtttata ttaaattaga tgaccgtgat aatgcacagc aaatttttga aagtatcaat
      121 tctaccggtg aaagattgac tgcctcggat ttgattcgaa acttcatcat gatggataaa
      181 tctaatgaag agcagactac gctttatact aaatattggc gtaggttgga agaagtcttt
      241 gataattcta aaggaatgga agactttttc agatactacc ttgctgcaat aactggggag
      301 tattcagcaa agcatattct ttatcaagca ttcaaagact attggcataa agagcgcgat
      361 gtatcaagtg atgccgaatt gctccaaaaa ttagtgcgat atgctggtta ttttgcgaga
      421 ctttactata acaaacctga aggaaaatac tcagaagtat tgagcgattt ccaaagtatg
      481 gaaagtatga tgcctgcacc ttttgttttg ggattatctg aatggtacta tcatgaccaa
      541 tttatcactg aagaccaata tattgatgcg attaaggtag tgaatgatta tcagcttagg
      601 agatatttta atggggatga tacaagcaga gtgtcaaaag catttccttc atatttgaaa
      661 agtgttagga agtacgctaa agctaatgga tatgaaaata tcgttgatat tgtaatttat
      721 gttcttgtta ctagaaatca atcaaataat atggcacttc catctgacaa ggcattgaaa
      781 tctaatctat tgaatgccaa tgcttatgcg atgagattgg cccgttggtt acttgaaaaa
      841 atagagaatc gagaaaattc agcaacactt gatatgagta acttgtccat tgaacacatc
      901 atgccacaga ctagtacttc atattgggaa gagaaggctg gtacatcggg ggaagaatac
      961 acaggattag taaataccat tggtaattta acactcgtta caaatcctga taattcggcc
     1021 gcgggaaata aagactttga gaccaaaaag aaaatctttg aagataccct tcatattcgt
     1081 atgaataaag atttgtacga attgactgag tggacatcat cggatatttc tgccagaagt
     1141 gaagctctaa tcaatgaact gattactatg tatccctatt tgagatcgtc gggcgactat
     1201 gaacacgatg ggaataggga aattttctta gaggcgcaag gaataaaagc aactgggtat
     1261 ttgaacgaag acgagaccgt gattatacat tcaggttcag aaatttattc taagattaaa
     1321 gatattgcat ctgattcgct agatgaaact cgccaagagc tgttggataa tggaatcatt
     1381 gaagaaacaa ttgggggact acaatttgtt caagattaca ctgcctcatc tgtttcgaat
     1441 gcagcagctc tgctattagg gggtagccgg aatggttggg actactggaa atatgataac
     1501 ggaataagta ttaatgattc gctaagaaat aagaaataga gcatagaggt ggtgttaggt
     1561 tggataagaa caaactaaga tatgcaattc ttaaattgcg tgatgaaaaa aagaatcctt
     1621 ttattgagct taaagggcaa gttccagaag aagatatttt agaacaaact aaatttcttt
     1681 cgcgcaatgg cttactagaa tccatggttt gggcggataa cactgttcat atctggggga
     1741 gtgtttctct ggaaggggaa aaatatttag ttgaaaactc aggtcttgct aaggcgtatg
     1801 cattggcaaa agaagttaaa aattggattc cattttgggg ctaagataag tttttaaacg
     1861 gagaaggtag caaatcataa ttggtttgtt gccttttttg attgcccaaa aagaaaaatg
     1921 acaaagtata gagataaatg acatagtaca cgggaaaaat gacattgtat caccgacaac
     1981 gtctaaatag atgttgatat atatacgttc cgtacaaata attataaaaa tttaaatgat
     2041 ttgagtagaa gtatcagtga atatctcaag gggaatagct atctcaagat tcgattttc
//
LOCUS       DAFEKH010000145         2021 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.155, whole genome shotgun sequence.
ACCESSION   DAFEKH010000145
VERSION     DAFEKH010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2021
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.155"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..449)
                     /locus_tag="LP386_002956"
     CDS             complement(<1..449)
                     /locus_tag="LP386_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1920119.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYLK"
     gene            793..1200
                     /locus_tag="LP386_002957"
     CDS             793..1200
                     /locus_tag="LP386_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920120.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            1214..1615
                     /locus_tag="LP386_002958"
     CDS             1214..1615
                     /locus_tag="LP386_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920121.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1617..1988
                     /locus_tag="LP386_002959"
     CDS             1617..1988
                     /locus_tag="LP386_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920122.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
BASE COUNT          716 a          283 c          330 g          692 t
ORIGIN      
        1 ttttttaaat atgcgttctc tgctcttaaa cgaataactt cttcttcaag agactcatct
       61 ttaagttttt taggaatgtt tagcttggaa ttcatactaa tttttctgcc ccttttttgg
      121 ctctcaagtg aagaagcacc gccttcttca tattgctcta tccatttact tagagttcta
      181 tttgaaccga tattaaattt tttagcagtt tcttggatag aaagaccatt tgtttccata
      241 tattctataa catcaagttt aaattttgta gtgtagcttt tgccacctcc aaccaagcct
      301 tcccaaccat gatagttata aatccttacc caatgtctaa ccagtgtacg atttatttga
      361 tatttatgtg caagatattt gtagccgcct tcgttattta aatagtctga aactactttt
      421 ttcttaaaaa caaatgtata tttccgcaaa aaaagcaccc cttttaatta gatttctagt
      481 ctaacttttg gggtgcacat catttttgag gggaagtaca tatagttgtt gatatagttg
      541 ctaatattgt tagctaattt gttagtaaaa ctgtatacga atttagatag taaaaaaaca
      601 gtttgttcct tatatagagg cacttttact actgattaaa tgtcagatat gcttacaaat
      661 atacttataa atatgcttac aaaattagct aatatttccg ttgacaaagc tttgttacta
      721 ttgttaaact aaattgacta gcaaaagtga aacataaatt tattaaataa atgtaaaaat
      781 taggagaaat caatgtctta tagagtacaa ttaataattt cagaagatgt agaaagtcag
      841 caatttggca ctaatgttat taataaagta attaatccag ctctttctat taatgcgcct
      901 ttaattccta ctgctttatc attttctgta acagctgtgg tgtctgagat agaggataca
      961 gaaaagataa aaatagtaga aattgaagtt ttaaacaaga atgaaaaaca aattttttct
     1021 acgggtgaag tatcggtaag cttgcctcct caagttaacg atataaactt taatataaac
     1081 gccagaaatg tcttggttga agaagcagga gagcattatg ctgttgttaa atttaatgga
     1141 actgagattg gaaggcaaat ctttgatatc aaggtcaaca aaccagtgga aaaaaattaa
     1201 ggagacgata cggatgcttg atatagtacc atcaaataca catcggagtg gtagcttaat
     1261 aaattttgct gcgatttttg cttgcgcatc ggtaattcta gcatctccag ttgttgtgga
     1321 tgcaagttct actccgaaaa ctaaaaatga taatcaactt gtaattacta caaaaaatga
     1381 gattaacaca atttcaagta atgatggcaa aatttttgat gtgataaata cggttttaaa
     1441 aagaaaagct gaaatcaata taaaatatga tgaagattta aacttgtatt tctttgttat
     1501 caaaacaaca tctgaattgt tttcctcaga ttacgatgtt ttggatactc tcgataatgt
     1561 attatctgac tataaatata tggggaaatc tgtagtagca actttggggg aataaaatgt
     1621 ttgactttaa tgaatattta tctatttcca aacaaattga atcagatgat aaatataatt
     1681 ctaaagaatc ttatagaaga actgctgttt caagagcata ctacagtgct tttaaaaaat
     1741 ctgatgagta tttgaaagaa aattatgata ttatttataa tggaagtagc ggaaaaggaa
     1801 gccaccaaac cgtttggaat ttgttttcaa cagttaagga attgaatacc ttaggaatac
     1861 ataatagtgg gtatagaatg ttagagaaaa gaaaatgtgc tgactatatt cctaatgaaa
     1921 ccattacgaa aacagatatg gcgctgatga atcgagaagc agaaaaaata ataaacaaac
     1981 tcacctaatg aatttcaagc gagtttgttt gttatttttt t
//
LOCUS       DAFEKH010000146         1966 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.156, whole genome shotgun sequence.
ACCESSION   DAFEKH010000146
VERSION     DAFEKH010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1966)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1966)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1966
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.156"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..530
                     /locus_tag="LP386_002960"
     CDS             <1..530
                     /locus_tag="LP386_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HBL1920123.1"
                     /translation="FEYLKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFL
                     RNIFTTIPKKNSKSFREAVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDG
                     FEDAFQYTVQGNSHNRLKSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLH
                     DEWIYSSRKYINFDK"
     gene            complement(660..>1966)
                     /locus_tag="LP386_002961"
                     /note="aph(2'')-Ia"
     CDS             complement(660..>1966)
                     /locus_tag="LP386_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HBL1920124.1"
                     /translation="LKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYP
                     KTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRA
                     YQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSI
                     EIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYS
                     YISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECT
                     IDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNH
                     LLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKA
                     KEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT          663 a          344 c          201 g          758 t
ORIGIN      
        1 tttttgaata cctaaaagaa cgcggtttac aaggtacgga actcgttatt tctgatgcgc
       61 acaaaggatt agtctctgcc attagaaaat ccttcaccaa cgtaagttgg caaagatgcc
      121 aagttcactt cctaagaaat atctttacca ccattcctaa aaaaaattca aaatctttca
      181 gagaagctgt taaaggaatt tttaagttca cagatattaa cttagcgcgt gaggctaaaa
      241 atcgattgat tcatgattat atcgatcaac caaaatattc aaaagcttgc gcatcattgg
      301 atgatggatt cgaagacgcc tttcaatata ccgtacaagg aaattcccac aatcgactaa
      361 agagtaccaa tctaattgaa cgactgaatc aagaagtacg cagaagagaa aagattattc
      421 gcatcttccc caatcaaaca tcagccaatc gcttaattgg agccgttctt atggacctac
      481 atgatgaatg gatttattct tcaagaaaat acatcaattt tgataagtag aaatggtaaa
      541 aacattgtat agcattttac acaggagtct ggacttgact cacttccttt attatttttc
      601 atttttttaa actatttaat actaatgtct tttataatag cttttcatat attatataat
      661 caatctttat aagtcctttt ataaatttct tttctaccat tttcgataaa ttcctgttta
      721 atatttttaa ttccataaac aatagtttca ataggataat attcttcaac tatatcttga
      781 tattcttttg ctttctcaat atctatattt ccatacattc ttaatatatc ttctccaaaa
      841 tttgttccta tttcttcttc actatcttca agtaagtata taaaatcaca atattcatct
      901 ataattccag aatctccaaa atcaattatt ccagttaatc tattattgcc atctaacaat
      961 agatgattac aactaaaatc attatggcat aaacactttt taccctcaaa aactgttgtt
     1021 gcatttagtc tttccataaa actttctata taatcttttt ctatatcagt taaatcatta
     1081 taaatagttt cacgcaacaa tatatactct tctaatacat tttgtttatt atcaatagta
     1141 cattcactaa tatctgtata atctaaaccg tgcatttgtc ttaaaaaact ggcaatatct
     1201 cgttttaaca aattttgttc ttcttctgac atagtagaat aaatttctgg tgttaaaaaa
     1261 gttcctttaa tttctttata acctagtata gataattcat cactaatata cgaatattca
     1321 atattaggaa tttttacatt agtttctaaa tttgtattta aaaaattata tattgctttt
     1381 tcttttgcat aacctttttt cttattagta ctaaattttg ttttaaaaat gtattcatta
     1441 ttaactaaat atgccacact atcataacca ctaccgatta tttcaatact atctactttg
     1501 aaattatcaa agtaatgctc aattaaatat ttcattgcct taacatttgt ggcattatca
     1561 tcatatctat attccattaa ataacaatct tcttttttgc cctcgtgtaa ttcatgttct
     1621 ggcaaatctt caataattct aaaaccagat ttttggtatg cccttattgc tcttggatta
     1681 tttttatgag ggtctaaaat aactgcatta gcatttcttt cttttttcaa aaattcaaaa
     1741 atcaatttaa tatatcttgt accaattcct ttactccaat aatttggctc tcctataaat
     1801 tgatccatac catagactat ctcatcagtt tttggataat gataatcagt atataactca
     1861 tcatacattt tatatatttg tccatatcca ataggaacat tgttatattc aataattact
     1921 ctaaaaactt catcttccca aggctctgta taatgttttt ttaatg
//
LOCUS       DAFEKH010000147         1924 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.157, whole genome shotgun sequence.
ACCESSION   DAFEKH010000147
VERSION     DAFEKH010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1924
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.157"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..316
                     /locus_tag="LP386_002962"
     CDS             <1..316
                     /locus_tag="LP386_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920125.1"
                     /translation="KEAAWRKLMLLIQDENWQEDEAVVAEVQRLGKIANGRIRKKPDK
                     RKQRKGKIVVVLHEGKILMQGTASELSAETGYTRGTIRTYAWRNHTDRKGHEYKYLEE
                     EK"
     gene            313..1128
                     /locus_tag="LP386_002963"
     CDS             313..1128
                     /locus_tag="LP386_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prohibitin family protein"
                     /protein_id="HBL1920126.1"
                     /translation="MNENKLIKLGVAGAVIVGIGVIGGFKFFEKIDNGYVGVRYSMNG
                     GIKDEALTQGVKFVGIDKVIQYPIRLQTIQSKNISVSTSDGKKTTIDIKYDYKVDSTK
                     AAKMYKEFGNITSEDIESGWLKSKLQKVAREVYAKYSLLDVLSGDSSKVEAEVLTNFA
                     KSVESKGFEVEDVTLGVPDVDKETQKSIDAIIRAGQENEKAKLDAETAKTQADSEAYK
                     KTKAAEAEAESNRKVAESVTDNLIRYEEAQARKKHGWVTVNGADTVVTDEAGK"
     gene            1267..1578
                     /locus_tag="LP386_002964"
     CDS             1267..1578
                     /locus_tag="LP386_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBL1920127.1"
                     /translation="MDELITKVEQWAKDKGLDQADPKAQFLKVAEEFGEIASAMARSN
                     DELFKDSVGDVIVTLIILSMQKGTNVQECLEMAYNEIKGRTGKMVDGVFVKSSDLEDV
                     K"
     gene            1575..1805
                     /locus_tag="LP386_002965"
     CDS             1575..1805
                     /locus_tag="LP386_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920128.1"
                     /translation="MKYEIPLSEAGIQAIINGREVNIELPDGTELVIRQSYLKDMAAP
                     VLIDRFNVTDSVVENHLKEFRSSIDNTFRLGS"
     gene            1812..>1924
                     /locus_tag="LP386_002966"
     CDS             1812..>1924
                     /locus_tag="LP386_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HBL1920129.1"
                     /translation="MNTRHRRVAKLRKQELNVLKTKFEKEYGISAEETYKVA"
BASE COUNT          719 a          294 c          462 g          449 t
ORIGIN      
        1 taaggaagcg gcttggcgaa aattaatgtt gctgattcaa gatgagaact ggcaagaaga
       61 tgaagcagtg gttgctgaag ttcagcgtct aggaaagatt gctaacggac gtatacgaaa
      121 aaagccagac aaaagaaaac agcgcaaagg gaaaatcgtc gttgttttac acgaaggcaa
      181 aattttgatg caaggaacag ctagtgagct gtctgcagaa actggatata cgcgtgggac
      241 tattcgaacg tacgcttggc gaaatcacac cgatcgaaaa gggcacgaat ataagtattt
      301 ggaggaagaa aaatgaacga aaacaaatta atcaaattgg gtgtagcagg agcagtaatc
      361 gtaggtattg gagttatcgg aggatttaag ttcttcgaaa aaatcgataa tggatatgtg
      421 ggtgtgcgct attcaatgaa cggcggtatc aaagatgaag cactgacgca aggtgtgaaa
      481 tttgtaggga ttgacaaagt gatccaatat ccaattcgct tgcaaactat ccaatcaaaa
      541 aatatttcag tatctacaag cgacggcaaa aagacaacga ttgatatcaa atatgactac
      601 aaagttgatt caactaaagc agcaaaaatg tacaaggaat ttgggaatat cacttcggaa
      661 gatatcgaaa gtggatggtt aaaatctaag cttcaaaagg tcgctcgtga agtttatgcg
      721 aaatatagtc tgcttgatgt cctttcagga gattcctcta aagttgaagc tgaggtatta
      781 acgaactttg ctaaatcagt tgaatctaaa gggtttgaag tcgaagacgt aacacttggt
      841 gttccagatg tcgataaaga aacacaaaaa tcaatcgatg cgatcattcg agctggtcaa
      901 gaaaatgaaa aagcgaagct agacgcagaa actgcaaaaa ctcaagctga tagtgaagct
      961 tacaagaaaa caaaagctgc agaagcagag gcagaatcta atcgcaaagt cgccgaatca
     1021 gtaacagaca atttgattcg ttatgaagaa gctcaagctc gcaaaaagca tggatgggta
     1081 acagtaaatg gagcagatac tgtagttacg gatgaagcag gcaaataata tgggattctt
     1141 tatggctaaa attctcttgt tcttaggttt agtaggagca gcatatctcg tgtatgcgct
     1201 cctttcccaa actgatgaca aagaagatga caacaacgat gaaatgaaat tttaggagga
     1261 gaaataatgg acgaactaat cacaaaagta gagcagtggg ctaaagacaa gggactggat
     1321 caagcagatc caaaagcaca gtttttgaaa gtagctgagg aattcgggga aatagcttcg
     1381 gcgatggcaa gaagtaatga tgaactattt aaagatagcg taggagacgt tatcgtcacg
     1441 ctgattatcc tttccatgca aaaagggaca aacgtacaag agtgtttaga aatggcatac
     1501 aacgaaatca aaggacgcac agggaaaatg gtagatggtg tattcgtgaa gtcgagtgat
     1561 ttggaggatg tgaaatgaaa tacgaaatac cactaagtga agcgggcatt caagcaatta
     1621 tcaatggtcg ggaggttaac atagaacttc ctgatggtac tgaattagtc atcagacaaa
     1681 gttatttgaa agatatggca gctccagtat taattgatcg ttttaacgtg actgattctg
     1741 tggtagagaa ccacttaaaa gaatttcgat caagtataga caacactttc agattaggga
     1801 gttgattgac aatgaacacc agacaccgca gagtagcaaa actaagaaaa caggaactaa
     1861 atgtactaaa gacaaagttt gaaaaagaat atggaatttc agcagaagaa acatataaag
     1921 tggc
//
LOCUS       DAFEKH010000148         1744 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.158, whole genome shotgun sequence.
ACCESSION   DAFEKH010000148
VERSION     DAFEKH010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1744
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.158"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            131..505
                     /locus_tag="LP386_002967"
     CDS             131..505
                     /locus_tag="LP386_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBL1920130.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="LP386_002968"
     CDS             complement(619..1248)
                     /locus_tag="LP386_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBL1920131.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="LP386_002969"
     tRNA            complement(1382..1454)
                     /locus_tag="LP386_002969"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
     gene            1668..1741
                     /locus_tag="LP386_002970"
     tRNA            1668..1741
                     /locus_tag="LP386_002970"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1702..1704,aa:Asn,seq:gtt)
BASE COUNT          602 a          256 c          306 g          580 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt acttgattcc ggcatagctc
     1681 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactgccgga
     1741 gtaa
//
LOCUS       DAFEKH010000149         1679 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.159, whole genome shotgun sequence.
ACCESSION   DAFEKH010000149
VERSION     DAFEKH010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1679
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.159"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(365..1657)
                     /locus_tag="LP386_002971"
     CDS             complement(365..1657)
                     /locus_tag="LP386_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBL1920132.1"
                     /translation="MARKKRNPDAEKLAESILNAYQPESVDDMQDALKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKEHDNRRNGYGTKTLKTSFGEVAIDVPRDREASFEPELIP
                     KRKRDVSDIEGKVLSMYARGMSQRDIAATVEAIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKARGVEDVFFISMDGVSGLEEGAKAIFPSVIVQRCIVHLVRNALRYIPSK
                     DYKEVCRDMKKFYGASSLNAAHAAFDSFQNRWSHYSGAVDVWKRNFAHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENALLKLLYLRTKELHAKWSGGRIQNWAM
                     VLNQLMINETFSSRMKSMRFTFRNNGRFIQLCVRSKFI"
BASE COUNT          516 a          343 c          284 g          536 t
ORIGIN      
        1 tatgggctac tctgtgatac ttattagcca ttaaactatt ttacccacat agcatatatt
       61 ttgaaatcgt tcattccgta aattcaacta aatatgccta aaaaaataaa aaatctaaga
      121 tagaataaga tttattcagt cttagatgga tttatagcaa ctttttcgta acaactttaa
      181 aaaatacgaa aagaaagagc tgttttactc tgactacgtt gctaaattgt cgtttaatca
      241 ttcatttaaa ccaaatcttt ttttatagaa ttcgttttaa tcctcctgaa tccaaaaact
      301 atgaaaaccg taattaaata gttaagagtt tttaaccacc ataattctct cggctatttt
      361 gaaatcagat aaattttgat cggacacata gttgaataaa cctaccgttg ttacggaagg
      421 taaatcgcat acttttcatt ctagaggaga aggtctcgtt gatcattaac tgattaagca
      481 ccatagccca gttttgaatt cgaccacctg accacttcgc gtgtaattct ttcgtgcgta
      541 aataaagtag ttttaggagt gcattctcat tagagaacgc tccttttttt gtgacttttc
      601 tgaagctgga gtggacactt tcaaccgcat tggtagtgta cataattttt cgaatggcac
      661 taccataatc aaatagttgt tcaacatgtg caaagttccg tttccagaca tctacagcac
      721 cagaataatg agaccaccga ttttgaaaac tgtcaaaagc agcatgtgca gcgtttagag
      781 aagaagcacc gtagaacttt ttcatatctc ggcagacttc cttatagtcc ttacttggaa
      841 tatagcgcaa tgcatttcga acaagatgaa caatacagcg ctgaacaatt accgatggaa
      901 agatcgcttt tgcgccttct tcgaggccag aaacaccgtc catcgaaatg aaaaagacat
      961 cttcgacacc acgtgctttc agttcatcaa atacttgcat ccagcgattt ttagattctg
     1021 tttgatttaa ccataatcct aaaatctcct tatttccttt gagatcatag ccaagaatgg
     1081 tgtatacagc atattctttg gcttcataat tttctcgtaa agtaacatac atacaatcaa
     1141 cgaatagaaa ggcataacac tttgctaggg ggcgggcttg ccattcttcc aattcaggaa
     1201 ggacagcgtc agtgatatct gaaatcattt catgggaaat atcaaagcca taaatagctt
     1261 cgacggttgc ggcaatatct cgttgactca ttcctcgtgc atacatggaa agaaccttcc
     1321 cttcgatgtc ggagacatct cgttttctct taggaattaa ctctggttca aaggaagctt
     1381 cccggtctct aggaacatca atagctactt caccaaaact ggttttaagc gttttagttc
     1441 catagccatt tcgacggtta tcgtgttcct taggctcttt agaatgggca tcataaccta
     1501 aatgattatt caattctcct tgaagcattt tttcaaaaag gggcccaaac acatctttca
     1561 aagcatcttg catgtcatcg acagattcag gttgataggc attcagaatg gattcagcta
     1621 acttttcggc atcaggattt cttttctttc tagccatcgt gtaatcacct cttgatctt
//
LOCUS       DAFEKH010000150         1589 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.161, whole genome shotgun sequence.
ACCESSION   DAFEKH010000150
VERSION     DAFEKH010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1589
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.161"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            172..459
                     /locus_tag="LP386_002972"
                     /pseudo
     CDS             172..459
                     /locus_tag="LP386_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            473..904
                     /locus_tag="LP386_002973"
     CDS             473..904
                     /locus_tag="LP386_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920133.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
     gene            906..1043
                     /locus_tag="LP386_002974"
     CDS             906..1043
                     /locus_tag="LP386_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBL1920134.1"
                     /translation="MYSYEDIKLMYDWGCFTNEQVMVFVPLCITDEEADKIINKDKSA
                     S"
     gene            1080..1373
                     /locus_tag="LP386_002975"
     CDS             1080..1373
                     /locus_tag="LP386_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920135.1"
                     /translation="MINLGEWGMIAGSITAIVSLILLVIRPIAASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERRK"
     gene            1370..>1589
                     /locus_tag="LP386_002976"
     CDS             1370..>1589
                     /locus_tag="LP386_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBL1920136.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGN"
BASE COUNT          580 a          232 c          339 g          438 t
ORIGIN      
        1 gctaaatact taaaaacgca tgtagaagct attgatggta aagaagcatt ggtgcagaca
       61 gatggagacc aagccattgc aggacataag aatttttcag gttctgtaac aatcaataat
      121 aaacgtgttt tgacgactga tgataacaga tatgaagtgg taaatctggt tgtcactaac
      181 ggtaatacag ggacagcaaa gctttatcgt gaaggaaaaa cagtttctat atattttgtg
      241 gctttaaacg gaaaaagtag tggcgggaat gattcggtta ttttaactgt tccagaaggc
      301 tatcggacac caattagttt tgaacaactg gttgggtcaa tagaccgttc tactttgaac
      361 agtgctcaac tatctattgg cgcagacgga gccattaaat ggagaagaaa ttcaagttat
      421 ggatcagctt attcatttgt tatcacttat tcaatttaag ggaggaaatc taatgaaagt
      481 agtttacaaa tcaatcaagc cttacggatt cgagcaaatc attttgaaca atcaagaaaa
      541 tatccctgaa aactgtacag agattaaacc accagttcct aactggagac caagatttga
      601 ttttgataaa aaacagtggg ttgagttagc tactgaagaa gagaaaaaag ggaatgctgt
      661 tgatagcgta gatgaattgg ctaatattaa ggcattatac gaaacgctga aggcagaaaa
      721 tgatgaattg aaacagctaa attctaaagc aatgctaaac aatgtagcaa tcaagcaaga
      781 aaatgtctta ttgaaagaaa agtcagaaag tttagcgcag ttgaattcaa aaacgatgct
      841 tgcttctgta caaaatacca aggaaatcga agaaatcaaa aaacaattac aaggtgggaa
      901 gtaacatgta ttcatatgaa gatatcaaac taatgtatga ctggggctgt ttcactaacg
      961 aacaagtaat ggttttcgtt ccattatgca ttacagacga agaagcagat aaaatcatta
     1021 ataaagataa gagcgcatct taattgatgc gtttttattt aaggtaaagg agttgtcaca
     1081 tgattaattt aggggaatgg ggaatgatag caggatcaat aaccgctatc gtttctttga
     1141 ttttattagt aattagaccg attgctgcat ctttctcgaa aattactgag actctttcaa
     1201 aagtaagcca caatttagat ttgctgacta aagatttaga atcgagcaaa tcagatcgat
     1261 tgatgattca tgaagaacta aagaaacacg atgaaagatt agatacacat acagaaaaat
     1321 tggtggaaca cacgcaacaa atcaaaactt tgtttaggga gagaagaaaa tgaataataa
     1381 aacgttcgaa gtactaaaat ggttcgcact ggtaattatt cccgcactag ctactttcgt
     1441 ggggttagtt ggtaaagcgc tcaattggca gtacacagat atctgtgttg tcatcattac
     1501 tggttttggc gcgtttttag ggagtgtgtt gggtgtatca aatcgaacct acaaaatgtt
     1561 ctcggctgaa agcgaagaag gaggaaaca
//
LOCUS       DAFEKH010000151         1584 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.162, whole genome shotgun sequence.
ACCESSION   DAFEKH010000151
VERSION     DAFEKH010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1584
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.162"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            292..1479
                     /locus_tag="LP386_002977"
     CDS             292..1479
                     /locus_tag="LP386_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBL1920137.1"
                     /translation="MYFLGIDIGKRTHVASIMNEEGKVLLKGFSFPNTTEGAESLIER
                     MVDYSGAPSDFVIGMEATGHYWLSIFSYLHESDYLIHVVNPLQTDGWRKGTEIRKRKN
                     DIIDSVLIADLMRYGSFVETVLSDENVFSLKQLSRYRTYLVGTASDFKRKIIAVLDQV
                     FPEYATIFTKQGVFGKASKELLLAFSAPIDLENISSETLAQYLAELSRNRIKAEKADQ
                     LKQAASNSFGVKFAQEAFTFQLRSMIEQLKFIESQIKETEREIKHIMDTLNSVILTIP
                     GIGPINGATILGEIGDIQKFSNPKKLVAYAGIDASVTQSGQYEATHNVMSKRGSPYLR
                     KALFSAALVASQCDPVFSAFYQKKVSEGKHHLTALGAVSRKLCYVIHAILTKNEPYII
                     VSD"
BASE COUNT          468 a          295 c          314 g          507 t
ORIGIN      
        1 ttttaacctt ccggttttga ttggataacc ctatgaacca tcgttatttt aatttggtat
       61 taactcattt cttttgagat aatatattta ttggattgag aggctaagcc gttcccccct
      121 tgggtcattg aacccgcact cgagagactg gctcctctct ctgataagtg tattgcgtat
      181 gagttagatg ttgaaagtcc ttactttact ccgtatctcg tacaaggtag tgacgctttt
      241 cagttgagtg gatttcaatc caaaattctt tttttgaaag gtcagatata catgtacttt
      301 ttaggcattg atatcggtaa acgcactcac gttgcttcta tcatgaacga ggaaggaaag
      361 gtattactaa aaggtttttc atttcctaac accactgaag gagcagagtc attaattgag
      421 cgaatggtcg actattccgg agcacccagt gactttgtta tagggatgga agccacgggg
      481 cactattggc tgtccatctt ttcatacctt cacgaatcag attatttgat tcacgttgtg
      541 aatccccttc aaacagacgg atggcgtaaa ggtacagaaa tacggaaacg aaaaaacgat
      601 attattgatt ctgttttgat tgctgactta atgcgctatg gctcatttgt cgaaacggtc
      661 ttatccgatg aaaatgtttt ttctttgaaa caactttctc gttaccgaac ttatttagta
      721 ggtacagcga gcgacttcaa aagaaaaatt atagccgtat tggatcaagt ctttccagaa
      781 tacgcgacga tttttaccaa acagggcgtt ttcggaaaag cttctaaaga gttattgctg
      841 gcgtttagtg ccccgatcga cttagaaaac atttcctcag aaactttggc ccaatactta
      901 gctgagttaa gcaggaaccg aatcaaggca gaaaaagcgg accaattgaa gcaagcagct
      961 tctaactcct ttggagtaaa atttgctcaa gaagcgttca ccttccaact acgttcaatg
     1021 attgaacaat taaaattcat tgaaagccaa ataaaggaaa cggaaagaga aatcaagcac
     1081 ataatggaca ctttaaattc tgttattctc acaattcctg gaattggtcc tataaacggt
     1141 gcgactattc ttggtgagat cggagatatt caaaaatttt ctaacccgaa aaaactcgtt
     1201 gcttacgctg ggatagacgc ttccgtgaca caatcagggc aatatgaggc aacgcataat
     1261 gttatgagta aacgagggtc tccatatttg cgaaaagcct tgttttcggc ggctttagta
     1321 gcttctcaat gtgatcctgt ttttagtgcg ttttaccaga aaaaagtttc cgaaggaaaa
     1381 catcatctaa ctgccttagg tgcggtttct cgtaagcttt gttacgtgat tcatgctatt
     1441 ttgactaaaa acgagcctta tataattgtt tctgattagc tattgaacat tcaaaaaaac
     1501 taatggtaag aagcttattt gttgtaccct tttttcggaa ttatctgtta taaaatattt
     1561 tttgatttgg ctaattttta cttg
//
LOCUS       DAFEKH010000152         1519 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.163, whole genome shotgun sequence.
ACCESSION   DAFEKH010000152
VERSION     DAFEKH010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1519
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.163"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(329..628)
                     /locus_tag="LP386_002978"
     CDS             complement(329..628)
                     /locus_tag="LP386_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920138.1"
                     /translation="MLFNETQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKDVYFLFDIVTDVLDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(634..864)
                     /locus_tag="LP386_002979"
     CDS             complement(634..864)
                     /locus_tag="LP386_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920139.1"
                     /translation="MMEEFIRKNISDEYADFYEQSNEKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            complement(1114..1314)
                     /locus_tag="LP386_002980"
     CDS             complement(1114..1314)
                     /locus_tag="LP386_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL1920140.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
BASE COUNT          539 a          244 c          223 g          513 t
ORIGIN      
        1 aaagacattt gggttatatt gtgagataat aataaagaag agtttaaagc gttccccaaa
       61 aaccactgcc ccataagtgt gttacgcttt aaactctttt atatttgaag ccattaaaaa
      121 gcataccata tttttgaaaa aaagtgagaa aaaaggctta taattggagt ggtagttaat
      181 tagtgactta tttttgattt tatagcactg atactataaa atatagatat catcatatta
      241 cacaatctta atactaactt aaaaaatatc tcctttcata agtatggtga taaaatccgt
      301 tccgggctac ctttttaggt agcctacttt aatctttgta tctttctgga tcaacgaaag
      361 tatactttat atagtcataa cgccgatgat cgcttcgagc gtctagcaca tcagtcacga
      421 tatcaaacaa aaaatatacg tctttcttca ttctagtttt cgcagcaggg attttaaagt
      481 agttcttatt agaatagtag agattaatta ataagctatc ttcgattgct aaaaagaaaa
      541 cttctgaatc ccacacctta taaaaatctt tgacaaatct attcgaagga tcaaatttaa
      601 accataattg cgtctcatta aaaagcataa ccattactcc gatctatttt taaacttagt
      661 ctctacctct aatatatatc gagtttttat tttgccttca gagaatactg tttctttttt
      721 tgcagttaca ggttgtttat tttcggaaaa agctaatata gctaaaattg aaacatccat
      781 ctggaatttg tctttttcgt tgctttgctc ataaaaatct gcatattcat cactaatatt
      841 ttttctaata aattcttcca tcataaagat cacctcgaaa agagtatacg aacaaacgtt
      901 ctttttgtaa aggtggaatt tattatacta aataaatagg tgaacaagta cttgtgccaa
      961 attatgtgcc aaaaaaaatc gaatttaata aaacacaaac aaaaagaaat cctattatga
     1021 taacatttct tataataaca aacacaacag aagacgtgta atagttagtc aggaacgtac
     1081 aaataacccc tgtatccttt gcggtacagg gggttatttt gtataagtag acattgtagt
     1141 ttctaaactg ctatgtccta aacgtttcga tacgctaagt atatttactc cttgataaag
     1201 taaaatagat gcatgcgtat gtcttagtcc atcaataaac agtcgaagag aaaataggga
     1261 aaaattgatt actaaagaaa aacttactag gtcgacggtg tagttgattt tcatacttca
     1321 atagattcga attaaacgat ttcgattggc ttataccagt cctatccaac gaaagatata
     1381 tcgttcttaa ctctagcggt ataacttgaa gctttacgta aagccaatgg gaatgaactg
     1441 gagatgactt tttattattt ttagtaatag ctgatgggtt aatacttaca actttccttt
     1501 tcaaagtacc atataaaaa
//
LOCUS       DAFEKH010000153         1500 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.164, whole genome shotgun sequence.
ACCESSION   DAFEKH010000153
VERSION     DAFEKH010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1500
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.164"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            316..570
                     /locus_tag="LP386_002981"
     CDS             316..570
                     /locus_tag="LP386_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL1920141.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEDNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            571..888
                     /locus_tag="LP386_002982"
     CDS             571..888
                     /locus_tag="LP386_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBL1920142.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
BASE COUNT          531 a          228 c          290 g          451 t
ORIGIN      
        1 acaaaataaa aaggcaatac gccttagttg tcggtcttcg agttaccaac ggtaaccctc
       61 ataccgaacg gcattcatca cccacctata gaggatgggc gacttctgcc taattctgtt
      121 aaatggatgt taacggaagt gtatggtgag tagttcactc gtattttgat atcgtttgta
      181 tatgttttca gcgttctaag tggcttattt tgtccaataa taatatggag tggaatccct
      241 taagaaacac cgttggcaat tgttgttata acatgttata atttattcat caaaaactaa
      301 aaggagtgtg ataacatggg aaaagaacta aaggttagaa agatcggcaa tagcgtggga
      361 gtgatccttc caagctctct tggattaaaa agcggagaca ttatccaagc caaacaagaa
      421 gacaacttat tcatattaga tactactcaa atagcaaaag aacacgatcg caaattgatt
      481 gaagaaagtt tccaagactt tgagaaaggt ttaacagttt cagaaattga aatggtaaaa
      541 gctttcggaa aatacggctg gagtgaatag atgaaagagt acacgctagt ttattctaaa
      601 agttttcaga ccagccttga aacgataata gaagaatggg aaaatgagct tgctctttct
      661 ccagccagca taaaaagatt tgtaggtgcg atccagaagg ctttagaact aaccaaaaat
      721 tttccaacta tgcatgagga agtttccgaa atctatggaa tggatatccc aacatatcgg
      781 atcgtgatcg gcaaaagcta tgccttattt tatcggatcg accatgaaaa aaaagagata
      841 cttgtaggac gtattttcca atctaaacaa atgaaactag gcttttaaca ataattagga
      901 aaaagtcgct catcctctac aggtgggtga ttaatgccgc tcgatatggt tgttaaccgt
      961 cggttactcg aagattgata tataagactt agtacctttt tattttgctc catgttatgg
     1021 ccgaaggtct aaagatacaa tcattagtct agagaaaaat taagaacctt aggaactacg
     1081 gggatcgctt ggtgaataag agacactgct attagtgaaa aaataagata tcaagtacgc
     1141 tctattccca aaaatttcgt gactttactc atgagaggtt caagtagtat atttttaatc
     1201 aaaattgacg taacttttaa taaatactac ctaaataagg tagtatttat ttttgtgttt
     1261 taaaagagga agtccaatat atctatggga aacttcttaa atattatgtt ggtacatgaa
     1321 aatatacttc cctgctagac tatttacaac attttacttt gtacgtattc ttgttttaaa
     1381 aggaatggga taaaatatag gtacaataac tatttgatgc taaatataat taatggagga
     1441 gagatagtga acatacttaa tgaaaaaaga tatgtatggt ttgctggtaa aaaatatatt
//
LOCUS       DAFEKH010000154         1457 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.166, whole genome shotgun sequence.
ACCESSION   DAFEKH010000154
VERSION     DAFEKH010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1457
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.166"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            109..1041
                     /locus_tag="LP386_002983"
     CDS             109..1041
                     /locus_tag="LP386_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HBL1920143.1"
                     /translation="MLKLKEKEYIIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGL
                     LNKLTISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITE
                     EKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKEL
                     YANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEP
                     MDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLD
                     EIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            1113..>1457
                     /locus_tag="LP386_002984"
     CDS             1113..>1457
                     /locus_tag="LP386_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920144.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQD"
BASE COUNT          640 a          169 c          228 g          420 t
ORIGIN      
        1 gatgaaataa atcaaaagta tgatgaaaca ttaaaaaatg tctattcttc acttatcgtt
       61 tcaaatatag aagaaacttc atcttctgaa ataaaaaata agctttcttt gttaaaatta
      121 aaagaaaagg aatatattat tgacgatgct gtttctgtcc ctcttatttt aaataaacga
      181 gagaaaaata atttaaagaa aaaaatgctc attccatttg attcagaagt gaaaggatta
      241 ctcaataaac taactatttc taatatagac tcgactaggg aaaaaatcat aaaaatattt
      301 gataaaatta ataatttatt caagaatgac aatgctgaat taaggaaggg tcttttagag
      361 tttaaacttc aagaactaga acttcattac tcttatttag tgaaaattac cgaagaaaaa
      421 gaacaacaaa aagcaataaa agaacagatg atagaagagg aaaaagttcg tagagaaatt
      481 gatcgtgaaa agaaacgtat tgataaagaa caacgtcaat tcaattctga aatttccaaa
      541 ttaatcgcat atatgcaaaa agctaatgca gatgtggaaa aagaattata tgcaaataaa
      601 attcaagaac tggaagaaaa attaaaagaa ttagaagtta tacgtgaaaa tgtattacaa
      661 agagaattaa atactagagc cggttatgtg tatgtaatta gtaatattgg gtcttttggt
      721 gaagacatat ataaaattgg tatgactaga agattagaac ctatggatag aataaaagaa
      781 ttgagtagtg catcggttcc atttgaattt gacgttcatg cgatgatttt ttcagaggac
      841 gctccgtctt tggaaactaa attgcataat cattttagaa aacaagaagt taataaaatt
      901 aatcaaagaa aagaattttt caaagtttca ctagacgaaa tagagaaagt tgttttagaa
      961 aattataatg gaacagtaac atttacaaaa ttagctaaag ctgaacaata tagacgatct
     1021 ttagaattgt caaaagatta aatatataaa aagccttcgg gctttttctt ttaacaatta
     1081 ataggaacgt atattcgaaa ggaatagaaa taatgtggtt agaaaaaata aatgacaaaa
     1141 aatttaagta caccgaacgt tatacggatc ccttaactga aaaaaagaga aaagtgtccg
     1201 ttactttatc tagcaattca cgccaagctt ggaatcaagc taacttactt ttgaatgaaa
     1261 aaatcgcaga aaaaataaaa cgaaatgaag aattaccact aacttttgga gaattaaaaa
     1321 ctaaatggga tgaaaaatac aagccaactg taaaagaaag ttcctatcga acaactcagg
     1381 tttatctatc attaatttca aaatatataa aagatgatgt acttgtaaaa aacgttaata
     1441 gtaatcttat acaagat
//
LOCUS       DAFEKH010000155         1451 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.167, whole genome shotgun sequence.
ACCESSION   DAFEKH010000155
VERSION     DAFEKH010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1451
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.167"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            105..1406
                     /locus_tag="LP386_002985"
     CDS             105..1406
                     /locus_tag="LP386_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBL1920145.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT          476 a          293 c          264 g          418 t
ORIGIN      
        1 gatagaaaat cattctatcg gtcccttttg agcatgaaaa aacaaaacat acagaagctc
       61 cgttagaatt gaatcaccac aacacaatca aaggagcgtt ctgtatgcct gatcttcatc
      121 atatcaaact actacttgga atcaaagata aaaacatttt catcacaaat gtggaatcga
      181 agagcattaa gaatatcaag agtcttgttg tttctgcgac gttaagtaaa gaaattcgtc
      241 gctgtccttt gtgtaaacag atgaatcatg aaggcatgat cgttaagaac ggaaagaaaa
      301 aatcgctcat tcaacttaat aaatgtgcga accaactgac ttatcttgct ttagcgaaac
      361 aacgctacca ctgtcgtggc tgccacacct attttacggc gaatacctac attgtcgata
      421 gaaactgctt tatcgctaaa caagtgcgct ataaaatttt agaagagcta actgaaaaac
      481 aagcaatgac gacaattgct aagcattgcg gcgtttcttg gtcgaccgtt tctcggacac
      541 tcgcttctct gatccccatg acaaaagtaa aaagaaattg gttaccgcgt tgtttattaa
      601 tggatgaatt tcgttcactg aaaaatcaag tcggtcccta ctccttttct tgtatggatg
      661 gcgatactgg aaaattactg gatattcttc cttcacggaa gaaaaaggct ctcgtttctt
      721 attttatgca atttgaacga cgcgcacgat tgaaggtaaa ggtcatcgtg acggacatga
      781 atgtttctta tgcctctctg ataaaggaat gttttccaaa ggcaaaactc gttgtggatc
      841 gttttcacat tgtcaaacat ctcattcgta aatttgagga tattcgcgta cgaatcatga
      901 aaagctttga tcgaaacgat ccaacacaag ccaaatatta tcgacaatta aaggcgttgt
      961 ctcggcttct gatcaaacga caggacaagc ttgtttatga caaatggacc aaatggcgca
     1021 attttggttg ggcgtatctc accgaaagtg aagtggtgga tcgtctgctt tcgatctctg
     1081 acgaattacg aatcgcctat ttttactatc aagaaattct tcaagcgttt cacgacaaag
     1141 aggcggacac tttctttaaa cttgtaagaa cgatgcccaa ttccgttcca aaagaactgc
     1201 attctataaa aaaagctttt ataaactatg aatccggcat tcgtttagcc ctcgaattgc
     1261 cttattcaaa tgccaaaata gaaaatctgc atacccacat caaagcattg aaacgagtcg
     1321 cttatggctt tcgaagcttt cggaaaatga agaccagaat tttcttacta aataatctga
     1381 ttacctatga atcaaaaaac atctaaagta gaaaaggaat tctaccttag atgttcttat
     1441 ctcactctat c
//
LOCUS       DAFEKH010000156         1424 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.168, whole genome shotgun sequence.
ACCESSION   DAFEKH010000156
VERSION     DAFEKH010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.168"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(150..1337)
                     /locus_tag="LP386_002986"
     CDS             complement(150..1337)
                     /locus_tag="LP386_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HBL1920146.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DAFEKH010000157         1375 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.169, whole genome shotgun sequence.
ACCESSION   DAFEKH010000157
VERSION     DAFEKH010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1375
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.169"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            56..1351
                     /locus_tag="LP386_002987"
     CDS             56..1351
                     /locus_tag="LP386_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBL1920147.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFKLRIMIRHGKTFLTK"
BASE COUNT          432 a          274 c          262 g          407 t
ORIGIN      
        1 acaccctgaa atcctttaga attaatttgg ctaccaattc ataggaggat tcaagatgtc
       61 tcatactcag cttatcaaag ataccctaaa tattctagac ctaaatatct atttcgagga
      121 aaattgttta actaaagaaa aatacaaagg gcaaatttgc ttgatttaca aaggaactct
      181 tctgtacaag ccagaagagt gttcccattg tctttgtgtc gtcccctcta ggatcattcg
      241 ttgggggacg acaaccgttc ggttgttact gaatgatgtg tctgagtatc gcacttatct
      301 ggagctgaag aaacaacgat ttaaatgtaa gtcttgccaa agaacattcg tagcggatac
      361 ctctgttgct gaaaaacact gtttcattag tcaaaaagtt cgttggtctg tcattgctcg
      421 cttaaaagag aatacttcca tgacggaaat cgctcgtcag aaaaatattt ccacttcttc
      481 ggtctatcgt gtcatgaagc gattctaccg cccattgaat cctttcaaac agactttgcc
      541 aaaggtctta tgctttgatg aattcaaatc ggttcgaagt gttgccagtg caatgagttt
      601 tatcatgatg gacggacaaa gccatgcatt attggatatt gtcgaaaatc gacgcttgcc
      661 ttatttagaa cgctattttt ctcggttttc attagcgact cgtgaagccg ttcaattgat
      721 tgttattgat atgtatgcgc cttatgtttc gttggtgaaa aagcttttcc cgaatgctca
      781 gttgatcatc gatcgtttcc acatcgtcca acatattggc agaactttct tgaatcatcg
      841 agtgaaagaa accacggtac gacttaaagg aaattcccac tctcaacgag ggttagggaa
      901 aaaattgaag cgctattgga aactcctaca aaaagaagaa gcaaagttaa actatgaaaa
      961 acgggtttgg cgtgccagtt ttaaagatta tttgactgaa agtgagattg ccgatcgact
     1021 gttagctgct tgtcccaact tacgccaagg ctatcagtta taccaagaca ttctttatgc
     1081 ggtaaagaaa agagatcagt cactatttga ggattgttta actagagaca ttagcggtct
     1141 gccagaaacc tatacaacca ctttacgaac gtttaaaaag tttctgccac agatccaaaa
     1201 tgcgcttcac tacagctatt caaacggacc attggaatgc ttaaacaacc acatcaaagt
     1261 attaaaacgc aatgcgtacg gctttcgcaa cttttacaat ttcaaactac gaattatgat
     1321 tcgtcatggc aaaacatttt taaccaaata aacagaacag aaagaggttt tcttc
//
LOCUS       DAFEKH010000158         1368 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.170, whole genome shotgun sequence.
ACCESSION   DAFEKH010000158
VERSION     DAFEKH010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1368
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.170"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            82..>1368
                     /locus_tag="LP386_002988"
     CDS             82..>1368
                     /locus_tag="LP386_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HBL1920148.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQLIN"
BASE COUNT          467 a          263 c          257 g          381 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atcaatcaat taatcaat
//
LOCUS       DAFEKH010000159         1313 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.171, whole genome shotgun sequence.
ACCESSION   DAFEKH010000159
VERSION     DAFEKH010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1313
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.171"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            96..>1313
                     /locus_tag="LP386_002989"
     CDS             96..>1313
                     /locus_tag="LP386_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBL1920149.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADT
                     SVAKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTP
                     LPKVLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREA
                     VEWIVIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQK
                     HYQLGKQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQ
                     LYQDFLYAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPL
                     ECLNNHIKVLKRNA"
BASE COUNT          429 a          270 c          239 g          375 t
ORIGIN      
        1 accagcatct tttttatttt ccaaaacata tagaaaagac accttgaaat cctttagaat
       61 taatttggcg aaccaaccca aaaggaggaa tcaagatgtc ttacactcac cttatcaaag
      121 aaacattaga tattctagac ttatcagtta cttttaacga aaattgtctc acaaaagaaa
      181 aatacaaagg gcaaatctgt catatttatc gtggaaactt gatttataca gcccaagaat
      241 gcatccactg taaacaccag attgcttcag atattgtgcg ttggggtaca acaaccgtcc
      301 ggttgttaat gaacgatgtt tctgaatacc gtacctacct cgaattgaaa aagcaacgct
      361 tcaaatgcaa agcttgtcag cggacctttg tcgcagatac ttctgttgcg aaaaaacatt
      421 gtttcatcag tgagaaagtc cgctggtctg tcgtgactcg tctgaaaaaa aatacctcaa
      481 tgacagagat cgccgctcag aaaaatctat cggtctcttc tgtttaccgt attatgaagc
      541 gattttatcg tccgttgaat ccttttcgga caccgttacc taaggtactt tgttttgatg
      601 aattcaaatc agttcggggt gtttcaggtg ctatgagttt catcatgatg gatggacaaa
      661 cacagcgctt attggacatt gtcgagaacc gacaactgcc ttttttaaaa cgttatttta
      721 gtcatttttc acgagaaatt cgtgaagcgg tcgaatggat cgtgattgat atgtacgctc
      781 cttatgtatc gctcgttaaa aagctgtttc caaaagcaca gctgattatt gaccggtttc
      841 acatcgtcca acatattggt cgtacctttc gcaatcatcg aatcaaagaa acgaaccaac
      901 tattaaaaag caaagaacaa aaacactatc aattaggtaa gcaattaaaa agatactgga
      961 aacttcttca aaaagatgaa cgcaagcttg attatactcg acgcctttgg cgacctggct
     1021 tcaaagctca tttaacagag accgatattg tggatcgctt actgaaaggg agccctgctt
     1081 tgcgtgtagg ctatcagtta tatcaagact ttctttacgc tgtaaaggaa cgagactacg
     1141 tatcgtttga agaactactt accaataata tcatgcttcc cgaaggctat cagacgacct
     1201 tgagaacgtt ccagaaattt ctgccacaaa tcaaaaatgc tttacaacaa agttattcaa
     1261 atggcccact tgaatgtctg aacaaccata tcaaagtgtt aaaacgaaat gca
//
LOCUS       DAFEKH010000160         1294 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.172, whole genome shotgun sequence.
ACCESSION   DAFEKH010000160
VERSION     DAFEKH010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.172"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..1244
                     /locus_tag="LP386_002990"
     CDS             <1..1244
                     /locus_tag="LP386_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBL1920150.1"
                     /translation="ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCL
                     THYQHTYCCKSCEKEGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQE
                     NYWKQTHGLDISRDNITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESA
                     KTDTYYWQFCTGKDSQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESV
                     RLVYCFAHVRRKFFEAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQ
                     QELRPLFIAFYEWMATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERN
                     IKELVIGRKNWLHSTSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLS
                     AETLDQLLPWNKDVQQHFSRN"
BASE COUNT          423 a          233 c          277 g          361 t
ORIGIN      
        1 ctataacaga gaaagaacat ctccttcctt tggaagaaca attttgtgaa cattgcggtt
       61 cacagatgaa agatatcgga cggacaaaag tacgagaaga aattcgtttc catcaggcta
      121 tgttggattg tctcacccat tatcaacata cctattgttg taaaagctgc gaaaaagaag
      181 gactttcttc ttttaaaaaa gcgatcgttc ctaaaccttt gatttctaat agcttaggtt
      241 ccaatagttt agtggcggaa acgatccgga tgaaatttgg tcagaaagtt cctgcctatc
      301 ggcaagagaa ctattggaaa caaacacatg ggttggatat ttcgagagat aatatcacca
      361 attggcatat taaagcagtg caaaacgcgt tagacccttt aggagaacga ttaagagtct
      421 atcttaatca agaagagatt ctacacgggg atgaaacaag ttatcgtgtg attgaaagtg
      481 ccaaaacaga tacctattac tggcagtttt gtacaggaaa agacagtcag catcccatcg
      541 tttattatca ccacgacgaa agtcgtgctg gagatgttcc gaaaactttt ctcaaggagt
      601 ttacagggta tttacactgt gacggctata gcgggtataa tgccgtggaa agtgtacgac
      661 ttgtctattg tttcgcgcat gttcggcgga aatttttcga agcaattcca aaaggaaaga
      721 aaaacacgga tattcccgca gctcaagcag tcaaacaatt ggataaatgg tttgtcctag
      781 aaaagaaatg gaaagacttt tctcctgaga agcgattaag ctgtcggcaa caagaactgc
      841 gtccattatt tattgctttt tatgagtgga tggcaacgat agatcctgtt gcaaaatcca
      901 agttggatgc agccgttcaa tatgcgtgta aactacgaag tggttttgaa cctatttttg
      961 aagatggtcg tttagaactc acaaataatc gtgcggagcg aaatatcaaa gagctggtga
     1021 taggacggaa aaattggttg cattccacaa gtcttgaagg agcacgaact tcaggaatca
     1081 ttctgagtgt atataaaaca gcagaactta acggattgaa tcctgtaaag tatctagagt
     1141 ttctatttga taagatacca aatcttcccg tactttcagc agaaacttta gatcaactgt
     1201 tgccttggaa caaggatgta caacaacatt tttctcgtaa ctaaaaacgc caaacattcc
     1261 cgattctatt ctataggtcg ggttatttga cgta
//
LOCUS       DAFEKH010000161         1193 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.173, whole genome shotgun sequence.
ACCESSION   DAFEKH010000161
VERSION     DAFEKH010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1193
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.173"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..1076
                     /locus_tag="LP386_002991"
     CDS             <1..1076
                     /locus_tag="LP386_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBL1920151.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          210 g          331 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tct
//
LOCUS       DAFEKH010000162         1137 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.174, whole genome shotgun sequence.
ACCESSION   DAFEKH010000162
VERSION     DAFEKH010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1137
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.174"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            75..692
                     /locus_tag="LP386_002992"
     CDS             75..692
                     /locus_tag="LP386_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920152.1"
                     /translation="MVKVKRMMETDESGVKRQFMPITHVSAVLGLEKMISGQSKVLSV
                     NGKYGAVILTKADLGLENAITELPYASETSDGILTAEMFQKIVNGEGGTYILPIATPE
                     QLGGIKVGELLEVTEEGVLSATKQTDFNFSEELKGKLESLKILKAGANISIAEDGTIS
                     STGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            696..>1137
                     /locus_tag="LP386_002993"
     CDS             696..>1137
                     /locus_tag="LP386_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920153.1"
                     /translation="MTDIVKIKQSGVQVYPQTHWNAIEGKPTTVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKVKLDGLANITFEKVG"
BASE COUNT          413 a          167 c          253 g          304 t
ORIGIN      
        1 ggagctttga ttattgcaac tgttgatgat ccaaaacaga atgttttcac tcttgagaaa
       61 gttggggtga tttgatggtt aaagtaaaga gaatgatgga gactgatgaa tctggtgtta
      121 aacgtcaatt tatgccaatt acacatgttt ctgcagtttt aggcttagaa aaaatgatat
      181 caggacaatc aaaagttctt tcggttaatg gtaaatatgg tgcagtcatt ttaacgaaag
      241 ctgatttagg attagagaat gcaattactg aactacctta tgcaagcgag acaagcgatg
      301 gtattcttac tgctgaaatg tttcaaaaga tcgtaaatgg agaaggtgga acatatattt
      361 tgccgattgc tactcctgaa caattaggag gtataaaagt tggggaactc ttagaagtta
      421 ctgaagaagg tgttttatct gcaactaagc aaacagactt caatttctct gaagaattaa
      481 agggaaaatt agaatctcta aaaatattaa aagcaggtgc aaatatatca attgcagaag
      541 atggaacaat tagttctaca ggtggtagtg ggactggtgg tgttaatcag tcatatgtag
      601 atcaaaaatt ccaagaagct gtaaatcaag cagaaaatta cacaaacgaa agaattccaa
      661 attttacttt tgaaaaaatc ggggaggtat agaaaatgac agatatcgta aaaataaaac
      721 aaagcggtgt acaggtttat ccacaaactc attggaatgc tatagaaggc aaaccaacaa
      781 cggtgaaggg agataaaggc gatcctggcc aagcagcaac aattaccata ggaaccgttt
      841 ctagtggttc aaccgcttct gttacgaatg taggaacatc atctgcagct agatttaatt
      901 ttgttttacc aaagggagat aaaggtgatc ctggaataaa tgccacaact acagctgtag
      961 ctacaactac agcaaatggg ttgatgtcgt ccacagataa aactaagttg gatggaattg
     1021 cagctggagc acagaaaaat ccaggtaatg ctacaactac gacagcaggt ttaatgtcag
     1081 caaccgataa agtgaaactt gatggattag cgaatattac atttgagaaa gtgggga
//
LOCUS       DAFEKH010000163         1058 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.175, whole genome shotgun sequence.
ACCESSION   DAFEKH010000163
VERSION     DAFEKH010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1058
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.175"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(36..992)
                     /locus_tag="LP386_002994"
     CDS             complement(36..992)
                     /locus_tag="LP386_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920154.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          344 a          176 c          160 g          378 t
ORIGIN      
        1 tagaaaaagc agtcggactt tctaaaagaa gttcactatt cgatcctgtc gatgatttct
       61 tcaggaaaat cgtctatttg cttgtcaatt ttgctgtctt tgtatttctc ttcttggata
      121 gtcaacaaaa tctttgtaag attcccccag tctactgctc ttggcggatc gagccaaacc
      181 actacttgag atgcactttc ttcatataga ttattcctat tcgtgattat aacatccggg
      241 aactcaggct ttcctgcctc tatcacttcc gtgttcagat taatgtacaa gcttaaattt
      301 ttcttgataa attgattata ggcagcacca taagaaaaat cgatgatgat ctttactggt
      361 tcagaaatca gttgaatggg tatgtgattg atcaataata ataaataact gaaaaaaaga
      421 aaaaatttat cttgaagcaa ctctttgcgt tttgacgtta gatcatttat atactctatc
      481 aaatagcaat aaaatgctgg atagttttct ctaaaaaaag aaacatcaag tggaaattca
      541 tcagctttat taatagtgta atgcaaaagt ttaaaatgta ttttggttaa ctctcttcgg
      601 atcaattggc tcgtctcttc tcgcaacaga ttaaactgat tttcaaaact ttcaatgaat
      661 cgttcattca accattcgat tgtttcatct tcattttttc tcaagtattt ttgatccaat
      721 ttatcatgaa gataaagcca agagagtgtc ttattgataa aaataacgga tttttctcct
      781 aatactcctt ttaagtggta aaatcctata tccgaaaaaa atagcgactg attgctagca
      841 atatctaaag aatcagcttg ttcagccaac aggttgattg ctaaaaagtg gaataatttc
      901 tttttttcat aagcagacag aggataatac tgttttaaat cttttaacat tttttctgtt
      961 tttataatta taggtagcgt atacaattcc acaaaactta tctctgttga gttaaaaaga
     1021 ttatataaaa aaagccgaat gtttttagga ttccctgt
//
LOCUS       DAFEKH010000164         1045 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.176, whole genome shotgun sequence.
ACCESSION   DAFEKH010000164
VERSION     DAFEKH010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1045
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.176"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..203
                     /locus_tag="LP386_002995"
     CDS             <1..203
                     /locus_tag="LP386_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBL1920155.1"
                     /translation="IYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFDTYNQK
                     FLNRSHKGFQQVTDTLVSMFTE"
     gene            256..1038
                     /locus_tag="LP386_002996"
                     /pseudo
     CDS             256..1038
                     /locus_tag="LP386_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
BASE COUNT          438 a          154 c          137 g          316 t
ORIGIN      
        1 ccatttactc aaccaatcta atcgagtctt tcaataagca aattaaaaga tacagccgta
       61 gaaaagagca gtttcaaaat gaagaatcac tagaacgctt tctagtcagc atttttgata
      121 catacaatca aaaatttcta aacagaagcc ataaaggttt tcaacaggta accgatacat
      181 tagtttcaat gtttactgag taactaatta ttttgcagga ggacaattta tttacacaaa
      241 attattgacg ctccccaaga tatgctagat tactactatt ttgaaaaaaa tttatcatat
      301 aattatgtaa tacatttaaa aacttttaca ggaatgattt ttaaattcgc caaccgtcga
      361 tatggattaa aatataatcc cgtaaatggg gtttctttag caagaaaacc taagacaaac
      421 gaagaaataa aaaaagaaaa agatggttat ttatcaaaag aagaagttca aatgattgct
      481 agtaaacaaa aaagttcaca tcaacagtca cgttattctt taattactaa atttttgttt
      541 ttaactggac tacgttatgg tgaattgata tctttgactg aatctgatta tgatggtaat
      601 aaaattacgg tttctggtac ttatgattac gagttaaaaa ttaaaacaac aactaaaaat
      661 acaggttctt atagaaccat tgaattatca agtaatgcta aagaaatcat agatcaatta
      721 attgaagaaa acaaattaat taagaataat aaagataaat acattttcat ctctaaaaat
      781 ggtaacccga tatctattca agcatataat caatctttaa gagcagtatc caaagaatta
      841 aacatagata aaaaagtttc ttctcacatg ttaaggcatt cccacatttc tctacttaca
      901 gaattaggaa tcccattaaa agccattatg gatcgtgtag gacatgaaga ttcaaaaaca
      961 acattaaaga tttatactca tacaactaaa aatatgcaaa atcaactagt agaaaaacta
     1021 ggaaaaatag aaatttaaat tgccc
//
LOCUS       DAFEKH010000165         1028 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.177, whole genome shotgun sequence.
ACCESSION   DAFEKH010000165
VERSION     DAFEKH010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1028)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1028)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1028
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.177"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..929
                     /locus_tag="LP386_002997"
     CDS             <1..929
                     /locus_tag="LP386_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HBL1920156.1"
                     /translation="FNLGANEGSSQVANNQYILLHETANETATGRNEAQYMQRSWTSA
                     YTAYIVGDGGIVYQVGQPGYVQYGAGSYANANSPVQIELQHTHDKATFEKNYKAYVEL
                     ARDSAMKYGIPLTLDTPYNQPGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKLAYDL
                     AHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNYAHIDQFGEIENANLHVAGWHIA
                     NYKYEYIFIMDYNTGKELARVRADGIYRSDVNQAYNTSGNVGYHVSFNMRNFPNKKVY
                     VMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
BASE COUNT          354 a          187 c          208 g          279 t
ORIGIN      
        1 aatttaattt gggcgcaaat gaaggtagct cacaagtagc aaataatcag tatattttac
       61 tgcatgaaac ggctaatgaa acagcaacag gacgcaatga agcgcagtat atgcaacgtt
      121 catggactag cgcttatact gcttatattg tgggagacgg cggaattgtt tatcaagtcg
      181 gtcaacctgg ttatgtacag tacggtgctg gttcgtatgc taatgccaac agtcctgtgc
      241 agattgagtt acaacacaca catgataaag caacgtttga gaaaaactac aaggcatacg
      301 ttgaattggc tagagattca gcaatgaaat atggtattcc attaacgttg gacactcctt
      361 ataaccaacc gggaatcaaa tcgcatttat gggtaacaca aaacatctgg ggcgatcata
      421 cagatcctta cggttatctt tctgaaatgg gcgtaagtaa agaaaaatta gcatatgatt
      481 tagctcatgg atttaccgat gaaaatccaa caacttctga aaacaagcct gtcattgatc
      541 caacacgagc tggtgcagct aatcctacac tgacagatgg aacgaattac gcccacattg
      601 atcagtttgg agaaatcgaa aatgcaaatt tgcatgtagc tggatggcac attgctaact
      661 ataaatacga gtatatcttc attatggatt acaatactgg gaaagaatta gctcgagtaa
      721 gagctgatgg aatttataga tcagatgtaa atcaagctta taatacttct ggaaatgttg
      781 gctatcatgt atcttttaac atgcgtaact tccctaataa gaaagtctat gtcatgatgc
      841 gggcaacgaa tgatccagag ggaaacacta aaggcggtgc gcaagatttc catgacaaac
      901 gttggtattt aaatattcct aaacgataaa aatagctcct cgttgaggag cattacataa
      961 ctatattgac aactataaaa atcattcgat aaaatagtga tgttatcgca tatcttcact
     1021 atcaccca
//
LOCUS       DAFEKH010000166         1017 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.178, whole genome shotgun sequence.
ACCESSION   DAFEKH010000166
VERSION     DAFEKH010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1017
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.178"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            512..>1017
                     /locus_tag="LP386_002998"
     CDS             512..>1017
                     /locus_tag="LP386_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element ISS1D family transposase"
                     /protein_id="HBL1920157.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWVQEYSKVLYYLWKKKNRQSFYSWKMDETYIKIKGRWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFRKLQSVGLYTKTEHRTVK
                     YLNNLIEQ"
BASE COUNT          353 a          161 c          182 g          321 t
ORIGIN      
        1 acacaaaatt attgacgctc ccaagctaaa actcctatta atcgatctac taaaaataaa
       61 taaaaaaatt cttttcaatt ttatttatgg tatgacataa ataaagtaaa gttattcttc
      121 taggttaatc ttattaatac tctttctcac tagtgttgca tgcaacacta gtgagaaaga
      181 gtattaaata tactgcaagg caagacattt ggtaattgaa gaataacaag caaaaaaata
      241 gcagtcaggt ctcttgacaa agtatagttg ctattctttt tttaggccct actttaatga
      301 aatttttgtt tggagggaac gacttcattc ctttgattat ttcagttgaa tttaatagag
      361 aagcctggcg tctattaaga aatacttttc ttgatgagcg tcaatttttt taacggaaat
      421 ctatcctata ctaaattcgg ttctgttgca aagttttcca aaaaatctat tttagtgtaa
      481 aattgagaaa aaagacagag aggacagagt aatgaatcat tttaaaggca aacaattcaa
      541 aaaagacgtc attattgtcg ctgttggtta ctacctgcgt tacaatctaa gctatcgtga
      601 agttcaggaa ttgttatatg atcgtggaat aaatgtttgt catactacga tttatcgttg
      661 ggtgcaagag tacagcaaag tcctctatta tctttggaag aagaaaaata gacaatcctt
      721 ctattcatgg aaaatggacg aaacctatat caaaattaag ggacgttggc attatcttta
      781 tcgtgcaatt gatgcggacg gcttaacctt agatatctgg ttacgaaaga aacgggatac
      841 gcaagcagcc tatgctttct taaaacgact ccataaacag tttggtgagc cgaaagcaat
      901 tgtgaccgat aaagcacctt ctcttggctc cgcctttaga aagttacaga gtgtgggttt
      961 atatactaag acagagcacc gaactgtgaa gtatcttaac aatttaatag aacaaga
//
LOCUS       DAFEKH010000167         1000 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.179, whole genome shotgun sequence.
ACCESSION   DAFEKH010000167
VERSION     DAFEKH010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.179"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            369..1000
                     /locus_tag="LP386_002999"
                     /pseudo
     CDS             369..1000
                     /locus_tag="LP386_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          342 a          181 c          183 g          294 t
ORIGIN      
        1 tttcaaagtt agtagagaaa atgtagttat atatttaaat ttttaccaga aagaaatgaa
       61 caccttcaat tatctaaatc tcgaaaatgg ttagatgtaa tcatcaggaa aaacaatctt
      121 aaacgaatta ctattcatgg tcttagacac acacatgcta gcttgctttt agcaagctag
      181 tgcaaatatt aaagatgtgc aagagcgttt aggccactct tctattcaaa tcattatgga
      241 tctatatatt catattacag acaaaagaaa agaagaaacc gtagcgcaat tcgcaaaata
      301 taggctctat aatttatggg actgatgaat caaaattgat tcttcagtcc cattgttatt
      361 ttaggtatat gattcgtaca ttgaaagagt tgaaaaacta tcttccgaag ccgtcaaaaa
      421 ggaccctgcc aaaagtattg atggtggatg aatttcgttc gcacgcttca attgtggata
      481 aaatgagctt tatttgtgcg gatggcgaga ctggaaaact cattgatatt ttgcctacac
      541 gaaaattgtc tcgattaaca cactatttta gtcgctgtgc aaatcctgaa gcggtggaat
      601 atttagtgac agatatgaac gccgcctact tccaactgac aaaacgtgtc ttaccaaatg
      661 cgaaagtcgt cattgattgt tttcatatca tcaaacattt gaatcaggcg ttcaatgatt
      721 ttcgtgtaca agaaatgaaa agattacacc agttagggca acgacgggaa gccgagaaag
      781 tgaaaaagaa ctggcgcttt cttctaaaaa accgtcaaaa aatcaatcac tatgattaca
      841 aaacatggcg cagttttcgt gcacctaaat acccgctact cactgaagca atgatgattg
      901 atcgattgct ggcattttca acgcctttaa aggacgccta tacttttttc catgagctga
      961 ccgaagcctt tagagacaag gaatcagact tattttttac
//
LOCUS       DAFEKH010000168          996 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.180, whole genome shotgun sequence.
ACCESSION   DAFEKH010000168
VERSION     DAFEKH010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..996
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.180"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..>996
                     /locus_tag="LP386_003000"
     rRNA            <1..>996
                     /locus_tag="LP386_003000"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          268 a          227 c          301 g          200 t
ORIGIN      
        1 gaaataatag taccgaagtt cctgatgtca cactgccgag aaaagcttct agtgagaaaa
       61 cagcggcccg taccgcaaac cgacacaggt agtcgaggag agaatcctaa ggtgagcgag
      121 agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa ggggtgctga
      181 tcatacgatc agccgcagtg aataggccca agcgactgtt tatcaaaaac acaggtctct
      241 gcaaaatcgt aagatgaagt ataggggctg acgcctgccc ggtgctggaa ggttaagagg
      301 agtgcttagc gcaagcgaag gtacgaattg aagccccagt aaacggcggc cgtaactata
      361 acggtcctaa ggtagcgaaa ttccttgtcg ggtaagttcc gacccgcacg aaaggcgtaa
      421 cgatttgggc actgtctcaa cgagagactc ggtgaaattt tagtacctgt gaagatgcag
      481 gttacccgcg acaggacgga aagaccccat ggagctttac tgtagtttga tattgagtgt
      541 ctgtaccgca tgtacaggat aggtaggagc cgtagaaatc ggaacgctag tttcgatgga
      601 ggcgctggtg ggatactacc cctgcgttat ggccactcta acccgcacca ctaatcgtgg
      661 tgggagacag tgtcagatgg gcagtttgac tggggcggtc gcctcctaaa aggtaacgga
      721 ggcgcccaaa ggttccctca gaatggttgg aaatcattcg aagagtgtaa aggcagaagg
      781 gagcttgact gcgagaccaa caagtcgagc agggacgaaa gtcgggctta gtgatccggt
      841 ggttccgcat ggaagggcca tcgctcaacg gataaaagct accctgggga taacaggctt
      901 atctccccca agagtccaca tcgacgggga ggtttggcac ctcgatgtcg gctcgtcgca
      961 tcctggggct gtagtcggtc ccaagggttg ggctgt
//
LOCUS       DAFEKH010000169          992 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.181, whole genome shotgun sequence.
ACCESSION   DAFEKH010000169
VERSION     DAFEKH010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..992
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.181"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(21..94)
                     /locus_tag="LP386_003001"
     tRNA            complement(21..94)
                     /locus_tag="LP386_003001"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(58..60),aa:Ile,seq:cat)
     gene            complement(108..181)
                     /locus_tag="LP386_003002"
     tRNA            complement(108..181)
                     /locus_tag="LP386_003002"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(145..147),aa:Met,seq:cat)
     gene            complement(209..281)
                     /locus_tag="LP386_003003"
     tRNA            complement(209..281)
                     /locus_tag="LP386_003003"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(246..248),aa:Ala,seq:tgc)
     gene            complement(301..374)
                     /locus_tag="LP386_003004"
     tRNA            complement(301..374)
                     /locus_tag="LP386_003004"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(338..340),aa:Pro,seq:tgg)
     gene            complement(384..457)
                     /locus_tag="LP386_003005"
     tRNA            complement(384..457)
                     /locus_tag="LP386_003005"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(421..423),aa:Arg,seq:acg)
     gene            complement(468..553)
                     /locus_tag="LP386_003006"
     tRNA            complement(468..553)
                     /locus_tag="LP386_003006"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(517..519),aa:Leu,seq:taa)
     gene            complement(570..641)
                     /locus_tag="LP386_003007"
     tRNA            complement(570..641)
                     /locus_tag="LP386_003007"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(607..609),aa:Gly,seq:gcc)
     gene            complement(653..725)
                     /locus_tag="LP386_003008"
     tRNA            complement(653..725)
                     /locus_tag="LP386_003008"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(690..692),aa:Thr,seq:tgt)
     gene            complement(743..824)
                     /locus_tag="LP386_003009"
     tRNA            complement(743..824)
                     /locus_tag="LP386_003009"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(788..790),aa:Leu,seq:tag)
     gene            complement(832..904)
                     /locus_tag="LP386_003010"
     tRNA            complement(832..904)
                     /locus_tag="LP386_003010"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(869..871),aa:Lys,seq:ttt)
     gene            complement(908..980)
                     /locus_tag="LP386_003011"
     tRNA            complement(908..980)
                     /locus_tag="LP386_003011"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(945..947),aa:Val,seq:tac)
BASE COUNT          261 a          283 c          235 g          213 t
ORIGIN      
        1 tgaaacttac aacgccacaa tggaccttgt aggactcgaa cctacgaccg gacggttatg
       61 agccgtctgc tctaaccaac tgagctaaag gtccaggctc ttaaaaatcg cggcggaggg
      121 gatcgaaccc ccgacctccc gggtatgaac cggacgctct agccagctga gctacaccgc
      181 gaaaaagata ttcattattt aaatgaaatg gagcctagcg ggatcgaacc gctgacctcc
      241 tgcgtgcaaa gcaggcgctc tcccagctga gctaaggccc cgtgtttaaa tttataatta
      301 tcgggaagac aggattcgaa cctgcgaccc cttggtccca aaccaagtgc tctaccaagc
      361 tgagctactt cccgtttaat taacgcgccc aagaggagtc gaacccctaa ccttttgatc
      421 cgtagtcaaa cactctatcc agttgagcta tgggcgcata tttgaaatgc cgaggaccgg
      481 aatcgaaccg gtacggtgat cactcaccgc aggattttaa gtcctgtgcg tctgccagtt
      541 ccgccacccc ggcgcgattg ctttggcaaa gcggaaaacg gggttcgaac ccgcgacccc
      601 caccttggca aggtggtgct ctaccactga gctatttccg cgtgtttaaa gatgccggct
      661 aaaggacttg aaccctcgac cctctgatta caaatcagat gctctaccaa ctgagctaag
      721 ccggcatgta aaacttaaat tatgcgggtg aagggacttg aacccccacg ccgtaaggcg
      781 ctagatccta aatctagtgc gtctgccaat tccgccacac ccgcaaaaat atgagccgta
      841 cagggctcga acctgtgacc ctctgattaa aagtcagatg ctctaccaac tgagctaacg
      901 gctcatatgg aggttaacgg gatcgaaccg ctgaccctct gcttgtaagg cagatgctct
      961 cccagctgag ctaaacctcc atggataact ta
//
LOCUS       DAFEKH010000170          961 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.182, whole genome shotgun sequence.
ACCESSION   DAFEKH010000170
VERSION     DAFEKH010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..961
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.182"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            34..>961
                     /locus_tag="LP386_003012"
     CDS             34..>961
                     /locus_tag="LP386_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL1920158.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVFLSY"
BASE COUNT          342 a          174 c          185 g          260 t
ORIGIN      
        1 ttccgacgaa agaattataa ggagtgagta caaatgacct ataaccatct tacaccaact
       61 gaactcgtaa tgatagaagc ttatttcaat caatcacaac ctgtttcaaa agtagccaat
      121 ctgttacaac gttctcgaca aactatttat aaggtctatc gttttcttaa atctggtgga
      181 agcgcaatga gctactataa acaatataag aaaaacaaac gtaactgcgg aagacatccg
      241 attgttttac ctgatgagca acaggaatac attcaaaaaa aggttgttca agggtgggct
      301 cctgatgtcc ttattggtcg agcagagttt cctattgctt gttcggtacg cacactgtat
      361 cgaatgttta aagataaaac ctttgacact cacgatttac caatgaaggg aaaaagaaaa
      421 ccaaacggtc ataaagaaaa aagaggaaaa caagggtttc gccggtcaat ccgagacaga
      481 aagacagact atacccagtt tgatcatgaa tttggtcacc tggaaggtga cactatcgtg
      541 ggtggaaaac ataaaagcgc ggtcatcaca ttagttgaac ggctatctaa agtcatcatt
      601 accttgaaac ccgaaggcag acaggctaaa gacattgaaa ataggctgaa tcaatggttt
      661 cgttgtgtcc caaaaaactt atttaaatcc atcacatttg attgtggaaa agaattctca
      721 aattggaaaa agattagtaa taccaacgat atttcaattt attttgcgga tccaggaaca
      781 ccttctcaac gaggattgaa tgaacattca aatggcttat tacgtaaaga tggtttgtat
      841 aaagctatgg attttaatgg tgtatctgaa acctttatcc aatcggtggc atcgaaacga
      901 aatcatattc ctagaaaatc attacactat cggacaccaa tggaagtatt tttgagttac
      961 g
//
LOCUS       DAFEKH010000171          960 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.183, whole genome shotgun sequence.
ACCESSION   DAFEKH010000171
VERSION     DAFEKH010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..960
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.183"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..>960
                     /locus_tag="LP386_003013"
     CDS             <1..>960
                     /locus_tag="LP386_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HBL1920159.1"
                     /translation="HSIANHVRYKIASLLTEKVSLSFIAKNCQVSLTTVIRTLKEFKS
                     YLPKQSKRILPRVLMVDEFRSHASIEDKMSFICADGETGQLIDVLPTRKLPRLTSYFL
                     GCANPEEVKFLVTDMNAAYFQLTKRILPNAKVVIDRFHIIKHMNQAFNELRIREMNEL
                     RKVGQKSQAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLGFS
                     TSLKEAYPYFHELVEAFRDKDPDLFFSLLAELPETLDDGFREKLQNLLTYEEGITNAM
                     IYPYTNGKIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQLIK"
BASE COUNT          324 a          187 c          176 g          273 t
ORIGIN      
        1 cattcaatcg cgaatcatgt cagatataaa attgcttctt tactgactga aaaagtatct
       61 ttatctttta ttgcgaaaaa ttgtcaggta tctttgacca ccgttattcg tacgttgaaa
      121 gagtttaaaa gctacttacc aaagcaatct aagaggattc tccccagagt attgatggtt
      181 gatgaatttc gttcgcacgc ttccatagaa gataaaatga gctttatttg cgcagatggc
      241 gaaacaggac aattaattga tgtcttgcct acgcgtaaat tgcctcgatt aacaagctat
      301 ttcttaggct gcgctaatcc tgaagaagta aaatttttag tcacagacat gaacgccgcc
      361 tacttccagc ttaccaaacg tattctgcca aatgcgaaag tagtgattga tcggtttcat
      421 attatcaaac acatgaatca agcctttaat gagttgcgta tccgtgaaat gaatgaactt
      481 cgtaaagtag gacagaaaag tcaggcagaa aaactgaaaa agaactggcg ctttttgcta
      541 aaaaatcgtg caaacatcaa ccattatgaa tacaaaacat ggaaaagttt tcgagcacca
      601 aaatacccat ttcttacgga agcgatgatg attgatcgat tgcttggctt ttctacgtcc
      661 ctgaaggagg cgtatcccta ttttcatgaa ttagttgaag cctttcgaga caaagaccct
      721 gacttatttt tctccttatt ggcagaactt cccgaaacgt tagatgacgg ctttcgggaa
      781 aagctccaaa accttctgac ctatgaagaa ggcatcacca acgcgatgat ctatccttac
      841 accaatggaa aaatagaagc gaagaatacc catataaaga caatgaaacg agtatcctac
      901 ggatttaaat catttgagaa catgagaatt agaatctttt tgatcaatca attaatcaaa
//
LOCUS       DAFEKH010000172          916 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.184, whole genome shotgun sequence.
ACCESSION   DAFEKH010000172
VERSION     DAFEKH010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 916)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 916)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..916
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.184"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..>916
                     /locus_tag="LP386_003014"
     rRNA            <1..>916
                     /locus_tag="LP386_003014"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          284 a          183 c          268 g          181 t
ORIGIN      
        1 gtagacgcag agaactgaaa catctaagta cctgcaggaa gagaaagaaa attcgattcc
       61 ctgagtagcg gcgagcgaaa cgggaaaagc ccaaaccagc aagcttgctt gttggggttg
      121 taggactcca atatggtagt tctttcagat agtcgaatga cttggaaaag tcagtcaaag
      181 agggtaaaaa ccccgtagac gaaatgtgga agacacctag gaggatcctg agtacggcgg
      241 aacacgagaa attccgtcgg aatccgggag gaccatctcc caaggctaaa tactccctag
      301 tgaccgatag tgaaccagta ccgtgaggga aaggtgaaaa gcaccccgga aggggagtga
      361 aatagaacct gaaaccgtgt gcctacaaca agtcaaagcc cgttaatggg tgatggcgtg
      421 ccttttgtag aatgaaccgg cgagttacga ttgcatgcga ggttaagttg aagagacgga
      481 gccgcagcga aagcgagtct gaatagggcg tttgagtatg tagtcgtaga cccgaaacca
      541 tgtgatctac ccatgtccag gttgaaggtg cggtaaaacg cactggagga ccgaacccac
      601 gtacgttgaa aagtgcgggg atgaggtgtg ggtagcggag aaattccaaa cgaacttgga
      661 gatagctggt tctctccgaa atagctttag ggctagcctc ggaattgaga atgatggagg
      721 tagagcactg tttggactag gggcccatct cgggttaccg aattcagata aactccgaat
      781 gccattcatt catatccggg agtcagactg tgagtgataa gatccatagt cgaaagggaa
      841 acagcccaga ccaccagcta aggtcccaaa atatatgtta agtggaaaag gatgtggggt
      901 tgcacagaca actagg
//
LOCUS       DAFEKH010000173          884 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.185, whole genome shotgun sequence.
ACCESSION   DAFEKH010000173
VERSION     DAFEKH010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..884
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.185"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..882
                     /locus_tag="LP386_003015"
     CDS             <1..882
                     /locus_tag="LP386_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HBL1920160.1"
                     /translation="LDSRTRFEQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYYWV
                     KKLDKPDKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMGLT
                     CQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPILDL
                     FNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLKEN
                     NIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKRIK
                     LKLNGLSPVEYRKQSIK"
BASE COUNT          382 a          115 c          143 g          244 t
ORIGIN      
        1 cttgattcaa gaacaagatt tgagcaagaa gaaatcaagg ttaaaacaat ccttcagctc
       61 aaaaaagaat ttaaattgaa tctattactt tcaattgcac aattagcgaa gtcaacttat
      121 tattactggg taaaaaaatt agataagcca gataaatata gcaagataaa gcaagaaatt
      181 acagcgattg taaaagaatc aagaaactct tatggttatc gtagagtcac tttagcgtta
      241 aagatgaaag gatatacaat caatcataaa acagttagaa aattaatgtc ccaaatggga
      301 cttacctgtc aaatccgaat aaagcgatat aaatcttata aaggaacagt aggaaaaatt
      361 gccaagaatg tgttaaaacg aaatttttca gtagatacac ccaataaaaa atgggtgaca
      421 gacgtcactg aattcaagat aaaaggaaga aaaatctatc tatctcctat acttgattta
      481 tttaacggag aaataattag ttatagtata tcaactagtc caacatataa actgattgaa
      541 gaaatgcttc aacaagcaat taaaaaaaag ggaactgagg gttcactgat tctacattca
      601 gatcaaggat ggcagtatca gatgccacaa tatcaaaaaa aattaaaaga gaataacatt
      661 attcaaagca tgtctagaaa aggaaattgc ttagataatt ctgtaataga aaattttttt
      721 ggtgtgctta aatcagagtt tttttatcga gaaaaattcc gatcaattga gatatttcaa
      781 agtaaattaa atgagtatat taggtggtat aataacaaaa ggataaaact aaagttaaat
      841 ggactatctc cagtagaata tcggaaacag tccattaaat agtt
//
LOCUS       DAFEKH010000174          859 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.186, whole genome shotgun sequence.
ACCESSION   DAFEKH010000174
VERSION     DAFEKH010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..859
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.186"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            28..>859
                     /locus_tag="LP386_003016"
     CDS             28..>859
                     /locus_tag="LP386_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL1920161.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     V"
BASE COUNT          297 a          149 c          165 g          248 t
ORIGIN      
        1 ccaaagaatt ataaggagtg agtacaaatg acctataccc atcttacaac ggatgaactt
       61 gtaataatag agtcttattt caaaatgaat caatctgttg ctaaaactgc ccattgcttg
      121 aatcgttcaa gacaaacgat ccataaagta tatctgttct tcaagcaagg aaaatcagcc
      181 ttagaatatt atcaacagta taagaaaaac aaatcaaact gtggtagacg tccgcttgtt
      241 ttacccgagg aacaatcaga atatattcaa agaaaggttg ttcaaggatg gacacccgat
      301 gtgattgttg gtcgtgcagc gtttcctatt agttgttctg ctcgtaccat ttatcgtatg
      361 ttcaaaaagg ggctatttga ttcttctgac ttaccgatga aaggcaagcg taaaccgaat
      421 ggacatcaag aaagacgtgg aaaacaaact ttccgccgct ctattcatga acgtgaaaag
      481 gattatagcc aattctcaaa tgagtttggt caccttgaag gtgacactat cgtaggtctg
      541 aaacataaaa gtgctgtaat taccttagtt gaacgattat caaaagttat catcacattg
      601 aaaccgtgtg gtagacaagc gattgatatt gaaaaaaaat taaatcaatg gtttgaatct
      661 gtaccgaaaa acctattcaa atccatcact tttgattgtg gaaaggaatt ttcaaattgg
      721 aaacagatca gtaatgtcaa tgatattgcc atttatttcg ctgatccagg aacgccgtct
      781 caaagaggcc taaacgagaa ttctaacgga ttgttacgta gagatggttt attgaaatct
      841 atggatttca attcagtag
//
LOCUS       DAFEKH010000175          856 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.187, whole genome shotgun sequence.
ACCESSION   DAFEKH010000175
VERSION     DAFEKH010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..856
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.187"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            551..>856
                     /locus_tag="LP386_003017"
     CDS             551..>856
                     /locus_tag="LP386_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBL1920162.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     "
BASE COUNT          307 a          162 c          138 g          249 t
ORIGIN      
        1 actcctctta atatacagtc ctattgtata aagtgttact atatacatag taactgtata
       61 cataaaaaaa gtcaagtatt agaaaaaagt tcaaaagatc aagtgtgcgc ttcgctccca
      121 ctcccctcga cgttttagta gcctttccct cacttcgttc agtccaagcc aactaaaaag
      181 ttttcgggat acattctcct tctcttccta ataatcaatt aaaattttaa tctttatatt
      241 tctgctaatc actcaggaaa cagtacagaa aaacaaacac gtatcataga tataaatgta
      301 atggcatagt gcgggtttta ttttcagcct gtatcatagc taaacaaatc gagttgtgtg
      361 tccgtttttg ggcgttctgc tagcttgttt aaagtctctt gaatgaatgt atgttctaag
      421 tcaaaaaact ctgacagcgc ctttatatag ataaagtccg tataattgtg taaaagtaaa
      481 aaggccatat aacagtcctt ttacggtaca atgtttttaa cgacaaaaac atacccagga
      541 ggacttttac atgacccaag tacattttac actgaaaagc gaagagattc aaagcattat
      601 tgaatattct gtaaaggatg acgtttctaa aaatatttta acaacggtat ttaatcaact
      661 aatggaaaat caacgaacag aatatattca agcaaaagaa tatgaacgaa cagaaaaccg
      721 acaaagtcaa cgaaatggct attatgagcg cagctttacg acacgtgtag gcacgctaga
      781 attaaaagta cccagaacac gtgatggcca tttttcaccc acagtgtttg aacgttatca
      841 acgaaacgaa aaagcc
//
LOCUS       DAFEKH010000176          855 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.188, whole genome shotgun sequence.
ACCESSION   DAFEKH010000176
VERSION     DAFEKH010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..855
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.188"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            66..365
                     /locus_tag="LP386_003018"
     CDS             66..365
                     /locus_tag="LP386_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920163.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHLYNHSAIIRIENTMECDKRLAKSKENLAVVRLVDMEVINNEI"
     gene            355..519
                     /locus_tag="LP386_003019"
     CDS             355..519
                     /locus_tag="LP386_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920164.1"
                     /translation="MKFKIFEEDTRYELEEKLNEFAKNNEIQHISLATSKSGCTTYYA
                     AVVSYVSREV"
     gene            608..>855
                     /locus_tag="LP386_003020"
     CDS             608..>855
                     /locus_tag="LP386_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HBL1920165.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLI"
BASE COUNT          290 a          135 c          210 g          220 t
ORIGIN      
        1 agtgagacta ttcgtaagtt tgggatttcg atattaaatg atgatcgtaa atgggaggca
       61 gaaagatgaa actaaaagac ggattctacg ctagtagtca tggtatcggc ggtttaatgc
      121 tagatatgcc gacaaagaat cctaaaacac gtaagaaacc aaaattcaaa gtcggtgaca
      181 tggttcgctg cgaagcagaa gggttcatct atccatttcg tggatatgta gagcatctct
      241 ataatcactc agcgatcatt cgcattgaaa acacgatgga atgtgacaag cggttagcga
      301 aaagcaaaga gaatttagca gtggtgagat tggtggatat ggaggttata aacaatgaaa
      361 tttaaaatct ttgaagagga cacacgctat gaattagaag aaaaattaaa tgaatttgca
      421 aagaataatg aaattcagca tatatcttta gcaacttcta agtccggttg tacaacttac
      481 tatgcagctg ttgtgagcta tgtaagtcga gaagtgtaac tcggcaaata aaaaagccgg
      541 atcgctccga ctgattcaat aaattccaca agtttattat atcacataaa aggggcggtt
      601 tgacttgatg caattgttac gagaggtaga tttcaaacag acaagatgta atgcgagaga
      661 tgtgctgaag aactttcggc gtttggagcg gatggcaggt cgctctttga tagatattaa
      721 gtcgccgatt attacggaca tgccgaaggc accgaagcac ggcaataagg cagaagacgc
      781 gatcattcag atgatggata tagaagctga aagagacgcg attctagcgg ctttgatggc
      841 tctcagtctg attag
//
LOCUS       DAFEKH010000177          855 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.189, whole genome shotgun sequence.
ACCESSION   DAFEKH010000177
VERSION     DAFEKH010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..855
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.189"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            66..365
                     /locus_tag="LP386_003021"
     CDS             66..365
                     /locus_tag="LP386_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920166.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKPKVKVGDMVRCEA
                     EEFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVARLVDMEVINNEV"
     gene            355..519
                     /locus_tag="LP386_003022"
     CDS             355..519
                     /locus_tag="LP386_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920167.1"
                     /translation="MKFKIFEEDTRYKLEKELNDFAKNNEIQHISLATSKRGYANYYA
                     AVVSYVSREV"
     gene            608..>855
                     /locus_tag="LP386_003023"
     CDS             608..>855
                     /locus_tag="LP386_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HBL1920168.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILVALMALSLI"
BASE COUNT          293 a          129 c          210 g          223 t
ORIGIN      
        1 agtgatgcta ttcgtaagtt tgggatttcg atattaaatg atgatcgtaa atgggaggaa
       61 atgagatgaa actaaaagac ggattttacg ctagtagtca cggcatcggc ggtttaatgc
      121 tagatatgcc gacaaagaac cctaaaacac gtaagaaacc aaaagtcaaa gtcggtgaca
      181 tggttcgctg tgaagcagaa gagttcattt atccgtttcg tggatatgta gaacacgtct
      241 ataatcactc agcgatcatt cgtattgaaa acacaatgga atgcgataag tggttagcga
      301 aaagcaaaga gaatttagct gtagcgagat tggtggatat ggaggttata aacaatgaag
      361 tttaaaatct ttgaagagga cactcgttat aaattagaaa aagaattaaa cgattttgcg
      421 aaaaacaatg agattcagca tatatcttta gcaacttcta agagaggtta tgcaaattac
      481 tatgcagctg ttgtgagcta tgtaagtcga gaagtgtaac tcggcaaata aaaaaagccg
      541 gatcgctccg actgattcaa taaatccaac acatttatta tatcacataa aggagcggtt
      601 tgacttgatg caattgttac gagaggtaga tttcaaacag acaagatgta atgcgagaga
      661 tgtgctgaag aactttcggc gtttggagcg gatggcaggt cgctctttga tagatattaa
      721 gtcgccgatt attacggata tgccgaaggc accgaagcac ggcaataagg cagaagacgc
      781 gatcattcaa atgatggata tagaagcgga gagagacgcg attctagtgg ctttgatggc
      841 tcttagtctg attag
//
LOCUS       DAFEKH010000178          854 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.190, whole genome shotgun sequence.
ACCESSION   DAFEKH010000178
VERSION     DAFEKH010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..854
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.190"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(99..299)
                     /locus_tag="LP386_003024"
     CDS             complement(99..299)
                     /locus_tag="LP386_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL1920169.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
     gene            695..844
                     /locus_tag="LP386_003025"
     CDS             695..844
                     /locus_tag="LP386_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920170.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
BASE COUNT          281 a          146 c          131 g          296 t
ORIGIN      
        1 tttatacact actattcagc ccattcaacg accaatgaat tttttcgtac aaaaaaaccg
       61 tcttttcttt cgaaaagacg gttaaaagtc aatttttatt aagctttaac aatgtttgtt
      121 gcttgagggc cacgttgacc atcttcaaca tcgtaagaca ctgcttggcc ttcttctaaa
      181 gttttgaagc cgtcaccttg gatagctgaa aaatgtgcaa atacatcatt tccatcttca
      241 ccagtgataa agccaaaacc tttgtctgcg ttgaaccatt ttactgtacc gttattcata
      301 aataaattcc tcctgatacg tatcaatgta cgttttttcg ttgcaataaa tatttgatag
      361 gcaaaaggag ttttatctat gtagatatat cgctcaaatt acgtttcaaa atagattact
      421 catttaatat atcatgcttt ttctaataac acaaggataa tgcaatgaaa tataaaattc
      481 attgtcttct attgtcttcg aatcgaagaa aaagttgaat aaccgcgatt gattcacttt
      541 ttgttttctt gtttatttgc ttttatctgc aacttttgac tttaaaattt cttaactatg
      601 aaaacctttc aattggtggt atacttataa atggaatttc gttatcaacg cgttcgttgc
      661 ctttcagcaa gtatttaaag aaaggagaat ggctatgaca ttctataaca aagatataca
      721 atatcgagta accttggata cagatttgaa tctatttgtc gtttttgaca aagaaaatac
      781 caatcatgta gcgacaggtg ttacgatcga acaagcagtg caagaattaa aaaaatctgc
      841 ataaggagtg gaaa
//
LOCUS       DAFEKH010000179          823 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.191, whole genome shotgun sequence.
ACCESSION   DAFEKH010000179
VERSION     DAFEKH010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..823
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.191"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            22..>823
                     /locus_tag="LP386_003026"
     CDS             22..>823
                     /locus_tag="LP386_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL1920171.1"
                     /translation="MPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSESLAIDILT
                     FLTGISSRDGEKFPVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIADHIESFTD
                     YDFAHLLFSDGSITQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVIS
                     TFALDFIHSNREIFKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDD
                     LLDERLKNNIGLKFAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLEN"
BASE COUNT          253 a          142 c          186 g          242 t
ORIGIN      
        1 cgaggagggt ggaaagaaac cttgccagaa attgcggatg aaatcagtat cctcaacttg
       61 acgagtaagt cagaaaatca aggtctgctt gatccttatg tgattatgaa gaaaaagaaa
      121 gactcggaaa gtttagcaat tgatattctg acttttttaa caggaatttc aagtcgagac
      181 ggggagaagt ttcctgtgtt acgtaaagcc attcgaacgg tgactcaaag tgatcaacgg
      241 gggttattac aagttattaa cgaattgcga aaagacgggt caccaatcgc ggaaaatatc
      301 gccgatcata tcgagtcctt taccgattat gattttgctc atttgctttt ctcagacggc
      361 tcgattaccc aatcgattag tttagataaa cagctaaata tcattcaagt ggcggatttg
      421 gttttaccgg atgcagaaac gacttttgaa gaatatacca ccatggaatt gcttagtgtt
      481 tcgatgctaa tcgtcatttc cacttttgcc ttggacttta tccatagtaa ccgagaaatc
      541 ttcaaaattg tcgatttgga tgaggcttgg agttttcttc aagtggctca aggaaaaacg
      601 ttatcgaata agcttgttcg tgctggtcgg gccatgaatg ctggggtcta tttcgtcact
      661 caaaatagcg acgatttatt agatgaacgt ttaaaaaata atatcgggtt gaagtttgct
      721 tttcgcagta ccgatattca tgaaatcaag aaaaccttgg aattctttgg tttggatcag
      781 gaggatcaaa gcaatcaaaa acgcctgcga gatttggaaa acg
//
LOCUS       DAFEKH010000180          791 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.192, whole genome shotgun sequence.
ACCESSION   DAFEKH010000180
VERSION     DAFEKH010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.192"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..672
                     /locus_tag="LP386_003027"
     CDS             <1..672
                     /locus_tag="LP386_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1920172.1"
                     /translation="SGKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDN
                     NKFTSKMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTD
                     FLNKLSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRK
                     IIKVDKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLH
                     SMGLA"
BASE COUNT          292 a          123 c          147 g          229 t
ORIGIN      
        1 agcggtaaat actatatttc tttgttgtgt aaagaagaaa ttatcgaatt acctaaaact
       61 aattccacaa ttggtattga cttaggtatt atggactttg cgattctttc tgatggacaa
      121 aaaattgata ataataaatt cacgtccaaa atggaaaaga aactaaagcg tgaacaacgc
      181 aaattgtcta ggcgtgcttt attggctaaa aataaaggta ccaatctatt tgaagctaaa
      241 aattatcaaa aacaaaaacg caaagtagct agattgcatg aaaaagtaat gaatcaacgt
      301 actgattttc tgaataagtt gagtacagaa atgatcaaaa atcacgatat tatctgtatt
      361 gaagacttaa acacaaaagg tatgttgcga aatcataaat tagctaaaag tatttctgat
      421 gtttcttggt caaagtttgt gactaaatta caatacaagg ctgactggta tggacgaaaa
      481 atcatcaaag tagataaatg gtttccgtct agtcagattt gttcagagtg cggacataaa
      541 gatggcaaga aatctcttga aattcgagaa tggacttgtc ctgtttgtca tactcatcat
      601 gatcgtgata tcaatgctag tatcaatatt ctgaccgaag gtctaagact acattctatg
      661 ggattggctt agatccaatc atcaagaacc gtaggaacta cggggatagc ttggtaaata
      721 agagacaccg ctgttagtaa agaaatacgc tatcaagtat gctctattcc caagaagctc
      781 ccacttcaag c
//
LOCUS       DAFEKH010000181          763 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.193, whole genome shotgun sequence.
ACCESSION   DAFEKH010000181
VERSION     DAFEKH010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..763
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.193"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(237..716)
                     /locus_tag="LP386_003028"
     CDS             complement(237..716)
                     /locus_tag="LP386_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920173.1"
                     /translation="MCYFDREQDFFYYGGMGGGSIVPKINLVELDVNNYRELYVFNSL
                     DFEIPMKQMKNIDIHILPSESCQIEYSIEYFYKGKKIKKCDKCFESAVVKFPQFKLNP
                     AASIQFQGHVFDVLAKDNIKKYKKGNIFHIDIQISSNLEDIKKAFKIKTIGTAPNFK"
BASE COUNT          261 a          101 c           85 g          316 t
ORIGIN      
        1 aacaataaat gaagactttt ttattgttaa ttgtttattt ttctattatt agatatgaaa
       61 atcgcattta gataaaatag aaaaatatga atatatttta aatattaaga tgagagtcat
      121 taacttatga tagtagtcaa tttgcttttc actaattaca aaatatgtga tataggaagt
      181 ttagttattg ttctcataat gccatcctgt ttttagatta tctagtaatt tttttgttat
      241 ttaaaattag gagcagtgcc aattgtttta attttaaagg ctttttttat atcttctaaa
      301 ttagaagata tttgtatatc aatatggaat atattacctt ttttgtattt ttttatgtta
      361 tctttagcta aaacatcaaa tacatgtcct tgaaattgta tcgaggcagc tggatttagt
      421 ttaaattgag gaaactttac cacagctgat tcaaaacact tgtcacattt ttttattttt
      481 ttacctttgt aaaaatattc gattgaatat tctatttggc acgactcact tggcagtata
      541 tgtatgtcaa tatttttcat ctgtttcata ggtatttcaa aatctaaact attaaaaaca
      601 tataattccc tgtaattatt tacatctaac tctactaaat ttatctttgg aacaatagat
      661 cctccaccca ttccaccata ataaaaaaaa tcttgttctc tatcaaaata gcacatatta
      721 agctcagttt gtttatcatc ctcaataatt ttataaatca aac
//
LOCUS       DAFEKH010000182          666 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.195, whole genome shotgun sequence.
ACCESSION   DAFEKH010000182
VERSION     DAFEKH010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..666
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.195"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            55..666
                     /locus_tag="LP386_003029"
                     /pseudo
     CDS             55..666
                     /locus_tag="LP386_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
BASE COUNT          274 a          112 c          125 g          155 t
ORIGIN      
        1 gacagaaaaa ttaaggtgtg tagactagaa gaaaacatac caggaggaat ttttatgtct
       61 aagagaacac gaagaacttt ttcacaagaa ttcaagcaac aaatcgtcaa tctttactta
      121 gctggaaagc cacgtgtaga aatcattcga gaatatgaac taacggcttc agcatttgac
      181 aaatgggtaa agcaatctaa aacgagtggt tcattcaaag aaaaagataa tcttacgcct
      241 gaacaaaaag aattgttaga actacgtaaa agaaaccagc aattagaaat ggaaaatgat
      301 attttaaagc aagcagcgct gatattcgga cgaagagaca agtaatcgat gcgaataagc
      361 atctttaccc tatatcagcg atgtgcagaa tattaggtct atcacgtcag tcctattatt
      421 atcaatcaaa accaaagaaa gacgaatcag aacttgaaga agtagtcgct gaagaattta
      481 tccgcagccg aaaggcctac ggctcaagaa aaataaaaaa agccttatca aaacgaggca
      541 ttcagatcag ccgacgaaaa attagtagaa tcatgaaaaa tagaggatta aaatcgagct
      601 atactgttgc ttattttaaa gtacatcatt ctacttgcaa tgaagccaaa acgacaaacg
      661 tattga
//
LOCUS       DAFEKH010000183          630 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.196, whole genome shotgun sequence.
ACCESSION   DAFEKH010000183
VERSION     DAFEKH010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..630
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.196"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..>630
                     /locus_tag="LP386_003030"
     rRNA            <1..>630
                     /locus_tag="LP386_003030"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          156 a          144 c          196 g          134 t
ORIGIN      
        1 gaaagccccc ggctcaaccg gggagggtca ttggaaactg ggagacttga gtgcagaaga
       61 ggagagtgga attccatgtg tagcggtgaa atgcgtagat atatggagga acaccagtgg
      121 cgaaggcggc tctctggtct gtaactgacg ctgaggctcg aaagcgtggg gagcaaacag
      181 gattagatac cctggtagtc cacgccgtaa acgatgagtg ctaagtgttg gagggtttcc
      241 gcccttcagt gctgcagcta acgcattaag cactccgcct ggggagtacg accgcaaggt
      301 tgaaactcaa aggaattgac gggggcccgc acaagcggtg gagcatgtgg tttaattcga
      361 agcaacgcga agaaccttac caggtcttga catcctttga ccactctaga gatagagctt
      421 ccccttcggg ggcaaagtga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg
      481 ttgggttaag tcccgcaacg agcgcaaccc ttattgttag ttgccatcat tcagttgggc
      541 actctagcaa gactgccggt gacaaaccgg aggaaggtgg ggatgacgtc aaatcatcat
      601 gccccttatg acctgggcta cacacgtgct
//
LOCUS       DAFEKH010000184          592 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.198, whole genome shotgun sequence.
ACCESSION   DAFEKH010000184
VERSION     DAFEKH010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..592
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.198"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..579
                     /locus_tag="LP386_003031"
     CDS             <1..579
                     /locus_tag="LP386_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBL1920174.1"
                     /translation="GIKSHLWVTQNIWGDHTDPCGYLSEMGVSKEKLAYDLAHGFTDD
                     NPTTSDDNPTTSEDKPVIDPTRAGAANSTLTDGTNYAHVDQFGEIENANLHVAGWHIA
                     NYKYEYIFIMDYNTGKELARVRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVY
                     VMMRATNDPEGNTKGGAQDFHDKRWYLNIPQR"
BASE COUNT          203 a          105 c          122 g          162 t
ORIGIN      
        1 ggaatcaaat cgcatttatg ggtaacacaa aatatttggg gcgatcatac agatccttgc
       61 ggttatcttt ctgaaatggg tgtaagtaaa gaaaaactag cctatgattt ggctcatggt
      121 tttacggatg ataatccaac tacttcggat gataatccaa ctacttcgga ggataaacca
      181 gtaattgatc caactcgagc aggtgctgca aattctacgc tgacagatgg aacaaattac
      241 gcccacgttg atcagttcgg agaaatcgaa aacgcaaact tgcatgtagc tggatggcac
      301 attgctaatt ataaatacga gtatattttc attatggact acaatactgg aaaagaacta
      361 gctagagtaa gagctgatgg gatttataga ccagacgtaa atcaagctta taatacttta
      421 ggaaatgttg gctatcatgt atctttcaat atgcgtgatt tccctaataa gaaagtatac
      481 gtcatgatgc gtgcgacaaa cgatccagaa ggaaatacta agggtggagc acaagatttt
      541 catgacaagc gttggtattt aaatattcca caacgataaa aaattccccc ct
//
LOCUS       DAFEKH010000185          585 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.200, whole genome shotgun sequence.
ACCESSION   DAFEKH010000185
VERSION     DAFEKH010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..585
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.200"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            271..438
                     /locus_tag="LP386_003032"
     CDS             271..438
                     /locus_tag="LP386_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920175.1"
                     /translation="MKLSVEGTPEEIQELLQAIGSSKEQKVSVSNSDIDGICNCLNRE
                     KISNPFILKGE"
     gene            443..>585
                     /locus_tag="LP386_003033"
     CDS             443..>585
                     /locus_tag="LP386_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920176.1"
                     /translation="MNENQLRELFKTNEANKTMEATFYETQKSLALIAKQSKYFYDQL
                     ILQG"
BASE COUNT          218 a           92 c          110 g          165 t
ORIGIN      
        1 catttaccag tgttattatg gtagtgtcga aagattagga aacaggatcg acaaaataaa
       61 cgaagggagg caatctccct catcgtttta aacttcttct tagatagaca gcaactaatt
      121 atgaagaaaa ggatgtgaat tcaactcctc ctaaattctt catcggttgc tgtttatttt
      181 gattagacag cagcactcac aaaactaaac atgttcttgt cgtctttcaa ctgctgctgt
      241 ctattaattt atgtattgga gggaagaaaa atgaaattat cagtagaagg cactccagaa
      301 gaaatacaag aattgctcca agctattggt agtagcaagg agcaaaaggt aagtgtttct
      361 aattcagata ttgacggtat ttgcaattgt ttaaacagag aaaaaatatc taatcctttt
      421 attttgaaag gggagtaaac aaatgaacga aaatcaatta agagagttgt ttaaaacgaa
      481 tgaagcaaac aaaacaatgg aggcgacatt ctacgaaact caaaaaagct tagcgttaat
      541 cgcaaaacaa tcaaagtatt tctacgatca gcttattctg caagg
//
LOCUS       DAFEKH010000186          562 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.201, whole genome shotgun sequence.
ACCESSION   DAFEKH010000186
VERSION     DAFEKH010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 562)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 562)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..562
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.201"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..144
                     /locus_tag="LP386_003034"
     CDS             <1..144
                     /locus_tag="LP386_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HBL1920177.1"
                     /translation="FCVPDSFSNYRISREVGYSERSIQRMKSEALIEFAEAYKHGRII
                     AYK"
     gene            157..543
                     /locus_tag="LP386_003035"
     CDS             157..543
                     /locus_tag="LP386_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920178.1"
                     /translation="MWKDYVSLKELKKDLVFKRIVEWSESELILEDGTKMEVVCSESD
                     CCAWAEGEFKNVKLDAVITDIKIFDKGNRLYNGDGHTSYAEVVVYHNRNEIAKAECTA
                     NDGNGGYYYSVCALKVKDKLCIVTDA"
BASE COUNT          195 a           70 c          139 g          158 t
ORIGIN      
        1 ttctgtgtgc cagatagctt ctcaaactac aggattagcc gtgaagtggg ttattcagaa
       61 agaagcatac aaaggatgaa gtcggaagct ctaatagagt ttgcagaagc gtataaacac
      121 ggaagaataa ttgcttataa atagggggac catataatgt ggaaagatta tgtatcgttg
      181 aaagagttga aaaaagatct tgttttcaaa agaattgtag aatggtcaga gagtgaatta
      241 attttagaag atggaaccaa aatggaagtt gtatgtagcg aatcagattg ctgcgcatgg
      301 gccgaaggtg aattcaaaaa tgtaaagctt gatgcagtga ttacagatat aaagattttt
      361 gataaaggta accgtctcta taatggtgac ggacatacct cttatgctga agtcgttgtt
      421 tatcataatc gtaatgagat cgctaaagca gaatgcacag cgaatgatgg gaatggcggc
      481 tactattata gtgtttgtgc tttaaaggtc aaagacaaac tttgtatagt gactgacgca
      541 taaaaaaatg gcggtttttt gg
//
LOCUS       DAFEKH010000187          525 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.202, whole genome shotgun sequence.
ACCESSION   DAFEKH010000187
VERSION     DAFEKH010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..525
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.202"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..134
                     /locus_tag="LP386_003036"
     CDS             <1..134
                     /locus_tag="LP386_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL1920179.1"
                     /translation="VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
BASE COUNT          220 a           75 c           56 g          174 t
ORIGIN      
        1 aagtgaatca gacatttatt tccagtgtca gcaatcaacg taatcatatt ccaagaaaat
       61 cattgaatta cagaacacca atcgaaatat ttttgagcta tgtacaagaa gcattttatt
      121 ctagcttaat ttgacaaatc atacaaacaa aaataaataa agtcggattt ttctgataat
      181 tcaacgcaaa aaaacgaaca atttttcaat aaatcagtct tctaaaatag ataacctaaa
      241 aaaaacgaac aaacaaataa aatgactgtc cttcattcac taaacatatt tttatttttt
      301 atattgttaa aaattcacaa ttatttttta atagaattat ctgttttcca aattttataa
      361 cataaaaaac cttttttaac ggcatttata tgctttttca gaaattaact gatgatttca
      421 aaaagaaaac atgtcataat atttcccata ttgtgcaaaa aaatacaagg tggaggctct
      481 actatgattg aagaatatat tgagaaaaat attttaagac agctg
//
LOCUS       DAFEKH010000188          524 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.203, whole genome shotgun sequence.
ACCESSION   DAFEKH010000188
VERSION     DAFEKH010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..524
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.203"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(6..359)
                     /gene="tnpB"
                     /locus_tag="LP386_003037"
     CDS             complement(6..359)
                     /gene="tnpB"
                     /locus_tag="LP386_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HBL1920180.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(349..>524)
                     /locus_tag="LP386_003038"
     CDS             complement(349..>524)
                     /locus_tag="LP386_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920181.1"
                     /translation="VPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIYNGINNYI
                     LQAILKELLSNAL"
BASE COUNT          153 a          115 c           90 g          166 t
ORIGIN      
        1 ccagcttaaa aaactccttt ttttcctggc aaaatagctc gaggttgatc gatacttaat
       61 ccttctaaca accatcgaac ctgttggttc gttaaggttc gaacttcgtc tttcgtccga
      121 ggccatttta acttgccgtt ttctatccgc ttataacaga gaagaaaacc atcaccgtcc
      181 caatagagaa gtttgaaacg gtcttgacgg ttcccgcaaa ataaaaaaac ggcatcttcg
      241 taaagctcga gttgatactc ttgttgaata agactggcaa gaccatcaat tccttttcgc
      301 aaatctgttt ttccgcacac aatataaata tgtttggttt gaagtaaatc ataaagcatt
      361 ggacaacagt tctttcaaaa tagcttgaag aatataattg ttaataccgt tatagatcaa
      421 aacttcagaa ccattctctc ttttgatgcg catcgctaac ttggcagccg cgggtttacc
      481 tttttctggt gcactctttt cgtttcctaa ttggacagga acaa
//
LOCUS       DAFEKH010000189          515 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.204, whole genome shotgun sequence.
ACCESSION   DAFEKH010000189
VERSION     DAFEKH010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 515)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 515)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..515
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.204"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
BASE COUNT          176 a           67 c          105 g          167 t
ORIGIN      
        1 ggtatgtggt taaaaaagaa aaatagctag gagatttttg agagatgact ggtaaattta
       61 aaaatgatag aaatggagag tatgtatgag taataaacaa tttttatggt cttcttttgc
      121 atttattgtt gttgatattt ttttccgata ttttaataac gatatgatat ttaactggca
      181 aagaattata atcgattact gtattttttg tataatatat tttttagtga aaacatttct
      241 aaaatacgca aaaaaataaa attgaagatg ttattaaatc gcgattattt acggagattt
      301 atataaataa aaaccccctg acgaagtcga agggggtttt tattttggtt tgaggtttgc
      361 atacctaccg aaaaggtagg gcagcaaatc gtcaaacagg tatcagctaa ttgcaccata
      421 agggtgcgct gatactcggc tcaaaagagc cgaaagagcc gtctgcaaga cccctcggcg
      481 agcccacact ttgcttgcaa agtatagtgg gttat
//
LOCUS       DAFEKH010000190          511 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.denovo.205, whole genome shotgun sequence.
ACCESSION   DAFEKH010000190
VERSION     DAFEKH010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..511
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.denovo.205"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(<1..132)
                     /locus_tag="LP386_003039"
     CDS             complement(<1..132)
                     /locus_tag="LP386_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBL1920182.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          184 a           93 c           92 g          142 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactattag a
//
LOCUS       DAFEKH010000191        59179 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.guided.011, whole genome shotgun sequence.
ACCESSION   DAFEKH010000191
VERSION     DAFEKH010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59179)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59179
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.guided.011"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(565..792)
                     /locus_tag="LP386_003040"
     CDS             complement(565..792)
                     /locus_tag="LP386_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1920183.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            complement(801..1274)
                     /locus_tag="LP386_003041"
     CDS             complement(801..1274)
                     /locus_tag="LP386_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBL1920184.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            complement(1914..2087)
                     /locus_tag="LP386_003042"
     CDS             complement(1914..2087)
                     /locus_tag="LP386_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920185.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            2504..3070
                     /gene="amaP"
                     /locus_tag="LP386_003043"
     CDS             2504..3070
                     /gene="amaP"
                     /locus_tag="LP386_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBL1920186.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            3083..3271
                     /locus_tag="LP386_003044"
     CDS             3083..3271
                     /locus_tag="LP386_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBL1920187.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            3284..3841
                     /locus_tag="LP386_003045"
     CDS             3284..3841
                     /locus_tag="LP386_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBL1920188.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            3873..4115
                     /locus_tag="LP386_003046"
     CDS             3873..4115
                     /locus_tag="LP386_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBL1920189.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            4456..5670
                     /locus_tag="LP386_003047"
     CDS             4456..5670
                     /locus_tag="LP386_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HBL1920190.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            5701..5919
                     /locus_tag="LP386_003048"
                     /pseudo
     CDS             5701..5919
                     /locus_tag="LP386_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173391.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            6338..6811
                     /gene="dfrF"
                     /locus_tag="LP386_003049"
     CDS             6338..6811
                     /gene="dfrF"
                     /locus_tag="LP386_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HBL1920191.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            6938..7594
                     /locus_tag="LP386_003050"
     CDS             6938..7594
                     /locus_tag="LP386_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HBL1920192.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            7776..8306
                     /locus_tag="LP386_003051"
     CDS             7776..8306
                     /locus_tag="LP386_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBL1920193.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
     gene            8852..9094
                     /locus_tag="LP386_003052"
     CDS             8852..9094
                     /locus_tag="LP386_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HBL1920194.1"
                     /translation="MENELLENLGRLHTTELGVIRIKKNLSLNVENVIEWCKEKISLS
                     NAEITRKGKNWYITIDNCIITVNAYSYTVITAHKVK"
     gene            9091..9561
                     /locus_tag="LP386_003053"
     CDS             9091..9561
                     /locus_tag="LP386_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBL1920195.1"
                     /translation="MINFSIKELNAFAVIGQEVELTNYQKKNIQISTQFWRKFNSSLK
                     KAYLSQSGNWVKYAFMERRNGKLYYFCSIPQRTITPEGFLYKEIPSYKYLVVEHIGAM
                     DKIYETYGKIYEEIIPSTSYIPIKDIILHFEKYDYRFHWNSDNSVIEIWIPIQD"
     gene            9689..10903
                     /locus_tag="LP386_003054"
     CDS             9689..10903
                     /locus_tag="LP386_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBL1920196.1"
                     /translation="MNDKNFIEELRQKREEYGVTQTRLAVACGISREYYNRIEKGKQP
                     LNDELREIIEKQIERFNPQEPLFLLIDYFRVRFPTTDALAIIRDVLQLKSNYMLYEDY
                     GKYGYESKYVLGDINIMCSMQEHLGVLLELKGKGCRQMECYLLAQERSWYDFMLDCMT
                     AGGVMKRLDLAINDKAGILDIPKLKEKYKAGECMSYFRMQKDYSGTEKCGSDLPKNTG
                     ETLYLGSTSSELYMCAYQKNYEQYVKNGTEIEDTEIKNRFEIRMKNERAYYAVVDLLT
                     YRDAERTAFSIINHYVRFVDREDDKPKSQWITNDDWAWFVGENREPIRLTTKPEPYTL
                     QKALHWLQRQVAPTIKMVQALDRENRTTILKDMIEQAELKDKHKHLLQLEKSTIEERI
                     DTAVPQENDGIF"
     gene            11892..12101
                     /locus_tag="LP386_003055"
     CDS             11892..12101
                     /locus_tag="LP386_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA wybutosine-synthesizing protein 3-like
                     protein"
                     /protein_id="HBL1920197.1"
                     /translation="MNCLERFYRKGVCVIDNAVKTIQKKNGKCGIGNRGKTKIVVKEH
                     FSEKGKTMEELLTDVMLEKAKQTIA"
     gene            12213..13826
                     /locus_tag="LP386_003056"
     CDS             12213..13826
                     /locus_tag="LP386_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1920198.1"
                     /translation="MKQQIYNTALYLRLSRDDELQGESSSITTQRSMLRLYAKEHHLN
                     VIDEYIDDGWSGTNFDRPSFQRMIEDIEAGKINCVVTKDLSRLGRNYIMTGQYTELYF
                     PSHNVRYIAIDDGVDSEKGESEIAPFKNIINEWVARDTSRKVKSAFKTKFAEGAHYGA
                     YAPLGYKKHPDIKGKLLVDDETKWIIEKIFSLAYQGYGSAKITKQLRAEKVPTASWLN
                     FTRYGTFAHIFEGKPESKRYEWTIAHVKAILKSEVYIGNSVHNMQSTVSFKSKKKVRK
                     PESEWFRVENTHEPIIDKEVFYRVQEQIKSRRRQTKEKATPIFAGLVKCADCGWSMRF
                     GTNKTNKTPYSYYACSYYGQFGKGNCSMHYIRYDVLYQAVLERLQYWAKAVQQDEEKV
                     LNKIQKAGNAERIREKKKKASTLKKAENRQNEIDRLFAKMYEDRACEKITERNFVMLS
                     SKYQKEQIELEQQITSLREELSKMEQDMIGAEKWIELIKEYSVPKELTAPLLNAMIEK
                     ILIHEATTNEDNERIQEIEIYYRFIGRVE"
     gene            13861..15072
                     /locus_tag="LP386_003057"
                     /pseudo
     CDS             13861..15072
                     /locus_tag="LP386_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
     gene            15095..16021
                     /gene="glsA"
                     /locus_tag="LP386_003058"
     CDS             15095..16021
                     /gene="glsA"
                     /locus_tag="LP386_003058"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HBL1920199.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            16229..17689
                     /locus_tag="LP386_003059"
     CDS             16229..17689
                     /locus_tag="LP386_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920200.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIREIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            17910..19673
                     /locus_tag="LP386_003060"
     CDS             17910..19673
                     /locus_tag="LP386_003060"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HBL1920201.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            19757..20215
                     /locus_tag="LP386_003061"
     CDS             19757..20215
                     /locus_tag="LP386_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HBL1920202.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            20324..21007
                     /locus_tag="LP386_003062"
     CDS             20324..21007
                     /locus_tag="LP386_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBL1920203.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            21154..21768
                     /locus_tag="LP386_003063"
     CDS             21154..21768
                     /locus_tag="LP386_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HBL1920204.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            21784..21990
                     /locus_tag="LP386_003064"
     CDS             21784..21990
                     /locus_tag="LP386_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920205.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            22531..23661
                     /locus_tag="LP386_003065"
     CDS             22531..23661
                     /locus_tag="LP386_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBL1920206.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     gene            23753..24508
                     /locus_tag="LP386_003066"
     CDS             23753..24508
                     /locus_tag="LP386_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBL1920207.1"
                     /translation="MKVSQKIILSILLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEP
                     KSIPTTLNVALIGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGM
                     NKINAAYSYGGVDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSL
                     DLDGVYINKGEQVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFK
                     LPKAVGKLLGSIQTNLPESVLLDCGMDFLKDIC"
     gene            24566..26605
                     /locus_tag="LP386_003067"
     CDS             24566..26605
                     /locus_tag="LP386_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HBL1920208.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSYQATRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(26714..27865)
                     /locus_tag="LP386_003068"
     CDS             complement(26714..27865)
                     /locus_tag="LP386_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBL1920209.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(28019..28549)
                     /locus_tag="LP386_003069"
     CDS             complement(28019..28549)
                     /locus_tag="LP386_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBL1920210.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(28648..28998)
                     /locus_tag="LP386_003070"
     CDS             complement(28648..28998)
                     /locus_tag="LP386_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HBL1920211.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(29155..30684)
                     /gene="ahpF"
                     /locus_tag="LP386_003071"
     CDS             complement(29155..30684)
                     /gene="ahpF"
                     /locus_tag="LP386_003071"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HBL1920212.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(30694..31257)
                     /gene="ahpC"
                     /locus_tag="LP386_003072"
     CDS             complement(30694..31257)
                     /gene="ahpC"
                     /locus_tag="LP386_003072"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HBL1920213.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(31401..32063)
                     /locus_tag="LP386_003073"
     CDS             complement(31401..32063)
                     /locus_tag="LP386_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL1920214.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            32247..33893
                     /locus_tag="LP386_003074"
     CDS             32247..33893
                     /locus_tag="LP386_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBL1920215.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            33884..34966
                     /gene="uxuA"
                     /locus_tag="LP386_003075"
     CDS             33884..34966
                     /gene="uxuA"
                     /locus_tag="LP386_003075"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBL1920216.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(35074..36627)
                     /locus_tag="LP386_003076"
                     /pseudo
     CDS             complement(35074..36627)
                     /locus_tag="LP386_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            36775..37916
                     /locus_tag="LP386_003077"
                     /pseudo
     CDS             36775..37916
                     /locus_tag="LP386_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(38042..39121)
                     /locus_tag="LP386_003078"
     CDS             complement(38042..39121)
                     /locus_tag="LP386_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL1920217.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(39224..39664)
                     /locus_tag="LP386_003079"
     CDS             complement(39224..39664)
                     /locus_tag="LP386_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL1920218.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(39721..40131)
                     /locus_tag="LP386_003080"
     CDS             complement(39721..40131)
                     /locus_tag="LP386_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBL1920219.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(40311..40745)
                     /locus_tag="LP386_003081"
     CDS             complement(40311..40745)
                     /locus_tag="LP386_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL1920220.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(40845..41693)
                     /locus_tag="LP386_003082"
     CDS             complement(40845..41693)
                     /locus_tag="LP386_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL1920221.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            42082..43848
                     /locus_tag="LP386_003083"
     CDS             42082..43848
                     /locus_tag="LP386_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HBL1920222.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            43950..45209
                     /locus_tag="LP386_003084"
     CDS             43950..45209
                     /locus_tag="LP386_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBL1920223.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            45356..46657
                     /locus_tag="LP386_003085"
     CDS             45356..46657
                     /locus_tag="LP386_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1920224.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            46660..47511
                     /locus_tag="LP386_003086"
     CDS             46660..47511
                     /locus_tag="LP386_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1920225.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            47524..48339
                     /locus_tag="LP386_003087"
     CDS             47524..48339
                     /locus_tag="LP386_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HBL1920226.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELKLSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            48490..49656
                     /locus_tag="LP386_003088"
     CDS             48490..49656
                     /locus_tag="LP386_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL1920227.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPTQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            49886..50533
                     /locus_tag="LP386_003089"
     CDS             49886..50533
                     /locus_tag="LP386_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBL1920228.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            50617..51561
                     /locus_tag="LP386_003090"
     CDS             50617..51561
                     /locus_tag="LP386_003090"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HBL1920229.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            51696..53147
                     /locus_tag="LP386_003091"
     CDS             51696..53147
                     /locus_tag="LP386_003091"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HBL1920230.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            53168..54004
                     /locus_tag="LP386_003092"
     CDS             53168..54004
                     /locus_tag="LP386_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBL1920231.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            54004..54663
                     /locus_tag="LP386_003093"
     CDS             54004..54663
                     /locus_tag="LP386_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBL1920232.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            54789..55478
                     /locus_tag="LP386_003094"
     CDS             54789..55478
                     /locus_tag="LP386_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920233.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            55484..56440
                     /locus_tag="LP386_003095"
     CDS             55484..56440
                     /locus_tag="LP386_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HBL1920234.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHRIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            56484..56996
                     /locus_tag="LP386_003096"
     CDS             56484..56996
                     /locus_tag="LP386_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1920235.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(57252..57800)
                     /locus_tag="LP386_003097"
     CDS             complement(57252..57800)
                     /locus_tag="LP386_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL1920236.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(57889..59070)
                     /locus_tag="LP386_003098"
     CDS             complement(57889..59070)
                     /locus_tag="LP386_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HBL1920237.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
BASE COUNT        20105 a        10119 c        11568 g        17387 t
ORIGIN      
        1 ctcgagttac gagtttggaa cagcttttgt ctacagtctg tcattattat caaaataatg
       61 ttaaaaataa aaaagaattg tccatcactg ttattcaaat cattttatca aaactacata
      121 gtaaatgtta aaaagcaaca tgacataata tatagaaggc tttacagtat atatgggagc
      181 ttactaaaaa agaatggagt aagagttaac acaatgggcc attagctgaa gttttaagca
      241 cttcaaggta tgaaacagaa tggcctgtaa tactacatga ttatttagac tgctcaaact
      301 gctatcagtc tggtggaatg aataaagtat tatactaaaa gcagatccaa ctacaacgta
      361 acaggaaacc agttgtatca ggaaaagtga tagtacatgg agaagaaaag gccccctttg
      421 tatgagtcag tacatatctt atttatagat aaaacggtat tcaatcgaaa taaaaaatct
      481 gaataataga cgtaaataac ttctaaaagt ctcacacatc tatcattcag attatttttt
      541 atttactgtt tgttctactt tattttattc ttctggtata gtattcgagt catttttata
      601 ggtcaacaaa tcacctggtt gacactccaa aacttggcag attttttcga gagtggaaaa
      661 acggatggct tttgcttttc cattttttag aatagagatg tttgccatcg taatgcccac
      721 tttctcactc aattcagtca cactcatttt tttttgagct aatactacat ctaaattaac
      781 gataattgcc atgtcgcacc tcacactgtc aaatcatgat ctgtcttaag taaaatcgca
      841 tgttcaagca gtttttccag cacgcttgtt aatgtgtata ctgcaaaagg aatgaatacg
      901 acagcgattc ctaccaacat caaacctgga gcatcgtcta aatccgctac tttcataaat
      961 ttaggaagta agccaaaaaa ggcgaaacca ataaacaaaa tggttcgttc gatttttttt
     1021 agtatgttta agctttgagt ggaaaaagct tggttatctt cgattttttt caatagtttc
     1081 aataagaaat aagcaataac gatccctagg agaagggcaa agtaaatgac agaaacaaat
     1141 aatgtggtct gccaatcaaa attgaatcct ttttcgcttg tagcgatctg agtataaaaa
     1201 agtacgccga acaaaataaa tacggcactt atacctaaaa cgacaaattt taatagcaat
     1261 gttttaaatt tcatttttat ccctctttta tctttgatag ctaaaatata gcagaataat
     1321 tattgtaaaa caactatttt ttatcgaaaa acaataaaaa tatatcgttt ataaaaaatg
     1381 atagagtatg aaggtgtgga gtgcatttaa cagctttttt tgattgtaag aaacatttaa
     1441 aaccagttat tttagattct atgtgtgtct cttctataat gctagtttag atgcctggga
     1501 ttatattgga caatacagtt ggaggatttt ttattatcta gcgaagagaa gtgtaagtta
     1561 acagaactgt atgagaaaaa agacaactac gtagtagcta accgattcat taattttttc
     1621 aagttcatgt ttatttacgt atcagaattt ttcttattca atggtttggt gtaatcacca
     1681 cttatttgtc ctttattgct tatacaatgt tatacaaaag gaaaatcaag cattgacgca
     1741 tggggtggta ctatctagct gaaatagctt aataagcgca agtagatgca ttggattagt
     1801 ttataaatca aaagtgttag aggtattaag aagaagtaga aaaataaaat ggattgccga
     1861 ataaaaagta ccataaatcc taaaacatgt gccaacagat agatggcaca tgtttatttt
     1921 tttcgataat tttgtaacaa aaatacgaag atgaaaaaga atagagattc ccataatgta
     1981 gtagtccaac tgaattcttt actgatacca aataccatat ttcctagatt tgatacaatc
     2041 aaatagccaa tcgttatgat caatgaatag tacaatcttt tcatcatagg acatacctcg
     2101 tttttattta taagaatagt ataaaccaaa gaagtgaata agaaaaatga taatataaaa
     2161 ataaagtaag aacgcattaa agtaactaaa gttatttatt gtatttttta attctccgaa
     2221 aaaatttaat aaataaatag aatcttgtaa taataactga gcataatctt tgcaattttt
     2281 aatcttgaat aatatccttt aagtatagcc agcaatcaaa agtaaataga gaataagtaa
     2341 gcaattgtta tttcagtatc agactggcaa taaaacgccg ttatgatcca gcaatgtttg
     2401 gtagcgcttt atttactgat gctatgctaa ctgttcgcta tctatactgt gattgtcggt
     2461 agagttattt acagggtaaa aataagttta taggaggtgg aaaatgaata aggggttaaa
     2521 aataatcggt gttatcatga gtttactgct actttcagta tttctagcga ttgcgttgat
     2581 caatgcgccg tatattatgc ctgaacaatt ggaacgattt cgcttcttta ctttaacgaa
     2641 ttactacatg caacaatata ttttctgggc agctgtagta tttgccgttc ttgctattat
     2701 catcttgcta gtcgttcttt tctatccaaa gtcaagagga actttcgtta tgaaacggga
     2761 agatggcaaa ctaacaatcg acaaaaaagc gatcgaaggg ttggtacgtt cccatttaca
     2821 cgaagaagag ttcattcatt cacctaaagt acggatacgt tcaacgaaaa atcgaatcca
     2881 tatccatgtc aacggagact tgaaacgaac ttcttcatta gtagggaaaa caggtgtatt
     2941 gatgcaagat atcgaagaag aagtaactaa agtactcgga acaaaagaaa cggtcaaagt
     3001 ggcagtcaca tacagcggtt atgaagaaca agaagataca agagactaca agcactctcg
     3061 agtggaatag gagggccaaa taatgaaaga actattttca gcatacaagc tccctattat
     3121 ctttgggggt cttggactac tgctagctgt tttatggtta acgattggat ttttcaagac
     3181 attgttgatc ataatcatga cagcaattgg cgcaggaatc ggtttttatt tgaaacagtc
     3241 aggaatagtt gatcaatttt ttaaatcata ggaggaaaca aagatggaaa acaaaaacat
     3301 gaatacaaca aatggatcag ttttggcaaa tgaaaaagga gaaaaccgca tgatgaatgg
     3361 tgaattgact tatgaagaca aagtcatcca aaaaatcatc ggttatgcat tgaaagatgt
     3421 agatggtcta ttgacattag atggcggatt tttctcaaat atggctgaaa aattagtcaa
     3481 cacagataac gtaacagcag gtatcaatac agaagtaggt aagaaacaag tagctgtgga
     3541 tctagatgtg atcgtagaat acggtaaaga catcgaagat atttacaacc aaatcaaaga
     3601 attgatcagt actgaagtaa acaatatgac acatttagat gttatcgaag tgaatgtgaa
     3661 tgttgcagac atcaaaacac aagaagaata ccaaaaagat caagaaacag tacaagacaa
     3721 agtaacagaa gcagcaaaat ccacaggaca atttgcttca cgccaaacag ataaagcaaa
     3781 atctgctgta ggcaaaggtg cacaaaaagt caaagaaaat aacgaaccac gtgtacaata
     3841 agaagtaaga agtcagttag gaggaattta aaatgggatt tatttgggca ttaatcgtcg
     3901 gcggtatcat tggagcaatt gcaggagcaa tcacgaataa aggatcatca atggggatca
     3961 tcgcaaacat cattgctggt ttagtaggtt cagcaattgg acaagcttta ctaggaactt
     4021 ggggaccaac aattgcagga atggctatca ttccatcatt gatcggtgca atcattttag
     4081 tattagtcgt ttcattcttt gcacgtaaat tataagcaaa ttgaagaaaa acttatgttg
     4141 aaatgaagaa caaatttgag aaccgtagcg acactcgctg cggttctttt ttatatattt
     4201 tatatgaagt attctttatt ccttatgaaa aaatatcttt aaaaataaaa aaagacgaaa
     4261 ataaacggtt ttctataaaa agaagaccgt ttattttttg tctttatttg tgtgaaaaac
     4321 gaaaaagagc acaacacatc aagcttttat taattgtctg tcttttataa atgcaagtat
     4381 taattcaaaa aaacagaaga aaaaaacaac tacaccttct tttatactcg taatcgtaga
     4441 aaggaggcga aaaaaatgaa tacattacct atcaatacag gagatacagc attcatgatt
     4501 ttatgtacag caatggtttg cctgatgact cctggtctag ctttttttta cggcggatta
     4561 gcacggaaga ataatatact aacgatcatg tctcaatctt ttctctccgt tgggataaca
     4621 acgattatgt gggtatttgg tggattcgga ttggcctttg gacgggatat cggcggtgtt
     4681 attggaaacc cggcagattt ctttttgatg agacatgtta caagcttccc caacatgttt
     4741 catggtgcaa cgattccatt tttaatgttc tttctttacc aactgatgtt tatcgtgatt
     4801 accgttcctt tgatgacagg agcttttgca gggagattga atttaaaagg ctatattata
     4861 cttgttattt tttggaatct gctgatttat ttccctgttt gccactggat atggggtggc
     4921 ggatttttgg atcagatggg atttagagat ttcgctggtg gagcagtcat ccacacgaca
     4981 gctggattcg gctctttagc atgtatcctc acacttggtc aaagaaagat tcctttagga
     5041 gaaagaagtc agcatagcag tcttatggca gctgctatcg gtacaggact gctttggttt
     5101 ggctggttcg gttttaattc cggtggtgca cttcgagcag atgaacaagc agtcaatgca
     5161 tttggttcaa cattcatcgc tcttgcattt gcgatgatta cttggctgat cattgcaaaa
     5221 gtaaaaggaa atggctttga ttttgtcgac gtactaacag gatccgttgc tggattggca
     5281 gccattacgc cttgtgccgg ttatgtagaa gcaaaaagtg ccatgctgat tgggatcatt
     5341 gcgggtatcg tctgtcatgc tgctgttgat tttcgtaaaa agaaacaatg ggatgatgca
     5401 cttgatgtgt ggggtgttca tggcatgggc ggattcacag gtacgattct gatagggatc
     5461 tttgcatcta acagccattt actaacgaat ccaagcagct ggtacttctt agggattcaa
     5521 gtgattggtg tcatcattac tgccgtgtat gcctatgtgc tgacaacagt gattttaaaa
     5581 tcggcgatgc actttacaac gatcactact acaaaagaag aacaagaaga aggattggac
     5641 tttttcttct ttggcaacaa actcaattga aacaaattca aatagaaaag aggaagattc
     5701 atgcaacaaa gcaaaacgaa aattcctgca aaaaaattaa cgttctttgg ctttttggct
     5761 atgaccatct caatggtcgt ttcattatat gaatatccca cattcgcgac ctcaggcttc
     5821 agcttagtat ttttcttgtt attaggcggt ttgctatggt ttatccctgt ggcattgtgc
     5881 gcagcagaga tggcaacggt gaaaggatgg gaaaaaggtg tttcccaaac aaaaagatat
     5941 taagaaacag cccatgttta cctgcttgca aacaaaagaa tattgctact agactaagag
     6001 atactacata agtgtgttgg tatctctttt ttgttgccgt gaaacagcag actatttcat
     6061 ttctgcttga ttaccttaaa acttattagt ctatggtttg tcaagggctt gttgcgtgag
     6121 aaatgctgaa tatcaccctt tacaaaacat aggctgataa gtaacttttc aaaagcagaa
     6181 aagaaatggc aatgcttata acaatatgat ataatgcaga tgaagacaaa aaaggaattt
     6241 gtcgagctgg ttagttcgag ataattttga gtttgttaag atgtggtgca cttgatggaa
     6301 tcacaggtac gacatcatat tatggaggat gaaatagatg ataggtttga ttgttgcgag
     6361 gtcaaagaat aatgttatag gcaagaatgg taatatacca tggaaaataa agggagaaca
     6421 aaagcaattt agagagttaa caacgggtaa tgtggttatt atggggcgaa agtcttatga
     6481 agaaatcggt catccgttgc ctaatagaat gaatattgtt gtttccacca caacagagta
     6541 tcaaggagat aatttagttt cagttaaatc attagaagat gcattattat tggctaaagg
     6601 acgagatgta tacatatctg gtggatatgg actatttaag gaagctttgc aaatagtaga
     6661 taaaatgtat atcacagaag tagatttaaa tattgaagat ggagatacat tctttccaga
     6721 atttgatatc aatgattttg aagttttgat aggggaaaca cttggtgagg aagtgaaata
     6781 tacgagaaca ttttatgtaa ggaaaaaatg aattgagtaa attttggatt tagggtgttt
     6841 tcataaatat attgcttttt atgcatatat aaattgttgt aagacaaatt ccagtttgta
     6901 tggggcgata aaatcagaat ttgagagagg attgaatatg aataaggaat ggtctgaact
     6961 taataaaaca atgcaggcac aaataaaaaa gaaagatact tataagaggg gtattgatac
     7021 tttacttact ttacgaagtc agttaataca aaccttagta tctttcaaag aagaattatg
     7081 cagagaagat tttaactcaa tccccttcat aaacgctgat ggttatcata gtaagacgat
     7141 tgcttattct atttggcata ttttccgcat tgaagatata gttgtgcata cagtgataaa
     7201 tgaagatgaa caagtatttt ttgcaggcaa ttatcaagag cgtatcaatt cacctatcat
     7261 tacaacagga aatgaactca tgaaacagca gattgcagac ttttcaaaac agcttaatct
     7321 ggaagaatta tatttatata ttttcgaagt atgggaaagc actgagaaaa tgcttgaacg
     7381 gttatcttat gatgaattga aaagaaaaat accgaaagaa agaaaaggat acttagaatc
     7441 gttgaatgta gtaaacgaca atgaaaaagc aatttggctg attgattatt ggtgtaataa
     7501 agatatttgt ggactaattc aaatgccgtt ttcaagacat tggattatgc acacagaagc
     7561 ctgtttgcgt ataaagaaca agatacattc ataggcaaaa atttcagttt gtagaactaa
     7621 ggaaattgga atttaaggag gaataaagta tggttagtga ttttataaga gcagcatttc
     7681 catggatttt aatgggttta tttgtagcaa tcagttgttc ccttatgagt aaaaaagaga
     7741 aataaattcc tgtttgtatt tataaaagag aaaaaatgag aaaagtagtt ttatttattg
     7801 ccatgagcct tgacggatat attgcggacg gtaatggtgg agtagcttgg ctaaatggtc
     7861 atggaaatga caatgaaaac atcgacactt atacagaatt taccaaagat atagatactg
     7921 tcttaatggg gtggaatact tctcatcagg ttgttactga actttctccg caagaatggg
     7981 tatataataa atttacaact tatgtattaa cacataaaga gtgcaattct tcccaacaaa
     8041 ttcattttac aagtgaaaat cctgttttat tattggaacg gctaaaacaa gaagcaggaa
     8101 aggatatttg gatttgtggc ggagcaaatc ttgttcagca gttggtaagc aaaaatatga
     8161 ttgataaata ttacatttct gttattccta ctctgttagg aaatggggtt cgtcttttgg
     8221 gcaacataga cagggaaata aagttaaggc tttgtaaaac acagacttat aacggaataa
     8281 ccgatttgat ttatatgcgt agataactag agagaaacag aaaagctgtt aaaccgacgg
     8341 agcgatccga ccacgttggc gggaaaatcc ttaagatttt tccgccatgc ttgcaagggg
     8401 gcggttcgct tcggcggttc ggcgagcttg cgagccgttc aaagcccccg ttatctaaca
     8461 aggggggcac aaaaaacaag aaacactata cactaacaag cggaaaacgc tgtatttata
     8521 aggcaaaacc ccatttttac agtagtgata taaattgtac ctatatcact atgaaaattg
     8581 aatagtaaat atgagaaaga cagttgattt caaaaaataa gaaattgatt gtcgttttct
     8641 tttgcagaaa tttaagtgca ggcaattatg gtagttgtcg taattgctgt cagctcagtg
     8701 tttatcactg atggtgtgaa agatttacgg ttggagatgt tcaataagat tattggtgct
     8761 taattatttt tattgtagtg ctgatatgag aatgttataa ttggggtata aaacatacaa
     8821 ataaatttgc tgaaaaatga ggtatcaaaa tatggaaaat gaattactgg aaaacttagg
     8881 aagacttcac acaactgaac ttggcgttat tagaattaaa aagaacttat ctttgaatgt
     8941 agaaaatgta attgaatggt gcaaagaaaa aattagcctt tctaatgcgg aaatcacaag
     9001 aaaaggaaaa aactggtata taacgattga taattgtatt ataacggtaa atgcgtacag
     9061 ttataccgtt atcactgctc acaaggtaaa atgataaatt tttctataaa ggaattaaac
     9121 gcatttgcag ttattgggca ggaagtagaa ctgactaatt atcaaaaaaa gaatattcag
     9181 attagtacac agttttggag aaagtttaac agtagtttga aaaaagcgta tctttcacaa
     9241 tcaggaaatt gggtaaaata tgcttttatg gaaagaagaa atggaaaact ttattatttc
     9301 tgttctattc cccaaagaac cattacccca gagggctttc tgtataaaga aataccgtct
     9361 tataaatatt tggttgtgga gcatattggt gctatggata aaatatatga aacttatggc
     9421 aagatttatg aagaaattat tcctagtaca tcgtatattc ctataaaaga tattatccta
     9481 cactttgaaa aatacgatta tcgttttcat tggaatagtg ataattcagt tattgaaatt
     9541 tggataccta ttcaagatta gaagcaattt tatatccata cacacaaagc agttagtctt
     9601 aggattgact gctttttcta tacagatttt taatgacagg caattatcaa ttatggtagt
     9661 tgcctttttt gattggagga attgaagaat gaatgataaa aactttattg aagaactaag
     9721 acaaaagcgt gaggaatacg gagtaacaca aacaaggctt gctgttgcct gtggtatcag
     9781 ccgtgaatat tacaaccgca ttgaaaaagg aaaacagcca ttgaatgacg aattaagaga
     9841 aatcatagaa aaacagattg agcgtttcaa tccgcaagaa ccactattct tattgattga
     9901 ttactttcgt gtccgctttc ctactacgga cgcattggcg attatccgtg atgtattaca
     9961 actgaaatct aattacatgc tttatgaaga ttatggaaaa tacggatatg aaagcaaata
    10021 tgtacttggc gacatcaata tcatgtgttc catgcaggag catttaggtg ttttattgga
    10081 actgaaaggc aaaggctgtc ggcaaatgga atgttatctg ctggcacagg aacgctcatg
    10141 gtatgacttc atgctggatt gtatgacggc tggtggtgtg atgaaacggc ttgatttggc
    10201 tatcaatgat aaagcaggaa tattggatat tccaaagtta aaggaaaaat acaaggctgg
    10261 cgaatgtatg tcctacttcc gtatgcagaa agattacagc ggtacagaaa aatgcggtag
    10321 cgatttacca aagaatacag gagaaacctt atatctcggt tcaacaagta gcgaattata
    10381 tatgtgtgct tatcagaaaa attatgagca gtatgtcaag aatggcacag aaattgaaga
    10441 tacggagatt aagaaccgtt ttgaaatacg catgaagaac gaacgagcct attatgcggt
    10501 tgtagattta ctgacctatc gggacgctga acgcaccgct ttttctatca tcaatcatta
    10561 tgtccgcttt gttgacagag aggacgacaa gccaaaaagt caatggataa caaatgatga
    10621 ttgggcatgg tttgtagggg aaaacagaga gccgatacgc ttaaccacaa agccagagcc
    10681 ttacacttta caaaaagcgt tgcattggct acaaagacaa gtcgcaccaa ccataaaaat
    10741 ggtacaggca ttagacagag aaaatcgtac aacgatactg aaagatatga ttgagcaggc
    10801 agaactaaaa gacaagcata aacatttatt acaattagag aaatcaacca tagaagaacg
    10861 tatagatacc gctgttccac aagagaatga cggtattttt taatgtaatt gaaaaatttc
    10921 agatttagtc agcaaagagc tgttttcatt ccctatgtga agtgaaagaa gaaaaataaa
    10981 ttttttatta aatctgcaac aaaatggcta cttgcgtaca gatatggtgc gagaaaagga
    11041 aatctaaact ttttttgaaa ataggtcatt aaatcggggc ttgctgtccc tatatgaagt
    11101 gaaagaagaa aaaagttttg aaaaaatgac ggaaattcgt gattagtgga cagtcttctg
    11161 tgaaaagagg aaaaacatca tcattttgta ttcaaacagg cattagcagt tgagtgttga
    11221 tgtgaaaaga tgaaaatact ttgttctcaa cttaacaatt taaggtttcc gttccctata
    11281 tggtgcaaag aaaatatttc attctattgt tggcagtaac ggtatggttt gggtagttag
    11341 ggtgtgaaaa ggaaaatatt cttttttcat catcaactta gcaaaatgac attttctatc
    11401 cctatatggt gcatgaaaag aagttaaaat ttttccattt aaacttagca aatggacgtt
    11461 tgctgtacag atagtagtga aaaaggagaa aatcaaccgt tgattgccaa aatgaaccgt
    11521 tccatttgta ctaataatgg aaaaagtttt ggattttggt tacgtttctc ctcttttcca
    11581 acgcgatata taggaaagac gatttttttc tttcaatcgt tctttgacaa ctgaataaag
    11641 ctattcaata cgtttgacag acagctagcc gttgaaacaa atacgccacg acctttcccc
    11701 tgcaagagcg agcgaaaacc tatttgtgtt cttgtaaaag atttgtcctc ttttatcgcc
    11761 atgacctgta ctgtcagata atgatactcc cgtacagcca cagcttgagc attaagagcg
    11821 tcgcacgcaa tgggtacggc tacataagaa ctatgcagag gtggaactcc tgtgggctat
    11881 gacaaaagcc gttgaattgc ttagaaagat tttacagaaa gggggtatgt gttattgata
    11941 atgctgtaaa aacaattcaa aagaaaaatg gcaagtgtgg cattggcaac agaggaaaga
    12001 caaagattgt agtaaaagag catttttccg aaaagggcaa aacaatggaa gaacttctaa
    12061 ctgatgtcat gctggaaaaa gcaaagcaga caatcgcata aaatcggtgc agttgtaaga
    12121 aatagattga atgacaaaaa gtacccgtgt tatactttac ttgcaagcag gtattgtaaa
    12181 cacgggttag ttataaagga ggataactga caatgaaaca acagatttac aatactgcac
    12241 tttatcttag gttaagccga gatgatgaat tacagggcga aagttccagc attaccacac
    12301 agagaagtat gttgcgttta tatgcaaaag aacatcattt gaatgtcatt gatgaatata
    12361 ttgatgacgg ctggtcggga acaaattttg acagaccgag ttttcaaaga atgattgagg
    12421 atatagaggc aggaaaaatc aactgtgttg taacgaaaga cctttcccgt cttggcagaa
    12481 attatattat gacaggacaa tatacagaat tgtatttccc tagtcataat gtccgctaca
    12541 tagcgattga tgacggtgta gacagcgaaa aaggcgaaag tgagattgca ccatttaaga
    12601 acatcatcaa tgaatgggtg gcaagagata caagccgtaa agtcaaatca gcatttaaga
    12661 caaagtttgc ggagggggct cattacggtg cttatgctcc gttaggatat aagaaacacc
    12721 ctgacatcaa aggaaaactg ttggttgatg atgaaacaaa atggattatt gaaaaaatct
    12781 tttccctagc ctatcaaggt tacggaagtg caaaaatcac aaagcagtta agagcagaaa
    12841 aagttccgac agcgtcatgg ctaaatttta caagatacgg tacttttgca catatctttg
    12901 agggaaaacc cgaaagtaag cgttatgagt ggacgattgc tcatgtcaag gcgatattga
    12961 aaagtgaggt ttatatcgga aacagtgttc acaatatgca gtctacggta tcgttcaaga
    13021 gcaaaaagaa agtgcgtaag cccgaaagtg aatggtttcg agtagaaaac actcacgagc
    13081 cgattattga caaggaagtg ttctatcgtg tgcaggagca gataaaatca agacgcagac
    13141 agacaaagga aaaggcaacg ccgatttttg cagggcttgt caagtgtgcg gattgtggtt
    13201 ggtctatgag atttggaacg aataagacaa ataaaacgcc ttacagttat tatgcttgca
    13261 gttactacgg gcagtttggc aaaggtaatt gttctatgca ctacattcgt tatgatgtgc
    13321 tgtatcaagc cgtattggaa cgcttgcagt attgggctaa ggcagtacag caggacgaag
    13381 aaaaggtatt gaacaagata cagaaagctg gcaatgcaga gagaatacgg gaaaagaaga
    13441 aaaaggcaag tacattgaag aaagccgaga acagacaaaa tgagattgac cgtttatttg
    13501 cgaaaatgta tgaagataga gcctgtgaga agataacaga gcgaaatttt gtgatgttgt
    13561 ccagcaagta ccaaaaagaa cagatagaac tggaacagca gataacaagc ctaagagaag
    13621 aactaagtaa aatggaacag gatatgatag gtgctgaaaa gtggattgag ttaatcaagg
    13681 aatattccgt accaaaggaa ctgacagcac cattattaaa tgccatgata gaaaaaatcc
    13741 tcatacatga agcaacaacg aatgaggata acgaaagaat acaggaaatt gagatatatt
    13801 accgatttat tggaagagtt gagtaatcaa caagagtaat atttttaact aagggaaacc
    13861 ggcggtgtct atacttgggt cagtcgcaca ttgggaaaac gattcggttt tgccgcaatc
    13921 tttttccaat ggtttgagat aacagttggc tacttgacca tgctgtattt cttaactggt
    13981 gcattatcct atgcaacggg tattggtgct atacaaaaca ataaatatct gaaattggca
    14041 atcctattga ttattttctg ggctatttta ctctcacagt taaaaggaac caaatacact
    14101 tcattgattg ctcggatcgg ttttgtagct ggtatcttgt tgccagcatt agtcttgttt
    14161 ggcttaggga tccattatgt cgcttcaggc gctccactac aaacgatact gtctatgaaa
    14221 acattgattc ctgatttttc gaaattgcct acgctggttg tttttgtttc ctttatttta
    14281 gcatatatgg gcgtagaaac atctgccagt catgcaaatg aaatggaaaa ccctaaaaag
    14341 gattatccat tagcaatgtt tgtattggtt attctggcaa tcattttaga tacttttggc
    14401 ggattgaccg tcgctactac agtacctcaa catggtttgt ctcttaatac aggggtgatt
    14461 caatcgttag aattcctatt aagacacatt gatccaaatc ttgcatggat tgcgaaaatt
    14521 cttgcgattc ttgtttgttt aggtgtcatc ggagaaattg cttcttgggt aacctctcct
    14581 tcaaaagcac ttcacgtagc agcagaagaa ggattacttc ctgaatattt tgcaaaagaa
    14641 aacacacacg gtgttcctgc tcatttgatg atcgcaaatg ggatcgttgc aacaatctgg
    14701 gcagccgtct ttacattaag cggcgggggg aataatcttt catttcttgc agcgatgtca
    14761 ttgactgttg taatctacct gatgttgtac tttatgtttt tcgcgggcta tttgaagctg
    14821 gtttttaaag atgacagtct tgaaagagcc tatcaggttc caggcggaaa agttgtaaaa
    14881 gtaatcgttg cttgtttagg tcttttgact tcactttttg ctttttgtat ctcatttgtt
    14941 ccacctgcta gtatcgcagc tggacagcat gggatttatg aaacgattct gattgtttct
    15001 tatcttatcg tcttagttat tccatttacg atctacgcat gccgtcataa attccagcat
    15061 gcagaaaaat aaaaaatgaa agctggttat tcaaatggaa gtaaaagaat tagaacaatt
    15121 gattggaaaa aatttccact attatcaaac aggacaagtg gcggattaca ttccagcatt
    15181 agctgaagtg gatcccaaac aattaggtat ggcgatttat gatttggata caaaacaact
    15241 gattgaggga ggagacgccg atgtgcgctt tgccatcgaa agcatgtcaa aagttcccgt
    15301 attgttatta gcaatcaaag acaacggaat agaaaaagtc tttcaaacaa tcaacacgga
    15361 accaaccggt tttgccttca attctatcat gaatatggaa atcaatcatc gcaaacatcc
    15421 aatgaatcct tttgttaatg caggagcgat tgcaacaacc tcgttgattg ccggtaaaga
    15481 tgcagatgaa aaatttgagc gaatcttgtc atttatgaaa gagatctgtg atgatcctaa
    15541 tatcacattg aatgaagaaa tctatcattc tgaatcaaga acaggtgata tcaatcgctc
    15601 tcttgcttac tatatgaaag gtaatcaaat gatcgaagga gacgtaccgg agatactcga
    15661 tgcttatttc agacaatgct ccctcaatgt caccgctaca ggcatagcaa aattagctgc
    15721 tgtgctggca aataaaggaa ttgctccttg gaatggcaaa caaatcatta ctgaagaaag
    15781 tgctacaatc gtcaaatcaa ttatgacaac tgctggtttg tatgatgaat caggagagtt
    15841 ttccgtccat gttggtgtac ctgcaaaaag cggtgtaggc ggcgggttga tggcagctgt
    15901 gccaaatcgt tacggcatag gtgtcttcag cccggcacta gatccatttg gtaacagcgc
    15961 agctggtatc caattgttga aagatgtagt caaagaacta gacgctgaca tctttgaata
    16021 accattcttg aaagaggctg gggtaaaagt ccaaacggct caaagctacc tacaatgagg
    16081 ctgaaattgt gagcttgttt gacttttgtc ccagtttctt tttttattgg tttttgaaag
    16141 ggcttttcta aataaaaagg aaacaaaaat acgatttaca gatatgatta aataaaatca
    16201 taagaaaaac tggaggcgtg tatcaggaat gctggaaaat tacatcgagc gaaatatatt
    16261 tagaaaagtg tatctgtgtg aacaattatt tgaattccaa gaaatagaca tcgaacaaac
    16321 agctatttct ctaagggtga ctacaccaac gatccttcac gatctagaaa gtctagccga
    16381 gtgtctagaa tattgtataa aagaacaagt aagagagaag cataagtata aactcgtatt
    16441 caaacatggt attgctcttt ctgagctcac acagtttctg tacggtcaat cttatttttt
    16501 aaagttttta agttattatt ttaatggtat attcacgagt acagaactgg ctgatcttga
    16561 atttatttct ttgagtaaag tatatacaat caaaaaaatc gtattggatt tttttaaaga
    16621 aaatgattat ttgaaaaata aagaaatcat tatcccagaa tttgactcgc ggaacatctt
    16681 gctagcttta gtacgttatg tcaattggga aggctatgaa aataaaaatc cgtatgtaga
    16741 agaagcttgt aacgagttga ttgattatgt agagactcat ttttttaaaa gaagatattc
    16801 ggaagatgaa aagtccttta tcatacgaga aatagagatc gcaatcggaa gaaaggcatt
    16861 tccccttgga ctgaaagaag aagataagaa aagcgcagaa acgaagccgt tatttcaatt
    16921 agtctgtcaa ggattggaag agcaaaaagg aattctagac ttacaagaag aagatgtcta
    16981 ttatattttt tctttgttca acagtagaaa ttataccaat gagaacatgg agctgttaag
    17041 aaaagatttc gaagttgttt ataaaaattt tgttctcaat gacctatcac tgaatgaatt
    17101 gattttacag attattagta tcgctgaaat cgacgatgca gaaaatttta ttttcaagca
    17161 atccttttta caatttgtcc gtacgttgtg ggcagatgga caagtatttt taccggaaag
    17221 gatctatctt ctatcagaaa aagaacaact tctgtacgga aaaattgtag aaatattgga
    17281 agagtggaaa aagaaaaatc aaatccaact aagatggaat gaaaatttca ttcgaaaatt
    17341 cgtcaaaagt ctttctttga tcaacagtga acaagcgggg agacaggaaa tagaaatttt
    17401 tgttgtttca gaaagttcag tcaaacaatt tttttatcga acccaatttc atttgtatgc
    17461 ggaagaaggc atcgctgaaa taaatcctat tttatttcgt tcattagaag aattgcctga
    17521 tgaatgtcta tgtgcgaaaa aaagagtggt tttgtgcgat gctgctagct atcaaaatgg
    17581 attagaaact gaaaagacaa agatctatcc aatctcatta aaaggtgcaa acatccattt
    17641 gtatcatatt gctcaggaac ttcacctatt aaaaaaacat atttcttgat gagaccttaa
    17701 ttaggagacc ttctacaaag ctttttaatt gtctgtagaa ggtttttatt tgagtcctga
    17761 ttcgtgcgaa gatctactta tataacaagc tttctctgaa atttttttaa aatgctattg
    17821 acttagagtc aactctaagt agtagaatag ataaagtgta acaaatctat tttcattaaa
    17881 agaagatagt acggaggaga gaatgtatta tgagtacagt attacatgta ttggatgcaa
    17941 tcaatagccc cgcagatgtc aaaaaattat ctgttgagga aatgaaacag ttggcagaag
    18001 agatgcgcca aaaaatcttg caaaaggaca gcgatgtagg tgggcacgtt ggtccgaatc
    18061 taggtgtagt agaattaacg attgcgtttc attatgtatt tgattcacca aaggataaaa
    18121 tcgtttggga tgtttcccat cagtcttatg gtcataagct tttaactggt cgaaaaaatg
    18181 gttttgaaaa aggacattac cgtgaagtga gcggatattc caaccaacat gaaagtaaac
    18241 atgactattt tacagtgggg cacacatcta catctatcag cttagcaaca ggtttagcta
    18301 aagcgagaga tctgaagaaa gaatcaggaa atgtggtagc atttatcggt gacggctccc
    18361 taagtggtgg cttagctttt gaaggattga acaatggtgg tgttttacaa tccaatctaa
    18421 tcgtattagt aaacgataat gagatgtcta ttgatgagaa tcatggcagt ttatataaaa
    18481 acttagctga gcttcgtcaa accaacggta aaagcagcaa taacctattt aaagcaatgg
    18541 gatttgatta tcgttacgtg gataatggaa acgatctgga aacggtgatc cgtttatttg
    18601 aagaagtaaa agatattgat catccgattg tacttcacgt ccatacggaa aaaggtcgcg
    18661 gttatcagcc ggcaatcgat aataaaatga aatatcattg gcatgtacca tttgatctgt
    18721 ccaccgggga ggcaaagcaa gtaacttctg gagaaacatt taatatgatc atcatggatt
    18781 atttggataa gaaaatgcaa acaagtacag ctcctattgc cgcagtcaat gcagcgatac
    18841 caggcgcctt tggactgaaa acattccaag aaaaacatcc agatcattat tttgacgtgg
    18901 ggatcgctga acagcactct atcactttcg cttctgcttt ggcttctcag ggagtacgtc
    18961 cagtcgtctt ccaatcaagt actttcttgc aacgggcata tgatcaatta tcacatgatt
    19021 tagcgatcaa cgagaatcca gtgattattt tagtcggtgg cggaacgatc tcagctagtg
    19081 accgaacaca ccaaggaaca tttgacattc cttacttatc aagtatcccg aacatcaaat
    19141 atcttgctcc agcaacaaaa gaggatatga tctctatgct agattgggcg ttcgaacaaa
    19201 cagcgcagcc tgtagcaatc cgaattccta cacatggtgt agaacatggt acagctatcg
    19261 caaatgatta tagtattcca gcctatcaaa cagtaaataa tggaggaaaa gtagcaattt
    19321 tagctttagg cggttttctt gaattaggaa aagaaacagt aaaagctttt agaaaaaaag
    19381 gaatcgaagc aacgttgatc aatccaggaa cgatcacaga aaatgacgta gaaacattag
    19441 ataaattaaa agaaacacac gaattagtca tcacattaga agatggtagt ttgtcaggag
    19501 gatttggcga aaatatcagt cgttattatg gtgattcttc aatgaacgta ttaaattttg
    19561 gtgcagagaa agaattcacg gatagcgttc ctgtagggca gctttatgaa cgttatcatt
    19621 taacaccaaa acaaatcgtt gaagatagtc tgcgtgtctt gaatattcaa taattcatta
    19681 tgctcaccat ccagataatt gtttatacta gtatctggat ggttttttca ttataaaaag
    19741 caaaggggtg gatgttatgt atcagcaagt agaagaatat gtcaaaaagt tccaagaaaa
    19801 atatcctagt tatcaatcag aaaaattagg tttcttttca tttggggata cagaaaaaat
    19861 ggcagacgag ttgagcgaac tagttgtaaa aaagataaag actggtacat caagtggtta
    19921 cgatctgtat aaacaagaga atgagccttt accaaaagtt ggtcaattag acgtggtcct
    19981 gaatggaaaa aatgaaccag tttgtatcat caaaaatata aatgtgacca tcttgccttt
    20041 tagtgaagtc acgaaagagc atgcttggaa agaaggagaa ggggatcgga cattagctta
    20101 ttggcggaaa gtccatgctg agttttttaa acatgcttat aaagaagcgt tgaacataga
    20161 atttacagaa gagaagctgg tcgtatacga agaatttgaa gtaattttct tttagtaaga
    20221 aaggtctgct gaaagaaata gctcattatt gtctcctgaa tagaaaaggg ttacattttt
    20281 atatgaagct gtatttttat ataacattac tggaggagat attgtggata cactggaaca
    20341 aatcaaaggc ggagtcgtcg tttcttgtca agctttggaa aacgagccgc tacacagttc
    20401 ttttattatg gggagaatgg ctttggctgc aaaagaaggc ggagcagttg gtattcgagc
    20461 aaatacgaca gaagatatca atgaaatcaa gcgaatcgtt gatttaccgg taatagggat
    20521 tatcaaaaga gattacgatg ggtcagaagt gtttattact gcgacagaaa aagaagtgga
    20581 agaacttttg gagacgcaag cagaaatcat tgcactggat gcaacttctc gtaaacgtcc
    20641 gacagaaaaa acaactgctg aacttgtcca aatgattcac gaacacggtc ggttagctat
    20701 ggcagatatt tcgacttttg aggaagcgct tcaagcgcaa gaagatggtt ttgatctttt
    20761 gtctacgact ttagcaggct atacagaata ttcacgaaag acgcagacac ctgattttga
    20821 tttattgaat caaatcatag aacaagtcga tatcccagta attatggaag gacatactga
    20881 ctctcctgaa caagtagaga aagcatatga attaggtgct ttttcagtcg tagttggatc
    20941 tattatcacc cgtccgcaat tgatcactaa aagatatgtc gaagccgcaa gtaaagcaaa
    21001 taactaaaaa acacgcacgg cacagattct tgacaaaaaa gaaaaattga tagatagttt
    21061 aaagcagatt ctaagaagat gaaaaaagca ttacttttca ttttgtcttc aagatctgct
    21121 ttttaacgaa ttttatagaa agaaggcgaa accatgtttg aacggagtcc ttcagaattg
    21181 acagaacgtg aaaattacaa gttgctgatt ggttcagtca tccctagacc agtagcagta
    21241 gtaacgacta aatcagcaaa agatatagtg aatatcgcac ccttcagtta cttcaatatc
    21301 gtcagttcga atcgacccat cttatccttg gcgatccaga gaaaacaaga tgcagtaaaa
    21361 gacacagcaa agaatattct tgagacaaga gaagctgtta tccatatcct tgatgaggac
    21421 aacgtagaag aagtaaataa aacagcagcc aatctgccta atgaggaaag cgaactgtac
    21481 ctgactgact tgactttaac tgattcagta atcatttcag taccagcatt gacagaagca
    21541 aaagttcgtt ttgaaacatc cttatatgaa catgtcgaga tacggaataa aaataaagta
    21601 acagctgatt tatttttgct agaagtacag aaatatcatt taaatgaaac agtctatgat
    21661 gataagacag gaaggatcga tccaagaaaa ttgaatgctg taagccgttt ggcaggaaat
    21721 gattatgcag caataggaga aattttcacg attgcacgtc ccgaataaaa aggagcacta
    21781 gttatgttaa aaataagcta taaaccatcg acagattcaa aagaaatgaa aaaagaatat
    21841 gaaacagtga atgattttct gcaagggcag tacttagaag ttccgccatt gcaagaccat
    21901 tttgtcgtta ctactgttac tttagatggt aaggaaatag aaatgccaga tcaaacgatt
    21961 agcggattgt ttaattactt taacaaataa atatttattc cgaaaagtga aaaaacatat
    22021 aaaaaaacac ataaaactaa aaaattatca aagaatcctg gtgcaactga aagaatttgc
    22081 aacgggattc tttcaactta tttgttattt ttttctaaaa aatattaaag attgttaaat
    22141 ttcactattt catttcaaat tccattgcct aatcattagg aaaagtctat aatgaactcg
    22201 taaatagaat atagtaataa ccttgttagg tgaggctcct atacaaacat aggctgttgc
    22261 ccagaaacgt cgaaagtcgc caatgggtaa aacagaaact gttggattaa ggctttttcc
    22321 aatagctaag aatgttttct ttacgttgta tagtgctaaa actcggacga tgagatgatg
    22381 ctaggtcaga attcttgttc gaaaaggttt ctgacctttt ctttatattt ttgtgactga
    22441 cttatttgat gagacaaact cgctcctcac ctgacaagtg gattgctgtg tgaggaggag
    22501 atgcggtgaa aaaagatcga ttggtggatt ttgggtcctt atttgacttt gtccatgatc
    22561 ggtcttttag aagtatacag tgccagttct tatcgtttat tgcaagccga tgaaaataca
    22621 aaaagtctat tattgcgtca actaattttc atatttttga gttggagcgt gatcttctta
    22681 gctcgttcag tcaaactaca ctatttactt caccctaaaa tagcaggata cggtttagcc
    22741 ttatcgattt tctttttagt attagtaaga atagggatat tcggtgtcac tgtcaacggc
    22801 gcacaacgtt ggatctctct gtttggcatt caattccagc cttctgaact ggcaaatctt
    22861 tttttgattt tttatttaag ctggtttttt cgtgacggaa atagtagccc aaaagatcta
    22921 aaaaaaccat tcctgattac agtaggtata acttttctga ttttatttca gccaaagatt
    22981 gctggagcat tgatgatcct ttcgattgcg tgggtcatat tttgggcagc ggcggttcca
    23041 tttaaaaaag ggatctatct aatcgttact ttttctgcat tgctgattgg agcagcaggc
    23101 ggggtattat atttaggaaa taaaggttgg cttccacaga tgtttaatca tgcttatgaa
    23161 aggatcgcga ctttaagaga ttcttttatc gatagtcatg gtgcgggcta tcaaatgacc
    23221 cattcgtttt atgcactata taatggtggc atatttgggc ggggattagg aaatagtatc
    23281 acaaaaaaag ggtatcttcc agagacagaa acagatttta ttttttcgat tattacagaa
    23341 gagcttgggc taatcggtgc attgtgtgtg cttttcttat tgttctcatt atgcatgaga
    23401 atcttttgtt taagcagtcg ctgtaaaaat cagcaagctg gattgtttct tttaggattc
    23461 ggaactttgc tattcgttca gacgataatg aacgtgggaa gtatcgcggg gctgatgcca
    23521 atgactggtg tgccattgcc atttgttagc tacggaggaa caagttatct gatcctttct
    23581 ttaggaatcg gaatcacgtt gaatatttct tcaaagatac aggccgaaga gttggcgctc
    23641 tatcgacctg aaaaacaata aagagaaact gagaaactct cagtttgaat tatcataaag
    23701 tacaatcttt tatttttcaa gcgagaggtt cttttagaaa gaggaattcg caatgaaagt
    23761 atctcaaaaa atcatattat ctattttgtt actgcttaca ttagtagttg gctatttttc
    23821 gattgagttt atccatggat tttcgtctgc aaaacagagt tcaactgtga aaaaggtaga
    23881 gccgaaaagt atccctacca cactaaatgt ggctttgatt ggttcagatg ctcgttcgaa
    23941 agacgaaaac ggtcgctcgg attcacttct ggttgcacaa tacaaccaga aaacacaaca
    24001 agcaaaactg atctctatca tgagagattc atatgtcgat attccaggtt acggaatgaa
    24061 taagataaat gcagcttact cttatggggg agttgattta ttaaatcaaa cattaaagga
    24121 aaatttcaaa tttgaagctc cctattatgc aagtatcaca tttcaagatt ttatcgattg
    24181 cgttaatgaa ctgtttcctg gtggagtcaa gatcgatgca gaaaaatctc tagatttaga
    24241 tggcgtatat ataaacaaag gagagcaagt gatggatggt aatactttac tccagtatgc
    24301 tcgatttcgg gaagacaaag aaggagactt cgggaggatc agaaggcagc agcaagtgat
    24361 caaagctatc tctcagcagc tgaaagacgt aacttcaata ttcaagctac ccaaagcggt
    24421 tgggaaatta cttggtagta tccaaacgaa ccttccagaa agtgtgcttc tggattgtgg
    24481 tatggatttc ctcaaagaca tatgttagaa taaacaggta taaatagtga aataaaggaa
    24541 tgacaagcaa gagaaggagg aaaaaatgaa aagaagtgac aagcacggca aaaatcgaac
    24601 aggcgcttat attgccggcg cagtgatctt aatagcagct gcgggtggcg gttattttta
    24661 ctaccagcac tatcaagaaa cccaagcagt agaagctgga gaaaagacag ttgagcaatt
    24721 tgtccaagct ttgaacaagg gagattataa caaagctgca gaaatgacat caaaaaaggc
    24781 ggcaaataaa agtgcattat ctgaaaaaga gatcttagat aaataccaga atatatacgg
    24841 tgctgctgat gtcaaaggac ttcagatatc gaatctaaaa gtagataaaa aagacgattc
    24901 tacttacagt ttttcatata aagcaaagat gaatacctca ttaggtgaat tgaaagatct
    24961 ttcttataaa ggaacattag acagaaatga tggtcaaacc acgatcaact ggcaacccaa
    25021 cttggttttt ccagaaatgg aaggaaatga caaagtaagc ctgaccacac aagaagcagc
    25081 aagagggaat attatagatc gaaatggtga accattagca acaacaggca aactaaaaca
    25141 attaggagtc gttccaagta aacttggaga tggaggcgaa aaaacagcca atatcaaagc
    25201 gattgcttcc tccttcgact taacagaaga tgctatcaat caggcgattt cacaaagctg
    25261 ggtacaaccc gattactttg tcccattgaa aatcattgat ggagcaacgc cagaacttcc
    25321 agctggagct accattcaag aagtagacgg cagatattat cctttgggtg aagcagctgc
    25381 tcagctgatt ggttacgtgg gagatatcac agcagaagat attgataaga atccagaatt
    25441 aagcagtaat ggaaaaatcg gtcgctcagg tttggagatg gcttttgata aggatcttcg
    25501 tgggacaaca ggtgggaaat taagcattac agatgcagac ggtgtagaga aaaaagttct
    25561 gatcgaacat gaagttcaaa atggcaaaga tatcaaattg acaatcgatg cgaaggcaca
    25621 aaaaacagct tttgacagtc taggaggaaa agctggatca actgttgcga caacgccaaa
    25681 aaccggtgat cttcttgcgc ttgctagctc tccaagctat gatccaaaca aaatgacaaa
    25741 cgggatctca caagaagatt acaaagctta tgaagaaaat cctgaacatc cattcatcag
    25801 ccgatttgcg acaggttatg ctcctggatc tacgtttaaa atgattacag cagcaatcgg
    25861 tctcgacaac ggcactatcg atccaaatga agtgttgacg atcaacgggc ttaaatggca
    25921 aaaagacagt tcttggggat cttatcaagc aacgcgtgtc agtagtgatg tatcacaagt
    25981 agacttaaaa actgctttga tctattccga taatatatat gcggcacaag aaacgttgaa
    26041 aatgggtgag aaaaaatttc gtacaggctt agataaattc atttttggtg aagaccttga
    26101 tttgccaatt agtatgaatc cagcacaaat ttctaatgaa gatagcttta actcagatat
    26161 cttgctagct gatactggat atggacaggg cgaacttcta attactccta tccagcaagc
    26221 agcaatgtat tctgttttta ccaacaatgg cacacttgtc tatcctaaat tgattgcaga
    26281 taaagagaca aaagataaga agaatgtcat cagcgaaaca gcagtacaaa cgatcgtgcc
    26341 agatctgaga gaagttgtgc aagatgtaaa tggtacagca cattctcttt ctgctttagg
    26401 gattccgttg gcagcgaaaa ctggtacagc ggaaatcaaa gaaaaacagg atgtaaaggg
    26461 gcaagagaac agtttcttgt ttgctttcaa tcttgataac caaggttata tgatggtcag
    26521 catgttggaa aataaagaag atgatgattc agcaaccaaa cgagcatcgg aactattgca
    26581 atacctcaac caaaattatc aataaaaaat tgctttttaa gtacagtaaa aggactgtgg
    26641 cgttatcgtc acagtccttt tttcaaataa acggttttca cgatgtctct ttcacaactt
    26701 ctttttgatt tactcacact tcataaactt tttttgtaaa atatttgaga acaagtggag
    26761 aaataagtgt acttaataaa atcacgataa ctaaaggtga atagtactgt ggttcgatca
    26821 attgactttg ctgtccaatt tgtaaaatga tcaaagccat ttctccacgc gaaatcatac
    26881 cagcaccgac catcaatgaa ctatgttgag aaaaaccggc aatctgagca ccaaaataac
    26941 ctccaagcaa tttggtcaaa atcgctacaa gcgtcaatat agaaataaag agtagttgtt
    27001 cactaaagtc agaaaaatca acttctaatc ctacactgac aaaaaatact ggtataaata
    27061 ctgcatatcc taaagcctct acattgtggt atacttcttc tttaaccttt gtctgactga
    27121 cagctatccc agcaaaaaaa gcaccaatga cagagctaag cccaacaaga tccgctacgt
    27181 aagacattcc taaacaaata actagcgata cgatgataat agaagaattt gcgtacactt
    27241 tttctgcaaa tgaaagtagg aaaggcgcaa tccatttgac taataagaaa ataaaaacaa
    27301 aataaattag ctgttcaatc aaaacaagcg gtaaagaagc attgctagaa gcttcccccg
    27361 ttagaaaaga taggctgaaa cttagaacta aaacgactaa aatgtcatct accacagaag
    27421 cacccaaaat tgttgatcct tcttttgtat tcactacgtt tagttctttt aatacttcta
    27481 ctgaaatact gacagaagtt gccgcaagaa taatcccaaa gaaaatcgct tcatttcccg
    27541 aaacttggaa tgctttgcct gtcaaccagc caaaaacaac cgggaagatg atcccaagca
    27601 aagcaacgaa cataccaggt cggaaatatt ttttcaaaag agataaatca ctttccagac
    27661 cagctaaaaa cattaataag atcacaccaa tctccgaaaa gtcatggact agaatatcag
    27721 gtttgaccca attcaatcca gcttggccta gcaaaacacc aacaagtaat tgtccaatca
    27781 ctgctgggat acctaatctc cgcgagatat gtgagccaat cgttgttgaa atcaatatca
    27841 ggcataaaat accaataaat tccattctca tcattccttt gtataaaata tagcccgaac
    27901 ttagcataac atacattatt gaaaaaatag gaaaatatac tcacaaaaaa accaacaatc
    27961 caaaagattt ttttggattg ttggttttta tacggtctat tttaataact aaaaatgatt
    28021 aacgtatagt catttttctt attctgatga aattgataat ctcctggatg cccatgaaaa
    28081 tcaaaataaa gccgaatatt tggaatagaa gcatcaaact tttgaatgga ttgaacaata
    28141 agacgaatcc gccaatcaac aacagaatac tactataaac actccaactt ttagcttttg
    28201 tattcatgct gaagaacaac tggaacaagc tgttgatgat aacagctaat ccaagaagaa
    28261 tcggcaggat agaaacgatt gcaggtgcaa aagcatagac gatcagagct aagatcagga
    28321 aaaaaagacc actgaacaga ccgatactcc aagaacctgt tttcctttta aaacggtaag
    28381 cctcaaaaag attcaacaac ccaagcaaaa caagataggc ggtgatcaga taaccgataa
    28441 aatgaaaaac agcagaaggg tttagcacaa tcgcaatccc agaaataata taaacagcag
    28501 ctcttaataa ggcgtatttt tgaatatttt gtttaatcgt ctcaaacata taagaaaacc
    28561 tcctttgact tattttaacg tgaactagtc attttaccaa attaaatgtt acaaaatgag
    28621 cgaaggagaa gaatatctct ggaaaaatca acttctgagg atcttttcca tttttttgcc
    28681 ttttgctagc tcatcgatca ttttatctaa ataacgaatt tctttcatca agttatcctc
    28741 gatgtcttct actcgtacac cacaaacaac acctgtaatc aaggaacgtg aaggattggg
    28801 gacaggggct tccgcaaaaa attgttcgaa agtcacttgt ttttgtagtt gatattctag
    28861 ttctgtttgg gaataacccg tcagccaaca aatgatttca tctacttcct cttttatacg
    28921 atcttttctc tccgcttttg ctacatacat aggataaacg cttgcaaaac ttgtcgtaaa
    28981 aatacgattt tgcgccataa tcagtcacct ttcttttttt caaattattt actacttata
    29041 gtatataaga aaaagagaag aaaaagcgat tattcaaaaa aacaaaaagg attgtgacaa
    29101 aattcttgtc accatccttt tttccgctct ctgacttttt acaatcttca tagctcaagt
    29161 gcgcatcaga taatcgaatg ctcctaaagc tgcagtagct cctgaaccca ttgaaacaat
    29221 gatttgtttg tatggactat ctgtacaatc accagctgcg aaaacgccgg ggatattcgt
    29281 tgcgccattt ttctcggtca ctatttcatt tcttggattc atttcgatcg ttccatctag
    29341 ccaatccgta ttagggagta agccgactag aatgaatact cctgaaacag ctagtgtatg
    29401 catctccatc gtacggcgat cgatatagga gagagattct acctgattcg taccgctgat
    29461 ttctttcgtc gctgcatgtt tgataacagt gacattcgca agagagacta gtttatcctg
    29521 taagatttga tctgctttta attctggtaa gaattctaga acatatacat gttttgctaa
    29581 cccagccaaa tcgattgctg cttcaacacc agaattacca ccaccgataa cagcaatctc
    29641 ttttccttta aataaagggc cgtcacagtg tgggcaataa gcaattcctt tatttttaaa
    29701 ctctttttcg cctggtacat tgatagaacg ccagtgcgca cctgtcgcga tgatggcggt
    29761 ttttgcttta agtgatatac cgttagctaa gccaatatta ataaaatgtt gctctttatt
    29821 taaggaaacg gcctgttgat tcatcataat gtcgataggg taactacgca catgactttc
    29881 tacttgctgc atcaattttg gaccttctgt gtaagaggta ccaatcatat tttcaatccc
    29941 tagtgtttca acgacttgtc cgccgaaaga atcagcgaca agtcctgtac ggattccttt
    30001 acgtgctgca tagatagctg cactactagc tgctggtcca ccgccaatca ctaatacatc
    30061 ataaggttct ttttcaaaca actcttcttc aatcaaaggg ccagtgattt tttcaacaat
    30121 ttgttcgatc gtcatgcgtc cgctactaaa ttcttctcca tttaaaaaca cagttggcac
    30181 tgccatgatt tttttatcat cgatttcttt ttggaacatc ccaccttcaa tcatcgtatg
    30241 agtaatattt ggatttaata cagctaatat attcaatgcc tgtacaacgt cggggcaatt
    30301 atgacaagtc aagctaacat aactgtcaaa atgcaatgtt tgtgttattt ttttgatttt
    30361 aagactcaaa gattcactga ttttcggtgc ccgtccacta atttgtaaca tagccagtaa
    30421 aaaagaggaa aattcatgac cgagggggat accagcaaaa acgattccac tttctttgcc
    30481 aactggattg atagaaaaac taggtgtgcg catcgaatct cttttttccc aagagatttt
    30541 aggagacatt tctgctattt ccttcgtaaa ttcagctagt ttttgactat tttcactatt
    30601 atccaaacta acagaaaaaa caataggaga ttcaatcagt gctaaatatt gttcgagatt
    30661 ttgtttagtt tctttgtcta acatatccac cacctaaatc tttccaacaa gatcaaaact
    30721 tggtttcaat gtttcgccac tttctttcca ttttgccgga caaacttcac ctgggtgggt
    30781 acgtacatat tgagcagcgc gaatcttatc aatcagtgca ctagcgtcac gaccgattcc
    30841 atctgcattg atttccatag cttgaacgat tccgtctgga tcaataataa atgttcctcg
    30901 ctgagctaat ccttgctctt catccaaaac atcaaaaata cgagaaatct gatgagacgg
    30961 atcaccgatc atcacgtatt cgattttacc gatagcatct gatgtatcat gccatgcttt
    31021 gtgagtaaag tgggtatcgg tagagcaaga aaagacttca acacctaaag atttcaatgt
    31081 actgtattgt tcttgtaagt cttctaattc agtaggacaa acaaaagtaa aatcagctgg
    31141 atagaagcaa agaatactcc agttccccat aagatctttt tcactgactt ctaaaaattc
    31201 tccttgatga taagcatgtg cattaaattc ttcgattttt ttcccaatca atgacatagt
    31261 aaaacctcca ataataatta tttatttata attattgtaa tttagttgga gttgcaaagt
    31321 caatggatat tttgttattt aataaagatt actcaaaaac gaaggttaat tataaaaata
    31381 gaagaggtcg caagaaaatg ctactgctgg aaatactcgg gataacgttg agtaacagtt
    31441 tcctgttctt tcagcatcat gtgtaagtgc aatcccgttt gaaatcgagc ttcttctggt
    31501 tttttatcaa ctaaagcctt gagtaaatca taatgttgtt ccatgatcgt ttcccatgga
    31561 agcccctgaa tggtcactcg taaccagcgg aaacgttcta aatgggtatt atggtcatct
    31621 aaccagttcc aaacttcttt tcttcctgca atttcgaaac aagcttcatg aaataaatta
    31681 tctgcacgga aaaaagcgcg ttcgtcattt attttgactg ctttttcttg ttcttctaaa
    31741 atcgtttcta gcactattcg tgtttgtgtg tccaatttgg aacaacattc aatcatgatt
    31801 tgctcttcca actgttctcg gacaaagcga gcattttctg cagaaacaag attaattttg
    31861 gaaacatacg taccactttg aggtatcgta tacacgagtt cttgctgacg tagttgaatc
    31921 aatgcttcgc gaatgggagt ccggccgata gcaagatgtt cctccagtgc cttttcagat
    31981 attttccttc caggttctaa gtcagcatag ataatttgtt tacgaatcgc ttgataagct
    32041 tgtgattgca agctgctttt catctttatt cctccaaaat catttctatg aacgtagtat
    32101 aacagaagag gtctgaaaaa caatctggta tgtcacatta actagtaaat ttgtataaat
    32161 agtaaaattt tggttgacat agcgattttt attgcataaa attcacttga atacaaaaac
    32221 taatatgtta gtttaggagg ggaaaaatga ttgatttaaa caactggagg aactttatcc
    32281 ctgaattatc tcaaaaagaa gtagaaatac ctcattttga ccgtgcatca ttaagagaaa
    32341 atggacaaaa aaatcctgtc tggatccatt tcggtggcgg aaatctttat cgaggatttc
    32401 atgcagaaat cgctcaacgt ttagcggatc taggcgaatt gtccactggt gtcattgttt
    32461 gtgaaacatt cgatgaagaa ataattgaaa gggcttacca agattttgat gatttgattc
    32521 ttgaagtggt catgccaagc agtggagagt tcgtcaaacg tatattagct gcgacagctg
    32581 acagtctgta ttgtcatcca gattgttctg aacactttga taagatgatt cgacactttg
    32641 aaaatcctag tttacaatta gttacttttg ctattactga aaaaggttat cgattgaaag
    32701 atacaaataa taaatatata ggaccgattg cagtcgatat aaaaaatggt ccaaagaagc
    32761 catcacatac aatgagtatt cttgctgtgc tactttataa acgtttttta tctggagctt
    32821 ggccgattgc acttgtctct acagataatt tttcacaaaa cggtagtcaa ttacgtactt
    32881 ctttgctaac gatcgcaaaa gaatggcaaa aggaaggtta tgtacaaaat acatttatcc
    32941 aatacttatc gaatgaagaa attgttgcgt ttccatggac gatgattgat cgtatcaccc
    33001 cgaatccttc cttgtcagtt agcaaaatgt tggcaaaaga gggcttttca aatatgtcga
    33061 ttttccaaac cgcaaaagga aataatattg ctccatttgt caatacagag gacatccatt
    33121 atttaatcat ggaagatcat tttcccaatg gacgtccgaa attcgaaaaa gctggggtat
    33181 tcttgactga tcgtgcaacg gtagataaag cagatacgat gaaggtgacg acttgcctta
    33241 atcctttgca tacgtcttta gctattatgg gttgtttact ggggtatagg agcatagctg
    33301 aggagatgaa agatccagat ttatcgctgc tagtttctga aatcgggtac aatgaaggcc
    33361 tcccagttgt ggagtctcca ggtatcattg atccaaagat ctttctggaa gaagtaatta
    33421 ctgtgcgctt ttctaatcca aatattccta atatgcctca gcgaatcgcc acggatacct
    33481 ctcaaaaggt ggcgattcgt tatggtgaga cgattaaaaa atatatggaa atagaagtta
    33541 aagacccgca gacacttgta ttcataccat tgactctcgc tgcttggctt cgatacctta
    33601 ttggcattga tgatcaagga aaaccattca tcccgagtcc agacccacta ttgacagacc
    33661 ttcagcataa gctttccgat attcaactgg gtacgcaaga tacatcacat attcatgaga
    33721 aaatggctcc tattttgtca aataaagaaa tttttggtgt agatctttac caagcagagc
    33781 ttggcagaaa aatagaagaa atgttcatca agatggtagc aggaccaaat gccgtacgaa
    33841 aaacattaca ggattactta caagaacatg gaggaaattt atcatggaaa tgacttttag
    33901 atggtacgga tcacaggaag aaaagattac cttagatgaa atcagacaga ttcctgcggt
    33961 caaagggatt gtaggcacat tgatggatat accagtagga gaggtatggc ctagggagag
    34021 gatcaaagaa ctaaaagaag aaattgagtc tcgtgggtta acactaaaag taattgaaag
    34081 cgtcaatgtg catgatgcca ttaaaattgg attaccttcc cgtgagcagt atatcgaaaa
    34141 ctataagcag acaatccgaa acttggcaga atatggaata gaagtcatct gctataattt
    34201 tatgcctgta tttgactggg tgaaatctga ccttgactac cgcttagaag acggctcatc
    34261 cacgttagct tttatatctg atgatattcc agatgatcca agagaaatcg tcgcgcgcat
    34321 cgaacattcc agcaatgaat ttggattgcc gggatgggaa cctgagcgct tagctcctat
    34381 caaatccttg cttgaagcct atgcatcagt agacgaagaa aaacttcgag aaaattttgc
    34441 ctattttctc caatcaatca tcccaacatg tgaagaggta ggggtcaaaa tggctgtaca
    34501 tccagatgat ccgccatact cgatttttgg attagctcga atcgtaaaga atcgagaaga
    34561 tttagattgg ttgtgtcgca tagtagacag cccttataac ggaatcactc tttgtacagg
    34621 gagtattgca gaagatccag aaaatgatgt atatgggatt ttagcagaat tttgccaaag
    34681 agatcgaatc ccatttgcac atgttcgaaa tattaaattt ttagctaatc gagatttcta
    34741 tgaggcacca cataaatccg aatacggttc attagacatg taccgcatac taaaaacaat
    34801 gtatgacaac ggatttaacg gatacatccg tcctgatcat ggaagaatga tctggaatga
    34861 gacaggaaga ccaggatacg gcttatatga tcgagcatta ggtgctgttt atctaaatgg
    34921 attatgggaa gcaatcgaaa aaggaaacaa aagtaaagat aattagtgaa aaaaactgta
    34981 attttattat gtaaataaga aggatgttca aattcttgat acataaatcc ggaggttgtt
    35041 aataagcatt cggatttatg tatcttattt ggtctaggaa gtaacttgat tttctttttt
    35101 cgattgatcc atgagtgctt cttcttttaa ttcaaagata tattctgaga tcctcataat
    35161 cacttttttc cagtcttctg gtgtgatgat tccttttaaa atatagattt ttttgatatg
    35221 agaaggcaat tgtttcaaag ggcagtcgct gataacgatg ttgcagttct ccataaaatc
    35281 attttgtatt ttgatcgatt catttgaaaa aatttgttct atcttaacga tcagatcttt
    35341 actgatataa aaatcacgcg tatagttcac accaatcaca attcgcggct gttttttgta
    35401 gcgatcatac aaatgtacta ggtcttcaac catccattgc acattttcct tttctaaaat
    35461 aactggtaac aagtgttgat tttgttctct gaaatccata taaaattgtt caatggcggt
    35521 ttggacttct ttcaatacgc tatgttcttg ataaagcatg aaagtaggaa ggggcgtatt
    35581 tggttgattg aagttaagaa atccattata aagtttattt cgtgcgaatg ccaatgagta
    35641 aagaatcttt tctttttcag gtataaacaa atcaaataca gtacaaaggg actccaccat
    35701 ttctcttgaa taaagaacat gaggaacgtt tgcttttttt aaaagtttgt attgctccaa
    35761 gcttgtttct tccgattcga ttttcgtgat agaaagtcga gctaaaatat tcactaagat
    35821 gcgttgttcg cgacaaattg gcagattagg tcgcaaaata tctacagaga gatcaataaa
    35881 aaagtcaata tattcatact ctgtgaattc tttttgtacg tctttcacag aagttgcagg
    35941 aaaattctct ttacatattt ttaatagaaa atataattta tctatcatac cgctatttag
    36001 tcggtcaagt acttcttttt taaaaaaagt attcatcata aaagccacta cttgcggatc
    36061 ttcatcataa aattctgtag cagtacttga aaagatgttc caataaatat ctaatgctgc
    36121 atattgaatt tgtacctctt ttccagaaaa agactttctg ccattattag aaaaggagat
    36181 agacaaaccg tactatgcta aaaatgcatt aatctttttc attttcgtat acaaataaga
    36241 ggcactatag tttgtttgct gactgaaact gataatcgaa tttgtctgac agctgaacaa
    36301 agaagtcaag atctgataac tgactgattc gttgcagtat cttccaaata gacgataata
    36361 gcagtaagcc ggatcaattc cttcaaaatt caactttaaa aaaggttttt gcttatcaat
    36421 atgcagttct gttagattga gacgctcaaa gtcttgttct aattctttga tgtatagtaa
    36481 aaaatttgat tcagacatat ggaaatgatc tgctaaatat tgtgtagtaa taaagaaacg
    36541 atgttcagat aggaaaagaa aaatatctaa ttttgtattg ctttttttct tcaagataaa
    36601 cgttttaatc gcttcttgag tttgcatgaa agaggctcct ttttacttaa attgttaaaa
    36661 cttgaaaata ttactgtttt tttcataaat ttagacaaaa aaacagtaaa catataggta
    36721 gaatctctac tatcttattt cttgcataca aaaaaatcaa ggagtgagag agttatgaga
    36781 tattcaacca tcttaatatc aacatttgca gccttaagct tatcgcttac tataaatcag
    36841 acagtccaca cagaggagac agaaacagcc aaatggacag aaaccaagtg ggccaacgtc
    36901 aatcgaatta cctttcagga tgaattttca tccttcaatt caggagtcgc aaaattaaga
    36961 aaaggacaaa cagcgaccat caaagcaaaa attgactatt cgggagactt agcacctata
    37021 ctacaatcag ctgttacatt tgagaatgtt gatcccactt tgtcgattgg ctatgacgag
    37081 aacactttga ctatccaaca caagcaagcg atatttacct tcaccgttac attaaatcag
    37141 gacttgttaa aaccagcgct ttttactgtc aaggtatcag atggactacc gaacgatcat
    37201 catttaacgc cgtatagtca gcggcagaca attgagcaag attcagccat cgactcagga
    37261 ggagatcttg ttgaagaacc aacagataaa ccagaaaatg aaaataagcc agaagtaccg
    37321 cctacagaaa atccagacgg agaacagaaa ccggaaatag aacctggaga agaacccgat
    37381 acagaaactc aaccagagcc agacaataaa tcaaaacctg aaataacccc tggagaaaaa
    37441 ccagatgtaa ctccagaacc agatacggat tctggaaacc aaacagtacc ggaaacaaat
    37501 ccagacacag ataatgaaac tgaaaatcca gaaaaaccag aggtagatcc agaagaaaaa
    37561 ccagatgtga ctccagaacc agatacggac gcaagagacc aaggaatacc agaaaaaata
    37621 aacaaaaaaa caattcaaga ggatggaaaa aaagagagta aaaaatcaaa tctagcaatt
    37681 ctaaaaataa atgaagagca gctgaataaa aaatcacgaa tatttgatag cgcccaatca
    37741 gctgaaacct taaaaagtag caaggataca acctttgctg tcctgaaacg aaaaataaac
    37801 agctaccaaa atccggagag tcacaaaaca aagttatact gtggagcgga atcattctat
    37861 taagtatagc aacaatgctt tctgcaaaaa gatttaaaca aaacagatct ctctaacatt
    37921 tgaataatgt ctgtgaacgc atttttcaaa taaaaagaaa tatccagaaa atgaccccaa
    37981 aataccagat tgaaatctga tatttggggt cgttcatact ttatctttct tcatatttat
    38041 tttaagggat atctgtttct tttggaagat ggttcgggat ctttttcact ttcaatacat
    38101 ctaaaaagaa ggtaaagatc ggaatgccga caatcaagcc ccaaacgcca aagaaccgtt
    38161 cgctaacaag taagaccaca aatgtataaa aaatcggcag ttctgttttg ctggacatca
    38221 acttcggatt cagcacataa gactcaatta gatggacaat caaaatcgta atcaggatat
    38281 aaacaacatc tcggatgcct ccttgggaat aagctatgaa agatagagga atacaagaaa
    38341 tgataacacc tgctactggg atcagactta aaatgaaaat catgatcgct aaactcagca
    38401 gctgatgaaa gccaaataca gccaaggcga ttgtagtgag caacgtattt aaaagagcga
    38461 caacaaattg agcttctaat accaaaccaa atgtattgac aaacttatcg gcaaaatagt
    38521 aaatatcttg aaagaaccaa gaaaattcac tttttaaaaa caatcttgag aatacaattg
    38581 tttttttctt ttcaatcata aaaaagaaac ttaagatgaa tgacatagca aacgccactg
    38641 ccatttttcc tatatcctgt aaatagccaa gcgcaatcga agcgccattt tgaagctgtt
    38701 caaaaaaatc gtttcgctca atataagtat ggatatattg taaaacagga tctgcatctt
    38761 ttggctgatg ctcgtaaaaa ttaataacgg actggatcat gtcaaatgtt tgatgaataa
    38821 gcatcgggat atactttgtg aatgccagat agataaggta aacgatcagt gtataaatca
    38881 tgatagctaa aacacctgta gggattcgga caaatcgctg aatgatttga acaagatgaa
    38941 tcatcaaata agtaaagata aatgtgagca aaatggttgt aatcatactt ctaactaaga
    39001 aaagaacaaa aacgacaaat aataaaacag tgagacggcg tattttttca ttcgccaaaa
    39061 aacgctgata aacggtcaaa tcgacaacct ccaaataaca aaaaataaac acgttattca
    39121 ttatatgatg gaatatgaaa ataagaaaga gcaaaaagaa aaaccgctaa atgacgttat
    39181 cttatgagtt ggttttcctc ataaaatcgt tcatctagca gtttcagccc tttttctggt
    39241 cttgatgaaa attatctagc atttttcggg tcagatgttg cagtgtatcc aattcttcct
    39301 gttcaagtgg aagataagac ttgatctttt gtggaatacc ttctgcttgt ttttgcaacg
    39361 cagcaccttg agcagtcagc gtaacattta cgattctttc atcacccgtt tcacgctgac
    39421 gattaatata atttttttct gctaactttt ttagtaaggg agtcagcgta ccagaatcca
    39481 gacacaaatc atttcctagc tctttcactg aagtcttttt cttttcccat aaaactaaca
    39541 tcacaagata ctgggtatag gtaagattca gcggcttgag gaggggagtg tagtgtctaa
    39601 tgatttcttt agaggcggca tataaaggaa aacatacttg attaactaaa tatagatctt
    39661 ccatttttcc acctccgctg ttttactata gtgtatcata gcggatttac acaaaaaagt
    39721 ctattcacta actgctttca gagtaacttc tatatttcca gctgtagctt ttgaatacgg
    39781 acacacttta tgcgctgcct ctaataattc ttgcgtttct tccagagaaa gaccttcgat
    39841 agatccttca atctctacac ctaagacaaa gctcgtttca ctttctgaat aaagggaaac
    39901 ttgtgcactg acagtagaag ccccagagat atttttttgc tgtttgatca attctaatgc
    39961 actgttaaaa catgcactga aaccagctgc aaacaattgt tcagggttgg ttgcattttc
    40021 gacgcgttta ccaggagctg caatattcaa ttcgaatgta cgatcgggat tatgcacttc
    40081 tccagagcgt ccgcctgtgt tgatcatttt cgtagaatac atttttttca taaaattacc
    40141 acctttaatt atattttata caattgaatt ttacacaata taattgtgga aagcaaagaa
    40201 atggattggc ataagataaa taagagaaag cacatgaaac agacgcgctt tctcgaatag
    40261 caaacatata caaaaaatat cagagacaaa aaataatctc atcataaaca ttacatatat
    40321 ttctcaaaaa gttgttttct ttcttcaaaa attacttcac gatggacctg atgaagcatc
    40381 cataaataac caaaaggatc tctgaacatt gagttagtca caccaaagtc catcatttct
    40441 gtcatttctt gaatctctac acagccattt cgtaatgctt tattatgtgt gtcctcgata
    40501 tcagagacga tgatattgaa ccagatcgta tttggatgtt cagcagtagg agcagtcaaa
    40561 ccaagagacg tgttttcatc cagcatatgg aatctcgtac catacaaggt aaaaatgact
    40621 tcattattgc ctctagggta atctgttgcc tcaatcagtt gtatttcatc aaagattgtt
    40681 tgatacagtt ctagtgcttt caaactatca tttaatacaa aatcgatttc cgttccttta
    40741 tgcataaaga tctcctctcc ttttcagtcg aacagttact agattctttt attataccag
    40801 ctaaagaaaa cgcattcaaa aaaatagcgg atttacttac caactcattc gattggatga
    40861 taagtaaatc cgcgtcccat tacttctgct acgctgctga caatgacaaa ggcacttgga
    40921 tcgatttctt ctatcaatgg tttcattcgg gaaaattcat gatcagtcac aacgatcaat
    40981 aaaacctctt ttgactttcg attatacccg ccttttgcct ctagcagggt aaggccacgt
    41041 ccaatctcag cacttaagcg aaggcggatg tcttccaaat aatgttcact catgaccata
    41101 acagatttct ttcgattgat acctgtttcg atataagtca tgacaattga agtgattgca
    41161 atagataaaa tagcataaag aaactcttct attccaaaaa taaacagatt aagagaaaca
    41221 acgaatgcgt ctgtaaaaaa taagccaatc gaagtattca agtggaaata ttttttaaaa
    41281 atgaggggag ggatcgtcgt accgccgcta gaagagttgt ttttatataa aatcgcaact
    41341 cctaaagcaa aaatcgcact tccaaaaatg acagacaaca accgatctga agtaatcatt
    41401 gtttctggaa ctattgcaat gattaaagga aaaaccaagc ttccgaaaag tactttaaaa
    41461 aagggttttt tacctaaaaa tagaagagct agtaccaaca taacgatatt caacactaaa
    41521 ataactatag ctcggtcaaa gcctaaagca gcttccagta atattcctag accgctgaca
    41581 cctccagcag caatatgatg aggccctaaa aacatattga tagcgactcc taatatgaag
    41641 agggcaaaaa taatcttaat gtatgtccat ataaattgtc tcgtttcttt catttattca
    41701 cttccttaat tcattaataa tactcttatc ttattataac ttacttttca ccttaagtta
    41761 actttaatta ataaaaaaat taggctagtc taaattatta tgtttcattc ttctagaata
    41821 tacttctacg ccaaaaactg ttaaaaaact tttactttag aaaattggag aaattgatcg
    41881 cttaagataa attcaggaca ctaaatagta caggaagtag actaaaactt ttaaaagttt
    41941 taagtctatc tatttggcaa gtttaaaaaa taaaaattcg gtatcaaaaa actgttaccg
    42001 ataacatttt tgaaagcgtt gtcttttgct tctctatcac ttatagtgat gacgtcatat
    42061 taaaacacaa ggaggaaatc aatggataca gctgcaattt atcatcgacc ggaaagtgaa
    42121 tatgcatttc tatatacgaa tacaagattt cgtattcggc ttcgtactag gaaaaatgat
    42181 atcaaaaaag tatatgtgct atgtggagat ccatatacca taacaactga aaaatggtat
    42241 caaaaacaac gaccaatgaa aaaatgtcta agtaccaatg ttcatgatta ttgggaaatt
    42301 gaagtgacga gcgaaacaag tcgcttacag tatgcgttcc atgttgttgg ggaagataac
    42361 acggactgtt tttacggtga tcaaggaatt tttccttatc gagaaaatgt gattactgaa
    42421 ccaaattttt attttcgaat accttatttt catcaaatcg atcgattcac tattccagaa
    42481 tgggtaaaag aaacagtatg gtatcaaatt tttcccgaaa gatttgcaaa cggggacaaa
    42541 gcaaatgacc ccgaacacac tttaccttgg ggaagtaaag atccagaccg agaagacttt
    42601 ttcgggggag atttgcaagg tgtgatggat catttggatt acttgacgga ccttggcatc
    42661 aatggcatct atttttgtcc catatttaaa gccacatcca atcataaata cgatacgatt
    42721 gattattatg aggtggatcc cgcttttggc gataaaaaac ttttaaaaaa cttgattgat
    42781 gaagcacata aaagagggat acgtatcatg ttcgatgctg tattcaatca tatgggtgtc
    42841 cattcaccac agtggcaaga cgttctcaaa aacggagaaa aatcgatcta taaagactgg
    42901 ttccacatcc gttttttccc agtagattct tatcagatga ctgacttacc agaaactgct
    42961 gaaaatatcc catatgatac ttttgctttt actccattca tgccgaaact aaatacagca
    43021 aatccagaag tgcaaaaata tttgctggat atcgcaactt attggataaa agaattcgat
    43081 attgatggat ggcgtcttga tgttgctaat gaagtcgatc atcatttttg gaaaaaattc
    43141 agagaagcag ttacagaaat caaaccagac atctatatcc ttggagagat ttggcattcc
    43201 tctcaagctt ggctgcaagg ggatgaattc catgcagtga tgaattatgc atttacagat
    43261 tcgattaaag attattttgc aaaaaagaaa atcacagctt cacaaatggt cagtggaatg
    43321 aatcatcagc aaatgcttta cagagatcag gtgaacgaag gaacattcaa cttattagat
    43381 tctcatgata ctgccaggat cttgaccctt tgccaaggta acaaagaatt gatgaagtct
    43441 gtgatggcct ttatgtttct tcaaaaaggg tctccttgta tctattacgg gacagaaata
    43501 gggatgactg gtgaagatga cccggattgc cgcaaatgta tgatatggga gaaggaggaa
    43561 caagatctag agctattcgg ttttataaaa gaacttgttt ctctaaggaa acagttgtct
    43621 aagattattt ctgaaggttc tactcagtgg ctaatagtaa atgatcgtga agataagctc
    43681 tatttcacac ggaaactaga gggacagatc atctatgttt actttaatca gtcaaaagaa
    43741 ccttgggtag tagaacagga aaatgaggtg attcttagtc aaaattgtca gttgttagaa
    43801 gacgggaaag cagagatacg acaatacgga tttttgatca tgtgttgaaa actgttaccg
    43861 gtaacaacaa gaaagcgttt gcaaatgaag atttgtgccc attataataa gggtgtaaca
    43921 gcacgttgaa tacaaaggag gaaatgaaga tgaaaaaaag aagtgtgaaa cagttgggtt
    43981 tagggttaat ctctttagga atcttaggcg gattagcggc ttgtggcaat ggtaactctt
    44041 cagcagaagg ggaagccgat gaaggaaaaa cgttaacagt ttccgttgat tctggatata
    44101 aagattatat aaacgaaata aaaaacactt tcgaaaaaga aaacgatgtg aaaatcaagc
    44161 tagtagaaaa ggacatgttc gatcagttgg aatcattagc gttagatggg cctgctggaa
    44221 agggacctga cgttatgatg gcagcatatg accggatcgg tgcgttagga cagcaaggac
    44281 atctggcgga agtaaaactg ggaaatgaag cagcttacga tgaaacagac aaagcccaag
    44341 tgacttatga tggaaaaatc tacggagaac ctgcagtaat cgagaccctt gttttgtact
    44401 ataacaaaga tttagtcgat acagcaccat caacgtttaa agatttggag aatctatcca
    44461 aagacagtcg ttttgctttt gagtcagaag caggaaaaaa tacaggattt ttagctaaat
    44521 ggactgactt ttattattcc tatggtttaa ttgcaggtta cggtggctat gtatttggtg
    44581 atgatggcac aaatccttca gatatcggtt tgaataatgc aggtgctgta gaaggaatct
    44641 cttatgcaac agattggttc aaaaatgttt ggccaaaggg aatgcaagac ataaaaagtg
    44701 caggagactt cgccagccag caattcatgt ccaataaaac tgcagcaatc attgacggtc
    44761 catggcaagc gcaaacatac aaagaaaaca atatcaatta tggtgtagcc aaaattccta
    44821 ctctaaataa tggacagcct tatcaaccgt ttggcggagg aaaaggatgg gtagtcagca
    44881 attatgctaa aaacaaagac ctctctcaaa aatggcttga ttatgtaacg aatcaggaaa
    44941 atcaagaaaa attctttgaa atggtaaatg aaatccctgc aaaccaacaa gctagggaaa
    45001 cagcaaaggc taaaaacgat gaattaacaa cagctgtgat tgaacaatat gaaacagctc
    45061 aagcgatgcc aaacatccca gaaatgggcg aagtttggac aggtgcagaa aacttgatgt
    45121 tcgatgcagc atcaggttca aaaacaccaa aagaatccgc agatgaagca gtaaaaacaa
    45181 tcagtgaagc catagaacaa aaatactgat taaaatgata accgtccatt tttataaaaa
    45241 atggaacagg tgcttcagat aaaagtggca agagcgagat ggaaaattat cttgctcttg
    45301 ttgccattat cttaaaagca gtttgcggtt tagcaagttt agagggggca ttcagatgca
    45361 gcaagataaa acaagcaata tcaacgaaaa aaaaatcacg ctttgttcac ttattccagg
    45421 gatggggcag tttgtaaatg gccaagcttt taaaggtatc gtttttttcg ccatattcgt
    45481 cctattcatt ggtcagatgc ttctgggcgg atttcatgca ttggtaggat tggttacttt
    45541 gggaagtata ccaatggaag atcattcatt atttattttg attgaaggca ctttgcaatt
    45601 catcattaca atcattttct tgatttttta cggtttgaat cttttagacg cttatcgagt
    45661 agcgaagatg cgtcaagagg gcaaaaaaat caatcggacg atgaaggaag tcatacataa
    45721 tataggtgat gaaggttttc cttatctatt gacacttccc gcttatcttc tcatgatttt
    45781 tacgatcatt ttcccagtcc tagttacatt gttcactgca tttactaatt atgacttcaa
    45841 tcatattcca ccagccagtt taattgattg ggtaggggct aaaaactttt ttagtatctt
    45901 ctttttaagc tcatatcgta atactttttt tgcagtcttt tcgtggaccg tgatttggac
    45961 tttatgtgca acaactttgc aaatcaccct tggtattctc acagcggttg ttgctcacca
    46021 gaaatttatt aaattcaaac gtattttcgg tatcattttc ttattaccat gggcggtccc
    46081 agcttttatt actatcatga gtttttcgaa tatattcaac gatagcgtag gtgccatcaa
    46141 tactcaagtg attcctttca taaaccagct tccttttgta gatatcagtg caatctcttg
    46201 gaaaacggac ccgaactgga cgaaagtagc aattatctta gtgcagggct ggttaggatt
    46261 tccctatatc tatgtgatgg ttacaggaat cttacaatcg atttcagaag acttatatga
    46321 agcagcaaaa atcgacggag caaatgcatg gcagcgcttt tcaaacatca cgcttcctgc
    46381 tgtcttccta gtggcagcgc caacatttat tacacagtat acggggaatt tcaataattt
    46441 ctccatgatc tatctgttta acaatggcgg tcccggaagc gtaggcggag gagctggttc
    46501 tactgatatt cttatttcct ggatctataa acttacgact ggaacttctc cgcagtattc
    46561 tatggcttca gcaatcacgt tgattatctc cgtcatcgtt atctgtgtgt cattgctggt
    46621 atttaaaaag acaaatgcgt tcaatatggg ggattaacaa tgaaaaaatt tcattcgagt
    46681 gctcgattcc aaaaacgact ttctcacttt tttacttact tttttctttt aatactgtca
    46741 gtcattatca tctatccgct tttgatcaca gcaagtactg ccttcaagtc aggaaatatt
    46801 gcagctttta gtttagatct ttcaagtgac tggactttag gaaactttac tcggctattc
    46861 agtgaaacac tttacgggac ttggtataaa aatacattga tcatttctgt cctaacaatg
    46921 atcgtacaag tgactgtagt aactttggcg ggctatactt atagtcgcta tcgttttatc
    46981 ggccgcaaat caagtttgat gttcttttta gtgattcaga tggtaccgac tatggcagca
    47041 ttgactgcct tttatgtcat ggctttctta ttagaagcgc tcgataagta ctggttcttg
    47101 acaatgatct atataggcgg tggaattcca atgaatactt ggctgatgaa aggatacttt
    47161 gacactgtac caatagattt agatgaatct gctaaacttg atggggcagg gcatttcagg
    47221 atttttttcc agattgtatt accgcttgtc aaaccgatgc tcgccgttca agcattatgg
    47281 gcttttatgg gaccttttgg ggatttcatg ttagctaagt tcctgcttcg aacacctgaa
    47341 aatcagactg ttgctgtcgg cttacaaaca tttatttctg atgtgacaaa ccaaagagtc
    47401 tctctttttg ctgctggggc aattttgatt gcactaccga tttgtctatt attcttcttt
    47461 ttacaaaaga actttgttac cggcctgaca tctggcggaa caaaaggata ggagcagagt
    47521 atcatgcaaa catttccgtt aaactatttt tccgcattac gtacgccaac tcaagtgttt
    47581 gcgggacgca aactattatc atggcctaaa tttttcttga tatttgtatt tttagtttcc
    47641 ttgatggtca tgcctgtgac tcttttttat gccaatcaga tccaagcgat tccattagaa
    47701 caatttctat ccgttcattc gctgatcgat gaacaaggaa cccaaaaatt ttctgaactt
    47761 aaattatctg aaactgggtt acaagcatcg caacaaacga tagctgtgac ccctgaaatt
    47821 ttggtaggtg tgtctttatc tgagaaacaa caatccgatc atggaacttt tattgatttt
    47881 gagaaggaac aatgggtgat ccaacaaaag gataaatctg gtatacgccg ctatacgatg
    47941 aattatagcc catctttcca accagattct gtacgtacgc ccgaagattt ccaacgattt
    48001 ttagaaagag aattttatgc cagtaatcgt ccaacaatca ttttatctta tagtttaagt
    48061 cttggtcttg tcctatttgt catgacgagt ctcattttat tcggggcttc ctttttcttg
    48121 tggatgacaa gaaaaagcca actttcatcc attcatacat tcaaagagag tgcaaatttg
    48181 atgctgaatg ttatgggaat aggttccatg gcagcagcag ttgtagggtt tatccacttt
    48241 gactttatct tgatgctaag tgtccaaaca acgataactg tcttgctgct tttatgggtt
    48301 tttgtcaaaa caagattcaa agataagcgt gtcgaatgac aagtttaagc gatttatgcg
    48361 acaatgaatg tgaaaaaaat gaaaaataaa gtagtttttg aaaaatttct gaaaaaatta
    48421 aacttcttag ttgattcttt tcttttttag tattaacgta atagggtagt ttttttaagg
    48481 aggaaaatca tgttagagaa aactttatac aatcaattat tttcacgttc tttctcgctc
    48541 cctgtcgaag taaattattg ggacggtaca acgaaacaat acggagatac ggacactcct
    48601 acccaaatca aaatcaatat ccatgaagaa atcccaatga aagagattac aagtaacgca
    48661 tctttggcac taggagaagc ctatatggat catcgaatcg agatcgaggg aagtatccaa
    48721 gcattgatca acgatgctta tcagcaagca aacagctttt tacgaggaaa agattatcta
    48781 aaatggctgc caaagaaaga aaaacatacg aaacaaaaaa acaaagaaga tatccatgcg
    48841 cattatgact taggtaacga cttttataaa ctttggctag atccaacttt gacttattct
    48901 tgtgcttatt tcaatacacc tgaagatacg ttggaacaag cacaaatcaa taaagtccat
    48961 catatcttag acaaactctt tatcaaagaa ggcgaaacgt tgcttgatat cggttgtggc
    49021 tggggaacat tgatgttcac tgctaccaaa gagtataatg tcaaggcaac tgggatcaca
    49081 ctaagtgaag aacaatacga tttgattacc aaaagaataa aagaagaaca tttagaagat
    49141 aaatgccgtg tattattaat ggattaccgc gaactaaaag gcgaaacgtt tgatcatatc
    49201 acaagtgtag gtatgttcga acatgtaggt tctgaaaatc ttgaaggtta tttcaaagtg
    49261 gtaaaagatt tattgaaacc aaaaggaaca gctttgatcc atggaatcag ccgacaacaa
    49321 ggcggtgcga caaatgcttg gatcaataaa tatattttcc ctggcggtta tgtccctggt
    49381 gttactgaat tagttgataa tattacaaaa aacgatttgc aactgattga tttggaaagc
    49441 ttacgtcgtg actaccaatt gacattagaa cattggacaa agaattttca tcaagtccaa
    49501 gatcaagtca cgaaagaaat gggtgattcc ttctatcgaa tgtgggatct atatttacaa
    49561 gcttgtgcag cttcatttga atcaagtaat atcgatgtga ttcaatattt gcttgttcaa
    49621 cctggaaaca atgacatccc aatgcatcgt gcataattga ggcaaaagta ctgtttaaag
    49681 actatttaaa aagaagctaa gttttatgat gctccagaag tgaacttttt tgtctaactt
    49741 ctaggattgt ctctaaagct tagtttcttt ttctttatat tttcataata aaagtttggt
    49801 tctttaattt ttaaacatga cagaaaattt tttcttcgtt atacttgtaa tagaatacta
    49861 ttttataaca aaggggatcg aatcaatgaa aaaaactgtt atttatacta gtttatttgc
    49921 agctttgttt ttagctgctt gtcaatcaaa taccaatcaa ggcacatctg ggaatacgtc
    49981 ttccagtagc gaacagcgct cttcacaggt atcggactcc tcaacaaaag caagcacatc
    50041 ttcgtctagc cagacaaaaa gttctagtga agcaagtact cagtcagata tcaaagtgtc
    50101 tgcagctcgt gcgatcgaat tgttccaaga taaataccca gatactgcaa ttactagttt
    50161 ggaattagat agtgattggg gatcttactt ctacaagata gaaggtgtcg atgatcaaaa
    50221 agaatacgaa gcaagaattg atgctcaaaa tgaaaaaatg gagacagaga atccagaaac
    50281 tctagatcga gatgaacaaa atggtcaaaa gaaaaaagaa gatggtctgg atgttgataa
    50341 attgatcacg attgaggaag cagcaaaaat cgccgtcgac aaagtaggaa gcggtacggc
    50401 aacagattgg gatttggata aagatttagg tactacttat tgggaagtca aagtaaaaga
    50461 cggcaatcaa agtacatcag tcaagatcaa tagccaaaca ggcgaagtac tgtcaactga
    50521 acaagatgat taagaatttc ttcggaaaac aagagttgat ttttctttta gtcatgatac
    50581 actagacaaa ataacttgtt tgaaggagcg atttacttga gtttagaaac gacctttgcc
    50641 aatcatatct ttgccaatcc tttgatgaat gcatctggtg tccactgcat gactacccag
    50701 gaattagatg aactggctca ttcagaagca ggagcattta tcactaagag ctgtacgatc
    50761 aatgaacgaa aaggaaatcc cgaaccacgc tattttgatg ttcctttagg gagtatcaat
    50821 tctatgggac ttccaaactt aggtttttct tattatctag agtatgctct tgcgtatgaa
    50881 aaagtgcagg aaaaccaaaa tcaaccgtta tttttttcca ttgccgggat gagtgtccag
    50941 gaaaacttgg aaatgcttga gaaaatagaa aaaagtgggt ttaatgggat cactgaatta
    51001 aatttatctt gtcccaatgt gcctggaaaa ccacaactag cttacgattt tgaggccact
    51061 tatgaaacac tgaaagaagt attcagcatc ttttctaagc cgctaggaat caaattgcct
    51121 ccttattttg attttgctca ttttgatcag atggctgata tcttgaatca gtttccattg
    51181 acctatgtca atgctatcaa cagtgtgggc aatggtttgt atatcgatac agaacaagaa
    51241 gcagtagtca tcaaaccaaa agaagggttc ggcggcattg gcggagagta tatcaagccg
    51301 actgctttgg cgaatgttcg cgctttttat acacgtttga aaccagaaat ccaaatcatt
    51361 ggtacaggtg ggattcggac aggacaagat gcatttgaac atctgctatg tggcgcaagc
    51421 atgttacaga ttggtaccga gcttcataaa gaagggccgg aaattttttc tagaatcata
    51481 aaagaattaa cgcagattat gtcagaaaaa ggatatacgt caattgacga atttaaaggc
    51541 aaattacgca ccatttcata gcaaagagac gaaggtcatg attgatcttc gtcttttttt
    51601 ataaaaaaca ctcgtctgtt cattcctgtg caagcgtact cattgtatgt tagacgaact
    51661 tgtgggaaaa taacagaggc aaaaaggagg ataatatgaa tgatgcaaca gaattagcaa
    51721 aagagcttaa agaaaaagaa tttagttttc aagaactagt tacggatata cagaaaaaaa
    51781 taaagaagca aaatcatgaa ttgaatgcgt ttgtcgcgct tgaaccattc gagagtaatt
    51841 cccacgagct attgattccc cagtcagaaa aagggccatt ggctggtatc ccatttcctt
    51901 taaaaatgct cggtcaagaa aaaaagggat ggctagctac ttcaggatct cgtttatttg
    51961 aaacacaccg agcttctcat acatctaatt atgtgcggca agcagaagcg ataggtctag
    52021 ttccttttgg acaaaccaat gcgccagagt ttggtttcaa aaatattaca gacccagtca
    52081 tctatggccc agcaagaaac ccttggaacc ttgaatgtac accgggcgga tcaagtggag
    52141 gagctgctgc tgcagtttca tcaggaatcg ttcctttagc tggtgctagt gatggcggtg
    52201 gttctattag aatacccgct tcgttttgcg gattgattgg gctgaaacct tcgcgaggga
    52261 cgatgccagt tggtccatat gcttggagag gatggcaagg agctgctatt gatttcggct
    52321 tgacagtttc tatgagagac acggaggctt tattttatgg gatgagaagt atccattccg
    52381 gtgcgccata tcaagtatcg ccagttgagt ggcaaacaca tccaagaaaa aaacggttga
    52441 agatagcttt ttgtgttgat tcaccgatcc actcacagat tagtgaagag gcagtacttg
    52501 ctgtaaaaaa agctgtagat ttccttggaa aagaagggca tgatttgaca gagattcctt
    52561 acccactaga tggtcgtaaa ctgatcacgt cttattatca gatgaatggc gcagaaacag
    52621 cagcaatgat ccgctcgatt gaaacaggca tccagcgagc tgtcagaaaa gaagaacttg
    52681 aacccatttc ttggactttg ttccaatatg gtcagaagct ctctgccgct acttacatcg
    52741 attctctgca tgtatgggat gaagcagcaa ttgtcatgga aaacctacat caagaatacg
    52801 atctattcct ttcaccaacg actgcattta ccgcccctaa aatcagcgaa gatttgcaaa
    52861 gtgatgcgat aagagcacag atggaacaca tcagtgattg ttctgaagta gaaggtttag
    52921 acgttgtttc ttccatgttt gaggagagct tgaagatcac accttataca cagttggcta
    52981 atctgactgg acaaccagca atcagcttgc ctactcattt gacaaaagaa aacatgcctc
    53041 taggaatcca atttatggct gccagaggaa gagaagattt gctatttcaa atcggctatc
    53101 tatttgaagc aaatcatcag ttccatttac caaatccatg gaaatagcag aaacaaggag
    53161 aagaagaatg aagaaaaaaa gattgtttgc tctaataact agtgcctttt ttattttaag
    53221 cgcttgcggt acagctgccg ctaatcagga agataacagc tggagtaatg tagaaaaaaa
    53281 gaaagaatta gtagtagcga cttctggcac actgtttccc gcatcttatt ataatgatca
    53341 aaatgaatta gttggttatg atgtagattt ggcaaaagag gtggctaaac ggttaaatgt
    53401 caaaatctcc tttaaagaat acaacgtgga tggacaaatc acttctgttt caaaaagaga
    53461 atcagatttt gctgcgaacg attttggtat cacaaaagaa agagaaaaaa aattctccct
    53521 ttcagagact ttcaaatatt catttgacag tatgatcgta cgaaaaaaag atgattcagg
    53581 aatccactca cttgaagatc ttaaagggaa aaaagcagct ggcgaaccca atactagcta
    53641 tatgcgttta gcggaaaaac acggagctaa attagtcaca tatgacaatg ccacgaatga
    53701 tcagtattta agcgatgtag caaatggtcg aacagatgtt attctaaatg attattatct
    53761 gcagaaaatg gccgtatctg ctttaccaga tatccctgta aaaatactgg agaacgttta
    53821 tttcaatgaa aacgaaagtg gttttttatt gaaagaagga aatgatgctc tgaaaaagaa
    53881 aatcgatggc gtattaaaag agatgaaaga agatgggacg acaaagaaaa tatctgaaaa
    53941 atattttcaa actgatgttt cagtcaaacc gaaagaaacg atggctgagt cggtgagtga
    54001 gtgatgtact ttcctctaat tgatttttcc ctcatgtgga cttcacttcc tttcgtactg
    54061 caaggcttgg tatacacatt agggattggc ttcgtgtcgt ttcttttagg aaatctggta
    54121 gggttgcttt tgacagtttt aggtcttttg gattggctgc ctctgaatgt atttattcgt
    54181 ttttatttat cgttctttag aggcattccc gcactagtcc tgctgtttct gttatatttt
    54241 gggttacctt atcaattaag tgccttaacg gcttcagtca tctgctttac gattaccagc
    54301 agtgcattta ttggtgaaat ctatcgagga tcactagcag gcgtttcttc aggtcagtgg
    54361 gacgctggtt tagcttctgg tttttctttc tttggggtat tgaaatatat cgttttgccg
    54421 caagcttttc gaatctcagt accggcactc agtaacgtag ctatggatct agtgaaaggt
    54481 acttcgttag cagcaacaat cacagtgcca gaaatatttc aaaaagcaaa gatcataggc
    54541 ggtcggacat tcgattattt ttctctctat attttagttg cactgattta ttgggtcatt
    54601 tgtatcggga tcgaaaaagt gcaacagtat ttagaaaaac gttctatgca tcagtcaatc
    54661 tgaaaaatag aaatggtgct agcgtggctg gcaccatttc tattttttgt ttcttgtata
    54721 ttctgcctag tattttaaaa ccatttcatg taaaatgtaa atcgaaaata tgttcggagg
    54781 tagaaaacat gaagaccccg ctaaccatcg aaatagaatc ctcgttatac caatattgca
    54841 tcgagcaagg cggcttggtt gtagaagaag tcacgatgcc tgatgaccaa ggaattgtag
    54901 atacgcttag ctgcttgaca aaatttgatg gaagccgaga atggcgatgc tatgagctga
    54961 aagtgacaaa agcagatttt cgctctacag ccaaactgtc atttgttgga cattataatt
    55021 attttgtttt accaagtaaa ctatatgaag aagtaaaaac tgaaatccct acaggaatag
    55081 gtgttttagt gtatcgtccg tacacggttg aagaggagat gcctgcctct ggtacatttc
    55141 tgattgcgaa aaaagcagca aagaaagagc ttgctgtacc ggaagaagct ttgacaaacc
    55201 gcttcatggc ttctttattc agggaagtaa gaaaagcaaa gcaaatggag cgaggcgtaa
    55261 aatattttcc aacagatcaa ttgtacaaag aattgaaaag acgttcagaa aatcaagatc
    55321 cattttctaa cgaacgatat tatgaacggt ttttagagga aatagctagt caggcaatca
    55381 atgagttgca agaagaagtt atcgcgcttc agcatgatta tgaatatttg aggcaacaac
    55441 agcagatccg tcggttgcct acagagccat tggagtgaaa aatatgtact atccttattt
    55501 aagaggaaaa caatttgacc tattagcatt aaaagaagca ctgtcgcgag gattgctctc
    55561 caataaaatc caaccagtga tcgaaccagt acgtgattcc gctacgctta aaaatgtgat
    55621 cgaattattt caaaaaaagc accatcgaat cgctgtgatc caaaatcccc aagtaggaca
    55681 attcaaatta ttcgatcagc atgtgcacag ttggacagtc aaagaaaata gctctgtcgt
    55741 ccctgcacag atcttaacgc cagaaaatct cagtgaagta ctggattcac ctccagcgtt
    55801 tcttgttttc gatggacagc actacccaaa agatacagag gtgtggaaac agttggcagg
    55861 agttgattcg aaatttttga taccagatac tagtcgcttt cgcatctggc tgcccgaaaa
    55921 caaaattgtg atccgtgact cttttcaaac gagaaagcat gttgaaagtt atgcagataa
    55981 aacagatgac ttttttagtg atgactatct ttttttccac gcagacggat atattggatt
    56041 ttctgatttc acgatcgaag gtagccgtta tttcgataaa gggttcccta gccgagcgct
    56101 tgctatccat ctaacgtata ttgatgctta cggcaatata cgcgtgaaac attttgtctc
    56161 tgacagtaac gactctgcta aagaccaagc attgaagttt cttgaagcag gagataaaat
    56221 gaaaaaatgg atcatgcgtc accatcatca actcttgatt acttcaggaa tgattgaatt
    56281 attggctctt taccagcaac aaaaattccc tggactggga gtgttgaaaa agtggtcact
    56341 tatgcatcat ttggaactta ttagtcacct gctagatcat ccaaaagatt ggcttaaata
    56401 ttattcaaaa gttcaggaac tatatgaagt gatccaatga ttagataatg taaatgaaaa
    56461 aggaatagaa aagaggaaac tggatgtata ttcggcaaac aaggaaagaa gaagtagaag
    56521 aagtggtaga aatcattaat gccgcagcgg atttcattgc ttcgcaaggc tctcctcaat
    56581 ggcaaaacgg gcagaaacca acaaaagaaa cgattttgaa cgatattgaa agaaaagaaa
    56641 gctatgtatt aatagtggaa gatcaaattg ctggaacagc tgcattagtc tcaagcgtgg
    56701 atcccgttta cacaaaaata gatggtagtt ggaaagaatc aactggtcct tatttatcga
    56761 ttcatcgtgt cgctttagca gaaagtactc gaggaaaaaa actagcaaaa ccgttcttag
    56821 aacatttgtt gacgattgca gccagcaaaa atatccaaga tatccgtatc gatacttatc
    56881 cagctaatga accgatggaa aagaccatct attctgctgg attcacttat caagggatga
    56941 ttgaatttcc ttttgaacac ggcgaaagaa aagcatatca aataatcatc aattgactat
    57001 aaaatcatct gagcaaagat aaagacatta acactactga aaaaaacaat catatgatag
    57061 ccaagaggtt gtaacagaag tggccagctt caaaaaacaa gaaagaattt ccgaaaatgc
    57121 ttctcaaatt tttgtggaat tttagcgtat tttacgaaat agctgctttc tgaaactccc
    57181 ttcatcgaga ggtcgtgaca tagcttttgt cacgacctct cggcttatcc tacgagtatt
    57241 attcgataca tttatatcaa taatcctttt tttattttat ctgcagcttc ttggaacgct
    57301 ccatcgtttg acacgactaa aagtgagggg atagctttca aacgtttcaa ctgtgctaaa
    57361 tcttctacat aaaccgccag tctggctgaa atctgttcag atgaatctcc acgttttttc
    57421 aggcgcgatt gcaatgtttc tttagagatc gtaataaaga taggacggac taccgtcccg
    57481 aaatactcat ataaatgcca aaaaccattt gctgtcaaaa cggcgtaaca atttcctact
    57541 gtcagtttct ttttaatttc tgctttactg gaaccatatt tatgttgagc atattggtcc
    57601 cactctgcaa actcatttcc cttgatcatc tgattgaatg tattgtcaga aacaaaataa
    57661 taatcctctt gatctttttc cccaggtctt ggtgatcgat tcgtgtaagt aatgatcttt
    57721 tgttccggct gaaaaatagc ttctgcgagt gaagtttttc cagaaccaga aggaccgata
    57781 aatacatagc aataattcat tgtcatttct cctttgatga ttgaacaagt gaaaaagctt
    57841 tggaaaatat ttccaaagct tttaaaagta actttgcttt tttgtatatt ataccagcaa
    57901 gccagtcaca atagcactta aaaagctgac taaagtcgct gttagcaaaa ttttcaatcc
    57961 gtgttttgcg acaagatttc ctttttcttc atttaatccc ttcatcgcac cagaaatgat
    58021 cccgatagaa gagaagttgg caaatgaaac gaggaagaca gatataattg ctgttgtacg
    58081 ctcagtaaaa tggaaattac catttgctaa ttctgtcata gcaacaaatt catttgtaac
    58141 cagtttagtc gccatgatac taccggcatc cactgcttct ttccatggga ttccgctgat
    58201 gaaggcaaga ggggcaaaga tgtaacctag gatctcttgg aaagtgatgc cgaatatccc
    58261 gtggaagata gcattgatca tggcaatcaa agcaacaaaa ccgataagca tagcagcaac
    58321 cgtgatcgcc acatggaaac catcaagaat gtattctccc aacatttgga aaaatgtctg
    58381 ttctttgttt tcttcaatga tcagctcatc ttctttttct tctaatacat agggatttac
    58441 aattgaagcc agaatataac cgccaaataa gttcaaaaca agggcagtga tcacatattt
    58501 agaatcgatc agtgccatat aagatccgac gatcgacata gaaactgtag acatagccga
    58561 tacactcatg gtgaacaaac gtttctcaga taggaagggt aattcctttt ttatggaaat
    58621 aaaaacttcc gattgtccta aaatagcaga agctactcca ttataagatt ccaatttgcc
    58681 catcccgttg attttactta atcctagacc aacagctttc ataaataatg gaagaatctt
    58741 gatatagcgt agaataccga taatagcaga aataaataca attggcatca atacggaaag
    58801 aaagaaaggt gcacttcctt tatttgctac accggcaaaa acaaagtcaa caccttgccc
    58861 agcaaaagca agaagatgat caaacatttt tgccaataca gaaacaaccg ctgtaccaaa
    58921 agttgtacgt aataatacga aaccaagaac aagctgtaaa acgaacatca caattagtgg
    58981 tttcaatttg attgcttttt tgttactgct gatcaaaaaa gcaagcccta atgtgacaaa
    59041 taaaccaata atacctaata aataactcaa ataatcactc ctattccaaa ttccgtttta
    59101 ttttacctgt tttgcaaata aaatactaat ctttagtgaa attttcatta cttttttaga
    59161 gtgaaacgca ttcattttc
//
LOCUS       DAFEKH010000192        20862 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.guided.049, whole genome shotgun sequence.
ACCESSION   DAFEKH010000192
VERSION     DAFEKH010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20862
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.guided.049"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            267..1304
                     /locus_tag="LP386_003099"
     CDS             267..1304
                     /locus_tag="LP386_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HBL1920238.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(1393..1716)
                     /locus_tag="LP386_003100"
     CDS             complement(1393..1716)
                     /locus_tag="LP386_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBL1920239.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(1703..2410)
                     /locus_tag="LP386_003101"
     CDS             complement(1703..2410)
                     /locus_tag="LP386_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBL1920240.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            2496..2837
                     /locus_tag="LP386_003102"
     CDS             2496..2837
                     /locus_tag="LP386_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HBL1920241.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SMEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAAEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            complement(3008..3856)
                     /locus_tag="LP386_003103"
     CDS             complement(3008..3856)
                     /locus_tag="LP386_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920242.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
     gene            4454..5317
                     /locus_tag="LP386_003104"
     CDS             4454..5317
                     /locus_tag="LP386_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBL1920243.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            5417..5899
                     /locus_tag="LP386_003105"
     CDS             5417..5899
                     /locus_tag="LP386_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBL1920244.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(6162..6629)
                     /locus_tag="LP386_003106"
     CDS             complement(6162..6629)
                     /locus_tag="LP386_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBL1920245.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            6752..7603
                     /locus_tag="LP386_003107"
     CDS             6752..7603
                     /locus_tag="LP386_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL1920246.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            complement(7854..9812)
                     /locus_tag="LP386_003108"
     CDS             complement(7854..9812)
                     /locus_tag="LP386_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL1920247.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(9809..10681)
                     /locus_tag="LP386_003109"
     CDS             complement(9809..10681)
                     /locus_tag="LP386_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL1920248.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(11023..11895)
                     /locus_tag="LP386_003110"
     CDS             complement(11023..11895)
                     /locus_tag="LP386_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL1920249.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            12023..12592
                     /locus_tag="LP386_003111"
     CDS             12023..12592
                     /locus_tag="LP386_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBL1920250.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12659..13396
                     /locus_tag="LP386_003112"
     CDS             12659..13396
                     /locus_tag="LP386_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL1920251.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            13627..14895
                     /locus_tag="LP386_003113"
     CDS             13627..14895
                     /locus_tag="LP386_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBL1920252.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            15382..15846
                     /locus_tag="LP386_003114"
     CDS             15382..15846
                     /locus_tag="LP386_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL1920253.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            15830..16459
                     /locus_tag="LP386_003115"
     CDS             15830..16459
                     /locus_tag="LP386_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBL1920254.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            16813..18291
                     /gene="msr(C)"
                     /locus_tag="LP386_003116"
     CDS             16813..18291
                     /gene="msr(C)"
                     /locus_tag="LP386_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBL1920255.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            18338..18784
                     /locus_tag="LP386_003117"
     CDS             18338..18784
                     /locus_tag="LP386_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBL1920256.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(18983..19498)
                     /locus_tag="LP386_003118"
     CDS             complement(18983..19498)
                     /locus_tag="LP386_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBL1920257.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            19615..20816
                     /locus_tag="LP386_003119"
                     /pseudo
     CDS             19615..20816
                     /locus_tag="LP386_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
BASE COUNT         6631 a         3703 c         4315 g         6213 t
ORIGIN      
        1 caaggagcaa tttcaaaaaa cagcttctca tgtttgatga atattttgac ttgtgaccga
       61 agagttggta ggagaacacc gtttataaga ggttgtgaca aaagtcttgt cgcaacctct
      121 tttttaacca aaaaagtgca aatagtttac tttaagtaag agaataatta tgatgaataa
      181 aaaaggtgga acaaatagca tactatatat attgaaatga acactgtatg gatgctccaa
      241 cttgatgaag ctaaggagga attcgtatgt cagaaaagga attaatgaag gtagtcggtt
      301 tttatgaagg gttgccgatc gatgatccaa aaagctttat tgatgaaaaa gaacagatac
      361 ctgtacccag ttcacgggat cttctggtaa aagtcaacgc agtatctgtt aatcctgtcg
      421 atacgaaact tcgccaagat aacgggataa gaaatgcttt acgtatctta ggttttgatg
      481 gagtcgggaa agttgttgct gtaggtgacg aagtgcaaaa attttctgtc ggcgatcgcg
      541 ttttttacgc aggtacaaca acaagagcag gaagcaatca agaataccaa ctagttgacg
      601 aacgtattgt cgctcttgca ccaaaaaatc tttcagatga agaagctgca gccttgccgt
      661 tgacctcatt gaccgcttat gaattgttat ttgaaaaatt tggtctaact ccagaagaaa
      721 atgccaatcg cgggaaaaaa atcttagtga tcaacggatc cgggggcgtc ggttcgattt
      781 tgaatcaact agcgcattgg gctggcctag aagtctacgc gactgcaagt ccgaagaatt
      841 ttgaatggct gaaaaaaaca ggtgtagact atccaatcga ttatcatcac gacttaagta
      901 aaagttttcg tgaattagga atcgatcaag tagagtatgt cgctgtatta ttcgatatta
      961 cccgctactt tgatcaaatc aagcaccttg tccgaccatt tggacatgtg ggaacgatcg
     1021 tagggatcaa agagccgtta gatataggtg tttggaaaaa ccaatctatc agcttcgact
     1081 gggagtatat gttcgctaaa acagactata actatgaaat cgaaacgcaa ggagaagctt
     1141 tagcgcacat tgctgcttta gcaaatgaag ggattatccg cagtacattg agcaaggtct
     1201 attcagatgg gatgaatgcg aagaacttga aacaagcaac caaagacgta gaaacaggac
     1261 atatgttagg aaaagtcgtt gttagtggtc cgttcaacgg ataagcaaga atacgccgat
     1321 ttttttctta tttgactttg ataaaaacaa gagcgcatga cagtaatttg ccataagctc
     1381 ttgttttttt atttataata agcgaatcaa cgaaagggaa agaattcctg ccaagacgat
     1441 caccaataag ctttttgaaa gaatagcagc taaaagtgta ggaactgaag ccaaagcatt
     1501 ttcgagattg atctgcggca gatgtccgat attttgggta aatagactgc tgaaccataa
     1561 agcagacata atgacgatcg ggacaaaact taaatactca agcaacggtt gcggtaaatc
     1621 gaattttttc agtaagacaa atggtaggac cctagaaagc caagttgcta aagtacaacc
     1681 taaaatagtc agcaatgtaa actcaaaaga aggcatgttt gatccacacc cccaatccgc
     1741 acccaatcag tgttacaact acaatcacta agttgcttgg gataaaaatc agtccgacat
     1801 ataccagaat caaagtgaga ccaatcagga tcaactgtaa tcgtttagag gtgtttctat
     1861 cagaaatgac ttgaagataa agtaacccga taaacatagc gacgatggcg aaatccaaac
     1921 caaacttttt cggatcagta ataaaattcc ctaaaagtgc gccaacaaga gaagaaccca
     1981 cccacgtcaa ataagaaatc caattagctg tattcatcca acgaaagttt aacttttgtc
     2041 cagtatagtt caatttattc attcccagtg cgaaactttc atctgtcagc aatgtgccaa
     2101 tcagcagatt ttgaagcagc cgatttttct tgaaataagg agcaatcgtc atactcatca
     2161 gaatcattcg ggaattgact agaaaggtcg agaaaacgat ggaaagcaat gggctgtgac
     2221 tagcaagcat gctgactgtg ataaattggg cagaaccagc atagaccagc agggacatca
     2281 acgtgacgac tagtggatga aatccggcag ctttcccaac gataccaaat gcaagtccaa
     2341 taccgatata accgaaaacg gtaggtaacg tgtctttgat cgcagttttt atatctaact
     2401 tttcatccaa taacaaaact cctttagcac gacataaatt ttcataattg tcgttaaact
     2461 tgtgaatatt ctaaattttt aatgagcatt tgtcaatggt gggattgaaa cgtaaagaac
     2521 tagcgggtcg cagatttaca cgtattgttt cggtgggagg aggcgcgaaa aatcttgcat
     2581 ggctacaaat ccaagctgat attttcgatg caacggtcta ttgtttaagt atggaggaag
     2641 gacctgcatt aggcgcaaca atgattgctg cactagggtt agggtggttc gacacacctg
     2701 aaagttgttg tcagaatttt atccaatata cagatgcagc ggaacctctc ttacaaaatg
     2761 tagaaaagta tcataaaatc tatcaacaat gccggaaaat ctatccagca acgaaggaaa
     2821 tttgtcatga cttataaaac aaaacgcgta cctaatagtc aaatgactaa tattgggtac
     2881 gcgttaagtc ttctttactt catcctttgc atgattcgtg tttttaaagc aaggtctgct
     2941 gtatttcttg tggatttagg atggttgtta tcgtttactt gctatttttc attgaaatcg
     3001 tctttcttta ccgtttcttt agttttttat ctattttttt cttttggtta gaaaattctt
     3061 tttcccgaaa gtcttctttc aggattttta tagagtagcg ttttgaataa gaggcgtcag
     3121 tatgatcgac ttggcagacg aaccaagaga acatttgcct tttttctgca tgaggtgctt
     3181 ctgctaataa ttctttccat aaataataac agtcctctat cagaagaagg gttcgttcat
     3241 cctcaggctc ccaatagaat gtttcgagag tagcaatcac ttcattgatc aattcgaatg
     3301 cgggaagata ggcattttgc tgaataagcg attcaactgc ttcttggatg aactttcgca
     3361 tctccatgat gaacttcgct gttttcctgt ttttgttttt cttgataata tgatcgtatt
     3421 tatggatgat agttgttaat ttatctgaat aatttattgc atgaaatggc atcttaactt
     3481 tgaagcgttc gataaagtgc ggatgttcta taagaatctc tgttaaaagc tcccgtacaa
     3541 gagaggaact agcggaggaa acaagggacg agagttcgga aagtgagtag ttggattttt
     3601 ttattggacg ttcttcgtaa gcgaataaga cagcagccat gtgtttgcat ttttttcctt
     3661 ctatggcata tagacaatca caagtcatgt tggtcttttc atcccaagtg atcactacct
     3721 tataatcttc cgtgccagaa actgttgcgg acaagtactt gcttgtatag ttcaaatgac
     3781 ggacaaaacc gtgcagatga tagctgtaac cgcgttccaa aacgttttca ggaaaatact
     3841 caagccaatt attcatctag ttctcctttc atgaaacact tatttatatt tagtataaag
     3901 aaacgtttaa gaaaaaagta gctgatttta catatttgat aatcactttt gctcgaattg
     3961 tcaaaaattc attctccttt tcttttctta gagaatgtga gaaaaagtaa aagaatagcg
     4021 tgttttaaag atggaacttt ttttgttttt tatttatctg acaaaaatga agtgattttg
     4081 ttagaaataa ataattgttc caattgataa aagaggtatg atgtatcgca aagaaaaatc
     4141 caagcagcgt tctgatcagc agtttgaaca acaatttgct ttgtacagta ggtagtaagc
     4201 ggattaacta agggaataaa agatattttt accgctttgt ttacttagaa tctgtcttcc
     4261 ccaaaattta tttttctaaa ggtaaaacat agataggcag ataataccaa ttatccgtta
     4321 cgaaacgctg cttgagaatt ttctttagat ccatacaaca ttttctacat ctgactaaat
     4381 tggttcctga ttcatcaagt aattgacttt ctttgataat atgataaaaa ggcaatcaag
     4441 gaggaagata aatatgctta aagatctgaa ccaattgatc gattacatcg aagaacattt
     4501 gacagaagga ctttcctata aaataatagc cgaaaataca ggaatctctg aatatcaatt
     4561 aaaacgcatc tttacgttta ttgcagggat gtcgctaatg gactatatca aaaaccgtag
     4621 attggctttg gctaatcgcg atcttctaga tggatcaaga gtgacagaaa cggcgtttag
     4681 atatggatat gaaacagtcg aaggtttttc aagagctttt cgtgattggt caggatatct
     4741 gccttcagaa atcagtagat acggcataca aaaatctttt ccacgcttga cattttttat
     4801 tgatgtcaga ggaggaaaat cgatggaatt tcgtatcgaa aagaaagaac agttttatgt
     4861 ggcaggtgtg gcgaaaaaag ttcctgtcaa atttgaagga gtcaatcaag aaatacaaaa
     4921 gttagcgcag acgatcacgg agactcaaag ggaagagatg cataagttag gagatttata
     4981 tccaaatcaa gtaatcaacg tttcttatgg atttgatgga gaccgcttgg aagaaaaggg
     5041 cagtttgatg cacatgattg gctttgctac gacaaaagaa aatccgtacg ctgatttaga
     5101 aatgcttgct atagaagaac acacttgggc catttttcct aataaagggc catttcccca
     5161 aactttacaa gatacttggg ggaaaatcta tgcagaatgg cttccttctt cagattatgg
     5221 gttagtcgaa gctcccgaga tctcttttac aaaatgggga gaggatttca gtaatgttta
     5281 cagtgagatt tggattgcag tgaaagcaaa aaaatagtta aaaaataaaa atatccctag
     5341 aaaaaagagc gtaatcgtgt catttccctt taattttatg taagatgaac ttaatataat
     5401 agaaagggtg ggagaaatgg caaagtatag gatcgaagaa aaaccagatt ttacggtgac
     5461 gggtattggt gtggaattga agagtagcaa tacggatttt gtcggtttgg ctgcagagaa
     5521 acaagcattt gagcaaaaag ttatcggtaa tggaacaata gatgcattga aacaagctgc
     5581 tgaaaatcat tatttcttta cagtcaacga accctataac gggaaaatga tgtactatgt
     5641 cggtgttcaa acgagtcagg atgttccaaa cactacgcga atcatcccat tcccaaaagg
     5701 aacgtatctt gttgtaagcg ctttagcaga atcgcctgaa gaattaagaa atgatttgac
     5761 gaatacggcc tttgggcatg ttttaagaga agtagaagat tacgcctatg ttgggggtcc
     5821 aaatgctgta gtcgaaatgg gagttaccaa cgggaaatat atgggagaaa tctggatacc
     5881 ggtagtcaat aaaccatgat aatatagagg tcgtgaaagt agcgctttga cctgagcatt
     5941 agagaggaaa aatgggaaat agctttccat attttgcatt tttcagaact aatgccgagg
     6001 gtcagctact tgaacaccgt ttatcaagac gtcatgactt cagcgctttg acctgagcat
     6061 tagagaggaa aaaggggcat gacaaggctt ttgtcccccg gagaataaaa gaatttatgt
     6121 agacgattcc gatcagaaaa atgcaggcac agtagagaga attataaaaa tctctctacg
     6181 aggcctgtgt tttctggtct tttttctttt tccaaaacgg ctattttatg tatcagacta
     6241 tcaagtgtga tcttagccat ttcttcttct gcctttttct gcagccgagc gtagctttct
     6301 tctaaagctt cttggatatt cgcaccaacg acgcaatttg gatttgtttt tggatcgact
     6361 tggataagct gtgtattacc ttcgatgctg cgatagacat ctagtaaaga aatctgatct
     6421 ggacttttgg caagggaagg ctgcggtttt ccggtttttg taaagatcaa accggatttt
     6481 ttgagctgac tcatgatttt acgtacattt gctgcatttg tttcgatact actggcaatc
     6541 atctcactag aaagtgatcg ggtatcttga aacatttcaa tataggcaag tacatggatt
     6601 gcatcactaa attgcagaga atacttcatc agttgtcatc ctttcatttt ttttgcttga
     6661 cttatcttac cacactcttt atgataaagg tgtaatttat aaatgtacag ctgtaaatct
     6721 taacaaataa aaagaatagg gagtggcaaa tatgcattat ttagtaacag gagcaactgg
     6781 aggttttggt ggttatgcgc tggaattctt aaaaaagatg gttccacaaa atgaaatcta
     6841 tgtactagta cgtagtgaag aaaaaggaga agcactgaaa gaagctggat ttaatatacg
     6901 tattggtgat tatgatgatt tagactcaat gaaagaagcg ttgaaaggaa tagatcgatt
     6961 gctttttgtc tctggcgttc caggaaatcg tcaagccgaa cataagaatg tagtgaaggc
     7021 agcacaagca gctggggtat cttatatcgc ttatacaagt tttgcagatg ccgatcactc
     7081 gatcagtgta ttagcgccag atcaccaatt cactgaaaaa atgattaagg attcaggtat
     7141 ttcccataca tttttacgga ataattggta tgtagagaat gaattaccta tcattgggca
     7201 ggctttaaaa actggtcaat tcgtttatgc tgcaggaaat ggaaaaacag gttgggcatt
     7261 gaaacgtgaa tatgcagaag ctgcagcaaa agtactagta gaaagtgact ctccagaaat
     7321 cttagaatta tccggcaatc taactgacta tgaagaatta gccaaggcat tagagcgtgc
     7381 gacaggtaaa gagttagaaa ttattgaagc aagtgatgca gcgtttgtcg aaaatctaaa
     7441 agaagccgga ttccctcaag aagcagctga catgttttta gcgatccaac atgatattaa
     7501 aaaggatcag ttagctattt cctctgatga tttagaaaaa gtattgggaa aaccattaac
     7561 ttctcttgaa gcagcattaa aagaaatatt ggatcaggaa taatgtataa agaggttgtg
     7621 aaaaagccga ttagttttga gtatgaagaa aaattttgtg aaaaagctgt tctgcatcaa
     7681 gtaataagaa gagtcaaata aaaaatagct cttcatatgt ttcgtttagc tggacttatt
     7741 accgcggagt tggcaggaga acgccgtttt tattcggaaa aaggagctga gacaagattt
     7801 ttgtctcagc tcctgtttgt ttatcgataa aaaagtctgg ggaagacgat ggctcaggct
     7861 ttgttggaaa cagagccgat tttatcattt gcttttacat cacgtgcggg ttcgatttct
     7921 aagctttgga ctttgtcgcc atttgtgaat acaacgacca tatccgtgtt tttgcctgca
     7981 gattgaatag cggcaagatc aactaaagca atcaattgac ctcttgcgac tttttgacct
     8041 tcttctacat ataaagtgaa tggttcgcct tttaagtcaa cagtgttgat gcccatatga
     8101 agcaagactt cgataccagc atctgtttgg attccgacag catgtttcgt tgggaaaatg
     8161 tttgtgatcg taccagcgat tggagagaag atttctccat tttctggtaa tacagcatag
     8221 ccgtcaccca tcattttttc cgcgaataca tcatctgaaa cttcagtgat tggaatcagt
     8281 ttcccatttg cgatagcgta aatatcttgt tcgatcgttt caccggcaaa tgtttctgtt
     8341 ttaaccacgg tgtttgtttg tgcaggtcgt gctgcagcac caccatgtag ttttgccatc
     8401 tcatctgcaa cgaattgtac ttctgtacct acgatgactt gcgcattttt tccgtcgatg
     8461 atcttcatac caggtacgcc agtggctttg attttatttt gatcgatcag gcctgtatct
     8521 ttgacttgca aacgaaggcg tgtagtacag ttatcgatcg aagttacatt gtcggctccg
     8581 cctaatgcag cgtagatttt gcttgcttgt gccgcatatt tattgtctga attagtcgtt
     8641 gcagtatcgt catctgaaag atctgcttcc tcgcggccag gagtcatcag atggaatttt
     8701 ttgatagcaa agttaaagcc aaagtagtaa atcactgctg ttactaatcc ttggacgatc
     8761 aacatcaatg gctgattcgc aatcggattt ttcaaagata ggaagtaatc gacaaatccg
     8821 gcactaaagg caaatcctgc tgtccaatgg aagaatgcac tcactgctaa agaaatccca
     8881 gtgaaaattg catgcaagac atataatggc caagcaacga acataaatga aaattcaagt
     8941 ggttctgtca caccagtaaa gaatgaagca aaagctgctg ctagcatcaa ggaagctgtt
     9001 tttgctttgt tttctggacg tgcatttctg taaatagcat atgctcctgc tggaagcccg
     9061 aacatcatga ttgggaaaaa tccagcttga tacattcctg ttacgccttt tgttccttca
     9121 gaagccaaaa atttaccaat atcattgatt cctgctacgt caaaccagaa cacggagttc
     9181 attgcttgat gcaatcctgt agggatcagt aaacggttga agaagccata aagacctgca
     9241 ccaccccagc ctaaactcaa aatgaattta gcaaaagaaa ctaaagcaga gtaaaccgga
     9301 ggccatacga gcagtagcac tgcactgatc agcaacatga caaaggcagc caagattggc
     9361 actagacgct tgccgctaaa gaaagataaa gccatcggta attttgcttc gtggaaacga
     9421 ttataaagag ctgccgcaat caatccggca ataataccaa taaatacgtt actgatctga
     9481 gcaaaagatg gatcaactga ttctggtttg atattcaata aagtagctac tgaatcagtt
     9541 tttaaaacat ttactggaac ttcaaatgcg accaaacctg ccaaggcagc agcacctgat
     9601 ttgtccactg acatccctag tgctaaccca acggcaaaca gcaaaggtaa ttgacctaaa
     9661 actgcgttac cgccagcttg taaaaaatga gcgacaatgt cgttactata agatgcccac
     9721 cagtttccga tccctactag taaagcagca gcaggtaaga ccgcaactgg aagttgaagg
     9781 gaacgtccca ttcgttgtag atatgctttc aatttttttc ctcctcatga ttgttaacat
     9841 ttgtttgtac gattgcgctt cttaaacgct cgatatggat ggccaagtaa cccagttctt
     9901 ctttcgtgat cgcgagctgg tattctttgg tcagcaacac acggattttt ttagaaatct
     9961 tatagctttc tgggtatttt cgtttgacca tttctacgat ttccgtgtct aaaacagcat
    10021 attgttgcgc atgggttcgt tgtagaagca gtcgtaaatg attcaccagt cttgaataat
    10081 tcagtgaaaa tggttctgaa tggatatctg tttccaattc tgattccact aaatggatga
    10141 tgtcagatac aatcgtcact tcacggatac tgcgatggtt attgttccga ccgcttcgtc
    10201 cgctgtgaat atggattgcg atatatcctg cttcgtcata agtatatgga atcccaagct
    10261 cttttgtcag atactctact gcccattgag caatactgaa ttcatcactg taaagcactt
    10321 cgatttctct taaaagtttg ttgcggatga cgataccgtt attaatgttc tccgcagaaa
    10381 aagcaatgtg gtcggtcaaa gcgatcaata catgttcatt caacttttcc atcaaaacag
    10441 tttccgcatg atcaatgatc gtttctgctg caaataaaaa gcgttcatca atctgattaa
    10501 gtaaattttg caacttgatt tgaccttctg gttccatgac aaatatccgt tcgacatcac
    10561 gatcaaaaat caaatcattt ctttttctgt caaatccaat cccttttcca atagctactt
    10621 tttcctgtcc accgtcatct accaatactg cattttgatt aaagatcttt ttgattttca
    10681 tgcgcgcacc ctttttgaag atttggtttt cacgtttgct agaccagttg attgcggcca
    10741 aacaaaaata gacacgaaaa acctcctagg gaaaccatgt tcctcagaga tttttcatgc
    10801 ctagtatgat ctagtcacat gaaacgaatt attgttaacg taatcaattt tatatagaca
    10861 gttatgtttt gtcaattctt tttttataat tatagtaatt tactggaatt atcagaaata
    10921 aaaggaagaa ataaattaag aaacttatgt tatttaatcg ttggatcttt tgcttatctt
    10981 attcgttgtt aaaaagctga aagcgaagga aaaaaactct acttaactgt atttctccgt
    11041 taggacatct aaaaatttac gagcagcagg agaaagaggc tggtcttttt tccaaatgag
    11101 attcagtgaa gcttgtaatg gcggatcgag tgggatgaat attttttccg tcccataagt
    11161 attgatgatc ccatctagag ctaatgcacc aaaagtcccg ttatcgacca tcaaagaagc
    11221 attgtacaat aagttatatg ttccgacgat cgataactga tctatgctga aacctagcca
    11281 ttcagctagt tgactgtcca ctgacgtttg ccgggaaatg atcaaaggaa cagttttcag
    11341 ttcctgcgga tggatgacgg tttgctttgc taaaggatga tttcgatgta tcaaaagtcc
    11401 ccaacgatct tgggctggca gtcgaaatga ctggtatttt tgtttgtttg tcggttcgat
    11461 tacgagtcca aaatcaagta atccgctatc cagtttgtct atgatatcat ctgcattccc
    11521 gctatataaa tgaaactgga tatcaggatg cgccttgatc aacgaatgaa ggctatcaga
    11581 aatgaaagag attgctttag tttcgcctcc gccaatgtag atttctccag agatgattgc
    11641 gtcatttgtt aaattgttcg ccgttttttc taccaacgac aagatttctt ttccttttga
    11701 ataaagatat cgaccagaat ccgtcaactg tatctctcgg gagccccgag tgaaaagtgt
    11761 cacaccaagt tcttcttcta aatctttcag ttgttttgag agagtaggtt gcgtgatatg
    11821 cagagatttt gctgctcggc tgatattttt ttctctagct actgctaaaa aatacgtcag
    11881 tatacgaata tccatttttt ccctcctgtt tttaaaaaag cataccacta agtatagtta
    11941 aaaggaatag ttaagtatgt tttataagta ttagacatga taagccgtcc gttataaagt
    12001 aaggataaaa ggagggagca aaatgacaag cctcatcgaa aaacaaatcg tcaataaaga
    12061 gattcgagta acggatccgc tctttgaagt gatccatcag atccaagctg aaaacgaaga
    12121 gcctttagca gcgctgaata ctgggtacca tgaaccagca gatatccgca aacggctaga
    12181 aaatatcatt agtgacaaag tagatgatac ggtgactgtt ctgctgcctt tttatacaga
    12241 tttcggcaaa catattagta tagggaaaaa tgtctttatc aatcgtcaag tgatgttcgt
    12301 tgacttaggt ggcatctgtt tagaagattc agtattgatt ggtcctcgtg tcaacctcat
    12361 cacggtgaac catctaaccg atccaaaaga acgaagaggc ttgtcagtaa agccaatcca
    12421 catcaagaaa aatgcttgga tcggagcagg agcaactatt ctgccaggcg taacgattgg
    12481 cgagaatgcc attgttgcag cgaatgcaac tgttacgaaa gatgtcccag acaataccat
    12541 cgttgcagga atccctgcca aaatcgtcaa acctgtcgaa cggattattt gaacagtaag
    12601 atgaaataag agatagtgag tataagcaag agatttttca aaacaggagg agaatagaat
    12661 gaatgattta tcagaaaaag tgattgtcat catgggcgct tcaagcggaa tcggtgaagc
    12721 aacaacgaag ctattagcag aaaaaggggc taaactagtt atagctgcac gccgagaaga
    12781 tcgcctaaaa gcaataaaag aatctttacc agaagctgag ctatatattc aaacagcaga
    12841 tgtaagagat tttgcacaag tccaagcagt tatcgattta gcgatggaaa agttcggtcg
    12901 aatcgatgta ttgtacaata atgcaggaat catgccaacc gctccattag ttgaaggtca
    12961 ccgtgatgaa tggcaaaata tgcttgatat caacatcatg ggtgtgttaa atggaatttc
    13021 cgccgtactt ccaatcatgg aaaaacaaaa atctgggcat atcatttcaa ctgattctgt
    13081 ggcgggacat gttgtttatc ctgattccgc cgtttattgc ggaacaaaat ttgctgtccg
    13141 tgcaatcatg gaaggattac gtcaagagca acggcaaaat aacatcaaat ctacgatcat
    13201 ctctccagga gctgttcaaa ctgaattata tcaaaccatc agcgacaaaa aggctgctct
    13261 tgaacttcat gaagcgcaaa aagaatgggg attgacctcc gaagatatag cttctgctgt
    13321 agcatttgcg atagaaacgc cagaccggat gtctgtcagt aacatgatta tccgtccgac
    13381 gacacaggaa gtataatcca taacggataa tatccaaaga gaattacttg ttaaatagtt
    13441 attcaaacga ccatcaattt aaggcgtgaa tggagaagaa tattcttcat ttacgtcttt
    13501 ttatgtagaa aaagcaaatt tatcaaaaag aaacaaatgt tatttaaata tggacattga
    13561 cttgctttta cttttttagt tacactgtta tttaggaaaa gtttcataat tcaaaggaga
    13621 aaaaagatga aagcaaagaa tttattattt agcgttattc ttttaggaaa tctagcagtt
    13681 gccaacacaa cagtgctagc tgaagaatcg acagaaactg tcgcaactca gacatcgagt
    13741 tcttcagaaa caggaattga aaacgataca gagagtactt tgcagtcagc tactgtctca
    13801 gaaaatacaa tttcaaccga agaaccaaca actgaaacaa cagaacaaac acaaaccgaa
    13861 gacagtacat cagcagaagc tcagaacaat ccagagaatg cagaagaaat cacgaaccaa
    13921 ttgacagatg ggcaaacatt gacacatacc catcaagcag atttgtctga attcgaaaac
    13981 tatactggct atgcttttta tgctcgctca tctgctaatt ctcaacaagc gttcattgat
    14041 agtattgcct caactgcaca aagtttggca agtgccaatg acttatatgc atcagtcatg
    14101 attgctcaag ccatcgttga aagtggctgg gggaacagta ctttggcttc tgcccctaat
    14161 tacaatctat ttgggattaa aggaagctat aatggccaat ctgttacgat gcctacttcg
    14221 gaatatgtga atgggcaatg gattacggtg aatgccgctt ttagaaaata tccttcgtac
    14281 aaagaatcat tgcaagataa cgtaacggta ttgaagacga cttcttttca gccaggcgtt
    14341 tactactatt ccggtgcatg gaaaagcaat acgaactctt acaaagatgc tacggcttgg
    14401 ctaacaggtc gttatgccac tgcgcctaat tatggttcta cattgaacaa tgtaatcgaa
    14461 acctataatc tgacacagta tgatacagca ccaacttcaa cttctccgat gtatcgtctg
    14521 tataaccgtc atacaggaga acatttatat acattgaatg ccggagaaaa aaattatctg
    14581 ccaactgtag gctgggaata tgaagggatt gcttggcaag caccaaacag cggacaacct
    14641 gtctaccgtt tatacaatcc ttacagtgga gaccatcatt acacaatggc acaatctgag
    14701 atcaactctt taacaaaaat cggttggcgt tatgaaggtc taagttttta ttctggtggt
    14761 tccaagccaa tttatcgact atttaatcca aatgaaaaaa ctggtaccca tcactatacc
    14821 ttgagtgcta aggaaagaga ttggctaaca ccgatgggct ggagatatga aggaatagga
    14881 ttttatggtt attaaaaaga ggtagtgaaa aagctgccct gcatcaagta gtaagaacag
    14941 ccaaacaaaa acagattttc atgttttttg tttggttgaa cttattaccg cagatgcaag
    15001 tttttgaaca ccgtttactc aaaaaaggtt gtgacaacat cttgtcataa cttttttatt
    15061 actgtttaag catactgatc caatttctaa tattcgacgg gattcttgca aaaggcgatt
    15121 tcggaaattt ttggcggtgt aaaattttct actgcagaag agctatcttc tatagtttga
    15181 taagaatcaa taatcttggt tttagcgttg tgctttcttt atcatttttt ccgttcattc
    15241 tacaaaaaat ttcttttctc tatacttttc tattgagagc gtttttttta ttacacagct
    15301 gattctttga cttttttctt tttttattct attattgaca agtcaatcgt tgacgagtca
    15361 attattagaa aggaggaaat tatgtcttta gaagagatta gtcacctttt atatcaaatc
    15421 aaattagccg atcaaaaaat cgtccagatc tttgaagaaa atatcggtat aagtcttact
    15481 agatacgaga tcatgatgag actgaaagaa gaaaatccat tgctacaaag cagtttgcaa
    15541 gaaaagttgc agattgatca aggagcagtt actcgtcatc tgaaggtatt ggaagcaaat
    15601 ggctatgttt cgcgtcagag aaatcctcag aacaaccggg aagtgtatgt agcgctaaca
    15661 gaaaaagccc agaagaaaat cgagcattgt gaaatggacc ataaagatac aggttccgtg
    15721 ctatccccgg ctttcagcga tgtagaaatg aaacaatttc taacactttt agataaattg
    15781 aatacccaac tttgcaatat aacaacagaa acgaaagagg ttaataataa tggaacaaaa
    15841 aaatgatttt tcaacaatta tgactggtag aagatccgtt cgcgtatatg atgaaacata
    15901 caaaatccca cacgaagaaa tgctggaaat gatcaaagaa gcgacgactg caccttcttc
    15961 tgtcaatatg caaccatggc gctttgtggt cgctgaaagc gaggaagcaa aagaaatctt
    16021 gcgtcctttg atccgtttca atacgagaca aaatgatact tcttctgcaa tggtcatgat
    16081 ttttggcgat atgcaatgtt acgaatatgg cgaagaaatc tataaccaag cttacgaatc
    16141 agggaagatg ccaaaagaag tcagagatca acaattagct gcgatcattc cttattacaa
    16201 gagtttttca agagaagaaa tgaacgatgt agtcaaagtc gattctagct tagcggctat
    16261 gcaattcatg ttagttgcgc gtgatcatgg ctatgaaaca aatccaattg gtggattcga
    16321 agcagatcag ttggcagagg catttggttt ggataaagac cgttatgttc cagttattat
    16381 tttatcaata ggaaaagcgg tagaagaagg ttacgagtct gttcgtttag caccagaaaa
    16441 gatcactacg ttcgaataaa aggttttcag ttactattca gtagctattg ctttttttga
    16501 atcgtgtgtg gtaacctaat aaaaaaggag gtcggaaaaa tgactgcatc gatgaaatta
    16561 cgtttcgaac ttttgaataa caactaaata aattcaaaag acatgtataa acaacaattt
    16621 catggatgga gtatgtccat tttttcgaac gacagtagaa taggtgaaag ctatgacaga
    16681 tttggtgatt tagtcatagt tatttcgttc agagtaggaa aagatgtgat gcagtttttt
    16741 tgcaaacaga tttttctgct cttttttagt atcgataatt gttgttttac atgaaatagg
    16801 agtgtaaaac atatggaaaa tttagcagta aatataacaa atctacaagt cagctttggc
    16861 aaccagctag aactatctat tgattctctt cgtgtctatc agcaagatcg tatagggatc
    16921 ataggagaaa atggtgtcgg taaatcgact ttgctcaaac taatagccgg tgaacttttt
    16981 cccgatcatg ggaaaatcca aacagagatc accttcaact acctgcctca attaacctat
    17041 ctcgctgaag caaaggacct aaatttggaa ttagccagtc atttccagtt aagactggaa
    17101 gaaacttcag agcggaaatg gagcggaggg gaagaacgaa agatcgagtt gatacgtctt
    17161 ctttcttctt atgaacaagg gatgcttcta gacgagccaa caacccatct agatagaaaa
    17221 agtattgatc gactgattga agagcttcgt tattattatg gtacgctggt ttttgttagt
    17281 catgatcgct attttctaga tgagctagca tcgaaaatct gggaagtaaa agacggagaa
    17341 atccgagagt tttcggggaa ttatagtgcc tatctcactc aaaaggaatt ggagaaaaag
    17401 actcagctac gagaagcaga gtcgatcatg aaagagaaaa aacgattgga aaaatcgatc
    17461 caagaaaaga aaaaacaagc ggaaaagttg gaaaaagtgt ccagtaaaaa gaaaaagcaa
    17521 caaatcagac cggatcggtt gtcttcctct aaacaaaaag acagtgtaca aaaagccatc
    17581 caaaagaatg cgaaaacatt agagagaaga ctccaaaaaa taggagaaac aaccaagccg
    17641 cagcagatga aacaaatccg ttttccagta ccaaaatctc ttgaactcca cagccgctat
    17701 cccatcatgg gacaaaatgt ccaattggaa agaagtggga gaacattact ggtaaatggt
    17761 gattttcagt tttctttagg taaaaaaatc gcgattgtcg gtgaaaatgg ttcaggtaag
    17821 acaaccttat tagaacatat ccgcaaacaa ggagaaggaa tccttctctc tccgaaagta
    17881 agctttcaag tatatcagca aaagggttat caaatgacat ctgaagaatc catcattcgt
    17941 tttgtcatga gacaaacaga gttttcagaa tcgcttgtcc gtagtttgct gaatcactta
    18001 gggtttgctc aggaaacttt gacgaaaccg ttatgtacat taagtggggg agaagcgacc
    18061 cgtctgacga ttgctttgct ttttactaag ccaagtaatg tgttgctgtt agatgaaccg
    18121 actaatttta ttgatatggc aacgatcgaa gctttagaga agctaatgca aatatatccg
    18181 ggaacgattt tgtttacttc tcatgattct tactttgtcg agcgtacggc tgatgaagtt
    18241 tatgaaataa aagggcagaa aataaaaaaa gtacttacga gaaattttta aatgtgctac
    18301 gatgattttc gtgacaaatt taaaggagtg gtacagattg cctacaaata aaaaagaagg
    18361 aataattttt acaacaatga tgtgtttttt gatggtcttg gggatgagcg cgtataattt
    18421 atggctgcat caagatcttc atttatcaag tttgttgatt ggtctagtgc ctggattcgt
    18481 ggtggctttc attttggatg tcttcatcat cggtgtgctg gcgaaaaaaa ttgcctttaa
    18541 actaccagta aatccagaaa gcaaggtcca aatgatctta actatttcat gcttgatggt
    18601 tttaggaatg gtgacatgta tgtctttatt cggtgtgatc atggaacaag gaatacctga
    18661 tcaattattc tctgcttata tgaatgcttg gaaaatgaat gtgattgccg ctttaccgtt
    18721 gcagttgatc atcgttggcc cgctttcaag aagtgtgcta aaagcaattc aaagtaatga
    18781 atgatggaac actgttattt gaaaaaaggc cttggcatgc tttttgtcat agtctcttga
    18841 atgcagttct agaaaaatag tgatccgaac gataggtttt ggcctgtcgt tcggatcgct
    18901 ttttcttttc caactgtatt gctcttttat tgaagataat ttgctcttca atagatattt
    18961 ctagaaaggt tctgtttatc ccttactcaa aaaactgctg catttgttct cttacttgct
    19021 gacaccattg gagttcctgc tgacaaagca taattctgcg ctggatcaca acataacgtc
    19081 caaattcttg tttcttgtct agcgagaggt cattcaattt tttttgattt ttttgcatga
    19141 ttttgttcag ctgttgttct ctagtgaata gcagtccagt agctgttgtt ttatcgagcg
    19201 tcgaaaaagc atagattttt gctagaaatt catctttttg cgtaggagcg ggagtttcct
    19261 ctttgatcca ttcctctaca agagcacgtc cttcatcagt caagtggtag atcttttttt
    19321 gagagtgctc gtctttgtcc aaaacggtca cataaccctg ctggtctaac ttggcaagcg
    19381 ttgtatagat ctgactgtga tgggcttccc aaaaaattgt gatcagctgc ttcaattcat
    19441 acccagaacg tggtttggat aaaagcacgc ataataatat ataggctaaa gtattcataa
    19501 aaatcctacc tctcgtctta ttttctttat tatatcacag taaagtttcc acgttttaca
    19561 tgtgcatatt tacatgtaaa ataaatcatg tatgatgcta atagagagaa agggatggaa
    19621 atattggaga atcaaataga tatacaagaa caaacaaatg aagaaacaaa ggggaaaagt
    19681 tcagcgctag ttgtagcagc tacctgtatg atcgctttta tgggagtggg tctagtagac
    19741 ccaatcttaa aaacgattgc tgcacagtta aacgctacgc cagctgaaac gaccctgtta
    19801 tttactagtt acatgttagt cactggtgtg gtgatgctat ttacaggttt cttatctagt
    19861 cggatcggtt tgaaaaaaca ttgatgacag gattgtttat catcgttgta ttcgctggtc
    19921 ttggcggatt atctgggaat atcggaatgc tgattgggtt acgtgccggc tggggtgtcg
    19981 ggaatgcttt atttgtctct actgctttag caacgatcgt cagtatttta gttggtaaca
    20041 cagaaaaagc aatcatgatg tatgaagcag cacttggctg cggaatggct gttggccctc
    20101 tagtcggtgg ggtcttgggc agtggttcat ggcgttatcc attttttggg gtagcatttt
    20161 tgatgttttg cggttttata gccctagcgg tacttttacc tgaaactgag aaaccaaaga
    20221 gaaaagtagg cctttgggaa ggtgtcaaag cgttaagcaa tcataaactt cgttcagttg
    20281 gactaatcgc attgttatat aatttcggat tctttacttt acttgcgtat gcgccatttt
    20341 tattgattgg ctattctgaa ttagaagtcg gttttgtatt ttttggctgg ggtgtgcttc
    20401 tggctattgc ttcgattttc gttgcaccgg ctcttgagcg gaagtttacg acttatcgga
    20461 caattttagc agcatttgtc ttattcatta tttgtttgct gttattagga gctggaactt
    20521 ctatgccagt ccttgtaccg atcagcattg tgttagcagg atttttccaa ggaattatca
    20581 atacactgtt gacgacgatt gctatggaaa taccaggtct gcaacgaaac gttgcttcgt
    20641 ccagctatag ttttgtccgc tttttcggtg gagctttagc accatttatt gcaggtgtga
    20701 ttggtgaaca tattggtgaa agctatgcgt tttattttgc aggtgccatt gttcttatca
    20761 gtgtatgttg tatcatttat caccgtaatt attttgctac aaatgaagaa gaataagaaa
    20821 tcagaggttg tgaaaaagct gtcctgcatc aagtcataag aa
//
LOCUS       DAFEKH010000193        18009 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.guided.057, whole genome shotgun sequence.
ACCESSION   DAFEKH010000193
VERSION     DAFEKH010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18009
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.guided.057"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..324
                     /locus_tag="LP386_003120"
     CDS             <1..324
                     /locus_tag="LP386_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBL1920258.1"
                     /translation="SRGILELLREGQQGVTLRTFESMYFQKKLVTDNQAIAHYHFYRP
                     ENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKRFITNDSTIYEQYEYDLS
                     SVENK"
     gene            complement(474..1415)
                     /locus_tag="LP386_003121"
     CDS             complement(474..1415)
                     /locus_tag="LP386_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBL1920259.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            1541..2662
                     /locus_tag="LP386_003122"
     CDS             1541..2662
                     /locus_tag="LP386_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBL1920260.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            2920..4422
                     /gene="eat(A)"
                     /locus_tag="LP386_003123"
     CDS             2920..4422
                     /gene="eat(A)"
                     /locus_tag="LP386_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBL1920261.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            4450..5016
                     /locus_tag="LP386_003124"
     CDS             4450..5016
                     /locus_tag="LP386_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBL1920262.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            5227..6288
                     /locus_tag="LP386_003125"
     CDS             5227..6288
                     /locus_tag="LP386_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBL1920263.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            6291..7187
                     /gene="murQ"
                     /locus_tag="LP386_003126"
     CDS             6291..7187
                     /gene="murQ"
                     /locus_tag="LP386_003126"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBL1920264.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            7201..9183
                     /locus_tag="LP386_003127"
     CDS             7201..9183
                     /locus_tag="LP386_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL1920265.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVHMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(9248..9694)
                     /gene="nrdI"
                     /locus_tag="LP386_003128"
     CDS             complement(9248..9694)
                     /gene="nrdI"
                     /locus_tag="LP386_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBL1920266.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            9905..11329
                     /locus_tag="LP386_003129"
     CDS             9905..11329
                     /locus_tag="LP386_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1920267.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(11510..12283)
                     /locus_tag="LP386_003130"
     CDS             complement(11510..12283)
                     /locus_tag="LP386_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBL1920268.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(12280..13185)
                     /locus_tag="LP386_003131"
     CDS             complement(12280..13185)
                     /locus_tag="LP386_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1920269.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(13339..13659)
                     /locus_tag="LP386_003132"
     CDS             complement(13339..13659)
                     /locus_tag="LP386_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HBL1920270.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            14133..14819
                     /locus_tag="LP386_003133"
     CDS             14133..14819
                     /locus_tag="LP386_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBL1920271.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            14821..15765
                     /locus_tag="LP386_003134"
     CDS             14821..15765
                     /locus_tag="LP386_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBL1920272.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            15964..16608
                     /gene="pcp"
                     /locus_tag="LP386_003135"
     CDS             15964..16608
                     /gene="pcp"
                     /locus_tag="LP386_003135"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBL1920273.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            16687..17964
                     /locus_tag="LP386_003136"
     CDS             16687..17964
                     /locus_tag="LP386_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920274.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
BASE COUNT         5754 a         3194 c         3846 g         5215 t
ORIGIN      
        1 tcgcgcggga ttctggaact gttgcgggag ggtcagcaag gagtgacttt gcggacattt
       61 gaatccatgt attttcaaaa gaaactagtg acggataatc aagcgattgc tcattatcat
      121 ttttatcgtc ctgaaaatat ttttttgctt cgagaacgtg atttagatga attaccggaa
      181 tttctgcata caccatttaa gccaatccta tcagagctat tggaatttta tgatgcagaa
      241 aattgggcaa aacgatttat cactaacgat tccactattt atgagcaata cgaatatgac
      301 ctctcctctg ttgaaaacaa ataaaaaacc tacattttga agagattatg tactgaaaca
      361 aacaagcaca attcttatgg catcatgaga gttgtgtttt ctttttgatc ttttattggg
      421 cttaaaaaaa gagaaccagc tgctgattca gctgattctc atcagagagc cttttattct
      481 gcgccaagga ttccttcttt tgcatggact aattgggtca aaaaggcaca atatggtgta
      541 gcaatatcat atttttgtcc ttttcgccaa atggcaccat tgatgtagtc gatttcagtc
      601 aaacgatggt ttttgatcag gtcttggtac atagatgggt aatgcaaccc gatgttgtca
      661 ggatcataag tagaagcaat atgttggtac acttcttctt gatctagtat gattccttct
      721 tttgctgcga tagaagcaaa ttcagatacg attgttcgaa ccatgctctc tgccgctttt
      781 tgcgcgccta gttcagcaat attacaatcc aaaatcgtgc ataaaccatt caatgttcca
      841 tttacacaag cttttcgcca aatggaataa cgaacgttat ggctatagat cggatttaaa
      901 tttgcttctt gaaagacttc tacaactttt tttgtaaatg cttcgccttc tggttccaag
      961 ttctctagtt cgatttctcc atcacctaac aatgtgactt ttccgggacc agctagacca
     1021 gctgtccaca tcgtgatccc aaataagata tttttctttg gcacatattt ttccagtaca
     1081 tcttcatgac ctaatccatt tagtaaacac aaaacataag tattgtcagt aataatggat
     1141 tggatcgaac aaaacatatc atctaattga ttggcttttg ttaatgctac gatcaagtcc
     1201 acgtgttcgt tgctttcgat gatttcttct ggtgaataga ttggcagttt tgcgaccact
     1261 tctttaccgt taaagtcagc aatcaaccca tttgtacgaa tggcttcaat gtgagcaggc
     1321 caacgatcga tcaagaggac ctcatttccg ctttgatgta gcatcaatcc gattcggctg
     1381 cccattgctc cggccccagc tattgcgatt ttcatgtttt ttctctcctt tattcaatga
     1441 gttccctttt agtatataga aaaatggaag aaaatagcat tgttttgttt gaaaaaaatg
     1501 aaaaaaagtg tcttacttaa gaagaaagtg agggatacag atggatattt tggcggcaat
     1561 tgattcattt aaaggaagtg cttcttcatt tgaactaaat caggcagttc taaatggctg
     1621 ggaagatcgt aaaggaagaa aaatcaatgt gccgattgca gatggcggag aaaatactgc
     1681 agaagcaatc tattacgcgc tcaggggaac atggcgtacc attgatggga tggatctctt
     1741 attccgtcag cgaaaaatca gctatttatt gacaacttgg caaggaaaaa acaccgcagt
     1801 catcgaatct gcacaagcat tggggttaga tctacttgat aaaccaacgg atcaaactat
     1861 ccgacttgct tccagttatg ccttaggaga acttattaaa gatgcactgc ttcaagaagt
     1921 agaacaaatt attgtcactt taggaggaag cgggtgtagc gatggtggtc taggattact
     1981 ccaatccttg ggtgcttctt tagaagggta cacagaagga aatcctttat tatctactaa
     2041 aaaacttcat tttgatcgaa gaaacgttct tgtttctaaa gtaaaattga ttatcgctgc
     2101 agatgttacc aatccatata caggtcaaca aggagctgct tggcaatttg gaagacaaaa
     2161 aggaggaata gatacgacgc tagctttctt agataaacaa gcaggaaaga ttgctcagca
     2221 aataaaagat ttctgggagg tggatttaga tgatattcca ggaagtggag cagcaggcgg
     2281 tattggtgga gccctttttt tgttgggagc gaagatggtt tctggtttcg atttagtcag
     2341 ccaaatcact ggattggaaa aaaagatcga acaagcagat gtcatcatta caggagaagg
     2401 gcggatcgat cagcaaacga tccacggaaa agttccatac ggtgtagcag tgcttgcaaa
     2461 aaaatatcga aaaccaataa tcgctatttg cggaagtaga gaccaagagc tagaaggact
     2521 ttctgatttt ctcccaattg tcttaagtat tcatttgggt ccaataggtt tagaagaagc
     2581 aatggaacac aggcaaacat tagaaaaaac aaaaatctta ggacagacac ttagcagatt
     2641 tttcaccatc ctcccgaagt agttgacaaa atcattttct ttatgctatc gtaatttcaa
     2701 atataggaca aagtgaggga tccgtgcatt gaaaaattaa gtcgattgat gaaagctgca
     2761 ttcagactgt accttgtgga gacaaggaag cagtgtgcag attttcggga ttggcttggt
     2821 tttttcgatg tatgggtctt tttgtgtgta tccaaccctt gcatcctctt tagccagttc
     2881 tgaaaatagg actggtcttt ttttacgagg tgatggaaaa tgtctaaaat cgaaataaaa
     2941 aatctgacat tcggctacga cagccaaggc acattattat ttgaacaagc aaatctaaat
     3001 tttgacacac aatggaaact aggacttatc ggacgaaacg gtcgaggaaa gacaacttta
     3061 ctgaatattc tacaaaacaa actaccttat caagggcaag taatccatca gcaagaattt
     3121 gcctatttcc cgcaacagac aaaagataaa gaacgtttaa cctattacgt gttaaatgat
     3181 attacggatt ttgagatatg ggaaatcgaa agagagctcc aattgatgca aacagatcct
     3241 gaaatcttat ggagagaatt cagcacacta tcggggggag agaagacaaa agtcctactg
     3301 gcacttttat ttgtggatga cactcatttc ccgttaatcg atgaaccaac gaatcatttg
     3361 gatatctctg gtagaaaaca agtagcggct tatttgaaaa agaaaaaaca aggcttcatc
     3421 gtggtcagcc atgaccgggg atttatcgat gaagtagtgg accatgtttt agcaatcgaa
     3481 aaaagtcaac tggaacttta tcaagggaat ttctctatct atgaagaaca gaaaaaactt
     3541 cgtgatgaat ttgaaatggc tcaaaatgaa aaattgaaaa aagaagtcag taggctaaag
     3601 aaaacagcag ctgaaaaagc cgaatggtct cgttcccgag aaggagataa aacaaagaaa
     3661 caagtcggat tcatcgatac tgaatctaga cgagtgaata aaggagcagt gggtgctgat
     3721 gctgcacgga cgatgaaacg atccaaagca atcgtgaatc ggatggagac ccagatcagc
     3781 gagaaagaaa aactattaaa agatatcgaa tatatcgatt ctttgacgat gaatagccaa
     3841 gcgtctcacc ataagcgact tttaagcgta gaagatcttc aattagggta tgaaaatctg
     3901 ttattcgagc caattcattt tacaatcgag cctcatcagc gggtggcgat ttcaggtcct
     3961 aacggtgcag gaaagtcatc cattatccat tatcttctgg gggcattcaa cggcaaggtt
     4021 ataggagaaa aataccagcc aaaacatctg agcattagtt atgcaagcca aaattatgaa
     4081 gacaatcgag gaacgttggc ggaatttgca gagaaaaacc aagtagacta ccaagcattt
     4141 ttgaacaacc tccgaaagct tgggatggaa agagatgttt ttcataacaa gatcgagcag
     4201 atgagtatgg gccaacggaa aaaagtggaa ttggctaaat ctttatcaca gccagctgaa
     4261 ctatatacat gggatgaacc attgaattat ttggatgtct tcaatcaaga acaattagaa
     4321 caactgatct tgaacgtgaa acctgccatg ttactagtgg aacatgatca aaccttcctg
     4381 gataaagtat ctactgagat tatttctctt gagagaatct aacccttgta atctcaagaa
     4441 caacaaggta tggttaaggg gaactttgcc aacgaaggag agaatcacat gctttatgta
     4501 acgagacacg gagaaacaac ttggaacgca caaggattag tttgcggacg ggcagatgtg
     4561 ccgctgactg aaaaaggaca gatgcaggca cagaaactag cagaaaaggt agtagatttg
     4621 cctgttccaa tcacgaaaat catccattcc cctcttcaac gagcaagaga tacagcacaa
     4681 gcagttgctg atcgtctcag cttgccgctg accgttgatg aacgattggt agaaatggat
     4741 tttggggatt atgatggact gccaagcaaa gatgagaact ttcaaaaagc acgtttagcg
     4801 ttcgctgtac gattcccaaa tggggagtca gtcttagatg tgtatgcacg gatcgttcct
     4861 ttattgaaag aatgcatcga agacgaagaa aatgtctatc tgttagtttg ccataatgcc
     4921 ttgataagag tgatcaatgc ttattttcat ccgatgccta atgaggggtt ctttacattc
     4981 atggtagata atacagaatt ggtttcttat gagtaattat gtttttgtgt tatttaaata
     5041 aaatatttca aggcactgct tttgcttagc agtgcctttt ttaggttatg acaattcttt
     5101 tgataatata aactcaacct ttagaaatga aatttaatta ttttaataaa agtattgaaa
     5161 ttttgtttct ttagatatat actctagtca tagaaatgaa gacggataca gaaaaagagg
     5221 gataatatgt ttggcttttc aatatttatg aacgattctt tgtcagaaga gaagaaacag
     5281 tatatccgcc aaatggcatc caatggcttt gtcggtattt tcacttccat gcatatacca
     5341 gaagatgatg tttcggcata tcaaaagcga ttgatcgaac taggaagcga agcgaaaaag
     5401 aataaactag aattgatggt cgatatttca ggagaggcat tggaacgagc gggtttttca
     5461 ttagaagatc taacgccttt gaaagcaatt ggtgtaacag gtttaagaat ggattatcat
     5521 atttccaatc agcagattgc cgactggtca catcaattga aaatcagttt gaatgctagc
     5581 acgatcacgc ctaaagatat cgatgaattg aaagaagcag aagctgattt ctcacagatt
     5641 gaagcttggc ataattatta tccacgtccc gaaacagggc tggacaaaga atggtatcag
     5701 aaaaaaaatc aatggctcaa aattcaaggt ctccttgtcc aaggttttgt accaggagat
     5761 acagagttga gaggcccact atatcaagga ttgccaactt tggaagaaca tcgagggatc
     5821 catcctcttg caggcgctct agatctatta gcaagtaaca cggatattgt ttacatcgga
     5881 gatgcaggtc tgtcagaaaa cgttcaggag caatttgctt ctttccaaaa agaacagaca
     5941 gtcttgctcc atacggaacc tgtagatgaa gaattttacg aatatatatt agggaagcat
     6001 acgaatcggc aagacgatgc aagagatgtc atacgaagcg tagatgcacg ttttcgagag
     6061 attccgccta tcccagcaag aaatacagct acgcgtatga aagggtctat tactttagat
     6121 aacgaaaagt atttgcgcta tatgggtgag atccaattaa ccaaatatga tttgccagcg
     6181 gatgaaaaag tgaatgtagt agctaaagtt atcaaagaag agctaccatt gatcaaccaa
     6241 atcaaagctg gtatgaacta tcaatttata agaaaagaag gaagataaaa atgagcaaaa
     6301 tcaatttaga gaacctaaca acggaacgca gaaaccaaga aacttttgga ttagatgaga
     6361 tgagtatttc tcaagccgtt caactaatga acaaagaaga tcagaaagtg gccgctgcgg
     6421 ttgaaaaaga actgacaagt atcgaaccag tgattgctaa cacgattgag tcctttaaaa
     6481 aaggtggacg tctgatttat atgggagccg gaacaagtgg aagactaggt gtgttagatg
     6541 ctgctgaatg cgtaccgaca ttcggtgtag aaccggaaat ggtcataggt ctaattgctg
     6601 gtggagaaga agcaatgact gtagctgtcg aaggggccga agattcttat gagctagggc
     6661 aagaagatct aatcaagctg aatttgacaa aaaatgatat agttattggt atcgcagcta
     6721 gcggtcgtac accatatgtg atcggtggat tagattacgc aaaatcgatc ggtgctgtca
     6781 caggaacgat ttcttgcaat aaacaagccg aaatcagtaa acacgcggat ttcccaatcg
     6841 aagtcgatgc aggtccagaa tttttgacag gctctactcg attgaagtca ggaacagcac
     6901 aaaaacttat cttgaatatg atttctacta tcagtatgat tggtataggt aaagtattca
     6961 ataacttgat ggtcgatgtc aaaccaacaa atgaaaaact aatcgaacgc tcaaaacgaa
     7021 tcatcatgca agcgacagaa gctgattacg aaacagctga aaagtacttt gaagaagcag
     7081 atcaaaatgt taagctggct atcgtcatga ttttgacaaa tagtgataaa gaggaagctc
     7141 aagcaaaatt agctgaagca aacggatttg taaaagggac cttatgaggg ggaaaagacc
     7201 atggcaaaaa acgaactgac tttggaagaa ctggcaaaac aaatttataa aggggcaggc
     7261 ggcatgggca atgtagaaag cattgtccac tgcatgactc gtgtgcatat gaagatcatc
     7321 aatgatgatc ttgtaaatgt ctctgaatta aaagcgattc caggagtgct tggtgtagta
     7381 gaagatgaac agcttcaagt catcatcgga cctgggaaag tgaacaaagt agcacagcaa
     7441 atggttgatt tggcaggcgt gaaattagga gaaaaacttt cttctgtaag tacagctaca
     7501 gcaaattcat cagcatctgg aaaagaccgt gtaaacgaac gggcacaaga aatgaaagcg
     7561 gcacaaaaat cgaaacaaaa accatctaaa atcaaatcgg tattaaaaga catttctaat
     7621 atctttgtgc caatgattcc tgcatttgtc ggtactggga tcgtggcagg gattgccgca
     7681 gttttagcaa acttagtcac agccggaaca cttgatgcag caacatggca acaatatatc
     7741 gatgtgatga acatcttgaa aaacgggatg tttagctacc tagttatcta tacaggtatc
     7801 aatgctgcac aagtttttgg tgcaacacca actcttggtg gagttatcgg ggccgttgtg
     7861 atgctgacag ggatgaatcc ggaagcacca ctgaaaaact tatttactgg tgaagctctt
     7921 gcagctggac aaggtgggat cctaggtgtc atcttcgctg tttggctatt gtcaatcgtt
     7981 gagaaaaaac tgcataaagt agtacctgat gcggtagata tcatcgttac accaactctt
     8041 tcattgattg ccatcggtct gattgaaatt ttcttcatca tgcctttagc aggtttcatt
     8101 tctgatggca tggtcggtgg gatcaactgg gtacttggcg ttggtggagc atttgccggc
     8161 ttcgttctag gcacattatt cttgccgatg gttatgttcg gactgcatca aattttgact
     8221 ccaatccatg tgcaaatgat tgatgaaact ggtcgtacgc tattgcttcc aattcttgcg
     8281 atggctggtg caggacaagt gggtgcagca ttggcattat ggattcgctg caaaaaagat
     8341 aaagaattaa cagaaatgat caaaggagct ttaccagtcg ggatcctagg aatcggcgaa
     8401 ccattgattt acggagtaac attacctcta ggacgcccat ttattactgc ttgtatcggt
     8461 ggaggtatcg gcggggcagt gatcggaatg atcggaaatg tcggggctat cgctattgga
     8521 ccttcaggag ccgctttgat cccattgatc tctgacggta aatggttagg ctacatcctt
     8581 ggattattgg cagcttatgc tggtggcttc gttgctacat tcttcttcgg tattcctaaa
     8641 gaccgtttag aaaaagaaga attagcgact gaaacagcca cagtaaatga agtgcctgaa
     8701 aaagtagtac ctcaaacttc agctgaaagt gtgactatcc tctcatcagt tgctgacgga
     8761 acagttgttt ctttagataa agcaagtgat ccagtttttg cacaaaagat gatgggtgaa
     8821 ggctactttg tagaaccaga aaacggacat atctattctc cagttactgg ggtagtcagc
     8881 tctgtcttcc caacgaaaca cgctattggg atcacaacgc caaatggttt agaaatcttg
     8941 cttcatatgg gaatcaacac agttgactta ggcggtacgc catttgatgt gaaagtaaca
     9001 gaagggcagc aagtgacacc tgatacgctt gtagcagaag ctgacttaga agcgatcaaa
     9061 gcagcaggca aagaaacatc catgatcgtc ttggtaacca atatggatcg tgtaaaaaac
     9121 tttgtcttgg aaaaaacagg taaagcaaaa gcaaaagcac ctgtgatgga tgtcaaagct
     9181 taatatgata gaaacaatag aaacgaaaga agaaactgaa atctattttt cagcttcttc
     9241 ttttttatta tttattgttt tctgctaaaa tctgataaat tcgtgtcaca tcagatggtg
     9301 ttccccgtaa ttcataatct gccaagaaag gaaagccaaa tgtttgtgca tattgtttgg
     9361 ctgttagaca atactgatta ttgaagtttt tatttccgct accgactaca ccaagacaaa
     9421 gtttatgatt gtcttcatgt tccagatatt cacgcatcgt ttcggtcaag atttctgtat
     9481 caccgttatc taaaccattt ccgccgtcta aataagtagg aacgaaagta aaaaatggtt
     9541 ctgtttcttt cgtaaaatca ctattttcat ggatttcttt taaagtaact tcaggattga
     9601 caggatcttc tgcatgcatt ttttcagcat attctgctag atgtttggca aaggcacgcg
     9661 tatttcctga aatcgatata tataaaatgt tcatggatca tcctccaatt ctttcctttt
     9721 agtatagcat cttttttaag ttttttggtg gtgtaatttg gaaagggact aggcgctttg
     9781 cttgtataat gagaaaaaag ccggtagaat tatatttcta ttaaagtttt tattaattaa
     9841 gtaaaaataa aaaaggtttg ttatactttt tgataaaagc ggttttattt tggaggatgc
     9901 ttacatggat acagagcaac agaaaaaagg aattggttta attccacttg ctgccttagt
     9961 aattggttca gcgattggag gtggcgtatt tggtattatg acggacatct ccggatcggc
    10021 tggcggccca gctattttca gttgggtact cgtaggaaca gcaatgttga tgctctcctt
    10081 gtcgatcaat aatatcaata aaaaacgtcc agatttaaaa ggcgggatct ttagttacgc
    10141 agaagaaggt tttggccgtt tcgctggttt tatcagcggt tggggttact ggctcacatg
    10201 ctggttaggc aacgtagctt ttgcaacatt gttgatgagc gcattaggat atttcttccc
    10261 agtatttgaa ggtgggcaaa atctggcatc gatcgtgatg agtacagtct ttttatgggg
    10321 atatgcatgg ctagtgaatc ggggagtcga aaatgctagt ttcgtcaatg ctatcgtcac
    10381 attctgtaaa ttagtgccat tatttttatt tattgtagta gctatcagca cgttttcgat
    10441 ccaacaattc attgataact tttctagcga cattatattg aatgcgaatg gacagccgat
    10501 cccgttttcc agtcaagtat tgagttgcat catggtgatg ctttgggtat ttgttggtat
    10561 tgaaggagcc tctgtcgtag gttcacgagc aaaaaaacaa tcagatgttg ggaaagcaac
    10621 gattctaggg atattcggct tgattattat ttacgtcttg gtttccatgc ttccatatgg
    10681 gacaatgacg atgaatcagc tgcaaacgat caaggcgcag cctgctatgg gctatgtgtt
    10741 tgaaatgatg gttggtaaat ggggagcagt cgtgatcaac ggcggtttga tcatttcttt
    10801 agttggtgtt tggctctcat ggacgatctt accgattgaa acaatgggaa acatggctga
    10861 agacggactt ttgcctaaag catggggaaa actcaacaaa aatggggcac caacttatgc
    10921 tatcgtattg acgacgttat gtacgaatgt ctttttactt tcattattat tcactgacag
    10981 tgcttataac tttgcttaca cacttggtac agcagctatt ttcttcacgt ggcttttctt
    11041 aggattgtac caaatgaaac tttcttatca gcggaaagaa tgggtccaat ttttagtagg
    11101 gcttttagca agtgcctttc aagtatgggc tatgctagtc gtagccttta atgaagtaat
    11161 gcttgttctt gttcttttct tgccaggcat ttatttttac ctcaaagcac gtaaggagca
    11221 aaacgagcct gtacaacata tccacttaga taagatttta cttataggtg tgacgatggt
    11281 cggagtgatt gcaatggttt tatttgccac tgggatgctt cacgtataga agtataaaag
    11341 aagtataaag agaggttgtg agcctgtcgt ttattcaaaa acatactagg aaaggagctg
    11401 tgacacaaat gttgtcacag ctcctttttc agaataaacg gtgtttaaga gacagccaat
    11461 cggcaataag gctgaacgtc tctttcacag cctctttttt gatgagtcat catacatttt
    11521 ttcgcttaaa tacgagatat cctaatgcta agaacaaaac gatgtaagct aaattaccga
    11581 atagcatttg attagtagaa agatgagtca attgcttcat gatctcttcg tttccaattt
    11641 ggttttgcag attcaacata ctgatcggat tccatttgat ccactcccat ttttggatga
    11701 gtgcaataag gataccagat atgattgacg aagcaaaata aaagacgatt cctgctgaga
    11761 tggatgcgcc ggaactattg ataaagcaag caatcatcaa cactaaactt aaaatcagcc
    11821 ataaaccgat ataactaccc aaagtataag tgaacaagct ttggatcagt gtttgaccag
    11881 tagaaacctt ctccgtgaag gaaatcgaag ggaaaagaat cagtttcatc aacacagtga
    11941 caataatagc taaaaggtat aaataaacag aataaataac taatgtgatc catttgctta
    12001 ctaatatttc tcctcgagaa tactttcgat aaaggagatt tttcaatgta ccatattgtg
    12061 cttccatcga aatgatcgtg cttgcagctg caatcatgat aaagacaatc caagatgtgg
    12121 cactaaaaag ctgagcagtc atttcaactg gatcaatgat cgtcgtgtat tttttggcta
    12181 gaagtgctgt tcctatgagc aaaacaacta atagaacaga taaaacagca gttgactttt
    12241 tcttgatcaa tttaaataat tcttgtttta caagcaatgt catttttctt cttccccctt
    12301 tactgaatcc agaatttcca atagagaaga ttccaaatca ttcgtcagat gctggacgtc
    12361 tgtcacatgg atattttgtg cagacaatag ctggatcacg gttcctaata attcttcgtt
    12421 ttcttttaaa agcttgattt tatcaggatc ttccaaagta tatccagctt ctgtcaagat
    12481 cgttcgagca gctagatcat ttgttgtaga gataacgatg aaatcttgcg ctgtttggtt
    12541 caattcagcc attgtacatt gtttgatgat ctttccttga ttgatcagga tcagctcatc
    12601 gaccattttt tcaagctcgc tgagtaagtg actggagatc aagaaagagg tgccctgagt
    12661 agccaagtcg gtaatgattt ttcgcacatc tcttgttgct tgtggatcca aaccgttcat
    12721 cggctcatct aaaataacga tagacggatg gttcagtaag gcaagagcaa ttcccaattt
    12781 ttgtttcatt cccaacgagt aggatttagc ttttttgtga atgtactttt ccatcttgag
    12841 ctgattcacg atagtgtcga tagcagatac atcgttggtt tcagagaata acttcagatg
    12901 atcatagcct gttaagaatg gatagatacc cgggtattcg atcaatgctc ctacttgttc
    12961 caacccttta tgactagagg gagaaatctc attttcacca atacagattg ttccatctga
    13021 gtaatggatc agtcctaaaa tagctttcat gatcgttgtt tttccagcgc cattaggacc
    13081 tactaatcca acgattttgc caggggataa gctaaaactg acatcgctga gggcttgttt
    13141 gtgaccaaag ttcttggata attcttggac cgaaagactt ttcaaaaata ttcactcctt
    13201 ttctatagat agtacaagca tacacctgat gagtggagaa gtcgctaggt cattggactt
    13261 atttcttatt ttttcataaa aaaattgaat attaaataaa aaggcttatt ttttctgatc
    13321 agtacttatt ccaagtgtct agtggccgct agtaatcttg atgccaatga tactgatgag
    13381 tagcatcccc acaaagaacc aagtggaaag attcagctta tcatgaaaca agaccacacc
    13441 aattatgacc gaaccaactg cgccaatccc tgtccagata ggataagaga gactcatcgg
    13501 caaacttttg attgcctttg acaaaaagta aaaactagca atcatgccaa tcactgtgta
    13561 aaaagaataa ttgattttag aaaaaccatc actccatttc atcatcgttg accagaatac
    13621 ttccaaaatt cctgctatga ttaattccat ccatgccata cttacattcc tccttaacta
    13681 taaaaaaata cacaaaaaga ggaaaatcat cccttcaaag acctaatgga atgatcatcc
    13741 tctttatcct acccggtggc agattgtata tctttttctg tagtatagca cacctatcca
    13801 gatatcggca atctcatact ttttagtaaa gtgtaccaag cactgacgga tatatcgtta
    13861 gcggaaaaga agatgaatgc tttgcaattt catagaaaga agttgttatt tattaatcat
    13921 ttaaaaaaaa cagtaactag accttatttc tatatattat cgggcaataa attaaaaaaa
    13981 gctttacctt acaataagta agataatttt tgtgataaaa aaataacgaa aaatatttaa
    14041 aaatagtgtc tatttcgtga gaaaacaact atatttttta tgtgttttgc tttataatta
    14101 aaaaaatatt gtcattttat ggaggaaaat atatggaaaa ttatcttagc cttttaggcg
    14161 tcttgattgt tattctcggg tttgcattta aattagactc gatattgatc gtaatggttg
    14221 ctttagttgt tacagctttg actggcggtc ttggcattca aggaatgtta gaacttttag
    14281 gtacaagttt tgtaaacaat cgcgggatgg cgatttttat catcattatg ttggcaacag
    14341 gaacgcttga aagaaatggt ctgaaagaat cagcggcttc cttgatcaag cgattcaaga
    14401 aagtatctgc tggtatgatt gtagatattt atgggatctt tcgaatgatc tttgcggctt
    14461 ttaacgtgag ttttggtgga gttgctggat ttgttcgtcc aatcatttta ccgatggcat
    14521 tggggaccat cgaatcaaaa gggttagaag tccatcctaa gcatgaagaa gaactaaaag
    14581 gtatggcttc agctatggaa aatgtctgct ggttctttgg ccaagtacta ttcatcggag
    14641 gagcaggggc gttgctagtc caatcaacac tgaaagatct aggatatgac gtaacattgg
    14701 gacagcttgc tttagtggaa gttccagtgg ctatcacggc tttagttgtg gcaagtgtct
    14761 acttctatct taaagaaaag aaattagcga agaaatatta tccaggaaag gggcaataag
    14821 atggactttt ttacaaatcc tgatatttta ttaggcgata aattactgga gatcctttat
    14881 atcgtgatgg gactcgtatt gatttacact ggagtaagaa atttaacaga taaaaccaat
    14941 cctcatcgtt atgggtcagc ctttttctgg acggtcttag gggtagttat tgcaggagga
    15001 agatggcttc cggcaatcgt gaacggtggc ttgatctttg cgatgaccat accagcaatt
    15061 gctaagaaag tcagcaaagg agaaagccgg cttccatcaa aagaatatat ggaaaaaatg
    15121 tcagacaaac taggaatgaa aatttttatt ccagctttga gtatcggtgt ctttgcgatc
    15181 ttgtttgctc tatttaccaa tttaggtgct ttagtcggcg tgggcgtcgg tgtttttgca
    15241 gccatgctaa tcttgatgtt cttttctcga gataatcgac caagtacatt tttagatgat
    15301 gcagcagata tgctgggcac agtagggccg ttaagcatgt tgccaatgct tttagcttct
    15361 ctaggtgcgg tatttacaag cgctggagtt gggacagtga tttccaatgc agtaggtacg
    15421 atcgttccag aaggaaatgt gaacatcggc atcatcattt acgctcttgg catggtgata
    15481 tttacggtaa tcatggggaa tgcatttgcg gccatcaccg tgatgacggt tgggatcggt
    15541 gcaccattcg tatttagtca tggagcgaat ccagcgttaa taggaatggt tgcattgact
    15601 tgcggttttt gtgggaccct gctgacaccg atggctgcta acttcaatat cgtgcctgta
    15661 gcgatgctgg agatgaaaga caaatacgga gtgatcaaaa accagttgtt tattgcgtta
    15721 tttatgctag ttttccaaat tgcttatatg attctattta aataatagaa gagaggggtt
    15781 gtgacagaat aattgtcgca acctcttcta acattgtagt ggaacactat ttttttataa
    15841 gaatatatta agtttgatct gttatgttat ttaaactatt gtttccttta tttacgctgt
    15901 tcaaggaaaa tggtatgata aaagataacc atatgttaaa tcaatcggac ggaggaacaa
    15961 cagatgaaag tactagtaac aggttttgat ccatttggtg gggacaaagt gaatccagcc
    16021 tatgaagcag taaaaaaaat gccagatgaa atcagcggtg ctgaaatcat caaagtggaa
    16081 gtaccgaccg tattcgaaaa aagcagtcaa gtagtcaaag aagccatcca acagcaccaa
    16141 ccagatgtcg tgatctgtgt cggacaagca ggtgggcggt cagcagtctc gttcgaacgt
    16201 gtcgcaatca atctagcaga agcaagaatc cctgataatg aaggaaatca gccattcgat
    16261 acggctttag aagaaaacgg tccagccgct tactttacct cattgccaat caaagcaatg
    16321 acaaaaaatg tacaagatca tggtctacca gcgtacatct cttatacagc aggaacattt
    16381 gtctgcaatg atatcatgta tcgtttgctt catttgatcg aaacacaatt cccggcaatt
    16441 cgaggtgggt tcatccacgt gccattctca cccgatcaag tgatcgatcg tccagtgggt
    16501 acgccttcta tgtctttaga agacattgct tcttctttga cttatgcagt tgaagcagca
    16561 gtagaaaata aagaagatat ttccggaaat gccggaacaa ctcactaatt tagcaagaaa
    16621 cactggctgg ttgctaacgt tatgttagta gccagctttt tgtaattaga aaggaaagaa
    16681 acagccgtgg aagaatggca atccgtcttt gaagaatggt ttccaaaaga aatcagcaaa
    16741 agctatccca tcaaaatttc taaacaatac acaagcagtc aacgttggga gatctatgca
    16801 aaattaacga aaaaacagcg ggaactagtc gataagcacc gccgatatct aatcagctct
    16861 cgttttatgg aagaacatta tttagctgca acagattggg tgttttctga cttcaagatc
    16921 aatccgtttt ttcgaacaaa acgaagccag caaaaattgt attgtgagtg tggtagagaa
    16981 ttaaaagtgc aatacatcgt taaatcgcca aaaaccggaa agatcctaaa actaggcatc
    17041 aaccactttg ccgatcacct gcatgtctct ccgacagtgg cagcttcgat ccatcaggga
    17101 atgacaaaag ttgatctggc cttagacgaa ttattatggc ttaagcagaa gaatatcgat
    17161 tttcctgaag gactatggca aaaatactgt tttgtcttgt accaaaatcg tcggatgaaa
    17221 cagccatatt taccggatat aaaattagct cagcggctcg cagaatttcg ccaagtagaa
    17281 atgccgattt acatagcgga ttatcaagca ttggaaaatg aaatcaagaa aataagtgaa
    17341 cacatcaatg ggcagtcaaa aaagcgacag ataaaaaaag aactatttga cgactttgca
    17401 gaagaattag taaaggatgt agaagaattc ttgatcaact atcgcgcatt tttacgtaaa
    17461 gattggcaat ccatcgtata tgaagaagtg ccagtacatc ctaatgctta ttttgaaaca
    17521 tttatttccg tgttgagaaa gacaaaacgt caacgaacac cagaagtcac tgctcagatg
    17581 gaatattttg cgaaaaacca acgattcatc caaccaaaaa tctatctatt tatttggaag
    17641 caatattgtc gctatggttt tacagaaggg ttcttcgaca gcattcctcg gatagtcaga
    17701 aatggttttt taaaagtatt gcgtaaagaa cgagaagcta tacaatctgc tgataagaaa
    17761 gaccgtacag tctcaaaaga aaaatggcaa ctagtagtga aagatatcca atctggaaat
    17821 gtgcaagaga caatcgacaa atggaaagga aaacattatc gttttactga agctcagaaa
    17881 caagcgttgg aatattatca gaagttagaa gaatcactgc gtttcaatga tgaggcaaga
    17941 aagtatctga aggaattact ataaaaaata gaggctggga cagaagcgtt taactccaag
    18001 aaataagaa
//
LOCUS       DAFEKH010000194         6022 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.guided.106, whole genome shotgun sequence.
ACCESSION   DAFEKH010000194
VERSION     DAFEKH010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6022
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.guided.106"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            187..852
                     /locus_tag="LP386_003137"
                     /pseudo
     CDS             187..852
                     /locus_tag="LP386_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            888..1133
                     /locus_tag="LP386_003138"
     CDS             888..1133
                     /locus_tag="LP386_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBL1920275.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            1236..2105
                     /locus_tag="LP386_003139"
     CDS             1236..2105
                     /locus_tag="LP386_003139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HBL1920276.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            2086..2820
                     /locus_tag="LP386_003140"
     CDS             2086..2820
                     /locus_tag="LP386_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL1920277.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            2853..3765
                     /gene="ant(6)"
                     /locus_tag="LP386_003141"
                     /pseudo
     CDS             2853..3765
                     /gene="ant(6)"
                     /locus_tag="LP386_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
     gene            3762..4304
                     /gene="sat4"
                     /locus_tag="LP386_003142"
     CDS             3762..4304
                     /gene="sat4"
                     /locus_tag="LP386_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HBL1920278.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            4397..5191
                     /locus_tag="LP386_003143"
                     /note="aph(3')-IIIa"
     CDS             4397..5191
                     /locus_tag="LP386_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HBL1920279.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            5467..6009
                     /locus_tag="LP386_003144"
     CDS             5467..6009
                     /locus_tag="LP386_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBL1920280.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMIEPVLLQSFK"
BASE COUNT         2067 a          902 c         1320 g         1733 t
ORIGIN      
        1 gattttatct ctttttcaaa ataaacatgg ggctgaccca aaagtagctc ctatatgaaa
       61 aatagaggtc tttccattta gatagtagtg gaaagacctc tatttatctt ttgaaagtga
      121 atacaaaaat aaagcacact ctgctataat ataggtgatt aatccatttg agagaggtgc
      181 tttatcatgt atcaaaatta taccataaac caactttgtt tgcctataga tcttgaaatt
      241 aaattagaag aaaatgattt tgctcatgcc attgtgcagt ttgttgactc tattcccgat
      301 gaagtctttc ttccttatta tcaatctatg ggtagacccc aatatcatcc tcgtatgcta
      361 ctttccatta ttctttgtgc ctatattcaa ggggtttatt cgggccgcca aatacaaaat
      421 atgctgatag atagtattcg gatgcgctac ttatctcaag agcaattccc taactttcgt
      481 actattaatc gttttcgcgt tcatccgatt atgaacgata ttctagatca ttcatttgtt
      541 caatttcgtg agctactggt tcaaagtggc ttaatcagtg gcagtgctct atacattgat
      601 ggtacaaaaa ttgaagcgga tgcgaataaa tactctttcg tttggaaaaa aagtatttta
      661 aagtataagg atagccttga tcaaaaagcc cttgaaaact accaacaaat ggtggaaaca
      721 aaaatcttac ctgagttaat agatgattta aaggatgaac tttctataga agagattgaa
      781 aggattcgtc aatctttgga agaaaaggaa aatcaattaa ttgaagcgat tgaccaaacc
      841 gaaacagtag aagggggctg acccattatt aataaggagt ggacaacatg attgatgtaa
      901 atgagctatt ggaagaagct attagagaaa ctgaaaatct aaatgatggc gaagtttttc
      961 ttgttaaaga tttattcaag ggatatgtgg ggaataggat acccagaaag gatcgacttc
     1021 tgcttggaac gttattttta aaccatgtta gcaaaatgaa tggtaattta aaggctattg
     1081 aaaagacttc atctaatcag cagaggtata aaaagacaat tgataagttt taactatctt
     1141 ttgtgaaatt aaaaaaatta taaatatgtt gagtagaagc aaaagatttg gcttggaatt
     1201 tttacagcag tgaatcgata aaaggagcat gcttgatggt agataatatt attaaatcag
     1261 tagcagagaa attatcctct ctgtcttata tagaaggtat tgttttaggt ggttcacgtg
     1321 caaggggcac ccatacagag gattcggata tagatatcgg catctattac aattcagaat
     1381 catttgacat aaatactatt aatcaattcg ctacaaagct ggatgatgag catagaaata
     1441 accttgttgt acctcccgga gcatggggtg attggattaa tggcggcgga tggttagtca
     1501 taaacgggta tcatgtggat ttaattttac gtgatattaa acgtgtggaa caaataatga
     1561 aagatacaga gcacggaatt gttactgcca attatcagac tgggcatccc catggttata
     1621 ttagtgcaat gtatcgagga gaattagcga ttagcaaaat actatatgct aagaatgaaa
     1681 gcttatgcga attaaaaaaa caggcagaaa cttatcccaa tgctttgcag aaaagtttag
     1741 ttaacttttt tatgtttgaa gcagggttct ctttaatgtt tgtaaaagca aattcgggaa
     1801 cagacgataa atattatatt gcgggtcatg tttttcgtat agtttcatgt ttaaatcaag
     1861 tgttatttgc atgtaataat gcttattgta tcaacgaaaa gaaagctata aaactgcttg
     1921 aaacttttga acataaacct gaaaaatata ccgagaaggt aaatcatatt tttgaagtac
     1981 tcggtatctc actttttgaa tgctacgaca tgaccgagaa gctttataat gaagtgaatg
     2041 aaattgtatc ggagataaat aactttttaa acgaggagag ttcagatgaa agaaaacaaa
     2101 tatgatgata atatattttt tcaaaaatac agtcaaatga gtcgctcgca gaaaggactg
     2161 gctggtgcgg gagaatggga gactttgaaa aagatgctac ctgattttaa gggtaagcgt
     2221 gtgcttgatt taggatgcgg ctatggatgg cactgtatat atgcgatgga aaacggtgct
     2281 tcctctgtag taggtgttga tatttctcat aaaatgctcg aagtagcaaa aggaaaaacc
     2341 cattttccac agattgaata tgaatgctgt gccatagaag atgtggattt cccagaggag
     2401 agctttgatg taatactaag ttcgcttgcg tttcattatg tagcagacta tgagaattta
     2461 ataaaaaaga tatataggat gctgaaggct ggtggcaatt tagtttttac agttgaacat
     2521 cctgttttta ctgctcatgg aacacaagac tggtattata acgaaaaagg agaaatactg
     2581 catttcccgg tggacaatta ttattatgag ggcaaacgga cagctatgtt tttggaagaa
     2641 aaggttacaa aatatcatag aacactgacc acatatctaa atacactgct ttcaaatagt
     2701 tttataataa atcagattgt ggagccacag ccgccagaga acatgatgga tattccgggg
     2761 atggcggatg aaatgcgacg cccaatgatg ctgattgtat cggcaaaaaa gaagatgtaa
     2821 taatatagaa aaaataaacg aggagtatgt aaatgagatc agaaaaagaa atgatggatt
     2881 tagtactttc tttagcagaa caggatgaac gaacgtattc gaattgtgac ccttgagggg
     2941 tcacgcgcaa atattaatat acctaaagat gaatttcagg attatgatat tacatatttt
     3001 gtaagtgata tagaaccgtt tatatctaat gatgactggc ttaatcaatt tgggaatata
     3061 ataatgatgc aaaagccgga ggatatggaa ttattcccac ctgaagaaaa gggattttcc
     3121 tatcttatgc tatttgatga ttacaataaa attgatctta ccttattgcc cttggaagag
     3181 ttagataatt acctaaaggg cgataaatta ataaaggttc taattgataa agattgtaga
     3241 attaaaaggg acatagttcc gactgatata gattatcatg taagaaagcc aagcgcaagg
     3301 gagtatgatg attgctgcaa tgaattttgg aatgtaacac cttatgttat taaaggattg
     3361 tgccgtaagg aaattttatt tgctattgat cattttaatc agattgttcg ccatgagctg
     3421 ctgagaatga tatcatggaa ggtcggcatc gaaacaggct ttaaattaag tgtaggcaag
     3481 aactataagt ttattgaaag gtatatatcc gaggatttgt gggagaaact tttgtccacc
     3541 taccggatgg attcctatga aaacatatgg gaagcattat ttctatgcca tcaattgttc
     3601 agggcggtat ccggtgaggt ggcggaaagg cttcattatg cctatccgga gtatgatagg
     3661 aatataacaa aatataccag ggacatgtat aaaaaataca ctggtaaaac cggctgcctg
     3721 gatagcacat atgccgctga tatagaagag aggcgggaac agtgattaca gaaatgaaag
     3781 cagggcacct gaaagatatc gataaaccca gcgaaccatt tgaggtgata ggtaagatta
     3841 taccgaggta tgaaaacgag aattggacct ttacagaatt actctatgaa gcgccatatt
     3901 taaaaagcta ccaagacgaa gaggatgaag aggatgagga ggcagattgc cttgaatata
     3961 ttgacaatac tgataagata atatatcttt actaccaaga cgataaatgc gtcggaaaag
     4021 ttaaactgcg aaaaaattgg aaccggtacg cttatataga agatatcgcc gtatgtaagg
     4081 atttcagggg gcaaggcata ggcagcgcgc ttatcaatat atctatagaa tgggcaaagc
     4141 ataaaaactt gcatggacta atgcttgaaa cccaggacaa taaccttata gcttgtaaat
     4201 tctatcataa ttgtggtttc aaaatcggct ccgtcgatac tatgttatac gccaactttg
     4261 aaaacaactt tgaaaaagct gttttctggt atttaaggtt ttagaatgca aggaacagtg
     4321 aattggagtt cgtcttgtta taattagctt cttggggtat ctttaaatac tgtagaaaag
     4381 aggaaggaaa taataaatgg ctaaaatgag aatatcaccg gaattgaaaa aactgatcga
     4441 aaaataccgc tgcgtaaaag atacggaagg aatgtctcct gctaaggtat ataagctggt
     4501 gggagaaaat gaaaacctat atttaaaaat gacggacagc cggtataaag ggaccaccta
     4561 tgatgtggaa cgggaaaagg acatgatgct atggctggaa ggaaagctgc ctgttccaaa
     4621 ggtcctgcac tttgaacggc atgatggctg gagcaatctg ctcatgagtg aggccgatgg
     4681 cgtcctttgc tcggaagagt atgaagatga acaaagccct gaaaagatta tcgagctgta
     4741 tgcggagtgc atcaggctct ttcactccat cgacatatcg gattgtccct atacgaatag
     4801 cttagacagc cgcttagccg aattggatta cttactgaat aacgatctgg ccgatgtgga
     4861 ttgcgaaaac tgggaagaag acactccatt taaagatccg cgcgagctgt atgatttttt
     4921 aaagacggaa aagcccgaag aggaacttgt cttttcccac ggcgacctgg gagacagcaa
     4981 catctttgtg aaagatggca aagtaagtgg ctttattgat cttgggagaa gcggcagggc
     5041 ggacaagtgg tatgacattg ccttctgcgt ccggtcgatc agggaggata tcggggaaga
     5101 acagtatgtc gagctatttt ttgacttact ggggatcaag cctgattggg agaaaataaa
     5161 atattatatt ttactggatg aattgtttta gtacctagat ttagatgtct aaaaagcttt
     5221 aactacaagc tttttagaca tctaatcttt tctgaagtac atccgcaact gtccatactc
     5281 tgatgtttta tatcttttct aaaagttcgc tagatagagt tctatattag agatgtaaag
     5341 agttttggtg aagaggtttg tgagtatggc ttttataacc agggtgcaat gagaagcact
     5401 aacagcagct agcttaagaa cgcataggat atacttttta tggaagtcac agaggaggaa
     5461 taaaatttga acaggattaa cagagtaacc tctattctta ttcagctgca atcaaaaaaa
     5521 ataattcctg ccaaagaaat tgcacagcga tttaatataa gcttaaggac agtttacaga
     5581 gatatccgga cacttgaaga agccggaata ccaattggat ctgaggccgg aaaaggatat
     5641 tttcttgtag agggcttcct acttccgccg gtaatgttta cagcggcgga agtgggtgca
     5701 ttgattacag cagggaaatt tttaaattgc catggagatg aatcatttat aaaggatttt
     5761 gattcagcta tgtataaaat caaatctatt ttgaagcatg gtgaaaaaaa ctatgcacag
     5821 gagttggaga acagtattaa cgtgtacagc acatctggac agaaaaatac attggcggat
     5881 aacgttattg cagcaattca gactgcaatc tgcaataaaa gggtaatatc aattcaatat
     5941 cctgcatcag gagggcaaga accggaaagc agaatgatag agccggttct gttgcaaagt
     6001 tttaaataaa gaataaaatc cc
//
LOCUS       DAFEKH010000195         5450 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.guided.112, whole genome shotgun sequence.
ACCESSION   DAFEKH010000195
VERSION     DAFEKH010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5450
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.guided.112"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            complement(485..2635)
                     /locus_tag="LP386_003145"
                     /pseudo
     CDS             complement(485..2635)
                     /locus_tag="LP386_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
     gene            2781..3356
                     /locus_tag="LP386_003146"
     CDS             2781..3356
                     /locus_tag="LP386_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1920281.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            3570..4265
                     /gene="vanR"
                     /locus_tag="LP386_003147"
     CDS             3570..4265
                     /gene="vanR"
                     /locus_tag="LP386_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBL1920282.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            4243..5397
                     /locus_tag="LP386_003148"
     CDS             4243..5397
                     /locus_tag="LP386_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HBL1920283.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT         1700 a         1044 c         1043 g         1663 t
ORIGIN      
        1 tatttgatag tagatttaaa actttgcaac agaaccaaga aacctaaaaa tattcgtata
       61 atgaacttga gttacggaac taggtgaagt agtttccgta aaggtcgaga gtgcgtcaac
      121 actgctcgac tattttttta ctcttttttc tcattttctt tgattatagc actcctctag
      181 aaaaaataaa aagacctcag ggaatttcat tccccgaacc ccttgagcct cctcctgccg
      241 aaatagaatg gcgctgccag catttatttc gttcagctat cggctacaca atctaacacg
      301 accgttccgc taccagtcgc cttacaggct ccattttcgc tcctctaacg tgtttcaccg
      361 attgtgccga taactaaacg aaataaacgc taaaaccgct cagaacgcaa aatatgccat
      421 tttagagcta ttgtagaaaa tatagtttga aatgcaattt tcttctttca gctttttatt
      481 tcccacttgt aaatcggtag atggtggctc cttttccagt tccataatgt ggatttgcat
      541 ctgcatgtag tgatgaaaca cctagctgca ttctcatacc atctgacgaa gatgttgtac
      601 cgtcgcccca atagaaaggc aattgtaatt tatgatgaaa gtttactaat atggcttggg
      661 ctttattcat ggcatcttca tacatgcgcc attgagatac attggctagt tgcttatatg
      721 taagtccggg tgtggcttcg gccatcttgc tcaagccaat attcattccc attcctaaaa
      781 gggcagccat gataatgatt gtttcttcct tatctggttt tcgattattg gaagcatgag
      841 tgaattgctc atgaaatcct gttatatggg ccacatccat gagtaaatca gttaatttta
      901 ttcttggtag catctgataa aggcttgcac taaatttttt tgcttcttct ggaacatctt
      961 tttctaagcg tgcaagtgat agctttcctt tttcaagaga aaccccatct aacttattgg
     1021 aattggcagc taaccacttt aacctttcat taaagctgct ggttctctcc gttatataat
     1081 cttcgaatga taaactaact gataatctcg tattcccctt cgattgattc catgtatctt
     1141 ccgaaaacaa atattcctca aaatccctat attgtctgct gccaacaatg gaaacatctc
     1201 ctgcccgaac atgctcccga agttctgtta aaacagccat ttcatagtaa tgacgattaa
     1261 ttgttgtacc atcatcctcg tataaatgtc ttttccatcg ttttgaaata aaatccacag
     1321 gtgagtcatc aggcactttt cgctttccag attcgttcat tcctcggata atctcaacag
     1381 cttgtaaaag tggctcattt gcctttgtag aatgaaattc caatactctt aatagcgttg
     1441 gcgtatattt tcttagtgaa taaaaccgtt tttgcagtaa gtctaaataa tcatagtcgg
     1501 caggacgtgc aagttcctga gcctcttcta ctgaagagac aaaggtattc cattcaataa
     1561 ccgattctaa aaccttaaaa acgtctaatt tttcctctct tgctttaatt aatgcttgtc
     1621 cgatgttcgt aaagtgtata actttctcat ttagcttttt accgttttgt ttctggattt
     1681 cctcttgagc cttacgacct tttgataaca aactaagtat ttgcctatca tgaatttcaa
     1741 acgctttatc cgttagctcc tgagtaagtt gtaataaata gatggttaat atcgaataac
     1801 gtttattttc ttgaaagtca cggaatgcat acggctcgta tcttgagcct aagcgagaca
     1861 gctgcaacag gcggttacgg tgcaaatgac taatttgcac tgtttctaaa tccattcctc
     1921 gtatgtattc gagtcgttct attattttta gaaaagtttc gggtgaagga tgacccggtg
     1981 gctcttttaa ccaacccaat atcgttttat tggattcgga tggatgctgc gaggtaataa
     2041 tcccttcaag cttttctttt tgctcatttg ttagagattt actaaccgta ttaaatagct
     2101 tcttttcagc cattgccctt gcttcccaca ccattctttc aagtgtagtg atagcaggca
     2161 gtataatttt gttttttctt agaaaatcta tgcattcatg cagtagatga atggcatcac
     2221 cattttccaa agctaattga tgaaggtact taaatgtcat tcgatattca ctcagggtaa
     2281 aagttacaaa gtcgtattca cttcgaattt ctttcaaatg atcccaaagt gtattttccc
     2341 tttgaggata atgatcaagc gaggatggac taacaccaat ctgtttcgat atatattgta
     2401 tgaccgaatc tgggatgctt ttgatatgag tgtatggcca accgggatac cgaagaacag
     2461 ctaattgaac agcaaatcct aaacggtttt cttccctcct tcgcttatta actatttcta
     2521 aatcccgttt ggaaaaagtg aagtaggtcc ccagtatcca ttcatcttca gggatttgca
     2581 taaaagcctg tctctgttcc ggtgtaagca attctctacc tctcgcaatt ttcattcagt
     2641 atcattccat ttctgtattt tcaatttatt agttcaatta tatatcaata gagtgtactc
     2701 tattgataca aatgtagtag actgataaaa tcatagttaa gagcgtctca taagacttgt
     2761 ctcaaaaatg aggtgatatt ttgcggaaaa tcggttatat tcgtgtcagt tcgactaacc
     2821 agaatccttc aagacaattt cagcagttga acgagatcgg aatggatatt atatatgaag
     2881 agaaagtttc aggagcaaca aaggatcgcg agcaacttca aaaagtgtta gacgatttac
     2941 aggaagatga catcatttat gttacagact taactcgaat cactcgtagt acacaagatc
     3001 tatttgaatt aatcgataac atacgagata aaaaggcaag tttaaaatca ctaaaagata
     3061 catggcttga tttatcagaa gataatccat acagccaatt cttaattact gtaatggctg
     3121 gtgttaacca attagagcga gatcttattc ggatgagaca acgtgaaggg attgaattgg
     3181 ctaagaaaga aggaaagttt aaaggtcgat taaagaagta tcataaaaat cacgcaggaa
     3241 tgaattatgc ggtaaagcta tataaagaag gaaatatgac tgtaaatcaa atttgtgaaa
     3301 ttactaatgt atctagggct tcattataca ggaaattatc agaagtgaat aattagccat
     3361 tctgtattcc gctaatgggc aatattttta aagaagaaaa ggaaactata aaatattaac
     3421 agcctcctag cgatgccgaa aagccctttg ataaaaaaag aatcatcatc ttaagaaatt
     3481 cttagtcatt tattatgtaa atgcttataa attcggccct ataatctgat aaattattaa
     3541 gggcaaactt atgtgaaagg gtgataacta tgagcgataa aatacttatt gtggatgatg
     3601 aacatgaaat tgccgatttg gttgaattat acttaaaaaa cgagaattat acggttttca
     3661 aatactatac cgccaaagaa gcattggaat gtatagacaa gtctgagatt gaccttgcca
     3721 tattggacat catgcttccc ggcacaagcg gccttactat ctgtcaaaaa ataagggaca
     3781 agcacaccta tccgattatc atgctgaccg ggaaagatac agaggtagat aaaattacag
     3841 ggttaacaat cggcgcggat gattatataa cgaagccctt tcgcccactg gagttaattg
     3901 ctcgggtaaa ggcccagttg cgccgataca aaaaattcag tggagtaaag gagcagaacg
     3961 aaaatgttat cgtccactcc ggccttgtca ttaatgttaa cacccatgag tgttatctga
     4021 acgagaagca gttatccctt actcccaccg agttttcaat actgcgaatc ctctgtgaaa
     4081 acaaggggaa tgtggttagc tccgagctgc tatttcatga gatatggggc gacgaatatt
     4141 tcagcaagag caacaacacc atcaccgtgc atatccggca tttgcgcgaa aaaatgaacg
     4201 acaccattga taatccgaaa tatataaaaa cggtatgggg ggttggttat aaaattgaaa
     4261 aataaaaaaa acgactattc caaactagaa cgaaaacttt acatgtatat cgttgcaatt
     4321 gttgtggtag caattgtatt cgtgttgtat attcgttcaa tgatccgagg gaaacttggg
     4381 gattggatct taagtatttt ggaaaacaaa tatgacttaa atcacctgga cgcgatgaaa
     4441 ttatatcaat attccatacg gaacaatata gatatcttta tttatgtggc gattgtcatt
     4501 agtattctta ttctatgtcg cgtcatgctt tcaaaattcg caaaatactt tgacgagata
     4561 aataccggca ttgatgtact tattcagaac gaagataaac aaattgagct ttctgcggaa
     4621 atggatgtta tggaacaaaa gctcaacaca ttaaaacgga ctctggaaaa gcgagagcag
     4681 gatgcaaagc tggccgaaca aagaaaaaat gacgttgtta tgtacttggc gcacgatatt
     4741 aaaacgcccc ttacatccat tatcggttat ttgagcctgc ttgacgaggc tccagacatg
     4801 ccggtagatc aaaaggcaaa gtatgtgcat atcacgttgg acaaagcgta tcgactcgaa
     4861 cagctaatcg acgagttttt tgagattaca cggtataacc tacaaacgat aacgctaaca
     4921 aaaacgcaca tagacctata ctatatgctg gtgcagatga ccgatgaatt ttatcctcag
     4981 ctttccgcac atggaaaaca ggcggttatt cacgcccccg aggatctgac cgtgtccggc
     5041 gaccctgata aactcgcgag agtctttaac aacattttga aaaacgccgc tgcatacagt
     5101 gaggataaca gcatcattga cattaccgcg ggcctctccg gggatgtggt gtcaatcgaa
     5161 ttcaagaaca ctggaagcat cccaaaagat aagctagctg ccatatttga aaagttctat
     5221 aggctggaca atgctcgttc ttccgatacg ggtggcgcgg gacttggatt ggcgattgca
     5281 aaagaaatta ttgttcagca tggagggcag atttacgcgg aaagcaatga taactatacg
     5341 acgtttaggg tagagcttcc agcgatgcca gacttggttg ataaaaggag gtcctaagag
     5401 atgtatataa ttttggctct ttgtcaaatg atgttggtaa agagaaatct
//
LOCUS       DAFEKH010000196         4863 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.guided.118, whole genome shotgun sequence.
ACCESSION   DAFEKH010000196
VERSION     DAFEKH010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4863
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.guided.118"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            362..1273
                     /locus_tag="LP386_003149"
     CDS             362..1273
                     /locus_tag="LP386_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HBL1920284.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            1426..1911
                     /gene="vanZ"
                     /locus_tag="LP386_003150"
     CDS             1426..1911
                     /gene="vanZ"
                     /locus_tag="LP386_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HBL1920285.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(2198..2527)
                     /locus_tag="LP386_003151"
     CDS             complement(2198..2527)
                     /locus_tag="LP386_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1920286.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCVLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            2832..3161
                     /locus_tag="LP386_003152"
     CDS             2832..3161
                     /locus_tag="LP386_003152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL1920287.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            3151..3438
                     /locus_tag="LP386_003153"
     CDS             3151..3438
                     /locus_tag="LP386_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBL1920288.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(3717..4280)
                     /locus_tag="LP386_003154"
     CDS             complement(3717..4280)
                     /locus_tag="LP386_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1920289.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
BASE COUNT         1706 a          733 c          838 g         1586 t
ORIGIN      
        1 atttgatagt agatttaaaa ctttgcaaca gaaccattga agatgtaagg cagagcgata
       61 ttgcggtcat tatctgcgtg cgctgcggca agatagcctg ataataagac tgatcgcata
      121 gaggggtggt atttcacacc gcccattgtc aacaggcagt tcagcctcgt taaattcagc
      181 atgggtatca cttatgaaaa ttcatctaca ttggtgataa tagtaaatcc agtagggcga
      241 aataattgac tgtaatttac ggggcaaaac ggcacaatct caaacgagat tgtgccgttt
      301 aaggggaaga ttctagaaat atttcatact tccaactata tagttaagga ggagactgaa
      361 aatgaagaag ttgttttttt tattgttatt gttattctta atatacttag gttatgacta
      421 cgttaatgaa gcactgtttt ctcaggaaaa agtcgaattt caaaattatg atcaaaatcc
      481 caaagaacat ttagaaaata gtgggacttc tgaaaatacc caagagaaaa caattacaga
      541 agaacaggtt tatcaaggaa atctgctatt aatcaatagt aaatatcctg ttcgccaaga
      601 aagtgtgaag tcagatatcg tgaatttatc taaacatgac gaattaataa atggatacgg
      661 gttgcttgat agtaatattt atatgtcaaa agaaatagca caaaaatttt cagagatggt
      721 caatgatgct gtaaagggtg gcgttagtca ttttattatt aatagtggct atcgagactt
      781 tgatgagcaa agtgtgcttt accaagaaat gggggctgag tatgccttac cagcaggtta
      841 tagtgagcat aattcaggtt tatcactaga tgtaggatca agcttgacga aaatggaacg
      901 agcccctgaa ggaaagtgga tagaagaaaa tgcttggaaa tacgggttca ttttacgtta
      961 tccagaggac aaaacagagt taacaggaat tcaatatgaa ccatggcata ttcgctatgt
     1021 tggtttacca catagtgcga ttatgaaaga aaagaatttc gttctcgagg aatatatgga
     1081 ttacctaaaa gaagaaaaaa ccatttctgt tagtgtaaat ggggaaaaat atgagatctt
     1141 ttattatcct gttactaaaa ataccaccat tcatgtgccg actaatcttc gttatgagat
     1201 atcaggaaac aatatagacg gtgtaattgt gacagtgttt cccggatcaa cacatactaa
     1261 ttcaaggagg taaggatggc ggaatgaaac caacgaaatt aatgaacagc attattgtac
     1321 tagcactttt ggggtaacgt tagcttttta atttaaaacc cacgttaact aggacattgc
     1381 tatactaatg atacaactta aacaaaagaa ttagaggaaa ttatattggg aaaaatatta
     1441 tctagaggat tgctagcttt atatttagtg acactaatct ggttagtgtt attcaaatta
     1501 caatacaata ttttatcagt atttaattat catcaaagaa gtcttaactt gactccattt
     1561 actgctactg ggaatttcag agagatgata gataatgtta taatctttat tccatttggc
     1621 ttgcttttga atgtcaattt taaagaaatc ggatttttac ctaagtttgc ttttgtactg
     1681 gttttaagtc ttacttttga aataattcaa tttatcttcg ctattggagc gacagacata
     1741 acagatgtaa ttacaaatac tgttggaggc tttcttggac tgaaattata tggtttaagc
     1801 aataagcata tgaatcaaaa aaaattagac agagttatta tttttgtagg tatacttttg
     1861 ctcgtattat tgctcgttta ccgtacccat ttaagaataa attacgtgta agatgtctaa
     1921 atcaagcaat ctgatctttc atacacataa agatattgaa tgaattggat tagatggaaa
     1981 acgggatgtg gggaaactcg cccgtaggtg tgaagtgagg ggaaaaccgg tgataaagta
     2041 aaaagcttac ctaacactat agtaacaaag aaagcccaat tatcaatttt agtgctgagg
     2101 aattggtctc tttaataaat ttccttaacg ttgtaaatcc gcattttcct gacggtaccc
     2161 ccaaactaag atttcataga tagattttct gataacttta aaaaacacga atagcggaaa
     2221 ggatgtcttc attcgctaaa gagtaataaa ctacttttcc atcttgacgt gattttgcca
     2281 ttccatgttt ttttaaaaaa cgtaaatggt gtgacgttgt agcgacacta gcagtaagta
     2341 tttctgctaa aacacagacg cacatttcct tataggtttc taaagcatag aaaattttaa
     2401 ttctagaaaa atcgctgaaa catttcccta acacaagtaa gtttgaaaaa tctttttgat
     2461 ccaatttatt ttttattcca tttacttttt ctttatgtac gacagtcact tggcaaactt
     2521 ttttcattca tctcacctca cattcaaacg attatttgaa tgaagtatac ctatttgatc
     2581 actcttttgt caatctacct taattccaat acactattat aagcaatttc atgtattgaa
     2641 gtaaacttac ttgcaagtgc gtttttgatt ccaagttaaa aacatattat tattctacat
     2701 aatttcctaa tcaaataaaa ctcctttgaa aattgttcta aaggagtttt attattttgt
     2761 atttctacta aaaatagcgt acaatgtaat tactaagtaa ttacgaaatg taaaataatg
     2821 gaggaaataa tatgattaca aaaacaagaa aacaaggaaa ttctattatg ttaacggtcc
     2881 ctaaagaatt cgatgtgccc aatggtgttg aagtagaagc taagcttgta gagaatggta
     2941 tcctttatga gtttgtagag cctaaaaaag aattttttga ttttagtgaa gatattttgg
     3001 ctgatattct ttcagaaggt tatagcaaac aagagatctt aaaagaattt agaaatagaa
     3061 aaaatgcgtt aacttctgca tttaaatcta ttgctgaaga tactgttgca aattctaaac
     3121 cgatgacaaa agaggagttg gcagcagaaa ttggcttatg agattctacc ttctaaacac
     3181 gtaataaagt atctaaaaaa attaaaagag aaaacattaa aagaacaatt tttaacgata
     3241 atttatgatg agatagcagt tcgtcctcat tcgggagaac aaaaaacggg tgatttatca
     3301 ggaatttggg ctattggatt caagtatgca ggtacgacat atcgcgttgc atatgaaatt
     3361 aaagataatg cagtgatacc tatcttacta tgtggaacgc atgaaaattt ttatgaacaa
     3421 ttaaaaaaga ttaggtaaga acccaatgtt tcaacttgag aggatagacg acactttaaa
     3481 agataatttt taacagctga gagttgtaat accctataat tttaaaccac taacctatat
     3541 atttatgaaa aatagaaaaa attaaaacgc attttaagcc tctttcaaat taaaagcttc
     3601 atccttatgc acaaagaggg cttaaaatgc gttattttat attgtttttt agtaataata
     3661 aaaaaatcac tctaattctc ccataaatat tatagattcc taaagattaa aatagattat
     3721 tccctattgt cttttaagta gcggtagagt gttgccttgc taataccagt catttccgta
     3781 atttctttta cgctataaac ctgactttta tacaatttta ctgctcgatc aacatctttc
     3841 tggttcactc gtggacggcc acctttacga cctctcgcac gtgcactttt caaaccttct
     3901 ttggtacgtt caacaattaa atcacgttcg aactgactaa atgcttggaa gacagtcatc
     3961 attaagcgtc cgtgaggcgt gctggtatcg aagttttctt tcaagctcac cagcttaaca
     4021 tggtgttctt caaaataggt aacaaggtca atcaaatcct ttgtactacg acccaatcga
     4081 gaaaaacttt ctacaattac cgtatctccc ggacgaattt tatcttttaa acgatttagt
     4141 tggggacgaa ccgctttggt tcccgtcatt ttctcagtta ggatttcatt acaattttgt
     4201 tcattgagta agtctaattg acgatttagt tcttgtgaac gtgtactcac tcgggcataa
     4261 ccataaatgt atccactcat gcttttcttc ctttcgtact ttaattctgg cttgattgta
     4321 tcataaaagg gagttataga tacatagtta atgcaacaag ttatgataca aaatatgacc
     4381 tcttttattt aataaaagag gtcatttcat tttgtctgat aatcgattgt ttttgatacg
     4441 agtgtgtata cgaaataaac aaaaaaatct taagtaaatt tctagatacc taatttaatc
     4501 ctaactagtg tatcctaaag ttaataacga gtttatcaca atgaaaatta taaaatgctc
     4561 ccatattaga tataacatgc aatatttgaa ttagaactac aaaatttatt cgttttataa
     4621 agtaaataat gttgagatac taaggaatag aatattataa ggaattgagc tgaatgtatt
     4681 ggataaaaaa agaataactt tattagagat ggactataaa aatgctcgta attttcttct
     4741 gaagtctgaa agctatttga atgctcagct accagaatat attagttttg acgaaacttt
     4801 aaaatctgct aaaaaagttt taacttcgcc gtttgtataa ttaagcgaga caaataaaaa
     4861 agc
//
LOCUS       DAFEKH010000197         3816 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.guided.128, whole genome shotgun sequence.
ACCESSION   DAFEKH010000197
VERSION     DAFEKH010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3816
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.guided.128"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            22..1941
                     /gene="tet(M)"
                     /locus_tag="LP386_003155"
     CDS             22..1941
                     /gene="tet(M)"
                     /locus_tag="LP386_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HBL1920290.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            2039..3412
                     /gene="tet(L)"
                     /locus_tag="LP386_003156"
     CDS             2039..3412
                     /gene="tet(L)"
                     /locus_tag="LP386_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HBL1920291.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
     gene            complement(3461..3661)
                     /locus_tag="LP386_003157"
     CDS             complement(3461..3661)
                     /locus_tag="LP386_003157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1920292.1"
                     /translation="MPIFILSVLSSLPKARLSKNKIFIVFRFSSVTDKTTQNKKDTRE
                     VSRIFYSAIAPFNGTKRFEFLL"
BASE COUNT         1209 a          584 c          782 g         1241 t
ORIGIN      
        1 ttttgaatgg aggaaaatca catgaaaatt attaatattg gagttttagc tcatgttgat
       61 gcgggaaaaa ctaccttaac agaaagctta ttatataaca gtggagcgat tacagaatta
      121 ggaagcgtgg acaaaggtac aacgaggacg gataatacgc ttttagaacg tcagagagga
      181 attacaattc agacaggaat aacctctttt cagtgggaaa atacgaaggt gaacatcata
      241 gacacgccag gacatatgga tttcttagca gaagtatatc gttcattatc agttttagat
      301 ggggcaattc tactgatttc tgcaaaagat ggcgtacaag cacaaactcg tatattattt
      361 catgcactta ggaaaatggg gattcccaca atctttttta tcaataagat tgaccaaaat
      421 ggaattgatt tatcaacggt ttatcaggat attaaagaga aactttctgc cgaaattgta
      481 atcaaacaga aggtagaact gtatcctaat atgtgtgtga cgaactttac cgaatctgaa
      541 caatgggata cggtaataga gggaaacgat gaccttttag agaaatatat gtccggtaaa
      601 tcattagaag cattggaact cgaacaagag gaaagcataa gatttcagaa ttgctccttg
      661 taccctgttt atcatggaag cgcaaaaagc aacataggga ttgagcagct tatagaagtg
      721 ataacgaata aattttattc atcaacatac agaaagaagt ctgaactttg cggaaatgtc
      781 ttcaaaattg aatattcgga agaaagacaa cgtcttgcat atgtacgcct ttatggcgga
      841 atcctgcatt tgcgggattc ggttagaata tcggaaaagg aaaaaataaa aattacagaa
      901 atgtatactt caataaatgg tgaattatgt aaaattgata aggcttattc cggggaaatt
      961 gttattttgc aaaatgagtt tttgaagcta aatagtgttc ttggagatac aaagctattg
     1021 ccacagagag agagaattga aaatccgctc cctctgctgc aaacaactgt tgaaccgagc
     1081 aaacctcaac aaagggaaat gttacttgat gcacttttag aaatctccga cagtgacccg
     1141 cttctacaat attatgtgga ttctacgaca catgaaatta tactttcttt cttagggaaa
     1201 gtacaaatgg aagtgattag tgcactgttg caagaaaagt atcatgtgga gatagaacta
     1261 aaagagccta cagtcattta tatggagaga ccgttaaaaa atgcagaata taccattcac
     1321 atcgaagtgc cgccaaatcc tttctgggct tccattggtt tatctgtatc accgcttccg
     1381 ttgggaagtg gaatgcagta tgagagctcg gtttctcttg gatacttaaa tcaatcattt
     1441 caaaatgcag ttatggaagg gatacgctat ggttgcgaac aaggattata tggttggaat
     1501 gtgacggatt gtaaaatctg ttttaagtat ggcttatact atagccctgt tagtacccca
     1561 gcagattttc ggatgcttgc tcctattgta ttggaacaag tcttaaaaaa agctggaaca
     1621 gaattgttag agccatatct tagttttaaa atttatgcgc cacaggaata tctttcacga
     1681 gcatacaacg atgctcctaa atattgtgcg aacatcgtag acactcaatt gaaaaataat
     1741 gaggtcattc ttagtggaga aatccctgct cggtgtattc aagaatatcg tagtgattta
     1801 actttcttta caaatggacg tagtgtttgt ttaacagagt taaaagggta ccatgttact
     1861 accggtgaac ctgtttgcca gccccgtcgt ccaaatagtc ggatagataa agtacgatat
     1921 atgttcaata aaataactta gtgtatttta tgttgttata taaatatggt ttcttgttaa
     1981 ataagatgaa atatttttta ataaagattt gaattaaagt gtaaaggagg aattaattat
     2041 gaagtgtaat gaatgtaaca gggttaaata caaccaaatt ttaatttggc tttgcgtttt
     2101 atcttttttt agcgtattaa atgaaatggt tttgaacgtc tcattacctg atattgcaaa
     2161 tgattttaat aaaccacctg cgagtacaaa ctgggtgaac acagccttta tgttaacctt
     2221 ttccattgga acagctgtat atggaaagct atctgatcaa ttaggcatca aaaggttact
     2281 cctatttgga attataataa attgtttcgg gtcggtaatt gggtttgttg gccattcttt
     2341 cttttcctta cttattatgg ctcgttttat tcaaggggct ggtgcagctg catttccagc
     2401 actcgtaatg gttgtagttg cgcgctatat tccaaaggaa aataggggta aagcatttgg
     2461 tcttattgga tcgatagtag ccatgggaga aggagtcggt ccagcgattg gtggaatgat
     2521 agcccattat attcattggt cctatcttct actcattcct atgataacaa ttatcactgt
     2581 tccgtttctt atgaaattat taaagaaaga agtaaggata aaaggtcatt ttgatatcaa
     2641 aggaattata ctaatgtctg taggcattgt attttttatg ttgtttacaa catcatatag
     2701 catttctttt cttatcgtta gcgtgctgtc attcctgata tttgtaaaac atatcaggaa
     2761 agtaacagat ccttttgttg atcccggatt agggaaaaat atacctttta tgattggagt
     2821 tctttgtggg ggaattatat ttggaacagt agcagggttt gtctctatgg ttccttatat
     2881 gatgaaagat gttcaccagc taagtactgc cgaaatcgga agtgtaatta ttttccctgg
     2941 aacaatgagt gtcattattt tcggctacat tggtgggata cttgttgata gaagaggtcc
     3001 tttatacgtg ttaaacatcg gagttacatt tctttctgtt agctttttaa ctgcttcctt
     3061 tcttttagaa acaacatcat ggttcatgac aattataatc gtatttgttt taggtgggct
     3121 ttcgttcacc aaaacagtta tatcaacaat tgtttcaagt agcttgaaac agcaggaagc
     3181 tggtgctgga atgagtttgc ttaactttac cagcttttta tcagagggaa caggtattgc
     3241 aattgtaggt ggtttattat ccataccctt acttgatcaa aggttgttac ctatggaagt
     3301 tgatcagtca acttatctgt atagtaattt gttattactt ttttcaggaa tcattgtcat
     3361 tagttggctg gttaccttga atgtatataa acattctcaa agggatttct aaatcgttaa
     3421 gggatcaact ttgggagaga gttcaaaatt gatccttttt ttataacagg aattcaaatc
     3481 tttttgttcc attaaagggc gcgattgctg aataaaagat acgagagacc tctcttgtat
     3541 cttttttatt ttgagtggtt ttgtccgtta cactagaaaa ccgaaagaca ataaaaattt
     3601 tattcttgct gagtctggct ttcggtaagc tagacaaaac ggacaaaata aaaattggca
     3661 agggtttaaa ggtggagatt ttttgagtga tcttctcaaa aaatactacc tgtcccttgc
     3721 tgatttttaa acgagcacga gagcaaaacc cccctttgct gaggtggcag agggcaggtt
     3781 tttttgtttc ttttttctcg taaaaaaaag aaaggt
//
LOCUS       DAFEKH010000198         3631 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.guided.130, whole genome shotgun sequence.
ACCESSION   DAFEKH010000198
VERSION     DAFEKH010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3631
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.guided.130"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            121..1188
                     /gene="rlmN"
                     /locus_tag="LP386_003158"
     CDS             121..1188
                     /gene="rlmN"
                     /locus_tag="LP386_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBL1920293.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(1381..2484)
                     /locus_tag="LP386_003159"
     CDS             complement(1381..2484)
                     /locus_tag="LP386_003159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBL1920294.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            3037..3585
                     /gene="aac(6')"
                     /locus_tag="LP386_003160"
     CDS             3037..3585
                     /gene="aac(6')"
                     /locus_tag="LP386_003160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBL1920295.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         1189 a          618 c          732 g         1092 t
ORIGIN      
        1 cttgtctttt tagtttttgt gagattaaag ttctattcga tttatttgtg aagtattgca
       61 ttaaggaaat gaatcatgta tagtatgtag cgaaactttg agaaaaagag ggaaaatact
      121 ttggaaaaac agtccattta tggcttgacg aatgaagaat taatcaattg gtttatagaa
      181 aacggcgaga aaaaattccg agctgcccaa gtttgggaat ggttgtatca aaaacgtgta
      241 agtaatttca cagaaatgac gaatctatcg aaacaattga tcgaaaaatt atcggagcat
      301 tttatcatca atcctctaaa acagatggtc gtccaagaag cttcggatgg tacagtaaaa
      361 tatttgtttg aactccctga taaaaacatg attgagactg tactgatgag acaagaatat
      421 ggcttgtcag tttgtgtgac gacacaagta ggatgtaata tcggctgtac gttttgtgca
      481 agcgggctgc tcaaaaagaa ccgtgatctg actgctggag aaattgttgc acagatcatg
      541 atggtccaac attattttga tgagcgcaat cttggcgaac gcgtttcaca tgtcgttgta
      601 atggggatcg gtgagccatt tgataattac gacaatgtaa tggacttttt gcatatcatc
      661 aatgatgcca aaggattggc aattggtgct cggcacatta cagtttccac tagtggatta
      721 gcacacaaaa tcaaggaatt cgctaataac ggcttgcaag tcaatctggc tatttccttg
      781 cacgcgccga ataatgaggt gcgaacatcg atcatgcgga tcaaccgaag tttcccaatt
      841 gagaaattga tggaagctgt ggatgagtat ttagagaaaa caaaccgtcg aatcacgttt
      901 gaatatatca tgttgaatca agtaaatgat agaccagagc atgcgcaaca attagcagat
      961 ctattaaaag ataagaaaaa attagcatat gtcaacttga ttccatataa tccagtcagt
     1021 gaacatgatc aatattctcg cagtccaaaa gctgatgtat tgagatttta tgatgtattg
     1081 aagaaaaacg gcgtaaactg tgtgatacgt aaagaacatg gtacagatat tgatgcagct
     1141 tgcggacaat tgcgaagcaa gcaaatgaaa aaaacagttg ccaaataatc gtatcctact
     1201 cgttttttca attaccataa aaggagcagt tttcttaatt aaggaactgt tcaacttaaa
     1261 taagagaaaa gattctatag cgaaagctat aaagcttttt ttgacaagaa aaaccctcat
     1321 caagcaaaga aatgtcctca atttgatgac agcctgcttg atgggggttt tagcaattat
     1381 ttaactgatt ttcttatatc cttgctggct ttcttgtgta gcatgataag tttctacgtc
     1441 aagaatggcc tgtttaaatt tttctcgggt gatttcataa ggcacatgtt taatatcatt
     1501 tgttgccatg gctttatcta agattgcttc taaatcggtc gtgacattga gattcatgtc
     1561 ggttaacgat actggaagtt ggttcttttt cataaacaca tagattttat caaacaaatc
     1621 gaactgctga tccatcatca ataaggtcag tacaccataa ctgacagatg ctccgtgaag
     1681 gtatccctcc attttttcta gaacagtcgt accgtaatag aatgagtgtg ccatagcaga
     1741 attatagtta ttgttaacta aaacagaaac caatccggta gtaacaatga tatccgaaac
     1801 gacttgttca attgcatatg agggacgatc gtcggcacta tctttcaatg cttgcgtacc
     1861 ataagtcaag agacgatcaa tgcacatttt tccgatttgg attcctaatc tatccgtgta
     1921 gcctagatca tcgccacgag cagaaaaagt agattcgact tctttggata aagcatcgcc
     1981 aatacctgcc cataagtatt tatcaggtgc ttcggcaata attgctgtat caatgaaggt
     2041 gtgtacaggt ggttttgaag gaaagaagag tccgtccatt acgccttctt cgttatagat
     2101 gacacatacc gcagtgacgg gcgaacagtt cgaaccaata gtgggaaagg tgaagactgg
     2161 tttagctagt ttttcaccaa tgacttttac agtatcgcaa gcacggccac caccgactgc
     2221 aaacaggacg tctgcttttt ggacactttc atgctggatc aactgttcaa tatttccata
     2281 agttgaatta cccccgtacc agagactggc gacaacctct atttcctgtg tcaaagctac
     2341 ttttattttg ttttctgcct ttgaaagtgc agtcttccct ccaatcagca ctacttttgt
     2401 cccatattct ttgacgattc catttgcttt ttcatacgca tctgttccaa tggtataatt
     2461 tggtaagaaa acactttgac tcatattcat ttccttcttt cttcgttgaa acgggttaaa
     2521 attttaaaga gtgatcgatc tgactgcggc tgtagatgga gtagaggtga acctaagaca
     2581 ggataagtga tgaataaggt ggcatgaaca ccttgaaatc atcaataagt atcctaaaaa
     2641 cgaacaagta caaaaacatt gaaaacgaca ataatgaatt tttgttcctc ttagtatttc
     2701 taccgattcc ctttgctttt ttgtaattat ctaaaaattc taaaaattaa gattattata
     2761 tgaaaacagg ttttatttgt caattcataa ttggtttttt ttaaagcaaa agataatcta
     2821 tatcatgatg aacaaacaga gttttttcct ccaattgatg gctttcctga tctttcctat
     2881 tttgaataaa gtgtttctgt ataatttttt tattttataa gtaagataaa taatgaaaga
     2941 atagagatac tgattggtag ctaaagattt ttgagcgaga acatttcgtt ttttcaaaag
     3001 gactgttaga ataagcaaga acaaggggga agacgtatga taatcagtga atttgaccgt
     3061 aataatccag tattgaaaga tcagctttct gatttactga gactgacttg gccggaagaa
     3121 tatggagaca gctcggcaga agaagtagaa gaaatgatga atccagaacg aatcgcggta
     3181 gcagcggtag accaagatga gttagtagga tttattggtg caatccctca atacggtatc
     3241 acaggttggg aattgcatcc attagttgta gaaagctccc gacgaaagaa ccaaataggt
     3301 actcgattag tcaattactt agaaaaagaa gtagcttcca gaggaggaat cacgatttat
     3361 ttaggtacgg atgatttaga ccatggaaca acgttaagtc aaacggacct gtatgagcat
     3421 acatttgata aagtggcttc catccagaac cttcgtgaac atccgtatga attctatgaa
     3481 aaattaggtt ataaaatcgt aggtgtctta ccaaatgcaa atggctggga caaaccggat
     3541 atttggatgg caaaaacgat tattcctcga ccaaattctc aataataaaa agaggttgtg
     3601 acagaagtaa tcagcttcaa gaaataagaa g
//
LOCUS       DAFEKH010000199         2924 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.guided.137, whole genome shotgun sequence.
ACCESSION   DAFEKH010000199
VERSION     DAFEKH010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2924
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.guided.137"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            245..1213
                     /locus_tag="LP386_003161"
     CDS             245..1213
                     /locus_tag="LP386_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HBL1920296.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1206..2237
                     /gene="vanA"
                     /locus_tag="LP386_003162"
     CDS             1206..2237
                     /gene="vanA"
                     /locus_tag="LP386_003162"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HBL1920297.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2243..2851
                     /locus_tag="LP386_003163"
     CDS             2243..2851
                     /locus_tag="LP386_003163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HBL1920298.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT          870 a          564 c          705 g          785 t
ORIGIN      
        1 atgctggtgt catccaccaa catcaaaaag tatagagcca taatttttta ggaaaatctc
       61 aaggttatct ttactttttc ttaggaaatt aacaatttaa tattaagaaa cggctcgttc
      121 ttacacggta gacttaatac cgtaagaacg agccgttttc gttcttcaga gaaagatttg
      181 acaagattac cattggcatc cccgttttat ttggtgcctt tcacagaaag ggttggtctt
      241 aattatgaat aacatcggca ttactgttta tggatgtgag caggatgagg cagatgcatt
      301 ccatgctctt tcgcctcgct ttggcgttat ggcaacgata attaacgcca acgtgtcgga
      361 atccaacgcc aaatccgcgc ctttcaatca atgtatcagt gtgggacata aatcagagat
      421 ttccgcctct attcttcttg cgctgaagag agccggtgtg aaatatattt ctacccgaag
      481 catcggctgc aatcatatag atacaactgc tgctaagaga atgggcatca ctgtcgacaa
      541 tgtggcgtac tcgccggata gcgttgccga ttatactatg atgctaattc ttatggcagt
      601 acgcaacgta aaatcgattg tgcgctctgt ggaaaaacat gatttcaggt tggacagcga
      661 ccgtggcaag gtactcagcg acatgacagt tggtgtggtg ggaacgggcc agataggcaa
      721 agcggttatt gagcggctgc gaggatttgg atgtaaagtg ttggcttata gtcgcagccg
      781 aagtatagag gtaaactatg taccgtttga tgagttgctg caaaatagcg atatcgttac
      841 gcttcatgtg ccgctcaata cggatacgca ctatattatc agccacgaac aaatacagag
      901 aatgaagcaa ggagcatttc ttatcaatac tgggcgcggt ccacttgtag atacctatga
      961 gttggttaaa gcattagaaa acgggaaact gggcggtgcc gcattggatg tattggaagg
     1021 agaggaagag tttttctact ctgattgcac ccaaaaacca attgataatc aatttttact
     1081 taaacttcaa agaatgccta acgtgataat cacaccgcat acggcctatt ataccgagca
     1141 agcgttgcgt gataccgttg aaaaaaccat taaaaactgt ttggattttg aaaggagaca
     1201 ggagcatgaa tagaataaaa gttgcaatac tgtttggggg ttgctcagag gagcatgacg
     1261 tatcggtaaa atctgcaata gagatagccg ctaacattaa taaagaaaaa tacgagccgt
     1321 tatacattgg aattacgaaa tctggtgtat ggaaaatgtg cgaaaaacct tgcgcggaat
     1381 gggaaaacga caattgctat tcagctgtac tctcgccgga taaaaaaatg cacggattac
     1441 ttgttaaaaa gaaccatgaa tatgaaatca accatgttga tgtagcattt tcagctttgc
     1501 atggcaagtc aggtgaagat ggatccatac aaggtctgtt tgaattgtcc ggtatccctt
     1561 ttgtaggctg cgatattcaa agctcagcaa tttgtatgga caaatcgttg acatacatcg
     1621 ttgcgaaaaa tgctgggata gctactcccg ccttttgggt tattaataaa gatgataggc
     1681 cggtggcagc tacgtttacc tatcctgttt ttgttaagcc ggcgcgttca ggctcatcct
     1741 tcggtgtgaa aaaagtcaat agcgcggacg aattggacta cgcaattgaa tcggcaagac
     1801 aatatgacag caaaatctta attgagcagg ctgtttcggg ctgtgaggtc ggttgtgcgg
     1861 tattgggaaa cagtgccgcg ttagctgttg gcgaggtgga ccaaatcagg ctgcagtacg
     1921 gaatctttcg tattcatcag gaagtcgagc cggaaaaagg ctctgaaaac gcagttataa
     1981 ccgttcccgc agacctttca gcagaggagc gaggacggat acaggaaacg gcaaaaaaaa
     2041 tatataaagc gctcggctgt agaggtctag cccgtgtgga tatgttttta caagataacg
     2101 gccgcattgt actgaacgaa gtcaatactc tgcccggttt cacgtcatac agtcgttatc
     2161 cccgtatgat ggccgctgca ggtattgcac ttcccgaact gattgaccgc ttgatcgtat
     2221 tagcgttaaa ggggtgataa gcatggaaat aggatttact tttttagatg aaatagtaca
     2281 cggtgttcgt tgggacgcta aatatgccac ttgggataat ttcaccggaa aaccggttga
     2341 cggttatgaa gtaaatcgca ttgtagggac atacgagttg gctgaatcgc ttttgaaggc
     2401 aaaagaactg gctgctaccc aagggtacgg attgcttcta tgggacggtt accgtcctaa
     2461 tcgtgctgta aactgtttta tgcaatgggc tgcacagccg gaaaataacc tgacaaagga
     2521 aagttattat cccaatattg accgaactga gatgatttca aaaggatacg tggcttcaaa
     2581 atcaagccat agccgcggca gtgccattga tcttacgctt tatcgattag acacgggtga
     2641 gcttgtacca atggggagcc gatttgattt tatggatgaa cgctctcatc atgcggcaaa
     2701 tggaatatca tgcaatgaag cgcaaaatcg cagacgtttg cgctccatca tggaaaacag
     2761 tgggtttgaa gcatatagcc tcgaatggtg gcactatgta ttaagagacg aaccataccc
     2821 caatagctat tttgatttcc ccgttaaata aacttttaac cgttgcacgg acaaactata
     2881 taagcggttc tgttgcaaag ttttaaataa agaataaaat ccct
//
LOCUS       DAFEKH010000200         2534 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.guided.146, whole genome shotgun sequence.
ACCESSION   DAFEKH010000200
VERSION     DAFEKH010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.guided.146"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            38..244
                     /locus_tag="LP386_003164"
                     /pseudo
     CDS             38..244
                     /locus_tag="LP386_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
     gene            complement(316..813)
                     /gene="dfrG"
                     /locus_tag="LP386_003165"
     CDS             complement(316..813)
                     /gene="dfrG"
                     /locus_tag="LP386_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HBL1920299.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            1175..2215
                     /locus_tag="LP386_003166"
     CDS             1175..2215
                     /locus_tag="LP386_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBL1920300.1"
                     /translation="MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRK
                     KIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQ
                     MEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLP
                     LGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVS
                     TPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIVNTQ
                     LKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRLNSR
                     IDKVRYMFNKIT"
     gene            2313..2501
                     /locus_tag="LP386_003167"
     CDS             2313..2501
                     /locus_tag="LP386_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HBL1920301.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
BASE COUNT          842 a          434 c          407 g          851 t
ORIGIN      
        1 tccgccgttt tcctacattt tatagccgcc atttacatta acaacagctc gtggtgataa
       61 gaagagctat atttacgcta acttcaatcc gaagtatgct caatttgcga ttacaattct
      121 aagaacttac tacaactttt gtcgcccttt taaatcagcg gataaaaagg ttttgacacc
      181 tgctcaaaga ttagggatta cagataaaca atttgattgg aaagatataa tttatttcaa
      241 atgacaaaaa gagcttggag taatcccaag ctcttgtgct ttatctttac tgttcttctt
      301 caattaacgc acccgttaac tcaataagtt ttttctttca tatacatgaa aatagtagtt
      361 atacggattt ttatcattct ttatcccttt ttgggcaaat acctcattcc attcctcata
      421 attcacttct ggaaaaaaag tatctccttc gaattcatga tgtatttttg tgatgtacat
      481 tttctcaaca taagggaaaa acaaattata aatctgttct cctccgaaaa taaaaatttc
      541 ttcttcgttt ttacataact caaaaacatc ttctattgaa tgaacaattt cacaaccatt
      601 aaaggtaaac cccttatctc tcgtcagaat aatatttctt ctgtcaggta aggctcttcc
      661 gattgattca aggttcttcc tacctaatat tatcggatgt ccctttgtag tatttttaac
      721 atattcccag tccttgggaa tcctccaagg aatgtcattc tctttgccaa tcactctatt
      781 cttatccatc gcagcaatca aagaaacttt catttataac acagcctttt taactaattt
      841 accatctaat ttcttatttc tatcaaaaaa ccttttctca ttatcctgcc cgttagttga
      901 ataagcaatt ttttctataa gttatattat cataatacca caaaatcaca aattttcatt
      961 caattatcat tttcaattgc attttataaa tcattttgta tgtaatttgg tatgtaagtt
     1021 aaaatgaaaa aagtagtcca ttttgaagta cattttgtca ttttgtactc caaaactgaa
     1081 ctacttactt gcatatatac gcctttatag tggagtacta catttacgag attcggttag
     1141 agtatcagaa aaagaaaaaa taaaagttac agaaatgtat acttcaataa atggtgaatt
     1201 atgtaagatt gatagagctt attctggaga aattgttatt ttgcaaaatg agtttttgaa
     1261 gttaaatagt gttcttggag atacaaaact attgccacag agaaaaaaga ttgaaaatcc
     1321 gcaccctcta ctacaaacaa ctgttgaacc gagtaaacct gaacagagag aaatgttgct
     1381 tgatgccctt ttggaaatct cagatagtga tccgcttcta cgatattacg tggattctac
     1441 gacacatgaa attatacttt ctttcttagg gaaagtacaa atggaagtga ttagtgcact
     1501 gttgcaagaa aagtatcatg tggagataga actaaaagag cctacagtca tttatatgga
     1561 gagaccgtta aaaaatgcag aatataccat tcacatcgaa gtgccgccaa atcctttctg
     1621 ggcttccatt ggtttatctg tatcaccgct tccgttggga agtggaatgc agtatgagag
     1681 ctcggtttct cttggatact taaatcaatc atttcaaaat gcagttatgg aagggatacg
     1741 ctatggttgc gaacaaggat tatatggttg gaatgtgacg gattgtaaaa tctgttttaa
     1801 gtacggttta tactatagcc ctgttagtac tccagcagat tttcggatgc ttactcctat
     1861 tgtactggag caagccttta gaaaagctgg aacagaattg ttagagccat atcttagttt
     1921 taaagtttat gcaccacagg aatatctttc acgggcatat aacgatgctc ccaaatattg
     1981 tgcaaatatc gtaaatactc aactgaaaaa taatgaggtc attattattg gagaaattcc
     2041 tgctcgatgt attcaagatt atcgcaatga tttaactttt tttacaaatg ggcttagtgt
     2101 ttgtttagca gagctaaaag gatatcaggt taccactggc gaacctgttt gccagacccg
     2161 tcgtctaaat agtcggatag ataaagtaag atatatgttc aataaaataa cttagtgcgt
     2221 tttatgttgt tatataaata tggtttctta ttaaataaga tgaaatattc tttaatatag
     2281 atttgaatta aagtggaaag gaggagattg ttattataaa ctacaagtgg atattgtgtc
     2341 ctatttgtgg aaataaaaca agactacgaa tacgagtgga tactatactt aaaaatttcc
     2401 ctttatactg ccccaaatgt aagaacgaaa ctttaattaa tgttcaaaaa atgaatataa
     2461 taacaatcaa agagccagac gccaagacgc agagccgata atttgagaaa tgaaactctc
     2521 atcttatcgg ctct
//
LOCUS       DAFEKH010000201         1650 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.guided.160, whole genome shotgun sequence.
ACCESSION   DAFEKH010000201
VERSION     DAFEKH010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1650
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.guided.160"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            <1..1348
                     /locus_tag="LP386_003168"
     CDS             <1..1348
                     /locus_tag="LP386_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase
                     APH(2'')-Ia"
                     /protein_id="HBL1920302.1"
                     /translation="DFILYLKLCNRTESLKKHYTEPWEDEVFRVIIEYNNVPIGYGQI
                     YKMYDELYTDYHYPKTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAV
                     ILDPHKNNPRAIRAYQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKY
                     LIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNT
                     NLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLR
                     QMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFE
                     GKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGE
                     DILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD"
     gene            complement(1478..>1650)
                     /locus_tag="LP386_003169"
     CDS             complement(1478..>1650)
                     /locus_tag="LP386_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1920303.1"
                     /translation="KSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEW
                     IYSSRKYINFDK"
BASE COUNT          671 a          148 c          278 g          553 t
ORIGIN      
        1 ggattttatt ctttatttaa aactttgcaa cagaaccgaa tcattaaaaa aacattatac
       61 agagccttgg gaagatgaag tttttagagt aattattgaa tataacaatg ttcctattgg
      121 atatggacaa atatataaaa tgtatgatga gttatatact gattatcatt atccaaaaac
      181 tgatgagata gtctatggta tggatcaatt tataggagag ccaaattatt ggagtaaagg
      241 aattggtaca agatatatta aattgatttt tgaatttttg aaaaaagaaa gaaatgctaa
      301 tgcagttatt ttagaccctc ataaaaataa tccaagagca ataagggcat accaaaaatc
      361 tggttttaga attattgaag atttgccaga acatgaatta cacgagggca aaaaagaaga
      421 ttgttattta atggaatata gatatgatga taatgccaca aatgttaagg caatgaaata
      481 tttaattgag cattactttg ataatttcaa agtagatagt attgaaataa tcggtagtgg
      541 ttatgatagt gtggcatatt tagttaataa tgaatacatt tttaaaacaa aatttagtac
      601 taataagaaa aaaggttatg caaaagaaaa agcaatatat aattttttaa atacaaattt
      661 agaaactaat gtaaaaattc ctaatattga atattcgtat attagtgatg aattatctat
      721 actaggttat aaagaaatta aaggaacttt tttaacacca gaaatttatt ctactatgtc
      781 agaagaagaa caaaatttgt taaaacgaga tattgccagt tttttaagac aaatgcacgg
      841 tttagattat acagatatta gtgaatgtac tattgataat aaacaaaatg tattagaaga
      901 gtatatattg ttgcgtgaaa ctatttataa tgatttaact gatatagaaa aagattatat
      961 agaaagtttt atggaaagac taaatgcaac aacagttttt gagggtaaaa agtgtttatg
     1021 ccataatgat tttagttgta atcatctatt gttagatggc aataatagat taactggaat
     1081 aattgatttt ggagattctg gaattataga tgaatattgt gattttatat acttacttga
     1141 agatagtgaa gaagaaatag gaacaaattt tggagaagat atattaagaa tgtatggaaa
     1201 tatagatatt gagaaagcaa aagaatatca agatatagtt gaagaatatt atcctattga
     1261 aactattgtt tatggaatta aaaatattaa acaggaattt atcgaaaatg gtagaaaaga
     1321 aatttataaa aggacttata aagattgatt atataatata tgaaaagcta ttataaaaga
     1381 cattagtatt aaatagttta aaaaaatgaa aaataataaa ggaagtgagt caagtccaga
     1441 ctcctgtgta aaatgctata caatgttttt accatttcta cttatcaaaa ttgatgtatt
     1501 ttcttgaaga ataaatccat tcatcatgta ggtccataag aacggctcca attaagcgat
     1561 tggctgatgt ttgattgggg aagatgcgaa taatcttttc tcttctgcgt acttcttgat
     1621 tcagtcgttc aattagattg gtactcttta
//
LOCUS       DAFEKH010000202         1500 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR16388_1
            SAMN20573922-rid13346563.guided.165, whole genome shotgun sequence.
ACCESSION   DAFEKH010000202
VERSION     DAFEKH010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20573922
            Sequence Read Archive: SRR16917338
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177061.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177061.1
            Genome Coverage       :: 181x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 11:22:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,172
            CDSs (total)                      :: 3,105
            Genes (coding)                    :: 3,030
            CDSs (with protein)               :: 3,030
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 4, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 31 of 75
            Pseudo Genes (internal stop)      :: 15 of 75
            Pseudo Genes (multiple problems)  :: 7 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1500
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20573922-rid13346563.guided.165"
                     /isolate="PR16388_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-07"
                     /collected_by="University of Michigan"
     gene            109..192
                     /locus_tag="LP386_003170"
     CDS             109..192
                     /locus_tag="LP386_003170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HBL1920304.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            317..1054
                     /gene="erm(B)"
                     /locus_tag="LP386_003171"
     CDS             317..1054
                     /gene="erm(B)"
                     /locus_tag="LP386_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBL1920305.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            1224..1484
                     /locus_tag="LP386_003172"
                     /pseudo
     CDS             1224..1484
                     /locus_tag="LP386_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
BASE COUNT          568 a          237 c          253 g          442 t
ORIGIN      
        1 ttatttgata gtagatttaa aactttgcaa cagaaccatt ttgtgtataa taggaattga
       61 agttaaatta gatgctaaaa atttgtaatt aagaaggagg gattcgtcat gttggtattc
      121 caaatgcgta atgtagataa aacatctact gttttgaaac agactaaaaa cagtgattac
      181 gcagataaat aaatacgtta gattaattcc taccagtgac taatcttatg actttttaaa
      241 cagataacta aaattacaaa caaatcgttt aacttctgta tttatttaca gatgtaataa
      301 cttcaggagt gattacatga acaaaaatat aaaatattct caaaactttt taacgagtga
      361 aaaagtactc aaccaaataa taaaacaatt gaatttaaaa gaaaccgata ccgtttacga
      421 aattggaaca ggtaaagggc atttaacgac gaaactggct aaaataagta aacaggtaac
      481 gtctattgaa ttagacagtc atctattcaa cttatcgtca gaaaaattaa aactgaacat
      541 tcgtgtcact ttaattcacc aagatattct acagtttcaa ttccctaaca aacagaggta
      601 taaaattgtt gggagtattc cttaccattt aagcacacaa attattaaaa aagtggtttt
      661 tgaaagccat gcgtctgaca tctatctgat tgttgaagaa ggattctaca agcgtacctt
      721 ggatattcac cgaacactag ggttgctctt gcacactcaa gtctcgattc agcaattgct
      781 taagctgcca gcggaatgct ttcatcctaa accaaaagta aacagtgtct taataaaact
      841 tacccgccat accacagatg ttccagataa atattggaag ctatatacgt actttgtttc
      901 aaaatgggtc aatcgagaat atcgtcaact gtttactaaa aatcagtttc atcaagcaat
      961 gaaacacgcc aaagtaaaca atttaagtac cgttacttat gagcaagtat tgtctatttt
     1021 taatagttat ctattattta acgggaggaa ataattctat gagtcgcttt tttaaatttg
     1081 gaaagttaca cgttactaaa gggaatggag ataaattatt agatatacta ctgacagctt
     1141 ccaagaagct aaagaggtcc ctagcgccta cggggaattt gtatcgataa ggggtacaaa
     1201 ttcccactaa gcgctcggga ccccttgtag gaaaatgtcc taagtgtggc aacaatattg
     1261 tattaaaaaa atcgttttat ggttgttcaa attatcctga atgtaagttt actttagctg
     1321 aacattttag aaagaaaaaa ctaaccaaaa cgaatgtaaa agaattactg gagggaaaag
     1381 aaaccctggt aaaaggaatc aaaaacaaag agaaaaagcc ctacaatgcc gttgtaaaaa
     1441 ttggggaaaa gggatatatt gattttatct ctttttcaaa ataaacatgg ggctgaccca
//
